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<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MCK9</accession>
    <name>A0A9P6MCK9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AMP-dependent synthetase/ligase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008663</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004777">
        <property type="protein sequence ID" value="KAF9992188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MCK9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043041">
        <property type="term" value="P:amino acid activation for nonribosomal peptide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.980:FF:000002">
        <property type="entry name" value="Enterobactin synthetase component F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.980">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.38.10">
        <property type="entry name" value="Luciferase, Domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF14">
        <property type="entry name" value="PLIPASTATIN SYNTHASE SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9992188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="196" mass="22188" checksum="636221BF2DAF60AF" modified="2023-09-13" version="1" fragment="single">MVEHAQVTRLFDATADWYHFNESDIWMMSHSFGFDVSVWELWGALRYGSRLVIPSHRVIQSPKDLYYLICKEGVTVLNMTPSAFRPLIRCQAETELCDQLRYIILAGEALEPAILKPWYATRSDISPRIINMYGTTETTVHATYNMMEMKDVQEVSSPIGFRIPDLTLYVLDAHDKPAPLGVIGELFIGGAGVTRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MDN3</accession>
    <name>A0A9P6MDN3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008081</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004284">
        <property type="protein sequence ID" value="KAF9993601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MDN3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9993601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="230" mass="25358" checksum="732BA805D70EB4A0" modified="2023-09-13" version="1" fragment="single">ASPVDLSKLGQPSQRPQQKPKQKKDGSTPASPDSANPFEHLSTLDTPPASAHPVGGNGNAQNTKRRSGHRQQTNGAKDGERKDCPRHAEGHPPNKITRKDLGSRRTLLLYYGSDVSLFERIMTYKLGNPDRHVDDAIDAFSEHQGADALANVIYGTQAFDMVFKYTIPDHRRKPLDQHPVEGDGNGATTAQIDEMQELKQHQAETEKHNRHKGQPPTTRPTVAEKDIEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MDQ2</accession>
    <name>A0A9P6MDQ2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_008052</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004257">
        <property type="protein sequence ID" value="KAF9993706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MDQ2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025337">
        <property type="entry name" value="Questin_oxidase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35870:SF6">
        <property type="entry name" value="MGS207 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35870">
        <property type="entry name" value="PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G03330)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14027">
        <property type="entry name" value="Questin_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="225"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9993706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="292" mass="31769" checksum="F79820808BA4EB9A" modified="2023-09-13" version="1" fragment="single">MAKMVSDYLTPLIPGLCASTGALIHLGYGVEFGSRLLIAEGLAYACISYQPATACYIPTAASGATSSWDDISSTKLNAPQKRSPTVSILNMIRNDKRLDGMFDAGFQAKLNVVMSSRVSLLKSYLGMWTSQVHSVSEALLDLSQTSGLLLFTATNRFGDEQQLDKNLANILLATHAARFLVKVLPSEFEKEQLLKAIWMSLVAIFVVQGRPRLITRISSSQSVTADGFPQEKEQESSVTPVVAESEGVEQGSTTKLGMATVYFEPEAMCTLADRWKSLSTEAIHADHRIVPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MDY4</accession>
    <name>A0A9P6MDY4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Condensation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007921</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004159">
        <property type="protein sequence ID" value="KAF9994088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MDY4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043041">
        <property type="term" value="P:amino acid activation for nonribosomal peptide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensation_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF1">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Condensation" evidence="1">
        <location>
            <begin position="85"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9994088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="296" mass="32788" checksum="8D972B1461D7FA48" modified="2023-09-13" version="1" fragment="single">MSFDNKDVLDRYLDAVQKVVDRHDILRTAIIWENLSVPAQVVLRNVKLSIVELSLDPTDGDIINQISRLTDPQDHPQTLADPQPFRNLIAKTREGQGAHGHEHFFVEMLTEIDTPALPYGLSDVRHDGFDVTESHVMLSQDLNNRLRGQAKRMGVSLASLCHLAWTQVVSRTSGQEQVVFGTVLLGRMQGGSGSDRAMGLFINTLPIRIDVRDKSVERSVRQTQADLAALLEHEHASLALAQRCSSVASGTPLFSTLLNYRHNTGNPSDNSDIPGMTVLDGQERTNYPFMISVEDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MED0</accession>
    <name>A0A9P6MED0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_007663</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003968">
        <property type="protein sequence ID" value="KAF9994879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MED0"/>
    <dbReference type="Proteomes" id="UP000703661">
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="15"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="141"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="21"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9994879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="198" mass="22823" checksum="BE327E11F38FF7B8" modified="2023-09-13" version="1">MSVVLVPAGKQKIENLEPADATTSTENVSLKSTQSGEPETVMTYKKKVIPIDDPIPKDAVIMQEYIPGSDVNKHVFMASGALESIEWYQERLSERFSTVVMACTNSQRARVARETDIAAVKKFRDSEKRTEAIEEKYVIEQKKRKAGIAVLKEEIEEYEEEYETITHAFGKYKKYREGFEKTRQTRQLKRNPFSYIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MEL1</accession>
    <name>A0A9P6MEL1_9FUNG</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">BGZ80_007392</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
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            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
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            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003773">
        <property type="protein sequence ID" value="KAF9995908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9995908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="60" mass="6576" checksum="A4B6A29997CE0AA8" modified="2023-09-13" version="1" fragment="single">MPFFKSNKNKSASVASTPAQTPRSSMQAIRNTQVNTMSHAQAIEMVMQKTASYPTPSAMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MF53</accession>
    <name>A0A9P6MF53_9FUNG</name>
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            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">BGZ80_007480</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003842">
        <property type="protein sequence ID" value="KAF9995548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <location>
            <begin position="32"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
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            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9995548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="71" mass="8720" checksum="534EBD15346A3402" modified="2023-09-13" version="1" fragment="single">LREEYDIFPQEIYYCLSEAKIQEFMARWSKQDGLWRPSEDKPRTNPKETEKSPLEQEADELRRKMNNLQRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MFM2</accession>
    <name>A0A9P6MFM2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    </gene>
    <organism evidence="1 2">
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        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
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            <taxon>Entomortierella</taxon>
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    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003625">
        <property type="protein sequence ID" value="KAF9996764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <location>
            <position position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9996764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="115" mass="12612" checksum="4BFCF9A817EECC92" modified="2023-09-13" version="1" fragment="single">MSQISSASQIPYNTNFAIDSTPAASSLVVSFSDTDKDAKDTLHNQIQEVIKQFDNDFISFASVQELVALATIQDYETFLGIVSLMLKVLQDSLIQLNIVLQGLAVTLNSLRSEID</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MGR1</accession>
    <name>A0A9P6MGR1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HTH psq-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_006634</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003283">
        <property type="protein sequence ID" value="KAF9999137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MGR1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
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        <property type="entry name" value="HTH_Psq"/>
    </dbReference>
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        <property type="entry name" value="CENP-B_N"/>
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    </dbReference>
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    </dbReference>
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            <end position="122"/>
        </location>
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            <begin position="33"/>
            <end position="66"/>
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            <begin position="126"/>
            <end position="147"/>
        </location>
    </feature>
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            <end position="183"/>
        </location>
    </feature>
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    </feature>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9999137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="429" mass="47207" checksum="0B1898D56E288715" modified="2023-09-13" version="1" fragment="single">MSASSSKSYRERPSKAPATVLLDHSSIDESVSCFTRRNSSPSGSDIPLPAVVPGQDDRDTSCESAGSSKHYRKAVTMKEKLDIIAYSEIHPEVSAADVARYFGMNRTTVFGILKNKDEIRSQAIPANLGASRVPKRSPSSPVNNNKSQGRLLDCILQVPRKPKMDVEPTRQPEPRVIGGPRPGLVSPSVERRRQFLSDYCLDDIYIFGVTRKYIGKVDCHDCRDGSICSESSTLLILLCANASGTYRNAAPVIVNQNSIIQKSEACNGEVIYDKCSYLRSGTFQNWLSFTDMVFQRKVKALLVVDNATCNLLKTDRDSPDLPILYTDIMGISNGQSSSLQNAFKSMNSKLEKLFNGQYTTSRSPTGLACSSNGQYSAKDFEEQIQKAWGRIPDEVIRAPIQEFVGKVYSSQALCDSRSPRSLNGVTKPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MHC9</accession>
    <name>A0A9P6MHC9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">GATA-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_006388</name>
    </gene>
    <organism evidence="9 10">
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        <lineage>
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            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003152">
        <property type="protein sequence ID" value="KAG0000306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MHC9"/>
    <dbReference type="OrthoDB" id="2162994at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
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        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47172:SF24">
        <property type="entry name" value="GATA ZINC FINGER DOMAIN-CONTAINING PROTEIN 14-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47172">
        <property type="entry name" value="OS01G0976800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00344">
        <property type="entry name" value="GATA_ZN_FINGER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GATA-type" evidence="8">
        <location>
            <begin position="631"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="314"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="422"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="554"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="599"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="670"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="24"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="62"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="93"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="126"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="171"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="248"/>
            <end position="258"/>
        </location>
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    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="314"/>
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        <location>
            <begin position="346"/>
            <end position="357"/>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="440"/>
            <end position="449"/>
        </location>
    </feature>
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        <location>
            <begin position="457"/>
            <end position="466"/>
        </location>
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    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="599"/>
            <end position="615"/>
        </location>
    </feature>
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        <location>
            <begin position="624"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="683"/>
            <end position="705"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0000306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="737" mass="81923" checksum="8E3F1349985D04BB" modified="2023-09-13" version="1">MSKQFTGNSESFDSFEAPRQQRHALSDHNKHERLRHDGAATAPLDHAGKESRYAASELAPMEGERHTAFRQDNHSTVHRKDTRQQQQSDHDQGNNNSDRLPQYSQHAYSSFRPPSDLHFRPRANYQPPQVNSYEKPMSSGSQQSRIDRSNAHTRHHIESHDRGLTHMAIDTASSTPSSMHQHQPPLSSPVDPQSSAPARTPLESLSSSPTRSRHLSQPNISNTVARISDGATDDNSHLGFNDRPNPDVRSSSQPQLNADSAAHARRQLREALPLRLPVINSRNFPQNNISSSAPPSSNLHRLFESERVNQFYQRQEFNRSGNLTNDDGASDDEEGAPASGRTRRNSSRDLGDMRHKFGTDMPTTIDIKSAIEACDVLRRFAEHYQTFEDGAQELPDELDPDSHHRANLQAVRNLNSAMLTGIQPSDRTGVSAADDVESIAQDRDPRVSRDAAMTGGYDDDDEDDDGPAPRFGDGLPSNEMVHELARSAASLFQLAIRIKHWVGMPPEERELDEELNIIRGKRCLFMDGSMPLPTMEPFGPRADDRSMNQTLKGPRENDAPGTAGNQVFRPPVLNGLNQRAHGERRGEYSQFATPYGSYTSNASSQSCMTESSLIKSSDKSEHQKYRKRAKRNPPGRCLSCHTSDTPEWRRGPEGARTLCNACGLHYAKLTKRQQQQEQRRLQNQENGTSSNGPPSSSQPLLGNLSIRNPLIPNLTASMMGPPRLPLPPSAALPTRAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MHF1</accession>
    <name>A0A9P6MHF1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CASTOR ACT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_006204</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003052">
        <property type="protein sequence ID" value="KAG0001300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MHF1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046394">
        <property type="term" value="P:carboxylic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2130.10">
        <property type="entry name" value="VC0802-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027795">
        <property type="entry name" value="CASTOR_ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051719">
        <property type="entry name" value="CASTOR_mTORC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31131:SF6">
        <property type="entry name" value="CASTOR ACT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31131">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13840">
        <property type="entry name" value="ACT_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="ACT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CASTOR ACT" evidence="2">
        <location>
            <begin position="229"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0001300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="301" mass="33421" checksum="6D9D4105B99AAB8F" modified="2023-09-13" version="1" fragment="single">MALDEDLGSTPPHTPIPDHVRFWDRDTYETEEACSADDSLQAKYLSERSLATPPGSSDSASDDDNDAEAASETEDFHATITKQLLPLDIASAQHHGKSAKERSKDSSEDATGCDDSQLFKASPTTATAFELRQRAVRTVPQNTLRCVGLNTDLEADHQPWILKVIKILFYNEKVKEEATRHGRGPVHDAPRFFSFTATSECVSMITDTYILEEFEEHELFMDMETCPLRLIQLDLHRFGLDRFGIIHSVARPLTEAGIELLYLSTFSTANILVAEHRLSDAEKILSGSGTNTPSGETFEEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MI49</accession>
    <name>A0A9P6MI49_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_006159</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003026">
        <property type="protein sequence ID" value="KAG0001569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MI49"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0001569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="112" mass="12274" checksum="7E46D0D623BADB4B" modified="2023-09-13" version="1">MSPRLDVSSILGSSGVWKQKANPAAILQQYLSNSHVLHKNKNCETFGASVNVFVHQMQTPLAPKATRNDALASEQVANSTNVVAMYDDLRQRFQSLCDLYNSKKAPPQSDGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MIL6</accession>
    <name>A0A9P6MIL6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_005818</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002865">
        <property type="protein sequence ID" value="KAG0003288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MIL6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050611">
        <property type="entry name" value="ABCF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047038">
        <property type="entry name" value="eEF3_chromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000634">
        <property type="entry name" value="Ser/Thr_deHydtase_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211">
        <property type="entry name" value="ATP-BINDING TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211:SF5">
        <property type="entry name" value="ELONGATION FACTOR 3A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00165">
        <property type="entry name" value="DEHYDRATASE_SER_THR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="33"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="168"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0003288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="198" mass="22000" checksum="8EE44A03A712603E" modified="2023-09-13" version="1" fragment="single">KLEEWGFDKVLQAFDDKEAAKAGAWTRSLTAVEVEKHLGDLGLDAEFATHSRIRGLSGGQKVKVVLAAAMWLNPHLLVLDEPTNYLDRDSLGALSLAIKDFGGGVVIISHNREFTDAVTVEKWSVEAGVLTVTGNNYTQKNLEKIVMKEEETKVDAFGNVEKVKSTRKLSRKELKDKQKRRAAAKKRGEEVSDSEEDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MJL5</accession>
    <name>A0A9P6MJL5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Eukaryotic peptide chain release factor GTP-binding subunit</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">ERF-3</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">ERF2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Polypeptide release factor 3</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Translation release factor 3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="primary">SUP35</name>
        <name evidence="16" type="ORF">BGZ80_005658</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002788">
        <property type="protein sequence ID" value="KAG0004169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MJL5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003747">
        <property type="term" value="F:translation release factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002184">
        <property type="term" value="P:cytoplasmic translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000288">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01883">
        <property type="entry name" value="EF1_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04089">
        <property type="entry name" value="eRF3_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000503">
        <property type="entry name" value="Peptide chain release factor subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000020">
        <property type="entry name" value="Translation elongation factor EF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054696">
        <property type="entry name" value="GTP-eEF1A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003285">
        <property type="entry name" value="Sup35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050100">
        <property type="entry name" value="TRAFAC_GTPase_members"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23115">
        <property type="entry name" value="TRANSLATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22594">
        <property type="entry name" value="GTP-eEF1A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01343">
        <property type="entry name" value="YEASTERF"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Tr-type G" evidence="15">
        <location>
            <begin position="172"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="109"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="14">
        <location>
            <begin position="115"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="141"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="16">
        <location>
            <position position="547"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00031881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0004169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="547" mass="58537" checksum="A8DA39AE8C203A61" modified="2023-09-13" version="1" fragment="single">MSEQNDKTTPPTAKLSGLSLNPNAGAFVPRATAKPFVPSWMPPPAAAAAAPAPANSSGIDFNRPPPAAVLNKAVEAAPAPSAPSPAIDFNRPPPAAVLSKTVETSVAAPVAKPASPAPKPASPAPKPAAAAEAPKKKVETPKASTPAPAAAPAAEEEEDVVDQETLTEFFGKEHVNVIFIGHVDAGKSTMGGRILEATGMIDKRTLEKYEKDAKDAGRESWYLSWALDTNAEERAKGKTVECGRAYFETDTRRYTILDAPGHKTYVPSMIGGAAQADCAVLVISARKGEFETGFENGGQTREHAQLAKSGGVNKLIVVINKMDDPTVCWAKERFDECVSKLTPFLKANGYNMKTDVVFMPVSGFTGANIKNRLDPKECDWYKGPALLEYLDNLKIADRNLGAPLRMPISEKYKDMGTVVVGKIESGSIKKGATLLMMPNSARVEVQAIFNELEEEIPAAAVGDNIRLRLRGIEEEDIMIGFVLCSPKHPVHAVSKFEAAVGILDHKNIICAGYTAVLHIHNAIEEITLSAMIHLIDKKTGRKSKRPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MLL1</accession>
    <name>A0A9P6MLL1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Exportin-4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">XPO4</name>
        <name evidence="10" type="ORF">BGZ80_004867</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the exportin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002437">
        <property type="protein sequence ID" value="KAG0007273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MLL1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005049">
        <property type="term" value="F:nuclear export signal receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006611">
        <property type="term" value="P:protein export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044189">
        <property type="entry name" value="XPO4/7-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12596">
        <property type="entry name" value="EXPORTIN 4,7-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12596:SF1">
        <property type="entry name" value="EXPORTIN-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="9">
        <location>
            <begin position="26"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00040444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0007273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1126" mass="127009" checksum="7BEDA4B7BA60A9C1" modified="2023-09-13" version="1" fragment="single">MDYPTVLATIEKACEEAQHPATRVQAEKVLIDFKQSPNIVPVCQYILANSNMPSVQFHAASGITGAIVREYGLYQKQDIQHLQTYLIQYNLHHPRLISFVAKQIYQAISVISKRGWLEATQEEQDVVYNHITHLLSMGDQEKRIGLSLAHALVDEFSSRGKASNVGLTWDFHYKTKISFEERHLRLIFEAALKILHEQLQDLMINIGQEVSGSKKPLLSLSILLVESILQWDFSSNSQPVLAGTFADDDDEISRTIIYPESWRSVLVNADVLSMFFTLFPLIQDDNIMTHRVRQCLIQLCGLHGAIFINEEATIHHISGVMKGLLGLINNVASCSSDECLQADYTENMIAITEMIRQLLSFHSIQTICAVPERYDFLNQVALLTIHCLNESAKIPEESESLMGAFDELLVTWVKLVQDSHAAILDRNSPALVADATNLLQFFHSISYRIVEKYIDTRLELAKLNAMVDEESDGFQDWETYGDQLISIAALARLDPHNTLLRVQGLLHDRIESVQNFLNTTHDGSHPEFVMFLYEHLHWLIVITGYIFADNNIGETALVPETLNELSKSQALAQDQLVNIFSNLMSLLDSVSLDSHDVQAISCSPQIALSLFWFLERWVKTYLFASPENYASISPNLLQSYGEASLGGKGSTISEFLISKLRINFIMWNADPDVLSQIIALLNTFGQRTPLRNALLQSEQFPPLVSFFIDNLSVLPEVIHNPLIQSITTIVSYAPSEQLNAHYFNLISTAIETRFAAVLQDKMFQINYQTPEVMNQIMNGLEMFNGLALALTDVNTPMIFNFCSRFFESFIDLVRVYSNFPEVQILVLELYTDLIKNFDVSTLSPEQVSYFHTCLLNLLQTFSAANLGKKRAIAWEEAEDEPYRDVSVVLEMLLSLLEVRGVEQMLAHSPNAVLPSTVVFSGINILIPMIKENMLKIPRVCTLYIRLISRLVESYPERLAELPGDLLINLMASLKFGIDHNILEVAHLTFQAITALALFTYNSSLRNPSEYLAGLNPYLDQFLKLTFEQLLFKRLDVELVDVAGSCVLALVCARQEAYGGLIQELLAASETPLTPDLQQRLSSSFQHLSDAFPTPDVIGQRELSIRDIAMTSAKREVFMRFLMGVRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MM48</accession>
    <name>A0A9P6MM48_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NAD-dependent epimerase/dehydratase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004798</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002402">
        <property type="protein sequence ID" value="KAG0007336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MM48"/>
    <dbReference type="OrthoDB" id="275457at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044877">
        <property type="term" value="F:protein-containing complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05271">
        <property type="entry name" value="NDUFA9_like_SDR_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051207">
        <property type="entry name" value="ComplexI_NDUFA9_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12126:SF11">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 9, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12126">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 39 KDA SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="1">
        <location>
            <begin position="53"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0007336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="373" mass="41386" checksum="3560D3C15AA44A3A" modified="2023-09-13" version="1">MIAGINLAKQSKQAAVSLAQKRFAHDLIVSPKTGRTIIKTGAGGRSSSNGHVVTVFGCTGFLGRYLVNRLARDGAHVIVPYRDEDDMRHLKVMGDLGKIVPMEIHLRNKESLEAAIRHSDTVYNLLGRDYETKNFSFADVHVEAAGVLAELSQKHDVERFIQVSAMNADIDSASRFLSTKAQGEELVRSIFPSATIVRPSFMYGQEDRFLARLAMSRGLSIRINGGNTKVRPVNVSDVAGAMNKMLEGSNTVGETFELVGDKEYTYRELLDFIKEITNLDIGDVNVPKPVASLIAKAMNLLPWQTLGADEIERMMIDDKLTGVKTFADLEMEPTSLELTGIQYLRRFRTNLYSDEPLKKGVVGKKKTFHTSYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MN79</accession>
    <name>A0A9P6MN79_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_003432</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001904">
        <property type="protein sequence ID" value="KAG0008451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MN79"/>
    <dbReference type="OrthoDB" id="655030at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46972:SF1">
        <property type="entry name" value="FAD DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46972">
        <property type="entry name" value="MONOOXYGENASE ASQM-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="6"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="296"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0008451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="393" mass="43348" checksum="47A5CA25304478AF" modified="2023-09-13" version="1">MSTPKIAIIGAGVAGLTLARVLQLHGIRSTIFELDTSVRSRDQGGTLDLHPESGQAALHAAGLFSKFQSYIRSEAQEHRTVDKHGVIHVHIKSEDNTAERPEIDRGDLRQILADSVESGAIQWGTRVHEIKPSQENANKYTVVYNSGHEATFDLVVGADGAWSKVRPLLSSAKPVYSSLSFIELRITDAEARFPELLEVVGRGGCFGISDKKLLGARCNADKTMRIFAGVPIEEDQFSETDAIFSKPEEGRRYLLDKYADWDDRLKNLIRRSDDVIIPRPIYALPVPHVWESKPGLTLIGDAAHLMSPFAGAGANMAMWDGKELALAISDAIKTGKPLADVVADFERRMYEMTRPMTELSASNLKLLTSDATVTEIVETWAKQMAREKPAQEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNI7</accession>
    <name>A0A9P6MNI7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA-3-methyladenine glycosylase I</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_003172</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001822">
        <property type="protein sequence ID" value="KAG0008685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNI7"/>
    <dbReference type="OrthoDB" id="3941538at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008725">
        <property type="term" value="F:DNA-3-methyladenine glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.30">
        <property type="entry name" value="Hypothetical protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005019">
        <property type="entry name" value="Adenine_glyco"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052891">
        <property type="entry name" value="DNA-3mA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30037">
        <property type="entry name" value="DNA-3-METHYLADENINE GLYCOSYLASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30037:SF4">
        <property type="entry name" value="DNA-3-METHYLADENINE GLYCOSYLASE I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03352">
        <property type="entry name" value="Adenine_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="DNA-glycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="226"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="293"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="297"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR605019-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0008685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="304" mass="33981" checksum="578F7EC9CC4CDC14" modified="2023-09-13" version="1">MSRRSSRIATAIVSPVANVVSAAAVTPTKAKKVESTAAITSTKKPSDATAKDIENVINGTIESHEVAPTRKRKAANELLPEPVDDGKGRCSWAASSRHPLLQQYHDTEWCISGGFNRTNRYLFEMLILEGAQAGLSWSTVLNKRDAYREAYDNFDYNVIANTYTSPASNERLLKTNIVKNKLKVEASMINAKAFRDLLLERYPDQAQPEDENGFWHFLQAYKKQESIETGRNGSSENKKKLQNEEPPQAYLTSNEASDRLSADLKNLGFKFVGTTIMYSYLQAVGIELEGTHHTESCFKHPKNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MP07</accession>
    <name>A0A9P6MP07_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Histidine biosynthesis bifunctional protein hisB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">HIS7</name>
        <name evidence="11" type="ORF">BGZ80_003611</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + L-glutamine = D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + L-glutamate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24793"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58278"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="ChEBI" id="CHEBI:58525"/>
            <dbReference type="EC" id="4.3.2.10"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-glutamine + H2O = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="3.5.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 5/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the HisA/HisF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001968">
        <property type="protein sequence ID" value="KAG0008292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MP07"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000107">
        <property type="term" value="F:imidazoleglycerol-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:L-histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01748">
        <property type="entry name" value="GATase1_IGP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.880:FF:000039">
        <property type="entry name" value="Imidazole glycerol phosphate synthase hisHF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00278">
        <property type="entry name" value="HisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006062">
        <property type="entry name" value="His_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050064">
        <property type="entry name" value="IGPS_HisA/HisF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010139">
        <property type="entry name" value="Imidazole-glycPsynth_HisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01855">
        <property type="entry name" value="IMP_synth_hisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21235:SF2">
        <property type="entry name" value="IMIDAZOLE GLYCEROL PHOSPHATE SYNTHASE HISHF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21235">
        <property type="entry name" value="IMIDAZOLE GLYCEROL PHOSPHATE SYNTHASE SUBUNIT HISF/H IGP SYNTHASE SUBUNIT HISF/H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00977">
        <property type="entry name" value="His_biosynth"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="5 9" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase" evidence="10">
        <location>
            <begin position="6"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0008292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="493" mass="53093" checksum="88704569A82D0E01" modified="2023-09-13" version="1">MTGTYLLDYGAGNVRSLVNAVKKLGHDITYVKDPSDILKADKLIFPGVGAFGSAMTSLHTKKYAEPLKQYLALNKPFMGICVGMQTLFEGSDESPEVPGLGVIPGRVRLFDSTMKAVPHMGWNPTRSIQGLGRAKDCGFEQDRAYYFVHSYAVPFVEGSVEAKEWALTTTQYGDQVFISSVRRGNIFCTQFHPEKSGFAGVNILKAFLDGSASTGAEIDAQLLSGSQQQQQVPGSLSVLAPTFVPEPSKDGFTKRIVACLDVRANDQGDLVVTKGDQYDVREQAVGVDGSKGDVRNLGKPVELARRYFEEGADEITFLNITSFRNCPLLDMPMLEVLRRTSETVFVPLTIGGGIKDVVDPDGQLHPALEVAGEYFRNGADKVSIGSDAVYAAEKYYALGGKGDGTSAIETIAHAYGSQAVVISDVKDAVSIPVIASSGAGSPQHFVDVFEKTNVEAALAAGIFHRREVPLEDVKQTLKQNGVKIRNIDAPLAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MP43</accession>
    <name>A0A9P6MP43_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Conserved oligomeric Golgi complex subunit 7</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Component of oligomeric Golgi complex 7</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_003550</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COG7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001945">
        <property type="protein sequence ID" value="KAG0008349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MP43"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017119">
        <property type="term" value="C:Golgi transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019335">
        <property type="entry name" value="COG7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21443">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21443:SF0">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10191">
        <property type="entry name" value="COG7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="53"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="452"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="624"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="713"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="777"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="928"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1020"/>
            <end position="1052"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1116"/>
            <end position="1140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="54"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="650"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="777"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="973"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1020"/>
            <end position="1033"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1130"/>
            <end position="1140"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0008349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1140" mass="125817" checksum="380F0F410B4EFED3" modified="2023-09-13" version="1" fragment="single">MPSPSTRPLAHSQSSGAPLQAPGIVIDPAFTAPDFDVKAWINATLNAALNQQDSSIPSNNITPPSSQSTLANNATTSNGPLRTSASSTSIDNTDASLDASLDLLQTPALDPVLAESTSKSQNAILTQHATSQLTKLHLLAGQTTAVLSATTQDMVKLLPRLTHELDQLRQETKTLQEGIRLVRGDINSVEPSDTTQALDRLKYLDLVKTRMEATHSALREAENWRNLEAEAKDIFAKGDFTRAATRLSEAEKSLVVYKNTNVEGDRMALLLVLKDQLQQQVMDKVREAIEQKDTAACQTLINVFGLIGRQEVFQECYISQRREPLMQQWKRLMEAMNVTLRGSSHVIMTTTQAHTEDSKDFVNALQTFYKAASNTLHDEFSWITSIFSDPSAIIHSLVHDIFSNIDPTMQTALQHVYNTQGDEGSLPILISAFAATESFGTRMERIVSQPLVGNQREHSGNRPRAGTLVQDVNSKDGKGAAHFSRSKSPLGLDPLEIGSIHDPHEWAFILYEPFMNYQRDYGKLEGAHLKALLSKTIPSMAPYRDNIIRNRELAKSSSNLVKIMANTNSLAISLAEGAIGRCMRLTHGFGVPGLLDGLNDFFKDIMDRYTEILLECRQRSGLQVGDSASKDSKQNDYGRGARQSSKYENMDDDEGEDSEGWDEDMNEQDHRHLQMGLRLMDLCRQLCLKLEQLDLKTKRALRGVEELIKLDRTTQDSVHQGSHHHNSSSSEYGFSGPGLKSTTPPPNASIALLQQSNLNSFRLSEILDIVKKSEPKEDRAVITGDGSHDVDRPSAETDPSLEPKSNHLFLQSHQRAVHLTRLCQRFIFDSIYIPLVCPLTDLASLPCWIEGIDQQSQADDVKGARRIHQSTMGGTRTDVIKFRSSPSGYMEELLRQLLELPITFGMYEDDEGLRFGIHMLPYTDRPYELSHHPDSTEQVAGADASGIDGDDDKVLGVGEAASGVGAPVKEEAGGPEELETAEEDDLAVMHRWITSLSKAAMNTMIERLYNPNLEQTKSSTASLVTNIPPTSQRGRLAGTSSPSPSSAGKERQHLTRLSDAGAKQLELDLGYFVETCLQQLAVEPTPNIRALIKALRLSDSGLSMALQQIQQQIEEYKSSEQGSKSKRSSTLLESQQASMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQD1</accession>
    <name>A0A9P6MQD1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">WD40 repeat-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_001774</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001410">
        <property type="protein sequence ID" value="KAG0010118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQD1"/>
    <dbReference type="OrthoDB" id="6262491at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990234">
        <property type="term" value="C:transferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847:SF637">
        <property type="entry name" value="WD REPEAT DOMAIN 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="132"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="344"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="384"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="426"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="432"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="445"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="466"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0010118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="485" mass="52830" checksum="8CBBBDD7AD020BD1" modified="2023-09-13" version="1">MENTNNATKAGGIVHQIPVEQIDFSPNISSDAENFFQTDADIARMAARQGMVNYDKGQAIKVSSKILDMCLGLKGSKGSTLASTSDSVDDTVPEKPIINEDKALVGATAFLAESGHVARKINLETGKSIKLFYGHTGPVTRVAVYLNHLGQERLITGSWDKNIKVWDTETKECLATLKGHTDFVKALVVRAVVGEVSDADGTSRRQVKHELFSASADGTILHWDLETYQPFQGGAGGPWKGHVRGINDLCLTVEEDNEETNDANKNSDINNGGKEYLYSAGSDSTIRKWDITRGQGRGGHCVHVFQHHATTVYKIIVDAMEIWSASADKTAQRLDLETKKVDTKLEHPDFVKSIAVAGPYVITGGRQETVRVWSVATGKLIKEIKGHFDEVSSIIAIGTTLLTASLDATIRRWSLKEKDLIAPAPEDIAKPLSNNPAHTSMAKESTSNSSTTQTSSKEDSKPSMMTEEEERELAELMDSDDDGDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQM7</accession>
    <name>A0A9P6MQM7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Dicer-like protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">DCL1_1</name>
        <name evidence="17" type="ORF">BGZ80_002021</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the helicase family. Dicer subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001488">
        <property type="protein sequence ID" value="KAG0009818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004525">
        <property type="term" value="F:ribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031047">
        <property type="term" value="P:regulatory ncRNA-mediated gene silencing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18034">
        <property type="entry name" value="DEXHc_dicer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00593">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1520.10:FF:000004">
        <property type="entry name" value="Endoribonuclease dicer-like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.380:FF:000001">
        <property type="entry name" value="Endoribonuclease dicer-like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.380">
        <property type="entry name" value="Dicer dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1520.10">
        <property type="entry name" value="Ribonuclease III domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038248">
        <property type="entry name" value="Dicer_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005034">
        <property type="entry name" value="Dicer_dimerisation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000999">
        <property type="entry name" value="RNase_III_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036389">
        <property type="entry name" value="RNase_III_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14950">
        <property type="entry name" value="DICER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14950:SF37">
        <property type="entry name" value="ENDORIBONUCLEASE DICER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03368">
        <property type="entry name" value="Dicer_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00636">
        <property type="entry name" value="Ribonuclease_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00535">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69065">
        <property type="entry name" value="RNase III domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51327">
        <property type="entry name" value="DICER_DSRBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00517">
        <property type="entry name" value="RNASE_3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50142">
        <property type="entry name" value="RNASE_3_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="10 11" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="14">
        <location>
            <begin position="143"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="15">
        <location>
            <begin position="446"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="domain" description="Dicer dsRNA-binding fold" evidence="16">
        <location>
            <begin position="610"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="domain" description="RNase III" evidence="13">
        <location>
            <begin position="993"/>
            <end position="1133"/>
        </location>
    </feature>
    <feature type="domain" description="RNase III" evidence="13">
        <location>
            <begin position="1187"/>
            <end position="1338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="703"/>
            <end position="727"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0009818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1485" mass="168233" checksum="99129F573DF99507" modified="2023-09-13" version="1">MANADDLLLFEEEAFFHKPLQPLKPTLQVPDLLSDSLQHLQLTPALAPASIVPTILPIAPVQVRQDTAPGLARGIAGGRVLPTDPAPIPQNTMPEMLKSSEAGDIQPIAPVSVPQDTPPEAVADDEGDAEARYLVPRAYQDKMYKKALQRNIIAVMDTGTGKTLVSVMLIKEMARRECEARGSAERKICFFIVNNVPLVKQQASVIRSNSKLEVIEMSGPNNTKKFEKKLWNDIFEKADVVVLTAQILLDLFRHAFVKMSRAHLLVFDECHHARKDHPFCLIMREFYHDSPIQERPKIFGMTASPSLDTVSKLLHSANKLERIMDALIFTADEEELRPFIERPNEFVVQYNQSPEYLTTELSIRLNELRSSLPKLESALASEAYNLKHLGPWCTDRLLKAAVESIVESGSRKNAPEDAKIALDIVNYSRATPLECKEDYLSPKVLKLVQLLRVAAEGMSSEFCGIVFVERRDTATALCLLLQELECVQDCLRVQALVGHRDDNDRILRMSMREQNDIISNFRNNDYNLLIATSVAEEGLDVQPCNFVMSIAEEATFEKIKFTEKTIREYFRALDPDRSLSTPDPDDANGLTVTQSYKVPSTGALLTLDSSIALLHYYCSMLAADEFSRVKPELEITSNGTSGFVCDLTLPANAPFRVIQSDRTSTKSMAKKSAAFKACEELHILGSLNDNLLPIIKRRDDEEFIEEDGESNNKEKNSDYPKASPAFWKGESPMEGARLFGCVIELTEKDLENLRGKHRYRTMCLLTYRQIPCTLAPFNLYVEGAARKAMRLCRKTFECPLQNMPYFIAPLVKDYHKSQKLEDAVSWQDIALSQSLVPLPFEEDINDDQVIMESVLTLRNDHNRDFFVKKVLRGFRVNDVMLQDQFEAEHRSWDNAISKGKTVALQSGERTFAQYFKWKYNVSCLDDDIILAAERVHKMRNHLQPAVSEEEKRDEVATIIPLSACMRCPVLSDVLRMSQMIPSVLYNLDSTLLVQEAREKLGITGVSLDHLQVAFTTSSANRDYQYERLETLGDSFLKFASTIRLYIVNPAKDESQLHNHRIRIISNNALRKHAIGLELFRYVSSTPFHRKSWRPTRFIVDGKEWNESQTQMLSDKTLADFIEAALGAAYLSGGTKVGFETAKILRIPFDEFESWEDFHKVYTNAKAKKDSDKERSEVKLKSLHLAEVQEVEKVLGYKFKDPLLFFEAMTHASYIRDEAVCYQRLEFLGDAILDFQVIQYYYKKYPDAPPGAITLIKDASVNNTILGAISLRWGLYKYVKHSSEALGPAIEKSFRSVEEKKCQSATKTLDGEYWNDIYMPKVLGDLVESTLGAVFVDSGFDFDVITDLFSRLIRPFLDDHINFENLTLHPSKLLLEGLQKEGCNNFKFESINSQGNKVDVLRKLGLGRSSQQKQEEGSGMLKCHFKIHDTVVATATGDHIEDLKKEVSFATLAKLNSDSEFLSTLCNCPKRRGPRHVSMLDRYRQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQV6</accession>
    <name>A0A9P6MQV6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_002046</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001495">
        <property type="protein sequence ID" value="KAG0009797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQV6"/>
    <dbReference type="OrthoDB" id="529205at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58113">
        <property type="entry name" value="Apolipoprotein A-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0009797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="173" mass="19430" checksum="2BEBBE867FD84D0B" modified="2023-09-13" version="1">MSLLSRYLRQSLVSTRINATAPLAAVVPHWDRSFSSSSQSFRKDIIKDAPGWDAKKATESEADVKADRQRLPKDMKQLQEETIEITEEERVDVNGQTVKKVTEKVKVNISEDPEITEEIIEDLARHAQNAGTKLGKVTGTIKGKIEDLEETVEEDAAKFVDSIKNKIGHEKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQX0</accession>
    <name>A0A9P6MQX0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Alpha/beta hydrolase fold-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_001572</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001360">
        <property type="protein sequence ID" value="KAG0010346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQX0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF8">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="2">
        <location>
            <begin position="6"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0010346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="286" mass="30647" checksum="20C9B54266E87F5D" modified="2023-09-13" version="1">MACLGGAKVLTIDYRLAPDSPFPAAVVDALAAYLYLLNPPIDSGIAPVDSKNIVIMGDSAGGGLTFATMLAIRDAGLPVPGGIVGLSPWLDLLHSMPSILTNAGSDYLPSDGFTQGGQSSIKKMSELAASIGSKDVLLHHPELPEIQYYASNVILECSYVSPLLEKNFEGTCPMLLIVGDGEMLRDEAIVFVKKNEGDLHLLLYDDMPHVFPMFDFLPTANHALVQAGEFIVKTTTEDKGGLIGKKSYFRVGVDCQQRPLEEDAVVGWEDRLGKLGGGREALVQLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRM1</accession>
    <name>A0A9P6MRM1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein YOP1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_001477</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the DP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001337">
        <property type="protein sequence ID" value="KAG0010442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRM1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd03141">
        <property type="entry name" value="GATase1_Hsp31_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004345">
        <property type="entry name" value="TB2_DP1_HVA22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12300">
        <property type="entry name" value="HVA22-LIKE PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12300:SF161">
        <property type="entry name" value="RECEPTOR EXPRESSION-ENHANCING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03134">
        <property type="entry name" value="TB2_DP1_HVA22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="253"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="DJ-1/PfpI" evidence="7">
        <location>
            <begin position="30"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0010442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="396" mass="43466" checksum="7557AA3A56C5131F" modified="2023-09-13" version="1">MSAHKKILFILTSHDQLGSTGKKTGWYAEEVAEPATILTNHGYEIVFASPKGGKAPLDPSSIDAAKDNKTVVAFLNNNDFTQKIDNTHKVSEFIGKESQFEAIVYPGGHGPMFDLEHDEASLKVTAAAYEAGKVVGAICHGPIALTDVTLSDGTLLVKGKDVTGFSDDEEKTVGFDHAVPVLLETKLKKIGAHYHKADQQWGAKVVTDGRIVTGQNPASAPGFVHYYNAQLDKELSKYPKLNQFQAATGLPKTYVVIGAGAFVFLMIFFNFAGKLLSNLLGWVYPAYRSFKALETPEKDDDKQWLTYWTVYGFVSILESFTDILLYWFPFYFFLKTVFLLWLMIPSFNGAATVYGRVLRPFLVQHGAEIDSSYNSLKAKVSAVASELDGSTSAAAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRQ1</accession>
    <name>A0A9P6MRQ1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Rhodanese domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_001694</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cyclin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001392">
        <property type="protein sequence ID" value="KAG0010194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRQ1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022111">
        <property type="entry name" value="Rhodanese_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020936">
        <property type="entry name" value="TrhO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040503">
        <property type="entry name" value="TRHO_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43268">
        <property type="entry name" value="THIOSULFATE SULFURTRANSFERASE/RHODANESE-LIKE DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43268:SF6">
        <property type="entry name" value="THIOSULFATE SULFURTRANSFERASE_RHODANESE-LIKE DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12368">
        <property type="entry name" value="Rhodanese_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17773">
        <property type="entry name" value="UPF0176_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0195">Cyclin</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="3">
        <location>
            <begin position="209"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="677"/>
            <end position="735"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0010194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="735" mass="82304" checksum="FB767F703F1EDE93" modified="2023-09-13" version="1">MYKHIATNHDDQLQSRIQELISISEAQAALQKDSIDMEFKSRRAEKYGSDSITLNCNCDPSQGTVILFYAYLPIDDPLTLAKLHKTWSIDLGLFGKVKLATEGINATVAGSPASITAYINNLTSLPEFESLNLSQACPGSEADLEKRRYNFFKPTPGCRHVFGEHISIKVVEEICPLGAPELSVYHDPENKRGKLSPRDFHQKLKELGGKEDVVVLDVRNYYESTIGRFPGAITPPIRKFSSFRDYVDRNKDQFSGKTILSYCTGGIRCEKATSYLRQSLEAGGDSQPAKVLMLDGGIHNYLEWVKHEGSAKESLWLGKNYVFDARQSLGLEDVPATEGASPDDGDRLISACQGCSAPCARYVKCDGFGCHRLIVSCVKCSPLTSGGESGMFCCEECRDMGERVQQYVLSGQESAPEPMVTAWLYQDCHFATTNFGQVGIDISASSINYKTKLWVLIIYNMSNTSESQWLFRKEDLYRTPSLMSGLSYQFEKESRSKGVTFIIQVGMHLKLPQLTMATAALFFHRFYMRHSLKDYKFYDIGATCIYLASKTEESTRKFKDVIIACAQKAAKKEIQIDDSSKEFRVWKDTIIYTEEILLEALCFELSVEHPYQFMLSLFNSHYADAQPLAAIHIAAKYVEENLNEGLGDIWRELFEPDVQDITDAANEIMDQYTQFPNKSGRSLDKMLPGSKPGSEYQENGTPSYGGYLNSPAKLATPVYSVETDRPSNGDRSVAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MS01</accession>
    <name>A0A9P6MS01_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">NineTeen Complex (NTC) component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">CLF1</name>
        <name evidence="11" type="ORF">BGZ80_000729</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Involved in pre-mRNA splicing and cell cycle progression. Required for the spliceosome assembly and initiation of the DNA replication.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the crooked-neck family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001159">
        <property type="protein sequence ID" value="KAG0011379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MS01"/>
    <dbReference type="OrthoDB" id="541719at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071007">
        <property type="term" value="C:U2-type catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000245">
        <property type="term" value="P:spliceosomal complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000048">
        <property type="entry name" value="Cell cycle control protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000306">
        <property type="entry name" value="Cell cycle control protein cwf4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000269">
        <property type="entry name" value="Crooked neck pre-mRNA-splicing factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003107">
        <property type="entry name" value="HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055433">
        <property type="entry name" value="HAT_Syf1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045075">
        <property type="entry name" value="Syf1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11246:SF3">
        <property type="entry name" value="CROOKED NECK-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11246">
        <property type="entry name" value="PRE-MRNA SPLICING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23233">
        <property type="entry name" value="HAT_Syf1_CNRKL1_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00386">
        <property type="entry name" value="HAT"/>
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Pre-mRNA-splicing factor Syf1-like N-terminal HAT-repeats" evidence="10">
        <location>
            <begin position="61"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="Pre-mRNA-splicing factor Syf1-like N-terminal HAT-repeats" evidence="10">
        <location>
            <begin position="309"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="668"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="670"/>
            <end position="709"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00037040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF23233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0011379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="719" mass="85317" checksum="3B2BA5C1079F890F" modified="2023-09-13" version="1">MEKRSTQPPKIKNKNAAPVQISAEQILREAKERQEVAIKVPKQKIHDHEELMEYRGRKRKEFEDRIQRSRLHIGEWLKYATWEESQDELQRARSVYERALQVDSQNTTLYLKYVEMEMKHKNIALARNLFDRIVTILPRRDQFWLKYTYMEEMLEEVARARQIFERWMQWEPEEEAWMAYVKFEKRYKELDRARAIYERFVHIHPDPKNWVKWAEFEEREGSTEKARDIFTRAIEVMGEELMEQRLFISFAKFETRQKEIERARVIYKYALDRIPRSKSQSLYNQYVQFEKQYGDKDGIEDVVVGKRRLQYEAELANNLKNYDTWFDYGKLEESTGDVDRVREVYERAIAQVPPAQEKRLWRRYIYLWIKYALFEELEAKDYERARQVYKASIQLIPHKKFTFAKIWLLYAKFEIRQLDVNAARKALGMALGMCPKDRLFKGYIELEIDLRDIDRARTLYTKYLEWSPSNCTAWIEFAKLEMALSDTDRARAIFDLAIAQPELDMPEILWKAYIDFECKEGEWTNARSLYRKLLQRTAHVKVWISWAHFEATVPDEGQTAVARDVFKKGCDTMKEQGLKEERVILLEAWKEFEKAQGTADTLKSVQDLMPKMVKKRRQIESADGGIAGSSQWEEYYDYIFPDDQTQKPYFKLLSKVHEWKARMEKENAEKAATAAVSATTETAPEITTEASPETSTEEPAPTASSPSPEMANGEDSSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSH4</accession>
    <name>A0A9P6MSH4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_001087</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001242">
        <property type="protein sequence ID" value="KAG0010917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSH4"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16454">
        <property type="entry name" value="RING-H2_PA-TM-RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15710">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE PRAJA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15710:SF243">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE PRAJA-2 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="131"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="45"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0010917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="210" mass="23874" checksum="77AB8839AF4AFE00" modified="2023-09-13" version="1">MASYFDDHGLEDPYKARKSNYNNGRSLNPDLSHFMPREDTEDEGNFSSRFPSASGPGSNDFRRLAEMLGAFRVREEPLGDEAHQEFLDNLITQLMDEAGASGKHGPPPASKSFIRDLPFVPLKDVKRDEACIICNENFQENESKAGITKLPCKHFFDRDCIVPWLELHNNCPACRAEVPSDDPDWIKKKRDAELAKYAAEAEIDKDWMYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSJ8</accession>
    <name>A0A9P6MSJ8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNI-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_000824</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001181">
        <property type="protein sequence ID" value="KAG0011248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSJ8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052394">
        <property type="entry name" value="LRR-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24114:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24114">
        <property type="entry name" value="LEUCINE RICH REPEAT FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0011248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="497" mass="52238" checksum="6BF40A77B1CF4281" modified="2023-09-13" version="1">MFDLAKNSLAILLDIDVRNRSNSVGESAGISNTAIGNATPPQNPVMFPPRCLPYILILQSPVFRSLTTSPSAAHLCRINSLGDEGIQSLSEALKTNTTLTSLNLWTNAITTEGALALSETLKTNATLTALNLGWNFIGKEGALALSEALKTNTTLTTLILEYNSIGNEGSLALSAALKTNATLTTLDLKRNSITKEGALALSETLKTNMTLTTLDLGYNSIGGEGALALSEALKANTALTTLDLSTNSIRKEGALALSEALKTNTTLTTLILVSNTIGTEGVLALSETLKTNATLATLNLWNNSITKEGTLALSETLKTNTTLAKLTLGANATGSEGALALSEALKINTTLITLTLWKNSIREEGALALSEALKSNTALTTLDLAMNFIGKEGALALSEALMTNTTLTTLILEHNSIGNEGAFALSAALKTNTALTTLDLRRTSIGNEGALALSEALKANKTLTMLDLRGNSIRKEEALALTEACKPSVILRIFYIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSY7</accession>
    <name>A0A9P6MSY7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histone H1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BGZ80_000065</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001006">
        <property type="protein sequence ID" value="KAG0012294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSY7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045814">
        <property type="term" value="P:negative regulation of gene expression, epigenetic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15502">
        <property type="entry name" value="PHD_Phf1p_Phf2p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005818">
        <property type="entry name" value="Histone_H1/H5_H15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12628:SF10">
        <property type="entry name" value="HOMEOBOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12628">
        <property type="entry name" value="POLYCOMB-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00538">
        <property type="entry name" value="Linker_histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00526">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51504">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0010">Activator</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="11">
        <location>
            <begin position="170"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="H15" evidence="12">
        <location>
            <begin position="431"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="101"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="372"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="504"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="598"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="765"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="828"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="883"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="944"/>
            <end position="1037"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="10"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="104"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="388"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="608"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="620"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="642"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="662"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="676"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="691"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="769"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="828"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="856"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="883"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="944"/>
            <end position="1005"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1016"/>
            <end position="1037"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0012294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1037" mass="111892" checksum="D58C6C834AE06AED" modified="2023-09-13" version="1">MSEPLKDINTENGTSGSSQHGAVGAATEISSQDEHMQVHLSSITVKPASTNMNLQHSTIPAIKPKSKKHMPSHRRSIDAGEDQNDFEMDESIQKSTIMMKRLRSKSETKKSENEYGAAKDPGQLQLEQAPAHKRHVQENWKSGAIGLTSNLPMFPSDPRVYMQLQPAREDGGCVICLQANDSPDNQIVLCDSCDRGFHQRCYTPPIDNKFVEIASLEWTCYACSLPLNTAGSQGLSALTEDMSLTGEQVSQDVKESYLWSLPKSSLVKLITRIETNSPAVRLYPSRLSSPITSQFDYSNLSLVPPTTDTPAPVSLPQPSNQDMTMSPLSPAYQAMQGVQSDYFESLVTHFPPAMPLSSIQEVNDNFPLSTATKTAASKARSGTEDPSKSSTPGASSQPTTPSTPKNTVRLSGGSGPGAGVTGPYHSVKAQELPPYEEMIFMAIADMKQEAGSAPKAILDWVQGHYPVPETFRASCGQAISKAAKKGRLLKEGAMYKLKPGYNYPRRVSRHAGPTRARSHSYNSTLPPGVPSIEGSSRGSPMTLQHDQINSIIDANLYGMLPSPPFRVAPHPGTPGFPGTPTQNVQQRLQQPVHPFKFDGRPMGLATGIQKNPNQDPNTGSGAGMDSKGGNGVSGLIGLGVTNMASGQSGENDNGVESDSTRRSSSMSSVSSGPHSFTGTFQNTDTHSRTLQAQAQAQAHTQQIQAQIQRRPSQQHIGQDRVWAMAGSSGSNQPQGGLVGVVLSGRVGVPVPSPLQFNASSFANLGPMTLPSQQPSQPHASIPPQVSLPQGPMTINTSLTGMGGVGQGPATGTSMFSPMFIPQNLQFSQQPLQQHQVHQQQHFGGSPSSARPFGSMSLPSSPQDMTPQMRAQISMHTNQLLTNAPQQSMTSSQPDTPTGIQLNSNIPVDPSMRFTQAFNGAQGSMMLYQQQMQLAFQQQQQQQQQQQQQHQQPQQQQQQQPHQQQQQQPHQQAQQQQQQQQLQQQAQQQAKQQQSSPSSNMAAASSGNLQLPMDINALQTQESSQYATGSSEKSPMDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MT33</accession>
    <name>A0A9P6MT33_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_011760</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000988">
        <property type="protein sequence ID" value="KAG0012408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16922">
        <property type="entry name" value="HATPase_EvgS-ArcB-TorS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17546">
        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45339:SF5">
        <property type="entry name" value="HISTIDINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45339">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55781">
        <property type="entry name" value="GAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="Homodimeric domain of signal transducing histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="251"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="9">
        <location>
            <begin position="2193"/>
            <end position="2249"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="2324"/>
            <end position="2574"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="8">
        <location>
            <begin position="3094"/>
            <end position="3239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="131"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="279"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="418"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1910"/>
            <end position="1941"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="2800"/>
            <end position="2826"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="2846"/>
            <end position="2866"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="2942"/>
            <end position="3022"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="3037"/>
            <end position="3071"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="3166"/>
            <end position="3192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="139"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="286"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="422"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1910"/>
            <end position="1919"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1920"/>
            <end position="1941"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="2811"/>
            <end position="2822"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="2857"/>
            <end position="2866"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="2955"/>
            <end position="2972"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
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            <begin position="2986"/>
            <end position="2996"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="3005"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
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            <end position="3054"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="3181"/>
            <end position="3192"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="4">
        <location>
            <position position="3146"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
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            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
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            <dbReference type="EMBL" id="KAG0012408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="3239" mass="357175" checksum="62DE8E17145F7B79" modified="2023-09-13" version="1">MTIEHDPYSNTANADQNMDLDPASFDTTSTTTPHDSHHPISTTASSAVSIPDTSKCPNATWFHRPKVQPSSISTTATSSLMSSTSLIKTNHGTAEGSPTPIAMLPAKTRAPATLYASLQSALAAGTVVGPAPRLRQHNHNSPTTQSDRTMGPYSSQLPASIGTLHVNPLPQLPVDNEPTHHNPYRPPSHTNCRAFVPPRVPGYEFIGGSQAGNMGLMMGRRISDGVLVTGKLHQIRTLLQHEYRILKRLKITNAKYIPDGPFPRQFNANNQEEARRVVESDCSTEPTKDKETSHRECRPKPGAKKVFYEAGGVETEKYFNRVVEDFIDLEQEDMSILILERLGHNLLSHTHHPFLGLEGIEGLNNSEIQKLNLGSPFPDVYTFLIFALKAASILEALMSANLAHLAICPTALHWAPPRTDVETSNSGDGSKVDSNASKPPNHALYPPLKDIDINNTTLRLFDFTHSKILSHERARAPNNIAEWQIPGYLEYHLQFLAPEQTGRAETWMDHRTDIYGLGATLFALLTMQFPNTGNDSVQILQGVLSRDLPPVRDFRPDMPSIVDDILRKMTQKQPSRRYQSAFGLKQDILQCLNMLKKSGQIDSFELGKHDISYQFVLPNAIFGRNMEHKMISAAIAQAASAYQQSLNAQMLDGDDDVEDGATQTPTKNNADYYIFEDDIVSLQSQASSKIPLSSKTLLRTPKPFNGVQSVHRGPETTDPIVRVVFVSGASGVGKTFLIRGMAPVARNSGLFAAGAFDAEGSAPYSAILSCIQSVLQQLLAQHTDALASLFVAIRTAFEPSSGIGVICDLVPELRYFFGGSEMPESKDVPLAHSITRFHFLILKLIRVISTHFFMTWLIDDLQFADENSIDLLATLVNVNKRLPIVLIITHRDTPDCLMKVRHILGGGNTVGSQQPSGLGALGAVHHDRLMDDLSAKGGMSSRPMSKSSALRGTGDSLVVRGGGGVRFIRLQNPTTDSIQEFLVALLHREKADVAPLAKVLSQKSWLTIRQLVLELYRNQTIYFDCGTREWAWESCPDTLAETVRKLTGEEYSFLDNRFRALDCNTKRALVCASVCGPSFTIQDLQQLITETYSWTIAKSKNCDTAKIETTASEAAPEAAPTVEAIPATDAAPAAEALVTSTDSHPNFNRGCDAMAGIQCAIREGILIYTSVTDHLRFHHGIMRKVAMDLLENPEDMERLHFDITKLLFNTPGQEFRIAGHVLQCLKLIKKRMAMGARTSDDLHDELMKTNRSHAEEQWQWSDSEIRKTVEIDTRSFRRNLSLAGEKSQKSGAQDMSLAYWSAALSLLPGNCWDQPPERTNDAVDNDISRNYPTSFPQSPAAFNENLLYREALKLHLQCIEAERWCENFDQAMKICDVVLSKVNDPIDRARVYQHQIEMYVWAYSSPDKAMATTIQCLHELGLSKDFDFNPSEDEIRDMFDKTHLMLMEHIPILEANPPKLCTDPNVAMMMEVLQVSSASLYYCSIPFISCGIVQSMRLTCEHGITKDSGRALVSFALTYSTWFNRLDHAYEYGKLACAISNDNHHVKFLFYVAVQQWGEHVAASIPALEETLTAVDLTCDRLFHTAGMIHVSVMKVLVARVPLNDLMTTTIELLTKHIEFGPKSHGVEVMQGILQMIKCLMGRTMASDPETIFDDVDLSDIKNPTNGQSSSNKKVLTLVHNDSTYQMLKALAAFIFGHYAYVQEVTDAWHDDPKSIMNFEGSWITHAVFTIVGLSLANILRTETDPEVRKKHKRRLFKIRSQMEVCAHTFPTNHAAMYYLLEAEMADQGLTPESNENGETAGVEGVDGPIIDKMKVLLLYEKAIEYSVDGDFPLHKCFSYELAAKAHLRYGLLTSSKHMMTNACKVYQTWGAKGKVQWLHNTYAELFPAQPEADATAVKRRLFYRPSDSGYSTNRSLSTAGPNNSGATSSGSGGSATSNSPWMAGSPKSIYSPTTFGPDAVSAAAAAMVGSNMASSFQSGCPSATSTSSSILTAPLYSLQNTWLSSPQTPEMDNADLDVLDFSSVIEAMQVIASEIDLDLLLVKSLGVLNQSVGAKRCCIIISKDHELVLSASLGDSGRCESVNPPMEISQCSSLFHGVINYVVNTSAPCLLTNAKDDPRFCADEYLSKQRVDLKTLLCAPIIHKAALVGVLYMEDFPERAFANKRMLVMNLLVQQLGISITNALLYQSVLQSETKSTGLLENMPCGISLWDASGNNCLYVNSTWEDMTGFTREEIMSSETSILAHPDELVSEGLAWKERVQEGVPCQWECRYSLKDGTYRWGIVRMLPIMANTDNRILQWVTVTIDIDDQRKAVQLKSNFLANMSHELRTPFSGILGMLSLLGDSSGLTHEQFEFVDMAKASCEMLIRIVDDLLNFSKLEADKVTLEYIPMCFEEIIGVPLASRKGLELIILPDVNLPILLVGDPDRMKQILMNLIGNAIKFSTSGNVVIKYWHETRKRESIPSKKAILASKGHFDKFLSKMEIDLGDESLLGDEVVLHCSVTDEGIGMTPEEQKMLFVSFQQTDSGTTRKYGGTGLGLSICAQLINHMHGKVVVESEKGKGSTFTFTAKLNTSTDHDYEQNPVESKRIKDCGDAINIRGEALRSKRVLILSPNKSLREQIMITVLGAECMEFDGVESAVQSGAIGILGDPTGCCCSDIIREGIVDSNVDFAESKNGGYSCCQGSSPSRLHPEGTIRQFDFILVDHVLDSKELDCIYPSPSIAFVLLLAPTTETLRWILPPAQKISDPMDSDETDSSQVDVGGRGRIQKISEVGFAGNIIGQVRSSSYLSKIRVQPSKSDGVTDLEADASSGSHSRTSSGSRPKRLMRIPSELFKRKKNSIRTTNGVKKKRMSETLAKSTKTMVHGYSTSKTPGLMTANTGAAACNAPPCSSFQVCRMIKPVRRLKLLQILYNALLHHEQKLSGEGNDDDDGHANLVELSEESEIEDGDGGASLQRSRSQSEATDGTASPLSSPPARVSLKRKISREPLAEPLEDRTDDDEVQSSSSSSGANSSVGSPRDEELLKNRRHADKTAKLHALSSVAHSSPSSSSKVKGNSANRRTIDNNLPKRARNNDALTLLLTHEERKRCRGINVLVAEDDYVSQKILEKQLSKLGMNVMIASNGQEAVEQWLAVERGHYTIAIFDHHMPIMDGLAATKKIRSLEEEQRKNSAVEGDESNNAESSDGNSNRPMQIRIPIVGLSADIQLATKEKCIKAGMDEYMTKPLLKKTLAIGMSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTV0</accession>
    <name>A0A9P6MTV0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_011111</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000853">
        <property type="protein sequence ID" value="KAG0013384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTV0"/>
    <dbReference type="OrthoDB" id="64477at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051531">
        <property type="entry name" value="N-acetyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43792">
        <property type="entry name" value="GNAT FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G00765)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43792:SF16">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="25"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0013384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="217" mass="25063" checksum="D414E29FE876305D" modified="2023-09-13" version="1">MAEQQQQQLFVKAKAESLRLSFDPPNAQDDTAMGAMLSDLETMVFLRYMAKEWQGGWTAEELVTRRENQCKAMEEKRGSTYYIHDKSTGELAGVMGANVINHKDRNAVVGIILRKKYWSGGYGTEALYELMRGLFEDLKMHKLLYETTESNVGMRKFLEKTCGIPMAYIRKEEVWCLATQKWVSLWQYEIFEDDWPRISATLLESMKRGAFKQIATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MU30</accession>
    <name>A0A9P6MU30_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Vacuolar protein sorting-associated protein 26B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">VPS26B_3</name>
        <name evidence="4" type="ORF">BGZ80_011096</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VPS26 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000850">
        <property type="protein sequence ID" value="KAG0013411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MU30"/>
    <dbReference type="OrthoDB" id="3821113at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.640:FF:000010">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.640:FF:000001">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 26A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028934">
        <property type="entry name" value="Vps26-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12233">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING 26 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03643">
        <property type="entry name" value="Vps26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0013411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="313" mass="36874" checksum="789867AD41AF7E3B" modified="2023-09-13" version="1">MSVANLFGFAAPIDIDIRFNDQDKRKQIEAKVDKDRREKFPLYFDGETVAGKINIRVKDGKKVEHNGIKVEFVGSIELFYDRGNHYEFRTMQQELAVPGELRNNTTFDFEFKNVEKQYESYHGINVKLRYFIRVTIQRRLADVVKEQDIWVHSYVMPADGNNSIKMEVGIEDCLHIEFEYNKSRYHLKDVIVGKIYFLLVRIKVKHMELSIIRRETTGAPPNQYNESETITKFEIMDGAPVRGETIPIRLFLGGFELTPTFRDVNMKFSARYYLNLVLVDEENRRYFKQQEITIFRRQVDDEAEDGLALTERI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUE5</accession>
    <name>A0A9P6MUE5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_010717</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000779">
        <property type="protein sequence ID" value="KAG0013987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUE5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0013987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="185" mass="20415" checksum="614DF236815E0937" modified="2023-09-13" version="1">MIINGRDDALGILPTLPELLDSSAALQKRLLNNPGLSEMAIIEIFRLNDLEVDQSMPILSSRGALTLVNENAIENLVQGVHSHFLKLESIGLPVPPLDDIEVAIDRKAKARVIFSKMRDPLSPLNPDDVIRKLNEYLESSRSEAVEVIGYLSDMATSTTEHSLSSAGETRVDWKAFVQKLDQLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUT7</accession>
    <name>A0A9P6MUT7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Adenylate cyclase</fullName>
            <ecNumber evidence="3">4.6.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">ATP pyrophosphate-lyase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Adenylyl cyclase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="primary">CYR1_2</name>
        <name evidence="17" type="ORF">BGZ80_010381</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 19">
            <text>ATP = 3',5'-cyclic AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:15389"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58165"/>
            <dbReference type="EC" id="4.6.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the adenylyl cyclase class-3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.1" evidence="3"/>
    <dbReference type="EMBL" id="JAAAID010000716">
        <property type="protein sequence ID" value="KAG0014540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006171">
        <property type="term" value="P:cAMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17214">
        <property type="entry name" value="RA_CYR1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050216">
        <property type="entry name" value="LRR_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000159">
        <property type="entry name" value="RA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055071">
        <property type="entry name" value="RA_PHLPP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051:SF1">
        <property type="entry name" value="RAS SUPPRESSOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23010">
        <property type="entry name" value="RA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00364">
        <property type="entry name" value="LRR_BAC"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50200">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0115">cAMP biosynthesis</keyword>
    <keyword evidence="5" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="10" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Ras-associating" evidence="15">
        <location>
            <begin position="522"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="domain" description="PPM-type phosphatase" evidence="16">
        <location>
            <begin position="1270"/>
            <end position="1527"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="14">
        <location>
            <begin position="1574"/>
            <end position="1713"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="229"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="296"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="345"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1015"/>
            <end position="1059"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="44"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="97"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="234"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="296"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="345"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="1015"/>
            <end position="1045"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="17">
        <location>
            <position position="1784"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00032597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0014540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1784" mass="198705" checksum="24CA1E8B585138C9" modified="2023-09-13" version="1" fragment="single">MAPTQPARRGHRKGSTSSSISIVDPSSTTTTTVPERRPSAGSGYFSQAHHNGRTNPDQSTSASNTILTNPSTKPPYPNDDRLRHQNSRTLLDAQAQSTTLSNASTSSNSSKRKNNKGSGESNGMLSFLRGSSRPPSPDVETLYNATHTRKTSFSSHNGSHRAIAMSTSMSSSSIHSNSSATMANSLQQHNNASQNGANYNGGSNIGQQQYYHHNVTGQSQSHPFDIDAERRQSTESYSRSSSPERTSEHQQYQQQYSQQHQYQLQQQPQKNAFPTTPPAHLRIHQRTDSIKYAMEAQHRRTKSTDYGDAHGKRPGQDQETHLASPAKESKKPNIFNLFKKKPLLSHNQNSSTSQHQQQQHSFYANQHGHNERSRKYSNDELYISSGPSTTLHPFGMGLFSDHDNYEKRHGSDGGDSTHRALHYMTGKKGSKKDHLDILPGFVVADLQDMSGIKGDSKHARSATALAGTETWHAPESWGVQPPSAAAGGAARALALASEDLASEDLGNGDFENWDCNQKKLSTIRIFKPDTTYTTVNCEFNASASQLTTILGKKNFKTDTSKYHLYIHRNNIVRQLGPHERPLNILRRLLLQFGYTDADKLEELSGKDNSFICRFTFAENGAPLITEADFKEGDNFSAVNLQRKCLPTIPIFLYSRARDIVQLNISHNQRMDLPLDFIQNCNFLRELFMAFNDLDRVPSNIRSIAHLQVLDLRGNRIKTLEKSGLEETRELSILYLQSNRLDSIPDSFQSFEYLRVLSLSSNNFSKVPMVLFQILTLEELDISFNEISEIPEEIGSLKRLKKLLLFGNKISPYLPKAMSELTRLRKLDIRQNGILNLNAVNDLPALEDLLVDYNTNIILNDSFKSLSRASFLKCNITEINIRGTGDTLSLLDMSSNKLASLAPTLFEHLRSLEILKLDNNNIGSIPGTIASLKNLKSLSISNNFLSSLPEEISQLESLIELDVHGNSLSELPVAIWRCPLISLNASSNLLASFPDPPKILPTTNLCAPPLSSSSSSVSLNESESATTLPPSSNASFAASPTPLRSKPLPPPPVPLLSTPSGRAPYAPPLAASLNILSLGDNQLPDDVMYPISQLKNLLVLNLSHNYIMEIPRGKIPNPASILELYLSGNQLTSLPAEDIERLRSLRILHVNGNKLTTLPAELGKIHKLGVLDVGCNMLKYNISNWPYDWNWNWNLELKYLNMSGNKRLQIKRQNLEPVLLGNSKPGNLSEFGNLTRLRILGLMDVTITDNVPENSVDRRVRTSMSTVDNMSYGMADTLGDNENLCIWDHVHPKFQTKEDESLFGLFDGRSNKLKSGCHITSNLKDRFGSYFKIELEKLEGNDTVVSALRRTFLGLDRELWPLIHDEDSKRGASALVAYIKGVTLYCANVGDAIAVLVKKSDTFEVVSQKHTPWNPTEVSRIKRSGGFVSEKGLLNDELDISRSFGQYHLVPFVNSNPYIMTTTLSEEDDFLIMASNALWDVMSYATAVDIARAAKRDYGDLMYASQKLRDIAISYGAKDHMVVMLIGVGDLFKKKEPLETPEYHQINKRPKAPEGPTDALKYLKPEIEPPQGDVAMVFTDIKNSTKLWENIPTAMGIAIKEHFHVMRRQLRSIGGYEVKNEGDALMASFSSVPAAMLWCFKVQELLVEADWPQDILDSVECRPIFGATDPVHPMYRGLSVRMGIHWGQPVSDRDQVTRRMDYYGPMVNRAARICDAADGGEICVSSDVINVIQHLLDDPGLDESDSPQAEHVREIKKMGFGVIDLGERKLKGLETPENLHLIYPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MV79</accession>
    <name>A0A9P6MV79_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Minichromosome loss protein Mcl1 middle region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_010757</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000785">
        <property type="protein sequence ID" value="KAG0013935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MV79"/>
    <dbReference type="OrthoDB" id="427368at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043596">
        <property type="term" value="C:nuclear replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057646">
        <property type="entry name" value="WD40_WDHD1_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022100">
        <property type="entry name" value="WDHD1/CFT4_beta-prop_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048591">
        <property type="entry name" value="WDHD1/CFT4_hel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19932">
        <property type="entry name" value="WD REPEAT AND HMG-BOX DNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19932:SF10">
        <property type="entry name" value="WD REPEAT AND HMG-BOX DNA-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20946">
        <property type="entry name" value="Ctf4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12341">
        <property type="entry name" value="Mcl1_mid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24817">
        <property type="entry name" value="WD40_WDHD1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="WDHD1 first WD40" evidence="9">
        <location>
            <begin position="11"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="136"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="228"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="WDHD1/CFT4 second beta-propeller" evidence="7">
        <location>
            <begin position="389"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="domain" description="WDHD1/CFT4 helical bundle" evidence="8">
        <location>
            <begin position="680"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="813"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="934"/>
            <end position="981"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="994"/>
            <end position="1058"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="814"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="849"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="937"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="950"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1025"/>
            <end position="1035"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1036"/>
            <end position="1049"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF24817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0013935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1058" mass="117455" checksum="CAA70BADE60098CE" modified="2023-09-13" version="1">MAKDMVKVTSRWAHGAEITGVAYTPDGSYVVTCAEEFTMHLFPQKEGNLDSSADKIETDEPVTCIVVTQGYIFTGSSDCMVRKYDLETQEHSILVRYDLKIRCLAISPDETLLAVGTESTEIRIVNMEDPEKCWSFKGHKKAVNSLSFDPLGEFLISSSCDGTVIVWNLKSKDTSPVETIPVMSPTTTDSNVKIPVAWHPSNEYFVIGKDKDIAAHHRLTWKKSFTYRTGSSDAVQCLAWSANGKYLSASSTNAELWIWQYKEKERPLLTHKHKNGGITDIAWAPNANRLVFTDTAGELSRWEDVISPEKGLPFDKPKPDPLAGLFDEAAVEDHGIEDQEMAQEYLSDNESLKDFIVDDDNSAYLQKKPAPNSLKPTLKSFSAKELHPRFQPGSTSLRDERRYLAFNLLGLITSVNHGTHATVSVEFHDKVAHRGYHFTDNFNYSMACLGLTGALFAAASAGETPSTVFYKTYDSWVTKSEWQISLPEGEDATAIALNAESAIVATSRGFIRVFSQSGIQTALFSVGSVVAAAGKDDMVLLIYHQGEPFQGSQNLGYSIYNVETGQRIQQGSVPVSDNIFIKWLGFSEGGIPAYFDSKGVLYILNYYRRVDQGQWTAIADTTLVETDSDQSPHYWPIGFTDGELSCIKCRRGETEPSFPKPFVAELPLKMPTLYQDTPAGQHEEAWLRQKILSGLNKDEKIAMSIERTDNGAAKKELEMDKLALRMIDLACKAERTQKALDLTAMLCNLKSIDLAVEIARIHSLHSLMERMNKVKEIKMIEEEDRDPNADLDLIMANPTLAVSTTRNQEVYKVSTREEDRELERKTLQRKEPIKPNDPFGRRVVKDSNKSTTAQNGASAGSATSNPFKKKGGPSAMGPSKGFGSIVEIDKAAKPITERASDLFEAADCLAADEQRARAQKEQSRQDDLFKKRKANNTVAGAGSATVGGQKTLSMFNRPALSSSTADAKRFKKQQDDEDRDMDMIMDADDFLEETRQDDDGNEIESQVSVRIPATQESEYLEESIEETRGHLEKTRVASSLSPTRNTSSILAGFKFNGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MV89</accession>
    <name>A0A9P6MV89_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">NRC2_2</name>
        <name evidence="13" type="ORF">BGZ80_010739</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010000781">
        <property type="protein sequence ID" value="KAG0013973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MV89"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05574">
        <property type="entry name" value="STKc_phototropin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000121">
        <property type="entry name" value="Serine/threonine-protein kinase nrc-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000078">
        <property type="entry name" value="Serine/threonine-protein kinase nrc-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45637">
        <property type="entry name" value="FLIPPASE KINASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 13" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="70"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="12">
        <location>
            <begin position="358"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0013973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="428" mass="47554" checksum="4AA3DFCBEEECD295" modified="2023-09-13" version="1">MTTSSMTTTATDSTLGSSTNGASKPNGGLNLSIPKSPNGSAVDLRRGAFRRTYSSNSIKKKTVEVTPSSFVKLRLLGKGDVGKVYLVRQKDTDRLYAMKVLSKKEMIKRNKIKRAFAEQEILATSNHPFIVTLYHSFQSEEYLYLCMEYCMGGEFFRALQTRPGKHLQEEDAKFYAAEVIAALEYLHLMGFIYRDLKPENILLHQTGHIMLTDFDLSKQSLPAGEPTIVKTGSPSIPPAIDTKSCIANLRTNSFVGTEEYIAPEVIKGCGHTSAVDWWTLGILMYEMLFGVTPFKGKDRNATFQSILHTDVQFPDHPGAQPISSLCKSVIRKLLIKDDQLRLGSKAGASDVKSHPFFKSTNWALLRHLPPPIIPQPSFGADAINFRQMQESVSLDIEGEELVLQQPGVKNLFANFSSVTLHHDGDDDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVB5</accession>
    <name>A0A9P6MVB5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transmembrane protein 41A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">TMEM41A</name>
        <name evidence="7" type="ORF">BGZ80_010130</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000673">
        <property type="protein sequence ID" value="KAG0014965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVB5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045014">
        <property type="entry name" value="TM41A/B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43220:SF21">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 41A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="131"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="410"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="463"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="263"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="328"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="361"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="525"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="27"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="63"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="276"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="328"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="381"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="538"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0014965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="567" mass="62874" checksum="6AFA1F9616A1B42E" modified="2023-09-13" version="1">MQPSSPQDHNGDMFGDQAQGSTPTICTGRSRSSTLTTTSTGAVDIAAAAISSQLDHVMRPRRPSLSSRPSAPNIRSAPALPAVTLPTTAPSHTLYLPEPTLPQYHLVEETKEKTLSTPSWANIQLGFLPRIILLIGIFCASLGGLYLLAQVLPPLSLPKSIDDVKIDAAILQEFATATYEGWIRTFWVFSIVYMWKQCFGIPGSAFLNILAGALYGPWFGTVLTSLLTTFGSVLAYFMSFFLMEPILNRYASSRLDQMRLQVQKKTMGSKKKRRNSATYTNIQPSTNASTIESPGIATHNSHSESTSSQGTHLRPRAGSVTLRRMDNADQNISSHYPYPNFTTKNNEIESQENDRLYVEDRDNENPALPTGQQNDVTSGQEIDDEGDDESEGTSLFMQLLLIRLFPLTPYWFINLASPLVGVPVIPFMASMFLGCMPYNYICAQAGAILSEIHELRDIYRQPWILFQVIMVLILSTAAVFVSKRAKKKQVESEEEKNGSGESETFGDEATHHLLRSNFEDDEQYNSQQYRFEGDQGSIPMSSLGSQHTAHSGSNRRESAIIDIPTYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVL8</accession>
    <name>A0A9P6MVL8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_010748</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000783">
        <property type="protein sequence ID" value="KAG0013960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVL8"/>
    <dbReference type="OrthoDB" id="4540492at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015149">
        <property type="term" value="F:hexose transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045263">
        <property type="entry name" value="GLUT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23503:SF8">
        <property type="entry name" value="FACILITATED GLUCOSE TRANSPORTER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23503">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="68"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="158"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="186"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="327"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="368"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="395"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="421"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="458"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="483"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="12"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0013960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="530" mass="56563" checksum="DE8ACD1A59B1D7D7" modified="2023-09-13" version="1">MDSRTLTTLPRHMLYSGVVTCLISLSTGYVIGSPNIPEAAIRGQDGACGPSPYTIHAGFPNCFEFSDLLWGFAVGSFCLGACAGGLISGGIQNKIGRIKTMLLSDFVFILGALTLGLTYHQAQFIIGRVIVGFACGIGGVVAPTYLGEIATIQGRGTLGAFHQLFVVIGIVISNLVGLAWSSPPGWRVVFAANAIPALLQCFLLPSLVESPKYLVSQNRLKEAKESLQKLRGPEPEVDVHQELDEMIALLIGDRVIEEAADEEEEISDPASRAAQVIPAVQRGDSLATVKTQLTLVHTPNVHENMADAPSNDSQDSYGIIELFRSECCGLAIIGILVHFLQQASGINGLVYYSTSFLANVFGTNNSKYITVGISFCSLLSTTASVFLINRLNRKTLMMTSFVGLSISSLLLVIGAYCNVGILVVVAVFLYIATFAVALGPIPWLLLPELLPTYAVSPASSVATGVNWGTNFVVGLVFPSMTKAMGSGTFLLFGAINVFGVFYIWRFVPETRGRSTEAIMAECGVPPRSKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVP8</accession>
    <name>A0A9P6MVP8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">U three protein 7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">UTP7</name>
        <name evidence="11" type="ORF">BGZ80_009794</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in nucleolar processing of pre-18S ribosomal RNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000618">
        <property type="protein sequence ID" value="KAG0015543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVP8"/>
    <dbReference type="OrthoDB" id="10251154at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000378">
        <property type="entry name" value="U3 small nucleolar RNA-associated protein 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012952">
        <property type="entry name" value="BING4_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040315">
        <property type="entry name" value="WDR46/Utp7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14085:SF3">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14085">
        <property type="entry name" value="WD-REPEAT PROTEIN BING4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08149">
        <property type="entry name" value="BING4CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01033">
        <property type="entry name" value="BING4CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="4 8" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="263"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="BING4 C-terminal" evidence="10">
        <location>
            <begin position="344"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="458"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="491"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="459"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="491"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00076453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0015543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="522" mass="58762" checksum="0F00BA0BB2E15A70" modified="2023-09-13" version="1">MVEKKKKDPVLAVVPKYARGDSNAALDGVNKLKDRKLKGTIKRREKQFKEAAYKAASSEILLTEEAGFLEPEGIERTFKFTQNALRKEVDISTAHKMFSLDLKFGPYSIDYTRNGRHLLIGGRKGHVAAFDWQAGRLACELQLKETVRDVTWLHNETMFAVAQKKYVYIYDKTGMEIHCLRNHIEATKLDFLPYHFLLTSIGNTGYLKYQDTSTGQLVAEHRTKLGKCDVMTQNPFNAIMHLGHGNGTVTLWSPNMSTPLVKMQCHRGPVTAMAIGHSGSYMATAGLDGQLKLWDLRTYKAVQEYFTPSPASSLSISQRGLLAVGFGPHVSIWKDPFKTKQTSPYMNHLQPSSTIHNVDFVPFEDILGFGHGSGITSIVVPGAGEPNFDSLEANPFQTKKQRQEMEVHALLDKIQPEMITLDVDFVGKMDKAPIQVLNKEKKEAWAAANPEKATELKFKARGKNSSSRRHLRKKAKNVIDQKKVELLERIENDKKERAKRRAGDTDEAVTALDRFSGKKRKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVV7</accession>
    <name>A0A9P6MVV7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ammonium transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_010313</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ammonia transporter channel (TC 1.A.11.2) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000703">
        <property type="protein sequence ID" value="KAG0014669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVV7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008519">
        <property type="term" value="F:ammonium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3430.10:FF:000003">
        <property type="entry name" value="Ammonium transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3430.10">
        <property type="entry name" value="Ammonium transporter AmtB like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029020">
        <property type="entry name" value="Ammonium/urea_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001905">
        <property type="entry name" value="Ammonium_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018047">
        <property type="entry name" value="Ammonium_transpt_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024041">
        <property type="entry name" value="NH4_transpt_AmtB-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00836">
        <property type="entry name" value="amt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43029">
        <property type="entry name" value="AMMONIUM TRANSPORTER MEP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43029:SF10">
        <property type="entry name" value="AMMONIUM TRANSPORTER MEP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00909">
        <property type="entry name" value="Ammonium_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111352">
        <property type="entry name" value="Ammonium transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01219">
        <property type="entry name" value="AMMONIUM_TRANSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0924">Ammonia transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="18"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="179"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="207"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="237"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="265"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="288"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="321"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="367"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="Ammonium transporter AmtB-like" evidence="9">
        <location>
            <begin position="19"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0014669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="453" mass="47837" checksum="D7BB6254D8B64266" modified="2023-09-13" version="1">MNSTESGSTLAQYDAGDIAWTLTSTALVWLMIPGIGYFYSGMARSKNALSLIMLSCCSIAVVSFQWFLFGYSLAFSKSGGKIIGNFENAFFRGVLDQPSIGNPKIPDLVFMIFQCMFAALTPALAIGAAAERGRIVPTLVFIFLWSTFVYDFIACWTWSSNGWSFVMGGLDFAGGTPVHISSGAAALAYAIVLGKRSGDQKDFRPHSMSNVVIGTCFIWFGWFGFNGGSALSANLRAAMACVVTNLAASVGGITWVLLDYRHERKLSVLGFCSGAVAGLVAITPASGFVGPPASVAIGFLGAVACNMAVRLKVYLKYDDAFDVFAVHGVGGIVGNILTGIFAQASIAGLDGVTVINGGWLDGNWIQVGYQLADSTAGLSWSFVVTYIILVIMNKIPGLTLRADPSQEHTGLDIAELGEACYGHLDHKTVNTSIEVGEANSGVVSIGSSGEQKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MW88</accession>
    <name>A0A9P6MW88_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_009515</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000578">
        <property type="protein sequence ID" value="KAG0015974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MW88"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0015974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="107" mass="11486" checksum="E521C92FBD9DB98D" modified="2023-09-13" version="1">MIIPQTADESQVVQKRKRSIKTRSGSDDDGDDSDNVDGAKNLTGYCTEVKDNNIKTGDFTNVPSTDKDVTKDQTEQKKQSSPAGRTSCTIMGLSVFGTLAGTLIQLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWB8</accession>
    <name>A0A9P6MWB8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_010008</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the complex I NDUFA5 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000653">
        <property type="protein sequence ID" value="KAG0015164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWB8"/>
    <dbReference type="OrthoDB" id="286811at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006806">
        <property type="entry name" value="NDUFA5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12653:SF0">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12653">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 13 KD-B SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04716">
        <property type="entry name" value="ETC_C1_NDUFA5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0015164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="127" mass="14451" checksum="72D0BA841F2A9415" modified="2023-09-13" version="1">MFATRRLLSAVTKKTTGIYGLPVHPDPRPHLITIYGDTLKTLEKFPAHAVYRQATAALTNHRLNVVQSTEDIAKIEETLDAGQIEEVVVQAVDELKLAGKMLEWKAWEQLETPAPKDQWNYKFNEHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWN2</accession>
    <name>A0A9P6MWN2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HAD family phosphatase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_009815</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000620">
        <property type="protein sequence ID" value="KAG0015524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWN2"/>
    <dbReference type="OrthoDB" id="2012566at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02603">
        <property type="entry name" value="HAD_sEH-N_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="entry name" value="Putative phosphatase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43611">
        <property type="entry name" value="ALPHA-D-GLUCOSE 1-PHOSPHATE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43611:SF3">
        <property type="entry name" value="FLAVIN MONONUCLEOTIDE HYDROLASE 1, CHLOROPLATIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0015524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="208" mass="23666" checksum="7424C98688155B0C" modified="2023-09-13" version="1">MSIKNLIFDLGNVILRIDQDASANSLKALGATDFPTLARHHDITAIVDYEVGRISSAEFRTAIRSSTNLPDTVTDEEFDKAWNAMLLDFPEGRLEFVRSLKKDYGYKVYLLSNTNAIHIEYVDKICLKDYKEDSLNPFFDKIYYSHDIGCRKPSKEAFDHILKDQNLVASETLFLDDMLENVEAAKKCGLQAAQVDADTDLSFLHLRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWQ0</accession>
    <name>A0A9P6MWQ0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_009683</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000601">
        <property type="protein sequence ID" value="KAG0015724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWQ0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="517"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="517"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="540"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0015724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1247" mass="139134" checksum="D3B26309DBA439CF" modified="2023-09-13" version="1">MYQYGRGVIQDYSRAAEWFQWAANQGNADAQNNLGSMYKNGHGVTRDYTKAIHWYQNAASQGNSDAQNNLGSIYRDGCGVPKDYPKAIRWYQMAVSQGNADAENNIGVMYKYGHAVIQDYSQAVEWFEKAANQGNANAQNNLGLMFQHGHGVTQDHAKAVKLYQEAANQGHPEAQNNLGSMYETLDRSKAVELFQQAAAQGVVSALSNLGSMYQNGHGVLLDNSKAVDLYQKAASLGDADAQNNLGVMYYNGKGVTQDHSKAIELYREAASQGNASGQNNLGTMYYVGLGVAQDHYKAVELYRKAAMQGHADAQCNLGFMYLNGYGVARDHSKATEFYLKAAHQQHAEAQNKLGSLFRNGDGVPQDLGKAVEWYRKGASQGNAKAQHNLGIMYYNGKGVEKDISKAIDLWKMAAIQGNTSAQSKLEMVQRGDEKSKNPSHQSGEYVILWNDIKTVINNPLHLWDGETPVPFLKDKNSEFLQPLRIAEYLGTILDVVLKAPEIDTAMQSLMIRFLETGSSAKPTPSDNQQSLVMESGDPNTTATTDDSQAQAKRSQDCLKSCDDTQQINKGNYTGFSGDGRMDTQGIAKNAQRIEEYIQEAVADTQGVVADTQGAVADTQGAVADTQGAVADTQGAVEDTQTIEQDTPRVEERVVNINYGRGLAHYDGSYGAQQDFRLAAEYFLKAASQGHADAQHKLGLMYDRGQGVSQDYSKAAEWYRRAADQGHHDSQSSLGFLYESGLGVPMDLSKAVGWWEKAFTQRQTTYDKWERPETQAALAIRSGSIKSIKSRFGGAYQLLAKLAQSTSFGFPRLSVLQCGYLPASPTSLIKNLSYLPSIMSVIEVCPNLRMLELSFFDFRNESVLPKLLSLIRKKGRMLQELRIRKFACIRYKYLSSILWSCAAVERLTLDIDLYEIHRRFDRGNELELEAMAREALFGEVDSLSGLPSHLEIQDGKKSDTIAGSGLEFAWKELHMPFNTYYNVISLFTILRQCPHLESFTPPEIGSDITQEVLSILTASTLPRLKHLDLRYVDPSMIAGRSNIPQILDAFSGLKSVVFGTRVAMPIQTVQSLILRSFHSLENLTFVNSLSITTDGIHRILSSCPLLKRFDALVSLYREDTEISEPLEHNGDRRLDPTLILEPKNIGWVCYGLEILRLNYKNMDGELYIPVALRKQISMFRNLKDLRLQCTSYRENMTGEDGVIEALQEWSTLTDLRTLELRNFRPPLDKEELARIRQKWPKLEWIRFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MX00</accession>
    <name>A0A9P6MX00_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small ribosomal subunit protein mS41</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_009828</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mS41 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000623">
        <property type="protein sequence ID" value="KAG0015495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MX00"/>
    <dbReference type="OrthoDB" id="18595at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039603">
        <property type="entry name" value="Ribosomal_mS41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019083">
        <property type="entry name" value="SAM_Ribosomal_mS41"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28235">
        <property type="entry name" value="PROTEIN FYV4, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28235:SF1">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN MS41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09597">
        <property type="entry name" value="SAM_Ribosomal_mS41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01238">
        <property type="entry name" value="IGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Small ribosomal subunit protein mS41 SAM" evidence="5">
        <location>
            <begin position="38"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0015495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="110" mass="12539" checksum="94AC565E1949181A" modified="2023-09-13" version="1">MNSVFARCFSRVPSGIRCLHSGAVKKPIPAPRGDIQDPTTFLTKIGRNSVSFADKFKSWDHLFTATTAEMKSDMALSVKQRRWVLGWREKYRQGIDPYVIPVKPVKKKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXA4</accession>
    <name>A0A9P6MXA4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Mid2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_008394</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000453">
        <property type="protein sequence ID" value="KAG0017336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXA4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="190"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="272"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="351"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="415"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="526"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0017336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="584" mass="61144" checksum="F66279FD599914DA" modified="2023-09-13" version="1">MSTKFKKAVPAMLPFSLTVSSQSAVNSPGEAYLASVTFPSNYVISKIPIGCTSSSISSVSCTSLGKSRLMANFEDVYILGGTAGSAPKFESVVVNGEHCACQSSCPIFTSSLSLSTSIPTSTFISKSTFISRSTASTATSSTLTITTTAAASETTSISSCPTSSKGSTPTPTTTTTTLANKSSSKPNTGLIVGLTLTMILLVLLTAIYCFLRRRRQGLPFFLGVNLKGSKISLGRGGNDSGSQGVGVGQRASDIGNIESGYGHAVVGVVPAEKSHEGETQNPAQGPAPTETAEAVAQDQMSTGEPVDTTSTSVAAAAAAAATAATAAEAGSRSIVDPGATVIDIPELSESHRFSGNTQDDTVHSNNAASGVNDRQQTPADSLAAKSIESAPLIGAVESKHSRLYRAASGNLLLQSIRPPPHLTKDPAQNHQHRRARSYDSLPSGLLCNTFLFRSDSKTKTPSTPNRGVITTIRPEHHQQQMRQLQLEQDLEAENQRNQLSPREQAYLSFGKQSGIGLVSSMDAFINPGPPPLPPLSRARSNRNSKKGYTQPIHIRAQRDGASSSTAQEHAAKSEAHNPGLYGYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MY25</accession>
    <name>A0A9P6MY25_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_008747</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000485">
        <property type="protein sequence ID" value="KAG0016957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MY25"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19071">
        <property type="entry name" value="AKR_AKR1-5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827">
        <property type="entry name" value="2,5-DIKETO-D-GLUCONIC ACID REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827:SF13">
        <property type="entry name" value="ALDO_KETO REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00063">
        <property type="entry name" value="ALDOKETO_REDUCTASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="3">
        <location>
            <begin position="34"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Lowers pKa of active site Tyr" evidence="2">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0016957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="240" mass="26732" checksum="BF38FD3CBA11A7AB" modified="2023-09-13" version="1">MTRVNLSGLQSFCTLNNGRNIPLLGLGVYLIEAGKATEDAVLWALQIFVTTKLYDQDHGYDSALAACELSLQKLGLDYVDLYLIHSPNPGAERRAESWNALQKLVTLGKAKSIGKAYFYSITPMNLLNFKVHPWLARREIISFCESQNIAIEAYSPLSRGHKLQDPVVNKIAAKYSKSAAQVLIRWSLQKGHIVLPKSAKKERIEQNSEVFDFELADGDMEVLDSLDEGYVSGWDPTTAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYB5</accession>
    <name>A0A9P6MYB5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_008602</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000471">
        <property type="protein sequence ID" value="KAG0017117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYB5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="235"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="274"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="377"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="387"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0017117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="411" mass="45245" checksum="37704D44F57DCF94" modified="2023-09-13" version="1">MSVAAFPHEPIRRSNKHNDSRLEDHPIEVQELHLEPEPPAFHRLFVLTAIVIFLGAASSSVPNLLAARHPREQPSRASKGSSGIVSSAKASLGLTHDPAQHPQNSDIFTHIDSNPIPLLQKKEECEGLPAYGSLTSLSNIEKDKGNAAIKHTSEQCHDIPDYNTKEYTVRITSSAQTPPSPSSTINVIPIPLPDRGHEHNKPWKTPAVEEAKVRRLVQDCAWLSFQVTFWIIKRIYLAVVFVIAKPIGAAAAFAETPFVITRDICKAFLPVYSFFTVAAVVGITVGGFALWIAQLLIAAIGADREKKRKTIVLVQSNKNPYARSFEAEQKAGTRSDYHMDLNLSSANTVMGWETGVNSTRLRSKLNFGTPLGINVHRKRGAGVMPGGEDEDDGEDEYDEDDDDDDDDDEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYE8</accession>
    <name>A0A9P6MYE8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008163</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000435">
        <property type="protein sequence ID" value="KAG0017561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYE8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="324"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="406"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="520"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="706"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="840"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="432"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="520"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="721"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="859"/>
            <end position="869"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0017561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="886" mass="99222" checksum="59F8433A562D5DAC" modified="2023-09-13" version="1">MDTNSLSKASAMNIISTPSTNIPLGESAPPLSVRRDFSDPSTIVHDKGVGVSSPSVTRPDPPFKRWPDPTRSCSQRELTTGGNDAVFEKGSSRHAQRTKNKTRYFVRFADIQYDTDTADNKQSGASLNQAKKLTPARTVSEHSERNPTEPIGEFDFEDQPSESLHEGITADTSNRKARKRVSKIFKVVKQSWKDVWNDDEAEISNLRWIYKPETTISSDSPFYKVQLGVRFQDVVPERPAVFPYPSQIAYSSRYGSSVLPSDPSIAGGRPYLDDEARLRERLIRQALMRRKATGRFRRRPNITLPMTDGRTTQPVEVARIRRAYNDPNKHQQNNEGDKEQATPLEKMNRQARTGTVEWTVTRISPPEENTSTQSTSSARTETNVIKLPIQEHPLVSRRSLRRTVSTRFPDRPRNGGSPRIPRSVYMPKQKGNVDNMQTSSGVVTPSSGENIVTKLERVSTILYQSKGVSLLPKVVITSHQDIACESVSDTPATNELSDSISSLDATLLPPRPLFHYRDVEKETGDGPESHRNSGADRLSVDARMSRRSVYSNRSSVYSNRSASSNVSAVSSLANSVYSTLSEDWNRPTYYAKAISPRYPVSMQSKIKELPPLANFKILIKPKLVSAVETSSQMEFVTEVVRSRGLRHQNGDPIQIEKEDELYEVKYNISQEPLNDSTRQRGKDSLSPFTHLCKSAKPDLKDTLGFIDYGMQGSSSNSDGDNSVESDDNDDDIIERKVDILDVNDTSEMEKLSINPSDPHPNPEWFYNTQYEHFQEYGYFLDIPSEPVVENKVDEPSNAEQAHGALGFRKSTRKIISKSKKIMKGTFRTFQALVRGNLSDSSIHSTKGLKGDNVEIMDDTQPSYSANTRPDANGEGNIWTPRQLGGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYS1</accession>
    <name>A0A9P6MYS1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_006982</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000350">
        <property type="protein sequence ID" value="KAG0018600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYS1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="167"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="259"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="194"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="168"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0018600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="289" mass="31944" checksum="9D2342365864A9FB" modified="2023-09-13" version="1">MTKYQPLFDLHQLVQLTHSTTGKVIFYSQVNLAKDDNVDEDEAGGWVLSAFTGKTYFEREYRREDLDDLLITAGDKDWSSFAKRFKKAVLEGYFHIVDANPRECKVIIDNEVHSRMGSSSCTLETIEIDMYPVNHASRGEKMGEFMFECASYLQVRGCVLNPKAAGVNATSSGNKSHSAGTDADVGGSGKGKSYDDLKLERHNLKSENADLKKEIERLQAQVLKLGSMSSNGIGATSGRPKSKSAHMAMMVKEQLLKKRKGVSALNPRSKKGVLAKGTEFGSDDEEDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYW1</accession>
    <name>A0A9P6MYW1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">SAGA HAT/Core module component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">SGF29</name>
        <name evidence="7" type="ORF">BGZ80_008185</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000437">
        <property type="protein sequence ID" value="KAG0017531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYW1"/>
    <dbReference type="OrthoDB" id="10265994at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20393">
        <property type="entry name" value="Tudor_SGF29_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20394">
        <property type="entry name" value="Tudor_SGF29_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037802">
        <property type="entry name" value="SGF29"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010750">
        <property type="entry name" value="SGF29_tudor-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047288">
        <property type="entry name" value="Tudor_SGF29_rpt1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047287">
        <property type="entry name" value="Tudor_SGF29_rpt2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21539">
        <property type="entry name" value="SAGA-ASSOCIATED FACTOR 29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21539:SF0">
        <property type="entry name" value="SAGA-ASSOCIATED FACTOR 29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07039">
        <property type="entry name" value="SGF29_Tudor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51518">
        <property type="entry name" value="SGF29_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="SGF29 C-terminal" evidence="6">
        <location>
            <begin position="145"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="261"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0017531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="282" mass="31475" checksum="4EC7F2E7F2F4450C" modified="2023-09-13" version="1">MDRKNYRAGGTVGITPSAAASTNAVITGDDTQDEAVVWKRVLADLQRLSEIIDSNEGVITALDKVPEGRSNRSVTLCQEAAEKAREEGETIQRALEGVNLLMALRDGDLTNVDNTPEGKRKKRKIEAEGLISNSKKIRRYSSTDPNGIIPVGHQVAARTPKDKNKVEEWILARVLAYYADKNRYHVEDDEADENGEKMKYQLSARSVIMIADDQEDIPEFPAGHTVLALYPSTTCFYKAIVVQPPSKNKDYPTPLYRIKFDDDEGNERTAPPRMVLDMPKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZ22</accession>
    <name>A0A9P6MZ22_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">40S ribosomal protein S28</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RPS28A_2</name>
        <name evidence="4" type="ORF">BGZ80_008022</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eS28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000423">
        <property type="protein sequence ID" value="KAG0017689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZ22"/>
    <dbReference type="OrthoDB" id="10258930at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000028">
        <property type="term" value="P:ribosomal small subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04457">
        <property type="entry name" value="S1_S28E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000180">
        <property type="entry name" value="40S ribosomal protein S28e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000289">
        <property type="entry name" value="Ribosomal_eS28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028626">
        <property type="entry name" value="Ribosomal_eS28_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10769">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10769:SF3">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN ES28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01200">
        <property type="entry name" value="Ribosomal_S28e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00961">
        <property type="entry name" value="RIBOSOMAL_S28E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0017689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="71" mass="7944" checksum="B65196950C5C97FB" modified="2023-09-13" version="1">MDKTVVKHAKVTKVLGRTGSRGGVTQVKVELHEDPSNPSSVRHVIRNVKGPVREGDILCLMESEREARRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZ58</accession>
    <name>A0A9P6MZ58_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">tRNA (guanine-N(7)-)-methyltransferase</fullName>
            <ecNumber evidence="11">2.1.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Transfer RNA methyltransferase 8</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">tRNA (guanine(46)-N(7))-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">tRNA(m7G46)-methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11 12" type="primary">TRM8</name>
        <name evidence="12" type="ORF">BGZ80_005994</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>guanosine(46) in tRNA + S-adenosyl-L-methionine = N(7)-methylguanosine(46) in tRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42708"/>
            <dbReference type="Rhea" id="RHEA-COMP:10188"/>
            <dbReference type="Rhea" id="RHEA-COMP:10189"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74480"/>
            <dbReference type="EC" id="2.1.1.33"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="10 11">tRNA modification; N(7)-methylguanine-tRNA biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Forms a complex with TRM82.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.33" evidence="11"/>
    <dbReference type="EMBL" id="JAAAID010000296">
        <property type="protein sequence ID" value="KAG0019310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZ58"/>
    <dbReference type="OrthoDB" id="47276at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106143">
        <property type="term" value="C:tRNA (m7G46) methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008176">
        <property type="term" value="F:tRNA (guanine(46)-N7)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000060">
        <property type="entry name" value="tRNA (guanine-N(7)-)-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03055">
        <property type="entry name" value="tRNA_methyltr_TrmB_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025763">
        <property type="entry name" value="Trm8_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003358">
        <property type="entry name" value="tRNA_(Gua-N-7)_MeTrfase_Trmb"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00091">
        <property type="entry name" value="tRNA (guanosine(46)-N7)-methyltransferase TrmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23417">
        <property type="entry name" value="3-DEOXY-D-MANNO-OCTULOSONIC-ACID TRANSFERASE/TRNA GUANINE-N 7 - -METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23417:SF16">
        <property type="entry name" value="TRNA (GUANINE-N(7)-)-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02390">
        <property type="entry name" value="Methyltransf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51625">
        <property type="entry name" value="SAM_MT_TRMB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 11" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 11" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="3 11" id="KW-0820">tRNA-binding</keyword>
    <feature type="active site" evidence="11">
        <location>
            <position position="168"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="112"/>
            <end position="113"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="145"/>
            <end position="146"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="243"/>
            <end position="245"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00060552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0019310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="268" mass="30727" checksum="FEDCF3691CF1B6C1" modified="2023-09-13" version="1">MENTPTVAAGEKRQAEEIPAEVRLPQKKYFRQRAHANVFSDHHLDYPVSPAHMDWSKNFPKHFAPKDGEVVEGAVAVDSGKKVEFADIGCGYGGLLVALSTVFPETLMLGMEIRVKVEEYVNQKILALRNNHPGSYDNVSILRMNAMKFLPNFFEKHQLSKMFFLFPDPHFKKRKHKARIITPTLLSEYAYVLRPGGIIYTISDVKDLHLWMVKHLDAHPLFARIPDEELVDDPAVEHVRNATEEGQKVERNKGDKYLACYRRITDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZF0</accession>
    <name>A0A9P6MZF0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007217</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000366">
        <property type="protein sequence ID" value="KAG0018389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZF0"/>
    <dbReference type="OrthoDB" id="2437765at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="194"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="297"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="466"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="226"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="244"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="300"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="356"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="367"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="382"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="419"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="431"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="473"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="492"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0018389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="504" mass="55221" checksum="12F3303A34B92AF9" modified="2023-09-13" version="1">MAAPPAEIPLDSDDTAQTTANTFEASPEVILNRVNVKRTSTTSESEFVDRNDINEMAPSSAILHSDLPMNNAGTINDEIDVSEGVTLANSTQSSSPPAPKRVRYSNTKDGLTASDYAQLKPVIQPENNGITFSRSTPHCLSRKREIADLVHPSSQCSPVDMDEPEATIIYGEPVDSSSSTLSIEISEEEELFTPSLTTRYPGSSHITAGSPLSPKSPKEMEGRTKNINSRGSISSISHDDKQRPMPSMSASSSLFMPSHATRPRRNSCSTKKGFQRPVRIQLLDEAESDKIREEGRHLFPSSQSSSPSVSEHGLSWGQDQGQDQEADSGDMALRNGVDDEQSVALPIEDPIVHDWDMEELDDEESEGSATPSAEDSSASTENIKDRMTKGPGKELSHKLARIRKASISEAISVRGQDAVGEEEGDDDDDKWDPMLDPEREVSTMSEDQEAELYNIHMRLENQRDFQDASSLDLGERDGQSISEDGRYGGAIEADDEGEDFWENR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-06-18" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZT9</accession>
    <name>A0A9P6MZT9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA mismatch repair protein MSH3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2 6">DNA mismatch repair protein MSH3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_007059</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000355">
        <property type="protein sequence ID" value="KAG0018532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006409">
        <property type="term" value="P:tRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000870">
        <property type="entry name" value="MutS protein homolog 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1420.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051177">
        <property type="entry name" value="CIK-Related_Protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007861">
        <property type="entry name" value="DNA_mismatch_repair_MutS_clamp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007696">
        <property type="entry name" value="DNA_mismatch_repair_MutS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12984:SF3">
        <property type="entry name" value="N-TERMINAL KINASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12984">
        <property type="entry name" value="SCY1-RELATED S/T PROTEIN KINASE-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05192">
        <property type="entry name" value="MutS_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05190">
        <property type="entry name" value="MutS_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00533">
        <property type="entry name" value="MUTSd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="DNA repair protein MutS, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00486">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="709"/>
            <end position="985"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1260"/>
            <end position="1292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1309"/>
            <end position="1364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1403"/>
            <end position="1457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1475"/>
            <end position="1500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1518"/>
            <end position="1540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1277"/>
            <end position="1290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1320"/>
            <end position="1348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1424"/>
            <end position="1438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1475"/>
            <end position="1488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1518"/>
            <end position="1532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00019000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00073774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0018532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1540" mass="171133" checksum="A93B507E3F9E96A0" modified="2023-09-13" version="1">MIRQYIIKEGSSSLLLGIPTKYFCLAATAAVMHHIEETRHATFLNHSVQFKYQISNESMIIDCTTARNLELSTNLSSRNDKETLFGVLNETVTPMGARRLRCNILEPCKDEKTINTRLDCVEELSQVEETFYVLRTSLKAFNDVDHLITSFIQVPTKPSIKHSEQIINNIISLKHTLRSIAVVAEPLRTCQNKLLKTIYRILTDPRLAGFLNLIDNVIEQNVVQEKTAVGLRNQRCFAVKAGCNGLLDVARQTYKETINDIFEVVNRYVEEFNISLKVQFNTTMGYYLSTSVDQLEGGELPLIFINVVKKSKTMTFTTLELVKKNAKINDSLTEVYLMSDNIVNELSSDIRADIGAVYKASEALAMLDMLLSFAHLHMISDYVRPDFADTLVIKQGRHPVIEKLYSIPVVPNDTYAGPASTFQVITGPNMSGKSTYLRQVALLIIMAQIGSFIPAEYAAIRIIDQLFTRISNDDSIELNASTFTLEMKETAYIVQNVTERSIVIIDELGRGTSTHDGLGIAFAVCEELIHARALVFFATHFQELASSLMAYHNVVNLHLETEITRDNRDTPGIVYKYILTSGSAKEEHYGLSLAKTMNLSIDITDRAEQVSRELAELQEKACRQSESSRVIARRRTLSQIAHHIVLIQKSSKRLSRQKLTLVLQRAQQEAIAMMLAIRGRCNELDQAQIHLFFAHSLHPIQQVASASCMAYLSDFVKSTLSRVVLGKEIPSFPYTIGDRVDSFDSTIWALHKGIKREDNSQVSILCFDCVRQKDKLPLARNAFKKFRTIRHPDLIKYIDGVETESYIYIVTDAVTPLQDHLRADLDINLIRWGLYKVANVLKFLTVDASFIHGNVRTSSIFITKSGEWKVGGFELLSSLKEDQPAILTFAGLIPESNRYAPPEVRKKSWNVVKEYELWSTDTWHYACLIYEVFNGPFTSPEQLATPGKIPPDIGPFYKNLLRPDPKTRPSVGDFLDKGLQAKGFFQNDLIQVVLFLENFSVKEPLERDTFLRKLDLQVDRFPQEFCRYKVLPDLVHALEYGSGGAKVLPPIVKIGTMLDDQEYETLIGNILVKMFASTDRTIRLSLLENLGGFIERINKKVVNDKIFPSMALGFTDTAPIIREWTVKSVLLVINKLSDKVINYDLLRYLGKLQTDEEPGIRTNTVICLGKIAKHLNDATKGKILVPAFTRSLRDPFAHARVASLMALNATSESYDKNDIATRIIPCISLTLVDTEKIVRVQAMRSMDTFTKRIEKLVESMPDSAIVDTGRDSPNGPPRSTTPSTSSSSETWAGWAVSSITKKLATGDMQPQAVGSPQAGNSNAPSPTNTPAPAASSNGMSLSSSSAGLKVATESENGRRLGDGYSVNRYSSALAAVEADESASGGGWGNEDEGLFDNEGFEPMEEFEPSTSSPAPNLAPKHMTMSASRPSTSAGSSMSLGGGSTKGPSRLGFGAMDDGGTDAWDGDDDLFKSLNLSNNNNSGRPLSSSTTTAGGAIPASGFIRKEEKMAELARKREERRLRMAEAKERKKESSPLGAKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0T9</accession>
    <name>A0A9P6N0T9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005429</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000268">
        <property type="protein sequence ID" value="KAG0019670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0T9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040315288" evidence="1">
        <location>
            <begin position="23"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0019670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="141" mass="15923" checksum="0B9F0FC01420F3A2" modified="2023-09-13" version="1">MYARSLISIVLLALCAITTILASPAQQSNEFYVTSPKKNSVYHVGQEVPVKISIVNGTRGNLYRVNPSLTIYLQKDIPLPDLNVVVGNVRARTLYKNGYKFKVDKKYLIKQQSNVPFRIRASWETMERAGFADSAPFQLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1E6</accession>
    <name>A0A9P6N1E6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">GCS light chain</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Gamma-ECS regulatory subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Gamma-glutamylcysteine synthetase regulatory subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Glutamate--cysteine ligase modifier subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_002074</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heterodimer of a catalytic heavy chain and a regulatory light chain.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the aldo/keto reductase family. Glutamate--cysteine ligase light chain subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000150">
        <property type="protein sequence ID" value="KAG0021607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1E6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017109">
        <property type="term" value="C:glutamate-cysteine ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030234">
        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035226">
        <property type="term" value="F:glutamate-cysteine ligase catalytic subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006750">
        <property type="term" value="P:glutathione biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032963">
        <property type="entry name" value="Gclm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13295">
        <property type="entry name" value="GLUTAMATE CYSTEINE LIGASE REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13295:SF4">
        <property type="entry name" value="GLUTAMATE--CYSTEINE LIGASE REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0317">Glutathione biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="333"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="427"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="540"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="734"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="861"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="908"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="333"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="344"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="433"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="552"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="603"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="756"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="861"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="919"/>
            <end position="930"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00030406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0021607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="930" mass="99767" checksum="7F29325C89188DAF" modified="2023-09-13" version="1">MSAISTEAHSDLLNGQAYSNGNGQAYTQINGSNVTLPSFANQHFSHLTLYTGDTMRTGTTGQLNTNLKKSNQELVAAVEDTLLYSLNTAQIKGDSITITDETSLESLQGDRSSYEITGKSAKMFYLSPPSLAEAAGTPLSVEQLNVAIENLEAALGIPGIKLDHFILSLPNQAFDENGQDEAEVEAFTNEIQTLVLPVWKKLSELHQQGRIGRLGVAEFSKQQLEVLKKVVEAAAQEDGVVAVAPEVNQVNLQDCCVLPKDLISYTKENGIELLTHGDATNILPKETLTTLLKRHLPVAAESLVPNFVLKYSAFITSRGLIAKKGYIVNASSEEKTVETEMRKPSSSVSSKGRQQTEVSSKSDPSTAETTLNSKSVVAKPLSKQNPGTADSRPISGQAGLKPESSISKTCSTISDAKEARRLAAASTIVATAPQPTKNKASLNSYPESDEKKDNISKTRRNKHSTPIRPCDQPPNWRNSDKLLELISTSTVGPISVKPRADANSGLESRQNGQVISGANIDSFISTTTKRVHDVPIKVVADAKSPEQKGLGPSTNSTDATQKSAIRPKETPKNNATIAAQRDSSEERDDSPMPTTPPSNRKTIISSIAPSPSNSAPECSNSSRITGTMPVIPSERPRHNSVVATNHPTVILHPTVSTSLAAAHESCQRVDVMGLSDSEYQSGPPALGEKLNKSYADGCGIEASSEYVRAAVKAFVPRPDTVSTPPGVTKYLRTYPIPKSKPTREYNKVPLQSVHENSIDGERQQRSSTSERSERVPSFNSALPWDSVRPPETFQVTKPEATIPQAQSMDYTAQPSVTRVNTTYGSCTRSPLTPLGTNQASIPTTPIVKAASKTPPMAKAATASAKNASSPVHTTNKRPMVTVSPTNGKAANVTNAQALTDYESLDLKRPQKRTVRIPASSISRSENGISH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1Z9</accession>
    <name>A0A9P6N1Z9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Saccharopine dehydrogenase (NAD(+), L-glutamate-forming)</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_000862</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Amino-acid degradation; L-lysine degradation via saccharopine pathway; glutaryl-CoA from L-lysine: step 1/6.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid degradation; L-lysine degradation via saccharopine pathway; glutaryl-CoA from L-lysine: step 2/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">In the C-terminal section; belongs to the saccharopine dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000119">
        <property type="protein sequence ID" value="KAG0022172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1Z9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004753">
        <property type="term" value="F:saccharopine dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019878">
        <property type="term" value="P:lysine biosynthetic process via aminoadipic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12189">
        <property type="entry name" value="LKR_SDH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.360.10:FF:000008">
        <property type="entry name" value="Alpha-aminoadipic semialdehyde synthase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000087">
        <property type="entry name" value="alpha-aminoadipic semialdehyde synthase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000072">
        <property type="entry name" value="Saccharopine dehydrogenase [NADP(+), L-glutamate-forming]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1870.10">
        <property type="entry name" value="Domain 3, Saccharopine reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051168">
        <property type="entry name" value="AASS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007886">
        <property type="entry name" value="AlaDH/PNT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007698">
        <property type="entry name" value="AlaDH/PNT_NAD(H)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032095">
        <property type="entry name" value="Sacchrp_dh-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005097">
        <property type="entry name" value="Sacchrp_dh_NADP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11133:SF22">
        <property type="entry name" value="ALPHA-AMINOADIPIC SEMIALDEHYDE SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11133">
        <property type="entry name" value="SACCHAROPINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05222">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16653">
        <property type="entry name" value="Sacchrp_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03435">
        <property type="entry name" value="Sacchrp_dh_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01002">
        <property type="entry name" value="AlaDh_PNT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01003">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="6" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="3" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal" evidence="10">
        <location>
            <begin position="83"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding" evidence="9">
        <location>
            <begin position="253"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="18"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0022172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1010" mass="111257" checksum="22D771B206462FC1" modified="2023-09-13" version="1">MSSQASLATRALPRLGAVGRQLSSNTRRASARRHLSSSPVAMGETYFPASIQQHPQPSLSTLKQQQQYQKHTSASLNPYKSIAIRREGKNRWERRAALTPEAVEKLIKETGIKVYVQPSTKRIFSDDKYRAAGAIVQEDLSPADVILGIKEVPVKDLIPGKTYVYFSHTHKGQKYNMPMLQDVLDKKIRLIDYELMTDEQKHRLVLFGRHAGYAGIIDGVHGLGQRLLGLGYSSPFLHVGMAHNYKTLVSAKLALQSMGNTIMDEGTPKEFGPMTFTFTGGGNVSKGAQDVFKSLPCEFVDPKDLPKITSSKNTRLDRVYAAEVNIEDHIRHKTKNVFTSVEEYHAHPELFTSVFHKEIAPYSSMVINGAYWDARFPRLMSTEQLKAIQSDPANKFRMLSIADISCDINGSFEFMSHATSIEDPFFYVDAINGRDHKDTEAPGVQIMSVDILPSELPLESSQHFSNALYPFVKELIRGNNDHPVLAGATVAEGGSLKPTHEGLNKVLKETNAKENLAKLKASLGATGKTSFGSSIKPKKVLLCGSGFVAGPLVNYLLRDPNVSITIASNSQAEATSLALGKPNTTVVPLDVKDNDKMASLVKDSDIVVSFVPTPFHPIIAEHCINEKKNMVTASYISPAMKALDERAQRAGITIMNEIGLDPGIDHLSAMKMIDEVKAEGGKVTSFISWCGGLPAPEASNVPLSYKFSWSPRGVLTAGLNDAKFRMHNAFHEIPGKDLMKKHFPDVPIYPGFNLEGVANRDSLSYVDTYGLGPVEKMDTMFRGTLRYKGYADLMYSFNRLGLLNAESSQQNFSSWPEFMDSVLFGNNSSNTHDNKSRRAAIADRLDLPKNHASVDKVVDALQWLSLMPTSSGQAPFRAEGSTTALDSFCALLMNKLKYNPMERDMVILHHEFGVQLKDGSEQTRTSTLTSYGSFETYTAMAKTVGLPAAMATEMLLKGEIPEKGVLAPTLPHVYNPILEKLDREGVSVLEQIVQKGMRPTLKWGGSGVFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2Q5</accession>
    <name>A0A9P6N2Q5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">polynucleotide adenylyltransferase</fullName>
            <ecNumber evidence="5">2.7.7.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BGZ80_000270</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DNA polymerase type-B-like family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.19" evidence="5"/>
    <dbReference type="EMBL" id="JAAAID010000105">
        <property type="protein sequence ID" value="KAG0022431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990817">
        <property type="term" value="F:poly(A) RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010605">
        <property type="term" value="P:negative regulation of macromolecule metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031123">
        <property type="term" value="P:RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05402">
        <property type="entry name" value="NT_PAP_TUTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054708">
        <property type="entry name" value="MTPAP-like_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002058">
        <property type="entry name" value="PAP_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12271">
        <property type="entry name" value="POLY A POLYMERASE CID PAP -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12271:SF40">
        <property type="entry name" value="POLY(A) RNA POLYMERASE GLD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22600">
        <property type="entry name" value="MTPAP-like_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03828">
        <property type="entry name" value="PAP_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81631">
        <property type="entry name" value="PAP/OAS1 substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Poly(A) RNA polymerase mitochondrial-like central palm" evidence="13">
        <location>
            <begin position="1220"/>
            <end position="1352"/>
        </location>
    </feature>
    <feature type="domain" description="PAP-associated" evidence="12">
        <location>
            <begin position="1476"/>
            <end position="1515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="418"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="631"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1415"/>
            <end position="1439"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="1082"/>
            <end position="1182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="17"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="425"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="631"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="672"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="719"/>
            <end position="745"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF03828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF22600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0022431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1648" mass="187649" checksum="5323F87741533E0B" modified="2023-09-13" version="1">MNEGQYRSHIQGLHSTQQQQQQQQQQQQQQQQSELQNEIARAIHHARNEQHFSEFLFEIFLYELASAIPPNKTSTFVRFDVLQHSAYLAHSSMASYGEDPNSTNNVPGCLYEVFILTAPYAPTPEDVYLYLKDEWRVSRLFTREVIMDRTKTIPSQFPISCTVPRLTPQDHDHFQRVYSKIKPEFQDRYAAIVHTCRKYAWHIHGRKEDPIKVNGLWRIEKYTSKYNEELRKKWSIEEAAAAAAAAAAAVVAPTTNGVGSSSGAKTASASISAAISVSTPEPSEAMIPDSLLPLPPPVDERIEMDIINKKRICDDLVDYMGRSESRFDFVTRMAKWSAQHILLTNATMAFFNTMEARRVILLKRARQRAIIAASQRGEKKTRMEDRLKSVIHQSLEINVALDLSREAVETAKAKVIKKARRKEKRASAKKEKKQNQEGHRTNHKNIDAATRSWSERLEKAATAFRELSYFADEYTRLKSSMAPGIPYKNSGPHTLPPVRLAEERKDAMTLLTMLWNPSVPLRPTLVQFLDIAVRTRRISAVSSAQLLKFHDEVPIQEKENRPPLGGNRLMDSWIRDMSDGDWDKEVAANILDMCGSYDMYGDLIHVANCECSRHSEDDFYFDDDDSIDGFDDYDLDSESDYPNDYGRSRYSNMYSNESDEVPDLVSSGAEGNSDEVPDLVSSEAEEVPDLVSSEAEEVPDLVSSDDDMPAAESIIGNEMDERRAAKEAAERYARQEKATRVAVEKAEQAAREEARRAREEADRVAREKERMAREAARIAKEEAGRIAKEKADRVAKEEADRIAREEADRIAKEEADRIAKEQADRIAKVETERAAKEEAARVAREEAARIAKEKADRIAKEEAERAAKEEAARVAREEAARIAKEKADRIAKEQAERIAKQEQFLKESERFFQLEIEAIVQEMADRLVKEKAQDTQNTLTSINPVLHIQGTFRREMESQLASTKIEHENVRQLIIDIFTQKASVKSVLASAVEQRQIQSLIDKFKADGSQGIQSMRDDAKSIAEQQICLETWKEGSQSGQRYDMATIEGRFEQFKSVRQMKIAAIRCDAKVTADDSSIDVVCQSLEMQIKKLEEEEKRKRKALEKLEVLYEKLEAEIVEAIRAEEQRRKEAQRIAKEQQELEEKRRLEDQERLRLQQEAEEAARLKQEAEKEARALAAKQREPARLPTNGEVIYDWRGINLTLPMWIPPSNEQFNEMDAYITRWHQQLLPTQESINMRIEFLLRLQEMFDQEYPGEGLALKPFGSFVTGLGDISSDIDICVWCSDYQPYNDRYSIRSIASFLTRKSMQDVVAITDAKVPIVKFKDPVTGIACDMNVQYPLGIYNSDLIQTYLDIDARLGRLCFVLKCFAKCHGILDASLGYLSSYAYTMMAIAFLQDAQGQEGAGILPRLQLKNTQPRPYNEKGKPRSRPINFGNARSDGTVPEVHVRQEDKVYDCTFDNRTSLYKSYGYMNKKTVAQLLFEFFQFYTRKFDYRSMEVSAKMGRTQERHSLMKEKALRASVDLSTSRRHQYSYDSKRNIWVSPSERAYFKDLDDNGGVPSGNVPVPGSSASTSTTPVVVTTSGQGNPFGAEAFLCVMDPFIVGRNVAASCRGERLVKVWKCFDHAYKCIALGNFEEAFKPIASNDTQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2X4</accession>
    <name>A0A9P6N2X4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Arm-like repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_001682</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000139">
        <property type="protein sequence ID" value="KAG0021803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.80">
        <property type="entry name" value="E3 ubiquitin-protein ligase SopA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056251">
        <property type="entry name" value="Arm_rpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848:SF8">
        <property type="entry name" value="F-BOX AND WD REPEAT DOMAIN CONTAINING 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23948">
        <property type="entry name" value="ARM_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141571">
        <property type="entry name" value="Pentapeptide repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Arm-like repeat" evidence="4">
        <location>
            <begin position="276"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1281"/>
            <end position="1322"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1323"/>
            <end position="1364"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1365"/>
            <end position="1406"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1407"/>
            <end position="1448"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1449"/>
            <end position="1490"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1491"/>
            <end position="1532"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1533"/>
            <end position="1574"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1575"/>
            <end position="1616"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1617"/>
            <end position="1658"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1659"/>
            <end position="1700"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1701"/>
            <end position="1742"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1743"/>
            <end position="1784"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF23948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0021803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1875" mass="209279" checksum="F76B3B3D1481F8B6" modified="2023-09-13" version="1">MLRNPFSSSKSKLSLNDALGLANEALENARRAKTNPAEALQFCNDARSRIKDAENIISTKKSRDPTLSDSIANAYHEHGKLLDELGHRDKALKSHSKAEKWGYVPAISQHTDSLQPANTGESIYQSTSPTTSFSASPSMIAMHQGVSEAPHLGHQGSPQDVVLTEVDIETSAPGESSMTGAIYQDTPRISHLDLQQNSQDVIPTIVGNNASTLKEDVELIPQNYFEQNVTPPVAKYALPDIGGRVNSTPQLAYCLSLLNPSLASREQLNESERSWLQARADDPDERKQLEAMATDLVRAFVRDELKKPNVVAEVVSLAAVFEQDDFRKLLQVFVDNINQSVLLKVHLIDGLAQLIRNAAQGHIDGDDLVKILELLNARLKDTHEQSVQHIYRLARAISQVLDSMVDSQVEGLSREQLHEPLSDYLKGLQKSSDPYLVYQAAYAYQALLHIPDDESILQSMMRRTGKLVQGISGVVSAVKALDLTGFIEGLQSIQNGLASAEKVIELVSDAYGNAKDLAESGQELLESLKEGFSFTRKSTWYPALRGLDSLLQEGRFAEFEKLVQEAPCRNNPAFQWGVCQWLGEIASNSVWGLKIRICAVSFLMGLYRNNSRWACQPYIKQWILRLLDQSAQSLQGIIADDAWALLQEIQGIGSADKLTPYQGSEEYNAIPYPTMFTSPPQESPLLSRVQDKPDVESSLRQLKRERLQDRGGDIYISPRAKANPRATDDFDLASRVQEFLESKRKVFLVLGDSGTGKSTFNRALEISLWDKYNTDGRIPLFISLPTIEKPERDLVAERLRQANFTESQIRELKLHREFILICDGYDEIQETRNLYRSNQFNQTGGWRVQMLITCRTEYNGADYRDCFQPTERNIGGDSELFQEATIMPFNEGQIQDYIVQYVSLRKPTWGCDDYQQALKQIRNLRDLVKNPFLLKLALEVLPRMFSTNSQFSTARITRLHLYDEFVAQWIERGKIRLREIDLSSRDKEAFKEMEDLGFGEHGIAYLKELVTAIYDNQSGNPVVNYLEYRDRKTWKEEFFSDRDGKNLLREAIPLARNGDQYQFIHKSVQEYGMALAVYDPSDHNEDAEPVPVVSRRGSTSSALSFELPSTESAAAVNENSLLNSPLGKRNLVGEQSILRFLSERVQQQPVFKDQLHSLIKQSKTDESVRTAAANAITILVLAGVQFNNADLRDIKIPGADLSFGVFDSARKVNLQNIWMRQANLREARMKGVHFGELPFIREDDNVCCCAFSPDGKTLAVGLSNNNIKLYETSSWDRIRTLKGHTNRVWSLSFSVTGNRIVSGSQDKTMRLWDIDTGDCVRTFLGHTGAVYSVAYSPKGNRIASGSHDKTVRLWDDDTGSCIFTLQGHSEYVKSATFSPNGEWIASGSKDTTVRLWDVDTGSCVRTLLGHADFVNSVAYSPKGDRLASGSNDKTVRLWDVDTGDCVRTLQGHTDSINCVAYSPKGDQIASGGSDKAARLWDVDTGECFSTFRGHGHSILSVAYSPKGDQIASGGLDEKVRLWDAGAPEYAYTLQSHSNKVYSVALSPKGDQIASGSNDRTIRLWDVDAGSCVRTLRGHNGAINSVTYSPNGNQVASGSTDMTVRLWDVNTGECLNIFQGHTTWVQSVVYSPNGDWVASGSDDRTVQLWGVDTGKNIKTLLGHTGEIRSIAVSPKGDQIASGGEDTTVRLWDVETTHCLYTLQGHTSRVLRIVYSPKGDRIASGSIDRTVRVWDPDTGNCVHTLRGHTSIVYSVAFSPSGDWIVSGSDDITIRFWSVETGQCLLDISSFGGCVYSIDWSDTSDDQYFVTGSYDKSVRRWRFVKDKDEYKAILCWNSPHESLAVHGISFEDVQDLSRQNRELLNQRKNITMYLSILE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2Z2</accession>
    <name>A0A9P6N2Z2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Dodecenoyl-CoA isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ECI1</name>
        <name evidence="1" type="ORF">BGZ80_001563</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000136">
        <property type="protein sequence ID" value="KAG0021855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N2Z2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941:SF45">
        <property type="entry name" value="ENOYL-COA DELTA ISOMERASE 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941">
        <property type="entry name" value="ENOYL-COA HYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0021855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="307" mass="34258" checksum="B111845D8C5F5558" modified="2023-09-13" version="1">MQSTRFTTLFSRTAAAAAGRQSMQRSLTVPITRPVVIRTFTSATDTPPAITVSKDENSPEVAIVTLHQSAFSHETAKLFLKEWKAMEQDQSIRAAMLKSDLKSIFCAGIDFQEFLKGPESFASYWRTIRHVFDAIYSSRLNTAASMHGHSLGLGCVLGMACHDRFMMGAVPKPGTIGLNEVAVGVPVPHWLAELFASITSRRSAERFLPLGRILSVQEANSIQLVDKIDFKSQQEMDEFVIRYLAGRSKSPRVAQAETMSVIRQSFLKMFRESEEYDIQNITKYVSEPEAQTILKEQVAKLASKSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N305</accession>
    <name>A0A9P6N305_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_011236</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000088">
        <property type="protein sequence ID" value="KAG0022756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N305"/>
    <dbReference type="OrthoDB" id="2417267at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="25"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="98"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="277"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="391"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="465"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="722"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="231"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="98"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="421"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="482"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="574"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="613"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="638"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="726"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="738"/>
            <end position="775"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0022756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="775" mass="87314" checksum="5E41D84FB3AA6234" modified="2023-09-13" version="1">MTFDSQMTVIKHNLDPYGKYYGPSQSNGFSLHPTPEPTASPLATSSIRPGPRERTNFLHEQGNIPRRVPTSGPGWMSPNRRSRSQISAVLRARPSSLPLMSSRSLSQQPQHQHRVETSSSQSIFSLPGMQQLQNRLLQLAEQQRQQQQLATPPIRPRQAFSESEIFLPPLPRQTEMIGTEDHYEGDHMTSTAPLIQESHNLISGKQSLQIERGMNLDSPFFTDVHTEVRENMNTSEANLQMEQELEEVRRAIEEASDRYNEAVQKLRHAKEREQALMFEQDRRMYSGGADYEPGSDEESLTEHPSLYSKDSSRDPSAYEQFPLFPPTDLPYQYQHIQQRQQLQNYSQQRLRPLASPVLGREFIQPHENRASPLQARKLDLQMGERQRSVTVVLQSGDAVSGREPSLPREQRTAQPSACQENSNASGSSSSGNSGSDRNNNIGGDAHEKAKELLQQYLSSPRIKIKSEESESKPSIHGSAASSKKEPEDDPGESRQRDWYKEYKEYSIPIEIPSSETDASSEADRMGASTSQTGGAEATFRGKHSVRWRPPTPVPAKVNSQYKKERHPPVLPTIGATSEYNGTDISRRPYRRAHLSGPRSGRSYIPLPRPYPPQTSSRVTSTSPLPQAPSQIPSSRTTPQRRHRHGGQRSQTRPRIRVASSSTGSLGPRFSEFLNAINAEPELQQQVTGSQGHRMIVFYTNIERVKTNIERVEHYHHYYSKKPPCAHTSSCASQQDASLDMEEDIEAESESMEEDEGSEREVESEVGDEQMEDCSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3A4</accession>
    <name>A0A9P6N3A4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nuclear pore protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_000906</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus envelope</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
            <location evidence="4">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the nucleoporin interacting component (NIC) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000120">
        <property type="protein sequence ID" value="KAG0022151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3A4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016973">
        <property type="term" value="P:poly(A)+ mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007231">
        <property type="entry name" value="Nucleoporin_int_Nup93/Nic96"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11225:SF4">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP93"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11225">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP93 NUCLEOPORIN NUP93 DEAD EYE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04097">
        <property type="entry name" value="Nic96"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="4" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0811">Translocation</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="924"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="934"/>
            <end position="943"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="944"/>
            <end position="953"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="954"/>
            <end position="963"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0022151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="994" mass="112158" checksum="83B28644D2247438" modified="2023-09-13" version="1">MSFSTLAQLAEQSKQLTSHIGGLQLPHIERGIDQIENQSRKLAAKASKPVDVGDNKAHFFLAKGGVDANAINNTLSSINLSTFEPYQPIHDTDTEAFLRYQHEQIIVNTIDESRRETVMDFDSNFETSLNYDWERTKKRIFEELGHHQGRGSGSDKDLGQSMGSFRGSSSLGFSQNSTHLPGFNQNPASPDIIYSKLKPYYKVVYDLCDSRLQGTAFPLTTNFVEASRLAHKDQPNPKIQETWELLVSILGEQELFNGRFQSKTLKERAYADAYLGSPVKSPAAAILRERLIKGSKVFLERQFMNHIEASVAANPAEANLGGVPSLLNTVRAFVQLKYLRYGSWSQPNLEITNGQAMWAQIYYLLRTGHGHEALKFANENEASFGPADRQFVTYLAAYLESEDRTLPTPMQERLLSDFNQRIRYSSDTVDPYKLTLYKIVGRCELNKRTTPVVGALEDFIWLQLSMIREPKNDTMPQDKYGLSDFQALVLKYGPNYFNPNNNNPLQYFQVLLYSQQFERAIHYLSSFRAYTLETVHMAIALTYYGLLRIPSVHRVSDPNPFSTTTDALGNEVSHFNFTQLIHYQARIIAEHYPTEALTYLYQICLNTDLTPDINKEQISLCHSYIQELVLQAKDYSALLGTTRHGIKAPGVIEKYLPLIKIVNSSQFVKDITIEAAKSKSNEGRVEDAIQLYSIAEAYNQVVELLNRQLAEAISNPGLQSVGESGINIPAIRRLINEYVSDPKVNQQIVPKNLETCSILLKLVEFTEYYDRAKYEAAVSVIVELDLIPLEADMSVIAKKADQFQGLDECVARNFPDVLLKTMESLYKLYQTLKMSPYDEAGRRDNINMLKRRARHLRAGWMAQELLLTFGNTIGELALIPGKSATFIVRVNGEVVFDRADHKRFPEMKEVKQLVRGVIAPEMSLGHSDSAVKSAEADKKKEQEATPTSPPEVSQQQQQQQQQQPEGSQKACNVSSVDVDDEDSTTHSFDCKTCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3W6</accession>
    <name>A0A9P6N3W6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial</fullName>
            <ecNumber evidence="5">1.1.1.41</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Isocitric dehydrogenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">NAD(+)-specific ICDH</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">IDH1_4</name>
        <name evidence="13" type="ORF">BGZ80_008472</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-threo-isocitrate + NAD(+) = 2-oxoglutarate + CO2 + NADH</text>
            <dbReference type="Rhea" id="RHEA:23632"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.41"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">Octamer of two non-identical subunits IDH1 and IDH2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the isocitrate and isopropylmalate dehydrogenases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.41" evidence="5"/>
    <dbReference type="EMBL" id="JAAAID010000046">
        <property type="protein sequence ID" value="KAG0023701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3W6"/>
    <dbReference type="OrthoDB" id="10261637at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004449">
        <property type="term" value="F:isocitrate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006102">
        <property type="term" value="P:isocitrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.718.10:FF:000001">
        <property type="entry name" value="Isocitrate dehydrogenase [NAD] subunit, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.718.10">
        <property type="entry name" value="Isopropylmalate Dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019818">
        <property type="entry name" value="IsoCit/isopropylmalate_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004434">
        <property type="entry name" value="Isocitrate_DH_NAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00175">
        <property type="entry name" value="mito_nad_idh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11835">
        <property type="entry name" value="DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11835:SF42">
        <property type="entry name" value="ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT BETA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53659">
        <property type="entry name" value="Isocitrate/Isopropylmalate dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00470">
        <property type="entry name" value="IDH_IMDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="6" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Isopropylmalate dehydrogenase-like" evidence="12">
        <location>
            <begin position="45"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00071938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0023701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="375" mass="40731" checksum="9BF5669755517D6B" modified="2023-09-13" version="1">MLRSLTLSKPLAATLNKMGPRAMSTSTITSQHQDYPNSKLGGRYTVTLIPGDGVGQETAAAVKTIFKAANVPVDWEQFDVSGYTSADDNTFKQSVESLRRNKVGLKGILYTPVSSLGHSSFNVTLRKDLDMYASLVLCKNIPGYPTRHQGVDFAIIRENTEGEYSGLEHQSYPGVVESLKVITRTKSERIARFAFDFALRNNRKKVTCIHKANIMKLADGLFLNTCREVSKEYASSGIKFDDMIVDNTSMQLVSRPQQFDVMVMPNLYGNIVSNVGAGLVGGPGIVPGCNIGREYAMFEPGCRHVGKDIQGRNAANPSAMILSSVMMLRHLGLDDHANKIANAVSKTIMGGAVKTPDMGGSSTTTDFTFAVISNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4A8</accession>
    <name>A0A9P6N4A8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">squalene synthase</fullName>
            <ecNumber evidence="4">2.5.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">ERG9</name>
        <name evidence="16" type="ORF">BGZ80_009675</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the phytoene/squalene synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.21" evidence="4"/>
    <dbReference type="EMBL" id="JAAAID010000060">
        <property type="protein sequence ID" value="KAG0023363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N4A8"/>
    <dbReference type="OrthoDB" id="431150at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051996">
        <property type="term" value="F:squalene synthase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006696">
        <property type="term" value="P:ergosterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045338">
        <property type="term" value="P:farnesyl diphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00683">
        <property type="entry name" value="Trans_IPPS_HH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.600.10:FF:000003">
        <property type="entry name" value="Farnesyl-diphosphate farnesyltransferase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002060">
        <property type="entry name" value="Squ/phyt_synthse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006449">
        <property type="entry name" value="Squal_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019845">
        <property type="entry name" value="Squalene/phytoene_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044844">
        <property type="entry name" value="Trans_IPPS_euk-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033904">
        <property type="entry name" value="Trans_IPPS_HH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01559">
        <property type="entry name" value="squal_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11626">
        <property type="entry name" value="FARNESYL-DIPHOSPHATE FARNESYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11626:SF2">
        <property type="entry name" value="SQUALENE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00494">
        <property type="entry name" value="SQS_PSY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00005">
        <property type="entry name" value="Isoprenoid_Synthase_Type_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01018">
        <property type="entry name" value="Squalene/Phytoene_Synthase_Lik"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01045">
        <property type="entry name" value="SQUALEN_PHYTOEN_SYN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="14" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="10" id="KW-0756">Sterol biosynthesis</keyword>
    <keyword evidence="13" id="KW-1207">Sterol metabolism</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="15">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040329374" description="squalene synthase" evidence="15">
        <location>
            <begin position="18"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0023363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="416" mass="46955" checksum="A8DA0741EDAED87A" modified="2023-09-13" version="1">MASAILASLLHPSEVLALVQYKLAPKTKYDYSNNKTRERLYHHLNMTSRSFAAVIQDLDDELKDAICLFYLVLRGLDTIEDDMTIDLEIKLPYLKTFHEIIYQKGWNFTENGPNEKDRQLLVEFDTVIEGFLELKPAYQTIIADITKRMGNGMAHYATAGINVVTNADYDEYCHYVAGLVGLGLSEMFTASGFESPMVAERKDLSNSMGLFLQKTNITRDFLEDLRDNRRFWPEEIWGKYVDEIKDLTEPENKEKALQCLSHMVVNAMAHIRDVLEYLSMIKNKSCFKFCAIPQVMAIATLNLLHTNYMIYTHENVKIRKGETVWLMKESSNVDSVAAIFRLYARQINNKSNPLDPHFVDIGVICGEIEQICVSKYPGSTAELHRLQAGVMAGTSGNVLTAAAVVAGAIALKNVIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4L4</accession>
    <name>A0A9P6N4L4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">GTPase-activating protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">GYP5_3</name>
        <name evidence="6" type="ORF">BGZ80_009460</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000057">
        <property type="protein sequence ID" value="KAG0023421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N4L4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.750:FF:000003">
        <property type="entry name" value="GTPase activating protein (Evi5)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.80:FF:000027">
        <property type="entry name" value="GTPase activating protein (Evi5)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.270:FF:000001">
        <property type="entry name" value="TBC1 domain family member 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.750">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050302">
        <property type="entry name" value="Rab_GAP_TBC_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219">
        <property type="entry name" value="RAB GTPASE-ACTIVATING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219:SF22">
        <property type="entry name" value="RAB-GAP TBC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23436">
        <property type="entry name" value="RabGap-TBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="5">
        <location>
            <begin position="618"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="478"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="866"/>
            <end position="1016"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="66"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="86"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="132"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="172"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="203"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="245"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="300"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="316"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="350"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="417"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="438"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="496"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0023421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1020" mass="112941" checksum="CB31B2EC193911C9" modified="2023-09-13" version="1">MMVNQHSSFAPQDDQDYDLIDGYGATSDAEPNSGHGHLQTRGSFAKAANQSFEEAAPIKNSRNSWEENDSDDDPYPADSYTYGRDDSDDDDADDNSDEEEHKEDSHNASNRESQRKAIGTFDQGSDDERPQNRNLFRTSSSNPRASINSNRSYSSHTKHHSFGYGDDRPEPSESESNSESESDQDETFIDAPLASAPFIPSVSRPSSIQSASNTFSKPGSPTLTRSAVAGTSSIEPESKKANDLTASSPPTPSSATATATPLPINSTNITSPAAKVEAQLPEQARPLLPNTSDQAPGRASGSESDNSNSSNSHRSPLTNSHSRNTSRSGIFPRSISTNAVSSRGPVNGLLNAQNRGSSYSDLSDAELNEVSLDDNSAPGTPRRSFGSTVATPRAPVAASNAGFPSSFFGGKPHPKSQQFQQQQQQQSGVISPRPLASATATPLLQSPVTSTPETRPNGVLNGSISSIASSIQGAFMGRGFGGSSNSALPPPPPVRTPSGSSSTRPSLTSMRITTNNVGIDLRSSNNISPERASTFSTMTTDSNMDLLLARLEAENSMLEQDTKRRLTTDSEMDRALGHAKEESPEEDVDWDYWGALMHDYNGVVKKNPKQLTQMIQKGIPPALRGLIWQLLAKSKDAQLEATYAELLKSTSTHEKQINRDMNRTFPNHEYFQAEGLGQESMFNVVKAYSLYDKEVGYCQGLSFVVGPLLLNMPDEEAFCVLVRMMTTYDMRGHYTPEMNMLQLRLFQFEQLMEETVPMIHRHFQNQGIRSTMYASQWFMTLFAYKFPLDLVFRIYDILFVEGVESLLRFGVALLKANQEQILNHDFETLVEYLKNGLFEHYKDNPSLFVQDAYNVKVTPRKLAQYAQKYNNMIQKQQAELAAEESLRETNRQLSMQVRRLESSLHTLNKEHVDLAKELIARKLDMANLQDQNDVLTQKVSDLTKIVDSQAKEVEDRLKDDIQSVMQKNMELTRKNEEVEDQCSLLESLLIETKMKYAESENERDNLARKLADLRKALGAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N7S8</accession>
    <name>A0A9P6N7S8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_000010</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000001">
        <property type="protein sequence ID" value="KAG0024882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N7S8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF5">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="7">
        <location>
            <begin position="235"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="47"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="323"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="592"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="675"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="752"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1046"/>
            <end position="1128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1180"/>
            <end position="1209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="53"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="344"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="358"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="675"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="752"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="764"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="791"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="830"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1065"/>
            <end position="1091"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1182"/>
            <end position="1200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0024882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1209" mass="134514" checksum="F12C7FBE9CE86146" modified="2023-09-13" version="1">MKKRGPRQGYIELLEKRLDKMEQMLQHGPAAVDPELLDSKAILNSGLRPGNRRSLSPTAEGQSDSNADPDERYLGTTSGYSLRYNDYDKLNTHGNQLIGSKDSLPSTLTLKDRPKNPIYGIKDEIPRKDILDHLIDLFFDSIYFQIPIIHPGTFMKQYKEGKVSPNLLNAMCAAVARFSNHPDVVTTPAFLAGEPFATNVRGMVVDSIDTPTVSNVQALVFLSMYEYGAARGPRAWMFGGMAVRQAQELGLNREDSSPVFHLKGDWVMRETRRRTFWACFMLDVLASSSSGRPKMMDERDCEVLLPSEDHDWCDERPVVTEMLDDGEDSSSGTEREGSTTPKKTHQEKQAGAAEKDAAQSTDTNETSASSKKQWDGHVLSSFAYLLRIVAILGKVSQYVNRPRSKKAIPPNQRGSEFSVIDSALTAWHKSIPPNLAYSLENGKMIKDKGEGCIIVFMHVIYYTAVVLLHRPILAADKAAFPLDSSFVENSVTRCADAANKVSDVLEFVQAYNCPPRIYISSFFAYPVFTTATIHITNAFASDPDVAARARRSLSVHVRVLQTMKSYWSMADKFFYIIRDLYSIQSKISSTAHLSKQSHRNTQDQPTITAGRVEGSSEESGTLTRLEADGAESSKPSASNATGLSGKLASISSFLKSDSGLIALWRRATEMQVLDEAKQEQRQRSTSEEIAKQSPKLEKSEYAIQDRALQEHRKRMNELEIQQINQEFDRQWKSKMNEPALSFGKGLIEESVKPHTVHGGDKGNKIQQDSASLSSEKRQIEDDPANPRVTKQVKTTRASPKPSNSTDQNVHEQFLSDMPPNPDRSESTPLSNNMSASSRSSGEHSSVRPTTYRHSVVQKPQELQHQESYILQPMQIQPTIESSAGVTATSADVNSGDVNRHLMGVHSPQHRQHDTFPRSINMIQNTNIQRQQRQLQLQQEQAAQMSSLAFGPSSSFTPPYLQHASLQSQQGFSSQGQMSGTIFGLPLVYGSNYDTSQAQRVQTESLGSLFDFALPQDDISFLSNSFQATPTMMQENMGFANIKSGPVPTSTGPMGDEMRNAADAGSNISGTSLDSQSPNLDPNNPFNISSRLHSFLMSEEPYNGNTTSGHNSGHGGNDGGLNSMGNGVQATPTNLIRYLQHHHQQELHQQELRQQRNMQPVLNQQNSLIFDDFFPWNHFSVGQQQQQQQQQQQQQQQQQQQAPSSQHQSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SRP4</accession>
    <name>A0A9P6SRP4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007961</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004189">
        <property type="protein sequence ID" value="KAF9993969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SRP4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9993969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="69" mass="7173" checksum="56A594F46B108ADD" modified="2023-09-13" version="1" fragment="single">HGKLPTLDMTVVDVAQKHEKVDVHANGDGKNTKSSGPSSSEVKLNKAGAFAYGGSLKNKGIKLGLVTIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SSB4</accession>
    <name>A0A9P6SSB4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007321</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003723">
        <property type="protein sequence ID" value="KAF9996188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SSB4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="130"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9996188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="298" mass="32098" checksum="E58BE709DC48D123" modified="2023-09-13" version="1" fragment="single">MDRSMKIGDQLHAIQLPEFHLPDLQRLKQQLNKHTPSFSLKSLQHSFNVPSYTSYTSYTPSFSPSPASSSSSTTTTSSSSSIASSASPIATPDPAKSRLSFASRLSLSSTAGLNGKNSKRKSDEKIPNVTAASQKPTTATSTATATATSTSTAMVSSEETLHASLPISIPTHPSNYLIKKQSAVPEPDSSLTSGTHIVPKPSETKPVSASKSPVGHLFLQIIEARNLTLVNPPAMSWPYCLVEYDQNELITPPALQETDSMGRRGGNDIFARAMAASSPKWRHDVELYVLLLFLNRIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SSI8</accession>
    <name>A0A9P6SSI8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_006991</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003501">
        <property type="protein sequence ID" value="KAF9997521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SSI8"/>
    <dbReference type="OrthoDB" id="2345144at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9997521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="425" mass="49091" checksum="6C19F8EBE7BB80C4" modified="2023-09-13" version="1">MIESLTLNFQENIEFGQKPNNFGEEEKQEEEKYPGIEQTDVFVEILQSCPFYRLRSFEIRGLHPHTLSRPYLYECGTSAMWRQFSLGLQEVRDQAVARIIEAAVIAATAEPNPLPNNSTIDTNVRSRGIRRLTISDSTSFRKLSLQMITDTSLSTTLEELDVQRCGYFRSEEMHFVLSRLPNLRVADFRCRDKMAVLSPYSGLLPKKLSYEEELKYGYTSPPSSPAGTEDDIPVIPPRIWACCGSLRSLRIGVTNASIERYTDGHYYRGFEMWIRGAEIYWIRDHPETRKPYPEALHWFFDQIATLTQLKELCLVTVEPEYHTTRSLEISLKAGLDRWSTLRDLECLDVEELDHSIGLEDVKWMVDNWPALRTIRGLIHETDMFLSEAVIWLRNARPDIELPVSTVVPRMNAVQAMNYYGDDDDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6STM3</accession>
    <name>A0A9P6STM3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006245</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003077">
        <property type="protein sequence ID" value="KAG0001044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6STM3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31389">
        <property type="entry name" value="LD39211P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31389:SF4">
        <property type="entry name" value="LD39211P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0001044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="256" mass="29164" checksum="DC8239913650362D" modified="2023-09-13" version="1" fragment="single">MSTFVIIWLGWSSFRLKDSNYSSGTPSTPLRNAGSSINNQYINPHEGESEHDLPSVTDRTTSVLENLHKPFTIVTAASSNHFCALESFLYSLSEILDGLERTEMRPTIVVYNLGGMTPEQMTQMEWLKDNQYMDEYKDFEYSKYPDFWDITVARGEYGWKAGIIKEVADKYRGLLLWLDSGNMLALDFLRYLPGYLDKYGFWSPKSSGTFQQYTHPGLPQFYGDSLENYIGETNCNGAAIAFDASNDNIYNGILKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SUM5</accession>
    <name>A0A9P6SUM5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">aminodeoxychorismate synthase</fullName>
            <ecNumber evidence="4">2.6.1.85</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Para-aminobenzoate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">p-aminobenzoic acid synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BGZ80_005461</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>chorismate + L-glutamine = 4-amino-4-deoxychorismate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:11672"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58406"/>
            <dbReference type="EC" id="2.6.1.85"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 4-aminobenzoate from chorismate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the C-terminal section; belongs to the anthranilate synthase component I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.85" evidence="4"/>
    <dbReference type="EMBL" id="JAAAID010002693">
        <property type="protein sequence ID" value="KAG0005339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SUM5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046820">
        <property type="term" value="F:4-amino-4-deoxychorismate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008153">
        <property type="term" value="P:4-aminobenzoate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:L-tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01743">
        <property type="entry name" value="GATase1_Anthranilate_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.120.10">
        <property type="entry name" value="Anthranilate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005801">
        <property type="entry name" value="ADC_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019999">
        <property type="entry name" value="Anth_synth_I-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006805">
        <property type="entry name" value="Anth_synth_I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015890">
        <property type="entry name" value="Chorismate_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006221">
        <property type="entry name" value="TrpG/PapA_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11236">
        <property type="entry name" value="AMINOBENZOATE/ANTHRANILATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11236:SF18">
        <property type="entry name" value="AMINODEOXYCHORISMATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04715">
        <property type="entry name" value="Anth_synt_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00425">
        <property type="entry name" value="Chorismate_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00097">
        <property type="entry name" value="ANTSNTHASEII"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56322">
        <property type="entry name" value="ADC synthase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="7" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glutamine amidotransferase" evidence="11">
        <location>
            <begin position="44"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="Glutamine amidotransferase" evidence="11">
        <location>
            <begin position="152"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="Anthranilate synthase component I N-terminal" evidence="13">
        <location>
            <begin position="274"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="domain" description="Chorismate-utilising enzyme C-terminal" evidence="12">
        <location>
            <begin position="778"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="676"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="726"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="853"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0005339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="853" mass="95326" checksum="FCA4C2252483ACF8" modified="2023-09-13" version="1" fragment="single">LSVGAGGALTILSDAHEEWREVLLKSRSVVPRYQTDFGICTQILQTDHIPVFGVCLGHQGIGWIHGAKVTYGPEPVHGQIARIKHDNTGIFQDIPQEFEAVRYHSLVVLEQDLPADLVPTAWCHSFPLIIADNPAGQNITAALHNIDRSLGYKSIMGVRHRILPHHGVQFHPESICTQYGKTMMSNFFNISRKFYEEQSRSSTHQHLPEHIRAISVVPILPTLTSSATAVPKFLGKKQTSPYSLIIQALDPSIFPEPESIFSSIFLMGPRSKAASWWLDSARQPHPMSRFSFMGGIEAKSCHNQTNKSRRIWGAAQALIQYSTLHKEIHVRRYKSQSEDSDIKRIKLDGKKANGSQENTFWDWVSHTMSEFDKGSVETVAIGPQGEQLGFEEVPFDFFAGMIGYFGYEMKRESLDGYHTPAEQQCQCTGHAEGGHPCTCDCLRQPDASFLLATQAVAFDHVEKRVYVLGVVNNLKERQHYGVGAPIGFQSRENCQDWIQDVTRSIIHLSTNVSTVGSLRRKSAVTATIPEGPKGGEPYLVKQSRRRRSSVGMLSPCKVDVTENDYIKAIQDSLNYIHEGESYELCLTTQFRVRLPLYQHKREHQEPFEGDDPAYDLYKILRKLNPAPFSAFLSFPTALDNQATKLQDQGGLAANSADEVVGKLIILSSSPERFLKIGRKPSDEPEDPTIGGDASLSSRTVEMKPIKGTVAVAKGCFCKEDEGCKVDEEDDDDNSGHDDSSDDIIDVKSSPTFSTIPRGLGFDRRGRRCSASDRCAEARRREDQCRIDSLSKNIKERAENLMIVDLIRNDLSHVCSSKSVRVPYLMHVESYETVHQLVTTVRGELFDHVDSTQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SUZ7</accession>
    <name>A0A9P6SUZ7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Nuclear control of ATPase protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">NCA2</name>
        <name evidence="7" type="ORF">BGZ80_005350</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002643">
        <property type="protein sequence ID" value="KAG0006099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SUZ7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013946">
        <property type="entry name" value="NCA2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28234">
        <property type="entry name" value="NUCLEAR CONTROL OF ATPASE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28234:SF1">
        <property type="entry name" value="NUCLEAR CONTROL OF ATPASE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08637">
        <property type="entry name" value="NCA2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="520"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="521"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0006099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="653" mass="74086" checksum="7353935130D58C24" modified="2023-09-13" version="1">MEKVCVEIEKVESLLKPALESRQSEEVSRLEHLFIAKCTIAVYLNLLDIILNATLPLANEIQYWQSLLDSRSWRLLYTVQSKSLDENPGNHLESLIGTAAQGSDYQVNTLQLLKFFPTFLSRHLISRPVSFPVAIRYEITHHRKQLQRIREYQAECLGLLAEQGLDLNSEYIEDSISSPSPLSTPNIERLSNQAEQFIQEQVSKTICLMERVLDKASKDTHHVTDPQQQKVPSRNASRSLTVLGNLHGVSIMGNDQSMEHLKKLILVEIPRYVSQTETQAKQFHRPSWLTRIWIPTLIGYFGLKYGIQYISEHRADLDLMLEEAWDTARRFVTDWVWEPSVRIMEIIRHSDNQGSLQMLRNESLKSDIASLERMVLDFGKEQYHLTSDDLASLSSAVHNGDISLIMRAYERELKTPLKGAVVGHLIQTLLIQIQKTKVDVEVAMAALDKLLKANELNFAFLAVGPSLLLLWATTSQVKSVWQRVSGRNMGLVSIQMRNSLRQVERLLNLASADGDGLAHTKQGSSLAKATSPSLAARASDSQDSEEYDDLSNSTTLGTSAVEPLSNSLLQTSEKLIRMRAKKGKVPYKTQGLILCEVHLLRTFAARLTRSEGLRDKVMEDLREIEESSLTIHQRLRTTKRMYRTYGFLGLHQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SVW7</accession>
    <name>A0A9P6SVW7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Dicer-like protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">DCL1_3</name>
        <name evidence="8" type="ORF">BGZ80_004711</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002374">
        <property type="protein sequence ID" value="KAG0007392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SVW7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004525">
        <property type="term" value="F:ribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030422">
        <property type="term" value="P:siRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00048">
        <property type="entry name" value="DSRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00593">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.380">
        <property type="entry name" value="Dicer dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1520.10">
        <property type="entry name" value="Ribonuclease III domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038248">
        <property type="entry name" value="Dicer_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005034">
        <property type="entry name" value="Dicer_dimerisation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000999">
        <property type="entry name" value="RNase_III_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036389">
        <property type="entry name" value="RNase_III_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14950">
        <property type="entry name" value="DICER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14950:SF37">
        <property type="entry name" value="ENDORIBONUCLEASE DICER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03368">
        <property type="entry name" value="Dicer_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00636">
        <property type="entry name" value="Ribonuclease_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00535">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69065">
        <property type="entry name" value="RNase III domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00517">
        <property type="entry name" value="RNASE_3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50142">
        <property type="entry name" value="RNASE_3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="RNase III" evidence="7">
        <location>
            <begin position="272"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="465"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0007392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="484" mass="53204" checksum="8F876E720A6129D9" modified="2023-09-13" version="1">MITLPAIHCSDPIFHAIPPTDSRYIDAISRYCQGLGSRKPIYSPKDTKDGLCICNLTLPGDTSCAVVRIKTNKRHAKSVAARDACAKLIKKGEMDENLAPVMVPSVTPERRNFGNVKLSEARQKELGLSPVPIEMLHVALESNSEDIAFSDLEEALTIRIQNETRREAIMEYFVSSVLAWNVCTGSNPTAYGVKRATDIIRRVIGAAAVHGGVNTVTEITRALGAGVDTALTSINNIRVVHQLNRMVDHDVPIMIRNAQIPRMIDTETAEIMQKVQEALGYQFKDTQLLLEAMTHKNAKTSKSYDRLEFLGDAVLEIAVIECYYRKCPDAPLEDFKNFKCRLLSNNALGSLYASLGLEDAIIVNSSEFKLTLKKEAARANQFKPNRQTGWSSLDLKKTLGDAFEALIGAVFVDGEFSMEPIQEILRQILVPSIDRSGMECPTFATCSVAATRPAATTSSATVLPIGGKRKKMGSAESRKRAKDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWB6</accession>
    <name>A0A9P6SWB6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Arrestin-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003959</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002080">
        <property type="protein sequence ID" value="KAG0008016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWB6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="217"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="250"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="146"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="224"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0008016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="331" mass="36546" checksum="FFEE2A36D3B403B8" modified="2023-09-13" version="1">MRSNKVELVPKQKSLTIHIHTNHTGPHGMPLVYGSTPDRVGFIKGSVRFSSNYDCKGRDIQIIYEAWVETHANDKHSSHHPHKEVFGRKTFTFPLVHTKHNGSVIAAGVYEKEFEIPLIHPAADNARRSFESTSSTVMHFKSSPYLASPPASPKSSPTSSSTSLPLTSASASSESLVLPSSNYSPNSRVRYTIRAVLRRPFPSLNYEASQEIWVVNSDSPRQPSEPSMHSSISCPSSPVSEDPFVVSAPVPEQRGESESTVVTTSPKVDTTSNEMRPKIKSNPMIAKLSNNYFNKQLDDLQTIEQLDGGVSESDSVFFADTSMLQALTYFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWN6</accession>
    <name>A0A9P6SWN6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Beta-lactamase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003369</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001888">
        <property type="protein sequence ID" value="KAG0008497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWN6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052907">
        <property type="entry name" value="Beta-lactamase/esterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43319">
        <property type="entry name" value="BETA-LACTAMASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43319:SF3">
        <property type="entry name" value="BETA-LACTAMASE-RELATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase-related" evidence="1">
        <location>
            <begin position="89"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0008497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="492" mass="54975" checksum="3A2627F7C832BDB4" modified="2023-09-13" version="1">MGVTKGPAPGGGFSPIPRFTAFQWFLHLLPAIIFVAYTYSTKGPFQSSSCIAFGRNCKTFSPLHFEGTIERPEYYKPAVDHLKHLLYTHEDLGGSLAVFVDGKPVIDVYVGSKDLEGTIPYTNDTLQQVYSSGKAVEGIVIARMVQKGLLDYGKKISEYWPEFAQNGKQDVRLVDLMVHESGVFYVDGRDLSWDSLADKEKFSDRLARQPHHFGGKTARAYHAVSRGWYLNEIVRRVDPQGRTIGQIAREELMHDYKDVELHYSHFEKDTDWEERLSPMYDYPVLRIIGRLILPKFIQANKYIGNPDVIPLHPLVWQLIQKWSLSSKSLTPRMAPFAGSFRTKKAHATESTSFSLKTNAHSLAKLMSMMANKGASINPGQEPDLLSAEVYAEATSYHSDLPCTVTFETLPLSRGGWVKSKDFYRDGPLKGVEVQGWGGAGGSLVLWIEELGIGFSYVTNAFGAAEAVLGDFRGKVILEKVVQARKQELGLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWW3</accession>
    <name>A0A9P6SWW3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Ubiquinol--cytochrome-c reductase subunit 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">QCR6_1</name>
        <name evidence="11" type="ORF">BGZ80_002801</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UQCRH/QCR6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001708">
        <property type="protein sequence ID" value="KAG0009042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWW3"/>
    <dbReference type="OrthoDB" id="405848at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006122">
        <property type="term" value="P:mitochondrial electron transport, ubiquinol to cytochrome c"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.20">
        <property type="entry name" value="Ubiquinol-cytochrome C reductase hinge domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003422">
        <property type="entry name" value="Cyt_b-c1_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023184">
        <property type="entry name" value="Ubol_cytC_Rdtase_hinge_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036811">
        <property type="entry name" value="Ubol_cytC_Rdtase_hinge_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15336:SF0">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT 6, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15336">
        <property type="entry name" value="UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX 7.8 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02320">
        <property type="entry name" value="UCR_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81531">
        <property type="entry name" value="Non-heme 11 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Ubiquinol-cytochrome C reductase hinge" evidence="10">
        <location>
            <begin position="40"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="18"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="22"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0009042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="101" mass="11403" checksum="EDD87DD8602CAC3B" modified="2023-09-13" version="1">MLSFITDLFPAVYAEENHEEAAPVEEEVPAAAEEEEEPEDIKPEIEEACGETSACAPLKHHLEECTRRVQEGAHEDCIEELYHFLHCVNDCAVPKYFSKLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXJ2</accession>
    <name>A0A9P6SXJ2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Geranylgeranyl transferase type-1 subunit beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">PGGT1B</name>
        <name evidence="10" type="ORF">BGZ80_001794</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein prenyltransferase subunit beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001418">
        <property type="protein sequence ID" value="KAG0010088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXJ2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005953">
        <property type="term" value="C:CAAX-protein geranylgeranyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004662">
        <property type="term" value="F:CAAX-protein geranylgeranyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045089">
        <property type="entry name" value="PGGT1B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001330">
        <property type="entry name" value="Prenyltrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11774">
        <property type="entry name" value="GERANYLGERANYL TRANSFERASE TYPE BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11774:SF4">
        <property type="entry name" value="GERANYLGERANYL TRANSFERASE TYPE-1 SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00432">
        <property type="entry name" value="Prenyltrans"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="Terpenoid cyclases/Protein prenyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0637">Prenyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Prenyltransferase alpha-alpha toroid" evidence="9">
        <location>
            <begin position="28"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="Prenyltransferase alpha-alpha toroid" evidence="9">
        <location>
            <begin position="104"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0010088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="298" mass="33766" checksum="DC7E2A779FEBCDE3" modified="2023-09-13" version="1">MPSDQASSTTVADATTMPHEAPKEQTKFEREKHIQYLKRSLQMLPQPYTSMDTHRMTFGMFALGGLELLGVLEESVSEANRQAWIEWVYSQQRVPDSQGSPGMAAIRFIQECQTYDHGFSQSPQQESHGGSTYCAVATLGLIGGEALWDQKTMTRNVQDGEDEAAFELRKSRAGFLDKEGTRKWCLQRQTTGFQGRINKKTDTCYSFWIGASLAIMDSFDLVDFDCNRGFLLETQHKVFGGFGKWVDTYPDALHSYMGIASLSFMSEPGILPLDPLLNISKRMQERIYTQTVFWKDSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXW5</accession>
    <name>A0A9P6SXW5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Guanine nucleotide-binding protein subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">GPA1_1</name>
        <name evidence="7" type="ORF">BGZ80_002095</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001506">
        <property type="protein sequence ID" value="KAG0009759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXW5"/>
    <dbReference type="OrthoDB" id="5817230at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005834">
        <property type="term" value="C:heterotrimeric G-protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001664">
        <property type="term" value="F:G protein-coupled receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031683">
        <property type="term" value="F:G-protein beta/gamma-subunit complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007188">
        <property type="term" value="P:adenylate cyclase-modulating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.400.10">
        <property type="entry name" value="GI Alpha 1, domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001019">
        <property type="entry name" value="Gprotein_alpha_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011025">
        <property type="entry name" value="GproteinA_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218">
        <property type="entry name" value="GTP-BINDING PROTEIN ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218:SF360">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT ALPHA HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00503">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00318">
        <property type="entry name" value="GPROTEINA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00275">
        <property type="entry name" value="G_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47895">
        <property type="entry name" value="Transducin (alpha subunit), insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51882">
        <property type="entry name" value="G_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0807">Transducer</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="12"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="49"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="112"/>
            <end position="117"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="242"/>
            <end position="243"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="267"/>
            <end position="273"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="273"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="292"/>
            <end position="296"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0009759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="304" mass="32957" checksum="50694CD5CE6CA6B2" modified="2023-09-13" version="1">MEGTSGSSVPGLSSLTNTLHSLSINNSSNNSNTSQPSSSANGTQSQTNGSSGAAGSAAGGASASSSIIPIISRTEQKKAKAVSDAIDKSLRADKERLQKERGAKLLILGPSETGKTTVLKQLKLLYGRKGLDAERQTYRRVVHLNIMKAIQSLCYGLQRANIPLEHAENIAHLETVMRLEATLKRYSITSIGFTNPAIPRKITDAKAETDMFLDMVPAIRALWADGGIQETFRTGANLNLQDSARYFLDSVDRIADLNYVPTDDDILQARVRTLAVSEHIFNIDGVTYKIFDVGGQKSLRKYWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXX1</accession>
    <name>A0A9P6SXX1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">High-affinity iron permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">FTR1_1</name>
        <name evidence="8" type="ORF">BGZ80_001218</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001275">
        <property type="protein sequence ID" value="KAG0010741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXX1"/>
    <dbReference type="OrthoDB" id="4364at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033573">
        <property type="term" value="C:high-affinity iron permease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015093">
        <property type="term" value="F:ferrous iron transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004923">
        <property type="entry name" value="FTR1/Fip1/EfeU"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31632">
        <property type="entry name" value="IRON TRANSPORTER FTH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31632:SF2">
        <property type="entry name" value="PLASMA MEMBRANE IRON PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03239">
        <property type="entry name" value="FTR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0410">Iron transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="50"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="85"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="139"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="171"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="203"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="278"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0010741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="366" mass="40182" checksum="10889F139931944F" modified="2023-09-13" version="1">MGSDYFSVPIFFIIFRETTEAAVIVSVLLTFLRQVIPEDHAMRRRLARQVWGGTALGLAISLAIGAAFIVVWNKYANNLWATSEGIWVGCFSFVAVIMITVMGLAMLRTAQIQEKWKVKLSKAMGQETERGLGSSSRQYALFALPLVTVLREGLEAIVFIGGVTFTESAKAIPAAVIVGFLCGLLIGYILYRGGNRMNLHRFFTASTCLLLLLAAGLVAKGVAAFETYAWTKATHAQSDDSGSYDPRINVWALACCDPNANNQGFAQLMNALFGWSNVASIGTVVCYIVYWFIVMGALIYMKLKRRRIAVKEYFDKTTEEDMYSEDIKGDDLKEEANDTPSSTSVIDLSRDGVVVGDGIQVAKANH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SY75</accession>
    <name>A0A9P6SY75_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Clp ATPase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_001020</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001226">
        <property type="protein sequence ID" value="KAG0011007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SY75"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000002">
        <property type="entry name" value="ATP-dependent Clp protease ATP-binding subunit ClpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050052">
        <property type="entry name" value="ATP-dep_Clp_protease_ClpX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48102:SF7">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48102">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Clp ATPase C-terminal" evidence="4">
        <location>
            <begin position="537"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="36"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="94"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="236"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="415"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="643"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="36"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="71"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="101"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="129"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="156"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="170"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="277"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="424"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="643"/>
            <end position="652"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0011007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="676" mass="71787" checksum="04A4E5E23429F033" modified="2023-09-13" version="1">MVSFKGRIHRNHTNASCNVAHKALPHRFFTSSTYLRANQPPKSSSTITGASQEASDSVATTTTRVTRKGQSKLATSTSSKADAATNKGVNINAAQAASESHSGEIKTRETVKSRSVSQSGKSDPPSGDNIHSSTVTSSIYPTQPPQPNTFQSRDVIGGGGSGGTGDLFTSRKNAPSAQSTEWLSDIQNPRTIVKHLDEYVIGQEKAKKILAVAVYNHYSRVNENLRQLQIQESLSAASNASQSPPPSNVYYGSSVLMSDGPSTPDPINEPYNPPTPSTTSSPSSSSVASSSSASDSKEANTSNTADMPGKRSGKTLLARTLAKVLNVPFSMSDATPFTQAGYVGEDVEMVIHRLLQNCDYNIKKAECGIVFIDEIDKISKRPDTMSISKDVSGEGVQQALLRMLEGTVVNVTEKNGSSWNGSSGRKGGLPGIGGPNSGGGGPGAKGEIYSVDTSNILFILSGAFIGLEKIVMDRVSKGSIGFEAVVRAPSSELSSSKNAASQVSQLLDQVDPTDLIKFGLIPEFIGRLPVIASVNHLDEAALVRILTEPRNSLVKQYQGLFGLADVKIHFSQSALYTIASQAIEKQTGARGLRRIMESLLLDVMYEAPGSSIKHIVIDKEVVLGKKPAICFARGAESSVTDALDRDDRELGHSHPQLQQQSTGQDEEPPIAEAISV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYG2</accession>
    <name>A0A9P6SYG2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">acetyl-CoA C-acyltransferase</fullName>
            <ecNumber evidence="5">2.3.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_000742</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA</text>
            <dbReference type="Rhea" id="RHEA:21564"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
            <dbReference type="EC" id="2.3.1.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism; fatty acid metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.16" evidence="5"/>
    <dbReference type="EMBL" id="JAAAID010001160">
        <property type="protein sequence ID" value="KAG0011374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYG2"/>
    <dbReference type="OrthoDB" id="5404651at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003988">
        <property type="term" value="F:acetyl-CoA C-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010124">
        <property type="term" value="P:phenylacetate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.47.10:FF:000010">
        <property type="entry name" value="Acetyl-CoA acetyltransferase (Thiolase)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050215">
        <property type="entry name" value="Thiolase-like_sf_Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020610">
        <property type="entry name" value="Thiolase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020613">
        <property type="entry name" value="Thiolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43853">
        <property type="entry name" value="3-KETOACYL-COA THIOLASE, PEROXISOMAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43853:SF5">
        <property type="entry name" value="ACETYL-COA C-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00737">
        <property type="entry name" value="THIOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00099">
        <property type="entry name" value="THIOLASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase N-terminal" evidence="9">
        <location>
            <begin position="34"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase C-terminal" evidence="10">
        <location>
            <begin position="305"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="7">
        <location>
            <position position="119"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="383"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000429-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0011374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="429" mass="45497" checksum="CFA5734E0E52E212" modified="2023-09-13" version="1">MSSSSVNRLGQIKSHFTGGSQREHLINHRHPDDVVIVSAVRTPICRAGKGGFKDMYPEDLLAVILKAAVERAKIDPKVVNDIQTGNVLQELGGIKVGRAAMFCAGFPYTTTYGVLNRQCSSGLQACNYIANAIKAGELDVGIGAGVESMTHDYGSKSMPSRISSAIKAGPGVADVFYPMGITSENVASDFSITREDQDRFSSESHEKALKAQEQGLFNAEIIPVKVQVKSTVKDENGQEKQVVKEVVISKDEGPRPGSTVEKLGKLKPVFKKDGSTTAGNASQVSDGAAAVVLMRRSKAQELGCTILARWCGARVVGCPPRIMGIGPAVAIPAVLKDVGLNVDDVDIYELNEAFASQALYCIRTLGLKPEKVNPKGGAIALGHPLGMTGARQMATLVSHLHHTNQKIGVISMCYGIGGGMAAVIVSERD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYM2</accession>
    <name>A0A9P6SYM2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_000368</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001074">
        <property type="protein sequence ID" value="KAG0011871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYM2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0011871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="260" mass="28700" checksum="8F02CD05076267F1" modified="2023-09-13" version="1">MSSASRQRHYRHHRGAHAHRGAEIDDVSRRQSGPRQSKQAPLGSGDCLPLAPKDSASLKEDLIRILDRVKELESDKTRELVNSESLSQITQEKLALASHALSTEPEDVDLMSKVVFVLFNQDLVKESQGSRTMETSPRTTAAGSTSVEAERKKVDILRALSAVLFENGSNVKDTLQDLFQIISVAGRNAGQREQSELRRMALNCMANMVHKTGALFSDLHDGMYEILLSNLVLTPQYDANPLAGATSATHRKDRGSERKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZ95</accession>
    <name>A0A9P6SZ95_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Testis-expressed protein 30</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">TEX30</name>
        <name evidence="3" type="ORF">BGZ80_011464</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000924">
        <property type="protein sequence ID" value="KAG0012859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZ95"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046879">
        <property type="entry name" value="KANL3/Tex30_Abhydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026555">
        <property type="entry name" value="NSL3/Tex30"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13136">
        <property type="entry name" value="TESTIS DEVELOPMENT PROTEIN PRTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13136:SF11">
        <property type="entry name" value="TESTIS-EXPRESSED PROTEIN 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20408">
        <property type="entry name" value="Abhydrolase_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="KANL3/Tex30 alpha/beta hydrolase-like" evidence="2">
        <location>
            <begin position="174"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0012859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="324" mass="34872" checksum="50617C471A1B222E" modified="2023-09-13" version="1">MSDPTEKEISIPWPGKSAIMVTLTTPPEGMTLSGFGLILGPGAGGDEKTPLLTAVAKEVAKQGHYCARYRARVPNLGFRVSVCTRVMEYLFHPTSGLYPLKGCFHGGHSMGTRVAGTVASQIALKGSEPAAATTVTTITATTPKKKRATREKKATTKDSDSTTTVSSPDFPQDFITGLILYSYPLHTQDNTKSLRDQILYNIPSTTPTLFVSGLNDSMCSTTLFEKVFADMKSSPREVIRVKSADHGLGFGNSLASQARKERLIESIVEWTVAFMDDSIARNTTGKKKKTAKNTAAAADVVTKKTAVLEKNNGDEWTLSLSADV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZB8</accession>
    <name>A0A9P6SZB8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_011176</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000869">
        <property type="protein sequence ID" value="KAG0013281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZB8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="871"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="49"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="188"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="277"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="748"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="835"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="49"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="82"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="199"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="283"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0013281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1060" mass="119516" checksum="BB46DA29A8E321D2" modified="2023-09-13" version="1">MPMTRSNSGNKSRRPQPSDQVQPVYHLFSGPNTEQDTIVNTGGIAHMFTPSVGGSSRSSTFTRSRLPYNDSGLPPQLPPRNNYMNGTFNSNNNASSGQGKGYVSGPEHGSETQKESSTVRFKGLLKSVGLSNQHSPNTFPLTGDFLSGDDQPVSKVFSLKRPERRKKRIKKPRFAAAGVHAALTVATDDEDSSASKSVQHNHHSHRRFWNPRRRSRSIDLGVSHHPIVTYNQEPINQGPVISAALKEAREGNRDPSVLIAELEPLPPSFKDAFAALSHPRASQHQQRQQQQHPQPQPYAPMASHVPPSSTVGPAFASVYYGPIGTLTNYQYIPTPQRSPAAGCSYVIGTKTFLFQSLENSRLQGHYIFRVVGDNIEYKKLPPTLEQSSSQYFKSAWKTYRLLEKTWREEQERRGIDRFWARDLDLGNRFDRSAPLSVTIPRPTQNYSQMSNEIGRRGSEGTILKSAVAWDQLKSTGSVSLTESPVSTPTLPVSNAGYLEQRYNPQISNNPALRSIVDGINRSNSDPIRKGAAAGFYEGGGRNGSTLSQITLRSALYHSRRRSWSSISEQQHSEQQKQQAVEEANWREKERKYREEFQQATYGLELFLKELVKGSEYEIFDAAVNVTISNENRKRTLDQHIFKVVHLDHRDINDLHYISNSIFLVPADSAVFTITNSDRTNVMCLESPSVKLKDEFLNWIKISAMGHEEVEDELIPAPRAKPPKDSSLDFLIANINSYEEKSEGVDLIREIVELRIKQQADRLQAMRENFKMTQKEIESCIHRLDEMNERAKETMTNIARDIDSQEIQLTLRPSPATGMTLAATVEKKVIEVQERIMVCQRIMDEASNNLLRLRNEIELEQRSIRLFRQYKIIIAVVATSIVFLAWFLYQARANPLGPQPPSPLFPESTNPIEVNHRYHHEGISVSTPSISTPTIFAHESVNIVEYEPELDLNHMDFGTMDEIDIEDKDKKLSGEIYEATVTDDILSDEELNSSVETPERSLDEVFGLQTRGNVEQPLENKSLLPLELERETEECVVNSDLLQMPSELGPATAQKYCIIHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZM6</accession>
    <name>A0A9P6SZM6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_010580</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000751">
        <property type="protein sequence ID" value="KAG0014210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZM6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0014210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="97" mass="10699" checksum="22D1F748A60CCCA0" modified="2023-09-13" version="1">MITRSRIDHSVVGLFCSHVWIKSDSDFTRLLDEESFVDLNNLSQVIGSVVGAKEAVSKDLSFIKNDKQAALMPITRAPAMGIKSSIYGHRFGSNKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZX6</accession>
    <name>A0A9P6SZX6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_010192</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000685">
        <property type="protein sequence ID" value="KAG0014842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZX6"/>
    <dbReference type="OrthoDB" id="2429992at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="325"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="18"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="325"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="349"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="372"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="400"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="436"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="483"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="519"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="545"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="579"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="609"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="620"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="650"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="671"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="690"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="713"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="732"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="761"/>
            <end position="772"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0014842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1044" mass="116923" checksum="33B5F0229003CA7E" modified="2023-09-13" version="1">MTTTASTRTAWPSPSIPSPGSSSLQTSGTSSIDTPPSSVHAPPPPLPTLNENDDLDQKMMEFRRYLTSRNSSAGPDLIFNVSEYATFLPRPLGIKERPSEKSPSTGSNNWTVPPSPPRTVSGYAAGFGPPIGPNFRSSRITYPQCAPPSPPELLRESTEMIAKLPVMMSPTIPEWTVPARPVTGGKQPGNIPAVPPDLGASSDESSSDSDRESDHLSSAADSEGAMMNETDTNPRYKSIGRKTAQRRNSKTGMIAGKRLTGYILDKPNSLAGPSAEYCCMLSSEETKELPHRSGKAFLSKSPTVVRINIPSFLLPELETRLKSLSSTLTSKSVSARSPSPPGSPKRKSKSEYKKYHSENETSRKSTKRSRAHSHDLDSDSNSDSERSDAYSRNRKRGDKHSKYEADKPRDMGPSLSPNLDRKKQNNGRMISNGDDNDSKQRDKVDSSSKSAGPIDKSTNSRRRRSSSGSLSPENTNPKSHRKDLRDESRDGSARKRRPSKEDSSRRAGGSSHKDDRGRSTKHRSYGHSRSRSRSPSNSRPRRRSRDRDDDHDIKTSRGRRDRDYDDDRSSSKTKRKRDTSREQYDKPAKGRRDKSRSRSVERDDNRERRRDKKRQRSRSQSRERSDARREKDKHRRESSSTKAMADISEDTQTQKSPISQRKNIEGRRESSNVAQPPTETGKTEAAASPSRISSDAQPQKDSATTSAPTVKKFTMEDYQRRRLESDVGTPKATTDSPALSSSSAVLSSTANDQGGTRKMTALTTEPTSSGQSKYDREYRRYHTMAISLKRKADEISHVQRNPRLGAIVYFLSGNAFMRAFHFNDRHLEHIYSNRPELVLRESMKCWSSMKQFTTALSAQCCDKFPGLDGISYLLEALIYYKCHTYTNQRLRVEMQGSDQFKKRSSKDGSSSADPVMITPGLATKLMQYAEDWANLSAKLEECQVALTPDIAREQFPETFKKWCIHPEDIGNSEGRTFSMTVEQKQKIVVGVVDGVVVHDEKVRTFPKIMWPLGTYMHLSNLMDFAEEALHEYQVRNSLEYNVTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0F3</accession>
    <name>A0A9P6T0F3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">SPT3 Dosage dependent suppressor of Ty-induced promoter mutations-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">SPT23_8</name>
        <name evidence="5" type="ORF">BGZ80_009876</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000631">
        <property type="protein sequence ID" value="KAG0015407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0F3"/>
    <dbReference type="OrthoDB" id="341259at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00102">
        <property type="entry name" value="IPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002909">
        <property type="entry name" value="IPT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057962">
        <property type="entry name" value="SPT23_MGA2_DBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23335">
        <property type="entry name" value="CALMODULIN-BINDING TRANSCRIPTION ACTIVATOR CAMTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23335:SF1">
        <property type="entry name" value="CALMODULIN-BINDING TRANSCRIPTION ACTIVATOR, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25603">
        <property type="entry name" value="SPT23_MGA2_DBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01833">
        <property type="entry name" value="TIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00429">
        <property type="entry name" value="IPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IPT/TIG" evidence="4">
        <location>
            <begin position="379"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="2">
        <location>
            <begin position="553"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="272"/>
            <end position="345"/>
        </location>
    </feature>
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            <begin position="1009"/>
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        </location>
    </feature>
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    </feature>
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            <end position="335"/>
        </location>
    </feature>
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        <location>
            <begin position="864"/>
            <end position="874"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0015407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1036" mass="112602" checksum="2767E97511349A39" modified="2023-09-13" version="1">MPPHSATNLLQTLGQSDLTSFDTTFLHHQEESTIRMGDMRKAQLATPEWNDALLYSLSDSLGRQVFSKPTLTNRLNVKTHVFKKELQEYVPTQIEDRLRIETIIYVELSIVDQNGALVNAYDYARLPKDLFFSQPDKVMSPEEMGTKRIIDIAATLQCPSNNWQEEKEACLRCARRMSAKLDQTESRIMHMLPELHRTETGDALISFRSGVANIQFKINCYCGHKKEKEGFVIRFDSRSDATIASHVTLPLMLYHQNKNRVASRAIAAAAKAQAKSDQQPEQPSNARNVVKSVTSKTKRESRSKPGHSPIGNQQHQIPSPPNSLLDSPVEWTSSPEMDDIMDSSDIPFTVPSPPPPDPLISLFPESISQEQQQQQQPTVALISHMTPNSGPVRGGTLVTIHGTGFTVGEVMYVCFGENIVPIIPQRDHMLECITPASNKAETVPVFAMNAIESNIAQTTFTYVDDNEKELIKLALQRMMNISARMEGPVDNVLNRANEFALWSDLLQGDDSSSTSTLSGGSYSNLEKMVIESFQILDTPSAKNVEGLSIVNNTGHSMLHLAVALQYESLVKDLMLRSVDMAIQDKNGLTALDWAHRLNDQNMVSLLSGATVDSLVAPAFDARDKLAFAAECDEVAHGLTLSVSPGSRPTATDQPNMDYGHGGITAHDVIQLGRTVTKEPTLDLTDQVDPHLGVEWEGFGQGPGKDVLMGDGVVHGLFETQHEDSFFVQQARKDPPRLAGEVVDQDGRFAIQQHQHQPQQDQPQYQKVLSAIPTSSVERLMGFSPPQDGYSPPPLHRVPTDDVVKVGRAGAIDPATATIPWCGLDSVRLPVGGLDHIAPADQDVVATEGCTGGTAAGQSHGVPGSGSIQSITGSSSTQSIMNTARIDFPRLDIQESAAAGVVVVDDVVDVHGQDQDPGQLYLTEQHFEQVISENPVLQAQEGEVVVVAGQVVVDADNGEGGSHNSTAVQAVVQNSRIDVESEPLLFLGGLPVPVSPRSVRTAPMVVPNSAIAAEMKESEDDATKQESSPSAGSEDEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0T8</accession>
    <name>A0A9P6T0T8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008944</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000503">
        <property type="protein sequence ID" value="KAG0016779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0T8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040291896" evidence="1">
        <location>
            <begin position="20"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0016779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="238" mass="24985" checksum="A8082EEE4B358DF9" modified="2023-09-13" version="1">MKLAVAAVFAACTPSLVFALVGVTWSVSNVPSFGLTNVTFRFDIANAPHKAGYYFAQQFRFVGRSDVGYTGLQPRPDSNGQPVVHAVFSSFIAGTTTSDSNCAGNDGSGVSCAVDFSAPYTDGFALEIVKTPDTVATWTGTAVDATTGSRVHIGTWTLPAGTQGITGNQVGFVEYYSWDDGQQHSCDTLPYTEVTFGDPISPGYTGIVGDAYGYGDCVGQVGFQSMRTAKGVQVKVGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T110</accession>
    <name>A0A9P6T110_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008754</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000486">
        <property type="protein sequence ID" value="KAG0016943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T110"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="94"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0016943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="284" mass="31752" checksum="AF384B5025DE5D8A" modified="2023-09-13" version="1">MVYREPETGAQSSQNVGRTQPRQSNPSHILSPRLSASYASQEKLKQEFDPLTQNLVSSASQTEQDESTDSIFTQRGDETLTNDDEPGVLSQPDSSQHSISQTGSSQTVNPNQNPGRPASHGQPKTPTKRPVQNPERVLPYIKQRVIERYPRNLPPAGGETIAAAMQQHLLYLLPCLEEAISDWNQAETEEAQAYWWDVVQSIQGRVDHACDVMSRFLPPPEVRQDPHLGAYVSLLEQYWRRPPQEKYVYVKPPEIIPPAPAPAPASLSNWGNATRDENIVVVDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T144</accession>
    <name>A0A9P6T144_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cyanocobalamin reductase (cyanide-eliminating)</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_008563</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000468">
        <property type="protein sequence ID" value="KAG0017163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T144"/>
    <dbReference type="OrthoDB" id="409189at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0017163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="315" mass="35609" checksum="E166E520BF7F7C29" modified="2023-09-13" version="1">MTATAEQKHIFLTSLRESCRRLGLDVVHPFAAQSFNATEIGQQNPMPTFNQTSTLSFIIGNTKTFWETFLAQHCPSQIETEGERNDPMDYYCERLIPRVTLQALKDAGLYSDKEGQEFTTAFSVAFSHWKVTVPPAGTPPPGSKPTGFVPPPTKTLPIQQVAHAAGLAYLYRVAYLSVHPVYGPWFAMRSIVMVDLPYDVSDNEVLLIKDDSDQTGTFSTDSKPFELNPAFRDISPEEAEAMNASLEATKTVLLAKGWDARDWVEWVAFRQSLTTGRPDWQKWRYSENQMRYHYQKEPELLAESALKFQQGQQGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1N6</accession>
    <name>A0A9P6T1N6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006889</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000343">
        <property type="protein sequence ID" value="KAG0018670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1N6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="241"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0018670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="389" mass="43418" checksum="E91502CEC5F759D9" modified="2023-09-13" version="1">MPSSNSTASATPSLLQPISNEDACSTYFAELIDEMPFAVSQFGLVLTTALEGKQARADSGPTQLHFRSKVIPVSGSADEEPVDFTNFDVTFNPSLFTTFSARCESLLMRAAATATIVDTDINLYELSADELANRATSENFVEALKKLGDPWIQGHYQNFLAFIPNMIEHWSAERARQGLEAKKVGCFCINDIWRLPLASLASKPLTIWTRAVKFVISEEDLLKTEPEIRARCQQLEEEQGLVLGPMTENDVKLMLECNKVSYNEEYGRWIVKRSRCFRNKQGDMVAWAGTHGDFSIAALHVLPEYRKAGLGRLILNSLALFHMRLAREVLASNGNKGEDDISTSSLFAHADCVEGNLPTMAFMERCGWRRVGIYNWFEMSCNGNSVEDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T279</accession>
    <name>A0A9P6T279_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_007028</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000353">
        <property type="protein sequence ID" value="KAG0018554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T279"/>
    <dbReference type="OrthoDB" id="8922241at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000515">
        <property type="entry name" value="early growth response protein 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF120">
        <property type="entry name" value="KRUPPEL-LIKE FACTOR 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="126"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="156"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="184"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="13"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="93"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="16"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="93"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="108"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0018554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="260" mass="28861" checksum="8001069A06EB2DF8" modified="2023-09-13" version="1">MSYTGLFHSFGTRQVSAPSSPAASPPTGTTDSEIWFPDSQHRRSASADNTQFDELSRRYSEGDIVSELVPEMDICLSLFQATQDLSLSNPLQNSSDGLTCSNPGSPESGATPCAGSSSGSSAMGVYKCEYEGCTKTFSRPYNLSSHIKTHTNQRPFRCGHCDRQFARLHDKNRHERLHRGVRPFACDRCQHHFARTDALNRHLKVEGGRNLCNMYLIERNSPKAMPIVEMPPKKINPLILAHFPNFGKESPEGDDPQTQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2F2</accession>
    <name>A0A9P6T2F2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">VASt domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_006506</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the YSP2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000321">
        <property type="protein sequence ID" value="KAG0018958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140268">
        <property type="term" value="C:endoplasmic reticulum-plasma membrane contact site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032934">
        <property type="term" value="F:sterol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120015">
        <property type="term" value="F:sterol transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032366">
        <property type="term" value="P:intracellular sterol transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051482">
        <property type="entry name" value="Cholesterol_transport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004182">
        <property type="entry name" value="GRAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031968">
        <property type="entry name" value="VASt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23319">
        <property type="entry name" value="GRAM DOMAIN CONTAINING 1B, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23319:SF4">
        <property type="entry name" value="GRAM DOMAIN CONTAINING 1B, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02893">
        <property type="entry name" value="GRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16016">
        <property type="entry name" value="VASt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00568">
        <property type="entry name" value="GRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51778">
        <property type="entry name" value="VAST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="VASt" evidence="7">
        <location>
            <begin position="763"/>
            <end position="945"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="145"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="236"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="346"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="459"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="498"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="960"/>
            <end position="1001"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1100"/>
            <end position="1250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1382"/>
            <end position="1415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="41"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="101"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="145"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="388"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="498"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="527"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="547"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="960"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="987"/>
            <end position="1001"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1103"/>
            <end position="1112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1132"/>
            <end position="1153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1172"/>
            <end position="1189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1204"/>
            <end position="1214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1231"/>
            <end position="1240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1388"/>
            <end position="1397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0018958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1481" mass="162940" checksum="DA0CD5AB085C0AEA" modified="2023-09-13" version="1">MNTSGSMNSNNTKSQRVLGFLRKRSSPTSAGLTEGGDDPKSIAISSNSSSERPASPPINSSPNSSNSDSPGTTTSTTTTSQHPIKNMIRRKSVELGRLLDGSAGTSSNSRRGSNNSRSSFDQEALQEIQEKKPPIAMHERGVSNMELSRSTSSLQTGATVSSPPPPASQGRRGNFSLGLPWRPQSEYSTNDSASGLRLGLTKPQRKFVRVFPELADLVVVPSAYCAPCMSTTPPLTPPASTIPSNSVSPSNTSNTFPSSEFSTAPISSSSSITSMSILSCPGHFDDFACALEREILWQGTLFVTAMHICFYGKQFGKIVKVMIDYRDLVSIEKEKKMGVFPSSIRIRTRQQQQQQQQQPAAAELPVSTEELEDQDPPSGTSSSEEEPATPTATATTPTTKDYVLTSLISRDQAYSIMERNWTLHRQVLQNPSDNTGLETPQTEMSDLEGQAPDMFTLDLGGNGGSGARSRSRSGGIISSLRERRRLNSRTYSVVTDEALSSTENVNRPTVKAKKSSNRLRSSTSTNQQTDSWNVGSDDNFPQKKDVGSSSSSSESRRGSVASSSSTEKQENGLIGFIQKRRSGQFKLIKKVPDGNTSANQLDFQSDASLEQQEIIAQNIEVIYPSPPTSSPISDAAIEPSLPSNSARDNSNGFDLLRSCTPPILISPSLTTTKVSHSSSTVQSLAWDGSQEMSLHTRKTSIEALGEKTPNASNDAADATDATVAAGGAGFTGMSNSIANQAPIVVSASPVPPSGPVACGCQRHYKHAVTSLVIPLPLELCFDICFSGKGVGDGDKLTWETHKIKDGSTDIKITPWQHESDSNASGWENQQRDLEYSVTFKMPMLAKSSTACYETQQVTKYDDFLILVHSESRTPNVPYGEHFSTVNQICMTWEALGKTRVKCFTEVKFKKSVMWSSKVESGSLEGSGGYYKEFAKRLQEMAEAQGDQLIAQFAASSSEVKQPASTSAAVQDVTNDAPSSGTESEPHQASASSRAQSLLTQQTHCSSSTTLMSLDAAHPSIDLTTSAATVTKEQMISAERKSTLTTLLSSLTTPGFPGFSSVGGTSSYAVSTPATLLTPTTPTAPVLWGDYVRRGLTFITRSGQQQQQQQQQQHDLASPTPSPQRGVRFVGKSSDSLSSISSQSILSEGSNSSGRYSDPQPEGNRVKFALPTSRKSYITSRLGGSSTVRSIASAPSLRDQRHQHQQQQQQQQQQYYEKHQHHQQQHYEKHQHQQHNHHHHSLPAQGVQQQQERRDGGSYVFLSKAFFIFVVLGMVVTAVNIWHLHSAISSIVEVVHQRQDMFMVSPHKRPSYHHNQHQQPRQYQNYEQYDEYDHYDQFEPYESYASYEPFLPGPRYDHSYHRYNRQIYQSMPYQQWRSQEEYDALNHEPSLSSPSSDSTVHREYQHHPHQHRQQPESISLLEHKIHMLQKYEAMLNEEQRWREGQKAHEEQQSQKDIAAEIAELVAKLENARMDDEQVSSAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2M5</accession>
    <name>A0A9P6T2M5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">H(+)-transporting V1 sector ATPase subunit D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">VMA8</name>
        <name evidence="5" type="ORF">BGZ80_004750</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the V-ATPase D subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000239">
        <property type="protein sequence ID" value="KAG0020114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2M5"/>
    <dbReference type="OrthoDB" id="7676488at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.3240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002699">
        <property type="entry name" value="V_ATPase_D"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00309">
        <property type="entry name" value="V_ATPase_subD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11671">
        <property type="entry name" value="V-TYPE ATP SYNTHASE SUBUNIT D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01813">
        <property type="entry name" value="ATP-synt_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="234"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0020114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="262" mass="29166" checksum="E8BA46847E250DEA" modified="2023-09-13" version="1">MSGANNRLAVFPTRMTLSVMKQKLKGAQTGHSLLKRKSEALTKRFRDIVKKIDDAKRLMGKVMQVASFSLAEVTYITGDIGYQVQESVKNAQFRVRAKQENVSGVMLPVFESYQEGTNANELTGLGRGGQQVQKCKDTYIKAVETLVELASLQTAFVILDEVIKLTNRRVNAIEHIIIPRYENTIKHIISELDEQDREEFFRLKKVQGKKKEAAARETLERETKQAAEGKLLAESNAAGASVHSSPVDPGDILGGEDEDVIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2T5</accession>
    <name>A0A9P6T2T5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Carboxylesterase type B domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_003562</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000195">
        <property type="protein sequence ID" value="KAG0020804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2T5"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040439314" description="Carboxylesterase type B domain-containing protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="2">
        <location>
            <begin position="65"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0020804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="231" mass="24740" checksum="3DAC78E2A38CFEC5" modified="2023-09-13" version="1">MAVLKSILLALAAILVTFQLSDAGPHLPMATGNLESIPCGANLPVICQNTAPRRRLLLEDTSRQITVQTSVGNILGWRNQNSFRFLCISYGEAPVGELGFGTPVAKAPFNGTWSAINYKAICPQLPGSTNFTTISQTFVENDRAKGQEDCLHLNVYTPSIKGTGETGLPVMVHIHEGSYISGSGGYVTLDPGNMVSRGGVVSVSINYRLGLLGFMENGPAWPRSSARSCRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3L0</accession>
    <name>A0A9P6T3L0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Sm protein B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BGZ80_011491</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the snRNP SmB/SmN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000093">
        <property type="protein sequence ID" value="KAG0022679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3L0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005687">
        <property type="term" value="C:U4 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005682">
        <property type="term" value="C:U5 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070990">
        <property type="term" value="F:snRNP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01717">
        <property type="entry name" value="Sm_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000047">
        <property type="entry name" value="Small nuclear ribonucleoprotein SmB, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050914">
        <property type="entry name" value="snRNP_SmB/NAA38-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10701:SF0">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10701">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN B AND N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Sm" evidence="12">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="77"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="192"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="200"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00041355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0022679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="234" mass="23627" checksum="FA5E45454D6A0272" modified="2023-09-13" version="1">MMNLINFRLRITLSDSRVLTGQMLAFDKHMNLVLADCEEFRKVKSKAGSKAPSGQPEREEKRTLGLVILRGETIVSMSVDGPPPPSAEDQKSRISQLSAGSGVAAPAGRGMPVVPGAAPGLTGPVRGVGGPAPGMMLPRGPAAVAPPMSYGRGGPPPAGMPPGMPPAGFRPAPGMIPAPGMPPGMAPPPGFRPMGAPGGMAPPPGFLPRPGMPPGAIPPGFPPGFTPGPPPPGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3M6</accession>
    <name>A0A9P6T3M6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Actin polymerization protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_000175</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000103">
        <property type="protein sequence ID" value="KAG0022473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3M6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030833">
        <property type="term" value="P:regulation of actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20824">
        <property type="entry name" value="C1_SpBZZ1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11912">
        <property type="entry name" value="SH3_Bzz1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035459">
        <property type="entry name" value="Bzz1_SH3_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046349">
        <property type="entry name" value="C1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020454">
        <property type="entry name" value="DAG/PE-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031160">
        <property type="entry name" value="F_BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057870">
        <property type="entry name" value="HR1_TOCA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002219">
        <property type="entry name" value="PKC_DAG/PE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15735">
        <property type="entry name" value="FCH AND DOUBLE SH3 DOMAINS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15735:SF21">
        <property type="entry name" value="PROTEIN NERVOUS WRECK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00130">
        <property type="entry name" value="C1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25610">
        <property type="entry name" value="HR1_TOCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14604">
        <property type="entry name" value="SH3_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00008">
        <property type="entry name" value="DAGPEDOMAIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00109">
        <property type="entry name" value="C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57889">
        <property type="entry name" value="Cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51741">
        <property type="entry name" value="F_BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00479">
        <property type="entry name" value="ZF_DAG_PE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50081">
        <property type="entry name" value="ZF_DAG_PE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="F-BAR" evidence="10">
        <location>
            <begin position="1"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="Phorbol-ester/DAG-type" evidence="9">
        <location>
            <begin position="338"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="8">
        <location>
            <begin position="446"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="8">
        <location>
            <begin position="515"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="77"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0022473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="573" mass="63635" checksum="A61184A943A7C84F" modified="2023-09-13" version="1">MSPIEPDFDSSIVDGTTTSRAWSTILSDTEAMSKDRHQFSEALISKVYDPLKVLATKKDDARKKHIQFAQKLISERDKSAQERDKAKSKYDASCEEVESSKQKQERAYDEKNQEKLKRSYYQDILDMNNNKNSYVLALQVLNTHRKKYYEEDLPELSNHMQDLDESRIEGLKEIWESYIGLETKLTADAQSHLESMVNGVHAIDASVDSAVFVRTNKVPWTTPADHPFESSPTFNDTEELVVDDNARVFLSNKLMKLRRKQAQVTVDINNRLKDMEGLLNLREAYTSNSSLGDAEEVSENIIETGRSITLLQTMAALYDSEINTIVQAVGETGVQNQPHDFKAASFTIPTSCDYCQSTIWGIAKQGFTCRDCGYNCHSKCEMKVPPNCSNVKGGAKAQRNSMSLSPTTVNTMSSLPPEFAPSATPISELSHQASTTVKESESNISLDQVQAHVIYDYKATSPGELSVKAGDVVTVVEGDDGSGWATCRLNGSAPGLIPASYIEIEQSYEASSEAGPVQKVKVLYDYDAQSDLELTIREGDVIVLTSTDCSEGWWEGTLRGVTAQFPASYVEML</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T493</accession>
    <name>A0A9P6T493_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_008355</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000045">
        <property type="protein sequence ID" value="KAG0023730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T493"/>
    <dbReference type="OrthoDB" id="2407485at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="499"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="214"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="277"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="423"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="526"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="31"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="72"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="435"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="448"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="568"/>
            <end position="579"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0023730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="579" mass="63626" checksum="28AEDBA0D8D6EEB6" modified="2023-09-13" version="1">MTEPSTEPGTAPIAIPSRHSQRHQPAKIHTSNSSSYSNLYLSRSPPSGSFLNSPPPMTAPVNSSSSFYNNIGRSRSSSRSGGVVFTTRPRADSEAARTAMEAMVQARLDRITKRLNNFNSRSHELHVQTQELDKVFHEKTKRLYVVEDHLLRLQGKPGLSEEYLQNGPRPRRLTNDLEELRMGVKTLRRKFQAAGSAATTVEWWKQLKDVSDKRQPIDIPSSDNGIESSFQDRSPSNATSARDGLALQKIFINPNSSSDLISPNSSSSSLLDTTHVLASSPKDPQGLRSPPLTPKGPLLGSSLLSKGLEDRHSVKPRPLSIIPDLEEPHSLVSSLSPTSDDGVQEVKLPSLDASGAVAIGSSSEQQDFTHDIDREPRSRILGDFTPPSPAPSTSEVIKLDGDALAAALDEPSMRNDYEMTEKVQPLSDVNDNNSEVDKPTHHKSEAFTETTESHSQQETSKDDQSSPDNWIQKLWRFLVRAEYFLLGTAVLGAMMPDNLFALCVGFLSAIMYGILIIYHRLTADSGKEAPQPPTIENLASRKKRLSSTRTTGARATGHSPSHSSASMKSRRRTSWQKSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MCQ7</accession>
    <name>A0A9P6MCQ7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_008509</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004628">
        <property type="protein sequence ID" value="KAF9992548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MCQ7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9992548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="260" mass="28774" checksum="14210B62F73A469F" modified="2023-09-13" version="1" fragment="single">SALESIGLASKRACLDIAGLIPSARKLIFGNACAIRTDKHYAAPQKEFIACIELGAFEDGINSAVLIVNWLCLIQAERNPRWSIVMSKKSAIIALFVEPMIVAKDPVFVAFMNPVKKVTVHDSKAIDFNVRTVLEHFRSLPIIKYVTISPHVDKTLCPISAYQTYVARLPQPLVPVPHQKGSCHSIVPLIRYFRDASKATGAVRIRVFHNEISRLMFVEGTEIPSKSDGLRPMGSSLAAMTGVPIANTMVQWYWSSPKIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MD77</accession>
    <name>A0A9P6MD77_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="1">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">FKBP3_2</name>
        <name evidence="4" type="ORF">BGZ80_008331</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6 1">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="1"/>
    <dbReference type="EMBL" id="JAAAID010004480">
        <property type="protein sequence ID" value="KAF9992968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MD77"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043368">
        <property type="entry name" value="FKBP3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46493">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46493:SF1">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0697">Rotamase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase FKBP-type" evidence="3">
        <location>
            <begin position="22"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9992968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="116" mass="12876" checksum="342349A7AB26C72C" modified="2023-09-13" version="1" fragment="single">RHDKTDNVADLYSPCVTILFLSLSVAVFYTGYFEDGTIFDTNDNTKKKSNPLRFKVGVGRVIAGWDEAMLTMSRGEKAKITIEPEHAYGKKGVPDAKVPIPPNARLIFDVELVSLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ME62</accession>
    <name>A0A9P6ME62_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Anaphase-promoting complex subunit 4-like WD40 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_007778</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004039">
        <property type="protein sequence ID" value="KAF9994558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ME62"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024977">
        <property type="entry name" value="Apc4-like_WD40_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879:SF9">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12894">
        <property type="entry name" value="ANAPC4_WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25173">
        <property type="entry name" value="Beta-prop_WDR3_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50993">
        <property type="entry name" value="Peptidase/esterase 'gauge' domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="45"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="Anaphase-promoting complex subunit 4-like WD40" evidence="4">
        <location>
            <begin position="46"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="87"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="129"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="171"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="213"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="255"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="297"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="339"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9994558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="366" mass="40024" checksum="FBC149EE88B560E8" modified="2023-09-13" version="1" fragment="single">NRIASGNTDGIVQLWDVDTSECVRTLRGHIVYSTTQLLDTGEYTFRSDTVEVRSVVYSPKGDRIAFVNDDSTVQLWDVDTGECIHNLYGHGQAVNSVVYSPKGDRIASGSDDKTVRLWDVDTGKCVHTIQGHDRAVSSVVYSPKGDQIASGSDEKTVRLWDADTGKCIRTLQGHSGPVRSVVYSPKGDRIASGSSDSTVRLWDVGTGECVYTLQGHRDGVHCVVYSPKGDLIVSGSDDKTVRLWDIDTCERVHISQHHCRGVISVANSPKGDRIASGSFDKTVQLWDVDTGECVRTLQGHSNYVLSAVYSPKGDWIASGSDDKTVRLWNAYTGKCVRTMWGHNRGVKSVVYSPKGDQIASGSYDKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MFG6</accession>
    <name>A0A9P6MFG6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007323</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003725">
        <property type="protein sequence ID" value="KAF9996176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MFG6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9996176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="88" mass="9016" checksum="5C2E3B6DDC1DD41D" modified="2023-09-13" version="1" fragment="single">VNIIVTPNNTVTATATTTTAAAATTTAASSTSGPSVYYWRGVIRVTAPRTTTTSSGMGMKFDRINNGNGFVTMFIATGIVILGSLLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MFI7</accession>
    <name>A0A9P6MFI7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007171</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003623">
        <property type="protein sequence ID" value="KAF9996777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MFI7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9996777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="59" mass="6374" checksum="BDC7E9B2DD5FB8CA" modified="2023-09-13" version="1">MEEVAVRGTVLPGPPADGDAPTLVGQGPGQELEEDAYEIEDEFLPSMERNAPKDRKSYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MHY2</accession>
    <name>A0A9P6MHY2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006025</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002976">
        <property type="protein sequence ID" value="KAG0002109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MHY2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="36"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="194"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="343"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="478"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="346"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="401"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="424"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0002109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="571" mass="63647" checksum="836CD33840DEC568" modified="2023-09-13" version="1" fragment="single">PVEEIKDYTMEDHEESALENWDSWVSQLESFEKVLSDKGLKKEKSKKTKKVKEPKESSEDTLSPLGSAKVNRSGIFGIGRSDTARSRASTLDLPFDSRPLSMSTTLLDDASTVHRQSFQSSRSGESEAPSQFTITPVKKRWWSTNRRDTSSMYRISTTLSMADLENDKRISTLLQMRSSENLTLNTQLMSMPITLTEPSTPAPELSKEAPAAMQTVSNEEEKETEEKKEAEGKEEAEKKEVGEEEKKEVGEEEKKKAQESEDDEPIAPLPKVKAKKSSKPKLLPISTPLAQLLAMNNAEELWQYVQQAKTYATTRMNKGDKRSAAIALKRAQALEARWQEILLEMESSDENTDELLEDDDEEEEEEEESEQEEEVVVVPPKKEKKKEAAAPVVVTPPAPAAAPITPAKTTTIVNNTLNTRNDIQEEDEDEEESYAAQRRRSVSRSSSTPDKYSKYKVNKPVSGGISSVSTSLTIVAEEETNEDGELAVKDADSKAPLGPDATLEQMLESSNTDHLAFYIQRMKTDTVAKARSGSKFAALEGMKNVKILQQRLDDLLEGKDEKGEEGEEVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MIB5</accession>
    <name>A0A9P6MIB5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005968</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002941">
        <property type="protein sequence ID" value="KAG0002504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MIB5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0002504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="112" mass="11435" checksum="793834630A246848" modified="2023-09-13" version="1" fragment="single">TSQLTGQAITDGAGGCAVAVVGMIAAAAGAIACAVIPPPGEVACLGSGAMSWFAGLFSSCMTTAIYECDQIGQSFTGNYHDVRCYAAEWVVRHPPPNGVPTDVKNFYKKCSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MIT4</accession>
    <name>A0A9P6MIT4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_005934</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002924">
        <property type="protein sequence ID" value="KAG0002671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MIT4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="351"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="381"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="512"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="512"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0002671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="554" mass="59451" checksum="24C7FBC79C69E17C" modified="2023-09-13" version="1">MSIPAYSNACLAPDSTGLNVYLIGVPTSNEGRLEMYSVSLSNINSPTATFVTNYTDSSYWSSSAPKFCLAYTGSPNTINSPIMVYQLGPRSYATNMFPNGTVERAGNFNEIGFVSNKLFSFTGAVNNLDWATGFTNTTFQGTGSSWTGARFNASHITDSSLDWDLSIFPSQTPLLSVGTYVASDNTPAQGYHVVFDQNGAGMVYTALSTATLISDTPTDRVQTLSSPQKVDMSGYSLSKLAVPVTMLGVGYILDRAPDGSTMLYSIAPGQSAKLQFVTVSGNVPSFSSNMAAAAVASKIVIYGASNNGAVSFNSFDPVTSSWTGPGLVKAYNPPSQTSSPFSPSQGSKTNVAAIAGGVVGGLVVIALVAFLFFRSRRNSRTTQANAPPAYQDPGKAPNPASVPLMDQDYTQQQQIQQVQMQQQYNTHQSYVPQSQSIYTSQPITVQQQASPVFFQPQSQLQHLPQESYSYVPPTSIPQLQQQPMIFQPQTSETNPQNNYGQVAYATPQTPVSQLNVPAGQQHTSTNQPHTPTDLYYTSQPANPQYIDPSSHYAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MK55</accession>
    <name>A0A9P6MK55_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_005424</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002676">
        <property type="protein sequence ID" value="KAG0005561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MK55"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0005561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="163" mass="18049" checksum="70862C2890BA155A" modified="2023-09-13" version="1" fragment="single">MAEVNYGWLHAYSIDSDSHKLCNPKRKATETLLALDFKRVMTAADVSAVQHINDVLRCLCEAEDIEPVSHCGTLCVAMRAAVSSIIPKCRFASTSEQNICGHCVLLTMPFNAGLVWPVRVDHGVSDARIMLTRGVVACVVNDLYDWKSDCVRGEPFNSMRFNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MLB3</accession>
    <name>A0A9P6MLB3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GH16 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_005225</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002592">
        <property type="protein sequence ID" value="KAG0006560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MLB3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050546">
        <property type="entry name" value="Glycosyl_Hydrlase_16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963:SF22">
        <property type="entry name" value="GLYCOSIDASE CRH2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10963">
        <property type="entry name" value="GLYCOSYL HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="GH16" evidence="5">
        <location>
            <begin position="51"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="237"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="363"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="470"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="22"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="248"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="374"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0006560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="491" mass="55339" checksum="7414270738E101AD" modified="2023-09-13" version="1" fragment="single">CEPEYSNPTQDSTKKKPSKKTKSTDSKHDIESQFDTPQSCFPLPVCRSFTESFKNNKNKPDKNGLHQALIPKANFSGDPDQAHWTSDFDHVAPYAQIDPSSKRLVLKARRDAVKTQSGGGFGATVSSTRWNRYGTFSAKFRSGATGPGIVTAMMLSNPILGEEITIEVTGRDPKTVITDLFRHQDQGTGSPLSSSPSSWLPFLKPGVPVPSMEGLRTRTRRLKDIILQKKQQKSLSTDTVVIQKAEPDTDEDNQDDSLEESHELKKSTAENDMVYKIEWTPDRIRWSVDKQVLRTLTAKDLLKYNGYGIPSHPMQLQLTIWDAGYSPETKAWAGGKTDYGKNDEKEYATLVEWIEISCYDSKESKRNPWPGAEATKRLEQAEKEKKQEIELREKLEESRKKHIADNSSKLNEDPTKRGHLRHGPSHSLFLKNETGWVAGVIDGMVRHLLRWSFILIVLVGSAAYLTEPVSAQKHKPHQVPVTEMKDPKLMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MLL5</accession>
    <name>A0A9P6MLL5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RGS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002487">
        <property type="protein sequence ID" value="KAG0007176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MLL5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036305">
        <property type="entry name" value="RGS_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48097">
        <property type="entry name" value="Regulator of G-protein signaling, RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="221"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="308"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="356"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="489"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="538"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="827"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="956"/>
            <end position="1026"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="154"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="223"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="373"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="494"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="849"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="863"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="904"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="962"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="985"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1003"/>
            <end position="1012"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0007176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1156" mass="129687" checksum="1CC59FC2DAF693A4" modified="2023-09-13" version="1" fragment="single">MDNLGFQGMPRFPLTPAEEALLPRPHTSASQVATALPSTYIRNGSNSQLSLPSQGQQHRLQYSRKNQQNNPYSTNQGPRIFSFSFSSSSIINRNQQSTPPSSPTTPSHNGPTFNNSETDEREYPQNPQDGCHDYDPHLHSPIPHWPSSPELQPPRRSFSNSPRPSRTSSPQLYNDLHENASYQCQYSSPYPPHRVSLDSHPRLTSPLQIVQGYQESWESAVRVESPVPLSDSESSQSDTKSTPHNGEPRRLGGKDMSSRSQRSPVKRNTANDSAPQHRTSLDSEYVTRFSYDSQREVLTKTTRSGSNLYDISDEERQEPRKTRPTWRPSLSLIRQESSAFNVLALQDQRRYLQNDQRRISDTPAPNEPSKSKSNGHARKKRKGLRKRPRQRSQFESHTEGSKTLPSLHEVLEKKSRYPLSYDDFEAFLRSQCAVEYLNFWADVTAHEQLCRTFNVSERRLKREYQLEERALARDRRRLARPTEYEMACTIQGPDGSSQEQGSLHNRTGTSEQVVKNSIFYRTSRSSLQLPLNDHLSFPQEPHRYGIQESPRSYSPAPYLTSQRQGSEQRIAGTYNRLLAGIGARKSSLDASRQSFDVIPLDNDATLTDIPPTMTQIQEPGSVDGPRFHGRKSSIAMDYLGNGMKPSGSQLSLSLQRHDQNIRGDVAHPVEAVGRYADSPLGNRTSQQSLKIVEPIIHKKPSVVKFDGAVDPPQTLPTTRRSSEGAFSPTPYSVVHDGRPLLAQSYRTISLEDVEESALRIYRKYLIQLRSSSMRKEEEEAAVGPMAATLVGIGIPNTTMSPSTVALDWEVNGEQVIAEWNEKWRGRSTEVRRAKRMSNRRDTLNNGPYSHDKEDVSEKDTPQPAANTSDNNNTNIMGVDLNEKPPLSEDDEDMTVEDSVPGVGKRSRSGAPRRPKADRDSTVTGITSFIARLLRTETTVLELPTLTINTTTVVTDVESGSSEYDDDDDDYDSDDMELDEDEEIQDGNRRLEAPKMTFEKRTESSSVDNTMGSSIIGDPAPSETGTNSSAIQLQHIVPRQPIGERSEIGSQVHGAQLQEKPRNLESAGISSLVSPPISSSGEVAQSTEAGAFYLPLDCRERIHVKIQQEKRIDGVHVFGPAKRFVVDVVLQDHYFPLFLKQIKNQNLGLLHHDHVNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MM85</accession>
    <name>A0A9P6MM85_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004926</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002465">
        <property type="protein sequence ID" value="KAG0007221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MM85"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="452"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="453"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0007221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="473" mass="54008" checksum="230F4B658D191FE5" modified="2023-09-13" version="1" fragment="single">TLKSHKSDRGIPPEIAAFVRSSTLVRPNKEMWDHADLAIFMCPNLTELKYRAISLAGANEIDYETERFLPATPGCDTLRISSQVSAVASRLKLLTIIAYVERYRDFRSIDTLLLLMVFPPASVTDNRQLAIKSHISEDLGWFIVKAFPRLEVLSVTNIVPLWAERPDEISTDITRLGLAQVGSSSEREVTLRKAPFPELIKLSIANSYFAELRQIEAMRARDRNTLQLPEKLQHLEITESRIHLLLEVPLDMVLKHLSINLRSPGFVKEILMHSCCWSLATLSLYEGVERFRDILTEGSSSKATRSVVMDTSTLTSSTTDNATQVENSWESDHLEESFVRSRLPFVSALRSLFLNGAYDSVMPREKAMFINKLLRCMPRLEDFLLKEPLDDIEVAFNRFGDGQAPMLTRIRELSFTVVYPASVELAERQLRERFPSVKVVRIKFRDFQAWNDGSDDDDDDDDDDECSELQQQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMU3</accession>
    <name>A0A9P6MMU3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_003799</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002020">
        <property type="protein sequence ID" value="KAG0008156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMU3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039245">
        <property type="entry name" value="TYSND1/DEG15"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21004:SF0">
        <property type="entry name" value="PEROXISOMAL LEADER PEPTIDE-PROCESSING PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21004">
        <property type="entry name" value="SERINE PROTEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13365">
        <property type="entry name" value="Trypsin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0008156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="508" mass="54541" checksum="86176061DD33372F" modified="2023-09-13" version="1">MVLCPNSGVDILFESDIDDDGNEIWADVDLVAVVEAEGMLSSIRRLTGPDPSMWVFGWGTNKSQIGTDLNSIHRFSLRNVGISGLAILRLKPGAQRPSNVKGQTAMNESFRFPYHLSVPSIGKPLTLHGSGFGLIAPSVLINNISQGIVSNIIHPYRAARRADQQANSLILTDAKFLPGMEGGAVSWGETGELAGISMLPIRRTDGEPVDISLVIPAACIITAISPYITIPQKPLLPHHIAALNSSSLVSARQAVVMVQAGQTWASGVLISKQGHILTNAHVFTSFLDNISNRTWPNLRTGVSLRVRIDSPQQQQWVDDCELVFVSESCWDVALIKIPETCVLNGFLPFLTLRTKGGLSRVKPTVKGTPLFAIGHGIFGPSSGILPLITSGICSKVVNYSDQPVMLLSSAPVHRGNSGGVLVNTDGDFVGLVTGNGKTSTGRTITHLNFAIPVEAISGAVNAYLADNDRKWLDKLNTPPSRIDDIWSLRGAAPVWEPIEKAHQVSSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMV8</accession>
    <name>A0A9P6MMV8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Crinkler effector protein N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_004380</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Host cell</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002236">
        <property type="protein sequence ID" value="KAG0007671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMV8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043657">
        <property type="term" value="C:host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045379">
        <property type="entry name" value="Crinkler_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20147">
        <property type="entry name" value="Crinkler"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Crinkler effector protein N-terminal" evidence="5">
        <location>
            <begin position="35"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="7"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF20147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0007671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="712" mass="81029" checksum="25BF70B3FDDA4535" modified="2023-09-13" version="1">MATTQGAPIASSSSTAPAHASTLDNKDSDMTTQPKLLCLVEMDSTLFSVDYVPDAIIDTLKKAIYNEIATDSSFKAKDLTLWKAEIPTVRGAMYSRDYKRLVDDIKLDPNNKMEADDKLRDYIQMALSKTIQIIVQTPSSELKRRLDQDDLMRPLKQFKPNSTVHKEVRRLVYYADQTESNKPLIERIRLGEFVRVYGARASGKSSRIVDAMETLTAEGFTCIYVDLQNFNVNNLWSSLNQRLKVYGPVNFNDSGGFEETFSVNGNMWERPVVIFFDEFDILHRENWKEARDSILGAIRSLKNDPPKHVIRSIVSIGTYAILQLNQTGQELSPFNASDNFQNTSLSLDQVRELYLEFAKDREMVIEDNVIGDIFKKTNGHAGLVNICGVALEKYRLAQPSGRYVDMNDWGSVQNSLISSMRLYGTFQKLVTDLTEKNEKQKSALTLYRSRFLGNPSETEVSISDVSHHLARYLTALGVLRPGSEEDRFNTASPLMDSLIRQTIIPDAFPDAPKIKPPTRSDHSLDILNVIKSALPLFDKDLIERAHRVSHKTATSPIRVDRIPGRRVPRESVYDSEMTRILMNWLSSQNGYQVIGQYNIGGLFCDIMIRIGELPYPVAIELVVTETSQVIQEHIDKTVNYKNLTKANEGWVIHFTREDNYLKNPLWQNSEMLDKGIYMIHVWHNADFTEVRLSARWKDSCGDVINVDDERII</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MN18</accession>
    <name>A0A9P6MN18_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_004257</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002190">
        <property type="protein sequence ID" value="KAG0007766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MN18"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0007766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="389" mass="44247" checksum="CFD869A6A1441EF1" modified="2023-09-13" version="1" fragment="single">MDISSYFCEPWGTLMKIMHDILRSGRSDKAFPSGDNLSPTRKALYMYICAHLDDRTATLQYEKDLLVAMSGVINLWAADIRDMFGMRLINDIEESAPKSQPDCGVNDTLQSLNEILTIYGIKYLHDEISILDAERVGKVRRGEQVDPLLKIVLDVVRFLADKIIAGTFGESEHAVVSAWKNVLDFISEGLLKFKTGELTSDATKEIRTLQEKELSGTSKNVCGRKMDLHLHLNDLELDNSEFKAVGVNIEENKKQSRKNIRINKAILIYLQRHIRFELKNDDYMVFLDVSGYSGAIVYLKRYNDIHVSGLLCQAPIKLPINEKGLSVFLKGQSFGWLLTYVKHLLHMQQEVEDAQVQAMDSRFMDQEQTTPPTSPRDIDTIVMNTPKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNE5</accession>
    <name>A0A9P6MNE5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_003623</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001972">
        <property type="protein sequence ID" value="KAG0008282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNE5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16189:SF3">
        <property type="entry name" value="AMINO ACID TRANSPORTER TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16189">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 104-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="34"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="70"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="94"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="360"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="238"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0008282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="396" mass="42467" checksum="3581F3618288A179" modified="2023-09-13" version="1">MVSILGAMAFDIPSDSSLIQAINSSPGATTLSKIAGFVFPIAALVTSIPVNTIVLRYNLIRSGACNKSRANFLAVGLPWLFAIPGMTGSALTTSVGWCSLFFVSATTFVIPYVLFISAKRFKRKMKRLEAAEGEREGRQNKESTMTAFFDDGSLDGTISGSLMGLAFGRKADSGLTQSGCDTSLPSKSKEESNGNASSVMDEFECSGTGMLHHEEKDQQDPEIRCHDLEKMPVHCRADGASPPSQSVSPKTAFGAMSSSIHRRARIQSDQTESIMPPFSSGNNYAIPGFGMCQTRPEPLSRTSSELALHHSKPESDTISPIAETVGGSEKDLESCFSQTHGELTLKSAIQAIPRWAPVPAVVIAWSSLTLTLIDIVATIMYSFLVHSSPCSPLRDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MP46</accession>
    <name>A0A9P6MP46_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Core Histone H2A/H2B/H3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_002983</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the NFYC/HAP5 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001765">
        <property type="protein sequence ID" value="KAG0008859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MP46"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016602">
        <property type="term" value="C:CCAAT-binding factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22908">
        <property type="entry name" value="HFD_NFYC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000006">
        <property type="entry name" value="Nuclear transcription factor Y subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050568">
        <property type="entry name" value="Transcr_DNA_Rep_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10252">
        <property type="entry name" value="HISTONE-LIKE TRANSCRIPTION FACTOR CCAAT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10252:SF8">
        <property type="entry name" value="NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0010">Activator</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="9">
        <location>
            <begin position="54"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="144"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="209"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="13"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="144"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="209"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0008859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="248" mass="27924" checksum="6E6FF4FA6C88D046" modified="2023-09-13" version="1">MAHQTPDMYEQQSSSGASSAPAVSSTPAQNALTLQQQQQQQFAQDFWEEQILAAEQSDSDFKNHPLPLARIKKVMKSDPEVKMISAEAPILFSKACEIFICEITRRAWLHAEENKRRTLQRSDVSNAVSRSDQFDFLIDIVPREEPSKPSKRSTTREDSASNAEVFEDQQQQYGQYYSQGNLAGYAHAIEAPSLYQPMSSEQFEQYVQYQQQAAAAQSYQPQHQQHQAPSSRGGSAGYARQEPVSRQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MP66</accession>
    <name>A0A9P6MP66_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_002698</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001676">
        <property type="protein sequence ID" value="KAG0009142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MP66"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027324">
        <property type="entry name" value="MAP2/MAP4/Tau"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001084">
        <property type="entry name" value="MAP_tubulin-bd_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11501">
        <property type="entry name" value="MICROTUBULE-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11501:SF18">
        <property type="entry name" value="MICROTUBULE-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00418">
        <property type="entry name" value="Tubulin-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51491">
        <property type="entry name" value="TAU_MAP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="71"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="113"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0009142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="148" mass="16821" checksum="7A69B711B6FE2686" modified="2023-09-13" version="1" fragment="single">PSRRSSFKIPPSKKVDYSKVRSKVGSLENLHHVPQGGNLRIFSEKLSFRDQAQSKIAKEINIAQFYDYSRENSIQEEGQEGEEGEEHNQSITHSSEVDDEFQPPKNILSVLDEMTESVDELDLEGQQQQQEQQPNDSHDAHVEPTAAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQ43</accession>
    <name>A0A9P6MQ43_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_002558</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001635">
        <property type="protein sequence ID" value="KAG0009277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQ43"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="344"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="386"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="506"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="398"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="432"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="510"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0009277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="579" mass="63936" checksum="6B81723EFBB0CA08" modified="2023-09-13" version="1">MHASTPLSTAQYLIAVTQGWTIYIISAIFSIAQLIQCKLSSETSNGLRLSGRVIYLPANRVSWSQLEDAEEDESDKDDNDTDLDVSDTREELTIVDRQVTEASKYQNSLSAHVAIKKLWAILAAVGDQGWYYSGTMTTVTTEQRLENQVDRMVVKEEEAKEKNQTQGSTNDATPSKDNYSNRIRRALVRTISGNLIPQIKRVTFSDQIVILDKGESLEKGQPKPSREIAGIQTTTASIKSSSSTSTSEFSLNTTKIFIQQQDVTRKRRSSNVFFPPSQMNSKPTAAPSAVIPTMFSSLMAPAAPSTVSITTATAKTTISIDTASSMLMAIPIALESAISANADHHTMEKNPGDSHGNGVTQRKRSISAPSKSSAFLQRYRQELQLRQRQLQQQEGVEAEERLMSTRPQTHEQDKQGDSNTVAIPPDNSGHGTVISISTPTPTSAYTSQSSTLGLGPLSLRTRVHQSLSLIRPHSMQLDMTSMFSSAFSDSKTQEYSTLRRKSFDNEDFKTTSSLASEAPPSSLTTEQQVSGRREEGVTVATTAVTGIEYRNLIFRLAHPHRYKREMEQQQQELSRQVPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQC8</accession>
    <name>A0A9P6MQC8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">hydroxymethylglutaryl-CoA lyase</fullName>
            <ecNumber evidence="3">4.1.3.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">HMGCLL1</name>
        <name evidence="8" type="ORF">BGZ80_002455</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>(3S)-3-hydroxy-3-methylglutaryl-CoA = acetoacetate + acetyl-CoA</text>
            <dbReference type="Rhea" id="RHEA:24404"/>
            <dbReference type="ChEBI" id="CHEBI:13705"/>
            <dbReference type="ChEBI" id="CHEBI:43074"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="4.1.3.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Metabolic intermediate metabolism; (S)-3-hydroxy-3-methylglutaryl-CoA degradation; acetoacetate from (S)-3-hydroxy-3-methylglutaryl-CoA: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HMG-CoA lyase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.4" evidence="3"/>
    <dbReference type="EMBL" id="JAAAID010001606">
        <property type="protein sequence ID" value="KAG0009381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQC8"/>
    <dbReference type="OrthoDB" id="1905920at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004419">
        <property type="term" value="F:hydroxymethylglutaryl-CoA lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046951">
        <property type="term" value="P:ketone body biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006552">
        <property type="term" value="P:L-leucine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07938">
        <property type="entry name" value="DRE_TIM_HMGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000201">
        <property type="entry name" value="Hydroxymethylglutaryl-CoA lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000808">
        <property type="entry name" value="Small GTP-binding protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000138">
        <property type="entry name" value="HMG_CoA_lyase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043594">
        <property type="entry name" value="HMGL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004283">
        <property type="entry name" value="PRK05692.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42738">
        <property type="entry name" value="HYDROXYMETHYLGLUTARYL-COA LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42738:SF7">
        <property type="entry name" value="HYDROXYMETHYLGLUTARYL-COA LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01062">
        <property type="entry name" value="HMG_COA_LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="7">
        <location>
            <begin position="225"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0009381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="535" mass="58111" checksum="F01E402A28381BB4" modified="2023-09-13" version="1">MYSSLLEAKVVILGSQGVGKTSLVVRYVQKTFSLNCTSTIGASFMTKKLVVDNCKVRLQIWDTAGQERFRSMAPMYYRGANAAILVYDITSEESFRDMNSWVEELRKNMTGDLIIHVVGNKLDLAPTKRAIPLARTEEYVAKTLGTEFSVHEVSAKDDDGIEELFLQITRKLVERKHEIERIKRLNAENAITLQQLEDERLQQAQTASNSSTSSAALANSSSRFVKIVEVGPRDGLQNEKSVISAETKIEFINRLSDTGLSVVEATSFVSPKWVPQMGDAKKVITSIKKKENVNYPCLTPNIKGLDSAIESGVKEVAVFLAASDSFSKKNINCTVEESFDRVKPLIAKAKEHGILVRGYVSCVVGCPYEGPISAKKVAEVSKRLYDMGCYEISLGDTIGVGTPGNFEDLLKEVSKVIPMDAIAVHCHDTYGQALANIHCALEMGVRVVDSSVAGLGGCPYAPGASGNVATEDVVYMLQGMQYETGVDLQKTIATGNWISELLGRSNGSKAARALTLKAAAAACPPTSESPVKSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQP3</accession>
    <name>A0A9P6MQP3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_001532</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001351">
        <property type="protein sequence ID" value="KAG0010382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQP3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="800"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="381"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="549"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="845"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="918"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1122"/>
            <end position="1280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="8"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="388"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="406"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="565"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="851"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="920"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="941"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1128"/>
            <end position="1140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1165"/>
            <end position="1178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1180"/>
            <end position="1194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1231"/>
            <end position="1260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1266"/>
            <end position="1280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0010382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1280" mass="141291" checksum="05F5583227630A5E" modified="2023-09-13" version="1">MTHIGQIPASSPKNDFNSQQAQSTPGPIMTHNEYGTTSGLILDPTMAVQTITTPTPAVSSKNTHHSVSNVPMLDAQTMVHANFSAAPTFNQAEGCFFPFEDQSQFPQEIIVPHSPDMFSWPQPSASSTEGADIEFISDLLFREFVNDYDPWVGCSQSQQHNSAIPEMVHEKHSSDSSYGHFLIDQHQEISEPSSVTSMNQQVFDISTFEAENTTASQISTPVAEKLDLASAFKPHSQHLHAQQQYQEPSVDVGIAPDGYFSLPVTTCSPAVLSFSSTSSSGAGPHPQLCDNQVTSNVSHDHGAYNMSTPEFLSSAFESATPSTAGPITPLYVPPTNPQLGCLTEANTMHLLRQLQEVQEKGRGPIQTVLEYVQGQTELHCTPGEQQQSSPPSLDGDGSSTQAGHNQAQLQRQSGQQATDQQQQQRLLVEEEIKREDAEKNEVGQYIASQDNVQECFKPEMNVSNNQDGCVSGLGADNYSPEFLPLPHSFLQSALRNASAIVDNGAAHESVVHAQAHGPSLPHITQVQIRNELDQHRRYLERSLNQSCDQSLTTTATIPPSRHPALSSTAGDSSRDNGNSLTQDQAVQEIYQAQLQLLEQFHSDTTSVVNLSPTAQGFNLNEDYHQCDHSQGDDMHHEFLLLQQPLSQQSLNLLSDYDIQNNGNSIVPDTLTTQQASVIQAQQQKLEELQKKIEQLQQLQEQRPIAPSDIAVPLSAIQALPKGGKTLLGLHPSSSPITLHTAQAGGRDRNLTAEVKQDFSDSILLNNGYENQQGLRSFQNASNDYPRMEFKHAYENQTLSIKCKVPSCTRTFASLGLLKSHMVSHQEDKPYWCDICSYDGVNPRPITDDPHSAGPSRSSSLRSVARSTANSTDQPKTLFYEVKRYKRNHDLLRHKREQHPPIEVKLQREAERIAARAARKARNEVQKKEKITARPKGKRSRASAPAPTMAKATTAGSEVVAAVQNHLPQQEDFGHMNKSQSPSLPADFNLGNGFERGVGMPFAFENSQSHHHHHHQQQQQQYHYEETSFYSNTNMPPGHVRAGNPVYHSQVQVQVQHVQNYYLSFPVTSPTLHPSNFSMSPHLNRVSFSPGSPVFGMFNNTPQMGPTAVYLDDDLPHAIIEPIDTSEEGSSSPDGSATSGSTKFDTRNPDTPDSCPVEDNVRVDSESEDCSTDEEDGDENGYQQLQQQRNHGQSLPTRTTTTPSPPPQQMLSKGNSGGSYMGRRRKRSSLDLTDEDSDDDDADENDDDDDDNDDDDNDDDYCPPNNRRSRQGQRNKIPRHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRF5</accession>
    <name>A0A9P6MRF5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_001004</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001220">
        <property type="protein sequence ID" value="KAG0011037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRF5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051553">
        <property type="entry name" value="Ran_GTPase-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45982:SF3">
        <property type="entry name" value="F-BOX PROTEIN POF9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45982">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00415">
        <property type="entry name" value="RCC1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040287106" description="F-box domain-containing protein" evidence="3">
        <location>
            <begin position="25"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="domain" description="F-box" evidence="4">
        <location>
            <begin position="10"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="1">
        <location>
            <begin position="91"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="1">
        <location>
            <begin position="499"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="314"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="566"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="316"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="335"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="578"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="589"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="672"/>
            <end position="695"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0011037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="695" mass="77571" checksum="08ABD5BD3516F562" modified="2023-09-13" version="1">MRGARAAVTILQLPFEVLVGGILAILPPSDLVCMSRVCKALYGLYQSDYLWQQKFFKEFHYYRPNKTLRQQLGLGGTDGGWRRIYHAMDRVEVYTWGANIDCRLGYGRTSRKIYESVPKRIRRLDGIGIVQLAPTGWGCHALDKHGNIWAWGRIMESNLVRVDAMPRMLKRPRNVIQLSAGRQVVLAKDTNGRIWQWCRENKAVEVTFGSRSDNVSTKDPVEQISAGWDICAALTQSGRIFTWRPPQSTEVRSQLRIHVEHSVSLMDQGYDEYEAAISDGDKFVQIATGSDYIVAVTLLEKVYIFRKLDSNHYHRSANSSNQPKVQQHPFPLAQQHHHHHHHHQQHRSEEYEDRILVETSADGSQQEHVIEIRGRIIGEGLYLPIFSEALTRTITATYEECDEWERRQRHRRHHPNHTSSSAPTTVVEACCSLSSSASRPTTLSASSESFAIHHSSGKVLWGKGDVQSDTLPIVIERLHSNVSQVAFGEHHQGLLTEDGQLHTWGSFSHGALGQGDLRYGCQVPTIVEGPLKNKIVIGIGMAGWQSACLAIDLSEEKEKAHGCFYDSQSRGHATGKGKGRELIDDGYHSLESTSNGSVSGSGSSSEGFDSSDGEEWTLGDNDSKHDNLAGGISADGSTSHATHHHMLHSLFNPRHGTASTHSRPTPVRKRSSSSVERYTDNYGNNRGYHSSNGVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRJ1</accession>
    <name>A0A9P6MRJ1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Swiss Army Knife RNA repair protein HAD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_001499</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001341">
        <property type="protein sequence ID" value="KAG0010422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRJ1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031428">
        <property type="term" value="C:box C/D methylation guide snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990259">
        <property type="term" value="F:histone H2AQ104 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008649">
        <property type="term" value="F:rRNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000494">
        <property type="term" value="P:box C/D sno(s)RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018812">
        <property type="entry name" value="SAK_HAD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10335:SF23">
        <property type="entry name" value="OB FOLD-CONTAINING PROTEIN, NUCLEIC ACID BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10335">
        <property type="entry name" value="RRNA 2-O-METHYLTRANSFERASE FIBRILLARIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10307">
        <property type="entry name" value="HAD_SAK_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Swiss Army Knife RNA repair protein HAD" evidence="2">
        <location>
            <begin position="49"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="587"/>
            <end position="614"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0010422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="638" mass="72280" checksum="81E027B049BDFF31" modified="2023-09-13" version="1">MQDDQEQPPYSLMTHAAVVYSSDRLSNTAYTFRLHTVNVFDFDQTLFQSPLPNPSLWDRSFLGVLTSWNYCGTGWWQNPSTLELGPEVEANCWEGWWNEEVVRKVKESSEDPGCMTLLLTGRYGPTFSQKVIEMVQRKGLDFDIIATKPTTVAQIENDSSNNNHQAPTTELYLKVDTFNTKHDLLYNLLFEYPNIRNMHLWDDRPCQIAKFREVGQKWLDKNMLDHFDVTTIQEPLLYMNPQREIDTVLAMVESNNQQADVEANGGPFLVPGVGPLPRIRPELRDLNMWEPYETYTPKPRNKIEVTKVARYTGVMFSDAVQRVLRGKFGAGNGFKGRNDDVSEEHWIRGPQNLEGMNLGKWVVPDDIHVTLCLGAAQPDFIKTIGGLGATVLVEVEAVGEHEKRIWALRVKEFDVNSCNDSTELHIVAPDGNVYTSLGALRSAYASREPQQENDFPQEESSVREVGAYMAKRLCGSSLEGPYSNVDLDHLGHIVLNRDIVPHITMAYDRLNGTRPVDSGLIQNWESLTTPNGEPFQPRLVFVGTISEKYLLGMKSLKTKHSSSSSCRDVVNLAAVVKTTRSKKNIPRAELGRLIEAIKEEMEMLSVENKTSNLERIEIIAQEVWERAETMKATKLLPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRK6</accession>
    <name>A0A9P6MRK6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">NADH-cytochrome b5 reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">CBR1_1</name>
        <name evidence="13" type="ORF">BGZ80_001808</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001420">
        <property type="protein sequence ID" value="KAG0010082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRK6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06183">
        <property type="entry name" value="cyt_b5_reduct_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.80:FF:000019">
        <property type="entry name" value="NADH-cytochrome b5 reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001834">
        <property type="entry name" value="CBR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370:SF184">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0274">FAD</keyword>
    <keyword evidence="4 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="12">
        <location>
            <begin position="56"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR601834-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0010082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="245" mass="26661" checksum="E3691A274A2F35D1" modified="2023-09-13" version="1">MTLTNASIAAASGILIAGAYMVEPTSIPFVAAGVAATWVHRLVKKKGPRTPPLDPKEYRRFILVDKVVASPNTAMYKFALPHEDDVLNLPIGQHISVMANIGGKEISRSYTPTSSSDDIGHFVLLIKIIRAIVKNPEDKTKVNLIFANVAETDILLKAELDELSAKHPQFKVHYVLNNPPEGWTGGVGFVNAEMIKEHIPAPSGDIKVLLCGPPPMITAMSKITQELGYDKVNAVSKLPDQVFKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRU6</accession>
    <name>A0A9P6MRU6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001262</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001285">
        <property type="protein sequence ID" value="KAG0010686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRU6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="331"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="467"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="657"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="870"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="467"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="485"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="661"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="674"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="882"/>
            <end position="893"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0010686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1062" mass="118787" checksum="802AEF508A82C104" modified="2023-09-13" version="1">MSFANLPISPPRSMPPECLERIVYHASQDHRTLSTLMQVNSTLFRMATPYLYHEPFNFIFGDEFMLDWDTATWTRHLREVRHAKLLLLYLSCSDLVQSMLSTGKGQGLSSRRNSETPAYWDCKDPTRNGNINNNNNNGNTNNGSNNNWRQGHSSSHPTLLEPDTDLRSTPSSPPMGRIPTLLEKLLREQCLRGGGPTSSSSLVSPLRLSMSVRQKTSTSNHAGKKVGVNLSGLSVNYLDYVEHLDLDTFLSTSIQVLFSPSSSARNEHGCGTLKIPSYQHHSSTAKLSQYSMERAFVERALLRSMAQHITTLSVSVATFVRLQRDLMEHVLEPTSPSPPCPSSSSPQGLKNSAGIRTGMPLSQLSRLNISGLHAELKPKVLRAIRWFLRRHVVVYPGMLKAIAFEGPGDIIVNRRRQRNRNVVAVEPVQPGVVHFNNQHADDDTTDEIEEEQDHVAPLPQNNTLTQLQQLQQQQQQQQQNQNQHHIQHQHQHFYQHQHQNQIHNQTQNHNHNQHGNTQGLFVDGAGYVNNVPPNNTTAVPAEALPAVFHSQYYLLRRNPDESSEVDFMGIIQELHGQLEVVDLSQWSWSVITQQALDMIPVAKLSTLRFHPRTRIQWHHGPSFLSDCPALKVLEIHAFDPAMLDLVGNIGFAPSVTVQNHPSSSPSSSSLSSIDPPPPPPRPSYPASLNTLSLTGSVPNVLPAVRDAIRIMGKSLDTINLSAHLDGFLSDKQTHELMDWSTSLSTTTIPQLTTLQLHGHLALSFDAPLLLELCPTLRHFSLAIKSYTSTSFVSTESARVLPRFMIPWEGKDLDEKEVQKFQLRVLELQGPWILTRRDMHQIGEQICGLVTLNLVGCRFYSSTTRRQVEILPDSGDDSSTFGGDDERDEGETDDNISSVERLVEKIQGTLRTLRIHRRGLEPKPRRDSYDYSSYSSIHSNATSPNLHCLANGSAVAVVAATAGPLEPVLAFKKRFPNVSLQIQEKQHEHSFVIAPSADILRRIHRPNSSQGRRSSLSLADIWDHAGPGPAQHQFGSRDSVWRRARDAMPFLKSFGEAARLVEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MS51</accession>
    <name>A0A9P6MS51_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">H+ nucleoside cotransporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_000460</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001098">
        <property type="protein sequence ID" value="KAG0011722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MS51"/>
    <dbReference type="OrthoDB" id="6075923at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005337">
        <property type="term" value="F:nucleoside transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008276">
        <property type="entry name" value="C_nuclsd_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011657">
        <property type="entry name" value="CNT_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002668">
        <property type="entry name" value="CNT_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011642">
        <property type="entry name" value="Gate_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10590">
        <property type="entry name" value="SODIUM/NUCLEOSIDE COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10590:SF4">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 28 MEMBER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07670">
        <property type="entry name" value="Gate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07662">
        <property type="entry name" value="Nucleos_tra2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01773">
        <property type="entry name" value="Nucleos_tra2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="118"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="154"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="178"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="241"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="282"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="324"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="412"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="506"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="540"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="domain" description="Concentrative nucleoside transporter N-terminal" evidence="8">
        <location>
            <begin position="159"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleoside transporter/FeoB GTPase Gate" evidence="10">
        <location>
            <begin position="250"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="domain" description="Concentrative nucleoside transporter C-terminal" evidence="9">
        <location>
            <begin position="353"/>
            <end position="558"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0011722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="561" mass="60701" checksum="211DBE484A62C080" modified="2023-09-13" version="1">MSVKDEKIDIDGEGQTHVSERQMEEVESDDDAFSQRSYHGRFGFYHRHSYLFGHLIFLIICIGLFVPAVIIHKEGNILVISLLFAAAVWWTAVRLLPDGTISKPIVIVWDTGARFVNWLPSIVVKAIGYGIPPVALILTAALRPDDDHGTRGQRLISCLGLVVLLFITWIFSKNHKAVAWKIVWTGIFMQYILGLLIIRWSVGYNIFQFISQQAENFLGYAQQGHDFVFGENSLTLPDGTVVAFASSFAVSVLPAIILFASIIQLLYYYNIVQTVVAKMASLVIHIIDISGVECVAACAAPFVGMSEASMLVGPFVSEMTDAELHQVLTSGFATISGSVFLGLLSFGADATALLTCCMMSVPCAVVVSKIRFPEEEEPLTKGSAVAPAYKDRESNAIHAISNGAIFGIKLCIVIIAVLLAVISILGLVNGFMGWIFSFYGVEISIQRIASWVLYPLAWLIGIPSSELSPAAEAMGIKFIINEFAAFSQFTAIQGTLKPRTALLTTYAMASFANIGSIGTQISLFLTLAPDRADAIARLSLSSCLCGAISTLISACVAGIVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MS73</accession>
    <name>A0A9P6MS73_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_000444</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PA-phosphatase related phosphoesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001092">
        <property type="protein sequence ID" value="KAG0011759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MS73"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008195">
        <property type="term" value="F:phosphatidate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046839">
        <property type="term" value="P:phospholipid dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006644">
        <property type="term" value="P:phospholipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03390">
        <property type="entry name" value="PAP2_containing_1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.144.10">
        <property type="entry name" value="Phosphatidic acid phosphatase type 2/haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043216">
        <property type="entry name" value="PAP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="PAP2/HPO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="PAP2/HPO_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10165">
        <property type="entry name" value="LIPID PHOSPHATE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10165:SF35">
        <property type="entry name" value="RE23632P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00014">
        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="Acid phosphatase/Vanadium-dependent haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="117"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="146"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="178"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatidic acid phosphatase type 2/haloperoxidase" evidence="7">
        <location>
            <begin position="43"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0011759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="274" mass="30370" checksum="318A5A4A5E754EFF" modified="2023-09-13" version="1">MFPYAEKETITTWALALIAVVFPVVVIAVIGLGVRRSPYDFHNGILGLLVSVLLTTIFTQVIKVTVGKHRPDFLSRCQPMLNGAPLTQDEPLHLWTIDVCSQTDHAILKDGFRSFPSGHASTSFAGLFYISLWLGGKMHPFDRRGYSLKVVVLVIPVVAALMVAISRVQDYRHAAIDVTWGSIIGIIFAILAYHQYYPSITAARSHVPHPPRDFSYLIRDSEGNTHEAGNFERVTGIQPNDTFVDETRNSSVEMTIANARQDSPNKSQDASHLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSK2</accession>
    <name>A0A9P6MSK2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_000674</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001144">
        <property type="protein sequence ID" value="KAG0011462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSK2"/>
    <dbReference type="OrthoDB" id="10029326at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050562">
        <property type="entry name" value="FAD_mOase_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356:SF2">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356">
        <property type="entry name" value="FAD-DEPENDENT MONOOXYGENASE ASQG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="7">
        <location>
            <begin position="20"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="7">
        <location>
            <begin position="296"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="439"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0011462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="461" mass="51717" checksum="63BA0342CAE106D6" modified="2023-09-13" version="1">MENIYPSQPPPVCRDGKTPHVMIVGAGIAGLFLAILLDRINVPYEIYERSDEARPLGGIMSLNSNIMPALEQLGVLDDLRKISLPSRDFNIYTSNMEEIGVLGGDDKLFEMSRFYDLLFSRLPAEKIHYKKRVMSIAYNKEGAMIRCSDGTTYHGDILVGADGTYSGVRQSLYKLMQSNGQLPDSDTKALSKCNICMVGTTDPLDPEKYPGISGPTAVLYQMIGEGTPYTWSSMSIPNNQICWSVVKQLGSEESEDERFRNSEWGPESNEAMISEVRDLRIPTGTLGDLIDATPREYISRVFLEDKLFETWHDGRTVLIGDACHKMLPSSGQGAVNAMQDAVILANCIYELKSIAENDVAEAFRDYKEQRYSRAKGQYEASQASAKLLYGQTFFERLLRKFVFNYMPKSIQRMSMVKDLAYRPQASFLPQVPKRGALDVLPQKPSKRYQEEQELAGAPKPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSN2</accession>
    <name>A0A9P6MSN2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Sorting nexin MVP1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Sorting nexin mvp1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="primary">MVP1_1</name>
        <name evidence="19" type="ORF">BGZ80_000235</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for vacuolar protein sorting.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the sorting nexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001042">
        <property type="protein sequence ID" value="KAG0012056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSN2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032266">
        <property type="term" value="F:phosphatidylinositol-3-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06866">
        <property type="entry name" value="PX_SNX8_Mvp1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01786">
        <property type="entry name" value="RA_STE50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00174">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1520.10:FF:000042">
        <property type="entry name" value="Sorting nexin mvp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000159">
        <property type="entry name" value="RA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028662">
        <property type="entry name" value="SNX8/Mvp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035704">
        <property type="entry name" value="SNX8/Mvp1_PX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045734">
        <property type="entry name" value="Snx8_BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47554">
        <property type="entry name" value="SORTING NEXIN MVP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47554:SF1">
        <property type="entry name" value="SORTING NEXIN MVP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00788">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07647">
        <property type="entry name" value="SAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19566">
        <property type="entry name" value="Snx8_BAR_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00314">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00454">
        <property type="entry name" value="SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50200">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50105">
        <property type="entry name" value="SAM_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SAM" evidence="16">
        <location>
            <begin position="7"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-associating" evidence="18">
        <location>
            <begin position="236"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="15">
        <location>
            <begin position="472"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="domain" description="PX" evidence="17">
        <location>
            <begin position="803"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="174"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="391"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="723"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="767"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="99"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="1070"/>
            <end position="1131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="174"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="393"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="412"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="447"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="728"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="772"/>
            <end position="789"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00072009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAG0012056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1193" mass="132272" checksum="E59775B2B3F107F3" modified="2023-09-13" version="1">MESITQWDPNRVHQWLSSIGFPNYEKQIKDNAISGDLLIHLDHAALKDLSIWEVGKRLVILKAIYQLKVSYGISLEAGDYVPPSVAFENEYNYQAAASLKSVEQAMHEKDNTIQHLVREVERMSKDLTKVKDELWIMQKDQKPLPEPSPGYPKAVNGQSSSILSASQTTHIGNSALTPQSPIHASHGMNSIRSPVYPPDSGFHSVPSSPHSPADVRTRGANMDANEDGKAVNSPDGAGAIKVYGQKPSSSTRDPVDAFRSFRISQDDPCYKVLPAALKKYKINDDWRQYALFICYGNTERILTYNEKPLLLMKQLKENNESPVFMLKHIKQMKSPAVNAPSLPNSFPPRKSTDLMNKELPMPPEFIAGGASGSSSTLGNLGSSSVSTLVNGNINPSLHRSGTTASMRTSSKTGTNPSTLTTPTIMGPVSMPTIPPSAATVNSLNPKSEASSSQLSSAVVGPKPENHVQETVEASGTAVALYEWEAKRDDELNVKVGDVFRIKSKGHGWWIVQRDDEIGWIPASILSESNSEDGYFSAEGVAIFDFTKTGPNELSIKTGDKLKIFRRHQHWLLATCEGQRGAAEENDDGMTASFSASTFDSEVNDPWTGTSQGMSPADLSTILSGMPLPAIYTTAFDLAQPSGGKVTVLAVNKIMSVSGLPPATISKIINMVVDPTRSRVTKGECSVALALVAMAQKNMNLSIENLTAHREDLPIPHLPGLESIDFGSTRESSTMYSTSTMPRHHPVNVGSSISDPWRNSTYRGSGYPPPPSYLASPPISSTESPSSQDPEAARKETIQWFLNLDTIHISFAPEKEGIFLFKHTNYIVESKNRQTTVIRRYSDFWWLLEILGKRFPFRILPNLPPKRLGVADEAFLERRLRGLTRFMNALMRHPVLRNDPLVISFLTEPVELALWRKNVVISTEDEFTSQLPISESLAKQVPLDLELQLESIKRRLPASIDYYRNIVHVMDRIQKRTEATATDYMRFSLAVNALADCEKHCHVEDCYNCGQLSQGYSKIGTHISQVSNFLDEQAKATQRGMVEDLKRHRDLLVSVKELLQRRDRLREAGTIETLEKRIATNEAKLKTLTTSAAAAATGDSNAGEPGAYDAQIERITNHCNSDRAELENQKQRSVLLHHTLWMEITYFHKNHALIATMYQNFVNEQIKTSQNLNDSWKSLSPIVHDLPMEVNGFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MT59</accession>
    <name>A0A9P6MT59_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADH:ubiquinone oxidoreductase-like 20kDa subunit domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_011546</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the complex I 20 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000940">
        <property type="protein sequence ID" value="KAG0012743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MT59"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045271">
        <property type="term" value="C:respiratory chain complex I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009060">
        <property type="term" value="P:aerobic respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015990">
        <property type="term" value="P:electron transport coupled proton transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032981">
        <property type="term" value="P:mitochondrial respiratory chain complex I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12280:FF:000001">
        <property type="entry name" value="NADH-quinone oxidoreductase subunit B 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01356">
        <property type="entry name" value="NDH1_NuoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006137">
        <property type="entry name" value="NADH_UbQ_OxRdtase-like_20kDa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006138">
        <property type="entry name" value="NADH_UQ_OxRdtase_20Kd_su"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01957">
        <property type="entry name" value="nuoB_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005012">
        <property type="entry name" value="PRK06411.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11995">
        <property type="entry name" value="NADH DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11995:SF14">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 7, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01058">
        <property type="entry name" value="Oxidored_q6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56770">
        <property type="entry name" value="HydA/Nqo6-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01150">
        <property type="entry name" value="COMPLEX1_20K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 3" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:ubiquinone oxidoreductase-like 20kDa subunit" evidence="4">
        <location>
            <begin position="113"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0012743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="238" mass="26307" checksum="8813B8C514AD3B8A" modified="2023-09-13" version="1">MLSTVGLRASIVSAAARSSLKPIATQQIRHFGLLSEKDEQGADIILRLERKETATTAAAPVQSRNMSTAVSKSYPGPIHQPANAVEYALSTVDKIINWGREGSIWPMTFGLACCAVEMMHMAAGRYDQDRLGIVFRASPRQSDVMIVAGTLTNKMAPALRKVYDQMPEPRWVISMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPGCPPTSEALLYGVLQLQKKMRRSRVTTMWYRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTG2</accession>
    <name>A0A9P6MTG2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ADP-ribosylation factor GTPase activating protein, ER-Golgi transport</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">GLO3_2</name>
        <name evidence="8" type="ORF">BGZ80_011558</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000944">
        <property type="protein sequence ID" value="KAG0012722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTG2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048205">
        <property type="term" value="P:COPI coating of Golgi vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08831">
        <property type="entry name" value="ArfGap_ArfGap2_3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.150">
        <property type="entry name" value="Arf GTPase activating protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037278">
        <property type="entry name" value="ARFGAP/RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001164">
        <property type="entry name" value="ArfGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038508">
        <property type="entry name" value="ArfGAP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45686:SF4">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR GTPASE ACTIVATING PROTEIN 3, ISOFORM H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45686">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR GTPASE ACTIVATING PROTEIN 3, ISOFORM H-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01412">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00405">
        <property type="entry name" value="REVINTRACTNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00105">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57863">
        <property type="entry name" value="ArfGap/RecO-like zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50115">
        <property type="entry name" value="ARFGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Arf-GAP" evidence="7">
        <location>
            <begin position="10"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="163"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="255"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="163"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="188"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="201"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="255"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="275"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="292"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="311"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="332"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0012722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="460" mass="49826" checksum="248AF5EB3248FA84" modified="2023-09-13" version="1">MAEPTKQEIQDVFKKLSLQRANKNCFDCHASIDQNCWTSIPFGIFLCTDCGALHRSFGTHVSFVRSTVLDKWTWEQLRTMTVGGNAAAREYFSKQPGVDSKDAKTKYSSKIGTAYKEKLAQKVKEDMLANPGKLSIDHHTEDANKFAAAALTTSCSDDDFFNNWNQPKKAAPTSSQQTNAPPTIGFGATASRTSTTASRPVKSTLTSVRKTGTASKPMKLGARKAEGISFEEAEARAKAEAERIEKLGFEAAEEERLQKSAAEKAREEAARAPQGTASSNVRSNYYQANTAEKSRTSSEDLERLGMGMGRMGITTTTPATKPASTRMGFGSMGNSSNYSPQVEENVTAAREKFGNQKAISSDQYFGRGTYDADAQAEASSRLQSFSGATSISSNQYFGRPDESPTIGSDVSLSSFGNISGSDLAKKLGQADLTTIKNAVQMGAGKLSDMLQDMQAKYNYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTK5</accession>
    <name>A0A9P6MTK5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Proteasome subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">PRE1</name>
        <name evidence="6" type="ORF">BGZ80_011468</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the proteasome complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the peptidase T1B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000924">
        <property type="protein sequence ID" value="KAG0012863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTK5"/>
    <dbReference type="OrthoDB" id="268428at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005839">
        <property type="term" value="C:proteasome core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010498">
        <property type="term" value="P:proteasomal protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03758">
        <property type="entry name" value="proteasome_beta_type_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000008">
        <property type="entry name" value="Proteasome subunit beta type-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035206">
        <property type="entry name" value="Proteasome_beta2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="METALLOPROTEASE TLDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194:SF2">
        <property type="entry name" value="PROTEASOME SUBUNIT BETA TYPE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 5 6" id="KW-0647">Proteasome</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00026071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0012863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="194" mass="21878" checksum="CC3A2E6F85D01FD6" modified="2023-09-13" version="1">METLFGITGKDFVITAYDSKAVASITLMKIGEDKSRELNSHSLMLFSGEPGDGVHFSEYIERNIKLYGIRNGIELSPKAVASFARRELADSLRSRKPYSVNLLIAGFDVKTNRPALYWLDHLASMVDVPFAAHGYGAYYCLSLLDRYHREDITEEEGIKLLQKCIGELRSRMILNMPDFVAKVVNKDGIRIVQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MU11</accession>
    <name>A0A9P6MU11_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">FAL1</name>
        <name evidence="16" type="ORF">BGZ80_011551</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the DEAD box helicase family. DDX48/FAL1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010000942">
        <property type="protein sequence ID" value="KAG0012733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MU11"/>
    <dbReference type="OrthoDB" id="10265785at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18045">
        <property type="entry name" value="DEADc_EIF4AIII_DDX48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000031">
        <property type="entry name" value="Eukaryotic initiation factor 4A-III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000498">
        <property type="entry name" value="Eukaryotic initiation factor 4A-III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 12 16" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="15">
        <location>
            <begin position="24"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="13">
        <location>
            <begin position="55"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="14">
        <location>
            <begin position="236"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="11">
        <location>
            <begin position="24"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00037945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0012733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="397" mass="45260" checksum="D2C082A3E183BCD5" modified="2023-09-13" version="1">MSGINRKHDDKLVFETSEDVKVVPTFDSLGLKDDLLRGVYAYNFERPSAIQQRAINPIVKGRDVIAQAQSGTGKTATFSISILQSIDTSIRETQALVLAPTRELAIQIQSVILALGDYMNVQCHACIGGTSIGEDIRQLDHGQHVVVGTPGRVFDMIRRRNLRTRNIKMMVLDEADELLNMGFKDQIYNVYRYLPPSTQVVILSATLPHDVLEMTSKFMTDPIRILVKRDEITLEGIKQFFVAVEKEDWKFDTLCDLYDTLTITQAVIFCNTRRKVDWLTTKMREANFTVSSMHGEMPQKERDAIMQEFRQGASRVLITTDVWARGIDVQQVSLVVNYDLPSNRENYIHRIGRSGRFGRKGVAINFVTQDDIKILRDIEQYYSTQIDEMPMNVTDLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MU21</accession>
    <name>A0A9P6MU21_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Peroxisomal membrane signal receptor PTS1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">PEX5_2</name>
        <name evidence="10" type="ORF">BGZ80_011786</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peroxisomal targeting signal receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000992">
        <property type="protein sequence ID" value="KAG0012383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MU21"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005052">
        <property type="term" value="F:peroxisome matrix targeting signal-1 binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016560">
        <property type="term" value="P:protein import into peroxisome matrix, docking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024111">
        <property type="entry name" value="PEX5/PEX5L"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056413">
        <property type="entry name" value="TPR_CcmH_CycH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10130:SF0">
        <property type="entry name" value="GH08708P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10130">
        <property type="entry name" value="PEROXISOMAL TARGETING SIGNAL 1 RECEPTOR PEX5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23914">
        <property type="entry name" value="TPR_CcmH_CycH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50293">
        <property type="entry name" value="TPR_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="10" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 8" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="Cytochrome c-type biogenesis protein H TPR" evidence="9">
        <location>
            <begin position="195"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="8">
        <location>
            <begin position="213"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="8">
        <location>
            <begin position="320"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="8">
        <location>
            <begin position="354"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF23914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0012383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="471" mass="52232" checksum="C6084EDA6A7E7F32" modified="2023-09-13" version="1">MAPGGDWTQEFQDHRPPGARVFELSPEEEAAFSQAFQQHQAPPHEWQQEFMKHEHIVGDMPPEFEASFQKNFDWANEFALVEGKGKGKALDNASWEAQFEAAQRDGEASTANPINFEDKEQLEDLWNTLRDNLTDTEDVQNILDDPSSWENEFSDLSSIAAPQLGPYTFETNNPYLTHPDPMAEGIRLTEQGGSLSEAALAFEAAVQQDENNSRAWMMLGNVQAQNEKEEPAIRALEKAVQIDPNNLDAYMNLAVSYTNEGYDHQAYVTLEKWLATKYPDVVSANPAPANAISSWETHARVTDLYLQAVRNAPAGAEMDADLQVGLGVLFYGSGEYEKAVDCFVAGLKARPGDYLLWNRLGATLANSGRSEDAIEAYHKALEIKPSFVRARYNLGVSCINIGCHKEAAEHLLGALSMHQADGDGNGGGSVNVSGNLWETLRRTFMMMDRSDLAERAVVGADINQFRGEFEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUN6</accession>
    <name>A0A9P6MUN6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">PRP22_2</name>
        <name evidence="11" type="ORF">BGZ80_011119</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="JAAAID010000855">
        <property type="protein sequence ID" value="KAG0013365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUN6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000390">
        <property type="term" value="P:spliceosomal complex disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17917">
        <property type="entry name" value="DEXHc_RHA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000615">
        <property type="entry name" value="pre-mRNA-splicing factor ATP-dependent RNA helicase DEAH7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF85">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DHX8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="24"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="213"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="562"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="729"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="562"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="585"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="752"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="772"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0013365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="782" mass="87942" checksum="1797CF11093120BC" modified="2023-09-13" version="1" fragment="single">MSSRNEIRRQQEALPIFDHRDALMDAIRNEDILIIVGEPGSGKTTQLPRYLIEEFKDMRIGVTQPRRIAAISVSKRVAEEYDCKLGDTVGYAIRFDDNTTSRTRLKYMTDGVLLREATMDPLLEKYDLIIIDEAHERSVETDVLFGLLKRTRAKRPNLKLLIMSATLDVMKFSDYFDSCSIYTIKGRAYPVEILHSRNTNKLGAQKSGYAAKSVETVMHILDKEIRPDEVGDILVFLTGQHEIERACQDLKTAVLEREREYKESSSAKSNNGSNRPVSLDQLQILPLYASLDLLDQTAIFGPTPRNSRKIIFATNIAQTSVTIPNIRFVVDSGFVKQKMYDPSTGMDALLVVPISKAAATQRAGRAGRTRAGVCFRLYSRESFETEMDEETVPEIKRTGLTGTVLSLKRLGIVDVNGFEFLDRPGDEELSAALRELYLIGGIDQHGRMTDIGHGMVAYPVSPLLARSLIEAEKIGCLDNAITIVAMLSVEEPFHLPRKEEEHDVATAAHAAFYHRSGDHMTLLNIFEAWREARYSKEWCRDNYFNIRQLRLAKSIRSQLQDIVDRNASRDKGSKKQNTKDRQSRHQSPAPSNAGHSNEKPSSQSSSSSRSLLQAFSQGYGIHLSKKHIHRQMFYHYLASTFSSSGAGGASASSLLALHISPLSALYLDDERSMTKHGRKVSADLEWIFYHEVVYHAKAVMRYVSKTDVRWVQDIMDRAKIYDRGQVWLNGGQSSEESGEEHDKTKGGDDGSIVSSTNKRELTGTSVADESDEQAKKRARLEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MV57</accession>
    <name>A0A9P6MV57_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_010147</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000677">
        <property type="protein sequence ID" value="KAG0014925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MV57"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0014925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="389" mass="41881" checksum="97F48FA0177848B5" modified="2023-09-13" version="1">MSAKHIAAVKDASKKNKGGPKGGSGQKGPSPNASKKLPKDDEDQDPPEVVEALTTFRKAEKAAKENPGMAASVLWKIAKALWTFRQSLETAKVLSLLIRILSELQATTGTAPSVTGVATAQGSLSPTQISMTLYLSRLAMARLFVYQSPELASQYYLDAIQGRWQIDHADLQTINEMVNTSSVTQLLDHCRTFLSTHPKTEKLMVVSAPSASGDTAAKKPADPNLKLLVIFLESASMLAQKNATVPLKSSQKTIVSTVDRIQGETALACYAMAAVLTEASGDKAGTAAILRTMETGDFVRMQTTISLLNSCCDMAKYQDVQTVAEVANAVISQDNDYLYNGASWALEHLMLLIQENREDGGSRANLLLCRHSTPAASVETLTRVHQLVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MW04</accession>
    <name>A0A9P6MW04_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="18">Kinesin motor protein cin8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">CIN8</name>
        <name evidence="18" type="ORF">BGZ80_010474</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-5/BimC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000731">
        <property type="protein sequence ID" value="KAG0014391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072686">
        <property type="term" value="C:mitotic spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005876">
        <property type="term" value="C:spindle microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008574">
        <property type="term" value="F:plus-end-directed microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000073">
        <property type="term" value="P:initial mitotic spindle pole body separation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01364">
        <property type="entry name" value="KISc_BimC_Eg5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.850.10:FF:000051">
        <property type="entry name" value="Kinesin-like protein bimC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047149">
        <property type="entry name" value="KIF11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047241">
        <property type="entry name" value="KIF11-like_kin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025901">
        <property type="entry name" value="Kinesin-assoc_MT-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47970:SF12">
        <property type="entry name" value="KINESIN FAMILY MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47970">
        <property type="entry name" value="KINESIN-LIKE PROTEIN KIF11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13931">
        <property type="entry name" value="Microtub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="9 15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="7" id="KW-0498">Mitosis</keyword>
    <keyword evidence="10 14" id="KW-0505">Motor protein</keyword>
    <keyword evidence="6 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="17">
        <location>
            <begin position="100"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1058"/>
            <end position="1100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1112"/>
            <end position="1155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1252"/>
            <end position="1295"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="492"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="774"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="47"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="71"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="1125"/>
            <end position="1145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="1260"/>
            <end position="1273"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="183"/>
            <end position="190"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00034704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAG0014391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1295" mass="143139" checksum="E828B455E8021D75" modified="2023-09-13" version="1">MFGARNGASRPPSALANHKTLSQQGSSHKLTEDDSMSTGVIRRKASSDSLSSNGSMNTTAAIARASATASHQSQQNPSTLRLNGQPNHQTNAQTANKELNIQVVVRIRSRSEREVKENSPVAVQAQNKEILVPSTLGDRAPSKSYSFDRVFMYSDQECIYNEIVTPILDEVLTGYNCTIFAYGQTGTGKTFTMEGDLRDSFGECSRDAGIIPRTLYTLFAALERKNTEYTVRVSFLELYNEEVKDLLVPDDDRKVVKIFDSIKKQGPLVQGLEEVSVFNATQGIEALRKGSAKRTVASTKSNDKSSRSHGVFSITVHVKETADDGEELLKIGKLNLVDLAGSENIARSGAEATQAKEAGRINQSLLTLGRVINSLVERSQHIPYRESKLTRLLEDSLGGKTKTCIIATISPARSCLEETISTLNYANRAKNIKNTPEINQKMSKKTLIKEYLLEIDRLKADLNATREKNGVFMTHESYQALLDENSSNKDLVGETQKQVDKIVQELARVEEKFRENMKILTATEYKLGAANAELESKRVELQEVRDELTQTKQILQEEKILRQAHAHAENQLNSVAAGLRSTLAVSVKDIKGLHEKLDRKNEIERENRHALVEFQERLLNLTGELGERIQGFGISQGDLLAMAAQKIEKAFQEATAGVDSTQKCLASQLERMDKSLEAFNDLDSNTSGKALAFKQEFETLRLEMVEFLKSRVEISKTSALEGFSELKKALSEFTGSIEKHQATMTEKALGLIDESTKFSEDNISRQKRALESYEKATRSEIEFLAAQNQALRQQLRDQEVKKEEQKSLLLSNIGGMLDGFLSDQTNALMGHFSNSCDALEGSTARLNTAHSEQRSWTSEFERLGAQRIQGLVGLRSTFDNDSADVMARTNQDGKAVAKKTDILGSRIEDDLQSQQDFMQTRMFEMNAKAMSGYDQMQAQHIAMAKLFSQTSDHTIAALQDLRIRTNTANANVESVYQQTSNDFTTAKDQVRIFSDDAGENLSLTREETEALVPRRLKVDDSTGRTPARKKYKYPHTWERARPSRDLLKEFRELGRVHMLTTNQPADSRELSDSDDNVEEPLNKEQALETPSLQSPESEADNQLIRDVNELSADTESLGDDGVDIESSSQTTTESQPRSPSRRASQLHVRQEAEMEKENNAEFQLAAQGVNNIPRPSRPTRPGLVSAAASDFGLGKKMGMGHNTMHGKRSASEMEESNSIGNTMADIINNMHATTARPNPFLQKANGALAPGATVTTTSASSILPPSSGPFSGSGLFGAGKSGLTNSSEGPRKIRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXZ0</accession>
    <name>A0A9P6MXZ0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SF3 helicase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_007626</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000394">
        <property type="protein sequence ID" value="KAG0018035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXZ0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006500">
        <property type="entry name" value="Helicase_put_C_phage/plasmid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014015">
        <property type="entry name" value="Helicase_SF3_DNA-vir"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045455">
        <property type="entry name" value="NrS-1_pol-like_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051620">
        <property type="entry name" value="ORF904-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014818">
        <property type="entry name" value="Phage/plasmid_primase_P4_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01613">
        <property type="entry name" value="primase_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35372">
        <property type="entry name" value="ATP BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35372:SF2">
        <property type="entry name" value="SF3 HELICASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08706">
        <property type="entry name" value="D5_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19263">
        <property type="entry name" value="DUF5906"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51206">
        <property type="entry name" value="SF3_HELICASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SF3 helicase" evidence="4">
        <location>
            <begin position="150"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0018035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="429" mass="49195" checksum="C0852FDFBD172921" modified="2023-09-13" version="1">MAFNGLIWQELSAPYVLNDISDTCSAILEGLLRHICTPHNAKESQINIIQKQRKRFEVGRNFVRKSSNLRSILTYYRIMYTDETLETRLDQNPDILSVRNGIIDLQTGVIRNGAASDYMSQQLDILYHGLDAKTDIVDEFIGGLFNHDEDSITYLQRLLGYSITGRMDSQVWCMFTGKGSNGKSLLASLLEDLLENWVVTAPYEIFFRGDQRARDGSHSTHLGTLKGARICIKEEAEPKDKLNTETLKTATGGGSITMRGAYEREFETFKPMCLPILLCNHRPEVDITDEAMMRRIIVVPFNNIYTTPDDPKRPFNNANSAHRLRDPELKHRLLKQDARQQFVVWLVRGAVAWYRNKDLSQHPPAMLRAFQEYNDENDKLQQSIHNHCEVGVLHRVNATDFRTQYCKAMHASIMQIKLAELMHEKGFKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYD4</accession>
    <name>A0A9P6MYD4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FAD-binding FR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008186</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000437">
        <property type="protein sequence ID" value="KAG0017532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYD4"/>
    <dbReference type="OrthoDB" id="436496at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42815">
        <property type="entry name" value="FAD-BINDING, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G07600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42815:SF2">
        <property type="entry name" value="FAD-BINDING, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G07600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="1">
        <location>
            <begin position="370"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0017532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="673" mass="74818" checksum="4AAA0431374B8151" modified="2023-09-13" version="1">MTTLVQGSIVSLYDRWHSGERKIQDLMHVREAVQDMSSIMRPSLTTQMQEFVPGLNYFFIGTLDDQGRPWVSILTGPKGFLQSPNSKCLEIRTRITRHSEQTKDAADPIFFNLARGETFKSGKRMWGAVALDFSNRRRNKMNGVVYPDGLLTVDETSGELQLKLTVEQSIGNCPKYITIREMKAQTRSESTDSSNAENVTTALEMTGGSSLGIGDQEIAIIRQADCFFIASRFIDENLADQTSGMDCNHRGGNPGFVRLGEDNKSLVFPDYSGNRFFNTLGNIANDERVGILFISFETGDLLHITGRAKIFVGKGSQALYPHTQRCVQVTIDGHLLRNDAIPFRMHTRELSPYNPIVPSGQKRTIEENLDSRVSATLSRITKHTRDISTFHFNTSGPIRYSPGQYAVLDFSQFNTVGYRHMAPDDPQSLNDDYIRTWTISSAPLLGTLTAQGEGWQETSEFTMTIKRKPGGAVSNFLHNLPLESLSRPFTVPLVSTGGNFVFPGPTSNSITQSQSPVKFALISGGIGSTPFISMIRGAKQLQHGSIDIKWVNSVPYFEDSLPEILREIVEVPQVKTPSGTAELKTDQPLNLSIEVFLSRANPTSTPSTQLDAFQNVRFHFERLGTQALLATIPDLQDRDIFLCGPEPFMEATKGYLKELGVPLGRIQTEAFNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYJ0</accession>
    <name>A0A9P6MYJ0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Inosine-5'-monophosphate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">IMD1_2</name>
        <name evidence="3" type="ORF">BGZ80_006893</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IMPDH/GMPR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000343">
        <property type="protein sequence ID" value="KAG0018674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYJ0"/>
    <dbReference type="OrthoDB" id="416622at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003938">
        <property type="term" value="F:IMP dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006183">
        <property type="term" value="P:GTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000424">
        <property type="entry name" value="Inosine-5'-monophosphate dehydrogenase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005990">
        <property type="entry name" value="IMP_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001093">
        <property type="entry name" value="IMP_DH_GMPRt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11911:SF111">
        <property type="entry name" value="INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11911">
        <property type="entry name" value="INOSINE-5-MONOPHOSPHATE DEHYDROGENASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00478">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51412">
        <property type="entry name" value="Inosine monophosphate dehydrogenase (IMPDH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IMP dehydrogenase/GMP reductase" evidence="2">
        <location>
            <begin position="42"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0018674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="96" mass="10484" checksum="839AFF2EB702328C" modified="2023-09-13" version="1" fragment="single">MTAQAQYPDHALALQDLETAGTKSRRDGLSAEELMDSVTQGGLTYNDFLILPGYINFQANAVQLESKITKRITLKTPFLSSPMDTVTETDMAIAMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZ47</accession>
    <name>A0A9P6MZ47_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 11">Chitin synthase</fullName>
            <ecNumber evidence="2 11">2.4.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">CHS1_3</name>
        <name evidence="14" type="ORF">BGZ80_007004</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10 11">Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>[(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n) + UDP-N-acetyl-alpha-D-glucosamine = [(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n+1) + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16637"/>
            <dbReference type="Rhea" id="RHEA-COMP:9593"/>
            <dbReference type="Rhea" id="RHEA-COMP:9595"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17029"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="EC" id="2.4.1.16"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Cell membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the chitin synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.16" evidence="2 11"/>
    <dbReference type="EMBL" id="JAAAID010000351">
        <property type="protein sequence ID" value="KAG0018590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZ47"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030428">
        <property type="term" value="C:cell septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004100">
        <property type="term" value="F:chitin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006031">
        <property type="term" value="P:chitin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04190">
        <property type="entry name" value="Chitin_synth_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004835">
        <property type="entry name" value="Chitin_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013616">
        <property type="entry name" value="Chitin_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914:SF9">
        <property type="entry name" value="CHITIN SYNTHASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01644">
        <property type="entry name" value="Chitin_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08407">
        <property type="entry name" value="Chitin_synth_1N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="4 11" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="468"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="503"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="547"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="578"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="625"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="759"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="791"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin synthase N-terminal" evidence="13">
        <location>
            <begin position="84"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU366040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0018590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="826" mass="93945" checksum="C5304EABD55B01B9" modified="2023-09-13" version="1">MAQYVQLRDFPQQEQEQPYQQQQQQQQLQPPYGGATPYLDHNMPYGAATPNLGHAAYPSVETPFLPNSTVRYGEAPERQERRYKTTKNVELTNGNLILDCPVPTHYLKNQRRQEGDEWQYMRYSAVTCDPNDFKNEGYTLRPAMWNRETELFIVVTMYNENEILFAETMHGIIKNIRHLVSRTNSRTWGDRTWEKVVVCIVADGRKKCNEKVYNYLSALGVYQEGVAKREVNGKDVEAHIFEYTTQVTIDPTMKIVESKTSDYAPVQIMFCLKEKNAKKLNSHRWFFNAFGPILDPRVCVLLDVGTRPGPTSIYQLWKVFDLNSNVAGACGEIKPVKGPAAKNLLNPLVAAQNFEYKMNNILDKPLESVIGYIQVLPGAFSAYRYRALLSPPETPNEGPLVSYFKGEKPSADSGIFDANMYLAEDRILCFELVAKKNYAWTLRFVKAAWAETDVPDTVPELISQRRRWLNGTFFVAIFSIVHFGKIYQSDHATWRKALFHLQLVYNVISIMFSWFALANVYLTFYILANSLTISGNSPFGDNGVAKVLSVILDYVYEFLVIVMFVLSMGNRPTGSKVLYITAMIFFAFLMFYMTFAAIWLTKLGIETAVEGGATSFSAILADPNFSTIILSLASTYGLYLFTSIIYLEPWHMFTSFIQYLCMVPSFVNVLNVYAFCNTHDVSWGTKGDTIEKMDLGAVKATSDAKTAEVTVNVPVEEKDINDNYQTAMDSLTDHKEPEPPKPDLKQEQEDYYRAFRTRLVLVWCATNALLVSVISYGGGSMTETYVLRSKAYLGFVLWSVAFLSLFRFLGSAAYVILRLISGELRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZJ5</accession>
    <name>A0A9P6MZJ5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_007047</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000354">
        <property type="protein sequence ID" value="KAG0018539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZJ5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040202062" evidence="3">
        <location>
            <begin position="24"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0018539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="330" mass="33840" checksum="1EC559554C567E55" modified="2023-09-13" version="1">MHFKKSSLVFLALVLALSTSVSAQDALDAVLPAADTTDAGATSTSTAAATTATTTVSPTTTADATTTSTTIPTTESTTVTTASTTVPATTTDSPQKTTTRAFTTTTTITTLNSTMTTTTATPSATNSSSDSSSGTKLATAGIVIGSIVVAAAIGIWVFRKWKLSPSRDFQSKIRGDEYQDYPRPYENDAVFLRNLDQPSEPAPTKSSPYSAPGSLPAEDQYYDPNYTNDQTAYAHHDGYAGYDQSGYDQAGYDHQGYGHGYDNNYGGHGDYAESQVGGGYAASNVGGGYAASNVGGGYAASNVGGGYAASNVGGGYAASNVGGGYQHQGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N060</accession>
    <name>A0A9P6N060_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PCI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006417</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000317">
        <property type="protein sequence ID" value="KAG0019016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N060"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070390">
        <property type="term" value="C:transcription export complex 2"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016973">
        <property type="term" value="P:poly(A)+ mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000973">
        <property type="term" value="P:post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045114">
        <property type="entry name" value="Csn12-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12732:SF8">
        <property type="entry name" value="NUCLEAR MRNA EXPORT PROTEIN THP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12732">
        <property type="entry name" value="UNCHARACTERIZED PROTEASOME COMPONENT REGION PCI-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00753">
        <property type="entry name" value="PAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="1">
        <location>
            <begin position="218"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0019016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="432" mass="49729" checksum="287523E4D91F1498" modified="2023-09-13" version="1">MQDIRVFIRRTVEAFNRKDRNSICELIILDEGNPDLRQLHETLFEMTDDSIRSTVRDQTKDSPRQLKDFITNYLVFTIASGLDSSSLVDVYELLSTCYGSFLSLYTAHDAQWLTPLLMNLSYSLVEWAVYADEERPQAKELKISDAFGKHLSKALNIIISDKSSNELGDSKKMALYYVANLSFRVHFKLRSTRLMPTMMANISKAGVNLSDFPMSQQVTHRYYLGRYLLYQLDLRRSEKHLKFAFNNCPGPSQDESENMVTFKNSRLALLYLTACRLCLGSMPSLQLLQAYNLDTYFQPLVTAVKSGDLSLLQRSLSSPELRSWFVRKEIYFLLGEKLTVLCWRSLIRRTCLVSRRPTEPQMRVQLEALLSVARALTKDDTYDIFDVECITASLLDQGYIKGYIHSQKKILVLGKSNPFPTVWNVEVMEEVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0X0</accession>
    <name>A0A9P6N0X0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_004074</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the perilipin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000212">
        <property type="protein sequence ID" value="KAG0020513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0X0"/>
    <dbReference type="OrthoDB" id="376826at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019915">
        <property type="term" value="P:lipid storage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010890">
        <property type="term" value="P:positive regulation of triglyceride storage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004279">
        <property type="entry name" value="Perilipin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14024:SF49">
        <property type="entry name" value="LIPID STORAGE DROPLETS SURFACE-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14024">
        <property type="entry name" value="PERILIPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03036">
        <property type="entry name" value="Perilipin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="26"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="38"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0020513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="466" mass="50493" checksum="7C13FD84CBCE0A48" modified="2023-09-13" version="1">MTTPYSESNNTEVDNRSTSSSTVHSELIKGPDGRTVRKITTTTTTRTKVAGDSQTQEKEEEPAQAGFIARVSSLPLIHDSVSTLTSIAKDNKYSRYALDTAGSAVDTVNKYTEGYQKTVQPITSKVDQIASKSLDILETTFPIVTKPTSEIVTQVKKPIVYVEESSKNAYTQIQSTIDTHVTAPVKTVASNIASTAATTRDQITTAATATATNIATTVNTHATPLVDGLETVVNRYLPDSEVEQTTANQSNQAARVVDLTRNVSLRVSRRVSVGVAPITQSAQDLRKAAENNATLVKSKESIQALNLRLTTLLESIRLHAKELQENVQKAPGEASQRVQTLSASLLAEIDSLSAYLKEHSPKLPEYVQVRLEPLVGFINERYVVVKGEIVKPDVSAIQKARNILHLTTEETLPILQNAAQDVKESLLQYQSTLQENVQRGLAKVQEVNSSVSGAATRAVNTLVGAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0X9</accession>
    <name>A0A9P6N0X9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_004028</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000210">
        <property type="protein sequence ID" value="KAG0020541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0X9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031410">
        <property type="term" value="C:cytoplasmic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097320">
        <property type="term" value="P:plasma membrane tubulation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019497">
        <property type="entry name" value="Sorting_nexin_WASP-bd-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45827">
        <property type="entry name" value="SORTING NEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45827:SF1">
        <property type="entry name" value="SORTING NEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10456">
        <property type="entry name" value="BAR_3_WASP_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14604">
        <property type="entry name" value="SH3_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="75"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="PX" evidence="5">
        <location>
            <begin position="293"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="46"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="140"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="199"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="47"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="58"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="140"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="200"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="233"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0020541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="692" mass="77471" checksum="72CD594F1C39FB58" modified="2023-09-13" version="1">MISSAPAIPKIHPIFSTQPQTLTTLEEGDIDVEYKDGAFSIDAAIAQQKPQQQQQQQSGKDLSSGEHTPQQQPPPHGWTVRALYDFEGQPEFSELSFSAGDVLTVVKVGLAEGWSLAEKDGIRGLVPEAYVTYIHDFSASPDNNGGHTQQPSNASAYSGYSTATATASTNPRNSVFGKRQLNRFSWFVTTGVEEFLLTGGASNNATNSTEQGQSADTESRRLSSVRDLLEKSPPNSGGSMKYQHQPQGPGSSVRSHSGGDKIVEDSDDDEEVTESDKHYIQSGPSWQEKAPLFKVRVHDPETRRKMVGMQEYTLFQVTSTFTQGVSVTVERRYSQFEWLYERLVKKFGALILPPLPEKQYAGKSNDDGDWKRAEKKFDNDRITGTAFFQHVFHPDFNVNEDGDIDLVERFNAHCKGTERLMPFLMDATMAYKEGISDSQFRYKRFGLALLNLISTTKDGPENQTLNDGLAWCWRENCADCLRLTKAMQTTAETMQLMADVHQTHITEGCLPWQETIKENATPASTFVPLVDMHTGTHKKLVEVFEKEQTMEEIDSETVKSRCDTVFNITLAEIDRVHDERVQDFQKGTKEFLDSQIAYHEKMLAHLKQARAGFDEPYYNNLSNTPRFRSRYEKDLEDQRYQSQKPSRPVSAASVASVSNMVGGVVDGVGFMNGLLKNKTRASAGRSIMGFWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N124</accession>
    <name>A0A9P6N124_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Acid phosphatase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_005068</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000252">
        <property type="protein sequence ID" value="KAG0019917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N124"/>
    <dbReference type="OrthoDB" id="5135119at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009395">
        <property type="term" value="P:phospholipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007312">
        <property type="entry name" value="Phosphoesterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31956:SF8">
        <property type="entry name" value="ACID PHOSPHATASE PHOA (AFU_ORTHOLOGUE AFUA_1G03570)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31956">
        <property type="entry name" value="NON-SPECIFIC PHOSPHOLIPASE C4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04185">
        <property type="entry name" value="Phosphoesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040357690" description="Acid phosphatase" evidence="2">
        <location>
            <begin position="20"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0019917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="355" mass="38613" checksum="DC430175FDDB45B9" modified="2023-09-13" version="1">MVKFTSPLVLLAATALASAAPKGKWFDSIGIIMAENEDFLLTIQQLPYQALISQGLLATNYFGLSHTSEQNYAAILTGVLDPNIYRGDASTPANLNITYPTILDQLKANGLTYKQYTESYPGGCYLADMYPDDPVTALYYKRHSPFNMVSALRGTPECTTAIGTYDDFAKDVASGSLPNYFWIIPNDLHNTHTADTSPNPFVDADPWTATEGPKWLAAAQKANALFINTWDESRCDNQKYPCGDHKDQQIATILWGPMVQKNTTSDKYWNHFSIARTVEDNWGLKPLSTADANATAFDFLMANPSNDTSSSSGSNNGAGSGRTHPNVATSLVKASIDPVLMGAMVGLLSVFYSAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1H0</accession>
    <name>A0A9P6N1H0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">AP-2 complex subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_003868</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <location evidence="1">Coated pit</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the adaptor complexes large subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000205">
        <property type="protein sequence ID" value="KAG0020642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1H0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030122">
        <property type="term" value="C:AP-2 adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035615">
        <property type="term" value="F:clathrin adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072583">
        <property type="term" value="P:clathrin-dependent endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000020">
        <property type="entry name" value="AP-2 complex subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.10">
        <property type="entry name" value="TATA-Binding Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050840">
        <property type="entry name" value="Adaptor_Complx_Large_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017104">
        <property type="entry name" value="AP2_complex_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003164">
        <property type="entry name" value="Clathrin_a-adaptin_app_sub_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008152">
        <property type="entry name" value="Clathrin_a/b/g-adaptin_app_Ig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013041">
        <property type="entry name" value="Clathrin_app_Ig-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009028">
        <property type="entry name" value="Coatomer/calthrin_app_sub_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012295">
        <property type="entry name" value="TBP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22780">
        <property type="entry name" value="ADAPTIN, ALPHA/GAMMA/EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02296">
        <property type="entry name" value="Alpha_adaptin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02883">
        <property type="entry name" value="Alpha_adaptinC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037091">
        <property type="entry name" value="AP2_complex_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00809">
        <property type="entry name" value="Alpha_adaptinC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49348">
        <property type="entry name" value="Clathrin adaptor appendage domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55711">
        <property type="entry name" value="Subdomain of clathrin and coatomer appendage domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0168">Coated pit</keyword>
    <keyword evidence="3 7" id="KW-0254">Endocytosis</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Clathrin adaptor alpha/beta/gamma-adaptin appendage Ig-like subdomain" evidence="9">
        <location>
            <begin position="684"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="4"/>
            <end position="5"/>
        </location>
        <ligand>
            <name>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate)</name>
            <dbReference type="ChEBI" id="CHEBI:57836"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate)</name>
            <dbReference type="ChEBI" id="CHEBI:57836"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate)</name>
            <dbReference type="ChEBI" id="CHEBI:57836"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="49"/>
            <end position="53"/>
        </location>
        <ligand>
            <name>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate)</name>
            <dbReference type="ChEBI" id="CHEBI:57836"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR037091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR037091-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0020642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="914" mass="103213" checksum="94108EB984B6B120" modified="2023-09-13" version="1">MAMRGLTVFIADIRNCRVRELEEKRINKEMANIRTKFKEGSLSGYDKKKYVCKLLYMYILGWDIDFGHMEAVNLISSNKYSEKQIGYLGITLLMHENSDLVRLVVNSIRKDLDDNNEIHNCLALHAIANIGGREMAESLAGDVHRLLVSPNSKSFVKKKAALTMLRLFRKHPDVIPAPDWAERITNIIDDYDLGVCLSVTSLITALAQQYPEAFMMAIPKAITRLHKVIVERDFSADYVYYKIPIPWLQVKLLRLLQYFPPTEDPNMAEMLHNVLQTIINNSQETPRNVQHNNAQNAILFEAINLAIHMDCESDIVRQATNILARFILSKETNVRYLGLETMAHLAAVTDELDEIKKHEETIILSLRDKDISVRRRGLDLLYSMCDVSNAKTIVSELIRYLHIADYALREEMVLKIAIMTEKYATEHSWYVDVILQLISSAGDHVGEEVWYRVVQIVTNHENLQEYAAKMVLHYMRSPHCHENMLKVGGYILGEYGHLIANLPGASPIEQFNTLHARFGLCSLATRALLLSTYIKFINLFPEIKGAILAVFNQYRHVLDAELQQRACEYMAIATMPTDDLLQTVCEEMPQFPERESALLSRLNEKTNMTEDKRTWNIGGKDSNEKTPANLLAAKEKNENGNVDDLAAALGNAGINTPSAADEATPKAGLSWKDQLAPGYEVWYNRLRDGTDGVLYEDSILQIGIKSEYHGHLGRLAMYFGNKTHTQLNSFSVTVESPEGLVIASSHTLATSIGPSTQIQQLYSLECQQILTDVPLIRISYQAGSIQSIYLKLPVTLTRFIEPIQLASADFFGRWKQIGGPPREVQAIFKSSERINLEKARSVLVNNRMGICDNVDPKPGNFVATGVLNTSLSGKVGCLLRLEPNRETDMYRLTIRTTSDVVSKHLKEILQSALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1N6</accession>
    <name>A0A9P6N1N6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Minor extracellular protease vpr</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BGZ80_002147</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 9 10">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000152">
        <property type="protein sequence ID" value="KAG0021572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1N6"/>
    <dbReference type="OrthoDB" id="206201at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07489">
        <property type="entry name" value="Peptidases_S8_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1710">
        <property type="entry name" value="Subtilisin-like superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010435">
        <property type="entry name" value="C5a/SBT2-like_Fn3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046450">
        <property type="entry name" value="PA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034187">
        <property type="entry name" value="Peptidases_S8_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF66">
        <property type="entry name" value="SERIN ENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06280">
        <property type="entry name" value="fn3_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52025">
        <property type="entry name" value="PA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0134">Cell wall</keyword>
    <keyword evidence="6 9 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 9 10" id="KW-0645">Protease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="7 9 10" id="KW-0720">Serine protease</keyword>
    <keyword evidence="5 11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040276818" description="Minor extracellular protease vpr" evidence="11">
        <location>
            <begin position="19"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="12">
        <location>
            <begin position="139"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="domain" description="PA" evidence="13">
        <location>
            <begin position="355"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="domain" description="C5a peptidase/Subtilisin-like protease SBT2-like Fn3-like" evidence="14">
        <location>
            <begin position="596"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8 9">
        <location>
            <position position="148"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8 9">
        <location>
            <position position="198"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8 9">
        <location>
            <position position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR615500-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF06280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0021572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="17">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="861" mass="91352" checksum="4DB9EA640014ED65" modified="2023-09-13" version="1">MKITSIISLIAAATLVSAGKFQAADLRPNADVIPGAFIIEYHDGIDHAKANSILNSKKELSFKVRGKYNLFNGASIQVESGHSGEYLAKIPGIKRVWPVEVYQLPKAKPSNEDLTLPQLTSAHNMTGVDYVQKTFKYTGKGIKVGIIDSGIDYTHPALGGCFGKGCRVRYGWDFVGDDYDKTKVAKQDSDPRDTCNGHGTHVAGIIGADARKVGAPQPFVGVAPGVTFGAYRIFSCAGTGATDIIMLGMELAFNQGMNIINMSLGAGSAYKSNPIAVLADSLAARGLTVVTSAGNDGADGVWSVGNTGLGELSTAVASYDNVAGSYHYFKYAGAEHPYSFSQAWGKALNLPTNATLVPVFEKDGTLSDGCDADSYAGKNVTGKVVLVIGDVTRCKSGGRGAAAKAAGAAGMLIQTLPLGLSNLGGNLDFQMASIEFSAGQELIAGYKKNPASTFTWSSTKKSFRVEGGGRPSDFSSWGLDGELRIKPNIAAPGGNILSTYPLNMGGYAIESGTSMASPYVAGSHALLYSAHKKVLRGQDARQILMNTATPGSFFNHTEYAPVAKQGAGLINVRNAIATQTIFSPDRIELLDSVHFTGKNVEVKIKNVGKHTTVYTLSHETTESAISYRGGNSYPLATPILEADKATVTFSQKKVTVRAGQSVKVKVQFKEPATGKAIEFPFYSGYIVATPQGKASVPVRIPYAGVKGDIAKVPILDTDYGVPVLFVSNKKTGKVGAIEKGHKIDWAVEQPILVTRLGSHTPELSFRLFEAKSGKEVGYLNTQYGPVAASFGRSKNIDTNTNKPAIRTFNWLQGTVYTGINATVPTAVPAGEYKVIVAAQRKLSRGKFPADFEVYEVADVTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N202</accession>
    <name>A0A9P6N202_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GST N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_003374</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000189">
        <property type="protein sequence ID" value="KAG0020903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N202"/>
    <dbReference type="OrthoDB" id="4951845at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050983">
        <property type="entry name" value="GST_Omega/HSP26"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054416">
        <property type="entry name" value="GST_UstS-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43968">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43968:SF6">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE OMEGA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22041">
        <property type="entry name" value="GST_C_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13417">
        <property type="entry name" value="GST_N_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="2">
        <location>
            <begin position="11"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="283"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="288"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="317"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="338"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0020903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="362" mass="40284" checksum="4569E1A0CE93F15A" modified="2023-09-13" version="1">MAASLKLFELVDGKTRTISFSPAVWRARFALNYKKIPHEVVSLTFLEIPTVIPAACPNIDAPTAPTLQLETGQGLLDSLAIAEYLEEKYPDRPLLFGSPAEKKLQLFFQSYIQARIHPAIQRLVFEGMYNMQDDENAHYFRTSREKSAGQPYQEIPGDRNENIKELRENLGLIHNVLKSGDWIMGDHPGWADFVLGSSFMWFSSCSPNDFKEGVLEAFDDQVFPNFWNKIQHANDNALPSFDKSQENKQKKSGILKSLFGAMLNKKDATPTLVETPNYTGFGNSIGGSRPSTPASSAPYSSFNPDKGQLRPDFPISRPSSSNSNYGHGYQSHQNTDFGGQQQSYASSSAVYSHSTSSVGSRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2J2</accession>
    <name>A0A9P6N2J2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_002806</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000171">
        <property type="protein sequence ID" value="KAG0021238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N2J2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0021238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="188" mass="21554" checksum="CF010FECB0435AA8" modified="2023-09-13" version="1">METHPGDCLLALPSAGSELTGSRSYMEKAIKDINSDGKRAWTKETSKWLEAQHVARERDLPAPSPEARLGSEPAFSKVKEHIKTSTSITRYMVGRFVGAIDELGRTEIWNRRCELTVEWERENDIFPMRKRAKGHTCVGGLRRSRSDFIARSSHRPRLATDARDTRKEADERLVQSYLRQLDLNVMER</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2L1</accession>
    <name>A0A9P6N2L1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_002323</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000157">
        <property type="protein sequence ID" value="KAG0021468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N2L1"/>
    <dbReference type="OrthoDB" id="2440757at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0021468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="210" mass="23749" checksum="36BAF4D7B2BA6547" modified="2023-09-13" version="1">MDQFSLLKLLDSGQFVIHQLTESTQIALYQIGKVKDPERPGNDHNSDDSNDTNLDVNALTTKDGVKTVGINEENEEDDSEGQDEDLWDKDMKTHDWGATGHLFEDFEETEDKDDETDLKVSNSGETESWDSIQNNDDDDSGELRNSFAIGVQEENDYLQQEELDDESSENIDYYGCDFSKRLEKCSISEDMPSASEGCRGVYHIVVTLIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N358</accession>
    <name>A0A9P6N358_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Alkaline ceramidase 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ACER3_3</name>
        <name evidence="10" type="ORF">BGZ80_009202</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the alkaline ceramidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000053">
        <property type="protein sequence ID" value="KAG0023520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N358"/>
    <dbReference type="OrthoDB" id="187171at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046514">
        <property type="term" value="P:ceramide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008901">
        <property type="entry name" value="ACER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46187">
        <property type="entry name" value="ALKALINE CERAMIDASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46187:SF3">
        <property type="entry name" value="ALKALINE CERAMIDASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05875">
        <property type="entry name" value="Ceramidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="41"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="102"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="156"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="192"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="229"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="227"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR608901-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR608901-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0023520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="277" mass="31524" checksum="8BA3132A30ADC25D" modified="2023-09-13" version="1">MITSSPEYGTYVNGTWANSIQPVGYWGEPTSSDWCENNYDISYYIAEFFNSLSSFSMIIVGLVGMYLHSTFEKRFLLTFGSIVIIGLGSIAFHGTLLFPLQMLDEVPMVYSILSLAYCCIENRSYRRYGTWFPVGIALYGLITTLVMLFAGPDNHLLEFVVFQSSFAFVVLVVLSHLIKIYSETEDGPVKQIFMATFCTALISYLFWNIDFRMCNVMQSLPLNPQLHAVWHVGASVSSYLVTLLVCYNRAENLGRKPSIKWQWEMLPYVVVQHNKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N361</accession>
    <name>A0A9P6N361_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Microtubule-associated protein, microtubule dynamics during spindle orientation</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">STU2</name>
        <name evidence="6" type="ORF">BGZ80_001201</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000127">
        <property type="protein sequence ID" value="KAG0022034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005881">
        <property type="term" value="C:cytoplasmic microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990498">
        <property type="term" value="C:mitotic spindle microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044732">
        <property type="term" value="C:mitotic spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0099070">
        <property type="term" value="C:static microtubule bundle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061863">
        <property type="term" value="F:microtubule plus end polymerase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051010">
        <property type="term" value="F:microtubule plus-end binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051315">
        <property type="term" value="P:attachment of mitotic spindle microtubules to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030951">
        <property type="term" value="P:establishment or maintenance of microtubule cytoskeleton polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990571">
        <property type="term" value="P:meiotic centromere clustering"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046785">
        <property type="term" value="P:microtubule polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000022">
        <property type="term" value="P:mitotic spindle elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000019">
        <property type="entry name" value="Cytoskeleton-associated protein 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000068">
        <property type="entry name" value="cytoskeleton-associated protein 5 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000063">
        <property type="entry name" value="Putative cytoskeleton-associated protein 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034085">
        <property type="entry name" value="TOG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045110">
        <property type="entry name" value="XMAP215"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048491">
        <property type="entry name" value="XMAP215_CLASP_TOG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12609">
        <property type="entry name" value="MICROTUBULE ASSOCIATED PROTEIN XMAP215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21040">
        <property type="entry name" value="CEP104-like_TOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21041">
        <property type="entry name" value="XMAP215_CLASP_TOG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01349">
        <property type="entry name" value="TOG"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TOG" evidence="5">
        <location>
            <begin position="3"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="TOG" evidence="5">
        <location>
            <begin position="275"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="domain" description="TOG" evidence="5">
        <location>
            <begin position="595"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="domain" description="TOG" evidence="5">
        <location>
            <begin position="844"/>
            <end position="1077"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="508"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1070"/>
            <end position="1170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1627"/>
            <end position="1740"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1850"/>
            <end position="1869"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1881"/>
            <end position="1904"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1922"/>
            <end position="2001"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="538"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1103"/>
            <end position="1117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1130"/>
            <end position="1140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1629"/>
            <end position="1665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1672"/>
            <end position="1707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1731"/>
            <end position="1740"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1850"/>
            <end position="1866"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1922"/>
            <end position="1934"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1939"/>
            <end position="1972"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1980"/>
            <end position="1997"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0022034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="2061" mass="222280" checksum="C113B51647BD24E3" modified="2023-09-13" version="1">MDEFGGSAPEENFNSIPVQERLEHKNWKARVSAYEELAKLFRTSVEDSDFRRFEGSLKKIALDSNAVAQESGLTTLIQFVENAPDPNRTKNVVVPAVVEKCLSSTRTGTKAKALELILLYVEVDTPDPVIEDVLPGLDAKLPKLVATTTNALAAIVRTFGVKNINVKPLVKKLPPLFGHSDKNVRAEANALTIELYRWLRKAIMPSLEDLKPVQLKELTEAFEKIPDERPTPLKYLRSQQAEMAAAAAAAAAGGDDDGDGGQDEDQEMEMVDELDLIDPIDVSAKMESNFYELLASKKWQERKEALDGLLVHCKAPKILDSNYSELVGALGKRMADTNINIVIVAANCLEGLAKGLREGFNKYKGSVAGLIMDRLKERKATVTEALSGALNAIYNTLPYSELLEDTAANVVHKNPLIRAEVIKLQTHRLKEIKIVPSKQEIKTACEMLVKAFDDGDATVREATAEALGTLMKCCGEKPLMAYMEGLDTVKMGKVKEYCEKAVVKAKAAPVAAPKAPPPKAAPAAKPAPKKPAPKEEAAAPAKKPAAKPAAKPAAPSAAKKPVAKAAPAASSASSAAKKAAPAGGSKKEEEPLRYKFTNEGAEEQAAEFLTPELIAEFGDSSWKVRLEAMEKLHELVDSSTDFEAELITRVLAKKPGWKESNFQVTLKLYGILQLQAQKLPTFSKACAALTIPAMIDKMGDIKLKKAAGDCLATYAETLSLQFVLSQSYDPLKKLKAPKALADSLIWVNQQLEDFGITGLQVREMIDFLKVALGSANAAVRTNAVTVLGTLRRFIGPGIRSFVEDCNTALLAAIDAEFAKVADMEPPQVTKGASDDVGGAAAVEELFPKVDIGNQFTSSLLEECGDANWKVRKEGLEKVAAIVDANKRIKPNLGGLPGALKLRLADSNKNLQILTMEICAKLANAMGKPFEKYARILCSGVASCLTDQKDNVRSASIAALEAFATQGGLDSLISSLAVSLVTNSPTLRKDLLTWLTAFCNGLKERDAALPDLSPLAPPVIQCLQDRSADVRKAGQAFLPILMVNVGYDAVVAKCSDLKGAAKSAIMPMLEAAKPAPPPRPPSAAGNAKAPPPERGALNTLPSLPRSAAKAGARPGASALPGAPSKIAARPTASTLERTQTPPLREQQPSPTPVNPPFSSLPGPSQGSGIAAPRSRLTLKKPGEPVMDSGSLGVQPQVSRLHDMQPKYDEYQVPPVSNIQTPMNMGMQQRHFDPMDGVTATTQPLNGSRSIGSSNMGGMGGGLAMNNMSNMNGGIGGGLAMNNMNNINNMNGGMSQTQSAMVVPLKRLSVSGGELKGGENLMDYLVTQITSQDAYQSIDALKQLEKALHGPLDNIIPHVNELVNAHTLQIRLAYTGLEQRNNSTTRVCKHLVNSLVSIFSNKQLAIKVRSDPLYNLLHELASRLLDKNLDKVESGQQLAKALNVTMVKVLENSNRNATFNALLLILVRCAQPLRNVEDSAHQAKFGDLIMKCIWKLTKTIKECVAAGTLKPDELLADMNDFLVSISPPEWKRRAQEGVPLGDMPLRTVKTVLVELSSGMGDEVFNHLGLIQDPTKSAIHQYLVHMTGSKKRPIAQVQNPAMQPLPNNTGRDRMPVVGAMTNQNLGVHNMMQQQQQQQPQQQQQQQQQQQQQHIPPSPQFQHSPQFQQRPISPRTPMQSTFGSQLQTPQVSNFGPSQNEFSGAGVSQNRMSMAMGQMQAPSPDPGANEIKSAGDPSSVSETEMNSRLTQIFTKIGTREETKQGIADLYQFQKMYPNMESKVNAQLSKTGTFFQSYIRRGLANLEAEANAVAMGGSTPTPTSGLGMSGIGMSGIGSPAINRDVADIIARKRESVLSVSNSDSSSMSTDPSESYKDRLARLQQMFGYKSESKTPSPVQDGHDANARLMEGRNSPNLSLRQQQELDFQQHQLQQQQILAQHNRSRPSSLYQTTLSGPTASPTASQFGSSISGMHSPYQTHFGHQEGGNINSGINNNTNGGLTSVTPTPSLQALQESMAAKERAQTVALMKERLAKMKSQTLTSSQLALQQFHQQQTGGPDGGNGTHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N391</accession>
    <name>A0A9P6N391_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Dynamin-like GTPase that mediates homotypic ER fusion</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">SEY1_2</name>
        <name evidence="8" type="synonym">SEY1</name>
        <name evidence="12" type="ORF">BGZ80_008914</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Endoplasmic reticulum membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <text evidence="8">Enriched in the cortical ER. Concentrated in punctae along the ER tubules.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. RHD3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000050">
        <property type="protein sequence ID" value="KAG0023589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N391"/>
    <dbReference type="OrthoDB" id="1597724at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016320">
        <property type="term" value="P:endoplasmic reticulum membrane fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01851">
        <property type="entry name" value="GBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000727">
        <property type="entry name" value="Protein SEY1 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03109">
        <property type="entry name" value="Sey1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030386">
        <property type="entry name" value="G_GB1_RHD3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008803">
        <property type="entry name" value="RHD3/Sey1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046758">
        <property type="entry name" value="Sey1/RHD3-like_3HB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45923">
        <property type="entry name" value="PROTEIN SEY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45923:SF2">
        <property type="entry name" value="PROTEIN SEY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05879">
        <property type="entry name" value="RHD3_GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20428">
        <property type="entry name" value="Sey1_3HB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51715">
        <property type="entry name" value="G_GB1_RHD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 8 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="topological domain" description="Cytoplasmic" evidence="8">
        <location>
            <begin position="1"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="683"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="topological domain" description="Lumenal" evidence="8">
        <location>
            <begin position="704"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="707"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="topological domain" description="Cytoplasmic" evidence="8">
        <location>
            <begin position="728"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="domain" description="GB1/RHD3-type G" evidence="11">
        <location>
            <begin position="62"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="755"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="474"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="763"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="780"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="72"/>
            <end position="79"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0023589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="801" mass="91757" checksum="BE616C7A2F1B34F0" modified="2023-09-13" version="1">MDVVPDVDHLSAHDNPVPDVLDSANSNPKALQPRLHLIDEQQKFSETLSTYIARDWGLGDAGFNYNVAAVFGSQSTGKSTLLNRLFGTSFDVMSETARMQTTKGIWISKGRNMKVLIMDVEGTDGRERGEDQDFERKSALFSMATSEVLIVNLWEHQVGLYNGANMGLLKTVFEVNLQLFGGNRGKEKTLLLFVIRDHVGATPLANLSNTLRADLERIWHGLSKPEGLEDCKITDYFDFMFTTLPHKLLQPEKFETEVDNLRLRFSDPSDPNYVFQPQYSRRVPVDGLHIYAGGIWDKIMTNKDLDLPTQQELLAQYRCDEIANAAFATFQEKIKEFRQPIETGNIVENLGPKMNEIRGAAIKSFDKDASRYHAEVYKRKRADMLNKANHMLEAYFLGQLKNLHKKAVNMFSTNLQQALRADGAEFSVAVAAAKKEALDYFLQGAKAIKLGETEWSYDEEQYQLEQGLQEFATAQREKELNKMLTNLEKNLRNELDEPVGLALNNPGPGMWGRVITIYQRTVEEAEQLLQKKARTFDLNEKEQAELTVNLRRQAWVLLTKKVQEESVDGMMLLKLRNRFEEKFRYDDHGLPRVWKPDDDIDTPFRKARDETVELVPLFAKINTMDPVKGEKFELEPSDDFDFDQSLKVLSESRQQEITTKFKRESDAFYLEAKRSVVSTQAKIPYWVGIALIILGWNEFIAVIKNPLYLMVTAMVGVPMAVMWYLEMLGLVETIARSVFDQGYKIAMDKLRENMDKGREDRPPQYQRQPQQYPSLSNKPSRTDSYKEESGIELSSMEKKSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3F0</accession>
    <name>A0A9P6N3F0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_009526</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000058">
        <property type="protein sequence ID" value="KAG0023402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3F0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051222">
        <property type="entry name" value="PPR/CCM1_RNA-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47942:SF63">
        <property type="entry name" value="PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47942">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT (TPR)-LIKE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="126"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="211"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="278"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="401"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="13"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="99"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="171"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="279"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="293"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="317"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="328"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="341"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="356"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="411"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0023402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="457" mass="49841" checksum="5030EFAF92735A1D" modified="2023-09-13" version="1">MNWIGSVPSITESSTTDASPTMSASSSSILSSSSRAPNALTVSPADRVWGIWHDFLLTGMSPDVVLYTAVIGVLLKANEYDRVNQVWQHMHRRLDHQNQDQGRNSGCQSRKKDTVEEIDVVSKTLSHGTSTSLLSPSPSPSPLLSTVCNVDERPKGRRKSNAIDLLDSENQRPQNRKSVTPNIQTYSVLMQTHVLKRDIQGVAQTYKEFLQSTAPPPPSTSASRSTNVASASEKHQQQHGTRANTVFLNQILTALVNLGENNAAKEIYAAMRLDHDQAHSTSATANNADNAEEEKKEEEKTLAKRVELSKSRDEVGSTVNDDYTSKATLLPTSSTSSSLPLPLPLPLPSPSPSPSVPGTISSFLTGSTLASSSNSSPVHHRNSERRSTWLKRVVHEARKSQLSVFKGKGKSPSSSTLLSSIQPDNTTRKLILKMARRKNDTALEEIVLKDLDSDFVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3J4</accession>
    <name>A0A9P6N3J4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Aspartate--tRNA ligase, cytoplasmic</fullName>
            <ecNumber evidence="3">6.1.1.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Aspartyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">DPS1</name>
        <name evidence="15" type="ORF">BGZ80_007430</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>tRNA(Asp) + L-aspartate + ATP = L-aspartyl-tRNA(Asp) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:19649"/>
            <dbReference type="Rhea" id="RHEA-COMP:9660"/>
            <dbReference type="Rhea" id="RHEA-COMP:9678"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78516"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.12" evidence="3"/>
    <dbReference type="EMBL" id="JAAAID010000038">
        <property type="protein sequence ID" value="KAG0023899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3J4"/>
    <dbReference type="OrthoDB" id="372395at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017101">
        <property type="term" value="C:aminoacyl-tRNA synthetase multienzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004815">
        <property type="term" value="F:aspartate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006422">
        <property type="term" value="P:aspartyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04320">
        <property type="entry name" value="AspRS_cyto_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00776">
        <property type="entry name" value="AsxRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000013">
        <property type="entry name" value="Aspartate--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000132">
        <property type="entry name" value="Aspartyl-tRNA synthetase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02075">
        <property type="entry name" value="Asp_tRNA_synth_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004523">
        <property type="entry name" value="Asp-tRNA_synthase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00458">
        <property type="entry name" value="aspS_nondisc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003483">
        <property type="entry name" value="PRK05159.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43450:SF1">
        <property type="entry name" value="ASPARTATE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43450">
        <property type="entry name" value="ASPARTYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 15" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="14">
        <location>
            <begin position="241"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="27"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00033155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0023899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="546" mass="62316" checksum="E835E84048F28FD2" modified="2023-09-13" version="1">MATNTAIDEVTQQVQEVILDENGQPLSKNALKKLEKEKLKKERAEAAAAARAAQASAQASAAVDYSKDFYGKKPMNQSDSRPGLKHERLSDINASRAGEKVWIRARVQTSRPTGNKMCFFQLRQNSSTIQGLVVFNDSTISKQMVKFAQNITSESIVLIEGTIAKPLEPVKSCTVQDAEIMISQVFVTSEAQGRLPFNLEDASRPETDFEREDAQFSKVTLHTRLENRVFDLRTITNQAIFRIQAGVCRLFREFLESKGFLEIHTPKILGAASEGGANVFKVKYFDTDAYLAQSPQFYKQMVVCGDFERVFEIGSVFRAENSFTHRHMTEFIGLDMEMAFEEHYHEILDVFDELFVHIFTGLETQHASDLEIVHRQYPFEKFQFLPKTLRLEYKDAVALLRENGIEMGDYDDLSTEVERKLGQLVKEKYHTDFFMLDKFPLEVRPFYTMPDPNNPKYSNSYDFFMRGEEILSGAQRIHDPDFLIERAKVHGVDPESIKSYVDAFRMGAPPHGGGGIGLERVIFFYLNLGNIRRVSLFPRDPKRITP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3K4</accession>
    <name>A0A9P6N3K4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">CAAX prenyl protease</fullName>
            <ecNumber evidence="15">3.4.24.84</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BGZ80_000041</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Proteolytically removes the C-terminal three residues of farnesylated proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 15">
            <text>Hydrolyzes the peptide bond -P2-(S-farnesyl or geranylgeranyl)C-P1'-P2'-P3'-COOH where P1' and P2' are amino acids with aliphatic side chains and P3' is any C-terminal residue.</text>
            <dbReference type="EC" id="3.4.24.84"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14 15">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="14 15">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 15">Endoplasmic reticulum membrane</location>
            <topology evidence="1 15">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12 15">Belongs to the peptidase M48A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.84" evidence="15"/>
    <dbReference type="EMBL" id="JAAAID010000100">
        <property type="protein sequence ID" value="KAG0022537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3K4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07343">
        <property type="entry name" value="M48A_Zmpste24p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2010.10:FF:000002">
        <property type="entry name" value="CAAX prenyl protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2010.10">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027057">
        <property type="entry name" value="CAXX_Prtase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032456">
        <property type="entry name" value="Peptidase_M48_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10120">
        <property type="entry name" value="CAAX PRENYL PROTEASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16491">
        <property type="entry name" value="Peptidase_M48_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 15" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 14 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 15" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2 15" id="KW-0645">Protease</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7 14 15" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="123"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="166"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="195"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="308"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="338"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="domain" description="CAAX prenyl protease 1 N-terminal" evidence="17">
        <location>
            <begin position="50"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M48" evidence="16">
        <location>
            <begin position="228"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="active site" evidence="13">
        <location>
            <position position="298"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="13">
        <location>
            <position position="380"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="297"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="301"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="376"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00060927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR627057-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR627057-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU366005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF16491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAG0022537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="443" mass="51482" checksum="4A562AFFE0A32258" modified="2023-09-13" version="1">MGTSLYDTLYRSAGIFLGREKTDSFPYKEWVLGFMYIVFLWEEYLRFRHYRNLRSNVRPKALSEHVTEEQFLKAQAYGQDKTRFGFVKSIFDQTENTLTIALGFMPWLWNLSGDIMFKITQSVIFFMAMSIFSTIISLPFSLYSTFVIEERHGFNKQTLKLYFSDLIKGHLVGGAIGMPFLAGFLKIIHISGKNFYFYVWLFMVAFQLIMVSIYPTLIQPLFNKFEPLPEGELRTRIEALASRIQFPLTKLFVIDGSKRSGHSNAYFYGFFKNKRIVLYDTLLEHSDNDEICAVLAHELGHWACNHTLKMLIFGQVQLFVIFYLFSQFVNDKAMYTSFGFMDATPTLIGFLLFNYLYSPVESVIGFITNMISRRHEFQADAFARDLGYSASLISGLIKLQLKNLGTMNPDWLHSMYYRSHPELIERLDAINRHSVGSKVEKVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N486</accession>
    <name>A0A9P6N486_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_009530</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000058">
        <property type="protein sequence ID" value="KAG0023406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.80">
        <property type="entry name" value="E3 ubiquitin-protein ligase SopA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056251">
        <property type="entry name" value="Arm_rpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055496">
        <property type="entry name" value="DUF7068"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848:SF8">
        <property type="entry name" value="F-BOX AND WD REPEAT DOMAIN CONTAINING 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23948">
        <property type="entry name" value="ARM_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25173">
        <property type="entry name" value="Beta-prop_WDR3_1st"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23238">
        <property type="entry name" value="DUF7068"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05729">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141571">
        <property type="entry name" value="Pentapeptide repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50837">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="13"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="741"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="783"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="825"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="867"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="909"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="951"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="993"/>
            <end position="1034"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1035"/>
            <end position="1076"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1077"/>
            <end position="1118"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1119"/>
            <end position="1160"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1161"/>
            <end position="1202"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1203"/>
            <end position="1244"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1245"/>
            <end position="1286"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1287"/>
            <end position="1322"/>
        </location>
    </feature>
    <feature type="domain" description="NACHT" evidence="5">
        <location>
            <begin position="1558"/>
            <end position="1685"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="534"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1436"/>
            <end position="1455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="534"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="2005"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0023406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="2005" mass="226708" checksum="B15D7051A48B0C55" modified="2023-09-13" version="1" fragment="single">LRGLDRLVQEGRFADFEQLVREAPCRHNPAFRWGVYQRLGEIAANIVWDLNTRKCAVNFLRQEYDNDVNKDQQVNTLQWILYILNQLAESYKDIIDGPVQELLLEAQTSSSSGKETPYRGYDNLTLHPIVVTPPLTEFPLLDFVQNKPDVEAPLRQLRRERLKDRGGDVYISPRAKATSRATDHFDLNTKVQEFLASDRKVFLLLGDSGAGKSTFNRALEINLWDNYDKTNGRIPLFIYLPAIEKPERELIAERLRQANFTESQILELKLYREFILICDGYDETQQTRNLYMSNQFNQPGQWRAQMVISCRVEYTGVDYKDCFQPIDRNSGKDTGQYQEAIISPFTKEQVQDYIEQYVSLRKSSWGLEDYLKALKRIPNLQDLVKNPFLLKLSLEVLPHLSRFSSTHITRVQLYDEFVAQWIDRGKIRLREMELSPYDKETFKRMTDSGFQQHGITYLKELVTAIYEHQNGNPVVYYSEHHDRRTWKEAFFSEKDGRHLLREVIPLTRNGDQYRFIHKSLLEYGLTLAIYEPSKRNEETEEKPSMSRRGSTSSVLSFECVPSTERKTTADEQSLLDSPLGKRNLVGEPYVLRFLTERVREEPVFRDQLNAVIERSKYDKTVRIAAANAITILIRAGFRFNSADLRNIKIPGADLSFGMFDSAQLEGADLRKVNLRNVWMRQANLRGAQMKGAQFGELPFLQEDDRVMCCAYSPDGKTYAAGLYNGNISLYKTSSWDRTQTLKGHGGCVNSISFSATGDRVVSGSLDSTVRLWDVHTGKCVYVLQGHSGQVMTVACSPKGDRIASGSRDNTVRLWDIDTGKCVHTLQGHSSWVFSLIYSSNGDRFASSSDDRTVRLWDADTGKCIYVLKDHNAIVRTVTYSPKVDQIASGSDDKAIRLWDVNTGKCAHTLEGHSGWVRSLSYSPIGDRVASGSDDKTVQLWNAQTGERIHTLKGHGDVIPTVMYSPKGDRIASGSYDKTVRLWDVDTGECIQTLQGHSNYVVIVMYSPKGDHIASGSYDKTVRLWDVDTGECISTFQGHSGWVRSVMYSPKGDQIASGADDSTVRLWDVETGECTHTLQGHSRGVGTVVYSPEGDRIATGSDDSILRLWDVDAGEFIHTLRGHDRDIKIVAYSPKGDQVATGSYDNTVRLWDVNTGECIRTLQGHSWAVRGVAYSPKGDQIASGSYDKTIRLWDVETGECVNAFQGHDHWVRCVVYSPKGGRLASGSDDSRVRLWDLDTGECIHTLQGHSRFVSSVAYSPKGDYVASGGDDRTVRLWDVETGQCLTIISGFSNCVGSIAFENNFSSLYLVTGSWDKSIRRWRIIKERDRHKAALCWSSSHEVLTICDLSFEDVQDLSGSNQRLLIQRGALVPKSMSSGQDSLVGFERDDMPNEHETEQTKLILFRTLLTLGEKAQEGQYHTQDDLYQGQVEIKEASNYHEQSTGDHPIDAQERPEDSSPALLSFNHVQLALQAYYEPYLNIQRASGDTLNLESCYINLTIVEASDQRQKDKEGLKVRAAGLYRVASYGGITKTNTKAPIPLEKLFDKRLLRDGGEDVPKATLIQGRAGSGKTTLCKKLVNLHQSGLWRDRFDAVLWLPLNQLKGLGARNIEDLLHEKYFAQHLEQERETPVSLTAAHARSGKILFLLDGLDEIILDAKSGNDAALGPLLKYLLRQNHVIITSKPSGVDTSILPTLDLELETIGFSMENVNDYLHRVLNPDTAKVVQGFIKATPLIQDLVSIPVHLDVICFNWDALLLDKDSLTITELYQPMVTKLWCRYLLKKSTAGEELEPRQIKSLSQHQIDQLVAAENEYLGYLAFKGFRDNQIKFHERSLCGAIEELNQHRVKANQELLPPQLPDMLKQTSFLHTADADSDAGMDCSQHAWYFSHLTFQEYFMATWLARHLQIEQNGSISSPTPMMTVEETKAYIRQHKYNPRHHIVWWMLAGLLEGEALTSFFGVLQEAPEDSTGGYHFHLLAACLKEGRSQLDSESAKGLEVQLAQWLHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4W6</accession>
    <name>A0A9P6N4W6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peroxisomal membrane protein PEX16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PEX16</name>
        <name evidence="3" type="ORF">BGZ80_008691</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Peroxisome membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the peroxin-16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000048">
        <property type="protein sequence ID" value="KAG0023653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N4W6"/>
    <dbReference type="OrthoDB" id="2021143at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007031">
        <property type="term" value="P:peroxisome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013919">
        <property type="entry name" value="Pex16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13299">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13299:SF0">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08610">
        <property type="entry name" value="Pex16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="2" id="KW-0962">Peroxisome biogenesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU365003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0023653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="365" mass="41449" checksum="E7D82070C5AA9457" modified="2023-09-13" version="1">MDFLKKYESFIFKNATQISSIESTLRSLTYILPGRFDDADLASEALFSTLNLLGIYHDTILTKHVASLPATHRPTPSALNRYTRDWQNSSVAYRRIVLLLTVIQYTEVLIEMSVQKKWGQQYKWRVITALETIKAVGRLGLMRLTNGRMLMHPVHTERDVDPAKLADLAEAELSVKESHWTGTRTGSQRLQLSAVQKSTGKSGKNSDVTDFLLSKVLTPDVVRKPRDLVSRLTGLGAIGECLFILRPIIYVLAMRKYGQRSWYPWFLSLAIELVSRTSIKHCLAARAAGGRGASGTPLEKDEMKRRLWLLLYYVLRSPFYDQFTKERLNNFCESASKKPLISLVGGIVQDYQPLWESVYFYTAGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N616</accession>
    <name>A0A9P6N616_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_002768</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000017">
        <property type="protein sequence ID" value="KAG0024454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N616"/>
    <dbReference type="OrthoDB" id="433738at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039663">
        <property type="entry name" value="AIP/AIPL1/TTC9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11242">
        <property type="entry name" value="ARYL HYDROCARBON RECEPTOR INTERACTING PROTEIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11242:SF0">
        <property type="entry name" value="TPR_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="66"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="146"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="175"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="193"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0024454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="202" mass="21857" checksum="6FE506C61C157667" modified="2023-09-13" version="1">MALTCSDIFKFIFAVILPPLGVLMEAVIGLNGLDNQMSGVPMMSSMQPKNSEASEHQKNEIKTNLAIIYSNMAACHLKNGKYARAIEVCNSALKNDPDNVKAKFRRGQAKAADGNLAGAEADFLSLGEQVPGVKAELMKLKSKFKEADEKQRKTMGGFLSRGRIITDEDDEEAGTTTSKSTPASKSSSTPTPKIRELEEGEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SRM0</accession>
    <name>A0A9P6SRM0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DDE-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_007798</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004057">
        <property type="protein sequence ID" value="KAF9994476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SRM0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004875">
        <property type="entry name" value="DDE_SF_endonuclease_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03184">
        <property type="entry name" value="DDE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE-1" evidence="2">
        <location>
            <begin position="2"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="204"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9994476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="237" mass="26797" checksum="48FA858C8CE5C3A4" modified="2023-09-13" version="1">MELKYVEVFPFPPNTTSVFQPIDARVIAAFKRRYWRIHWEHALISDIENKASLLSGKQQDNAFVSYDKIFKINQLEAMAFVKAAWDEIMATTIFNCFQYTGIFKTPPPQESSDAPTSEATEGMLDLSGDNNSEEDEISAGKDIVYCDLGGDLGALDASVSDKVEEESYLRLPAPDTLQYDEALLNKNPYHQSMTTEELLKAVVDKDVDEDEGADNGNEDDKEEYEKLLQDRRCSRVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SSQ9</accession>
    <name>A0A9P6SSQ9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007175</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003628">
        <property type="protein sequence ID" value="KAF9996743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SSQ9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9996743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="112" mass="11983" checksum="32E94250E3C55A87" modified="2023-09-13" version="1" fragment="single">MAKGDIQTPPGTGHVESLTPDQKELLKQMWAEIFRIQDSGSLDLPADLLAPPNDTASVKSKGTVKKGWFGSSKSVPPAEEPAQTTRVNLADIGLDVATLRPALWNNVLGDHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6STI8</accession>
    <name>A0A9P6STI8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_006246</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003078">
        <property type="protein sequence ID" value="KAG0001032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6STI8"/>
    <dbReference type="OrthoDB" id="4364at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033573">
        <property type="term" value="C:high-affinity iron permease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015093">
        <property type="term" value="F:ferrous iron transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004923">
        <property type="entry name" value="FTR1/Fip1/EfeU"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31632">
        <property type="entry name" value="IRON TRANSPORTER FTH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31632:SF2">
        <property type="entry name" value="PLASMA MEMBRANE IRON PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03239">
        <property type="entry name" value="FTR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0410">Iron transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="42"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="74"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="106"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="182"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="221"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="226"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="238"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0001032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="251" mass="27464" checksum="69030D22A4D8DA64" modified="2023-09-13" version="1">MITVMGIAMLRSNQMQEKWKVKLAKAMNAENERGFGNQSRKYALFILPLITVLREGLEAVVFIGGVTFTEEPKAIPLAVLAGVALGWLVGFAIYRGGNRMRLHQFFVGSTCLLLMIAAGLVSKGIAAFEADRWNRLTGAQSDDAGTYDPRVNVWALKCCDPKQPDSEWWGVANSLVGWSNVASYWTVGSYILYWGLVSAWLIRMKSKKGKALTAERRPLLGATDANGSNGSTSGSRNAETHSSRQDEITVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SU46</accession>
    <name>A0A9P6SU46_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_006055</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002993">
        <property type="protein sequence ID" value="KAG0001923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SU46"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0001923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="373" mass="41887" checksum="049BF02949257915" modified="2023-09-13" version="1">MDFINGVYPSRVTTDGIFNGLPYYRTRTSSVDTHSPTLLFFNLEQSVSTSNSTADKVIELIHNQGNPLLPIFGCGKTRTAIEILSRHWGFYFNASGTDFGSGDLAQFINSTTDNRYRSSNQQSNNNIHILTLALLLARIMILDHTIKLVSNSNSKMTKRGFLPLDWMKMQVSPHSVLSVDLFKTLFTLIVNKIHNNQILKSEVEELIQTKFSDLQTLIHGLRRQKFINNRYKILIIIDEAQTLGNNDPGSIMSGFISEMDNTISQPLLSPFMHGIYMISANDQDYGVIPCGTGLSVFDMKWLADSASWVKGNADRPEPFTDFGGWASLGELTKYCNSLKNHLSLRMQKLPLIYALHKRLKGNCFEISMAGSAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SUI7</accession>
    <name>A0A9P6SUI7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 11">Cystathionine beta-synthase</fullName>
            <ecNumber evidence="4 11">4.2.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BGZ80_005618</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9 11">
            <text>L-homocysteine + L-serine = L,L-cystathionine + H2O</text>
            <dbReference type="Rhea" id="RHEA:10112"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:58161"/>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
            <dbReference type="EC" id="4.2.1.22"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-cysteine biosynthesis; L-cysteine from L-homocysteine and L-serine: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the cysteine synthase/cystathionine beta-synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.22" evidence="4 11"/>
    <dbReference type="EMBL" id="JAAAID010002769">
        <property type="protein sequence ID" value="KAG0004417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SUI7"/>
    <dbReference type="OrthoDB" id="728at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004122">
        <property type="term" value="F:cystathionine beta-synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019343">
        <property type="term" value="P:cysteine biosynthetic process via cystathionine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01561">
        <property type="entry name" value="CBS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04608">
        <property type="entry name" value="CBS_pair_CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000003">
        <property type="entry name" value="Cystathionine beta-synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000118">
        <property type="entry name" value="Related to CYS4-cystathionine beta-synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046353">
        <property type="entry name" value="CBS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050214">
        <property type="entry name" value="Cys_Synth/Cystath_Beta-Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005857">
        <property type="entry name" value="Cysta_beta_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001216">
        <property type="entry name" value="P-phosphate_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01137">
        <property type="entry name" value="cysta_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10314">
        <property type="entry name" value="CYSTATHIONINE BETA-SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00901">
        <property type="entry name" value="CYS_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 10 11" id="KW-0129">CBS domain</keyword>
    <keyword evidence="11" id="KW-0198">Cysteine biosynthesis</keyword>
    <keyword evidence="7 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 11" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="12">
        <location>
            <begin position="372"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00026192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0004417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="499" mass="54049" checksum="8FCE8C955A39AA08" modified="2023-09-13" version="1">MSPSTCEINGCNQIGSHRHEEHLPEPAILNTILDHIGNTPLVRINKIAKSEGLQCELLAKCEYFNAGGSVKDRIGKRMIEEAEKDGRLKPGCTIIEPTSGNTGIGLALAAAVKGYRTIITLPEKMSQEKVDVLKALGAEIIRTPTEAAWDSPESHIGVAKRLNAEIPDSVILDQYSNPYNPVTHFDHTAEEIYRACNGQIDMLVAGAGTGGTITGIARKLKALCPGIIVVGVDPHGSILAQPESLNTSTESYKVEGIGYDFIPEALDRTLIDRWIKSEDKESFIMARRMIREEGILCGGSSGTAVAAAVKAAKELGPGKRCVVLLPDSVRNYMTKFLNDQWMQTNGFTDQAMATEQESKHLQWGGATIGDLHLKAAVTVTNTSQCREAILLMERNGFDQLPVVSSKNGRLVGLVTLGNLLSRIAAGRVQVDGQVHDVMFKFQKTGTHFVEINDDTLLEDLTAFFEKNSAGVVTERGGSKVKAVVTKVDLVSYLVKKTAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SUI8</accession>
    <name>A0A9P6SUI8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005546</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002730">
        <property type="protein sequence ID" value="KAG0004862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SUI8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0004862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="580" mass="65898" checksum="CC94B561225D3EF9" modified="2023-09-13" version="1">MTLAKTLCISLEAGKMVLKKKARKSRKLSNPQTEQTNRSTSPALDKQISVHRFFHLVNYRSWNQIDVFHKYRDPSISAENHAIIYKSDLERISNNSDIPESLRKVAFNLVRNFKSDEFVTRFAELTDVIAERNANQGIRNIFLKVAGNLGTGDGDHRLRPEGNQPKKIKLDSTLESNVEETASAHALHAPEDDAVEVETARALEVDIEIEAVDLEDDDEETEAVDLEDDGEETEAIDLEDDDDEEEIDATASIEYDDEEIEATATPSNVLEKGTSKRVVAVSTLQQTLQDPYQDPAMKSRIKRFKQMDQTKFWKLSSGRTVEQILFEKSINGGASYKIRSYTIDYTCVITQKLFTNQEWTEIQTYNEWELPDLEETTFNYLESVCNTLQKGGHPTVVPFPADDWNTCNLVLRTALACNPSAHSEAFWARHGWPALKDLLNGVDGITMLDGEKYSLESTQHKNKNRRLDVEVKTNVEKKTIRKAAGMYNCSNAYISLFHEYPPHVLPTEAGDWVDQFIGLWFLLRVKIAATQTIQLYNQRPQRNLRDLANHVNIIGYDNEQSTMEDCTLASSPLGPDSFDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SVC7</accession>
    <name>A0A9P6SVC7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Translational elongation factor EF-1 alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">TEF3_2</name>
        <name evidence="13" type="ORF">BGZ80_005143</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein biosynthesis; polypeptide chain elongation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002553">
        <property type="protein sequence ID" value="KAG0006778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SVC7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03221">
        <property type="entry name" value="ABCF_EF-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000076">
        <property type="entry name" value="Elongation factor 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000193">
        <property type="entry name" value="Probable Elongation factor 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1390.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050611">
        <property type="entry name" value="ABCF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040533">
        <property type="entry name" value="EF3_4HB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047036">
        <property type="entry name" value="EF3_4HB_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211">
        <property type="entry name" value="ATP-BINDING TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211:SF5">
        <property type="entry name" value="ELONGATION FACTOR 3A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17947">
        <property type="entry name" value="4HB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24984">
        <property type="entry name" value="HEAT_EF3_GNC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24987">
        <property type="entry name" value="HEAT_EF3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 13" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="HEAT" evidence="11">
        <location>
            <begin position="161"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="426"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0006778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="629" mass="68388" checksum="F4460017C1DDAB8C" modified="2023-09-13" version="1" fragment="single">MSAPLIDAIVKAENTEQRQAAADALAAFAKSEGLVKSVAIIESLNPLLENKKSVPHREGALLALGSLATVFGQAAEPFLIPQMPKVFELYSDKMVPVRQAAEVASKAIMGLPTRYAVRLLLPVIFHAIKESKWQSKIGAMDILSGLTFTAPQQIAAALSDIVPVVSEAMWDSKPEVRTQATKTTTDCFNVVGNPDLTSSIPYLVGCINRPEEAAECIHQLAATTFVTTVEEPTLAIMCPLLVRGLAERTPSIQRQTAVIIDNMCKLVENPAHAQQFLPKLLPGLDRMIEIGASPELRGVAERARATLVRVGGGEPGSKDQVVTIAYSVSSTQVLEVLKTKATFVKEDSFSSAVLAYVSTLCAELIASRNFEKDAWVSSISPYLTTLGSDAEVAAFADEFNAYWVDYDAKNALSNAAVADVEEGELLCDCEFSLAYGGMILLNKTRLNLRRGQRYGLCGPNGVGKSTLMRAIAEGQLEGFPSPDELRTVFVEHNLQAEDADLPVLTFIFNDEKIKNLEKKAVVDMLESVGFDKEKQEQAVGSLSGGWKMKLELARAMLMNADILLLDEPTNHLDVANVAWLQNYLTSLTNVTSMIVSHDSGFLDAVCTGIIHYETRKLKKYKGNLSKFVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SW06</accession>
    <name>A0A9P6SW06_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Increased recombination centers protein 22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_004999</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002494">
        <property type="protein sequence ID" value="KAG0007155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SW06"/>
    <dbReference type="OrthoDB" id="5561232at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040451705" description="Increased recombination centers protein 22" evidence="2">
        <location>
            <begin position="20"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="222"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0007155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="287" mass="31632" checksum="ABB24EE02BE5F665" modified="2023-09-13" version="1">MKFFSLATALLALTAIVSAQDVEKRLIDVSDTELDVKEVHNKPDVDTFVVTVQRTDDLLADDGTFLAERVMAVAFDFDVQDHEVLINKVPLGLESQPEEPISVTMTVEAGVIVGPALDPETKVEDLMNAFDTGLVTVQVSASTEFVTTDDGSVVRRVTLQETIVEVNGHEIVQTDAAQQVLEIMADGSLGSYTPLPFGKSGCQTRFNEAVKSVEEWFHSLNWPAFLCAGVIAFAMFIVSATTLRSLVQKRRQARYAKIHQEEVSEEFIQVAIIDDKKLDDEKKALVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SW27</accession>
    <name>A0A9P6SW27_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CID domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_004373</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002233">
        <property type="protein sequence ID" value="KAG0007677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SW27"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048471">
        <property type="term" value="C:perinuclear region of cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006569">
        <property type="entry name" value="CID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12323:SF0">
        <property type="entry name" value="CALCIUM HOMEOSTASIS ENDOPLASMIC RETICULUM PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12323">
        <property type="entry name" value="SR-RELATED CTD ASSOCIATED FACTOR 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04818">
        <property type="entry name" value="CID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51391">
        <property type="entry name" value="CID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CID" evidence="2">
        <location>
            <begin position="39"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="422"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="189"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="259"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="280"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="422"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="443"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0007677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="529" mass="58907" checksum="E859CA4D803B4EDF" modified="2023-09-13" version="1" fragment="single">MDNLPYPARQNQPLPTPADLGPAGVQLALDALLQQSRGLTPADIATFMDHLELLMKDCSQANIQVGKNWVVQHCQTPQQYDLISRAMVAIAISRKSFNDKLHIVYLTNDILSHSERKQQRWIKEAFYPHLVPILRVAYYFPGIDDSQRQRVIKVLDIWRNKEFFPANIVDTMEANVRRPPLLPPPPPAGGLIHPIPTHIPAAAPHQQAPHQNQYPPQHPPQHLQHPPQAQQHVNPHPGSWPPPNPHMPGPHHPYPTYPPTQQQQFGQPVAPLPFQHPHHIIQPGFQQQPPQQQQQPQQQQQPHMQGVYHPPYQTQAAHPVVTPAPAAPPPAPTHRDTLTRDLPAGLMMSKIESNADYYEPLPAYVSIPIQKTDVLKGNILESVNEFILENSTIQPEGNSNGIKNEGWHEGYLDEFYKTVSEKRKREFSKDPKPSRHRRHGQRQGRGQGQGLGLGLGLGPDPYLDLGLGLVLVLGDGPDHLLVRGLDPDPEPGLEHVQGVDHHHIAAGTEAKVEAGVGVEVIVVVEVGAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWA2</accession>
    <name>A0A9P6SWA2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Nadh-ubiquinone oxidoreductase kDa subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_004559</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002310">
        <property type="protein sequence ID" value="KAG0007534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWA2"/>
    <dbReference type="OrthoDB" id="2093409at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22903">
        <property type="entry name" value="NI9M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039961">
        <property type="entry name" value="Nuo9.5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38488">
        <property type="entry name" value="OXIDOREDUCTASE 9.5 KDA SUBUNIT, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G08980)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38488:SF1">
        <property type="entry name" value="OXIDOREDUCTASE 9.5 KDA SUBUNIT, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G08980)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0007534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="67" mass="7347" checksum="6DB17B86011E0324" modified="2023-09-13" version="1">MVLQYLKRSASQNPYIFVSFVIAAVGPALVVAVPSIRKSQGYVSPARIPETYPLPQRARNPPAGYED</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWA4</accession>
    <name>A0A9P6SWA4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_004084</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002122">
        <property type="protein sequence ID" value="KAG0007915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWA4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006376">
        <property type="term" value="P:mRNA splice site recognition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12344">
        <property type="entry name" value="RRM1_SECp43_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12345">
        <property type="entry name" value="RRM2_SECp43_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12346">
        <property type="entry name" value="RRM3_NGR1_NAM8_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000065">
        <property type="entry name" value="mRNA binding post-transcriptional regulator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000227">
        <property type="entry name" value="mRNA binding post-transcriptional regulator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000159">
        <property type="entry name" value="tRNA selenocysteine 1-associated protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050825">
        <property type="entry name" value="RBM42_RBP45_47-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47640:SF10">
        <property type="entry name" value="TRNA SELENOCYSTEINE 1-ASSOCIATED PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47640">
        <property type="entry name" value="TRNA SELENOCYSTEINE 1-ASSOCIATED PROTEIN 1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="70"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="165"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="310"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="286"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="287"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0007915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="485" mass="53354" checksum="F1E12FB109955924" modified="2023-09-13" version="1">MAFYEQLVQQQQQQQQQQQHQQQQQQQQQQQQQQQQQQLQLQHQLSQHPQHIQQFHQLQQPTYNNPDMRTSLWMGELEPWMDENWIRGVWYNAGEQVSVKMIRDKYTGASAGYCFVELSSPAAAIKAISTLNGMLIPGTNKTFKLNWATGGGVTPSSGPGASQEYSVFVGDLSPEVTEYMLVSKFQERYVSCRSAKIMTDATTGISRGYGFVRFSDESEQLRALLEMQGVYCGSRPIRISMATPKNKMPSSGMSGASTGNMGAVGGMGGIGGMGMNTNIGMSPASYGFSSPLQSGSPQHPANQSSDPSNTTVFVGGLSGVSHEDELRSCFAMFGEITYVKIPPGKGCGFVQFVHRQSAEMAINQMNGYQIGNSRVRLSWGRAQNENKRPLSPHAPSLVTPGFRSPLQSQFPGMPLNNRNSAPYGSFPGMLAGTPTFGMMQAAPSRDPIDRVPAEHQSRVYNDRKEAIMDRMDDGVAWRGSGAIYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SX07</accession>
    <name>A0A9P6SX07_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Anaphase-promoting complex subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ANAPC4</name>
        <name evidence="8" type="ORF">BGZ80_003329</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001875">
        <property type="protein sequence ID" value="KAG0008537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SX07"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034399">
        <property type="term" value="C:nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070979">
        <property type="term" value="P:protein K11-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024789">
        <property type="entry name" value="APC4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024790">
        <property type="entry name" value="APC4_long_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13260">
        <property type="entry name" value="ANAPHASE PROMOTING COMPLEX SUBUNIT 4 APC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13260:SF0">
        <property type="entry name" value="ANAPHASE-PROMOTING COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12896">
        <property type="entry name" value="ANAPC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0498">Mitosis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Anaphase-promoting complex subunit 4 long" evidence="7">
        <location>
            <begin position="134"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="425"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="478"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="432"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="496"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00016067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0008537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="542" mass="60775" checksum="1C0423B6DF0F34C7" modified="2023-09-13" version="1" fragment="single">MAPRRTQQQTLMARSMFAKNNTQIASGSGNAKDVQALAEKIDEPDEESSDIMNVLFVGDNKGWFRLKLFGDFETDLVSLLDLLRSYGIQGFQTIDILKTDIQLDLSELVVIALGSDCNPTKADNEGCGPQLLQITITSELLNKYSREIRVLGRKRGPVSHILKYLSDGLQVMQAEFRKISQLALDCVESVQQSLSDNGETTTPSYEFVQLLMTGLPSPSLDTYLQQELRRHGLRRWDKSVKAAYGSIQRVAFECLLPACERLLIHLTDILGCSRWDERYKPLNLHEALIYNCVRVVGDFVGMIERLFQVLKTETKNFHEFENWLEHVLEILQPTIREADEQGDSGLKSFPPVDYKSVSEFLQSGLSNKKLKGFFEDDEQVSEATKSQSYITKEEEILLGYDATPSYPIVYSFSEELQRIENAEKERVKETTELTAQELSSTPPVAPKNPFSGAAISAALASRGFGNLLQSKVPRLEPTNLFSKPKAPPSSHPLGASKRERPFSAHLGHEPPSLTLERHLQLMTKHCLSIFKGPAEAVAMSMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXN0</accession>
    <name>A0A9P6SXN0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001584</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001363">
        <property type="protein sequence ID" value="KAG0010333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXN0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="367"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="525"/>
            <end position="557"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0010333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="557" mass="63619" checksum="52AAA643D5BA8D26" modified="2023-09-13" version="1">MRLSTALLLVTDGIENAAYFQKGLSPLEYKAQDYFRSFRDKRSAHRTWSSVVIPRLIASKHEGLHQAGINLQKQWSKKSFQNELRKFWRQQDVITNSVQQHQTRILEHSYKDLCNNLESREAQFLGSTMTSTSHCEGLTGKNKAAVDGPIPVPAEETDNVEIEEDIEQASEEDVEQASEEDNDDNDDLLTFTSEDYRLFAEKYINIKDKDKFLLPSGRKLEEVLFSVGMTKKKHHLIHSFIIDVDDHDIECIFDSSDWESIVEEAEQQTCIADADVVTLLDSFKEMNSMKKIMERLSERHPRLGGSYVHSQDYDIKLDLYLFQPSIFSMEGLLEYFWRSNVWGVIDTLFYDTPNLLMVGGEGCGIESTQRRNQQQNKDNRKTSGSKSDGYLREFGANKADWMTIEGAKNWDPYCKKYKTESAWKLGRQLHDIFRARTTGMDQKKVLEFRTFGIVFGGILGGAATILRRRRPITLASSVRNFSHNIAILEVLLLLKSEIVRSIEMCTESPDAQTLFAGTSCTRHLQDGQDRATGSVPNAHRSPTKPTKKLKPIEAMTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXT2</accession>
    <name>A0A9P6SXT2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA endonuclease activator Ctp1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_002198</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001535">
        <property type="protein sequence ID" value="KAG0009642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXT2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010792">
        <property type="term" value="P:DNA double-strand break processing involved in repair via single-strand annealing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013882">
        <property type="entry name" value="Ctp1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033316">
        <property type="entry name" value="RBBP8-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15107:SF0">
        <property type="entry name" value="DNA ENDONUCLEASE ACTIVATOR CTP1 C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15107">
        <property type="entry name" value="RETINOBLASTOMA BINDING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08573">
        <property type="entry name" value="SAE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA endonuclease activator Ctp1 C-terminal" evidence="5">
        <location>
            <begin position="733"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="48"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="92"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="138"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="244"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="336"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="541"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="602"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="683"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="804"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="839"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="95"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="154"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="175"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="251"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="266"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="336"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="428"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="552"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="602"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="631"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="701"/>
            <end position="713"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0009642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="864" mass="97661" checksum="4918EDDACFF9A3A5" modified="2023-09-13" version="1">MRSRSLPPVPADVTHGPDELNSRPMQHRHENDDHDNVFISTTSAATTTAATPTLKIKTQSKRPSAIDATPGLMGPQLQECLAQAAQCAQDLQDRYQGSSSSSKGPVTGPSKQNDGDVCNESFSSFVSQSISQILDYMAPSNGSKEPKLPPLSKGSYSVANSTTSRDGGETEHTLRSALKSSSKSRPCTCGCQEEIKAWKARCDFAENQATLLEMRCEKTNIMMDAYKAKWTQWKETVVREQYQRRMKAAMSPQSARYMSLSSSKNQSQQQQQQQQQQQPQQNQQGQQGRRKKVFFTSDNTRRVRLGTEESNSSQKRQEVTERNTLFNQLITRVPEVSTTVRSSTPTNRALQTGTNSVSSPHVAFDDKDDNISSSNDDDATEEPVQRKPITYVLDSEENDTSVDYGEQPMSLTFPSDLALRRRGQGFSELEENDDDDDDDEDDGLDSSGREENRGFESSSRAQSKRRQYIDDSPTTRITERNQRRTAAISHRENLRRQQSPCTTDLCKVDDENTAGMLSIASDRSSPPMFDSEDYVTLYRSRKTSVKQDSDSAHTSLPHTPKSTSRNIQQDGSADRGRVFVPETPLELQGITPKKENEILTQSPLKPTSTHPNAVQQTSIPGGNLPNPMREATTNETESALHQYIQSQSPGGADESDKENKAPQVQAQVHEIHSSSDLEVYEKEDSFVEEGTCQGQGQGQRRSGEINHPKGRLQKQEQLRAQQAAIDVPEERIYNFTERRKDKRKQMHGHDCACCRRFYELTGPLPLPDGYNAFFTPAPRPGEKEVWEKSAEEKLQDRIQQISRHRVQHEEPLTPPGFWDTDFPSTQERIEWDKIAAERRERKKQRMEHQLQKQQQLQQQKRRRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXY3</accession>
    <name>A0A9P6SXY3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Cell cycle control protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_001138</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CWF19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001255">
        <property type="protein sequence ID" value="KAG0010851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXY3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040194">
        <property type="entry name" value="Cwf19-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006768">
        <property type="entry name" value="Cwf19-like_C_dom-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006767">
        <property type="entry name" value="Cwf19-like_C_dom-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12072">
        <property type="entry name" value="CWF19, CELL CYCLE CONTROL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12072:SF5">
        <property type="entry name" value="CWF19-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04677">
        <property type="entry name" value="CwfJ_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04676">
        <property type="entry name" value="CwfJ_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cwf19-like C-terminal" evidence="4">
        <location>
            <begin position="576"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="domain" description="Cwf19-like protein C-terminal" evidence="3">
        <location>
            <begin position="679"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="192"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="261"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="470"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="68"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="87"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="129"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="192"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="267"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="292"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="347"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="359"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="491"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0010851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="788" mass="90395" checksum="D9826B6B1E5EEA4F" modified="2023-09-13" version="1">MESTSRSSGSSHRREHDRKEGRERERDRDRDRDREKDRKHRHHDRDDRTEDRHKKHKPSSSSSKSRHHDRDDGDGGDRRHHSRSSSSRHDRDKERSGSSRRKEEKSTMDIDEDDEDMWVEREVPGVDQTPIQTKANESVGSGLVQSEVDQSQSASDIPVVADGDVSSKRDSWMMDDGGMDFGLMGALRVKKPKEEKPDPEKPHISSRELNVHLKTGLHVDQYPETEKPSYTIGDAGSSWRMTKLKRVLETAAEEGVTPEVIGIERYGSLEKFNEAMEERRELDRRASRKKDRRSDRADDSRDDRRDKRRGDDREDDRSRHEGEGRGDDGRSSNREDRPSPRSGRLSEFSSAASSPFQRPMDEQERLEKEIARRNREKEREKEQEKRYTPIPSPFATHVSSPIPNHSADPVMTPDQLNKLKAKAIRAKMLGLPDADALEKEYEQAQKAVADGSSQSAAAEVQRTVVISTMGRSSGASSPAHLGPGNKKVPGKKKEITHDEQGNRIAYQGEEAELDLHELVRREKLGLEEGMDKELARRITRDAVFRDDLDYMDENADKIARTVKKNDTQLKNAAIHDYRKTQSALDNCPLCFKDEGRSPPQMPVVSMGNRVYLGLPLYKEFLPGHCMIVPIQHVTSTLECDDDGWDEIRNFMKCLIQMNAAEDKFVIFSETEAILSADEEWSQHKKLIETDAKDSSNGGFRRRLTSKLPFFHVWFGSPDKGYGHVIENSDKFEEYFVKEVLASICEMDSLQWSRRNTKRIPAAENPRRVEAFKKSWQAWDWTRTLEGNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SY68</accession>
    <name>A0A9P6SY68_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">RNA polymerase II transcription factor B subunit 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">TFB1</name>
        <name evidence="9" type="ORF">BGZ80_001660</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TFB1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001385">
        <property type="protein sequence ID" value="KAG0010230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SY68"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000439">
        <property type="term" value="C:transcription factor TFIIH core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13229">
        <property type="entry name" value="PH_TFIIH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3970.10">
        <property type="entry name" value="BSD domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005607">
        <property type="entry name" value="BSD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035925">
        <property type="entry name" value="BSD_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027079">
        <property type="entry name" value="Tfb1/GTF2H1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013876">
        <property type="entry name" value="TFIIH_BTF_p62_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12856">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03909">
        <property type="entry name" value="BSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08567">
        <property type="entry name" value="PH_TFIIH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00751">
        <property type="entry name" value="BSD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140383">
        <property type="entry name" value="BSD domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50858">
        <property type="entry name" value="BSD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BSD" evidence="8">
        <location>
            <begin position="158"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="BSD" evidence="8">
        <location>
            <begin position="224"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="110"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="325"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="113"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0010230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="584" mass="65244" checksum="7FFC64F7FAAB7FD5" modified="2023-09-13" version="1">MNSILEPGEAIKIQAQAQFKKKSGTAYMTNRRLLWVPQEGLAATVTVRHDEIKGLFVNAEGSAKAIIKVVEMRPDISHSFVFTSTDAMKERNNFKGAISSILAERQLRTNTAASSPAGSPVVSDGSAPGTPKLSAQSKLGPGAGGVRRGLSGTGPSAELKAKFELLKQNKELVTLHKELVMGKHVSEEEFWESRKHLLRNKVAMDQQQKGQSSAWLDLKPETGESNDVKYVMTPQVIHSVCQQYPSIKRAYDTCVPDKLSEAEFWKRYFQSRFFHRSRSGRGANEPDDDIFDKALEEDEEETKHAPKRIKLDHINRLVDLSTTEEDHFESYTSPDSTMAAGKTKESKEAMPLIRRFNRYAQRVLNSTVGPKKPSATPEPLNMNGVERAIVLEDLQEQKEASRVALDIQDTRRYFESQGGGVKSSKIKEGQDPAEILERCYNDFINHEVELNKPFTIPKSTFDALMSNVKVNRAKMMPPKDGSQLLPSHLYQDALSCHAAGNEILRHFWASTTPDKAAKHMRMVESLKKIRDENIRSLIAQANALGEESVNSMKIILKPMQGAIAKALKHAETSRPKPMTPRRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYB6</accession>
    <name>A0A9P6SYB6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">DNA 3'-5' helicase</fullName>
            <ecNumber evidence="16">5.6.2.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="21">DNA repair helicase RAD25</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="20">RNA polymerase II transcription factor B subunit SSL2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="19">Suppressor of stem-loop mutation 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="25" type="ORF">BGZ80_000667</name>
    </gene>
    <organism evidence="25 26">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="25" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="25">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="18">ATP-dependent 3'-5' DNA helicase/translocase; binds dsDNA rather than ssDNA, unzipping it in a translocase rather than classical helicase activity. Component of the general transcription and DNA repair factor IIH (TFIIH) core complex. When complexed to CDK-activating kinase (CAK), involved in RNA transcription by RNA polymerase II. Also involved in transcription-coupled nucleotide excision repair (NER) of damaged DNA. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. The ATPase activity of XPB/SSL2, but not its helicase activity, is required for DNA opening. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. The ATP-dependent helicase activity of XPB/SSL2 is required for promoter opening and promoter escape.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.</text>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Component of the 7-subunit TFIIH core complex composed of XPB/SSL2, XPD/RAD3, SSL1, TFB1, TFB2, TFB4 and TFB5, which is active in NER. The core complex associates with the 3-subunit CTD-kinase module TFIIK composed of CCL1, KIN28 and TFB3 to form the 10-subunit holoenzyme (holo-TFIIH) active in transcription.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the helicase family. RAD25/XPB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="25">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.4" evidence="16"/>
    <dbReference type="EMBL" id="JAAAID010001142">
        <property type="protein sequence ID" value="KAG0011469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYB6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000112">
        <property type="term" value="C:nucleotide-excision repair factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005675">
        <property type="term" value="C:transcription factor TFIIH holo complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097550">
        <property type="term" value="C:transcription preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18029">
        <property type="entry name" value="DEXHc_XPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18789">
        <property type="entry name" value="SF2_C_XPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000077">
        <property type="entry name" value="Probable DNA repair helicase RAD25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000117">
        <property type="entry name" value="Putative DNA repair helicase rad25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050615">
        <property type="entry name" value="ATP-dep_DNA_Helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032438">
        <property type="entry name" value="ERCC3_RAD25_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001161">
        <property type="entry name" value="XPB/Ssl2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032830">
        <property type="entry name" value="XPB/Ssl2_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00603">
        <property type="entry name" value="rad25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11274:SF0">
        <property type="entry name" value="GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11274">
        <property type="entry name" value="RAD25/XP-B DNA REPAIR HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16203">
        <property type="entry name" value="ERCC3_RAD25_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13625">
        <property type="entry name" value="Helicase_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00851">
        <property type="entry name" value="XRODRMPGMNTB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="12" id="KW-0234">DNA repair</keyword>
    <keyword evidence="10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="26" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0804">Transcription</keyword>
    <keyword evidence="9" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="23">
        <location>
            <begin position="243"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="24">
        <location>
            <begin position="460"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="22">
        <location>
            <begin position="641"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="22">
        <location>
            <begin position="649"/>
            <end position="660"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00034617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00034808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00048988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00058901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00075489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00076598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00078607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="EMBL" id="KAG0011469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="660" mass="74228" checksum="96756C0A06F96486" modified="2023-09-13" version="1">MDVTTQPQLPQKDNVSYIFGDHDYTWLSPKNGHESRPLWVTQDGFIILEGFSSIAEKATDFLATIAEPVSRPSHIHEYKLTRQSLYAAASVGLEADNIIQALSLLSKVPVPESVIGLIRDRTLSYGKLRLVLRHGQHFVESSHPEMLQILLRDHVIRESLVANSENCGDDTTSAVGGLITTQGLDKSEDSAEGHPVESFKIRSSFLEAKEYDFKNDTVNPDLDFGLTPSTTIRPYQKTSLSKMFGNGRARSGIIVLPCGAGKTLVGIAASTTVKKSTLVLCTSSVSALQWKQQFLLWSNIKPNQIALFTSDHKAKFVGDAGIIISTYSMVASTGKRSHDSESMMDFLKSQEWGLLLLDEVHVVPADMFRKVLNTVVAHAKLGLTATLLREDEKIDHLSYLIGPKLYEANWADLASKGHIANVKCAEVWCTMTPQFFTHYLQESSSRRRMLLAVMNPSKFQACQFLIRYHEERGEKIIVFSDNVYALKMYARILGKPFICGETSQPERVQILEHFQHNPQINTIFLSKIGDTSIDLPVATCLIQVSSHYGSRRQEAQRLGRILRARRRNDEGFNAYFYTLVSKHTQEMYYSTKRQQFLKDQGYAFKVITDFEEINQEQDLVHSTPDEQASLLDMVLKVHESEGGQSEVGQNEEMELDNGQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYT6</accession>
    <name>A0A9P6SYT6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_011753</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000986">
        <property type="protein sequence ID" value="KAG0012425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYT6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0012425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="256" mass="28477" checksum="56F2F062232C1528" modified="2023-09-13" version="1">MPTSEKSPTPDFMPLEVIDQMDKSAVSVTAFVKQLRSLNITKLAEHEKKEYLDIVGQYEDILESLLTYIGNEKPKFEYLQVAVVKDRKQALGTKRRDKVLRLVVMGGAGVCLLVASITTALITLASAGAATPLIVPIITTAFTIFSGLGGFKLILDIIQHGTENAKLTVIDNNLATLEKHLGDVRVKCDELKNANRLFSFDMRTKNFNVIDHDHIQIVEAYVSQSNNFTGDQCHMCRLMIICKRLAKIEDVIRNGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYW1</accession>
    <name>A0A9P6SYW1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Peptidyl-prolyl cis-trans isomerase</fullName>
            <ecNumber evidence="12">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">PIN4</name>
        <name evidence="15" type="ORF">BGZ80_011788</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 17">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Spindle</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
            <location evidence="3">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PpiC/parvulin rotamase family. PIN4 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="12"/>
    <dbReference type="EMBL" id="JAAAID010000993">
        <property type="protein sequence ID" value="KAG0012374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYW1"/>
    <dbReference type="OrthoDB" id="1911748at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005819">
        <property type="term" value="C:spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.50.40:FF:000015">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043323">
        <property type="entry name" value="PIN4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000297">
        <property type="entry name" value="PPIase_PpiC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45995">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13616">
        <property type="entry name" value="Rotamase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50198">
        <property type="entry name" value="PPIC_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9 11 12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11 12" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PpiC" evidence="14">
        <location>
            <begin position="34"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU363014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0012374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="131" mass="14105" checksum="08C57FF54C7470DF" modified="2023-09-13" version="1">MPPKPANKKAPAPKGKKGGNDDDDSKGGKSLKTANSIKVRHILCEKQSKALEAIEKLKAGIAFNKVAEAFSEDKAKDGGSLGWMVRGSMVGAFQDAAFQLQPSTTAKPIYTDPPIKTQHGYHVIMVEDRKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZG8</accession>
    <name>A0A9P6SZG8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Pheromone-regulated membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_011201</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the ThrE exporter (TC 2.A.79) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000872">
        <property type="protein sequence ID" value="KAG0013254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZG8"/>
    <dbReference type="OrthoDB" id="413008at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010619">
        <property type="entry name" value="ThrE-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051361">
        <property type="entry name" value="ThrE/Ser_Exporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024528">
        <property type="entry name" value="ThrE_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31082">
        <property type="entry name" value="PHEROMONE-REGULATED MEMBRANE PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31082:SF4">
        <property type="entry name" value="PHEROMONE-REGULATED MEMBRANE PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06738">
        <property type="entry name" value="ThrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12821">
        <property type="entry name" value="ThrE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="611"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="634"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="695"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="739"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="763"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="790"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="813"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="850"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="domain" description="Threonine/serine exporter-like N-terminal" evidence="8">
        <location>
            <begin position="478"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="domain" description="Threonine/Serine exporter ThrE" evidence="9">
        <location>
            <begin position="742"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="226"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="278"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="352"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="28"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="80"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="99"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="247"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="297"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="317"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="354"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00034125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF06738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0013254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="884" mass="96123" checksum="B616B741F95799EF" modified="2023-09-13" version="1">MSANSTPSHTPPQRPQFTSAPSTPPQRPQSTSVSPTPTLSTPSTNPNPTPPVIAANLPPSHSHHTLGVNHGERTHRPMPTASTQWSNNRYNPPVPSRMSGVYSSNNSVYNGNLSPSGRRFGTHSASNSPPGTPPNGLRDYYLNIAYQRSQNRLYPPGSPASSNLNLLRPGLNTVQPQHDSPLRRSYSADNLAVDEPEITITGPDGSSSTEEHATALQKVLSDLVQSEGRASIDADDHDEEGPVMMKGSNSSSATKTGSAANKEGVLLTPKVLANRLVSERTDVTPVNEPAEKEKKQTKEKHKSHNRISKLFNREAPATNTAPEQVHTTSQPARVPIQPSKAGVLSNLLKLQGGTRHKTHTTHSKQHKEKEKKRRSALYSRSANTSVISLSSKPLFGPYPIPPTSTTAVANHRNGNGYFDPHITAFAQGHSPIHSPGDSPRESISQDYFMSGASTLHSLSHEEKMRITFAVADILKRQDYVLRLARAMIKYGAPSHRLEEAIDHTARTLELNMQCVYMPNVMIVAFTDYETHTSETHLLKVSAGLNMHKFAQVHQVLKMVTHSSMPVEEAIMKLDAINTEKDIWPRWANILSFAIASFCTAPMFYKGNWIDAVVAGALGVFVGLMSWLSERLPSYAHICEVTMSVFVSFIAESLHSYICRSAVKMGGTVMLLPGYTITTAILELSSRHMISGSVRLFYAIIYSLLLGYGLTIGASLWNLIDSGSTPAGVTGDCPTTLSPAWNILFVPLFAFSLNIYLKLHPRQWVLATILAVIGYVVSYALSTWTGAKTEVSSALASFSIGFVGNVYQRMTHQLTFPGVICAVFFLVPGSLGLKGAMAWFTDDTTGGVNFALQMVITAIAISVGLFGSALVVYPMGKSRSAQMTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZR9</accession>
    <name>A0A9P6SZR9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Autophagy-related protein 16 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_011241</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATG16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000880">
        <property type="protein sequence ID" value="KAG0013188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZR9"/>
    <dbReference type="OrthoDB" id="538223at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034274">
        <property type="term" value="C:Atg12-Atg5-Atg16 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000421">
        <property type="term" value="C:autophagosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034045">
        <property type="term" value="C:phagophore assembly site membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043495">
        <property type="term" value="F:protein-membrane adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22887">
        <property type="entry name" value="Atg16_CCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045160">
        <property type="entry name" value="ATG16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013923">
        <property type="entry name" value="Autophagy-rel_prot_16_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19878">
        <property type="entry name" value="AUTOPHAGY PROTEIN 16-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19878:SF8">
        <property type="entry name" value="AUTOPHAGY-RELATED 16, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08614">
        <property type="entry name" value="ATG16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Autophagy-related protein 16" evidence="7">
        <location>
            <begin position="20"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="270"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="312"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="354"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="411"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="439"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="497"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="221"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="51"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="222"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0013188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="568" mass="63630" checksum="FE069CCA6FE92188" modified="2023-09-13" version="1">MTTAYHQSTQQWEADILGLFANRDKHEKAFTNMVDSYNELVQKLSYYVEQNKHLESTTQNAKDQHEKMARQVTVLREQGSPMNQKRSAELEAQVASLKDERAELYKTQGTNAQRLLDLNDILRNKDATLAQNKEEIRRLTEANTIFAHKNQDMQERLNEKNVTIQVIQDELQTLQLEMGKLDERQRELERENAQLLQRWLKMKNEEADRMNAANVFLENEQQETASLSQPVQSPGTRSLRSVGPDSPTQSNWRGQSTIFSIIPQISSRKITTHDSEVNTVAMSNGGTVFATGSNDKKIKIWDVKTGALKSTLTGCLQAVMCVSFNATDELLLGASNDNAARLWHLGTGRPRHTLTGHIGKVFSARFNPDSSKVVSGSHDRTIKVWDLQKGYCIRTMFTFASVNDVCLLDFDGSTIASGHLDNNLRFWDARSGNCVKEVTGIHVGQITSVCPSSDGTQILTNSRDNTVRILDVRTYETLSVLHADGYKTGTNWSKACFSPDGQYVVSGSADGTLYYWSTRDGTVEKTTKEQSGPIVGVSWSNSTVVSAEKDKTVVIWGTTARRPTVYEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZS0</accession>
    <name>A0A9P6SZS0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_010798</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000792">
        <property type="protein sequence ID" value="KAG0013870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZS0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039169">
        <property type="entry name" value="Abitram"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13651">
        <property type="entry name" value="PROTEIN ABITRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13651:SF0">
        <property type="entry name" value="PROTEIN ABITRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="169"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0013870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="244" mass="27087" checksum="4EE0C6120380429B" modified="2023-09-13" version="1" fragment="single">MDEHAPIVYDLTQYKEETKNWGSDPSAYLLRYYTKYYFLATGGKDLKQSSTQKIIDQQTGLEILRGDQFVYQSPNKLCITGLAPTHPLLAQKDRYKVINLRFDQKILSSLPQPTAIPANSKKQPPPPCHCDTVICKIEAFDLWAKKEQDAKSETLPSVDSDSAAEAEVEATPAAAGADAATPKPIASDNTQGEKKPKESIDPSRVIFVIRGAISGHVIELNERLLKRDTPEITDTSVIQIMIEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0E5</accession>
    <name>A0A9P6T0E5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_009566</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000586">
        <property type="protein sequence ID" value="KAG0015878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0E5"/>
    <dbReference type="OrthoDB" id="1939598at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14705">
        <property type="entry name" value="bZIP_Zip1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13044">
        <property type="entry name" value="ACTIVATING TRANSCRIPTION FACTOR ATF 4/5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13044:SF14">
        <property type="entry name" value="CRYPTOCEPHAL, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07716">
        <property type="entry name" value="bZIP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BZIP" evidence="8">
        <location>
            <begin position="346"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="88"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="131"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="251"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="434"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="367"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="133"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="157"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="181"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="267"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="304"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="453"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0015878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="462" mass="50576" checksum="913CDF6434F8F75A" modified="2023-09-13" version="1">MDSYPNPYAALIATFNQVSPLESKDDLDDPQHLPDDDLLLWANAQFTYDIPPGVGIYEDDMGVKLAMSQQQFQQTQQQQQQQQQQQQQFQQPQQQSHSIMTSQTQQQQSLQYQSSDMQRQLQQFDAIHRYLDASSSSEDPRTSLSVVERSRQRNPVSGTTTTGPSQAATTSIHYNGLNPIYPQQQSHSESLPFSSAAASTATAAGPISPAAARLLRQQPFLTLHQQSYSATSSPLSSPTTVSDFHQLQINSPLPVISPKPSEDASSVKRSPSSRSESVSIKSPVSSSLPAAAIAASLEEKSNQDDSDDEDYENDKDISSKSTKIPKAIQGLSPDDPEYAAKLAAEEDKRRRNTAASARFRHKKRLREQILEKTAKEMTAKSELLEARVRELEMEIKWLRGLIVEKDSRMLDAAISSSSSTASSLSIATSALSALSSSSSVKDVGDSASSTPAPKKRGKKTKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0G3</accession>
    <name>A0A9P6T0G3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Aquaporin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_009835</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000625">
        <property type="protein sequence ID" value="KAG0015477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0G3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015250">
        <property type="term" value="F:water channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="entry name" value="Glycerol uptake facilitator protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034294">
        <property type="entry name" value="Aquaporin_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19139">
        <property type="entry name" value="AQUAPORIN TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19139:SF199">
        <property type="entry name" value="MIP17260P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="Aquaporin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0015477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="166" mass="18356" checksum="3176858C4BB65F89" modified="2023-09-13" version="1">MITGRISFVKFVAYFASEILGAMLGVACVRGTSPSSERNNMVIDIQHGESMARAFFLEFFLSSIMCFVYHITFHEKNHPMFLVAIPNGFAYFACHLITVLIVSAKLLTLRFVSSRPLCGGVSAAALHIPLRYFGFGRHSAGIDAEDHEQYARARAAYKGEQSSGDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0L8</accession>
    <name>A0A9P6T0L8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_009495</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000575">
        <property type="protein sequence ID" value="KAG0016006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0L8"/>
    <dbReference type="OrthoDB" id="2437169at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="221"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="226"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="272"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0016006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="353" mass="39650" checksum="6C5639AF72857F42" modified="2023-09-13" version="1">MPAYAKKFNYTQSTSAEGPYLKLIGSSNITLTRRQHLRTEYDTFKANEAKQYWESVQFKLSLKSTARKAATSTAEAGLYELQAEYSTYKEGSGDHASECIDLSPSSVSQVNRRLLPTGDKTTSSSSLPPIASDFSMDRMPNNEVADDTKIFISESQFDENDDVDNCKAAFKRYTSSLLAISQKQAINKVIRICAKEARDVRESHFRTHYFKKDSEIVQAAANRKRPACDQDHPSKQSRYESDEESDDTCLHLDLLNNNPIPSDPDDTDYLPSSQPSSQSSQYDSESSNEDLTGELFVPVKADHLVGPGTFSSQLTDDLEGRLIVEDLDISDSIMKYRRKRVIKEGLLEKDDLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1A5</accession>
    <name>A0A9P6T1A5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">phenylalanine--tRNA ligase</fullName>
            <ecNumber evidence="5">6.1.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Phenylalanyl-tRNA synthetase beta subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="primary">FRS1</name>
        <name evidence="17" type="ORF">BGZ80_008437</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>tRNA(Phe) + L-phenylalanine + ATP = L-phenylalanyl-tRNA(Phe) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19413"/>
            <dbReference type="Rhea" id="RHEA-COMP:9668"/>
            <dbReference type="Rhea" id="RHEA-COMP:9699"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58095"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78531"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.20" evidence="5"/>
    <dbReference type="EMBL" id="JAAAID010000457">
        <property type="protein sequence ID" value="KAG0017292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1A5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009328">
        <property type="term" value="C:phenylalanine-tRNA ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004826">
        <property type="term" value="F:phenylalanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006432">
        <property type="term" value="P:phenylalanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00769">
        <property type="entry name" value="PheRS_beta_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000059">
        <property type="entry name" value="phenylalanine--tRNA ligase beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.40.10:FF:000002">
        <property type="entry name" value="phenylalanine--tRNA ligase beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.56.10:FF:000004">
        <property type="entry name" value="Phenylalanyl-tRNA synthetase, beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.56.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.40.10">
        <property type="entry name" value="Phenylalanyl-trna Synthetase, Chain B, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005146">
        <property type="entry name" value="B3/B4_tRNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045060">
        <property type="entry name" value="Phe-tRNA-ligase_IIc_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004531">
        <property type="entry name" value="Phe-tRNA-synth_IIc_bsu_arc_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020825">
        <property type="entry name" value="Phe-tRNA_synthase-like_B3/B4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041616">
        <property type="entry name" value="PheRS_beta_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040659">
        <property type="entry name" value="PhetRS_B1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005147">
        <property type="entry name" value="tRNA_synthase_B5-dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00471">
        <property type="entry name" value="pheT_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10947:SF0">
        <property type="entry name" value="PHENYLALANINE--TRNA LIGASE BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10947">
        <property type="entry name" value="PHENYLALANYL-TRNA SYNTHETASE BETA CHAIN AND LEUCINE-RICH REPEAT-CONTAINING PROTEIN 47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03483">
        <property type="entry name" value="B3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03484">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18262">
        <property type="entry name" value="PhetRS_B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17759">
        <property type="entry name" value="tRNA_synthFbeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00873">
        <property type="entry name" value="B3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00874">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56037">
        <property type="entry name" value="PheT/TilS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="Putative DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51483">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 17" id="KW-0436">Ligase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="B5" evidence="16">
        <location>
            <begin position="307"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00033189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0017292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="602" mass="67868" checksum="23DC91769F2F1151" modified="2023-09-13" version="1">MPTVNVDKEELYTALGRTYTFDEFMDLCFNFGIELEEDTSPKEMAIREVGAHKVDESVSDRPILKIDIPANRYDLLCHEGISRSLLIFQGKTKPPVYKIVNPPAGQALQKMIVKPETTRIRPFVVCAVLRNIKFTELNYKNFIDLQDKLHTNICRKRSLVAIGTHDLDTLKGPFTYEALAPKDIQFMPLNQEKNMNGEELMTFYESDKHLSKFLPIIRDSPVYPIIYDSTRQVLSLPPIINSNHSKITLDTKNVFIECTATDLTKGKIVLNTMVAMFSEYCAEPFTVEPVEIIYEDNRQPKGVTPDLASRTTTAKVDYINSCTGLKLSPESICDLLNKMSLEATPSKEDKNEIVVQVPVTRSDVLHQCDIMEDVAIAYGFNNLPHTAPSVSTIGKPYPLNKLADVARLEMALAGWSEVSPLTLCSHDENFTFLRQKDPGNIAVRLAHPKTIEYQVVRTSLLPGVLKTLKENKKHSLPIKIFEVGDTAIKDDAMERRSRNIRKVCATYSNKTSGLEQIHGLLDRVLQMLHSQPTDKNGTGTGYWIEESSNPTYFPSRSADIYLRQKGETKVIGSFGILHPEVLEKFGINFPTSALEFDLEPFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1T3</accession>
    <name>A0A9P6T1T3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_008009</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000422">
        <property type="protein sequence ID" value="KAG0017694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1T3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016628">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05288">
        <property type="entry name" value="PGDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000121">
        <property type="entry name" value="Prostaglandin reductase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045010">
        <property type="entry name" value="MDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43205">
        <property type="entry name" value="PROSTAGLANDIN REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43205:SF7">
        <property type="entry name" value="PROSTAGLANDIN REDUCTASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="2">
        <location>
            <begin position="37"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0017694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="291" mass="31828" checksum="F29BE2120F792F5C" modified="2023-09-13" version="1">MISSTYSYISSYEINGAFNSYGISEVVETKNAKFPVGTLVTSPYIRWEEQTVLPSSIAKDLTILPAEVRDSKIPLSAYIGVLGMHSFTAYGSLLDIGQPKAGETIYISAASGAVGQLVGQIARLKGLRVIGSVGSDDKVDYLLKELRFDAAFNYKKEKIVDSLRAAAPEGIDIYYENVGGEALEAALEVLKPHGRIIACGMVSGYNSGEGYNVKNLFQIVTKRLTIKGFLVVDFNEELNERFRKDVSEWILNGDIVYKEDITEGLDDAPEAFVGLFHGKNFGKALVKITDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1Z0</accession>
    <name>A0A9P6T1Z0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 16 17">Phosphatidate cytidylyltransferase</fullName>
            <ecNumber evidence="6 16 17">2.7.7.41</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">BGZ80_006839</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 16 17">
            <text>a 1,2-diacyl-sn-glycero-3-phosphate + CTP + H(+) = a CDP-1,2-diacyl-sn-glycerol + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:16229"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
            <dbReference type="ChEBI" id="CHEBI:58608"/>
            <dbReference type="EC" id="2.7.7.41"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 16 17">Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 16 17">Belongs to the CDS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.41" evidence="6 16 17"/>
    <dbReference type="EMBL" id="JAAAID010000340">
        <property type="protein sequence ID" value="KAG0018716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1Z0"/>
    <dbReference type="OrthoDB" id="10260889at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004605">
        <property type="term" value="F:phosphatidate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016024">
        <property type="term" value="P:CDP-diacylglycerol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000374">
        <property type="entry name" value="PC_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016720">
        <property type="entry name" value="PC_Trfase_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13773">
        <property type="entry name" value="PHOSPHATIDATE CYTIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13773:SF8">
        <property type="entry name" value="PHOSPHATIDATE CYTIDYLYLTRANSFERASE, PHOTORECEPTOR-SPECIFIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01148">
        <property type="entry name" value="CTP_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018269">
        <property type="entry name" value="PC_trans_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01315">
        <property type="entry name" value="CDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 16" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="12 16" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="13 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 16 17" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14 16" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="15 16" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 16 17" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 16 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="87"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="181"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="210"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="234"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="280"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="355"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="37"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="47"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRNR" id="PIRNR018269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU003938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAG0018716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="476" mass="53597" checksum="D7861B791BA62671" modified="2023-09-13" version="1">MTKTKSPKRSSPPSSSNGHHTHVASISKASDPVASAAVTTTSEKGASSNNNGLHNNGSGPTPAAKEVTLLVDESNKAKWANWSVRTLWTLIMIGGFFACVAAGPLFVILLVVMVQGLVYKEVIYLAAVPSREKKLPWFRAMNWYFLFSTNYFFYGESLIHYFQHVVFVDAFLLPFATHHRFISFTLYVIGFVFFVANLKKGHYRFQFSQFAWTHMTLLLVVCQSHFIINNIFEGLIWFFLPVSLVITNDIFAYIFGFFFGRTPLIKLSPKKTVEGFVGGWIMTIVFGMLFATLFLRYPYMICPVKDLRSTAFSGLTCEPNAVFVPVKHYLKPWMVGLVRHLGIRSNYVMLAPLQLHTIVMACFASLIAPFGGFFASGFKRAFKIKDFGQSIPGHGGITDRMDCQFLMGLFSYMYYQSFIKSSAVTVGFVLQNAINLSAHEQMELFDHLRQYLIGQGLLDEESCIVMPPKEAWVNVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T224</accession>
    <name>A0A9P6T224_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">PHD-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_005981</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000295">
        <property type="protein sequence ID" value="KAG0019326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T224"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058923">
        <property type="entry name" value="RCC1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028641">
        <property type="entry name" value="RCC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46207">
        <property type="entry name" value="PROTEIN RCC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46207:SF1">
        <property type="entry name" value="PROTEIN RCC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25390">
        <property type="entry name" value="WD40_RLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00626">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="repeat" description="RCC1" evidence="6">
        <location>
            <begin position="84"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="6">
        <location>
            <begin position="144"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="6">
        <location>
            <begin position="207"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="6">
        <location>
            <begin position="315"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="8">
        <location>
            <begin position="386"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="438"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="447"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="457"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0019326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="484" mass="52258" checksum="F7003CE26ECF4ACB" modified="2023-09-13" version="1">MAASTTDQPTWGKVLIAGGVDWDMIGRKPKAGEVPSTNTDIETLSSYRPHLETFHIIRELTDLKIVKIATGPNAAHSVFLTDDGDAWVLGRNEKGQLGLGDTDPHPYPVKVPTIYTTVGKKTSNVKFVNAAVGRNHTILIADNGAVYGAGDNKMGQLGNKTNGQYLQQSNRLVHIPQTSPVLVAALKDKVVTQVVCGTNHTLALADGIVYSWGFGGYGRLGHSKQEDLWSPMPIEQFAGSNKITRATKIAAGSSFSMALDGQNQFWLWGKWKTTGDGGGGTPWMYPRTLYDLNGWSFKSIGGGNVTLFCIPSVEPCTIAWGQGAVHSELGYGEGEARSSTKPDKIRPLEGLTMMDVSCGLGHSLLLCKPGQEKLQDLPKWPVLDVEEHCIECLSAEDEDSMLLCDKCDSGTHLQCTVPRLQEVPDVDWFCQSCTKAREMNKTKQSGDDSSSSPAKASAKRKAPAAKGSSKKSKANRSSDDEDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2B4</accession>
    <name>A0A9P6T2B4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RNA recognition motif domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_005195</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000258">
        <property type="protein sequence ID" value="KAG0019833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2B4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000382">
        <property type="entry name" value="G-patch domain-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040052">
        <property type="entry name" value="RBM17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003954">
        <property type="entry name" value="RRM_euk-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13288:SF8">
        <property type="entry name" value="SPLICING FACTOR 45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13288">
        <property type="entry name" value="SPLICING FACTOR 45 SPF45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00361">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RNA recognition motif" evidence="7">
        <location>
            <begin position="414"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="189"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="400"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="18"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="85"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="189"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="206"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="266"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0019833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="501" mass="54997" checksum="4F20F91874E13960" modified="2023-09-13" version="1">MSLYGDLPPPGSSADSENALKKQASDSKDGSNSSTSAKPVLPAGWSSSITRFKPMLNRKLPPPKSKPTARSIPAGFVAQTPEKQSITASVSLSSGSSAPLPTAGTPQSQSTPQQTPESTVDENSWLKARTAQVQRQDIDGLASIRKQMKKPPSKGQPGPISLDDDYDIARPNEYQEFKLLFEDEQRAKIEEEQRSREEARTAGRGSRSRSNSRRRSWSPPMDGGHIRNSHNREHSRSPSPRAHASGRGHNYHPARETPSSTAPYQRARRSRSRSKSPRSWRNERDKSRSPSPSFSRRHTHRQSPSPPRNESIGGHGRAPAYKAFAPPPDLAAESHSKAPDGGRGTVPAAPQNILNDVSGEDAYLRRARLSQQRATATTTPLQPQPSLQNHVSPIREQHGRGAFASTTHQASSKGPGEVDDTLQEETAGECEKYGSVVRCLIFEVQNGKVPPEEAVRIFVKFGAIPSAERALRDLDGRFFGGRQVHCQFFDERRFDLLQLAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2L1</accession>
    <name>A0A9P6T2L1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cyclin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004871</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000244">
        <property type="protein sequence ID" value="KAG0020039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2L1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20557">
        <property type="entry name" value="CYCLIN_ScPCL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="256"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="314"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="27"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0020039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="401" mass="43890" checksum="9789026501CFBA8C" modified="2023-09-13" version="1">MDSGKVEYRTVVSRWEPTIPTPDAETASENASAVSGSSSTISHAARLMSLANYIRHILSLTVAVPNAQPQAHARQQQVKDEPRNQDSNTPSSNSSSGSTASSSGPGPIKSESNRRHRFSPAYHHHPARRSTHHSERGSSSTQYHSEYPGYREGNYTSESRETSQNYPRASYDASHTQQPTSILPPLLKIPFPNLTLTLALIYVDRLKAKYPKVKGEPGCSHRLFLVAFIIAAKYRCSVELSPPVSQDLDGVDQEQEIGSYRNNPDGEGIEDDGRSNQSLDARLNAELIFSNHAWVRLLNLGSFYRQPSADAAASSSSATENREQSSSAQPSHSAQAIESLPPLSSIINNAASSPVTGMLQVEDLDRMEAEFLTFLQLDLATMSHDLETCWNLLVGKSEAQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2M9</accession>
    <name>A0A9P6T2M9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Signal recognition particle 54 kDa protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">SRP54</name>
        <name evidence="15" type="ORF">BGZ80_004250</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Signal-recognition-particle (SRP) assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum (ER) membrane. SRP is required for the cotranslational protein translocation for ER import and preferentially recognizes strongly hydrophobic signal sequences. It is involved in targeting the nascent chain-ribosome (RNC) complex to the ER and is proposed to participate in the arrest of nascent chain elongation during membrane targeting. SRP54 binds to the signal sequence of presecretory protein when they emerge from the ribosomes. SRP54 interacts with the scR1 RNA and mediates the association of the resulting SRP-RNC complex with the signal recognition particle receptor (SR) via its alpha subunit SRP101. Both, SRP54 and SRP101, are locked in their GTP bound forms in the SRP-RNC-SR complex, which dissociates upon transferring the signal sequence to the protein-conducting channel (translocon). After signal sequence transfer, SRP54 and SRP101 act as reciprocal GTPase-activating proteins (GAPs), thereby resolving their association.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.4"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="13">Fungal signal recognition particle consists of a 7S RNA molecule (scR1) and at least six protein subunits: srp72, srp68, srp54, sec65, srp21 and srp14.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 13">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 13">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="13">The M domain binds the 7SL RNA and the signal sequence of presecretory proteins.</text>
    </comment>
    <comment type="domain">
        <text evidence="13">The NG domain, also named G domain, is a special guanosine triphosphatase (GTPase) domain, which binds GTP and forms a guanosine 5'-triphosphate (GTP)-dependent complex with a homologous NG domain in the SRP receptor subunit srp101. The two NG domains undergo cooperative rearrangements upon their assembly, which culminate in the reciprocal activation of the GTPase activity of one another. SRP receptor compaction upon binding with cargo-loaded SRP and GTPase rearrangement drive SRP-mediated cotranslational protein translocation into the ER.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the GTP-binding SRP family. SRP54 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000219">
        <property type="protein sequence ID" value="KAG0020399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2M9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005786">
        <property type="term" value="C:signal recognition particle, endoplasmic reticulum targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008312">
        <property type="term" value="F:7S RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030942">
        <property type="term" value="F:endoplasmic reticulum signal peptide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006616">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane, translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17875">
        <property type="entry name" value="SRP54_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000022">
        <property type="entry name" value="Signal recognition particle 54 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.140:FF:000001">
        <property type="entry name" value="Signal recognition particle GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.140">
        <property type="entry name" value="Signal recognition particle SRP54, nucleotide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.30">
        <property type="entry name" value="Signal recognition particle, SRP54 subunit, M-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036891">
        <property type="entry name" value="Signal_recog_part_SRP54_M_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013822">
        <property type="entry name" value="Signal_recog_particl_SRP54_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004125">
        <property type="entry name" value="Signal_recog_particle_SRP54_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036225">
        <property type="entry name" value="SRP/SRP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022941">
        <property type="entry name" value="SRP54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006325">
        <property type="entry name" value="SRP54_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000897">
        <property type="entry name" value="SRP54_GTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042101">
        <property type="entry name" value="SRP54_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01425">
        <property type="entry name" value="SRP54_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11564">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 54K PROTEIN SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11564:SF5">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE SUBUNIT SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00448">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02881">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02978">
        <property type="entry name" value="SRP_SPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00962">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00963">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47364">
        <property type="entry name" value="Domain of the SRP/SRP receptor G-proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47446">
        <property type="entry name" value="Signal peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00300">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 13" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 13" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 13" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="8 13" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="10 13" id="KW-0733">Signal recognition particle</keyword>
    <feature type="domain" description="SRP54-type proteins GTP-binding" evidence="14">
        <location>
            <begin position="269"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU364034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS00300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0020399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="362" mass="39654" checksum="1C77A110546280C1" modified="2023-09-13" version="1">MVLADLGRRINGAIQSMSKANVVDDKVVDDMLKEISNALMESDVNIKLVMNLRKNIKSSITLDENTGAGNKKRNIQKAVMDELTRLVDPGVEPWKPKKGKSNVIMFVGLQGSGKTTTCTKLASFYQRKGWKTCLVCTDTFRAGAFDQLKQNATKAKIPYYGSYTETDPVQLAHEGVSKFKKENFEIIIVDTSGRHKQEQELFNEMQQISSAVNPDSTIFVMDGTIGQAADGQARAFKEAANVGSIIVTKMDGHAKGGGAISAVAATQCPIIFIGTGEHMHDLERFAPGPFISKMMGMGDISGLMETVQDLKLDQNKDLMKKLEQGQFSIRDMYEQFTTILKMGPLSKVMGMMPGIPPELLAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2Q3</accession>
    <name>A0A9P6T2Q3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Sulfite oxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_003563</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000195">
        <property type="protein sequence ID" value="KAG0020805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2Q3"/>
    <dbReference type="OrthoDB" id="10051395at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030151">
        <property type="term" value="F:molybdenum ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008482">
        <property type="term" value="F:sulfite oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006790">
        <property type="term" value="P:sulfur compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.420.10:FF:000002">
        <property type="entry name" value="sulfite oxidase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.650">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.420.10">
        <property type="entry name" value="Oxidoreductase, molybdopterin-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005066">
        <property type="entry name" value="MoCF_OxRdtse_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008335">
        <property type="entry name" value="Mopterin_OxRdtase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000572">
        <property type="entry name" value="OxRdtase_Mopterin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036374">
        <property type="entry name" value="OxRdtase_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19372:SF7">
        <property type="entry name" value="SULFITE OXIDASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19372">
        <property type="entry name" value="SULFITE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03404">
        <property type="entry name" value="Mo-co_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00174">
        <property type="entry name" value="Oxidored_molyb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00407">
        <property type="entry name" value="EUMOPTERIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56524">
        <property type="entry name" value="Oxidoreductase molybdopterin-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidoreductase molybdopterin-binding" evidence="5">
        <location>
            <begin position="105"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="Moybdenum cofactor oxidoreductase dimerisation" evidence="6">
        <location>
            <begin position="293"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0020805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="421" mass="47647" checksum="848C981DC47AC903" modified="2023-09-13" version="1">MELRQNNTHEYVQPPQHLKKELCDLDYLQDPPRILSNYLVHAPKPFNAEPHLPLLINSGEITPTDVFFKRNHGPIPDIHLEDHRVYIGIQQATQDCRGHPSRVEWKALDMKDIMTKWPKATITASLQCAGNRREGLAQVKEVKGVIWKAGTISNAVWSGPRLCDILKSVAGVPDDLHHEMIRNFHVSFEADDHVKEDACYGSSIPLRKAMDPLGDVILAYEMNGRPLTRDHGYPLRVIVPGYIGARSVKFLQKIIVQPQESTSFFQKLDYKILPPWVDATNVDSAWDLSPSLGEMNVQCVICTPMEREIIPCSKAITVKGYAIAGGGRAIYRVELSTDGGKTWEAVDKLEQTPDKVSGMYWAWALWEKKVPKFNTSSQLVARAYDSSGNMQPEFPIWNYRGVMNNSWFRVSNITQLPQSNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3A2</accession>
    <name>A0A9P6T3A2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Oligopeptide transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_002363</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000158">
        <property type="protein sequence ID" value="KAG0021446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3A2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035673">
        <property type="term" value="F:oligopeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045035">
        <property type="entry name" value="YSL-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31645:SF3">
        <property type="entry name" value="OLIGOPEPTIDE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31645">
        <property type="entry name" value="OLIGOPEPTIDE TRANSPORTER YGL114W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="69"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="95"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="134"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="233"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="282"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="308"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="342"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="411"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="436"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="526"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="585"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="618"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0021446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="666" mass="71057" checksum="2B2C02866BF91C5D" modified="2023-09-13" version="1">MKIKHSYSPLSSSCSPDTISGSTISSSDQEKALRSDYHKEKNDFIIEEDPIEILENIDEEEFIYEPQQFTWRASIVGSLLGCVVAASNLYLGLKIGWTFGAALWGSIFGFLILKSLSRFTGTIFGPKENTICQTAATAAGGLSNGFVTAIPAMYRMGLMGDGTPQDDIIDLSFWTISAAFFGMFFAIPLRSHFVINQDLVFPTPRAAAETIKNLHRAGSAAAKDARESGLTMIISFIGAMVWAIIGFFIPGIFGSIHILYYIGKAASYTAMMSADAEWGWNFTWDWAFFGAGLMTPASTVFSFMLGEIIAFGIAGPIMTSSGYLTGRIGFPPPPAVGSAQSWFLWPGVGMMVFTAFSELGANGPALYHGVMGGVREICNVFRKLQKKSALVDTSGYISKDTTPEHELIPTWWWLSGLVISAIFTVLVMWFNFKVPVYATVGAIIMSFLLAFVGLQASGETDINPTGAIAKVTQLVFSRIPSDSLVVVQKTNLMCANIAASVCSQAVDMVGDLKTGHLVGASPRAMLGAQLVGSVFAIGISIPLFILYTKAYPCVLDPTIANCPFAVPAVVAWENVCKILTGDGSIARASMILAFICCALGIINVVIRVKVIPQSWKPYWINLNAVGLGAGLIAGVGIAGLINASMTIAGVKDGPVKAGCGDGGILC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3B7</accession>
    <name>A0A9P6T3B7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001835</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000143">
        <property type="protein sequence ID" value="KAG0021717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3B7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="496"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="94"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="496"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0021717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="566" mass="63769" checksum="8C2CE8515C4927D6" modified="2023-09-13" version="1">MQAKVIGFMSKMQRFKYSAVRILHQEHSNAVLDMAHRGSTFYDPSQVQSRSSYWLAQASCLVAIITEGTKFEPEFENAPVIQGACTNPIHKSDSVLPSTSSSPEDSTERSPYTQSPVSETSAVSNITSTVATSDVPTTPPLLPSPISNGYPSSKPNPRWDDLEPLPMDRFNSIVDLIFDPNIVNISHRRAIINCARYVSASIDESFQKSVSTQEPVNLEFFADFQTRYTIETGPYLTMLTPIRRVDDGSELLPKEQAFAGDIISKAIPPPKRLLNYFQALLWYRCMSDLIHLYNRIRSRHVDVSPRRREPQSLDKTTHASDIYPFCCKAHSLVFTTQYPINIVPYPIRAGFRRVVRIVQSISQKSILSGTVIGQSGSTRAVGRRIQSVGSSKRLNFCNGSAQPPAQTLLNHKRSTPIDDELVQRRYQIEEQTRQDNQVKQELLGLCHMACGLFLIDLQSSDGPSTIMSLLRQGTPWNKGIWREGEWQHDFINQQHYAHQGSDSGPQEGSRFQSNNDPRDMGRWQKLCIAAIQFLAHEDLAWGGNRANAELSRLRATSNANAWVYYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3C5</accession>
    <name>A0A9P6T3C5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">High-affinity Zn(2+) transporter zrt1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ZRT1_1</name>
        <name evidence="7" type="ORF">BGZ80_001740</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000140">
        <property type="protein sequence ID" value="KAG0021781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3C5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005385">
        <property type="term" value="F:zinc ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040:SF44">
        <property type="entry name" value="PROTEIN ZNTC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040">
        <property type="entry name" value="ZINC/IRON TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="16"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="130"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="187"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0021781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="233" mass="25055" checksum="84EC40E5D5FF5839" modified="2023-09-13" version="1">MHPCLFKAWTDDYPSYAPLIMMVSGLSMLVIEFMASTLVLNVDAQRKAAAAAAAVGSASPMEAHDHENHAVWGSTNEKFTNATHSVHVKSSPPSPTTDSRALSRDDDCNHAHCPTLLQCSPGVSTKVSTYMLEFGIALRSVFIGIAVGVLAGHEFLAMTIAICLHQFLEGIALGFRIADLTFSKRWVPFLLVLAFALVTPLGVAIGMGIQSGYKSSNVENFIVITASCCLRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3G7</accession>
    <name>A0A9P6T3G7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003277</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000186">
        <property type="protein sequence ID" value="KAG0020967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3G7"/>
    <dbReference type="OrthoDB" id="120976at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="378"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="444"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="391"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="477"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0020967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="585" mass="65369" checksum="043F6C640E0F2F5B" modified="2023-09-13" version="1">MSGLSALSRLRILNLSQLKIGDIGLSHLIRSVTYGSSGPTMLEYLNLSGTQVTDVGLAKIFDNKSQKQLVFGRLLGIDLTDSKVHEEVAEELFRNHAVPWKRLDNRMSLFPDLPSSKAAKDGYSDLYVESGSGSNPMQKWIDCFSERSFKIKFGQRPDLSLTGKDAWGLLECLALEKLGQIYFHPVSEPTSNYQQELSMNLSTAVGRKSRSKRSRYVRDFDDMLLKAAMINEAQLRQQQSDLEHMYNLKMYQSVLSSIRETAGSLMLSKSRKTKELGATKNLAFVRSRTDVKDLLAGLDLCNDSIGSLLDTHEEMIKVTSVTNNIDNTLKAKVRDRRLRVAASIISTEHIPSQTPMDKSDQRSVPLFDPFPKRLKASISSPFIKREPPTPSSANPSSGSSRDLENRRIFGAHSKYRPPPFVKPAAEQITSSIFVTKVEVNDETTSTPVKLQSPILHANKKSRPSSATMMERWVSKAKQPSSDPTSTSSNKTSVLQNKGQSIDFSSTSGCESIVREFHFTDESGDTVSLDRWIRSEPVVRGLKSGNNMNDFGRSYGDGHSRNVIRFDPKNELFADRDTDVDHQQND</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T4B2</accession>
    <name>A0A9P6T4B2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">L-lactate dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_005874</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the LDH/MDH superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000029">
        <property type="protein sequence ID" value="KAG0024109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T4B2"/>
    <dbReference type="OrthoDB" id="6270329at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004459">
        <property type="term" value="F:L-lactate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006089">
        <property type="term" value="P:lactate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.110.10">
        <property type="entry name" value="Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001557">
        <property type="entry name" value="L-lactate/malate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022383">
        <property type="entry name" value="Lactate/malate_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001236">
        <property type="entry name" value="Lactate/malate_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015955">
        <property type="entry name" value="Lactate_DH/Glyco_Ohase_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43128">
        <property type="entry name" value="L-2-HYDROXYCARBOXYLATE DEHYDROGENASE (NAD(P)(+))"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43128:SF16">
        <property type="entry name" value="L-LACTATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02866">
        <property type="entry name" value="Ldh_1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00056">
        <property type="entry name" value="Ldh_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000102">
        <property type="entry name" value="Lac_mal_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00086">
        <property type="entry name" value="LLDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56327">
        <property type="entry name" value="LDH C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 4" id="KW-0520">NAD</keyword>
    <keyword evidence="1 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="domain" description="Lactate/malate dehydrogenase N-terminal" evidence="7">
        <location>
            <begin position="11"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="Lactate/malate dehydrogenase C-terminal" evidence="8">
        <location>
            <begin position="149"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="179"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="15"/>
            <end position="20"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="122"/>
            <end position="124"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0024109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="308" mass="32958" checksum="58086E3D2DD84EED" modified="2023-09-13" version="1">MSGAKQRGSQMAIIGAGSVGSAIAFACLMRSVVSELLVNDFNEKVCQGQVLDLQDAAFVSSTKVRIGTPKECGQADIIVITAGARQRPGETRDALVLRNEEILRSVLSGLQPIKSTAILMLVANPVNILTCMAQKFSGLPPHQVIGTGTYLDSNRLRVAMRDHLDVAESAVNAYIVGDHGDKQVAVWSSATVGGKPMLSFEEMKNLDLDKEAEKVARKAYSIIDLKGATSFGIAAVVSDLALSIILNKLSVNPLSTYCERFDACLSFPVSLGANGVERIIYPDMNDKEIAMVEASAKFAREACAKYIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T546</accession>
    <name>A0A9P6T546_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_006089</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000030">
        <property type="protein sequence ID" value="KAG0024080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T546"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0024080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="87" mass="9090" checksum="67FF0055427A7B18" modified="2023-09-13" version="1">MSELPILAVVEFLTFVDPLGRPLRPLLATAEAAVDDSPGTNTKVLALTFAAAAAASSPRGKAWVRTQKVGAEGELVPCLKDGIELMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T5J6</accession>
    <name>A0A9P6T5J6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Vacuolar import and degradation protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_002433</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GID4/VID24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000016">
        <property type="protein sequence ID" value="KAG0024482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T5J6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034657">
        <property type="term" value="C:GID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045721">
        <property type="term" value="P:negative regulation of gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007039">
        <property type="term" value="P:protein catabolic process in the vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018618">
        <property type="entry name" value="GID4/10-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14534:SF3">
        <property type="entry name" value="GID COMPLEX SUBUNIT 4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14534">
        <property type="entry name" value="VACUOLAR IMPORT AND DEGRADATION PROTEIN 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09783">
        <property type="entry name" value="Vac_ImportDeg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="104"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="196"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="264"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="346"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="422"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="104"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="203"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="284"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="346"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="361"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="426"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="474"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="485"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00061469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0024482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="774" mass="85098" checksum="25642F93337B1634" modified="2023-09-13" version="1">MSLRPRPDSDNVGNGAVLPITLTNRRQQSHTLHQQPQLSQQRLHSIIHSTAQDTSDADASSDFSSLSEVDLHRDVHSEDFSDYETPFGGRWDLTAHWHLGDYSEGVEGDADDDDDEERDNDTDLSEGPRLGRTINLDLGRVREILGSSPSSTPIIIPSLSTMTTGTATTAAAAAEGREFSLILPLRSVDPDLHSSASEEFEVSHTQGRQPTVATASPERTVRFSRDPQRIHTPIIPSEMSLRTNHLNSMLSEHHALEGYDVHPDMYHADMDDSQGDGGTRRESQSSTNSVNGNSTRDQSASGSSTGDIGNRLNRTALGSIGTGRGEHLTLSVVYDIDAFLRLDSTRASSSTSSPSSVMASDQSNLRAGSQRIHTLQHPPSPSLGREERRYQFRNAIAIASRQNLSSTSRSYISPYWSAHSRYQQHPFSPSPLSSLSPSPVSSASSSRITSPAPESSSLSSNKPSDADDVYGSNLDMNQQQGQNPENEKGDPTLRNEPHSDRDGASKGILSPLATSADSSRFRRVISSNISSLPSFASSVFMPKIQGSGCYGYGGGDGTFSTLGRPLKPNHPRRQCCFLQPGQKFSGTQNLKAHLGSLSGLRSRQREEWRVKVTISAVDYDAGAVYGLMEAIGVPNSSSNVVTFWEGEIIDFENHTFWTKKWTAKAETDVEHWRRMEAFQGIDKKYIVKGAKTGKFRGHIDQKYIFMRWKEKHFVNTTEHSSGLTIAGFYYVSLRRSDGYVEGYYHDQESTPFQHLTLNPVFDAGGFSSSIFQIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MCK2</accession>
    <name>A0A9P6MCK2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_008879</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004985">
        <property type="protein sequence ID" value="KAF9991795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MCK2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9991795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="93" mass="10693" checksum="4F7BDA6F43C68C9C" modified="2023-09-13" version="1" fragment="single">VCDEADGSRVKYAEYGPKAHDREEYQEAIDQYRNLGICKVTTGENTMVRFNIYEVDYDIEPSNSKHANITSYPKDLINTIEVINQFNTIPVTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MD06</accession>
    <name>A0A9P6MD06_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008537</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004656">
        <property type="protein sequence ID" value="KAF9992475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MD06"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9992475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="89" mass="8621" checksum="AF6F7BB1EA94C65F" modified="2023-09-13" version="1" fragment="single">KPDKNGLGAGVGEMVAAIPLANAAAVEGFAVGDIMASAIVTHPTIAAGSGSSAPEGFILGIVAPGTSSDGSRLNGDSAEQESADENDRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MD32</accession>
    <name>A0A9P6MD32_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Origin recognition complex subunit 4 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008406</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004541">
        <property type="protein sequence ID" value="KAF9992799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MD32"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032705">
        <property type="entry name" value="ORC4_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14629">
        <property type="entry name" value="ORC4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Origin recognition complex subunit 4 C-terminal" evidence="1">
        <location>
            <begin position="7"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9992799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="75" mass="8804" checksum="BD1859617AAD58E4" modified="2023-09-13" version="1" fragment="single">SYHDYVEICENALSLSPADLDIEIEEMGPDVDVKEKFIKEFNHRVKMLFDDGGFAKIVQRIFDLMKDVRGFYRLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MDR4</accession>
    <name>A0A9P6MDR4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008182</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004369">
        <property type="protein sequence ID" value="KAF9993314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MDR4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="207"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="218"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9993314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="237" mass="24800" checksum="B75C63D819814AD0" modified="2023-09-13" version="1" fragment="single">RPSPDGIFRPTPPPKSSPGSTPSSSFKKSDVPAPGTVRANSAKFNSMAAEAGNDNSVAASPRSISPKVVSSTASPTSATSAVSTNPWAIRKAVDQPQINSPSKLSSPAASTTSLSDTSAEPSRRNSTPVTLPAPEAYANKELPPIKPELDSGRPITPPKTQENVHQFIEVNEINGQYDMDHASKCIVTEVDTARAIPLADDTSKEILMEQEKPVTDITSTTSATSSGNSTPPKKPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MDU1</accession>
    <name>A0A9P6MDU1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007997</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004204">
        <property type="protein sequence ID" value="KAF9993905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MDU1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9993905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="95" mass="10501" checksum="BEFA8998ED6943F1" modified="2023-09-13" version="1" fragment="single">MVVEREVELTAWVMISRIFTCCLPSGLLRACNSKKFSRAQVVQAWREKVTLCLIISLICGALAFIMFGLTPVMCPDPEGSPTSYTITMPDGTVQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MEY6</accession>
    <name>A0A9P6MEY6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007404</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003787">
        <property type="protein sequence ID" value="KAF9995833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MEY6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05729">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NACHT" evidence="1">
        <location>
            <begin position="72"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9995833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="377" mass="44029" checksum="C3E399473C2EAB42" modified="2023-09-13" version="1" fragment="single">MVTPPPKESPLLDYVQNKPDVETPLRKLRRERLKGRGGDVYISPRAKATPRATDDFDLTAKVQEFLASDKKVFLVLGDSGAGKSTFNRALEVNLWDNYDKINGRIPLFIHLPAIEKPERDLIAERLRKVNFNENQIMELKLHREFILICDGYDESQQTQNLYMSNDLNQPGQWRAQMIISCRTEYSGVEYKDRFQPTDRNNGGSTGQFQEATISPFNKEQTQDYIRQYESLARSSWGSEDYLRALEQIPNLQDLVKNPFLLKISLEVLPRLLKTNTDFSSTRITRVQLYDEFVAQWIDRGKIRLNEMELSPYDKRTLKRMTDSGFQQHGITYLKELVKAIYEHQNGNPVIHYSEHDDRRTWKEAFFSDRDGSHLLRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MF92</accession>
    <name>A0A9P6MF92_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidase S9A N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007412</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003791">
        <property type="protein sequence ID" value="KAF9995806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MF92"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070012">
        <property type="term" value="F:oligopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.120">
        <property type="entry name" value="Prolyl oligopeptidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023302">
        <property type="entry name" value="Pept_S9A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051167">
        <property type="entry name" value="Prolyl_oligopep/macrocyclase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42881">
        <property type="entry name" value="PROLYL ENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42881:SF2">
        <property type="entry name" value="PROLYL ENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02897">
        <property type="entry name" value="Peptidase_S9_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50993">
        <property type="entry name" value="Peptidase/esterase 'gauge' domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase S9A N-terminal" evidence="1">
        <location>
            <begin position="21"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9995806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="321" mass="36802" checksum="15F888AFF85EAD89" modified="2023-09-13" version="1" fragment="single">MTIADAPHTTSLDGKIVYPHVRRTDFTYEQHGVTVADPYRWLEDPHGEETEAFVEAQNKLSAEYMDKFEGKKKYNERLTELFNFERFSSPYKRGDYYYYSRNSGLQAQSVLYQQDTLESEPRVFLDPNTLEADGTAALSSNAFSKSGLLFGYAISKSGSDWNTIYVMDNKGNKLDDVVEWAKFTSIDFTHDDKGFYYSSYEKPDVDTDKAGTETDVNINKRLFYHTIGTPQSEDTLVYLDIENPLHSPNAEISDDGKYILMTISRNCENANMLYIGNLEETGSIVPRDYHLTNDGTVFYFITNKDAPREKVIKYDLAKPEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MGT0</accession>
    <name>A0A9P6MGT0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Reverse transcriptase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003269">
        <property type="protein sequence ID" value="KAF9999257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MGT0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9999257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="131" mass="15107" checksum="50BC14328F96CEDB" modified="2023-09-13" version="1" fragment="single">MYGNIDIDEAIDTINCYFDGQPEEIEVFNLLRLARWVNYNCIVSDGRNTYRQVKGLAMGTPMAPTIARLFACCVEEGYLFKSDPISHVFLDTDEDYFEELDSLTGVVFDLQIYRYIDDGFAIFKIPRYQGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MGX1</accession>
    <name>A0A9P6MGX1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006499</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003204">
        <property type="protein sequence ID" value="KAF9999829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MGX1"/>
    <dbReference type="OrthoDB" id="2441427at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="344"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="136"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9999829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="368" mass="41492" checksum="653F0278BD011344" modified="2023-09-13" version="1">MASNKNNNANVQESDSSEVHPANNHNNNEGRPIFSLTMDPNVFEQEVDQAARALQHTMNSLFNSMQSSVFGGFESLQKEMSAFERSSKEFMEQHPFHSYHHHFPWSFRTDGPKKRYRITIEELPPLEDEKSSRLISTTTGSSSSSPSPSTSTKDANDEEETTITQGKVGTPDEGKTVITTSMPPGLLDWLLFTTHDDSFFRRLGRPNNNNVETSTTDLSGAKITELSEAEPSKEEQEAARQRMVPGLVEKVKEVGSTWERGARHLWQRYRGGEQGDLKEIEREEQDSRGWPRGRSWGFNESFSQTTVTRPDGTIEHRSVCTIDGETETVVKIQHPDGTVEETVNIENNGGHGNRHGRWAYHGDKDRKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MI24</accession>
    <name>A0A9P6MI24_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cyclin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_006369</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the cyclin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003141">
        <property type="protein sequence ID" value="KAG0000422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MI24"/>
    <dbReference type="OrthoDB" id="5590282at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044772">
        <property type="term" value="P:mitotic cell cycle phase transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20512">
        <property type="entry name" value="CYCLIN_CLBs_yeast_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000001">
        <property type="entry name" value="G2/mitotic-specific cyclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039361">
        <property type="entry name" value="Cyclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046965">
        <property type="entry name" value="Cyclin_A/B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004367">
        <property type="entry name" value="Cyclin_C-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048258">
        <property type="entry name" value="Cyclins_cyclin-box"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10177">
        <property type="entry name" value="CYCLINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02984">
        <property type="entry name" value="Cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001771">
        <property type="entry name" value="Cyclin_A_B_D_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01332">
        <property type="entry name" value="Cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00292">
        <property type="entry name" value="CYCLINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="2 4" id="KW-0195">Cyclin</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-like" evidence="6">
        <location>
            <begin position="118"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin C-terminal" evidence="7">
        <location>
            <begin position="211"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin-like" evidence="6">
        <location>
            <begin position="215"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0000422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="344" mass="39689" checksum="F3091CFA17F9F884" modified="2023-09-13" version="1">MARSSVQTIQRPNIPKEPSRERHCPLIPAVPSFDTPNSEHNMEGLTHTVDDPHTYMPDMDLDVIPGEDEYDHDPTLVSEYQQSIFAYKREMEIKLMPDPNYMSKQSDLTWRYRVLIIDWLVQAHDQFDLLQETMHLCVNYLDRFLSKVIIPVNQLQLVAIVALLLASKYEEIQAPAIEALVHICNNVYTRTRVREAEIGMLRALNYDMGAPGPMSFLRRISRADNYDVDIRTLAKYLIDVTLCDHRFIGHPSSMIAAVGYHTSMRLLFRGGWTSEHECYSGYTELMLIGGVNVLLTMLEHPDQSHQAMFKKYQDERHMKASDYVQQLGLPLLQSLQYKPTSDTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MKG6</accession>
    <name>A0A9P6MKG6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_005231</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002596">
        <property type="protein sequence ID" value="KAG0006535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MKG6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="84"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="155"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="249"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="442"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="615"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="839"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="972"/>
            <end position="997"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1025"/>
            <end position="1097"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="754"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="25"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="168"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="259"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="856"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="972"/>
            <end position="985"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1026"/>
            <end position="1041"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1045"/>
            <end position="1062"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1063"/>
            <end position="1082"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1083"/>
            <end position="1097"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0006535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1172" mass="130045" checksum="7F4B897FFDCD2E69" modified="2023-09-13" version="1" fragment="single">MASTDYQHLEQQSLDTHVTPEQDRPLPLLPSNSDPSRNLENPINSLQTTRTIVSNVDHPLQPNQNIQTVDTLAAVQFPSANSNLNQTQEHHAHAHTQGEDQSLLRTNSPEPILSSIESHDPSIPEHIYVHDNVDINNIDQETYIDRGTNYDTPLVRDLNSGGRGGETVPTSEDSTLPRTYSPLIQNGIATEQPCPADTRIALSQVLTSFHDAGFNTLYVCPPISTSIEDRRTGPYDQIEDAGDITIPTTNSSVHSSSSTQPPIVPSTTQDDPTLTISEFVALPRALPRRRYTTRDYSSGSVSSDDWLRHPDVVAFPMQDNPDPTLENQENIPPQSLAHVEGVTSESLRGIDNAFTPTSASAMHAAGTPYTPFEDRAQTQPVEQDTQDVLRHHDLQEDHQVARMIEDLTISGSTLPIVDPTVNNAIAAPIVSDDDRTLPLQDAQSVDETEPVSAPASDPPTEASHPDRLGLLGPLLSRTQPASATSSEDRLEFSLLGSTRPGFDSSILSMASRIRQARLMRLLRRMREREALGGYAERYPWADTRSMVNHASGSRGTSRAGSLEDGFLDLGPDMSAHDAIAESSWNSIHHHDQSAPHLNPSPFYTIPPPSFTEILDCNGNPIEWGSDSSSNTSHEAVEERNSEQDWAQNAEMWRQRRAWMERTGWDRGIIRTHGRTRIISTGTAFEGMEFISEADSLLLGNHRNQSLKSSWVTNPNDSQYQPGTVNGTGLYQLYSNVRNHYGPENARRRRVMSEMTDLLWREQEWERELERYERELSAFRSGLFSRMASQPTDNSALSITTLSPYPRMTTVGASTEAASTSSNPEVSSLVDLQQRDIAGSSSQSDIIFGRQGERNSPLWQRSDANGQSDGIVNEPAQGFHEYEQGNSHYHTQSISSRAQQQEPIFNQPTQHQYQSMPRQPTVAMMNRTPPPLPAQPQINEPIAHQIRRVHTPHMLTLQRRWEMQQLLVHQNQTPQYRQVQRQQQHQSPGGPVIGSLENMSHQRNPNAVFIPPPAQQELHNNSFATASASSVPLSRGSRSSLRTSHESNSFQHFRLSGNSIPPRSQSAASFSLSSVVPLAPPDSQEATTSNVTTDTDSGAGNAMNSILTLESLPTSFSTSSADLPASISSSSSESQNHSDYRNQFYWRTRISGSNSLYVNYEGGKLKPEERWRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MLH0</accession>
    <name>A0A9P6MLH0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Alpha-(1,6)-fucosyltransferase N- and catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005125</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002545">
        <property type="protein sequence ID" value="KAG0006820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MLH0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046921">
        <property type="term" value="F:alpha-(1-&gt;6)-fucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045573">
        <property type="entry name" value="Fut8_N_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13132">
        <property type="entry name" value="ALPHA- 1,6 -FUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13132:SF29">
        <property type="entry name" value="ALPHA-(1,6)-FUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19745">
        <property type="entry name" value="FUT8_N_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha-(1,6)-fucosyltransferase N- and catalytic" evidence="1">
        <location>
            <begin position="143"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF19745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0006820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="315" mass="36704" checksum="C38F5B0C2D1482E8" modified="2023-09-13" version="1">MGGRGYELLTSFADDERLGLHKELDRLQHRCDNFFNGAFHPFGFGANWHNLGLGLAHSLYYNMTLYPHDEYKYFIRMTTCTEEDLKRSFGAHPPETNFTRWNISTINFKSMGNIATINVESMGSDEGDLLKRKTIIRSEYQDKGHFWWRSMLTYYLMRPNIGLRELIRQSSTVTTPCMSIHVRHSDKSSEAALIEFSKYMEHAERYRAKTQVSSVYLLTDDDEVIKSTKNYSDFQFHFLDMARSNKGWEADRDTGMSRDQQERTFLIDIFSAVRCQHSIVTYSSNVGRLIAEVAYAIRNREPNVVSLDEAWKMDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNK1</accession>
    <name>A0A9P6MNK1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase M20 dimerisation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_003807</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M20A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002025">
        <property type="protein sequence ID" value="KAG0008144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNK1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016805">
        <property type="term" value="F:dipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05672">
        <property type="entry name" value="M20_ACY1L2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.360:FF:000004">
        <property type="entry name" value="Peptidase M20 domain-containing protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017439">
        <property type="entry name" value="Amidohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052030">
        <property type="entry name" value="Peptidase_M20/M20A_hydrolases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01891">
        <property type="entry name" value="amidohydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30575">
        <property type="entry name" value="PEPTIDASE M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30575:SF0">
        <property type="entry name" value="XAA-ARG DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="Bacterial exopeptidase dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M20 dimerisation" evidence="2">
        <location>
            <begin position="208"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0008144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="435" mass="46931" checksum="9EF95E14FAA2F030" modified="2023-09-13" version="1">MSSEKSPSSSEEQPQVAPSTGCLAIFKGIFGNASNGSTSQSKEQTYSEKNAQAYREMISTSSSSLPPAYEALQQEMSQLRVNGSSDIKLSDLWENNEFAKTVHHAIEAVSAELREISLKYDALPGIGHACGHNLIAISGVATAIGIKAVIEKFHLAAQVKLLGTPAEELEGGKIVMLNKGAFENLDVCMMLHGANTDVIYTNFLALDTVEVEFFGKASHASASPWEGINALDAAVLTYTNIGLMRQQMRPDQRVHGIIKDGGKAANIIPDYTKSVYTVRSPKYSEVEVLKKRVEAIFKGAAAATGCRVALKWGSPYMDILTNDPLARKFEHFMNAQGLKYAPKQEQQSKVSGSTDMGNVTYALPGIHPMFNILNLEGKDDNSMGLHTSAFASAASQPTGHIATLRAAKGLAMTGVECILDDEFLDSVKKDFESTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNL0</accession>
    <name>A0A9P6MNL0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">GPI inositol-deacylase</fullName>
            <ecNumber evidence="10">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">BST1_1</name>
        <name evidence="14" type="ORF">BGZ80_003633</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the GPI inositol-deacylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="10"/>
    <dbReference type="EMBL" id="JAAAID010001977">
        <property type="protein sequence ID" value="KAG0008264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNL0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050185">
        <property type="term" value="F:phosphatidylinositol deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006505">
        <property type="term" value="P:GPI anchor metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012908">
        <property type="entry name" value="PGAP1-ab_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039529">
        <property type="entry name" value="PGAP1/BST1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056824">
        <property type="entry name" value="PGAP1_TMD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15495:SF7">
        <property type="entry name" value="GPI INOSITOL-DEACYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15495">
        <property type="entry name" value="NEGATIVE REGULATOR OF VESICLE FORMATION-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07819">
        <property type="entry name" value="PGAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25141">
        <property type="entry name" value="PGAP1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25140">
        <property type="entry name" value="PGAP1_TMD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="926"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="967"/>
            <end position="988"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1063"/>
            <end position="1086"/>
        </location>
    </feature>
    <feature type="domain" description="GPI inositol-deacylase PGAP1-like alpha/beta" evidence="12">
        <location>
            <begin position="340"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="domain" description="GPI inositol-deacylase transmembrane" evidence="13">
        <location>
            <begin position="1050"/>
            <end position="1094"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="39"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="103"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="121"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="154"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="189"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="204"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF07819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF25140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0008264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1120" mass="124636" checksum="B4B9D4872BF994FD" modified="2023-09-13" version="1">MQSTFINISDLNEHVHVDDNDSIRPYHLLLSMNHDDDIHLPNGDQSDQHRLNGRIHPSQPKSDLVLDDLDLQQQQQQGEALSHTKTSQSVRNHHCKDHPPNTEPNGSSQTNQPRRSERLRNSNGYSKQQGSSNQYQHHERKPSLPTKRLSASIQSNGSSPTSNTSTPTSPSQYSLPYSHSHSSRSMGSTDKEQGDGKPGKHDYTSASASASGPASGRSRTRSKSHPELPNIPLMKACQSSSFGCSYSMAIVLFASLSLLGCIFHSNFYHQVDPNICQYTYMQPRYFRLLGFDRERTAFAGKYGLLLFRDQTDYKLQLPASMLSEYSNSVYAVDKEAKIQPMGIPALFIPGNAGSAKQMRSIAKEASKYYYENLVDAQRNVKSTSRPIDFFTVDFNEEFSALHGHSLLEQAHFLNDAIAYILSLYDDSRNLDPSLPKPTSVLIVGHSMGGIVARTLFTMSNYKPGSVKAILTAATPHLVPPVTLDFEISNIYDRIESFWSRGFQGPDAPLNNVSLVSVAGGNLDIIVNGESGNIHNIVPQSHGFTVFTSSIPHAWVGSDHVAILWCNQIAIALGKTLIDIVDSSYPEQVKPLEERMRIFRNRLLTGVEDHLEHVSNSKVEEIIDVSETDHTFINSESVLAYPFKNRAATQDESDRPHLYITPLPQNRSIDTLNILTDHLLGQESRLDVLVCKDVSSDTNAPTSPSSSSPVPNQLSCLHNALTVIPVPASPINSPSPTHTTRYNRGQEFRFVTQKLEELNDAQYIVILDRGRSISEPGFLIAEFAAEAETIVTSETTTRGLLNNGFRVHGFPERPSLVSTLRLPNIDNSLLTYTLTVDRPGCHVPVRFSPMMRQSSWAMNEDRYSVDVTSKKNGLDINFHGDIPYFERVQLPGRKGIEFRFWMDPTCPVPLSINLQVDRYGSMGKVVIRYRMVVLVFTFLAVVLTLRAQFKAFNKGQPFIPFGVMLTQLIKTTFWKFSILLAVIAFVQSLQAKTSVIFESPTTSGVTSLHHGGNAADEIIQGSAGTRTTSWNAYDEMIQKRIARSESWFSSFRFGDALLGSNDTFFWFLAPLFFQISVGIVILIWLALNGLVRATAIGLTFVAKRGGRYVLGKAIGNILSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPB7</accession>
    <name>A0A9P6MPB7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="14">NADH-cytochrome b5 reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">CBR1_2</name>
        <name evidence="14" type="ORF">BGZ80_003069</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001792">
        <property type="protein sequence ID" value="KAG0008773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPB7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06183">
        <property type="entry name" value="cyt_b5_reduct_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.80:FF:000019">
        <property type="entry name" value="NADH-cytochrome b5 reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001834">
        <property type="entry name" value="CBR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370:SF184">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00406">
        <property type="entry name" value="CYTB5RDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0274">FAD</keyword>
    <keyword evidence="4 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="13">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="11"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="11"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR601834-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0008773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="201" mass="21872" checksum="329B5F606E926A84" modified="2023-09-13" version="1">MAHINGKDISRSYTPTSSSDDVGHFVLCIKSYPQGNISKMFAELKIGDTINARGPKGQFNYTPNMCRAIGMIAGGTGLTPMLQIIRAILKNPEDKTLINFIFANVTAEDIILKAELDALAAKHPQFKVYYVLNTPPEGWTGGVGFVNAEMVKEHMPAPAADIKVLLCGPPPMITAMSKITQDLGYDKVNAVSKLPDQVFKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPE5</accession>
    <name>A0A9P6MPE5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nadh-ubiquinone oxidoreductase kDa subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_002456</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001607">
        <property type="protein sequence ID" value="KAG0009375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPE5"/>
    <dbReference type="OrthoDB" id="2093493at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22849">
        <property type="entry name" value="NuzM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016813">
        <property type="entry name" value="NADH_Ub_cplx-1_21kDa"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37325">
        <property type="entry name" value="OXIDOREDUCTASE 21 KDA SUBUNIT, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G05910)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37325:SF1">
        <property type="entry name" value="OXIDOREDUCTASE 21 KDA SUBUNIT, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G05910)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0009375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="159" mass="17497" checksum="BB8A596F84E83F6F" modified="2023-09-13" version="1">MAKSAFWNSVRKALTVNPKVSTGMPDAKEFRFVAPGGQPKTHVPHDPLAHDIAQNPYYGRDFRRNYPRLAVYSQEEVAGLIAAKEALAIGSGESAVANAGENLSLTEVIKNAKAPLFTPNNLPPTPLVPNRNFKWVLSPDQPPVDEGTYWTMRNMKIAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPG0</accession>
    <name>A0A9P6MPG0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_003068</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001791">
        <property type="protein sequence ID" value="KAG0008777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPG0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040370865" evidence="3">
        <location>
            <begin position="20"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="680"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="233"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="399"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="190"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="299"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="338"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="416"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="527"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0008777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="704" mass="76448" checksum="A7AF4BA7D4213F81" modified="2023-09-13" version="1" fragment="single">VGLCGQFLMAMVIPFLSTSLLCPPYASQISGTRLLDTFDPKTGYYELCYKTAPGWTEVRVGRKVYKDGYDFFIKPDDPTVRVELAPDFGGVRIWTTLDHEGQSITAQVSRKGQNAIRPAQQKFLQLQQEDDGDDIDRSGRRSRDSFVPQRPRDSRVFESTSPTYGGPSPRKSASHLKSNEQSDNDEQIESGSAVDVGSGSDLRPQRTQTSVSRKRRSASFTTLSSFDPNLVVASSSDRRAEPLQTSMMPKASEESERSRSRSRTPRSLAKVPILGAPPPPPPRRSSSLGRHSIPAITLFQGNSRSVPTKSSITSPTFGARPALIPPTDSIVPLPPPSISTNVSSPATLNGPLSSPTLGPFHNPQLPEPVTSLNGDLLFSDTPLSKDAILQPAAEIPSCPVTSSPLADSLAPFSTGAAFSSSPDIVSVSLDGSESRGSSDLSLAESESEPESSKGSESTEMSVRDSIEENVMSLAIMDSPQSPPRPRAASALARRKDSGSRRVTFSPDVVDNPENRPPLQRPRKSSLRKSSSSASVDPPSEPQDLKVDGIKWEGKNLEIKEVAGSKVVIVDEVVGEVAMVNVAIVEDGNEYESDEAEFVEASTELSDADPEGQTEEKEKEVVVVEEEKKEKEVVVVAAEETTVVEKKKVLMEMEYFQENEAMWQMAVESFIEELRSMQTRLAVVFVLLMVIASGLSTPFVLRFLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPL0</accession>
    <name>A0A9P6MPL0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_003349</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001880">
        <property type="protein sequence ID" value="KAG0008524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPL0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0008524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="81" mass="8885" checksum="D4A57810EF78F94A" modified="2023-09-13" version="1" fragment="single">PILGDAKYSLEETRKGGEPGRLYLHMAELTLKGWLQDGSKAILKGESSSGYTVLEDGSLVVRAAMPKDMQRQIDQLGLKTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPR6</accession>
    <name>A0A9P6MPR6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Integrin subunit alpha 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ITGA8</name>
        <name evidence="8" type="ORF">BGZ80_002260</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001552">
        <property type="protein sequence ID" value="KAG0009572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPR6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031012">
        <property type="term" value="C:extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004621">
        <property type="term" value="F:glycosylphosphatidylinositol phospholipase D activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007229">
        <property type="term" value="P:integrin-mediated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.130">
        <property type="entry name" value="Integrin alpha, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013517">
        <property type="entry name" value="FG-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013519">
        <property type="entry name" value="Int_alpha_beta-p"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23221">
        <property type="entry name" value="GLYCOSYLPHOSPHATIDYLINOSITOL PHOSPHOLIPASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23221:SF7">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN-SPECIFIC PHOSPHOLIPASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01839">
        <property type="entry name" value="FG-GAP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00191">
        <property type="entry name" value="Int_alpha"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="Integrin alpha N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51470">
        <property type="entry name" value="FG_GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0401">Integrin</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040412226" evidence="7">
        <location>
            <begin position="19"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="repeat" description="FG-GAP" evidence="5">
        <location>
            <begin position="388"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="234"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="506"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="810"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="249"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="517"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="817"/>
            <end position="830"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0009572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="908" mass="100883" checksum="2F97CC777484E88C" modified="2023-09-13" version="1">MSWHALWGLNSGFIRAVANTSFAGDYSKGHTLADIGAEFVLSHMTKMDHLVTSWRVPVKDISQIYKRMGYTVPGPVLSHCMRNGYAGAQANARLGSQLFPVYASKSPFLAEQVEDYPMGGLRDMSEWTVDCWNGLAEYLNKERKLPDDEDRRANRTINLCYALWEERIMKHHHDAMQRTQDGEVRHQHESNAVSEGAFALTRLDLAGLQVRSDFDDHTGMVTFSIEETELTRSKRVNAETPFTVDDEEDKRQQQSLDDRRNHNHFQDLTGLSLQQKLDWNSHTLEAGLNLKKLAHKNRSGVCISFSDELKSQARTLFLPIEYSSFGHAAVMGDFDGDGNLELAVSAPHMRINPLVPSQGAVFVIHSDSLFVDQNDNDDFGTDVRSIASRTLYGDSSELQSRFGWSLAVVDLNQDGIDDLAIGAPGHGAKDLKYDGSVFVYFGHAGSGLSEEPDLVLYRNRTKDEVDKVPRGMNSLAGLGYVLQGLDVTGSGYKDLVIGMPMATTPIEPVLGETPEGTLEETPEDKSDDVEDLVPKRGKKWKPPKFRAQAGKVLVFLSSAEHKGQKLDTENDWELQGEDEYGWFGSSFAVISQAQQGWKTSTSTWSLSSLLSWMSPSRFRNQCGCCHSKEKVNERRILVVGSPTFGVGEKEAMRGKIQGFVIPDFKSKERPTETQKVFTIHGDTKSQQLGSSLALNRVSPEEFGEPQDFLVVGSQSEDVLNHLPRVGRQWQAGTVRILDTSVLADGAEVKISDLDANLDVVRDILQGSQSMAHLSAAMRVSTDGKSLWLTEPYANAEAGRILEWVPNLEKRDSDGNRGRRTGRSRGRRMSPRRNVLGVRGRRLVHGDYLQDGGDGDEDEDDAAQDDIKQCFIGSDFRGRFGSHLVVADLFKDGLDDIVVTSSHASQYAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPS6</accession>
    <name>A0A9P6MPS6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Nuclear mRNA export, poly(A)+RNA binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">MEX67</name>
        <name evidence="11" type="ORF">BGZ80_002232</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NXF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001546">
        <property type="protein sequence ID" value="KAG0009596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPS6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016973">
        <property type="term" value="P:poly(A)+ mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002075">
        <property type="entry name" value="NTF2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018222">
        <property type="entry name" value="Nuclear_transport_factor_2_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057125">
        <property type="entry name" value="NXF1/2/3/5-like_LRR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030217">
        <property type="entry name" value="NXF_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005637">
        <property type="entry name" value="TAP_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10662">
        <property type="entry name" value="NUCLEAR RNA EXPORT FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10662:SF22">
        <property type="entry name" value="NUCLEAR RNA EXPORT FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24048">
        <property type="entry name" value="LRR_NXF1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22602">
        <property type="entry name" value="NXF_NTF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03943">
        <property type="entry name" value="TAP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00804">
        <property type="entry name" value="TAP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50177">
        <property type="entry name" value="NTF2_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51281">
        <property type="entry name" value="TAP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="NTF2" evidence="9">
        <location>
            <begin position="419"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="domain" description="TAP-C" evidence="10">
        <location>
            <begin position="649"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="204"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="42"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="104"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0009596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="704" mass="76642" checksum="20953545CF85892C" modified="2023-09-13" version="1">MIPGRGRFGGRGGRNGNNDRDQNDGAATVTGNTEIGFFTNRRGGGGGGGGGGGPVRDSNRRNRRGGVRSSVALPPRPGRGGEDMDGDLSMGGEKKNFSPYQRPGRNTRSTTTTQSDPAGAVVIFVRTQEGQSLTTDSELYDFISRKAQPTKINITKKSSNEMTGAVSFSVDNIAQAKSVRALSGIRYKKQKLIINTTQDEKIFGSSSSTSLEIRPSTSSGSASRGTIESIREFLRSRYNGGFLNLENMSKDEILRNARIFPPGNTKGRSDVGAVMMKAASEMFPETVTISFASNRLTSLQPISSVAQFFPNLQNLSLKDNNIYNYKELEYLSGKKLPNLRELILLDNPIRDKDIQRNNDDLTYRSEITKLFPSISILDQTPVAPKITFGLGDLTKNDLKPALPAPIKGNFFDNPATQATVLEFLTSYLELFDSNRSLLEHAYDNNATFSYVVMPLQSPLQRSRGKPADNWTGYNSQSRNLSRVKDLGQRTTRMYFGSRDIIQQGLMKFPETKHDLTDASKISVDSWQTGGLLPSVCIYIMLHGEFEEVRRGSRDGPKKSFDRSFIIAPAPAGSGAALHGWKCIIISDQLTLRGYNGSAAWKPEEDTTVTPSNAAPAAGSSSAFTPSLSAAVAAVAASVNQQAPMDGVSPEQHAKAQELQKLTGLNYPYALQCLMASGWDIPKGVALVNENRANIPQDAWQQPAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPW2</accession>
    <name>A0A9P6MPW2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Poly(A) RNA polymerase mitochondrial-like central palm domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_002410</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001593">
        <property type="protein sequence ID" value="KAG0009421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPW2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010605">
        <property type="term" value="P:negative regulation of macromolecule metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031123">
        <property type="term" value="P:RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22249">
        <property type="entry name" value="UDM1_RNF168_RNF169-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054708">
        <property type="entry name" value="MTPAP-like_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12271">
        <property type="entry name" value="POLY A POLYMERASE CID PAP -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12271:SF40">
        <property type="entry name" value="POLY(A) RNA POLYMERASE GLD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22600">
        <property type="entry name" value="MTPAP-like_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81631">
        <property type="entry name" value="PAP/OAS1 substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Poly(A) RNA polymerase mitochondrial-like central palm" evidence="1">
        <location>
            <begin position="284"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="643"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF22600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0009421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="643" mass="73719" checksum="B8125556193ECAA2" modified="2023-09-13" version="1" fragment="single">MKINRRHFVGILYDCILFEYGSQVTVGKSHTLSLDDLAETFAFVAAFYKHNRSLMDIPCDQFITRNQLHTVAGLVDYIENMDRGVFEIFPCSIELREEAPSFSSSSSRQDRKRHTRMTLEHGDIKSKSNHSQFRQDVRGWTMDLYGHRGHDFHTDTDTDLDDEYSIIIPGLSKTDVQTFLWEYAYIPEVYQDDIATLIRYLRRDEWMMNGSKGSIITFDWDLEGVQKFSKEYNQNKIRKVELREQEEAKKTQEIAQKQQEEWARQQELIRERETMRRMKIADDFIRKMHKTMVISPSESEEIDKLIKNLETEISEYFDFCFVALVAVGSFACGQYTHTSDLDLTLTGNTKNITTVELVNALHHFSYQNVNIVERNVEPAVLSASRSTRLSVVTFVDPKTGTTCHLTLDEPLLIYQSKLIRTYALIEPRFGPVMNALRHLAAQRGLISSSEHGDKCNFMPLGSYALALMLTTFLQTENPPILPKLQQNPLPEDRVMKEAFVNGIDCSFDRDWEYYQGFGIKNTKSTAELLVDFCRFFGYVFDYESKEVNARIGAFRWRSDVSRGPANTLISSVEADTGRAPPPSPTVPLSPTVASALGSKVNSSVVFQVIDPFLIDFNVTNVCRGELVRIVKSCFQEAYEALVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPW5</accession>
    <name>A0A9P6MPW5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Mitofusin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">FZO1</name>
        <name evidence="16" type="ORF">BGZ80_002104</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001509">
        <property type="protein sequence ID" value="KAG0009746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPW5"/>
    <dbReference type="OrthoDB" id="9984778at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008053">
        <property type="term" value="P:mitochondrial fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051646">
        <property type="term" value="P:mitochondrion localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000638">
        <property type="entry name" value="Transmembrane GTPase Fzo1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030381">
        <property type="entry name" value="G_DYNAMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027094">
        <property type="entry name" value="Mitofusin_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10465:SF0">
        <property type="entry name" value="SARCALUMENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10465">
        <property type="entry name" value="TRANSMEMBRANE GTPASE FZO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51718">
        <property type="entry name" value="G_DYNAMIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8 13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Dynamin-type G" evidence="15">
        <location>
            <begin position="225"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="98"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="774"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0009746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="833" mass="93728" checksum="575ED6626DC8EF19" modified="2023-09-13" version="1">MTSYFSAQNSQSSAASQRRSSLPRLSMDDTERPHQPAHHVLPSLSHTAAATVPRESPYNHNLFLQQQVFADKSNRLLNLIQNTKGLLEEIRETNATKPWQTYYPSPQIPATSATSASSNPLRRSTSFHPEDDTERSSSLPLQQRIQRSFTSAPGSPQNAHTSIELPSTGRLFELNVLKLDLKVGNYATGNDALLRGLERNTIAHLLDGRIQQSVKHLDNLYQRVGDKSSKVLITGDLNAGKSTLVNALMQRTILPVDQQPCTSLFCEVLDAQENEGQEAVHAIKDPSTYNRQDPNTFTVVDMRHLEKFMNDVIDGYEDYAQLKVYCTDRRMVNDSLLHNGVVDIALIDSPGLNRDSVKTTALFARQQEIDVVVFVVSAENHFTLSGKEFLWNAANEKTHIFIVVNRFDSIRDKERCKRVILDQIKQLSAKTYEDADELVHFVSAGSCLPEIIQGGDLPADFLRLEECLRSFVLEKRCKSKLAPAKVYLENILSDVSVLSESNRQMAAEELAKVRLELERGEPEYQDTLVRREMVLEKVDRLSEETCSLIDAMTREKLSNSVDDIENAVSTLVPWNGLLHLWQYSNDLRYVMADLFVDRVKSCETEAKEKTKACVNDIHNLANESLPVVQSDVVALFTKPDPTRISTGKLKDELALDLTDMFDIQDKLGVASVSLGAVTMFSSKALGYKSLIHSLFDITNTVGVSNVRKWAVPVVTVAGLGILVYIAADIKHALARKTARKLRAHIREGTIVHDEAMRITKDCRRVFKGNAWDIQNRFQREIEAHERRRAEQEKAAKDGEQAVIYFSKVFEKADELARWVAAVEVEVEERKLKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQ36</accession>
    <name>A0A9P6MQ36_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Lon protease homolog, mitochondrial</fullName>
            <ecNumber evidence="11">3.4.21.53</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11 17" type="primary">PIM1</name>
        <name evidence="17" type="ORF">BGZ80_002954</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>Hydrolysis of proteins in presence of ATP.</text>
            <dbReference type="EC" id="3.4.21.53"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homohexamer or homoheptamer. Organized in a ring with a central cavity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11 12 13">Belongs to the peptidase S16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.53" evidence="11"/>
    <dbReference type="EMBL" id="JAAAID010001755">
        <property type="protein sequence ID" value="KAG0008884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQ36"/>
    <dbReference type="OrthoDB" id="2411602at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051131">
        <property type="term" value="P:chaperone-mediated protein complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070407">
        <property type="term" value="P:oxidation-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006515">
        <property type="term" value="P:protein quality control for misfolded or incompletely synthesized proteins"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd19500">
        <property type="entry name" value="RecA-like_Lon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000021">
        <property type="entry name" value="Lon protease homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.5270:FF:000001">
        <property type="entry name" value="Lon protease homolog, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.1480:FF:000003">
        <property type="entry name" value="Lon protease homolog, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.130.40:FF:000010">
        <property type="entry name" value="Lon protease homolog, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000015">
        <property type="entry name" value="Lon protease homolog, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.5270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.40">
        <property type="entry name" value="LON domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03120">
        <property type="entry name" value="lonm_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004815">
        <property type="entry name" value="Lon_bac/euk-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054594">
        <property type="entry name" value="Lon_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008269">
        <property type="entry name" value="Lon_proteolytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027065">
        <property type="entry name" value="Lon_Prtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003111">
        <property type="entry name" value="Lon_prtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046336">
        <property type="entry name" value="Lon_prtase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027503">
        <property type="entry name" value="Lonm_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008268">
        <property type="entry name" value="Peptidase_S16_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00763">
        <property type="entry name" value="lon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43718">
        <property type="entry name" value="LON PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43718:SF2">
        <property type="entry name" value="LON PROTEASE HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05362">
        <property type="entry name" value="Lon_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22667">
        <property type="entry name" value="Lon_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02190">
        <property type="entry name" value="LON_substr_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00830">
        <property type="entry name" value="ENDOLAPTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00464">
        <property type="entry name" value="LON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51787">
        <property type="entry name" value="LON_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51786">
        <property type="entry name" value="LON_PROTEOLYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01046">
        <property type="entry name" value="LON_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 11 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 11 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 11 12" id="KW-0645">Protease</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11 12" id="KW-0720">Serine protease</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Lon N-terminal" evidence="16">
        <location>
            <begin position="209"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="domain" description="Lon proteolytic" evidence="15">
        <location>
            <begin position="968"/>
            <end position="1154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="118"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="332"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1162"/>
            <end position="1201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="119"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="147"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="348"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="1169"/>
            <end position="1199"/>
        </location>
    </feature>
    <feature type="active site" evidence="11 12">
        <location>
            <position position="1060"/>
        </location>
    </feature>
    <feature type="active site" evidence="11 12">
        <location>
            <position position="1103"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="665"/>
            <end position="672"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00050665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0008884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1214" mass="132049" checksum="AD6A4D42A5FC393D" modified="2023-09-13" version="1">MAARNAVLVITKRVSPSVDLLKVALSRTTVNPTLTHHATAKTPKTWSAFDGHLRPFSTIPSTSSSASAHPNELRPRSLHSLVQATRPAAIAHGYGHNNYLISGSTLTLSRRSFSSTARILKDKSDSGKGDGGKGDDGKNGSDGKDSGSGSSSSSGSEGGSSNSGSGSSGSGRGGKTSKFTFDVGSGGPSTNILENGLSKPAIPEVYPQVLTLPIGRRPLFPGFYKAVVIKNPAVANAIKELMKRGQPYVGAFLLKDEELDIDTVTSMDQIHPVGVFAQITTVFPASAGSDEGSITAVLYPHRRIRIKELLPPLVLPDGSEAPREGLMIKEAEEGAEKQQPITIKVGEESSVVSSESSSSTTTIEKVAGTESTAAEVTTVDGAPSTSDSDSASKSHHHLPTDFLAKEYAVTLSNVENMIDEPYNRKNQVIRAITSEIVAVFKDIASLNPLFRDQIANFSMSQSAGNVFEEPAKLADFATAVSQGDPEELQSVLESLSIEDRMQKALLVLKKELMNAQLQSKISKDVENKIAKRQREYYLMEQLKGIKKELGIESDGKDKLIEKFKEKSVKLAMPEQVKKVFDEEITKLEHLEPAASEFNVTRNYLDWLTNVPWGVRSPENYDIRHATRVLDEDHYGLKDVKDRILEFIAVGRLRGTVEGKIICLAGPPGVGKTSIGKSIARALDREFYRFSVGGLTDVAEIKGHRRTYVGAMPGKVVQALKRVQTENPLILIDEIDKVGRGHQGDPASALLELLDPEQNGSFLDHYMDVPIDLSKVLFVCTANVLETIPGPLLDRMEVIQLSGYISDEKVAIASRYLAPSAKEAAGLQDANVTLHDDAIEALIKNYCRESGVRNLKKQIDKVFRKAALKIVRDLPDVERVAPKKEEVEDKKADKTEKVNDDPLLDFIKKPVPDETLLDDEGAAKQAEKDSKDQKPILQVPSNVSVDITADNLKDYVGPAVFQADRLYDATPPGVVMGLAWTSMGGSALYIESCLDGGLSEKSRPNFLKTGQMGDVMKESTSIAYTYAKNLIGRRFPENRFFNKAAIHLHVPEGATPKDGPSAGITMTTSLLSLALNKPLDPTIAMTGELTLTGKVLKIGGLKEKTIAAKRSGVKTLIFPQANLPDWEELPENVKEGVTGVPAAWYEDVYKVVFGDSITEEEGNSVWTKELPGDKEDGDDADNREPRRDETHVKKFKKSDDGVLSSGISWREMLRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQK9</accession>
    <name>A0A9P6MQK9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_001886</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001445">
        <property type="protein sequence ID" value="KAG0009979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQK9"/>
    <dbReference type="OrthoDB" id="346907at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="37"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="2">
        <location>
            <begin position="562"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="2">
        <location>
            <begin position="598"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="2">
        <location>
            <begin position="632"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="291"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="411"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="463"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="314"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0009979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="767" mass="84731" checksum="21D6F874EE18A432" modified="2023-09-13" version="1">MTDRTAPVVLFSAKEQQWLDGAINGNLLRLINFDDIEGLQMGVASGGFGVIHAGRWREMRVAVKVLYNSADFIQEVTIHKLVQDSENIVKFYGITQIRSTGDYGMVLQYAGKGSLRDYLSKHFDSLDWANKMRLARDVTAGISFIHEDNICHHDLHSRNVLIDQSGRALITDFGLSRYLNNATSNNGVRGVVPYISPERLKNAPFDHSSDIYSLGVIMWELTSGRPPFSKEENFMLPYEIITGRREEIIPGTPVEYSDLYQQCWDGEPVNRPHVRDILKTLNHMLTRHNGEEAEAKGTIQPVPPRDLSGPRSLPTGTTGQTSTALSRNSEPIVGQMTSADNAKAAGGPTKSLANVKPLQVKGRDRSVTFSPPDFEHGSALRDRFSQVVISDGQSVNTPPTPNRLHWIHGPAQPTGGGGGSPVRSVSPKPPAATYVPHDMSRQSPTSGVISAAIPEIGAVEDFDEKGDPAGIPSYPQHQPKPVYKPHTISNSSNRPTELATPTRMNYPPSVTPYAPPLADWMPRDGKSRIRDFFTACRNGNLEAIKWHLAHGANVMEPYDTMSGRTPLHAAAMSNNLKVMTLLCESAGPNLNLNELDDGSQTPLHLLTQFGDNNDLLEYMLKMGANPNIQDSERRTPLMTAVILNDNAVFIETLLDYGADPNIKCQENNALAEAAIRLRYHCVKVLLDTDLSMSEQSSLLHAMDVCYRVTESVNRNLVLSLLVRWKHAEGLQKRQTLATMILRGSLPFGEKRIDQRRLARQVLAAASH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQN3</accession>
    <name>A0A9P6MQN3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">MCCC1</name>
        <name evidence="10" type="ORF">BGZ80_001581</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>biotin</name>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001362">
        <property type="protein sequence ID" value="KAG0010339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQN3"/>
    <dbReference type="OrthoDB" id="196847at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004485">
        <property type="term" value="F:methylcrotonoyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06850">
        <property type="entry name" value="biotinyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.20:FF:000003">
        <property type="entry name" value="acetyl-CoA carboxylase isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.20:FF:000028">
        <property type="entry name" value="Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.20:FF:000010">
        <property type="entry name" value="Propionyl-CoA carboxylase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.700.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005481">
        <property type="entry name" value="BC-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001882">
        <property type="entry name" value="Biotin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050856">
        <property type="entry name" value="Biotin_carboxylase_complex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011764">
        <property type="entry name" value="Biotin_carboxylation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005482">
        <property type="entry name" value="Biotin_COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CPAse_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048429">
        <property type="entry name" value="MCC_alpha_BT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18866">
        <property type="entry name" value="CARBOXYLASE:PYRUVATE/ACETYL-COA/PROPIONYL-COA CARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18866:SF33">
        <property type="entry name" value="METHYLCROTONOYL-COA CARBOXYLASE SUBUNIT ALPHA, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02785">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00289">
        <property type="entry name" value="Biotin_carb_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21139">
        <property type="entry name" value="BT_MCC_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00878">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="Rudiment single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50979">
        <property type="entry name" value="BC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00188">
        <property type="entry name" value="BIOTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0092">Biotin</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin carboxylation" evidence="9">
        <location>
            <begin position="1"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="8">
        <location>
            <begin position="113"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoyl-binding" evidence="7">
        <location>
            <begin position="588"/>
            <end position="664"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0010339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="677" mass="74302" checksum="33182852095E5D7D" modified="2023-09-13" version="1">MTSGEIACRIMRTAKKLGIKTVAVFSDADRNALHVKMADEAYNIGPAASAESYLKVDKIIEVARLSGAQAIHPGYGFLSENAGFADRLAKENITFIGPPASAMTSMGSKSESKFIMQAAKVPVVPGYHGDNQDDAFLKAEAAKIGYPVLIKAVKGGGGKGMRIVDRPEDFEIMLESSRREAMKSFSDDKVLVEKYLVTPRHVEVQVFADTLGNAVYLFERDCSVQRRHQKILEEAPAPGLSEELRRELGEKAVAAAKAVNYVGAGTVEFIMDNTDQKFYFMEMNTRLQVEHPITEMITNTDLVQWQLEVAAGNRLPKLQNELKKDGWAFEARIYAENPSNNFLPDVGPLLHVQTPEASDSVRLETGFVQGDEISVHYDPMIAKLVVHGENRTAALRILRKALSEYEVVGLNTNIEFLKTLASHPAFIAGEVETGFIKKYEDDMFKPAPPLDHATVAQASLSMVLRDLEATKQAAVIAEDASSPFTLDAGLRLNQLSEQQLAFKLEDQDVKVGVEFNRDGTFNVRVNTPNKTTVFSKVMAKLAGDSSLIAEIENRRYKTSVVQKGDKVHVFAEEGKVTLDVPQPKYLTVGKEEKAGSLRTPMPCKISQVMCKPGDKVVKGQNLIILEAMKMEHVIKSPIDGVISDVFFSIGEMVGENKSLIAFEEAEGAKVAEGAKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQS1</accession>
    <name>A0A9P6MQS1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">S-(Hydroxymethyl)glutathione dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">FLD1</name>
        <name evidence="6" type="ORF">BGZ80_002458</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001607">
        <property type="protein sequence ID" value="KAG0009377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQS1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051903">
        <property type="term" value="F:S-(hydroxymethyl)glutathione dehydrogenase [NAD(P)+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046294">
        <property type="term" value="P:formaldehyde catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000003">
        <property type="entry name" value="S-(hydroxymethyl)glutathione dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43880">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43880:SF12">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE CLASS-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Alcohol dehydrogenase-like C-terminal" evidence="5">
        <location>
            <begin position="55"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0009377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="229" mass="24340" checksum="1DD6557EAC69DEBF" modified="2023-09-13" version="1" fragment="single">EYTVVCEVSVAKIDKAAPLEKVCLLGCGITTGYGAVTRTAKVAKGDSVAVFGLGGVGLSVVQGAKQAGANPIIGVDVNPKKEKLAKEMGCTMFVNSKELPEGKTIQQYLVEITDGGLDYTFDCTGNVHVMRAALEACHKGWGESIIIGVAAAGQEIQTRPFQLVTGRVWRGSAFGGVKGRTELPGLVQDYLNGKIKIDEFITHNFGLDDINKAFDAMHDGDCIRAIITY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQS3</accession>
    <name>A0A9P6MQS3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Sphingomyelin synthase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BGZ80_002124</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sphingomyelin synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001514">
        <property type="protein sequence ID" value="KAG0009729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQS3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047493">
        <property type="term" value="F:ceramide cholinephosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033188">
        <property type="term" value="F:sphingomyelin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045221">
        <property type="entry name" value="Sphingomyelin_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025749">
        <property type="entry name" value="Sphingomyelin_synth-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21290:SF25">
        <property type="entry name" value="SPHINGOMYELIN SYNTHASE-RELATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21290">
        <property type="entry name" value="SPHINGOMYELIN SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14360">
        <property type="entry name" value="PAP2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0746">Sphingolipid metabolism</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="153"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="180"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="426"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="Sphingomyelin synthase-like" evidence="11">
        <location>
            <begin position="126"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="335"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="399"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="454"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="399"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="411"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="485"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="509"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="533"/>
            <end position="547"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF14360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0009729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="547" mass="63434" checksum="CFBFBD9049D6C654" modified="2023-09-13" version="1">MFMAFCNQLSDNRWVETNYTKVLLSDRGFDVIAAQADIRPANNFVMTSIVFTVLGIGLICPDWTTRAMVVRRIMWVIGTLGAYRSLTLSVTTLPTPKEECRPSLKTGFWDMFIVALQMIPGTVEACTDDIFSGHTVFMVTCAIQWRLYCKNKWVTYFAYLYISVGLYFVVATRLHYTVDVILAIFITYAVWSIYISIIEVVMEEEYFGVKSHHEKYSTFDNTVAEYEFSQEELDCAETEGDDGTYTIRSSTLLQRRRQLEHALNRLRGPRIGYGRGEYDRVAFIPMQFNVWLKNIIRWCDGLDLRMRPSAEVSSTSPSRWEELVVRYRAGQVSGESVHDFQSSSRTSRKTEREQENDATYEYEDREEMVQVYNDGSFPMHNYTNESRQQYSQGRWRSFQLNSSSQRSRSPNAKEDKSEKTKSDKKIHILKVAFLILVNAILLIKIVDLIESRVASGPPSQWPKEMEAYPGGSINNNEPSPVMAGSTENQPQPNLEQRSGETNPESNNWYHDRDINHRHEGERRRRGDHHRDHRNHDEKRDWEPEGAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MR70</accession>
    <name>A0A9P6MR70_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_001482</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001339">
        <property type="protein sequence ID" value="KAG0010433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MR70"/>
    <dbReference type="OrthoDB" id="6499973at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17352">
        <property type="entry name" value="MFS_MCT_SLC16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF284">
        <property type="entry name" value="EG:103B4.3 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="122"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="151"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="176"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="208"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="240"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="313"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="349"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="377"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="402"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="437"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="472"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="5">
        <location>
            <begin position="81"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0010433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="516" mass="54499" checksum="34A4757E809FEFBF" modified="2023-09-13" version="1">MAPPMTPCDADETPRTSCEIIPTYSVYTARNPPCSPNSSSTSPKPMPEKNIKSTAPSIIEISQSPTLVDISDRAPDGGLRAWLVVLGSFLIHCFCFAPTEYIFGIFEQHYLELYPSSSHGSIAFIGTLGSSVTYFAGFVSGVCADKFGYRITALLGTSVMTLALILASFANQVWQLYLSQGVLLGIGASLVYYPAIGAPSHWFDAKRGLALGLAVSGTGLGGLGLAPATQAMMDAIGVNWSLRVLALVCLVVCGGASFLIIERENGKKMPEPAPTITDVEIGQITEKLSPEKKNPTGITGFFSELKVFKNPQFLSLTFAEIAASIGFLIPLYYFQTYSLFIGLTAQDGALIAGLSSGASCLGRIILGYAADRLPKTVVVSCCAWITAGSILIIWTLSKSFGVYLFFALVYGFFAGGYVSLVPLVVSETFGAHQLSTVIGFMYAASGIGMLAGAPVAGMILDATKPNVTYLPVIMTAGGTLLLGAICVSLWVFFRRQAKKAKRDGVASSAASAIADL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRW0</accession>
    <name>A0A9P6MRW0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glycoside Hydrolase 20C C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001167</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001260">
        <property type="protein sequence ID" value="KAG0010816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRW0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015929">
        <property type="term" value="F:hexosaminidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.670">
        <property type="entry name" value="N-acetyl-b-d-glucoasminidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041063">
        <property type="entry name" value="Glyco_H_20C_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038901">
        <property type="entry name" value="HEXDC-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21040">
        <property type="entry name" value="BCDNA.GH04120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21040:SF8">
        <property type="entry name" value="BCDNA.GH04120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18088">
        <property type="entry name" value="Glyco_H_20C_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside Hydrolase 20C C-terminal" evidence="1">
        <location>
            <begin position="143"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0010816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="398" mass="45837" checksum="22F74525D9E01046" modified="2023-09-13" version="1" fragment="single">LAGYYDGGTPQLADTLPPDIDLVYWDYYHTSSSSYASKIEQHRELGCANPWVACGAWTWNRFWCALPFSFATIQASCQASKRKDHGVKNMMITIWGDEGHECDMFSALPAMYYFADHGYTLEDEIDYDRLKKCFEGVCGANFDDWVYASKIDQVSDADTTMTLKTHFAPNTSKYLLWEDPFLSHISPQYAHLDLETHYSEIAQKLSKALEFKEEHPQNSHLRMAYLVATVLSLKCHLHSRMALAYQLGHRQELFELTEGRLVDLQVAVDQLWKYHRSLWHKTNKPFGWEVVEMRYGGLRTRLMTMRERILEYIETSGALQRQQQQEQHQVPLEVGSAASVNSQSGLSGFMQRRRSLADGEDPRPCIPEFETIREAMYEYAGCNLLMDYARVSTPTRPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRY4</accession>
    <name>A0A9P6MRY4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Proteasome subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">PSMB7</name>
        <name evidence="11" type="ORF">BGZ80_000789</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Cleavage of peptide bonds with very broad specificity.</text>
            <dbReference type="EC" id="3.4.25.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the proteasome complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the peptidase T1B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001173">
        <property type="protein sequence ID" value="KAG0011294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRY4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019774">
        <property type="term" value="C:proteasome core complex, beta-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004298">
        <property type="term" value="F:threonine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03763">
        <property type="entry name" value="proteasome_beta_type_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000005">
        <property type="entry name" value="Proteasome subunit beta type-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000243">
        <property type="entry name" value="Pept_T1A_subB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024689">
        <property type="entry name" value="Proteasome_bsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016050">
        <property type="entry name" value="Proteasome_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="METALLOPROTEASE TLDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194:SF4">
        <property type="entry name" value="PROTEASOME SUBUNIT BETA TYPE-7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12465">
        <property type="entry name" value="Pr_beta_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00141">
        <property type="entry name" value="PROTEASOME"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00854">
        <property type="entry name" value="PROTEASOME_BETA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="6 9 11" id="KW-0647">Proteasome</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0888">Threonine protease</keyword>
    <feature type="domain" description="Proteasome beta subunit C-terminal" evidence="10">
        <location>
            <begin position="229"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8">
        <location>
            <position position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR600243-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF12465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0011294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="274" mass="29642" checksum="847B56F8EBB68F51" modified="2023-09-13" version="1">MTSRLPRTKGGFNFDNHVRNTMMEGKGLCLPKATKTGTTIVGLIYKDGLVLGADTRATAGPIVADKNCEKIHYLAPNMYCCGAGTAADTEMTTALISSQLELHRLSTGRQARVVTAMTLLKQMLFKYQGHIGAALILGGVDLNGPHLYTIYPHGSTDKLPYVTMGSGSLAAMSVFESRFKADMEREEAITLVKDAIEAGIFNDLGSGSNVDVVVISKDNVEVLRNYAKPNERGIKEASYKYPRGATQVLKTSIRDLVDIKETVQATTTEAMDIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MS77</accession>
    <name>A0A9P6MS77_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Developmental regulator flba</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_001290</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001292">
        <property type="protein sequence ID" value="KAG0010650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MS77"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009968">
        <property type="term" value="P:negative regulation of signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04371">
        <property type="entry name" value="DEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.167.10">
        <property type="entry name" value="Regulator of G-protein Signalling 4, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000591">
        <property type="entry name" value="DEP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016137">
        <property type="entry name" value="RGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058855">
        <property type="entry name" value="RGS1/SST2-like_Fungal-DR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036305">
        <property type="entry name" value="RGS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044926">
        <property type="entry name" value="RGS_subdomain_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10845:SF192">
        <property type="entry name" value="DOUBLE HIT, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10845">
        <property type="entry name" value="REGULATOR OF G PROTEIN SIGNALING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00610">
        <property type="entry name" value="DEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00615">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25889">
        <property type="entry name" value="WHD_Fungal_DR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00049">
        <property type="entry name" value="DEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00315">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48097">
        <property type="entry name" value="Regulator of G-protein signaling, RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50186">
        <property type="entry name" value="DEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50132">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0734">Signal transduction inhibitor</keyword>
    <feature type="domain" description="DEP" evidence="4">
        <location>
            <begin position="229"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="RGS" evidence="3">
        <location>
            <begin position="457"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="205"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="408"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="576"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="658"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="754"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="865"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="208"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="415"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="443"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="577"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="603"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="664"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="692"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="707"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="770"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="799"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="812"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="865"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0010650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1014" mass="110427" checksum="4E40EF616003A67A" modified="2023-09-13" version="1" fragment="single">SPYIPPVSASQLFTDTIAMRTTTSGRPFTKDMIDLFSALMTSIRVENHKIRFKSYPNTFLADDAVSKLGSLPSVRSVLAADPNDPTRVITQIVTTHLSFSRDMAKNICQSFMDARLIESATDPTKREFQPKALYQITPKGAHLLAKFIHRNKMSLEDTRHLTTNATASLIYLDRADDEDAIILGQDHVDIIFKRFAGLEPNVARANSSKDSSASSTVSGRERTPSATDLSNGVEVREQQFNGETFKDTFYGRVAVEWLLDYSTVISKEEAFCTCQEMVSAGYIEQVGEENVGGRSLFRSGNSAFYQLTLSGKVLAGWQVLDDGTSSISNEWTDDASIVGSNAERNNLDVSLLSTQFKLTSTNVSRLPISIKDQQRSVDESNVTGFQYNEEAARHSIRRLSQILNDPAFQNSASEGGTKSSYAASSSGRESAGANSGGGARIPTPSSSVQSTISNTSRLNGILSDPIVRDLFKSFLKQNICEENLSFYLEVMDYKVKFTALISSARAYDQSVFGQNLGNSKHTYPPSLRELEKQICMQAFAIFETYLVSGAPREVNLPHQMRQDITKYMQAVVRNMETPETNGSNENKNLPSALPSPRKPPTVAISNGKASNRGTGTQKELIHIALFDDIHDHIFRLMSTDSVPKFIKTDKYLEVVMSKHKRKNGSSVSSTGSSSPTLSNLDASGGLISNYPGNKGNKTSNSGGSRKNKGEDNTSTRNEDLLLRRSVSYGDHRQFDPVDSFDAQYGNYGGVAMDSRSKSAGMGQPSPRHMNGQTFTASPQFKTPRVRTASSNSSVEAVQPSTSGTPVPVSSSKNKPNASGGSSVSRQAPASLMDIYMQQQQLQGYSNQRAQLSPCQVQQMYMVRNSRPSAASPLSSSSSTAGPVNSLSRPVNVITAPAHADNGTLNCTITSNQQVKSGDQKITVLFESTSLIVEDSKAAEVQQQQEEEKEERPYGATAVNAASETAQSVVWMAEMNDALPASYLNGRVNMDSNNGGMMYIDPAVMTANTMVPQPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSQ6</accession>
    <name>A0A9P6MSQ6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_000089</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001010">
        <property type="protein sequence ID" value="KAG0012268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSQ6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039646">
        <property type="entry name" value="ZNHIT2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15555">
        <property type="entry name" value="ZINC FINGER HIT DOMAIN CONTAINING PROTEIN 2 PROTEIN FON -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15555:SF0">
        <property type="entry name" value="ZINC FINGER HIT DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="45"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="103"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0012268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="627" mass="70934" checksum="2E524F6D759A65F3" modified="2023-09-13" version="1">MSELQSNPSVMPQDRKKMMGILDRFEKQAIDQERMLDKSEDEILQQIQRQQQQQQQQQDSHGKEATSRNNIGGGAAPRKLSSKERNELIRRTIEEEQKEALGEEQYQRQGGEESFAIDPKDREEMDRILEQEHQDLINRFQGVNLDEESFESIWTRLSPEERQEFRERFMISRLSGENDVEDGGIDIEEEIATGTDSRNHRSASVDDDEEVEARKLLQEMGETLKRGGEKVGDSDNNDPMMADLDSDDLRAIRDAEISDLIPIWKPWWEIEAEQAGQLKKVTVSQVSDKDESGRLNAGSIDSKSQPIGTFAEKSSVVAEKFVLDEEAMLWPQRALVQDLDEAEEEEKQRQLTAATVPRMTRAPHPALIYHICALLFAYVATSRVLNGDLNEEPEQTLAYIFDICPFFSPPPPAPLSKSSHTPLSPPAVATQDIPDVDDFETTLAILQTSSLNSKLWKGDTLRLEMLSLLLRDLTLILARPSRSLRSIQQLKNVFNSCMGSIGPSPKGDSSLEEDRGKIGAAQKRTRLFSKSVLHRLFKKLEFYESYLVSDEYLLKTDRLDQIRTEVVMAGIRVRQEMLGWTQELENITRVNEATDSNAADSGDVVGAHDIGAKESFGAKKVLIEELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MT71</accession>
    <name>A0A9P6MT71_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_000194</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001033">
        <property type="protein sequence ID" value="KAG0012116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MT71"/>
    <dbReference type="OrthoDB" id="2399390at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="592"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="677"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="595"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="615"/>
            <end position="626"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0012116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="749" mass="85904" checksum="B4F72AB37B100C32" modified="2023-09-13" version="1">MPLLNSLRRKSHQNQSKPSNAGLSDPLKSPQPRESQSQLTVLNRQTAPAHNILFLPEFLYPLFSCLDQKSILSVRLVCMQWSSVARPYLTLTTQWRDDLSRDQKAEVAARLALVNTLEVIDADDTWMKIGDSMREAPTLVDGCSSSNVPTSEDPLFLALQELMVVGDTSQYREEREFARKVRGSTLANRRQIQLQKLILTKVQKFEKRLENLLEIFPMLTCLELVDAVNAKVDMNIVLEVCPNLRRFVLEFALSDEILWTTTTSNNKQQTTSITASILETPSHSVFIHNLDTLILRHAKMDQVSLESLCAALPNLLSIEVRFLRVIQVRGDSVLFNRRGFYRSLARSCPRIESLHFSLYHCSLTEKDSVTLQDSFPVLKELSMAGKDLDDRVFGHRYKLLEYYSNFLTKLEILCYTTSQSTRFLERIHQFLCSARHLRHLIAPRLQYLTEYLDLVEAYDPEYNTRSHEHEITFYRPRSVAAGQSMEWKIPVRQWACQDLETLHLGFTALYGSSTDAEHSRVMFGHISRYCPRLKDLFISKQTLNLHIDGGLCLLTRLKHLERLKISSHTKYFNLEVSDIDWIGQLVPVEAETDPANPSNFSKSNSSRLKPLKSNPPKSNLSNTVSASTPMTAVRAKKSADYFKSLVTRVKGKSTFVTPVPARRTIEDVFEIDREWNKRQRHGQVSSTTSDLRDRHSNRQLSEDSESGYLHWRLLHSFTLEVDPTHLFKDSSGIALMKKLRPDINFKVPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTG4</accession>
    <name>A0A9P6MTG4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_000275</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001050">
        <property type="protein sequence ID" value="KAG0012010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTG4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY MULTIDRUG TRANSPORTER MFSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718:SF9">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY MULTIDRUG TRANSPORTER MFSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="185"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="207"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="237"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="256"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0012010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="288" mass="30843" checksum="37BA0FEB44C075F7" modified="2023-09-13" version="1">MLISRVRSKIVLIIGWVFMIASGVMWAQLKADSSYWSIPFPSFIVNVIGMGAIWLTCQINSVADAADEDQGVVGAVFNVSLQIGAPLGIAISNIVANNRNGPFAVGTELLPGYTDAFYSYSVMGGVGLVLTLILYPNSDAIQSHTSTKGSDIEAGMDISGDDEEMTIECSGVIIEGASDMKVVKETDNDERDDSQLKVVENSDDECETKVAENSDDDSKTKAVESSDDECETNAEGKSGDDSQTKAEEKSSDDDGETKKVEEKAEEKTDDDSETKTTEKTKSANTPDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTR7</accession>
    <name>A0A9P6MTR7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_011206</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000874">
        <property type="protein sequence ID" value="KAG0013239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTR7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0013239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="473" mass="54471" checksum="1A785198B844F05B" modified="2023-09-13" version="1">MEPLVITRVAGEVVPIIGFEVWQIGALHCRSFFEFDDEWVDQIFFPAIERNHGLETLIIQFFPTPLMTSDSYFSLFKRLLDPLRSLTTLYLAMRYGIEHKAFVYVAGFSKQLQRLHLTFASIIFDGETDEQYRIDTLGIKPTQLKQFELDFTLPPMVELHLIPILEASPELETLLIPTFESASTERIASVLGQCCPKSRDLVHYQMGSKLTDGDIAEIIGSCRASGLRSFCMTSGRHAAGLQVMRRLCANYATLVKIRVDLEGLEPFKFVQELLASCPNLRRLHVEERVPGNTTGRFAVREILRKPWVCTNLESFSIPLAGIYGIIEGEENESQGKDYHRDLYTQLAKLARLQELSVGFLLCYERMCKTSPRFSLKSGLEILEGLKELRSLTLHYMVNDTQRQELEWMCEHWSKLTRIDGINLEIAESWWDFERDQTGKKVTLMPKRIREMLIKGEVPYHGPNKYDFDSDELY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2024-01-24" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUB2</accession>
    <name>A0A9P6MUB2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_011365</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000904">
        <property type="protein sequence ID" value="KAG0013008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040279850" evidence="1">
        <location>
            <begin position="31"/>
            <end position="2320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0013008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="2320" mass="236624" checksum="1E0852F087148F6A" modified="2023-09-13" version="1">MSPSFQSRMALAGIAGLAVLGSTLAPSADAAITFGASVDSPGSIVMGCLSAMVPTSSTTSGSTSLLDQYLVPGLVNLTQAGFNITSPTQIVLSVNGSLNNPFGSVSLPLGKVGVQVILDGMSLANITTSDLTLPGGTGPLNVSATIDIADGNTNPAMKTSITNLVYGLFGTSTSNGTTSDLVISDLTLSGVSLGIQPITIPTTPILSANVSLSDLISSTSSTNSTSESVVGVSGLYNSSIGFTSPTITKLTIKAVSGAQLTAGVGFTWENPLNVNVDIPYVSVDLGLNGTRIATIGVEGLHLSPGTMSGEILVDLQFNNDAVASAQLGALINGFFDGSLNQIVNIGNLTIGAEGNTTATGILLNNLFSGIEIDLPLLDISTAFYAQILLGYIAPSLPIDISNLSSSGSSLSSYLKNLAISTAAGHTLLIEPKIQLPLDFELDLDIPYLALDINLEDNLLGELFLANLMGSGSGEVDISVGIGIVFSEPAPEIPPIVAKIVNGLTTGSSLDVLVGVSNLAIGVSPSDAINTLNNINMAASISDFITGSLSIGGSDVASETSVTVASNAIAVKIGSLVSLTIHEASISVLPNNLVSVGINLDMFLGIPVAANIGYFGVQLSLDGINLAGVDLTSGLNYAGGTAEMEMNIAILVGTGSDISGKVASLVNAIIANQTISSSLGIGRIVIGQSSSDLIKALSDLSFSVSLDGLSGSSTSSLSTSSLDSLITQLGLSVSDLSLATISDAGLQIGAKASFSDPIPLSLSVPFIGVSGGLDNVDIANVGLNNLAMAPGANAIQTQVDLNFNNAAEAQTKVATFVGEIVGGQLGSTPEALTVHNLRIGASASDYFDILSQIDVSIPSKDILTQANVNSLLSKLGLNTTQASGDLLSNLHLGAISVNLNNAPVIELGTSITVSNISLNAAVNIGYFGFDVALDADALAYIDVPSITISTANSQLSLAIKAAITVQDTTQIETDIANLVNYFTANTTTSPVNDLVISKPLLGVSTSDNIQTFSLITVSIPLSSLLVEAKAYVAKMLSGLGGMSTSSLSLSGIVVDLNSPSTINLQGGVSIASLTLPADISISYVGASIALDSIPLASVTIPMLNLTSANNALSVNFQALIDLQEGQDASAQVAKLVGSLLYPGQVKFSITLAPYLEQIGTLLSGTTSGSNLLSDLDIGSLVIDLNSPQTIGIDAAISIKNVTIPAEIKLNYVGINVAIGAVGLANIAVPSFTLASSNGALAITAHVDVTLLPSDDLTTAITSLVTDVLSNKTASTTNLVLSGAVFGGSSTNVFTILQGIAIPINVAPYINELPTLIAGQNTLSSKVSFGAFVVDLNSPQVIGIDTSVSIKDVTLPAQIELSYVGANVAIGQVPLAELRIPKFSMTPSNGDLDISLHLDLALQESQALTQTVSGLAQTILAGKSLDTTSLVISGAVFGGSSTKVFTFLEGVKIPLDVTSYLNQAIASFGQDSTSSLLSSITVSDLVVDLNAPQVIGIDAAVLVKNVTLPAEIKLNYVGANVAIESVPLAQVSVPHAISGLVSAVLANETLSETDLIISGVTFGASSTNFFTILEGVTIPVNIATYIAKIGNTLTSAGSSLSSIGLSDLAINLNKAPTIGIDADVAIHDLTLPAMLNVGYVGLTIAVNDVSLADVSIPKIQLGTSGTDLTIATHVDVTLEDTDASQTVVAGLVDNIIAGQTSQGTIVISGIAFGPSKSNVYTILEGVQVPIPISKVLSLVSTTSTSTSTTSILNNLSLQSADINMKNPPSIGADIVVALTGYQFDAQLLLDYVSISAFLDDTSLATISVPDITLTSSDNKVALSVQSLINLDSSSAIQTKVAAIAAEVMGSSGSQNVSLVISNIAFGGSASSTFHILDKVKISIPLASYIQELTSAVSSLTSSSSTSAFSISKLDIGAPDANDLTVALSASISGIGSKISVEMPYIGVQVSVGDTGFVYPTINNFQLSNGNIALTLDLAFQSGASKIVSSLSDPVSELLFGTLGTVSGSIVINSVVFGASASQSFDIASKIGLEIGLNSVFQAAKTFLSSSSSLSFSDANTVMTTTGIQTTISISGASLGSLPLKVDFPISLSCLYNGDAFIDIETTSMSLTASPWAIGIKADVIEPEFGTAMSAIIPNTLEWKNILEGVTIGKLALGACTVLSELVITPPSITLWSPITIPLNKLTPHLSPLGMDFAISFVNGGPLQLDIGSIDIMVTKGTTQILEIQNIGGPLQLYGSSQNGGQNLFSMNVALKFNILELITVIPSLLNPGTSYSFSFSTTSSSGDTMPWLQDALNGVPDSIYSNLLPILANALSNVKFTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUG8</accession>
    <name>A0A9P6MUG8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Cytochrome c oxidase subunit 8, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Cytochrome c oxidase polypeptide VIII</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_010738</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Energy metabolism; oxidative phosphorylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Mitochondrion inner membrane</location>
            <topology evidence="1 7">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the cytochrome c oxidase VIIc family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000780">
        <property type="protein sequence ID" value="KAG0013985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUG8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045277">
        <property type="term" value="C:respiratory chain complex IV"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006123">
        <property type="term" value="P:mitochondrial electron transport, cytochrome c to oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.49.10">
        <property type="entry name" value="Cytochrome c oxidase subunit VIIc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004202">
        <property type="entry name" value="COX7C/Cox8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036636">
        <property type="entry name" value="COX7C/Cox8_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02935">
        <property type="entry name" value="COX7C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81427">
        <property type="entry name" value="Mitochondrial cytochrome c oxidase subunit VIIc (aka VIIIa)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 7" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU368123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0013985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="74" mass="7823" checksum="36118AB01CDEEF01" modified="2023-09-13" version="1" fragment="single">MNAAVFARTGIRARATIGATPLRSGAYHFSNENGKNIPFSTKNKPALAFGVVAYLGTGFALPCVAGYWQPYEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUH0</accession>
    <name>A0A9P6MUH0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10 11">13 kDa ribonucleoprotein-associated protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">NHP2L1_2</name>
        <name evidence="13" type="ORF">BGZ80_010641</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 11">Common component of the spliceosome and rRNA processing machinery. In association with the spliceosomal U4/U6.U5 tri-snRNP particle, required for splicing of pre-mRNA. In association with box C/D snoRNPs, required for processing of pre-ribosomal RNA (rRNA) and site-specific 2'-O-methylation of substrate RNAs. Essential for the accumulation and stability of U4 snRNA, U6 snRNA, and box C/D snoRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of the U3 snoRNP particle. Binds to the C'/D and B/C motifs in U3 snoRNA. Component of the 25S U4/U6.U5 tri-snRNP particle, a subcomplex of the spliceosome. Binds to the 5' stem-loop of U4 snRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
            <location evidence="1 11">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the eukaryotic ribosomal protein eL8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000761">
        <property type="protein sequence ID" value="KAG0014126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUH0"/>
    <dbReference type="OrthoDB" id="1924699at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd21104">
        <property type="entry name" value="SNU13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.30:FF:000002">
        <property type="entry name" value="NHP2-like protein 1 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050257">
        <property type="entry name" value="eL8/uL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002415">
        <property type="entry name" value="H/ACA_rnp_Nhp2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004037">
        <property type="entry name" value="Ribosomal_eL8-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004038">
        <property type="entry name" value="Ribosomal_eL8/eL30/eS12/Gad45"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018492">
        <property type="entry name" value="Ribosomal_eL8/Nhp2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23105">
        <property type="entry name" value="RIBOSOMAL PROTEIN L7AE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01248">
        <property type="entry name" value="Ribosomal_L7Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00881">
        <property type="entry name" value="L7ARS6FAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00883">
        <property type="entry name" value="NUCLEARHMG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01082">
        <property type="entry name" value="RIBOSOMAL_L7AE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 11" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Ribosomal protein eL8/eL30/eS12/Gadd45" evidence="12">
        <location>
            <begin position="20"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00037456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00040411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU366039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0014126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="126" mass="13669" checksum="140C23A81FC80CD6" modified="2023-09-13" version="1">MAEANPKAWPLADAALTNSIMDLVQQASHYKQLKKGANEVTKTLNRGIAEFIVMTADTEPIEILLHLPLLCEDKNVPYVFVPSKTALGRACGVSRPVIACSVTSNEGSDLKAQILAIKLQIEKLLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUQ8</accession>
    <name>A0A9P6MUQ8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein phosphatase pp2a regulatory subunit a</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_011382</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the phosphatase 2A regulatory subunit A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000908">
        <property type="protein sequence ID" value="KAG0012971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUQ8"/>
    <dbReference type="OrthoDB" id="340346at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000159">
        <property type="term" value="C:protein phosphatase type 2A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019888">
        <property type="term" value="F:protein phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000011">
        <property type="entry name" value="Serine/threonine-protein phosphatase 2A regulatory subunit A alpha isoform"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055231">
        <property type="entry name" value="2AA_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000357">
        <property type="entry name" value="HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054573">
        <property type="entry name" value="PP2A/SF3B1-like_HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051023">
        <property type="entry name" value="PP2A_Regulatory_Subunit_A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10648:SF4">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2 (FORMERLY 2A), REGULATORY SUBUNIT A, BETA ISOFORM-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10648">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A 65 KDA REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02985">
        <property type="entry name" value="HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22646">
        <property type="entry name" value="PPP2R1A-like_HEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22956">
        <property type="entry name" value="VPS15-like_hel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="11"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
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</entry>
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        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
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                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
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                <person name="Grigoriev I.V."/>
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</entry>
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                <person name="Grigoriev I.V."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="979"/>
            <end position="1005"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1069"/>
            <end position="1089"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1091"/>
            <end position="1102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1103"/>
            <end position="1117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1118"/>
            <end position="1127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1130"/>
            <end position="1139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1143"/>
            <end position="1152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1158"/>
            <end position="1169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0015940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1233" mass="131824" checksum="FC7CCB3BA6E93BB9" modified="2023-09-13" version="1">MTTSEDSNVLRQLLNQIEGELNVTPTFNDTNGERSDQSRASLVTSQEGSLSGSAIPSAANGHLPQRQQSPFPLPQQQHSFPTTATSAIFGNAFDRPALQSQQSHHQPGFGAPSLIMNSSYFQGPRAPQYIPSPLASPVSPNYTEKNISGTDLEGDQSPTTEKSRAKPLQSQGSFSSVAADLAQADRQDNVAKADSLTEEQTKEQETDHEAAAQCIPIDQEPNQDHHYDDDIKVDVTELYESFGQKPSLARQDAMDPEGVVEEEERIRYAGGLVPPENTSQGSSSLKLSELTFSNNELISLWSPTTGSASESLGVDGTEKRTRLHTFHGHSEASQEKDQLAASSLGSSTANSLGPSVTFPPKQQSTTKTECPSSQGLMQGLSVTEEVVTVAITDGNSDTTIIETGGPTWDLAPLSPPVEAVETVSTFATASHMSVRGGPMIQTQQDSNVMESQQLNGIMSPTSATTMTPTTPLTNREARILAGREALLRWAPDKQRVQRGVSASSTSSSISSIEKPGSTTSSGDGNDTVTLTDPLDASRRASVKSQNSQQSQRTYGGIYGAIPERGQLTDVPPEKLIFPDQSIRAAPLKAYKVRRMTLRERNETYVQACQELTRARTGLDVWVLRCMMQDHPGLMKDPPAIVKAVIAGSTHQNFDTQSKASNATPTTLHFSNPMANSISGTHGIGAIIKNASKRLSIDASNPQISIPEITGQGSFFYKQKTAKSAVELGSWSSGRVRGISNNSNHAVGTPPPPQGFISHRNSIIAPGVGTISPSPIQQQQQHLRGGLANSPSTGSSFLSQNKRSSIGAISSPLSNTLRNRTMSDVQAGNRLSMIGRDSSVARVNNVDSSTLHQQQQRDAATTSAPINASGNSGQSSSSPSSHTGAPISTTSSVFLERPIQRRMSAHYTRRPASMVVPPSSQRSGPLGNVANNSTSSVSAGSQSSNSIPESTDLKTPATTPSPTSGLKQQQVQPAQNPLQDNSTVSSPSTDNSGATQPAYAYSSNGTPIPYADETKSKDEIYSPLTSPIMIPLGGFPVPRPSHNNSYQNNGGWSSPLSPGGGLTRPLTYAGPSSSLNSSLAMPPSSATRDYSQLPQQQQQQFSQGVSNLERGNSGSSQEPVKDKTEKSNRYSTSSFSSIGSFAKYQKRSSKKDRKKELLEQQQKQQAADQRYSVSAINQSPASANDYLMEQSLDKLSDVLPHVDRDRLSIYLQRAYGDEMVAIGLAMSDFRSGQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWI2</accession>
    <name>A0A9P6MWI2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Inorganic pyrophosphatase</fullName>
            <ecNumber evidence="4">3.6.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Pyrophosphate phospho-hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">IPP1_2</name>
        <name evidence="12" type="ORF">BGZ80_009895</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>diphosphate + H2O = 2 phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24576"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="EC" id="3.6.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.1" evidence="4"/>
    <dbReference type="EMBL" id="JAAAID010000635">
        <property type="protein sequence ID" value="KAG0015365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWI2"/>
    <dbReference type="OrthoDB" id="1608002at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004427">
        <property type="term" value="F:inorganic diphosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006796">
        <property type="term" value="P:phosphate-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00412">
        <property type="entry name" value="pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.80.10:FF:000004">
        <property type="entry name" value="Inorganic pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.80.10">
        <property type="entry name" value="Inorganic pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008162">
        <property type="entry name" value="Pyrophosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036649">
        <property type="entry name" value="Pyrophosphatase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10286">
        <property type="entry name" value="INORGANIC PYROPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00719">
        <property type="entry name" value="Pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50324">
        <property type="entry name" value="Inorganic pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00387">
        <property type="entry name" value="PPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00040300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0015365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="296" mass="33387" checksum="BC34A6D0DC25DA25" modified="2023-09-13" version="1">MSEFTTRVVGTPNTLEHRVFIEHKGTPVSAFHDVPIYADKANNIFNMIVEIPRWSNAKLEISKDEALNPIKQDVKKGKLRFVRNCFPHHGYIWNYGAIPQTWEDPTQSHAETKARGDNDPLDVCEIGEQVGYTGQIKQVKILGVMALLDEGETDWKIIVIDVNDPLANKLNDIEDVERHLPGLIRATNEWFRIYKIPDGKPENQFAFSGEAKNKKYALEVIKETHEAWERLIKGAIPSKAEGYDIQVANLSVEESPYKITADDDIVKAVPDASHKAPAPIDPSVDKWFFISGTSNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWR9</accession>
    <name>A0A9P6MWR9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_009643</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000596">
        <property type="protein sequence ID" value="KAG0015775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWR9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="263"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="339"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="905"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="37"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="273"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="293"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="339"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="351"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="398"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="414"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="917"/>
            <end position="931"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0015775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="947" mass="106180" checksum="6A6CEB6B09C35616" modified="2023-09-13" version="1">MGRPPKNQDTSHLKYGLYTDMYLRMHYMTRPIGSYFQSDSSSSSRSAAEPPPSRSQSTRSNSPCGPDQETLSTDAIKSENVNSGTIKSDTGKDETPTKRDLFDEPFTSQEYETATEEFYDGQTDDNNPFSLNNPFSPSKPTIKEIESPWNDDGLDAELGPIDNIDSLGLMTYSSQPSGESLRRLALSPRKQKIKKDLLPGSVPMPTQTFSEKLAAEMSDSDREDTHLLCLSKTRSPIFAMKKEDALFSNLKKPIAPDFDVKEEDAELSMVEGSDPESEADWNDDEIRKPPPAVSTVPTVAAVASPPKLTVDDVDALLESDDDIPTLGRFTAKSAKFVLDESESDLDDDPFSSNSSELSTPSTATTASLDQSKEKKSIDAGVSDDENDIKDTPMRRTTRTTIRATTPPRKGRILRSSTTKQALSPISPPRPAPKPAKKKPVLFSLDSLLNEKKRRAQIGYDLETAKNQMVLNDELIEEYNEDEEGDSFYGPEAIPKGILSEEQEGALTEIIGDEQIEIIEDVAEFFVRWPQELVVQPLEPELNDADFGDPVVQKALKCTRTDTQRTQFLTSPFLMIISSSPWAMPRSLFRWLVHVVSVEQNQAVTLSVFALLQRTFSQRTSLLGVDHQDLIRAFKTYGAKEEYLEQDWKVTPVTRTTRNERLILPDTKKFPRQNLKAVIKLVNMTATLDPKFYDAVEIRKILNLLLRITTDPIIGDIKSLLGSTMVALLDAIPESSWESERHILCEEIIQTLGTSLPFMLLVLHQLPSLSMRITLLRRSIAGAYLNQPRIPAGETAPNLEELHRALFVDRGFLINSKTVYRDLGRRIQVFGFCLDDEQMIANYGRKALEPLLKKLRLMHGKIVDVRAAFMERTWAKDMIQRLYMRLYYAGIHRQIAKQSTLNFGMSASGEKQRPQIPIVTNQHSTPESTLPSASVKVEETLQPLSNNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MX02</accession>
    <name>A0A9P6MX02_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_008730</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000484">
        <property type="protein sequence ID" value="KAG0016973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MX02"/>
    <dbReference type="OrthoDB" id="443682at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007320">
        <property type="entry name" value="PDCD2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025886">
        <property type="entry name" value="PP2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47524">
        <property type="entry name" value="20S RRNA ACCUMULATION PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47524:SF1">
        <property type="entry name" value="20S RRNA ACCUMULATION PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04194">
        <property type="entry name" value="PDCD2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14299">
        <property type="entry name" value="PP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="31"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="403"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="441"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="728"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="116"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="143"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="405"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="415"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="451"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="483"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="499"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="527"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="739"/>
            <end position="752"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0016973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="990" mass="108548" checksum="0BFC04E4CCC317AE" modified="2023-09-13" version="1">MDHDTHMSDSSHSAERPGFTHEVPSKRSNRKLSLTDMPVEVLTQIALKLPCKEFGRFLQVNRSIHDIANSHYIWHQRFATRFGQSILKSKLEDAKTKPASNTPSRPPSPRFPPDANTNSSNNGSPSTVTSQIYQGYYHNHQDPTSSTSTPVSSVPSSPQSAHSQILAPAGNSSSSDNDERPNDDIAATKDQSVEKGKGRKIDLRKTTEISKDILIELYRQYSRMTLPAEDMQICHMGDRYWKMIESRSSTFGRLAQLQSVWWMDVVAIFRGVPPGRYKVQWRVKVTSDAPIVNSEFRAVLFDKDEEGTSDKPDSIHFKPRNVQEFTERTDTKVTKADRKPFRNLFRKDFTVLELPGDLIIEDDFQNVFLQIRNHEGWKSGLCIDYVRLVDMDDPEKSIHRLVFRGEGSSPPTSGSEEEVNDEGEEYYVTGTSSSLPWFQTALGISPDRSGGNKGNGGGGNKGNGGGGNSSRNNHAATNKKLADTTSSIKNLQIGTSTVSGSKGTNSTSANNSNANGNNKNGKKPKKNTSNGAKSASTPAPAKKSTGPVLLGLPDSPMEHQDDVDPYITKIGGVPSWLDQDMPAPSKYGICGACGKNLYLILQAYVPLERSPYDRVVYVWACNQRLCMRKNGSFRVIRALKLNPEYAQKLEKKSKPAAAPAPITAPGVVTAVNPFAASGAFDMGSALFGGSGSGFNPFAPPSSTVNPFAPPMGFGVGAPAPAVISFASITSTNVPKEDPSSDSEEEEEEEDVASESTEWPENLPAFDPHYLYITEEVLEKSDSIDDDISQRYGHLLALEEAAADGDDEDGAGGSGSGGATWSGEAYEKAALPKGVDKAFQKFTERVQSWPEQCVRYDFPGVPLLFSYSDRTAQSLLPPNVTQHSKHTTPSAHRIPKCPACKGPRGFEFQLMPNLLSMLDVTSKKYLSEEEKQSLKERKGAQVFDIGMEWGTILVYSCVEDCFGMKAQNEESSSDNQKVKYFEEVALVQFED</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MX89</accession>
    <name>A0A9P6MX89_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_009682</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000601">
        <property type="protein sequence ID" value="KAG0015723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MX89"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0015723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="81" mass="9236" checksum="0AE289CEFEC9F492" modified="2023-09-13" version="1">MVPEADVRLQAAYDRNHGNRDDSSKRAQATVAHNQNNKGQRKQYASISGFFLKVEKTCCDIVAFTALWKKSVFEMLRIFSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXE3</accession>
    <name>A0A9P6MXE3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008548</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000467">
        <property type="protein sequence ID" value="KAG0017171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXE3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="279"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="321"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0017171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="436" mass="50021" checksum="5A6D627D5ECE1960" modified="2023-09-13" version="1" fragment="single">MNPEISNRVCRFLYVFRGKLIEEEREILSDEDELDIRPRTLWPDDDTTEHVARDEDYEISPFNSQDPRTRLPWTSECVEEYSPQPDEFIPATDNYTENNEEADANEHDQTPVTPSGNNNLESKPTRSKTATKTKRSRKTKPKQPQGHQELEQTAQSENQQPEPQPVQRIDETSQLHIDNGEEGNEQDKGLEPSYSEDSREQDIQKTPPKRQSKIFEPDSIQPTEDMHNTTPSSIYTMYEPSSLDITEEAQSTTPRRASKTFEPDSLQPTEEDGYESLEFTKQLQENGVTVSEDGYFQPTIPASEDEKYSQRSRSQTPEPTAYDRRHRQETPEPPARPNYAEYGDGVNGNPGEIDRGYRSETVIKVLNGDELEDGHHHHAFRPSSSPSPPPSTPLSPLTKAIPLDNPFQDTPDTRDAHFVLEERENRRLESRHKLAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXH9</accession>
    <name>A0A9P6MXH9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_008291</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000445">
        <property type="protein sequence ID" value="KAG0017421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXH9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050562">
        <property type="entry name" value="FAD_mOase_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356:SF2">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356">
        <property type="entry name" value="FAD-DEPENDENT MONOOXYGENASE ASQG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="6"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0017421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="343" mass="38512" checksum="77710CFDE1D40B2D" modified="2023-09-13" version="1" fragment="single">MSVNVNILPVFEQLGLYDELMGISFTSPGMHIYNENMTKIAYRGNEGIKETVGYDYLVFSRPKLYDLLLSKISREKVHFGKKVLSIKHPAEGGVVINCSDNSSYLGDILVGADGAYSAVRQSMYRELAEKGELPRSDSQGLKIGYMTMVGTTDPLDQATYEHLKDNFTHFSFIIGKGKPYTWSTFTVPGNRICWGVQVQLTQASAEDQSFRNTEWGPESNESMIKEIYNFATPYGPLGQFIDKTPNERISRVFLEEKMFETWYYGRAVLIGDAAHKMLPSAGQGAVNAMQDAVILANCLYDIAADASEKNVTAAFKDFKEQRYPHVQHQFDLSKTMAKVIYGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MY42</accession>
    <name>A0A9P6MY42_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_008674</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000479">
        <property type="protein sequence ID" value="KAG0017026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MY42"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013183">
        <property type="entry name" value="Hsk3-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08227">
        <property type="entry name" value="DASH_Hsk3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="61"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="20"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0017026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="117" mass="12740" checksum="14C6F873FD60A0FC" modified="2023-09-13" version="1">MSSVTTSSAAPTATSRATQYTVLNASLEKLQKNLETLEQNVEITVVQSEWTKRLLTIHSSFLHKPDNVENNGEISGSASSRGKRRSKSPGESTLLIPNDGTSTNASRQEDGEEGEYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MY62</accession>
    <name>A0A9P6MY62_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GTP-binding protein Rho1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RHO1_1</name>
        <name evidence="4" type="ORF">BGZ80_008412</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rho family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000455">
        <property type="protein sequence ID" value="KAG0017307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MY62"/>
    <dbReference type="OrthoDB" id="8830751at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001179">
        <property type="entry name" value="Rho family GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003578">
        <property type="entry name" value="Small_GTPase_Rho"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24072">
        <property type="entry name" value="RHO FAMILY GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0017307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="164" mass="18565" checksum="849438B043324AAD" modified="2023-09-13" version="1" fragment="single">IYVPTVFENYVTDVEVDGKHVELALWDTAGQEDYDRLRPLSYPDSHVILICFAIDSPDSLENVQEKWFSEVQHFCGGLPILLVACKKDLRYDQRTIDELRRSNQAPVTPERGAEVARHIKARDYLECSAKTGEGVREVFESATRASLLAKPKGGRRSNKNCLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYA0</accession>
    <name>A0A9P6MYA0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNA polymerase III-inhibiting protein maf1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">MAF1_1</name>
        <name evidence="2" type="ORF">BGZ80_007547</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000389">
        <property type="protein sequence ID" value="KAG0018098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYA0"/>
    <dbReference type="OrthoDB" id="277029at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000994">
        <property type="term" value="F:RNA polymerase III core binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016480">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1000.50">
        <property type="entry name" value="Repressor of RNA polymerase III transcription Maf1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015257">
        <property type="entry name" value="Maf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038564">
        <property type="entry name" value="Maf1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22504">
        <property type="entry name" value="REPRESSOR OF RNA POLYMERASE III TRANSCRIPTION MAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22504:SF0">
        <property type="entry name" value="REPRESSOR OF RNA POLYMERASE III TRANSCRIPTION MAF1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09174">
        <property type="entry name" value="Maf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0018098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="223" mass="25340" checksum="0B5AFB0955833463" modified="2023-09-13" version="1">MKYLEYPGMDNINSALNFETPECNVYGRVEPYSCKAAGADKKLYKQLENKYPSVGHIMSPPDDDGFNIRNIISPFGPMDQPASRKTLFYLIGTLNASFPDYDFSDVKPEQFRKEPSVSIVVNSINSTLLNLGNERAVKEMGLWDAINQLIEFEDSDVYSYNPESDSDPNNEEGGTFLGLKPEEEEDDDDMYNTDDDDEDSGFGHRRKRNDYDDDFVAGDMDMH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYP9</accession>
    <name>A0A9P6MYP9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GDP-L-fucose synthase</fullName>
            <ecNumber evidence="3">1.1.1.271</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">TSTA3</name>
        <name evidence="8" type="ORF">BGZ80_007514</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Nucleotide-sugar biosynthesis; GDP-L-fucose biosynthesis via de novo pathway; GDP-L-fucose from GDP-alpha-D-mannose: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.271" evidence="3"/>
    <dbReference type="EMBL" id="JAAAID010000387">
        <property type="protein sequence ID" value="KAG0018127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYP9"/>
    <dbReference type="OrthoDB" id="202470at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050577">
        <property type="term" value="F:GDP-L-fucose synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05239">
        <property type="entry name" value="GDP_FS_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00956">
        <property type="entry name" value="GDP_fucose_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028614">
        <property type="entry name" value="GDP_fucose/colitose_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43238">
        <property type="entry name" value="GDP-L-FUCOSE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43238:SF1">
        <property type="entry name" value="GDP-L-FUCOSE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="7">
        <location>
            <begin position="8"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0018127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="322" mass="36377" checksum="98F303B56B6D7B6F" modified="2023-09-13" version="1">MSSEKSVILVTGGSGLVGKGIQWVIENDPKYGKREGEEWVFLTSKDGNLVDPVATKAVFEKYRPTHIIHLAAKVGGLFGNMAANLDYFRDNLLINDNVLHNAKEFGVKKVVSCLSTCIFPDKTTYPIDETMVHLGPPHDSNYGYSHSKRMVDVMNRAYHDQYGCNFTSVIPTNVFGPHDNFHLVNSHVIPGLIHKCYLAQQNGTPFIMAGTGRPLRQFIYSRDLARLFIWTLREYKEITPLILSVPEEEEVSIKQVGDSIVKAMGYTGDYRFDTTKADGQYKKTASNKKLMSLHPDFVFTPFDVALNETVEWFKENVDTIRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYS6</accession>
    <name>A0A9P6MYS6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein CLEC16A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_007946</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CLEC16A/gop-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000418">
        <property type="protein sequence ID" value="KAG0017750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYS6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901096">
        <property type="term" value="P:regulation of autophagosome maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007034">
        <property type="term" value="P:vacuolar transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039272">
        <property type="entry name" value="CLEC16A/TT9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045820">
        <property type="entry name" value="CLEC16A/TT9_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019155">
        <property type="entry name" value="CLEC16A/TT9_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21481">
        <property type="entry name" value="PROTEIN CLEC16A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21481:SF0">
        <property type="entry name" value="PROTEIN CLEC16A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19439">
        <property type="entry name" value="CLEC16A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09758">
        <property type="entry name" value="FPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0072">Autophagy</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FPL" evidence="4">
        <location>
            <begin position="20"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="CLEC16A/TT9 C-terminal" evidence="5">
        <location>
            <begin position="204"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="303"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="362"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="546"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="303"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="362"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="378"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="395"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="553"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF09758"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF19439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0017750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="605" mass="67683" checksum="8911CE098314E56E" modified="2023-09-13" version="1" fragment="single">MLNLLWNKPKPERFSLENLKHFFEEKVHSHFLEILRSKHDGALIVQVLQTLNIMFENVRSQESLCKSKYFLLSKNYVNDVIGLKYDFSNDEILAYYIYLLRTLSFKLSKDTIYFFFNEQLDDFPLYSEAIKFFNHEESMVRIAVRVITLNVYSVNDNQMQDFILDRTTKTYFSNLVWFIGDYGTTINDMLLHPGDGDHSRINYYLAEHMDCFYYVNDIIELEVPKINKILISSLLNRLMRPMYLDSLLPTSALVSKSNRSSTTSPKLMPLVALSLMLHAFHVLKHAPLVSALASTLFSNQHFSSNGSSNTNSNSKSPRHVPSPLVFGVHTISPESSHPASPVTSKFHSFGLLGSSPASQDSYLSVPNTTTPHIHLNSHHSASQTRSPSLNSSILQQRLQQQQQEQQQNPFKNAIYGYLSQVDNDRMVLPALTLVYLAGRNTGVMSDVLLGTDIYPQRLLKSRLLMGNLTCPTPPPTGKNINGPIAMSRERSNDSILSTNSSGTAGVWNIPAPAPRNPSALSGSLFGAAGSATAARMKIKTDSPLFDIDDDVESRETEELLASKDPESDIPPTTGNPSRPMASSVPISVTRPSFMIRGRSDDSDAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZ05</accession>
    <name>A0A9P6MZ05_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">THUMP domain-containing protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">THUMPD3</name>
        <name evidence="2" type="ORF">BGZ80_006671</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000330">
        <property type="protein sequence ID" value="KAG0018834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZ05"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043527">
        <property type="term" value="C:tRNA methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016423">
        <property type="term" value="F:tRNA (guanine) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000241">
        <property type="entry name" value="RlmKL-like_Mtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14911">
        <property type="entry name" value="THUMP DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14911:SF13">
        <property type="entry name" value="TRNA (GUANINE(6)-N2)-METHYLTRANSFERASE THUMP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01170">
        <property type="entry name" value="UPF0020"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribosomal RNA large subunit methyltransferase K/L-like methyltransferase" evidence="1">
        <location>
            <begin position="324"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal RNA large subunit methyltransferase K/L-like methyltransferase" evidence="1">
        <location>
            <begin position="434"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0018834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="530" mass="58195" checksum="8D9AA8E07789FE32" modified="2023-09-13" version="1">MHSSILQAYHDSAGAMNITANPQQEHQSQLKEEKSIQLFLSVPGGLEDVVVCKLPTLLVEAAGKISYRIGSGYLTVNFFVNEESFRASNTTVVTRVIADLVQHPPPCIFAAYVSIGTIAIPRKIFDSSKDLLVYVLGGFRRLQQQEQCGKENDTCSDEPAADLGLSWHEGLSVLGSTPSPLAKRLNLSISRSGQDPGNLSGVPSMRFRASFDRGDVQHKGVRSQDIAAGLGGVTGKVFSSWSVDLKDYDIEVMGRWIQEDLEEVDFKLESPEPASGDNSDGSGVQCPLECSSNKTSEQGCMPEEIKMQVGMTLPLALSTCPYRFRPMDGRTSLKIEIAYSLLAMANPKPGNVVLDMCSGVGTIPIVGAAHYPECHFTGLEVVPFNVEKAGENSKAMIERVNQERLKSGRCDSISSSPMTKEDPLARCPCLLVGDARAVCWRSKSIDLIISDLPWGQRESSHLSNCKLYPKLVKEIIRLLKVNGRALLVTGERRLLQRQLDSPFAKPHLKLLQKREITIGFKVMVFELERV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZ18</accession>
    <name>A0A9P6MZ18_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Chitin deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">CDA2_6</name>
        <name evidence="8" type="ORF">BGZ80_007104</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000358">
        <property type="protein sequence ID" value="KAG0018493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZ18"/>
    <dbReference type="OrthoDB" id="407355at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471">
        <property type="entry name" value="CHITIN DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471:SF2">
        <property type="entry name" value="CHITIN DEACETYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040235285" evidence="6">
        <location>
            <begin position="25"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="NodB homology" evidence="7">
        <location>
            <begin position="38"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0018493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="243" mass="26795" checksum="A67426D49EA85F30" modified="2023-09-13" version="1">MKVSAILSSTALLFLAFVASTVSAAPQSLGITKCKNPGVVAYTFDDGPGIYNDELLAKLASYNVTATFFVLGQMVEEHPDALKNILAHGHQIASHTYDHPNLDALSTSQILKQMTTTQDLIFQHAGVRPRYMRAPMGNCASTCQKIMSSLDMLVTYWSVDTNDWKYITEAQTDLQGALQNAMTEVNEEIVNNSNPATDSFVILEHEIHQYSVEHLVDLVFDAVSKKGYRFVSVAECYGESAYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZA0</accession>
    <name>A0A9P6MZA0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">2-dehydropantoate 2-reductase</fullName>
            <ecNumber evidence="4">1.1.1.169</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Ketopantoate reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_007743</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(R)-pantoate + NADP(+) = 2-dehydropantoate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16233"/>
            <dbReference type="ChEBI" id="CHEBI:11561"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15980"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.169"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the ketopantoate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.169" evidence="4"/>
    <dbReference type="EMBL" id="JAAAID010000401">
        <property type="protein sequence ID" value="KAG0017951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZA0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008677">
        <property type="term" value="F:2-dehydropantoate 2-reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1040.10:FF:000017">
        <property type="entry name" value="2-dehydropantoate 2-reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003710">
        <property type="entry name" value="ApbA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013752">
        <property type="entry name" value="KPA_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051402">
        <property type="entry name" value="KPR-Related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013332">
        <property type="entry name" value="KPR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00745">
        <property type="entry name" value="apbA_panE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21708:SF26">
        <property type="entry name" value="2-DEHYDROPANTOATE 2-REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21708">
        <property type="entry name" value="PROBABLE 2-DEHYDROPANTOATE 2-REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02558">
        <property type="entry name" value="ApbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08546">
        <property type="entry name" value="ApbA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0521">NADP</keyword>
    <keyword evidence="3 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketopantoate reductase N-terminal" evidence="5">
        <location>
            <begin position="9"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="Ketopantoate reductase C-terminal" evidence="6">
        <location>
            <begin position="193"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0017951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="326" mass="35768" checksum="4C5C3688F230F807" modified="2023-09-13" version="1">MGSPSPTRILTVGTGAIGAYYTWRLQQAGNCVVTTVCRSNYEVVSSKGIEFITTAWGEGPHIFKPDHVVKTVPSETYDFIVVCMKVLPHVYSIPDIIAPAVKASPNASIVLIQNGIGIEDPIKARFPRNPILSSIAYIGVTQNEPGIIYHSGTVHRLAVGLFEPIEGVDGNSALEAFGDICKQGGIETIVTDDIASYRWRKLIWNAAMAPICILSDLWTVSDVFANEKYYEVVLTVKSEIAALAIALGYSIPPGAVEMSMATSKKLADGYKASMVIDLEEGRPMEVEVILTNPIKVAEEHNLTHLIPTWYQLYKDLLKYLEVRQKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZF4</accession>
    <name>A0A9P6MZF4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S30</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_007588</name>
        <name evidence="7" type="ORF">BGZ80_009339</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS30 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000391">
        <property type="protein sequence ID" value="KAG0018076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JAAAID010000055">
        <property type="protein sequence ID" value="KAG0023472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZF4"/>
    <dbReference type="OrthoDB" id="2389564at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006846">
        <property type="entry name" value="Ribosomal_eS30"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12650">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S30/UBIQUITIN-LIKE PROTEIN FUBI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12650:SF15">
        <property type="entry name" value="RIBOSOMAL PROTEIN S30, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04758">
        <property type="entry name" value="Ribosomal_S30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="25"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0018076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0023472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="66" mass="7379" checksum="F264DD513B6EFABC" modified="2023-09-13" version="1">MGKVHGSLARAGKVKSQTPKVAKQEKKKKLTGRAKKRDTYKRRFVNVTNAPGGKRRMNVNPESSKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZL9</accession>
    <name>A0A9P6MZL9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dienelactone hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000260">
        <property type="protein sequence ID" value="KAG0019804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZL9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47668:SF1">
        <property type="entry name" value="DIENELACTONE HYDROLASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47668">
        <property type="entry name" value="DIENELACTONE HYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G01940)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dienelactone hydrolase" evidence="1">
        <location>
            <begin position="37"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0019804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="255" mass="28124" checksum="2B03AE3AEF62B23B" modified="2023-09-13" version="1">MILVNACCNTPPTDAQWQPKGQEKVLLVANGEERKVYRTGPKDSKRGIVAIYDIFGYHPTSIQFFDRIATSNGGFQVAVPEIFKELMPLSITGDMPAMLAWLREHGDYKKSNMIELIMAAVEDLRADGCTTFSILGQCWGTYIALQAASEDGTPFLAVGGPHPSVTNIETVKNVKCPLILLPSKDEADMIPVLESIKHKNFPVESFHKRFTNMHHGWTGGRGDWTDPEQLKAGVEAADLLGQYFAKVAEVSEGKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZS7</accession>
    <name>A0A9P6MZS7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Glutathione synthetase</fullName>
            <shortName evidence="10">GSH-S</shortName>
            <ecNumber evidence="10">6.3.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BGZ80_005048</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>gamma-L-glutamyl-L-cysteine + glycine + ATP = glutathione + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13557"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58173"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10 12">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="10 12">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the eukaryotic GSH synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.3" evidence="10"/>
    <dbReference type="EMBL" id="JAAAID010000251">
        <property type="protein sequence ID" value="KAG0019936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZS7"/>
    <dbReference type="OrthoDB" id="2020073at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043295">
        <property type="term" value="F:glutathione binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004363">
        <property type="term" value="F:glutathione synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.50:FF:000002">
        <property type="entry name" value="Glutathione synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1760:FF:000001">
        <property type="entry name" value="Glutathione synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1760">
        <property type="entry name" value="Glutathione synthase, substrate-binding domain superfamily, eukaryotic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1080.10">
        <property type="entry name" value="Glutathione Synthetase, Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005615">
        <property type="entry name" value="Glutathione_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014042">
        <property type="entry name" value="Glutathione_synthase_a-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014709">
        <property type="entry name" value="Glutathione_synthase_C_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014049">
        <property type="entry name" value="Glutathione_synthase_N_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037013">
        <property type="entry name" value="GSH-S_sub-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004887">
        <property type="entry name" value="GSH_synth_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01986">
        <property type="entry name" value="glut_syn_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11130">
        <property type="entry name" value="GLUTATHIONE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11130:SF0">
        <property type="entry name" value="GLUTATHIONE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03917">
        <property type="entry name" value="GSH_synth_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03199">
        <property type="entry name" value="GSH_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001558">
        <property type="entry name" value="GSHase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0317">Glutathione biosynthesis</keyword>
    <keyword evidence="4 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="9 10 12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 10 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutathione synthase substrate-binding" evidence="14">
        <location>
            <begin position="213"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="153"/>
            <end position="156"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="222"/>
            <end position="224"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="277"/>
            <end position="280"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="316"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="374"/>
            <end position="383"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="378"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="385"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="407"/>
            <end position="410"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="433"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="458"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="460"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="466"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="469"/>
            <end position="470"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR001558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR001558-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR001558-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR001558-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF03199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0019936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="482" mass="52916" checksum="64E536FB9DF59832" modified="2023-09-13" version="1">MSDLASTLTEDQLQILKDTALDFALSHGLVVRPPANDTNSAATFGGVINAPVSIFPTPFPINAFNDAVKIQPLYNQLVHDIAQDDAFLKEIMESLSTVDDFVKRLYDLYITVKQEGIAQPASLGIHRSDYIIHLNPGQDFSEAKIKQVELNTISVSFGSLSSLTGDLHKYLHATTGYFTDKIDDSALPVSESITSIASGLASAHQLYGSKTAKVMMVVQPGERNAFDQRWIEYNLLKNHGVVLIRKTLAEIADQGRLDPKTKALYIGDQEISVAYYRSAYATTDYPTEKEWDGRLLAERSLAIKCPTIAYQLVGAKKVQQVLATPGQLERFVKDPEAAAQLRASFTGLYPLDSSPEGMAAYEAALVNSDELVMKPQREGGGNNIYGKDIQTELRKLSAEQRNAYILMDIIRPPITKNVLLRKGELQRADVVSELGIYGIYLHDGRKEIRNDNGGHLLRTKGVESNEGGVAAGFAVIDSLLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0Y2</accession>
    <name>A0A9P6N0Y2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Plasma membrane channel protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_002971</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000176">
        <property type="protein sequence ID" value="KAG0021147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0Y2"/>
    <dbReference type="OrthoDB" id="296386at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032541">
        <property type="term" value="C:cortical endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005254">
        <property type="term" value="F:chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007632">
        <property type="entry name" value="Anoctamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049456">
        <property type="entry name" value="Anoctamin_N_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049452">
        <property type="entry name" value="Anoctamin_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12308">
        <property type="entry name" value="ANOCTAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12308:SF73">
        <property type="entry name" value="ANOCTAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04547">
        <property type="entry name" value="Anoctamin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20877">
        <property type="entry name" value="Anoctamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="314"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="392"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="430"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="486"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="617"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="domain" description="Anoctamin alpha-beta plait" evidence="8">
        <location>
            <begin position="108"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="Anoctamin transmembrane" evidence="7">
        <location>
            <begin position="280"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="75"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="38"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0021147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="838" mass="95194" checksum="2E22D84B67FA3862" modified="2023-09-13" version="1">MKNPSGNGQNNGHNKGNSDTKYNSLRGRNPKQPLQKQGSITSITSTGSNDHHPHKDLHFYDIHEASLHRVSAEVHTHPYQKSLSKRRRKKKAGQEPPPPPPKSLDVYADLVIVFKYHHTIGKWGVLEKLKLEKETLDAYEDVLTKLTDVGLQYETRPNGKDMILIFVLCPWSTLKREVDRDSLHDWLTGVKVADMGETEQLLKSTKERDNSLDNLTDSVRIRLIHDLITNDPREGGAGIFPGEDEFVESVMPLQDWEFNKSWLTSWSTKWFINHEDLCRIRDHFGEKVAYYFEFLEFYFISLMIPTGLGVFVHFFGSSFSIFYSISIIVWAVVYIESWKRRERELALWWGVSNVTKSEARRHGFKGDAYIKDPITDEETPFFSPWKRWARRIAGVPVILVGALALSILVTFMFGVEVFLEVYYDGHMKEILVYLPTVLYTLAMPYVENTCNNVAKWLTDYENHETEGSHDYHFVQKVFIFKVLNSYLSILLTAFVYIPFGPSVIPILQAYGLPFGSVAIEPKMLKDRLQAFMISNQVISFFTETIFPWATRKLMVGAHKIQKEVAEVLHHEEHNSEEEGFGGQDPAEVKRFLSNVASQVELPVYDVNEDYGEMIDQFGYITLFSVIWPLTGLCAFINNWIELRSDAAKICFHVRRPIPSRTDSIGPWLNNLEHLTWFSSLTNASILYLFREVMVHHAEAISSSAPTTIGLVASEIGSRFSFGMLLMCLLASEHCYLGLRWVVKTILESIPTQAELNVRKTEYGVKRSWIARLNGDTESVSGTRNSAAKKTSLSAIAALSMGAGMAMFPGSMSGSQVNVSSFLDDDPGAQAIRSVFKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N176</accession>
    <name>A0A9P6N176_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">L-serine dehydratase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_004694</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000237">
        <property type="protein sequence ID" value="KAG0020143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N176"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003941">
        <property type="term" value="F:L-serine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.90:FF:000001">
        <property type="entry name" value="L-serine ammonia-lyase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.90">
        <property type="entry name" value="D-3-phosphoglycerate dehydrogenase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029009">
        <property type="entry name" value="ASB_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051318">
        <property type="entry name" value="Fe-S_L-Ser"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004644">
        <property type="entry name" value="Fe-S_L-Ser_mono"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005130">
        <property type="entry name" value="Ser_deHydtase-like_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005131">
        <property type="entry name" value="Ser_deHydtase_bsu"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00720">
        <property type="entry name" value="sda_mono"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30182">
        <property type="entry name" value="L-SERINE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30182:SF1">
        <property type="entry name" value="L-SERINE DEHYDRATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03313">
        <property type="entry name" value="SDH_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03315">
        <property type="entry name" value="SDH_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143548">
        <property type="entry name" value="Serine metabolism enzymes domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine dehydratase beta chain" evidence="10">
        <location>
            <begin position="116"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="Serine dehydratase-like alpha subunit" evidence="9">
        <location>
            <begin position="323"/>
            <end position="629"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0020143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="636" mass="69041" checksum="1B75F16D3608E448" modified="2023-09-13" version="1">MSTFSRARLAIPRQVRLYTNTYQVQGITTTPIPTTATTTARAAAVATRPFRPLTSSHLQTRTRLFTLAKAVQSSFFSTSARCNDPALTTPVPTPVAPEQAVHQGRPEEETVHAVVSTFDLFSIGIGPSSSHTVGPMRAAKIFVTDLKDHDVLEKVASLRIDLFGSLALTGIGHGTPDSILMGMEGESPETVETTTIQSRLKAIDEQKALTVNSTNRIRFDPSKDLVFHYFESLPQHPNGMRFCAFDDKGDLLATNEYFSIGGGFVVNERTQLAHGENVFYKGEQDKETKANKPVPQTRRSQDLATAALPFTNATELLELCQRENMTIAQVVLENELRWRSMEEIKEKTFAIWNTMDNAIKNGCLSTDEMLPGRLRVRRRAPGLYKKLLKGLYSTTPLYKDSTVSIGKSSLLGGGNGLTNQIPERGIDRVLPKRAVKRLMLPALDYLSVYAIAVNEENAAGGRVVTAPTNGAAGVIPAVLKYYLEFISDNPEQDIMEFILTTAAIGMLYKRGASISAAEMGCQGEVGVACSMASAGFAAVMGGTVQQVENAAEIGMEHNLGLTCDPIDGLVQIPCIERNALGAVKAVTAAQLALNGDGHHRVTLDQVIETMRQTGNDMQAKYKETSQGGLRVCVPVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N249</accession>
    <name>A0A9P6N249_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ADP-ribosylation factor-like protein 8B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ARL8B_1</name>
        <name evidence="7" type="ORF">BGZ80_003185</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the small GTPase superfamily. Arf family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000183">
        <property type="protein sequence ID" value="KAG0021023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N249"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04159">
        <property type="entry name" value="Arl10_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001120">
        <property type="entry name" value="ADP-ribosylation factor family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044154">
        <property type="entry name" value="Arl8a/8b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45732">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45732:SF7">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00328">
        <property type="entry name" value="SAR1GTPBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="7"/>
            <end position="14"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="110"/>
            <end position="113"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0021023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="164" mass="18200" checksum="C07529F889AA0869" modified="2023-09-13" version="1">MELTLVGLQNSGKTTLVNVIASGQFSEDMIPTVGFNMRKVTKGNVTMKLWDIGGQPRFRSMWERYCRGVNAIVFVIDAADHDKLDAARTELRNLLDKPQLASIPVLVLGNKNDLPGALTVDQIIEVMNLKQIASREVSCYSISAKNQVNIDITLQWLIKKGKGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N281</accession>
    <name>A0A9P6N281_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cell division control protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">CDC10_2</name>
        <name evidence="6" type="ORF">BGZ80_003186</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000183">
        <property type="protein sequence ID" value="KAG0021024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N281"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032156">
        <property type="term" value="C:septin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01850">
        <property type="entry name" value="CDC_Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030379">
        <property type="entry name" value="G_SEPTIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016491">
        <property type="entry name" value="Septin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18884">
        <property type="entry name" value="SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00735">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006698">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51719">
        <property type="entry name" value="G_SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Septin-type G" evidence="5">
        <location>
            <begin position="1"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="298"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0021024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="389" mass="44435" checksum="CE72DCCB2055AF4D" modified="2023-09-13" version="1">MVVGESGLGKTTFMNTLFNADLKEEIPTKKLHSTQTVQIQPSYYELIEDGVLLNLCIVDTPGFGDELNRERNLTPIIEYIDQQYAEYMKAERQPGFRKSIPDTRVHAVLYFLAPTGHGLKELDVKALRTLSQKVNVIPVIAKADTMTAEEKIAFKSLLLRDFEEYRIDTFPSSHLDEVDGAEELLVGHTNGNMSHSQLLEAKALQSLEAEECVPALIVGASLKGSPTGSFQDLNINGNFISIVENAEHSDFIYLRELLLETCLHDLVESTHRVHYHDYRAKALRTNNRVSFYECDESYDSHLENSKKAKADMERREEEIRQKFIEKVHETELALREREEQLMAKKMEMVAELDQYKALLEAEIREVDELEAISRNNTMSKNSSKSFRSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2D8</accession>
    <name>A0A9P6N2D8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CipC protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_011432</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000092">
        <property type="protein sequence ID" value="KAG0022697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N2D8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022234">
        <property type="entry name" value="DUF3759"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37450">
        <property type="entry name" value="CIPC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37450:SF1">
        <property type="entry name" value="CIPC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12585">
        <property type="entry name" value="DUF3759"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0022697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="100" mass="11134" checksum="D17DC8FEC77D670F" modified="2023-09-13" version="1">MSKFFESFNQVNDSPHKAELSHELIAAAASYEAAKAYEKHVEKNGKPDSHAKAKEIFAALAGAAVDRLIETKGLDFIDKEKAKHQAKKHTEDIYVEEFSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2N4</accession>
    <name>A0A9P6N2N4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycoside hydrolase subgroup catalytic core</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_002438</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000160">
        <property type="protein sequence ID" value="KAG0021420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N2N4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0021420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="493" mass="54090" checksum="B4FE075122B50DE8" modified="2023-09-13" version="1">MTNAGTWCGKSYSEPTNQQPSVSNSGVFAALPPWPPADALAVTPRWKPIYETDDSVEFVVDVPSDIIETNIIFYFGAGKTHETHVHPGINVIAVPKAKVGVTSTVTALLGSARANATFTIYKRPSPGTQIVVRVDYMHGSLVQETTRAAAAAVTPVFPFGMYVEYEPFTVKDPVGAMKELRDMGINFINIVPPYDARLKAVLEAAKDHGIWVQYDMRHTYVSAVNITAEINDVKSYESIFSWYTSDEPDGELTASEPRNSINAYNTVNSIDPHRPTMLALNCMRNSAGQYANAADILMTDVYPIGISTKACNAEIGCCGCDECIGDFAIDIRHRMHSYRSQLAQVGKPRMPIWMVTQAFSDPNTYWSREATPSEFRLISYISLIHGAKGVLSWIYPGNMSPKLRAIIPTLSAELVPLGSKFILGGKQIVEYSDGKITAGAWIKDNAKLFVVTNPTYRQVTLTNAQIKAIFGDDYKLIKAGETLPALAIRIITA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N399</accession>
    <name>A0A9P6N399_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glutathione peroxidase gpx1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">GPX1_1</name>
        <name evidence="4" type="ORF">BGZ80_001447</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glutathione peroxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000133">
        <property type="protein sequence ID" value="KAG0021906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N399"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000889">
        <property type="entry name" value="Glutathione_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11592">
        <property type="entry name" value="GLUTATHIONE PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11592:SF78">
        <property type="entry name" value="GLUTATHIONE PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00255">
        <property type="entry name" value="GSHPx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51355">
        <property type="entry name" value="GLUTATHIONE_PEROXID_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 4" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0021906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="90" mass="10259" checksum="D6B9837A47187697" modified="2023-09-13" version="1" fragment="single">EPGSNEEIESFCSINFGVTFPMMDKVNVNGDNEDPVYAYLKSQKKSLMMSRIKWNFEKFLIAKDGTVYERYASTTTPEHIAKDVEKLLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3J2</accession>
    <name>A0A9P6N3J2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_009810</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000062">
        <property type="protein sequence ID" value="KAG0023316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3J2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="228"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0023316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="268" mass="27752" checksum="8DAF0485A9B4805E" modified="2023-09-13" version="1" fragment="single">KTAEEEAARVAAEAKAAEEEVARKAEEAKKVAEEEAARVAAEAKAAEEKAAAEAKAAEEEAARLAGEAKAAEEEAGRVAEEAKKAAEDEAARVAAEAKAAEEKAVAEAKAAEEEAARAAAEVKKAAEEEAARIAAEAKAAEEEAAAAHRRAEEEVARIEAEAKKLAEEKVEDVKEAVEDDSAKVAAALVAAEEASSSAVADAVKKVEAPEVTAIPSLKPTDEIKTAPLTTTVVPSDTTASVTSVNSKKDKKDKKDKKKAKGEKSCIIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3K3</accession>
    <name>A0A9P6N3K3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">60S ribosomal protein L26B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RPL26B_2</name>
        <name evidence="6" type="ORF">BGZ80_011178</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000087">
        <property type="protein sequence ID" value="KAG0022768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3K3"/>
    <dbReference type="OrthoDB" id="1688503at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06089">
        <property type="entry name" value="KOW_RPL26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.30:FF:000009">
        <property type="entry name" value="60S ribosomal protein L26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01326_A">
        <property type="entry name" value="Ribosomal_uL24_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005825">
        <property type="entry name" value="Ribosomal_uL24_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005756">
        <property type="entry name" value="Ribosomal_uL24_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041988">
        <property type="entry name" value="Ribosomal_uL24_KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01080">
        <property type="entry name" value="rplX_A_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11143">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L26 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16906">
        <property type="entry name" value="Ribosomal_L26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01108">
        <property type="entry name" value="RIBOSOMAL_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="KOW" evidence="5">
        <location>
            <begin position="48"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="36"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0022768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="132" mass="15182" checksum="7D5701930F8E1CAA" modified="2023-09-13" version="1">MKQSVDVSSSRRKSRKAHFSAPSDLRRKIMSASLSKDLREKHSARSIPIRKDDEVMVVRGSFKGREGKVVQVYRRKWVIHIERVNREKANGASVPVGIHPSKVVVTKLHMDKDRKAILERKDRSKKAEAKQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3L3</accession>
    <name>A0A9P6N3L3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_009525</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000058">
        <property type="protein sequence ID" value="KAG0023401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3L3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="360"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="609"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="101"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="124"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="254"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="281"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="320"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="377"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="407"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="436"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="460"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="475"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="490"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="506"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="548"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="619"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="656"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="668"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="679"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="738"/>
            <end position="747"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0023401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="817" mass="88725" checksum="516C326023645D3F" modified="2023-09-13" version="1">MDRGYTTTYDGDNQRYSSSNHRQQGYNNYRNSNYQTRYNREDGSAENTNNYRGNSSRGNNYNNSTTKNDFYPYQHQDNQPRYGSGSQGQRRDSYGDNRAYANKPSNINSSNPAASLEAHQQGRSSDSYASGVRSSASSFHETYDKLERTESLADRYAGIEIKVAVVKTYREMATQTTEDVLPDIFSPHESTWNGVRITTVDRSQQQNAKRGSSFTTPEPSVTSSLLKAISTPPTPSRFERSASEQQGYKHQEDNQTLAPSSQSWGDPPKTPAAQAGQGMISPSSSSTDFLSPPWENSNSKPASQPKSSAPAVDPWAAPFTSSSTNVSSSPGGGGSGVATVGWGDQDAKKKGIAEMVDWSKGVFEFPDAKPTKMVVSSGWSARNTTNDTIPETNPQQSHDIAQSQHAVDNENSDRDLSASRDPWSSGGDRGGSSYGSERRPAPSQDPGDRRHSQYRDDTQVQELNSSFNSHGDYINRSASNSNSGSNDMYRQSEDRKPMSSEDRFCNSMNRRTNANDSYSSYNTGSNDSGAGDYQNRNQPQTQHHRDGSTATASSLSSPPGRRGLGNTGAQNPAIAGWSAASRLAAPGKTYNGGSGLATASDFMSFMQAAGSFPTSGRKSNTTGGSRNGSSVEGGSVRDESINGSRPGSPTGRGREQSITNLDQSRGQSQDRLRSDPQQDHQILQPLTETHQKEPAIAIQGDQTTDAAAMVPLWSTTGSDFELDWSKQVERQEEEEDQMANNGSISNNIEDRQQPTEEPLIPGLADTPERPATPLNVEPESVPLPISRTSSHEDSNSQPATVTADEDNLFSLQDQSQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N465</accession>
    <name>A0A9P6N465_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF7492 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_002057</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000015">
        <property type="protein sequence ID" value="KAG0024497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N465"/>
    <dbReference type="OrthoDB" id="64281at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055915">
        <property type="entry name" value="DUF7492"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35559">
        <property type="entry name" value="CHITIN-BINDING TYPE-4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35559:SF1">
        <property type="entry name" value="CHITIN-BINDING TYPE-4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24320">
        <property type="entry name" value="DUF7492"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040466929" description="DUF7492 domain-containing protein" evidence="2">
        <location>
            <begin position="34"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7492" evidence="3">
        <location>
            <begin position="31"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7492" evidence="3">
        <location>
            <begin position="163"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0024497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="244" mass="26559" checksum="9B639246743BB383" modified="2023-09-13" version="1">MPNFASTASSATLLFCLFFVLGSSFIQVTTVQAHSWLDCANTLPSGKCAGYPIGYPTRANPDINTLYTYLISGRVNTTAVCQPGRQDIFPGKNPANLPPTTAVPGQKLHLTWEANGHMNNVQSSSEPRTKVQVYWTGVPKKLIHTRAELSNPKLLLATMDFATPQNCDEPANPNTVCNGYITIPKGTKPGKYQLVWWWRFDKNPVGEEYSTCFEVDVKTASKTSSKAASKTSSKAASKTSSKAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N492</accession>
    <name>A0A9P6N492_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">WD repeat-containing protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">WDR6</name>
        <name evidence="9" type="ORF">BGZ80_009802</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the WD repeat WDR6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000062">
        <property type="protein sequence ID" value="KAG0023308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N492"/>
    <dbReference type="OrthoDB" id="5594999at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051973">
        <property type="entry name" value="tRNA_Anticodon_Mtase-Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14344">
        <property type="entry name" value="WD REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14344:SF3">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="3 7" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="247"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="652"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="657"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="679"/>
            <end position="689"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0023308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1183" mass="131307" checksum="A74623B1B5706C2A" modified="2023-09-13" version="1">MDERKVRTRPVHLTTPVTALAYHDDEILLSGQGPYLKASLISTSETLKCIHLGGDWKVHRIVQANIQHISDSTVTRLLLVFGAKSLRIMRLVVTRSDGKSHPSAYFQHLWNVPHMKDWILDAQWLWPKSDIPGESPALRSSKGVHITVPPTSIAIGYAHNFVEVFDLPQDPFTISHQENELLQEDSLPNFQLTYSVQSEEHCTLFCGRFHNNTLEDLWFASGTVFCHALLWKVHHKGGIEAPVVNSLIGHEGILFGIRWSDDGKAVCTVSDDRTIRVWDITHGTNITHTTHFGHTARVWDCQFAGQYLISISEDASCRVWRNPLLPGSDDTDDMSDCLACWEGHEGKSAWSVAVSSHGVVATGGGDGGIHLWRLDSIVAGSSDAEQNTRDINLPDITTYYPEAVANEKEFVRDFVITSHSQSIYATNTGYILVRDDNNGAWSTLYNSPLLKNYVSLESSACGRVVVAGCLSGKLAIVSVQNEFETIVADTIGGIKIQFIFLLEGESLDDFRIVIFRANCTVGVFHLNISTATSKATCDHICDLKLPKNNKAIHAAYYSPLYNLVLLGSRDGAVMVYNLDQVVKGLSEPVTLESIVILERCHGNDSVSSILMITERGEGYEGRDRINVYTTGRDGSWAKYRFLGLPGGEVIGARSLSDDDDNSDIESDDDEGITNMPNEPDNHSNLDDREGGSTIVLQKVFRSKITKGWLEKIFIMDGELLLLGFFNKKLFVYNESKHFEIRSFSRELTAGSELFESAKLQNNFHGREVRHLRFLSGARPLTEGAPAPIIIATGGEDCRLRMFQYIPYKTKNSCTALKPLCNLKPHLGAAIRCLEWSHTEVPHSYVLFTGGAIESMRAWQVTMSIPNSYQVQAVEDHSGKVVQEHTPLFLGCFELAQCPHVSENLETRIMDLSVFRLESHPRMHFIASVYSDAAIRVWLFDEVTNTFVLAIDTSYHQKCILQVSHVRVGEGIMMLTAATDGKIAIWDLTSTLDKFLEKYDADENKVVKPHSPSYGKNKQKVQKRYAQRLDRPIAEVTAHMSGVNSLYVQNLGQDGILAVSGGDDNALAAVLIKATWNPSLRAIEAQSANVIARDDYAHGSAIQAVFMINASEIVTTSQDQMLSLWHLDRVGGNGYDAALVKLESQFVHVPDPSTMDILASEDKTKDSVIIAGIGVQIFDVDAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4J8</accession>
    <name>A0A9P6N4J8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003705</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000002">
        <property type="protein sequence ID" value="KAG0024846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N4J8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="732"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="859"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="733"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="747"/>
            <end position="765"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0024846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="879" mass="99378" checksum="C60C5F9679D98A78" modified="2023-09-13" version="1">MELLPPECLEMIIALLRYDLASLYRLLFVSRQFFQLTVPVLYKSPFRLAAGIPDPPPVSFYSSPFTTALPYRSATNSTDGWSRFLERTKLLSRLLIQNLQLDHLGQVPKLVVHEAVIWDDFGCSENLEPLIPPTDHLFKSTYSPTIEIPSDWSRSVEQSFAANTGTGFEEQEGWGVNQQDHSDGQYPDLISFDDEWGDSHQSTTKQDASVLENAHSSNEKSRSDSSRKTSGTGLLVDYFYFYTHHDHRSIASVIREIYPGAGRREYDRYLASIERAILMHNTRQIEVIHVHSPSVVVPHLHENLEKLERLSSIELFDSVWKGPELEMVHQFLMDHTAMFSGSRRLSGKEDAYTFDRYLEKMNDLDLGHGARRRHSPIRNIKYTTNRSFWDNTILTGKPFDPIQLIKALGPGLESIDSTYWPRTELADLETLDVRSLRSLKIGSQVTQYSDVAFSRPQFLSRCRQLQNLETFSNSKGMFKWAVEEWNVSKRARKDATLTSNDSHDPWTMGGTRAAAVKPLVQLRRIRIGGATDQIIYDILRDAFYGFRKTLQSIEARSDTESAEGEAEWMDHAQHLLSGSQATASTRADARDRVKECDSSKITAEQEEGYYNSLSSIASRLLLIRWEIPHLSVLSLSGSIASAFDIGSLQFMPSLHTACFKIVAPPSAWIARGQSFNMAGSLSKDSRSQIKRNMTHLPVVAPRTLRCVMIRGPWPEVTDESLQAMIETIVVPRSSDDGRKTHLHSSDDEGSDEDSYSDSDPDDNDDGSWGNQLLELSILDNDCVTVQGMIQLARQMDKLQIMGTTLNTFSRSSNADSRLHSAYSEDSYPAKEPYSTSDMTLNARDLILKAQIEMPWVDLGPDANHLGKRNKRGGYQSSYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4P5</accession>
    <name>A0A9P6N4P5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007558</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000039">
        <property type="protein sequence ID" value="KAG0023866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N4P5"/>
    <dbReference type="OrthoDB" id="2370938at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0023866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="305" mass="34170" checksum="6EE2F3D89CC7F6A5" modified="2023-09-13" version="1">MSTEPGTSWIQSTCGGSPRAFFEAFDIYVKQYGYQKYTQTIQESNLDMDTKLDLWQKFKYWKANDGVQFWLDRQSQSSQIITASTLVKGSESYAKESIHRTGKENTGDKDIESSMSSIVSQAENGKKWSLGTAFIENLQKTPRRRALSPTPQIPTISADSPNFIPVIRNEPNPLDDVDEDDFIIPDNTDNTYRISAILDGRDIGIGFRHLFQDYSIRCYPDFEGSDSPPAGLFRRIVGSFPTIREKAYKIGSVDATAVRNEVRSSAGRLDTFETTLLAFGETASQAVAKHSKDSLEVLKLTAKEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4Y9</accession>
    <name>A0A9P6N4Y9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_007130</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000036">
        <property type="protein sequence ID" value="KAG0023943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N4Y9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="38"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="246"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="83"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="172"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="44"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="251"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="265"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0023943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="296" mass="34184" checksum="995B958BF8776A40" modified="2023-09-13" version="1">MYHHIPELPSPPLSPLSPRDQASGGMVHAKSYSIFEDSSDCNSHNQHYLPQQQQHNQGRESKHQVLPDVVMSAEDWYQVQTHIGSLEKDISQVSRMNKLLNQELDNVNNQIQRLTSQKCEGSQNQYEFLVQQIDGLHRQLQLAHNQISYGGFGDNDVGYYKALRQGEQPDTTKQLQSEVKELAKSLKNWQIAFQQAEEKYKRKCEGERTLKQTLRKRETQLSSLIEKLNECEKSIVNHKELEALEAKKRSSVSSHVSTPTPDKITSVDHKMKADDNKRKPRILQEQHTEERHLEVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N526</accession>
    <name>A0A9P6N526_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Enhancer of mRNA-decapping protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">EDC3</name>
        <name evidence="9" type="ORF">BGZ80_008098</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">P-body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EDC3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000043">
        <property type="protein sequence ID" value="KAG0023771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N526"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031087">
        <property type="term" value="P:deadenylation-independent decapping of nuclear-transcribed mRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033962">
        <property type="term" value="P:P-body assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10260">
        <property type="entry name" value="YjeF N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025762">
        <property type="entry name" value="DFDF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019050">
        <property type="entry name" value="FDF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004443">
        <property type="entry name" value="YjeF_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036652">
        <property type="entry name" value="YjeF_N_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13612">
        <property type="entry name" value="ENHANCER OF MRNA-DECAPPING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13612:SF0">
        <property type="entry name" value="ENHANCER OF MRNA-DECAPPING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09532">
        <property type="entry name" value="FDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03853">
        <property type="entry name" value="YjeF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01199">
        <property type="entry name" value="FDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64153">
        <property type="entry name" value="YjeF N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51512">
        <property type="entry name" value="DFDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51385">
        <property type="entry name" value="YJEF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040159043" description="Enhancer of mRNA-decapping protein 3" evidence="6">
        <location>
            <begin position="18"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="domain" description="DFDF" evidence="8">
        <location>
            <begin position="292"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="YjeF N-terminal" evidence="7">
        <location>
            <begin position="479"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="116"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="165"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="345"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="425"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="174"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="217"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="243"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="270"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="387"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="429"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0023771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="724" mass="77932" checksum="65A01CE1572C4176" modified="2023-09-13" version="1">MASAFIGLSVKVLLTSGTSLKGHVADVDPITQRLMLQDVVIQYAEEKTVRVMSSFSVAGGEIKDLQVLPTQPASRMLHLDQNPSSPSSVSTPTMATATAARPHYPNQQEHTQAILNTPSPSQLPAHPHPATVAGPSSSNSMPFHDPAIISAGSSSLQYHDPAIISFKPSTSPAQHQQQQQQHQQHQQHQQQSYNGSDGLAKKMSTARISKPQHQNHDNLTMAESSATESVSRGPRRTRRSMQNNNTNNNYASNTNYNSNNNMSDYGSPRLSHKSISGKRASRKHKEPIHEWAQGDTDDFKDEDFDFQHNLGLFDKAAVFAEIREADDTAPESLLVNLNRNPNRARAMEESPMLRKLKPTENVLDPAPKRTTYKRTNSKNNVHGSGLSEEDEADESEDDDSWNGSVDESSVAVGAASGLKMRTNGAVGSGTLSSPSLPATATKANGEGNNSNSGGGSKKRAVKIQTLSGVACPTVTALQMQEVERLSASDMGLSEEQMIENGGRGAAMMCLQALGGSRRIQPNNHNSAPLVVILAGNNRTGAYALCAARHLSNHGCQVMAFIAGSNLEGQLHSTVASQSRGFLAAGGEMIHTITELPQATSPVDLIMDGMLGYQYTVRDIVDSDERETVCDLMDWANDNKAPVLSLDMPSGVNGTTGQGDKTKFCVRPKWTLCLGAPKAGCRSRSTTGELFLTDLGIPRACWKKAGVKGWGMPWGADFLVGLEYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N615</accession>
    <name>A0A9P6N615_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005480</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000027">
        <property type="protein sequence ID" value="KAG0024174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N615"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="513"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="517"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0024174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="640" mass="70431" checksum="4129BD779EB3EFE8" modified="2023-09-13" version="1">MEKLGHVRNNDQEMAAVDVDVDTDVDLDVDVDVDVDVDTEVDIASELVQGPAIFRLSPELLALIFHYVYVTPVVHRPTTLQNEHDATTPETTITTTETTETITTTTITSITETTTTETMTTTTTPGARRKKDKRKSAVYIQNDISSMLALCLTCRAFYPQAIRMLWRQRTLANYDELTEFYQAIDFSASLRKRQQKQRQIEQPLQRPGMGYAVEEGLFNNEAALRIKSLTLLDMSLGSTLPLGGVADATSTLASSQFFGGSGSGHSDPLSAGANFDLCQGIDMLTRTNAVGGDAAYTSFAKDTTTASSSSSSSSALNKRRFRQKTTSIYSEMISPRLLHTIANHCYALVDLTICMDNKLSVISDFPGPSTQPSIPLSIIAGALLSLKRLTLMGLNCDPQRNKTGSELLVFAQNAQPLERISIRSCKGISVETYIEFGVRSHSRLLSLDYQGLDFETSQQLTDMMSAYANHCKNIRSITLSCLNALSLDGMMEALAHHGATELQELHILGHDSVRTHQQQQQQQEAPAVQPQQQPQATLVQSYLPQTQGPEGVEENAFGPPATPAPLAPFTSAGFFGLIFDQCPWLKYMFMKVTLETAQEWIVQPCFKTAGLDKCLYQYRTATGTPAVVLMWDARKKAIKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SRK5</accession>
    <name>A0A9P6SRK5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Carrier domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_008028</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004231">
        <property type="protein sequence ID" value="KAF9993804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SRK5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043041">
        <property type="term" value="P:amino acid activation for nonribosomal peptide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.30:FF:000010">
        <property type="entry name" value="Enterobactin synthetase component F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1200.10:FF:000005">
        <property type="entry name" value="Nonribosomal peptide synthetase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF1">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="4">
        <location>
            <begin position="131"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9993804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="380" mass="42627" checksum="E153484999654626" modified="2023-09-13" version="1" fragment="single">MYKTGDLARYLPDGNLIYLGRNDHQVKIRGFRIELGEIEARLVEHPLVHEGVVVAIGEDSDKRLVSYVVSDAVDHLAQLLRDHLATVLPEYMIPAAFVQMDALPLTSNGKLNLRALPEPEREAFASQGYEAPRGEIETALADIWVDLLKIERVGRHDNFFMLGGHSLLAVRLMNRISTLGVSLQLSALFASPTLSELANVISNKFVKENHTFDPITPISRDGVLPLSFAQQRLWFLAQMEGVSDAYHIPMAIRLQGSLNRNAWQSALNTIFARHESLRSTFVNIDGQPQIRLLPAEKGVPMLIHDLRGELDIEVQLHELKSLEASAPFDLEKGPLIRSRLIQVADDEHVILLTQHHIVSDGWSMGLFTRELSELYTAYSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ST69</accession>
    <name>A0A9P6ST69_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Kelch repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_006573</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003253">
        <property type="protein sequence ID" value="KAF9999413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ST69"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9999413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="144" mass="15837" checksum="C2D0F6A08A6E385B" modified="2023-09-13" version="1" fragment="single">MSVSVDQNNLIFWGTNTGVSTYSIPNDNWSVISSSQPAGLPASAGKYSTGDPKTGEMYKLAVAQTGTPIFISYNTITNTTKTLSLPSDLTTRELRYYSMVWSTQRNSVLLFGGYFNTTNVNNATGLVNPSFYEYNPTTDIWTDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6STP7</accession>
    <name>A0A9P6STP7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006135</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003014">
        <property type="protein sequence ID" value="KAG0001700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6STP7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040409475" evidence="1">
        <location>
            <begin position="20"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0001700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="225" mass="23100" checksum="4CE9C4A7081E2B29" modified="2023-09-13" version="1">MKFNTVLFALSAVAAVASATVEVPSVPGVPGVDLTPAVEKRDVPGLGNAGDIAPAALKTIEDAIGGTGVAKRGLINIDANVTAYVKAIVAVFAKIEVEVIAEIVAALVVDLEKLEGLYPAYVKAYIDLHLYASIQAVIAAHVDVGILGLINIDVNAVASVCAEVVINVRVMIEAAIKLALSDVCKDFGIPDVLALAENPDNTIDGILAKDNLANQVKNAVNGISA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6STS3</accession>
    <name>A0A9P6STS3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Oligopeptide transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_006354</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003131">
        <property type="protein sequence ID" value="KAG0000514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6STS3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035673">
        <property type="term" value="F:oligopeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004648">
        <property type="entry name" value="Oligpept_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22601">
        <property type="entry name" value="ISP4 LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="55"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="120"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="152"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0000514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="177" mass="20003" checksum="54B34C0F2D67353A" modified="2023-09-13" version="1" fragment="single">MSDQKYEYSEKDLVEERFDIERSSVILEEEENSPIPEVAAIVSNTDDPTLPSLTFRFWVMGLGFSALISFCNQFFWFRENPITIGMSVVQLLAYPIGKFMAKVLPYGFLNPGPFNVKEHVLIALSANCAAGTAYAIDIIVIQKIFYNQDFGFLANFLLIITTQMLGFGMAGVLRRYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWN5</accession>
    <name>A0A9P6SWN5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ndc10 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003888</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002057">
        <property type="protein sequence ID" value="KAG0008072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWN5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.20">
        <property type="entry name" value="Centromere DNA-binding protein complex CBF3 subunit, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038279">
        <property type="entry name" value="Ndc10_dom2_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="230"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0008072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="378" mass="42933" checksum="6C83653DE0B97EB0" modified="2023-09-13" version="1">MHYKVLRGRVSPTKDISSQGQYDATKGLFLRHAINTSRVTHEGRHSGALEVERLGVAPVDIAAGVQWMVERDKMGIHYLSRLPVPCTKAMTGFKDRSFYLPWNRADLPLDLQRQILPWVESQIGTPGSPEREEWTIACIQEMNEVNEDDTESFERIETPKKINKDGYQTTSVVKRGFLELLVRCRRVILQAQDVQEMESLEDNRLRDIENIIPRIADEIRTTRGSIGVRQDTLLRDNSNQRQNMQEIERRLEFSERMLQYVSQQQMLRHMSQEAKDSRQQMADIQQQMGDIQQKILTDSSPTWATAATTKTAVRTVNTVNNNKWGGWTATGITSTGASANSPTNYKHFESIIIAPSSTRTDKIDTLPPAATSFPGSTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWR0</accession>
    <name>A0A9P6SWR0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_003330</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001875">
        <property type="protein sequence ID" value="KAG0008538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWR0"/>
    <dbReference type="OrthoDB" id="205514at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.110">
        <property type="entry name" value="DNA polymerase beta, N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027421">
        <property type="entry name" value="DNA_pol_lamdba_lyase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022312">
        <property type="entry name" value="DNA_pol_X"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010996">
        <property type="entry name" value="HHH_MUS81"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11276:SF28">
        <property type="entry name" value="DNA POLYMERASE LAMBDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11276">
        <property type="entry name" value="DNA POLYMERASE TYPE-X FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14716">
        <property type="entry name" value="HHH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47802">
        <property type="entry name" value="DNA polymerase beta, N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="4">
        <location>
            <begin position="601"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="74"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="337"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="504"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="86"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="165"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="196"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="241"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="272"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="349"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="359"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="394"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="514"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; Schiff-base intermediate with DNA; for 5'-dRP lyase activity" evidence="1">
        <location>
            <position position="727"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="769"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR622312-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0008538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="769" mass="84423" checksum="CF0BA0D017786B97" modified="2023-09-13" version="1" fragment="single">MASSHPYAASRESKKSRELISTFGLPCPPKCAAPQDNKSFFDHMDSIEKALEEEDAGKLPKTLEAGPEIIVESLNKKRRRVQTTEAPVVVAPHPHPASSSPPSSPPSAQPLGPFPSISPDTLPVSEKAPENNEATASQPPTKKARLQKETEHHSTKPRPSSPIRRSSRLASIRRRSSSYAGHAIGNAAELPPLPLSPSISQQMTTDTTDGQTPTMQAGPEIVVESLNKERRHSQITETPPVVVPQLPPVVAPQLPPVVAPQFPPVVAPHPHPVSSSSLSSSSSTQPLDSFSSVSPDTLPVSEKAPESNEVAASQPKLSPLKLSRVHAWEMFYQEDDEKKLQDRLSGRTLPPPLCPSIPHPHAASSPSLSSSSSAQPPDSFSSVSPDTLPVSQKAPESNEVTASQPPTKNVRFREEIEYRFIESRPLPSIQGSSRLASVRHRSSSRAGHAIGNVAELSPPMSSRIFTPGMLCPEDDEKNFQDWMSGRAPPPPLPPSISRILMKRKKTQETEPLADSQTSNARNQGSQVRVGESDGASNSNNKDIIGIAPISDTASFAKPNATPNTNHTPKPLTRLPIQLWLSDDNRLELTPKMKIELAHESRCFRCKEVGHWVNRCPQPKPKPKDDEVLLQIINSEKSKGKRRKILYQCQPPHVVGKNEEPKYNRAFLEQLKILMDHYENIKTKDSKEHFKVINYRKAITAIRSLDYGITSEEMALKVPRVGKKIAQKIGECIALGKIKKLEHINWDKERSEVETLFQSVHGVGSEKATE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXG0</accession>
    <name>A0A9P6SXG0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001912</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001454">
        <property type="protein sequence ID" value="KAG0009940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXG0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0009940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="57" mass="5928" checksum="5391296E0DEEB36D" modified="2023-09-13" version="1" fragment="single">VSSVALPAAPPITPPITPPARSKQRKRQAPAAAKSDNSDKLNKRGKGNGHVFTPSRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXZ1</accession>
    <name>A0A9P6SXZ1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001137</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001255">
        <property type="protein sequence ID" value="KAG0010850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXZ1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="23"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="170"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0010850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="179" mass="18469" checksum="3751D9207A346C17" modified="2023-09-13" version="1">MSTRTTTVRASQTTTKSKQDNASTTQQDTQQPSQDRCAHCKKHPETHSPTGCAQKAREQTRQQFQRDSGHILGAESHDRGSTHRPGWNIEASRQDLHQRLNQRVQSLKESSGRTPSAQNPGSGSGSGSGAGAGAVGGGGGAKKGKGSAKKTANKPKTWGSGGSRLGGVPGSAPSSGPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXZ2</accession>
    <name>A0A9P6SXZ2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">protein-disulfide reductase</fullName>
            <ecNumber evidence="1">1.8.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">NXNL2</name>
        <name evidence="9" type="ORF">BGZ80_001097</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>[protein]-dithiol + NAD(+) = [protein]-disulfide + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18749"/>
            <dbReference type="Rhea" id="RHEA-COMP:10593"/>
            <dbReference type="Rhea" id="RHEA-COMP:10594"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.8.1.8"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>[protein]-dithiol + NADP(+) = [protein]-disulfide + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18753"/>
            <dbReference type="Rhea" id="RHEA-COMP:10593"/>
            <dbReference type="Rhea" id="RHEA-COMP:10594"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.8.1.8"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.8" evidence="1"/>
    <dbReference type="EMBL" id="JAAAID010001245">
        <property type="protein sequence ID" value="KAG0010905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXZ2"/>
    <dbReference type="OrthoDB" id="409136at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047134">
        <property type="term" value="F:protein-disulfide reductase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052259">
        <property type="entry name" value="Nucleoredoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13871">
        <property type="entry name" value="THIOREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13871:SF96">
        <property type="entry name" value="THIOREDOXIN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13905">
        <property type="entry name" value="Thioredoxin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Thioredoxin-like fold" evidence="8">
        <location>
            <begin position="51"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="200"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="206"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="218"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0010905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="228" mass="25663" checksum="ABB9985644A0EF43" modified="2023-09-13" version="1">MATTNDPVTNPETTARIARAKSTIDKRQSILFKIKLQDAAGKHVPVYEVANKLVGFLCSAGRYAVCQELSAIVDNFLEKHPGFTIIYISLDTSEEAFNRTMQAHPKWLAIPFNDPIKLDILNEWQTKGVPCLGIYDPIEHEVLTNWGGSCLRFNYDHCFEEWKQGGEGVTFWQMLKGWWYYKAPVGIFKDLTDEELAKNGFPGLEDSSNSSGSSSSSSDDRLESKKDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYM4</accession>
    <name>A0A9P6SYM4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Grainyhead-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">GRHL1_1</name>
        <name evidence="8" type="ORF">BGZ80_000159</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001028">
        <property type="protein sequence ID" value="KAG0012153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYM4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007604">
        <property type="entry name" value="CP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057520">
        <property type="entry name" value="GRHL1/CP2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040167">
        <property type="entry name" value="TF_CP2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11037:SF20">
        <property type="entry name" value="PROTEIN GRAINYHEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11037">
        <property type="entry name" value="TRANSCRIPTION FACTOR CP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04516">
        <property type="entry name" value="CP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25416">
        <property type="entry name" value="GRHL1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51968">
        <property type="entry name" value="GRH_CP2_DB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Grh/CP2 DB" evidence="7">
        <location>
            <begin position="320"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="563"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="19"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="129"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="179"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="192"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="230"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="270"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="297"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0012153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="759" mass="85739" checksum="4A35BD9E18510489" modified="2023-09-13" version="1">MSASLDPSHSSSYHQQQDSNNSNNNSNTNNSNSINNINNNNNSGNNSINTNSSGNNNNNNNNSNNGNRQEDYPQQFNQNLNQNQPNPNQQYQPQQYQPQSYYYQSGDYSHHSRQQQQQPQGFARNQGGPYSQPSPQQQHYYQDQQQQQQQQQQQPQPQPQQQQQQQQQQRPEDYYHQGHSPSSTMNSQGKNQQQQPQQPQQYQSQYQPQYQPQYQPHSQQQQQRHGGMNSPYHQQQQPQPQQQQYHSQQQSRLLPSPSVSLTPDEYLNQRDYNNVGDTSISGNSSAGQNRHEQNERASVSVSAASGSLQGSSSPRSENESSLRFKVTLDAQTAAMQHQGDTPVTYLNKGQFYTITLQDGEEYDGEINSVIKVTFHEEPHRKLAARYWSFWLSQQANPKTARALDIEKASSTGMMEVQSKTFDRISFKWNGKAGAKLMVRFNCLSTDFSRIKGVKGIPLRVHMDTTLNGGTLGSGDQEQVERSYAKIKLFRDKGAERKNKDDHKHLEKMWDKMRGKNADTNPLSQVLAPVQNVSVFWECLDHQEDAAEDETLGLSETLAQENLDSDINSSSGGGNINGGSDTTGGLLTPSDETEGLPSPSDFNALVPASRKRRRPNDDSGGMVAQTMISPMDRLPHYVRGASLDGLASSDQLLDRDPNYVPQIRKKKQPSLCLYIKIGGESVYRAVYLDRLTLAELTLKLSEKLEIQSSTISGVYRKTTKKELMVRVDDSMVAQMTDELDMVVEYDFNQQDGSVNLTLKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZ60</accession>
    <name>A0A9P6SZ60_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_011601</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000953">
        <property type="protein sequence ID" value="KAG0012654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZ60"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0012654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="297" mass="33629" checksum="F7D3F0E7AA664CCB" modified="2023-09-13" version="1">MHHPGVVLEVVLSTMVEHVPQGLSTATLSLALTDGQDNIPSTDLLLDKTIQGFQNTVIRKLDAFQNQVTALHSQAVVTQQITRKVCELQKQTIDRLAMIHHKTDAIMAQNFNLAEYDIPRLFIVLPETSRSWDPASMFRTKFRLRFICMGVEHFERRDGIILPKLHLAMHEGYVIKKPTELFKKYRPLLTAMLKMAGNFVPVVSAIDAVTSKGIEYSLKCLETTETQSRMSEDIEVNLAQNNLTDFLTGVREVDGPDLRLLRSYLLETSSGDPLGNMYRITTHSGYVKWVCHDCLML</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZW6</accession>
    <name>A0A9P6SZW6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">E3 UFM1-protein ligase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">UFL1_1</name>
        <name evidence="2" type="ORF">BGZ80_011047</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000840">
        <property type="protein sequence ID" value="KAG0013482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZW6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061666">
        <property type="term" value="F:UFM1 ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990592">
        <property type="term" value="P:protein K69-linked ufmylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032434">
        <property type="term" value="P:regulation of proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034976">
        <property type="term" value="P:response to endoplasmic reticulum stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018611">
        <property type="entry name" value="Ufl1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056579">
        <property type="entry name" value="Ufl1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31057">
        <property type="entry name" value="E3 UFM1-PROTEIN LIGASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31057:SF0">
        <property type="entry name" value="E3 UFM1-PROTEIN LIGASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09743">
        <property type="entry name" value="E3_UFM1_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="E3 UFM1-protein ligase 1-like N-terminal" evidence="1">
        <location>
            <begin position="23"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0013482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="314" mass="35765" checksum="39498CA186ECB238" modified="2023-09-13" version="1">MSSAIWNSFFGTSDSKEDLEGPSSLSEDACGDLVHSLVRLGYLSNIVPSLDGKSFITHDQLSKDILIQLEKRNGRVCLLDLPKVLNANLSDIQDRIHDLIRSKPGAMVLVQDELLKVEYLNNMTAQMNEELTRQGYLTTIDQCRKHKLDIDFMRQFLKDRVGGVIPGQWDTVDRGLVIAPQFLEKEKAALLKALNDLKEPTSLQTLRSRHVVQDQLFYGLCDLLSKENLELPGLFRGTNDQGIFAPHSYEQQQTEWIETFFKNNGFIGFLRAGLDQKKRSIRSKGVSAIKSSNNSYTRDTCCERKYLVNRRRNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0S7</accession>
    <name>A0A9P6T0S7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Endoglucanase</fullName>
            <ecNumber evidence="9">3.2.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BGZ80_009037</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 8 9">Belongs to the glycosyl hydrolase 9 (cellulase E) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.4" evidence="9"/>
    <dbReference type="EMBL" id="JAAAID010000512">
        <property type="protein sequence ID" value="KAG0016678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0S7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008810">
        <property type="term" value="F:cellulase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001701">
        <property type="entry name" value="Glyco_hydro_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033126">
        <property type="entry name" value="Glyco_hydro_9_Asp/Glu_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22298">
        <property type="entry name" value="ENDO-1,4-BETA-GLUCANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00759">
        <property type="entry name" value="Glyco_hydro_9"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00698">
        <property type="entry name" value="GH9_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4 9" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="6 8 9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 8 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 8 9" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040539417" description="Endoglucanase" evidence="9">
        <location>
            <begin position="26"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="498"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 9" evidence="12">
        <location>
            <begin position="91"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 9" evidence="12">
        <location>
            <begin position="136"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="43"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="398"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="540"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="43"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="553"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="444"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="453"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="562"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0016678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="562" mass="61244" checksum="9DE5A58759FA0351" modified="2023-09-13" version="1" fragment="single">MKASSHSFLWVTSVLVITFLSEISAQASPSPSPSPTTITRAFQPTTRATTTTSTFPTSTGLPFSEPLPQYPTFPADPRDNRTSPSFPDSEYVKLLDYTLLFYEAQRAGRLPANQRVTWRNNSVLTDGQDVGLDLSAVGISTVDNNYWGPDTNIPLPRPSYQVNITNPGTDIMADAAAAFASCAVLYRDKLNDTAYSNTLQTHATSLFNLAETARPQQVYQNVVTDAACCYASSGFVDELAWGAAWMYRLTMNPVYAQKASNYVNQFNAGGIQTSPITWDDKTGLIYILMANTTIGTSNINSQWVRLATQFGDVTVAARDPCEITNGGMYYCTGNSGDDSSVVAANAALAMYLLADVLESTGGSASKIKKYRSFALQQNDYLLGNNPMKTPYVVGVHPNSPQNPHSAPASGGTDVGDIDNSPEIESHTIYGALVGGPDRNDRFEDVRDNWKQTEVALDYNAPFNGLMAYQVMTSKLSPPYVVIPSGRPELPPILNGMEIWQIILIIIGAIFVIIGIGAFVCYRRRNQIRAWAAARRQRKTRKAAANHPLKPMAGSNSRQNISS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0U3</accession>
    <name>A0A9P6T0U3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Kynureninase</fullName>
            <ecNumber evidence="4 5">3.7.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Biosynthesis of nicotinic acid protein 5</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">L-kynurenine hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">BNA5</name>
        <name evidence="6" type="ORF">BGZ80_009181</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>3-hydroxy-L-kynurenine + H2O = 3-hydroxyanthranilate + L-alanine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:25143"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:36559"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:58125"/>
            <dbReference type="EC" id="3.7.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 5">
            <text>L-kynurenine + H2O = anthranilate + L-alanine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16813"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <dbReference type="ChEBI" id="CHEBI:57959"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="EC" id="3.7.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4 5">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 5">Amino-acid degradation; L-kynurenine degradation; L-alanine and anthranilate from L-kynurenine: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 5">Cofactor biosynthesis; NAD(+) biosynthesis; quinolinate from L-kynurenine: step 2/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the kynureninase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.7.1.3" evidence="4 5"/>
    <dbReference type="EMBL" id="JAAAID010000528">
        <property type="protein sequence ID" value="KAG0016502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0U3"/>
    <dbReference type="OrthoDB" id="5978656at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030429">
        <property type="term" value="F:kynureninase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034354">
        <property type="term" value="P:'de novo' NAD+ biosynthetic process from L-tryptophan"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043420">
        <property type="term" value="P:anthranilate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097053">
        <property type="term" value="P:L-kynurenine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:L-tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019805">
        <property type="term" value="P:quinolinate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000031">
        <property type="entry name" value="Kynureninase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01970">
        <property type="entry name" value="Kynureninase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010111">
        <property type="entry name" value="Kynureninase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01814">
        <property type="entry name" value="kynureninase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14084">
        <property type="entry name" value="KYNURENINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14084:SF0">
        <property type="entry name" value="KYNURENINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22580">
        <property type="entry name" value="KYNU_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038800">
        <property type="entry name" value="KYNU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 4 5" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="3 4 5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="4">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="164"/>
            <end position="167"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="249"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="252"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="274"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="305"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="333"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="4">
        <location>
            <position position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR038800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0016502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="457" mass="51502" checksum="5362EE6B8B6BA4E1" modified="2023-09-13" version="1">MSATKVAPQAQLDEFLAQSKASSFLDPAFAAFMDEHDPLKHLRSEFVIPTRGQIAPGADRADESCIYFCGNSLGLLPKTVSRYVNEELQVWGEAGVNGHFNHRFGRPWVRIEETVQEQSARLVGAKKEEVAVMNTLTSNLHTLFAAFYTPTAERHKVLIESKAFPSDHYAIESQIRWHKLDPKDSLICQEPREGEFLLRTEDILETIEKHGHEIAVVAFSGIQFYTGQYFEMEKITKAAQAKGCIVGWDLAHAAGNVPVQLHDWNVDFACWCSYKYLNSGPGGIASIFVHERHANSLDRNRLAGWWGHDKATRFDMVNVFKPMPGAAGFQHSNPSVLTTTALLGSLSVFEMTTMQEMRAKSYLLTGYLYHLLMNEISRDVLDIITPADPEQRGCQLSLVFKRGKMMDIFEGLAARAIIGDERKPDVIRVAPTPLYSRFEDVRKFVTELKELIAEIYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T142</accession>
    <name>A0A9P6T142_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Extracellular metalloproteinase</fullName>
            <ecNumber evidence="13">3.4.24.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Fungalysin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="primary">MEP5_1</name>
        <name evidence="16" type="ORF">BGZ80_009412</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="12">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the peptidase M36 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="13"/>
    <dbReference type="EMBL" id="JAAAID010000561">
        <property type="protein sequence ID" value="KAG0016140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T142"/>
    <dbReference type="OrthoDB" id="3227768at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09596">
        <property type="entry name" value="M36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011096">
        <property type="entry name" value="FTP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050371">
        <property type="entry name" value="Fungal_virulence_M36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001842">
        <property type="entry name" value="Peptidase_M36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33478">
        <property type="entry name" value="EXTRACELLULAR METALLOPROTEINASE MEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33478:SF1">
        <property type="entry name" value="EXTRACELLULAR METALLOPROTEINASE MEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07504">
        <property type="entry name" value="FTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02128">
        <property type="entry name" value="Peptidase_M36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 12 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 13" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4 13" id="KW-0645">Protease</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 13" id="KW-0964">Secreted</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="8 12 13" id="KW-0862">Zinc</keyword>
    <keyword evidence="10 13" id="KW-0865">Zymogen</keyword>
    <feature type="domain" description="FTP" evidence="15">
        <location>
            <begin position="88"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="308"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="343"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="309"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="483"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="293"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="482"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="486"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="512"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR601842-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR601842-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU364017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF07504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0016140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="695" mass="77624" checksum="63DCA5B787717195" modified="2023-09-13" version="1">MKITKTQSYSLVAAMFAVASTVSAHRARVQPFGPELAHKEYLTHSSLASSSWGSFAGRGNDGVFFTGSAANPQQVALDFVEQHLTDSDYIVKNAYTSKHNGVTHVYLRQRIDGLEVVNGDINVNVDKHGNVISYGDSFYKGNRQKSLTIKEWIKKEAESFQEGRQLDFGRWRHRIHRYQEESDVPEPKAAISPQDALVSFARYLNVEIPRPEDMDIVSINSLRSDKVDIVMTNCPLTADGKVPVTQAYIQNADGELELVYDFQVEMKDTDNWFHAQVNAETGKIVQVVDWVADASYNVFPMGINDPEEGERKLLKDPHHPPASPLGWNRQAQNKNFTTTVGNNVYAGDNRRNGNDWQNNPKPEGKLDKDGELVFDFKLDLEKDPSSYIDAAVTNLFYWNNQVHDVFHHYGFDEESGNFQENNFGRGGLGNDAVVANAQDGSGYNNANFATPPDGQHGKMRMYVWDVTDPARDGDLESGIIIHEYAHGISTRLTGGPANSGCLGWGEAGGMGEGWGDFFATMFRQKKHHNYESEFGMGSYANGGQGIRRFPYSTSLTVNPETFKVMDGPAYWGVHAKGEVWAEMLFEVYQNLHLRLPFTEDWYTNDKTSYANTLVLQLVVDGLKLQPCTPSFIQARDAIIQAEKVLTDGKYHCDIWKAFSKRGLGPKAKVVGANSPFGSIRTESFDLPKACSNDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1K7</accession>
    <name>A0A9P6T1K7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RNA polymerase I-specific transcription initiation factor RRN3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_007504</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RRN3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000386">
        <property type="protein sequence ID" value="KAG0018149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1K7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001042">
        <property type="term" value="F:RNA polymerase I core binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001181">
        <property type="term" value="F:RNA polymerase I general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006361">
        <property type="term" value="P:transcription initiation at RNA polymerase I promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007991">
        <property type="entry name" value="RNA_pol_I_trans_ini_fac_RRN3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12790:SF0">
        <property type="entry name" value="RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12790">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IA RRN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05327">
        <property type="entry name" value="RRN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="260"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="560"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="609"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="609"/>
            <end position="650"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0018149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="699" mass="78977" checksum="480A91DCEC3C64E4" modified="2023-09-13" version="1">MKRSISTPTAASAAMVSTEQIADFERQRQGQIMMTTYISSAIREKKQGNPTPYEELIAQLTVSKPEPLTPTKLLQWIQAMSQCISLLDKSCSTLIDAMLQINWIAQDDVFVQNYMSFLGNIVSAHAFYVVPVQSMLVKKLITRHKPSTLENAPAISRERQYDRVHQALKYILDLIPTGPTSLFPLLAAEFPHKRESIHAHITYVKNILRVLEYIPVLRNQILGVVIDRIIQIDVEIQVELEELEDSDTEVVYDWDVPEYAEEDDEDSDSDSDSDSDSDSEALEVTVLNIKDMTRKLDGMLFLVFSYMKGYIDSCQHLNDPSGQPPAPIQELFLVLLSIFMKTILQTFKSRHTQFLLFYCISLSPQFSDYFLGALLQQILDKSQPQVVRVASAAYMSSFVARAKYLDVRQVGMVIQMLGGFALETVEQVDTGSNVMPDAERYAVFYAVVQAMLYIFCFRWKVLTIDGGKSQSNRDDFESAGMILGNMDGASEPSTEAPATRQWHSDLACLQRIVTSRLNPLKICSNNVVKQFARISNSLNFMYIYPILEQNKKIFIHSTSSGAGSDGSGAGSNGQSNGGALPHELETFFPFDPYRLPQSAPFMRGIYQEWEDEDEDEDEDEEDYDEYDEEEEDEEEEAEGDADEDDEEDMDFIGRHNAEDENKDEEDETLMNQSVLAMSISPSPAHFLVQGMTSGLSKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2B5</accession>
    <name>A0A9P6T2B5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_004858</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000243">
        <property type="protein sequence ID" value="KAG0020057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2B5"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051834">
        <property type="entry name" value="RING_finger_E3_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011016">
        <property type="entry name" value="Znf_RING-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45931:SF3">
        <property type="entry name" value="RING ZINC FINGER-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45931">
        <property type="entry name" value="SI:CH211-59O9.10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00744">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="14"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="48"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="7">
        <location>
            <begin position="118"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="170"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="170"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0020057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="205" mass="22984" checksum="DB75478EAFD53A78" modified="2023-09-13" version="1">MSSRIAVLDQRSRILLLVFMIWTIIGIGFLGANNAIRDSSCMPSHDPVFSLAFKIIVFHSSLLGFYFLPCSSFLLSRVVPTSVSSGLSRTATKPMIDKLSSTPMIEGMFGGDPEEAVCAICLGEYAPDETIRFLPCRHHFHLECVDQWLLTDKSCPLCKRDIDKPVVNDRKLHGNNRNDEEANNNDHHHITDSTMTSDRFQVIVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2K2</accession>
    <name>A0A9P6T2K2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004430</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000226">
        <property type="protein sequence ID" value="KAG0020305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2K2"/>
    <dbReference type="OrthoDB" id="10369943at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="13"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0020305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="212" mass="23087" checksum="2203F24078DBA0A8" modified="2023-09-13" version="1">MSFLKRFKKKKSSPTVSMPSSTPRSSMQSSRPLLGAYKITMTPEENIHMIRENFYPLRTMKNHSTLLIGLLLAVAAIKAAPVPDINPANYDSFPLDSMAHRGDTKGVAPPEVPSYNAPEGMMSKRSDPIDGVPHGLLGKRGAPLDGIVERPLNLASFLDPLSHGLQERDDPLDSAPHGLLGRREAPLDGAPHGLLGKRDDPLDGVPYHNYPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T316</accession>
    <name>A0A9P6T316_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_002735</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000169">
        <property type="protein sequence ID" value="KAG0021266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T316"/>
    <dbReference type="OrthoDB" id="2130629at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY MULTIDRUG TRANSPORTER MFSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718:SF9">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY MULTIDRUG TRANSPORTER MFSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="69"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="136"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="165"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="198"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="225"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="257"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="289"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="329"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="363"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="392"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="416"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="501"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="70"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0021266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="558" mass="59807" checksum="8BBAF74104F3A1A2" modified="2023-09-13" version="1">MSSTDSIRTKECEVITIEKTAAADFQDTATTVVQDTIVEENLANNDVDLEQQSENQTKLSAIQLKLAPLMLYVVSMAQFIDIMNGSSMTVALVDVSNSLGFDSFSIQWIMSSYIVTFGGFLLLAGRVGDMYGHRNVFLVGQIWFGIWSLVVSFSTSPAMFCITRALQGIGASMSVPTALGLITTTFPAGPKRTSALSIFGGFGAAGAVVGLLIAGAFISSVGWNWIFRFSSIFSFTLFVLGAFIIPSTPIKKNLPRIDVAGALTATSSLICIIYYISTGSATGWASVQTLPVLAAGLVLFVAFVWIELRLVANPIMPFRIWRLKNFSSAFIAILFLQGQFQGFVYYTTLIFQNVMGYTSMQTSLAFLAHSLATIVTFTILGKILPKCRLKPFVLTGFVFRCAAALMFAFVDTRTSYWTLPFFGLIVHVIGLGTSVLPAQITALKDAQNEDQGVVGALYSTGMQIGAPLGLAIVTAISENSVSAKDQAESVNMLMQSYRNGLFGVVGLGVLGLIVSIFLMPNNPATPPVVHAPAPASISAPESEPVEPMIAAAEEKLST</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T330</accession>
    <name>A0A9P6T330_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tubby C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_002674</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TUB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000167">
        <property type="protein sequence ID" value="KAG0021305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T330"/>
    <dbReference type="OrthoDB" id="8775810at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061512">
        <property type="term" value="P:protein localization to cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.90.10">
        <property type="entry name" value="Tubby Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025659">
        <property type="entry name" value="Tubby-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000007">
        <property type="entry name" value="Tubby_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16517:SF7">
        <property type="entry name" value="PROTEIN KING TUBBY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16517">
        <property type="entry name" value="TUBBY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01167">
        <property type="entry name" value="Tub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01573">
        <property type="entry name" value="SUPERTUBBY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54518">
        <property type="entry name" value="Tubby C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubby C-terminal" evidence="3">
        <location>
            <begin position="140"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="240"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="55"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="251"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0021305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="420" mass="47335" checksum="FA2965F42F5E4162" modified="2023-09-13" version="1">MAHNSPSTGPQISSSSSIARNSGGHNPYGSRLLPMDSSNFLPEVPQPGGSMTYSDEYEDSYDQYDEDGDDDFNYQETSGQGNGQEVDDYIPTEPSALVQPAPNPLPEPHIINQPMNYNVPFSFGSKLDLISPKILHDIVMSPVPQGKKFMCRIVRKNEGMDKRMYPIYELSLEEPTRPQRVFLLRATKKKRSRGSYYAITSDKDNIYDYNRKASDTNYGVLGKLRSNFLGTAFNVYSNGRNPFSTGEQGEDANHEQPSMEKEKQKSKRESSNSNMPVRQELGAVIYNPNVLGLKGPRKMTILMNTMTEEGEMVEKRPTHVKDTLIGRMTEGDMSDLLVLRNKSPQWNDETNSFVLNFGGRVSLASVKNFQIVHDNDLDYIIMQFGRTSQDNFTMDCQYPMTPFQAFAFALTSFDAKLACE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3D9</accession>
    <name>A0A9P6T3D9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001521</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000135">
        <property type="protein sequence ID" value="KAG0021879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3D9"/>
    <dbReference type="OrthoDB" id="2395988at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="229"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="287"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="374"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="417"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="551"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="647"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="335"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="432"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="453"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="477"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="555"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="659"/>
            <end position="669"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0021879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="697" mass="75536" checksum="D179EAF2B1B402BE" modified="2023-09-13" version="1">MVRQRSNSTYRASQDPPETPLTPLTPRTPRSPHLHRSRLMTPTHSRTRASLKREHEDLDLDLDFDLVDAPRNLSRLSNTNTNTNANPTPSEILSMDLNTLALHCNNTNQAAAMPSARLSDEGLEHLNLNLPFERFLSPSRSLSSKTFSPSKASPESCHRYPTRAPSHESQSAQSTPVKNRSTIGDRISTPPSTGVAQRSTLISPPHTNARQFMTDEANNLFLTQSPRAIRTPRRMANSGDQSGVSLSIEKPARVPDLASLAPQADETPVGPFSSLDHILHADLNEDDAVETESVQSSAGDFEKENHTPKFTEESGNPFYVGGTKRHTRSASKVDGSTTPTGPSSTSSGTITRSRRLALGSISPWRWNTFDEHTGLTSQSNVKGAKSLGCTDGTSNSSCKADRSVSEWVESVVFQQRGTTASSDPGGVAGPISTASSSTTQKNRQSMGGKALFTSSMSSTSTSLIGPPLGGKSLGAKLPEHHPNSAEAAERKGGPSSIVAKLTASVIQPHSVAFNRRAQQLAGRIYYWKHGSYHLVSEQDKQQWPGEWKFEVFQDPESPGSSPQGENSSSGSTAATYSGKGKLTDRQLRGPASKRTRIHRESLSGPLEHTINNSVSDLGDGTNGNIDFQNNDTDLSQLTGVNDEQDVALPPSPSHRASKMRQNAARSAKQSHLDARYNFRERRMLNEPLPSRSRRCGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3Q1</accession>
    <name>A0A9P6T3Q1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_011588</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000095">
        <property type="protein sequence ID" value="KAG0022643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3Q1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="312"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="450"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="312"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="471"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="510"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0022643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="559" mass="62769" checksum="2F5E33746E3A0304" modified="2023-09-13" version="1">MASLNTKHSLPSKATSNPHHSSSSSAQTICYQHMLPTELWHLIVAYISPPDLFSLYNTSTYMRAISAPSLVQAMATKTIQLYFYQEYVRRVGVRFEFDHFDLKRDRIVYRPQVLDLQHRFRSGITLQSPHLEEAAVFTPSNEKLTPQQVRCTEGRYYTIPRNRSTRRTLSKTSLISSPSLSGLTELEPVAEPASETIANVTEEEHTTSTATGAERTSQKRITTSNRGYHGGMNFLDKSCPIQVRKDGIQELDGTKYCFLQEYPWSLEYQVAYEPFGVPLKRNPRSTSYSNNDGTKKRRQFFFDIRADLRAEAQAQAQTQAQEQAGMESANDNSSDGWNVFPGDEDTLLQSGLSDSTNSNSISASHGYRYFRALRFECSMNFLDLKRATRNIIGRWLEGKVQRWKKVLGGKKPMIQHHADVLSDSAESSSRVTKRKQNRKVIQVIDSILGPPAKLPANLNNTVNRWHPSMTDSGGENSDNVNSSDNNNNSDNNNNNSNNNNGHSRNRNRSRSASTSTSTSDNTNNSIGNSSSSRSFGVHVQPSISDFRKSDISLSTVTAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3Y1</accession>
    <name>A0A9P6T3Y1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">General transcription and DNA repair factor IIH subunit TFB5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">GTF2H5</name>
        <name evidence="9" type="ORF">BGZ80_009520</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the 7-subunit TFIIH core complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the TFB5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000058">
        <property type="protein sequence ID" value="KAG0023396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3Y1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000439">
        <property type="term" value="C:transcription factor TFIIH core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005675">
        <property type="term" value="C:transcription factor TFIIH holo complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006294">
        <property type="term" value="P:nucleotide-excision repair, preincision complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1220">
        <property type="entry name" value="TFB5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035935">
        <property type="entry name" value="TFB5-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009400">
        <property type="entry name" value="TFIIH_TTDA/Tfb5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28580">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28580:SF1">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06331">
        <property type="entry name" value="Tfb5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01395">
        <property type="entry name" value="Tbf5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142897">
        <property type="entry name" value="TFB5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 8" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU368032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0023396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="68" mass="7657" checksum="20341FB87FA0E4DD" modified="2023-09-13" version="1">MVKAVKGVVVECDSSVKMIILGLNEKGQFIIEDLDETHVFVDASCVDQLRLDIDEILNENTYKVEESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T4P2</accession>
    <name>A0A9P6T4P2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Aspartate-semialdehyde dehydrogenase</fullName>
            <ecNumber evidence="4">1.2.1.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BGZ80_003722</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the NADPH-dependent formation of L-aspartate 4-semialdehyde (L-ASA) by the reductive dephosphorylation of 4-phospho-L-aspartate. Mediates the second step in the biosynthesis of amino acids that derive from aspartate (the aspartate family of amino acids), including methioinine and threonine, the latter of which is a precursor to isoleucine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-aspartate 4-semialdehyde + phosphate + NADP(+) = 4-phospho-L-aspartate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24284"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57535"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="1.2.1.11"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="10">
            <dbReference type="Rhea" id="RHEA:24286"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 2/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 2/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the aspartate-semialdehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.11" evidence="4"/>
    <dbReference type="EMBL" id="JAAAID010000020">
        <property type="protein sequence ID" value="KAG0024377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T4P2"/>
    <dbReference type="OrthoDB" id="1894490at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004073">
        <property type="term" value="F:aspartate-semialdehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18130">
        <property type="entry name" value="ASADH_C_arch_fung_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02315">
        <property type="entry name" value="ScASADH_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000200">
        <property type="entry name" value="Aspartate-semialdehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.360.10:FF:000016">
        <property type="entry name" value="Probable aspartate-semialdehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051823">
        <property type="entry name" value="ASADH-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000319">
        <property type="entry name" value="Asp-semialdehyde_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005676">
        <property type="entry name" value="Asp_semi-ald_DH_pep-lack"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000534">
        <property type="entry name" value="Semialdehyde_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012280">
        <property type="entry name" value="Semialdhyde_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00978">
        <property type="entry name" value="asd_EA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006416">
        <property type="entry name" value="PRK08664.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46718">
        <property type="entry name" value="ASPARTATE-SEMIALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46718:SF1">
        <property type="entry name" value="ASPARTATE-SEMIALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01118">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02774">
        <property type="entry name" value="Semialdhyde_dhC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000148">
        <property type="entry name" value="ASA_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00859">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01103">
        <property type="entry name" value="ASD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="7" id="KW-0521">NADP</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0791">Threonine biosynthesis</keyword>
    <feature type="domain" description="Semialdehyde dehydrogenase NAD-binding" evidence="14">
        <location>
            <begin position="6"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="13">
        <location>
            <position position="153"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="13">
        <location>
            <position position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00050041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR000148-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0024377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="360" mass="38911" checksum="B5BFE626977EFB7B" modified="2023-09-13" version="1">MTRVLKAGILGATGTVGQRFILLLSEHPGFTIHALGASPRSAGKAYAKATKWKMSQPIPANVRDMTVQACEPQNEFKECDVVFSGLDADVAGDIEMAFLKANLALFSNAKNYRTHEDVPLIVPLANPSHFDLLTHQRAKHQLSKGFIVTNANCSTSGLVVPLKALQDAFGPLSKIVVTTMQAVSGAGYPGVSSLDIMDNIVPYIGGEEPKMEWETLKILGGLNQDATAFELLKGTKVSATCNRVPVIDGHTECVSIEFERRPAPSVEEVIKVLENYRTEAQELGCHSAPEHAIIVSRDDDRPQPRLDRENGNGYSVTVGRVRECNVFDIKFTLLVHNTILGAAGSGVLLAELAQKKGLIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MCQ5</accession>
    <name>A0A9P6MCQ5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Condensation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_008809</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the NRP synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004905">
        <property type="protein sequence ID" value="KAF9991933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MCQ5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043041">
        <property type="term" value="P:amino acid activation for nonribosomal peptide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensation_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF11">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Condensation" evidence="5">
        <location>
            <begin position="6"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9991933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="151" mass="16941" checksum="03341217441B0F62" modified="2023-09-13" version="1" fragment="single">MIKMSFPSRCDLDRYIGALQNVVDRHDILRTAIMWKNLSTPAQVVLRKARLSVKELSLDPINGSILDQMSKIFDPREFSVDLTKAPLIQLAVAQDTDKSWIVVELMHHLIGDHSTLDVMTDEIKANLDGRGDSLPPPQPFRNLIAQARSGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MD05</accession>
    <name>A0A9P6MD05_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Peroxisomal membrane signal receptor PTS1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">PEX5_1</name>
        <name evidence="9" type="ORF">BGZ80_008263</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peroxisomal targeting signal receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004426">
        <property type="protein sequence ID" value="KAF9993134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MD05"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005052">
        <property type="term" value="F:peroxisome matrix targeting signal-1 binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016560">
        <property type="term" value="P:protein import into peroxisome matrix, docking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024111">
        <property type="entry name" value="PEX5/PEX5L"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10130:SF0">
        <property type="entry name" value="GH08708P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10130">
        <property type="entry name" value="PEROXISOMAL TARGETING SIGNAL 1 RECEPTOR PEX5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14559">
        <property type="entry name" value="TPR_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="9" id="KW-0675">Receptor</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 8" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="8">
        <location>
            <begin position="132"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="8">
        <location>
            <begin position="166"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9993134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="296" mass="32542" checksum="2ECD1839BE7A63E8" modified="2023-09-13" version="1" fragment="single">LAARGNLTESILALEAAVQKDPTDAAAWHQLGLRQQENERETLAIAALLKAVETNPKELNAWLALAVSYTNENCRVDAYDALQSWIENSDQYSGVKNTVSGGQGRSAQERHEYVTGLFLEAARTNPGENLDPDVQIALGVLFNVSEEYEKAVDCFRAALNLRPDDYMLWNKYGATLANSHNTTAAIEAYFNALNINPSYIRARYNLAIACINLGQHREAAEHLLSALALQNAGDAARGLMVGSTSKTPQSDGGVGGMSQNVWETLKMTMYMLGRSDLAQRCETSRDLDAFRDEFDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MDB3</accession>
    <name>A0A9P6MDB3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004423">
        <property type="protein sequence ID" value="KAF9993145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MDB3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9993145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="175" mass="19323" checksum="EAA3347905C8B42F" modified="2023-09-13" version="1">MPTPTVHAPTPTSTNPRMVDDFSDPSRYSSEENALGYYTGDDDTVTQKTTVQGDWILLTFDTSSYWYSTLGAPNTCNDYSQFTKVNFAVRYPTSTITGFNIVLQTTNNSTCTGLNQYPVDVTSLITAATAGNDGWLHIEVRLTQFTGADLTRMRAITLSGFKSAGQVEIDYIYFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ME31</accession>
    <name>A0A9P6ME31_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ATPase with role in protein import into the ER</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">KAR2_2</name>
        <name evidence="8" type="ORF">BGZ80_007864</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum lumen</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004107">
        <property type="protein sequence ID" value="KAF9994293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ME31"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.10:FF:000009">
        <property type="entry name" value="DnaK-type molecular chaperone BiP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000153">
        <property type="entry name" value="Endoplasmic reticulum chaperone BiP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.34.10:FF:000002">
        <property type="entry name" value="Heat shock 70 kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="372"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9994293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="396" mass="43586" checksum="E5D45B4000BCCD11" modified="2023-09-13" version="1">MDYFVKQYKKKNNKDITKDLKTMGKLKREVEKAKRTLSSQMSVRIEIDSFHEGNDFSETLTRAKFEELNMDLFKNTLKPVDQVLKDAGLEKSDIHDIVLGGGSTRIPKVISLIEDYFGGKKASKGINPDEAVAYGAAVQGGVLSGESSADSIILLDVNPLTLGIETTGGVMTKLIPRNTGIPTKKSQIFSTAADNQQTVLIQVYEGERQMTKDNNQLGKFELTNIPPAPRGVPQIEVTFELDANGILRVSASDKGTGKTETITITNDKGRLSEEEIQRMIKEAEQFASEDQAIKERIEAKNSLENYLYSVKNQVNDEAQLGAKIDAEDKKTILDEINKKIQWLESDGVTASKEELDEKKEEIEAVVNPITSKLYGSAGGAGSGPAPTEDMPEHDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ME90</accession>
    <name>A0A9P6ME90_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007592</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003910">
        <property type="protein sequence ID" value="KAF9995166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ME90"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="224"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="29"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="166"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9995166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="293" mass="30911" checksum="B4397B4A1BC7B4D2" modified="2023-09-13" version="1">MASAIYQSRSNTAFSSKTLKSGTTAGVPTSSRYNSTNTSSTASTTKHAHSLSSTSTISYPHPSIHPPLRLLTSATCLETLTCLVSAQSPPHSPTFTAMGLPKSTSPGSGGSGSRASSILDGIQSALGGALGASSSSPPSASGTLKSSYSAAQESLADFSIPASKRSTNVSTAASSYTSSNQQSSKIETSPDDPQMGVARSRSNYVSFPNFDDIDFVDVAMVEDREEDDDDDHPDWYGPDSPPEGQRPTVLEEKMIRPHQIDSRIGVGMPTTPSQHWLLQLENFHELHVNGVQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MFB4</accession>
    <name>A0A9P6MFB4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_007184</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003633">
        <property type="protein sequence ID" value="KAF9996714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MFB4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050562">
        <property type="entry name" value="FAD_mOase_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356:SF2">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356">
        <property type="entry name" value="FAD-DEPENDENT MONOOXYGENASE ASQG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="19"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9996714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="342" mass="37525" checksum="422DF06F8BDAD034" modified="2023-09-13" version="1" fragment="single">MSDLNNPSIHYTPNPSNPKIIIAGAGLGGLTLAILLEKASIDYEILERAITLKPLGSAISLAPNVMPLFEQLGLLDGLKRISLEWMRGGLYRESPSGESLELLNDTDISVLKELSGYASAIMSRPDLHALLLSHVPSHKIHLGKRVLSISQSNENGVLVRTSDGSTHVCDILVGSDGAYSGVRQSLYDLMKKEGCLPSSDGEGMKVCDMSILGTTNSIDPSIIPLSKDGFARCDCILGYKKPHSWRYFKVPGNRICWRVNVQLQTQSFEQSDAFKNSDWGSESSGSIEEDWRAFKLPLGPNNSYITIGALINSTESRNITKVMLEEKMYTTWHHGRTVLMGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MFG4</accession>
    <name>A0A9P6MFG4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_007173</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003626">
        <property type="protein sequence ID" value="KAF9996754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MFG4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9996754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="96" mass="10973" checksum="C2515EC0AAE4DF74" modified="2023-09-13" version="1" fragment="single">SAFEEYYSERFPKAKADLESSKRMASLVSGQTWVDDIMRKITLNLMPSSLMNATFVKTLAYRPQANFMPKIGYRGSGRVDPQKESKRYLQEKATAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MFM7</accession>
    <name>A0A9P6MFM7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_007018</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003520">
        <property type="protein sequence ID" value="KAF9997398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MFM7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9997398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="106" mass="12442" checksum="AC58AC1BFED1E106" modified="2023-09-13" version="1" fragment="single">RRRIREIKSDDFKNEARFFSIYSPGRGFKAMGLRHCPASQHVMLTHSYPAFILPSNEEGWKYQLQGLVHLLQIRRCMKEIISQYVEALAESDPERFETTVEAARKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MH58</accession>
    <name>A0A9P6MH58_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006341</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003125">
        <property type="protein sequence ID" value="KAG0000566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MH58"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="15"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0000566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="213" mass="24308" checksum="C4F1447379084D69" modified="2023-09-13" version="1">MTIMSSKTAQEDPAVEALRKELAAVKLDLRNTKQNLLDAEDDLESSQADLSAALSSLAERDIELGNTKIALANSEHARLNTERVCLEANRDRVLSRPHGKQEVFVVLKFREPQPLPVGGYRLFALQRKAVKSTLDQFIADNPELDATEVNELRFDRSPRGQYVYQQMKDDAEAPIEFSRRNFKLREGRLESEMIAYIQNVFNTHIHNQENQVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MJ87</accession>
    <name>A0A9P6MJ87_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GST N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_005574</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002745">
        <property type="protein sequence ID" value="KAG0004676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MJ87"/>
    <dbReference type="OrthoDB" id="414243at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050213">
        <property type="entry name" value="GST_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571:SF150">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0004676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="173" mass="19602" checksum="BD921E7637E49C27" modified="2023-09-13" version="1" fragment="single">MVSNNSKLSTETMSQLAQARDNKYKLLYYPFHGVVAGLRAMFAMSDADYTFIHPEDWAVQKPTTPLGAMPVLYETTATGETLELAELSVLEYYIGQKNGWVGDNLWENNLVKMYHSSSQAVVDKLVTTVVRAPKENYDQMLEIYITKIVPEWVEYHERALKANGSNGHYVGDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MJJ0</accession>
    <name>A0A9P6MJJ0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005766</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002834">
        <property type="protein sequence ID" value="KAG0003623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MJJ0"/>
    <dbReference type="OrthoDB" id="2360307at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040163372" evidence="1">
        <location>
            <begin position="23"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0003623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="234" mass="24829" checksum="79E073ED9DE6F4D7" modified="2023-09-13" version="1">MRISTFVSAAFGLALFTASTQALPTPNSAVDLLKRGDDNIMNSLVKLFVKEQSKLLVDACVDLQTNVCADVIVKVNANVNVLGIKSHVEVKDLEVRTKVDSDAEVKALINADVNTLVIANIDAHVRAVVGGICSVLDHACLKKNAHTIVADVVALINVDIQKLIVQVKADVAAHVKVRVTAHLKKLAVNAGIAKADVSAIVRLRSDIDVHLKAFVKACAEVLVDAKLIAKVAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MM81</accession>
    <name>A0A9P6MM81_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Exosome component 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">EXOSC5</name>
        <name evidence="8" type="ORF">BGZ80_004794</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RNase PH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002400">
        <property type="protein sequence ID" value="KAG0007343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MM81"/>
    <dbReference type="OrthoDB" id="27298at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000177">
        <property type="term" value="C:cytoplasmic exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071028">
        <property type="term" value="P:nuclear mRNA surveillance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071051">
        <property type="term" value="P:poly(A)-dependent snoRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016075">
        <property type="term" value="P:rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034475">
        <property type="term" value="P:U4 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11372">
        <property type="entry name" value="RNase_PH_RRP46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="entry name" value="GHMP Kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015847">
        <property type="entry name" value="ExoRNase_PH_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050080">
        <property type="entry name" value="RNase_PH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11953">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11953:SF1">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT RRP46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03725">
        <property type="entry name" value="RNase_PH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="Ribonuclease PH domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0271">Exosome</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="6">
        <location>
            <begin position="3"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="7">
        <location>
            <begin position="106"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0007343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="213" mass="23010" checksum="F07FFB649A43E68F" modified="2023-09-13" version="1" fragment="single">GSSVLCSVVGPAEVKIRDEKLDKATLDVVARPLVGLPGVKDKAREQAIRETLEPLVLSGLHPRTGIQIVVQTMKDDGCVLSTAFNATILALLDAGIPLKSILGSVTCIIDSKTNQILLDPTTEELALAKSTHVFVFDNKTSVSSTQQENDNMDQDNADSALGAVLFSDSTGLFTEEEYFECAQVCFKATQAVHGFIRTAVQKKLEKEYQQIQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMK1</accession>
    <name>A0A9P6MMK1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-actin-capping protein subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">CAPZA2</name>
        <name evidence="9" type="ORF">BGZ80_004035</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the F-actin-capping protein alpha subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002102">
        <property type="protein sequence ID" value="KAG0007960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMK1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030863">
        <property type="term" value="C:cortical cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008290">
        <property type="term" value="C:F-actin capping protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030036">
        <property type="term" value="P:actin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051016">
        <property type="term" value="P:barbed-end actin filament capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.210:FF:000003">
        <property type="entry name" value="F-actin-capping protein subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1140.60">
        <property type="entry name" value="F-actin capping protein, alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.210">
        <property type="entry name" value="F-actin capping protein, beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002189">
        <property type="entry name" value="CapZ_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037282">
        <property type="entry name" value="CapZ_alpha/beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042276">
        <property type="entry name" value="CapZ_alpha/beta_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042489">
        <property type="entry name" value="CapZ_alpha_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017865">
        <property type="entry name" value="F-actin_cap_asu_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10653">
        <property type="entry name" value="F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10653:SF0">
        <property type="entry name" value="F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01267">
        <property type="entry name" value="F-actin_cap_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00191">
        <property type="entry name" value="FACTINCAPA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90096">
        <property type="entry name" value="Subunits of heterodimeric actin filament capping protein Capz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00748">
        <property type="entry name" value="F_ACTIN_CAPPING_A_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0117">Actin capping</keyword>
    <keyword evidence="4" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040397954" description="F-actin-capping protein subunit alpha" evidence="8">
        <location>
            <begin position="32"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="134"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="197"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="142"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="256"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0007960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="607" mass="67289" checksum="DBEAE0284649FB71" modified="2023-09-13" version="1">MRFFAETSVKPTRLPLLLGLLLTVFNPSAVALPDSISLSFLDEDGAVIGQPQTISYASCAILEVSQLVSNDGVYATARTSDLRSALNLYKDSTCQILVGSTVGEWANVAPVANMVAIRWEGTADSTLTTGVIRPDGFPKGMSEQTKVDNSSTSSETQLILDPSKGKLLVGLVAAVLVVGVIIGAYQVYQASLYEAPPKEKKEKKPNGLNTKKIKKKDAYFKKPIRNDQQAFQRLESPAPSVMTRPPMSERRGFRDSQLSEAPSSVELNQQRSMYNNGSDTVMIDMHGAAGFRSSQLRENGSALNLIQFESDSNNSYGRVVRDHDKAINSSISFPSLYYTKTEQSIMATVEEKIKIASGFLKTAPPDVRGLVGDDELLDGGILNALAEYNTEELATAIVSKHGQIENDLFLHPKTNKVFKLDHFRQIASDPVDHTVDEGIEELRKTVEKDTEEYVADRYAEGVSAIYGSNGGVTIAIVHNKYSPSNFWNGRWRSIWTLDTATLEVKGTLKCKVHYYEDGNVQLETSKEVEEKLNNSSSDPPKVISKAFLELIAAAELKYQTALNESYHDLAENTFNGLRRALPYTRTKLDWNKACYREMWVTLYWHSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMU1</accession>
    <name>A0A9P6MMU1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_004885</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002444">
        <property type="protein sequence ID" value="KAG0007259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMU1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="274"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="357"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="72"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="274"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="371"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="492"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0007259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="533" mass="59306" checksum="B1F5D5901DD11B87" modified="2023-09-13" version="1" fragment="single">MTTEAVIYVSLALVLLTRIYVFISPPEFLEEHKDRRYHEFHLYRQYHLHKQYDKSEFNQKRLSEDQNDDTSSLHSSSSTPNTRRRPSEGEPFLDSLHHPSDELILLGSEPGAHPFPLRRLSIHSLSRLDPLDIPSPTSASTTPLSSKEGGRGLWSRILGTSEPASVPNYLSLDVSEVHYNGSLKEFDNDPEVQASIQGLKSGVKDMTKECPTMTMVWECGRWCCLEGRTLYILRALEWKGQVRVRVLVDKDPVTLAVTEDYWKAAGMTSEFAPSTPLMSSTSLTPMTTSPTTPDTLHPASWNLEGDDSAKKAHDNYIQLAAAAMDSSAVAYGPSLTNGTAQELLANEPQARISLSTAGGLSLPASPTGHDADDEDDQGDDDDCEVESDGYLEDDENDENDEEDIEKSVEALSLDPNQRNAVTPDYSERQKLTTGGQPRPNLFRPMSQRSKLTAIPSSPPSPIQVPNPGRNISFDPVISSQRNGPGSIGAVRQQQQQQQQQQRHYRERRISIPEFMLPPPLKDERAYLIIDPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMY5</accession>
    <name>A0A9P6MMY5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_004793</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002400">
        <property type="protein sequence ID" value="KAG0007342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMY5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0007342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="84" mass="9561" checksum="E451CFB3628A296F" modified="2023-09-13" version="1">MEPCQSCHVSPKNDDSWSFTFARNISFMDDTAELYHPVIASCIIQNLLGFKVSWSDFKKKHVVHIISIEIAHLQELESLIGANQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MN66</accession>
    <name>A0A9P6MN66_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003622</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001971">
        <property type="protein sequence ID" value="KAG0008283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MN66"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0008283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="102" mass="11314" checksum="B48E75AF967C9EF2" modified="2023-09-13" version="1">MLESEWITAVIPSLKASNISALSDAGVRLEKQWKSSKETRRHQRSEDGDSIKTHKLMKCSLYQHRKAVLDHSGETMRDGLDAPDPSLGSTHTQSLSSASDYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNP0</accession>
    <name>A0A9P6MNP0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">alpha-amylase</fullName>
            <ecNumber evidence="4">3.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BGZ80_003656</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endohydrolysis of (1-&gt;4)-alpha-D-glucosidic linkages in polysaccharides containing three or more (1-&gt;4)-alpha-linked D-glucose units.</text>
            <dbReference type="EC" id="3.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the glycosyl hydrolase 13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.1" evidence="4"/>
    <dbReference type="EMBL" id="JAAAID010001985">
        <property type="protein sequence ID" value="KAG0008248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNP0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004556">
        <property type="term" value="F:alpha-amylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11318">
        <property type="entry name" value="AmyAc_bac_fung_AmyA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013776">
        <property type="entry name" value="A-amylase_thermo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015237">
        <property type="entry name" value="Alpha-amylase_C_pro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006046">
        <property type="entry name" value="Alpha_amylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="GH13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006968">
        <property type="entry name" value="PRK09441.1-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006969">
        <property type="entry name" value="PRK09441.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43447">
        <property type="entry name" value="ALPHA-AMYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09154">
        <property type="entry name" value="Alpha-amy_C_pro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001021">
        <property type="entry name" value="Alph-amls_thrmst"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00110">
        <property type="entry name" value="ALPHAAMYLASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyl hydrolase family 13 catalytic" evidence="11">
        <location>
            <begin position="8"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="490"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="498"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0008248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="539" mass="61832" checksum="3C500813DC4D365B" modified="2023-09-13" version="1">MLGEHENITMFQFFEWYSPADKQHWVRLKEQASLLSSLGLSAIWIPPPMKGISEFDVGYAPYDLWDFGEFDQKGTIPTKYGTKDELKAAIEECHKHGVKVYLDAVLNHKAGGDEIEVFKAIPVAEDDRNKELGEAYDIEAYTKFLFKGRNKKYSDFQWHFHHFTGTDWDAREKKKAIFKIVGENKSFAEDVDSENGNFDYLMCNDVDYNHPDVVAETEKWAEWIDALKHTSAGFIAHLLNHVRKNTDRKDFFAVGEYWKDDVGDLESHVENNGGIHLFDVPLHFNFARASKEGNSFDMRTIFDGTFVKTSPESAVTFIDNHDTQPYQSLESFVEPWFKPLAAALICLRFDGYPCLFYGDFYGIEPKCADEPETGLPGRKEMFSRVLLARKEFAYGSQNDYFDHVSCVGWVRYGDEHHPKGLAVVMSNSEAGSKTMDVGKDKAGQVWVDMMGYWKEPVTINEDGWADFHCHAGSVSIWVQKEEGKSWVTCEESTLEEEEKGKEEQQADLEAEHPELPKPLDDGWEHLLEDDKPKKGRREP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNP4</accession>
    <name>A0A9P6MNP4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">protein S-acyltransferase</fullName>
            <ecNumber evidence="1">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_003009</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="1"/>
    <dbReference type="EMBL" id="JAAAID010001772">
        <property type="protein sequence ID" value="KAG0008831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNP4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24161">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24161:SF85">
        <property type="entry name" value="PALMITOYLTRANSFERASE HIP14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81995">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="876"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="65"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="114"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="182"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="327"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="456"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="536"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="569"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="735"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="796"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="184"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="203"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="219"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="248"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="402"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="476"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="536"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="569"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="582"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="763"/>
            <end position="774"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0008831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="895" mass="95879" checksum="1423028D94C1D9C5" modified="2023-09-13" version="1">MQNQPSGAVSTTSIVAASSSKPSATPAKKPPPFQNLGLHSGAAMGNLGLVKFALDNGQPIDSAINGVLPIHAACCSNANVAVVLYLIERGADVNARRLPRKLSNEKGVQAVGTTGSTPLHFAAANGCLSVVDILLRHGAIVDMTDKYGSSPLSVAAARNHPDVASLLRQYSAMQRGVQDFTPDSEVKDVFPERRGSLDTHRGAATTPRTSTSSSSSATGQQKESNTQSIPVPSSRSDRATRAPGQRRISLPSIVESPSSPVILAPPRQSCDFDRMPQSTEPLVMSTAFIRSTPSQPTRNIASAQTRSDDRPSKMLIRDQPDLNLETTKDQTRRSITRSHTTHVTESNVLPKPNGASTVKRRKSMESGAFLSPQSALSVHRRKSFDQLAIMDSSDSKSRRSSDASTASQGTSSSGTTRTSNTSVSTEDATDLAEELAVRKEQQQKQQQQQQQQQKQQQQQQQQQQHKQKQPQKQHQGSVSKSTGSGNASALPSHLTRSISQSALENIRLRRLPASLASDSNPRQSLDLQRLASNMDRSAEKARNFEARNDSDSDLPGLLFHRRSLQETSFNVEDVSTTSPQDSSAPRRSTSSISSGHSGSTGTVNVSSRLSRMWSSSNSGSRESLCLRDGSIPGSSSASNWNANEFGGACGEAAAQNLAHPDINRSKGTEEFGINRDEWTPPCVTIMKEHVSSLPANSAVTDNDDNDVSRGASTANRLHAGAAMASFTYDKDVTHMDTSEANPLGHGTNTVKDSATGHDKEQATSSSTTSTKTMTMDSEQNAEFSSGCEQNKVIPIYGRGKEQVDPRSTAPKRPAGQRPEPLRNPNQTGFTLGAGQVTFTGTMIPPFMFSPFGIQYGGSYTANLGPNGAAQTPMQAYVSRLFFMLGTLILVGILLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPB2</accession>
    <name>A0A9P6MPB2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Vacuolar membrane-associated protein iml1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">IML1</name>
        <name evidence="4" type="ORF">BGZ80_002849</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001725">
        <property type="protein sequence ID" value="KAG0008984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPB2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990130">
        <property type="term" value="C:GATOR1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904262">
        <property type="term" value="P:negative regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010508">
        <property type="term" value="P:positive regulation of autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027244">
        <property type="entry name" value="IML1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055213">
        <property type="entry name" value="IML1_double_psi_beta_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048255">
        <property type="entry name" value="IML1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13179">
        <property type="entry name" value="DEP DOMAIN CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13179:SF8">
        <property type="entry name" value="GATOR COMPLEX PROTEIN DEPDC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12257">
        <property type="entry name" value="IML1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23013">
        <property type="entry name" value="IML1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IML1 N-terminal double psi beta-barrel" evidence="3">
        <location>
            <begin position="60"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="Vacuolar membrane-associated protein Iml1 N-terminal" evidence="2">
        <location>
            <begin position="155"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="491"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="669"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0008984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="688" mass="77312" checksum="09CD6B54872B6BE7" modified="2023-09-13" version="1" fragment="single">MFNSTPNNQARMVPSTASARGSSSLHQNPSAGGNNIANSAYDSQQMPTAAAPPPIATKSLHVHQDTYSKRDFLIDPPSFPGVQPNDLFEIYDPALPSDASKRLVIQWTGPDKDTQLKSPVQVSLANNIASKFGLIARRDAVVQRVDPSRYAAKYVELTFRDQYIGRSDMWRLRTSLVGTSVYETQKILYLGCIKAQVKEIYVGNLSVPSGYITSETRIIFRSESAKVFIFIQMSREMWEFDEDGEIFFEKVIFGFLPNLFARWRGKRDGKLELESPTNHVVSIVLFSRIFYQGEEEERFRIDGYPGGQTGLQKDEEGRYYQDFYKVVIDWEARTDWTTAIIPLKEEIMRYQRDILLRPAGPYQILSGENSFAFEGNVLESVNLALNSLDKHYVDRDLQRTGLSIVMITPGSGIFDVDKKLLRLTTERMISSGIGLDMVCLSKIPAHIVPLFRWKGPVADSNGILLMNQGSSHSSSTFVPTSGGGSLMVRSASAFSRPNSRPPSVKESSAEGRPATPWSRPFKPNTSNPQPEVQIDMSDPLYYDAPPTFPSSPTKTYYLMPHWVDCMFYVGSLEHNPQKFYTRCKMYELQMMGIMEHEISSISIPYLNESYNAQYSATFGKRLSSTDALAMTKSQLSKAIDFEKHDNDIFHDPNSPLISEIKMLNISSSQGSRSTVTDPFSLDTLDSST</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPT6</accession>
    <name>A0A9P6MPT6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_002949</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001753">
        <property type="protein sequence ID" value="KAG0008890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPT6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="445"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="448"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0008890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="464" mass="52880" checksum="7F69BC67CACF3BF3" modified="2023-09-13" version="1">MPLSKAQIKWAIEKTPFQEHVLFPNFVRRFKLTDKDAAIELFEELLELSSVRAKRRTKLKAAFSDFRLHSEEKFWSKYALEVKTKVTALNAGVIVHDLGLQEQKLASFRLMSENDEIEESYYISDSSESEEDEERNVTVQADNAATTLSLNQQDEDTEEATSTSEASDESPIIDDDEKQKLLSMVEHLKHDQCEWLIGESCVDCKFYEYQKECIEALVVNQIMKQDIADAMSIIGVFAPFLPTERMKKCFGTDLLHQIVMPVPLKILSIDFNAVMTAIQHAQNGNLLDARKSLDPVDVKLQTMIQTLQGRKPDRPDIAIKIGDHEVMFGEVTGPHQQSYDFKNKWDLFRLTRFGKSFLDAGNSVAPLIQAIYTRGSYMRLKARMRGMYLLEEVGKFSIPTTVTEISSLVSSLPVLLLAQTDLQKILNNKISERKRSSQYEDLIDAKKRLQGKSKTKASHTNKKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQA4</accession>
    <name>A0A9P6MQA4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Velvet domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_002085</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001502">
        <property type="protein sequence ID" value="KAG0009770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQA4"/>
    <dbReference type="OrthoDB" id="5599552at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.3960">
        <property type="entry name" value="Velvet domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021740">
        <property type="entry name" value="Velvet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037525">
        <property type="entry name" value="Velvet_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038491">
        <property type="entry name" value="Velvet_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33572:SF17">
        <property type="entry name" value="SEXUAL DEVELOPMENT REGULATOR VELC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33572">
        <property type="entry name" value="SPORE DEVELOPMENT REGULATOR VOSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11754">
        <property type="entry name" value="Velvet"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51821">
        <property type="entry name" value="VELVET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0749">Sporulation</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Velvet" evidence="7">
        <location>
            <begin position="57"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="76"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="36"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="114"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="140"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="157"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="173"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="217"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="250"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="268"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0009770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="454" mass="50968" checksum="9AF6D76E5969DC72" modified="2023-09-13" version="1">MPSQAQRETPRHAEEQRVSHNHSSTSSSQVVIKPDITPKREEKQNHQPLRQRPQQEEPPISKARIKIVQQPLHARMCGFGEKDRRPIDPPPIIQLFLDDDPTYNLPRTPPKPIKPIKPRKKKGKKKGGKPGRKPGKKAQEAAAAAAAAEAEATAAAEAKKQEEEETKKKEERDEGMESDDEQENDDEPGSHDEDSDDEFHEEDDEDHKMGDNSIDESNPKDKSPRPAKKTTAERPEPQESTAERREPIKEPTPTPPPPPPAPKRRGRPPRDKSLAGTKHSRDNQNDSDSEVEWPRYEGGAEALRVDPLYVLHVSLWSEDGTEVRSMIATPGQTDPPKLTRILMGAVVVSPILLNDEHGNPGWYFSFPDLSIRTEGTYTLKFSLMRFASFDFDDRGGSHASTLIAEEISKPFSVYSAKKFPGMTESTELSKAFAKQGLKIPIRNDLRVRKSIEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQA8</accession>
    <name>A0A9P6MQA8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sphinganine kinase lcb4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">LCB4</name>
        <name evidence="6" type="ORF">BGZ80_002495</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001618">
        <property type="protein sequence ID" value="KAG0009334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQA8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001727">
        <property type="term" value="F:lipid kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046512">
        <property type="term" value="P:sphingosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001206">
        <property type="entry name" value="Diacylglycerol_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050187">
        <property type="entry name" value="Lipid_Phosphate_FormReg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045540">
        <property type="entry name" value="YegS/DAGK_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12358:SF31">
        <property type="entry name" value="ACYLGLYCEROL KINASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12358">
        <property type="entry name" value="SPHINGOSINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00781">
        <property type="entry name" value="DAGK_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19279">
        <property type="entry name" value="YegS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00046">
        <property type="entry name" value="DAGKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="NAD kinase/diacylglycerol kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50146">
        <property type="entry name" value="DAGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAGKc" evidence="5">
        <location>
            <begin position="101"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0009334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="471" mass="51961" checksum="408609847DDA0B7F" modified="2023-09-13" version="1">MSSFPFILNVHKGHHQIQLNYNGSHLEFDAPDAEGPRSIKTVEILNITIEGDNSLIISACTSKHGPKKEATLEVLEFTFNDKAQATLWQFNVLTHVYKDLKRGRHFKVLVNPFGGQGHAKRIWEHTAEPLFKAAGCTYDLIYTTHRYHAKEIAKELDIRAYDAIVSVSGDGVLHEVINGLMERPDAVIAHKLPLGAIPGGSGNALSFSLLGEDNGSHVGNAVLGIIKGRAMPVDLCSVTQGNNRFFSFVLQSFGLIADVDLGSEHLRWMGEARFTVSAVGKLLSQATYSCELAYIPAETNVNKIVAQYNEHHNQPVVWANQTHDELDQNHQTITDKFGSVTDPIKESDPWVVEKDQYATVVGAKLPWISKGTISHPAAQPNDGLIDLLIFPKNMGRIAGVQAMIGVETGDHIFSDKVRYMKVKAFRLTPEGTSGYISMDGEHTPYAPYQVEAHRGLISVLTIDGRYARSMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRE5</accession>
    <name>A0A9P6MRE5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_001503</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001342">
        <property type="protein sequence ID" value="KAG0010417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRE5"/>
    <dbReference type="OrthoDB" id="655030at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050562">
        <property type="entry name" value="FAD_mOase_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356:SF2">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356">
        <property type="entry name" value="FAD-DEPENDENT MONOOXYGENASE ASQG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="9"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="304"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0010417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="456" mass="50859" checksum="D4F16017D5557E17" modified="2023-09-13" version="1">MSSGGTRPTVLIVGAGIGGLALGAILERANIPYEIFEKSSSMKPLGSAIAVGPPVMPLFTQLGVIDQIAEKGIVFERSDVYSEKDGLVLQLDFVAGAAEKFGWPGYIISRPNLHNILLSLIPPERILLNKRVLSHVETGTGIMIRTSDNMTHEGNILVGADGTYSAVRQSLYGQMDKRGLLPSSDKKPLRSSTICLVGQTRPFEPKGYEFNDNKKCTYESILLDGKPVFIVTFTTAENTICWKLIEYLDKETSKTNNIFRSSEWGPEAADVMCKEVRDYPVVRGMKMGDLIDATPKEVICKVMLEEKLFETWTYGRTVLLGDACHKMNPSGGLGAQTAMSDAVILANYINTLHTVELEDVEKALKTYRNERYPIGKQAVETSAVMFNIIKQDWRGRMIRYILKYIPRWLWFMIRAQSVRCRPQISFLPLAEDKCQIKAIHQPSLEKTRPKNTAANA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRI7</accession>
    <name>A0A9P6MRI7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Amidohydrolase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_000922</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001202">
        <property type="protein sequence ID" value="KAG0011140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRI7"/>
    <dbReference type="OrthoDB" id="10258955at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008448">
        <property type="term" value="F:N-acetylglucosamine-6-phosphate deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006046">
        <property type="term" value="P:N-acetylglucosamine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11113">
        <property type="entry name" value="N-ACETYLGLUCOSAMINE-6-PHOSPHATE DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11113:SF14">
        <property type="entry name" value="N-ACETYLGLUCOSAMINE-6-PHOSPHATE DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="2">
        <location>
            <begin position="411"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0011140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="935" mass="101172" checksum="FF0F207F5072D455" modified="2023-09-13" version="1">MADYSSLPTHDQDEVGHAYEQPDKFAFLRNPRTLLLATAAIALLSTTAYYLGASNELSPKKVHFEGVGISANSFSHGLAKCNFINRENKHQYPAPESRRSNPRFVNGTLPTLFKNGYVFDGVSEAFKGDVLIDRGLIVQIGSDIKAPNNTVVVDLKGHILTPGIVDMHSHIGVDSWPALDATSDTNEMTQPLTPFIRSIDGFNPSDPAREWVLSGGVTTTLILPGSGNIMGGEAYSVKLRKVDTLSTDDMLVEAGVQDKWRYMKMACGENPKRYYGSFRHMPSTRLGEGWLLREKFAQASELKRAQDDWCDAAEDLPRFGRHRVDTPYPENPELESLVGILRDDVKLNIHCYETHDLEAMVRHSNEYKFKISAFHHGLDAYRVPEILKRAYKVVPTVATFAGKFGYKKEAFQSSVNAPKILADAGIAVAMKSDHPVLNSQHLVYEAAQAHHYGLSETLAIASVTSVPAKALGLDHRVGKIAIGMDADLVIWDKHPLALGSHPLQVYVDGIAQIENADESKWSTEGEPQKFEPLPDLVVPKDKDACTEKADSGVFTGIKKILLDDDEEFSSEGTLSVIIKQGEVVCAGHCGSEIAALGKGAPVYDIGGEGVVLPSLLSVGAPNLGLIEIAAEDSTGDGYQNLDSKFPFISAADGLKFGGLHMDEAYKAGILTAVTAPNSEHVVQGTSVAFLTGAENAFSPENAIIKEKVALHVRIGQDAKSKSFPTVSSQIGFLRSALEKGLSELFHPNDEFALAASGKLPLVIEVENRDEIVRLIQLKKHLEREGAKIRMSLLGAVEAWTVAEHLAEADIGVILRPYLCTPIQWTAQKCSPGAPLSEETGLSVLHKAGVTVGLAAHEPEDVRQLSWIAGWAKSDLGISEKEAVGLVSWNLAKIVGLPTNPSGLVIYNGDPFEFGAKVSAIVGGGKSGIQCNPRAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRN8</accession>
    <name>A0A9P6MRN8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">60S ribosome subunit biogenesis protein NIP7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">NIP7</name>
        <name evidence="9" type="ORF">BGZ80_000991</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Interacts with pre-ribosome complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the NIP7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001219">
        <property type="protein sequence ID" value="KAG0011042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRN8"/>
    <dbReference type="OrthoDB" id="27490at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042255">
        <property type="term" value="P:ribosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd21146">
        <property type="entry name" value="Nip7_N_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21151">
        <property type="entry name" value="PUA_Nip7-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.130.10:FF:000002">
        <property type="entry name" value="60S ribosome subunit biogenesis protein NIP7 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.450.220:FF:000001">
        <property type="entry name" value="60S ribosome subunit biogenesis protein NIP7 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.10">
        <property type="entry name" value="PUA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040598">
        <property type="entry name" value="NIP7_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055359">
        <property type="entry name" value="Nip7_N_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002478">
        <property type="entry name" value="PUA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036974">
        <property type="entry name" value="PUA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016686">
        <property type="entry name" value="Ribosomal_synth_fac_NIP7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005155">
        <property type="entry name" value="UPF0113_PUA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23415">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT/60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17833">
        <property type="entry name" value="pre-PUA_NIP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03657">
        <property type="entry name" value="UPF0113"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017190">
        <property type="entry name" value="Rbsml_synth_fac_NIP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00359">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88802">
        <property type="entry name" value="Pre-PUA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50890">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4 7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="PUA" evidence="8">
        <location>
            <begin position="95"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00054591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR017190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0011042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="180" mass="20772" checksum="2C748215CA85D279" modified="2023-09-13" version="1">MRPLTELETKTFFEKLAKYIGRNITHLIDRGDETYCFRLHRDRVYYVSESVMRKATSVGRDQLISLGICFGKFTKTGKFRMHVTCLDYIAQYAKHKVWIKPNGEMPFLYGNHVVKAHIGRVTEDTPEHQGVIVYSMTDVPLGFGVTARSTSDTRKMEPTAIVVFHQADIGEYLRQEDTLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRQ7</accession>
    <name>A0A9P6MRQ7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001238">
        <property type="protein sequence ID" value="KAG0010933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRQ7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="67"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="143"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="175"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0010933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="219" mass="24527" checksum="644F27296A8BB575" modified="2023-09-13" version="1" fragment="single">MLTASPIVALTDLAREHPVSNSSKHSEYLDRAEPRSSMTMDYTSSIPNGVRHQHYNDERGNEYPEEQQQQQQQQQQQQQQQHYTTNGNGHGHYSSALPPSSSSQSHYTHSSTAYLPPPIQTTPFATGNGNAVGGNGVHAMHNSFATPTSPASSASPLSPGNNYQQPQPQPPPPQQQQQQQQQQQPQQQQGQGHYEYEQYHPQSYHAHHAQYPQDHQQHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRY9</accession>
    <name>A0A9P6MRY9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_000763</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001168">
        <property type="protein sequence ID" value="KAG0011328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRY9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF38">
        <property type="entry name" value="ZN(2)-C6 FUNGAL-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="3">
        <location>
            <begin position="105"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="506"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="601"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="681"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="917"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="535"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="601"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="614"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="632"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="706"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="726"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="754"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0011328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1073" mass="119513" checksum="F41609D3B704AEB8" modified="2023-09-13" version="1" fragment="single">CNGLEPCMNCETAKIACTYNTLSPSKKRAHDAYVLQKRYEQTQHLKNADIIVAPFGELYIAGTPNNFGPLFAQLINLPRTEPPPSDFKNDKQRILAINDAEKLLIDCYFKHFNYYIPVLNRKTFMEQVTDPNQLMTLKVQKLLACVLATGFAVRQELGDPNVFHMMDPNYGALMSRKFNHFNTQNVFTSSIENCQCYLILTGFYSSVTNYDAVHNLVALAHSIAASQGLNRNKGLYYQFIDGKSHTLETIELGHRLFWCVVIVCSGYSLSHQSPFITSNDYDIPYPKRMPSDTHMDFQGVMQDDFDGIQDLHHFVPMYEIASRIADISCTATKQRPHTQVDEAREMLMEWRTKTLPEKLRITPHDMDAIEKQSRFSKFYHAISYMFEIALHHTFQLHESHRILGIHNIWTSYCYEAAIAIRNIYRTRMSKMNSHVILPVAAGAFANVVVSQVLGKAEAAQKYCDDIKAMLTDIVRASSSIERTRILGFVDHSYINVTKNADRKVDDFGIQAPNTPPGNELSPVHTAGSSPAQSSDTDEYVSEEEEEEEEEEEDEGMSDDEDDQEIRKDGREANITILSTSQRQQQQQQQQLLQQHQLQQQQQQHQQQQQHIQQTRSHPSMTSRAQSNPAMYSSSQQPIDQQQQQQRSIVDSSYTVQGYGEILQSPVSGETYAGTTVSYTDANGNGFPYSDRQQVQHRDSAVGPFSNDGSSHGQSVDQDTCFVQRGPRNQQHQSFSSGQSLDGGNVGLPRQHQDSVSSIASTSSASGFYPGPISRIENISDGQAATLAGQGMWDQQPNDTQHSKLNEYRTIIANNELTPQEHQQMIALSSSPTGPQTSASHGGFTSENYGDLNNNQYLLHQQHHSGYDVAPISLNTSQLFPGGFEGADSIQGSMLLSGDFGPDQQRFFPEMISPVSVTGNGKSLSDSSDLTSPISPASHQQHQQHQNMTIPNQNSDSIGNMLVYQQQHHQQGQVLDMHSFPGSREYGEMMRGGFGNGIGPDGSNGLVGLDGGMGGLGLPAEFGGEFFSSNIIADGGAGFDLINFTNGPQMDKMQQLFSSVARKGQQPQQPRNVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MS60</accession>
    <name>A0A9P6MS60_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_000446</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001093">
        <property type="protein sequence ID" value="KAG0011752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MS60"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="17"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="17"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="121"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="121"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="138"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0011752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="823" mass="90285" checksum="7A90C7D80131AAA2" modified="2023-09-13" version="1">MSATQPEGLSQELCAVYRDHVSGAITPLSKTVQIQPQLDSKSGEYIILWSDIKMIFKNPLHVRNGDAIVPFLRDEDLDFIHPLKILAHPGTVLNVVVETIEIETAMESLVIANTAVSQPTLATTNNTSQPQRDKLEPQNINEPSETLVSSVPETTIQYQSPDKASGDICNRTQLAAEQHIGSPADRGEDFEKHDGQDMDANYRRGLAYYLGEDVPQDYIMALECFLIAANQGSAKSQFTLGVMYENGQGANQDYCRALEWYQKAANQGCAKSQFNLGVMYDIGRGVIQDHIKAEEWYRKAAAQGIPEAQNNLGLLCHIGNGTTRDCSEAVEWYQRAADEGYAIAECNLGVVYDKGLGVTKDLSVAAEWYQKAASQGDAVAQNILGVMYRDGCVVVQDCSKALELFEKAADQGNADAQCHLGYMYENGKGTTKDLFKAMEWYRKAASQDNPVAQCNLGSIYQEGVCVTQDYSKAVEWYQKAADQGLASALYKLGVMYGEGTGVTQDSSKAMELHQKAASQGDVTAQYNLGLKYYSGSGVTQDYFKAAEWYRKAAKQGHSEVQHKLGLMYEEGRGVTRDIYVAVKWWGKAANQGNDDAQLSLGVLFDNGQGIFQDYSKAVDFYQKAACQGNALAQNNLGVMYRDGRGVTQDHSIAVEWFQKAASQGQASGQNNLGDMYNQGQGITQDYSKAVEWFQKAAVQGCAKAQNNLGSLYRDGHGVAQDNSMAEDWYLRSASQGNATAQNNLGDVYSKGQGVSQDYSKALERYQKAAVQGDDNSQNSLGNMYADGRGVMADISEAIKWWRKAAGQGNEDALHRLDMIQSKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MS89</accession>
    <name>A0A9P6MS89_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HCP-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_000549</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001114">
        <property type="protein sequence ID" value="KAG0011621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MS89"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052945">
        <property type="entry name" value="Mitotic_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43628">
        <property type="entry name" value="ACTIVATOR OF C KINASE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43628:SF1">
        <property type="entry name" value="CHITIN SYNTHASE REGULATORY FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0011621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="507" mass="56608" checksum="00C27B555074A6B5" modified="2023-09-13" version="1">MPRFHIKSEKFVILWDDIIAAFKNPIHTRNGDTVIPFLMDDDFTLIQPKRFSVYPGVVLDVVIEATGTEEDPGCLRYRHSRTSSSSSTLFTAPSNQSLSETELPIIDGYPKTTSRTHSVKREPQDHNEFLENTSIPAAEAVGIEEDRYRPSPSSSTLFTAPNSQTLSDAELPIISAYSKKNSKKTRTRRVKREPQDHSESPENASPPEIQHDRAPQLAPESQGNRSGHSNLLELILEEWYSYGPDSGNGVRQDYAKALDLFLRAAGQGHAGAQYRLLVMKENRHTIGSDYSKVAEWYQTAAGLGYPDAETGLGFIFEVGFGVTQDYPKAVELYGRAAEQEHVYAYCSLGFMYENGYGIPKDYSKAAELYQKAAFKGLAKAQHSLGIMLYYGYGVAENRLAAAELCRKAADQGYVPAQCDLGFMYMKGDVIPRDYPKAAELFRMAANQGYAEGQYNLGIMYKNGDGVPKNLYKAIDWWEKAATQGYADAKKKLDERHIGTLNGVLRYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MS95</accession>
    <name>A0A9P6MS95_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Reverse transcriptase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_001248</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001281">
        <property type="protein sequence ID" value="KAG0010706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MS95"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="102"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0010706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="737" mass="84356" checksum="3B5A9FF31BE2622E" modified="2023-09-13" version="1" fragment="single">MEQKFQQRLEEMENKHKESLAQMDWENKQKLNDMKKLQKVILDQREQELAEKSQESLEQRKTELKRDSALELKKLIEKQQESNSREHKELELKHQDVLKERLDDIEKENLKKLAEMEAKHQEMLDRRLATFLEEKSEFKQDKEDFRREREAFYKEKDEYQKTRDQLLISNTKMKTEMEICPLSKHEKQFVLPESHWSQITWQQAANKDIEVSGFAFVDDTTWLARSQADMQETLDIAQSFFSLHDIEINTKKTFLVILNSPADQNSILFGNPRTEIVALPATESTRILGVWISSKGGTRDVLPIVRKEMDPLVEVLSRKVITDKQCVYVLNNILLTRILYRCTLHILTPKELRKITSKCRNLVKQKAALPRDTPNSIIHHPRFYGLRQLQDLQAEDQISSLYYRLNDPTIVGDLTRARLLALQFQHRILSCPLAQPALLTSPPPNNLIGDIICLMKERGVSFSTNDILVPSSDTLTRQCTPQLEEPQMVPVDGNNPSRPISRPQSSDIALLGPEENPIVGFDQEGSSIPTVVPFGESLTLTSTTLDLTEQPYHGISMTNSSSLITPVITAHSVPDSIDSNTPVTSIPSSLSIFPVSSDFLDVGLLPAAADVMSVFPQPPPSAATTPSTQVMNPTLYLTPIQALFDKTEFKKFRHQLCDKGIWHLEQLTNSANTHLCTWDVAKARLRCRSRVPMWYTALRRNICVTEPDNFIQVSFVNDNQMSPTHLTIDNDKLTRLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSB5</accession>
    <name>A0A9P6MSB5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Aldehyde dehydrogenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_000364</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001073">
        <property type="protein sequence ID" value="KAG0011878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSB5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07102">
        <property type="entry name" value="ALDH_EDX86601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11699">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="5">
        <location>
            <begin position="4"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="5">
        <location>
            <begin position="299"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0011878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="417" mass="46135" checksum="B34755038F7E5EC4" modified="2023-09-13" version="1">MSPSTLSIVTPVDSAVFATVHISSSEEVQAAVERAAEAQKAWKRVPLKQRIETGRRFLEVFGSRKDELAKELTMQMGRPLRYTPGEIKGTQDRGKYMVDVAEEALKDVEIHEAGLEGKFKRFIRKEPVGVVLIIAPWNYPYLSSLNGVLPSIIAGNSVILKHSSQTPLCAERFGQAWTEAGLPDGVFQFIHMSHADTESLVANPLVNYVNFTGSVEGGHQIQKAASKKFIATGLELGGKDPAYVRPDCDLKYTVETLVDGSFFNSGQCCCAIERIYVHADIYDEFVQEFVKETKPGTPYMAPQVLTEVTHKMRVMSEESFGPVIGIMKVSSDEEAIRLMNDSDFGLSASIWTKDPEAALTIGDQIETGTWFMNRCDYLDPALAWVGVKDSGRGCTLSKFGYDQVTRLKSFHLKLVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSC7</accession>
    <name>A0A9P6MSC7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_000501</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001102">
        <property type="protein sequence ID" value="KAG0011697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSC7"/>
    <dbReference type="OrthoDB" id="2362121at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="10"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0011697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="471" mass="53491" checksum="3B63C1CA53D703F7" modified="2023-09-13" version="1">MATLDPFNLPEISSLIARHLNKRDLGSCLGVCKAWHNALLPHLWSDIDVKPSLGEQSLRNPDPNILKRYSHFVKNLEIRTFLLKEYVMPYPNLRTLNFVVTNGCSADLLSLNTSITHLTFNDQHYLEAIENQELWRAVADLPHLTTLIFDFGTTISAFDMSDFWQACTRLDGLFIFTSSVDCSVEIPDGMVFSRMRKLVLQEMYRIAPKDNLELIRRCPNLKCLTWYSVVDDDLEPAAMEFVRLAKNGAWPNLESLGIRVGLGDDDMATVLENISFVTKLEFDDSSFGLTSFTTLKRSFGMLKDLNVSNCPNMSSRMVQELLSSCPRLEVFMGDFLEAEDVLAGQPWVCLSIMVLKVCFTFRAGQSLMPAIYERLSHLTRLTSLNVGHELKGVRLSHHQGLDIQLEAGLGLLAKLKHLEYFGAKDLPGSPGLKEIEWMAENWRSLVAIRCRPQIEPEKLSKTKWNFWFSTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSM2</accession>
    <name>A0A9P6MSM2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_000500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001102">
        <property type="protein sequence ID" value="KAG0011696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSM2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0011696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="268" mass="31059" checksum="01812621D785CC6C" modified="2023-09-13" version="1">MSTISSLEIPEIFNLVANHLERRQVVTCLQVCKAWHNLLLPIVWHSVVLGGYRKGPTPKGPPKAALNRHRQFISRLEMHCTHMDLNIATFPNLRTLVFTLCIWRSLSKEYPMELFTLNPSLVDVTISGEFLPVIEGEFWKAMSDLPQLRIFRVHSLPPGIDEIEAFWNVCSKVEEASFWETKFPKTPIQSLELSFPRMRKLEIEACDADDYKEQLEFVRCCPDLEELLWTADRAHTEVDKFSIEVKQGKWPRLGKYEIRGKSKFCGVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSQ2</accession>
    <name>A0A9P6MSQ2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 12">Mitochondrial fission 1 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">FIS1</name>
        <name evidence="15" type="ORF">BGZ80_000203</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Has a role in mitochondrial fission. Has a role in outer membrane fission but not matrix separation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="12">The C-terminus is required for mitochondrial localization, while the N-terminus is necessary for mitochondrial fission.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the FIS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001034">
        <property type="protein sequence ID" value="KAG0012111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSQ2"/>
    <dbReference type="OrthoDB" id="421154at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000266">
        <property type="term" value="P:mitochondrial fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016559">
        <property type="term" value="P:peroxisome fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12212">
        <property type="entry name" value="Fis1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000179">
        <property type="entry name" value="Mitochondrial fission 1 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016543">
        <property type="entry name" value="Fis1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033745">
        <property type="entry name" value="Fis1_cytosol"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028061">
        <property type="entry name" value="Fis1_TPR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028058">
        <property type="entry name" value="Fis1_TPR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13247:SF0">
        <property type="entry name" value="MITOCHONDRIAL FISSION 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13247">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 11 TPR REPEAT PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14853">
        <property type="entry name" value="Fis1_TPR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14852">
        <property type="entry name" value="Fis1_TPR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF008835">
        <property type="entry name" value="TPR_repeat_11_Fis1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 12" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="7 13" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="4 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="125"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="13">
        <location>
            <begin position="74"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00025016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR008835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0012111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="150" mass="17196" checksum="6FB0A99556E16B14" modified="2023-09-13" version="1">MTDNLPSISDADSCLPDSQLEVLKKQYIREGEYVTDQTRFNYAWGLIKSKHRRDQTQGVLLLTDIYREVPDRRRECLFYLALGHYKLGNYNDARKFNESLLEFEPNNSQAHALRREIEDRVAKEGYIGMAIVGAVAAVGTIVLTSLLKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSU2</accession>
    <name>A0A9P6MSU2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_000121</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001019">
        <property type="protein sequence ID" value="KAG0012216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSU2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="287"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="318"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="371"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="417"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="471"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="498"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="575"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="588"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="601"/>
            <end position="621"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0012216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="621" mass="66685" checksum="A34DC656125B8F7B" modified="2023-09-13" version="1">MNLSQILNPPGSSTTTTGISSRQGRTSSTPPPSHSLSSGTTVLRFDTPLNGSTGGGTSRKHSSSVSVAQLEEQATYTPSTSKTTGGTYQKIKPNEISNGYSTHTFRANAPIQPSKETSTSAASNNTALPSIAPAGGTLCQLVMSHNTPQDMSSSMSAGKKKRRNNASNTSESSPFQDSFQSNPSDQHEATATTATTIPKKKASKKANQATQENESQPLEIRFVMTDKDDQDRQRNQKQALTSTPKDESPSQDSPGEDGANDFQSSPTPDFERNADGNGMILFIPQESSSATSSPSYSHGQSPSQSTTTTPSGAPRNEASLSLPSTPSGHASSGPTFVATGSVSPPLSEPTIRINEPARQSIKGSRPLVAQGDTTSGQLNSSTSRSPVASDSPPSKPIIQKNESSNNFSDDVEQQGAKGRDEHSEDNSRDVEEEDSDEMRQKEEAALTMTSFREMAMLQHHRPNHQAPPTAPAASPYHPSHPQQTSLNSDARRYSNGEYYTTSSYRDYPPSSYHPHSSNASYPTIPSSTSPIPSTGSHPHTSSHSGEYWKNSQGGATPKQDINGYAHHGQDHPQDPQRSAPQSGDNRYHHYSPHPSRSRSPVHHEPQYRGHANDHGYDRINQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MT26</accession>
    <name>A0A9P6MT26_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_000403</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001081">
        <property type="protein sequence ID" value="KAG0011828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MT26"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="376"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="52"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="230"/>
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    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="231"/>
            <end position="242"/>
        </location>
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    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="323"/>
            <end position="332"/>
        </location>
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    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="337"/>
            <end position="353"/>
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        <location>
            <begin position="383"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0011828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="399" mass="43689" checksum="6C056C3F8445244C" modified="2023-09-13" version="1">MDPKDTPSSTAKGPSCQSQQKPLHSALSDPANSRRQSSFTVRFAESALSSAPKSPLRPSTPRPRLASLEGFDYLPEIFDFKLLDGIQQDDNTEIDFSSHLTEKEYQDPESRVEPTSKVTEDEGYGLSTSGLEESKSFFKDEEGVTERTEDLRYVDSLLETYPIINAIDSSPEKSQHDATPENISLASPTDPVFCSKGSGKHLNLSSTVLSEFLLRTPSSVAPSTPQSTEISPTTPSWLSSPPLQIPIFAKTPRSARPTSFANSEVPKLHHLDVKRKIAAPRLFKPSLLRFTTTHESPQHPLELSSSTIGDGSEAGPSTPPGSPTTFGGFTTPNTERSEDDTIVEDSEIDEDTGNESVRDSVYSEVYYSADNENVDVKKGIDRSNPNFKTVETVTTKRDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTV9</accession>
    <name>A0A9P6MTV9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Arginyl-tRNA--protein transferase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ATE1_2</name>
        <name evidence="3" type="ORF">BGZ80_011097</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000850">
        <property type="protein sequence ID" value="KAG0013412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTV9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004057">
        <property type="term" value="F:arginyl-tRNA--protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030700">
        <property type="entry name" value="N-end_Aminoacyl_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007472">
        <property type="entry name" value="N-end_Aminoacyl_Trfase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21367">
        <property type="entry name" value="ARGININE-TRNA-PROTEIN TRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21367:SF1">
        <property type="entry name" value="ARGINYL-TRNA--PROTEIN TRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04377">
        <property type="entry name" value="ATE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-end rule aminoacyl transferase C-terminal" evidence="2">
        <location>
            <begin position="165"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="373"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="10"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="373"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="414"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0013412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="513" mass="59216" checksum="4A6241569937B20C" modified="2023-09-13" version="1">MYQHVDQSLNNKPNPNSNNNNNNNNTDTNRNTKDSSIEDGDASEFQASKHQRQVVNRFNNYIQEGDENFEKDIVSRQEARKQSSNAENKSSEPETTAPSIEPTDTSALAEVPAPGKKQKPRKPPKNVAADLITRIRSSEYLLSPEITSWKHRLRIVLEPASFTEEKYKLYVKYQMEVHHEPESKCRVSGFNDFLVSSPITATKTVGWREDDPGFGSFHQNYYLDDKLIAVSVIDILPECVSAVYFFYDTDYSSLSLGKYSAQREIALAESLSAKPGYETVQYYYMGFYIFTCPKMAYKGQFHPSYLLDPETYNWIKYDKCKEIIKDQRYSAFENPSTMNPLFEAKMKSIINHKRGQPENDYDSEDYEDDIEDWESVDEEDEEDENSDDNSDKEEEEGGEGEGSEDQGKRKKKRLDTTDEERRKKAAEAAERQRKKEIEKAFVETLALPPPGCLNTKDITDEDVKSILCLVRQRVVPVTDTDMYKYQSGIKDFVKEFYSYFGKDGWDDLFIILH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MV18</accession>
    <name>A0A9P6MV18_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_010206</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000687">
        <property type="protein sequence ID" value="KAG0014825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MV18"/>
    <dbReference type="OrthoDB" id="2383509at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0014825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="296" mass="33768" checksum="EF4D050CB3E88A6C" modified="2023-09-13" version="1">MQYNLEFGTFRQEACAFTFRAEIPPAPAIKVFSIPDLIDQVVLSIYRGAPRDFKKTQEKIRQLRLVSRAFFQAANPHFVVGLPFQKFLGREWMISPRITICGPYIRSIDLRAGNLCDVGLIKLVRGHCPNLEHITLLLEDTTRSFSSRHRYLTFFENVFSSSSIDADDNNVKIKISHWNNPVLEYLAVDKLVSRNRHYGNSDNPNELGDIEDDAMTVEPMRINATDAKALYELLKVTPELKSLTCHTVRWRGRGGGPEDLKLLKDCTWDYLEIDGNSSGSNLDNELKRYPSPTDSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVC7</accession>
    <name>A0A9P6MVC7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Conserved oligomeric Golgi complex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">COG1</name>
        <name evidence="9" type="ORF">BGZ80_010659</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COG1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000767">
        <property type="protein sequence ID" value="KAG0014078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVC7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017119">
        <property type="term" value="C:Golgi transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033370">
        <property type="entry name" value="COG1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31658">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31658:SF0">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="592"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="595"/>
            <end position="615"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0014078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="811" mass="90374" checksum="A32558256B254B15" modified="2023-09-13" version="1">MENNSYLTAGRLFRISKVIYDSLSAGMDDDEESRPVKVMETFPVVGRQWDAVSHFKAQILQKSHHHLKSSKESDLDVIETICAIMLLDNVTIKDMFRLFLAQRQTAIRETLDIKGGDIEGQIVKAIGILQATLFHVGHIFLAPEQGKISPLERHLRCLQQTFSIPSNITSTSTFSKDDILAPSALPNPTSSVIPKLYPTTPNIHLLVRYLPESVQNFTPFIHLDGARATFTQQDALQGIKRWMEDTQAMFSSGFEKLLQEVHSSTELVSIRSKVWTVLLQDEYALASKTKKSPFNEICCVLLDEPFSIWHTILRTGFTKTFQDIIVYSLDELSHQPEKLLRPRLGELDREDDTNHDIGKFVWNDAAVAKGTGLPSATEPLVQKIRGYVSGKTDLVAQTTGAFDGILDAIRSDQEQALVCERPSLDDTEDEDLDQYESLDLFRAKADTQQLVEYYQRCCVECIKVYTSGLEQLVKEAVQKPEKTRNTVQALDRAMTIGRVALGIASMGRAIQRALTPPKGRASTLNFAEARAAKSNVEGRVHDLVSGLQKVYLVSHEAWIENIEWKLNRYIKYYLKDSSWTDLATLAWEPIPSEGPASPSTSRRAPAATASTTATASEDAKTLLPFHCSTRLVTALHQAVQDMHRAGTGLMRPELIQALTAKLGLTVLRAVDQFLSDVADQTLQGSDNTPVVITEKGALQLLFDVKFVNLIFQSSLGNDSDLSLLSRSVLGRIRERIDPINLAVFEKPLDINAERQYGRVSALLGLLIQLNPIDSKRKANTTEKSPHVFAMAPLCPRFVLLPIGQKMPGRVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVD7</accession>
    <name>A0A9P6MVD7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_010002</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000652">
        <property type="protein sequence ID" value="KAG0015171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVD7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0015171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="353" mass="39301" checksum="CC56A31477154824" modified="2023-09-13" version="1">MTATSHLISDCKVTSIKIPARRPGLNARSTSASSVPQMTSIQIPSKESRIAAAINIPSPPLTPYIGRENDQDIGSDDIFSSRFHSKHMQDDEDEDGDGEELDKDMSALQMRQSSSAPSAMSPLEMMMSTNIAPTSFTFTSNLQSPSQATSEKRESYDMFVNTMEADYWKSVSTVRTTYFFDGIGRGGGFLAIPHIASHGNAKTNVICRLLEAWLTKKLVEPTISDSIPVLEDNIESSVQSIEQHLRHDPKVWSGISKSFIHIRCGHVFMLDTCCDDETIVHLGADEFYQDYPLFVDVEIKMQCDSNTTVTKEQSTELLVAFKNVTNRNNSGSIKQEEEPFVHRAVIAHEIARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVM4</accession>
    <name>A0A9P6MVM4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Peptidase M20 dimerisation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_010603</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M20A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000755">
        <property type="protein sequence ID" value="KAG0014174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVM4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006751">
        <property type="term" value="P:glutathione catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051458">
        <property type="entry name" value="Cyt/Met_Dipeptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017149">
        <property type="entry name" value="GSH_degradosome_Dug2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43270">
        <property type="entry name" value="BETA-ALA-HIS DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43270:SF8">
        <property type="entry name" value="DI- AND TRIPEPTIDASE DUG2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037237">
        <property type="entry name" value="Peptidase_WD_repeats_DUG2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 7" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="72"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="218"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M20 dimerisation" evidence="9">
        <location>
            <begin position="523"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="8"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0014174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="797" mass="88710" checksum="FBD9408955911D06" modified="2023-09-13" version="1">MSTRHETASLSRSSSFSVPNGQPQCAHTLTQEEDSVLSLAATEKLLFSGGQGVHGSDIHVWDLEHFQLKANLKGHLGSILCLTLREDGKWLFSSSGDGTVRVWDTETFRCLYHIHSSQDVGDVFSIVFSDALNTMYIGCQNTSIQWIDFSDSKPEIPHSHNITHNLRSHTPRFFEGTTNSKELDEQVIRYNIPDSCIVQNCHFGYVYCLLLGKVPNVEGEILFSGSGEGDIKLWKLKKGKAIEPLKTLKAGVDASTLTLAIHDGFLFCGSQGGNIKIFDLETFQLIRSIIAHDDDVLALVVRGSQVYSASADGVVKFWPIAKGSTQVESVESTTEDVMLYALEKWIAMPTVSGVPSQLEECRRGAKFLKSVLQQLGAESRLIPGAPGHNPLVYGQFSARSTISDERARPLNVLVYGHYDVIAADIKKWDYPPFKLTGKDGYLYGRGASDNKGPILACIFAASELQEEQLLDVNVKFLIEGEEENGSVGFFQAVEQNIELFQEADVLLLSNSYWLGEDIPCLTYGLRGVIHSTLTINSKNVDLHSGVDGGAVSEPLIDMVKVLSELVNPDRTAKIPGFYDCIRPLSSHEDALYDPIVEDMFNNPEGQRHWDPLATGVTKEELKKKLMARWRNPSLTIHQVDVSGPKNRTVIPRSAKASVSMRIVPDQKVADITQSFEEHVRRVFGQLDTENEIEIDIKVVADWWLGDTEDRFFKAAESAIEQEWGQKPLFIREGGSVPAIRWLEKRLKATAVHIPMGQSSDQAHLNNERIRLQNLNSGKRVIKAFLRELRTLEVGPHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVY6</accession>
    <name>A0A9P6MVY6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UDENN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_010173</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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        <property type="evidence" value="ECO:0007669"/>
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    </dbReference>
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        <property type="entry name" value="Tripartite_DENN"/>
    </dbReference>
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        <property type="entry name" value="DENN DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12296">
        <property type="entry name" value="DENN DOMAIN-CONTAINING PROTEIN 4"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="DENN"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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            <end position="761"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="257"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="695"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="772"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1012"/>
            <end position="1104"/>
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    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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            <begin position="50"/>
            <end position="62"/>
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            <begin position="63"/>
            <end position="85"/>
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        <source>
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    <sequence length="1217" mass="134361" checksum="D54FAB66903AD396" modified="2023-09-13" version="1">MNSPKRIADYFYIVGLRDDTSLYPSDTNDGLPEHTDQHHHNQDKPARATVSHQTISNAGSPKQQLQQQQQQQLQQQHQQHQQLLQSQGPLQPKSVRPVSPKPTHDRRLSYAAIAAANIAGPPAATTTMTTADSIASRLPPSPLANSSAFKSPNRGRSQSMAQFHPPVVPAGFDKQETEGSPLRGPPATRPVPVRQSRRLSTASMVGPPRRPMTLINGNNPGNVVLQHKSNYRYVSAGTLYKAVQGGLDNEKTVDDIQDEHDTTSPNRQTRNELTEPAVRSNAAPSSDKQALSVQEIKSGALGRSNSTARRTKLPSGDKTPGIEEKKEIKPDVHPAERVFTPIVTCRYPETDWKDTEPFPTFLPMSESEIEYAKAIKSKIFLEKKLLKSLQLQLREEKTLGRRARQAQLQREILDSEEKLSLLGDQMKPWRGLFVEAEDAWIPRCIGLVSAVPYHYLLRDWLLGVVVACSGGVEHPGMSMSSFRLESYVKNLIHEVNLPPFGKVEIGITINNRMIYASRPALNSVPIVKNFSLFPLFRCLSAEDIVTVMEVILSEGKLIFVSSYPGMLTLASEGFLFLLFPFYWQGVYIPILPSALMTCLQAPVPYIIGIERRSRDAEFPPEEACVVDLDKGLIQVQLAPTPLPPRQRRKLIQCFEQYAPKSAIRRSADNPNPALGPPAYVKEAFPHSRFTMFCGASRAPRPSKSARPLSSIPYGGSSISQHSITMDPRGNGSTNTLPSLSSSELSKGDHVQQPLSYSKVAGGMARSASEGILDKGQDSLPKDGRSHRDALSRAESMKESSPTLQHSSESLRSTSSRKVFSPRSRSSMFEPRRQENASYEGAQSGHPMYNRQNSSNSTHMSIVGGFDGPGLRHRGSFTSIESSSSSVMSKSPVSATTSSTMASINGHSSPTASGALSSEDEAGTSSGADKAPPTVIEGHILSPVSSPIPISLLNCRCGFDESGVCWSVLQMWAGLMKGYRNGIIAGPGTQHYNPHSPLQPQHHQFQNYSARMQGHMKQLSNSGSEGEREGRDKLSWASFQRWTGRNGHGSTKNMMSPSSRASSDMERMHQSHPQRSQSSTQPRSRARSGTDCSNRSNRSNHSTHSEIVSFHRDLFLKGVDKEARPFMSVFTESQAFVQFVQDRIDRSSGDPEIMFFDEVIKAKNNRSKFRLGKEETKFLDDPSYGIQGTMRAIPPSGDIQLYDEDERRFPTTLDQAYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWA7</accession>
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    </protein>
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    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
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                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000571">
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    <sequence length="391" mass="43877" checksum="B3E34A6979FAA5FD" modified="2023-09-13" version="1">MSRQLYQPLSVPAPQFDVVNHPVKDTLVIVSTLLSILVHKNDSHYNPMRDPITLFHSRAVPRISIEAYLIRILQYIPFTNEVLLNVLVYLDRIGGLEGMQLQQGGALTSTTSSSAKTTGTTETTTAITMTKLMESSSTKNPEIYRSESSNPDLSLPVVQKRGRSDHEDVVESNDDNNNKRARTESVSSTSSSSSCASVIVPSTPVSTPPTPSLPLPSSNGFRINSFNIHRLLITCLMVGGLSLPELNQLELEFLFTTKFELNVKVDELQRVGNALFQFRDRHMARAVQQQQLQQQLQQRQQQQQQLCLQMQMRTQCQQQYSMPYATPSPKSPSPASSEVMSVPVQNSTDVRKSGFQEQKTQLLSPPEEKHSWAESEVHETHAQHIDEHFSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MX34</accession>
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                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000576">
        <property type="protein sequence ID" value="KAG0015994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
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            <begin position="18"/>
            <end position="40"/>
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            <begin position="72"/>
            <end position="97"/>
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    </feature>
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    </feature>
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        <location>
            <begin position="739"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="827"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="871"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="890"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="901"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="923"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="947"/>
            <end position="963"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="966"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="977"/>
            <end position="1017"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1088"/>
            <end position="1098"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1131"/>
            <end position="1143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0015994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1249" mass="134591" checksum="2EE519237A010E2C" modified="2023-09-13" version="1">MTGPGLVTLPIVAQSAGWLPTVLGFLVIGLLSTLSSLFICEAMTEVPGNEYFQSNVEFSNLVLCFFGRRSHLLVQIICFLAMQTTNIASIAVSVQLFDNLLIKIFNKTCGIQVYPNPAFICVTEQLAAASPFTGVMIMTTGVLLSLCMIVPLGLLKLSENIWLQLASFVLILLIMLEWIVTFCLEGLDTSLVPAVGSDISQTFGTILFNYAFITTVPSWANAKQPNVSIHKTVGWGVGITTTIYVAIAILGGMAFQIPSNSSLIQAITSSPDVSVLSQITGYTFPIAALITSIPINIIVIRYNLIQSGACNMLWANIFSGLLPWLVAIPCMTGSGLTAVINWSSLILVSAANFIIPFILYIYSKRHRERLNKLPIIEMEQQARLSRELSRSSSSGHSRRNTIASISGSIRRRLTGSNTHLRSPSHSDLTIGPQTGIAAASVIPITLGIGSGSLVYHSSEESLAGEASKGTNRRYHPHSPSDAGEHVSGPYFSFSRDGEPLEREPRTLNSTDQLGSRIQSSPHRQSGVATVILHDPGTETSQRKSALSQRISHKDKFLSLISDKHKRAMEQQAKRQQEEQSEKPVPPMILLSQSAAPELEDNPNSPLDIEIYAHQNDSYGSETCSEKGDMSQTKEIAETNDNLSTDIKNMNRKSSAIPSHSPKLSLSPSSPPTGFRGIGDSSSPRGDKADNTLELPSSFSPPRSPRSPRSPVSPKKPNIRWPPASPPGRGSPRADPVASRTATSPNLQLPPTTRVLHSAANIPSLDRRVSFSDEQPQLTPVSDLEHTPTFSSESKRVFKAAVASLAGGSPIHDTGDELSSPQEYKATLLEDHLEADKGGKGSNGKSRDEKEGRRGELGIDKKPSSLPNSLLRPDDIRRDSLGRMAAAFVSQPGSFSIKTTTLSLPSSSRSSSNKLSDLGSRQELNQRNREEPPHSSVSLEPSAPPTIQVDQNSGSRNRTVSASALQDGRDSAKEHNPRSPSAQSLRENVQRNQLAVPGSANSTNTHLTPHSPQRTTSPFLAVAENRDSSRSPTSSVPPSPLRLSRKNRSSDGGHGIRLSGNGKTLAAPFQSGNNYSIPGFGSSHSPSSPSHPLPSPVYPGYPGYPGQDQPMSAQGFGPSWINRRSHTRDPSRSSCVKSQWNGSIPPSPHPSLSDAMGVETPNGQSRQEFPMTPHSEVTNYSDPGKRLSLYALENGIAFDPMWSLRAIPTWIPVSSLKIAWGSLGILASIISATIVYDFVQLALGNDVVDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MX63</accession>
    <name>A0A9P6MX63_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">RNA polymerase II subunit A C-terminal domain phosphatase SSU72</fullName>
            <shortName evidence="9">CTD phosphatase SSU72</shortName>
            <ecNumber evidence="9">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">SSU72</name>
        <name evidence="10" type="ORF">BGZ80_009715</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB. SSU72 is required for 3'-end formation of snoRNAs.</text>
    </comment>
    <comment type="function">
        <text evidence="9">Processively dephosphorylates Ser-5 of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit (RPB1).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the cleavage and polyadenylation factor (CPF) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the SSU72 phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="9"/>
    <dbReference type="EMBL" id="JAAAID010000606">
        <property type="protein sequence ID" value="KAG0015675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MX63"/>
    <dbReference type="OrthoDB" id="57957at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005847">
        <property type="term" value="C:mRNA cleavage and polyadenylation specificity factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008420">
        <property type="term" value="F:RNA polymerase II CTD heptapeptide repeat phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031124">
        <property type="term" value="P:mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2300:FF:000039">
        <property type="entry name" value="RNA polymerase II subunit A C-terminal domain phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006811">
        <property type="entry name" value="RNA_pol_II_suA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20383">
        <property type="entry name" value="RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04722">
        <property type="entry name" value="Ssu72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 9" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5 9" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU369031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0015675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="191" mass="21886" checksum="BD481951D7967EBD" modified="2023-09-13" version="1">MVRFAVICASNQNRSMEAHNVLLKNGFTVSSYGTGTMVRLPGPTIDKPNIYNFGTPYNEVYQELKGKDTALYQSNGLLLMLDRNRKIKNSPERFQESKEEFDVIITCEERCFDAVCEDLIVRGESHSNPVHVINVEIKDNYEEAMVGGRMILHLAKDIEQARDLDQEIQPILDRFQQRYPNAPVLHSVSFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MX66</accession>
    <name>A0A9P6MX66_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_008534</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000465">
        <property type="protein sequence ID" value="KAG0017204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MX66"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018383">
        <property type="entry name" value="UPF0324_pro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30106">
        <property type="entry name" value="INNER MEMBRANE PROTEIN YEIH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30106:SF1">
        <property type="entry name" value="UPF0324 MEMBRANE PROTEIN FN0533"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03601">
        <property type="entry name" value="Cons_hypoth698"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="248"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="271"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="322"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="354"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="385"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="448"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="471"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="506"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="51"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="63"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0017204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="535" mass="58515" checksum="E5E886FCBC6951C4" modified="2023-09-13" version="1">MASGGYSARSQSTAFNGQDLADSVALNDLSTSAPFPPPLVSRDSMAISIASSSSNHTPNDITASDKENNKKKNQDTQKSDSQSPPKSRLHAFVRKHPWLVGWNHEDWWPCWIGLFLFGLVSVAVHNNIPAAKFAPWTVNPFDSLHGTNNLDLLVLFPLQGLLIWLALWALQAKNWNQFYKGFLVIYSLSFLSKMLASQRNIKSASLGDSIWAILFGTLLRNIMAGTPLPDGRSKSLPAWLKVAQQTELYIAISLVLLCIDFSVLKPLAPRAIFVSWIDTPSLFVLVALIGTTWLRIDLQTSMIMSAAIALSSSLGAGSKSDLPIAIISVFTIPSIIALPYIAKAVGISAKVAGAWFGGCVDSTGAVIAAATIYGDSGNVAVETSAVVKMVQNILIGPISVGVAAVWTQREERRMRALHNSLQDENLQSKPDFKPVPYKTLLWSRFPKFVLGFIVTAILFNTVVPAEDRADVNSFSFMVGEWFSTMSFVSIGLGLQFHELRREARLLLKLTTLYALAQLVDILSTFGLAYIAFEMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXB7</accession>
    <name>A0A9P6MXB7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Complex 1 LYR protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_009620</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the complex I LYR family. SDHAF1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000593">
        <property type="protein sequence ID" value="KAG0015804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXB7"/>
    <dbReference type="OrthoDB" id="273010at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034553">
        <property type="term" value="P:mitochondrial respiratory chain complex II assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20268">
        <property type="entry name" value="Complex1_LYR_SDHAF1_LYRM8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008011">
        <property type="entry name" value="Complex1_LYR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045295">
        <property type="entry name" value="Complex1_LYR_SDHAF1_LYRM8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13675">
        <property type="entry name" value="LYR MOTIF-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13675:SF1">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05347">
        <property type="entry name" value="Complex1_LYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Complex 1 LYR protein" evidence="5">
        <location>
            <begin position="13"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0015804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="83" mass="9754" checksum="69EB09F06516BCC5" modified="2023-09-13" version="1">MSGVSVRRSGLQQEVLGLYRQCFRAARLKPEANRPHFHAFIRMQFRKHSEVKQRDFSTIEYLLRTGKRQLDVYSSPSIEDVTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXE7</accession>
    <name>A0A9P6MXE7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF937 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_009025</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000511">
        <property type="protein sequence ID" value="KAG0016691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXE7"/>
    <dbReference type="OrthoDB" id="2438364at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0016691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="343" mass="35763" checksum="AB793BB738BF3FAB" modified="2023-09-13" version="1">MDKLVPLLMNVIEEKARPHVQAKVTEELDSTKVDLKEDLPDTIIKFLSGEDGNGGGNPLVGQIISKLGPSFTRRLTSVTNTTVDTASEGMDILLTNGVINIAKKVLSNQVDGADTDSREVGGLNFEVIKSGKEGMVKTTMAASAPVIKQVSDNMGNKISSSFPAVVGGAVQQMIDENGGEHGLMGMAAGLMTKLMSNHGHGDRAVGGGGERVVGGGGDVSDIRATGGHTGGIQEMLQNLLAPKILLLLQPYLQKFEAKMTESLEKELRTKVFSSEYIKQTVVAMLTGAHGEGASGSSALIGGIMSALGHGGKEGKEGKSGQTIEALSNLASSFLKHKSKHSGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MY53</accession>
    <name>A0A9P6MY53_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_007385</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000377">
        <property type="protein sequence ID" value="KAG0018262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MY53"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0018262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="133" mass="15043" checksum="757F6E6E731C834F" modified="2023-09-13" version="1" fragment="single">MISDLNPGCLEVMVGVEEDGGREFGAAVKKSSHVMNLVVRRAALYAPVLSHRRKMEALKSQTICVNPRQHIGGRLRDQRRWYECQGRLPSVKEIEPELLPNDYVTTEELATALKRWHLVDTVLRGFCGSEKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYU4</accession>
    <name>A0A9P6MYU4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_007767</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000403">
        <property type="protein sequence ID" value="KAG0017922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYU4"/>
    <dbReference type="OrthoDB" id="10265110at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016765">
        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="entry name" value="UbiA prenyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="74"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="121"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="244"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="268"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="307"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0017922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="340" mass="38028" checksum="D1B62F30EEEE5CA1" modified="2023-09-13" version="1">MKKELESKSEYSGSSSSSSRQVEIFVQFSGFKSWFKFFSERIALFVYLLTAAGYVLTANYALSDGSKSLPLRPFFWTLVIETLFLITLRVMDDLKDVDTDILAHPERPLPRGLVTAREASIVVHGLVSILIINGIVLAIVENLACGLLCIATTLYYYAMFKEFGCGHWLSARPILYVISHQLVVLLMVLFPVAAFHGASSLKSILCWHAALLQFCGSFTFEVCRKLDPTAHVALGTYLIAYGKFKTFLMILFAVAIGAWASYVMAVEIIMWPFLGFLLLTVLILFWKQRTPGTPLEKDEAPPKGHKIVELICTLITLLTMYIVPIKIWSGVPKAAMRTFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYW5</accession>
    <name>A0A9P6MYW5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">6-pyruvoyltetrahydropterin synthase</fullName>
            <ecNumber evidence="4">4.2.3.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_007817</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; tetrahydrobiopterin biosynthesis; tetrahydrobiopterin from 7,8-dihydroneopterin triphosphate: step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PTPS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.12" evidence="4"/>
    <dbReference type="EMBL" id="JAAAID010000408">
        <property type="protein sequence ID" value="KAG0017871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYW5"/>
    <dbReference type="OrthoDB" id="14045at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003874">
        <property type="term" value="F:6-pyruvoyltetrahydropterin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006729">
        <property type="term" value="P:tetrahydrobiopterin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.479.10:FF:000003">
        <property type="entry name" value="6-pyruvoyl tetrahydrobiopterin synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.10">
        <property type="entry name" value="6-pyruvoyl tetrahydropterin synthase/QueD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007115">
        <property type="entry name" value="6-PTP_synth/QueD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038418">
        <property type="entry name" value="6-PTP_synth/QueD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12589:SF7">
        <property type="entry name" value="6-PYRUVOYL TETRAHYDROBIOPTERIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12589">
        <property type="entry name" value="PYRUVOYL TETRAHYDROBIOPTERIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01242">
        <property type="entry name" value="PTPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55620">
        <property type="entry name" value="Tetrahydrobiopterin biosynthesis enzymes-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0783">Tetrahydrobiopterin biosynthesis</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0017871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="145" mass="16477" checksum="1CAF61D8750F21C2" modified="2023-09-13" version="1">MTSSTLRMAYVTRIEHFSSAHRLNSVHLTPAENLDLYGKCNHSSGHGHNYKVEVTIKGQINPQSGMVINIADLKKTLQVAVMDPCDHRNLDIDVPYFQSIPSTTENLAVFLWENINLHLPPSKTYSLHEIKLYETDKNVVIYRGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZ91</accession>
    <name>A0A9P6MZ91_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cytochrome p450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_007766</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000403">
        <property type="protein sequence ID" value="KAG0017921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZ91"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF166">
        <property type="entry name" value="CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="2">
        <location>
            <position position="424"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0017921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="482" mass="55451" checksum="7BECF7053711887D" modified="2023-09-13" version="1">MLTLYDWAMEYPGLIYRYYWFTRLTLMTSDPITVGYVLGKANDNWLKSKGTEEMFEQNLGHSLLTMRGREHTSHRKYLATGFKHNYLKSMTNAFQRRVEDLIEVWKERLPAKQQKYEDSKEARWVCDGNIYTTIDLEPSFYCLALDSIGEFALGRSFDAIKRPIGPDFENYRIIVDSFKVTLLSMLPFSNWLPTKTNRRAWSAVREFRASMAKIVQEQKEVLIKEIEANDGKFSEEEGAPSQKKDILTMLLVDQLTGEGCSDSQIQSDVFTAIFAGHETTSAALSWTFYQLACHPKVQARLREETRKLYRNTDGAPSYDELNSLPYLNAVIRESLRIWSPVPLNLRVSVEDDYLPRSHGLEPLFVPAGTNLQIPMFILQRDPKIWGSDSLQFNPDRWISGGPCPPYMPPHGLCYFPFYYGKRSCIGNKVATLEMKVHIANLVNNFEFVQTPEMKDNFGEIDWKWSVSLKPSPGVCLGVRLAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZB0</accession>
    <name>A0A9P6MZB0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ribosome production factor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">RPF1</name>
        <name evidence="3" type="ORF">BGZ80_006754</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000335">
        <property type="protein sequence ID" value="KAG0018779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZB0"/>
    <dbReference type="OrthoDB" id="264354at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042134">
        <property type="term" value="F:rRNA primary transcript binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000460">
        <property type="term" value="P:maturation of 5.8S rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000470">
        <property type="term" value="P:maturation of LSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10480:FF:000002">
        <property type="entry name" value="Ribosome production factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10480">
        <property type="entry name" value="Probable brix-domain ribosomal biogenesis protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007109">
        <property type="entry name" value="Brix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044281">
        <property type="entry name" value="IMP4/RPF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22734:SF3">
        <property type="entry name" value="RIBOSOME PRODUCTION FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22734">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN IMP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04427">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00879">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50833">
        <property type="entry name" value="BRIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Brix" evidence="2">
        <location>
            <begin position="94"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0018779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="299" mass="35190" checksum="03D7401C8A8B2BD4" modified="2023-09-13" version="1">MVEINTIKNKLKREELFSKQKAAKAKQKRDRRIAQKKEEEANPEKKEKRLAENVPNTLENTREFDETIVEEDEEVAADEATDEFSQYFQNGVAPKILITTSKGPSASVYEFATELIDIFPNSHFVKRKPQFEMRHIVEFSKNRDFTDIMVINEDKKEPNALTLIHLPDGPTAHFKLSSISLSKDIEGHGRTSSHKPELILNNFNTRLGHTIGRMFTTLFPHVPEFQGRQVATLHNQRDFIFFRRHRYVFKNAKRVNLQELGPRFTLKLKWLQKGTFDRKGEHEWMFKPEMETSRRRFFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N089</accession>
    <name>A0A9P6N089_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AAA-ATPase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004652</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000235">
        <property type="protein sequence ID" value="KAG0020179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N089"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018631">
        <property type="entry name" value="AAA-ATPase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34825:SF1">
        <property type="entry name" value="AAA-ATPASE-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34825">
        <property type="entry name" value="CONSERVED PROTEIN, WITH A WEAK D-GALACTARATE DEHYDRATASE/ALTRONATE HYDROLASE DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09820">
        <property type="entry name" value="AAA-ATPase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA-ATPase-like" evidence="1">
        <location>
            <begin position="138"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="604"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0020179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="604" mass="67656" checksum="6C016AC64B768F4A" modified="2023-09-13" version="1" fragment="single">MLSAGLLRAQGVRTLARVNSRSLQFPQMLSRSLKVICMIDGADNSFPVEIDDEADTLTLYKAPVGVRFTEPGVTVGAKDEIKTISSLRGIITDANRVHVIVRPPSYKRSPLNVVQYNRRSGDLVWKDDTFKSFPVGHISNFKTLRQRPDLCYFDKTAFISALEPVYCDALVFLRPRRSGKSLALSTLAHFHGREHLPDYGPLFEGLAIHEHVTKKRVSPGQYFVLQPDFSAATRTPDRDDAWHNLSVMLNESIKQFYRTYEPYLRESADYLIEKFIQSDPVANEYDSFSYEYLASVDSVQWKPPRKPSPSGLLRGFWALVKSELDDRKIAKCYMAGVSPQSMDGDTSGFNVDHSVSWDEDPAGLCGLTEADVTATLAMEQVCRSTVEAGKHLETMRDHYSGFNFVPDEQGPLAYDTNTCLEYLQAEHIARDRAVWLSLMVHLGGLTFCVGKEGLRIPNLVAAARLGRAILDRHHASLEDVNGAFKALIDNGCIDKIIGLYARGMQQHDVGHRNFLMKEEDYCNLMRSILLGNIHPSLRKFDVETTITKSIQIYNLEIGSGSQSIKADALAKILDTTDVLNLKFGHRESSQSIKDWILSGPKVGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0C1</accession>
    <name>A0A9P6N0C1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Chromatin assembly factor 1 subunit a</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_006171</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000303">
        <property type="protein sequence ID" value="KAG0019207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0C1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033186">
        <property type="term" value="C:CAF-1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021644">
        <property type="entry name" value="CAF-1_p150_acidic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022043">
        <property type="entry name" value="CAF1A_DD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15272:SF0">
        <property type="entry name" value="CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15272">
        <property type="entry name" value="CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT A CAF-1 SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11600">
        <property type="entry name" value="CAF1A_acidic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12253">
        <property type="entry name" value="CAF1A_dimeriz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="2" id="KW-0235">DNA replication</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromatin assembly factor 1 p150 subunit acidic region" evidence="8">
        <location>
            <begin position="449"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="domain" description="Chromatin assembly factor 1 subunit A dimerization" evidence="9">
        <location>
            <begin position="672"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="454"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="713"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="29"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="104"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="713"/>
            <end position="769"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF11600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0019207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="836" mass="92872" checksum="558B7D17DCF0DA47" modified="2023-09-13" version="1">MPATNASESAVNTTSPEKPKARKRISKVKAKETSENKHPTSTNKDATVLEDAPPKASPNPKGRRTKSEFVTSVSVPMMQPRVSKSQVDGADKSTNPTPSPFLTDSKDAPRSPIKETATSTVVTNSAAGGSSSNTSKLNKIDTASMFKVRSGKAYITENKLKFSAHPSAIADLCRFHEYREKLREAQELSQYPGTRLEADHVEIMSIPEEHYGLIAKLVEESELALTEMATGILAMLCPLGFETFKDMTETQEAHNGGEKMDVDVDTVMKDGEDGQTFVRNNTTVTIAAIVEAIQSVATRINYGIPVSSLPGPVTMTPANLSVYRWEVQDIDRYFPNDMKAVVLKRRGKRMEASAALTAWFLGLDLKQQEDLCPIPVVPINALGTSLVTENGQLAAGKKNESMDVDGDMVKLTGAATDGSSINKSGTILLQGQPTVAAALDPAILESKLREAEAKKKEAEAKEERRLEKERRMAEKQLEKDLKEAERIQREEAKRRKAEEERLKKEQASCYQFVGFFKPITSSAVKKDGSQACVKSDIAASSLSELFHPFHVKKNTVLAPVNRFAKNIHRDIMDKELHIKGSSEECSDMDIDLEHGVPMMVEKTITKETVRALFPRTQRSEDSATRQTKKKLPQRYQSMTVTEVVQSGLLLQDEDDDTNYMLTWRDIPSLRMRLLQFAENYRPAYYGTWSKQSKSISGRRFLGKDTELIDYEFDSEAEWEEDEEGEECKSDDDEEDAEDLGSDQDEEDDWLVPEGYLSEDEGLDAGEEGGSEAVSQKKSKEPRRQTLAQMVPIIVGPIFETTLGESSHPALEPYRVEFLGDYGVGMDMFHVVENSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0J8</accession>
    <name>A0A9P6N0J8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_005639</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000278">
        <property type="protein sequence ID" value="KAG0019538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0J8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0019538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="651" mass="74951" checksum="01F93D9D786B8639" modified="2023-09-13" version="1">MTIVTHPSAVFTLPEILEYILSFLTRNERKNAARYVCKQWFYICRSLAPPRPLVWYPNWKDQDGAKTLQALGGAGILRLMSWADGPGDRVFGTHIMDPDTKSRGWERLLSGIELQLQQSQGLLPLQEIELRHDFTEPVYFNQILPLLPQFSFLSTLRMYTTDGPPDRVLLHSVLSTCSNLKVLIVAGPETPKRDCLHDASKEYFCSRERLSSITPLPMLRRLKTLTINNALLSRGTVESIIEASPNLRSLTILQAFTIPQSWQDTIDVGTTGAIDLRPVFDRMRFFQLMEAVWLNLQRFHLSVRNDLLSTQEFMVFMDSRVSRLPVWSFSDQELQPGYPLHKLFFSTDPLILRNHHQRLTSLELVRTPKGRMQSEGALHHFLCEATHLQNLRAINVPIDIESLDVNRLLVKRRFKDGSKSDEQILYEQQESEQQLWGQGRPRVWACRGLLTLHVTLETRDFLYPEPVSKLPVSSQIVFGYISKCCPNLKEIHLRRQHSEMSRGSGFCLLSRLRYLERLMLMGETFLNLKIKELAWLGSQRYRYPSSVNDGDMLSSGRQESDVDLCKLGLPSDINAWTKESRQRLWGMFSRKGNSNEGKEGVCWPRFESLKITYVRGQMGSAESIDAMQIQGLMHINWPGVMVDFEIARSYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N174</accession>
    <name>A0A9P6N174_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Synapse-associated protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">SYAP1</name>
        <name evidence="3" type="ORF">BGZ80_002613</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000165">
        <property type="protein sequence ID" value="KAG0021338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N174"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038203">
        <property type="term" value="P:TORC2 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3970.10">
        <property type="entry name" value="BSD domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005607">
        <property type="entry name" value="BSD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035925">
        <property type="entry name" value="BSD_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051494">
        <property type="entry name" value="BSD_domain-containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16019">
        <property type="entry name" value="SYNAPSE-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16019:SF6">
        <property type="entry name" value="SYNAPSE-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03909">
        <property type="entry name" value="BSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00751">
        <property type="entry name" value="BSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140383">
        <property type="entry name" value="BSD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50858">
        <property type="entry name" value="BSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BSD" evidence="2">
        <location>
            <begin position="210"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="277"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="317"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="44"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="283"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="335"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0021338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="431" mass="46942" checksum="886A50245B988CEE" modified="2023-09-13" version="1">MDKTLAETAAESRAPEGSMPTAPKDSADHSVTTQDSNQLEKDANQQQEQQQQQQQPAQSFAAAVFPGFNPPKINTSSFFSSMSSMQGKIQSTLANAKSPTLNLHAPHINKVDVKQLQASTEQLANTTKDWGINAFKSLSGAAQRVSANVTQGIQKEHEEFVKQKKLETVVPHQGTESLPAWAGMPDEEKIKARILSLSKDKRNFLLPPPLGNDFIFDMNVYSSTAVATLKADPNLEKMRFYLVPKEVEELVFWRNYFYRVSLLKQFALAAAAGGPDSLAEVQSGSTTEDGTESSKGTGNGRPLSESSALGYNIYFGKDDIEGPPKRSRPTSVINKDPNTTSTSSTTSVAAKDTAAKDTTAKDTEKAPAKKQEAKPEVLFEAEMPAHDEDPDAWLEKQLASGVSIGDDDADVDVGDWEKELQNELKDYVEAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N185</accession>
    <name>A0A9P6N185_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein YAE1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Protein yae1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_003441</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the YAE1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000191">
        <property type="protein sequence ID" value="KAG0020869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N185"/>
    <dbReference type="OrthoDB" id="20086at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019191">
        <property type="entry name" value="Essential_protein_Yae1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038881">
        <property type="entry name" value="Yae1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18829">
        <property type="entry name" value="PROTEIN YAE1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18829:SF0">
        <property type="entry name" value="PROTEIN YAE1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09811">
        <property type="entry name" value="Yae1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Essential protein Yae1 N-terminal" evidence="9">
        <location>
            <begin position="53"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="161"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="17"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="168"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="178"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="201"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="215"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="246"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF09811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0020869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="285" mass="30959" checksum="011E281C02D5BA85" modified="2023-09-13" version="1">MADLDQHSNHSSANAQEDSDSGDIWDDSDNISHDRAIAERDWSRMNNTFGNAGYRDGIEEGKEGTLQQGFNQGWSEGVHYGYELGRLRGLISPLLEYLRSTPSSSTSTSNNNNNQLNKIQDKDEWIKKASELVKELTLLDIDKIFDKAFFDDKINISSSASTSTSKSLVEDSTRGDSTRSGCCGGSSSSSSKDSCCKNEATESSNMSSSDHQGPSSSEGSCCSSKNGHDSSSSDGCCSKDKKINDPNDNAGNVWSSRPEQVISSYRSRVEELLKEVGLQSLLDLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1J4</accession>
    <name>A0A9P6N1J4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Vacuolar protein sorting-associated protein 17</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">VPS17</name>
        <name evidence="3" type="ORF">BGZ80_002938</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000175">
        <property type="protein sequence ID" value="KAG0021176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1J4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030905">
        <property type="term" value="C:retromer, tubulation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032266">
        <property type="term" value="F:phosphatidylinositol-3-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053055">
        <property type="entry name" value="VPS17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015404">
        <property type="entry name" value="Vps5_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47433">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47433:SF1">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09325">
        <property type="entry name" value="Vps5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PX" evidence="2">
        <location>
            <begin position="205"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="567"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0021176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="597" mass="65893" checksum="D07B62FF5CEB6D91" modified="2023-09-13" version="1">MAQDFSDPLTSAAYASSKIESGSDPLRAPSPVPAVVQQPNPPVKSKSITTQSGYDPLSSPTIKKPTTQSRTTPPASSTRQKHIPPTPSKAPATGVNPKRFSEVSSSSSPSSPKIQPFSDPLSSNSSEYEPPYMDQSSYNNSSSKGVTNVSQRASIASFPGGSKVSKASSTANRVPNSSPSSPIPTEKAVPPAQRRESSYDHQRIKAPQYLHITIPDTDRRGKDGMFLISVQTNMPRYKRQSYQNVTRSYLEFARLREHLVAEHPEVIVPVLPPERSLVSASDIQLMRMFLERVGRHPTLSQDHELQMFIESEFGFLPPVKSNKILGKLLNISVKRFSSGGSSAPSLGDTDDEFEEERVVATKLDSKLQVVMKCLDKEIKARRDYSSRESELATLSNSWAASEESPELSRAFKMLAKPLDGMAKASKAQVGGDATVLGSYLEYKLQHVQTLSGALDYRLSVLSEYDSAIKSTESKRKTMERLRSSTSINPEKVTDSIDDLEDARIVEGNMKKRMEQISSALAKDLEGYKQQSQEDLLRVLQQYSQRQIGFERAKLEELLSVSARLRIDHDRSEETSRPASENDYLRGESSFVGAVPPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N220</accession>
    <name>A0A9P6N220_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein SCAI</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_000530</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000111">
        <property type="protein sequence ID" value="KAG0022331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N220"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022709">
        <property type="entry name" value="SCAI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21243">
        <property type="entry name" value="PROTEIN SCAI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12070">
        <property type="entry name" value="SCAI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="321"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="325"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0022331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="604" mass="67281" checksum="E96171EC9BF19FB1" modified="2023-09-13" version="1">MESPSAPLQQSPSSTNPAPVPSIPAAANNPPSTNPPNNGPTADTVPMEDVVSTNAVTAEVIARQNQAVVEEFQYLLEKSQQLFAGLRDLPPTGAKQWQPYFQKTFEVFSKNLCLVSLRHPIKLWRFQQQNRFVLENSYGLKRWEVGEIASKIGQLYYHYYLRTSETNYLQESYVFYDAIRERRYFSEISDIKRQVKRLLLNNRDNVSTLKDELAALVKEYIAVYRPPDAAEWQLVVQEVSSFTDAERKLHPVNAAGSYLPVARRLHVSKIISAALDKEGSSSTKLRLQEAILVGNAHNQIKFSELTIDMYRILQSLERETSQIRSTSDTTTKDASSNPATAATTAVTNDGGTNIPIKEEPAEDQSVTVRRNTEKGTKRLNPHKYLLYRPTLSQLMVYLATAFKEVSSDSALLIYLSADGSKRSAADHSGTKGYHGGILTNSRKVADNTDPEQQSISHCLHPGDLLPFTRKPMFLIVDSNNSVAFADMPRVFNHPFMSLLSPTEYPASIPDTSQVGGLFTLFLHAPLLAFSFICGIDQISPDTWEQCSGLITQAEGKIAELMATAPLGNKKQPFLISVGGSYCRPLNFNSTFKLHRQTGEKVPTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N248</accession>
    <name>A0A9P6N248_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Anti-silencing function protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ASF1</name>
        <name evidence="8" type="ORF">BGZ80_001164</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ASF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000126">
        <property type="protein sequence ID" value="KAG0022059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N248"/>
    <dbReference type="OrthoDB" id="29755at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006335">
        <property type="term" value="P:DNA replication-dependent chromatin assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1490:FF:000001">
        <property type="entry name" value="Histone chaperone ASF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1490">
        <property type="entry name" value="Histone chaperone ASF1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006818">
        <property type="entry name" value="ASF1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036747">
        <property type="entry name" value="ASF1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12040">
        <property type="entry name" value="ANTI-SILENCING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12040:SF0">
        <property type="entry name" value="HISTONE CHAPERONE ASF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04729">
        <property type="entry name" value="ASF1_hist_chap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101546">
        <property type="entry name" value="ASF1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0022059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="191" mass="21861" checksum="FA8B13E297BE5203" modified="2023-09-13" version="1">MSIVSITQINVLDNPTHFANPYQFEITFECIAPLAADLEWKIIYVGSANSNAHDQVLESIMVGPVPVGVNKFVFQADAPKPELIPHNDIVGVTVILITCSYQDREFVRIGYYVNNDYLEEELRENPPEQIAYEKLYRSILAEKPRVTRFPINWDNPMEEEQPPLQTEEQIEEMEAATKAQLEGGEWEDMES</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2A7</accession>
    <name>A0A9P6N2A7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ADP/ATP carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ANT1_1</name>
        <name evidence="11" type="ORF">BGZ80_000036</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000100">
        <property type="protein sequence ID" value="KAG0022532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N2A7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015217">
        <property type="term" value="F:ADP transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052217">
        <property type="entry name" value="Mito/Peroxisomal_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45939:SF1">
        <property type="entry name" value="MITOCHONDRIAL THIAMINE PYROPHOSPHATE CARRIER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45939">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PMP34-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="72"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="114"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="208"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="7"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="111"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="205"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0022532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="314" mass="34510" checksum="BE04EA01965CD0CF" modified="2023-09-13" version="1">MAGGSKLSPFGHAIAGTGGAMFALTCTYPLDIIKTRIQVRSRNASEASDPDVYVSTRDAFQKILKSEGVMGLYAGLLTGLLGTASQNFTYFYWYTLIRSGYINRLPAGDSLSTAMELLIGAGAGALTQIFTIPVSVVTTRQQTMPLGERQNLRDTAMDIVEEEGWTGLWKGLKPSLVLVINPAITYGMYSRIQELVLKAFRRKDMTPGLVFLVGALAKTLATVVTYPYIMAKVRLQWKPSKKDAATHKPYKGAVDVLQRVFAKEGLKGWYTGMQAQISKAVISQALLFMVKDQLEKYTILLFALLAKQNRGKVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3B5</accession>
    <name>A0A9P6N3B5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MIF4G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_000813</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000118">
        <property type="protein sequence ID" value="KAG0022182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3B5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035145">
        <property type="term" value="C:exon-exon junction complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.180:FF:000037">
        <property type="entry name" value="Nonsense-mediated mRNA decay factor (Upf2)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.80.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003890">
        <property type="entry name" value="MIF4G-like_typ-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039762">
        <property type="entry name" value="Nmd2/UPF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007193">
        <property type="entry name" value="Upf2/Nmd2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12839">
        <property type="entry name" value="NONSENSE-MEDIATED MRNA DECAY PROTEIN 2 UP-FRAMESHIFT SUPPRESSOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12839:SF7">
        <property type="entry name" value="REGULATOR OF NONSENSE TRANSCRIPTS 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02854">
        <property type="entry name" value="MIF4G"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04050">
        <property type="entry name" value="Upf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00543">
        <property type="entry name" value="MIF4G"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MIF4G" evidence="5">
        <location>
            <begin position="11"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="MIF4G" evidence="5">
        <location>
            <begin position="499"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="domain" description="MIF4G" evidence="5">
        <location>
            <begin position="707"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="236"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="406"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="936"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1138"/>
            <end position="1180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1204"/>
            <end position="1227"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="1089"/>
            <end position="1116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="103"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="242"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="406"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="433"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="938"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="948"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1157"/>
            <end position="1166"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0022182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1227" mass="137756" checksum="D77A3BFEC053833C" modified="2023-09-13" version="1" fragment="single">PSALKNLDSNIKKNTGFIKKCKTGLTADVSAQLLNDIKKLSLEKYISEIVTAILEGLLRCKLSVDVAAAVEVISALHQRFPDTFTLLFTHHLAKALAPSPKLSHQQLAQAGSTPEQREKEEASRVSRQRILCRVATDLWLAGVLRNVEDGVAALNTEGTASVSSKSGQASKDSVAGLLINQNKDSKGSISADTSKSFPTFIYTILHDLLAGDKDHVNLPILLTVLKIHGKDLTGIVPRKSKASGEGKDSDSKPSGVEEAAVAPSDNIVSPPQQQFFKTMFVEYYKALESHLVHDHKELKKQERKNEASLFSRGELSEERQQQFEKQFKAFEKLSTSTQTVADALDMDMPILKDEKEDLIGIVESTNGSEEKGASSSVFEDEDSIAFYEQILDLRTLVPKLFLESSKSKKDKKDDGNDADKDGEKTAGKDELSSTEADSGSKGTDQLDDLDESADLIMENLDAELDDMDVNDATGTESFLKEETITTIQESTGTASKTTATQLDAFMAKLSSMCNRDMIDQAAVDFCYLNSKLSRNRLIKTLVQVPRDRHDLLPYYSRLIATFKPFYPDVAEEVLAALEREFRGLLRKKHLDLSESRVKNIKFLSELVKFGVTPLPIIFHCLKVLLEDFVPQNITVACALLETCGRFLKRKSAATSARLDTMLEILKRKKAALHLEPRFLLMIDNAYYQCNPPEQKTRQKREIPPMEQFVRKLLYLDLCKKNVETTHKLLRKLDWNDKEVYNLVLRLFSKVWKIKYSNIHLMAILVNGLSRYHSDFSIAVVDSVIETIKVGLEQNNFRHNQRRIAVVKFLGELYNYRMVDSPLIFSTLDTLISTGHEQGRASPDRPSPIDSPTDSFRIRLVCTLLDTCGMCFDHGSSKIKLDSFLVLFQMYILSKESIPLEIEYMIEDTFTELRPKLRRFLVYEEALAAVEALHGPLGSNDQASMIQNDDSDSEDSEGDDDGDDDNQDDDDDETDDEDEGLDDDEEIHAMRQADEEEQAVVLTNQHKPIEAIDEVFEREYLKMMTESLESRKFERKHMTLDVAIPILRSADRREEPESNNPDHVTFTLLTKKGNKQQLKTVGLPSDSALVINTRNQREAEREEQQQLKQLVLEYEVREEANQRAALEQSLRNQGIRLNFTEDNRRGVGGAGSSGRDPNPPRHDRVDRAGFGPDPIKNNSRWARNQAVGVGAGFGTESALTNLGVDGYERRPVGGQANRGRGSGNYVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3D6</accession>
    <name>A0A9P6N3D6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Kinesin-like protein Klp8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">KLP8_1</name>
        <name evidence="16" type="ORF">BGZ80_001203</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000127">
        <property type="protein sequence ID" value="KAG0022036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005546">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008574">
        <property type="term" value="F:plus-end-directed microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047496">
        <property type="term" value="P:vesicle transport along microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd22705">
        <property type="entry name" value="FHA_KIF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01365">
        <property type="entry name" value="KISc_KIF1A_KIF1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01233">
        <property type="entry name" value="PH_KIFIA_KIFIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.200.20:FF:000021">
        <property type="entry name" value="Kinesin family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.850.10:FF:000047">
        <property type="entry name" value="Kinesin family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2520">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022164">
        <property type="entry name" value="Kinesin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022140">
        <property type="entry name" value="Kinesin-like_KIF1-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032405">
        <property type="entry name" value="Kinesin_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049780">
        <property type="entry name" value="PH_KIFIA_KIFIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47117">
        <property type="entry name" value="STAR-RELATED LIPID TRANSFER PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12473">
        <property type="entry name" value="DUF3694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12423">
        <property type="entry name" value="KIF1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16183">
        <property type="entry name" value="Kinesin_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="8 10" id="KW-0505">Motor protein</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Kinesin motor" evidence="15">
        <location>
            <begin position="1"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="domain" description="FHA" evidence="14">
        <location>
            <begin position="498"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="13">
        <location>
            <begin position="1537"/>
            <end position="1635"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="990"/>
            <end position="1021"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1146"/>
            <end position="1166"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="687"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="991"/>
            <end position="1005"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1150"/>
            <end position="1166"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="107"/>
            <end position="114"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0022036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1641" mass="185386" checksum="235329BD82CDC691" modified="2023-09-13" version="1">MHAPARVSFPNGSKSFAFSFLDSARAAIETAEIAKQSECIIQMDGNMTSIRKPEEGTTKSFSFDHSYWSFDKNDPNYAGQQRIYDDLGVELLNHSFNGYNTCIVAYGQTGSGKSYSMMGYGEERGIIPLSCHELFRRIEANKDPSLSYRVEVSYMEIYCERVRDLLNPKNKGHLKVREHPSLGPYVEDLSKLMVTSFRDIENLMDEGNKARTVAATNMNETSSRSHAVFTVLLTQKRHDSETRLDTEKVSRICLVDLAGSERANSTGATGARLKEGANINKSLTTLGKVISALADASNPAMAAPKKGVLTWLLKDCLGGNSKTTIIAALSPADVNYDETLSTLRYADQAKRIKNKAVVNEDPNAKLIRELKEELQDLRSKLNIYDPTNFGADSKAPNDLVTIVDHNGNAKTFTKEQLQDEVQASEKIMAELNETWEEKLRRTQEIQQEREKTLEELGISVEKGHIGVHTPKKMPHLVNLNEDPLMSECLVYQLKPGNTVVGRLDSSVPADIRLSGANIQDAHCYFENNNSSVTLHPGKTSVTMVNGLRIHKPKKLRSGFRVILGDYHLFRFNHPEEVRRERDSQLHQSSVQSELADWNYARKEAVIHAHMLSESNINQLKNEDLDVLYDNIAKIRYMRKSGRSESRAGSNFDDDLESRSSKLSFNGRWHGEGIDGRESPVPPLESSALALKERLRQAEEEMQKMTQQKREYESKIQNLSAAEAKSDELLAEKALMEDRLRQAKEDLAKQLELQKVQYEDKMKRLSLTSIASHHLDESQLKGKLLLPLYSDFELRVIHKTLKRWKEQRSVQMAEAIIANSKHVKEANVCSRELSKNVTYQFTVIEGGPFANPTSFWESPSGLSQFTNEEETSLSDLKRPCIGIKVIDNKHHSIYIWPIEKLVARIPRMRNLYEFSDRPQQYRKQSNMEDPFYDAPCPRYTFVGSASVALRSLAEMQFAESVVPILCRTTGKITGRCRVGLTPLSLSDAKSRAALSPASSTPNSPTTRVSSRNASRGHSRERSRLSNKIEVLQSSVGVGDQLLFEVSILSIEGISEEQYTQVHAQFRLSNFGGVVPRSPSDKVYATDFANRFEDKSIFFGFTQSLSIIITQPVLDVLMNKSLNIEVFGLAKDATLKAWDKWDQDQEAASRLPLQSPTQKNGFLTASVDNTNGRASLESINSIGERRSEDGQSNEQKHDVLAFIKLCELAPDGEYMPVRVISDDVMDPGAFQLRQGLQRRIVLTLSHASGKNLPWNKVTNIQLGRVRLVGGKGNVTESTPPHDDVTLNLIPGQKVEYLRNGASELTVQASWDSSLHDSLFLNRVTTANTRVVMTITWLVEVDNCPEPIRFQMDIPCQIQDREARAPSMFTTFLTSTRTLTRMSGLFLLTLKPIVVKNLTDLWKTSTKTEYVRGEENLKGWTPRGLSLVSGFRARTNLINNQEEVERTRQCLQLRGVFVQNGANGSTVTSKEAGLDSEAHDELDERSRQLLQKMVKLWTRKRITVEELLSNQPAEEIEAAKLSRPPTRYQSEAKLVTKSENMSKKGYLHYPEDNDDVWVKRFFVVRRPYMYIYASNSEMEELAVLNLTNVKVGYKQHDEEMLDRQFVFSIFTANNAYLMQASSREEMCSWLKQLDQFFDLSQIPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3H4</accession>
    <name>A0A9P6N3H4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_007729</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000040">
        <property type="protein sequence ID" value="KAG0023855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3H4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004467">
        <property type="term" value="F:long-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272:SF33">
        <property type="entry name" value="AMP-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0023855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="143" mass="16098" checksum="21983B361E494780" modified="2023-09-13" version="1" fragment="single">MAIEQKLRSVELPGTRRPGQTGIYRRTGFENKPLLTSPPTFPHVTTIYEAFQNGLRISPHGPFLGTRQYDPVTKTFGGYVWQTYTEVSDRITRFGSGMVKIHQDVHQLAEPAQRWTVGIWGINRAEWTISSEACSAYNLATVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4E4</accession>
    <name>A0A9P6N4E4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">polynucleotide adenylyltransferase</fullName>
            <ecNumber evidence="5">2.7.7.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BGZ80_009003</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DNA polymerase type-B-like family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.19" evidence="5"/>
    <dbReference type="EMBL" id="JAAAID010000051">
        <property type="protein sequence ID" value="KAG0023570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N4E4"/>
    <dbReference type="OrthoDB" id="2274644at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990817">
        <property type="term" value="F:poly(A) RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010605">
        <property type="term" value="P:negative regulation of macromolecule metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031123">
        <property type="term" value="P:RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05402">
        <property type="entry name" value="NT_PAP_TUTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054708">
        <property type="entry name" value="MTPAP-like_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002058">
        <property type="entry name" value="PAP_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12271">
        <property type="entry name" value="POLY A POLYMERASE CID PAP -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12271:SF40">
        <property type="entry name" value="POLY(A) RNA POLYMERASE GLD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22600">
        <property type="entry name" value="MTPAP-like_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03828">
        <property type="entry name" value="PAP_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81631">
        <property type="entry name" value="PAP/OAS1 substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Poly(A) RNA polymerase mitochondrial-like central palm" evidence="12">
        <location>
            <begin position="267"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="domain" description="PAP-associated" evidence="11">
        <location>
            <begin position="496"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="115"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="614"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="685"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="121"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="629"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="640"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="720"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="751"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="811"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="837"/>
            <end position="846"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF22600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0023570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="846" mass="94060" checksum="AAC9BD95CABFC9F1" modified="2023-09-13" version="1">MEIGTVTMTSPVEPGIKKSFPDLVYDTILIEKATNCRSELSVQATRTYASITLKELSDAFRIAQAVCRDYHAENESHLQSAAMEAELAQAGLSNEINLMKYIDTIGYGSNGTVSHRHDIQQSHPTPSARQGSETGIMLPIPDAESMRRFQEQYGKAPAIQHDMMARIVFRLRQELWNQTVQPNHRDRAVANAIYQYGSRYCQQRGFNKPQPVVLSGLDRSKDHIARIEAHLIGLKIIDGVLHKKTYCLQGELQLPVVEPTSVAIENISASMMSLYQRLVPSTQCILARTQLMQKLQRILDAAYPRDNLRLKEFGSCASGLGSESSDADLCITTTTFQRTKPYNDMRSLASVLRRGGMINVQPIISARVPIVKFDDPTSRIKCDINTNHCLGIHNSELIRCYTMIDDRVRPLLYNLKALVKKHHINDSSQSWLSSYAYEPPILPSLQAQPKEFMTSLHITEMIEGRSGGGGGSMSFDCTFDRDYTRHRNFGAANKKSVGQLLIEFFEYYSRYFDYQTMEVNVRLGGGVRIRDEITLKLAKGGAKRAPQPGRGEKKLIIKDPFILDRNVSGTCIGRKLEKVWRIFEHIYLTLSKGEFEKAFEPIPEYYFRDLEEQYSEPAPRRSRMKKAERKLERKTETQRQSRPATALAPSTRTATQPKVSSVNGKAKALPETTVTTAATPLTVLSADKTSNDSEDADSASKRRRARRATAREFHNGLTQGSGADGASGASSSNVPNNSLKPKSEKKAVAKSQLNQSISQSTLQGSTTVTHASPSKTSSLHSKNQKKQLKQAFPVLEKTRKLLLQSKKPDPGVSGAAAASTTVSSNQESSSVRPKQVPTANPTVKQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N6R3</accession>
    <name>A0A9P6N6R3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Mannose-P-dolichol utilization defect 1 protein homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_008891</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Membrane</location>
            <topology evidence="1 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the MPDU1 (TC 2.A.43.3) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000005">
        <property type="protein sequence ID" value="KAG0024733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N6R3"/>
    <dbReference type="OrthoDB" id="271506at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1280.290:FF:000006">
        <property type="entry name" value="mannose-P-dolichol utilization defect 1 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.290">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016817">
        <property type="entry name" value="MannP-dilichol_defect-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006603">
        <property type="entry name" value="PQ-loop_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12226">
        <property type="entry name" value="MANNOSE-P-DOLICHOL UTILIZATION DEFECT 1 LEC35 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12226:SF2">
        <property type="entry name" value="MANNOSE-P-DOLICHOL UTILIZATION DEFECT 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04193">
        <property type="entry name" value="PQ-loop"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF023381">
        <property type="entry name" value="MannP-dilichol_defect-1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00679">
        <property type="entry name" value="CTNS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 8 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="125"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="154"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="196"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="222"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="253"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR023381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0024733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="277" mass="30002" checksum="C88B579AC9394DA6" modified="2023-09-13" version="1">MQLPFFLKTPAVAIIGETCYSSLIEDFNYHDVPCIKYAISKGLGFGIVAGGAIVKVPQIIKIVKARSAQGVSLSSYLLETLACVIGLSYNFRKGYSLSTYGETFFVTIQNLIILGLILHYSGKNTSAFVILSSFLFFGSLLVRTTEFMAVDGTVVTTAFVSQGVLAVLQATTIPINLISKVPQIVENHKNKSTGQLSAFTVFNYFAGSLARVYTTLTEVDDVIILSGFLLSTLFNCVLALQMALYWNNSVAKPAKEGKTEGPASVSSETKKRAKKLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SRL9</accession>
    <name>A0A9P6SRL9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008365</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004501">
        <property type="protein sequence ID" value="KAF9992910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SRL9"/>
    <dbReference type="OrthoDB" id="2110130at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019887">
        <property type="term" value="F:protein kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034198">
        <property type="term" value="P:cellular response to amino acid starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23346:SF7">
        <property type="entry name" value="STALLED RIBOSOME SENSOR GCN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23346">
        <property type="entry name" value="TRANSLATIONAL ACTIVATOR GCN1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24987">
        <property type="entry name" value="HEAT_EF3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9992910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="195" mass="20615" checksum="246934C9119CDFAA" modified="2023-09-13" version="1" fragment="single">MPSVEMQNGTSTAEVNELVEMLSQLYTAPTSEECDAIARNMAAKVKQEGLISLKTNNILANLEAEAKNKKSGLAREGALIGICALADVLGRPSEPFMFPLLPLILDLYADKGPVVQDAASRAALAIVANMPSQSAAILLPILFHSIGGPGKKWQTKVGALQLLADLSLSSPIQVGIALPEIIPIVKDCLSDTKQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SRN5</accession>
    <name>A0A9P6SRN5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Endonuclease exonuclease phosphatase family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_007763</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004026">
        <property type="protein sequence ID" value="KAF9994619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SRN5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09083">
        <property type="entry name" value="EEP-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9994619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="296" mass="33861" checksum="2DF62B183923D956" modified="2023-09-13" version="1">MQDNNKNNTDNRPNQLLIRLYTHNIRYATAYPFKNELPWSKRAPLIIRSILFHSLHNPESLICLQEVLHNQLLDILEGLGPEWSHIGVGRDDGKKAGEYSPILFRCCIWAVQSSQTIWLSPTPDKPSKGWDASNKRILTSALLRHWKTGQSVLALNTHLDDQGTRSRLESANIILAHIAAQQEQYRKNEQQQQQQQQEQFTPDEETYLLLATEDSPLLDLRTTVGKSDRYGHKNTFTGFESRPVDQKRIDFLFLSKGCWDVQGYGVLETKFEDGVYSSDHRPVVGDVSLSLKLPPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SRX1</accession>
    <name>A0A9P6SRX1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_007749</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004013">
        <property type="protein sequence ID" value="KAF9994677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SRX1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9994677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="87" mass="9973" checksum="B060BA039E693B2B" modified="2023-09-13" version="1" fragment="single">ITQGNATIKIAWIRIATSIAKTIQTVNSLVSKEYFCQTFHELFLFRDFVDDDLTDMARLADEKWTSLDLQSYGFHSLEKTNNNAPIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SSY0</accession>
    <name>A0A9P6SSY0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_006636</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010003285">
        <property type="protein sequence ID" value="KAF9999118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SSY0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009927">
        <property type="term" value="F:histidine phosphotransfer kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16922">
        <property type="entry name" value="HATPase_EvgS-ArcB-TorS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43047:SF72">
        <property type="entry name" value="OSMOSENSING HISTIDINE PROTEIN KINASE SLN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43047">
        <property type="entry name" value="TWO-COMPONENT HISTIDINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="Homodimeric domain of signal transducing histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="1"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="550"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="585"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="670"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="710"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="595"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="611"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="722"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="784"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9999118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="784" mass="85718" checksum="3D90AA77ADD39351" modified="2023-09-13" version="1" fragment="single">PFSGILGMLSLLRDSSGLSSEQFEFVDMAKASCEMLIRIVDDLLNFSKLEADKVTLEYIPLCFEEIIGDVCDLLVPLASRKGLELIILFDMTMPLLLIGDPDRIKQILMNLIGNAIKFSTSGNVVIECRHEVRKRKDIIRARKEKFSQDALRTLASGKIPATEGSDIEIDDSKLGDEVTLYCAVKDQGIGMSPEEQKMLFVSFQQTDNGTTRKYGGTGLGLSICAQLIEHMHGKITVDSKKGEGSTFTFSAKLRTETAYDEEQNPAESFRIRECIRILAARLDMILGKKVLVLSPNKQLRQQVVLSLHGAICTEFDSMEAALASGVILMTADSTTDPVDGMDVDGDDINPQDGDASAHDGAFNRESMTQFDFIVVDHVLDSEEIDRIYPSPLIGFVLLLAPTTETLRWILPPATKLNQEPEEYESGQVDIGGRGRVPITKEAVEAAEKLATGRVQRTSERDGASDNCISRNTRKVPSQLFKKRKSRGYITVTRPVPRVIRKHYDGDKGALETSTFLVCRLIKPVRRMKILQIFYNAVNMYNNGGQMPASGWESGSSTYDWQSDHDRRSNISGYDEDELADRQPHVLASEPSSPTSPSLFVPMSSQSSPSSSPCPQPMLPLPPCLSPSVSSLKRRRDHAMQNTPHANHDTCSCNGSNCKCSGCVDLKRRSKATRRSSAGASVATLGSDHTSTAASIASPSLHPISPLSISLDSTVESDPPRNLGLSGAAMGSGSSCSQDSNANMPKRARNNDALTLLLTAKELDSCRGKNVLVAEDDFVSQKILE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ST54</accession>
    <name>A0A9P6ST54_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_006610</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003270">
        <property type="protein sequence ID" value="KAF9999249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ST54"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9999249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="160" mass="17275" checksum="EAFC39C0CF3A9DAC" modified="2023-09-13" version="1" fragment="single">GDIRKVPIEDTDLGFPALQVSDGNGGYKDIPANTVFDLTTVNATVPIVLSRLGSHTPDFTIRVFDSNKKNFIGYLVSNDQGSAVGYRGRDADVDETTGELVFEPYTWQGGVIASENSTTTVTVPSGTYDIVVASQKKFTKGHYPSDYEVFDLGKVTVKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SU50</accession>
    <name>A0A9P6SU50_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNase III domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005899</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002902">
        <property type="protein sequence ID" value="KAG0002893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SU50"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004525">
        <property type="term" value="F:ribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00593">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1520.10">
        <property type="entry name" value="Ribonuclease III domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000999">
        <property type="entry name" value="RNase_III_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036389">
        <property type="entry name" value="RNase_III_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00636">
        <property type="entry name" value="Ribonuclease_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69065">
        <property type="entry name" value="RNase III domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50142">
        <property type="entry name" value="RNASE_3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase III" evidence="1">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0002893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="168" mass="18831" checksum="4A761AACE247AC9A" modified="2023-09-13" version="1" fragment="single">ASNQRLELLADAVLKLTAALYYYQKYPDTPANNFRTFKGSILSNDALGSLFASLGLDTFLNTGLADSVNSEAKLKKDARRAVYLRNLGITGWANLDFSRRLYPLVDRSNFKSSIGEKRKFVEVDDEEITSGHAANSRYGSLCTMLLIMVCGQDIMPMVPDYAEHRHHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SVB6</accession>
    <name>A0A9P6SVB6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Eukaryotic translation initiation factor 3 subunit K</fullName>
            <shortName evidence="4">eIF3k</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">eIF-3 p25</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_005152</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the eIF-3 subunit K family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002559">
        <property type="protein sequence ID" value="KAG0006743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SVB6"/>
    <dbReference type="OrthoDB" id="337745at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005852">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006446">
        <property type="term" value="P:regulation of translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.250:FF:000001">
        <property type="entry name" value="Eukaryotic translation initiation factor 3 subunit K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.250">
        <property type="entry name" value="ARM repeat, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03010">
        <property type="entry name" value="eIF3k"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033464">
        <property type="entry name" value="CSN8_PSD8_EIF3K"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009374">
        <property type="entry name" value="eIF3k"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016020">
        <property type="entry name" value="Transl_init_fac_sub12_N_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13022">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13022:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10075">
        <property type="entry name" value="CSN8_PSD8_EIF3K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="5">
        <location>
            <begin position="46"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0006743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="226" mass="25461" checksum="FB7889C05A5682FB" modified="2023-09-13" version="1">MARVSNTPSSRPEVIQSLIDGVDRYNPDNVSILEEYLATQCTNKECDTMANLAILKLYQFNTHLINDQVVNNILVKALTTLPEPDFNLCLYLLNEQMVTEEPVVRLIALQDLLEQARYADFWKAYEGDDIYKELTAEVLGFEDSIRTNIANAVAMTFQSIELESLQKYVHLKGQALSDFVKAQGWTEANGVVSIPVNKDNEAKTTVLTENIKFEQLTKIIGHSNDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SVZ9</accession>
    <name>A0A9P6SVZ9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Aminotransferase class V domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_004515</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002297">
        <property type="protein sequence ID" value="KAG0007556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SVZ9"/>
    <dbReference type="OrthoDB" id="420046at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43686:SF1">
        <property type="entry name" value="AMINOTRAN_5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43686">
        <property type="entry name" value="SULFURTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotransferase class V" evidence="2">
        <location>
            <begin position="85"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="470"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0007556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="678" mass="75560" checksum="5A7827BF3C23593E" modified="2023-09-13" version="1">MSVKIARETIRRCTNATNTPGHEHQAAVIFSGDGSTSAVNKVRNVFRLGDEAYWTRKSIADTQASKSHLDVLESQLILHQHRPLKLGTFSAGSNLTGVLNDTVAISELLHKYNAFAFFDYAGVGPYTTIDMNPAPSSNQIRNLAYKDGVFISTHKFLGGPGASGVLVARFEIFDWTEKHSGTNRNDYVPAAPGGGTVDMVIQGKHKYTNNVLAREEAGTPNILATIRTGLVFRLQEIMDPAWILQKEYKLARNILGRLTAPGMEKSIHILGASERDRVAVFSLTIAVPRMLSRDKERPLQIHYTLLSTLMNDFFGIEMRGGCMCAGPYASQLLKFDADKEAAFWRLLMGYDKDPNSDNNRPCTNIHQMDLHSKSLKPGFVRFSFSYFAKDKDVEFVVQSLEWMAQFGYLLIPLYKLDARTGEWTIREAVRKAVLSGIPSKRMTTGQRKHCIPVAIHCIYGLQKLFQEQSKSRRQQSIPPISQPLDLNLKGYPDSGQENSRSQIFFAPHQAPRDPSNTAPRRPENSESSIALHNDLEHDNLLRVPNMLHNVSSSDVSSIISSTSEYTVDLNQRRMGSTAISLPSSPSATTIHTPNSTSNILKKSGLFLTSFLTSPKDQRLLDDALKELSMDSLRAEINAVECSELAKELRWFVSPLDVALLYTQELANPSQTSPFPHMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWK3</accession>
    <name>A0A9P6SWK3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NDT80 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_004058</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002112">
        <property type="protein sequence ID" value="KAG0007934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWK3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000228">
        <property type="term" value="C:nuclear chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1390">
        <property type="entry name" value="NDT80 DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052605">
        <property type="entry name" value="Fungal_trans_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024061">
        <property type="entry name" value="NDT80_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037141">
        <property type="entry name" value="NDT80_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008967">
        <property type="entry name" value="p53-like_TF_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35144">
        <property type="entry name" value="MEIOSIS-SPECIFIC TRANSCRIPTION FACTOR NDT80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35144:SF2">
        <property type="entry name" value="MEIOSIS-SPECIFIC TRANSCRIPTION FACTOR NDT80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05224">
        <property type="entry name" value="NDT80_PhoG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49417">
        <property type="entry name" value="p53-like transcription factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51517">
        <property type="entry name" value="NDT80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NDT80" evidence="4">
        <location>
            <begin position="11"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="NDT80" evidence="2">
        <location>
            <begin position="11"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="239"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="299"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="255"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="394"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0007934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="521" mass="56786" checksum="A0D9B7B63991B11C" modified="2023-09-13" version="1">MSIGPDGLPVSGYSTAAPSPTSTQSMLANRSKRRSEVFASHESPQFYPVPQNYNVLSIDQSTRYNFRITAKIDRGFFLAANDWTCYRRNYFQISASFNIQGLDPAIHSEVPCLVDRNGELVKINKFLICIGAQIQNGEKAIELVQHTPKRDKGPQITPKPTPVRAGGDLNLYSAGSNPNVVTFERVQFKTATANNGKRRAAQQYYQVHVDLFGESDMGELILVASSISAPLVVRGRSPGHYADNDDGAPALSTRPMDDGYYRHDSISSNGGGPLSVNGDYQYYSGYGYGPSYQYQSLGSASHMAAQPQDPNNGYYERHDQESYPTSPLSPGARHPGPLEASQPHHGGHPYMTPQIHHGFSPASNSPDVYSPPNFIGSGAESPTSFNRIPQDGHYYSSPSYPQYPSQQQQEQYEQYQEEQEAQMAGLRIHSPKSPGSPIMGASARRQSFSSALSKKGNERGVVGLGLGGVGPTRKSRSISMSAGITKRAPSKTRSSRTVPVTPTKELTKGLGISSDRIPEEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWQ7</accession>
    <name>A0A9P6SWQ7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Sel1 repeat family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003042</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001783">
        <property type="protein sequence ID" value="KAG0008800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWQ7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0008800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="80" mass="8812" checksum="AEDF3FBFE5D97B84" modified="2023-09-13" version="1">MYQLGIGVPQDNTEALGWFQKSALQGDANAQYSAGPMFLNGKGTSKDVTKALEWWSKAATQGRMEAKHKLNEHKTTCIIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SX29</accession>
    <name>A0A9P6SX29_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_002512</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001621">
        <property type="protein sequence ID" value="KAG0009317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SX29"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0009317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="149" mass="16939" checksum="28549BF5B1A83EA1" modified="2023-09-13" version="1">MCSSDGPSESILASVMAVIKDRKYRDYFKQPKESDFIDEEEVDDDGDLGPDYVAPHRESHWKVLKPLLSCNVETLGECSSMESKETEEEETEEEEIVFVVGNISAVEVIEEGDEDDECEGEGVQDSYKSEDVEEYYDDDDESEEENINL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SX37</accession>
    <name>A0A9P6SX37_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Inositol polyphosphate 5-phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">INPP5E</name>
        <name evidence="3" type="ORF">BGZ80_003196</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001832">
        <property type="protein sequence ID" value="KAG0008663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SX37"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004439">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046856">
        <property type="term" value="P:phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046985">
        <property type="entry name" value="IP5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000300">
        <property type="entry name" value="IPPc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11200">
        <property type="entry name" value="INOSITOL 5-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11200:SF275">
        <property type="entry name" value="LD06095P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22669">
        <property type="entry name" value="Exo_endo_phos2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00128">
        <property type="entry name" value="IPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Inositol polyphosphate-related phosphatase" evidence="2">
        <location>
            <begin position="287"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="246"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="461"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="677"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="844"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="986"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="89"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="275"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="488"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="505"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="677"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="737"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="754"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="879"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1024"/>
            <end position="1035"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1038"/>
            <end position="1047"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1061"/>
            <end position="1075"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0008663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1084" mass="119069" checksum="6E0847E4D264B38D" modified="2023-09-13" version="1" fragment="single">MEAWVSPVSNWLFGHQKTKPVTAVSDQPAIEHQSRPLSEEEEETKEIVPQQDVIGNGSLLINNTSITDTTTESINPVEPSHQRETTEESLQQTLAQASQASPTQEEGAPKLLEKLRAVTRAIGWLLSNSTEGQQNSDTNTDAKGRDQDTGPSTKGIGNRRKKKGHKKPLPPPPPPKPVISKKRLKVFVGTWNMMGQMPRARDGLTGFIDVHDPAHPVPATKNPVDQGQQAHNASHLHLKHRSHIPNPAEESLLNSNSDIYSSMEGPGLSQHISRTPRDRNQVGNDHKQQQTHGLKPSVLEDPFLEMNAGAPYHIIVINTQECEREIREAVLFPSKVAWEKQLQASIGPEYVMIKTETMAALHIAVFVWKPIESLVNAVDSSTVATGIAGIVGNKGAVAVSVYLGSTSFLFVNAHLTAHQANTHARNSDYKRIINELQLNDTPKNSPGLWYFKGDMKLRRHYNSPPPLVPQKSFKIGANGKVNGEKPNGKSNSSGNLTRSPSKAKLVPESKAPDHSHGSSDGHSNGQAQVGTAVDITEQFDYTFLAGDLNYRVDLTRAQADDYLQKGDLETLFAHDQLTAERKAGRVFEGFMEAPIRFKPTYKFDPITPISDNRLKNRQKTLLRHKSLVNLSDNFHMHHGSISRLEHNLSTPTLNVGASKCDSGSSLSLSAEANVFTKSENVNSGERTNGNSGNNEAGKDGSKVALSNRMNESGNHIKEPTRKLPVSKEPSSIPRPPNSESYLNHQSDNAPAQASHEKDNSKRSDGTKVDLPENGERQLEKLRQVQLERYDTSGKHRVPSWTDRILWKSTGGNHYLPLEIGDDTRSGGGDHGKGGWSLLRKNRTKIASSSSQSQTSHSEETLGRSPEQYQRVQDMRAESTSESTTVLGSESGSMSILKLGRKKNKEGSRDGKMSLLESLKLYRPGHKSRRDSTPPTPQSSGMSEEDEDRAAVIVKQYTAHHDIGQFSDHRPVTAVFAVRFDWNLTDRGAIGDGAETETRVPGKKRSFPDAPEPARRSDISSRLGNLSNTDTSSLSTRATNRDGSRADLDVEETESTLESTEIKFSTIPTSSLTTGGANDRHEEGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXN3</accession>
    <name>A0A9P6SXN3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DNA-directed RNA polymerase II subunit RPB3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">RPB3</name>
        <name evidence="8" type="ORF">BGZ80_001553</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001358">
        <property type="protein sequence ID" value="KAG0010355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXN3"/>
    <dbReference type="OrthoDB" id="270173at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07031">
        <property type="entry name" value="RNAP_II_RPB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.120.12:FF:000002">
        <property type="entry name" value="DNA-directed RNA polymerase II subunit RPB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.120.12">
        <property type="entry name" value="DNA-directed RNA polymerase, insert domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.10">
        <property type="entry name" value="RNA polymerase, RBP11-like subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00320">
        <property type="entry name" value="RNApol_arch_Rpo3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001514">
        <property type="entry name" value="DNA-dir_RNA_pol_30-40kDasu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011262">
        <property type="entry name" value="DNA-dir_RNA_pol_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011263">
        <property type="entry name" value="DNA-dir_RNA_pol_RpoA/D/Rpb3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036603">
        <property type="entry name" value="RBP11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022842">
        <property type="entry name" value="RNAP_Rpo3/Rpb3/RPAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036643">
        <property type="entry name" value="RNApol_insert_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050518">
        <property type="entry name" value="Rpo3/RPB3_RNA_Pol_subunit"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001988">
        <property type="entry name" value="PRK00783.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11800">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11800:SF2">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01000">
        <property type="entry name" value="RNA_pol_A_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01193">
        <property type="entry name" value="RNA_pol_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00662">
        <property type="entry name" value="RPOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56553">
        <property type="entry name" value="Insert subdomain of RNA polymerase alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55257">
        <property type="entry name" value="RBP11-like subunits of RNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00446">
        <property type="entry name" value="RNA_POL_D_30KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="DNA-directed RNA polymerase RpoA/D/Rpb3-type" evidence="7">
        <location>
            <begin position="19"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00072506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0010355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="281" mass="32084" checksum="FA6EFEAEBFA8402A" modified="2023-09-13" version="1">MDIYNGGPEVSIRSIKKDSMKFVLSNTDLSVANALRRIMIAEVPTMAIDMVEIETNSTVLTDEYIAHRLGMIPLTSYDVDRIQYTRDCTCTLYCPNCSVELTLHVKVNVDYDDMNDPTIDKTRQVTSLDLISSDESVKPVSDDKAHPILIVKMRPGQEIKLKCVAKKGVAKEHAKWSPVYGVAFEYDPYNKLRHSHYWIEEDEKLEWGVSANAVEETPVDPNEPFDFNAKPDRFYIELETSGCMKPEEVALRAMTIMQDKLGGLQIKLDDEFKEDTQRWGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXP8</accession>
    <name>A0A9P6SXP8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Galactose oxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_001501</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001341">
        <property type="protein sequence ID" value="KAG0010424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXP8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093:SF18">
        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="414"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="384"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="443"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="387"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="454"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="686"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0010424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="686" mass="73421" checksum="9650C800A0B391EB" modified="2023-09-13" version="1" fragment="single">SVATNLATLTGFMAVYGLFGGGFISIFPVVAAQVVGVERLSSALGIIYFGNVFESFKPNITAFSSNVFIDSSALYIQGGATGFNPVTGVYTTIPQSFAIDLTVSWNINQPAFKSLPDGPTGSLMTAALAPGNQSFFIFSTGISHTFDIKSSTWNGTLSNNQLTQNPGLGSATDPDSGSIFIPSIVGGSVSGVTSLLTMHVTGASFDNIIGQSFPDVATGFIVAWSTALRSMLVFGGSTTFAAAPKQNDNVIFYTPASGTWGTLNLNTSQVIPTQRTGSCFVPILGGSKMIVFGGLSNPVALPLVAYSDLYILDTSSRTWSAGASAPATEGRQGAACAVSNGQLIVWGGWDITYNTKNTTLVYNINANTWVSNYTAPLIPTTLPPTPTATSISSSTHSPSGGPNPNTPSSNSPNVPAVAGGSVGGLTVVVMVVLFVYRARRKRDSAGTGFDEKQGSLPPTTPSPGNSSNDSLDPKNDPSDSFYYPPPPSSKESRSPYYPPPPKSNDTYWADAYDQYKVRRNPEAVRFKNFYSSANHQEDSRVPDMVLQHIPISKRGNVHEGTFGSQRFSQHPHTGTEGMMEPESYHDRSLRSPQTADEGSPWQYHDSFDYRKQVQHPHVIVETTEPTATRTRTHNQDPHVVVKTAVPMTARTEAHNINYQNQVQHPHIIVETMGPTTDNILDAYIIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXW2</accession>
    <name>A0A9P6SXW2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Bud emergence protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">BEM1_1</name>
        <name evidence="8" type="ORF">BGZ80_001555</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001358">
        <property type="protein sequence ID" value="KAG0010357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXW2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05992">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06890">
        <property type="entry name" value="PX_Bem1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11878">
        <property type="entry name" value="SH3_Bem1p_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11879">
        <property type="entry name" value="SH3_Bem1p_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035550">
        <property type="entry name" value="Bem1/Scd2_PX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035548">
        <property type="entry name" value="Bem1/Scd2_SH3_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035549">
        <property type="entry name" value="Bem1/Scd2_SH3_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051228">
        <property type="entry name" value="NADPH_Oxidase/PX-Domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053793">
        <property type="entry name" value="PB1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000270">
        <property type="entry name" value="PB1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15706:SF2">
        <property type="entry name" value="SH3 AND PX DOMAIN-CONTAINING PROTEIN 2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15706">
        <property type="entry name" value="SH3 MULTIPLE DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00564">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00666">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54277">
        <property type="entry name" value="CAD &amp; PB1 domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51745">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="5">
        <location>
            <begin position="30"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="5">
        <location>
            <begin position="190"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="PX" evidence="6">
        <location>
            <begin position="400"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="domain" description="PB1" evidence="7">
        <location>
            <begin position="592"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="92"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="292"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="520"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="96"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="131"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="168"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="303"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="335"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="347"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="537"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="565"/>
            <end position="579"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0010357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="666" mass="74721" checksum="0AA6D2283139A823" modified="2023-09-13" version="1">MTNLRRSLQNKNNAGGLSPTRNHATAALEPPLKVIKALYDFNTQQPEEMSFAKGDFFHVIGNEDDEDWYEAYNPVSGARGYVPVAYFQVLEKTRQKQPQQPQQQRGQRNSSQSLEDTGNDSGTFMDPLPNQYYSQHSPQQQHHHPQQYPQHGHAHSTSGHLPQGGGMISSSISSPAMSQKSAASSTTTKYQPLYGIVLYDFSAERQDELDCKSGDAILVIAQSNEDWYVAKPIGRLGGPGLIPVNFIEIRDMASGKPINVPEMLRQTGMVIPRVDEWKRQELEYKANSIPLGRFDAGMNRGPQQQQQQQQQQQQQQLYQQQQQQQPSQISQQQSALPKNNTQNFRDQGARKNHSQDLDISRRMEGSNGRASASRSYSHDIYEDQIDSRYHHNRSFSNSSNSASRIVHATVESFHHEDDQYWYSVRVELASGATRSLFRLYEDFYNFHIALLEEFPVESGRVGDQPRILPFMPIPVAVVTDTVSASRRADLDGYVQDLCRLPTRITQHPLVEQLFAVRDGDSETPAESGVTGAARSISPVQGRNTSYRDQASPTLGAVGTGGQRATALSPTLRTQSQFPQPTLPTPAGTPSDMIKVKISYQEDIMAMRIPVAISFKALQQKIFDRLQTENRNLSYRDDRGDFAIVQTDADVRDAIDQSGGKLMIYVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SY89</accession>
    <name>A0A9P6SY89_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_000756</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001165">
        <property type="protein sequence ID" value="KAG0011339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SY89"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="598"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="819"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="876"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1125"/>
            <end position="1148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="604"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="631"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="895"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0011339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1239" mass="140313" checksum="ADE0AFAD77AC96C9" modified="2023-09-13" version="1" fragment="single">QGQDDQAWRDFLRPEQRQTIDWYEIAPAERYHSRNYDPHQGVPIAENWRLSPMNPITQASVLASRASSIASDSIGGSHAPGPAAGAGPPLEDWNAGILAYGHSHHQLMERSRALKAQYDEWWAMEENLNNSVDNFQRLVRQIYGLDGVLETMRESSLSMSHLFSLVENAQAMPSSGFVEEETTQQMEARLLGSNNYVIRQVAASQAEIVRFANEEKLKIRSLRLQLGLLDVMDEMSNAFSMQNLNNQNQGPYAGFDLFAVLKAPGRANELSEMYHRPELATLEAEVHEKCAIVKTNEKELERRLYLHNMALDLATPKNGAQVKRLMSIESPIALQMFNTPSVCQVERLEIDLRRVDWVDELWRIRSSQNVMPRSLRHSLEMYQEANNSNHEVMNSERCLEIGYEIIARNWRSLEQVTWIGPSCRGCFIGEIDHECDNSKPCTLDVEPILQRVQEQEHAGQDRQQLRESISGNLSQDGIPVPPPMPSLEQSRLVVLNLQTWRFTRTCLNSILESCSHLLSLELKQCVLMSGPDARSEEIVLHSSSSTVNSNNSQRRDVAPVFQHRGLRSLAISMSTLFTQQRQHSFYSILQGREKVSHNDEYLNGSDSETEASTGFSPSNGQEGPIPDGASDHSSSTSSYESIEHRPRTVTRSQSEAIDLLESSLFEHFPNLEHWKLTPGLENFRMVTWIGREIQRHCPNLNKLTIAPNAFVDSECTALLVRAFRPMPDYRLSTGINSAIVSIPLAEENDSDNIFLRGGYRLANGKGLKVFRAEEDLYGRALVKALMLHTSTLEVLDLDSSNEYWNLWPGEVDGEFVRTPRSHTTLRRTGSVERLPQGPPLNIFQDAPIHHSHNETLEPPPRASQVALVNGQGIGLGYGNQLPQNSSAGIGPDQGQTPQSFSAPSPTPSTQSSDESTTSTYNEDDDEDAYQGPWVLRRPYAHLDALLQQCARLRQVKLPRNEIDVMQPHMAYPWRSSSTLEELWISIHGLYCTTEIAQILNDIRAVPVRSFERLRDRYDNPEGIIPLAPREFNANGLANSFNSRSQFQEYMDRNLYHEDRYVPDYEAPVTDNENDVQEPNARVSIPPTPGTLRYQVIQLLRQFTRLRYIWIGEGLYMLPPRAQGEQRQRLSNAPGGQGPTVIPDGYPTRKGSVDMSDMAFRNRLLKRIEIPLFKYSAKNHGRSKISLSSASASEEYNSARVYDILGDVPRSVGRMGLKRKQSENELEQDLNNRNIRFKYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYT8</accession>
    <name>A0A9P6SYT8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_011692</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000972">
        <property type="protein sequence ID" value="KAG0012511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYT8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18870">
        <property type="entry name" value="PROTEIN TAG-278-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18870:SF9">
        <property type="entry name" value="PROTEIN TAG-278-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69989">
        <property type="entry name" value="C-terminal domain of PLC-beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="26"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="922"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="369"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="499"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="606"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="716"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="873"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="964"/>
            <end position="1044"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="26"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="106"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="241"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="922"/>
            <end position="936"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0012511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1049" mass="114762" checksum="488622AEC5DA46BA" modified="2023-09-13" version="1">MAVTQDAPAPSASAARRAATAATVAANKAKAASANKTQTSSTVATKTAASTNSPTSKTAATATAKPAPKPSTSSTKTAVSKTTPKAPTTTTTIKTATSGPSATVRKSATPSPATKPTTGTRPSTATKSPSTPKTPVAPKTPSNATKKPTTSSSATGTASSSASPAAASRRVPATATARTTTSIRVPPATTGSAAKPPAVGGRPPVSMTATTIRLPPKTPATKTPVKKDAASAPGTPISKPVSKTGTAASSHNRASSMATTTVKKMSTAGTASPAGSVRSVRTTASVPASPMELKKAIASVKAKFEDVSTRLKVKENELVSLCTQLDVALSFDNLAATETASSDGGETLVPEIDLSKLASKDKDVVMAVISAKEKDITRKKNQVKTMKARVEQLRMSNERTLKELKQKDAELQEAQDQELASLHVELAESIQKHNDVVLLRQKLEESRALHSATIEKLNRIHDNKLQCLEVELQSIKRGRLERSGEGYFNDLEPIREAHRKELTHLLGEYRKEIEEFKAQSDAQEKQEVDEFQTELKERLDSELKQIRASHASLINERSSAESNMANVLQERHVRNLEDMKIKTEKDHKTYLGTVHSKHQSEIERLKSKHDARIAELESKIETLQEKYKADLADIRSKADATSNELVSKHSSEIAACKEKHAADLINIESSTKEKMQLEFDAVQAKFSSFVGNIQGTQDSAMRDLEAGYETRIAELIVGHEDRVRELENEANEQVEQELERVEMEFERDQERIIEEHAQKLEELRASHQVIITKLEDQLTIAEGRAKETIEATRQRKRAHEEEMNEVKAELEAQLSAVHTSTEALINSNERDGKSRAEALQAGHAAIIGTEKSAFELKLSEALTKKETAWNNRNELQIREIKSIRSRLSDAKAECDKARSAVSAIETRMKEEYTTSVNRLLKEQRSRLDHSQDESRTRLAKVTRTHDEHAEMHENKLADLQTSHHKQLQALRDQQEAVLKSREQENQRRIVALQQSLAAKMASSGYGSTTSLRAAQELSELKKKAETLQGENEQLERVVKHLQQMMPTIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYV3</accession>
    <name>A0A9P6SYV3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_011638</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000961">
        <property type="protein sequence ID" value="KAG0012596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYV3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="79"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="30"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="263"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0012596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="326" mass="34058" checksum="867009B848163915" modified="2023-09-13" version="1">METINGTQVPISSSSATSISSSTTVLSTTTTTTTISTTSQTTTGSASTATSSSTSGDIVSTSPTTVPESASKTSTISPLVIGLISAGSVALVVAIIAIALLLRTRRRFKDDSGDFTSLRDNPSSPTDETSKSSIFKSEESQDILSRGAAVGAPFGAMAAGRSSSNTVRSAEPMIKEAPNMLAYNSTQSPPSPTASLPLVERGSPILGRTPESSEGVGSGAETTDGVGSEKSSRGTKGSALTAGDAQLIAETFRKSMRRPRWDDTDDQDEEEQDEARRAANELLKRELSEQGLDVQRGVQRRVTIQDSTHRSSAHPPLSHKTDDSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZG0</accession>
    <name>A0A9P6SZG0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Arrestin C-terminal-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_010822</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000799">
        <property type="protein sequence ID" value="KAG0013813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZG0"/>
    <dbReference type="OrthoDB" id="2333384at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031625">
        <property type="term" value="F:ubiquitin protein ligase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070086">
        <property type="term" value="P:ubiquitin-dependent endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011021">
        <property type="entry name" value="Arrestin-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011022">
        <property type="entry name" value="Arrestin_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050357">
        <property type="entry name" value="Arrestin_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188">
        <property type="entry name" value="ARRESTIN DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188:SF17">
        <property type="entry name" value="FI21816P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02752">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00339">
        <property type="entry name" value="Arrestin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01017">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin C-terminal-like" evidence="2">
        <location>
            <begin position="181"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0013813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="340" mass="38022" checksum="00A452B71469CD8F" modified="2023-09-13" version="1">MTQKQENSKELKLSIPTPGKGPGDVPLVIGAHDTPGAIKGAVSFECNYDCKGSNIIIKYTALAEVRWSTKSGNKTIHYRGRHLYDKKIVQMTLQHTQEGKVSAGKYLCPFYFSIDAMYMPSSFVGTYAWMTYKVRATLVRKFPSVNLVREQVVWVLNSALPRPERPLIDTPTQMTRYKGVLMKTVPYICIIPSNVIYLGQQVPITIKILPAESPVQVMSGVIKLKQYTTLNVRGGEKSNKKELLNVTLKDGWPQAEARNSWQRTIVVPIPGFPQVTPSISSPMITKSHILKLILNAKIGKNGHRSELRVEMPVTITGPRPAGEPYPSFDLHRYLACVDKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZM4</accession>
    <name>A0A9P6SZM4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">SLC26A/SulP transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_010752</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000784">
        <property type="protein sequence ID" value="KAG0013948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZM4"/>
    <dbReference type="OrthoDB" id="288203at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001902">
        <property type="entry name" value="SLC26A/SulP_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11814">
        <property type="entry name" value="SULFATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="239"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="315"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="401"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="533"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="599"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="643"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="680"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="707"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="739"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="domain" description="SLC26A/SulP transporter" evidence="7">
        <location>
            <begin position="210"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="domain" description="SLC26A/SulP transporter" evidence="7">
        <location>
            <begin position="532"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="781"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="60"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="73"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="830"/>
            <end position="843"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0013948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="901" mass="98540" checksum="A0CCBF3B3ADB72E7" modified="2023-09-13" version="1">MPQGTFQPPLHPTAGSSAGPASDLRINITSDQHIFPSQEVLQSPVSEFPETFPPPPPPQGNTLETPIPNTENSSFVSSCSSSVHDDTSSTLSDSAESSSSLGGLNHVNDGVAGSTVQRKMSRVYSTDDLPQRKFSMDAARRPSATFADLQQLRQQQRPPNRKPSSSSLLGPANDEIISVGKESSYKPWLRKYIPAYGWLISPGYNLTDFPDDLIAGITISTVVIPQSMAYAMLAPLPPVYGLYTSVVPIFFYCIFGTSRHMHTGTFAITTLLLGQAVRSLIAQDKSSSSLVETLLYDTHLPRQPSFEDPEYEKRFIGMILMLSFVVGCVQVIMSFLRVGGWASKHLLPDALVGGFNTAAVFHIGTSQLKHFLGIKGMPSYQGAFALLKSWMWVGDHFLEETNWYTVALGTVAIVFMVIMRKLEQKRKAKHELMLRKKEMLMVQQRQAVSVAIVRNHEAQRQRRWEQQPFAVSPSINADSSNNSLRTVTDGNDATTVRPAVTFAPTVPTNLNDPERAIVMEEPPASTSVQDHDVYIPIPDILLAVIILTIVNVIFSLDTPRSNGGWGINVIGSIPKGLPLVTFPANLITSGPKEWLTLNFFVDTIVPMIQPALLIAVIIYVMSFSIAKQFGKRYGYKVDPNQEMLALGLASMGGSIFSGYACTGSLTRTAILSQSGAKTPLASMFGVLTVTTTLISLTWCFERVPNTVLAAIVLVALQSLVMQITEPFKLWRLGQQKAAIIWSVTFAGVMIISVELGVAIGIVVVILTTIYSWVTNRNNDEDEPLLGSRSQGRRRPSRRMSQASINDACQQQRRRDSRDVGDATESLLDNAAAAAAGSSGQQRGRGSGSNPRLSGALSPVSRGMDWKTRMLRTKWGQKVGSLFGMEQPIFSDPLHVNTDDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-06-18" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZU6</accession>
    <name>A0A9P6SZU6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BGZ80_010315</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000703">
        <property type="protein sequence ID" value="KAG0014671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18596">
        <property type="entry name" value="ABC_6TM_VMR1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18604">
        <property type="entry name" value="ABC_6TM_VMR1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000825">
        <property type="entry name" value="ABC bile acid transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF353">
        <property type="entry name" value="ABC TRANSPORTER ATP-BINDING PROTEIN_PERMEASE VMR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="117"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="151"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="182"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="230"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="294"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="396"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="423"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="506"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="934"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1051"/>
            <end position="1079"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1141"/>
            <end position="1166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1243"/>
            <end position="1261"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="13">
        <location>
            <begin position="298"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="622"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="13">
        <location>
            <begin position="1052"/>
            <end position="1293"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="1330"/>
            <end position="1601"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="347"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="862"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1451"/>
            <end position="1478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="356"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="868"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1463"/>
            <end position="1477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0014671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="16">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1627" mass="179624" checksum="82C1C5BA3D1A5431" modified="2023-09-13" version="1">MGVQLMHVLAAIPLAITIVSGTICALAARSSNIELNPSAQPTAAELTRRKSIFDYTKLPSTDAVDNAAANFQPKAKEIKIRNILLFILSLIPTAFILTSLILVIQSGSSDQKLLESLFGPIVLLAGWALVLVVLLGVITHRIRYMNAIQSLQWFYSTTTAILLVEFWYRIDLILEGDYSADMLIFYGVAATVLALFGIALTMPAELDLAFVHRYGYGYSSAEHVMGTEAYASYLSWLFFSWFNAVIKIGSTKTLNLSDLPELLPQLRARTVWSQFQTMTQRFSYINDPTVPPKVAYLYVVLIFVAQISRSLVQSQMFYMGRKINVSMMALLNAEIYAKTLTRRDMSGLVDKKKKGENKDNDKDKGKGGGEKKDNAPASAGKVVNLMSTDTVRVSGVCNFWHIGVSSPIGIALGTYLLYDLIGWSSLVGMSILIITIPVNKAVRKRYAKGQRELSSARDDRVTLMGELIAGIRMIKFFAWEMSFSEKVLKAREIELGKLVNVYKNTILFQLVWFSSPLLVTLSSFFCYARIQKGEFTPAVAFTAMVLFTRLKAPLNGLPAVYMALTNASVSLARIAEYLDEPNIKDVFVNGQKLTEGSPEIGMQGMTAQWWTTESAKAPNANADEQAQSRTEDADQFILRDINVAFPVGELSIICGPTGSGKTSLLMAMLGEMDILSGVIFLPRRPLDGSRVFDHETGLLKDGVAYVSQQAWLQNASIRDNILFGSKYEEERYNEVIEVCALKRDLEIFEDGDQTEIGEKGITLSGGQKQRVSLARAIYSRSRHVLLDDCLSAVDAHTAEHIHSKCLTGPIMKNRTCVLVTHHVRLCIPTAKHVVLMNNGQISVQGSVQQLREQGLLSLVLEEDEEQNTDSSDNETVNGNDMGSSTSIAKPKLVQRKSTSKDVKITEEPAVPIKDAKKLVQEETREEGRVKWSIYMVYASAAGGIIFWFTLMVAFAVTRMIEVSENLWVREWANSYAPDSLLTKFMFSNIYTAMGFSTSHLASSPIYSDSQGFQNQHGLYDPAQAVTNETLSTMGLGSEYIMGSPEKHSTDYYLFIYALISVGASFAHILQTVIVLYGSLRAARLLYRKLLMSVVRAPLRFFDTTPVGRIMNRFSKDFETVDGSIAGNCSQLLSLIMSVSSIIIVLAYITPLFVVVAAIISVAYLAVGRKYISTSRELKRLHSVSRSPIYSMFGETLAGVATIRAFSEQSRFMSDLLVKIDDSNRPFYFLWIANRWLSVRSDSIGALVALSSGMFILMNPIGIDAGTAGLALTYALEFVALVNFLVREYTEIEMELNAIERITEYTVMAQEPPAVIEGRRPPAAWPTGGSIEVKDLEMKYAPDLETVLRGISFDVAPRQKVGVVGRTGSGKSTLALSLFRFVEPVGGSIHIDGINICDIGLDDLRSRLTIIPQDPMLFTGTIRSNLDPFGDHDDNELWEALRRVHLVGSGQESAAVSDNEGDDSNVISASSSSVAGHSTPMGAGNTTHISFSSLENPVSEGGSNFSQGQRQLLCMARALLRNSKIIVMDEATASVDFATDKAIQSAIQQEFENSTVICIAHRLNTIILYDKVLVLDHGKVLEYDTPANLLDDNNGTKSHFREMCERSGELDVLLEMVRSSENKKRSTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T046</accession>
    <name>A0A9P6T046_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_010750</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000784">
        <property type="protein sequence ID" value="KAG0013946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T046"/>
    <dbReference type="OrthoDB" id="2447261at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0013946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="415" mass="46724" checksum="AC0D43537E709FAF" modified="2023-09-13" version="1">MESQENLQSTQVDAMQSNLLSIPYQLLKYFFNTPSNPLDDPVSSESAAFAMNPNQQYQAPDLGHPWPRSSEIYQLIDANLVKIQERQAHTTRPLDKLATWTFVNVTDQEIRREIAQLIHLTRSRLSMTARQIQKMRLDKYANAIGAKPELVSENETPSPNDAVVAKTTPAVGPKASTPLQGSFHSSPSGIKKSIHPLHIPEIRLEIGRYLKESVLARCASVCKDWNQSFAPLLYSVVELTGKPGANPPLETLRRHEALIKSMSVVMNRLDLVYFHLLLSNLKTLKLDFNFPSTAIEPMIRNNRGIRFLKLSGIPTNDQSMLWKSVASLPHLEELSILNQSVNDKNELWGACSRLNKLTLIFSGFKKLLASTTTGTPLEQAADFNLLRDLTISKWKICPSVQLMLIMKCQNLERLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0E4</accession>
    <name>A0A9P6T0E4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_009910</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000637">
        <property type="protein sequence ID" value="KAG0015339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0E4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24362:SF309">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24362">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE NEK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0015339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="188" mass="20806" checksum="6D8F435F67D018F1" modified="2023-09-13" version="1">MGRRSGTGLNKQPMSPPCCLGNIFTVQEIRSITHTVVLGTQALHKEGYSHKDIKTADILFSRGHGLLCDFGLCSQIDQLLQNQFFGTQDYVSSEARRVGCHRECDYIRGDVFSLGAVLYELATGPVLSKVINQGLNWQRIAEFGGWTLAGYCKEWSMTLRSAGALIRSRAVHCGPYASSVIHLERVKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T171</accession>
    <name>A0A9P6T171_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Proteasome regulatory particle subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RPN8</name>
        <name evidence="6" type="ORF">BGZ80_008046</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M67A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000425">
        <property type="protein sequence ID" value="KAG0017670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T171"/>
    <dbReference type="OrthoDB" id="10256771at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008541">
        <property type="term" value="C:proteasome regulatory particle, lid subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08062">
        <property type="entry name" value="MPN_RPN7_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.140.10:FF:000004">
        <property type="entry name" value="26S proteasome regulatory subunit rpn-8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024969">
        <property type="entry name" value="EIF3F/CSN6-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033858">
        <property type="entry name" value="MPN_RPN7_8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10540:SF7">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10540">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13012">
        <property type="entry name" value="MitMem_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0647">Proteasome</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MPN" evidence="5">
        <location>
            <begin position="19"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="292"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0017670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="336" mass="37513" checksum="C2CB97E55C6A7631" modified="2023-09-13" version="1">MSPTNSTNTPVAVVQSSLVTVHPLVLLSVVDHYNRVAKNTKKRALGVLLGQAHGNKVNVANSFAVPFEEDEKDPSVWFLDHNYVEAMNDMFRKVNAKERMVGWYHSGPKLRASDLEINELFKKYTPNPALVIIDVKPTDLEIPTDAYFAVEEIRDDGTATTKTFVHVPSEIEAEEAEEIGVEHLLRDIKDNVVGTLSNRVGDQLRSLKGLQQRLEEIQEYLGKVVAGSLPINHQIIYNLQDIFNRLPNLEDPDTIKSFSVKTNDQLLVIYLSSLIRSVIALHNLINNKIENKRAEEELDGIDKDGKQETATEGDASKDGKDTKGSKDSKNGKETSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T172</accession>
    <name>A0A9P6T172_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_009302</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000543">
        <property type="protein sequence ID" value="KAG0016320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T172"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="entry name" value="Intergrase catalytic core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="DNA breaking-rejoining enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="572"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="578"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="616"/>
            <end position="626"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0016320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="633" mass="72881" checksum="D825BCB5FB5C9EB2" modified="2023-09-13" version="1">MTPETPDDIEGFHEEENMVSGIRNALDTAPQATKDHRYSKKTRSIYQGHIERGKKYASKFQEMEDAFDKISHATPMMLRAFVSFQCQENNFSHKTAEGIRSAFKQYFQETFGCQGNTWKCDEDGNWSGNPVFDPPFVEYMASLKNRDGRSGVSKQSLPMSYNDMKGLMDYLQKEDTIDQHTEGLCLLFQAFATTGFTLWTRNEELLRLQGKDIERNLLSDKGTPYLTITLTFRKDNQADNSREKNARPLHPDDYLFPCLDSKGRVKIKEPFSHSLIQSLLDTFTNEAGLLAHRNGRFGIHCFRRGGAQYRFMFAEEKWSLKAVKWWGGWPEGERTGTIMRYLLDEFVRYESGFGDMLSPVRNDSKHSLFMGGAGITEPVTQLSLGIALEGQRREIDASISSTKAELRTELQQLHRLVSNVEDSLVRKLQSIIYGLPGILEAGVPQVSHQQGEQEREIQVLAQKEKQTRKQGQKSASDISLAPRIPDISNWREAIRQWDEGDINKGCPMPLKMWTASMRKSDPSKYSARKLIATEFNFLSRSELAMKEVHGGALNLVRDLIRSIREAKRQRKIYREGQEDGEEEEEEEEVEEEEEEEEEELEEDDDDDGDDDDEEKEKEKEEVEVLVRTKRRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1A0</accession>
    <name>A0A9P6T1A0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Long-chain fatty acid-CoA ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">FAA4_2</name>
        <name evidence="7" type="ORF">BGZ80_009179</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a long-chain fatty acid + ATP + CoA = a long-chain fatty acyl-CoA + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:15421"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57560"/>
            <dbReference type="ChEBI" id="CHEBI:83139"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.2.1.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000528">
        <property type="protein sequence ID" value="KAG0016500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1A0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004467">
        <property type="term" value="F:long-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035336">
        <property type="term" value="P:long-chain fatty-acyl-CoA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272:SF83">
        <property type="entry name" value="ACYL-COA SYNTHETASE LONG-CHAIN, ISOFORM J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="6">
        <location>
            <begin position="94"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00036813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0016500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="655" mass="71902" checksum="F24DE9B5D03C78DC" modified="2023-09-13" version="1">MTKCLTVEVGPNDVQGETRIRRSATSPDELVSAPSDDIKTLYDVIQHSARVRPNLNALGRRKLIKMVEEEKEITKIVGGEPVKEKKTWRYFKLSGYNWMTYKDTKIVVDNIGAGLRSLGVQPKDKITVFGATSANWILFAHGSFSQSCTIVTVYDTLGEEGLLHSMNEAEVATAYTNADLLNTMKNVIGRCPTLKRIIYDGDAKPADVISLKETHPHIQLTTFEELKQLGVDHPVEAVPPQPEELCCIMYTSGSTGNPKGVLLTHANLIAAIGGVNTILTKYIYEGDVLLAYLPLAHVLEFLVENVCIYWGVSLGYGTVRTLTDASVRECQGDIKELRPTLMTGVPAVWETIRKGVVSQVNKGSPLVQSIFNAALNAKAWCMDNNLGAVTGIFDTVVFNKVRQQTGGRLRYTLSGGAPISEETQRFLSTALCPVLQAYGMTESCGMCAFMTPDAFSYVGVGSPVPLWIRGPSITSGYFKNAEETAATLTPDNWLKTGDIGEWHPDGTLSIIDRKKNLVKLSHGEYIALEKLESIYKSTAYCNNICVYADSMQSKPVAVIVTSEPRILELAKSKGIEGKDFAELCKNKDIIKGVLDACLATAKRAGLKPAEFVQGVYLEHEEWTAQNGYLTAAQKIKRKEINQAYSVQIKEIYGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1C5</accession>
    <name>A0A9P6T1C5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008303</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000446">
        <property type="protein sequence ID" value="KAG0017406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1C5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="143"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0017406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="313" mass="34647" checksum="175C5BFEF4A40B8D" modified="2023-09-13" version="1">MSVPNDGVKIRVPPPSVINSVFIYLLFGPFLLDLPSVISSGTFLAQKKYTKANTAIAVHFLTLGGVLLIATIIYYFTLDQLTKAMAEYTVPSELTLVHVGVSSNVEFSGGQTFTLSPPTEREKEEDEIWDTSLAKARHRLISIRNAGTAMLSFYVIIYSIYGISRPLIHSHIVWNVIFCLVFNLDPGTPTIYAYFIFSILYHINARSSCLPQTDPLPRPPMVHIPASRPSRPRSDSYLFDLRRPSVAGVGPSIPRRSPSVRSVARSMDLHSLSRADTITDKNNHLDQGQAPRNHAVVNMESTLPTQKGIATPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1Q7</accession>
    <name>A0A9P6T1Q7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_007400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000378">
        <property type="protein sequence ID" value="KAG0018248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1Q7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myb-like" evidence="2">
        <location>
            <begin position="76"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="2">
        <location>
            <begin position="219"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="2">
        <location>
            <begin position="456"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="356"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="541"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="148"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="391"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="411"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0018248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="561" mass="64637" checksum="773FDD0F0E184BA0" modified="2023-09-13" version="1">MTPDSTSFASSTAYRHHKKRSSSTFSFQSRSHMDTTHDNIYNNCSFNANHKQNSDYTGEDSPPPERSSKRKYIMRPWTNAEQESLYIAVEKLKLFGQWHEVKNRMNLDRTAKEIEEEYTRLYAEIPDSDQEWEMDHDHEQVPDHGVALPTPSLTDTSSTTPSARSSQDNMGILFDRSRELSSSSVPEREGEDDEEVDEEDIEDQYSRPQHNQHTPVDVRPARMVRVWTPEQSENLKNLIEVHFPGSYRINWVWVAAQMGNAFTRKQCKNKWEIMRRRMGTEDEINLLKRGYQEFGPSWGQIQEKYLPERSRGGISIMWDLLETREAEQQQNMKKSGPRAIRGASHGRYHSMSSMRAFHRPGGQKEPSPVFDSMGLKQDQQDPRPRRKRTVTSDIGSMDMSTHMFTPRSRNEGAQMQSHQPYTLQGNGVSRHTRHGSDITSLHSSETWGDRSYPMTWTEPLTRRLEELVQQNFPNHQKVNWAKISALMGNNPVVSRDQCKRRWYLISQNNSLQHHHNYKVGNLANDSSMAMETDQTETTTFGGTGSLAGAQPTNGHDAVGQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T235</accession>
    <name>A0A9P6T235_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Gfd2/YDR514C-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_006106</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000300">
        <property type="protein sequence ID" value="KAG0019252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T235"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040151">
        <property type="entry name" value="Gfd2/YDR514C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048519">
        <property type="entry name" value="Gfd2/YDR514C-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28083">
        <property type="entry name" value="GOOD FOR FULL DBP5 ACTIVITY PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28083:SF1">
        <property type="entry name" value="GOOD FOR FULL DBP5 ACTIVITY PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21762">
        <property type="entry name" value="DEDDh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfd2/YDR514C-like C-terminal" evidence="2">
        <location>
            <begin position="196"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="156"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF21762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0019252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="350" mass="39056" checksum="8EDECE72517DB64E" modified="2023-09-13" version="1">MSLPDSFLQLQTAIYEWTKECPQDLKGDFDTFIASPDYLDRPNIFFKGVEEPSHKWVALISMEGVESTRSLLQQRLRYQFMELHEARGVNFSQITPAPRMPVYGAYNKFLKDIVKANKINRTKAKVRGWTTTLDKAAEMVAAAPPDPSPPSPSPSPISAGSSLSSSSTAVSPSPSTSSFTNLTPKELSAASYGMWFISVDVESYERDHSKILEIGWSIWVSGVHKFVDRHYAVSEYRHLKNGKFVADRRNRFLFGETVWAPLKDSIAAFQQDLDTASKRNPEGLFALIAHDMASDEAYLKGMGVVFPEGMIQFDTLNLNCARVGDNVKTGLGKLLDELNIENYCLHNAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2V1</accession>
    <name>A0A9P6T2V1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_003131</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000181">
        <property type="protein sequence ID" value="KAG0021051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2V1"/>
    <dbReference type="OrthoDB" id="541276at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE PLK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345:SF87">
        <property type="entry name" value="TBC1 DOMAIN CONTAINING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="28"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="395"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="395"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0021051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="469" mass="50798" checksum="B7D8A759F84B3E11" modified="2023-09-13" version="1">MSALETPSDAWSLVGKSLPDQDRPQVSYHILDVLGYGTYGCIYLAKTSSTVPDFSPEYKAIKCLSKRGLSSTQLLIQRQEIDIHLSLSSANNGQHANVVDMSSVIETKDSLYLVMEYCSGGDLYDAITSQHAAAADSGMGFVAPALKIPGGRHLNVHSDNSVLDAMEQILSAVTHAHKHQVFHRDLKPENILVACDGSLKLADFGLATKDRVSSDFGCGSSFYMAPEQQPSSGPGHRRPYLPSKSDIWSLGIIFLNLKFGRNPWKISRASADPTFAAYAQDPKVLDGMFPELSASALHFLHRVLCIDPNERADCFEAMELLRRIDTIVIKDGSVDSVLDNSISATSSGVSTSSTSSSMSSSLSSMADSALMSLNGSQRGEIFHMEDDYGATTTVTTTSKKMQSSWSSTSSSKSWSDMDDEEEMDFSKPIEFEQQQDAIDFLAQSGFPTLTELVGAMTLPSSASSAIEVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T354</accession>
    <name>A0A9P6T354_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transmembrane protein 198</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_002969</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM198 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000176">
        <property type="protein sequence ID" value="KAG0021145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T354"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025256">
        <property type="entry name" value="TM7S3/TM198-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040236">
        <property type="entry name" value="TMEM198"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31247:SF5">
        <property type="entry name" value="DUF4203 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31247">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 198 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13886">
        <property type="entry name" value="TM7S3_TM198"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="144"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="168"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="213"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="TM7S3/TM198-like" evidence="9">
        <location>
            <begin position="42"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="309"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="309"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="322"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="356"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0021145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="410" mass="44057" checksum="BAFF1DE917259DDA" modified="2023-09-13" version="1">MPETSVVSFAADNITNSSLTDPFTTPSYLAPSTFTWEQGVYGALFLFFGAVEVLHGYKYIRFTMLVTGFLFWSSVAVMIMLIVDISTNAYQSSGVYFIIWLLVGIVGAIASFYLWHVGIILTGTYGAVVVVAVIFTAANVSSYAFRYSALAAVAIAGGYLTKRYERMAVILATSLGGAYCMMFGLDMFVQTGFRATFHVMLSQSSAAFDPVAGTWVMVAFVPVIAAFGVYWELKHHEQPVGSWWLGIGAKPLPPLPGEKPPRRCCGLLLALPFSKVRKLPAAGESDTTLVPPAETTSSRISRLLPCLGKRDKSTKKPADAATASSSANPDTSEPSPMTEVNSDSAAVEKPAAVEKLSTSPASGVGSSNIPIPFELEHFGVGHETIGHTGVHKVVINHEVREFSLDLDEQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3Q0</accession>
    <name>A0A9P6T3Q0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">OPT family small oligopeptide transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_011728</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000098">
        <property type="protein sequence ID" value="KAG0022582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3Q0"/>
    <dbReference type="OrthoDB" id="9986677at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035673">
        <property type="term" value="F:oligopeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004648">
        <property type="entry name" value="Oligpept_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00727">
        <property type="entry name" value="ISP4_OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22601">
        <property type="entry name" value="ISP4 LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="56"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="151"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="286"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="360"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="415"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="442"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="523"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="593"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="641"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="669"/>
            <end position="691"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0022582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="725" mass="82569" checksum="1364E66C9E1C27DB" modified="2023-09-13" version="1">MSEHKHEYDPTKEFVDEKVDIERQSVILEEEENSPIPEVAAIVSNKDDPSLPVLTFRFWVMGTVFTLILAFINQFFYLRNNPMTITSMAVQLLAYPIGKFMARVLPSGILNPGPFNVKEHVVIAMTANCAANTAYAVDITIIQKVFYRQDFGFLANIMLIFSTQMLGYGLAGVLRRYLVYPAAMIWPATLVQVAMFDTLHRDEDLAPGQWSRYKFFMIVTFGVFIYHWFPEFIFPVMGTVAWVCWINPKNLLLSQLGGSAGLGLGAITLDWNTIIAYLTSPLVAPWWAQANIMIGFVITAWILVPLTYYTNLWNSQRFPIITSKLYRENGEAYVVTDVLTNNQLNETKYDAYGSLRISGFFALTYGIGFAGLTSMITHTWLYHRHKLVAQWKQSREHSEDIHHKLMQAYPEVPDWWYLGIFAFMTAISIIGCEVYDYYLPWWAVLLAVALCCIFVLPVGLIQALTNQTPGLNIITEYVIGYILPGHPIANVTFKTLGYISMSQALTFVSDLKLGHYMKVPPRAMFWAQLFGTILAGIVNLLTADWLLKTQEHFCDPESDTFSCPNTNVFYSASVIWGVISPNRMFGPSSAYKVVNYFFLIGLVLPIPFFYLKRAFPNTWMENIHIPIILGATGMMPPAKPFHYFNWLVVGFIFQYYVRRYHPDWHLRFTYILSASLETGCCLTGLAIFAFFTSTKTEMAAWWGNQQPGELCPLQNEPTIPLGTPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T451</accession>
    <name>A0A9P6T451_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Eukaryotic translation initiation factor 3 subunit E</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">INT6_1</name>
        <name evidence="6" type="ORF">BGZ80_000430</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000109">
        <property type="protein sequence ID" value="KAG0022353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T451"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005852">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21378">
        <property type="entry name" value="eIF3E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03004">
        <property type="entry name" value="eIF3e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016650">
        <property type="entry name" value="eIF3e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019010">
        <property type="entry name" value="eIF3e_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10317">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09440">
        <property type="entry name" value="eIF3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016255">
        <property type="entry name" value="eIF3e_su6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01186">
        <property type="entry name" value="eIF3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="5">
        <location>
            <begin position="221"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="70"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0022353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="395" mass="45596" checksum="DF36C028E70A7E3D" modified="2023-09-13" version="1" fragment="single">MTDYDITLKMIPFLDLHLVFPLIEFLDIQELYTSSTLLEARYELALKTNMIDFMEKLSGELKEAGVTPAAGGLVKKREEILEQLENAQSEAQKVLDVIENPDVIAALRQDKLQNLQFLKDNYAMTPEMIQTLYTLGQIQYSCGNYGGAADMLYHYRVLSTDDTLGLSALWGKLASEILVGNWEVAFEAVQELKETIDKTHFASPLHQLEQRTWFLHWSLFVFFNHPKGGDAVVDLFFQPAYINTIQTSCPWILRYLTAAVITNRRRKTLLKDLVKVIEHESYQYKDPITEFVEALYVTFDFDLAKQKLVECEKVLESDFFLVSIQEEFIQNARCFISETYCRIHQKIDVAELSQTLNMSKEDGEKWIVNLIRDTRVDAKIDYKENTVLMNTNTTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MD49</accession>
    <name>A0A9P6MD49_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_008194</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004373">
        <property type="protein sequence ID" value="KAF9993304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MD49"/>
    <dbReference type="OrthoDB" id="2412073at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9993304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="107" mass="12162" checksum="1783CDC6F1774C65" modified="2023-09-13" version="1" fragment="single">MKKIDSCIQKMVVTSHNQGISFKNVASRLKIGVATVSKHHTQFSPDLKRQYSGLPGILSNADKREVTRNMISGERKAGKRVFKYSPREGYHVSNPIVRENYRSQSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MD90</accession>
    <name>A0A9P6MD90_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_008253</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004416">
        <property type="protein sequence ID" value="KAF9993165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MD90"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9993165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="83" mass="9692" checksum="307B602AB0D3BF1E" modified="2023-09-13" version="1" fragment="single">EGQEITTNNWIESWHRTLKQKLLGRERNVRADHLLCLLQGALDNFRVEYFKIRNGLMPPPLSKEDKLRKERAAAVPIEHALSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MDN1</accession>
    <name>A0A9P6MDN1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008032</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004239">
        <property type="protein sequence ID" value="KAF9993777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MDN1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9993777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="82" mass="9347" checksum="F37D4EC2E7A36416" modified="2023-09-13" version="1" fragment="single">MVMEIDNLKLQLNAIMVALNNQPQPRFRPRPYYRPPPQQPNQYRNPCDKLQHLNQNDRDRLIATGVASVAGNPVTLPGTVLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MEZ5</accession>
    <name>A0A9P6MEZ5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007253</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003684">
        <property type="protein sequence ID" value="KAF9996401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MEZ5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="84"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9996401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="106" mass="11937" checksum="4E5D43BAFC1AD6A9" modified="2023-09-13" version="1">MTRYETQEPRIRSNSITAAWSYIWRGSKTHQNQHLNGNPSTPSTNKHQTITEDDDEDRVLGKGIARKSCWELEDFTQTRAFNGTRPTAPTTTSITAPVCSGTDRNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MF73</accession>
    <name>A0A9P6MF73_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Nicotinamide phosphoribosyltransferase</fullName>
            <ecNumber evidence="6">2.4.2.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_007160</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; NAD(+) biosynthesis; nicotinamide D-ribonucleotide from 5-phospho-alpha-D-ribose 1-diphosphate and nicotinamide: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the NAPRTase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.12" evidence="6"/>
    <dbReference type="EMBL" id="JAAAID010003616">
        <property type="protein sequence ID" value="KAF9996814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MF73"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047280">
        <property type="term" value="F:nicotinamide phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD+ biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041525">
        <property type="entry name" value="N/Namide_PRibTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016471">
        <property type="entry name" value="Nicotinamide_PRibTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036068">
        <property type="entry name" value="Nicotinate_pribotase-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43816">
        <property type="entry name" value="NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43816:SF1">
        <property type="entry name" value="NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04095">
        <property type="entry name" value="NAPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51690">
        <property type="entry name" value="Nicotinate/Quinolinate PRTase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="2" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Nicotinate/nicotinamide phosphoribosyltransferase" evidence="8">
        <location>
            <begin position="35"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9996814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="308" mass="33403" checksum="7072EC9F7D6E224C" modified="2023-09-13" version="1" fragment="single">YPSAVATLSRRSRDLIQAAYDKSVDPDNFWTLESRLHDFGFRACTSVEQSVIGGTAHLLNFTGTDTLSAAYYAQFELNAGEPVASSIPASEHSVMTSFRTEKEAMEAMIQNFGEGVFACVMDSYDYQRALDNVLPAVASFKLEKGGFLVLRPDSGDAVDSVLAGLRAAETVFGCDINQKGYKVIRGCGVIQGDGINYETLGRILNAVLEAGYSAQTCAFGMGGGLLQKLNRDTMSFATKLSHIVYADGSKRDVMKHPKSDSDKISLPGILDVVRNEQGIPIVYPRAENGVPHKDNILQTVYDHGKVPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MFC0</accession>
    <name>A0A9P6MFC0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Squalene epoxidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_007288</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Microsome membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003701">
        <property type="protein sequence ID" value="KAF9996310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MFC0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004506">
        <property type="term" value="F:squalene monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050562">
        <property type="entry name" value="FAD_mOase_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013698">
        <property type="entry name" value="Squalene_epoxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356:SF2">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356">
        <property type="entry name" value="FAD-DEPENDENT MONOOXYGENASE ASQG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08491">
        <property type="entry name" value="SE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Squalene epoxidase" evidence="2">
        <location>
            <begin position="64"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9996310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="191" mass="21847" checksum="9087F8F25E14C10C" modified="2023-09-13" version="1" fragment="single">AKELHFRNSEWGPESIDDMLDQFQDFPCAFGGTMKEIFDATPRNLISKVFLEEKVFQTWYNARSVLIGDACHKLLPGAGQGAMTAMKDAVVLANCIYNMKDLSDESIKTAFASYYRQRYLEAVNITKLSARSTKVMFGHKWSDRLVRKVILNFLPGWIKMKTSQEAFMIRPQINWLPLTKSRGSGRVLPQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MGC5</accession>
    <name>A0A9P6MGC5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4604 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_006808</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003383">
        <property type="protein sequence ID" value="KAF9998328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MGC5"/>
    <dbReference type="OrthoDB" id="2553298at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027911">
        <property type="entry name" value="DUF4604"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15377">
        <property type="entry name" value="DUF4604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4604" evidence="2">
        <location>
            <begin position="13"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="215"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF15377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9998328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="254" mass="27982" checksum="226529B14BFF6996" modified="2023-09-13" version="1">MSDKKVTPHQMRKGLTYVAQGPDFMRMLTGQSSSAANNDPRNPYKKPIGIEAKFQTEEEDDDDETAHDILNEREEERPTVVVLKDGKHLDERQVRNVLKNLPPGLSEAEIQKRLAEEMDKVDKDDGDDDEDDDDDDDQEPVDANGKILFRRPKGSKIKAKKQSNTTSSTNKRQTLEEIISEETAAKANALKRKAGAGPGPKGANSADKNSKKEGNSNNGGNNNSSNSDSVGLAKKKKQKIAKSAMSLLSFDDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MGD0</accession>
    <name>A0A9P6MGD0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006934</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003467">
        <property type="protein sequence ID" value="KAF9997729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MGD0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="443"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9997729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="549" mass="59886" checksum="61FA2C8393BA1F9A" modified="2023-09-13" version="1">MWLRDSGGKFRSLFASGQEVNGLANFSGWHTTAIAFSATLFALGFSSTLLTVLFSTEPQFIDVFANNIVITAPIWNASYNATALLSREYAPDAASGFVNLLSSTQKLNLTAFSTERDPEPTNVTALKIYTSVTTDNGTTTMQSDYLSMLDAYSSCVGLVVEYQNTSNGAFRGNPDACGKGQYGFGIDARLRFGRGSAEIYLTADSWGQLTWQINSVPTAKIQQREILTQINGSTLRVSETYSTFDSVATTTYDPAGVQKLCESIMGVHRDSFDAGLCSNMTIDDVFSFHAMDLQYNEEDNAMMVRYCSVNCESSTYPGIKDGSGDDNVFYPTPAGSDMLSIKGTGAMYYVNITKEQNTVLQVNIASSASVQKSVPNQAVGELSSQVTDFSMIHTDTSGVPGAQTLYTALLAKTLSVWQKPQIRAPVGQYSTTDSRPWIRTRTLVIAVVISLVGLVLALCIERWFLLPYYTTTFMANVRAATSAEGTPKNVFAEIRESGKEGEPAYVTLNSLRLVLERSEEGAEKDYLISGGWQWGPVEMEAPRTRPLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MHE6</accession>
    <name>A0A9P6MHE6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">HRR25_2</name>
        <name evidence="14" type="ORF">BGZ80_006240</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010003071">
        <property type="protein sequence ID" value="KAG0001101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MHE6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14125">
        <property type="entry name" value="STKc_CK1_delta_epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000159">
        <property type="entry name" value="Casein kinase I hhp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000538">
        <property type="entry name" value="Putative Casein kinase I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050235">
        <property type="entry name" value="CK1_Ser-Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11909">
        <property type="entry name" value="CASEIN KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11 14" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="9"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="303"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="303"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="330"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="376"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0001101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="387" mass="44750" checksum="4A115F345873A8AE" modified="2023-09-13" version="1" fragment="single">MELRVGNKYRIGRKIGSGSFGDIYLGTSIVNGEEVAIKLESIKAKHPQLEYEARVYKTLAGGIGIPFIRWFGTECDYNAMVMDLLGPSLEDLFNFCSRKFSLKTVLLLADQLISRIEYIHSKNFIHRDIKPDNFLMGIGKRGNQVYVIDFGLAKKYRDPKSHLHIPYRENKNLTGTARYASINTHLGVEQSRRDDLESLSYVMMYFCRGSLPWQGLKAATKKQKYDRIMEKKMTTSTDILCRGFPQEFAIYLNYVRSLRFDDKPDYSYLRKLFRDLFVREGFQYDYVFDWTIYKYEKESTRNQQQMAMQQSAAQPAPPPEERYPPYYQSTRTTRNDQQASLNANPPLSGMEQAPPVRRRLQVGAPPTSMPQAGMDHGNDPRVNPSDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MJ38</accession>
    <name>A0A9P6MJ38_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Heat shock protein 70</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_005768</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002836">
        <property type="protein sequence ID" value="KAG0003582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MJ38"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.34.10:FF:000012">
        <property type="entry name" value="Heat shock 70 kDa protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0003582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="206" mass="22772" checksum="DB7C7556BB8FFD0E" modified="2023-09-13" version="1" fragment="single">GGVMAVVVPRNTAIPTIKKKTFTTTEDGQTTVQFPVYEGERPMTRDNNLLGKFELSGIAPMPRGTPELECTFELDANGILKVTAMDKATGRKANITISNGAGRLSAADIERMVSEAEKFKDEDRKNEEIVQSKQELESYVYQIQGTLNEPNVSMKLKRGDKKAVEEALEEAMAALQIDELAEKDTFVLAQRKLKRSVTKAFASLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MLM7</accession>
    <name>A0A9P6MLM7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_004841</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002423">
        <property type="protein sequence ID" value="KAG0007299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MLM7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="16"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="83"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0007299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="395" mass="43251" checksum="50D5DF7FA56A93ED" modified="2023-09-13" version="1">MERHLKECLHGRGSDDDYSDDEYVTTGDEDMDKPLCDDDGENLGSGFSRVTKREVLEGALKRFQKERGAGGDSDDASDDKNKSPGSSDGGDIFSDSRHKKKPKTSGEQSADYNFKQGLEYYLGENNRPLDYPKAKELFLKAADLGNTDSLNYLGLIYDNGFGVTKDILKAKEWFEKGASQGNPRAQNNLGNMYKHGDGGAKDYSKAVELFKKSANQEYGPAMNALGMMYRDGLGVTQDYAIAVQLFHMAILAKNVAAMNSLGLMQQSGRGVPQSWTEAAKFYQLGAKKGCSNAKANLGFLYRAGFGVPQDYSKALELLREAASEGNGNGQNHLAYMYQYGYGVPRNYSKAAELYQKAADYGHADALANLGVLYENGYGVPRDMSKTTMLYAEAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MLU5</accession>
    <name>A0A9P6MLU5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_004656</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002352">
        <property type="protein sequence ID" value="KAG0007439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MLU5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022185">
        <property type="entry name" value="DUF3712"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046368">
        <property type="entry name" value="Tag1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35895">
        <property type="entry name" value="CHROMOSOME 16, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35895:SF1">
        <property type="entry name" value="LIPID-BINDING SERUM GLYCOPROTEIN C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12505">
        <property type="entry name" value="DUF3712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0007439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="448" mass="46615" checksum="FA53F5CB8CAEE361" modified="2023-09-13" version="1" fragment="single">VDIGLITGITLNQLSMDFTTSNAYAPTLSSSNLVASMISIPGITLPISSIRQDVLIADNTNQIGTFSSDWAPSSVSGGSLKTTIPTSTFNVFSNSQAAFGTFISSIASQETYALTLKGSVDAKLNLGIFGTMTIPDIGFDANVPIAGLNGLKVIGYTYLLSTTFSTTGNIGLGVIVNLPNPSKLTLNLGDVSFSTASVDGFVGYSTIKGLTLVPGNNYVIATTNLDNTQPAANKIFSSIYTSNVTLTLTGYSGTSSNAALNAGLASMSSQMTIPQAFAGAVMSQAPYKNWSIKVNSGVTDRTKVFTVTTTFQSPYYGMPVEIIALQDANKLSAAQTVGISTGNSQLFTFQSISTINVPGTGSTTASFNVALPATFGNKTLSKWQSFVDFANTNGYITVALTALPTVVVDNDGVQRSVDWGASATKIPTVNIKTGSDFASILDVIPNFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MM40</accession>
    <name>A0A9P6MM40_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Alpha-1,3/1,6-mannosyltransferase ALG2</fullName>
            <ecNumber evidence="12">2.4.1.132</ecNumber>
            <ecNumber evidence="12">2.4.1.257</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">ALG2</name>
        <name evidence="15" type="ORF">BGZ80_004568</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 12">Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 12">
            <text>a beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + GDP-alpha-D-mannose = an alpha-D-Man-(1-&gt;3)-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + GDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:29515"/>
            <dbReference type="Rhea" id="RHEA-COMP:19511"/>
            <dbReference type="Rhea" id="RHEA-COMP:19513"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:58472"/>
            <dbReference type="ChEBI" id="CHEBI:132510"/>
            <dbReference type="EC" id="2.4.1.132"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10 12">
            <dbReference type="Rhea" id="RHEA:29516"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 12">
            <text>an alpha-D-Man-(1-&gt;3)-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + GDP-alpha-D-mannose = an alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + GDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:29519"/>
            <dbReference type="Rhea" id="RHEA-COMP:19513"/>
            <dbReference type="Rhea" id="RHEA-COMP:19515"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:132510"/>
            <dbReference type="ChEBI" id="CHEBI:132511"/>
            <dbReference type="EC" id="2.4.1.257"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11 12">
            <dbReference type="Rhea" id="RHEA:29520"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 12">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 12">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the glycosyltransferase group 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.132" evidence="12"/>
    <dbReference type="EC" id="2.4.1.257" evidence="12"/>
    <dbReference type="EMBL" id="JAAAID010002314">
        <property type="protein sequence ID" value="KAG0007522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MM40"/>
    <dbReference type="OrthoDB" id="448893at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004378">
        <property type="term" value="F:GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102704">
        <property type="term" value="F:GDP-Man:Man(2)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03805">
        <property type="entry name" value="GT4_ALG2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027054">
        <property type="entry name" value="ALG2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45918">
        <property type="entry name" value="ALPHA-1,3/1,6-MANNOSYLTRANSFERASE ALG2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45918:SF1">
        <property type="entry name" value="ALPHA-1,3_1,6-MANNOSYLTRANSFERASE ALG2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="466"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyltransferase subfamily 4-like N-terminal" evidence="14">
        <location>
            <begin position="35"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase family 1" evidence="13">
        <location>
            <begin position="233"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00045103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00045104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU367136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0007522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="483" mass="53999" checksum="05568BB5F3EC0B3F" modified="2023-09-13" version="1">MASISEATSSTTTDHSASEPFTPLRVAFIHPDLGIGGAERLVVDAAVGLQNRGHNVVMYTSHHDPKHCFEETRDGTLTVHVGGNTIVPRTILGRFYIICAIFRNLHLAWNMLLLNYDAPSKEKFDIIIVDQLSVSIPLLRLTGAKIFFYCHFPDKLLTKRESLLKKIYRVPVDFIEELTTGMADTIVVNSKFTANIFKESFKTLRQVPEVLYPSIQFDKFDRVVEASSPEIKILTPSTNKITFLSVNRYERKKDINLAIHAFARLLKSDNIGISTQQSIRLVIAGGYDTRVVENVEHHLELVQLAEKYGLKTWTLSAGQTDKAVPEDTQVLFLQSISDAQKLFLLQTSRALLYTPTNEHFGIVPVEAMYMKCPVVAVNSGGPTESILNEVTGYLCPAEEDIWANTLRTLLEKSEEELKAMGQAGHDRVVGLFSLTAFVTKLNGILMELYKKPSTLESYGLSGSMRPLLIFTVLTVVLAVMLYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMH3</accession>
    <name>A0A9P6MMH3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_004214</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002173">
        <property type="protein sequence ID" value="KAG0007801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004709">
        <property type="term" value="F:MAP kinase kinase kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000196">
        <property type="term" value="P:cell integrity MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000182">
        <property type="entry name" value="MAP kinase kinase kinase mkh1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000387">
        <property type="entry name" value="Serine/threonine-protein kinase STE11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050538">
        <property type="entry name" value="MAP_kinase_kinase_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48016">
        <property type="entry name" value="MAP KINASE KINASE KINASE SSK2-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48016:SF48">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE BCK1_SLK1_SSP31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="1018"/>
            <end position="1283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="35"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="95"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="155"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="266"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="308"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="433"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="496"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="546"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="628"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="800"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="96"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="181"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="266"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="310"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="435"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="515"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="1047"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0007801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1300" mass="141674" checksum="62F212BD24A72814" modified="2023-09-13" version="1">MSPGTSTTSLYSIPNHNNSNANLVQSFPTEINTVQSSFDQDTRQPVKYHRSPAEEGPGSTSVTPMTLPQPALGQLRPSIDALESLEDYELPLEFVQQPSRSNNSPRLSDPDLKLPPSRLPTQVTIETTELGLKIPNIMPRQSSIAYSVSALRPNLNVPPQIVPRGSSREYSAANGLNVPQSGRGMSPVSPSSPGGHSYPYSNRAQDSSITAKDVPAAKNGPSLNERRNNPSVPHIQTQSLVDVHSTGQQNGHQNGQQNGRQQFYEKGLRPDHSGTHSDATVVGGTLGIGRRPSHKRNHSSADVIQYQPAPAAPPAAPPAAPAPSKPKSIQVTLDNESFKYVDIAGIDNAVMLKERIFSRMRILAEKNKYGIFETTELEDPVEEDASSRGPPLSDKELMDLITNADNKGSVKFLVTPVIPLLLPRDMDILNPKRNPGSSTPAQQHYINQGRNSPYQGPIITQDAGGYHQRERTTDSANHIYPDPYMAFVQPPDDIWNSVHPHHPLPDSKHPHNTGRLPQQGSSSALNTSPYGSYQQQVYRYVDNPAHPHYQADDARRPSVGTNSARTSPRFGPVINTSLGRIHKSGANSPGVDGSMNHSPLSGKRMLARNPNLSLVIGSNTDQDGKLVNHHLRNGDQSASPGGSLGYRQPRMASSHDSGSPNANYYEMNRSNHPGFGEVPMVASQSYSGNLNSSGLPASPLSAGAAKRGSFQQVTKYGSSHSNLNSPRSNDGGSGVDMHMTNNHENEGEYFWGERPPMEFLLENFGRFFQDHDLDHPILEFQQPIPNGGSPMISAAQPNLGIPGSVHGSSNALGKGQGVSPSLADGWGSSSTMSSGHEDSSPPQGGFHAGHRESIIHKKSIRIVAQEAKDRFSRQYSGSKVMRRKSTKMWGSRLAEVMPTNQTGPSVGLGAHEYDDEGPLSPVTGSPALVTKSSIADIVKEAALEHNIIPESPPETQDDSQEPIQGIDVSLEGLLLKHSHQQQQVQQRIVQVESGKVMDQSQQGIYQNPQSGTIKTFQYLKGGLIGRGSFGRVYHAFNLDTCEMIAIKQVDLPQTLSERNCDRLKTSVEALFSEMEVLKDLDHENIVQYLGFAQNEETANIFLEYVSGGSIESCLKRSGHFPEPVIRSFTRQILLGLEYIHSKKIVHRDIKAANVLVDEQGVCKISDFGISKRNAQSQGGYDENVGSLQGSIFWMAPEMVTSKAYGAKVDIWSFGCLVLEMFTGQQPWKGYAPQQALFTIGSSSAHPPIPENISEEGQRFLARCFTTDANLRPTASELLQDPFAVPPPNYNFNDYKEQSSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNN8</accession>
    <name>A0A9P6MNN8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Crinkler effector protein N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_003050</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Host cell</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001787">
        <property type="protein sequence ID" value="KAG0008787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNN8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043657">
        <property type="term" value="C:host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045379">
        <property type="entry name" value="Crinkler_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20147">
        <property type="entry name" value="Crinkler"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Crinkler effector protein N-terminal" evidence="4">
        <location>
            <begin position="7"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF20147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0008787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="120" mass="14028" checksum="91BC3F1BA445BE6F" modified="2023-09-13" version="1">MATQLMFWCLMKEVEEGFTIFPVYISSDEWVYILQKTIKTAKPNDLSHVDADKLILWRVEIPIVKDAVYKQDYEQSVNRFKLDRRNKMETSDKVHDYIPEAVSKTIQVIVELSKQGVCLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MP24</accession>
    <name>A0A9P6MP24_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Threonine dehydratase</fullName>
            <ecNumber evidence="11">4.3.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Threonine deaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BGZ80_003832</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-threonine = 2-oxobutanoate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:22108"/>
            <dbReference type="ChEBI" id="CHEBI:16763"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="EC" id="4.3.1.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 11">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Amino-acid biosynthesis; L-isoleucine biosynthesis; 2-oxobutanoate from L-threonine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the serine/threonine dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.19" evidence="11"/>
    <dbReference type="EMBL" id="JAAAID010002034">
        <property type="protein sequence ID" value="KAG0008119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MP24"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003941">
        <property type="term" value="F:L-serine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004794">
        <property type="term" value="F:threonine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006565">
        <property type="term" value="P:L-serine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006567">
        <property type="term" value="P:L-threonine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01562">
        <property type="entry name" value="Thr-dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000008">
        <property type="entry name" value="L-threonine dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1020.10">
        <property type="entry name" value="Biosynthetic Threonine Deaminase, Domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050147">
        <property type="entry name" value="Ser/Thr_Dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000634">
        <property type="entry name" value="Ser/Thr_deHydtase_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001721">
        <property type="entry name" value="TD_ACT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038110">
        <property type="entry name" value="TD_ACT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005787">
        <property type="entry name" value="Thr_deHydtase_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01124">
        <property type="entry name" value="ilvA_2Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006674">
        <property type="entry name" value="PRK09224.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48078:SF11">
        <property type="entry name" value="THREONINE DEHYDRATASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48078">
        <property type="entry name" value="THREONINE DEHYDRATASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00585">
        <property type="entry name" value="Thr_dehydrat_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="ACT-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51672">
        <property type="entry name" value="ACT_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00165">
        <property type="entry name" value="DEHYDRATASE_SER_THR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 11" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="6 11" id="KW-0412">Isoleucine biosynthesis</keyword>
    <keyword evidence="9 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="8 11" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ACT-like" evidence="13">
        <location>
            <begin position="386"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="35"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0008119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="545" mass="61015" checksum="178F52F796EF8816" modified="2023-09-13" version="1">MSPTTLSTGQPEAIATTTTTTTTKPFPPKYTPPYVNSNQFQTNSLSRSTSTDHLDHEYPDYLRLIITSRCYEILKQSPLTLAHNLSARTQNQIYLKREDLQDVFSFKIRGAYNKMAHLSEQEKQRGVIACSAGNHAQGVAQAANTMGIKATIVMPTPTPEIKSRNVKRLGSTVILHGNNFDEAKAECDRLAKAENYTNIPPFDDPYVIAGQGTIGAEILRQHNLEEIDVIFCTVGGGGLIAGVAAYVKRVAPHIKIVGCETVDANAMTLSLRAGYRVELKEVGLFADGAAVKIVGEEPFRLCQSFVDEMVEVTNDEICAAIKDVFEDTRSIIEPAGALAVAGCKKYLREHKLINKTCVAVTSGANMNFERLRFVAERSLLGEQKEALISAVIPERPGEFMKLYMHIHPLMVTEFSYRYDSDGKQAHIFMSFLCNQDRRKELPPIMKSIAAEDGMQVWDISDDEMAKSHARYMIGGRSKVEHERMFRFKFPERPGALLQFLEDMGKVLAGLQVPEKDNVEFSKFLARLNYQWVEETDNPLYKQFFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MP42</accession>
    <name>A0A9P6MP42_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA-uridine aminocarboxypropyltransferase</fullName>
            <ecNumber evidence="1">2.5.1.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_002668</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a uridine in tRNA + S-adenosyl-L-methionine = a 3-[(3S)-3-amino-3-carboxypropyl]uridine in tRNA + S-methyl-5'-thioadenosine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:62432"/>
            <dbReference type="Rhea" id="RHEA-COMP:13339"/>
            <dbReference type="Rhea" id="RHEA-COMP:16092"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:82930"/>
            <dbReference type="EC" id="2.5.1.25"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TDD superfamily. DTWD2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.25" evidence="1"/>
    <dbReference type="EMBL" id="JAAAID010001668">
        <property type="protein sequence ID" value="KAG0009171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MP42"/>
    <dbReference type="OrthoDB" id="408541at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016432">
        <property type="term" value="F:tRNA-uridine aminocarboxypropyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005636">
        <property type="entry name" value="DTW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039262">
        <property type="entry name" value="DTWD2/TAPT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21392">
        <property type="entry name" value="TRNA-URIDINE AMINOCARBOXYPROPYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21392:SF0">
        <property type="entry name" value="TRNA-URIDINE AMINOCARBOXYPROPYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03942">
        <property type="entry name" value="DTW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01144">
        <property type="entry name" value="DTW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="DTW" evidence="8">
        <location>
            <begin position="213"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="57"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="123"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="57"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="70"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00034489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0009171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="470" mass="52843" checksum="2A46C9DFD7943B16" modified="2023-09-13" version="1">MSTAGGQSVQFADLPDKILLAIFDHVVSFELRAEIQNDNGTLQDLNGSESQASVTVAESLPGSSGTDHVRKSKNKAKKARMAGLGARTLFSDRHWPTTDQKNLELIKVRREHQLKLLKTSVNDKDESIGSSNNMIEGRGSRTTSSGGSDDGVKEHDGDDSQEGGEDGQRKKQKRTKFYSRFEQRAHRRKFGSLDPELKYTPLAWTNTLWSWKRTYFGDCRFIESEDVKTPNRIASRQYCNCRVRIMILQHPRCQVSIGTIRILKLSFKYCQIIIGKDFKAGRSLELDQALEDPNCTPLLLYPSHSAIDIQALALEPSQPTNPSTPESNYETLALPSARGASYPYKLVIALDGSWSHAKIMYRCNPRLQQLTQIKFPNPPQSIYHDLKPEPKPTYTSTAEAVGQAVALLGWPESNHTDLSKEGQDKSLTNAQLLLEDLIRPLKIMIEIQDTIAQDQHKQVSQEIEVEQEHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPB6</accession>
    <name>A0A9P6MPB6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="9">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">PP1_1</name>
        <name evidence="12" type="ORF">BGZ80_003178</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PPP phosphatase family. PP-1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="9"/>
    <dbReference type="EMBL" id="JAAAID010001827">
        <property type="protein sequence ID" value="KAG0008676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPB6"/>
    <dbReference type="OrthoDB" id="1930084at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07414">
        <property type="entry name" value="MPP_PP1_PPKL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000007">
        <property type="entry name" value="Serine/threonine-protein phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050341">
        <property type="entry name" value="PP1_catalytic_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031675">
        <property type="entry name" value="STPPase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11668">
        <property type="entry name" value="SERINE/THREONINE PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11668:SF300">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16891">
        <property type="entry name" value="STPPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="11">
        <location>
            <begin position="121"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="308"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="320"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0008676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="331" mass="38023" checksum="EF29169DA7CA6833" modified="2023-09-13" version="1">MADTTNIDLDSIIERLLEVRASRPGKQVQLGEHEIRFLCTTAREIFMSQPILLELEAPIKICGDIHGQYYDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLEVICLLFAYKIKYPENFFILRGNHECASTNRIYGFYDECKRRYNIKLWKTFTDCFNCLPVAAIVDEKIFCMHGGLSPDLLNMEQIRRVMRPTDIPDTGLLCDLLWSDPDKDITGWNENDRGVSFTFGQDVVSRFLQKHDMELICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAEKKQKYSYGALGSGRPVTPPRGKKKKEMAKVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPN6</accession>
    <name>A0A9P6MPN6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribosomal protein S6 kinase alpha-4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RPS6KA4</name>
        <name evidence="4" type="ORF">BGZ80_002316</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001568">
        <property type="protein sequence ID" value="KAG0009508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24362:SF309">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24362">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE NEK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="399"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="1134"/>
            <end position="1399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="269"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="461"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="527"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="290"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="338"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="616"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="626"/>
            <end position="637"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0009508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1402" mass="149281" checksum="65F127985A0FAAFE" modified="2023-09-13" version="1">MTYMLGYDSQGSIVFNFVEQDTCSSNWSNATWTSLPYPGGGKPYHTEECFLTSTHHFAVQYEGGVAIWDHWARTWTYRDIPCAVTYPNNAAMVNQDSQALIDDILIQWEDSKGAAHLTGVQLYNDTVNACNELSTTNVPTDMKLAAAPDDGKTFFLFGPKGSCWYDITAATTLSSQPIQTTSECHSLPALNISVPRATNYDGSIYIFGKNDVGVGVWSVNTANGAPYSIVPLSQGAPISGDFSVANCGTGIIVYGGCASADQCSTNLQPGEAFPPNSPTPPAVIYVPGTSGSGGSGSGGSGSGGSGSGGSGSGGSGSGGSGSGGSGSGGSGSGGSGSGSWIPAPTGIPTGIPSGGPTVVPTVSSATTIGVATSVTAPGVLPSGGADTSSKTNGNNHTGAIIGGIIGCLCLIFLIALIFVFARKKRRERYPAVVEEEEVIQENYSSAHGDVPPIIPVPIFGNENETAEGKDLPGPTGVPTGDSSAPGPNGSGRFAPVPVPAPVPAPHHSHTGEILAGGLLAGGVLAAAAHHKKEEEEETEEVSNGHVVPVPAPIPETESSSDRDAFVPIPVPVPTSGNSDNQPSGPGGFFPPTTTTKTTTEETEEIEEVGPGTETSGGKKREEEKTTTVTSETTTTTRNGHRVFTTAGPGGRTVETEITENGPRHVLMGVIPGTTTVRTITQRTKTGEEVLIPVEAPQGDEREVITEHDEHGNLRYIIGGIVAGGLIGKALSGSDSESGSRITTVTSSTRIVTERTSTGEIRHVIVGGFSGNAIRVLTERTSNGETRLIPTNEPTGELHHVISERSENGDIRYIIGGIVAGGAIRTITQRTESGGETRYTIGTVTSTTRIVTERITTGEIRYIIVGGFAGNAIRVFTERTPSGETRLIATNDETGELRQVFTERSETGEIRYIIGGVITNVITRVIMGPRIVSERTSTGEIRYVIIDKYNGNAIRTKFEINEETGEYVHIPVKEPEGELRYVNEERTESGEIRKVVGGIITGNVTTTTRTIEGVNREGPSTSTQTRIVAEKNGSEVRYYHITNGPDGQELRTEVERTEDGGFRTLAGVIIVGAGATLIGNNQTTTTTRVVPGGTLTAAEQAANKTQITLKLSIMRYERADASQAVPNAAIGTVMFSKFKMLAAGDVNIEDTAYSHVEETKTQARRTVKWMKTEAHWKREAGMLQHLKSDRYIADLYTLYSLPTFAEYRYVSILGSFNCTLETYLKREQLSSIQVRQLTASLSDALRWCHEHHVVHLNIRPASFYLDGIPGQDGNGQLVWKLWNFGHARFVGETVDTSVTTVTYAAPEILNGRKKSDANVLSAVSMDRWSLGLIIYELHARKVYFTSNAFAEFQLTSEEGTKFEPALEAVREDDARQAIRGLLEVDPERRFTHETLREVYFGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPQ8</accession>
    <name>A0A9P6MPQ8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_002754</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001695">
        <property type="protein sequence ID" value="KAG0009081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPQ8"/>
    <dbReference type="OrthoDB" id="2416955at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038425">
        <property type="entry name" value="GAT_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="194"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="272"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="360"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="316"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0009081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="395" mass="44381" checksum="1A3DBD9C32486AAE" modified="2023-09-13" version="1">MTSTTSTWSSLFQGIPNSTPASHFYTEEAIQNDQLTADEIVEKAQSSANLLYEMVTALNEEHETLQSFKNNDILQTIFQECQEMTNYLSIRIWDDSDDNNTRYQVFNMAGSLAPQKTADEEAQIAAFISCNEQIQVAIKRFNEFKDFLSAKSLQETELIGERAYSSRHPLDDINYVIPGRIDSSSTYTAAAVALDNGDGDDDESEGSTHLRRSEQPLVWKLDPREDFKASQTKMKKTNYEEWRKNSLVRHMEKSPRNGVHGLVEDPYEIKPEMLSQDDTPKNDKSQDEGVEESAAAPVVEVDEDGLERINNRPQVEEEEEEEKEDEEEEDFKSVASDDSWEEIPAQIVEDFSIEGEVGAQGVDATSPSSSSVSSFTMVPAEASCRTPTPPGVREL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPY9</accession>
    <name>A0A9P6MPY9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">TLC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_002340</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001573">
        <property type="protein sequence ID" value="KAG0009492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPY9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="169"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="199"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="223"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="250"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="280"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="356"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="379"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0009492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="428" mass="49100" checksum="990BA695BB5DA078" modified="2023-09-13" version="1">MAPVALTSEHLHMFIVSCGIHLTYFYLIKTFVPFIGKDRKRLSWVLTLVTALMVSVLGPYATFGNIRTVFSEPIPYEMYNPYAVEGLRQVQRYDVLFQPSINSLTQWQDQTWNSNRLSEKTEEGESTTEYIMFYKAYDAMYNLSPSEWHSLRHSRWFFDLRHTPSDSSIAQAAVIFFACYLILDMACGALHYRERVTILTGWFHHTMYTGICYYTLITGESHTFASFLVIEVPTFIMGLGFLHKPLRNDMLFGLTFILFRILFDFALTHEMVMNRTGLTTISRIILLFKTCMNFKFLIDWINQQIRLRRKRASALAAVMCEMGVQTTEVKSGLDIPSPYKNGNGITAHVCQHQQQALSQQSKQGRLQNPQNVKRRASNGMLTECTSDSSSPLMLSPINSRHVFRNRNTRARAGGMLDDQSLPVVIAAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQ20</accession>
    <name>A0A9P6MQ20_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_002751</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001694">
        <property type="protein sequence ID" value="KAG0009086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQ20"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0009086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="54" mass="6405" checksum="71308AA25B959728" modified="2023-09-13" version="1" fragment="single">VALAHVQYMPSDRLYKLFQAYKRHYEHYTPATINDVDAARTPPPNDHTNVHRWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQN8</accession>
    <name>A0A9P6MQN8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Cytochrome b5 heme-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BGZ80_001550</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="12">Microsome membrane</location>
            <topology evidence="12">Single-pass membrane protein</topology>
            <orientation evidence="12">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13 14">Belongs to the cytochrome b5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001357">
        <property type="protein sequence ID" value="KAG0010361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQN8"/>
    <dbReference type="OrthoDB" id="260519at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.120.10:FF:000002">
        <property type="entry name" value="Cytochrome b5 type B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018506">
        <property type="entry name" value="Cyt_B5_heme-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050668">
        <property type="entry name" value="Cytochrome_b5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19359">
        <property type="entry name" value="CYTOCHROME B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19359:SF150">
        <property type="entry name" value="CYTOCHROME B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00363">
        <property type="entry name" value="CYTOCHROMEB5"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00191">
        <property type="entry name" value="CYTOCHROME_B5_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="3 14" id="KW-0349">Heme</keyword>
    <keyword evidence="10 14" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0492">Microsome</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="16">
        <location>
            <begin position="3"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00037877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00038168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU362121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0010361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="129" mass="13847" checksum="C6D529ABF4589F28" modified="2023-09-13" version="1">MAAKSFTQVELSQHNTKSDLYVAIHGKVYDVTGFIDEHPGGEEVLIDEAGRDATESFEDVGHSEEAREILSKLYIGEYKSDGAADTSKKTFASTPKPIPAADPTDSGSKIQYVVALAVVAGCVIWKVLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MR59</accession>
    <name>A0A9P6MR59_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C-1-tetrahydrofolate synthase, cytoplasmic</fullName>
            <ecNumber evidence="8">1.5.1.5</ecNumber>
            <ecNumber evidence="7">3.5.4.9</ecNumber>
            <ecNumber evidence="6">6.3.4.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="primary">ADE3_1</name>
        <name evidence="22" type="ORF">BGZ80_001761</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>(6S)-5,6,7,8-tetrahydrofolate + formate + ATP = (6R)-10-formyltetrahydrofolate + ADP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20221"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:195366"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the C-terminal section; belongs to the formate--tetrahydrofolate ligase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the N-terminal section; belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.5" evidence="8"/>
    <dbReference type="EC" id="3.5.4.9" evidence="7"/>
    <dbReference type="EC" id="6.3.4.3" evidence="6"/>
    <dbReference type="EMBL" id="JAAAID010001407">
        <property type="protein sequence ID" value="KAG0010131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MR59"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004329">
        <property type="term" value="F:formate-tetrahydrofolate ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004477">
        <property type="term" value="F:methenyltetrahydrofolate cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004488">
        <property type="term" value="F:methylenetetrahydrofolate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009257">
        <property type="term" value="P:10-formyltetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046655">
        <property type="term" value="P:folic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006555">
        <property type="term" value="P:methionine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006164">
        <property type="term" value="P:purine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00477">
        <property type="entry name" value="FTHFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01080">
        <property type="entry name" value="NAD_bind_m-THF_DH_Cyclohyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000006">
        <property type="entry name" value="Bifunctional protein FolD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000245">
        <property type="entry name" value="C-1-tetrahydrofolate synthase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001123">
        <property type="entry name" value="C-1-tetrahydrofolate synthase, cytoplasmic isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10860:FF:000005">
        <property type="entry name" value="C-1-tetrahydrofolate synthase, cytoplasmic, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.770:FF:000001">
        <property type="entry name" value="Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.410.10:FF:000001">
        <property type="entry name" value="Putative formate--tetrahydrofolate ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.410.10">
        <property type="entry name" value="Formyltetrahydrofolate synthetase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10860">
        <property type="entry name" value="Leucine Dehydrogenase, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01543">
        <property type="entry name" value="FTHFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01576">
        <property type="entry name" value="THF_DHG_CYH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000559">
        <property type="entry name" value="Formate_THF_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020628">
        <property type="entry name" value="Formate_THF_ligase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000672">
        <property type="entry name" value="THF_DH/CycHdrlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020630">
        <property type="entry name" value="THF_DH/CycHdrlase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020867">
        <property type="entry name" value="THF_DH/CycHdrlase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020631">
        <property type="entry name" value="THF_DH/CycHdrlase_NAD-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48099:SF5">
        <property type="entry name" value="C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48099">
        <property type="entry name" value="C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01268">
        <property type="entry name" value="FTHFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00763">
        <property type="entry name" value="THF_DHG_CYH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02882">
        <property type="entry name" value="THF_DHG_CYH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00085">
        <property type="entry name" value="THFDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00721">
        <property type="entry name" value="FTHFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00766">
        <property type="entry name" value="THF_DHG_CYH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00767">
        <property type="entry name" value="THF_DHG_CYH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0436">Ligase</keyword>
    <keyword evidence="18" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="16" id="KW-0521">NADP</keyword>
    <keyword evidence="13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="17" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic" evidence="20">
        <location>
            <begin position="5"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding" evidence="21">
        <location>
            <begin position="142"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00012859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00017592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00049033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF00763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF02882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAG0010131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="925" mass="99725" checksum="A77F92475F96A316" modified="2023-09-13" version="1">MAQIIDGKAIAQNIRNDIKAQIEEMRKTAPNFNPKLSIIQVGTREDSSVYVNMKKKSAKEAGMDFELFHLPSTITQFELLTRVQALNNDPKVHGILVQLPLPDHLDDRVVTEAIDPKKDVDGFHAINIGHLSKRASEPAFVPCTPKGVIELIKAAGISMSGKKAVVVGRSDIVGTPVFSLLTKNNCTVTLCHSKTTDLPGIIKTADILVVAIGSAEFVKGDWIKEGAVVIDVGTNAVEDVEYAVASKHASHITPVPGGVGPMTVAMLMQNTYLSAVRFFNEGRQRAINPLPLQLLDPVPSDIAIALAQKPKPIKYIAEELGILPSELELYGEFKAKVSLDLLERLSHRRNGRYVVVTGITPTPLGEGKSTTTVGLVQALGAHLNKIAFGCVRQPSQGPTFGIKGGAAGGGYSQVIPMDEFNLHLTGDIHAVTAANNLLAAAIDARMFHEKTQSDKALFSRLCPTKKGKKVFAPVMLGRLQRLGINKTDPSELTPEEVSRFSRLDIDPATITWQRVMDTNDRFLRKIEIGRNDTEAGHERMTGFDIAVASEVMAVLALSTDLRDMRERLGKMVVASSRAGEPVTADDIGIGGALTVLMKDAIKPNVMQTLEGTPMFVHAGPFANIAHGNSSIIADRIALKLAGIEPGETDDRMGYVVTEAGFGADIGMEKFFDIKCRTSGLVPDCAVLVATVKALKMHGGGPDVTPGKPLPEVYNTENLELLETGCDNLRKHIENAKKFGVPVVVAINRFTSDTDAEMALIRKIALEAGADDAVACDNWAKGGLGAVDLGKAVIQACSKPIDFKYLYDVNADIESKIETIAKEMYGADGIELSDLAKEKIATYTRQGFGNLPICMAKTHLSLSHDPTLKNRPTGFKIPIRDIRASVGAGFLYPLCGAMQTMPGLPTRPCFYDVDIDFETGNVVGLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MR85</accession>
    <name>A0A9P6MR85_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Hydroxymethylglutaryl-CoA synthase</fullName>
            <shortName evidence="5">HMG-CoA synthase</shortName>
            <ecNumber evidence="5">2.3.3.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">3-hydroxy-3-methylglutaryl coenzyme A synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">HMGCS1_2</name>
        <name evidence="8" type="ORF">BGZ80_001703</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>acetoacetyl-CoA + acetyl-CoA + H2O = (3S)-3-hydroxy-3-methylglutaryl-CoA + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10188"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43074"/>
            <dbReference type="ChEBI" id="CHEBI:57286"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.3.10"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the thiolase-like superfamily. HMG-CoA synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.10" evidence="5"/>
    <dbReference type="EMBL" id="JAAAID010001395">
        <property type="protein sequence ID" value="KAG0010180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MR85"/>
    <dbReference type="OrthoDB" id="1269963at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004421">
        <property type="term" value="F:hydroxymethylglutaryl-CoA synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006084">
        <property type="term" value="P:acetyl-CoA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010142">
        <property type="term" value="P:farnesyl diphosphate biosynthetic process, mevalonate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00827">
        <property type="entry name" value="init_cond_enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.47.10:FF:000008">
        <property type="entry name" value="3-hydroxy-3-methylglutaryl coenzyme A synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000590">
        <property type="entry name" value="HMG_CoA_synt_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013746">
        <property type="entry name" value="HMG_CoA_synt_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013528">
        <property type="entry name" value="HMG_CoA_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010122">
        <property type="entry name" value="HMG_CoA_synthase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01833">
        <property type="entry name" value="HMG-CoA-S_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43323">
        <property type="entry name" value="3-HYDROXY-3-METHYLGLUTARYL COENZYME A SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43323:SF2">
        <property type="entry name" value="HYDROXYMETHYLGLUTARYL-COA SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08540">
        <property type="entry name" value="HMG_CoA_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01154">
        <property type="entry name" value="HMG_CoA_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01226">
        <property type="entry name" value="HMG_COA_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Hydroxymethylglutaryl-coenzyme A synthase N-terminal" evidence="6">
        <location>
            <begin position="11"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="Hydroxymethylglutaryl-coenzyme A synthase C-terminal" evidence="7">
        <location>
            <begin position="184"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="92"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="3">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="258"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="263"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="267"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR610122-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR610122-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0010180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="454" mass="50629" checksum="1684847F2613C55A" modified="2023-09-13" version="1">MVGSVSSATYPPDVGIHALEFYFPSKFVDQMELEQFDGVSAGKYTIGLGQTQMAVCDDREDINSISLTVVQNLVEKHNISFKDIGFLEVGTESIIDKSKSVKTVLMSLFEESGNYDVEGIDTKNACYGGTAGVFNAINWIESSSWDGRYALVVAADIASYAEGPARPTGGAGSVAILIGPNAPIVFDQGVRSTHMNHLWDFYKPELASEYPTVDGHFSNTCYIRSVDACYSLFTKKFSKRNSPDQLTKIQDLDFLAFHAPNCKLVQKAFGRLVYNDMLQDPENDIYAPVKEHAKFAHSEESYYDKGLERGMMQFTKAEYEKKVIPSLYASTNVGNMYTASVWACLSSLLSSTPDEEIVNKRIGMFSYGSGSAATFFSLKVVSSTQKFRETLQIKSRLDQRVKVSPEVFAELLKLREETALLKDYNPVGDISTLVKGTYFLKRIDEKFRRTYLRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRT8</accession>
    <name>A0A9P6MRT8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11 12">Vesicular-fusion protein SEC18</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">SEC18</name>
        <name evidence="15" type="ORF">BGZ80_001015</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10 12">Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001225">
        <property type="protein sequence ID" value="KAG0011012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRT8"/>
    <dbReference type="OrthoDB" id="9982946at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005795">
        <property type="term" value="C:Golgi stack"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043001">
        <property type="term" value="P:Golgi to plasma membrane protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035494">
        <property type="term" value="P:SNARE complex disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19504">
        <property type="entry name" value="RecA-like_NSF-SEC18_r1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000026">
        <property type="entry name" value="vesicle-fusing ATPase isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000166">
        <property type="entry name" value="vesicle-fusing ATPase isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.40.20:FF:000012">
        <property type="entry name" value="Vesicle-fusing ATPase protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000187">
        <property type="entry name" value="Vesicular-fusion ATPase SEC18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029067">
        <property type="entry name" value="CDC48_domain_2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039812">
        <property type="entry name" value="Vesicle-fus_ATPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23078:SF3">
        <property type="entry name" value="VESICLE-FUSING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23078">
        <property type="entry name" value="VESICULAR-FUSION PROTEIN NSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="ADC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54585">
        <property type="entry name" value="Cdc48 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 12" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 12" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="14">
        <location>
            <begin position="335"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="14">
        <location>
            <begin position="616"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="67"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00056429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00068637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU367045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0011012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="820" mass="91373" checksum="D704BE94DB15A5B8" modified="2023-09-13" version="1">MNNFPNERGYNTSPNPGGAPRIPARPNPPPTNNVGGTYQPRSSYGAPPEPQYSSQNTFGQPAPRQPPHYQQQQQQPVFQPQPSKRMRAIQSSSERYALTNYVVANSQDFPSYTRYILVDHQFVFSINFEDDFPGGCLGFSKFQRKWINSSLNKEIDVQTWDPSMDGREVYLSTIEVEIGLLVKNNEFRGEFDAKEMGRVFISVFNNQVLTNEQALVLDFKDVRLVAIPKKVELVSSDALMNGMRGPDGQELPSISGFRGVLTQQTQVQFVKAQGFNIKLTGAARNKPAVTLIQPNFKFEDMGIGGLDKEFSNMFRRAFASRIFPPSIVEKMGIQHVKGILLYGPPGTGKTLMAREIGKMLNGREPKIVNGPEVLSKFVGQSEENIRKLFIDAETEYKDKGEDSSLHIIIFDELDAICKQRGSKNDNTGVGDSVVNQLLAKMDGVEQLNNILIIGMTNRKDMIDEALLRPGRMEVHMEIGLPDENGRLQILKIHTHKAMQNNLLGDDVDLIELAALTKNFTGAEINGLVKSATSFAFNRHVKVGTLAGTTGDLENMKIQRADFIGALDEVHAAFGSSEEELDACITNGIIHFSTQIDKILKEGKLRVEQVQHSERTPLVSLLLHGPPGAGKTALAATMAMESQFPFIKLISPETMIGMSEIQKVNAIHRVFQDSYKSPLSVIVMDDIERLLDYTPIGSRFSNTVLQALAVLLKKQPPKGRRLLVLTTTTRRHVLEEMDLMDSFSSEIYVENLRTLEEVNTVVKSLQLFKSDDDRRTAMATLAKSGIEAKLSISIKKVLMTIEKARQDSDLVGRFVSDMSIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRY3</accession>
    <name>A0A9P6MRY3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_000941</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001207">
        <property type="protein sequence ID" value="KAG0011110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRY3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0011110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="329" mass="36824" checksum="9DAE6EA4FE2DCB81" modified="2023-09-13" version="1">MRKAAAASKDKASKDILKVINGVKLALPMSRSVKDAEREIEVPDEAAESEELAEEKEEEEEKEEEEEEEEEEGDDDDDDKDAASVNSHDRSDDDDDDADDDNGNGGRFNSGIRQRRTGRSYEATKGTNHYDRSSGAVEQIPMQSRGNQPLRQRRQNPRRASESTAVSLDQGMKTKKAGQIYRDEERIIHRSRSETGDSTSKAQPHTAATQNGPPIQMHYISPSRTSTPPVPAKDNIQLLPKDKPHQRKEKKRETITSVAGSLSAIIAENLENIELDLGKKIDNDRRHIWTPTAHVVPKPLTPYCGFVNKDGEPKKPGDEGYYFFVGFKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRY5</accession>
    <name>A0A9P6MRY5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">H/ACA ribonucleoprotein complex subunit CBF5</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">H/ACA ribonucleoprotein complex subunit cbf5</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">CBF5</name>
        <name evidence="11" type="ORF">BGZ80_000767</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a uridine in mRNA = a pseudouridine in mRNA</text>
            <dbReference type="Rhea" id="RHEA:56644"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:14659"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>uridine in 5S rRNA = pseudouridine in 5S rRNA</text>
            <dbReference type="Rhea" id="RHEA:47036"/>
            <dbReference type="Rhea" id="RHEA-COMP:11730"/>
            <dbReference type="Rhea" id="RHEA-COMP:11731"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>uridine in snRNA = pseudouridine in snRNA</text>
            <dbReference type="Rhea" id="RHEA:51124"/>
            <dbReference type="Rhea" id="RHEA-COMP:12891"/>
            <dbReference type="Rhea" id="RHEA-COMP:12892"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the pseudouridine synthase TruB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001169">
        <property type="protein sequence ID" value="KAG0011322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRY5"/>
    <dbReference type="OrthoDB" id="10250002at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031429">
        <property type="term" value="C:box H/ACA snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000495">
        <property type="term" value="P:box H/ACA sno(s)RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990481">
        <property type="term" value="P:mRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031118">
        <property type="term" value="P:rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031120">
        <property type="term" value="P:snRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02572">
        <property type="entry name" value="PseudoU_synth_hDyskerin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21148">
        <property type="entry name" value="PUA_Cbf5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2350.10:FF:000001">
        <property type="entry name" value="H/ACA ribonucleoprotein complex subunit CBF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.10">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.10">
        <property type="entry name" value="PUA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012960">
        <property type="entry name" value="Dyskerin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002501">
        <property type="entry name" value="PsdUridine_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002478">
        <property type="entry name" value="PUA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036974">
        <property type="entry name" value="PUA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004802">
        <property type="entry name" value="tRNA_PsdUridine_synth_B_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032819">
        <property type="entry name" value="TruB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004521">
        <property type="entry name" value="Uncharacterised_CHP00451"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00425">
        <property type="entry name" value="CBF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003280">
        <property type="entry name" value="PRK04270.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00451">
        <property type="entry name" value="unchar_dom_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23127">
        <property type="entry name" value="CENTROMERE/MICROTUBULE BINDING PROTEIN CBF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23127:SF0">
        <property type="entry name" value="H_ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT DKC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08068">
        <property type="entry name" value="DKCLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01472">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16198">
        <property type="entry name" value="TruB_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01509">
        <property type="entry name" value="TruB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01136">
        <property type="entry name" value="DKCLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00359">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50890">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dyskerin-like" evidence="10">
        <location>
            <begin position="29"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="PUA" evidence="9">
        <location>
            <begin position="278"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="409"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="409"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="424"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="464"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00072225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0011322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="492" mass="55515" checksum="43D032D232E95991" modified="2023-09-13" version="1">MSPKSKSIEEAQRQGDFTIKPESSAPTLNTADWPLLLKNYDKLNVRTGHYTPIPSGCSPLRRELTEYIRYGVINLDKPANPSSHEVVAWVRRILRVEKTGHSGTLDPKVTGCLIVCIDRATRLVKSQQGAGKEYVCVLRLHDAIESEKKLAQTLETLTGALFQRPPLISAVKRQLRIRTIHESKLIEFDNDRHLAVFWVACEAGTYMRTMCVHMGLLLGVGGHMQELRRVRSGHMGEEDDIVTMHDVLDAQWMYDNTKDESYLRKVVRPLETLLTTYKRIVVKDSAVNAICYGAKVMIPGLLRYESGIEVNEEVVLMTTKGEAIALGIAQMTTAVMATCDHGVVAKIKRVIMERDTYPRRWGLGPKAQEKKKLIKDGKLDKYGRTTDETPEGWKKGYVDYNREDPVAPTTVAAPVAAPVAVKAQPEEEKKRKAADSSSESDSDKKEKKDKKAAKKVKSEEKKEKKEKKEKKEKKEKKEKKEKKAKKEDTDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSI6</accession>
    <name>A0A9P6MSI6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">SAM-dependent MTase RsmB/NOP-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BGZ80_000363</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001073">
        <property type="protein sequence ID" value="KAG0011877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSI6"/>
    <dbReference type="OrthoDB" id="6093671at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016428">
        <property type="term" value="F:tRNA (cytidine-5-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049560">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001678">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057285">
        <property type="entry name" value="Pre-PUA_NSUN2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057286">
        <property type="entry name" value="PUA_NSUN2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023267">
        <property type="entry name" value="RCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023270">
        <property type="entry name" value="RCMT_NCL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018314">
        <property type="entry name" value="RsmB/NOL1/NOP2-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22808">
        <property type="entry name" value="NCL1 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22808:SF1">
        <property type="entry name" value="RNA CYTOSINE-C(5)-METHYLTRANSFERASE NSUN2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01189">
        <property type="entry name" value="Methyltr_RsmB-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25376">
        <property type="entry name" value="Pre-PUA_NSUN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25378">
        <property type="entry name" value="PUA_NSUN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02008">
        <property type="entry name" value="RCMTFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02011">
        <property type="entry name" value="RCMTNCL1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01153">
        <property type="entry name" value="NOL1_NOP2_SUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51686">
        <property type="entry name" value="SAM_MT_RSMB_NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="3" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="SAM-dependent MTase RsmB/NOP-type" evidence="12">
        <location>
            <begin position="51"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="430"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="708"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="430"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="708"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="731"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="10">
        <location>
            <position position="309"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="169"/>
            <end position="175"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="256"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0011877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="758" mass="84197" checksum="724983956A675DAB" modified="2023-09-13" version="1">MGRRFSKRKNAPPRKERDPNASYVEVIKENAQMEEYYKAQKIMSEEEWPVFWGHLKVTLPTTFRITGTRSHAVEIRDTVKNAFVPHLSNISVDGVVANPPRPLAWYPDELGWHFDVPRTLLKKSPEYAKFHQFLVAETEVGNISRQEAVSMIPPLLLDIQPQHWVMDMCAAPGSKTAQIIEMVHAVEQHKVVPGGLILANDADYRRSHMLIHQTKRLQSPCLMVTNHDASMMPSLTLAPNKAGEVVPFEFDRVLADVPCSGDATLRKNPMVWNSWTHGGAMGLHQTQVNILQRGVQMLKVGGRIVYSTCSFNPMENEAVVAEMLNRANGTLELVDVTNELPLLKRRPGLSDWKVFTKEGQQVDKFEDVPTDAKGKFFPSMWPPENAGELHLERCLRIYPHLQDTGGFFVAVFKKTAPYVVPNPGRAAAAAEKAASASTSENKEQNAEEDTTTTGDKHKLDTAAGEEGSEPVKKARMTRAERFGAPGPKEEPFLFLDANNTDVELFSKFYGLDEDFPKDQFLVRSEGEKNKTIYIVSEAVKSILKSNDIHRLKVVNTGVRTFIRQDSNSPADCTFRIHNEGIAMMRQFVSDARVMAVQLEEVITLLQSPYPKITEFPEAVQERLTALPTGCCIFEFDPALEKDKDKPNPRWEGQGLTGFVKGKLVFPVWKAQVSFNMLLNKQERRSLAMRLGVDCVDSPHVVEGGAKGTAAKAKAAAAEAAASASASASEDATPEDATPEDSPMAEDDAAEGSEEEESL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSV2</accession>
    <name>A0A9P6MSV2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Coatomer subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BGZ80_000104</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001015">
        <property type="protein sequence ID" value="KAG0012245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSV2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030126">
        <property type="term" value="C:COPI vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22948">
        <property type="entry name" value="Coatomer_WDAD_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.470:FF:000002">
        <property type="entry name" value="Coatomer subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000010">
        <property type="entry name" value="Coatomer subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006692">
        <property type="entry name" value="Beta-prop_COPA/B_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047312">
        <property type="entry name" value="Coatomer_alpha_WD-assoc_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016391">
        <property type="entry name" value="Coatomer_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010714">
        <property type="entry name" value="Coatomer_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050844">
        <property type="entry name" value="Coatomer_complex_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056176">
        <property type="entry name" value="TPR_COPA_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19876">
        <property type="entry name" value="COATOMER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19876:SF1">
        <property type="entry name" value="COATOMER SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04053">
        <property type="entry name" value="B-prop_COPA_B_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06957">
        <property type="entry name" value="COPI_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23953">
        <property type="entry name" value="TPR_COPA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003354">
        <property type="entry name" value="Coatomer_alpha_subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="9" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="5 11" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="9"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="51"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="93"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="135"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="208"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="252"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="domain" description="COPA/B second beta-propeller" evidence="12">
        <location>
            <begin position="346"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="domain" description="COPA/B TPR" evidence="14">
        <location>
            <begin position="618"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="domain" description="Coatomer alpha subunit C-terminal" evidence="13">
        <location>
            <begin position="826"/>
            <end position="1229"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="1230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF04053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF06957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF23953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0012245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="17">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1230" mass="138576" checksum="135DCB94326ED873" modified="2023-09-13" version="1" fragment="single">LKMQMLTKFESKSNRVKGVAFHPKRPWILAALHNGSIQLWDYRMGTLLERFDEHDGPVRGISFHPSQPLFVSAGDDYKIKVWNYKTRRCQFTLTGHLDYVRTVYFHHEYPWILSCSDDQTIRIWNWQSRNCIAILTGHNHYVMSAQFHPKEDLIVSASLDQTVRVWDFSGLRKKNAAPGTVSYDESAHRASQQADIFGSTDAIVKYVLEGHDRSVNWATFHPTLPLIVSAGDDRQVKLWRMNETKAWEVDTCRGHTNNVSCTLFHQRQELIISVAEDKCIRVWDMSKRTAVQTFRREHDRFWALTAHPELNLFAAGHDNGLIVFKLERERPAYAVHQSNLFYIKDKYLRVYDYSNSQDTAVLSVRRTGSQFVQPRALSYNPAERAVLITSMVDGGTYELYNLPKDYGNEAREPANEGKRGTGNSAIFIARNRFAVLEKANQTITIRDLQNNSTKSFKTPSVVNEIFYAGTGQLLLSTPTSVILFDIQQRKTISEVTTPPVKYVVWSADMAYVALLSKHTITIASKSLEQTCLIHETIRIKSAAWDDSGILIYSTLNHIKYALPQGDNGIIRTLDQPIYLTRIKGKNVYCLDRDGKTRTIPIDPTEYRFKQALTKRNYDEVLQIIRNSNLVGQSIIAYLQKKGYPEIALHFVREDKTRFELALECGNLEVGLETAKVMDKEESWSKLAQEALRQGNHQIVEMCYQRIKNFDRLSFLYLATGNTDKLSKMLKIAELRGDSMSRFHNSLFLGNVEERIRLLREVGQGPLAYLTAKTHGMMEIANEILEESGLSPEDISDLPGQGTLLVPPRPLMRVHDSNWPQLAVSRSYFEGVFSGDMEGVAPQVPLTASEPEPQADQWGMDDEFSIPALDHKGASLAPIGNDALDIDGDGGWDLDADLAAELHAETGAIVAEDSGLAIPVAGQSEAEIWCQNSPLAADHVAAGAFESAMQLLNRQVGAVNFEPLKEHFLSIFQASRAIVTGNEGMPSIMLPVRRNPTESDQRRALPALIKNFQSMLSSDLQEAYRATTSNKITEACTLFRGILHSLLLTVVTQQSEAEEALQLVGVCREYILGLSIELSRREVQNDTSPEGIKRMLELAAYFTGVQLQPKHMIISLRTAMTACYKHKNLQSAQTFARRLLELAPPGQAATLARQIQQVAERNPRDEIQLDYDQYNSFVVCGISYTPIYRGSPSVQCPYCRTHFKPEFQGNLCTICDISRIGGTGTGMMVIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MT95</accession>
    <name>A0A9P6MT95_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CorA metal ion transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">MNR2_3</name>
        <name evidence="2" type="ORF">BGZ80_011663</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000967">
        <property type="protein sequence ID" value="KAG0012552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MT95"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010961">
        <property type="term" value="P:intracellular magnesium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12829">
        <property type="entry name" value="Alr1p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.20">
        <property type="entry name" value="CorA soluble domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044089">
        <property type="entry name" value="Alr1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045861">
        <property type="entry name" value="CorA_cytoplasmic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002523">
        <property type="entry name" value="MgTranspt_CorA/ZnTranspt_ZntB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21535">
        <property type="entry name" value="MAGNESIUM AND COBALT TRANSPORT PROTEIN/MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21535:SF51">
        <property type="entry name" value="MANGANESE RESISTANCE PROTEIN MNR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01544">
        <property type="entry name" value="CorA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143865">
        <property type="entry name" value="CorA soluble domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="457"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="459"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0012552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="578" mass="64687" checksum="54748824947F38EA" modified="2023-09-13" version="1">MSNQDPNPTGNHLRNDIAIALQDVDNTTTTSNHQNTHGSNASDATYTTSVINSYDYLQPGGPSHIHSSTFSPTSRNQSTIGLNGGYSPTLRSERLLAHQQSSSPYITRNDFPSNAMGYRGNGIDGTHTPIYQHHRNQHLFEQDQLGNNGMNIDYEGLDAAVREISLTEESICDQETLMGEQSPDKGGLEKAFSTGSASVLGNAARRRSSRKAGFYSERAPRSVGMIEATSLPKILVQASAQKSGDTNGPKVFSDLLKGGCFWIDILDPSNLDMQILSKHFHIHPLTIEDISTEEIREKYEVFRNYYFVCFRTFDQDYNSGSYLQPISMYSIVLRDGIITFHFRPTHHHLNVLHRLEQFHSLITLTPDWINYALLDDITDSFASPIQTIEYEVDSIDELVLLLRENETSDMLRRIGSCRKNVMMISRLLTNKAEVIRGLMKRFDDRYTVAMNNISPGPPAAAATQGGEAPSPNAAPSVVGTQQQQQQEQQEQLQQQQIIHSYHNGEIMLYLGDILDHVLTMLQSLYSYEKILSRSHSNYLAQISLEINQSSNRTNNVVGKLTFFASLIVPMTFVAGLWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTK1</accession>
    <name>A0A9P6MTK1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">cAMP-dependent protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BGZ80_011376</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.11"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.11" evidence="1"/>
    <dbReference type="EMBL" id="JAAAID010000906">
        <property type="protein sequence ID" value="KAG0012997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTK1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005952">
        <property type="term" value="C:cAMP-dependent protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004691">
        <property type="term" value="F:cAMP-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd05580">
        <property type="entry name" value="STKc_PKA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000005">
        <property type="entry name" value="cAMP-dependent protein kinase catalytic subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353:SF37">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT PRKX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="1"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="11">
        <location>
            <begin position="228"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="246"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0012997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="282" mass="32438" checksum="46E98D9CFDB5EC86" modified="2023-09-13" version="1">MKVLKKSEVVRLKQVEHINSEKLILSQVNHPFIVNLFTTFQDDRNLYMLLEYVIGGELFSHLRRAGRFPNDMTKFYAAEIVLAIEYLHERDIIYRDLKPENLLLDSQGHIKITDFGFAKRVSDRTWTLCGTPEYLAPEIIQSKGHGKPVDWWALGILIFEMLAGHPPFFDDNPFGIYEKILAGRIYFPAFIDSSAKDLIKKLLTADRTKRLGNLKGGSQDIRDHKWFRGVDWEGLEKRTVAAPIVPPHLHEGDTSNFENYPEAVDDGADQQGDPYRSLFSNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTL7</accession>
    <name>A0A9P6MTL7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Chitin synthase activator</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_011170</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000868">
        <property type="protein sequence ID" value="KAG0013287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTL7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="17"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="17"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="147"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="843"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="925"/>
            <end position="985"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="147"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="193"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="843"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="868"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="930"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="974"/>
            <end position="985"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0013287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="985" mass="108889" checksum="1681C08982592469" modified="2023-09-13" version="1">MRLTTRLSQFEFSQFSSSTVPLSCGYTMLNTTQQHLSQTQTLQSDNVDGLTSSIAPLSETDGIEPQIDIELAADSPPPVCKEHWDVSSPTDSGFELEPPGHDVLPYTTIGEQAIDTRMESLSITDSTNFITALSKKFSDQSIIDETAATSTETPSSQAEKVGGEPQDIDDSIRSTISSDHGSNGEALQSTPGPEDRSNDREKNTHHSTEVSIDTIPVDGLSTAQDQDKKEMDEDYKLGVSYYYGKGVAQDYSKAIEYFIKAAKQGHKDSHHKAAYMYDHGYGVEVDHAKAPEWYQVLADQGYTKSQYNLGLLYEDGRGVTRDYVKAAELFEMAAKKGYSKAQNSLGGLYRYGHGVTKDYSKAVELYEQAAIQGLPSAQYNLGTMHLYGNGTTQDFVQALHWLEKAADQGESKAVFKLGTMYQNGCGVAQDHTKAAELYRKAADLGQPIALSNLGSMCQKGDGVAKDYVKALELYEMAASQGDAKACYKLGHMYQNGHGVTQDYAKAVEWYLNGANLGDSRAQCSLGDMYEFGRGVDKDYSTAMEWYQEATGQGDCRAQFGLGIIYENGRGVTRDFAKAMEWYLKSASQGYTRAQHSLGYMYYYGRGVRRNYAKAAEWYQDAASRGHAKSQFSLGQMYEVGRGVTKDYEKAAKLYEEASSQGYVKAQYSLGLLYQDGNGKTKDCVKAEEWYLKAANGGDAKAQYTLGLMYQDGDGVSQDYSKAVVYYEMAGDQKHGKALCNLGVMYENGCGVTRDYVKAAEWYQKAARQGNDIAQCNLAFMYRNGNGVSQNYSKAVEWYKKAARQGYTKAQHELGILYHNGEGVPKDIQKAMDWWETASTRRLLGTSSTSASPTSPTSSAPPISPNPPTSTTSPNPSTSPNINFINRSNLVNPINLGNLSDLVNLNLTDLANLTNLVHSTNLAKPVNFTNHQPRQSQQPRQPQQPQQPQQPQQPRQSRHHQPHQPHQPQEHIQDRNQVSLTHTLQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MU80</accession>
    <name>A0A9P6MU80_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_011684</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000970">
        <property type="protein sequence ID" value="KAG0012529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MU80"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="76"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="258"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="32"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0012529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="362" mass="38238" checksum="939B4808BC58347A" modified="2023-09-13" version="1">MSSSYSSYSWTPPTSTVLSRSIITGVPTSVVTSKPSNSGSSQNFSTSPMASTAASYPSSSPTSVPSTSLGISVQTLLLVTIVGLIGLTIATVCSIHVIRRYRRRGVLERESGGQDPESNIGRVTSTYRPEDESDSASPPPQYRAIGGDRPYIDPNMVAAYQDTVFLNNNSVLESASSQQGLIGAPSAMTADDPNGPIITTATTTTTASSMNPIISNTIVATPSPVAAPIAGRDQSIIRHDLSGSSDIHNMGIRTPTLPTTATGVYSTNPNSQSTTEFRSTSSTLSHPEQSLLSVPATTSQNTAIRQPEGSPMTERVGNRRRSSILQPILNRFRSQGPPPYIPMSPEEIVPHLPPEYATAVSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUA7</accession>
    <name>A0A9P6MUA7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Zinc cadmium resistance protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BGZ80_010800</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000793">
        <property type="protein sequence ID" value="KAG0013855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUA7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005385">
        <property type="term" value="F:zinc ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006882">
        <property type="term" value="P:intracellular zinc ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="entry name" value="Cation efflux protein transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027470">
        <property type="entry name" value="Cation_efflux_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036837">
        <property type="entry name" value="Cation_efflux_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058533">
        <property type="entry name" value="Cation_efflux_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45820">
        <property type="entry name" value="FI23527P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45820:SF4">
        <property type="entry name" value="ZINC TRANSPORTER 63C, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16916">
        <property type="entry name" value="ZT_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160240">
        <property type="entry name" value="Cation efflux protein cytoplasmic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="Cation efflux protein transmembrane domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="35"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="78"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="112"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="277"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein transmembrane" evidence="10">
        <location>
            <begin position="11"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein cytoplasmic" evidence="11">
        <location>
            <begin position="343"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="139"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="207"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="139"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="156"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="236"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF16916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0013855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="516" mass="56415" checksum="A02FD431A3DD054D" modified="2023-09-13" version="1">MALLSRSGRIVLLLVLNVIMFLAEIIVGYKTSSLALIADAFHMLSDVLASVIALYAIRLAAKTEWRPTLSYGWQRAELLGALYNGVFLLALCFSIFLDAIERFFKPEDIDEPVLVLVVGGIGLASNLLGLVLFHDHGGHSHGHGHSHGHSHGHSHAKSEKSAASDKEFSSPENEVDGPSQGLYSLERISPLQEVSLQNLQQLALQVQRQVEDENEESTETEEHTPARPEAVVVSLDESHDSAHHGNHVGHDNHSHDHSDSGKNGKQPSGEDLNMKGIFLHVLGDALGSIGVIITALFIWKTDFSWRFYMDPVVSLLITAIIIRSAVPLVKSASFILMQGVPVGVEIEEIRRDIKAIPDVISIHDLHIWQLTNTKMVASLHVLVTNQESFERVSRVVKTIMHRAGVHSTTIQPEFPGMNPHHPQAFITKNSLRLRKATSGEELLAGGEFSSRATSVDAYSEGRLSEGHGPNEINATQGEIGIPEVHIIMDESNCTLLCVDGEQACDVGSCCTLPVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MV54</accession>
    <name>A0A9P6MV54_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_010803</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000793">
        <property type="protein sequence ID" value="KAG0013858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MV54"/>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016460">
        <property type="term" value="C:myosin II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000001">
        <property type="entry name" value="Calmodulin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050230">
        <property type="entry name" value="CALM/Myosin/TropC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048:SF0">
        <property type="entry name" value="CALMODULIN LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048">
        <property type="entry name" value="MYOSIN LIGHT CHAIN 1, 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00036">
        <property type="entry name" value="EF-hand_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="8"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="45"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0013858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="97" mass="10914" checksum="A7C0BD9B47BB4D04" modified="2023-09-13" version="1">MRSLGQNLTEAELQEMIGQIDVDGNGIIDFSEFLTMMSQKMGGTDTEEEIREAFKSFDKDGNGYISPDELRQVMTSLGEQLTDIEIEEMIREADENG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVF8</accession>
    <name>A0A9P6MVF8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_010032</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000657">
        <property type="protein sequence ID" value="KAG0015129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVF8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050562">
        <property type="entry name" value="FAD_mOase_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356:SF2">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356">
        <property type="entry name" value="FAD-DEPENDENT MONOOXYGENASE ASQG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="1"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="239"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0015129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="403" mass="45767" checksum="0F0842DD4F0D9DC5" modified="2023-09-13" version="1">MPVFEQLGLFDELMSISLPCTGINMLDPEFNFMTGLDYGQHKEKTGYDMVMFPRPKLHRLLQSHVPEEKIVYSKKVLSLEQNEHGVMLRMSDGSTIHGDIAVGADGTYSGVRQGLYKSLEKKDLLPASDKEDLTMGHLCMVGTTDPVDPEKYPCVNNEKALFQRVIGRGDSYSWHTVNMRDHRICWGIIFQIDSTVASRDAMFRNSDWGSEGDEGIMYGAFDKPTPIGGTVRDLVDATPKEEVSKVFLEEKLFETWYYGRTVLIGDACHKFLPSAGQGAVNAMQDAVILANCIYEMGEATPENITAAFKEYYDERFEPVRKMMAKSKFMALIMYGTTWKERLIRYIMFNWIPTSIKMKQFFKDAAYRPQASFLEYVENRGTGEVLPQKPSKRYAQEKAAAAEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWE6</accession>
    <name>A0A9P6MWE6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">C-type lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_009408</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000560">
        <property type="protein sequence ID" value="KAG0016148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWE6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="entry name" value="Mannose-Binding Protein A, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051008">
        <property type="entry name" value="Telomere_Capping_Maintenance"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35518:SF2">
        <property type="entry name" value="MAINTENANCE OF TELOMERE CAPPING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35518">
        <property type="entry name" value="MAINTENANCE OF TELOMOERE CAPPING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="320"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="327"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="361"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0016148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="488" mass="54521" checksum="82D5000C44CFFA0B" modified="2023-09-13" version="1">MDRADLESSWWKDGPVGLDYYNTTTDPITGIVSAPTGWPTSLYLTDVIKRRIVVGFGSNNLQANTTYNVTDDFTTLYAPGILGPSKTNSSLLQISSSFDSQDCDNLMPGIMMVPTGSEGTVNQIESQADGNETAYTEVTWAFSSMSDSDSSPWTYSSGQTATTCGYSALVKSRTPVLSFSEQTAMTIWSWDLDQPPANQTFSPDRRCGVMQSNGRWAAQDCNRRLPVACRKTNTSGEWIINDRTANYRDVTCPVGYNFDLPRTAHENELLYTALLNYWNATVPSAFASFLEYQGWRAQNPIQLIRRSVLNVEDSDIMLQKRYRRDEGDEDEREENGIDDDGDYGSADSGNEGSKNQKRRPPSSSSLPNLKPRNLRYRISEREGAMLKSSQETMQLLATIPGLPNDGMIWIDISSWQTAGCWVPGGPHGICPYREPDNTVAIQDIIRVSTIGIFLYLNCRRNVRIRKSNKRRAAVRNKIMLTEVETVPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWJ0</accession>
    <name>A0A9P6MWJ0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphoenolpyruvate carboxykinase (ATP)</fullName>
            <ecNumber evidence="3">4.1.1.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">PCK1_4</name>
        <name evidence="11" type="ORF">BGZ80_009248</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>oxaloacetate + ATP = phosphoenolpyruvate + ADP + CO2</text>
            <dbReference type="Rhea" id="RHEA:18617"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.1.1.49"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.49" evidence="3"/>
    <dbReference type="EMBL" id="JAAAID010000537">
        <property type="protein sequence ID" value="KAG0016394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWJ0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004612">
        <property type="term" value="F:phosphoenolpyruvate carboxykinase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00484">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.8.10:FF:000001">
        <property type="entry name" value="Phosphoenolpyruvate carboxykinase (ATP)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.449.10:FF:000002">
        <property type="entry name" value="Phosphoenolpyruvate carboxykinase [ATP]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.228.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.449.10">
        <property type="entry name" value="Phosphoenolpyruvate Carboxykinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.8.10">
        <property type="entry name" value="Phosphoenolpyruvate Carboxykinase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00453">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001272">
        <property type="entry name" value="PEP_carboxykinase_ATP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013035">
        <property type="entry name" value="PEP_carboxykinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008210">
        <property type="entry name" value="PEP_carboxykinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015994">
        <property type="entry name" value="PEPCK_ATP_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00224">
        <property type="entry name" value="pckA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006820">
        <property type="entry name" value="PRK09344.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006821">
        <property type="entry name" value="PRK09344.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30031:SF0">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYKINASE (ATP)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30031">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYKINASE ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01293">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006294">
        <property type="entry name" value="PEP_crbxkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68923">
        <property type="entry name" value="PEP carboxykinase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53795">
        <property type="entry name" value="PEP carboxykinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00532">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="5" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="11" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0016394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="548" mass="60355" checksum="0E93B5E50A4EB494" modified="2023-09-13" version="1">MAPHKTRSPAASIHKHDAELDASVGKDGIDYTRVNLLRNTSVAKLYEDALRYEPGTSISSAGALVTSSGKKTGRSPRDKRIVDEETTSEDIWWGPVNTKLSEHAFLINHERAVDYLNTRERLYVFDGFAGWDPKYRLKIRVVCARAYHSLFMHNMLIRPTEEELKNYGEPDFTILNAGAFPANRYTTGMTSNTSVSINFKLRQMVILGTEYAGEMKKGVFTIMHYLMPKAGVLSLHSSANQGPNGDTSLFFGLSGTGKTTLSADPARALIGDDEHVWTDTGVFNIEGGCYAKCIDLSAEKEPEIFGAIRFGSVLENVVFDEDTRVVDYSDKSLTENTRCAYPIEYIPNALLPCIGNHPKNIIMLTCDAFGVLPPVSKLTSSQAMYHFISGYTAKIAGTEEGVTEPEATFSACFGQPFLVLHPTQYATMLAQKIHEHTADVWLINTGWNGGVYGTGKRIALKYSRAIIDAIHNGELKKAQYETYPIFGLEIPKAVTGVPAEVLNPAVAWQGTKEEYNATVTKLANLFNENFAKYSDQATADVIAVGPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWT3</accession>
    <name>A0A9P6MWT3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_008956</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000505">
        <property type="protein sequence ID" value="KAG0016755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWT3"/>
    <dbReference type="OrthoDB" id="2448842at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="817"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="440"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="588"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="109"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="234"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="589"/>
            <end position="601"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0016755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="844" mass="93646" checksum="BEEF4A83B4736635" modified="2023-09-13" version="1">MDSSDSSDRTNTLLHDSFIPLRFPNTNSSDAALIVSEQESKDFRSPAKVERCIIQVEDEVPIFAQDQQSADLHHTTVLVSSTFRNSDASTSASVKLKSPLPGPPTYNDLLSPQSSSAMSATSLSNVPTVPEPATTGSQDENEVLTSSTDPPSQTRTVSNSDHLSVSQLAHPLTSSSIPAPVYRHLPLDDDELPGYIPVAENCLTFKLLASQSTTYTVIPSQGPSEFREQGPPLRNQNINNQGTSSRTADRGIPGSDTTQHPDIQEVVHERNSDVLAAHNPHQTGAWTLEYWVNDTIAYLCYLMDPYFPINTDLPQSHSIEQIQMNLTPGRRVEDVELRTFRGSHVTREGRNEVQPQNEHRMEGVHVRHVRGRPPPLNRTRNVTLRQYRPDGATLHISAAEERPATERIDATATLPPISEASSSLPLTSLVPAAPALTTASAGASSTESPEIEADISTVTSSEERHREDLISPQRAAPVSTLPSIQHVQINDGYQGEEADAILAHAVNIQDSHNNTEENMGYSGEFNNALAPTFFKSPTFAFVSAEDPQTWIWWSAHHESNLQKCRMEHQTDVVVMWWRRRTDFYSKVNKEKRKRDKTTRKQMKAESGERGGLKALWHRLLSLQSSESHHQDMEIFMRVRGLHYAWREEDYGSRQSPTMSPLHQHQNPRTTVHDGAAPSYDHWKAVPRIFTLIRDDSFVMGQQLKGDTVAEVWIEGEAGPSISSTSTETALDNHPHSHNSRAFASRLRSSSLAGISVHSSETQLSSSFPAALRKRRCVIRVAQGLHTEVETFALSTGPRLIELYDLYTEQSVPGPSRFSFFSAVGAFAILFIVAFLGTILAKNHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWX8</accession>
    <name>A0A9P6MWX8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008774</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000489">
        <property type="protein sequence ID" value="KAG0016914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWX8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="244"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="183"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0016914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="292" mass="30059" checksum="0E986BA6DF8429CB" modified="2023-09-13" version="1" fragment="single">MSMQSQMRMQMQQQRQQQQLLNQQYPQPLGFSQPPIQNSVTFSPQTYQPSTHLYQTFQQQPGQSVGGGSVGGVNGNNPILTTSNPQGITNLSYVGNGLNPQPPPSLSKKDIWAAQQANLQAQLNKNNLNAGMIAEGGKDRDVASTKKLQQMFQYQQQQTNFSTPDSSAGSAGSTPSRTIVSEANAPATPTGGGSASTSTPSSAIGSSVSASGATSNVTVSVAAPLGSIASSIPSIPPIPFVSTTTNNSPMAAVNGPASPATVSTNSSGSWTGMSSVTSSAFNTPTLGLQPPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWY5</accession>
    <name>A0A9P6MWY5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_008931</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000501">
        <property type="protein sequence ID" value="KAG0016804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWY5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052981">
        <property type="entry name" value="Ingression_C2_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47052">
        <property type="entry name" value="CONSERVED SERINE PROLINE-RICH PROTEIN (AFU_ORTHOLOGUE AFUA_2G01790)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47052:SF3">
        <property type="entry name" value="INGRESSION PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2" evidence="2">
        <location>
            <begin position="14"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="338"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="364"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="576"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="586"/>
            <end position="601"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0016804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="607" mass="63670" checksum="03AB552B968B9E16" modified="2023-09-13" version="1">MHRLLNVAGRHPTGMNKPLPEPLVDPDEGKTPIGELVIVPIQGKDLPNRERFGKQDPFILFKLGNVSKRTTTDIRGGQRPQWKDDQISILMYKSDAKDATSLYVTCLDEDQKKDDLIGDCVINLAKVLEIGELDGMDPKHPTNRMNRVPPVPAHSGSGAPLRRPINKKPKAEGGKPEVEEEHVDEGPVYKPPVVSEAVTPPTPATPQVPVVPGAAGYPYGTISGGAPRPLSPSGASTPYGGHHTPQVPPANPYSTPAVPPANPYATPAVPPANPYATPAVPPTNIYGTVNGGYPGYPTAGPFPDPSLTADPSKRASFTGQPPVQPGGFLSGYPQGAAPGVGGYPPQAGAGGPAGGPAGGPPAGYPFAASNAYPPNSNNSSSGGAPGFPQGPGTNNGGYPNTFPGNNNNNSNNNGPYSNNGGINNHSNGNLNNFNNNNNNFNNNNNNFNNNNNFNKNNNNFNNNNNNNFNNGGNNNFNNGNSSNNNSFNNGGPNNFNNNNSFNNNNGGNSFNSNNSGPNNFSNGGNNFNNNNGGGNFNNNNNNRSSFNNNNNNNNNFNNGQNQSFNNGNNNGGGYGTPKKTNTITPTPVPITPVVQPRPGPMYDPSEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MX32</accession>
    <name>A0A9P6MX32_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rab-GAP TBC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_009774</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000614">
        <property type="protein sequence ID" value="KAG0015580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MX32"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050302">
        <property type="entry name" value="Rab_GAP_TBC_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219:SF9">
        <property type="entry name" value="GTPASE ACTIVATING PROTEIN AND CENTROSOME-ASSOCIATED, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219">
        <property type="entry name" value="RAB GTPASE-ACTIVATING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="2">
        <location>
            <begin position="384"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="26"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="152"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="186"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="223"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0015580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="620" mass="68840" checksum="D8AF2652211BBFB2" modified="2023-09-13" version="1">MTTSSASEPDTGNALSTGPSMDRKASSPSISTSFTSPEISSTDTSPTLVRLHEKEFVTAATKVENDFEDTIDSRDGAELEQGSTRTTIRSSMESTPTSLLSESPPTSISVATQDSSDASSIGQQNATSFVPNGTHDGHKATANRSRRASHVQQQQRTQQKQYETEPKEMGISVLVGCDAEGSDNNTITTPTSASPTSSSLEHSSILYADMDMFVTSSTRNAKSPPTSTTSSISTGRRKIAESSMILSAGTLPAATSIAAGGSLSPAWSMTSIPRDISAAYNQNLEQREPSADEKLYGLVDRYGFLVEEGRTPISDRSTIQATLTSSQRSVRPINEPKTQAKTVEKEQERSLKWAKMAKQYTSEAKETEYSFPNNSKFIKRVYKGIPDCWRAAAWSFIVTKRSANFEPNIRQIYQDMLSVSSSEEEQIDLDIPRTMHGHIMFRTRYGPGQCALFKKTFVLLTQLFERYNINNLVVPGFPALFEAFYIQEELTKIYAPRVFEALETMGIATASYASRWYITLYSAGVVPYRTLLRIWDIFLLEGFDWLYFMALALLKYHESSLTQNNFEQTMEMLNAKMDIQDDDRLVRIARKLFKQALKTGIVAKLKEQYAANQRLATTAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXK9</accession>
    <name>A0A9P6MXK9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ribosylnicotinamide kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">NRK1</name>
        <name evidence="2" type="ORF">BGZ80_008183</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000437">
        <property type="protein sequence ID" value="KAG0017529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXK9"/>
    <dbReference type="OrthoDB" id="10041966at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02024">
        <property type="entry name" value="NRK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006083">
        <property type="entry name" value="PRK/URK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10285">
        <property type="entry name" value="URIDINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00485">
        <property type="entry name" value="PRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphoribulokinase/uridine kinase" evidence="1">
        <location>
            <begin position="23"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0017529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="276" mass="31039" checksum="9DBE5303C72E8BF4" modified="2023-09-13" version="1">MLSHGDANETDNLSHIHPNVITIGLSGPSSGGKTTTSRYLRSILPNSTIIHQDDFYLPEDQLPIDPKTGHANWDCPEAIDFDSLISTLTFVKEHGKFPDGFDSLEDKNPVGSETSSDPIPDQVLEGWREQIMDQIPQDKRPHTKFVIVDGFILYVNERLRKTLDVKFYLSASYQILKERRESRKGYATLEGYWVDPPGYFDDIVWPNYLAYNDPFVKLMEAVEAGQVTGVYDAKSESSRPDPMTQEVDLVSSNSSSIHSMVETVSDLLAKRLAELP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYA9</accession>
    <name>A0A9P6MYA9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008875</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000498">
        <property type="protein sequence ID" value="KAG0016838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYA9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0016838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="87" mass="9812" checksum="89E81A2CE26C059F" modified="2023-09-13" version="1">MRCNDENEDSVEANTNEARLELALQHEDWAEADWKQVIWSGESTINRISSDGMRYVWAQADNEPKVKAADIDPELAGPTVRHGGESR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYL4</accession>
    <name>A0A9P6MYL4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_008002</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000421">
        <property type="protein sequence ID" value="KAG0017709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYL4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="84"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="238"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="473"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="549"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="756"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="123"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="514"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="549"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="577"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="595"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="652"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="768"/>
            <end position="779"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0017709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="779" mass="84220" checksum="A0CE0117A2FC9791" modified="2023-09-13" version="1">MDWSPSVSVDDSEAFATTSDSNANNNSNNNGLIDIYCSQQRREYIDPHLADHIADLCTLKLQQSSSGRHQSLLRHKDPANHLRLCNYVSFFYLIATIHSMLHRIRMQTFMRPVMTGYLHHHNQFQQPQEQQQQEQQQQEQQQQSMVFEQEVSAPQPQGYNWGQEVSLNSTALSFDMLLGMGSSQSLVSDVSTLPGTSSSSTMDDTEQVILGFGQPQQHHPLSSIPLVSFTGDYSAVSSGSSDDSFQHQTTSISLSSIPPSPAPLSQQQSLAVVAALPHQTYYELLMAANPNEPLSQLLSTSATTMTSPSFSVTSSSTASALAQGSQPSYGVLDTPIQASLTLSVSSTEGSSMGVRLSSVGSNFAMPNFPGGSEPTTHSPQQTIPLTTKEIMDALSGQFPIQPMTPSASELPVSDVVSEPILSDALAMGKSAVPSIASVLSPTYATASMQGSESIRTDFPLAEPSEDVNANAHDQENEPAAIGEPSINVSTAESLQKQDESWDSDSNMQSPPPTHHHEGDDKDSSVTINNTVEHQDGNQEVNMDLDLTDISLLSPPSSPSKSNTRSPKRTKSSSTSRRSSRTQTRRSRAKHEAESFTVSHDTRNSTPGDAPEDAIRTPKRRRVSDDDTLSCSSPESLPPSPRTPPATLENHCTVHQRSIQNHEVSSDQMAEQQGEAFELDSKRSKEECEGDCTVIEDPNFAAMADSKNPGSQTSSEAQENAGILSPSLLTRYPTRQSTRILRRTSGRLQSVASCGANTHHRHVNGGEPALLTTTSKATAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZ23</accession>
    <name>A0A9P6MZ23_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006235</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000307">
        <property type="protein sequence ID" value="KAG0019155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZ23"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="248"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="282"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0019155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="307" mass="34364" checksum="CF61FE00ED8E600E" modified="2023-09-13" version="1">MPGRLCGLDVHFVLVYDAHYLVVPIPVHICGYPDPQHLVERTEDLGVFKERSRISAKTNRRADLPWVFVSGALGFYLVGIIYATPASFSTHNVFSSKKRHSQGADNNVNNFHDASRFSSLMEPKRVYLPSPMVLNFTLLGLTFLPLVINQILASFGGVAFDRGDMDMYNIMISAMYGVWTFVVAIIFGLYIFFGKQLLTIISSNMASINDNVGRVSSRIGADSEYAERDDSERQLNTLKSTYQRMKAILILCGSLSAIMGLMMLSFAIFRRQILNDETTSEVFSLIWIHGASVALGCSLIFILFRKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZ57</accession>
    <name>A0A9P6MZ57_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HCP-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_007374</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000376">
        <property type="protein sequence ID" value="KAG0018275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZ57"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="97"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="33"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="97"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="134"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="144"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0018275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="508" mass="56667" checksum="2F5C09CA3B63EC78" modified="2023-09-13" version="1">MANTQHEENQLILGPDDKDNVTGVTTPLPWSESTKEQDGDSAAERHPHHRNSIGLPHINIVLPNIDRWLTPAIDAYHIGVGFEAQDVESSRITIPFKNQSGRPLTDTAPSTYHGIPSTSAINSIQLERHDETPSSKPKSTETTLQSDSNSENMNGDLYSRAQAAFERYNGTSPTNRDMGVECLKVDMEVEYGFGVSYLDAEVPDYLAAFECFLEAAKKGHVDAHHRLGCMDGLGIARNYTKATACYRKAASQGYASAQSSLGSMYEKGYGVIRSYYKAVDWYLKAANQGDAAGQYNLGYMYRLGRGVGKDYFKAVEWYQKAADQGYAKAQYRLGHRYEIGKGIDQDLLMAVELYQKAAIQGCAGAQFNLGRMYHRGRSVTQDYLKAEEWYQKAADQGYAHAQRNLGILYQDGCGVTQDHLKAVGWYRKAAIQGDNTSMYNLAHMYRNGLGVKQDYNKAVVWYQKAASRGFVKAQHDLGVMYYNGEGVPKDISRATELWEMALRYSPPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZK5</accession>
    <name>A0A9P6MZK5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_005716</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000281">
        <property type="protein sequence ID" value="KAG0019508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZK5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31437:SF1">
        <property type="entry name" value="PROTEIN SREK1IP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31437">
        <property type="entry name" value="SREK1IP1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13917">
        <property type="entry name" value="zf-CCHC_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="6">
        <location>
            <begin position="26"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="46"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0019508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="91" mass="9806" checksum="1348321E8FDEF82C" modified="2023-09-13" version="1" fragment="single">MSDFQRGLQAFERLVKSDEGVRTGSCRKCGGSGHLTFECRNFVKLDGPSSKPKTNSRFGFLKKQLGTTPSPPSGSGTETPSVDADSNKHMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZM9</accession>
    <name>A0A9P6MZM9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Serine/threonine-protein phosphatase 2A activator</fullName>
            <ecNumber evidence="6">5.2.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Phosphotyrosyl phosphatase activator</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">RRD2</name>
        <name evidence="8" type="ORF">BGZ80_006733</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the PTPA-type PPIase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="6"/>
    <dbReference type="EMBL" id="JAAAID010000334">
        <property type="protein sequence ID" value="KAG0018786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZM9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000159">
        <property type="term" value="C:protein phosphatase type 2A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008160">
        <property type="term" value="F:protein tyrosine phosphatase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04087">
        <property type="entry name" value="PTPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1150:FF:000002">
        <property type="entry name" value="Serine/threonine-protein phosphatase 2A activator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004327">
        <property type="entry name" value="Phstyr_phstse_ac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043170">
        <property type="entry name" value="PTPA_C_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037218">
        <property type="entry name" value="PTPA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10012">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE 2A REGULATORY SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10012:SF5">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE 2A ACTIVATOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03095">
        <property type="entry name" value="PTPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140984">
        <property type="entry name" value="PTPA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0697">Rotamase</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="147"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="16"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="175"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="185"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="213"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0018786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="620" mass="68683" checksum="3D02B6B9D0FC44D1" modified="2023-09-13" version="1">MAESDVKRSFAEEDVSSTSFLTPATNPNARPSGRHSIDYSEKAPQVMEWTSTIAKENIRILPISTTDIGQGNEDDQAALTPTSASFRIDHDLEELQKLTPTLVEVPAADIPDIQNLNLASFSSQNPSYLSSKPYSISGHYAKGLEVPSVPSPPSSVIAEPPSPTLSHASLKLGGTYSSTSSNAGEEQDQYQDMEQDSIQVSQSSEHDSFVGINTPSTPTSSSSNNNDNNNNNNNDDDADNNNNNTVESQPIDKNAFVVPRKEILTKEDLELFHASTTYANLFDFLDALNESVVGVVSTADCYESEVVKGMLETLDLVNDITEEYPPETGHESRFGNPAFRKFYDQVGLSAPAWMEKLVQPKEAIPEVTKYFVECWGNRKRIDYGTGHEASFLAWLYCFHKLGLIKQEDYKAVVIKVFFKYIEVMRNLQFAYWLEPAGSHGVWGLDDYHFLPFLFGAAQLRGHKYIRPKSIHDNDIVSEFSKDYMYLSCVKFINSVKSASLRWHSPMLDDISAVKTWDKVNSGMIKMYKAEVFGKLPIMQHFLFGSLLPFKGQSDTRILDEDEEEAGVEGHTHVHAFGQEFPTCCGMKIPSAIAAAAAANASGERTIPGVPSSGARRLPFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZN1</accession>
    <name>A0A9P6MZN1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_007046</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the IFI6/IFI27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000354">
        <property type="protein sequence ID" value="KAG0018538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZN1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009311">
        <property type="entry name" value="IFI6/IFI27-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038213">
        <property type="entry name" value="IFI6/IFI27-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019956">
        <property type="entry name" value="Ubiquitin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050158">
        <property type="entry name" value="Ubiquitin_ubiquitin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10666">
        <property type="entry name" value="UBIQUITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06140">
        <property type="entry name" value="Ifi-6-16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00348">
        <property type="entry name" value="UBIQUITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="6">
        <location>
            <begin position="118"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0018538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="190" mass="18889" checksum="71F63A152C2C961A" modified="2023-09-13" version="1">MPSKKEIDTTISAATAAVAAASSSPLSSAIAAACAAPSLFTSTVAAVGFGTSGIVAGSPAAAFMASYGGLVSSGSLCASLQSIGAVGLGPVGFVVTGAVGAAVSIGVSAYSARKNSSVLIVVQSKDGLSLAVEVLSLDTIDDVKSKIEIKSGIPKDKQTLHFSGIPLEDHRRVQDYGIKDQSVIVLVCYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0A0</accession>
    <name>A0A9P6N0A0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000284">
        <property type="protein sequence ID" value="KAG0019463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0A0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="105"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0019463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="171" mass="17610" checksum="C3FBD271E92E23AB" modified="2023-09-13" version="1" fragment="single">MSRKPDRGVKPAQKVLDPEARKRQLRHHLDSLERDNFVALNEYEAIIATAAAAATAQGLLPPLSPAVGSIVGGVVGTVGPGAVNNLGAKPAGALSGSRSKKTQLGINQSGNSAISSNSGSPSGAGSNSNYALLGHRKPVLPRKPLNQLLEESRSLNNQSTVQTYVTAAMGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0C8</accession>
    <name>A0A9P6N0C8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">proline--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Prolyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_006416</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>tRNA(Pro) + L-proline + ATP = L-prolyl-tRNA(Pro) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:14305"/>
            <dbReference type="Rhea" id="RHEA-COMP:9700"/>
            <dbReference type="Rhea" id="RHEA-COMP:9702"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78532"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.15"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.15" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010000317">
        <property type="protein sequence ID" value="KAG0019015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0C8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017101">
        <property type="term" value="C:aminoacyl-tRNA synthetase multienzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004827">
        <property type="term" value="F:proline-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006433">
        <property type="term" value="P:prolyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00862">
        <property type="entry name" value="ProRS_anticodon_zinc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.110.30:FF:000001">
        <property type="entry name" value="Bifunctional glutamate/proline--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.800:FF:000005">
        <property type="entry name" value="bifunctional glutamate/proline--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="entry name" value="Anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.30">
        <property type="entry name" value="C-terminal domain of ProRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004499">
        <property type="entry name" value="Pro-tRNA-ligase_IIa_arc-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016061">
        <property type="entry name" value="Pro-tRNA_ligase_II_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017449">
        <property type="entry name" value="Pro-tRNA_synth_II"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43382:SF2">
        <property type="entry name" value="BIFUNCTIONAL GLUTAMATE_PROLINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43382">
        <property type="entry name" value="PROLYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09180">
        <property type="entry name" value="ProRS-C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00946">
        <property type="entry name" value="ProRS-C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64586">
        <property type="entry name" value="C-terminal domain of ProRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proline-tRNA ligase class II C-terminal" evidence="10">
        <location>
            <begin position="229"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0019015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="319" mass="34983" checksum="695E7659E1A163E4" modified="2023-09-13" version="1" fragment="single">GVKSENEKFAGGLYTTTIEGYIPTTGRGIQAATSHCLGQNFAKMFGISFEDPQGPLPNGEARPPLHAWQNSWGLTTRSLGVMIMIHGDDKGLVLPPRVASVQVIVIPCGINAKTSDEDKAAVEERVADILKQLKKAGIRAKSDDRTTYTVGYKFNHWELRGVPLRLEVGPKDVSNNQVLAARRDNGEKTTIQHAELVKGVRDLLDTVQSDMFTRAKATRDANVAHIVDWKDFVPALDDKKICLIPWCETPACEDEIKEKSARTNIATAEVQDEKAPSMGAKSLCIPLEQPQDKPIVAGETKCVSCGKDAKRWALFGRSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0F8</accession>
    <name>A0A9P6N0F8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_004077</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000212">
        <property type="protein sequence ID" value="KAG0020516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0F8"/>
    <dbReference type="OrthoDB" id="2372055at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="230"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="260"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="359"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0020516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="420" mass="46526" checksum="A05DE0503F9B3C47" modified="2023-09-13" version="1">MSTFDSEDPFDSGQQWQNVPTHLAWGNLTSATTVTVEEETFIPEAPTTQLVQPSAPVLPHSTDTPTTVTPPPEVETASADITEPARPAHLDDLPPSYEAAIIKDRPQIHDNYDHLRGPASQRGVDIKTRIPLDSTPASHYQSGGSGSGSGGAGSSSRPEGQDGESGARYGSISPPRLHGQVSQGREDDELHSRDVDRLLGPSNDPSHAEYHNHMHEEPETGWSIVGVGRVWVGLAYLLVILFPWALFCFVWTIVTGLIAAITMIVPPIGYLFVIATITSWRALARVDIVVSRSLVTWYVREKHPHVLAKIFVRLPESHPAPLPPGTRRSRRKNLWQRGADHLKATIGNKHSFTAMSYFLIWKAVFALLAFPIVLVFSVLTIPFMVCLLPSLLIFCRMLINWQFRWAVFWLAEKKQPIALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1Q7</accession>
    <name>A0A9P6N1Q7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Cation-transporting ATPase</fullName>
            <ecNumber evidence="13">7.2.2.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BGZ80_003984</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Membrane</location>
            <topology evidence="1 13">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.-" evidence="13"/>
    <dbReference type="EMBL" id="JAAAID010000209">
        <property type="protein sequence ID" value="KAG0020560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="48943at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015662">
        <property type="term" value="F:P-type ion transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07542">
        <property type="entry name" value="P-type_ATPase_cation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000023">
        <property type="entry name" value="Cation-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000057">
        <property type="entry name" value="Cation-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000057">
        <property type="entry name" value="Cation-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000068">
        <property type="entry name" value="Cation-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006544">
        <property type="entry name" value="P-type_TPase_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047819">
        <property type="entry name" value="P5A-ATPase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047821">
        <property type="entry name" value="P5B-type_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01657">
        <property type="entry name" value="P-ATPase-V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45630:SF8">
        <property type="entry name" value="CATION-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45630">
        <property type="entry name" value="CATION-TRANSPORTING ATPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12409">
        <property type="entry name" value="P5-ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01229">
        <property type="entry name" value="COF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 13" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="195"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="382"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="579"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="615"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1150"/>
            <end position="1168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1174"/>
            <end position="1193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1214"/>
            <end position="1236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1261"/>
            <end position="1280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1292"/>
            <end position="1310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1330"/>
            <end position="1351"/>
        </location>
    </feature>
    <feature type="domain" description="P5B-type ATPase N-terminal" evidence="16">
        <location>
            <begin position="178"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="15">
        <location>
            <begin position="421"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="517"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="19"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="80"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="101"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="125"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU362082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF12409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0020560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1452" mass="162515" checksum="E403DDDC04F53DB4" modified="2023-09-13" version="1">MKNPGLLHSSSHDRRHNIHNINDSNNTDSDNSNSSSGNTGNNAGRTTESITARSNAMEYLNSTDPGRRRSSTLSLLHGDSASNLNSSSNGKTEDKFDFDNSSPSGHFSHFPSQTLSQRFNHESDSENDYDEDHDDSDRTEGDMSPYATKAKPKSVAKRPPAIDHRHDRCKQRVYLEEEDVELIFTGYRFRQSRLYLYYLFCLLSFGIVFLLGRWMPQQYINFVAEKCEMGKAECIVVENEWGQISMEPIFTKYYGGPIDSVFSPEQMEKSSNDDDVSLNETVTTGMLHDMRYFDYQYIRFIYNPTVQLFMENSHWKDPDWSSAANCERGIGRETHQERTMVFGQNIIEVQEKTTGQLLVQEILHPFYIFQVFSMALWFSDDYYYYAACIFIISTVSVVTELVETKRTMRRMRNMSRFTCNTKVFRSGRWRYIGSDELVPGDVFEVTDSDLTVFPCDAVLLTGDCIVNESMLTGESVPVSKIPITAAALQHLDLSLSNIPSEIARHFLFSGTKIVRARPGASSQQNQANAEDDEFGTSSPPRGLAMVVRIGFNTTKGTLIRSMLFPKPNDFQFYRDSFRFIGILAMIACGGFLISTVNFVRMGVPFRNMIVKALDLITIVVPPALPATMSIGTSFAIARLKRSNIFCISPTRVNIGGKINCMCFDKTGTLTEDGLDVLGVQCTDSDTKKFGEMLSTVEEMQNAPKSLQDKTTPMLFAMTTCHSVKSVNGELIGDPLDLKMFDFTQWVLDEGGLGTRIANISESSQKGGKANMGGIVSTVVRPPGGKQFNLEDMIANHGSREPSESASLGTHMNNFAFQNEFLELGIIRCFEFISSLRRMSVIVKRLHSPGMDVFVKGAPEVMTDICLKETLPLDYSERLAYYTHHGYRVIACAYKSMPTLNFLRAQRAKREQVESDLVFLGFIVFENKLKPTTASIVATLSNARIRQVMCTGDNVLTAISVSKECGLINKAREVYTPRFVSGDSMTENSEIVWENTDDERMTLDPITLKPSVSWSDDSSHGPEFPRYDHMMNDYVLAVTGDCFRWMVDYAPTSTLNRMLVKGQIFARMSPDEKHELVEHLQVIGYCVGFCGDGANDCGALKSADVGISLSEAEASVAAPFTSRSSDIACVVKVIQEGRAALVTSFSCFKYMALYSIIQFTTVSFLYAFASNLGDFQFLYIDLILILPIAVFMGRTEAYPLLNPKRPTANLVSKKVLTSLIGQIMIQSLFQAMLFVIIRRQPWYTPPVYDSEDTNIECYENTVLFLLSCFQYLLVAIVFSVGPPFRKPMSSNRPFVLITIALVLTSAVMVLFPTKWLSEVMELVDIPFTFRVSIMIIAGVNLALSLICEHYVFPIIARRIGDWLNERKAQRGMKHGEQVHAPPPQQSIGYGSQAITTPVAMHDDSRDTEVGGGGYSVHAPAQIQSNTGVEAKRATGKKSSVKIYKIVEDEMMGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2Q7</accession>
    <name>A0A9P6N2Q7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">glutamate synthase (ferredoxin)</fullName>
            <ecNumber evidence="16">1.4.7.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">GLT1_2</name>
        <name evidence="19" type="ORF">BGZ80_010507</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="15">Amino-acid biosynthesis; L-glutamate biosynthesis via GLT pathway; L-glutamate from 2-oxoglutarate and L-glutamine (ferredoxin route): step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Energy metabolism; nitrogen metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the glutamate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.7.1" evidence="16"/>
    <dbReference type="EMBL" id="JAAAID010000074">
        <property type="protein sequence ID" value="KAG0023046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N2Q7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051538">
        <property type="term" value="F:3 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016041">
        <property type="term" value="F:glutamate synthase (ferredoxin) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016040">
        <property type="term" value="F:glutamate synthase (NADH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019676">
        <property type="term" value="P:ammonia assimilation cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006537">
        <property type="term" value="P:glutamate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00713">
        <property type="entry name" value="GltS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000031">
        <property type="entry name" value="Glutamate synthase 1 [NADH]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000001">
        <property type="entry name" value="Glutamate synthase, large subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050711">
        <property type="entry name" value="ET-N_metabolism_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006982">
        <property type="entry name" value="Glu_synth_centr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002932">
        <property type="entry name" value="Glu_synthdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11938">
        <property type="entry name" value="FAD NADPH DEHYDROGENASE/OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11938:SF133">
        <property type="entry name" value="GLUTAMATE SYNTHASE (NADH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00310">
        <property type="entry name" value="GATase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04898">
        <property type="entry name" value="Glu_syn_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01645">
        <property type="entry name" value="Glu_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0003">3Fe-4S</keyword>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0288">FMN</keyword>
    <keyword evidence="13" id="KW-0314">Glutamate biosynthesis</keyword>
    <keyword evidence="9" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="18">
        <location>
            <begin position="36"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="881"/>
            <end position="909"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="894"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="19">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00037928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00039085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAG0023046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="949" mass="105078" checksum="53E2609A48443CB9" modified="2023-09-13" version="1" fragment="single">MESFMNKNNIESNSSWAGALPVAQGLYNPENEKDSCGVGFIANIKGEHSHRILKDASNILCNMTHRGATSADPRDGDGAGVMTGMPHSFFVEEAGRLNIKLPAQGEYAVGNVFLRPDEPHVYEQKSTFESIAQQNGLKVLGWRSVPVDNSILGPSSKSKEPSIQQPFVILDPSVHATFDNKRFQRQLYILRKEATHAITLKNWFYICSLSNQNIVYKGQLSPVQVYDYFYDLQNHKYLTHFALVHSRFSTNTFPSWDRAQPMRWAAHNGEINTLRGNKNWMRAREGVMSSDYFGSDIQKLFPIIEDGGSDSSAFDNVLELLVVNGVLSLPEAIMMMLPEAWQSNDNMEPEKKAWYEWAACLMEPYDGPALMTFSDGRYCGASLDRNGLRPCRFYKTTDGLMICASEVGTMNIAPERILEKGRLQPGKMLLVDTLEGRVVDDRELKLSIAARHNFRQWVDEQMLSLEDAVANAPKFDAVASVDDVPLTQDPRLSAFKFTIEQLNLLLMPMTTDGKEALGSMGNDAPLACLATEPQIIYDYFRQLFAQVTNPPIDPIREEIVMSLECYVGPEGNLLEIDQSQCHKLKLTTPILSLTEMEAIKNFDITRADWKTRVIDITFPKSEGPAGYVPCLERVCDEVSAAIQDGVKIVVLSDRGVSAERVALSALIATGGVHHYLVNEKKRSRVAIGVETAEAREVHHACVLIGYGADMICPYLAQEAIVKLHRENSLRSEHGPEKLIKNFIKATSNGILKVMSKMGISTLQSYKGAQIFEALGLDEPVIARSFAGTASRIKGVGFELLALDAFALHERAWPSRDTVAIEGIPESGDYHWRNGAIPHINDPDVDEVEPWTAICKRFCTGAMSYGSISMEAHSTLSIAMNRIGGKSNSGEGGEDPERSNPRENGDSLRSAIKQIASGRFGVTSYYLSDAEEIQIKMAQGAKPGEGGELP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2S3</accession>
    <name>A0A9P6N2S3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DNA polymerase epsilon catalytic subunit A</fullName>
            <ecNumber evidence="5">2.7.7.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="22">DNA polymerase II subunit A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="26" type="primary">POL2</name>
        <name evidence="26" type="ORF">BGZ80_002210</name>
    </gene>
    <organism evidence="26 27">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="26" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="26">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="23">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DNA polymerase type-B family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TUBGCP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="26">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="5"/>
    <dbReference type="EMBL" id="JAAAID010000154">
        <property type="protein sequence ID" value="KAG0021530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008622">
        <property type="term" value="C:epsilon DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000930">
        <property type="term" value="C:gamma-tubulin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005816">
        <property type="term" value="C:spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043015">
        <property type="term" value="F:gamma-tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008310">
        <property type="term" value="F:single-stranded DNA 3'-5' DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006287">
        <property type="term" value="P:base-excision repair, gap-filling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045004">
        <property type="term" value="P:DNA replication proofreading"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006272">
        <property type="term" value="P:leading strand elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007020">
        <property type="term" value="P:microtubule nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006297">
        <property type="term" value="P:nucleotide-excision repair, DNA gap filling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05779">
        <property type="entry name" value="DNA_polB_epsilon_exo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05535">
        <property type="entry name" value="POLBc_epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.132.60:FF:000002">
        <property type="entry name" value="DNA polymerase epsilon catalytic subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000010">
        <property type="entry name" value="DNA polymerase epsilon catalytic subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1600.10:FF:000006">
        <property type="entry name" value="DNA polymerase epsilon catalytic subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.60">
        <property type="entry name" value="DNA polymerase family B, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.342.10">
        <property type="entry name" value="DNA Polymerase, chain B, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1900">
        <property type="entry name" value="Gamma-tubulin complex, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1600.10">
        <property type="entry name" value="Palm domain of DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006172">
        <property type="entry name" value="DNA-dir_DNA_pol_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006133">
        <property type="entry name" value="DNA-dir_DNA_pol_B_exonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042087">
        <property type="entry name" value="DNA_pol_B_thumb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013697">
        <property type="entry name" value="DNA_pol_e_suA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023211">
        <property type="entry name" value="DNA_pol_palm_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040457">
        <property type="entry name" value="GCP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042241">
        <property type="entry name" value="GCP_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041470">
        <property type="entry name" value="GCP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029703">
        <property type="entry name" value="POL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055191">
        <property type="entry name" value="POL2_thumb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054475">
        <property type="entry name" value="Znf-DPOE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10670">
        <property type="entry name" value="DNA POLYMERASE EPSILON CATALYTIC SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10670:SF0">
        <property type="entry name" value="DNA POLYMERASE EPSILON CATALYTIC SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03104">
        <property type="entry name" value="DNA_pol_B_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08490">
        <property type="entry name" value="DUF1744"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04130">
        <property type="entry name" value="GCP_C_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17681">
        <property type="entry name" value="GCP_N_terminal"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22634">
        <property type="entry name" value="POL2_thumb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22912">
        <property type="entry name" value="zf-DPOE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23250">
        <property type="entry name" value="zf_DPOE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01159">
        <property type="entry name" value="DUF1744"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00486">
        <property type="entry name" value="POLBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="20" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="12" id="KW-0235">DNA replication</keyword>
    <keyword evidence="19" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="16" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="17" id="KW-0408">Iron</keyword>
    <keyword evidence="18" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0493">Microtubule</keyword>
    <keyword evidence="10" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="21" id="KW-0539">Nucleus</keyword>
    <keyword evidence="27" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="15" id="KW-0862">Zinc</keyword>
    <keyword evidence="14" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DNA polymerase epsilon catalytic subunit A C-terminal" evidence="25">
        <location>
            <begin position="2634"/>
            <end position="3033"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="24">
        <location>
            <begin position="165"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="24">
        <location>
            <begin position="885"/>
            <end position="1010"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="24">
        <location>
            <begin position="1104"/>
            <end position="1146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="24">
        <location>
            <begin position="2809"/>
            <end position="2828"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="24">
        <location>
            <begin position="3098"/>
            <end position="3120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="24">
        <location>
            <begin position="173"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="24">
        <location>
            <begin position="926"/>
            <end position="945"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="24">
        <location>
            <begin position="956"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="24">
        <location>
            <begin position="993"/>
            <end position="1003"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="24">
        <location>
            <begin position="1112"/>
            <end position="1129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="24">
        <location>
            <begin position="1131"/>
            <end position="1146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00032919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="ARBA" id="ARBA00049244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="SMART" id="SM01159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="EMBL" id="KAG0021530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="3377" mass="384882" checksum="872790BCCFB23E4F" modified="2023-09-13" version="1">MLIPLPQPGTDYFNICSSYVALHLYDVGGMGGVRNKVMDHKAIDRRLNGLAEKVSLHGHESKADALREYLRRLRRLARSLGGGDSVRMTGGSEMDREEAAQNVMSSILLVLLELSESPITLRRGEVLYTIPDRLKESKGKPKSQQQINREIWMNILKEDPFVGDHWQLNTEGDQQDSDGSDFEDMDVNPRAVPNDNEAQLGSEGGTDSTKPVDDGSSPPPGTLELWTGQSRQKLKSVTNLGVFERHQYWRKKAIVSKKHAVASRIEELGLDIQRPSDLNSALQKSSEFVLAQSTPVMDEADIIHEVLLMLQGHSTVIFTFDKEDLTATYSTKVALSHMSQGALEAILQPFLESAGEISKLQMIVDTVCSVPAKVYGKVIQAFASAMNSELLELREFLAVKQKEYQRFRKELPPNSSDRSCRFSTDVLSGLYDNVGKFELSGDSISSTLFLRLLQQSIKPLLLNMECWLSGKPLDSENEFLIQTASNIDLFSSEFWTDGCYIQSEIVERRNDGKNSNMSTAKIFPCFLNERSLNQMVYTGKAIRMVITMPKAENFASTTFARIFGKEDSNRASAVVPPSPSPMDREFPNYSSILAHQYPLSSSSSAAAPLPPLVHSSGTPTFATDYTNAFDIQWMMETELAKSIEEQYQSANSLLKSMLFTQSKLIWHLRGMAEFNFMMQGEVMHLFSTTIFEKCDWKHAQFVRVRVNNQSRKKSDRIHIMGLKVQDLDLIEFEYLLPWPLSGIIYSTENAKRMYTRITCLLFQVKTVKHAIEQATFLKSKPKRSHELGLFWKLRLRFLSTMNDLWSYLMTTVLDTQIKRFQSEIEDQCDLDDIIKLSSRFIRLCYERCFLKERTLPLHRSLITMLNLALKFSALFSTFIHEQERNVQNQQQPANPHEGAGIGSGARSGKMVSETSDYVSKSGRRVSFNNAPGKQQQGITSGSHRVSQGIYGSYNTDSEDETLEDQVRDDEEEEGERDEIFSSGTADKRRKGTRTNSLKDVSTSEGIDGDEDIEMDSSVAIRSHAKKQKIDADLWRGTSRGERWSHEGSYQEQLKAIEQEFNRCREFLAKSLRVVVNSNAVRGYANRNNNGADAADGMGLMGQGEGDSNYLDGRGGASRGGRGRGYGRGGKSYRAPSSQSSTAAGAQQAYVATGDEGTFVEQRFDDVALQDEIDEKLGFYKFQEGPEKLGWLINQHATLVRDEDWPTGRAAIDYYFIQDDGEMFKTTVKYSPYFYIASKVGHETDVEEYIRRKFENLVEKMTRVQKEDLDMPNHLLGNTRTFIKLAFRNVRDLLSVRKVVLPAAKENQSKMSALDTYAEVVSASLDMSLDPEPVSSSTRSAGDGLDYIVDIREYDVPYTIRVAIDKDIRIGLWYNVRVTHSDVEITRQMDRVARADPVVFAFDIETTKLPLKFPDSAIDSVMMISYMIDGQGFLITNREIVSQDIDDFEYTPKPEYEGLFTIFNEPNEQECLRRFFHHVQEVKPTVFVTYNGDFFDWPFVEARAKIHGLDMFHEIGVKKDDEDEYKSNTAVHMDAFRWVKRDSYLPMGSQGLKSVTKEKLGYNPMELDPEDMTRFASERPQTLAQYSVSDAVATYYLYMKYVHPFIFSLCNIIPMNPDEVLRKGSGTLCETLLMVEAYQGNIIMPNKHTESYNKMYDGHLLESETYVGGHVEALQAGVYRSDIPNHFNIVPEAAQQLIDDLDAALRFSIEVEGHLSMDDVENYEEVKAAIAAPLADLRDRPNRTENPSIYHLDVAAMYPNIILTNRLQPDSIIDESTCAACDFNRVGKECDRRMTWSWRGEYFPAKKNEYNMIRNQLESERFPGKKAWDEPRTFHSLSEAEQAALISKRIAEYSRKVYRKTHETKVMEREAIVCQRENPFYVDTVKAFRDRRYEYKGLHKTWKGKVEKAVASGDLVEIENAKKMVVLYDSLQLAHKCILNSFYGYVMRKGARWYSMEMAGIVCLTGARIIQLARKLVEQMGRPLELDTDGIWCIFPQTFPENFTFILKGSKKKFPISYPCTMLNHLVHAKFTNHQYQILKNPDEHEYETIKENSIFFEVDGPYHAMILPSSKEEDKLLKKRYAVFNKDGSIAELKGFEVKRRGELKMIKNFQSQLFKVFLEGSNLEECYAAVARVANQWLDVLYSKAVDLEEDELFDLISENRSMSKSLEEYGAQKSTAISTAKRLGEFLGDQMVKDKGLNCKFIIAAQPAGSPVTERAIPIAIFSAEPAVMKFYLRKWLRDSSLQDFDIRSILDWQYYLERFGGVIQKLITIPAAMQKVANPVPRVRHPDWLFKRVMALDDKFKQHRITDAFKPAEKRPYGGDGVMDLEDFGSSGRPSDAPVRPVVHKMTKSGKNKGSSSLQQEKSLEEQVLELELPEEMPDMLTDYHGFLAYQKIKWKRQKLERAQRKALGQSRAKGPAGSLSGFIQKQSTNILTKFWQIIQIVETDIPGEFRLWVLIDKTLHSIRLSVPRIFYVNSRVEDASNETRKFPKQKMIRTLPRAHPCLHLYQFNMPESMYQRESKNLSSFFSHPDVEGVYETQLPLLSRAIINLSCICSVSNRAKRGLDEGFDLSDLKTENMDKMPYLQDDRTLNYLYLYHATTDTRHLFALFSSVHNRVNIFVVDAPGQRGQMPNMSRSYESVKTEIDRMPAETRRANKAWDYPEALQFDVDYVSSEREASRGLAKCLSKYQDERRGPTAVILHSPRTRQKLLENIGILGDFPLISMPCSKNTKPFQALAWQSNATKRMLAQFLTVGGWITEQIALARYANIPLCNIEQDSPIFVTDVWLARQLVRHDMLLWWSPSSKPDLGGREDDENVSGTEELQDPNINVPGQYETVCLEMDLLHLAVNTLLQSSLINELEGGTETALDASHTLDDYRSGKVSNVISFGTGTASSQAFAIIKHMVRTWAVDLAETRNMFAESMVGHFHRWLTSPGSKLYDPCMYALMHGLMKKVFFQLTAEFKRLGSRVILGNFNKLTIVTSKPSVGNAYAYCSWIIRHIQSKPLFLTIDLIPVNYWEQLIWMDCANYGGIICPNPEEVQEQDFAVLQAQVYRKVRMEWNIQKYLPVALHSTFEETINEFIVQVYAYRHRKQLATPNGSAATSNQNGQQDDDAAGDTVNGSAVATKADKNNREVVAYKKKLIAHAISRKLLDALPKILVQKRDSLKDPQLAVRFAFPRQPGSHLELTNPPLELIKSIAAVLGIDTSIEREVRVMRKNLLDLIEIREFAPESTFQNPCESFVLRGVICSYCSYCQDLDFCRDQQLLPKINKNTGEVSLDPWKCPECKEEYDRDAIEESMVAIVERMTNQYQMQDLKCVKCRRVKPDFLGEWCECSGRFVTALGRVEYLRKMRVFENIAEFYGLALLKEIVGWMLSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3F2</accession>
    <name>A0A9P6N3F2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">60S ribosomal protein L17</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPL17_1</name>
        <name evidence="5" type="ORF">BGZ80_007980</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000042">
        <property type="protein sequence ID" value="KAG0023798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3F2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00336">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.470.10:FF:000010">
        <property type="entry name" value="60S ribosomal protein L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.10">
        <property type="entry name" value="Ribosomal protein L22/L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001063">
        <property type="entry name" value="Ribosomal_uL22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018260">
        <property type="entry name" value="Ribosomal_uL22_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005721">
        <property type="entry name" value="Ribosomal_uL22_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036394">
        <property type="entry name" value="Ribosomal_uL22_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01038">
        <property type="entry name" value="uL22_arch_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11593">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11593:SF10">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00237">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54843">
        <property type="entry name" value="Ribosomal protein L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00464">
        <property type="entry name" value="RIBOSOMAL_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0023798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="180" mass="20272" checksum="1429C4D39FA01452" modified="2023-09-13" version="1">MVRYAATPANSSKTALSRGSYLRVHFKNTREVAAAISGMKLQKALTYLEAVKDHKQAIPFRRFNGGIGRTAQAKPFGVTTARWPVKSVEFVTDLLKNAQSNAEVKGLEQEALVIKHIQVNQAPRQRRRTYRAHGRINPYMSSPCHIEIILSEENEAVKREVEAKKPKLNVRQLAARARRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3J1</accession>
    <name>A0A9P6N3J1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Amp-binding enzyme</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_007270</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000037">
        <property type="protein sequence ID" value="KAG0023909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3J1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056881">
        <property type="entry name" value="Mug62_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22754:SF32">
        <property type="entry name" value="DISCO-INTERACTING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22754">
        <property type="entry name" value="DISCO-INTERACTING PROTEIN 2 DIP2 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24919">
        <property type="entry name" value="Mug62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="2">
        <location>
            <begin position="67"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="Meiotically up-regulated gene 62 protein-like alpha-beta" evidence="3">
        <location>
            <begin position="657"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="2">
        <location>
            <begin position="869"/>
            <end position="1127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="263"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="388"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="497"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="285"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="396"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0023909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1127" mass="124415" checksum="B9966441A4D9C464" modified="2023-09-13" version="1" fragment="single">MERPGINVSELGGKQMLPLEPRTISGPTLDDITMTPMAQFSNIIDILRFRGTITKSPTVLAGGETIQVNPDTSAFSVVNDKGRETGTCTWANILGRAEKISQTILLKTQLRHGARVGLVYRRSEILDFLAAFYGCMMAGMTAVPINVIEEFAEMVYILSYTQTELVLTTEYNHKVLARDLRAHKGMNWPADITWWKTDTIGNNSWKQKKEEGTASAESWPRLEIALPELAYIEYTKSPNGELKGVAVSHRTIISQCHAIKHGLGSNPNRKRDPLISSIEIKPTSPIGNSGSYREQKTSASLPKELSRNPVLLSKRFKPDVVMSWLDPRQQVGLVLGGLLGVYRGSHTIFLHSGVTEIPGLWESCAQRYQATVALGDYGGVRELIRTRSGKQDIQQPSPSSPSSPSSPSSPSSNSLSSLETFLIDAVIVQPMVDRKFASEFLTPLGVINPEKVIIPISSLPEHGGMILSMKDHLMFPRGADLIDFGFEYDVPREPILETGMGSGVGGKAEPPPRPRGHSTDSDTCCYYLLDREALKSNVIQVITTGEEAIKRVSERGAILVGAFGYATPRATLAVVDPDTTALCQPNRVGEIWIDSPSIAFGFWELPKHSQSIFHALPLIVPVDTMIPEVYDPVPAGFLRTGLLGGLIEGRVVIFGLYEDMIQQEAPRKPNNDTAAEQRPTTFDCHYTTDIVNTVMERIRGFNACIAFECYINNERLPVICAETPRRQRAELTKLSEFVKQALQDYHGLRPYCIAIGPPGALPRAYKNGKRAVHPVLCRKMLELGRLTISHLWTTVENTVFSLAIGKDFLGGIWGPKAIMAREATMPAHSRMVQFSSCESPLKVLDERSKVNLSQFPSLVEVLVWRSVMNPEEIAFLGLDHQGKDAKAVTFRKFGMKVVSIASFIEKRGRYRQGEKVVLLFPNGIEFVATMYAVWLLGLVPVPVAIPEPSRLHEDIVMLMSLLSELRTSHLLGNSVTEEVMKQKTTMIHIKACIGARQDAYIPTVFNISKAPKVNKTLGKESGYSSPPKNSLSKTSAAVVFAHYSTDMRRTLVKVSHASLLAQCRAFKVQCRLRNGEPLVSCWKTLAGVGMLQSCGLGVYVGAPTVLIRYTDFLASPQIFFEAIERHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3K6</accession>
    <name>A0A9P6N3K6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_007283</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000037">
        <property type="protein sequence ID" value="KAG0023921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3K6"/>
    <dbReference type="OrthoDB" id="10012223at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059112">
        <property type="entry name" value="CysZ/EI24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052786">
        <property type="entry name" value="Spore_wall_assembly"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34292">
        <property type="entry name" value="OUTER SPORE WALL PROTEIN LDS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34292:SF2">
        <property type="entry name" value="OUTER SPORE WALL PROTEIN LDS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07264">
        <property type="entry name" value="EI24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="116"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0023921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="230" mass="26271" checksum="62A6880D1F8BA4C6" modified="2023-09-13" version="1">MGHSMSTWSSIILTVGETSVLVALVMGEVFKKERSKGLFKAMIKGSSVTFGPLATIDHHHHRQLKQSKKYKKSSDVDELDDSEDSINVATKESSKETKRRKRDRVRSASLRASQRVLLWFMTLPLNFFPLAGQVAFCYINGKARVPDIHRRYFDVKGMTDKERKDWIKNREHHYIGFGFACQALELVPVLGIFFSFTNTIAAALWAIDLEQEQDALRNKKLLEDAYASEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N401</accession>
    <name>A0A9P6N401_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CBM21 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_007123</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000036">
        <property type="protein sequence ID" value="KAG0023937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N401"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000164">
        <property type="term" value="C:protein phosphatase type 1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001069">
        <property type="term" value="F:glycogen binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008157">
        <property type="term" value="F:protein phosphatase 1 binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005979">
        <property type="term" value="P:regulation of glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2440">
        <property type="entry name" value="Carbohydrate binding type-21 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005036">
        <property type="entry name" value="CBM21_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038175">
        <property type="entry name" value="CBM21_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050782">
        <property type="entry name" value="PP1_regulatory_subunit_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12307:SF36">
        <property type="entry name" value="GLYCOGEN-BINDING SUBUNIT 76A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12307">
        <property type="entry name" value="PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03370">
        <property type="entry name" value="CBM_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51159">
        <property type="entry name" value="CBM21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBM21" evidence="2">
        <location>
            <begin position="155"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="448"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="75"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="448"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0023937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="468" mass="51641" checksum="F9C5257DE986ABDF" modified="2023-09-13" version="1">MPPPTTTPTTAAPTPSSNNNNNNTNSYLDRSTPQVIATPSTPIIPVRKQSPPLLKNGLPLKSAMRTPPVSTCTRLSPIRSHSSPSLSSLSSPKFVHFNSKLEHVRLFLQGEMPSCVADRETITDAGENVNTSDIKLKLINWSPVANGAFLPVNIDASEAPLRVENVELSQDQTELIGTILVQNIAFHKQVSVRYTIDYWQTKFEVNAEYKESIPSSTLDRFVFKVALDMEKSIVEKTFCFAVRYQVIGREFWDSNNGMNYQVECKRVVVSAPQPVSDLSRQMNSILLASQIQDYSKPVLKKKVGNSRYDLSSSLSAATRSTPVRYDGFPVSQTAYRPSEYITPIQSPPGYHTSLYASSPKFINPYMSAASPPEHFHIGFDQLTIEPLSSKKDGREAEFSSGLYSPYASSPAKSSPISIPAGQHGATNPHVDSSSYYDLVDRYCFYKSSPHSSPYSSYPSSPSTPCIRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N6T7</accession>
    <name>A0A9P6N6T7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006071</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000003">
        <property type="protein sequence ID" value="KAG0024798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N6T7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0024798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="202" mass="22773" checksum="22FA5E3807759729" modified="2023-09-13" version="1">MNYELQEIHEEGGVLATVEARARAEIRLQELLEVAHKQLTELRTADSEELGSLEDSDQQTEIPDNEALAEETDLSSVTGLDEDFTDEGDKRLYEEESQYNILFDIPEVKLTAEQQTQTFIDDVTENVAIGNKKVILDSLLSNFAIHDAGDAVGRAMNDRLQERTPGVLSFWVQDDMFELWLEEHSTFIGTKLLPDAASTVRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SQR9</accession>
    <name>A0A9P6SQR9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_009028</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010005111">
        <property type="protein sequence ID" value="KAF9991593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SQR9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9991593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="140" mass="16066" checksum="B901679453E1938F" modified="2023-09-13" version="1" fragment="single">AALLAKDLNRTLVIPPVSPSSHIKLWSGPRYSEFYDLKEFSAKSGISIIEWHDIKQTPENPTTDLTRHWTEFGEDFPCIPNGAIGIKNKNLYDHFRPQFLMNFKAVEPPVKDRTMGKATEYAYAKDVLLQDKDAKNPDMW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SRA6</accession>
    <name>A0A9P6SRA6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_008441</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004573">
        <property type="protein sequence ID" value="KAF9992718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SRA6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9992718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="134" mass="15226" checksum="FCF0432AF1CF7858" modified="2023-09-13" version="1" fragment="single">MSILGTTNSIDPSIVPLSKDGFSRCDTILGYKNPHSWRYFEVPGNRICWRVNVQLQSQSFVQSDAFKNSDWGSESSGSIQEDWRSFKLPLGPDHSYITIGDLINSTENNNVTKVMLEEKLYTTWHHGRVVLMGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SRC4</accession>
    <name>A0A9P6SRC4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_008273</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004432">
        <property type="protein sequence ID" value="KAF9993113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SRC4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9993113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="65" mass="7206" checksum="0B692AE6C4B5CCB7" modified="2023-09-13" version="1" fragment="single">CDETEIYLKELNTGSYTAPGETNGFKAKRKRRASVLLCVNASALSLPMADTMDDLKHLFIDTIID</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6STN4</accession>
    <name>A0A9P6STN4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Carrier domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_006224</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003063">
        <property type="protein sequence ID" value="KAG0001184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6STN4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043041">
        <property type="term" value="P:amino acid activation for nonribosomal peptide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19544">
        <property type="entry name" value="E-C_NRPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.30:FF:000010">
        <property type="entry name" value="Enterobactin synthetase component F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1200.10:FF:000005">
        <property type="entry name" value="Nonribosomal peptide synthetase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.38.10">
        <property type="entry name" value="Luciferase, Domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020459">
        <property type="entry name" value="AMP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF1">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00154">
        <property type="entry name" value="AMPBINDING"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="4">
        <location>
            <begin position="163"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="942"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0001184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="942" mass="103819" checksum="20A08DE4E4DD5FFB" modified="2023-09-13" version="1" fragment="single">PVAIGVVGELYIGGAGVANGYINLQELTTEMFFADPFSSEPGERMYKTGDLVKYLPDVKIRGFRIELGEIEVRLAEHAKVREVAVLALGEGSDKSLVAYVVSNPADNLIAALREHLVATLPEYMIPSAFVRMDAFPLTNNGKIDRRALPKPDSESFVTKDYVAPQGEIEIALAGIWSDLLKIDQVGRHDNFFMLGGHSLLAIQMNARLRRLELNLSMRALFEKPMLSALAASLGNHRDVFVVPLNVITPETTMITPEILPPIDLTQCDIDCIVAQVPGGVANIQDIYGLSPLQDGILFHHLLVTKGDPYLLFQCTAFDTRELLDSYLAAFQNVVDRHDIMRTAVMHESMTSPAQVVLRKAALSITELSLDLADGPILDQINKLYDPRQHRISLSDAPLIRFSTVQDVDGRWILRQQWHHLIGDHSTLEVMYEEIEAFMNGRGDSLPAPEPFRNVVAQVRLGVTVEEHERFFSKTLSDVDTPSFPYGMSDVYNDGADVTEAHLMLPQELNDALRGHAQRLGVSLASLCHLAWAQVVASTSGQSSVVFGTVLFGRMQGGSGSERALGLFINTLPIRIDMEGSSVVDSVRTVQRDLAALLEHEHASLALAQRSSGVPSGTPLFSSLLNYLHNSSTSHETEAMSGMEGLSGEEERTNYPFVLSVEDFGSSLGLMAQVVHPYESTKICRYMEQALVNLANALCQAPETFVHELGILPAEEHELVVHSWSNTYTPYPSDRCVHELFEAQVVNTPDAIALVHEDLTMTYCQLNRHANRLARQLVAADVGAFLAIVKVGATYVPIDVKAPLDRQMYIASDSGAKLLITNESRDIPVQLDVTVLRFHVDDENTIDEQDGNLHLPCSSTDTAYIMYTSGSTGRPKGVMVNHRGIARFVINNGFAPIDAEDRVAFVSNTAFDHNTFDIWAPLLNGARIVIVDHEIHCHAKLHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SUJ0</accession>
    <name>A0A9P6SUJ0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Canalicular multispecific organic anion transporter 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ABCC3</name>
        <name evidence="12" type="ORF">BGZ80_005637</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002778">
        <property type="protein sequence ID" value="KAG0004292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SUJ0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000997">
        <property type="entry name" value="Multidrug resistance-associated protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF443">
        <property type="entry name" value="MULTIDRUG-RESISTANCE LIKE PROTEIN 1, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="406"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="438"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="96"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="403"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0004292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="495" mass="54261" checksum="DBCA42CEE602D8BB" modified="2023-09-13" version="1" fragment="single">MGRPLGLISLTASHITALRNANVRIQKFLLLEEIDTTVVERYSRQISSKDPILGADGKLLSVEIENGTFSWEKIVNVAVAPASLTPAQAERQPLLAPSSSLSSGSSTPFRPVLSNIHLQIPEGNLTAIVGRIGQGKSSLLNAIIGELYKQQGTVKVFGDLAYVPQQAWIINASVRDNILFGKPFNQEKYDHIIYASGLIPDIEMLPAGDSTEIGEKGINLSGGQKQRVSLARAAYQDADIYLLDDPLSAVDAHVDQHLWEHLIGPDGILKHKTRLLVTHGIHHLDSVDQIIVMKDGMVSETGGYRELMDAKNAFYQLISEFSVQEKKKQSTVTEGENVATKVDVVSAVKAKAGTDESKPISEPAKNGKASKGGLVTAEKVEEGKIGWRVYLEYAKAISIHNAIICLFLYGFAQACQVATNFWLRYWVTADERGDSHSIAFYLSIYAALVALYLVVDVSNSYMTNVICGLQGARTLYTRLLERVLRMPMSFFDTTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SUN9</accession>
    <name>A0A9P6SUN9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_005446</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002689">
        <property type="protein sequence ID" value="KAG0005391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SUN9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36182">
        <property type="entry name" value="PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G10930)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36182:SF1">
        <property type="entry name" value="PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G10930)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0005391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="174" mass="18666" checksum="B626D2C554AA917C" modified="2023-09-13" version="1">MCKWPSSFPGTRPVLKAGTTINSMIDVGAYHKGGSCQFTLSYDNGTTWVVFQDIFQTCMGDASNGINYTLPFNLPASAPSGPAILNLIWNNNEGNREIYSSCADVVIDGTNGGSLSGVEPLIANYGPNTPFIQEAVLANGNYGQAYFAARKPVTVTVPAKTSSKRRSLNRIVNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SW21</accession>
    <name>A0A9P6SW21_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_004945</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell envelope</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002471">
        <property type="protein sequence ID" value="KAG0007207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SW21"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02966">
        <property type="entry name" value="TlpA_like_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050553">
        <property type="entry name" value="Thioredoxin_ResA/DsbE_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42852">
        <property type="entry name" value="THIOL:DISULFIDE INTERCHANGE PROTEIN DSBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42852:SF6">
        <property type="entry name" value="THIOL:DISULFIDE INTERCHANGE PROTEIN DSBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0201">Cytochrome c-type biogenesis</keyword>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="5">
        <location>
            <begin position="85"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0007207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="251" mass="28130" checksum="0845CEC673AB3E1D" modified="2023-09-13" version="1">MAQNPPLTHAEKLLVEAYTNILNDPFEDKYEDKWEDGPFDRAIDEFKARAQEIGFSDPFQLLSRYKILSYEAIRTQLKNGPSPCFRPGWESPFLGATVDLTSVLAKCEHLSGPEFDSNHRIVVLDFWASWCGPCVQSGPEISNLADEFAGRVAVVGINNESIFGVTKPPEVELLQEFLNENRDGFRYTIYIDNAEGYAKETVYNPTGYRGIPCAILLVDGVVRYVGPPQENLRPALEKVLKAAEITAAHEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWH5</accession>
    <name>A0A9P6SWH5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ethanolamine-phosphate cytidylyltransferase</fullName>
            <ecNumber evidence="10">2.7.7.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">CTP:phosphoethanolamine cytidylyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">PCYT2</name>
        <name evidence="14" type="ORF">BGZ80_003649</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="9">Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from ethanolamine: step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytidylyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.14" evidence="10"/>
    <dbReference type="EMBL" id="JAAAID010001983">
        <property type="protein sequence ID" value="KAG0008254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWH5"/>
    <dbReference type="OrthoDB" id="40021at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004306">
        <property type="term" value="F:ethanolamine-phosphate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006646">
        <property type="term" value="P:phosphatidylethanolamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02174">
        <property type="entry name" value="CCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02173">
        <property type="entry name" value="ECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041723">
        <property type="entry name" value="CCT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044608">
        <property type="entry name" value="Ect1/PCYT2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45780">
        <property type="entry name" value="ETHANOLAMINE-PHOSPHATE CYTIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45780:SF2">
        <property type="entry name" value="ETHANOLAMINE-PHOSPHATE CYTIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5 14" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="7" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cytidyltransferase-like" evidence="13">
        <location>
            <begin position="15"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="Cytidyltransferase-like" evidence="13">
        <location>
            <begin position="210"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="345"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0008254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="381" mass="42835" checksum="CF20270004F15156" modified="2023-09-13" version="1">MSVSAEKRKPVRIWVDGCFDLMHFGHFNALRQAKAMGDYLVVGVHSDAEIEHHKGPTVMKEDERYAAVAACKWVDEVVPNAPYLTSLEWMDKYNCDYCVHGDDITTMADGTDCYQVVKDAGRYRECKRTQDISTTELVGRMLLMTKDHHKRSSFSGSSISAVNTAELGTFSTGGSKTKPDTKISHFLPTSRKIVQFSEGREPKEGDKVIYVDGTFDLFHTGHIEFLKRAKQMGDYLLVGIHDDQTVNAVKGVNYPLMNLHERVLSVLACRYVDEVVIGAPYSVSDQVLEKVYKVDLVVHGNTPSLNDADGEDPYKLAKERNIYVEIDNPQNSVTTEAIIERIITHRKLFEERQRRKEQKALLEKEAEKAEKAAKAAAAASQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWP7</accession>
    <name>A0A9P6SWP7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003082</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001797">
        <property type="protein sequence ID" value="KAG0008758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWP7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="405"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0008758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="435" mass="49376" checksum="0ADEB03A64A8D3A2" modified="2023-09-13" version="1">MTTIKTEAQQAVEEITENLTNPGYFLSNRPFFYNANDYFASCCGQKTSKMLENEWLTVVIPSLKASNIKALSDAGVRLEKQWRLSRETRRQRSEDGDSVKMRKLMKSSLYQHRKAVLDHSGETMRDDLHALGPSLGPSLTQPWSSAYTPPYQPNPDSPELLTFSPPSPPELTARNETIDRQEAHAFFTSAGSLQDVLLSNLSEGHTLPQWAKSRPSYTFKLQLQDDWGSWVTELYESAKTKVHLNHNHIDEIALLSGILHLNKTHIGFSAKEIAKIHSDVLRTFYNKEMEDKDIERAQDAAAIWASWMQKWKSIVLKEKLAAESEGRDPEAVNAEPVVDAIMSSYSECKTKKIMPILFIALHVFRRYNNWAALTSESDRMMAVVGPILQEIMDIQHIIRFTCSNTPTSAGKHRKTKLQQEGQSRQPDIIGKTNEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SY15</accession>
    <name>A0A9P6SY15_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_001048</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001231">
        <property type="protein sequence ID" value="KAG0010974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SY15"/>
    <dbReference type="OrthoDB" id="5340910at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14604">
        <property type="entry name" value="SH3_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040150810" description="SH3 domain-containing protein" evidence="5">
        <location>
            <begin position="30"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="195"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="6">
        <location>
            <begin position="261"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="59"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="239"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="82"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="95"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="158"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="169"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0010974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="395" mass="40976" checksum="5B74A4856ABC0BE8" modified="2023-09-13" version="1">MRYSPNYHALAVVAFIAISGSLLSSTTDALPISNNALQPLQNTESGIAHRNYLFKKRGASDPLLPSISSPQSKSPSADSTSNSAPKTSQTHNSDPSPSKAPSPSSSPAQAPHTTSTSSAQSPSKSSNPSPNASPSSSASHTSTKATKQSSAPSASASRTTPNNDSIVASGTNSVAQSSASSSPGDSVPTQVSQNVLIGIGAVCGLLVFVFGAMAFCRHRKKKNLATALLQQTAQFNHNNPYAKMSEPTTPSKESLPTAPTRPLGTYNVVATYTPALADEIEIGLGESVTILQEYDDGWCLGVNNSRNGIQGVFPRHCLEGYKNGAQYGGGNELGYYPPNAGFKAMANKRMSSIPAGGWNNGPPGGYNGDGGYGNYPSKPMPQYNDQGYYNGGGGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZ33</accession>
    <name>A0A9P6SZ33_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thioredoxin reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">TXNRD3_2</name>
        <name evidence="2" type="ORF">BGZ80_011523</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000936">
        <property type="protein sequence ID" value="KAG0012772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZ33"/>
    <dbReference type="OrthoDB" id="418495at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015038">
        <property type="term" value="F:glutathione disulfide oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03419">
        <property type="entry name" value="GRX_GRXh_1_2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011899">
        <property type="entry name" value="Glutaredoxin_euk/vir"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014025">
        <property type="entry name" value="Glutaredoxin_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02180">
        <property type="entry name" value="GRX_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45694">
        <property type="entry name" value="GLUTAREDOXIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45694:SF18">
        <property type="entry name" value="GLUTAREDOXIN-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00160">
        <property type="entry name" value="GLUTAREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutaredoxin" evidence="1">
        <location>
            <begin position="18"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0012772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="105" mass="11923" checksum="383588B6079B265D" modified="2023-09-13" version="1">MSNAIKNFVEKLIRENRVMFFGKSYCPYCKNAKSILGGRGIQFKEYEIDLEKNGPQVQQYLLEKTGQRTVPNIFINARHLGGNSDLVAAQESGKLDTMLNHKSEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZ72</accession>
    <name>A0A9P6SZ72_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Maltase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">BGZ80_011205</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="23" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="23">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Lumenal side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the EROs family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000873">
        <property type="protein sequence ID" value="KAG0013248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016972">
        <property type="term" value="F:thiol oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034975">
        <property type="term" value="P:protein folding in endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06602">
        <property type="entry name" value="GH31_MGAM_SI_GAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14752">
        <property type="entry name" value="GH31_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1760">
        <property type="entry name" value="glycosyl hydrolase (family 31)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007266">
        <property type="entry name" value="Ero1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037192">
        <property type="entry name" value="ERO1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030458">
        <property type="entry name" value="Glyco_hydro_31_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048395">
        <property type="entry name" value="Glyco_hydro_31_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025887">
        <property type="entry name" value="Glyco_hydro_31_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000322">
        <property type="entry name" value="Glyco_hydro_31_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762">
        <property type="entry name" value="ALPHA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762:SF133">
        <property type="entry name" value="P-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04137">
        <property type="entry name" value="ERO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13802">
        <property type="entry name" value="Gal_mutarotas_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01055">
        <property type="entry name" value="Glyco_hydro_31_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21365">
        <property type="entry name" value="Glyco_hydro_31_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110019">
        <property type="entry name" value="ERO1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00129">
        <property type="entry name" value="GLYCOSYL_HYDROL_F31_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="11" id="KW-0249">Electron transport</keyword>
    <keyword evidence="9" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="10" id="KW-0274">FAD</keyword>
    <keyword evidence="6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="15" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="17" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Glycoside hydrolase family 31 N-terminal" evidence="21">
        <location>
            <begin position="129"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 31 TIM barrel" evidence="20">
        <location>
            <begin position="288"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 31 C-terminal" evidence="22">
        <location>
            <begin position="788"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="23"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="491"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="1485"/>
            <end position="1515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="511"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00041343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF01055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF13802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF21365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="KAG0013248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1620" mass="182301" checksum="18A3C62DBA24EB8A" modified="2023-09-13" version="1">MSKQPVPTVTKTAAKATEPFTADYKVLSTDPPLEKQLPRGNATDPASLPLEKLENLHLQLGLVRNARLGPAFGPDPKQLTMKIHAQSSSRLNIEIENAYHQAWKVPQSVVPRHPPRVPFARQPGHTLDYEVVWNNSESFAFTVLRKGTGEKLFDTSSLGLTMKDQYIEFSTHLAGGIAGRVVSLYGLGENVGPLRREPGTTATLWARDCPCKPEKNLYGCHPFYMEILPSGSAHGVLLLSSNGMDVILSPQGDRLTYKVIGGIIELYIFTGPTPQQVIQQYTELIGRPCMVPYYAQGFHICRWGYDTLEKVKDVVSKFKDHSLPLEVMWIDIDYMKDYKCFTFDEERFPTKKLAEYVDELHSQDQHIVMILDPGIKVQYQTGLYEPYDEGVAKNLFIKRRVTKFEEAGDGTKYHAGQLVDFVGKVWPGKTTFPDWFHPETQAYWTKHITQFYQKIRLDGIWIDMNEAASFHDGDCSHIESSEDRPVRLSDFASAEPEGSDAEEEGTGRVLQPQHQQQPQHVDSNPRKRKQSQTSDTEADHSPESVQPKEVIAEHEHDYERKHDPGFPEKHGYNANLQSVGNNTDADKDELPSGTKLPVVYARPKMPPYRINNNNEYADLEYRTISPDALHHGDVIEYDVHNLYGHMEAIATYNAIRSISPEKKPFILSRSTFPGSGQYACKWNGDNWSTEYDMKASIPGLLNFQFFGISMIGADIGGFGGSATEELLIRWHQLGAFYPFMRNHNCITNPPQEPYVHKGLIEVSRTYLDMRYRLLPYWYTLFFRSHQDGRMVCSPLWVLDPTDQDLLSNDEQFLVGESVLVSPVLKLEQDSVNARFPTGRWYDMHSGVLEVYVQSKGENPKQAQQGASKVLAVDAPLNKIPIHLRGGNILPRAGIEKGTFIRTTSQVRKAPIQILVALDETDCAVGEYYHDDDSFAAADGTLVKFQARPGFLGMSSFSAKNLADTAVFSGKERASNVADVMVPSGNRDLRPTFVESIMVWGVGIGQVESNKVLKAEAASSSCQVEPLQVRISIVKHVAASEESVQHRRELSAVPNEEFVVQSVQVENSVCDYDAVEIINQEMRKQLQSLVQQKYFKFYKLNLYGTCPFWTENHLCMNKDCGVAVVDESTIPQEWTSTALGAISSPTNGKNFQPFKSCQLKDQDFCQVDDEAISEGVYVDLIENPERFTGYSGPSAAKVWDAIYDENCFNIAQKMQLASDCEQCSLDRQADEELLAGKLKAAAMTGISLARNPIADAELEQRKPLDRQDEEEFGYETPVFQPVYVCAALEKMTKLTNSSSTWTRIYSQGPNLDCFVSRVGAHPDRLENIYFDYAILVRAVTKLSGYLKNYEFCTGNPEEDAGVKSMVDRLIDTSSKSPAIFDEKAMFVGPEAQALKLEFRDHFRNITKIMDCVGCEKCRLWGKVQTSGLGTALKILFSYNDEHLNPIKNPNLLQRTEIVALFNTLNRFSESVDSITKFREMYMQQHGPRNTHVENPVPSERQQHPVAPESAPTAVDDKAQSSASVSSIMPFFTSVLEGHVILPDQDPTSNPQNEPLLSSYSIGQHLLKAKVLIQDTREWMKKKGFVLSNTILGMSRMPLTFFSNDQRQAHKKNHPEGNKKDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZI5</accession>
    <name>A0A9P6SZI5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BGZ80_010913</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000812">
        <property type="protein sequence ID" value="KAG0013705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18596">
        <property type="entry name" value="ABC_6TM_VMR1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18604">
        <property type="entry name" value="ABC_6TM_VMR1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14306">
        <property type="entry name" value="UBA_VP13D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
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        <property type="entry name" value="ABC_transporter-like_CS"/>
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        <property type="entry name" value="Ankyrin_rpt"/>
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        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
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        <property type="entry name" value="VP13D_UBA"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER ABC4"/>
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    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="ABC_tran"/>
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    <dbReference type="SMART" id="SM00382">
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    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
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    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1851"/>
            <end position="1874"/>
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            <begin position="2642"/>
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            <begin position="2667"/>
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            <begin position="406"/>
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            <begin position="752"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="13">
        <location>
            <begin position="1703"/>
            <end position="1993"/>
        </location>
    </feature>
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            <begin position="2066"/>
            <end position="2309"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="13">
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            <begin position="2372"/>
            <end position="2692"/>
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            <begin position="2732"/>
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            <begin position="2850"/>
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            <begin position="1"/>
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        </source>
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        </source>
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            <dbReference type="SAM" id="Phobius"/>
        </source>
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        </source>
    </evidence>
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            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0013705.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
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    </evidence>
    <evidence type="ECO:0008006" key="16">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="3028" mass="334614" checksum="F529AD92E9346441" modified="2023-09-13" version="1">MSAQANTANTIPALSSSTSPEFASASVELHVDGQWPIESQKDKDEQIQAFCREYAKRIATALTQHDNTGGVSSNTRLSEPAQEKGKEHIAWPSPEALMELYRKLLRDSQDPKIREVMSDQSSVVSNFATSLAEKLEQQLGSSRQQQLPRQRMPCGCGVDHGDQDQLDFPDDSYEDEPDEEGFDSEEEDDDGDEDDEDDEDEDDEDYDDEDDEDDEDEDDDDDDYDEVYDEDLDHDILDGYSRHYARNSIAALALEEEKRMFASISQLRNDKNLLEEGLRKKQQYDAQKKKQEEEERIRLLQRLRLEDEERRRREQQEKERKERLEQELRKKREAAEADQAARSFLFISTSKSNIEVVKTMVEASPAESESIAGIPKFTSTSATRLTGWEYIGEEGSGKDVNEKSGLQETLLHVAARVGCLGLVSYFIAKGAPLDALDSDGRIPLHTAAKHNASPEVCKLLIEKAAYYIDRHSIKSGKTALHYAAQNGCGDLVAMLLQHHARVNVVDAEGNTPEMLARAGLDREKSSKVRAQKYRGAIHHIQKSLAAIKEAQRQKDALLEEQRKKEEELAKEEAEKDKAARRKQEEKLEADQRRREEEEKELARLKASVADPHGHSGTGSKKKKKKKGKVNNEVQQPHKEILSDKTLPSPAPAYSTVAKSTSPSPMGSPSISQAPLSIQKPSAQPSAHTPGSTKMSALSSSTPSNAKNSSSTSIPPSDAKSLPSSSVSEASKLAKPTNDWPSPPRLPKVKTNYRPSQLVVARMVDMGFQRRDSRKALIQTEGKVEEAIELLTSGAPLADDSEDEAEKAALEAARRKAVAKKTAASTPTVKEQNSSVKAPVIANPQPPQSQTAPVTPTSKPPVPLQSPPSQQSSSKTSAPKKPAALPIQILNRPPVLPPHVQMRAAPTQVLQRSSMQTRISPASSSNKPSTSQGSSTSSQTTSRAATAPSAAPFLAQRSAPPPPPTRAPYSYRSSSTQGQSQQFSTATISSSVHQNIVSQVSGSTLFSTPSPTSNTPSSHHRPHDSRGANDLSLHSLPVTGSDYIRSPNVSTGWNIGLSVQNSVLSNVSEVPLVAQNTSWGMAAPTNAASTFENNSISFQSLSSTSALTAQRRSSLELLTASMSEMLRQSQMDMDGDTDNDMIKDVLAMTGAIDPDDLESTLSNFPLADSSSSEPAASRVTIRPSIAVGEGRNQPSLATRNPVASLWEYGSFTQDISNISQSWSSSPSQRGLAVDENNIRDYNQWNSSSGIEVDQSVHQMQYQGSSSPLATDRQQAYASTYINHLFGSPSSPHTSLMPGTVPVSRGIQTASPRPTAANNSDGLSQSVGVNSNTSYDRELSHQIFDFNDSQYQTINNNLGQEATSNYYSEDHYSSLANQSAAKPFSGSPQSASSVGGLSYSSSADINSNLVSASNSATPPISSSDSRHLLVESTLPLVYSLASVLLIFYLSKKPVNLDQYEQLRDSLDNEDVFHAQNTQRQRGETAFSDSTPVSSIQTHRASGLSINLARFGLTALQLGLTVFAATLIQNEKSSEDQSAEHYTLLKDGIKTLAWSYALALSLVHLIRPVLAYQFWVRPQMDFFYVLELILSSIELYRSDILDLPVSEWPFSLKMAVASWSTTALLILVSILTKPNRKLIPVQFPKEGEVLRTPSTEYSSSFYSQITFSWMNPLIYLGYQRTLQDVDLPELEPADLSKSSSREFRTSNCLALAQPYCLNKLIKYIECKDCGAPTIHDYTWVFVLLFTSTLESAAQQQALHQGRRLFVHLVSICNSEVFAKALRRKDVTSSVEKGDGDKKEKDGEKKKNRPLNISNLVGVDIQKMEQAFCYAYHYYGIPIEFGLSAYQLYYLLGNAAWIGIGFMIVTLPIPALLFRVFMKLFKKVMESKDDRIDYLNEMLSAIRIVKFFGWESKFVEKITASREEELKQIKKSYIRASFAGIAWMIVPLCNIVVFFVSYTKVYGNEVSASVLFTTLSLFNIMNNSLQSIPWAIMSVMRASVSLKRIAKFLDEDEVIRDTTVTRIDGKVRVHSSSHPIVGFVNASFVWPNKENDKVTDENTPKKSWFQNLKSKFSKVPAVETPVAEPEAVADRFKLKNISADFPVGQLSLIVGPTGSGKSALLLALLGELDRLEGDVYLPRLDYGAAYANNRGSGIAYVSQTAWLQSSTIRDNILFGKEFDQTRYDEVIEGCALVTDFQILESGDATEIGEQGITLSGGQKQRVALARAIYSDASVLLLDDCLSAVDTHTGEKLFQTLTGPLLEDRTVLMATHQVQLTLNAARYIVVLEKGEIIGTGTPELVLRNGWVDNVALSAPASDDSSEVSTLEGEENNKKTKKSDSKKVGTKLIEEEKRIEGSVSFKVYLTYLAASGGWPFWIGVVVFLFLREAFNFANNAWLAIWANRMAESTGSFAIAVFDTVMPEPIALFVYSAFTPKNGGSSFMARTLFGGDEVGSVEYYLGVYILLSLAMAFCGAFSEYYAMVVGNIRGSRVIHAKLLHKVVRAKVRFFDTTPIGRIINRFSTDISTIDDQVLRSLESFLNYIMMVIGIIFTISFSTPSFLIAGAFIVAIYAVIGILYLPISRDLKRLNSNFKSPILNHFNEALTGIATIRAYGFEGRFLSKNLVNLDNNNRTFFLLWSTNRWLHWRVDVTGALVSFITGMLILQNWDSIAPGWAAMSLTYSLRFTMTIVWIIRIYAENEMNMNAVERVCEYMELEEEPPAIIEGSRPPASWPHAGEIEIDHLTMKYAPDAPEVIKDVSFKIKAGEKVGVVGRTGSGKSTLAISLFRFMEPTHGTIHIDGIDICKIGLQDLRSNLTIIPQDPILFKGTLRSNLDPFGEREDRELWEAIRRSHLIPAETVKRQGTETPVPGTSSNTPAGKSPATSVKDTQSDESDIADPSKITLDTPVKENGSNFSQGQRQLIALARALVRQQKVIIMDEATASVDFETDLKIQTTIREEMADATMITIAHRIRTIADFDRVLVMDAGVIAEFDKPYTLLQKEDSLFRSMCERSSEYETLRAIAEAKEQRDAQRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZI8</accession>
    <name>A0A9P6SZI8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_011114</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000854">
        <property type="protein sequence ID" value="KAG0013371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZI8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="14"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="115"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="149"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="219"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="309"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0013371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="358" mass="40126" checksum="ECA3FE99A3EB7CBF" modified="2023-09-13" version="1" fragment="single">MADTTNKKLLRSKFILTAYSLTAAALMGSSIGLVAYQSRQFFFLSQASRHNLLHLPYLPHGYDDYGFNHTHGDHPPSPPHHPPHHPPPPSPFPDHPPPPPPCHQFEQHGHSLLSFFLSTFLPVLAWIGTVFLCAAVINSKEWIPKVVSARKGLLLSQFMFSVFWIMLASIQDVQERLVAQKRSSMEMNPDVETIEDITYIEAAHEFKRHISSLVIPMSVIWYMAVVILGVATGLLITCSNLLERQLNGDQHMADAISKEEQCLMSYEKHDQEKELTMGSEKCQGAGTTATMTTTTTTASSLSRYTKRQCFILVSLIFGLFMSQMKLFEWIIRAQSLDSYHEGTTESVASFLAFVGLVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZW0</accession>
    <name>A0A9P6SZW0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_010472</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GILT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000730">
        <property type="protein sequence ID" value="KAG0014406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZW0"/>
    <dbReference type="OrthoDB" id="958254at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016671">
        <property type="term" value="F:oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004911">
        <property type="entry name" value="Interferon-induced_GILT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13234">
        <property type="entry name" value="GAMMA-INTERFERON INDUCIBLE LYSOSOMAL THIOL REDUCTASE GILT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13234:SF8">
        <property type="entry name" value="GAMMA-INTERFERON-INDUCIBLE LYSOSOMAL THIOL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03227">
        <property type="entry name" value="GILT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040264735" evidence="6">
        <location>
            <begin position="26"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0014406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="243" mass="26674" checksum="0F7B7E92BF3169F0" modified="2023-09-13" version="1">MKYSTPSLLATLLLALSSSNNIAVANTPLTIKKSPVDVIQAENLPAIHPSLSFIGSIERITTKSAPVLDIEESGSLISTSASTTATKVTCKHGPLECAGNTQQLCFKKFFPDHEVWVPFVAAMNSWEPRRIGEPKYAREVAERVLSDIKNYISVPLLDRVDDCAKSQEGFDLLVESVQNTIDHGVSTSCTVFIDDKKRCVVDGGIWRECPEGSSVEDFVRSIKDAASRLTINFVNSRLFRLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T009</accession>
    <name>A0A9P6T009_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_010062</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000661">
        <property type="protein sequence ID" value="KAG0015078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T009"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015174">
        <property type="term" value="F:basic amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034488">
        <property type="term" value="P:basic amino acid transmembrane export from vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051415">
        <property type="entry name" value="LAAT-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006603">
        <property type="entry name" value="PQ-loop_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16201:SF34">
        <property type="entry name" value="LYSOSOMAL AMINO ACID TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16201">
        <property type="entry name" value="SEVEN TRANSMEMBRANE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04193">
        <property type="entry name" value="PQ-loop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00679">
        <property type="entry name" value="CTNS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="49"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="163"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="163"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="185"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="224"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0015078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="236" mass="26469" checksum="A6ADFADDADADC74C" modified="2023-09-13" version="1">MPALQDQGTHGIFSQGSGKPDMVGRVFARSLEGESLLGDDPSPPADQNIIILGRIFAWVCTVFYLSSRMPQLWKNFKRKSVQGLSILMFFWAAMGNLTYSLSILNSADAVNPDTRQKFLREAVPYLLGSSGTLMFDVSIFGQWLYYTGKLRIFGIGLKSHRRHRHYHPRQPGRSRSHSRVESMVLTPSGSQSGGLYNILVNENDDDDDAGVVEPNNFSTTLRPPDIERPHNEETHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T014</accession>
    <name>A0A9P6T014_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 12">Uroporphyrinogen decarboxylase</fullName>
            <ecNumber evidence="6 12">4.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BGZ80_010044</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>uroporphyrinogen III + 4 H(+) = coproporphyrinogen III + 4 CO2</text>
            <dbReference type="Rhea" id="RHEA:19865"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57308"/>
            <dbReference type="ChEBI" id="CHEBI:57309"/>
            <dbReference type="EC" id="4.1.1.37"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 12">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 4/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the uroporphyrinogen decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.37" evidence="6 12"/>
    <dbReference type="EMBL" id="JAAAID010000659">
        <property type="protein sequence ID" value="KAG0015107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T014"/>
    <dbReference type="OrthoDB" id="339900at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004853">
        <property type="term" value="F:uroporphyrinogen decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006783">
        <property type="term" value="P:heme biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00717">
        <property type="entry name" value="URO-D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.210:FF:000001">
        <property type="entry name" value="Uroporphyrinogen decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00218">
        <property type="entry name" value="URO_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038071">
        <property type="entry name" value="UROD/MetE-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006361">
        <property type="entry name" value="Uroporphyrinogen_deCO2ase_HemE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000257">
        <property type="entry name" value="Uroporphyrinogen_deCOase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01464">
        <property type="entry name" value="hemE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21091">
        <property type="entry name" value="METHYLTETRAHYDROFOLATE:HOMOCYSTEINE METHYLTRANSFERASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21091:SF169">
        <property type="entry name" value="UROPORPHYRINOGEN DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01208">
        <property type="entry name" value="URO-D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51726">
        <property type="entry name" value="UROD/MetE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00906">
        <property type="entry name" value="UROD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00907">
        <property type="entry name" value="UROD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 12" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="10 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="11 12" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uroporphyrinogen decarboxylase (URO-D)" evidence="14">
        <location>
            <begin position="26"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="Uroporphyrinogen decarboxylase (URO-D)" evidence="15">
        <location>
            <begin position="149"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00014308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS00907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0015107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="359" mass="40469" checksum="E76D2DB6394FB365" modified="2023-09-13" version="1">MEKPFPEMKNDLILRAARGEETERVPVWIMRQAGRYLPEFRKVSAEYDFFTICRTPELATKVTIQPIDRYDGLLDAAIIFSDILVVPQALGIEVVMLPGKGPHFPNPIVDPEDMHRRLKEKVDVHEDLQYVFDALTMTRHALNGRVPLIGFAGGPWTLMTYMVEGAEKAKGWIHKYPEESQELLQRITDVIVDYLVGQVRAGAQMLQVFESFGGDLGPDDFDRLSLPYLTQIVERVKYELGSDAVPMTIFAKGSFYALDSLSSIGYDTVSLNWTIDPEDAIEIAQGRVTLQGNLEPSVLLGSDQEIEVETEKMVRRFGSSTRYIANLGHGILPSVRLEAVDVFLRTVHRVGRRSVAEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0J0</accession>
    <name>A0A9P6T0J0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_010174</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000681">
        <property type="protein sequence ID" value="KAG0014879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0J0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0014879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="494" mass="56542" checksum="640F11DC4BF90D87" modified="2023-09-13" version="1">MLVVLDRYSFSFPRLLSIKYTPTDANPRDDGSMLRLVQSMPTLQNLTMEFSPFREANHAKLIETLESHPGLRKLDLICYVTTSSITTIQRIIQASRKLESVRLEFRSCGQVQAMEGSEWRNQCNLASEALYSMKDTRIRELSLQLLSADQQAAILPPLLERCPLLERLDWDCWNDSETLERITSLIRGRSYLPLTHLCLRNESNQLLDERPALDLILSLGHGNNRSTNGNGKIYRDGVGFNNEWKAIGTTIRGLETFAIYSTITFQKQGILALIQNHSETLTALDLSYTRYLGIQVFVSLLSNLSRLQFLSIALSTRLNGEESTAVEGALSTPWTALSIKCLILAIDMGTIWTGSMGDDCIGYVFSQIGRLVELEEWHLIGPKDLLTMRRTYLVHLSELKNLKSLNFSCSEDIDIDLTDAEWMLQNWTRWTHLVMYERTYRKWTSQYRQGGLMEVLKKLVDSRPWMRICGYIPGKPRDWPLRTTLNNCSCYGLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0S8</accession>
    <name>A0A9P6T0S8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Letm1 RBD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BGZ80_009352</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000551">
        <property type="protein sequence ID" value="KAG0016229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0S8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030003">
        <property type="term" value="P:intracellular monoatomic cation homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033122">
        <property type="entry name" value="LETM1-like_RBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044202">
        <property type="entry name" value="LETM1/MDM38-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059005">
        <property type="entry name" value="LETM1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14009">
        <property type="entry name" value="LEUCINE ZIPPER-EF-HAND CONTAINING TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14009:SF1">
        <property type="entry name" value="MITOCHONDRIAL PROTON_CALCIUM EXCHANGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26561">
        <property type="entry name" value="LETM1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07766">
        <property type="entry name" value="LETM1_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51758">
        <property type="entry name" value="LETM1_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="10 15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 14" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Letm1 RBD" evidence="17">
        <location>
            <begin position="32"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="278"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="555"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="407"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="278"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="315"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="348"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51758"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAG0016229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="574" mass="63762" checksum="6602FD9E6AA01065" modified="2023-09-13" version="1">MEFLLPVALKLFPNMLPSTFEDKFAEEEKKRKLLKMRLEMAKFLQETIEESGIPGSSRAEAVKEFGDFFRKVRTTGEQASTDELIRVAKLFHDELTLDNLSRPQLVSMCRYMNLNAFGTDNFLRYQIRNQMNSIKQDDKLIMSEGVDSLTTRELQAACASRGIRTTGVSTARLRSELQQWLELNLTYAIPSSLLILSRAFSFSDSKESATPVEALQATLSSLPDSLLTETELHVSELEGAATTRQKLEVLEQQEELIADELAQEKKEEEARKARKEEARIKKEAEEREKQKAQEAAGSPVTATPTDIPAFDKSTQAAEAAGTPATQAGAPELLTDAQVAAQMAKDSEATTAAKEPQQAAKPADVPTAAAPTPAAAAAAPPVTKSVEDEDAARMTEEQLLELREALCIMSSRSAVLEEREELEDLKEDRMEYKEDIEELAQVQRREHKVSKRLGSRLEKMIAKLDQELQAYDAAVGNKLQAFQANERGELTVKDIEEALKVIKHAPGAENIKQIVKKLDADGDGLVLLSHIVELADLVEQEEGTGVLVEGKKIPDKRTEEDKEKKLKKEDLLKDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T166</accession>
    <name>A0A9P6T166_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Thiamine phosphate synthase/TenI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">BGZ80_008087</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 2 H(+) = thiamine phosphate + CO2 + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:47848"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:62890"/>
            <dbReference type="EC" id="2.5.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 2 H(+) = thiamine phosphate + CO2 + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:47844"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:62899"/>
            <dbReference type="EC" id="2.5.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>4-methyl-5-(2-phosphooxyethyl)-thiazole + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + H(+) = thiamine phosphate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22328"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:58296"/>
            <dbReference type="EC" id="2.5.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>5-(2-hydroxyethyl)-4-methylthiazole + ATP = 4-methyl-5-(2-phosphooxyethyl)-thiazole + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24212"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17957"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58296"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.50"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; thiamine diphosphate biosynthesis; 4-methyl-5-(2-phosphoethyl)-thiazole from 5-(2-hydroxyethyl)-4-methylthiazole: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; thiamine diphosphate biosynthesis; thiamine phosphate from 4-amino-2-methyl-5-diphosphomethylpyrimidine and 4-methyl-5-(2-phosphoethyl)-thiazole: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="16">In the C-terminal section; belongs to the Thz kinase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="17">In the N-terminal section; belongs to the thiamine-phosphate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000429">
        <property type="protein sequence ID" value="KAG0017627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T166"/>
    <dbReference type="OrthoDB" id="4994at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004417">
        <property type="term" value="F:hydroxyethylthiazole kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004789">
        <property type="term" value="F:thiamine-phosphate diphosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01170">
        <property type="entry name" value="THZ_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00564">
        <property type="entry name" value="TMP_TenI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000104">
        <property type="entry name" value="Thiamine biosynthetic bifunctional enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00228">
        <property type="entry name" value="Thz_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00097">
        <property type="entry name" value="TMP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000417">
        <property type="entry name" value="Hyethyz_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036206">
        <property type="entry name" value="ThiamineP_synth_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022998">
        <property type="entry name" value="ThiamineP_synth_TenI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034291">
        <property type="entry name" value="TMP_synthase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006830">
        <property type="entry name" value="PRK09355.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00693">
        <property type="entry name" value="thiE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00694">
        <property type="entry name" value="thiM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20857:SF23">
        <property type="entry name" value="THIAMINE BIOSYNTHETIC BIFUNCTIONAL ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20857">
        <property type="entry name" value="THIAMINE-PHOSPHATE PYROPHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02110">
        <property type="entry name" value="HK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02581">
        <property type="entry name" value="TMP-TENI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01099">
        <property type="entry name" value="HYETHTZKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51391">
        <property type="entry name" value="Thiamin phosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiamine phosphate synthase/TenI" evidence="18">
        <location>
            <begin position="10"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00061146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00061283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF02581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAG0017627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="520" mass="55203" checksum="6CE1C383DDBA22C1" modified="2023-09-13" version="1">MPKPVVDYSLYLVTDSGLNNPSRTLLQSVEDSIKGGVTLVQLREKELDTEAFIELAKKVHEVTKKYNVPLLINDNIEVALAIDAEGAHVGQDDISCVEARKLLGNDKILGISTGTPEEAKKALADGADYIGIGTCFMTQTKSPKRTLGPIGVRTILEVIPKESELKTVVIGGIKHDNTRRVVEHSAGSHGRIVDGVAVVTGIVSASDAKIASEQLLREFRIGYENASKHIQGQCQARESVENVLKSFPPLLSTLREKSPLTHHISNYVVMNDTANATLALGGSPIMAPSAVEAEDLSKVVSSVVLNIGTLTESFVECMIEAGKHANVQSKPVIFDPVGAGATTLRENTTRRILNSMHVDIIKGNAGEISTIAKIVGCDTESIAMRGVDSLGSGFSNPAAVVQAVAKREKCVVAMTGVIDYVSDGVRTVAIKNGHSYQGRITGSGCMIASSIASFAAISPNDHFAAAVAGILALNLAGEHAARRDDVRGPGTFRAAFIDEIANLVPEQMLTEAKIETIQLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T184</accession>
    <name>A0A9P6T184_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Peptide hydrolase</fullName>
            <ecNumber evidence="9">3.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">LAP1_3</name>
        <name evidence="11" type="ORF">BGZ80_008155</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the peptidase M28 family. M28E subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="9"/>
    <dbReference type="EMBL" id="JAAAID010000434">
        <property type="protein sequence ID" value="KAG0017567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T184"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03879">
        <property type="entry name" value="M28_AAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.10:FF:000042">
        <property type="entry name" value="Peptide hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147:SF56">
        <property type="entry name" value="AMINOPEPTIDASE YDR415C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="METALLOPEPTIDASE M28 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 11" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 9" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0732">Signal</keyword>
    <keyword evidence="7 9" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040530751" description="Peptide hydrolase" evidence="9">
        <location>
            <begin position="19"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="10">
        <location>
            <begin position="175"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00043962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0017567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="405" mass="46245" checksum="906452D461E4459C" modified="2023-09-13" version="1">MVKLQTIALLSFASTALAAPTWWEQWTLNKAKDVAHRLLPHSQDKRLVQTSEDMAPVWTTEEERFDMIKNKIGFMDITGHQDFDARLHVNVKKPLPKEAHHQEKYERYVGQLSTANMEVALTKFTSFYTRYYKSESGRESARWLYKQISDLIEGAVTSSDISIRKFEHDWDQFSIIARFEGKNMSLSNSPIVIGAHQDSVNAWFPYFGRSPGADDDGSGTVTILEVFRALINTGFHPDRPVEFHWYSAEEAGLLGSQDVAKEYDYKGVEVLAMIQNDMTGYVGTKFDESYGVVTDHVDPELTELIKEYAREYGDIAVRETKCGYACSDHASWAKYGYRSAFAIEGDFSDISPYIHGQEDDVSHIDFNHMKEFAKLTLGFAIELGHFNDKKHDEEYLTKDVPCMSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1J1</accession>
    <name>A0A9P6T1J1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Protein PNS1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">PNS1_2</name>
        <name evidence="10" type="ORF">BGZ80_007602</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">Probably involved in transport through the plasma membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the CTL (choline transporter-like) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000392">
        <property type="protein sequence ID" value="KAG0018062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1J1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007603">
        <property type="entry name" value="Choline_transptr-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12385">
        <property type="entry name" value="CHOLINE TRANSPORTER-LIKE (SLC FAMILY 44)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12385:SF4">
        <property type="entry name" value="PROTEIN PNS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04515">
        <property type="entry name" value="Choline_transpo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="155"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="197"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="226"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="255"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="295"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="327"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="389"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="425"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="11"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="29"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU368066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0018062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="491" mass="53910" checksum="32428FF2F470747F" modified="2023-09-13" version="1">MSAYPPPNQPYPQHQYPPALNQQYQYGAQPPPQYQPLIPPEHQWGLQPQPGQQHFAPPMPPSYDGTVNPETGLPSKFNPKPKYNDLWALFVFLIQLAGFVVLSYFAITTVKNDGTSGPLVGFFSKSGLITLCISIGVGAVFSVVYFLLTQAFPRAVIMVTFALSILAYLAVALYYIYLKLCVMLQTVTSISKEYPATFVVAFLFLFLQIVYSIYFMVVIAGTYDRFYNTATGSAPATLYVLLIFSLFSFYWTSQVLANIAHTTICGVYATYYFMKGSPQGVTKSPTVESMKRACTTSIGSICFGSLIIAIIQTLRAIANIARNDGNGIVAFIGCLIDCLLACIQGLAEYVNKYAFAQVAIYGKPYIEAAKDTWTIIQDRGIEQIINDNLIGNVWGMAGLLGGILSAVGSYIYLRFATPAFNSNGQFTYAIIIVGFVMGLQIVFTVGTVIDSGVVTTFVCLAEDPAALARTKPELFEKIRATWPQVVQGIHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1T1</accession>
    <name>A0A9P6T1T1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006948</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000348">
        <property type="protein sequence ID" value="KAG0018618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1T1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0018618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="384" mass="44026" checksum="4C49A0C059593E07" modified="2023-09-13" version="1">MSKDDFMGMLRACPSLNNLTLEASEEIKRFEANQINLVTTINTGTMEGVEEEEEEGEEEESENHSSAKPSKKSKLSTNKLPLPSPPEFTHPSLEHLHFIGNLIPSFLQYVPNIKSLKLTTILYGDFQDLEHQLQMMAQTKQTQSTETTETKETPQCLSQLTHLYTFTKCQNPSQYMSLINAIPTPNHLVHFEGQVPARIARKFLEIMVEQQSESIERLIVIPGSNSEFQEQEYSPLGFEFNIWRILERCPQLIVLEIPYFLGYASIYITSRLKPVLHGDGSEAGIECVDIVRKIYEPIQEWVCKDLRRLYLRIKDMDRMNPMEQITFDLCVDRLVPPEERQEGDAHRKTLTTRSALEKMVLHKLSGLQKLEELNIGSGCMYGSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2F6</accession>
    <name>A0A9P6T2F6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005341</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000264">
        <property type="protein sequence ID" value="KAG0019727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2F6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046366">
        <property type="entry name" value="MPAB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36124">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36124:SF4">
        <property type="entry name" value="ER-BOUND OXYGENASE MPAB_MPAB'_RUBBER OXYGENASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0019727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="415" mass="46319" checksum="86F1CC4ABD2D55C1" modified="2023-09-13" version="1">MLGSLASSLFYESTLPASLRHGVVAVVPFAVTALKTIVTCSSVVLLCYMVLVRKRRYQGINRMLKKYPDPTLPLRDLEVANEVWSFASDWEFPFMFNFTVQMIILKLSGIPSISKIVASTKQMTNHSVKRANDTNLLLAEALQSYSRRTARSLLVDKVDPVTGTITTTPRNKLTGASADIVDDEELKERANDDARAKAAVDRINFFHSHYNISQGDFMYNLALAILDTIHLVGRFDWRPLTELEENNYELGNMKYAPTNTAMADGNIAASQSMVTTPEAKARVKKIFVGLMSPRSRAAVGYDEPTRTQVFVSRSILWVRGCIVKYLMLPRTAPHLLTAMRATKFEDVNIHNDKTENKEAAGGCPFSGGMRYVQRFNDLGPLYPRGYKIEELGPEKFFGKGPSVFPITDLKPTTVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2G8</accession>
    <name>A0A9P6T2G8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004431</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000226">
        <property type="protein sequence ID" value="KAG0020306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2G8"/>
    <dbReference type="OrthoDB" id="2445692at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="42"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0020306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="93" mass="10005" checksum="C6CAF0A844314089" modified="2023-09-13" version="1" fragment="single">PTTTTTTAARSKSRKHSSPSKLPSPSQAYTTTTMSFFRSNKNKSASAASTPAQTPRASMQGSRSSQANTMTPEQAVEIALNKCVHYSSISYRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2H2</accession>
    <name>A0A9P6T2H2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006331</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000312">
        <property type="protein sequence ID" value="KAG0019074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2H2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34689">
        <property type="entry name" value="NUCLEIC ACID-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34689:SF1">
        <property type="entry name" value="NUCLEIC ACID-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0019074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="141" mass="17007" checksum="5CB6C79F6BE54E28" modified="2023-09-13" version="1">MWNKENEFQAWLMEVKKLNPETIPHNKMKDHFIGFMEDYNTVTMPHEKFYNLTKWEDRQRAIRMGEPLPESTQGSVNLMNDEEMLRMKQRDKRKMNVSSQPQILMTQSQLQELRKVSHERVEADKLRKMGFDTGRKGVRYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2M4</accession>
    <name>A0A9P6T2M4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_003873</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000205">
        <property type="protein sequence ID" value="KAG0020647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2M4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="180"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="90"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="201"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="21"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="134"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="159"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0020647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="224" mass="24205" checksum="D674FEB4ACD81D21" modified="2023-09-13" version="1">MSATTTTTNNNNKELLHTTTQPTAYPSPSLSPATSHHPNTQQLSSTASRPRQSVKALLTSSNPPASPLDALVMALEATVDEDHNHIQQEAPDHLTDQDDDPDATIPSSPTMFMKRAPGESSLHHLPTMMLPESAASTLTQSTQPHGLSSARGASQRKMSISSQDSSSSSVNSNSERTKEYACTVGSCEKKFYQVAHLRSHERRCHSGARPYRLEKSRGKATLGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2R2</accession>
    <name>A0A9P6T2R2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Swi5-like zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">SWI5</name>
        <name evidence="5" type="ORF">BGZ80_003502</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SWI5/SAE3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000193">
        <property type="protein sequence ID" value="KAG0020832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2R2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032798">
        <property type="term" value="C:Swi5-Sfr1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034974">
        <property type="term" value="C:Swi5-Swi2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010760">
        <property type="entry name" value="DNA-repair_Swi5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28529">
        <property type="entry name" value="DNA REPAIR PROTEIN SWI5 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28529:SF2">
        <property type="entry name" value="DNA REPAIR PROTEIN SWI5 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07061">
        <property type="entry name" value="Swi5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="143"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="49"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="64"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="106"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="157"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0020832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="247" mass="28456" checksum="2B1CED7F0E55E3B0" modified="2023-09-13" version="1">MQDSQDQHPRSSQERRNRSNEQHRRERPGRGERDRNRDNESMSPRSSRRRTDQSSRLSHEQQDISEQQKALEQSIFSFIEELEGHGQGQPQAHDQELKDAGPSEPDIQDVAEPEEEGEPEIEVVEEVSIEMMIPLEPAPIPVLEQSYSNGDSQEDQESFKPTHQTKEDAQIEELKAAILELQRQEREIIQSIRGEGTPSEIISRHIKQLHRYNEIKDAGQIILGKCAELDGSTIKKQYEIYGLDLED</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2Y2</accession>
    <name>A0A9P6T2Y2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ormdl family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_003061</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000179">
        <property type="protein sequence ID" value="KAG0021077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2Y2"/>
    <dbReference type="OrthoDB" id="1932233at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007203">
        <property type="entry name" value="ORMDL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12665">
        <property type="entry name" value="ORMDL PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04061">
        <property type="entry name" value="ORMDL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018147">
        <property type="entry name" value="ORMDL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0021077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="166" mass="18775" checksum="198294C0ACAB8350" modified="2023-09-13" version="1">MTLASMYKTDYIQILDQHSQANLNSSWVNDKGAWMTNALIILFIKLFFGIIPGMSQELSWTLTTLTYNVGSYIMFHAVTGVPFELFSQGAYDGITLWEQIDGGVQFTATRKYLTTVPIVLFLLNTHYTHYAPVAFSVTLVATIINLIAKLPSMHQVRLFDINQKID</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T338</accession>
    <name>A0A9P6T338_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PH domain leucine-rich repeat-containing protein phosphatase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">PHLPP2</name>
        <name evidence="4" type="ORF">BGZ80_003133</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000181">
        <property type="protein sequence ID" value="KAG0021053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T338"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050216">
        <property type="entry name" value="LRR_domain-containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051:SF1">
        <property type="entry name" value="RAS SUPPRESSOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00019">
        <property type="entry name" value="LEURICHRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00364">
        <property type="entry name" value="LRR_BAC"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="34"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="466"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="521"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="610"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="751"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="40"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="466"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="543"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="610"/>
            <end position="625"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0021053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="861" mass="93371" checksum="BDFFEB098416762C" modified="2023-09-13" version="1">MPHQATLRRDTESDISPISLSHFTLADNIHSLSLPPPTTFSPTSPTSNNNSPAPRRSSASDSFGMPMMTKKESSFNIVTLNSNAGTIPNTTDVGDDVMDIESCIDDPILAPLGRHVNKKRYSRRLDKGHIDINVVRPTSPATFIKEQEHEPHSPVTSLILRRRRLDCVQLENYFQNLQPTLDPHTMCTLQNPLLHLTELDLSRNRLESLPTGMTSLMPFLHYLNLSHNQFTEVPMELCKLAHLQVLIMSQNRIEGPFPHQICSSLAQLKTLKLCSNQITSLPHTLARLDKLESLSMGSVYGGNLLTSFPSNCIQYMTALRELDLSHNKICFLPADIGHLHSHLRQLVVSDNKLEAIPKSIGLCKELRNLNLGRNQLTSLPTEIADLKQLDTLDLSENLLCVIPGDVADFLTKTTLLLTGNPFTRGYCDANRNPISEIGGLGINNPSDEERYAAVLKSLSRRAILNAAASSSSSGSHTPTPGSIAAGRESRRHSVVGENSYEMDQDEKLDYHLYYTRHALSSRPPSRAESVVSLNEHGGGGSDNGSANGGSWNDPYGGGTGPSTPRVNVEAVISDIDSFFDYIPSLNISSTVATISSNTTMAEPSIFEPTTPTPTAVTSPTLPSTPQILSPTSVHESVHDQVIGRGSTANSISQPQIATQSQSFFPTLKELAARTVLHIGEPLPIELIPEAVIDYLEPGARPCALCRRPYVKEWVSSVRVKSYQGHPAVARRVRFCSVACWKTAGEQFEAEESRGVTPSVGIPGATTGHLPPVTTRTDCSEVTSGIEGNISLLDSALAGTRVCKGGQTYWPVIGRSEREKRLSRSSSSSSLMSLKSPISAAGSITKANVCSGGCLGGGVCEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T368</accession>
    <name>A0A9P6T368_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Transcription activator GCR1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_004024</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000210">
        <property type="protein sequence ID" value="KAG0020537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T368"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022210">
        <property type="entry name" value="TF_GCR1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12550">
        <property type="entry name" value="GCR1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transcription activator GCR1-like" evidence="2">
        <location>
            <begin position="358"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="250"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="448"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="293"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="461"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0020537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="476" mass="54301" checksum="8873924D0E98CAB8" modified="2023-09-13" version="1">MGGMSVCQYVEFCNGNQINDIVEPNKVVKFLEEKYFTRDKETSIKSNIGYEGIVGRTEHDPLYHPSLAKAEAKEVAARFVEATKRSLDGTNSIKYAVPIGKRTIDSVISALSYEWKLQKLDGRNHFDKPRGEFPRWNGRMTHIRDRVAINLRHQMLLGDENLRHLDLSDCISECVATPLYGTTKTIYSLGFCLSRDKTMANSQKDQRNMDERFAQLHEKMQHNYEKWLEDSRLQSQIAVKAMLASMSSYFSRSPTSPSVQSIGRGGDDTFLSTPSQSNHVSHDMQTIDREGLTSASSPSQTQPSHGDHHGTPESPRGSFEVGAIATISQRQPSMSLQPSFPASPRASQEMVTQKHMAFRFRRDADTVQEIWEEYQRYIAYKNQTRRLGYDSAQMNEYLSEKRFINNRLVIVKEIEHLNAIREITVDQAISQLDHERCTSKKSIAQFQDLSRKRQKGRKTEGNNTIQEATNTSNNTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3B3</accession>
    <name>A0A9P6T3B3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001896</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000145">
        <property type="protein sequence ID" value="KAG0021685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3B3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="278"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="299"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0021685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="648" mass="71626" checksum="8FD51D8E008AA42A" modified="2023-09-13" version="1">MLISRVVIGVQFKKREEMMLREVEEYHIRLKGPPQDSDQDFDLNTASNTRDQSIHEAQASAQTLCTAVSSPQSSTLELAQPNHAGHSVDTTKNSHVKKGDDLTETSPGDLDTHNTSYRRRVAKKSQRPTTIIGQVRSSIFGGISSSGSRPKSVPVFDIDRYEKEILGLGYEQNKHRLYREDLDEFQVHDIFQSECARQENEAEGSGHGSYGDGHEFPISFDSVLPDTFDLNGGYATRRATAVNRCTLTRTQLEEEQREAKYREIVKALRRASSVATGKYPNQTLSGVNNLDMTANPSQDRQRRVSSRDAGGESSAAGFVPRRPELGATSQATKAQFRKSLPALLNPTPLSYKTNPYLFHQPSISDVLSNISSSSSNRSNYGFPSLPMLLIHRELAVAAKEKNRIQNLYYNPVLREAKARAIVWLPSQTERSFWGTHGNEGTEHCKYHAELRQNKAAAPSATDTTESVEDLSSFGLSTSTLAPAEQAHPNGLASYHRGKHQCTCRLYQQVTQAVADAVALADQEIRDLRIVGLTVWLDSRHVIWGQVNEEDGRLGDRVMISTVPHQFVSGSTVKSNIQKQVGDGLLSWLEAEELEDGEDGEIHNDRLRQIGQGAPGIIGGSVGLVMKRPIGSYGKLVGDGEEDNISREC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3E6</accession>
    <name>A0A9P6T3E6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003381</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000189">
        <property type="protein sequence ID" value="KAG0020910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3E6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022234">
        <property type="entry name" value="DUF3759"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12585">
        <property type="entry name" value="DUF3759"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="255"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="266"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0020910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="392" mass="44719" checksum="60E54CE6195A8E98" modified="2023-09-13" version="1">MTPAPEENMIRQAWHSLEEALHLREPVPPPVPPKDEKWLIKTVNLALPQDEPDPSFWDKIVQRIAALHSHTEEEEEQDAVSISVPAEAALRQLGVQADDSEIQAKKDYFERMAVRCKEKFDQDRELPIQGTLTSLDNDEIPSSSDSSQHRHHHQLHHYFRALHHHFHPHHEAAQDGVQGRQNSHMIPKVDPKEMKAAHSIIYHSGKESVDDNDEEDRKLFGPWWGCHSKRSKDEKQLLSRQESEWEIINLPTSKKEKRKSLGEQNGSSTLDTLTTTGNKTNWWKQKPFDSKGLMTLPAKNEQTHDRKATTKRHQAIAAAAAYEAVKEYQARKVRQGKKVTHGEMKAILAGIAMAEAIKILESRHGDDDNDEDRNETVAEAGSVALKLFELLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3H2</accession>
    <name>A0A9P6T3H2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">ATP-binding cassette sub- B member 6, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ABCB6_1</name>
        <name evidence="12" type="ORF">BGZ80_003211</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000184">
        <property type="protein sequence ID" value="KAG0021006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3H2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221:SF654">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="33"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="414"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="445"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="288"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="624"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="186"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="232"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="727"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="895"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="194"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="232"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="895"/>
            <end position="910"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0021006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="947" mass="106131" checksum="A09753F0998D49B9" modified="2023-09-13" version="1">MVDPMDRTFKKRSPISLLYKRAPPPSKGLSNKVIIIVATTVGSLLLILSLALFYYCVHKRRRPSRRGSWLQKFLPTPTDQGRTGQYLQNQGSYETLVSPGPPSEELSLPSNVYYRTRSASTASEKDVAWLLKSDESLEQFQEISLLPEETTVEIKESKPRRSLFSRFASTRVATVAKPDLAKSSSHLGVDLSEHGNQGFTNNTDSIEEENDADHQDKFTEGECLIQESTDCCSSNRDEQNSSPAVSTSSFGQKDYRRPTTFKEFYEHFKHLRSFIWPSNSRKLKVHILLCLGLLVIGRAVNVLVPWQVANVVNALTKVADGSPEGMDESGNPRFVWKEIVVLIMLRMLQGELGVVDTLQELLWIPVGQFNTRALAVKMFEHLLNLSLRFHLNRKTGEVLRIQGYDQRHRGVSSIVTLLSTLIFDILPCMIDIVVASITLTRSFDIYFGIIVGVTMICYIYATILMTNWRTHYRRVSNDLENVVEARAVDSLLNYETIKLFVTEKYETRKYTEAILAYQEAECKSQYTLGILNTTLNFVIQGGLAIGCLLCAERVSQKEMTVSDFVMYYTYLLQLYGPLDKFGYSYKSLQKSFIDMEMMLDLFKEPVEIQDQPEAKPLEMTGREVVFENVSFGYDPQNLKLKSVSFKVPRGKKLALVGPSGGGKSTILRLLSRFYDPTQGRILIDGQDIKNVTQSSLRKNIGIVPQDTGLFNETIGYNIGYGRIAQDRDNGGDGASRLSLSEESTKSDPDIPYYEDLEDSGCIQEAAEAARIHEIVSGFPNGYATHVGERGLLLSGGEKQRVAIARTILKNPPILLLDEATSALDTQTEREIQKSIESISKGRMTLMIAHRLSTVVDADEILVIQNGEIAEHGSHVELMRMGGVYASMWIQQLHEGRAPAESSRSSDKESSNGEEDSDNANSSPGHAPPLFSPHHVITPSSFWMYSPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3H7</accession>
    <name>A0A9P6T3H7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Endonuclease</fullName>
            <ecNumber evidence="10">3.1.30.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">NUC1</name>
        <name evidence="14" type="ORF">BGZ80_000955</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the DNA/RNA non-specific endonuclease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.30.-" evidence="10"/>
    <dbReference type="EMBL" id="JAAAID010000121">
        <property type="protein sequence ID" value="KAG0022142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3H7"/>
    <dbReference type="OrthoDB" id="5418055at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:RNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000014">
        <property type="term" value="F:single-stranded DNA endodeoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006309">
        <property type="term" value="P:apoptotic DNA fragmentation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00091">
        <property type="entry name" value="NUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.570.10">
        <property type="entry name" value="Extracellular Endonuclease, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018524">
        <property type="entry name" value="DNA/RNA_endonuclease_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044929">
        <property type="entry name" value="DNA/RNA_non-sp_Endonuclease_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001604">
        <property type="entry name" value="Endo_G_ENPP1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020821">
        <property type="entry name" value="ENPP1-3/EXOG-like_nuc-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044925">
        <property type="entry name" value="His-Me_finger_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040255">
        <property type="entry name" value="Non-specific_endonuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13966:SF5">
        <property type="entry name" value="ENDONUCLEASE G, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13966">
        <property type="entry name" value="ENDONUCLEASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01223">
        <property type="entry name" value="Endonuclease_NS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00892">
        <property type="entry name" value="Endonuclease_NS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00477">
        <property type="entry name" value="NUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54060">
        <property type="entry name" value="His-Me finger endonucleases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01070">
        <property type="entry name" value="NUCLEASE_NON_SPEC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 10" id="KW-0540">Nuclease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="domain" description="DNA/RNA non-specific endonuclease/pyrophosphatase/phosphodiesterase" evidence="13">
        <location>
            <begin position="95"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="ENPP1-3/EXOG-like endonuclease/phosphodiesterase" evidence="12">
        <location>
            <begin position="96"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="161"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR640255-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR640255-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU366055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0022142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="339" mass="37423" checksum="43C3865530F9023B" modified="2023-09-13" version="1">MVVRNIAIFTGGAVIGAVAAGSYFKSKKESQPAAVTVIQTPDSIKASRSVSAPLPEVPARNGPVVVPRPPPSTSVGNSLKILPHGFPGPVNDLFVREGYIASYNRRLRHPNWVAEHLTTESLKGGDGVGRGNSHFMEDSTVPDLYRAKLTDYVRSGYDRGHMAPAADCKSSQSAMDETFYLSNIAPQVGKGFNREYWAHFENFCRTLTEKYPDVYVVTGPLYLPYQDPANGKFYVKHEVIGDPPNIAVPTHFYKIILTDRGNGDMSVGAFVLPNDVIHDDVPLTKFQVRVEHIEMASGLKFFESLERKLLKDLCKDTTCKIVKHPKSLKNKDQKALPAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T4H0</accession>
    <name>A0A9P6T4H0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">K Homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_006826</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000034">
        <property type="protein sequence ID" value="KAG0023981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008381">
        <property type="term" value="F:mechanosensitive monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00105">
        <property type="entry name" value="KH-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22453">
        <property type="entry name" value="KH-I_MUG60_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.120">
        <property type="entry name" value="Large-conductance mechanosensitive channel, MscL, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056553">
        <property type="entry name" value="KH_Mug60-KHD4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037673">
        <property type="entry name" value="MSC/AndL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036019">
        <property type="entry name" value="MscL_channel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30266:SF2">
        <property type="entry name" value="LARGE-CONDUCTANCE MECHANOSENSITIVE CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30266">
        <property type="entry name" value="MECHANOSENSITIVE CHANNEL MSCL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24563">
        <property type="entry name" value="KH_Mug60-KHD4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01741">
        <property type="entry name" value="MscL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81330">
        <property type="entry name" value="Gated mechanosensitive channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="K Homology" evidence="7">
        <location>
            <begin position="194"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="7">
        <location>
            <begin position="424"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="7">
        <location>
            <begin position="492"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="7">
        <location>
            <begin position="577"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="36"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="690"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="848"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="972"/>
            <end position="1026"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1039"/>
            <end position="1106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1118"/>
            <end position="1165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1203"/>
            <end position="1246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1418"/>
            <end position="1483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="36"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="868"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="887"/>
            <end position="909"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="939"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="973"/>
            <end position="988"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="989"/>
            <end position="1018"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="1042"/>
            <end position="1056"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1057"/>
            <end position="1093"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1118"/>
            <end position="1134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="1141"/>
            <end position="1151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1207"/>
            <end position="1222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1437"/>
            <end position="1450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1455"/>
            <end position="1467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0023981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1666" mass="179841" checksum="54E294DFF043AD36" modified="2023-09-13" version="1">MGMRTMGRTIEERLSISISKDLISLENAATLQEHGNIQGQPSALSASPTASIPGLTLGATKSGGKCETDTDTQSRYLPSPPADKVSQDDITQNALHAQPSSNSDEKLSSPTSTTFAQSFTVLPQFKAAVDEISATTRTTITLLSNNAHILSSGRTITAGLGRQNMVELQVTGMWENAEAARMLLLVAIDTLKPGVVSDKLTVELKFQNMIGGRKRQSLQDLMSKTRTSIYLTSPLVQTANKSGIPVDSRYNEIYITGESKQVAAAKDALSRAYSRAQTSSLSCTRQVNIATRKLDWMLLNHREKLRSIMIDNATFIAFPPLGGTHPTISVYGESSVNVERTIRTVMQLSCHFHSGSITMRDSAISMHLPQSLSSFANICKSVSQASGSEVEYRNNGFLVFGSEIQIRMAMQYLTEADIVKSLPSEFKFSVELANEHREFISGKKNGKINRIMKATGAKIKFDQCNEYNFYVDLSSGIAMKAMEALVLLQEELPAEISFFVPETYHKRIIGVGGKNIQRIMKKYGVYVKFSNSEEFATLGGYFDNLDNVVARTPSKNSINLENLKQAVMELVSAKDKDFVSHRLLIPKQLHLSLMSEHSAALRDIHDATNSTVLFTAREAGSDIVTISGPESLIQQAVEMLLSMVKEQYVIPIKYSAALDNVLELPEFKSEVVDAMKQAWSITLVLPKAKSSEPRNKGADNGGQSKESGEGRAPSTNESSLAKPRDDCAFIFEYTRNKEEYLKNAKDLLIKFLVKHNIEVNEHEIEIPRPRSSSFGEPFANLHNRIASSGANCFADNQSYGPSDYVLFDNTAPAFDSAPGNTGVIGGGSLVTSDIRALFTPSAPSSFIPSLDTSPSRWTDHSRHLSAYSGSPSTHSPGTSTLGASFGVGSTSNIGQNPGNSSAFARTTPSPVDPWAPSKHQQRQSQTSASYLGPIGDLRSTPSGYYSPGGYSQSPHTSMLASDVAFNKALAFQSSGSNSSGNRYSGGNSPVQSGATNLGSFGNPTSRQGSPQHTPTQRPSSGSSSNRNSMQFLEEKMLAGSTFGPGYGPSLNSGGGRSSHQQHLGYQLSQQQQSQYVTQTQHQSLHSYPQQQQQHQHHQHHGISGPTYASHLQLQNSFSYPHQRQRHSSQNSAASHHTMGLGHIGGGPGSAGGSVNSDEVSTEDDSDEVFDEMRNRQRMQSAPAQMFQQSQLLQQSFHTGGFGGGYEGYSSHNSSSSSLLNRRGSGGSTHSIGFQQQQQQQQQIYSQKSLDYSSHLSNGSLDLYGQNALASAMEKACLNSQTESDMNAVGGRSSQGRFGQNRHTIGVANNVNSTLPGTATGSRFEGDHGFFSSGFGGIIGEEAHGYGQGNGLVNGLGHPIGSAFDTHSQALGHQSFSSTFGNFAGSVDGKLFSSESNGRTVKSVNSNLSASAAPFYMDPSLHHGQLDQTSLGQSLGHRHNDSKQQGAEDVRILTVSPSAGSSSSSNAAHGRNDYRHGSQDATISADELAPSVDGIRYRTNTSSGIDEKMALMNHQQPDQSDIDGTQQQAGKGEHHHHLECFHAPGEHCSLPDMMQPLVSPLHHAAVENVVIKVLDSADVTQKTIFYFWDEWKLFVNRGNVIDLGIGVVIGGAFSDIIDSFVADILTPPLSLWAAGANLENSFFVLRQGRTPGKVYATYQEAQADGAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T4M0</accession>
    <name>A0A9P6T4M0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Skg3/CAF120-like PH-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_010830</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000008">
        <property type="protein sequence ID" value="KAG0024673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T4M0"/>
    <dbReference type="OrthoDB" id="5563754at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058155">
        <property type="entry name" value="Skg3/CAF120-like_PH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25381">
        <property type="entry name" value="PH_26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Skg3/CAF120-like PH-like" evidence="2">
        <location>
            <begin position="399"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="683"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="751"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="870"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="751"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="886"/>
            <end position="899"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0024673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="921" mass="99445" checksum="E716BF2B54F0DA4C" modified="2023-09-13" version="1">MATADVQHEWSSKDAMSRDNDRIDPKSSLLPALPLDGEVSKRYVDSDVSGVETKIEGLGINTPQSISPIHTSRSSTGVSYPSPPPVDPHQSTSPLNATLFTEQSSGGAKMRGAKLPAPLQTHALESRVGPLSVRTPSSATFAQSPTSMCDPSVGPYPTQSHQQPWMSGCSASPKHGPLLTPRNSSPAIHPHQTSSYGGSSNSLPLPGTLTPATSSRKNSAASLNAPPRASPGFRGAPLGQTSDTESVLKQFDVYFGKVYLKGHLQKKNDLGVEGFKLQGQQWAAYSAELIGPKLRLRPMNNPNGDVEEMNMEEAIVEMQDGSNGGTFTVNWMGANRVVFQPVQQLSLGNPEVGSKCQDWVCAIRLSCYECSRLQEIYTSTLLRRPKFRDQVAATIEGPIKYEGMLRVRFWAGDDWQRLYVVVSDQRGDEIPKKKQGKVLQAAPVRGQIHFYESSKSKRPFISMYNVSQAYAVCPSRSTLSASKDNKIDEEGSLTIKLEGDVVMQRENLASPKKGFFSSPTPPSLVARDLQSLLPTGRSMFAMLQVPNAIERTKFLLGTSEAFRIYGKPGPLLFDSPTDPAAMNFGCMASSLLQQELLIGLDAVLHLPQKGESLADVKFSFGEVLRKRLIAENPSAQRGFPNPYARRHSSVPHSYYPSDGLGPPSPMMAMAMRARANSAGFLVPQPSPGIHPTHMTPWVGGSPHSPQLGPYSATNSPRQGPLHSSHYGHYQNRSLYAPSSASTDENDANLVTDEEGEDDEYPDTPEEDNDGYTTPYRSRAGSLMAPPGPGYHQVRQGSIGALSVQSGRSGRSGSFTSAYGVQLIAPEAPKKTVLELPSLHSFSEDFAVKGDDSNQKQKKLTAVVYPTQIVVPKNKKRKDSVNGETGGSKSAASMNSSTAPTAGDAHSPSVVIDRNIPEGQEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T514</accession>
    <name>A0A9P6T514_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">LYC1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003703</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000002">
        <property type="protein sequence ID" value="KAG0024844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T514"/>
    <dbReference type="OrthoDB" id="2020070at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055100">
        <property type="entry name" value="GNAT_LYC1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053013">
        <property type="entry name" value="LAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34815">
        <property type="entry name" value="LYSINE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34815:SF2">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22998">
        <property type="entry name" value="GNAT_LYC1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LYC1 C-terminal" evidence="1">
        <location>
            <begin position="190"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF22998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0024844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="376" mass="42857" checksum="35CC8A1285B7BB4B" modified="2023-09-13" version="1">MTTTNSTTSETKGTSTAPIVHGDIHLIRATSQEIIQRTWTNNQQEWGKDFGAETYYARERFLASQDFASNGKQKFWVLVPRTFDPEHPDLDLILSAVETFERPGIIATKEQGLRDVLSVSIASVFTPAHYRGHGYASLMMRLLWKEIQKMDKVEFTFLYSDVGPVFYSRIGWIAKRSDEIVIPTSHTIANPTSSSDVVLQNVTEHQLLELVEKDAKWLRESLQTRVESSDRDDVFVAVIPEPTCIAWLNARSRFTAQNLKVSQDGPTILGVQDSQTNSFVLWFHDFAHHQLYIIRWRMDPKAGVETTRALLQAAQAEAQMWKLPKIVIWNPDQSLVDTLGLDISKRDESISSIGFVSAEYDSKNIEWVLNEKYGWC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MCE2</accession>
    <name>A0A9P6MCE2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_008660</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004773">
        <property type="protein sequence ID" value="KAF9992198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MCE2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9992198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="84" mass="9372" checksum="12878E71401D2FBD" modified="2023-09-13" version="1" fragment="single">MDHLPYTNILRSRDRSSPWEHLELPKLPRAILRKHKVNAASMLAHPSRGPMLALPVGPYVGTPRRALCWLSPSGLMLALPVEAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MCE9</accession>
    <name>A0A9P6MCE9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_008887</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004995">
        <property type="protein sequence ID" value="KAF9991773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MCE9"/>
    <dbReference type="OrthoDB" id="10500759at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9991773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="100" mass="10959" checksum="4436E2B3571C3E01" modified="2023-09-13" version="1" fragment="single">MSSEEPITTEEYVSPFAGVVFGPQRRKDKNAAQLLKFLGEIPKLLEAGPFSTFEVISKPIDSHGPELIDVANLHEFPGVPSNRVLLQANKLIGNKEDVSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MCN1</accession>
    <name>A0A9P6MCN1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008631</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004736">
        <property type="protein sequence ID" value="KAF9992270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MCN1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052766">
        <property type="entry name" value="S41A_metabolite_peptidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37049">
        <property type="entry name" value="PEPTIDASE S41 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37049:SF4">
        <property type="entry name" value="RHODANESE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040219707" description="Secreted protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9992270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="157" mass="17417" checksum="014FD8A04A7AFA00" modified="2023-09-13" version="1" fragment="single">MLNILKTLILSTGLAALVRSAPVPVSQDPCAIIARASQNLTVQHVSDCYKSIEYNSVEAKATLASLYTLYNDFWIFRDSAMTPNQALPFTNPPVDIIAGLAKINQTAYTRDFDFHSDLTYLIKSLNDAHCTYMPNCYNSYVFEQPIGLYAPVVNGVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ME01</accession>
    <name>A0A9P6ME01_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_007773</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004031">
        <property type="protein sequence ID" value="KAF9994597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ME01"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF120">
        <property type="entry name" value="KRUPPEL-LIKE FACTOR 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13912">
        <property type="entry name" value="zf-C2H2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="307"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="335"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="364"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="151"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="265"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="165"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9994597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="394" mass="43153" checksum="9CC6F7A4509C4659" modified="2023-09-13" version="1" fragment="single">LGSDPRDFYVDDEKDLASAGPGAKQPRDGMRLNRILNGSEQQQQQYQGYPYQDDSFRSVPVSTFPVSPVASLSPMTSSDGSPVPAGMAAPTLATMSSPMSPMTSFPTMSQPNLIFEDVMPYSYNITQYQTQAYPFKHAGNARPMDQSVFAAESAQAHSPQAHHYSSQSPDPSGGSPTILAFPQRTMNSLVDHQYAVSDSPPSSFYHGHQMPSPYSVGSHSPISTGPYSSAYGTPETANAFTPTPPTTPHYGYAGAAPLYGDNFALQPHTASRSNRPATFRTRKAPYERSARTSEQGLNGVTPPPRRFQCPECDKAFPTKGELASHSRCHLKVPAFLCGICGRPFKRRTDYVRHVRNVHEEVGRYGCSQCGERFGRLDKLKRHDKRGCGNDKDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MEG7</accession>
    <name>A0A9P6MEG7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_007610</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003923">
        <property type="protein sequence ID" value="KAF9995096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MEG7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9995096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="391" mass="43637" checksum="387D28FA8EE2E749" modified="2023-09-13" version="1" fragment="single">MTKAHQAATLTVGLVAANGEILGGLTEDEKTAIGKLIQDCVNVGNFVKREVHITLASYIKNKGNKGLENIRRALLKYPDDIEGDEDTEFGCADSAGFFRSLLVNLCNGTRPRGQRHKETLGSIMNLYFKKFPKNEGKSCIKETAIIPMVLFPSIANAIAVQYKRYFQETRAGKNSRLTLAPVRNSFILLTEREFLLMLWKDPTMNEHLRNKLRMKSDGESDVSNVLKGHALGSIINMFLTSVGLGPITGSKSGYQRQTKTMTVGEMKEHLKELYKGPSGSQSDLPENSSDRYVLRGSFRTNGVQLHLNAINTRVIADRKYSRSENRHKPDMKLMHDPCEGYDSYLREVQNVFPDRNAVLSVFGDNSTDKNRPWADIDVLALDLGEAFTVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MFM3</accession>
    <name>A0A9P6MFM3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003536">
        <property type="protein sequence ID" value="KAF9997292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MFM3"/>
    <dbReference type="OrthoDB" id="2306559at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9997292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="96" mass="10843" checksum="42061E36A837F31C" modified="2023-09-13" version="1">MSFHNVKLESSSTGSSFPADFAKPVPLAVVSLDNDEAFGYLKRVIVTPAVYPRLVEFLHFDIQSTGQKSHCVNTTFWPSQCYVLIRQSDSPRPYQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MJX9</accession>
    <name>A0A9P6MJX9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Crinkler effector protein N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_005401</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Host cell</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002665">
        <property type="protein sequence ID" value="KAG0005722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MJX9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043657">
        <property type="term" value="C:host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045379">
        <property type="entry name" value="Crinkler_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20147">
        <property type="entry name" value="Crinkler"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Crinkler effector protein N-terminal" evidence="4">
        <location>
            <begin position="8"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF20147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0005722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="107" mass="12126" checksum="44373EE3FF082F9F" modified="2023-09-13" version="1" fragment="single">MSGNSLKLLRIVDEEASDFYVEIDDSKTVGDLKDAIKNKKPNDLRDIDADKLSIWRIAISNHDSETPIFLDSRSEKKKKLSATSKLSIVFDETFPEDTIRVIVEKPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MLZ5</accession>
    <name>A0A9P6MLZ5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_004728</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002380">
        <property type="protein sequence ID" value="KAG0007378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MLZ5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0007378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="55" mass="5524" checksum="2E522087DC8DFD68" modified="2023-09-13" version="1" fragment="single">MSTGTIKPKVLIVGAGIGGLTLGAILEKANIPYEIFEKASTLKPLGSAISIGPSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMG6</accession>
    <name>A0A9P6MMG6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_004344</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002222">
        <property type="protein sequence ID" value="KAG0007705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMG6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050491">
        <property type="entry name" value="AmpC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021860">
        <property type="entry name" value="Peptidase_S12_Pab87-rel_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46825:SF15">
        <property type="entry name" value="BETA-LACTAMASE-RELATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46825">
        <property type="entry name" value="D-ALANYL-D-ALANINE-CARBOXYPEPTIDASE/ENDOPEPTIDASE AMPH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11954">
        <property type="entry name" value="DUF3471"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase-related" evidence="2">
        <location>
            <begin position="6"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S12 Pab87-related C-terminal" evidence="3">
        <location>
            <begin position="128"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF11954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0007705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="231" mass="26324" checksum="0556C917105BB209" modified="2023-09-13" version="1">MDWDITPVKSYLPVFELMDPVLTSQLAMVDLLSHRTNLPNAGELAWYRSTAEIRDLVKKLRHVNMSSKLGSKCQYSGVMYGVAGEAAANVAGISYEKLVETKVLEPLKLKNTGFKPMKQGLEGLLPKRIPKNLASQDLKAFEGEYTNPVLGDMTVRVEIDENTEKETLLFKMGPFDRKLEYYHFDSFVGIIKDWNMTATDLTTFRNGRDGKVEGLRFFEEEFKRKNERTSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMH0</accession>
    <name>A0A9P6MMH0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tethering factor for nuclear proteasome STS1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">STS1</name>
        <name evidence="5" type="ORF">BGZ80_004097</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Involved in ubiquitin-mediated protein degradation. Regulatory factor in the ubiquitin/proteasome pathway that controls the turnover of proteasome substrates. Targets proteasomes to the nucleus and facilitates the degradation of nuclear proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Binds the proteasome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the cut8/STS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002129">
        <property type="protein sequence ID" value="KAG0007900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMH0"/>
    <dbReference type="OrthoDB" id="10061064at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031965">
        <property type="term" value="C:nuclear membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070628">
        <property type="term" value="F:proteasome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071630">
        <property type="term" value="P:nuclear protein quality control by the ubiquitin-proteasome system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031144">
        <property type="term" value="P:proteasome localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1590">
        <property type="entry name" value="Tethering factor for nuclear proteasome Cut8/Sts1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013868">
        <property type="entry name" value="Cut8/Sts1_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038422">
        <property type="entry name" value="Cut8/Sts1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28032">
        <property type="entry name" value="FI02826P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28032:SF1">
        <property type="entry name" value="FI02826P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08559">
        <property type="entry name" value="Cut8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0647">Proteasome</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="18"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU368013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0007900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="258" mass="28969" checksum="7C742512F21B4ABD" modified="2023-09-13" version="1">MSDPLAMLKRKQSEDIDSPMPSSGPASPSDSSDSSSMERAKIKRVRTTTEMVSKKKSVSKLIATLSSSQLINLVGTLVDNHPSLAEEIANLVPRPTVASVQPLLTSLETKLQEAFPYTKWGPGRDDYSFNRVKPALEELVETLTDYTNHFTSPPEFPTTSFSFLHIATEFCHRLPNWDSAANNELKSNLYKSLEEYWIKAIRDASSKLEEGKIYGHMTVQEWAKNLQQHQEKSHGMFSSAIEEFKSKLGWIIGLQTQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMS5</accession>
    <name>A0A9P6MMS5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_004069</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002118">
        <property type="protein sequence ID" value="KAG0007924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMS5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0007924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="552" mass="62442" checksum="689545B9B58A913D" modified="2023-09-13" version="1">MEGVQYRSSKVYVASGSSTFNILVLGDKGSGKSALIEAIKGYDNQDISHLEIPSYTPTTEAASTIITTSLPRFSVFRNDYGDYEYNGKQSSTRLDNDTVRRYLSLTDDEYNLRKSRLHIQKDQLPDNSYNFSFRLIDTPGLDFTMDGSKQQRSNQESGAFVSKALPAILNQLGPTCAIHLVLLVVPDVIDYADSIEFYRSILPELGSNTVFAYRGTKNDIATSIEIQLRNKLLDGNNHADPPHILIDKLFIENDPIRACLARNDIRRILELALLNEPVLMQPKKPSFIKDLDSFLQDRYSEVLKTIHHAVATTDESSPFHAIMKLAKNQCDDEARNEIALSSPMKLIFSKRFENSWDASLTATKSMTVDMESADGEITQIDILKHNVEIVNQDGGKGTRRFSLVFRWTSASYGVLDVRIYTGNTIHHSIDAWKGTTEANQKKMTEAVQNAVSKSKNPSNQQKLITEFLKRYRHYNIMHRRASSSVIHPDAAQILSVCNIGQSKPIDLFECVERLEKAYLEAVNASLEINLTMYRFREHLLNRRAEAPWTKIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMX8</accession>
    <name>A0A9P6MMX8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">GH18 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_003928</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1-&gt;4)-beta-linkages in chitin and chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.14"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the glycosyl hydrolase 18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002071">
        <property type="protein sequence ID" value="KAG0008042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMX8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008843">
        <property type="term" value="F:endochitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12215">
        <property type="entry name" value="ChiC_BD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.10.20">
        <property type="entry name" value="Carbohydrate-binding module superfamily 5/12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003610">
        <property type="entry name" value="CBM5/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036573">
        <property type="entry name" value="CBM_sf_5/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050314">
        <property type="entry name" value="Glycosyl_Hydrlase_18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177:SF392">
        <property type="entry name" value="HAP41P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02839">
        <property type="entry name" value="CBM_5_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00495">
        <property type="entry name" value="ChtBD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51055">
        <property type="entry name" value="Carbohydrate binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54556">
        <property type="entry name" value="Chitinase insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3" id="KW-0146">Chitin degradation</keyword>
    <keyword evidence="5 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040110031" description="GH18 domain-containing protein" evidence="9">
        <location>
            <begin position="21"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="10">
        <location>
            <begin position="31"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0008042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="511" mass="55179" checksum="5FE36EABA842A57D" modified="2023-09-13" version="1">MKITLVSLATVAFAIVSVSAVPIKKRASDNKVVVGYWVPWGDVPVSAVDFTKYTHINYGFGTLLKSAANPTDINFDRYYDGDNMQQLVQKGNQYGVPILMSLGGWTGSETFSTVVADANLRKTFINNAMVFVRKNTNGADATTPNGWDMDGIDFDWEYPGRQGADNNAVSSADSANYLLLLKELRAQLDLEFPNNHKLITAAVRVQPFDGPNGSPLSNVAAYAAYFDWVSIMAYDIYGSWSETTGPVAPLGTPPSPNAPYSVTQAVQSWTAAGWPEDQLVVGTAFYGYSFTTTVNMNTQSPVTQYVPYVSGSNTASSDACNGLYTTGATWSWKSLRSCILTAGPTTPASGWTRYWDSNTQTPWVFRASDKTFISYDDIESITAKVNFVKQKNLRGVMLWEIDYDINGELIGALNLVHSGSTTTTTTASPTKTTATVTTTTTVATKTTTTVTPTTTSGSSICSGVPAWSSSTTYATSGTKVTYNGHLWTNQWWTQNETPGAAWGAWADGGAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MND2</accession>
    <name>A0A9P6MND2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_004176</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002157">
        <property type="protein sequence ID" value="KAG0007831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MND2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="237"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="159"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0007831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="398" mass="40664" checksum="4B40FD92514E8B4B" modified="2023-09-13" version="1">MRLSLFSRSSSSTTDLRPSSSSTLFANKRMSLSVTILVTLLSLSFSPSITEVSANPATAGFCGDCQTFANAIAPCGVTFGPTDIQINGTYTPPQAAANCICSSIMQSVLWTCARCELLAGYNSHSDPPTKYHTTCISWGATITQWNAPYTGVVADGTTTPMTTNNSTTTGGTSTTGAATTGAATSGSIGATTGATGTSGTSGGTSSGSSALAGTTDVSTGNSTTTDASESSGPNGTAIGISLGIIGFACAGGALAMFMMKRSRRRHEPLELDGAYVGLDDSWEREKPARVQSPPMIPAPAPITARGPARGSPFENRPGGGGSVVGGYDGQYDQYDHNYSSQYQGGNGGYGYQGYGDQGYGEQGYGDQGYGGHDYGYEHTVPTGVYHGKAGSEVGGQYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNG5</accession>
    <name>A0A9P6MNG5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_003891</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002059">
        <property type="protein sequence ID" value="KAG0008064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNG5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090575">
        <property type="term" value="C:RNA polymerase II transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14810">
        <property type="entry name" value="bZIP_u1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050936">
        <property type="entry name" value="AP-1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621:SF10">
        <property type="entry name" value="BZIP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621">
        <property type="entry name" value="TRANSCRIPTION FACTOR KAPC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00170">
        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="5">
        <location>
            <begin position="174"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="34"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="106"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="192"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="50"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="106"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="170"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0008064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="577" mass="65403" checksum="B6D1A0C0466C4EF0" modified="2023-09-13" version="1">MNSSNGITETNVEDMSNAELFQYLFKAELGADLPEQLSPDMPPSMPSQPTLSNQADPSILDNSSLSLVQTVTATASSSSPSSSNLMPPDEISIWIQRFQHLQQLRQLQGSHNQQQQEPGSSSQQLASGAKNVIYPSPPINDDMLVDSDSDDNPSREDNNVSDPLKPSASELKKMTSKERRQLRNKLSARNFRVRRKEYISSLENQVKEARREASELQKKLAQSELNCQILRQELETTRLSQTLFNDGRMSKEHANLLASLLNPNTESFPTTTSSDSALSSIQLQQQQQKELMDSINDNNMTILNNSLTIAQPPSTASNMNVSHGSLQPFVPFDGNWELIINRAEMVVDPTLDPKDVQSKEAVYHDLLARYEAAKYEAEVDEQMRTELKAYHDQKLSQTYIVMPKEDAMFSASNKASQDTLVLQTMVYMMMIHLTRSLFEAATLSKTQLVNVYQTMDEPLRSKMGQEQQQERPPCKFREWRESWMRRRWPSFYNNRQRVCELLKNGLCPSTSTSSEVDIDETVRKMEEGVKDKTVEPQLGFFCVWLRGCINSWISCHQYVTSEVLKAMLPESSQDATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNW2</accession>
    <name>A0A9P6MNW2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003532</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001939">
        <property type="protein sequence ID" value="KAG0008367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNW2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0008367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="335" mass="37297" checksum="A7E2527EE3E71D2A" modified="2023-09-13" version="1" fragment="single">MHRFDSGANSPGIENRGTIEQFMQRESNRPQLGSSVLPQHYSYFRSQPQTHTPNGTTLAKTTGNNPATSASEGYICNECVQEESEEDDYEEERYDDSEYVDDEVTSLLNNAFLQMGKTPTMDDAPHLHKRDGINSEEDGNDDASIDVVIGDQRDKILRKAVNPTDELDLDFGSDEYDSHRRRNSWSTASTTSQTPFAPVSKKKKAGTAPRVKGRKRTKECTHRHNHHVADKNHHAQKHSHAPLTNGINTLPSYGAVPSSAAGAGQHSSTLSQPSTLRSDYANHLRRTSFPRLRAQSTIFSRHDSLDHTVADDREHADLTQIGIQTALTIAVHKFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MP06</accession>
    <name>A0A9P6MP06_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_002957</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001757">
        <property type="protein sequence ID" value="KAG0008879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MP06"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="101"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="141"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0008879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="294" mass="32253" checksum="920099660CF7ECBC" modified="2023-09-13" version="1">MPKNLTLEEKALIVGMLFGDKTGKEIADKFGVPLKLLIASEKIIKSLRKPEERSIALALYADYVYIVSAPALSTKAPIVVIRRISLIAEPKQKSNSLSPPSINTANSSNSGGSSYSNKNGSNVLARRSLQSLSEGIPEIQSSGSRSNSGSRARRSSMTALEYRSMNSTNRSHHGHHHHLQPHHTDRYDWVYITSDLPRGRPFFNSSTNVNSSSSSLDMHKTSTASSTASSISIVTAITLHSNYDQKDTAACKPQKSSKLRRIGRKIRSIFSCKSNQESTIPQCMRAEQDSNMDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPP1</accession>
    <name>A0A9P6MPP1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UBX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_003047</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001785">
        <property type="protein sequence ID" value="KAG0008796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPP1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02958">
        <property type="entry name" value="UAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01767">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006577">
        <property type="entry name" value="UAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001012">
        <property type="entry name" value="UBX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050730">
        <property type="entry name" value="UBX_domain-protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23322">
        <property type="entry name" value="FAS-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23322:SF6">
        <property type="entry name" value="UBX DOMAIN-CONTAINING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13899">
        <property type="entry name" value="Thioredoxin_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00789">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00594">
        <property type="entry name" value="UAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00166">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50033">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBX" evidence="2">
        <location>
            <begin position="257"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0008796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="325" mass="36243" checksum="67C2DC8622DE60A4" modified="2023-09-13" version="1">MFLGPRQAPSVFLPPDSSSLARDAFRDFAAEAATLGGNTSPKTSRLADLFKAPLDMMARGDFEQSRNVAKNETKWLMVNIQEAGVFACQVLNRDLWSDASVKEIVKENFIFLQFYSDSVEGKKYAAYYPLKTFPHIAIIDPRTAERVHVWSKAIDPVDFLSDVSEFLDRHSLTDSASKPSQPKKKKLVKDVSDMTEEEQLHVAMMASMGGDASSPINVGDDLDDTNFESKPEEAPPVEEEVSVFDSIKPIRHEEPTDQATSTRIGFRLSDGSRLMHRFSKNAPVRALFEFIKAELVFIGKPLLDDIDKTLSEAGVENAQVMVQFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQN2</accession>
    <name>A0A9P6MQN2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ras GEF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_001785</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001415">
        <property type="protein sequence ID" value="KAG0010103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10254377at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007265">
        <property type="term" value="P:Ras protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06224">
        <property type="entry name" value="REM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.840.10">
        <property type="entry name" value="Ras guanine-nucleotide exchange factors catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.870.10">
        <property type="entry name" value="Son of sevenless (SoS) protein Chain: S domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008937">
        <property type="entry name" value="Ras-like_GEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000651">
        <property type="entry name" value="Ras-like_Gua-exchang_fac_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023578">
        <property type="entry name" value="Ras_GEF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001895">
        <property type="entry name" value="RASGEF_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036964">
        <property type="entry name" value="RASGEF_cat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113">
        <property type="entry name" value="GUANINE NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113:SF363">
        <property type="entry name" value="PROTEIN SON OF SEVENLESS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00617">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00618">
        <property type="entry name" value="RasGEF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00147">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00229">
        <property type="entry name" value="RasGEFN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48366">
        <property type="entry name" value="Ras GEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50009">
        <property type="entry name" value="RASGEF_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50212">
        <property type="entry name" value="RASGEF_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-terminal Ras-GEF" evidence="5">
        <location>
            <begin position="245"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-GEF" evidence="4">
        <location>
            <begin position="1252"/>
            <end position="1635"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="88"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="212"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="446"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="710"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="781"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="894"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1111"/>
            <end position="1136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1285"/>
            <end position="1305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1433"/>
            <end position="1496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1508"/>
            <end position="1535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="49"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="115"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="138"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="167"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="212"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="466"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="504"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="543"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="569"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="657"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="724"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="781"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1287"/>
            <end position="1297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1475"/>
            <end position="1496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0010103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1641" mass="183236" checksum="8B17CB954D4D86CA" modified="2023-09-13" version="1">MTTNSIHNIPLFSQSQEQPSTTASVNDQLINSASRINMDEQGYHWDSPATPQDNLSNVPATMPNHAPSIFDDIQSDDNESYIIWSSSSASSLKKPTSAPTTTATPTLQHQTIPRPANSAPAHSPSSASAIAAATTSTQHPLSLPSATSKEVLPPSIAQGGSATKRWSAKETFKSKDKGKGVPDHDPATRQHSQDILNSRFAGAVRSMDAAMSTGQAKLSKSASNSEPTAEAVAAGGSPKKVTDDPDRVIMAATVEKLVEKLTSEIDYTFLTDFFLIYRLFIAPTALLNLFILRFNWALIDDSPQRQIVRIRTFVALRHWILNYFGYDFMRSKELRQKLNTHLRSLSKHPLVVESQRDQRIIRELRRYVQSLKKIYYRNITQQKLERQARKLGERQARRLQARRGSSLACRESSVEWSGILVSESDSQRPLPSRRSSTVAQEILNRVGNASESLTEELTVEFRSSEQSEEDDSEMGDSMDIEDNFEPSSGNSLYDSEEDSNYSTPEDRDPEREYTTDDDELYEDGQRGDITDSESESLASSQEDNSHGRIRIRDAAFTKECRLPSPPFSPRSQKFQQERSASLRSQQPPQSIASSMASRARNRGKRPPLPDFEGAESNSAANLDPPSPSFFHSMGANRRSRTKTKSQPLSIVMPALSPYTQTGSPLSNRGSIRSIEPYINPPPRSIQSIEKKKTWSKYMSATVGRLSKMKKVFSSSSRKGHRHSLPSSSIHSGTNTSKRTASGITHSSRYWQGNRSDPEGDKFSHYLLGSCTGMNMLISSSEDRHLSTDRRFTSERDHQREEVRSDWSSDDDYSQYEMTRRSSRQVPSQDELALEEPEAMDPQLLEARLEQAQYLPYVELNPGHVEISQPTACRGYELANARDDTIFDVCSECEREKSGPRPTNPCPTNQRDTVLTLGDKAPEGSNREDNLNVATQKRDPTFRSTWATYSPTNPSKAYHSPSQIIRKQWSHGNIDDRFVQKMSRCDQDLPQSQMDGEDQEPQYVSAPQEATTFHSLRSDVHNNPSVSNPTTIYEQAVQNNDLPRRHPSDTQHMDWDQTEAAVEETSIPNPHSVQGPCYVSLHPLQPEGEGDQDIGFNTTTSTPLDELTEAQSIKPFDSAPRVNSNIQPPPPAHYRSQPLTLVRPSLPKARSKSQPHLLNSFSDPEISAQSTNKATLKLEGRCSHVNSLQSSRARQTHATPPFMSRENSYFQECSRPGHISRQPGMDATLHQPLEPVSFSMKEPRKLPMVLRYRSELIAQQLCLIERELLNQIQWYELVDAGWAKKPASTDQPKVTTAAETEASDKETVGVASEVTRRTVRRDESQGIKKLVARFNLSCQWVASEIVKTRDLDMRVKVVEKFIRIAHTCYNHSNFSSLIQLMLGLQAPSVSRLNQTWDRVRAQEMRIMRDLVEFTLPLRNWKHLRDAMKNIADEWGGSGSEATPSSPPATEKPSSGSGVAFFNRRSSKSMAGAFASMTPSRRPSASQPSDSNTAATSTLPSSFFSNLQASGKAPSVPFSPPTMSTSAKSKDKEKSGRQGGCIPFLGLYLSDLVFNSELPSYIEPITHASSSGSENGKLVNIHKHRTTATIIKRVLAFRAMTARYPFQPEPEVHELLMAIVGLEPAEQTRQSYLCEERASDTAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQZ1</accession>
    <name>A0A9P6MQZ1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">cAMP-dependent protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BGZ80_001825</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.11"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.11" evidence="1"/>
    <dbReference type="EMBL" id="JAAAID010001425">
        <property type="protein sequence ID" value="KAG0010061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQZ1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005952">
        <property type="term" value="C:cAMP-dependent protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004691">
        <property type="term" value="F:cAMP-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd05580">
        <property type="entry name" value="STKc_PKA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000005">
        <property type="entry name" value="cAMP-dependent protein kinase catalytic subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000005">
        <property type="entry name" value="cAMP-dependent protein kinase catalytic subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353:SF37">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT PRKX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="97"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="12">
        <location>
            <begin position="352"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="367"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="457"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="505"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="547"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="571"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0010061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="614" mass="70491" checksum="88C73F673F019A04" modified="2023-09-13" version="1">MSNGHGNFEPGGMAMASLSPLDENALRNEQFQEHQLRIQEKFRAQHQHQMDFGQATHPHDPVPKDGTQPYYTSQGKYIIPTASPCYNSRPQCSLADFELLETLGTGTFGRVYLTRFRQDNSYYAMKVLKKTEVVRLKQVEHINSEKQILAQVHFPFIVNLFTTFQDDRNLYMLLEYVIGGELFSHLRKAGRFTNDMTRFYAAEIVLAIEYLHSRDIIYRDLKPENLLLDSKGHIKITDFGFAKIVEDRTWTLCGTPEYLAPEIIQSKGHGKAVDWWALGILIFEMLAGYPPFFDDNPFGIYEKILAGRIYFPAYIDPAAKDLIKKLLTSDITKRLGNLKDGSDDIKNHKWFRGVDWEGLYNRTVKAPIEPPYVHPGDTGNFEKYPEVTDDDATQGDPYSGAGYGFQSSLSQPGLIGQEQGFSQDQQQQYHYQQQQYQLQQQHQQEQQQYQQEQQQHQQEQQQQQHHHQQYQLQQQQQQQQKRLEQEQEQEQERQRYYLQTQQGVQTPFDQSPGPSPPTSLGRSLSKRLRVDTDDGEAISSAFHLGSQNDQMSPWEEMPSGISGNGVWAASLASQSTQHSPTQFLNGPDPKRRRGDREDWPLGGADANGSAMELT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRD6</accession>
    <name>A0A9P6MRD6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Terpene synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_001350</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001302">
        <property type="protein sequence ID" value="KAG0010600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRD6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0010600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="272" mass="31516" checksum="4FC981B9CB2A7037" modified="2023-09-13" version="1">MTSISPLVEALNKSKLAIATDKVTKAMEELKQYWDELGLNHFEQVMDYTNCLLLYCEQLPHPEKSYIVVAAEFSHYLAIDKFLFADDDSVVDRIHAKYLGFLSRYLGEKEIEYYNHCFKTWVSTCHEEAVLKVSLPKMTIPVARYSMWADWRWVNIGMAPYMRMILMINFPDEDLHSAIAQSSIMYISMQTALLNDIASVIKDKGSNEVNYYLQVAPDTVEKLEDILEQSNEYLETVVLSDNLKHVLKSALHGSYLMYSLSKRYFGKTEPNW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRL0</accession>
    <name>A0A9P6MRL0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PHD finger-like domain-containing protein 5A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">PHF5A</name>
        <name evidence="2" type="ORF">BGZ80_001383</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PHF5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001310">
        <property type="protein sequence ID" value="KAG0010562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRL0"/>
    <dbReference type="OrthoDB" id="10248186at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005345">
        <property type="entry name" value="PHF5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13120">
        <property type="entry name" value="PHD FINGER-LIKE DOMAIN-CONTAINING PROTEIN 5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03660">
        <property type="entry name" value="PHF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016468">
        <property type="entry name" value="PHF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0010562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="110" mass="12313" checksum="94986970759E3436" modified="2023-09-13" version="1">MSKHHPDLIMCRKQAGIAIGRVCEKCDGKCVICDSYVRPVTLVRICDECNYGSFQGRCVICGSPGVSDAYYCANCTRAEKDRDGCPKIVNLGSSKTDLFYERKKFGFKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRP1</accession>
    <name>A0A9P6MRP1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_001438</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001327">
        <property type="protein sequence ID" value="KAG0010495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRP1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050562">
        <property type="entry name" value="FAD_mOase_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356:SF2">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356">
        <property type="entry name" value="FAD-DEPENDENT MONOOXYGENASE ASQG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0010495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="190" mass="21025" checksum="D24CBA5F8540277B" modified="2023-09-13" version="1">MANACRGFPCPYGGTLADLIDKTPVDRISKVLLEEKFFETWYHGRTVLLGDACHKGAAQAMLDAVSLANHLYEIPSKSPQDIQATFGSYYKERVAHGKAAVQGSRQMGKLSGGHKWTEAVARSMFLNVIPNKVQQSMIDKMLSQRPQAIFLPFVEDRGEFKAKVQTQSSRMRTLSGLCLQLYGGRVAENA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSI0</accession>
    <name>A0A9P6MSI0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Negative regulator of the PHO system</fullName>
            <ecNumber evidence="2">2.7.11.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Serine/threonine-protein kinase PHO85</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="primary">PHO85</name>
        <name evidence="18" type="ORF">BGZ80_000365</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">When phosphate concentrations are high it phosphorylates the PHO4 transcription factor thus establishing repression.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="12">Interacts with a number of cyclins.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.22" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010001073">
        <property type="protein sequence ID" value="KAG0011879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSI0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000062">
        <property type="entry name" value="PHO system negative regulator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000410">
        <property type="entry name" value="Probable PHO85-cyclin-dependent protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF46">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 14 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 14 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 15" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="17">
        <location>
            <begin position="4"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="298"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="298"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00041795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00053974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00066118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00073154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAG0011879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="387" mass="44807" checksum="A61583A4501DC106" modified="2023-09-13" version="1">MERYQALEKIGEGTYATVYKGKNRSNGDAVALKEIRLDSEEGAPSTAIREISLMKELRHPNIVRLHDVIHTENKLTLVFEYMDQDLKKYMDQHGNRGALGHIVIKAFMYQLLKGVAFCHENRVLHRDLKPQNLLINRKGELKLGDFGLARAFGIPVNTFSNEVVTLWYRAPDVLLGSKTYSTSIDIWSAGCIMAEMYLGRPLFAGSNNQDELMKIFKVMGTPTEETWPGVSKLSEYRKDFPYYPPKPLSSVVPMIDTFGMDLLMQMLIYQPQRRITAKDALNHVYFNDIRGYANIQQQQQQQQQQQQQQAQMNGQMMPQQQQPPISTNSQQHVYQQQPQIPQQPPLPYQAVQMQQQQLLQQQQQQQQMQQQQAYSQQQQMHTMPQHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSK8</accession>
    <name>A0A9P6MSK8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001014</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001224">
        <property type="protein sequence ID" value="KAG0011019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSK8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="92"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0011019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="538" mass="62010" checksum="765B7AF589D4D4A4" modified="2023-09-13" version="1" fragment="single">MFDIPELDEIVCVQLCRHSLAKCAQVNKKWHRIVIPYIWHDISDLRSIPQKMVFYKMVLMDYVEELHHRYQQQQSPKEDHDLEQQHLQEKQSSSSSSSSSPPLSLLTKYEKGTMDFHTKAGFAICSNTALLLNLVIRNGPVEFWRLKYLLNRCSNKLEELTLNTIVEGKEDGKVEEEHKEEEVLNTGAQPKCLRLNLYGDVLEPKAFWLWLWRHCIYVIRLQVQYVGDFAQRLAEGMLTHIFNLDRIELGSETFSYKDENGYYVSDEKLRDDQVAILLSSCRKEWKAVQVRSSASFGESSSASLANHFSTLEELVILGGVSLGRDDLRRVLASYPNLRALVTIDNGTYYNIDIMCVELYAKSFVDLDHETGALNTWACEKSLKVLKVLITHVCDFSDPYSASQSQVYKRLARFINLETLWLGHDPRIETELHPDYSVERQDDCLQMSLESGLDTLQGLTALQELNVSNMDTLIGIKELQWMTQRWPQLRIIIMGMRRIVIRQLRSGCMTTIQRLNCRWRCGVTIEIKTGVTSSPATNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MT21</accession>
    <name>A0A9P6MT21_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_000415</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001085">
        <property type="protein sequence ID" value="KAG0011799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MT21"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055496">
        <property type="entry name" value="DUF7068"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46312">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46312:SF2">
        <property type="entry name" value="NUCLEOTIDE-BINDING OLIGOMERIZATION DOMAIN-CONTAINING PROTEIN 2-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23238">
        <property type="entry name" value="DUF7068"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13646">
        <property type="entry name" value="HEAT_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05729">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50837">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NACHT" evidence="1">
        <location>
            <begin position="198"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="990"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0011799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="990" mass="111122" checksum="82D43C640F7F9E03" modified="2023-09-13" version="1" fragment="single">MEASIHQEQVIGFHLTNTQEQPNEPSLSVTSLKFKALAGWETLVKSAKHIFGMPTSPSQETTSAGPLIPKLIPDNQTTSNVEVAIYHGKTPITSGSSPARLCFNRYQVALQNYYEPYLNIQRISGDTLSLDSCYINLAIVEAPDQRQKDKENLKTQAAIFYRMRSYEEVARTNMEAPIPLKKLFDRRKLRDGREDVPKMILVQGRAGIGKTTLCKMLIHAYQQGFWNDRFDAVLWLPLRQLAKLSARNLEDILRQKYFAHHPELEREELVAALSARRDRVLFVLDGLDEIISNAKRDIGAPLESFLRHLLRQQHVVITSRPYGVDMSILPKLDLELETIGFSTRNIKDYLVNVLDPVAARAVEKFIQQTPLIQDLANIPIQLDIICYCWDSLPPDLSNITMTELYQLMVTRLWRKDGVRLQKWEELGIGQINRLRPYQLDRVMAIEREYLGYLAFKGIQSHQIEFEESVLMDVMEELDQLRQRTNQDDLPLQLIDGLKQTSFFHTVDSDLDAVKDKSQCSWHFLHLAFQEYFAATWLARHLQNSPKAMMTVEETKAFIREHKYNPHYQIVWWMVAGLLQGEALITFFEVLQAAPVDLIGAYHHHLLAACLKEGRGQLGQLDIVIMASLEIQLEKWLEFEMSIYGNRNGRSILGSMSYFPQELLIRNIGQSGASRDYFIRTLGKHASLTQPAMEVLFNILQDEDSRVRETVVAALGNQLILSEPSFQALNGALQNKDVNVRRSAAIALGKQSTLHESAVLALIGALNDGNVNVRRLAVTVLGKQSTLPESALVALIDALHDGNVNFRCSAACTLAIQSTLPKSTLQALDDASKDNDKDVRFIAAGALGIQSILPEPTPLALICGLQDEDGDVRMSAAAELRTQSTLSELPLLALIGALQDENVHIRIQAAMALKKQPTLPELTLQALSNALQDEDDYVRLSVASALKKQLALPESTLLALGRALQDKNVNVRRSVADALGKQSTLPESTLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MT65</accession>
    <name>A0A9P6MT65_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Elongation of fatty acids protein</fullName>
            <ecNumber evidence="10">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_000212</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>an acyl-CoA + malonyl-CoA + H(+) = a 3-oxoacyl-CoA + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:50252"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:50253"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the ELO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="10"/>
    <dbReference type="EMBL" id="JAAAID010001037">
        <property type="protein sequence ID" value="KAG0012090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MT65"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009922">
        <property type="term" value="F:fatty acid elongase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034625">
        <property type="term" value="P:fatty acid elongation, monounsaturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034626">
        <property type="term" value="P:fatty acid elongation, polyunsaturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019367">
        <property type="term" value="P:fatty acid elongation, saturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030148">
        <property type="term" value="P:sphingolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042761">
        <property type="term" value="P:very long-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002076">
        <property type="entry name" value="ELO_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157:SF169">
        <property type="entry name" value="ELONGATION OF FATTY ACIDS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157">
        <property type="entry name" value="FATTY ACID ACYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01151">
        <property type="entry name" value="ELO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5 10" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7 10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="26"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="65"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="121"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="172"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0012090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="191" mass="21829" checksum="D7E9B6177A4E36BE" modified="2023-09-13" version="1" fragment="single">MGSGPMPAGIPFPEYYDFFMDWKTPLAIGATYVVAVNLFNPKVGKVSRVVAKSTNAKSAEKTESGAAMTAFVFVHNLLLSIYSGVTFYHTFPALIESYRTHNLYDAFCDIDKSFWNNALGYWGYIFYLSKFYEVIDTIIIILKGRRSSLLQTYHHAGAMITMWSGIKYQASPIWIFVIFNSFIHTIMYCYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MT80</accession>
    <name>A0A9P6MT80_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Eukaryotic translation initiation factor 3 subunit C</fullName>
            <shortName evidence="4">eIF3c</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Eukaryotic translation initiation factor 3 93 kDa subunit homolog</fullName>
            <shortName evidence="4">eIF3 p93</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Translation initiation factor eIF3, p93 subunit homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">NIP1_1</name>
        <name evidence="4" type="synonym">NIP1</name>
        <name evidence="8" type="ORF">BGZ80_000450</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the eIF-3 subunit C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001095">
        <property type="protein sequence ID" value="KAG0011739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MT80"/>
    <dbReference type="OrthoDB" id="29647at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005852">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031369">
        <property type="term" value="F:translation initiation factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000300">
        <property type="entry name" value="Eukaryotic translation initiation factor 3 subunit C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03002">
        <property type="entry name" value="eIF3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027516">
        <property type="entry name" value="EIF3C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008905">
        <property type="entry name" value="EIF3C_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058999">
        <property type="entry name" value="EIF3CL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13937">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITATION FACTOR 3, SUBUNIT 8 EIF3S8 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13937:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05470">
        <property type="entry name" value="eIF-3c_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26569">
        <property type="entry name" value="EIF3CL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4 8" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="7">
        <location>
            <begin position="586"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="207"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="785"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="158"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="10"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="30"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="213"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="803"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="825"/>
            <end position="835"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0011739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="842" mass="94651" checksum="12F469032525884C" modified="2023-09-13" version="1">MSRFFRTGESDSDETESDYSDELTASESEDHSDSDDDSSSEDDQPGKKPQGRLFVAGSDDSDSEDDTVRVVRSAKDKRFEEIDLAVTAMANGQKINDWVSVQNEFDRANKALQKAAGIIAQSGVPKFYIKAIAELEKAIQSGLDKEKTASKKMNASNAKALNSMKQKVKKNNRLYEKEIQEYEKDPEHYDVQEEEVVVASKTKAKKPKKVLSESEEEESGEEEEEADDGFTPVGAGGKTVEFTQENLFKKLKEVIDARGKKNTNREEQVRILERLLVIANTPYQKILVLLNLISAQFDFAIGLSGYMSISLWKNAEKYLNNLLTILESNSGYIVKEDIPEEDDIEKDRVPEDGKTVFIQGSIIAFIDRLDDEFTKSLQNIDPHTTDYVDRLKDEVGLYAVIVRSNAYFRGLEQTDAICRTTMRRLEHLYFKPDVVIIAVENATAALLPQKIANPAKESAALIHDLCVYLYKNANSLQRTRAMLCHIYHHALHNRFFVARDMLLMSHLQETIHQADVTTQILHNRAMVQLGLCAFREGMIRESQTCLQDISGTGRVKELLAQGLQAQRYGAVSPEQEKLERQRQLPFHMHINLELLECVYLTCSMLLEIPAMAASGANPENRKKVISKPFRRMLDYNSRQVFSGPPENTRDHIMGAAKALASGEWQKSIELINAIKIWDLMPSTDKIKEMLGHKIQEEGLRTYLFSNASYYSSVGLDQLAKMFDLPLATVVSIVSKLIWNEELSASIDQVTNVVVLHHVEATKLQSLALAFAEKAAGFVEGNEKLLESKTPQQGERPKKGPNANKDQTTGKQQQQRTMGPRGNRGGRNQFNNGLGNSVRGGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTL0</accession>
    <name>A0A9P6MTL0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_000196</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001033">
        <property type="protein sequence ID" value="KAG0012118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTL0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0012118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="271" mass="31003" checksum="91F15A2D952F6273" modified="2023-09-13" version="1">MSLCPELKSIFWHGGMPISAIHRFTIGIVDRGEFKKLDSLDLTGLFIRDDDLRKVIKHMKQPIKRLVLVQTGFGPSSLTALELHFHVIQELNLVDCLEISSKNIARLLRSCPLLVSFKAGELSSLDVKEDESWPCSDRLLTLLVNIQLAEDDVQEASRRVFACLSKLTSLRLLNIAKYTSVMGSSQKSGRPLQLRLDCGLSLLSTLRYLELLIFDRSRQSMTMEEGIWIKTNWKRLVAIGGKFNDNNEQDIQIRNLFQDLNSRYDRRRLKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUL4</accession>
    <name>A0A9P6MUL4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha</fullName>
            <ecNumber evidence="4">2.5.1.58</ecNumber>
            <ecNumber evidence="3">2.5.1.59</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">CAAX farnesyltransferase subunit alpha</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">FTase-alpha</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Ras proteins prenyltransferase subunit alpha</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Type I protein geranyl-geranyltransferase subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">RAM2</name>
        <name evidence="14" type="ORF">BGZ80_010578</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein prenyltransferase subunit alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.58" evidence="4"/>
    <dbReference type="EC" id="2.5.1.59" evidence="3"/>
    <dbReference type="EMBL" id="JAAAID010000750">
        <property type="protein sequence ID" value="KAG0014225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUL4"/>
    <dbReference type="OrthoDB" id="10255768at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005953">
        <property type="term" value="C:CAAX-protein geranylgeranyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005965">
        <property type="term" value="C:protein farnesyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004662">
        <property type="term" value="F:CAAX-protein geranylgeranyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004660">
        <property type="term" value="F:protein farnesyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.120">
        <property type="entry name" value="Protein prenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002088">
        <property type="entry name" value="Prenyl_trans_a"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11129">
        <property type="entry name" value="PROTEIN FARNESYLTRANSFERASE ALPHA SUBUNIT/RAB GERANYLGERANYL TRANSFERASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11129:SF1">
        <property type="entry name" value="PROTEIN FARNESYLTRANSFERASE_GERANYLGERANYLTRANSFERASE TYPE-1 SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01239">
        <property type="entry name" value="PPTA"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48439">
        <property type="entry name" value="Protein prenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51147">
        <property type="entry name" value="PFTA"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0637">Prenyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00040965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00041392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00042436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00043086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00043219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0014225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="330" mass="38415" checksum="458E1523E325E0C6" modified="2023-09-13" version="1">MDEVPFYEKPEWADVVPIPQDDGPNPLVPIAYTKDYSTTMDYFRAICRSEEQSERALELTKIVIEMCPSHYTVWHCRQRLLKALNKDLTDELEWIKWMSSENPKSYQIWHHRQVLVDHISSVLLPASSATSETASSLITAPTIPYHELPESQQKAARDMVKVELDFIATALEEDSKNYHAWSYRQWVLTHFGQGPWWEEELSYIDGLLELDVRNNSAWNQRFYIVSTGPQGFTEEIVRREIEILHRAKHPLSEVKEFCEGLVSRTQANFSPFLHSTLLDIYEQEAKEQKKAESLSKAKSEAALLAEKIDPIRKKYWNWKKTQLNSITVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUY7</accession>
    <name>A0A9P6MUY7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Alpha/beta hydrolase fold-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_010921</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000815">
        <property type="protein sequence ID" value="KAG0013676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUY7"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF31">
        <property type="entry name" value="STERYL ACETYL HYDROLASE MUG81-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="2">
        <location>
            <begin position="141"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0013676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="382" mass="43043" checksum="CADC984557543B32" modified="2023-09-13" version="1">MYLLGKTPPIPFSFGCTIAFASRASNQLSVNQKRRVFACGLGRAQEKLGLGTPEQRAQWATLVYGKPTSQHQSRVLFDDDPKLRRIADPRGPQGHTWKGYWIPFQEQVHVINGGNRQEIFSRKTEQDINQIKVGESCDLVVLNIHGGGFVDGFPLQTLGLLLKVMKQAHEKHNIKIGYLSVDYSLSPETPYPGALNECIEAYRSLVKEYKVDARRIVLGGESAGGNLALAMLLKLNAELKDELGTPAGVFTICPYFLDPEPMKHSIYDCLVPTSCQEFVNLYSQNRPEVLSSPYYSMLNQSDFSCTPPILVIFGGAEILRPSIERFVTNFKNGGGDVEVHLKEHHPHTWFLIDQFSTERDREEGRDILVQYLARIYEKRNVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVF6</accession>
    <name>A0A9P6MVF6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Protein M3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ECM3</name>
        <name evidence="7" type="ORF">BGZ80_010744</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000782">
        <property type="protein sequence ID" value="KAG0013968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVF6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040254">
        <property type="entry name" value="Ecm3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004776">
        <property type="entry name" value="Mem_transp_PIN-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31274:SF1">
        <property type="entry name" value="AGL149CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31274">
        <property type="entry name" value="PROTEIN ECM3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03547">
        <property type="entry name" value="Mem_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="77"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="119"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="460"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="500"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="546"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="578"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="614"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="179"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="331"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="182"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="204"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="230"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="253"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="280"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="374"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0013968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="640" mass="69985" checksum="1DC93D13E978CE1F" modified="2023-09-13" version="1">MAKHGLLSPAGAKVVAGLILNYTLPALLFAKMITCVDRSNVGELGFIALVAVFYITLGAFMGLIIQRTKLVPKRLYWGIVAATMFTNFGDLPISIILAVSDHPPFLVGDGPRGTTYSSVFIAVFYLFLFPLGGYRLIRYDHVKETERLQNLIREHNNHEQSNSNDCALSENAVTLSPDSIEQQQLQQQLRQSQHLSSPGHHYQPQRQGQGMPSSFSATSTMISMDCPPEDNAKELRYRPNDQEEYGSPRDMESPSQGRFDSSSMESSSLPRATNPFIHVPTQNDDNSSSDSGRSSPTPSSQHQHLYPLQNLRSDGWRYSIDSMVSSGTGATRFSAGHDDDHNLIQPMSKAGGPMRKKSLRSPVFNGYQPPPLHPHSNSGSSSTSPLRLTPPVRIGVESCAVENANGAPDNMATVSLGPTDAEISMEPLPKVPPALQNAYNSTHSGQVHWFWRIFHSTREYLTPPTIGLLIGLSVALTPLRDLFITTPDPLSTSTPDDLPILGFILDVTLLLGGCCVPLGLTVLGASLSRLKPGRMRPLIPTMAMITIAKLVISPCIGIMLVQFVFVQHFGWVPAQNHMLRFTLMLTSGSPTSITCFVLAQVWDRRTKNAGSEMAAIIAVQYAVSVVSLTIGSACMMYYLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVQ7</accession>
    <name>A0A9P6MVQ7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">GDT1 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_009869</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the GDT1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000630">
        <property type="protein sequence ID" value="KAG0015423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVQ7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015085">
        <property type="term" value="F:calcium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005384">
        <property type="term" value="F:manganese ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032468">
        <property type="term" value="P:Golgi calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032472">
        <property type="term" value="P:Golgi calcium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001727">
        <property type="entry name" value="GDT1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049555">
        <property type="entry name" value="GDT1-like_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12608:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 165"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12608">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN HTP-1 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01169">
        <property type="entry name" value="GDT1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01214">
        <property type="entry name" value="UPF0016"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040545001" description="GDT1 family protein" evidence="6">
        <location>
            <begin position="33"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="101"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="131"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="163"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="252"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="295"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="327"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="221"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="181"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0015423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="351" mass="37912" checksum="24FF99D6580B47BE" modified="2023-09-13" version="1">MSTGMQRFKLRHVLVIALVLACLILSFDNTSANAIDVPINDDDLDLSLVNTGGDSEGALGLHRSVAKNVDEFSNYDDSDQDTSSSDQLGGIDLSAEETQSFFLSLAMIMVSEIGDKTFLIAAIMAMKHPRFLVFSAAISALAVMSILSAAFGHAVPNLIPRTYTNYLAAILFFCFGIRMFYDGYNMTEEDAKHELEEVTQELQDKEDLELLQRAEAGSATAANMDEGGEDSSNIVGSVPPLKSTSKKSQSSGLVNLFQLLFSPVFVQTFAMTFLAEWGDRSQISTIALAAAHNMIWVSVGAVFGHSICTGVAVIGGRMLASRISVRTVTLAGAVVFEIFAIVSFYEAMYDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVY2</accession>
    <name>A0A9P6MVY2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_009703</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000604">
        <property type="protein sequence ID" value="KAG0015696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVY2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0015696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="281" mass="30295" checksum="9398011F5840D254" modified="2023-09-13" version="1">MTGCSGVAPVKLRYGDPKNLDTSKTPACEPTNLEAGSCTFIPTQAGPAYSFSATDVSGEETYSGPFKVEDSPSASPMVAAKKLAAPALKAENSTPAPEIKSAPEAKKSAPEVKKSAPEVKKSEAKPVATMNKPKVAMHKNAKEMRKRMLYDMVGLMMKKEEKLHSMLRSIVVLITLAVVAASFIQASPASLLLPDATITVSEWTILTPQWPLLERRAYEVHIKGCKGRCNVQLRYGSASNLMTDQVPACRNVDFSTERCIFIPPRPGAGFAFSTVDTTNDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MW54</accession>
    <name>A0A9P6MW54_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Prefoldin subunit 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_009532</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the prefoldin subunit beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000580">
        <property type="protein sequence ID" value="KAG0015948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MW54"/>
    <dbReference type="OrthoDB" id="248120at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016272">
        <property type="term" value="C:prefoldin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051131">
        <property type="term" value="P:chaperone-mediated protein complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23161">
        <property type="entry name" value="Prefoldin_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.370:FF:000003">
        <property type="entry name" value="Prefoldin subunit 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002777">
        <property type="entry name" value="PFD_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009053">
        <property type="entry name" value="Prefoldin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21431">
        <property type="entry name" value="PREFOLDIN SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21431:SF0">
        <property type="entry name" value="PREFOLDIN SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01920">
        <property type="entry name" value="Prefoldin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46579">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="75"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0015948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="127" mass="14628" checksum="AD93ACD235E52A2D" modified="2023-09-13" version="1">MSSAAALQKKLEADSNAYQALQKDYTKAVESRQRLDSQLQENKLVQDEFKLLKDDANIYKLIGPVLTKQDKAEAVTNVDKRIDFINAEIERVEKQLKDLQEKTEKKRIELVETQTALQQHAAQQQKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MW95</accession>
    <name>A0A9P6MW95_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein yippee-like</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_010324</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the yippee family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000705">
        <property type="protein sequence ID" value="KAG0014650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MW95"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034751">
        <property type="entry name" value="Yippee"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004910">
        <property type="entry name" value="Yippee/Mis18/Cereblon"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039058">
        <property type="entry name" value="Yippee_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13848">
        <property type="entry name" value="PROTEIN YIPPEE-LIKE CG15309-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03226">
        <property type="entry name" value="Yippee-Mis18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51792">
        <property type="entry name" value="YIPPEE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Yippee" evidence="5">
        <location>
            <begin position="51"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU110713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0014650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="156" mass="18119" checksum="4BF80099AEA8A870" modified="2023-09-13" version="1">MDASLPHQVYLKGDQIYTCNSCHAHLARNEDIISKVRLTATHSRSTHARHNKIRPIIILTYSLYKLQLLLFYKGFQGRHGRAYLFKNVQNITLGPKEDRILMTGLHSVADISCTICQSVIGWIYIYAFEEAQKYKEGKYIVEKAKISKENFWIQNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXD7</accession>
    <name>A0A9P6MXD7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Vacuolar membrane pq loop repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_008595</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000470">
        <property type="protein sequence ID" value="KAG0017137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXD7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1280.290:FF:000012">
        <property type="entry name" value="Vacuolar membrane PQ loop repeat protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051415">
        <property type="entry name" value="LAAT-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006603">
        <property type="entry name" value="PQ-loop_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16201:SF44">
        <property type="entry name" value="SEVEN TRANSMEMBRANE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16201">
        <property type="entry name" value="SEVEN TRANSMEMBRANE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04193">
        <property type="entry name" value="PQ-loop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00679">
        <property type="entry name" value="CTNS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="173"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="254"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="290"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="321"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="139"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="205"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="370"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="372"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="390"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0017137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="418" mass="46182" checksum="B3F5C316054FE3A8" modified="2023-09-13" version="1">MGAHTVLYWLASQGAQTATSIDTEDNAPTRRYLSNVAGSLSILCWFIVFTPTSVKASFESVITHANPEVLTTIHEHHGELAPLVAGSSLVNYSSISPSEHVHENDHDRVIHEAAKVANATASHYAEDHLHPDHAYPREYAHRHRRPSTHSAMTTHSGRYRSKMAKRRKMVRRALMILSPLVLVTIFAWAYYDWYQCTIGEGDSGDGSRCGRGHGGHGKLPPTPSDPSDEGNIVSMMGGKGDKNLPGDEKSTFELWLPLVLGWGSAVLYLGSRIPQIYKNWRLKSCEGLSAMMFVFSVLGNVLYVASIFLNSLEIDYLIRNMPWWLGSGGTLFFDFTIFFQFYIYRFNNPLSEALKEAAAAGELDENALMATADDESVEDDTDSDSTTETPIQNNKGKSSNTIGKNNQHHAAASNSTNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYJ9</accession>
    <name>A0A9P6MYJ9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_006871</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the acetyltransferase family. MAK3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000342">
        <property type="protein sequence ID" value="KAG0018685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYJ9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031417">
        <property type="term" value="C:NatC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004596">
        <property type="term" value="F:protein-N-terminal amino-acid acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044542">
        <property type="entry name" value="NAA30-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45896">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45896:SF1">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="5">
        <location>
            <begin position="505"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="108"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="13"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="111"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0018685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="661" mass="74501" checksum="4C6DCCE7CC2B887B" modified="2023-09-13" version="1">MTWERPSVMPIATSPSATTISRESQPAQSCPEITTAKIHMNKTSPSLPSPPLSPHSDHGARLNSLPMLPLATTPSPAPSCSTTNDDSSLISPSAETFSHHSLDSFGLLEKSNSSSSSCTSTSSLTSAETPFPVGDPSVEEIDETVPMLPSQLRRRHESMKLLAKKQQPVIFELGDERQEIRSQDQTNLIIELDSQELPDDKIETDETEVINASYHSGAMIRAKSYSMFESSNFDHTPSHPWGPSQQMEYLNGEMPTKDWVMIQSKMQALELEISHIRRTNMLLNQELDKVNAHLSRVTSNSEDDEDGQGAGWRREYEFMVQQVDWMHQQLQLAHAEKQGRSQYQAEMTRELCAEVKGLTASLRMWQSAFQEAEEKYRRKCEGERVLKQTLREREGQLSSLVEKLTGCESEFQKSLSNYEELVRLSAELELIEGSTNKSSVPKQLALNDSLTREGISDMPGTFPGQQWHCESKSEIALVPATDTTTDHNNSNSTTSSSIPEVLPPIDYVGYESERQLQDMVSLIENDLSEPYSIYTYRYFLHQWPKLSFLAMDREKDKCIGVIVCRLEPHGHTKANRGYIAMLAVSKEYRKRRIGSTLVLMAIEAMKKAGADEIVLETEYTNQSAIALYLQMGFIKDKRLKLFCKPELEDTSSYDADDRMIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYW7</accession>
    <name>A0A9P6MYW7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_008187</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000437">
        <property type="protein sequence ID" value="KAG0017533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYW7"/>
    <dbReference type="OrthoDB" id="2440768at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="298"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="377"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="202"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="266"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="386"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0017533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="444" mass="46136" checksum="A0F1A5A62CD00FBD" modified="2023-09-13" version="1">MISKQSSRCRQQQQQYSLSLRSTVLLIIFSSYWIQLASAKLSCTSPTSSGKSKIHPGTAFTLGFSGAALDTALSTITADLVCSSTGTTALSLGSGYNSSNYSPESPQVTITDSQAAEALASCPSNAFHVKYSTSSSLSQQVASCKGVLSIDDDDVVGSSMPTSLLPSLSAQPSSSETATSQSPIQTITTTAVTATATVTTSGIPVTTPVTTPEITTATTPAINATTVTTSVHTTTPPKSTTPSIVPTTAEGGSGGGGDGNNGGQATSSDSTTLPSPSGNATMPSTASEFQSTSSPPTAVVAGAGVGVVASIFVILAGLLIWRKRQQRKRDLDLFIGDSSLAAASGFSATPIYARSDPDEDRQLTRDDSVMVPVPMSENMSRSQHGSPPPLAPTQPYPAAISMGQQDMGYYNEEDVDYYQQQSSYRLPYSHPNYDYNSYGHHHGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYX2</accession>
    <name>A0A9P6MYX2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">vesicle-fusing ATPase</fullName>
            <ecNumber evidence="3">3.6.4.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">VPS4</name>
        <name evidence="16" type="ORF">BGZ80_008162</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.6"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endosome membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.6" evidence="3"/>
    <dbReference type="EMBL" id="JAAAID010000435">
        <property type="protein sequence ID" value="KAG0017560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYX2"/>
    <dbReference type="OrthoDB" id="29072at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045324">
        <property type="term" value="P:late endosome to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007033">
        <property type="term" value="P:vacuole organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02678">
        <property type="entry name" value="MIT_VPS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19521">
        <property type="entry name" value="RecA-like_VPS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.80:FF:000004">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000043">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000015">
        <property type="entry name" value="vacuolar protein sorting-associated protein 4A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.80">
        <property type="entry name" value="Phosphotransferase system, lactose/cellobiose-type IIA subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007330">
        <property type="entry name" value="MIT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036181">
        <property type="entry name" value="MIT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050304">
        <property type="entry name" value="MT-severing_AAA_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015415">
        <property type="entry name" value="Spast_Vps4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045253">
        <property type="entry name" value="VPS4_MIT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23074">
        <property type="entry name" value="AAA DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23074:SF83">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 4A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04212">
        <property type="entry name" value="MIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09336">
        <property type="entry name" value="Vps4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00745">
        <property type="entry name" value="MIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116846">
        <property type="entry name" value="MIT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0967">Endosome</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="MIT" evidence="15">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="14">
        <location>
            <begin position="161"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="72"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012674"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0017560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="437" mass="48645" checksum="736586EE1680CA7A" modified="2023-09-13" version="1">MADFLPRAVETVKRATEEDTKGHLEEALPLYQTALEYFLTALKYEKNERVRDTVRKKVVEYMARAEKIKEHLAKMEEKPKKKAMANSSNGKGSKKKDSDDDDEDDADTKKLKGALTSAILTEKPNVKWTDVAGLDVAKESLKEAVILPIKFPHLFTGNRTPWKGILLYGPPGTGKSFLAKAVATEANSTFFSVSSSDLVSKWMGESERLVKNLFQMARENKPAIIFIDEVDSLCGSRGEGDSEASRRVKTEFLVQMNGVGNDMDGVLVLGATNIPWQLDAAIRRRFEKRIYIPLPEPHARAKMFELNVGKTPCTLTAQDYQYLGQITEGYSGSDIAIAVRDALMMPIRKVQISTHFKWVDAPSRADPSRMTKHLTPCSPGDPAAIEMSWEQVEGDQLLEPSLGIQDFLKAVKTVRPTVSADDIVEHTKFTLEFGSEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZG5</accession>
    <name>A0A9P6MZG5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">6-phosphogluconate dehydrogenase family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_006535</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HIBADH-related family. NP60 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000323">
        <property type="protein sequence ID" value="KAG0018935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZG5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029154">
        <property type="entry name" value="HIBADH-like_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015815">
        <property type="entry name" value="HIBADH-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051265">
        <property type="entry name" value="HIBADH-related_NP60_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43580:SF8">
        <property type="entry name" value="6-PHOSPHOGLUCONATE DEHYDROGENASE NADP-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43580">
        <property type="entry name" value="OXIDOREDUCTASE GLYR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14833">
        <property type="entry name" value="NAD_binding_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000103">
        <property type="entry name" value="HIBADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6-phosphogluconate dehydrogenase NADP-binding" evidence="5">
        <location>
            <begin position="12"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="3-hydroxyisobutyrate dehydrogenase-like NAD-binding" evidence="6">
        <location>
            <begin position="185"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000103-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF14833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0018935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="327" mass="36210" checksum="9AF49A5DBEEF2269" modified="2023-09-13" version="1">MNNLLHLKQQDRIGWIGLGEIGYHMASNLHRYLASLHLNMTVWNRDPAKSAKMHHHGPRVAKSIEDLVAQSNIIFTSLANDAAVEEIYLQLIELASQVDHSIIFVETSTIYPALATKLSKQLSAYPQHTYLQCPVFGRPPVAKAAKLIWVTSGDEKAIKRMCLYFTTMSKSIIHLKTLDVAKACNFKLIGNFFVAGTMELLAEGLTLAEKADVDQESVLKFIETFMPGPVWLEYSRKMADGAVLDKEDGFSVDLGLKDVGHMRQLAQDTGASLPTADLVYDHLKAIQDKGLGGQDWSSLINSLRDASKLPLIVEKQSYAGEKGEKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZJ8</accession>
    <name>A0A9P6MZJ8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_007373</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000376">
        <property type="protein sequence ID" value="KAG0018274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZJ8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052394">
        <property type="entry name" value="LRR-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24114:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24114">
        <property type="entry name" value="LEUCINE RICH REPEAT FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="16"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0018274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="593" mass="61611" checksum="9179420ED1C8E888" modified="2023-09-13" version="1">MLSIYMRFVQELPTGFASKTSHPVRVIMGNSCLTSLTLTGNHIGDSGVVVLSKALKTNLTLTTLDLKANSIEEKGAVALSEALMTNSTLTTLRLSRNSIKDNGAEVLSEALKSNTSLTTLIMENNMIGTRGAQALSEALKSNSTLTILTLGSNEIGTAGAQTLSEALKANLSLTVLDLMFNKIEDNGAVALSGALKSNSTLTTLNLGANKIGINGAQALSEALKINSTLTTLYLMANSIGENGVVALSEALMINSTLTTLGLSKNPIKDDGAVALSRALKSNSTLTTLTLGDSQIGTSGAQALSEVLKVNSTLATLDLIVNSIGENGAQALSEALRINSTLTTLKLRRNSIGENGAVVISEALKSNSTLTTLILENNRIGTNGAQALSEALKINSTLSILTLRANEIGADGTQALCEALKINVTLTTLELGWNSIGDNGAAALSEILKVNSTLATLKIMRNGIGFNGAQVLSEALKTNSTLNTLSLRYNSIEDHGAQALAEALKTNSSLTALDLGCNKIGDNGAMALSGALKTNTTLTTLELDGNEIGTNGAQALLDALKTNSTLTTLELGHETMKLLPYPLCQGLGRCTTIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZL0</accession>
    <name>A0A9P6MZL0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CBS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_005279</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cysteine synthase/cystathionine beta-synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000261">
        <property type="protein sequence ID" value="KAG0019778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZL0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01561">
        <property type="entry name" value="CBS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000118">
        <property type="entry name" value="Related to CYS4-cystathionine beta-synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050214">
        <property type="entry name" value="Cys_Synth/Cystath_Beta-Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001216">
        <property type="entry name" value="P-phosphate_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10314">
        <property type="entry name" value="CYSTATHIONINE BETA-SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00901">
        <property type="entry name" value="CYS_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0129">CBS domain</keyword>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="5">
        <location>
            <begin position="352"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0019778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="487" mass="53091" checksum="6B02453C6E7C7FAA" modified="2023-09-13" version="1">MATTKLAPPAITDAIAGMSLGLLVYGFTGGQIELLAKTEFSNPSGSIKDRVAQRILSNLRAANKIKESTALIVPGSGNLAISLAALSSQHGQYKVIGLVPERTTHDRIQLLKSFDVEIVRTQVEAHAESAESQFSIAKKIATNLPEAVLVDEYSDGANVQVHSQETAEEIFIQCQGRLDVLVVGVESGGSVTGLARTLKAKIPGLKVVAVEPEHSSIQDGVTGNCAWKVEDIGGNFTPTILDKSLIDEWIQVSDRESYSTARQLIREEGVFGGPSSGSVVAAALRYAETHLKGAAQKPRILTILNDTARNYTSTLLSDDWLLEHDLMDETLAKAAAYNRHEKYRAASVEDLQLPAAVTIPPTATVGYALDLMLTRDFSQLPVLDPTNRKLIGYISLTALTSLLEQGRAHESHEVSKWMYSFVKKGKKGSRSTYETITPNTPLADLSKFFEKHSFAVVTDDDRRWCLGVATKYDLMTFLNRRQSSGRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZP1</accession>
    <name>A0A9P6MZP1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Asn/Gln amidotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_007261</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-aspartyl-tRNA(Asn) + L-glutamine + ATP + H2O = L-asparaginyl-tRNA(Asn) + L-glutamate + ADP + phosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:14513"/>
            <dbReference type="Rhea" id="RHEA-COMP:9674"/>
            <dbReference type="Rhea" id="RHEA-COMP:9677"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78515"/>
            <dbReference type="ChEBI" id="CHEBI:78516"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-glutamyl-tRNA(Gln) + L-glutamine + ATP + H2O = L-glutaminyl-tRNA(Gln) + L-glutamate + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17521"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="Rhea" id="RHEA-COMP:9684"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GatB/GatE family. GatB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000369">
        <property type="protein sequence ID" value="KAG0018358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZP1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030956">
        <property type="term" value="C:glutamyl-tRNA(Gln) amidotransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050567">
        <property type="term" value="F:glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070681">
        <property type="term" value="P:glutaminyl-tRNAGln biosynthesis via transamidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.410:FF:000001">
        <property type="entry name" value="Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017959">
        <property type="entry name" value="Asn/Gln-tRNA_amidoTrfase_suB/E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006075">
        <property type="entry name" value="Asn/Gln-tRNA_Trfase_suB/E_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018027">
        <property type="entry name" value="Asn/Gln_amidotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003789">
        <property type="entry name" value="Asn/Gln_tRNA_amidoTrase-B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004413">
        <property type="entry name" value="GatB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023168">
        <property type="entry name" value="GatB_Yqey_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017958">
        <property type="entry name" value="Gln-tRNA_amidoTrfase_suB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00133">
        <property type="entry name" value="gatB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004012">
        <property type="entry name" value="PRK05477.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11659">
        <property type="entry name" value="GLUTAMYL-TRNA GLN AMIDOTRANSFERASE SUBUNIT B MITOCHONDRIAL AND PROKARYOTIC PET112-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11659:SF0">
        <property type="entry name" value="GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT B, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02934">
        <property type="entry name" value="GatB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02637">
        <property type="entry name" value="GatB_Yqey"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00845">
        <property type="entry name" value="GatB_Yqey"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89095">
        <property type="entry name" value="GatB/YqeY motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="Glutamine synthetase/guanido kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01234">
        <property type="entry name" value="GATB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Asn/Gln amidotransferase" evidence="8">
        <location>
            <begin position="235"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0018358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="411" mass="45475" checksum="27DC2DB1CD9E4630" modified="2023-09-13" version="1">MQQPLAQDGRIEISTVDGLDYAVTVRIEQLQLEQDTGKSLHDVYPGLTLQDLNRAGTGLMEIVTKPDMRSSKEAGILVKKLQALLRAVDSSDGNMEEGSMRCDVNVSVHEPGTPYGARCELKNLNSIKSVVDAIDAEVERQISCHENNTPVIQETRGFDASTGKTFRIRSKESAPDYRYMPEPDLPRLVLSQNEIQTLKQSLPELPDAQRDRIMQSYQLGVIETRTLMGEDGMVKYFESLMSSGRQTKSVISWYVWDACIGMTIHELLGRLHARGINFSPDVVNTSQLGSLVDCVDRGLISAKVGKSVLDLMIDGDSRDANAIVEEKGWKQMDNRDELDQLCDTILEKFPEKVKVVQGGNIGVLGFFIGEIMKQSKGRANPVILNELLRAKVGLPLAPTGATGKEKGRKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZY1</accession>
    <name>A0A9P6MZY1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004838</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000242">
        <property type="protein sequence ID" value="KAG0020074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZY1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="241"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="852"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0020074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="852" mass="96323" checksum="44F706B32E9CAD1B" modified="2023-09-13" version="1" fragment="single">DNHTGRRQRDRRFVLSSAVQHTDFKIQATSTYSNAFHVLLSEFNILVLGERQSGKSTLIEAIKNYARQDILDPIIPNYTSTTDVKSTLITTSLPRFSVFKGADDQDERSQPNQLSNDDIRQYLSLVDAEYEQLKSCLHIRKDQQKLNPRNFNFRLIDTPGLNFIKDGSRSHITDGESGVFITETLPAIIKHLGSTFAVHLVLLVISDADNYDSSEAVNFYRDILPAFDFITVVAHRDIKGDEATSPASKAPRSRHKSPYGESHADQIYFAIDNIFIRDDPIRNCLARNDIRRVLELALLNEPVFVQPKKPSFIKDLDKFLEDRYSEVLKTIHDAVATTDESNPFHNILRLTKIQCDKDAHKETILSSSPLKLIFSRKFENTWDAPTSYGPIKVEMESECEIAHVDILKHNVEILKQDGGVGADQLRLAFRWTSAFHGILEIRIYVNAATTPPHSNDIQMNINVAVRNAVPNSKGASDQYKLIMEFLERYRRFHTMHRLTSANAVHPEAIQILTIRDIDQTIPIDIFQCVEKLETAYFNIADTYKSKIASQEKAPSKIIVDDGGSARSIYPAVNGFRSHLVHRRTQNPWSKIEYIGSTMPGRHGDMHPLSLLTIPIPEESDESGRGRLHGPIVETIKVTLFQEFKIRGSSKSISFPTRRNIENGYFTMWNDIELVFGKVKFVLHGSNVVPKLSDENSIILQPERIRYYPGVVLEVVKEENSSAAAETPDIPLYPWPSTSSPNFKMPLPYILQHPSDLPTDLSPIITQSLPDSVTTMGIGSQKDSAAMTFISQDSSKLNAAEKGLEMKKEFQKNFDKLRDDIEIEKLLLTMDTGGERLGKMLEKLASEDDDIGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1A4</accession>
    <name>A0A9P6N1A4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">L-threonine 3-dehydrogenase, mitochondrial</fullName>
            <ecNumber evidence="5">1.1.1.103</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_002469</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate, mediating L-threonine catabolism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>L-threonine + NAD(+) = (2S)-2-amino-3-oxobutanoate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13161"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:78948"/>
            <dbReference type="EC" id="1.1.1.103"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid degradation; L-threonine degradation via oxydo-reductase pathway; glycine from L-threonine: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the NAD(P)-dependent epimerase/dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.103" evidence="5"/>
    <dbReference type="EMBL" id="JAAAID010000161">
        <property type="protein sequence ID" value="KAG0021412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1A4"/>
    <dbReference type="OrthoDB" id="331544at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008743">
        <property type="term" value="F:L-threonine 3-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006567">
        <property type="term" value="P:L-threonine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000077">
        <property type="entry name" value="L-threonine 3-dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051225">
        <property type="entry name" value="NAD(P)_epim/dehydratase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42687">
        <property type="entry name" value="L-THREONINE 3-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42687:SF1">
        <property type="entry name" value="L-THREONINE 3-DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="7">
        <location>
            <begin position="78"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00050613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00059023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00060557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00066604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00069940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0021412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="408" mass="44900" checksum="9B0A8FA530901152" modified="2023-09-13" version="1">MYKHSTAPIMAASSILRRSVFRTALAAPSTTVRLRNIPAATRFFSNTSAFMSPSPSSASPQATIATGSLPSTIRHPRVLVTGSLGQLGSGLVKELRSMYGNENVVASDIRNAPEDFKANGPFVFADVMDYAQLEGIVVDYKIDWIVHYSALLSAVAEKNPALALSVNMTGFQNVLELAKVHGLRLYSPSTIGAFGPSTPKIDTPDVTIMRPNTIYGITKLHNELLGEYYREKYNVDFRSARYPGILSADTPPGGGTTDYAVDIFHHAVRHGHYDCFLKKDTRLPMMYLSDCIKGTVDHLVHPEMLPQAVYNIAAVSFTPEELASEIRKYLPHFTISYPDPAHPDFRQAIADSWPASLDDSMARRDFGWKEEFGMEKMVKLMLDKIQAQVDAEKRIAMTNGSTAAAMSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-06-18" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1Y4</accession>
    <name>A0A9P6N1Y4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Anaphase-promoting complex subunit 11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">DTX2</name>
        <name evidence="11" type="ORF">BGZ80_000861</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the Deltex family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000119">
        <property type="protein sequence ID" value="KAG0022171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097602">
        <property type="term" value="F:cullin family protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003950">
        <property type="term" value="F:NAD+ poly-ADP-ribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.228.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039396">
        <property type="entry name" value="Deltex_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039399">
        <property type="entry name" value="Deltex_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012317">
        <property type="entry name" value="Poly(ADP-ribose)pol_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024991">
        <property type="entry name" value="RING-H2_APC11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF51">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18102">
        <property type="entry name" value="DTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00644">
        <property type="entry name" value="PARP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12861">
        <property type="entry name" value="zf-ANAPC11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56399">
        <property type="entry name" value="ADP-ribosylation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0498">Mitosis</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="9">
        <location>
            <begin position="802"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="10">
        <location>
            <begin position="1161"/>
            <end position="1562"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="383"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0022171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1565" mass="175860" checksum="981B08E8DC5213F0" modified="2023-09-13" version="1">MPLVQSCSAEFTDLFQRFFENPPPDLEKKTLPIIRPFGSNLPDQPGAGSSLQLDISPNDDKELFNLIAGDFLGHTRDMSDYSIQSIRLLRNPVVWKRYQAEKQLRRQLAQQEREMRQQTRATAHAPQNTATWASSGTCPFDEDDPNELFRDEILYHGTFKDRITSILLNGLDPKMTVRANYGRGVYFSDSIEKCMQYVDKQTSLNQEYSIVLCCVLLGRVLVESYEKSKRKLGQHTMFLPEGYDSAVAHDVFKEWIVFEKSQILPLCVINFTASNEPESFFRLSTHQVLFRGLNTYPSSISDIPKVYTVPTPVDYSNPKESLKAQEWRDPEDETNRMLSNAFNIPANTTKICNILNSANKSWVVLSATSGHMCHISDQSMTMLLQQSKNIETLKDRMNTQKRDILKIRTQQRVYINSQIQNIRNSAKLMELLVTREPELIRIENEGRRIVGIIEQTKKELIQSGREHLIHSHEFQLSIHPYRQQLEQLKVQYDAVFEPLAEWNKEELALGERVIKQQQELQKQIESDKDSEMRQLDAIRTETERIKREAQVATRLIDQMELNKLLAAAKASRESLASGARSGDFQMKGVDVHVCNTRAWPQIVSEMLMPVMMISQLKYNVDLLNDNNPQRRAPHVRDAGVHDVSEWWHAAPMGVFQAPAATSLFWPIDPRRRLPNRRLFSFRDYLEWIFMEKENRIRKRQLRLDQLSSQSTPSALPSDLLDSADVKQLLQDQWDRLDPTITQSIRGLSSRFGTVVFNREERQKELDQMGADLLNELFEEAKPHMLIRDETKSGASGPALAECPICQEDLVLPEANGATTTTTSAPEKVVKLKSCRHCFHELCINEWFKSKDAQLKCPMCNTMCTTNAKSGAAKEAMRGQIPQKLGPMPDGVMGYSFDVRLACYFIYIIIPSHKIPNPNPGASLSDTITVNTDIRYAIVPFSARLGPLLMIRLICLFYYGHMFRIGQSLTRGSDNVVIWNGVHLRTSMTGGYGFPAPNFESNCWQEINQKGIAMGLEEHIVNMPRPDGSTPTSPTHDPHRIGGVVLPPELLEEVAAQEMVTRMFHRDQPCLFASALLPDISDSNLKNVVLFKLSHTEHSPMYLTRRARQKPYLLAEPQQQQQEEQGGQASYAYDEYPIPDVVSSDESAVQVSLSSIPKDFGYTASFSIGTYSSNDGSCELFNLLVDTGSDMVVVTSATSTDPECVLVPHRYNASASLTCEPTQNKLTDNPRWAQRYGDGTIANGTLVQDTLRFISHVDNSDSGSDPGSFTSDVASSTSLKVENQPILVVDQPGLHLFKSYGPTVDGIIGMNLRSPVISSTVIESLQKTETMNTAISKDLFLSSSISPLDPADDGSGGMGLMSLWLTKSQESGHGGELLLNAVDKSRFQGPIRWSNRGPSPFDWSVPLDRGLLLYNPQTDIYIPVPETDHTFAVLDSGSDGIYLEKAIYDALFRQVPGSKQLSNGYWRVPCEGTMELVIGIEGKLYRIPYEDWVKKPDKATTTTTTTVNSNAASSLGAGTEPGMCQARVFGSSPGPTLLGTTFLRSVYTVFDFSRPGNERMGFADLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N222</accession>
    <name>A0A9P6N222_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Mitochondrial carrier</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BGZ80_000574</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000112">
        <property type="protein sequence ID" value="KAG0022304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N222"/>
    <dbReference type="OrthoDB" id="18574at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015217">
        <property type="term" value="F:ADP transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052217">
        <property type="entry name" value="Mito/Peroxisomal_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45939:SF2">
        <property type="entry name" value="CARRIER PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G13870)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45939">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PMP34-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="257"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="97"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="185"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="312"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="36"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="215"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="346"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="57"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="72"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="215"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="353"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0022304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="447" mass="48366" checksum="E8AECB9623AE246C" modified="2023-09-13" version="1">MTYELPPIGHALSGGVAAALANVIIYPLDMATTRVQSQSTKDSDNVVARGGGGAGQRETEVLPIEFKRPEPVSSTSSSSSKSDVSVSEDGHKKITKTTIITTTTTTTRSLSSDSGLSAPTPSKKKVRYTSVADAIRKTYASEGFLALYSGLGSDTIATLTSNFVYFYIYMALRQYKEHRRKSGQLSTFQELFLGAEAGVISRLFTNPIHVVTTRQQVMGKQQQQHQQQQNGGKPAATESKVSASSIIREIYAQDGILGFWAGYAPTVILSINPSITYFLFETFKKIIIDRQMAAANSSGSASKSILAAAASLTSLQIFFISAFSKATASFLTYPLILTKTKLQTRSEEEEDSATTAAETTTTAEEGSAKEGSNSAEKKTKKFNGISDVFKTVIKDKGIAGLYTGCQGQVIKGFFSFGLMYMIKDRVVAWMLTLFLAIHNMRNRVTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2K6</accession>
    <name>A0A9P6N2K6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Tripartite DNA replication factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">DNA2_2</name>
        <name evidence="4" type="ORF">BGZ80_010904</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000081">
        <property type="protein sequence ID" value="KAG0022908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016604">
        <property type="term" value="C:nuclear body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001147">
        <property type="term" value="F:transcription termination site sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006369">
        <property type="term" value="P:termination of RNA polymerase II transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF495">
        <property type="entry name" value="HELICASE SENATAXIN ISOFORM X1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="2">
        <location>
            <begin position="905"/>
            <end position="981"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase-like C-terminal" evidence="3">
        <location>
            <begin position="1152"/>
            <end position="1350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0022908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1411" mass="158739" checksum="22896D28422C721A" modified="2023-09-13" version="1">MSGSDNNDKFRQGLGTSNSLQNLLQSLSLTDDSSAKDCESNEIIDEESHYSSTRSSLDFSFSSLHISAEDWESIDEETRNITCTVQPSQTIEVASSFKNVTKSSPATVQPRTTAQPTSENSSEPVPDSLADNNTINILGSDSEHSQLHEGYRFSPSVLAHHANTLCEKMLHLKGRQLWQQSLKRQAETSINESDRGVTSLAEATMQRGINYESRLQSAIQDKIDCEAEHDKDSFFRLAASPEGTTLCQPVFSLDEGFYTPNMKKAGIVFGRFIPDFIRILPGMLGQDGKRKKRLFIIDAKSSSHVKTSHQIQVTLYAIFLSHLIKVNKQEHLVEIDPRGGVWIPQHKEPQTFSLVFMRPIVENFIFEELPSILMKPLRSAVLDVRTTELPRLHQDRLLINILIDPLTTLPFAYSLNMFKEQSLHPTRSIANSVVHLPDETDAFTSNLIGLTVELIDNLYEWLHQISQIRPKAPILSMFIYNQSMQDSLCNLLLKVISEKSEESSTWPTATKERAMDLLVNMYEDPSFLALSELAEFNVRLPDILQLTQGFKNNNPCHDKRVFAIETALQKLLVLPVVGSYSFKHIMKYLVDVEAPSIFDESERDDDGYNLESIYHKWSNGASCDEIQSTIQRWVEQQNVILISLYKLIRHKHSNLSAILVAPQAPFKIRSRLEFRHNILAQIAFFKQWEAITAAESRRKNRITLTKDEAIQRQEIFQCRFLGRHVGPLPGEEPGVRSPRAPSNKPSSEYIAMFEISNHLNTGSITCSTFKQWILSADNPTGMSDRIRFDDINALLRAYGHGTPVIVCVPYYDPETNIVYVSGGYSNMLDNLGLTEGENYILERREYDPTLSTSMAKLVEMDKSCRLFLDLMKDPNKWGQQRPEKSADVFLESITNSIRQYDMTLSQEQAFSKVINNRLQVIWGPPGSGKTHFLALTILRFTDVLRSLSDKGRGQGSHTIVVTAFTHTAINNLVARIAKLHEAVAPHVGSEHLVRPLVMYRLKDPSSTQLNGTLIVEPADLAKLQRRTEETGNEDIVRIVCGTVWQIRRAAHPESGVDYMRNVQMLMIDEGSQLLAGDAIHAIECLDPQHGRLIVAGDHLQLGPVISGEYPSTETAFDPTGSIMKNLMRRCDNSPVQLQWVEGGADMEIGPCTSQLQDNFRMNDQLGLFMKTIYGANYQVQTPNRTLPYSGGYAGSSIPMQFRRILDPSISAVCIELQLAGDIKCPEAVRVKSDNRVAAYLEATFVAGILDYYLEMVGKDTVTSLFVAVPHHVQRLAIIDKLRLPELEQKYPMAQIKVDTIEKMQGQEADMMIVCFALFDDTTLVNELTHLYSIHRWIVALSRARCKTVLLMTPELKSPRIISGTGKASPSELERLDGWGLLQAFEKYAAQLGGKAEWPITQNFLRGIGIGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2W2</accession>
    <name>A0A9P6N2W2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Peptidase M14 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BGZ80_001734</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the peptidase M14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000140">
        <property type="protein sequence ID" value="KAG0021775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N2W2"/>
    <dbReference type="OrthoDB" id="3626597at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03860">
        <property type="entry name" value="M14_CP_A-B_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.10:FF:000084">
        <property type="entry name" value="Carboxypeptidase B2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000834">
        <property type="entry name" value="Peptidase_M14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11705">
        <property type="entry name" value="PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11705:SF143">
        <property type="entry name" value="SLL0236 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00246">
        <property type="entry name" value="Peptidase_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00765">
        <property type="entry name" value="CRBOXYPTASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00631">
        <property type="entry name" value="Zn_pept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52035">
        <property type="entry name" value="PEPTIDASE_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040323081" description="Peptidase M14 domain-containing protein" evidence="11">
        <location>
            <begin position="23"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M14" evidence="12">
        <location>
            <begin position="214"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="10">
        <location>
            <position position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS52035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0021775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="530" mass="60662" checksum="E2CA54F81F0D4B8C" modified="2023-09-13" version="1">MKNILSISVVLSFALLASQSSAQRCHMDYNDQISVIEDVNADIDFSNNGAQVIFGGRRGPHRIEHYEEPFNVKKVTYPRELENHALVRFNVRKHHIEFPIPAQFASLTASQDPVETMLENLDVWSRSRDSDFVLAHFTDLQFKLFERTMRLKGIPESEDDWKVVERDLQRVADEDAQNIYLAALDVQLANLGKKKKKGGKKPERRVDFDTWFSNYHTHTEIKDFYLQIADDYPELITFIPSIGKTVEGRDIFAIKLTAKEKDGSVREKPQIWWQGLQHAREWAGGSTVQYLTHHFATNYGKNTQITSILDDTEFIIVPIMNIDGYDYTWTRNRLWRKNRRNNGLGAWGVDLNRNWDDHFAEGGSSGFPWSETYHGPFAASEPEVQAMQDFFGAQKRIVGAIDFHCYSQLVLRPEGWTTTPSPHEKEHKFVGDKIVSLIKSVHGKKYISEPSVALYKTTGAGSDWFYGEKATEANNGQRVYSYTIELRPSDTNPGGRSGFILPPEEIIPLGEEIANAMEFFVDYVVKNPLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N374</accession>
    <name>A0A9P6N374_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">histone acetyltransferase</fullName>
            <ecNumber evidence="2">2.3.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_009206</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-lysyl-[histone] + acetyl-CoA = N(6)-acetyl-L-lysyl-[histone] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21992"/>
            <dbReference type="Rhea" id="RHEA-COMP:9845"/>
            <dbReference type="Rhea" id="RHEA-COMP:11338"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
            <dbReference type="EC" id="2.3.1.48"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:21993"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.48" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010000053">
        <property type="protein sequence ID" value="KAG0023524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N374"/>
    <dbReference type="OrthoDB" id="3361892at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032931">
        <property type="term" value="F:histone H3K56 acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051236">
        <property type="entry name" value="HAT_RTT109-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013178">
        <property type="entry name" value="Histone_AcTrfase_Rtt109/CBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016849">
        <property type="entry name" value="Rtt109"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31571">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31571:SF2">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE RTT109"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08214">
        <property type="entry name" value="HAT_KAT11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01250">
        <property type="entry name" value="KAT11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51728">
        <property type="entry name" value="RTT109_HAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0007">Acetylation</keyword>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="27"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="445"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="670"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="27"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="53"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="445"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="472"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="677"/>
            <end position="696"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0023524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="714" mass="78367" checksum="DF7E03C264E8D9A9" modified="2023-09-13" version="1">MSRPQFGVRYDSADPILRSIASELDSIYSNRDGPQTGNHVPSTADDNLPATPQQQQQQQEQESRQQTVSSFDFQLESFHTRPKACTDLFPPHVQKQRYQIITVQERLILVSIGPAAADKDTSEEKEGSQKNDKESKDGDVCAVLVAGLEVLEYHLVPINNSPSTGDNSRKPIERIIYIAKVDTSGSWPLPGINSRGLKSPTHALVKGYLNGMKSVDFTESSLYQNMLGTTADRLSSLTISSSKNVDADDNVDTVEGKDSPKDIKLTSRRAKKTSLYIFARAQPQYLFARSAKNSGKHVLDDRGLVRWWKNMVSSVYSTSASPESSSDQGGQRVHNKSKLHGWWHIPGIETERGALRIIQSPHASSTISSPESVFNWTYGYPDKGSKEMANAIIPRFPDDPKSRLMQSPSGSDGYISIGTFWELAAIAEESGAGKITGFFRVTEEKEEEVKEEEESQESHEDPVSRSSSTGETKTKGTAEESSRKHLKGSTRNYTKAINFLLDLNFSTLERSRESTKQWKEEVNKWTLATKVGESESESVESSDRSWIQQLTVSIDLPRAEETKSLHVVEAAPVTAQQSPQTPTVHTLNSGLIKRKEPVSTQSTPSAAVNVLNVNLIKRKAPQSTDDKAAAPSSADTPAVNVLSPGLIKRKIPQTSEVPVVNVLSPSLIKPKAEAVASSPTTTETTPQTTNTSSSTPAVNVLGSDFIKKKRRVDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N379</accession>
    <name>A0A9P6N379_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001565</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000136">
        <property type="protein sequence ID" value="KAG0021857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N379"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="256"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="311"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="372"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="108"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="186"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="259"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="311"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="326"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="393"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="415"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0021857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="442" mass="47696" checksum="B3462C554AD9651D" modified="2023-09-13" version="1">MSTPGTIDKKRARPMEEFSPARKKVASELMAFEFQSLSLSNPAGSARSVAPAQNGSDIQGSMPQRHPPVQQESNQETQLHHRPLDQERGQYQLIDIEQHQHQHHQLQQHHQLQQQQQLQQQQQRARAKSSPVGPGTLLTQEREVRLGQANSHQGLPSPPLPLPSISVSQEHEYRHYATLLHEPYSSSAATSSTPSSNSSFSPLTPPISPPPSGSSTTVDVTMMDEGMTDIPRTMTQSSYQESFNVSAVPATTITTAELSSSSSSSSSSSSSPSPSQPPPTSEVKVLNMRQRKWNSASKKWQEWQDVQATHTPHLQSPTPYTSGMQATSSASPGSTGTGSAVVAQTVSDHWAGEYENVIPDATYGMYPQSNGLGRQRSFHGPGEKSSIELAGDSNVNDTRNSYAPTPPAAGPSPAVTNVSIPNASTPKGESCITPFRVVSVIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3C1</accession>
    <name>A0A9P6N3C1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aldehyde dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ALDH3A2_2</name>
        <name evidence="7" type="ORF">BGZ80_008590</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000047">
        <property type="protein sequence ID" value="KAG0023676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3C1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006081">
        <property type="term" value="P:aldehyde metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012394">
        <property type="entry name" value="Aldehyde_DH_NAD(P)"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43570">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43570:SF16">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE TYPE III, ISOFORM Q"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036492">
        <property type="entry name" value="ALDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="6">
        <location>
            <begin position="30"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="48"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="207"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR036492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR036492-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0023676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="417" mass="46591" checksum="5437929F50C0A756" modified="2023-09-13" version="1">MSVEYTPTSSIPKARKQLECFHSKHRRLPETIVSDVRASFLTHRTQSLEFRKEQLRALQRMVSENQEEIVEAIKADLNRNKDFEVPSMLATCEYFINNVESLTENHKVKGEKETFGLILEPLAGAIAAGNVAVVKPSEHSENSASVMTRLFKKYLDPSVVSVVNGGVEETTVLLEQRFDHILYTGNSEVAKIIMAAAAKHLTPVTLELGGKCPVVITERADLVDTAKKIAGWKTLFCGQVCVTVDYILCPKHLQNELIQNVIGIWKHLFGEDIKASEGYPKVINKRQHQRLERLLEKVKSQNTIVFGGRTDAEKLFVEPTIVTNVSPDDEIMKNEIFGPILPIITCETIDNALEIIGRYESPLGVYLFSDDKELADRDNNLPFGGVGHSGMGNYHGKFSIDTFSHKRAVLIRTQGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3H6</accession>
    <name>A0A9P6N3H6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Histone-lysine N-methyltransferase SET9</fullName>
            <ecNumber evidence="11">2.1.1.372</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Histone-lysine N-methyltransferase set9</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">SET domain protein 9</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="primary">SET9</name>
        <name evidence="17" type="ORF">BGZ80_000815</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-lysyl(20)-[histone H4] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(20)-[histone H4] + 3 S-adenosyl-L-homocysteine + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:64456"/>
            <dbReference type="Rhea" id="RHEA-COMP:15554"/>
            <dbReference type="Rhea" id="RHEA-COMP:15998"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61961"/>
            <dbReference type="EC" id="2.1.1.372"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.372" evidence="11"/>
    <dbReference type="EMBL" id="JAAAID010000118">
        <property type="protein sequence ID" value="KAG0022184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140943">
        <property type="term" value="F:histone H4K20 trimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10524">
        <property type="entry name" value="SET_Suv4-20-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1700">
        <property type="entry name" value="Histone-lysine N-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041938">
        <property type="entry name" value="Hist-Lys_N-MTase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025783">
        <property type="entry name" value="Set9_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039977">
        <property type="entry name" value="Suv4-20/Set9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025995">
        <property type="entry name" value="Tudor-knot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12977:SF4">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE KMT5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12977">
        <property type="entry name" value="SUPPRESSOR OF VARIEGATION 4-20-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11717">
        <property type="entry name" value="Tudor-knot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51567">
        <property type="entry name" value="SAM_MT43_SUVAR420_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="5" id="KW-0158">Chromosome</keyword>
    <keyword evidence="14" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SET" evidence="16">
        <location>
            <begin position="99"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="238"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="441"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="488"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="615"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1082"/>
            <end position="1106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1278"/>
            <end position="1333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1348"/>
            <end position="1442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1457"/>
            <end position="1490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1525"/>
            <end position="1603"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1646"/>
            <end position="1707"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1754"/>
            <end position="1983"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="572"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="306"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="333"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="397"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="448"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="494"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="508"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="1292"/>
            <end position="1303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="1308"/>
            <end position="1333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="15">
        <location>
            <begin position="1360"/>
            <end position="1370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="1423"/>
            <end position="1436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="1472"/>
            <end position="1483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="1654"/>
            <end position="1667"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="1681"/>
            <end position="1701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="15">
        <location>
            <begin position="1771"/>
            <end position="1780"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="1788"/>
            <end position="1800"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="1828"/>
            <end position="1843"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="1844"/>
            <end position="1855"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="1903"/>
            <end position="1916"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="1921"/>
            <end position="1933"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="1949"/>
            <end position="1967"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0022184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="2045" mass="227337" checksum="BD3EBB6814BEE5FB" modified="2023-09-13" version="1">MDLQTLSTLDDLMSDILLDGINLWFQTHKMNKDYRPLRLPTGKVLDIIQRRVIVDRKVPEAVKDLLEIEPIKKLFKTDKEIQDFTVHARRYLNIYLPTAGFEISQTDRYSAVTNKSEACVIANRPFEVGFELRYCAGTIAILNEQEERDLENRTSDFSVIKTSRKGTCLFLGPARFVNHDCDPNCSFMSAGANVIYFKVLKQINVNDEITTHYGDNYFGTNNQECLCATCERLGQGGYKKSKGAAAETPISPTLRPAREGPPSRRLRNRQNVNYYPTLLSRPAAKQNPTQLPTPPKTTSPPVESDTIPSTSGPLTPISQRDPESTEEPEQTEQTEQTEQAEQTDQTEQTDQTKQTEQTEQTEEIVDSLSDTIETNIAADESSYDREQPILEPEQSGQPELEPVQPNLELELEQPRPEVEPEEPEQRPQQQQKESIDNMTAETGRNADSDSVSTGAGSPSFSPKNFRMSIDFLCHSSARAPTLNIPNMAVEDDDNRTQDDISEHESEVVPNNQTPKGTNRTPAKETTEPLRCENCKDAISRHELSPSLTCRRCHRHFTIYGMPWPSRSNQAIVAKLRKAEREAAMKLKAAQNALEAERLKKKKIAAEAAKAAMKASAAALGQPKSTKKKGSKSSKTSTQMSMMGLHYRPPGMVMQYHGEPYAYSLNDQTSEVYNRQRYGAFNMDYGQPLSQDHLRCDFSNIITDDHPFHHAPYVVFVDPQDGEGTNYWWIAVTVPRSQIDSSMPEIGKRDDDTRDPDLIVVRFLEDFKYSVCNISGLKLFHPDQEPYRGYVNTYGRDFIKNLGVKRALAFLNGDVPTELQWRDMSCDNQLSLPEVAMVTRRIEMQIEDEQFRVQQLRDRQLHYQALYQQYQEHPDSLMPGHSLGDFRSQEEMYGQDYYSLEQLRQRQYQQQYQGQWEDQDNQSLLQQQYLQQYRVRFNSEEQALRYLEENDPSTLDRQRMGYIRGVTFQDQIDMQQSGFSYGSQDEDHRLNALQDEVVQFLARTSSSNKPPKRRQGARGLGKKTLAKLFEMKMQQERDAIETAELGGVAPPITQPKRRSRTKAKVADLIQADAADLQEIHPVDNSSRLTPTPVAKKGSKKGSKKSSAITALAPVPLPRYATTPTPAPVVTPRKAPILHKSAIDPAATPIERSATPIESPAYYSFEESGKPKIKKSRSKLSSVIWWKTSVAPYRAARLKPRSENENPQSYCVLPSSIPSRFKSLSNLLKPQQLPETPRSTGDQFEVDYQLLEWRILEGMQDSSGNLGDGSAIKPVRRRKPGVAPLTKPNYSGSKDCDSTDNRCNIDDIGSSESSETLSLPPSCDTSTSSSLLPSTTCSVFGDDDNDIDIVGLGDNEDTHSRPVSRKRSHKRSAPASTPDLSASLMFSDAIIPTAEKDPRISNKRKKTKKNATDKTATAISPPDDAAVASTSATAKSFTMPPNHKGRVTEVDRLQEWTIKGSLPSEGAGTLRSRPLTSTRPEQLQRSAPAKKQIKTELERLQQWTILNSLPDGETGNIEAVLNDKLTTRSGRKRSREQRDGINLTAIEESPSSKRNRPENYPVASTGPAAESATSKGKKKKTVQQPVVNIHGAEPESSAEESSTSTDLAAVLAESKELQQLMQWAIRDSTIPIDLESNVRSVRSRTKAITQDAPTLETSTTEATVPSTTTRIPRARTGTPGDKISSSTAETSKVNASTAGTSETNAKKNVPDTKKIVPRVETIADKPGMVILHIPPFTFLSGILSPFHQDTSVDAITSGSSRQDASTEKTVRVAVKKGRRKSKSIADGSETKTNPTPEQSESNLADCGSDQGVEANDENIGAKVPRATRRSKNEKLIENTEAERTTLDLSQNAANSSAAVDPGTDVSAAEKPIRNTKQSRRRQSAGVATAEEALAIGESPSNKLISSAESSASSSTDSAKGAPVNTNEIGEVAQNTRSKDALRSKNLKAAESTENSPSGGSSLSSSLAANRTRRSETAKKPNTAIPKFKVGDEVRAPAEENELYDARIRAIRDHKKLHDVYEYHVHYHGYGSRFDAWIEEKLLVRHRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3S9</accession>
    <name>A0A9P6N3S9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_000172</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000103">
        <property type="protein sequence ID" value="KAG0022470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3S9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="24"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="43"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="81"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0022470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="125" mass="13682" checksum="4CAE08A96A3BEF58" modified="2023-09-13" version="1">MPEQPPYERKKDGAEPGTKSAIKTGTSTVEPSVTVTTKKRRFSNSSESSRGSQDTQLASSTTKVTSNEKSSASNQHRSANSKKLSSEPSKPLSANQWEKTAFIGDSDGAKRVKFLRLSNRRYTAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3U2</accession>
    <name>A0A9P6N3U2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_011583</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000095">
        <property type="protein sequence ID" value="KAG0022638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3U2"/>
    <dbReference type="OrthoDB" id="2326382at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0022638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="115" mass="12193" checksum="CD4D42BC298E40C3" modified="2023-09-13" version="1">MRLISQNTDEIAAAEAMRGGAIGALKYTTVALFVGGVLQATSPRFAAIATPQKAWLVVAAFLGGFGNGSDTSFTNYERRDREMQIRIAEQKRHDILYGSDAQAKAAAAVSLSSSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N430</accession>
    <name>A0A9P6N430_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Cation-transporting ATPase</fullName>
            <ecNumber evidence="13">7.2.2.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BGZ80_010293</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Membrane</location>
            <topology evidence="1 13">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.-" evidence="13"/>
    <dbReference type="EMBL" id="JAAAID010000070">
        <property type="protein sequence ID" value="KAG0023136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="48943at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015662">
        <property type="term" value="F:P-type ion transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07542">
        <property type="entry name" value="P-type_ATPase_cation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000023">
        <property type="entry name" value="Cation-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000057">
        <property type="entry name" value="Cation-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000057">
        <property type="entry name" value="Cation-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000068">
        <property type="entry name" value="Cation-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006544">
        <property type="entry name" value="P-type_TPase_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047819">
        <property type="entry name" value="P5A-ATPase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047821">
        <property type="entry name" value="P5B-type_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01657">
        <property type="entry name" value="P-ATPase-V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45630:SF8">
        <property type="entry name" value="CATION-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45630">
        <property type="entry name" value="CATION-TRANSPORTING ATPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12409">
        <property type="entry name" value="P5-ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01229">
        <property type="entry name" value="COF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 13" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="312"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="334"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="529"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="565"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1086"/>
            <end position="1104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1110"/>
            <end position="1129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1150"/>
            <end position="1172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1198"/>
            <end position="1216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1228"/>
            <end position="1246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1266"/>
            <end position="1295"/>
        </location>
    </feature>
    <feature type="domain" description="P5B-type ATPase N-terminal" evidence="16">
        <location>
            <begin position="133"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="15">
        <location>
            <begin position="370"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="73"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="706"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="30"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="77"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU362082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF12409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0023136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1374" mass="154422" checksum="CE6B3DE23B721D26" modified="2023-09-13" version="1">MVNTPSYDPLSTPLLDNHVEPINQVERTQEPSFLAQSSRRGSQQLGHLQQDSHGSSNSLPKVLSSRFHQHSVYGDHDDYEDDENEDEDEDENDSSETQPVLMNKSSRSKSFNRRSPRDSAYDRCIQHVHLEEEDIELTFTGYRFLQTWVHLYYIICLMSGGIIFLLGRWMPRRYLSFVAEKCSMNQADSVVVENEWGQMATETVFTKYYGGPIGSVFSPEQMEGDDDEYDAAGQTVLQNMRYFDYQYIRFIYNPLSKTFMQNSQWKDPEWTSAAKCERGLGRETHQERAMVFGSNIIDVQEKTVGQLLVDEVLHPFYIFQVFSMALWFVDDYYYYAGCILVISTASVVTELIETKKTMRRMREMSKFTCNVKVFRSDIWRYIGSDELVPGDVFEMTDSELSVFPCDAVLMTGDCIVNESMLTGESVPVSKIPVTEKALQLLDLSLSNIPSDLARHFLFSGTKIIRARPGAPAPKKALRTDDAEYGMTQAPRGLAMVVRTGFNSTKGSLIRSMLFPKPNDFQFYRDSFRFIGVLACIALCGFFVSTINFIRMGVPLKLMIIKALDLITIVVPPALPATMSIGTSFAIARLKRSNIFCISPTRVNIGGKINCMCFDKTGTLTEEGLDVLGVQCGDSDTKMFGNMLNNVEEVHFAPDSMQDKCTSLLHAMATCHSVKSLGGELIGDPLDLKMFDFTHWILEEGGLGARPSSVSETAHRSGKGQEGGIVSTVVRPPGAKKFNLNEVLTHHPRELSESVSFLELGIIRCFEFVSSLRRMAVVVKKLHNPGMDIYVKGAPEVMTDICLKDSLPSDYKERLSYYTHHGYRVIACATKSMPTLNFVRAQRIKREQVESDLTFLGFIVFENKLKPTTTPVITTLTNARIRQVMCTGDNVLTAISVSRECELINRSKEVYAPRFITGDSATEKSKIVWENIDDSRMTLDPITLTPAVANESYINHGREFPSFTDALNDYALAVTGDCFRWMVDFAPTSTLNRMLVKGQIFARMSPDEKHELVENLQSIGYCVGFCGDGANDCGALKAADVGISLSEAEASVAAPFTSRSNNIECVVKVIQEGRAALVTSFSCFKYMALYSIIQFTTVSFLYTFASNLGDFQFLYIDLLLILPIAVFMGRTEAYPILSPKRPTANLISKKVLTSLLGQILIQGCFQATLFFIVRQQPWYQPPKYERGAKNIECYENTSLFFLSIFQYLLVAIVFSVGPPYRKPMSSNRPFVFITVGLVTLSAAMALFPPEWLSRFMQLLAIPLSFRVFILMMAATNLGLALVSEHYIFPIIASFIGRKLNARKKSKSDQNAFPVAPTSREQARMQIDPMGSTLNTPLMSPVLSEHPGRRDNVKVVNKGTKIYKEVEDEMRREAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N453</accession>
    <name>A0A9P6N453_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CCR4-NOT transcription complex subunit 11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_010168</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CNOT11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000068">
        <property type="protein sequence ID" value="KAG0023187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N453"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030014">
        <property type="term" value="C:CCR4-NOT complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031047">
        <property type="term" value="P:regulatory ncRNA-mediated gene silencing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019312">
        <property type="entry name" value="CNOT11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15975">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15975:SF0">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10155">
        <property type="entry name" value="CNOT11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0943">RNA-mediated gene silencing</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="462"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="541"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="615"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="669"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="476"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="496"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="545"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="635"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="674"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="698"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="709"/>
            <end position="724"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0023187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="736" mass="79091" checksum="1D36E7BDC79F7234" modified="2023-09-13" version="1">MITVPPREIVAFLGNHLDHVLQQTELDFAQNVATNCRFKAGCALMDILNAVESVHELIHTFLKERSKNNAGRENSASPELAPSTPSELVAIALEAESKQVDLQFLEDCLPDVPIEEQIVLGQGWESVGQRRRGDNKEIWDSLNLLDKLDNCGSLSPNVDIDTTGKHPMGVVRRLDFNNVIIDNKPASTTSGTPMQETVAEEEELEEWEIEAEKHFQGSEDVAPAPAISNPKSKKQVDVNVNRQQLNLIMEQASIQPLTFDQEQFMLSQFNADTAKVHIPLPPPETLPGIVDNNPTIAFNLLQYLIQLSSDLDGGDTGIQKSNGSWSGGGRIGKLGAKDSSFSSPEPSIVDSYLYTMTHAKRLTLHSLEVVNRLSAATTLSPQFLHAYIENAIRCCELVEDKVGQARVVRMLCVFLQSLLRNEAITIPGYYHALQSFCVQFARVKEVANLFQSLVEYQREMDAPPPIQTQGPTIRGAQLPQQQLQQASRHQAQSASMPSTPTTDTPQRSSWLANSGSISNVKSTLSKHTSLNGFSAPGALSQFIHPGPASPASSSSSSHQNGGGHSSSQSFSNGSPIGSHFKTHHKHSSQHSSGSLFSSPTVMSASVNAFNTGLGNPTNLTLNGGPGQSSNHRSRSGSTAPTSSTSAPNSASASDSAYDLDAALRASLKDMETRSGSSSSLAGSPGSGSNASRITSNGQQQQQQQQQQQTSHLGSKGLNTLSHLGSQARGRGARRGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4I5</accession>
    <name>A0A9P6N4I5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_009740</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000061">
        <property type="protein sequence ID" value="KAG0023337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N4I5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="74"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="132"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="195"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="208"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0023337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="587" mass="65631" checksum="D1017FC46AAC4D1B" modified="2023-09-13" version="1">MNFLRRKKNDDQPATPAPTSPTSPSGKRTPAVQRVSSVSGSGIAIPPRTNSAGPQSSPNPNTPVQGQGPLNADQQQQFYQQQQQPQQHQQQQQQQQSPPQQQQQPQQHQQPQQLQYHPQQQHLHDSDSVSVLSQQQQQQQQQQQQLHLPPQQLQQMQSIPQPGSYGGDASLQSQGIPFQSYQDQSLHGVNAPGMDNTYDNNGYDNNYASGSPEDQQLAQPIHENGQTDGYYTNTGAGYENNSNALSSGPIQLPPQGTPNGVDGSNGGITNHSNGSGELPTDIRKLQDEIVSWRRSQEASQAKINQLRATLTQKSQENRDLHQSLSQVTQDRLMLQELVHKRDKEMDDLRSKYLNDVRQIRATDDDHSTIEQRVRMLQAAILQLTKSSAGDRAVNLNIEEAQQLVKKRYKFGNAQPYILNMFLEKYIMDTLLEEVFNCPFYVGYSLAKEYASIHNWMIENNFADQAVRFRQQLCFISAKSPVVQAHAVEEATRIAKGFEGKLERLYNNWTGHQKVLDLVTKAIELSLTMRSQHSEITAQLIPAESAFDAEKMVPAHKSKEGGKVKVCVIPCFIDTNGVVVGKAKVFCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4Z7</accession>
    <name>A0A9P6N4Z7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Calcium-transporting ATPase</fullName>
            <ecNumber evidence="17">7.2.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">BGZ80_008346</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">Catalyzes the hydrolysis of ATP coupled with the transport of calcium.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16 17">
            <text>Ca(2+)(in) + ATP + H2O = Ca(2+)(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18105"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.2.2.10"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="17">Membrane</location>
            <topology evidence="17">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="15 17">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.10" evidence="17"/>
    <dbReference type="EMBL" id="JAAAID010000045">
        <property type="protein sequence ID" value="KAG0023721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N4Z7"/>
    <dbReference type="OrthoDB" id="3352408at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005388">
        <property type="term" value="F:P-type calcium transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02081">
        <property type="entry name" value="P-type_ATPase_Ca_PMCA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000039">
        <property type="entry name" value="Calcium-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000028">
        <property type="entry name" value="Calcium-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000045">
        <property type="entry name" value="Calcium-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000018">
        <property type="entry name" value="Calcium-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006408">
        <property type="entry name" value="P-type_ATPase_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01517">
        <property type="entry name" value="ATPase-IIB_Ca"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24093:SF369">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24093">
        <property type="entry name" value="CATION TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 17" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 17" id="KW-0106">Calcium</keyword>
    <keyword evidence="4 17" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="13 17" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 17" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 17" id="KW-0813">Transport</keyword>
    <keyword evidence="3" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="119"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="156"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="310"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="351"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="846"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="887"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="925"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="956"/>
            <end position="979"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="19">
        <location>
            <begin position="50"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00038148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU361146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAG0023721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1060" mass="115197" checksum="729B954370D32BF8" modified="2023-09-13" version="1">MPRDSSSSEPLLGYRNGSSSYEDANTGDFTLTVQDLAELTDPTNPKPPRQLGGIIAICKALKVDPKIGLPSDEAGAVSVGNSDQPRFAARSKAFGRNILPPVKSASFFDLVYAAYNDRTLIMLSIAAVVSLGVGLYEDYGPHHIPGDVRVRWVEGVAILAAIAAVVFTNAINDYQKDKQFRKLNAKKENRFVKLLRDGREQEVNVKEVQVGDIMVLEPGDLLAVDGIILTSHNIICDESSATGESKALKKDPEDHCYLISGSKILDGSGTMLVTSVGAHSFYGRTMMALRQASPEETPLQIKLDSLADSIAKLGMAAAVAMLVTLVVKYFVERAISHNPFPPGGIIFSDMIRIIIQAITIVVVAVPEGLPMAVTLALAYATTQMLKDNNLVRVLSACETMGNATTVCSDKTGTLTQNKMTVVEGMIGMRQFDSHSNAKLWKSETRPEIVDLVIEGIAVNSSAFEDKDENGNIAFIGSNTESALLGLIKSLGASYSTIRSDTNTIRVYPFSSARKSMSTIVESPRGKEPYRIYVKGASEIVLGACSCYIDSHGDTKPLDAETRAKIGMAINEYADKALRTISLSYRDISSSEFKSLSDSETPDVSLTFLGVVGIQDPLRPGVVESVREFAKAGVTVRMITGDNINTARAIAKNAGILIKGGLAMTGPEFRELSKREQTEVVKRLQVLARSSPTDKTIVVRRLQELGEIVAVTGDGTNDGPALKMADVGFSMGVTGTEVAKEASAIVLMDDNFSSILKSLMWGRAVNDSVRKFLQFQLTVNITAVVLSFISAVTSADNQSVLSAVQLLWVNLIMDTLAALALATEPPSADVLNRYPTSKKAPLVTFRMWKMIIGQSIFQIVLNLALLQYGADIFHLKSQDGTMTREHTLTLHTMIFNVFVFLQVFNEFNCRRINGALNVFRNIKNDMIFIMVQVFVVVGQVAIVQFGGEAFKTTPLTLGQWAVTVLMGSLSLPVGVFLGLLPRRLIPEACMPNEPEEYHQALINPARLHWEGAANQALIQSNFFEAIRKTKPVARSNSSDSLVKDSLWKKSYGTTRTSLDSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N603</accession>
    <name>A0A9P6N603_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uri1, prefoldin-like chaperone</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">URI1</name>
        <name evidence="7" type="ORF">BGZ80_005692</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RNA polymerase II subunit 5-mediating protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000028">
        <property type="protein sequence ID" value="KAG0024145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N603"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019212">
        <property type="term" value="F:phosphatase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23159">
        <property type="entry name" value="Prefoldin_URI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024325">
        <property type="entry name" value="DUF3835"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009053">
        <property type="entry name" value="Prefoldin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004127">
        <property type="entry name" value="Prefoldin_subunit_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052255">
        <property type="entry name" value="RNA_pol_II_subunit5-mediator"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00293">
        <property type="entry name" value="prefoldin subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15111">
        <property type="entry name" value="RNA POLYMERASE II SUBUNIT 5-MEDIATING PROTEIN NNX3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15111:SF0">
        <property type="entry name" value="UNCONVENTIONAL PREFOLDIN RPB5 INTERACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12927">
        <property type="entry name" value="DUF3835"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02996">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46579">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3835" evidence="6">
        <location>
            <begin position="640"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3835" evidence="6">
        <location>
            <begin position="727"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="155"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="352"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="526"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="594"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="706"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="100"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="179"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="214"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="259"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="295"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="352"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="526"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="553"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="715"/>
            <end position="731"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0024145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="763" mass="84193" checksum="2259FAA235DB867F" modified="2023-09-13" version="1">MDRSKDKVSEAEAAELAKYFSKFSAALTQLEEEMARWKNYEEDYKALKTTLLDLPKETSHSVMVPIGSLAFMPGKLVHTNEILVMLGDNWFVDRSATQAAEIVDRRMEFVQENITKLQAQEEQIRTKSGMAPGLLGGQEYNEEGLPIVEITEPYFSDDEEGNDGKKSAQPAPLPFSQKTPKEQAEDRAILERIAELEREDEERERRREAGEIVTSDEETESDDEPVDYDDEESEDEFRPKALDSDEEYEEEVWEHSGNEEEEDEEEELVEQQGVSPKRSVRFADQVARATKPKSKTNTSNNQSASASATASTKPKSPSDLFNLMKAKQQAARSSALTDQIVTMDNLESTFASMTTAGSSSRLSETPLIEEVTKPEPAPLKSALKPPRKKTSLFKQMRAQSSAAEPINATPTVVAPTVVEPKVSLDIQETPPKKMSKFAMERAAAAGAGAATTAGMSKGTKLPENPAVGGISEQVFERNISTPPTPKKATAPGVFEVVERNAPAPVKENKAAEPQSIVGIKDIIENTFTKPSSSSSPIKDAEPTRAGRKKPSLFRQQQHQTTSSYLEPEPAIPGSSVVEVGEDVEEYQSPRTIPPVVSARSKASSGSILETKEPPKATGSTMRTIPIVASSKLKDTALMKGTVVEHEEVEPIDEDEFEDDMLMRQVVSEYQERRQAMIAKHGAFNREGIEQLWEQQVVIPPEMIIPAPQIESIEDRGDDVEEDEGDDDEAEPENNVIVDDRNLPPKKLSLFRAARLSGTLAKQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N6Y9</accession>
    <name>A0A9P6N6Y9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NAD-specific glutamate dehydrogenase</fullName>
            <ecNumber evidence="4">1.4.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">GDH2_1</name>
        <name evidence="6" type="ORF">BGZ80_000011</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">NAD(+)-dependent glutamate dehydrogenase which degrades glutamate to ammonia and alpha-ketoglutarate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>L-glutamate + NAD(+) + H2O = 2-oxoglutarate + NH4(+) + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15133"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.4.1.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the Glu/Leu/Phe/Val dehydrogenases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.1.2" evidence="4"/>
    <dbReference type="EMBL" id="JAAAID010000001">
        <property type="protein sequence ID" value="KAG0024883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N6Y9"/>
    <dbReference type="OrthoDB" id="184415at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004352">
        <property type="term" value="F:glutamate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006538">
        <property type="term" value="P:L-glutamate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006096">
        <property type="entry name" value="Glu/Leu/Phe/Val/Trp_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056365">
        <property type="entry name" value="NAD-GDH_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016210">
        <property type="entry name" value="NAD-GDH_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055480">
        <property type="entry name" value="NAD-GDH_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11606">
        <property type="entry name" value="GLUTAMATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11606:SF24">
        <property type="entry name" value="NAD-SPECIFIC GLUTAMATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00208">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23147">
        <property type="entry name" value="GDH2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23152">
        <property type="entry name" value="GDH_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000184">
        <property type="entry name" value="GDH_NAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00839">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0520">NAD</keyword>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal" evidence="5">
        <location>
            <begin position="658"/>
            <end position="922"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR000184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0024883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1022" mass="116500" checksum="D144A0DC36E505BC" modified="2023-09-13" version="1">MANLLTPGYVPGQSNLPHTVKNTSGYIENAFPGKEEQMVQVTEYLSEKAFIPAALAQNEVSWFYGNLGIDDMYFASESVESIANHIMALYGAKIFAYTKNDNGLDINLERETEEGAVYIHTSRPGVSQLYGPQHEKRIDSKYLDVSNTERAYRLESYRSKGTVSSSSSTQLRTYFVRQCSFVNPTPTKEEENDIRKTADKSFLEKATENTLDIYSSLIKLALSRTGPVIEMFEVEGSRERRLVIAYKQQTTQSFFSAISDLYHYYDLYSTRKYVEQFSNGITIVSLYLNQIPKSTAPPIEHSIHQIIKEASLIYCLPTTPLQSFFQTSKLSVQESIYGYIGWIFAQHFLNRLGNEYTSLVNILDVNNATHQDVLTKMKKRLRTDTFTRDYILEIIKTYPELVKLLYINFAMIHYVNPAVNSLKPTLSYQRLRTDNILTDEELYEKIRRTTSNSHELMVFESFLIFNKHVLKTNFYQPTKVALSFRMDPSFLPEIEYPTKLFGMFLVIGSEFRGFHLRFRDVARGGIRIIRSRNREAYSINLRSLFDENYALAATQQRKNKDIPEGGSKGTILLDVNQQDKPLVAFEKYVDAILDLLIQGQSPGIKERIVDLYKKPEILFFGPDEGTADYMDWASAHARERGATFWKAFTTGKSQSLGGIPHDTYGMTTRSVHQYVLGIYRKLGLKEENCSKLQTGGPDGDLGSNEIKISKDKTCGVVDGSGVLYDPEGINREELGRLAENRLMISNFDITKLSAKGFRVLVDEVNIKLPSGEVIDDGLAFRNNFHLNPMVACQVFVPCGGRPESVDLQNVGRLLDHENHPRFKYIVEGANLFFTQEARLRLERAGAIVFKDASANKGGVTSSSLEVLAALAFTDDEFAEHMQVTESNIPVFYQEYVKEVQTIIERNAQLEFEALWREHLRTKTPRSILSDELSLAIVNLNENLQHTSLWDNVPLRKVVLEEAFPNLLLKKIGLEALMKRVPDNYVRAIFGSYLASRFVYKYGTEPSQFAFFEFMTPYFSKIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SQP2</accession>
    <name>A0A9P6SQP2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008718</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004827">
        <property type="protein sequence ID" value="KAF9992088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SQP2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9992088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="183" mass="20134" checksum="3FBFB13FB9DAEA23" modified="2023-09-13" version="1">MGCSPARNSTTTTSTVTNLARVVAHTTPTQDVSASASSMRRSQLIRDDEDVTALIAEQEEQARAYRKFQQEQESITPELDGEANESVEDTGAESDDELQSVNEQAISVSGRKTPFRGFTPRSEHSINLLNAMLLMSPFDKANGPTVPERRQRVVDTLLESGASKAWNGVLPFPFLLGVTIFWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6STV1</accession>
    <name>A0A9P6STV1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_006308</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003104">
        <property type="protein sequence ID" value="KAG0000767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6STV1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050349">
        <property type="entry name" value="WD_LIS1/nudF_dynein_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44129">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN POP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25173">
        <property type="entry name" value="Beta-prop_WDR3_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="41"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="83"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="125"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="167"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="209"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0000767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="341" mass="36655" checksum="85AE21056975BA47" modified="2023-09-13" version="1" fragment="single">GHIGSIRGVAYSPKGDQIASGSEDSTVRLWEVDTGKCVHTLQGHSHVVASVVYSPKGDRIASGSYDDTVRLWDVDSGECVHTLQGHCGIVWSVVYSPKGDQVASGSSDETVRLWNVDSGKCVHTLQGHSGIVWGVVYSPKGDRIASGSHDSTVRLWDVDSGKCVHTLQDHSGRVYSVAYSPKGDRIASGSEDNTVRVWDVDTGECVHTLQGHSGAVLSVMYSPKGDRVASESDDKSVKLWNIETDQCQAIISDFSSDVSSIALESNSGTPCLETGSLDKSVRCLGITKEGIEHKAVLCWSSSHKVPTVHDLSFEDVQDLSSVNRELIIQRGALIPRPLPSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SUB3</accession>
    <name>A0A9P6SUB3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_005789</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002849">
        <property type="protein sequence ID" value="KAG0003469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SUB3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0003469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="72" mass="8567" checksum="B12270A2008CFFC9" modified="2023-09-13" version="1" fragment="single">MWRRIEILKLIENLQVKQDPQNQDFTEFLLRIGDDKVPPVETGVYKDYVRIPNEYIFEPPVNPSNYPDKSSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SUW5</accession>
    <name>A0A9P6SUW5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Golgi apparatus membrane protein TVP23</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">FAM18A</name>
        <name evidence="9" type="ORF">BGZ80_005398</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">Golgi membrane protein involved in vesicular trafficking.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Golgi apparatus membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the TVP23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002663">
        <property type="protein sequence ID" value="KAG0005734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SUW5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008564">
        <property type="entry name" value="TVP23-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13019">
        <property type="entry name" value="GOLGI APPARATUS MEMBRANE PROTEIN TVP23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13019:SF7">
        <property type="entry name" value="GOLGI APPARATUS MEMBRANE PROTEIN TVP23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05832">
        <property type="entry name" value="DUF846"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="113"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="142"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0005734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="203" mass="22655" checksum="06B01DC83DA0201D" modified="2023-09-13" version="1">MGMNTLEPDLEAGGQPSILKQSSHPVCLIFHFLFRVAAICIYFFGTWFTDNFVLIFVLCVLMLVFDFWTVKNVSGRLLVGLRWWNENREDGTTTWLFESRDPSRPLNPVDSRLFWTGLYVAPAIWFAFGIICVLTFKLTWLLIVAVALALNFANVIGYTQCDKDAKQKWATGFASNMLGGSGAGGLMGGLMSRGITRMAGSIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SV86</accession>
    <name>A0A9P6SV86_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcription factor spt20</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">SPT20</name>
        <name evidence="3" type="ORF">BGZ80_005188</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002577">
        <property type="protein sequence ID" value="KAG0006645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SV86"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021950">
        <property type="entry name" value="Spt20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046468">
        <property type="entry name" value="Spt20-like_SEP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13526">
        <property type="entry name" value="TRANSCRIPTION FACTOR SPT20 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13526:SF8">
        <property type="entry name" value="TRANSCRIPTION FACTOR SPT20 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12090">
        <property type="entry name" value="Spt20_SEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Spt20-like SEP" evidence="2">
        <location>
            <begin position="148"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0006645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="511" mass="56899" checksum="9F9EC3F85488BBAE" modified="2023-09-13" version="1" fragment="single">MVTAIEHHSNQGSQYGASSMNGSPRGGPKSPALNSPNGMVSPSRGSSGHNKKSRNLSLQTKIHGGQFDTIMSESPRTALSSPNGVGSLLSQDLSVNTPRSTKRSIDEVYSSRKVRYLISSLKYYRDATVCSELFIRLGIDDLLEKYKSSPASFVIHLYETHFKFENQDGVFLFNSPMKIFLKCIQERTMPSGLLDIIKSAQCPYYEGRLIVEIVDHRTKVKNEGVESTKRVVLTPTPGTLWADLSLLHEESGERWSNDMMLDVESKILIATEEPLCLDPSPMVTVLSNEICYNQTSATQRTRKRRKWNSLEREQEAARKAEEDKLMSMMDEKSTVDFQPNFGRLAFLKEWRQKKKMEETQPIPVLDPKKSKVKRQEMSVLPDGRKIVRTIRFEQEDKKRNYKMYFMFNIMQCPDQSFEAIMRYGTAPDSAVNGGIRRFTLGPEQCADAYVQSLKSMYFTANSLISDTTPTSTNTTARANAAAAAAAAAAAAAAANTAPGIGVNTNANMAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SVC5</accession>
    <name>A0A9P6SVC5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005086</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002528">
        <property type="protein sequence ID" value="KAG0006931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SVC5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="391"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="894"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="391"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="894"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="911"/>
            <end position="939"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0006931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="939" mass="107778" checksum="8D208400F088A6EA" modified="2023-09-13" version="1">MKLQPDTMQDEQRAEKAVDDILKLFGLKLVGPFVTPGLQMLQALYGRIESEGKASIETNRGSRDNREVERGLTVDYSRYFSEIRPEYWGYMHFSEMIRLRKLPEIMYGSGLYDSFDWWIGANNGVIESSITSGVGTMAGATMEVESDEMDEEHTLQEQCHPVYTDKLQEALMKLWFHCNHDYITSFTFDIYNADFYLPFATKMRKLQALNFPKPRSVLSDNLTESAVLFIKQNQETFSRKSQLDVEFDSGWFMEEGDYPRDGIDEFDMFSVDLATYNERMQKRRRHALNFMKPMLSILEAAGLPTSMSVEEVPFFYDNAHAIGTDRLLDFTDTDQSRFEQGEGPAMEAFLRRCGNLKTLCLGVGSANMLSWAADEALRDLGLTRSALSGFVSNSDSCSASEQETKSSTPPRSSKKEMSNKHRNNQQQQKHTSLIRHSMNLLNSLRSLKLFSDHSYRSAIHTMNDAMVAFAGPIKEIELRGYYYINEDSARIPGSLMKEWDRNSFKLRNNPWANQIGEWPILLPQLSKISVILRNVACIQVGSFSQCPNLQVLYLEFGGLYPSDRDVGPYGELYDIEPVPKPDDDVIQADLDDDDTVTQSQWLQADVDRTLFPTWNLPNLVVLRLKGLPAVRFDFASLSSMKNLEHLELDAAKRSTRRGTERYDMGEYKEYQQQIWNKRLSHQHPSDQDIRRKRGRSNTGTVKWPLPALKEMILRGPPASMFHLNWIRECPKLVALSVNSDDDVLDIRHNIFFAADLNESRNRRDKGRSSHIDHPSPFLMKVTFNGEWTFSEETLRHFLTVHAPLLFEFYLDHDPANLSSFQLFKAIHDIYDSNNQTLSGSNLLLSKVNSNCSLDSKEAEKLGLIEFTEKMYRYEGKLRIYKTSSGEFVRQEQYERVCSRDRTGGKDREGSEDSNEGDDNDDSDDSDNQADQTDQAEDNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SVR1</accession>
    <name>A0A9P6SVR1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004733</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002384">
        <property type="protein sequence ID" value="KAG0007369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SVR1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="211"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0007369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="220" mass="24669" checksum="2D941F8CCE7B288D" modified="2023-09-13" version="1" fragment="single">MSSKKAGLPSLNSINKKDGLQPVKVQRYRAGQAPEGYVDPALESSDEEEDENDASKTRRDGRSKGVGGATGGNMSISQEDQQPRVAYKILNIERMTKERQMEKKSQSQSIPDIPAGASGDRRLARLQAIQMEDRRSRGDVRSRRGRGGSDEDEEGGEEEEKEEEEDDEEEAALRRRKAARARAMREEAEEEELWGQGEEEEEEEEEDGAGRKGKSRREGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SVT3</accession>
    <name>A0A9P6SVT3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Sel1 repeat family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004617</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002337">
        <property type="protein sequence ID" value="KAG0007475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SVT3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0007475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="264" mass="29510" checksum="5497BBAFD9129E15" modified="2023-09-13" version="1">MEWYLEGANTGSNGAQHIIGFMYFHGLGVAEDYSKAMEWLLKSVSQGFSLSQRQIGIMYGNGKGVPRDHSRAMEWFLKAANQGDFESKTRIALMYADWNEVPVDDSKAIEWLSNAAEHGLAVPQYALGCAYKNGRGVSVDYSKAMEWFLKAANQGDADAECAIGVMYLHGEGVRRDFAKAATWLRKAAKQGNAKAQFNFGHLYYAGDGVPEDREKALEWFLLAANQGERSAQYRLSHMYYNGIGTPQNIALGEEWNRIARNNPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWL2</accession>
    <name>A0A9P6SWL2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Prenylcysteine lyase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_004001</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the prenylcysteine oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002096">
        <property type="protein sequence ID" value="KAG0007974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWL2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001735">
        <property type="term" value="F:prenylcysteine oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030327">
        <property type="term" value="P:prenylated protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030328">
        <property type="term" value="P:prenylcysteine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.660.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.405.10">
        <property type="entry name" value="Guanine Nucleotide Dissociation Inhibitor, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010795">
        <property type="entry name" value="Prenylcys_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017046">
        <property type="entry name" value="Prenylcysteine_Oxase1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15944">
        <property type="entry name" value="FARNESYLCYSTEINE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15944:SF0">
        <property type="entry name" value="PRENYLCYSTEINE LYASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07156">
        <property type="entry name" value="Prenylcys_lyase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Prenylcysteine lyase" evidence="8">
        <location>
            <begin position="73"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="domain" description="Prenylcysteine lyase" evidence="8">
        <location>
            <begin position="373"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0007974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="420" mass="47586" checksum="61FF0735C984589A" modified="2023-09-13" version="1" fragment="single">QSDKIGGRCTAFRLQSPGEEDEYIEVGASIFVKANHNLVDASKKFGLKVKQLDDEMLAIWNGKEFIFEEKKNQLQRLLKTTRDNFLKSYQSPEAFHTISDFAQRFKLDKVASVFSNHFLQDNNIDDQYNTEVVEVATRVNYGSNLHEIHALGALVTMAADDALQIQGGNFQIFEGMVGRSKANVRLGTKIARIQRLESKSNDTESRFEITTTTGQKEIFDTIVIAAPIQSTDIKFDFDMPPVPEVKYRTIYATFVRGHVNPAYFNVASVKDFPAHILTTNSGAEFISLSIQTRLKNGETVTKIFSQDPIQDELLDRLYSNRTWVKSKLWKAYPHLEPLPLTDSDPLAPLNEEKLPEQQQQQQQQQLSQAAWGKVEVVPGLFYLNAFEPLISTMETETIAGKNVARLVRDRILGYCPVEKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SX80</accession>
    <name>A0A9P6SX80_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_002484</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001614">
        <property type="protein sequence ID" value="KAG0009346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SX80"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="213"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="215"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0009346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="266" mass="30971" checksum="AB3E9DC56BBDF3B0" modified="2023-09-13" version="1">MIEGKAVVGVPLPIEDMKTCELILQTFLEWEELYTKQPSPFTINLSESFWGRKSWPILMGLLHVVDGIFLDEEKMGLDSSRRRNEGRQWTPESKVSRKRIGRKLDLIARDMVEMKDWLVVERMKEWDEFSTKFLKESGCDLIRETHTIMRNRLQDAKNTQFKHEACFYGIYTGDEYYSLSMINTIEAYRRPEPESDVDWIYGNSREGRKIENTLASSPIASPSPSDYFEPDTYIPSDESFGPIEEDGEERAAEEDFEDLELYLSSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXH5</accession>
    <name>A0A9P6SXH5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_001832</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001429">
        <property type="protein sequence ID" value="KAG0010045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXH5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="193"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="245"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="308"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="438"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="538"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="308"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="326"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="438"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="545"/>
            <end position="557"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0010045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="603" mass="62417" checksum="57B37C059556EDE9" modified="2023-09-13" version="1">MDPSSNTARPTTTTDPVTTTTTTDAPTTVPTTVPTTVPTTVPTTIPTTVPTTVPTTVPTTEPTTATTTTTSDHTTTTDLPPTITTTTDATTHAITTTTTTTTQPPTTIFTTPSIKTTTKTTTTPYTTHYITTYTIITITTEVPKTTRISGSVTTIYITETTTTPTPTVIPDPNQPPPATLIDGNNEGRSLQPWQITLIVVACFVLSVAIGAVVIVGQIKKRRKSRADSGLFGDGFGARRTTTTNANAAAGGGGGGGGGGGGGSVGDSSVFGSEFAESGGGKSNRTLIAPSAAGGIRWSNLFKFPRHWGSSSSGRYRGGTSQRNSGLSGGNANGVGSGGVGGPGGLWLMEENDSHQDDNVVAAAAMHPVSYQNDFHLGGGGGVGESGGGYGEGSYPVDLLGAQQQQQQPDMAEIRHAHYRQQEQHPMNSAMYPVAAGLSPTRLSPTRLSPSLSHPEGQSHSPNGGGSSRSGVNTIASSSQHMLQPFYEERLLDSSDYVDGVGYGHNQSQRQSIETDFLTVSSGPESRGEGFGVGGLDMIGRDGSRSSENAGPSRNRTSVFVDPDQLESNAVYEHIRAGPQALPTAPEEPDSHENTLPTTAPADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-10-08" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXK1</accession>
    <name>A0A9P6SXK1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Autophagy-related protein 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">ATG4B_1</name>
        <name evidence="14" type="ORF">BGZ80_001757</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>[protein]-C-terminal L-amino acid-glycyl-phosphatidylethanolamide + H2O = [protein]-C-terminal L-amino acid-glycine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine</text>
            <dbReference type="Rhea" id="RHEA:67548"/>
            <dbReference type="Rhea" id="RHEA-COMP:17323"/>
            <dbReference type="Rhea" id="RHEA-COMP:17324"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
            <dbReference type="ChEBI" id="CHEBI:172940"/>
            <dbReference type="ChEBI" id="CHEBI:172941"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:67549"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C54 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001406">
        <property type="protein sequence ID" value="KAG0010134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004197">
        <property type="term" value="F:cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019786">
        <property type="term" value="F:protein-phosphatidylethanolamide deconjugating activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035973">
        <property type="term" value="P:aggrephagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000423">
        <property type="term" value="P:mitophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005078">
        <property type="entry name" value="Peptidase_C54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046792">
        <property type="entry name" value="Peptidase_C54_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22624:SF49">
        <property type="entry name" value="CYSTEINE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22624">
        <property type="entry name" value="CYSTEINE PROTEASE ATG4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03416">
        <property type="entry name" value="Peptidase_C54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0072">Autophagy</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 14" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Peptidase C54 catalytic" evidence="13">
        <location>
            <begin position="1529"/>
            <end position="1807"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="168"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="332"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="560"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="743"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="795"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="929"/>
            <end position="963"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="979"/>
            <end position="1027"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1053"/>
            <end position="1149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1391"/>
            <end position="1512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1839"/>
            <end position="1878"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="29"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="170"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="332"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="351"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="361"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="377"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="440"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="574"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="601"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="617"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="648"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="795"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="820"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="998"/>
            <end position="1013"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1086"/>
            <end position="1098"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1106"/>
            <end position="1119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1128"/>
            <end position="1138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1410"/>
            <end position="1472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1478"/>
            <end position="1512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1840"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1860"/>
            <end position="1869"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF03416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0010134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1972" mass="217804" checksum="9253FD688DB9FA6F" modified="2023-09-13" version="1">MDSFQQPLFNINVSPSPPSSPLRDRRPSFTRSRSQQTLHDPSRHFTTVSSPTRTHPALVLDPATGIRAPPTSMPAMHTGPPPSPATVSGTTAASAFATLQKVYHSKEDIGFWSTLYSQHHVHTRQDYQALQDITSAPLAPSAESCLKTQGPIKVWQVLTKTTLENDAETINNNNNNNNNNNNSNSNISSSNNSSQLQQSFPRRGDSRQYPQYHFERLPIKVQTSASALSPHGHPFSIVFFFTVESTPTTLWYLESAFTQSTTVHEHMELMGTFQPNDSKDPMSFYIYETHAFNVDQPLQEDTMLDIHVQSPSGTIYAKFSYTFIRESRNSTTSTASSVMSITPTSPQAEMSSSSSSSDSNRNGDDNRNNDTNDSSSVVAQQKTQDQNVEPLSPTLNKSNSIPLSPLDSYDVVEYDPPKSLECIPQQQQQQKQQYHHHHQPYHESILEDKDCTAQSSPHPEPAAGTPSTSALVRPILEENSGDEDDSQELIAGSSFVEEPDAGEHFMQATSEFFSKVGYWIYNSRVVQYIARDDRIRVKTIFPTEDIWILGIRYSLEPTEPTCSLPETSRSRKLSSIQQQTSTSRTGDSKSSIVGSLGPGTDHNRDSKRGWERKFAHASTSPRAMTDNDSIFTFTSTAEGSESGVSRSRSKERQLERQREKEQAKAKKMAQIRERELEKEEKAREKARLKDQEKLQKLKLKISHPRFDPNNLRDGTKDLSEVSMSDTKDQHSCAHIEGIRKSRSIHGYNSEDNPNVGLGLTTPSGEPKQSVIRRMRSISILQKVPNALDALAQKKSLHESQPRVLHDRTHQPRSQSVSNISVFSQRSTGTSSSLSHDGPLKQRPNSPPPLSPMKATMSVHEALTVGPKPTALLKLSHLNLSQKKLPDLPPSDPDIPNIPAYPYQDSTPTDQSDLGAHGYAYASVPIPYVSDEDAEESTKDSKSSRRRMTISGIFSKEPKPSTNSGLAVLKTLVNASKISLRPKAEDPMPSQKYQGPLSVGSTTTGISFGPQPSTGKDRPPSSKKGGVTKNMQHWIERRLSSNNLHQQTFVAATDEPVPPVSKELNMSPPSSPLTTRVDESDVLPQSPERQQANGSQRQQLRSRKKSSIFSTTSSSSAISSPLSTFKPGSPQSTASSNRTFGGARSPIGPLDQEEDVCEAYVAFATSPQFAHSPALLLEGKTEKGVTLGLNLDHPVEKLPCAIPIQAQDPPSSKDIVILPPLPPESPSETFVLLNQERDSSLVSLERDLEGSVLVSVLDADEVSSPPILNDSNQEILEDVDPIRTENQRLFKQLAAFSNDKSESISNLRSEWESLWPSKLEVVQSTRKDSADFVHVQKTNGTRSPILKENLTLEERERIRKIGSAYVKVKSPNLEIIAPQPKTPALLQNQALNKGDEGDIPGLSSTERLEPSPKSSSLLQPPPLLTTLPSQASPSSPDPSLSKSWRAISPPSFVSSPKPSSTRSVSVQVSNSTTNKVEDQSTVSGNTDVSSGGSPINGEISSTLQPSTAHLSDKPVSSLNLSANQRTLLLFMSDFRTRFWFTYRKDIARIGPSVYTSDAGWGCMMRTGQSLLAQAFSNVLLGRDWRANSRMSEESAMKYRKIISWFADEPERPYSIHKIAKSGLYLDKRIGEWFGPSTVAHALKRLTEQHTSCPVTVMVPMDITVRFSDIQCAACEGHGANVSTGPDRAGLKANHWKPVVLLMPSRFGLEKLTERYVGNLKRLFRLPQFLGIAGGRPGRSLYFIASQGNELFYLDPHFVKPRATQEELSNAPSTSYHCGVIRAMDIMEMDPSMMLGFMIHSAKDLIDLSTRLKNEMEKGCQLLSVIEDVSLEFQDDDCLGTKDQTPASAEMQPESTSCETTLGKEHKHKSDQAPNVDRGAEVHVPQADSLGTVDLMEGYHHTQSYSPPQSKRVMKRITRTLKSNVPVPESLDKETVPHVTTNLYHHQHTIQNGDHVHDDDNLSVRSFDSDVSIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXQ6</accession>
    <name>A0A9P6SXQ6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PAS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_001712</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001398">
        <property type="protein sequence ID" value="KAG0010166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXQ6"/>
    <dbReference type="OrthoDB" id="411251at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAS" evidence="2">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="283"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="336"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="367"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="289"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="371"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0010166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="440" mass="50355" checksum="A79DC33431607508" modified="2023-09-13" version="1">MDLSDKCRFLWASPGIEDVFGYDSDEVIGMSAIEMVMSTDVHNVYDAVKENIMNDLVSSQLFAKYRHKDGHPVYIHVVFSMCYDMIVSHVILVPPPEEGYRQPSRAHSRAMTRLVGVKKETSLFQNFTVQAIRLLPREFARMKRHHNAFKANNTWDATSLEPEARVCLLLNRYTRSLIVMYASAVCDKVLHIDPDKIIGKSILLFIRSDDLGLFVEQLDIVKRESSIINMRLCFQSPNLLNEVPCEAVFVGARDAVIAVIRRYKPFVRKYYLGSREQYESSTKHAKQYSRLTSPPSSSSIMVSSMSSRDSAWNSSAVKKSTLNRIKIYELGDDNKKARPLSSLPDDDPCLVRDSSSLSQHPVLKEVIFRSDDEDEDEDEDDYDVDDGDVDDDDKGDYEDVSYTAKYNQEIDESGLEHMDIRECDDMDIEYNKQESGYRTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SY57</accession>
    <name>A0A9P6SY57_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ribose-phosphate pyrophosphokinase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">PRS1</name>
        <name evidence="2" type="ORF">BGZ80_001706</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001395">
        <property type="protein sequence ID" value="KAG0010183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SY57"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017101">
        <property type="term" value="C:aminoacyl-tRNA synthetase multienzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004827">
        <property type="term" value="F:proline-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006433">
        <property type="term" value="P:prolyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004499">
        <property type="entry name" value="Pro-tRNA-ligase_IIa_arc-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43382:SF2">
        <property type="entry name" value="BIFUNCTIONAL GLUTAMATE_PROLINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43382">
        <property type="entry name" value="PROLYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0010183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="131" mass="14786" checksum="6990BC48A1A76CC7" modified="2023-09-13" version="1" fragment="single">MSAEGSSSAPKANKAAPKVNKMAPKAKKAAASTGAAQIGIEYKKDVDFPNWYQQVVTRSEMLEYYDVSGCYILRPWAYRIWQEIQLWFDGEIQELGVENSYFPMFVPAKNLEKEKDHVEGFAAEVAWVTKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SY66</accession>
    <name>A0A9P6SY66_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Signal peptide peptidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_000796</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase A22B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001175">
        <property type="protein sequence ID" value="KAG0011284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SY66"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098554">
        <property type="term" value="C:cytoplasmic side of endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098553">
        <property type="term" value="C:lumenal side of endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042500">
        <property type="term" value="F:aspartic endopeptidase activity, intramembrane cleaving"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033619">
        <property type="term" value="P:membrane protein proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01653">
        <property type="entry name" value="GATase1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007369">
        <property type="entry name" value="Peptidase_A22B_SPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006639">
        <property type="entry name" value="Preselin/SPP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12174:SF23">
        <property type="entry name" value="MINOR HISTOCOMPATIBILITY ANTIGEN H13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12174">
        <property type="entry name" value="SIGNAL PEPTIDE PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04258">
        <property type="entry name" value="Peptidase_A22B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00730">
        <property type="entry name" value="PSN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="17"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="151"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="180"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="254"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="299"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="329"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="400"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="58"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="406"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0011284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="427" mass="47187" checksum="F0BCBB34C4443E84" modified="2023-09-13" version="1">MATRNVTSPAVAEQGLYVAYAALTTMAIVPIFFGSFSSLKKWKNPNVKKRVTKRQIDESDESEEDEPLESVSAGDAYMLPVLGSVALYGLYLASVHLDKTYVNYALTTYFAFMGVMATAQVGVNTLNPIIKLLGIKIDHWHINLARKSKGFYSASFTIVHLAMIFVSVLLSAFYVATKNWIVSNVFAISFALSAIQLLSLESFRTGIIFLSGLLVYDISWSFGSEAIMSVAKDLDVPIRVIFPRLFFGLPAGQAYKFAVLSLGDIVIPGVFIAFCLHFDQHRAGAKNPELGRSRQFRKPYFAACLTAYVLALGASFYSMHISKATQPALMYLSPACILSVLMTASIRGEMKQVFAYTSEEGLEAIRIKKQARDRKQKLKAQAKAQASRYARVSKLPQVIREESYVTSRSTPEPTSTTPSESTSQEKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYA0</accession>
    <name>A0A9P6SYA0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Golgi Transport</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">GOT1</name>
        <name evidence="8" type="ORF">BGZ80_001514</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the GOT1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001346">
        <property type="protein sequence ID" value="KAG0010399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYA0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030134">
        <property type="term" value="C:COPII-coated ER to Golgi transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000137">
        <property type="term" value="C:Golgi cis cisterna"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045176">
        <property type="entry name" value="Got1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007305">
        <property type="entry name" value="Vesicle_transpt_Got1/SFT2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21493">
        <property type="entry name" value="CGI-141-RELATED/LIPASE CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21493:SF9">
        <property type="entry name" value="GOLGI TRANSPORT PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04178">
        <property type="entry name" value="Got1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="69"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0010399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="126" mass="13890" checksum="262C8602E17A6992" modified="2023-09-13" version="1" fragment="single">MMWLSDTQKIGVGLTAFGLFFMLMGVMMFFDGGLLAIGNILFLAGVTLVIGTQRTVVFFARPQKIRGTICFFSGIFLVFIKWPIIGVIVEFFGFINLFGDFFPEIVGVLRRLPVIGNVLSAPGISK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYN9</accession>
    <name>A0A9P6SYN9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Needs CLA4 to survive protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">MOCS3</name>
        <name evidence="12" type="synonym">UBA4</name>
        <name evidence="15" type="ORF">BGZ80_000112</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="12">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="12">tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">In the N-terminal section; belongs to the HesA/MoeB/ThiF family. UBA4 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001017">
        <property type="protein sequence ID" value="KAG0012229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYN9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070566">
        <property type="term" value="F:adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004792">
        <property type="term" value="F:thiosulfate-cyanide sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042292">
        <property type="term" value="F:URM1 activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032447">
        <property type="term" value="P:protein urmylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002143">
        <property type="term" value="P:tRNA wobble position uridine thiolation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14686">
        <property type="entry name" value="bZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00757">
        <property type="entry name" value="ThiF_MoeB_HesA_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.250.10:FF:000014">
        <property type="entry name" value="Adenylyltransferase and sulfurtransferase MOCS3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000033">
        <property type="entry name" value="Adenylyltransferase and sulfurtransferase MOCS3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03049">
        <property type="entry name" value="MOCS3_Uba4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028885">
        <property type="entry name" value="MOCS3/Uba4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004281">
        <property type="entry name" value="PRK05690.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953:SF102">
        <property type="entry name" value="ADENYLYLTRANSFERASE AND SULFURTRANSFERASE MOCS3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 12" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="6 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 12" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="8 12" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Rhodanese" evidence="14">
        <location>
            <begin position="357"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="9"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate; for adenylyltransferase activity" evidence="12">
        <location>
            <position position="248"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine persulfide intermediate; for sulfurtransferase activity" evidence="12">
        <location>
            <position position="411"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="129"/>
            <end position="133"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="190"/>
            <end position="191"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="307"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="310"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00075323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0012229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="455" mass="49790" checksum="F15F23D4E3880C73" modified="2023-09-13" version="1">MESTPPVARESLEHKVRRLEQEKQELERQIDALRLEQAQSFKSRAAAAPAPHDLLDRLEKVAKLTNPEIARYGRQLILPGFGIHGQMCLRNCSMLVVGAGGLGSSCALYLGGSGIGRLGIVDHDTVDISNLHRQVIHNEARQGLSKAQSAAVSVRLLNPHCQVVVHDLVLDSSNAQPIIDAYDIVIDATDNVATRYLLNDACVLSKKPLVSGSALRLDGQLTIYNYGGGPCYRCLFPTPPPSETVTNCSDGGVLGVVPGIVGCLQALEAIKIATGMNAQDPPTMTLFSANSSTMFRTIKLRKRKADCIVCGDSPTITKLIDYVRFCGSSATDKTPDIFLIPFQERLTCEGYKNICENNTPHLLLDVREKVQFDICNLPSSLNVPLKDLVGQMDKVKERLGPHADQPIYVVCRRGNDSQPAVKLLKEQRITTGEIRDIAGGLEKWADRIDPDFPKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZ65</accession>
    <name>A0A9P6SZ65_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Altered inheritance of mitochondria protein 41</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">AIM41</name>
        <name evidence="3" type="ORF">BGZ80_011574</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the AIM41 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000949">
        <property type="protein sequence ID" value="KAG0012684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZ65"/>
    <dbReference type="OrthoDB" id="538640at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016884">
        <property type="term" value="F:carbon-nitrogen ligase activity, with glutamine as amido-N-donor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1510.10">
        <property type="entry name" value="Uncharacterised protein YqeY/AIM41 PF09424, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003789">
        <property type="entry name" value="Asn/Gln_tRNA_amidoTrase-B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023168">
        <property type="entry name" value="GatB_Yqey_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019004">
        <property type="entry name" value="YqeY/Aim41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042184">
        <property type="entry name" value="YqeY/Aim41_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28055">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 41, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28055:SF1">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 41, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09424">
        <property type="entry name" value="YqeY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89095">
        <property type="entry name" value="GatB/YqeY motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="214"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU365099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0012684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="289" mass="32070" checksum="6461F919DA19D3ED" modified="2023-09-13" version="1">MFARTFTAARALAQVRSSAAGPSARLFYTTEAAPATPQLLVRLKADVKDAMRAKDKERLAVVKGILSDLTYLEKSPQAPAQVNDSVIQVLIQKSIKRREESILNYKNAGRPEQAAQEQKEIEMLTVYLPSAMTEQEIEEEVRKVIKEQGATGPKDMGKVMKELGGLDPARAPKKTLALIKLVFSISSFSTISKNKGNKVSILKRLKPLRRSNVNLAEGTGPIPEIDPDQLTRTNEERAPKMQLGEPSLWEVRRLSPDLGVIPPLEHPIPFRKSHLYDSNVKIVDLTTGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZA5</accession>
    <name>A0A9P6SZA5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Carbohydrate kinase PfkB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_011426</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000918">
        <property type="protein sequence ID" value="KAG0012907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZA5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052562">
        <property type="entry name" value="Ketohexokinase-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42774:SF3">
        <property type="entry name" value="KETOHEXOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42774">
        <property type="entry name" value="PHOSPHOTRANSFERASE SYSTEM TRANSPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carbohydrate kinase PfkB" evidence="2">
        <location>
            <begin position="6"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0012907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="233" mass="26402" checksum="2E58F618F7C7820C" modified="2023-09-13" version="1">MPKIGVFLVGATYLDVIMHVNTFPHEDSKNRAQRVEQRRGGNAANSAEVLGQDPRTKVWYMSSMPSQVASKVLLKTLEENNVRTEACVFHPKQLTPPQAYIIAASDSGTRTIVSHSTLPDITVEDFIKKFDAACMRSSSDITELACPFRWIHFEGRGPDVYKMIDYVESVYIRQGWRHKLTISVEFEKGDRPGIKTLLQQADVCFFSKLYAETLGFDRPEDFLSSIGDYCKPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZF0</accession>
    <name>A0A9P6SZF0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">glutathione transferase</fullName>
            <ecNumber evidence="1">2.5.1.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">GSTS1_3</name>
        <name evidence="6" type="ORF">BGZ80_011252</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>RX + glutathione = an S-substituted glutathione + a halide anion + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16437"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16042"/>
            <dbReference type="ChEBI" id="CHEBI:17792"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:90779"/>
            <dbReference type="EC" id="2.5.1.18"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.18" evidence="1"/>
    <dbReference type="EMBL" id="JAAAID010000884">
        <property type="protein sequence ID" value="KAG0013159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZF0"/>
    <dbReference type="OrthoDB" id="414243at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050213">
        <property type="entry name" value="GST_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571:SF224">
        <property type="entry name" value="HEMATOPOIETIC PROSTAGLANDIN D SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14497">
        <property type="entry name" value="GST_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="4">
        <location>
            <begin position="27"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="5">
        <location>
            <begin position="111"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00047960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0013159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="255" mass="28940" checksum="E4C6EB88761ADDD8" modified="2023-09-13" version="1">MSARNRRPFIGSTSSDENARILADPNVSYRLLYWDVASVAASARDMLAYGKVKWANQLPVGNEWQEQKIPTPFGVMPVLNVISPDGKEVFLAESVVIDHYLAKRFGLLGDNEWEEFTIKGLYNNIHYLRERSFMNVTWTYEDKRKVALERFMNVTLPEFIANHQFHLKANGSNGHYVGNKHSLADIHLVNIMDHFSHLPTGATILAEFEKSEELMKVKKVVEQNPEIAAWRATEECKALAQGSIACYAQTAVPKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZG2</accession>
    <name>A0A9P6SZG2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Enoyl-CoA hydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ECHA5</name>
        <name evidence="3" type="ORF">BGZ80_011219</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000876">
        <property type="protein sequence ID" value="KAG0013223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZG2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.2460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018376">
        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006108">
        <property type="entry name" value="PRK08259.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43802">
        <property type="entry name" value="ENOYL-COA HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43802:SF1">
        <property type="entry name" value="IP11341P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00166">
        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0013223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="273" mass="29124" checksum="B27CB81414D57C24" modified="2023-09-13" version="1">MPKEDPSKLVLVEKRGTTTIVTINRPHKRNCVNGPAATALYQAFLDFDADPKAAVAILTGAGGNFCAGADLASIQNQDEANPMSAEWPDTLPGPIGPMGPTRMTLSKPVIAAISGFAVAGGLELALWCDIRIVDSTATLGVFCRLRGVPLIDGGTVRLPQVVGRGVAMDLMLTGRPVKAQEALKVQLATCYPPSYETVSETPALEQALALAASLANHPQTCMRNDRLSSHFASPIREAMLKEFEMGLNTLNSGEFIEAIRKFFDRKDSSSAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZW2</accession>
    <name>A0A9P6SZW2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_010261</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000697">
        <property type="protein sequence ID" value="KAG0014730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZW2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="209"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="63"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0014730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="243" mass="27319" checksum="71C9E942D6BFCF98" modified="2023-09-13" version="1">MGSTTVTTTQAFVFTFPTDSPLPQSQPTQSFNNVNQEADHISASSAQPNRHSCSTSGNLWENHQQQQQQQQQQQHQWKRKEFQEKATQRHPSPPPGRAGGPRLSLDTSFERLQNFTVIQHGDQSYLKLFSPALVESPVSFLSAKQILEDKKLWEGGPDEAFQRKLDMEKRETYQGQCLDHDSRHDTSPMLLFVVFMSCVAAVRAGTRCLIVAVATLAAVLTCFATLIANQSQYSTEFRVNKSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0N7</accession>
    <name>A0A9P6T0N7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sphingomyelin phosphodiesterase 4, neutral membrane (Neutral sphingomyelinase-3)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">SMPD4</name>
        <name evidence="6" type="ORF">BGZ80_009232</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000533">
        <property type="protein sequence ID" value="KAG0016439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0N7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050290">
        <property type="term" value="F:sphingomyelin phosphodiesterase D activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046475">
        <property type="term" value="P:glycerophospholipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006685">
        <property type="term" value="P:sphingomyelin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024129">
        <property type="entry name" value="Sphingomy_SMPD4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12988">
        <property type="entry name" value="SPHINGOMYELIN PHOSPHODIESTERASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12988:SF6">
        <property type="entry name" value="SPHINGOMYELIN PHOSPHODIESTERASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14724">
        <property type="entry name" value="mit_SMPDase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="177"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="192"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0016439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="818" mass="91854" checksum="8D85A182FCFCDA09" modified="2023-09-13" version="1">MSFEGLDRLLVGSVPTACANLTNHLNQCFDSDVHAKSFFEFLPRLCQILYGSKESRGWLHLPLSKAEEDPLYELIRPKGVLMRFLLSRYTDSGFIYEMVPDSLPKRTQSKLDPTQYLTLPPIYLSRVNLVKTIATVGTTQKTMAQVTKVNLNFNMLEYFLFYFAYALTLDDDDAQGRGMRRSDPKMAFKINGPPVGAAPSGGARSSDWTSGNAPKAPTSRVLVDGSFFNLFHQYLHYFIPAPERPKDAPNTNPDANSLQRPLSVFNDQAIENSADRQQTQLSISEFFIGTLVELWLGQNDKAVDNRTIRYVQPGADIAECISVLVSHLHAHDASAYVLGGDLVPSHIIDSTGKSVLNLAGMARRSAYQYIRPQLYTFLQLGLQFWPLDNTFPSLVNTWMIWITPWRYGRRDPSVAGDVVSEKWQVYGGQPFIFDNLLFYTALLELYMPRLSHAPQTSRSSTPPTPMTLKMELRSIQRVMKVFKADNLKEILKVAEQAIVWPENFSDSSYAVFESLSEGNPGGASSARPDATSVFLSSMVNALQRQIQQLEGHQYKYEALFLVEGPGRSKIRMILTKLGNAVDIRQERLAALEAKSKLAAEQTGLSALTSAISNIFAQPAPTTVSQDTTAYLSELKGLRDTMTMIGEVFDLYPSVVTSFEKQHQGTQDRGSTLTAEQLEALIPPLEEEESAGLLRPEKQRKYVPRGLVKRSVDEVKASGPRAEQLVLTYEIEFIVKLTRRAEDYLTPKTVPQRRVQELRTTTTTRAPEISNVKISGYDTHVEPVYHWERPGQASSTITRQRFTRPAEPRYTIDVQDIEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0S4</accession>
    <name>A0A9P6T0S4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Pheromone-regulated membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_009375</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the ThrE exporter (TC 2.A.79) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000555">
        <property type="protein sequence ID" value="KAG0016200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0S4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010619">
        <property type="entry name" value="ThrE-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051361">
        <property type="entry name" value="ThrE/Ser_Exporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024528">
        <property type="entry name" value="ThrE_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31082">
        <property type="entry name" value="PHEROMONE-REGULATED MEMBRANE PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31082:SF4">
        <property type="entry name" value="PHEROMONE-REGULATED MEMBRANE PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06738">
        <property type="entry name" value="ThrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12821">
        <property type="entry name" value="ThrE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="645"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="671"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="702"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="733"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="777"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="802"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="829"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="852"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="889"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="domain" description="Threonine/serine exporter-like N-terminal" evidence="8">
        <location>
            <begin position="515"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="domain" description="Threonine/Serine exporter ThrE" evidence="9">
        <location>
            <begin position="781"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="54"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="190"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="363"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="54"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="204"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="376"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="415"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00034125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF06738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0016200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="923" mass="99543" checksum="F9F1C96B99142A5D" modified="2023-09-13" version="1">MTESQIRHNMERNQLSLPLPSAIRSSSASVSFNIPTYPAIPRFTAPVPSRMSGNYTPTNTGYSTHHNPHGHANRLGTRSASNSPPGTPPSGLRNYYLNAAYQRSQSRFHTMGSVPGSSTSLHRPSLSVTLPLQSTHVHGPQAPQRSYSADNLKVHEPEITVTTPGGTNSTENHVISLERALSKLVEDRDREAIDEEDESDGFISVRISKPISASSSPPRTPGTPGTPGTPGTPGTPGTPGSPPHRKGIVKFPKVVTDCYDAEKAAEASTSAAAGTTVLTHDAEGSEVTLAGLGDAPEITERDLTNTKEKGKAKRRTPRLFHRYAAAPATEQNHTTTTVDLARQPSKAGVLSNLLKLHTNGRHHHDNYQAQQPKSPKPPKGKKQKRPGMYSRSAGNSFASIRGKSFLGTYPDLPPTDQSGINTTLSNFQPNPNRPSFQYESYSAQPSPFQSPYHSPGGSRRASLSGGENSSIFGYPYYGGDGLGGGSSGDSSMIALSNEEKIRITNAVADILERQDYILRLAKSMIKYGAPSHRLEETIDHSAKLLELNLQCIYMPNVMVISFTDFETHTSETHLLRVSAGLNMCKVALVHRVQKMISHSSTSVEEAIMKLDAINSEKDIFPRWLTVLGYGMASFCAAPMFFHGSWIDAGVSFLAGAAVSLLVWLSERLESYSHIGDVTMSVVVAFVAEALRNSNVCVSAVKLAGVVIILPGFTITSGILELSSRHMISGSVRLFYAVIFSLLLGYGLVIGTSLWNLVYPASQNEGAQTVCPGESLSALWNILFVPLFAISLNIWLKAHPKQWPTSIMLSIIGYSISYTTTVYAGAKTEVSSALSAFAIGLIGNVYQRWTQQLMYHAVVCAVFFLVPGSLGLKGAMSLFTDDMTGGVNFAIQMITTAIAISVGLFASTLVVYPFGKTRSAQMTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T181</accession>
    <name>A0A9P6T181_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008607</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000471">
        <property type="protein sequence ID" value="KAG0017122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T181"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0017122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="412" mass="46722" checksum="113DD8B602F19788" modified="2023-09-13" version="1" fragment="single">MTSPLKTVYIDFLGDLDYDRWTATLKYLAPEVDSSVEQMIVRMFRLLFLDHHMERVQTLSIPITHLEPYIKYTPSLKNLQRIRFYEDDLDGTQDQALNQSQDHQVNAPHDLDEQNTVGDADSNGENSAQEEVHILEDTAEQGDPNATEDSQLDISNAGDLEAMANNADQGTNTDETSETAQAQPEPVFDPTPRAIAFLKSHRKMFNPNQTSENFHRPFSLPGQSNQYPCRYGLLEVEPPYLWINPGWGSEPTRDSWYVGILQALESPAVVDLENWKLFVSQLNNTPLDGIKRIRSFCDDMPDIHWDQGKLLQRCRSLERFGAALRSSDAFGWALEEFKDRKIYEALLRDGVACAPSSLAQGTSHSSFFGPGLDPVPLRRVSLRNGNDDFIIPVLKDICWAFKKTLESIQVRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1M3</accession>
    <name>A0A9P6T1M3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">JmjC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_008436</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000457">
        <property type="protein sequence ID" value="KAG0017291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1M3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050910">
        <property type="entry name" value="JMJD6_ArgDemeth/LysHydrox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018866">
        <property type="entry name" value="Znf-4CXXC_R1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12480">
        <property type="entry name" value="ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12480:SF35">
        <property type="entry name" value="TRANSCRIPTION FACTOR JUMONJI, JMJC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02373">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10497">
        <property type="entry name" value="zf-4CXXC_R1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="JmjC" evidence="6">
        <location>
            <begin position="226"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="119"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="677"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="851"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="183"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="701"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="716"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="752"/>
            <end position="775"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0017291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="871" mass="99066" checksum="40930F3C388C8253" modified="2023-09-13" version="1">MIQGVFSHDTQIQTSVDLKDMDYDRIIALGYPFVPVKRVDVNQEGVDLEQEVESTCVEGGTPLVLEGWHKHPKWDHELFTFPYIDAKYGDEVIICRDLSISEDVPMSMKDYIRKVHPDCLQPIQPDTPNGSRSYDFPLTPASSSPPAAGEEDHANMSADEASTPLAKPDEDSIMEDVQGDATNKTDESADVSKEPHTTADRRRRSSRANAPKQQPLLYAKDVTCPKDWQDFLMDGVLPRFLGYMLENDLNTLNSKLAAENLMIYIGQAGTWTPAHIDQCGAIGHNVMAWADNDSYSLWFMIRAEDKAKAEDLWRSFGHPLEYEGYFASVDQLQKAAFPIYVVKQAIGDFVMVPSLGYHQVINMGKATIKVSWNRLTAHCLKAAVDVVLPRYREIARPEGYRIRTIIKSALEAWTDLLRSQSDSLPLPKERFCQSFKDILQLFRTIVEEEWVDLGVLGVENPKFNKPRRLQNAAPAVCDFCNSDLWNRQFHCLKCSENNDNYDVCIRCFALGRGCMHRATSMEFVEAFSMKSCQRLYSEAIQAWNMSKVLSGCQGYEEIVDEWTNGIVPSKNKDFSLTSVAYLRHESLTMTILSCHRCKSRRKNIINASCSDCPAEFCEKCLYKYYNILWKDVVAKGRWTCLKCTNACHCSTCDKKNNVEHQPNPIPVRDPVLSFTLPEEDQRNRGGVSDNMTRSFAISDESGGETEMEEENDSTKVRKPAPAHRGRIYQSKKRPMSLQELGSVKEVKRKRTSSSTKTSLSRDSSTMSESRSGSRTIRVTRAELENLMGVRDEMALRYAYSNGLWRTVQSIRTKEEDLAADYYRNLFQMDAYFMNKNKDIHNNFRRDILESHSSKKRAASQQMAENNGDVGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1N2</accession>
    <name>A0A9P6T1N2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006928</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000346">
        <property type="protein sequence ID" value="KAG0018632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1N2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0018632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="124" mass="14004" checksum="6A67E42371E64798" modified="2023-09-13" version="1">MDFVNCKIEKNSKQDSLEISLGALLSDIDMENVDTVFDVCHMLVINQIGMTSRTSALASFYRGLVPTWLTASIHKIYKTVAMRSNDQTPESDVGLKKYQEPKSSDKKKIVIKGKRNRVDHVIKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1Q9</accession>
    <name>A0A9P6T1Q9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_007139</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000360">
        <property type="protein sequence ID" value="KAG0018468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1Q9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY MULTIDRUG TRANSPORTER MFSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718:SF9">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY MULTIDRUG TRANSPORTER MFSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="37"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="98"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="180"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="205"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="230"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="270"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="311"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="1"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="337"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0018468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="394" mass="41696" checksum="2C621C59CD87940E" modified="2023-09-13" version="1">MSVGRALQGMGAGFTVPSALAILTTTYPAGPERNKALGIFGGTAAIGSVVGVLLGGILGSTIAQGKVEDRRLDIFGMASFTIGIVTIIYYLSESPAKGWTSAATLAPLIIGIVLLITFIVIELKIDYPIMPPHIWRSRRFLASCATALCLMAALNAHFYFSSLAFQDVLGYTSLKTSLAFITHGIGAIIAVGVLSMLIPHVRSKIFLVVGWVFMIASGVMWAQLKADSSYWSIPFPSLIVNLISMVCIWLTCQINSVADAADEDQGVVGAVYNVSLQIGAPIGIAISNIIANHKNGTFAVGSELLPGYIDAFYSFAVMGGVGLVVTLILYPNSDPVRPPTKAEETDVEVGTATAEDDERGTGDKEEIEEYSEIKAGSVNATVYSESSASLEKRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2S3</accession>
    <name>A0A9P6T2S3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003844</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000204">
        <property type="protein sequence ID" value="KAG0020655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2S3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0020655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="667" mass="76602" checksum="0B4445905B6EEF3A" modified="2023-09-13" version="1">MDGISEPPVPHGPPRPPGPHGLPEPSRPPPPFEPSTHELGTGEYMEKTCTRLDSNFEFESPPDFTKIGLESWTDCRSVQALDGWKVEHCTAPGSTWPGLIPNTHRGHLESFLPRAKRRQPGQQYAYTRAPETPFPSAASHEVKTAHPTQCNPSGYFKIQRINTPSTSYTLGSDNENPELRCRNNPDRPIALNETTKLYIEDFAGPDVFHVRLSGPEQYLADQQINLGNCTYAVPYVLSRPGRFWVSKIDHTYEDFQSINENFDKAFVPKFIGFNILPSVPPKPGQPATGSSNETIKAWNDYKKAASEVYSFNVCERCPEFLQPSSQTKCEHLPACSITSTEGSREYGVFTGLKSIEHFEDLDTQSYEWVASRPRCNHYPRLITFQSLETYRKNLENVKPIENPVYGSPPSWPDMQEFAKLHEETMNCMSRNRSIFLTGDSHIRQLFMDFVYRLQGAPSDFVGFEGWGTHTADIQAVKMRQDFDQWFQVIEKRIQYMLGDTSIPRTEGDEIDLMEKYDTVILDHGAWRACGFEIGPLWTSDQFAAFMPKFFWGLAEIRQKRRERYKKTGEGFSDFRVIWMGQVPWPDTRLTPDMRTNPRLKYWDFLINEEIDRINEHYKEQGGMIDRLNVFPKILPFRQLSPDSAHHVDKRLVDAIAQVLIHKLELCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2T6</accession>
    <name>A0A9P6T2T6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">peptidyl-tRNA hydrolase</fullName>
            <ecNumber evidence="1">3.1.1.29</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">PTRH1</name>
        <name evidence="7" type="ORF">BGZ80_003276</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the PTH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.29" evidence="1"/>
    <dbReference type="EMBL" id="JAAAID010000186">
        <property type="protein sequence ID" value="KAG0020966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2T6"/>
    <dbReference type="OrthoDB" id="1711136at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004045">
        <property type="term" value="F:peptidyl-tRNA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1470">
        <property type="entry name" value="Peptidyl-tRNA hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001328">
        <property type="entry name" value="Pept_tRNA_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018171">
        <property type="entry name" value="Pept_tRNA_hydro_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036416">
        <property type="entry name" value="Pept_tRNA_hydro_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00447">
        <property type="entry name" value="pth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17224">
        <property type="entry name" value="PEPTIDYL-TRNA HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17224:SF1">
        <property type="entry name" value="PEPTIDYL-TRNA HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01195">
        <property type="entry name" value="Pept_tRNA_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53178">
        <property type="entry name" value="Peptidyl-tRNA hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01196">
        <property type="entry name" value="PEPT_TRNA_HYDROL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0820">tRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="38"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="52"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="68"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0020966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="227" mass="25105" checksum="AE5689FA3B7DAE9E" modified="2023-09-13" version="1">MMVVDSIAKRFNAPWTKMGKWQADIATVTTTFSVKKKFPPQQKPCLHDVTPATPQATTGSKGNASSDPTTTTPTPTPVVRVRPPVEYETIDLKFTLLKSWQPMNLSGSSVFRAARDLNLKHSEILVIHDDMERDIGKISFKSQGSANGHNGIKSCIKSLSTQHFKRLRIGIGRPESNERSSAFIAKYVLGSFKPLEIEKLEELVYDKAGDEIIRTTVHPSTPALRSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2U9</accession>
    <name>A0A9P6T2U9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_003505</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000193">
        <property type="protein sequence ID" value="KAG0020835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2U9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030544">
        <property type="term" value="F:Hsp70 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071218">
        <property type="term" value="P:cellular response to misfolded protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.110:FF:000070">
        <property type="entry name" value="Endoplasmic reticulum protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051100">
        <property type="entry name" value="DnaJ_subfamily_B/C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015399">
        <property type="entry name" value="DUF1977_DnaJ-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43908">
        <property type="entry name" value="AT29763P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43908:SF3">
        <property type="entry name" value="AT29763P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09320">
        <property type="entry name" value="DUF1977"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="J" evidence="6">
        <location>
            <begin position="126"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="53"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="186"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="238"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="56"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="99"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="186"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="238"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0020835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="451" mass="50503" checksum="D9A98BBE2F28A86F" modified="2023-09-13" version="1">MEVNKDEAQRCLDIARRHLNSGNYASARKFGLKSISLFPTSDAEAFVKKVDKEEASATNTTSSSSNSTSTRAGTAYSASTGTSSARPSTTTPLRSRSAPVDHKPVEREYTSEQAASVRAIRSSGGDFYKVLGVKKDATDSEIKKAYRKLALLMHPDKNGAPGADEAFKIVSKAFTVLSDPQKRAIFDQHGPDEGRSSRVNYDRAHPTGHQFGRRGMQGDEISPEELFNMFFGGGGSFHSTSSRSRTQNYQQRQEYYRQQHQFQRQQRANATNNADLGNSLGSLIQLMPLILLILVTLSSGLFSSSGPGPSHTNSPANDFSLRPRDMYTTARHTTIRKVPYFVNDARFMNTYFPGQQFEFRSSDSRQINVKPDHVTLQGHKVGPLFKRMEENVEQEYLAMMRGRCKEERRKKEVARINAMGFWGADPKLWKEAERMTTPSCDVIKEKYGLSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T325</accession>
    <name>A0A9P6T325_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_002739</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000169">
        <property type="protein sequence ID" value="KAG0021270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T325"/>
    <dbReference type="OrthoDB" id="2438256at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="62"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0021270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="304" mass="33649" checksum="41BC29C782CA1040" modified="2023-09-13" version="1">MSSDVYTRVSEKMKQEHFTEEQIKIVGKAKEQLSTYTTGGSVIGGLSGLTLARAKNFKGLPAMAIITGCFFIGSQLGLVMGAMSSIKTIQSIPNFERVLNIVQEVRDEASRVGERRGPSQHDRAAAFPSAGIQRFPTQQNRSELMTDFAVEQQSQQFEGFRDGDGYHGGDDPTGQLRVDQSSAWSQAPQRAKELQNHSNSWNQIRQQNMPKSAWNDIRNGNRRSTTASDEIDEEDASGYSSNPDSKKASSVKPALTGWDRVRHGDADGFMNNGVAYDGPSDFARTREDLESRPSRQKNQYGDML</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3A5</accession>
    <name>A0A9P6T3A5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">GINS complex subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">SLD5</name>
        <name evidence="1" type="ORF">BGZ80_001239</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000128">
        <property type="protein sequence ID" value="KAG0022010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3A5"/>
    <dbReference type="OrthoDB" id="338231at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000811">
        <property type="term" value="C:GINS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11711">
        <property type="entry name" value="GINS_A_Sld5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036224">
        <property type="entry name" value="GINS_bundle-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008591">
        <property type="entry name" value="GINS_Sld5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038749">
        <property type="entry name" value="Sld5_GINS_A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21206:SF0">
        <property type="entry name" value="DNA REPLICATION COMPLEX GINS PROTEIN SLD5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21206">
        <property type="entry name" value="SLD5 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158573">
        <property type="entry name" value="GINS helical bundle-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0022010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="110" mass="12669" checksum="2047E551C68E1924" modified="2023-09-13" version="1">MSATDDFLNSNHSYRVASYDDLNFEDEDSVNHVRHLTQAWINERAAPDILQYEQSAVDGLLSKIEEQTATIDELDSSSDTLVIISILYQTELERVKFVLRSYLRTRISKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3J2</accession>
    <name>A0A9P6T3J2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cleavage stimulation factor 50 kDa subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">PHO81_1</name>
        <name evidence="12" type="ORF">BGZ80_000690</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000115">
        <property type="protein sequence ID" value="KAG0022244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005848">
        <property type="term" value="C:mRNA cleavage stimulating factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031124">
        <property type="term" value="P:mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14483">
        <property type="entry name" value="SPX_PHO81_NUC-2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057506">
        <property type="entry name" value="C2_GPCPD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044633">
        <property type="entry name" value="CstF1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030395">
        <property type="entry name" value="GP_PDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44133">
        <property type="entry name" value="CLEAVAGE STIMULATION FACTOR SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44133:SF2">
        <property type="entry name" value="CLEAVAGE STIMULATION FACTOR SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25329">
        <property type="entry name" value="C2_GDE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03009">
        <property type="entry name" value="GDPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03105">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51704">
        <property type="entry name" value="GP_PDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 7" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="SPX" evidence="10">
        <location>
            <begin position="1"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="7">
        <location>
            <begin position="333"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="7">
        <location>
            <begin position="366"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="7">
        <location>
            <begin position="399"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="7">
        <location>
            <begin position="465"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="7">
        <location>
            <begin position="502"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="7">
        <location>
            <begin position="532"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="domain" description="GP-PDE" evidence="11">
        <location>
            <begin position="819"/>
            <end position="1187"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="1316"/>
            <end position="1357"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="1366"/>
            <end position="1406"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="1472"/>
            <end position="1513"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="1523"/>
            <end position="1557"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="1603"/>
            <end position="1634"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="203"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1026"/>
            <end position="1056"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1184"/>
            <end position="1210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1453"/>
            <end position="1476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="205"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1030"/>
            <end position="1043"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1186"/>
            <end position="1210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1456"/>
            <end position="1465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0022244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1647" mass="180135" checksum="B69D556E4F1CDC20" modified="2023-09-13" version="1">MKFGKQIQFQQITEWQNHYMSYKGLKKIINSLIQDKAQTSVTIAASPPPGSVPVIPEDDYSKFLQSQKAAFFFKLERELEKVNSFYLQKESELKVRLRSLIDKEKVILSRQGRPGTSSSINSLKEAYRQFEQDLNKLQKFVETNGTGFRKILKKWDKRSKSSTKELYLSRQVELQPCFNQDAMVELADNAAYHLLQLENIQQGNSRSSSAPSSPITTKSSQSVSTSVLSSPMQQQMDELETDLFNALTSNQSSLVQEILERRLATPSALQNNSISTETSTNTNNNIQIGPENAREVISRVFWRCCSETSTSDSVIQQLVKTGLINFKFVDDISDRTCLHEAAMVGRLSLLKLAVEHGVSPECADVYGRRPLHYVSMYGHADCATYLLSMNASMKATDHDGFRPLIYSIMNGHTKCVEIFLANDAEIEASQEGDPIPLSLACHYGHEDIAMMLIGRGANVIACNADGLEPLHITCREGHTKLAKTLTTRGARLDQEDKYMCWTPLFYAASEGHADCVKILLEAGCNVNVIDELGKTPIYYAASEGHADCVELLVEAGGKVEGKSAPAEDTAMDAPGPMSTTGMMTTTTTPAAGSTLGASGSLSSPNMDDLDMDCIPSLSLPPPIIPFRIYGHNYLDKKYQINLTLGHPNYPNHSTEDKTARQAPVHLYGTAQTSSLKLIISSRPDNGMIPHNVILPLVDDREVFGFQVDSLEHFTVEFDIFPTFGSKAIGRAVALPSVFSSLETSMGKGVLPLFDAHLKVVGELAFEYSVIRPFQGVRLEVGGRVETYWKSTNSIDSSISTASTPQVGTPSVMPVSMSTSGSALPHSSSQSLLVGNIIPSFITASSLSGEYIQLSIQMTRDFVPVVFASWHLPVEGFDLAVSDVTFSQFKAFGELIHQKASDDLEASTNRLASSWRSGEWRRKIYERWMSLEQVLKILPKHIGVNLELKYPTLSERTHYRLTNYVEVNKFVDTILQTVYDSSSATHHRSFMFSSFNPVICSALNWKQPNYAVFFSTYCGYNKSRSRVVPSTEDHSQGLKRKEPIDPESLPSPKHGSAAQLPSIAAVSSSASPSLSPSSKSGSPLLARSATASSAAISDMEFYEDDKRCMSIKEAVKFARSNNLLGVICEATPLIQVPSLITHIKESGLILSSFGPGNKDPAQVQIQKSNGVDAFMVMENSNPESRLASSYTSLPTSSSPATSTGLGSSKVSSKSSATAVAGSIQLAEYGYAQLASLVAEQTHTSVSIKPSSQLSEMLYIAKEESVEIEPTDLSKADAFVDEEYDDDVEAGSTMTRLNLDVDPKSTPLRPPTLNVVNTVTHKEAVTCTAFSRDGRYAASGSADCSLKIMDVNKMKQAIDDVHPVIRTLYDHDTPVTATEFHPNGLVLAASSDTTVKLYDISKPSVKRSFRYLQDSHPICSISFHPSGDFLLVGSEAETVRIFDVKTLQCFTPRPFSGPPSHSSATSSVDQVQQQGPHRGGINHIEYAPTGSVFITASQDGSIKVWDAMSGKVVRTIENAHSGKGVTTATISKNGKYILSGGWDSVNKLWDLGSGKMIHGFQGAVQKNIKQSTVFSYNEDFVFSSDESNNSFVCWDSRTGTLLKRYVSQEAMIRSISASPSENAIVSGGDDNRVRFWCMPGSTATMSEPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3K9</accession>
    <name>A0A9P6T3K9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Alpha/beta hydrolase fold-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_002811</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000171">
        <property type="protein sequence ID" value="KAG0021243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3K9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF26">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="2">
        <location>
            <begin position="180"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0021243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="500" mass="55971" checksum="17F058BB096F309E" modified="2023-09-13" version="1">MTTVSTVSHTALITQSISVKKRSSFAFPIRNLRRYLAFISQELAIGASLIIRHPFTPPPVPTWPLHLALFVAIIRATADIQEHIVEDISDIRRLIDAFFYYLPKLPQMQIVPFKVPIPAKGRAFPGVLAQLEQSETGHRTLPAQWIADTRVWDRIMKMPIASTAAESKDPFAAREGEKVIFYTHGGGYFICSTDTHREMLWRISRATGRRIFAVDYRLAPEHPYPAAVQDASHAFSHLTDPKGCGFAPENVTSSGDSAGGGLTLALLMYQRDHGLPMASKAVLLSPWLDLTMSCDSWVTNSVDYLPSPPKFEHKFNPISFYCSGRENIKTLARHPYISPLWGDLEGLPPLLIQCGEAERLRDECILFTYKAGGCFGPSNTLPFEPETLSRDQNSHVELDMYPGMVHVFQAIPFLPEAGMALERIRDFMHRKEADNEAEVTEAAVDMTKTERIEDDSLFTADEQSAIAQLMEELVENAAIQSSDDSSLYLELNEEELICRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3T4</accession>
    <name>A0A9P6T3T4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Sugar phosphate phosphatase</fullName>
            <ecNumber evidence="8">3.1.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_010938</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">Metal-dependent phosphatase that shows phosphatase activity against several substrates, including fructose-1-phosphate and fructose-6-phosphate. Its preference for fructose-1-phosphate, a strong glycating agent that causes DNA damage rather than a canonical yeast metabolite, suggests a damage-control function in hexose phosphate metabolism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>beta-D-fructose 1-phosphate + H2O = D-fructose + phosphate</text>
            <dbReference type="Rhea" id="RHEA:35603"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:37721"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:138881"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 8">
            <text>beta-D-fructose 6-phosphate = dihydroxyacetone + D-glyceraldehyde 3-phosphate</text>
            <dbReference type="Rhea" id="RHEA:28002"/>
            <dbReference type="ChEBI" id="CHEBI:16016"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="8">
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
        </cofactor>
    </comment>
    <comment type="domain">
        <text evidence="8">Subfamily III proteins have a conserved RTxK motif about 40-50 residues from the C-terminus; the threonine may be replaced by serine or cysteine.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.-" evidence="8"/>
    <dbReference type="EMBL" id="JAAAID010000082">
        <property type="protein sequence ID" value="KAG0022871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3T4"/>
    <dbReference type="OrthoDB" id="541375at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004427">
        <property type="term" value="F:inorganic diphosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030643">
        <property type="term" value="P:intracellular phosphate ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10880:FF:000005">
        <property type="entry name" value="DUF89-domain-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.930.60:FF:000002">
        <property type="entry name" value="Protein-glutamate O-methyltransferase C1393.13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10880">
        <property type="entry name" value="Uncharacterised protein PF01937, DUF89, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036075">
        <property type="entry name" value="ARMT-1-like_metal-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039763">
        <property type="entry name" value="ARMT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002791">
        <property type="entry name" value="ARMT1-like_metal-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12260">
        <property type="entry name" value="DAMAGE-CONTROL PHOSPHATASE ARMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12260:SF6">
        <property type="entry name" value="DAMAGE-CONTROL PHOSPHATASE ARMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01937">
        <property type="entry name" value="ARMT1-like_dom"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111321">
        <property type="entry name" value="AF1104-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 8" id="KW-0464">Manganese</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Damage-control phosphatase ARMT1-like metal-binding" evidence="10">
        <location>
            <begin position="28"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="Damage-control phosphatase ARMT1-like metal-binding" evidence="10">
        <location>
            <begin position="263"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="233"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="235"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="262"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00054243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU367030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0022871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="519" mass="59117" checksum="5BC9962638CF5817" modified="2023-09-13" version="1">MSTVTIDPLHPPRKALSGSDTKSFGYATIQSRLPVIVSKIVDDVYRTYHNLPDSDPLKEQKDKEAKQIIEAIGGLRYELQRDKPFRPLQDNLPDVGEWNQALADYYPSSSWFKASWLFAECYLYRRIKEAFALTQYWCDYDPFFSQKQTVFKSSQKAVVAIAVRLMSPTNKGSERDGSQSLSSLDILVSQAVGTEQAFFELVQICLWGNATDLSLLDNPDLAKVEELQRRVMMGSSPSPSSVASSNNSSNINLDKQNQEQVQNRREDDHATSELEKHAEKILQNDSDLLWEKVKTMRNGRVDIILDNAGFELYVDLVFADYMIRAGFASKVVFHAKRIPWFVSDVMPFDFQWAIDQLHKAGETAGSSPFFDPIDPIEQQALKDLGHKWQSYVDQGVWTVTSHDFWTSCYPFHHLPFLPSAQNLFQDMKQSDLWIFKGDLNYRKLVYDCQWPTTTPFKETIGSLSSHEEVPSLVTFRTCKADVVVGLKAGVEEKMNNVAKDWMVSGEYAVISFSNRDSKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T400</accession>
    <name>A0A9P6T400_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Proteasome subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">PSMB1</name>
        <name evidence="6" type="ORF">BGZ80_009989</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the proteasome complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the peptidase T1B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000065">
        <property type="protein sequence ID" value="KAG0023254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T400"/>
    <dbReference type="OrthoDB" id="268479at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019774">
        <property type="term" value="C:proteasome core complex, beta-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03757">
        <property type="entry name" value="proteasome_beta_type_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000027">
        <property type="entry name" value="Proteasome subunit beta type-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016050">
        <property type="entry name" value="Proteasome_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="METALLOPROTEASE TLDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194:SF2">
        <property type="entry name" value="PROTEASOME SUBUNIT BETA TYPE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00854">
        <property type="entry name" value="PROTEASOME_BETA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 5 6" id="KW-0647">Proteasome</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00026071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0023254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="231" mass="26034" checksum="633C0F9AA9154161" modified="2023-09-13" version="1">MNSIYQAAIDHPVSVPIEHRFDPYVDNGGTLLSIAGEDFCVVAADTRQSEGYSINSRYVPKSVKLSDKTVISMGGCYADCLTLTKRIQQSMEWYHHAHGKTMSTAAVAQMLSIMLYQKRFFPFYSWCILGGLDEEGKGAVYTYDPVGSYERESCRCAGSASSLIQPFLDNQIMFKNQETLKKNLPLDHVLRITKDSFTSATERDIYTGDYLEIFVITKNGVEIQKMDLKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T466</accession>
    <name>A0A9P6T466_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome p450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_008581</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000047">
        <property type="protein sequence ID" value="KAG0023667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T466"/>
    <dbReference type="OrthoDB" id="1844152at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11041">
        <property type="entry name" value="CYP503A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="3 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="488"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0023667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="542" mass="60961" checksum="0423BB9D7FB0532E" modified="2023-09-13" version="1">MIGLISNSPTVGVPMEAIKVALPIGVGLASAAFLAMKAAANSGYTTDKSIPMASVRQGDSTHDNEYYDDQDAFLRRCEEEYGPVFNIHLLNKPLTVVSGPQIREVFMNDDFSAGDAIDEFTGMRAFFDSVRKSNKDVDNRVIHEVVRDTISPNLSLFTPRIVEQLEKNLEKELGTCPKEEGGKFVAKPILVLQEMVANAMANVFVGPEIAKSREVINTFITATADFGRVLGNGERRMSFWRAFTRRANYKVFNPLQIHVRILVEASTPVILERRRLEAEANEKGEKWERPDDILQKLLDNFDKYGFVDLEDVCGHLMILILASVHTTTDTSTNLLYYMATYPEYLDKLYEEQQQVLDAVQAEREKERQELVKKGEPIGEDLDPAHDRDLSAATIKRMVHMDSFVREVFRFRTERLTLIHRARKDIRLSSGITISKGSSVIINMRSAHQSPEQGEDVTEFRPWRFVGKPKAATKAGSDFLPFGMGKHACPGRFLAIQELKTIGVLMISKYSKIEIEDPSKAMKILRSRIGTPNCTGLTFTSRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T4N6</accession>
    <name>A0A9P6T4N6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Up-regulated during septation protein 1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_002071</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000015">
        <property type="protein sequence ID" value="KAG0024511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T4N6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029191">
        <property type="entry name" value="Uds1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15456">
        <property type="entry name" value="Uds1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Up-regulated during septation protein 1" evidence="2">
        <location>
            <begin position="840"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="262"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="406"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="536"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="644"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="962"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1139"/>
            <end position="1185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1203"/>
            <end position="1270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="123"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="271"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="285"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="310"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="324"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="357"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="406"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="429"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="467"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="589"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="609"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="648"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="667"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="718"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="778"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="967"/>
            <end position="979"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="984"/>
            <end position="1000"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1143"/>
            <end position="1152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1165"/>
            <end position="1185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1203"/>
            <end position="1212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1260"/>
            <end position="1270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF15456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0024511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1270" mass="140453" checksum="8C08C4F25947B9A1" modified="2023-09-13" version="1">MVSKELPTPPASTSTLFDYQGQSTSTTLSREENNNGMHQLPHIVTDLAHKGPALAELIPYSPPASKKGIPIERPYSYYKVAPKVPQSVTVIDSPFGPPDPPASLPATAEGQYNFFNGNSTSTYYTHPSTSNPFVPPAQYQPSLPHQQPQTLQYATHGGRSGKERPDPEDSIPGPYFSAESIATRGSRERSNHDKQGQRDRSYSNESGSHPSRERQQPNHRGGQDQEANHDDTNDSSVPVRKGSGNNLLRIARKASDTALKGIGLSRKASGKKASQSSGAPAPNNAYEQNSQSWSAVGNRPQPELHRGQHSEFSAQTDSGNQRTRNYDLSRTYDTDLGRNRSLPDIKPPPNADHRTPSRGSSLNNSRTNPGASHSRQKSQHHLQDSASNVVQDAYGGIADDWRQRQQVEKEARERLDLRDSSPTERPGHTSINSVSTLNLPPSTVVPTATSINRSTSRILLPDRDRSANQLGSSQSSNPGKQDTDHEPTQESTSLAKATVQPGGILAQLQAATEAGQVIDPAMGIWSQKDGRYIQRSNTAPYPHRENKTILEEDESGSPTSGGPRSPGPLEYSKSEGYAAASRNNRQQKRPQQQQTQVQQHAQIHDQEQSTSAQNQYPNYNDPHREPYQQTNYQAHHLPHQAFHEQPYQHQQQQQQHHQQQQQQQQQNQTISRSRAMSNENMDTNKDLPPTPGRTLQDATSDMADRQAAHGRSRHQQTEPRSQTQRQPRSRSESQSESARRHHQQQSSGWQAEMAESVLALSRSMSPPRNRSASRERTNGQLTRRGSNGQHSGGQRERDQYGIDMFPLPVIPSPDETLKKNDNVGILPQDVLRTLDLQTVQKVVTQAVIASRVYKALSLVEVENLKKEQDDLQRYVETLKVSLTIETRMRDASHSLIRLHENNTNIEAVKASTGQLHATTRKVDQIVQKIQQSMDRLLVIQRLLLEHEGAVLNAGMRRLDGELPGMVTNGTAKPTEVSSAQGQRPPSPPQPQPQPGVPTPPLQQQHAARLTALENYMKELNEEINKKDERISQLESQLRLIKTWADDFAGSLRSRIGVDNSSVCDEHASAKHDGAESPAKLQKQLAHLQSRIEDGFRALETNAHELNTKAREAELAKEKALEFAATTLANTGAIGIPAADLAQSSSSSSVGESESPRSRLRGPFSRSKSSLNESRYPQTNHSNNSDLNVVLNESLIELDLQLSSSSSANSSAAPTLDRMNGKGRQHSTESPTQRQEQARRASRSKHQPEGKDDLVIGDANELERSAKLKMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MCD7</accession>
    <name>A0A9P6MCD7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_009032</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010005119">
        <property type="protein sequence ID" value="KAF9991579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MCD7"/>
    <dbReference type="OrthoDB" id="2448111at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="55"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="120"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9991579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="145" mass="15794" checksum="0F6160CD520F3A8D" modified="2023-09-13" version="1" fragment="single">SGSSAPTATSPTQANASNQLSGEVCEPEKAEGVTGVVSSQSQIHQAVQIPQSTSQQNQYQLPALPQQQQQQQGHAYIPQTTYVPQTTYVPQTTYVPQTAYVPQTTYVPQTNYVPQSTYKPQTKSTSLPSQQQQQSQMQHSKSQPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MCG2</accession>
    <name>A0A9P6MCG2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">MULE transposase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_008772</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004883">
        <property type="protein sequence ID" value="KAF9991982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MCG2"/>
    <dbReference type="OrthoDB" id="2444301at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9991982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="118" mass="13297" checksum="F2A1124495609AEB" modified="2023-09-13" version="1" fragment="single">VYRARTSGSRKSINPTNSVKLWMEQIEKEGGKSIFVDNVTGITNQYFFAWSTEFQLEVMSRHSGIVCMDSTHKTVRSLLPDPDDDKVFPSAYLFTLLVRDRAANIGVPIAFMVCNSES</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MCZ6</accession>
    <name>A0A9P6MCZ6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Suppressor of the cold-sensitive snRNP biogenesis mutant brr1-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">SUB2</name>
        <name evidence="8" type="ORF">BGZ80_008277</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004438">
        <property type="protein sequence ID" value="KAF9993097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MCZ6"/>
    <dbReference type="OrthoDB" id="10265785at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="7">
        <location>
            <begin position="49"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="6">
        <location>
            <begin position="80"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="5">
        <location>
            <begin position="49"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9993097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="211" mass="23507" checksum="A79FD5EF79F388DC" modified="2023-09-13" version="1" fragment="single">MADHHDDLVDYDEDDEVIQSINAVPAATEPEAAEEAKDKKGSYVGVHSTGFRDFLLKPELLRAIVDCGFEHPSEVQQECIPQSILGMDILCQAKSGMGKTAVFVLATLQQVEAVPGEVAVVVLCHTRELAFQIKNEYARFSKYLPEVRSEVFYGGTPLKRDQDILRNKELCPHILVGTPGRVLALIKDKTLNLKSVKHFVLDECDKMLDQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MEF8</accession>
    <name>A0A9P6MEF8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_007634</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003945">
        <property type="protein sequence ID" value="KAF9994991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MEF8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9994991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="118" mass="13704" checksum="1F427EB98F487645" modified="2023-09-13" version="1" fragment="single">MESLPLLEILHIEIQNAAFSDIHLMGTIFRQPWICLPLKEFHLDHIKITLPQQDEIFDSPPSSFMIPFSSYVGFGWYVPQETLINDHHAAKQRNEFTKRLFEHVQGMPQLKSVCLNTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MEJ5</accession>
    <name>A0A9P6MEJ5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">PT3</name>
        <name evidence="1" type="ORF">BGZ80_007416</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003796">
        <property type="protein sequence ID" value="KAF9995780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MEJ5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9995780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="107" mass="11611" checksum="F0121DAE53F9975F" modified="2023-09-13" version="1" fragment="single">MLGSSFTEKTEDAGEVHYETGSITYADKPAAGLEALEDNHRWDWFTIRTLITSGTGFFTDAYDVFVINLISPMLGILYYPQYGGHIPAGTEGVLKGMSSVGTLVGQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MEL8</accession>
    <name>A0A9P6MEL8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Sodium:solute symporter family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_007495</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003857">
        <property type="protein sequence ID" value="KAF9995477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MEL8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015606">
        <property type="term" value="F:spermidine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="entry name" value="Sodium/glucose cotransporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050277">
        <property type="entry name" value="Sodium:Solute_Symporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48086:SF10">
        <property type="entry name" value="AGR155CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48086">
        <property type="entry name" value="SODIUM/PROLINE SYMPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="73"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="120"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="160"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="226"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="266"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="308"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9995477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="332" mass="35640" checksum="F10243823AC725D1" modified="2023-09-13" version="1" fragment="single">MSLESVTYGLSVTTIVLFGLSALFLARRRQRVKQDDTEFFLTARHSVPLRTIAWSFYAQGVGAWVIFSMPAYVVSAGMVGLVAYSISCGLPIVIVAYVGAILHRKYPGVLSLGDFVQWRFGTIPTIIVTVVMLFNMFIALCAEYTSIGNLMELVIGAPRLPIVICVAVVTSVYTAAGGLYVSILTDVGQGVFGILLLVIMYIYVAVTFRPASLPTPLSPELGANYWGWAAVGAMPISMTCATFFSEAPWQRIWASADERALKKGSIIGALGLIVVCFLYGFGGFLSLWADFPQTSTDGSTAFFDLLNAGNATAPGWIVVLAALATVTMNEGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MES2</accession>
    <name>A0A9P6MES2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidase A1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007660</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003964">
        <property type="protein sequence ID" value="KAF9994899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MES2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase A1" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9994899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="66" mass="7047" checksum="A1B1773B4A34C213" modified="2023-09-13" version="1" fragment="single">LGGKTFNVPLADLAYEDLEDGSGNCFSGIQGGQDDLWILGDVFIKNNYCVFSQTSSPSIGIAPLNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MFI1</accession>
    <name>A0A9P6MFI1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tetrahydrofolate synthase</fullName>
            <ecNumber evidence="3">6.3.2.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Folylpoly-gamma-glutamate synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Tetrahydrofolylpolyglutamate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">MET7_2</name>
        <name evidence="13" type="ORF">BGZ80_007093</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>(6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n) + L-glutamate + ATP = (6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n+1) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10580"/>
            <dbReference type="Rhea" id="RHEA-COMP:14738"/>
            <dbReference type="Rhea" id="RHEA-COMP:14740"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:141005"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; tetrahydrofolylpolyglutamate biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the folylpolyglutamate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.17" evidence="3"/>
    <dbReference type="EMBL" id="JAAAID010003574">
        <property type="protein sequence ID" value="KAF9997056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MFI1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004326">
        <property type="term" value="F:tetrahydrofolylpolyglutamate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="entry name" value="Mur ligase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="entry name" value="Mur-like, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001645">
        <property type="entry name" value="Folylpolyglutamate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018109">
        <property type="entry name" value="Folylpolyglutamate_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01499">
        <property type="entry name" value="folC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11136:SF5">
        <property type="entry name" value="FOLYLPOLYGLUTAMATE SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11136">
        <property type="entry name" value="FOLYLPOLYGLUTAMATE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="MurD-like peptide ligases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="MurD-like peptide ligases, peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01012">
        <property type="entry name" value="FOLYLPOLYGLU_SYNT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAF9997056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="360" mass="38633" checksum="0681BC41B65358F9" modified="2023-09-13" version="1" fragment="single">DKSKPGYFRFLTVLAFHVFKQEKVDVAILEVGVGGAYDSTNIINKPIVCAITALGIDHVSVLGSTLGEIAWNKGGIFKSGVPALSSQQPEEGLTVLESRAKELGTASFQVIPPFSDEEMKGQIVGLAGKHQVANAALASAICRIWIEKVLNVNIDAPEGSIPKEFSKGLSSARWPGRGQIIVREDKPKITWFFDGAHTAESLRVCATWFKDASQSRIQGTVKKILVFNCTGPRDGDSLLGPLAKIQSIVRFDEAVFTPAITFASNTYKGDLVNNNTAIDTELKTQNTLAACWTKQVGLASGSDSEKVKTKVLPSIEHTVNWIDDYVKSEAGHGVDNVQVLVTGSLHLVGGVQSVLGCEIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MGK2</accession>
    <name>A0A9P6MGK2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006599</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003269">
        <property type="protein sequence ID" value="KAF9999256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MGK2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="59"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9999256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="105" mass="11261" checksum="F207767F4A472599" modified="2023-09-13" version="1">MRAAANEFTAQVQALRVTAELQRLNLGLKNQKKVTPSKNGKGKTPPSRRTSELSKFKGPKGPAKGKNGKKSGPPNKTSNKNKTPPMQKKGRGKGPVKGARSQSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MHB2</accession>
    <name>A0A9P6MHB2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_006370</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003141">
        <property type="protein sequence ID" value="KAG0000423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MHB2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0000423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="72" mass="7331" checksum="D4294B098B34628F" modified="2023-09-13" version="1" fragment="single">FNTLQLSSSQISTTAASAVPASAIPASAVTTGKTGADQKDKAIRRASGLNPNLTESINSGISTYTKYCIIIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MHM3</accession>
    <name>A0A9P6MHM3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ATP citrate synthase</fullName>
            <ecNumber evidence="4">2.3.3.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">ATP-citrate (pro-S-)-lyase 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="19">Citrate cleavage enzyme subunit 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="24" type="primary">ACL1_1</name>
        <name evidence="24" type="ORF">BGZ80_006190</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="24" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="24">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Catalyzes the formation of cytosolic acetyl-CoA, which is mainly used for the biosynthesis of fatty acids and sterols.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>oxaloacetate + acetyl-CoA + ADP + phosphate = citrate + ATP + CoA</text>
            <dbReference type="Rhea" id="RHEA:21160"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16947"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.3.3.8"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="17">Composed of two subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="16">Belongs to the succinate/malate CoA ligase alpha subunit family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="24">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.8" evidence="4"/>
    <dbReference type="EMBL" id="JAAAID010003041">
        <property type="protein sequence ID" value="KAG0001406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MHM3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003878">
        <property type="term" value="F:ATP citrate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006085">
        <property type="term" value="P:acetyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06100">
        <property type="entry name" value="CCL_ACL-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.580.10:FF:000009">
        <property type="entry name" value="ATP-citrate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.261:FF:000008">
        <property type="entry name" value="ATP-citrate synthase alpha chain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.261:FF:000003">
        <property type="entry name" value="ATP-citrate synthase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.230.10:FF:000005">
        <property type="entry name" value="ATP-citrate synthase subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000024">
        <property type="entry name" value="Probable ATP-citrate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.580.10">
        <property type="entry name" value="Citrate Synthase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.230.10">
        <property type="entry name" value="Cytochrome P450-Terp, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="entry name" value="Succinyl-CoA synthetase domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017440">
        <property type="entry name" value="Cit_synth/succinyl-CoA_lig_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032263">
        <property type="entry name" value="Citrate-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016142">
        <property type="entry name" value="Citrate_synth-like_lrg_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016143">
        <property type="entry name" value="Citrate_synth-like_sm_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002020">
        <property type="entry name" value="Citrate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036969">
        <property type="entry name" value="Citrate_synthase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033847">
        <property type="entry name" value="Citrt_syn/SCS-alpha_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003781">
        <property type="entry name" value="CoA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017866">
        <property type="entry name" value="Succ-CoA_synthase_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005811">
        <property type="entry name" value="SUCC_ACL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23118">
        <property type="entry name" value="ATP-CITRATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23118:SF42">
        <property type="entry name" value="ATP-CITRATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16114">
        <property type="entry name" value="Citrate_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00285">
        <property type="entry name" value="Citrate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02629">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00549">
        <property type="entry name" value="Ligase_CoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01798">
        <property type="entry name" value="SCOASYNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48256">
        <property type="entry name" value="Citrate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52210">
        <property type="entry name" value="Succinyl-CoA synthetase domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01216">
        <property type="entry name" value="SUCCINYL_COA_LIG_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00399">
        <property type="entry name" value="SUCCINYL_COA_LIG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01217">
        <property type="entry name" value="SUCCINYL_COA_LIG_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="13" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ATP-citrate synthase citrate-binding" evidence="23">
        <location>
            <begin position="1"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="CoA-binding" evidence="22">
        <location>
            <begin position="199"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-citrate synthase/succinyl-CoA ligase C-terminal" evidence="21">
        <location>
            <begin position="364"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="134"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="134"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="24">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00054002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00060724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00062455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00076189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00083544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF00549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF02629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="Pfam" id="PF16114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="KAG0001406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="818" mass="89687" checksum="53862A08DD694192" modified="2023-09-13" version="1" fragment="single">AHELANYGEYSGAPTETQTYEYAKTILDLMTRSPTPHPEGKVLIIGGGIANFTNVASTFKGIVRALTEFKQPLISHKVRIFVRRGGPNYQEGLRSMRQLGESLGVEIQVFGPETHITEIVPLALTGKSSDNLATTNDVNGNSSGNLLQDQLLGSNTNAGTPLPTNPPSRSVTPPQERMTYFTDAEKVTEHDNNVPFTAHTRSFIYGMQPRAVQGMLDFDFICKREVPSVAAMIYPFGGAHVQKFYWGTKETLLPVYTTLEEATAKFPEVDTVVNFASCRSVYQSTLDILRYSSQIKTIAIIAEGVPERRARQILWEARQKDVLVIGPATVGGIKPGCFKIGNTGGMMDNIVSSKLYRPGSVAYVSKSGGMSNELNNIISRTTDGVYEGVAIGGDRYPGSTFIDHLLRYEQDPNCKMLVLLGEVGGVEEYRVCEAVKSGKIRKPVIAWCIGTCAKMFATEVQFGHAGALAQSDLETADAKNKALRAAGVVVPETFEKLPLVLNQTFQNLVKQGTIQLKPEPETPKIPIDYSWAQELGLVRKPASFVSTICDDRGQELLYAGMRISDVFKEDIGIGGVLSLLWFKRRLPDYACKFIEMVLMLTADHGPAVSGAHNTIVTARAGKDLVSSLCAGLLTIGDRFGGALDGAAEQFSSAYDKSLTPREFVSLMRKQNKLILGIGHKIKSRTNPDLRVEIIKSYAKNHFPSTPVLDYALQVENITTSKKDNLILNVDGAIGILFVDLLRHSGAFTREEAEEYIKIGTLNGLFVLGRSIGFIGHYLDQKRLKQGLYRHPWDDISYLTPGNELGRTVASLDSINKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MI40</accession>
    <name>A0A9P6MI40_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Multidrug resistance-associated protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ABCC6</name>
        <name evidence="10" type="ORF">BGZ80_006176</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003033">
        <property type="protein sequence ID" value="KAG0001483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MI40"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18579">
        <property type="entry name" value="ABC_6TM_ABCC_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044746">
        <property type="entry name" value="ABCC_6TM_D1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056227">
        <property type="entry name" value="TMD0_ABC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF399">
        <property type="entry name" value="ABC TRANSPORTER ATNG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24357">
        <property type="entry name" value="TMD0_ABC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="24"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="240"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="271"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="346"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="373"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="451"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="236"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="682"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0001483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="682" mass="75225" checksum="2BD8A138B404E797" modified="2023-09-13" version="1" fragment="single">MALALQIALLAVLAKRDYPSSSILSSVLYGVSILAALILHYFEHFNMPNSSSMLLVYWLFTALISIFPTRTRIEQSPNSLADSLPLLKLLFAVVSSLVFGLENITKPDHRSLARPDVDKLVQVNPSPELHANLFSRLTFIWALPLLNKGKKKTLKMDDIWSLHPKMLSYPLFLSTQARIDADEAIARQKTQDLAENKTRATSGETADTFQPQKIRLFSILVHTVGWAYLTAVIPCLLYTIAMYSSPVLLAGLIAFMTSYTEGSNVTEQPVWKGYGLVLGVLTTSVLCAVFNAQYKDICFQCSICACGVFNSLIYRKALRLSSTNKQEGMGSIVNHMSIDVDNVLQLFGIFHMLWSSIIGVVIALVLLYRQVQYAMLAGLGVTFGIAIVGGFISSMTGKVYGQMSAKNDHRMNLVSELVNHIKPIKLYAWERYFIRQISEARLKQLNSLRSFFIVLTSQIAIYNMGTPLTSFALLTVYSYTAPLSAALSLEKIFTCLILLSMLDTPLSYLGNSISTIVSGHVSYVRLRAFLDSEEINLDNVERHPNAGLSENAYEVNNGTFGWYSPEAIKKLEEKREKEANDTMKNKTDVPEAAQKDEMIAVDEKSGVAGSDAISDSTVASIKENNDESAGDTLGPFLRNVSFAIKRGSLTAIIGRVGEGKSSLVAALLGEMYKYSGSVRAYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MJ74</accession>
    <name>A0A9P6MJ74_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">Acetolactate synthase</fullName>
            <ecNumber evidence="4 11">2.2.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">ILV2_1</name>
        <name evidence="16" type="ORF">BGZ80_005614</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>2 pyruvate + H(+) = (2S)-2-acetolactate + CO2</text>
            <dbReference type="Rhea" id="RHEA:25249"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:58476"/>
            <dbReference type="EC" id="2.2.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="11">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
        <text evidence="11">Binds 1 thiamine pyrophosphate per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 11">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 1/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 1/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the TPP enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.6" evidence="4 11"/>
    <dbReference type="EMBL" id="JAAAID010002763">
        <property type="protein sequence ID" value="KAG0004479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MJ74"/>
    <dbReference type="OrthoDB" id="16262at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005948">
        <property type="term" value="C:acetolactate synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003984">
        <property type="term" value="F:acetolactate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:L-valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02015">
        <property type="entry name" value="TPP_AHAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07035">
        <property type="entry name" value="TPP_PYR_POX_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1220:FF:000008">
        <property type="entry name" value="Acetolactate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000007">
        <property type="entry name" value="Acetolactate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012846">
        <property type="entry name" value="Acetolactate_synth_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039368">
        <property type="entry name" value="AHAS_TPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012000">
        <property type="entry name" value="Thiamin_PyroP_enz_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012001">
        <property type="entry name" value="Thiamin_PyroP_enz_TPP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000399">
        <property type="entry name" value="TPP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045229">
        <property type="entry name" value="TPP_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme_TPP-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00118">
        <property type="entry name" value="acolac_lg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18968:SF13">
        <property type="entry name" value="ACETOLACTATE SYNTHASE CATALYTIC SUBUNIT, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18968">
        <property type="entry name" value="THIAMINE PYROPHOSPHATE ENZYMES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00205">
        <property type="entry name" value="TPP_enzyme_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02776">
        <property type="entry name" value="TPP_enzyme_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00187">
        <property type="entry name" value="TPP_ENZYMES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 11" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="8 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 11" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="6 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiamine pyrophosphate enzyme N-terminal TPP-binding" evidence="15">
        <location>
            <begin position="87"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="Thiamine pyrophosphate enzyme central" evidence="13">
        <location>
            <begin position="292"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="Thiamine pyrophosphate enzyme TPP-binding" evidence="14">
        <location>
            <begin position="495"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="45"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="45"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0004479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="675" mass="72933" checksum="789D8B644335DBC9" modified="2023-09-13" version="1">MQTQPFARLARSTYSAISRQSLSKPLSLSSATRIAASQIRFRSSAATAESGQPNIATADPKAAPLEPLKPTHSKSSKPGHDHSFVGMTGGQIFHEMMLRHNVKHVFGYPGGAILPVFDAIYNSKHFEFILPRAEQGAGHAAEGYARVTGKPGVVLVTSGPGATNVVTAMQDALSDGTPMVVFTGQVAVSAIGSDAFQEADVVGISRACTKWNVMVKDVADLPRRINEAFEIATSGRPGPVLVDLPKDVTAAIVNKPIPAAPSIPARPPTSQAPFFSGLAKDASQVTSPQILRAAELINAAKRPLIYAGQGILAHPDGPARLKELSHNGNIPVTTTLQGLGAFDELDHRSLHMVGMHGSAYANLAMQKADVIIALGARFDDRVTANVPRFAPEAKKAALEKRGGIIHFEISPKNINKVVQATEAIEGDVTENLTKLLPLIESSERKEWFTKLGDWKRRFPFYHVQDPNGILLPQTVIQELDKQTADIKEKVIITTGVGQHQMWAAQYFRWRHPRSLVTSGGLGTMGFGLPSAIGAKVGKPDHMVIDIDGDASFCMTGMELATAAQYNIGVKVLILNNDFQGMVKQWQDLFYEERYSATRMFNPDFVKLAEAMNIKGIRATSMQDLPGAMAEFLAHPGPVVLEAKVCKREHVFPMAPAASSLDEFIVHPDQASESRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MJU1</accession>
    <name>A0A9P6MJU1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005592</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002752">
        <property type="protein sequence ID" value="KAG0004613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MJU1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="214"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="214"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="234"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="262"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="286"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="309"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0004613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="363" mass="37154" checksum="2BFB72B077E3DA2E" modified="2023-09-13" version="1" fragment="single">RTLSNGSSTAVSPRRAKVSSLAQMDISSVPYSPKSNPGSAPVASTNSSRGPSATYNSTNTNAPVRAPSVKVRTSNSVTATSPSRNPSGGGSTISSSRKDSGSVTSDDGTISEDSDLTRDEMLFTGGQANVGGGITLPFGTSKRPASIGGPVYGVGIKLGATTVSGGNGLSRHRSSSSIIGLSSGSIISGITPKPMRMAAGATIKIDSPNNHSGNYTSISSSHSSLGLSSAPGSTVGSQMSPNTTGLTSSATMPIWSTPSSPSLSRNGSFRRSGGGGGDDGSSTISVNSTNPHHPNVRSNKNIGSANIKQTEESRRNEEAARTRRKIQDLEISNSSLLNLNQSLETTNRKLVAEIQELKTRIQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MKU9</accession>
    <name>A0A9P6MKU9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005124</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002544">
        <property type="protein sequence ID" value="KAG0006829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MKU9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="119"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0006829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="264" mass="29749" checksum="D29F0F48FD1C96EC" modified="2023-09-13" version="1">MIPSTLQAHVQTLGDSSIPTKDPSQCRPDCIVIDSSECSPACSTAPDCASSKPVPTGNVQEPADRNSVPRNANPPLRASKSSGQSRGRVGRPRSSSGTSARPISVDSPKDSTSTDRPLEPTSSETPRNTTSTPPRRRKARQNSLWYLRYKSESPDPITQKYFCKGCPPGREYKYVNNSQLSRHATQHRFTGDRRRYHCFGCKDERKFCRMDALQRHMVKGEMYKECLERGLYSEYDEFGNGVLIEHPIPKQWRKPDPQKMDIDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MM16</accession>
    <name>A0A9P6MM16_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AAA-ATPase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_004683</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002364">
        <property type="protein sequence ID" value="KAG0007418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MM16"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34825:SF1">
        <property type="entry name" value="AAA-ATPASE-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34825">
        <property type="entry name" value="CONSERVED PROTEIN, WITH A WEAK D-GALACTARATE DEHYDRATASE/ALTRONATE HYDROLASE DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0007418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="397" mass="44503" checksum="F8CB81DABECC34F3" modified="2023-09-13" version="1" fragment="single">MTQSLNGHINDSLKDFCQSYANILVECEDDTPAIVDDCLTSLANTIRKVRLTGSKIYLLIDEYDAIARVTPLAMNGVTSGFNVRHDLTLLPRSKHLLGSMRRIFGERSRKFSDMSEDQKQTINSHVDQMREYYNGYRFAPIKNNDVYNTIYSTNLCLDYLQRLLKGDPLELADSNNGLNEGVLQFIGRHPDSLFLLAGLLENKETSCADIKSGIKLADLTNVEKMDKDHLKSFLFYVGGLTFSSSRDKFVVPNAVMTKAIIERVLQLCSISTNSDAHKEAIKNFFDSDDVEVPVPVVTSKRHYTTNEYIDLPLVETKPGQGKTPKRIVFEFKCKGVKFLDCGVGGMGSWEATEERASHIASLMDEELMGIKCDVSDKNDHGKTMKQLLDNAAEKLKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MME9</accession>
    <name>A0A9P6MME9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_004762</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002397">
        <property type="protein sequence ID" value="KAG0007347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MME9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050562">
        <property type="entry name" value="FAD_mOase_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356:SF2">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356">
        <property type="entry name" value="FAD-DEPENDENT MONOOXYGENASE ASQG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="132"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="265"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="273"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0007347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="285" mass="32413" checksum="C245C99EECEAB085" modified="2023-09-13" version="1">MYKELEEQGSLPLVDKEALSIGYVTMVGVSKPVNPEKYPQLAEKYRSYFHVTIGDNNDSCYLVTTLDNQISWGIQIQIPEDKAKEQQFRNSEWGPESVDEMLDQFRDFPCAFGGTMKEIFDATPRNLISKVFLEEKAFQTWYNGRSVLIGDACHKLLPGGGQGAVMAMKDAVVLANCIYNMKDLSDESTKAAFTSYYRQRYPEADDVTRTSSVFTKVLCGHKWSDRLVRKIILNYLPGCIRMKIAQDTLMIRPQINWLPLTKSRGSGRVLPQEGREEAERKARAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMW8</accession>
    <name>A0A9P6MMW8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_004356</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002229">
        <property type="protein sequence ID" value="KAG0007688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMW8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="2">
        <location>
            <begin position="38"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="515"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="596"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="605"/>
            <end position="622"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0007688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="662" mass="74374" checksum="B2BC5BD7B99402E7" modified="2023-09-13" version="1">MSISSPASNSPVLSPEPTPAPMSHLSASRVLFEEGLYSDITLTLQVPGSLKKILHLHSRILSRESEFFANLLSGKENPNEKAIVLLEERDSNGCQVIEVQCINATELYAIESSLRLLYTGSWCSDRDFQTSSLDARIRRGMDVMNQAARLSLKGSTKALLQDEITQMCQSQPELMEKLSRSLRPEDREDDQAILHFDKDALQQMCKVAVVKPEIRDHCELVIARNLYGPKKFRDLRMSEVQLSELRHGYIFPPGGQESIYLLKGAPSLPLHPCRASNVEALRQVVDYYTAYNSQQPLRRREYYVIPNEEDGAAPKSDAPVVTYYKITFTSAYHWLLDQVIKVRAPFELIILLLKDAVDENADSRNNVYFGEFATSQDGDAYLQGVNYIADGLLHAFRDPTLESFRNPGASGSLLNMISYGVSSLTDLPPLRERPKSKSGDAGAAHQEYPALSTLVIEFFWQVLQLALKRPHHLEFVQLLLDSITKIAPLAPFEVLDRIEERLAELLEETRKKIMEQRGDTQGDGEAGDAENDNKSEASEDEIDVKPVRARTISGVARSEVSSGRLDDIDERTSMVSSVLLASEVSHVTKNAHIITKDDDASSMQQEEEEEEEAEPEAEAEAEVEVPWMRPEYLQPLCLQLLTKFPMNIQSSLLWAIHDLQLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMW9</accession>
    <name>A0A9P6MMW9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ketoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_003689</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001998">
        <property type="protein sequence ID" value="KAG0008215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMW9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000173">
        <property type="entry name" value="3-oxoacyl-[acyl-carrier protein] reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760:SF133">
        <property type="entry name" value="3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketoreductase" evidence="5">
        <location>
            <begin position="7"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0008215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="239" mass="25683" checksum="D3995A4EAA3B8A2B" modified="2023-09-13" version="1" fragment="single">MHSPFLHSYIPAGGTRGIGLSTAKLFALNGSRVVILGRDQDRINHVLEKELVPISSSPSEGHMGFKCDVSRQVDIEHTIKEVSKIAPVDHLVMSAGISRDSLLMAHSLQDMEEVINTNLMGTIWVNKAVAKGMMRRKKGAIINISSVVGVQGNIGQTIYSASKAAIIGFSKSLSRELGSRGITVNVIAPGYIDTDMTSSISEDRKKDIIAKTSLGRLGKPEDIAEAALFLAQAKFITGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MN35</accession>
    <name>A0A9P6MN35_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Oligopeptide transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_003688</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001997">
        <property type="protein sequence ID" value="KAG0008217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MN35"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035673">
        <property type="term" value="F:oligopeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045035">
        <property type="entry name" value="YSL-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31645">
        <property type="entry name" value="OLIGOPEPTIDE TRANSPORTER YGL114W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31645:SF0">
        <property type="entry name" value="OLIGOPEPTIDE TRANSPORTER YGL114W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="35"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="141"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="278"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="304"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="336"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="381"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="462"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="494"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="545"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="604"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="643"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="698"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="730"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0008217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="730" mass="78944" checksum="945EEB282F775110" modified="2023-09-13" version="1" fragment="single">MTTSPGPQPGNNAQGQELEPTRISEDYPQQDLPHFTLRAVVVGIVIGTLLCFTNMYFGLQTGWISMMSLQSSLLGFAFFKALKHYLKVPFGSAENIVLQSVAVATGTMPLAAGFVGIIPALQLMTTSDNPATETSPGGPVFLSAGQMILWSLAVAFFGVFIAVPLRKQVVIKEKLPFPSGTATAQMIGVLHNTPLVVRSPVRNVSSEYTVESSQLEGGLRKRKLALDEVPPQQPLGQIAPVDYVSKEEIESIEIKGENGEHFTLSQNFLQEDNWKTNMTALGLAFGASALYTILQYFFPVVSTVPIFDWLSGMTVTVAGTWQWYFTPSLSYVGQGIIMGFPTTASMLLGCVVGWAILSPVVTHKGWVTGAVSSSTNGARGWILWVSLGVMIAEAVVSLLGVIVLSLIAHYRRSVREKRRAERRAALEASASQTGANVDAFTEEEEDLEDDDAPIDQLVPLKIWVCGLILSSALALLLIWIVFRGQRMPVYAGKVSQFIFAGVVPGGIVANIVAGGIAEAGAQQAGDLMQDIKTGHLLGASPKAQFYAQLIGSLASVFISTGVFKLYASAYELPGPQFSVPTAKVWLDLARLVNGHSLPSNTSPFIWGFAIFFAVLTLVNVYYSDTAFLRSRGANGSVRGRPRWLNYIPSGIAFAIGMYNLPNFTLARFVGGLVSVWWDWHCKKYANHPTAKYAKLGRVFLIIIASGFVLGEGIFSIVNLILKTANIHSTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNL9</accession>
    <name>A0A9P6MNL9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003989</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002090">
        <property type="protein sequence ID" value="KAG0007988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNL9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="31"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="71"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0007988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="95" mass="9517" checksum="E3A1A46F4BB14059" modified="2023-09-13" version="1" fragment="single">RTTCARCGANAPNQGGPSGGNGGGPGGAGGSNANYYGTQHHAPPPQQPAPVQTPGYSPMNPSFGSYGGPTYGTQPPQQGYGSYGTQQYGPPSNRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPD2</accession>
    <name>A0A9P6MPD2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_003539</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001940">
        <property type="protein sequence ID" value="KAG0008364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPD2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0008364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="485" mass="54362" checksum="8324B745E5FBE775" modified="2023-09-13" version="1">MAKGEADLAIRARCKELKQQNRRFVVVTTDSDPLAPEAVPTIYRPIRRGFLRYDVDQRATDLGVSCRQLTALAIVSRNDYSSGPFCLDLGINTEIIKESAAPKKSVSNIIDDCLKNDTVKNRFKKTSLEIEGLYQPSRKVYLLGSETPIDDKGSIEDAKIHKAAKALSLRYKDAKITMAANSKAKREEAQEAKVKSIIPPGHVPWMVFNQYWTIDKASLPSQDKTSTSTSDRYVNQPIGVRQGKYTCRYAVKIHDCSQPSSPSVSVPDSFKRSKWKAYVEREYSKPEEETSKKKKYQPSRRIPSCRYDLVKAMIKARQAATLTVGSLATNRKKLDDLTEDEKTAIGKLIQDCVNIGNFVKREAHIALASGGEGNEGLENIRKALPKYPDDIEGDEEDAEFSRADSTKIFQTLSTFVTFSDNEGKSYTKENAIIPVILFQSIGNAIPVQYKRCFQETRTDKNSRPPVAPIGNSFILLTEGEHLRML</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPZ1</accession>
    <name>A0A9P6MPZ1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_003049</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001786">
        <property type="protein sequence ID" value="KAG0008793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPZ1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039712">
        <property type="entry name" value="Meu6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039483">
        <property type="entry name" value="Meu6_PH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42073">
        <property type="entry name" value="MEIOTIC EXPRESSION UP-REGULATED PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42073:SF1">
        <property type="entry name" value="MEIOTIC EXPRESSION UP-REGULATED PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15406">
        <property type="entry name" value="PH_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="36"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="287"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="394"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="558"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="302"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="394"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="436"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="475"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="571"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="586"/>
            <end position="596"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0008793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="612" mass="65928" checksum="32CBEB14EA59DA32" modified="2023-09-13" version="1">MTKKEEVVAEIEATETPAAEVSTTSKTEEEEEEEDIDIEGGYLQKRGTNPLNPWNKRYFTFGTEPVSLDNLKTVHKRNEHRVKKVPTPPAPEPTSEVAAGKAPAKDEPAAAAPAPKTVEEVYEDANRDLLINVAQANTKGTGLLYYHKSDDELHRQNILGIINLRDVNSVERVEKTSKSRSFTVSTKNRDYHFSAESPQKAKGWVKAIKEKAEEAKAEEDPYGSPQFQEVYKKLVAREAFEHAKNSASIIADNEINSDGEPDDIEIENGTPIVKKRKSFFGFSAVATSHEKKKADGITTEVSTEKKEEITHVQDGDVDALKTHESENAVSHTTDAVAAPAEPPKSPKAKSGGFKLFGKKAPKAEEAPAAPAEHPLTVDEAKAQALKAVDDAVEASKAKAAEAKTDAPATPPAPEKKPGFLAHLFGKKPAPAPAAPVVPNEETVVVSSEKTVSDVVTADGEVTSESTGGFFSRVTKGKDKNEVEVKSGEVTTEDVINTEGSTHVEHIEGTDASVANENGEQRVDLSTTDETIATADTAEKIERKPSLLKRLSGAVRKATAPASIEATTQVEETVEEETVAETEEVVEETKVTEVKEEEVTTEVVAEVSAEAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQ55</accession>
    <name>A0A9P6MQ55_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_002215</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001540">
        <property type="protein sequence ID" value="KAG0009625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQ55"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0009625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="177" mass="19884" checksum="577BEFE828C19887" modified="2023-09-13" version="1">MASSTSGSSWKSYHSSRVPGSANSFGNNPNDDQDLDENGFGEYERLLARRRSTSYYDANRSRAPVAVVIKHDSKGRPISTWSTASSVAAQRGEELSQWSKRRDDLLKIYGRNNTNSGSFVNYDDLEEEPEQEEEAESQEQEQEERHEPDYSNKAATVTEEGRNDNGQSHDGISSVRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQI9</accession>
    <name>A0A9P6MQI9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">SAT4_2</name>
        <name evidence="12" type="ORF">BGZ80_001885</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JAAAID010001444">
        <property type="protein sequence ID" value="KAG0009984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQI9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030003">
        <property type="term" value="P:intracellular monoatomic cation homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13994">
        <property type="entry name" value="STKc_HAL4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24343:SF558">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24343">
        <property type="entry name" value="SERINE/THREONINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="268"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="570"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="113"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="128"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="301"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0009984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="622" mass="69321" checksum="117F4196225D1C74" modified="2023-09-13" version="1">MDVTDKALNNLDHDPINPVDNNIHISVEHPASDPQPSLQDGVSHLSLEESIPSSPKPKQLSPLSTLTITSTATMPDCSLPPAPSPQPRQRHHTDQPDSIQRPTPIPLRPSSARGRSSYNNSQLATVISSGPSAPAGPSRASPSSWSTASSETTPSSGSSSVIDSKYRFEKLPNGGHRHHLSAPRRQQFLSNQVRWLKELIEGKKDREENTAAPQSQGSHQLKPEVFENPLSLLNEKYQNLDADQTGSPVANNRLKYALKSDFVQKYGELQQQVIGKGASGTVRLSIKRNPETGEEHAYAIKEFKYPYGESQKQYMRRLTSEFCIASSLKHPNIIQTMDLLKLHEDTYSEVMEYCVGGDLHSLIAAANSLGELESNCFFSQLIHGVAFLHSVGVVHRDLKPENLLLTSDGCLKITDFGNSEVFRMPWEKKVRSSASIRGSGPFIAPEEYTTETFDARKVDMWACGIIYMCMRLGKYNWHEATDGDPIWDEFLYKRERLLEQQQNASNSGQTPKHLNLTALEQAAHITLGWPHYISDVIEKILEPNPRKRSQANHVLDSEWLKRIENCHPTARPPKQVLDESDFEPSIPSQRVGSRVVRADSPAVTGCKIVKEARDRQKPTLGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQT5</accession>
    <name>A0A9P6MQT5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Vacuolar protease A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">PEP2_4</name>
        <name evidence="7" type="ORF">BGZ80_002102</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001508">
        <property type="protein sequence ID" value="KAG0009751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQT5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF51">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase A1" evidence="6">
        <location>
            <begin position="77"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="138"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="13"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="168"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="186"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="196"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="215"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="108"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0009751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="642" mass="68633" checksum="7E0F78032CF49345" modified="2023-09-13" version="1" fragment="single">HGGTARVDAFPVSRTSTESTNPLSSPSTVSSGAVLIPLKRLITKRLDSAQLPSNAIQKRGVPTTSTALVTQVGAVGYAGHILMGTPPQRLAVLFDTGSDLVLVTSDRCQGSECPELTHFSCSTSTTCVDLGGESVGKVGNESASTENVGGKANSQVANKSVSRHAHTNPKSNRNNESPTVAPHLQLTPTASSISSKSDEDQMRESGSETLSSTSKTKENAMDSHVIHPTKRLERPEGETKIKDNDRLLEGVHSDVNPTSTSDDIIKSPSSQPPPPTPSTNFYNQSYEDGSWGAGTFVQDRIQIDTTPASEVYNPSPSPQTIDLQRTATITFLNVVQDSLDLVQGYNGQISGLLGLTRASPTGHKTFLQELVEQGSLPQPVVSMNLETEGASFFFGGINQSQYTGELVYSPVTDPINWQISLQGLGTRVKDAASTFSTLSLGLKKGTGVGIGAGDGFKMMPHMENLQGAALVLDSGTSFILIPSAASKVIHTELSGTWDPLHQAWFLPCTGPDLVWWISLYHAVVQPYESLVYPLEDGQCQSLIFENGNADFWILGDNWLRGLYVVYDMDGDGRIGIAGAVNPEANEFTSGSGANAPRARIMTFRNPNTGLRLRSILAGNVGSRLVATIVWTALVNWLFIAFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MR64</accession>
    <name>A0A9P6MR64_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 9">Triosephosphate isomerase</fullName>
            <ecNumber evidence="6 9">5.3.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">TPI1</name>
        <name evidence="10" type="ORF">BGZ80_001293</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:18585"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="5.3.1.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 9">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate from glycerone phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 9">Belongs to the triosephosphate isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.1" evidence="6 9"/>
    <dbReference type="EMBL" id="JAAAID010001293">
        <property type="protein sequence ID" value="KAG0010646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MR64"/>
    <dbReference type="OrthoDB" id="6715177at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004807">
        <property type="term" value="F:triose-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046166">
        <property type="term" value="P:glyceraldehyde-3-phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019563">
        <property type="term" value="P:glycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00311">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000025">
        <property type="entry name" value="Triosephosphate isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00147_B">
        <property type="entry name" value="TIM_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035990">
        <property type="entry name" value="TIM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022896">
        <property type="entry name" value="TrioseP_Isoase_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000652">
        <property type="entry name" value="Triosephosphate_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020861">
        <property type="entry name" value="Triosephosphate_isomerase_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00419">
        <property type="entry name" value="tim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21139">
        <property type="entry name" value="TRIOSEPHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21139:SF2">
        <property type="entry name" value="TRIOSEPHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00121">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51351">
        <property type="entry name" value="Triosephosphate isomerase (TIM)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00171">
        <property type="entry name" value="TIM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51440">
        <property type="entry name" value="TIM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="9" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="8 9 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00019397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0010646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="249" mass="26879" checksum="448305AB0DD3579D" modified="2023-09-13" version="1">MPRKFIVGGNFKLNGSQDSLATLVEGLNKGSLDSNVEIVVSPPFVYLDQVRKSVRKDVAVAGQNCYSKASGAYTGEVAAEMLKDLGIEWVILGHSERREIFKETDDEIGQKVAHALKAGLKVMACVGEKLEEREADKTTEVVFRQLAAVAKHVSDWTNVVIAYEPVWAIGTGKVATPQQAQEVHKAIRGWLKEKVSAQVAEATRIMYGGSVNAGNASTLAKEEDVDGFLVGGASLKPEFVTICNAKAKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MR84</accession>
    <name>A0A9P6MR84_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_001446</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001329">
        <property type="protein sequence ID" value="KAG0010486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MR84"/>
    <dbReference type="OrthoDB" id="4748970at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031519">
        <property type="term" value="C:PcG protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000007">
        <property type="entry name" value="Basic krueppel-like factor 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR PROTEIN YY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003:SF19">
        <property type="entry name" value="YY2 TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="496"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="526"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="557"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="79"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="136"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="243"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="315"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="433"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="7"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="31"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="91"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="329"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="433"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0010486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="582" mass="63464" checksum="3DDA282AC6F89D94" modified="2023-09-13" version="1">MEHSHNQQQQSEVESTASSSTAVNYNTQYGPSSSSATPSGMSVPLVYPLLAEALVREGFPGFASVLAFTQDQRQLEQALDHHPYSSSSGYQQDQHIQQQQQLQQQPHHHHQNNLQDDSYLLDFVVQEHNMLMAQHGYNGSSSAASSSSTPYPQGHAMQSSDPALHDPNSPYNIMGEMQPFEVMQYNSLVLDGHYLDALPYSIIQGGCGGDSPGMDTPGWCDPSLAGANYIGEQYPQQINIHQMSQPQQQFQQGYFDPSLSSGSSTAGPSSAGSSSSPSGPASGYGFNYPAWSAAHAGLLYPQGDFLLERKREGAAGIPRTTVQPHLEPAEEDDDSDEDDDDDAEEFGEVEDEAPGMLMPTEHYGFRSGNYPVDDLHVPPLTGRSARRPSYGQKNDRDDDRMIGAPSSKRSRSDATTTAAAVAAAAAAASVAAQRRASSGAPGSNHNNHSRNSSMSSINSHSSLLDNHSSSTSSSSSSSPNGKAPRQQVDTIEKRMHPCTVAGCHKSFTRAFNLRSHLNTHNGERPHKCPEPGCDWDFVRRHDLDRHVKSKHMANKPYACRQCTSRFGRSDALQRHRRLENHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRE7</accession>
    <name>A0A9P6MRE7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_001558</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001359">
        <property type="protein sequence ID" value="KAG0010352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRE7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0010352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="312" mass="35139" checksum="EA1780566804F810" modified="2023-09-13" version="1" fragment="single">MARHGREHLSLVYLNLIFDPPGLQSLNGPRHDNDHAHIKDIQIVPTQAELICERSPYLPSNDIPGAPHHLPPGWSRLLDIHFRLNREDMIDQLRQGIVLFLGALSKTTPGNRGDLFTRNRLRKLMGEDVSVNAYGNVELLGANVDSQLRGSIKVSFNQPQKIKGRPKKERKDFWERSRRRLIKNSLVCFIYPEEGQDNVGVQGRSNGELRLFLGVVDTKDIVEMAEDANKAVVHVTMIDDADYCQLVRAVKKGVVSPKDVFMVESLGGNFESYRPILRALQMLEPDTMPFSKYLAPMEGQPTSDSVTLISPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRZ5</accession>
    <name>A0A9P6MRZ5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_000755</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001164">
        <property type="protein sequence ID" value="KAG0011349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRZ5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="318"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0011349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="477" mass="54056" checksum="C6D3244B8060EC4D" modified="2023-09-13" version="1">MTKHKPGLDDFVLDFFKAHPTLQDISFEFETITPALIATLDKRHLPSLKSFGLFGDDRIMDDASVQQLIHACAWLETLEIEIRREEDRREKQNADLYQERKTIMESMPTTRLRNLSIDLHCPFQEAVTLVPLLRKSPLLQELCIRSSPGNNTSVSIAAALREEGCCPELKTLTIEQEGIPDNELAELVNACTNSLCLSKSYESPLTRATFDKVHRDLKSLTVISKACGPLTACSLTQDCAQSLVVLDIGQYKFIYLGNFITLVSNLLGLQKLFVGNIYFVSLAQGGKNSLVNALETPWVCRDLKCLDFHLFWSNAKESFSDDDSGSEGDGLRRYTTAKSTGGSDTDDMTDLADFRSRCLDCFWDRVAELGNLRYLSYKSKEFPLLPRPRNSVFYLDRLRSLKKIQTLHIDFDILGVKEAAWILLYWPDLSRITGLEREHAEMCPCRSRSSTWICTRPLEEGEGMTVLKTGRPWIILD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MS33</accession>
    <name>A0A9P6MS33_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Probable glutamate--tRNA ligase, cytoplasmic</fullName>
            <ecNumber evidence="3">6.1.1.17</ecNumber>
            <ecNumber evidence="4">6.1.1.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Glutaminyl-tRNA synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Glutamyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">BGZ80_000677</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>tRNA(Gln) + L-glutamine + ATP = L-glutaminyl-tRNA(Gln) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:20121"/>
            <dbReference type="Rhea" id="RHEA-COMP:9662"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.18"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>tRNA(Glu) + L-glutamate + ATP = L-glutamyl-tRNA(Glu) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23540"/>
            <dbReference type="Rhea" id="RHEA-COMP:9663"/>
            <dbReference type="Rhea" id="RHEA-COMP:9680"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.17"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.17" evidence="3"/>
    <dbReference type="EC" id="6.1.1.18" evidence="4"/>
    <dbReference type="EMBL" id="JAAAID010001145">
        <property type="protein sequence ID" value="KAG0011455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MS33"/>
    <dbReference type="OrthoDB" id="10250478at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004818">
        <property type="term" value="F:glutamate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004819">
        <property type="term" value="F:glutamine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006425">
        <property type="term" value="P:glutaminyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1160.10:FF:000001">
        <property type="entry name" value="Glutamine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.240.10:FF:000007">
        <property type="entry name" value="Glutamine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.800.10:FF:000001">
        <property type="entry name" value="Glutamine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.2420:FF:000001">
        <property type="entry name" value="Glutamine--tRNA ligase cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.1290:FF:000002">
        <property type="entry name" value="Glutamine--tRNA ligase cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000037">
        <property type="entry name" value="Glutamine--tRNA ligase cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.1290">
        <property type="entry name" value="Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.240.10">
        <property type="entry name" value="Ribosomal Protein L25, Chain P"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004514">
        <property type="entry name" value="Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007638">
        <property type="entry name" value="Gln-tRNA-synth_Ib_RNA-bd_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007639">
        <property type="entry name" value="Gln-tRNA-synth_Ib_RNA-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042558">
        <property type="entry name" value="Gln-tRNA-synth_Ib_RNA-bd_N_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042559">
        <property type="entry name" value="Gln-tRNA-synth_Ib_RNA-bd_N_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050132">
        <property type="entry name" value="Gln/Glu-tRNA_Ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000924">
        <property type="entry name" value="Glu/Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020058">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020059">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_codon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020056">
        <property type="entry name" value="Rbsml_bL25/Gln-tRNA_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011035">
        <property type="entry name" value="Ribosomal_bL25/Gln-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049437">
        <property type="entry name" value="tRNA-synt_1c_C2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00440">
        <property type="entry name" value="glnS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43097:SF4">
        <property type="entry name" value="GLUTAMINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43097">
        <property type="entry name" value="GLUTAMINE-TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00749">
        <property type="entry name" value="tRNA-synt_1c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03950">
        <property type="entry name" value="tRNA-synt_1c_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20974">
        <property type="entry name" value="tRNA-synt_1c_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04558">
        <property type="entry name" value="tRNA_synt_1c_R1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04557">
        <property type="entry name" value="tRNA_synt_1c_R2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00987">
        <property type="entry name" value="TRNASYNTHGLU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50715">
        <property type="entry name" value="Ribosomal protein L25-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 15" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 15" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 15" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutaminyl-tRNA synthetase class Ib non-specific RNA-binding" evidence="19">
        <location>
            <begin position="6"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="Glutaminyl-tRNA synthetase class Ib non-specific RNA-binding" evidence="18">
        <location>
            <begin position="166"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic" evidence="16">
        <location>
            <begin position="251"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="domain" description="Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding" evidence="17">
        <location>
            <begin position="561"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA synthetases class I (E and Q) anti-codon binding" evidence="20">
        <location>
            <begin position="675"/>
            <end position="769"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00070830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU363037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF03950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF04557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF04558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF20974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAG0011455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="809" mass="91171" checksum="3091BE64FF830017" modified="2023-09-13" version="1">MPNDSILILFQNIGLTESKAKETVKNKTLAPTLEKAIFAAGFDNTPCESTGALIYALASTIGNTPGAIPHLDYLAIAIRDSKLETTDQVAAAIRFVSDKNEIDETLFNKECGVGIVVTKEDIVKAVNDYTKSVKDKLIKDRYKFFGAYFGGVKKIPSLKWANGGEIKEVVDSKVLEILGPKDERDAALKKKLEDTSKEVELTIATAATVAREIPAMFTEGELSKLHLPGTNPQIKPELMEEHLRATGGKYVTRFPPEPNGFLHIGHAKAININFGLAKAHDGICYLRFDDTNPETEKESFAESIIETVKWLGFTPAEITYSSSYFPRLYELAIELIKLDKAYVCHCTAEEIQMHRGGPERGPRSACVHRDRPISESIELFEKMKNGGFEEGEAILRMKMDLENGNPQFWDLVAYRVLKTPHHRTGTEWCIYPTYDYTHCLVDSFENITHSLCTSEFAQSRASYYWLCDALEVYKPVQWESGRLNVQGTVLSKRKIAELVRRGHVMDLDDPRLYTLPAIRRRGVPPEAVNNFIHNLGVTKADTVIEIARLDSYIRDYLNNTALRLMGVMNPIKVTLENLPEGFEMSVTVANKPRDPSMGERTIPFTREIWIDGSDFKEIEDKNFYRLAPGRSVGLLNVLCPITCTNVIKDPNTGRVVELKARYEDGEGFPRPTTYIQWVAESPKHGSPVRVDEVRLFDNLFRHKNPLSISEVPEGYLSDINEDSMKVERNVFVEIGIWDLMDRWAKASVSGTDYEAIRFQLTRIGYFCLDRDSDLGEFRDPTGNGPLQETTKKIVLNRTVGLSVSRTLNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSD2</accession>
    <name>A0A9P6MSD2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_001064</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001236">
        <property type="protein sequence ID" value="KAG0010943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSD2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23507:SF1">
        <property type="entry name" value="FI18259P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23507">
        <property type="entry name" value="ZGC:174356"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="112"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="176"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="214"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="243"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="339"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="375"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="417"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="443"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="476"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="510"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="44"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="281"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="8"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="281"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="293"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0010943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="543" mass="58288" checksum="DE6A210ACACA944C" modified="2023-09-13" version="1">MDVDEPTAAETTALLAPSSDSPGPKSDLHPSPWYWPWQASHRAAIPVILLAGLSIGPARALTAPLIKALFCERGIPMYFPIQNNTNHLSSLSSLSLLSDPLDNNDQCDSAEYSAAIAEFIGINASLTSILVALTVRFWSALGDRLGRKRVMLVWAIGTVIAQIMPLLIYYNKSMSIYFIWVGSMIEGVAGASLSLIALTHAYAADVTRPEERTVAFGQTIAGWYAGLGIGSALGGAIVNEFGLIAAFWLMPVLVVIDIIYITLIPESLTVAAQTNDRSAKTMMTSSQSQSTTISVESSDNLDTSSASGSKESHPHCVEVFIKSLMPEQLPNRLGGEYSVVLLMVTCFLVLVAVIGASYQISPYLLYQFHWPSAKLSYVGAIQGLSRLAALTLLLPFIKRRAPRATISDPASSISFDLRVVVMGTLIEALTMLLYGVTSIGEGFYLGGMTGAVGSLFFPAIRGILSQSVASELLGKTLGTLATFESVASAISPSLFAWIYGITLETHPPAVFYIATVPTLLASALAAYVLVIHKREMRHRAWNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-06-18" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSE8</accession>
    <name>A0A9P6MSE8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">TATA-binding protein-associated factor mot1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Modifier of transcription 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">MOT1</name>
        <name evidence="15" type="ORF">BGZ80_000443</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001092">
        <property type="protein sequence ID" value="KAG0011758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10252227at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017025">
        <property type="term" value="F:TBP-class protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17999">
        <property type="entry name" value="DEXHc_Mot1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10810:FF:000009">
        <property type="entry name" value="B-TFIID TATA-box-binding protein-associated factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000428">
        <property type="entry name" value="TATA-binding protein-associated factor 172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000357">
        <property type="entry name" value="HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044972">
        <property type="entry name" value="Mot1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044078">
        <property type="entry name" value="Mot1_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022707">
        <property type="entry name" value="Mot1_central_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36498">
        <property type="entry name" value="TATA-BINDING PROTEIN-ASSOCIATED FACTOR 172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36498:SF1">
        <property type="entry name" value="TATA-BINDING PROTEIN-ASSOCIATED FACTOR 172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12054">
        <property type="entry name" value="DUF3535"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02985">
        <property type="entry name" value="HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040154720" description="TATA-binding protein-associated factor mot1" evidence="12">
        <location>
            <begin position="23"/>
            <end position="1874"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="13">
        <location>
            <begin position="1286"/>
            <end position="1459"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="14">
        <location>
            <begin position="1640"/>
            <end position="1801"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="49"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="147"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1816"/>
            <end position="1843"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="55"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="169"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00073046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00081329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0011758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1874" mass="207765" checksum="96A9ED6DB4ABFBD0" modified="2023-09-13" version="1">MSFRSTRLDRLVLLLETGSTAAVLVHLRSKSWDTRIAAGQALEAIVRNVPQWDPSDGKSKTQPKTEEGAEQKPASEQPKYDRLSFSNFDISQVLQNGKLLLGSAGKEYDLDLSDLDPAERLAIQRKNLAANLGLMTSQFMDVDLVDESDISGPKTPATPVKQEQPPTPTTSTSSRQPLSSPALPNDVDMEGLSARERNKLKRRAKTDLKFKGKDKVRVIDLAGRRKGPDTPGTPATPAIGPDGQEGGYFEFTPQSDSNKVVVEAKLPMQSVLETSTEWPFEGICDLLCMDLFDPCWEIRHGAGIGLRDILKVQGSGAGRVIGCTKAENDARHNEWLEDLAIRLLCVFSLDRFGDFVSDQVVAPVRETCSQTLGALLRHMSDESVKSTIGVLMRLIYQNDVFEESMERDYIWEVRHAGLLGLKYAVAVKKDILDDDSTYAAHMLENVVNAVVLGLKDEDDDVRAVSASTLIPISSNFVNKLPERIPDVVNILWDCLAVLKDDLSASTASVMDLLANLFSFQRVLDSMLHAKDESHSLVNLIPRLNPFFRHTIPSVRVAVLNAMQTFLQLKSIAEWVDERVVRMVFQNLMVEEKKDILDLSLTVMKALIEHMSASESSSLITTVAGPHIQSFFTSLLTPIGTPLDTRLFYSPSGHVIPVVVEAPSRGRKAQAAAAAAQSHSHNVDIGMLKQDLALVSTESVIRCRLSASKALGLIMAGWPQDQLEASFYHILQPNFTSPWAMRRQMSAIVVAEWSLAFKERVGAYPTESRLGFALITSAALTECLVSDPPLSYMESITVLKGIRAEIQAMLNSFVADGKLSPSSIPALPQVASMTDNGDGSNFTIDYAREFAVAVPSLMNQISSRSRKTAVPLLTSRHERIIASIGYFESIKEKADLYVAAAVGSAVINLGTLPAKLNPVINSVMKSVRSEENIELQTRSAATLASLVILCNSPFCDLRVAPTPKLIKNLGRYLCGDTTITPSLDQDSSMEGIFSLKKSKETAADAKTLTGHGMEDVKISAKDTKIVEDEETKLTRRGAVAAFKEFAHRFGPNLFTAVPKVWECMSAPLTEAFANEPIVAPTGLDADGWHNAIDALEIIKTLVPHIHSDLYPSIEQLMPHIATALLSPFTVVRHAAAKCLAVICNVITIPGMHLIIGKVVPYLGDTVNVIRRQGAAEMINEVVQIMDAKILPYVVFLIVPILGRMSDPDEPTRLVSTNCFAHLIKLVPLEMGIPDPPEMSAEMLQQRQDERQFLMQLLDSKKLQPYSIPIKIKAELRKYQQEGVNWLAFLNKYQLHGILCDDMGLGKTLQSICMLASDQHDRQVKLKETGFPRYAHCPSLVVCPPTLTGHWFHEILQYTDNLKPMMYTGGPADRKRLRSSIPKHDVVIMSYDVVRNDIEDLEKIHWNYCILDEGHIIKNGKTKITRSVKMIKANHRVILSGTPIQNNVLELWSLFDFLMPGFLGTEKQFNERFGKPILASRDCKSSSREQEAGVLALEALHKQVLPFLLRRLKEDVLSDLPPKIIQDYYCELSDLQKQLYEEFSKSQIKHEMEEELTTETKDDPPQKATHIFQALQYLRKLCNHPLLVVNENHPEYAKVMRQLKSQNESLHNINFAPKLQALRQLLVDCGIGSKPVAESNADIEASLIGGGESAVSQHRALIFCQQKAMLDIIESDLLRPLLPSVSYMRLDGATDASRRHGIVQKFNADPSIDLLLLTTHVGGLGLNLTGADTVIFVEHDWNPMKDLQAMDRAHRLGQKKVVNVYRLITKGTLEEKIMGLQKFKLNIANSVINQQNAGLQSMGTDQILDLFQISGDDETDGKKKGKGKGGFSDPNANGGEDQKMSTKNVLESLEGLWDEKQYEEEYNLDSFISSLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MST3</accession>
    <name>A0A9P6MST3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">E2 ubiquitin-conjugating enzyme</fullName>
            <ecNumber evidence="1">2.3.2.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">UBC2_1</name>
        <name evidence="10" type="ORF">BGZ80_000339</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.23" evidence="1"/>
    <dbReference type="EMBL" id="JAAAID010001069">
        <property type="protein sequence ID" value="KAG0011906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MST3"/>
    <dbReference type="OrthoDB" id="7851174at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd23793">
        <property type="entry name" value="UBCc_UBE2E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000003">
        <property type="entry name" value="Ubiquitin-conjugating enzyme E2 E3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24068">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="9">
        <location>
            <begin position="24"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="6">
        <location>
            <position position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0011906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="167" mass="18591" checksum="C0472ED2B0A342DB" modified="2023-09-13" version="1">MSSSTARTANTTLKKKTATSSLSSSAKRIQKELAEINLDPPCNCSAGPKGDNLYEWVSTIMGPSGSPYAAGVYFLDIHFPQDYPFKPPKIVFRTRIYHCNINNQGQICLDILKDNWSPALTISKVLLSICSLLTDANPHDPLVASIAHQYLNDREEHDRIAKDWAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MT05</accession>
    <name>A0A9P6MT05_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Homeobox domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_011785</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000992">
        <property type="protein sequence ID" value="KAG0012382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MT05"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052145">
        <property type="entry name" value="Mediator/Homeobox_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24330">
        <property type="entry name" value="HOMEOBOX PROTEIN BARH-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1 2" id="KW-0371">Homeobox</keyword>
    <keyword evidence="1 2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="4">
        <location>
            <begin position="101"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="1">
        <location>
            <begin position="103"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="160"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="353"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="453"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="573"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="672"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="194"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="370"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="457"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="592"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="674"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="693"/>
            <end position="707"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0012382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="825" mass="90533" checksum="A7533ACE41CFFAD1" modified="2023-09-13" version="1">MASVTLSSPPSRSDSLTDEDEVMAHDPSKLPMSPPLSQESLLSSELILQGDHLQQQQQKQQQQQQQQQLIHPLDHSSLTAPKKTLNWVNALPSHFDTAVSGHPRKRRRRTNREELEILEDAFARNLLPDAATRQELGDRLGMSVRAVQIWFQNRRQTLRKKSISSSGVHNPGSEEDMSRSDAESAHSLCRRSSGDSAMSLSPTLNPTEAGHLLKRGSKSCSNLLSGSPPSSSTQLGSKLLRAETCSSLPTSVSAMSSTIKTPSMRSSSPIEHQIKQDISSEVAMAAAPRMVAVKTEVVEKSPRELLAAAAATTAAATTPAASGIQDILDVKTADRHLCMLLEEAKRRSGQNATPVMGIWSDTPSKPVLNPSSTGAFPTTTTFPTPKRTMSTPTMRSATSASQCRNSSSQHFRSTNLKIARKHRSMPESTISNSVMHPSSPYPRTVSLMEQVINRQQQQHHHHHQQQQFHKRPAPTNFKQSALSSAGKYSLDSICNKAMRSTPPAITANPSTALSATQLARRLQYIVRSNLKRVQSESVIHDLQKANNNGGGGRYGQTAMRARRLSFGKFLFDSDTEEESREEKSKDLRMITSSQQQQQHQQPQQRFQHSRSEVKLTHQAQKRRAGSTMSGVSSPVERAQSVDLEVDGDETDDEDFVVVAQNQRALKRFDLSKDFASTKTPPSSNSVDFKRQHQQLQQQQPQQQQLQHGRNGGVNKMPRMNLKSSLSTLSLVTSSPTREYALELERSRSPLTSCPILERNRIWNNGVTAVEQTSGPSSPTTNFSTIATAAAAAAAGGPALPSTETKDLNMDELECASVLAGLGWGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTT5</accession>
    <name>A0A9P6MTT5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Tetrahydrofolate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">ADE3_2</name>
        <name evidence="16" type="ORF">BGZ80_011150</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the C-terminal section; belongs to the formate--tetrahydrofolate ligase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000862">
        <property type="protein sequence ID" value="KAG0013329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTT5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004329">
        <property type="term" value="F:formate-tetrahydrofolate ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004477">
        <property type="term" value="F:methenyltetrahydrofolate cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004488">
        <property type="term" value="F:methylenetetrahydrofolate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00477">
        <property type="entry name" value="FTHFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01080">
        <property type="entry name" value="NAD_bind_m-THF_DH_Cyclohyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000006">
        <property type="entry name" value="Bifunctional protein FolD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000245">
        <property type="entry name" value="C-1-tetrahydrofolate synthase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10860:FF:000005">
        <property type="entry name" value="C-1-tetrahydrofolate synthase, cytoplasmic, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:005626">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.410.10:FF:000001">
        <property type="entry name" value="Putative formate--tetrahydrofolate ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.410.10">
        <property type="entry name" value="Formyltetrahydrofolate synthetase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10860">
        <property type="entry name" value="Leucine Dehydrogenase, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01543">
        <property type="entry name" value="FTHFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01576">
        <property type="entry name" value="THF_DHG_CYH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000559">
        <property type="entry name" value="Formate_THF_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020628">
        <property type="entry name" value="Formate_THF_ligase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000672">
        <property type="entry name" value="THF_DH/CycHdrlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020630">
        <property type="entry name" value="THF_DH/CycHdrlase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020867">
        <property type="entry name" value="THF_DH/CycHdrlase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020631">
        <property type="entry name" value="THF_DH/CycHdrlase_NAD-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48099:SF5">
        <property type="entry name" value="C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48099">
        <property type="entry name" value="C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01268">
        <property type="entry name" value="FTHFS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00763">
        <property type="entry name" value="THF_DHG_CYH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02882">
        <property type="entry name" value="THF_DHG_CYH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00085">
        <property type="entry name" value="THFDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00721">
        <property type="entry name" value="FTHFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00766">
        <property type="entry name" value="THF_DHG_CYH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00767">
        <property type="entry name" value="THF_DHG_CYH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0436">Ligase</keyword>
    <keyword evidence="12" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="10" id="KW-0521">NADP</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic" evidence="14">
        <location>
            <begin position="110"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding" evidence="15">
        <location>
            <begin position="247"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="35"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="47"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0013329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1011" mass="108939" checksum="EC79AE1FB5A26EF7" modified="2023-09-13" version="1">MIRITRKPAGSHTHRGFKSLAVAYQSRPLDGLGGITGRGVLGKDSSKSTSSTLGEESGLLSDQILNHPRHPSGYKKALTLEEAMGDIKPLELSPELTLMKETEPQGAKIIDGKAIAKAIVKNVKTEIEQFKLQNPTFQPRLAIVQLGEKEDSNVYVAMKKKICKQAGIEYTEHHMSESTSLEELLSTISYLNADPSMHGILVQLPLPAHIDAKIVTEAIDPIKDVDGFHTTNIGRLAKLSTMPDFVPCTPKGVLELIRSTGVEIEGKTAVVVGRSDVVGAPTFHLLNKNNATVTLCHDKTKNLAETVKTADILVVAAGHAELIKGDWLKKGAVVIDVGINAQKDSTKKSGVRLVGDVEFSKAKEVAGHITAVPGGVGPMTVAMLMENTLLSARRFWQAQTESRSLTKITPIPLALKEPVPSDIDIALAQTPKVIRQVAEEIGLGPDEFELYGKYKAKVDPDVLKRLEHRENGRYVVVTGITPTPLGEGKSTTVVGLVQALGAHLDKIAFGCVRQPSQGPTFGIKGGAAGGGYSQIIPMDEFNLHLTGDIHAVTAANNLLAAAIDARMFHESGATDTMLFNRLCPKKKGKRVFAPVMRQRLERLGIHRSEPEELTPEEISKFVRLDIDPDTITWQRVMDTNDRFLRKIEVGRNATEDGHARLTGFDIAVASEVMAVLALSADLKDMRQRLGKMVVASSRSGQPVTADDIGIGGALTVLMKDAIKPNLMQTLEGTPVFVHAGPFANIAHGNSSVIADRIALKLAGVEKGMDPSNMVATVKALKMHGGGPEVVPGKPLPEVYLNENLEMLEAGCANLVKHIQNAKKFGVPVVVAINKFTSDTDAEMALIRKLALEAGASDAVPCDNWAKGGLGAVELGKAVVEACDKPSDFKYLYDINDSIESKIETIAREMYGADGIELSQEAKDKISTYTRQGFAGLPICMAKTHLSLSHDPTKKGVPTGFRLPIRDIRASVGAGFLYPLIGNMQTMPGLPTRPAFYDIDIDFETGRVVGLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MU38</accession>
    <name>A0A9P6MU38_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_010868</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000804">
        <property type="protein sequence ID" value="KAG0013763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MU38"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0013763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="88" mass="10048" checksum="642CA75854FF0A3A" modified="2023-09-13" version="1">MVYAITIENLFCLKKVYIFIIANFIFINLYDASASASAAKTPLTFHEEMTKVRFSFNWWKEWTIIMGVFAVTGSSTVMVVKPVLKEGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUB1</accession>
    <name>A0A9P6MUB1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">CWH43-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_011530</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PGAP2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000938">
        <property type="protein sequence ID" value="KAG0012758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUB1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019402">
        <property type="entry name" value="CWH43_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039545">
        <property type="entry name" value="PGAP2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12892">
        <property type="entry name" value="FGF RECEPTOR ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12892:SF11">
        <property type="entry name" value="POST-GPI ATTACHMENT TO PROTEINS FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10277">
        <property type="entry name" value="Frag1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="3" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="132"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="CWH43-like N-terminal" evidence="9">
        <location>
            <begin position="13"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF10277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0012758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="267" mass="29538" checksum="50B7B28E66F1EBAF" modified="2023-09-13" version="1">MVYSTDKKAAVLSREWFPSVSATTGDWYPERNICQILIALASGPRLLLCYLWYLLILRNVPTNGSPGFAKLLLMNDVIRTIACGGWVYVTSSDDHAIHDFSMIIYLLCTVPHVVGTIKSAPQNLRTQKYRRICGYTFFGALVPMVYFFIQHNVHRVPGAYTYYAFFEWSLIISDLAFDAICMIDFETFELRVVDIGASGNHEGGAASNDFKTFGGGIRSRNLSGEGKAYSGEGGIFVGGKTNSILNELKPADALSFAADIYLGMTED</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MV56</accession>
    <name>A0A9P6MV56_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8">cAMP-dependent protein kinase regulatory subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BGZ80_011070</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="8">Tetramer, composed of 2 regulatory (R) and 2 catalytic (C) subunits. In the presence of cAMP it dissociates into 2 active monomeric C subunits and an R dimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the cAMP-dependent kinase regulatory chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000845">
        <property type="protein sequence ID" value="KAG0013444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MV56"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005952">
        <property type="term" value="C:cAMP-dependent protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030552">
        <property type="term" value="F:cAMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004862">
        <property type="term" value="F:cAMP-dependent protein kinase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034236">
        <property type="term" value="F:protein kinase A catalytic subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033554">
        <property type="term" value="P:cellular response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd12098">
        <property type="entry name" value="DD_R_ScPKA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.10:FF:000039">
        <property type="entry name" value="cAMP-dependent protein kinase regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.10:FF:000006">
        <property type="entry name" value="cAMP-dependent protein kinase type I-alpha regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.890.10">
        <property type="entry name" value="cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050503">
        <property type="entry name" value="cAMP-dep_PK_reg_su-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012198">
        <property type="entry name" value="cAMP_dep_PK_reg_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003117">
        <property type="entry name" value="cAMP_dep_PK_reg_su_I/II_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018488">
        <property type="entry name" value="cNMP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11635">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE REGULATORY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11635:SF152">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE TYPE I REGULATORY SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02197">
        <property type="entry name" value="RIIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000548">
        <property type="entry name" value="PK_regulatory"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00103">
        <property type="entry name" value="CAMPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00394">
        <property type="entry name" value="RIIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47391">
        <property type="entry name" value="Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00888">
        <property type="entry name" value="CNMP_BINDING_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00889">
        <property type="entry name" value="CNMP_BINDING_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0114">cAMP</keyword>
    <keyword evidence="4 8 9" id="KW-0116">cAMP-binding</keyword>
    <keyword evidence="6 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="11">
        <location>
            <begin position="176"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="11">
        <location>
            <begin position="299"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="70"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="106"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>3',5'-cyclic AMP</name>
            <dbReference type="ChEBI" id="CHEBI:58165"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="255"/>
        </location>
        <ligand>
            <name>3',5'-cyclic AMP</name>
            <dbReference type="ChEBI" id="CHEBI:58165"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="369"/>
        </location>
        <ligand>
            <name>3',5'-cyclic AMP</name>
            <dbReference type="ChEBI" id="CHEBI:58165"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="378"/>
        </location>
        <ligand>
            <name>3',5'-cyclic AMP</name>
            <dbReference type="ChEBI" id="CHEBI:58165"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR000548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000548-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0013444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="451" mass="50180" checksum="C60630355621ECDF" modified="2023-09-13" version="1">MFASSASSPSPMHRSLPQAYAEILNELNQKVIAAQPQDVLQFCANFFNQKLEEQRIRFLASARTVPQQNREVPQFLPVPPALSAPSPKIGSAATPAASSPDHSMESESESESDDDDDDQEEPSPLLTMPPNYMRGRRTSVSAESMVPSHQNYVKTVVPKTDEQRRRIEISISNNFLFKNLDEDQHEDVVNAMTEKRFQRGVNVIEQGAVGDFFYVVETGTLDVFVAKNGNPAEKVFEYGPGGSFGELALMYNGPRAATVTATSDVVLWALDRITFRRILMENTSRKRRMYEEFLETVPLLMSLEPYERHKIADALESVYFDDGQVVVKQGAQGDSFFIIESGEVTVTKCNDEGVEYAMPGLGPGQYFGELALLNDMPRAATVRAKGRLKCATLGKKAFVRLLGPVVEIIKRNSDNYQTIEQQIQQQKLLQEQQAAAEAALDATPPHPQEQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVC5</accession>
    <name>A0A9P6MVC5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_010431</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000725">
        <property type="protein sequence ID" value="KAG0014448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVC5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050266">
        <property type="entry name" value="AB_hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798:SF33">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G14860)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798">
        <property type="entry name" value="MONOACYLGLYCEROL LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="77"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0014448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="460" mass="52090" checksum="5AB473B3589EB8BB" modified="2023-09-13" version="1">MPSHAITRPTPGVMLSTAVALYLSYKVFRLIDAQRRRSAIEPSPTSPVLVDNFQFVQVNGKKLRVVHIPHALGSKVPLLVFIHGVGGQLEQFEKQIEYFSLSTHILAIDLCGYGGSDVPESFDHYTTDAYVEDIVILLQRYKSEDTVLICHSYGCAVGTHLYSRLESDSENTIKAMVMIGPKAAMTQHEVEGRVKLSKTPDWAIDFVRKFDRLGGAHSQSVNRLLHASAEDDLRRKQLKWNRASKTTVLRRLLMGARIPTPDEFRKIQCPLLLMVGEDDRVCPSVNVEQIYKWCRSANERTKSPFIIPKAGHQTMLEKWEHVTPIISSFLIKDCEMTTMDPAWQITKKCQEENKWSLKNTEKVGFIVDISKDEPPYRTSDFEATSITYTKLPTVSKIPPSKEDVERFIAHCNACWAQKPGVEIAVHCHYGIKDTRLLKLYVTLKALDHHAVSGMFIILQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVE9</accession>
    <name>A0A9P6MVE9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Plasma membrane ATPase</fullName>
            <ecNumber evidence="13">7.1.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BGZ80_010551</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The plasma membrane ATPase of plants and fungi is a hydrogen ion pump. The proton gradient it generates drives the active transport of nutrients by H(+)-symport. The resulting external acidification and/or internal alkinization may mediate growth responses.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>ATP + H2O + H(+)(in) = ADP + phosphate + 2 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:20852"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cell membrane</location>
            <topology evidence="13">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.1" evidence="13"/>
    <dbReference type="EMBL" id="JAAAID010000745">
        <property type="protein sequence ID" value="KAG0014264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVE9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008553">
        <property type="term" value="F:P-type proton-exporting transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120029">
        <property type="term" value="P:proton export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02076">
        <property type="entry name" value="P-type_ATPase_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000042">
        <property type="entry name" value="Plasma membrane ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000211">
        <property type="entry name" value="Plasma membrane ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006534">
        <property type="entry name" value="P-type_ATPase_IIIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01647">
        <property type="entry name" value="ATPase-IIIA_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42861">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="13" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 13" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="13" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="88"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="116"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="274"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="305"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="671"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="699"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="734"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="769"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="800"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="827"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="15">
        <location>
            <begin position="38"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="9"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU362083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0014264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="909" mass="99368" checksum="B11EAB0306DBAE65" modified="2023-09-13" version="1">MSDKAEIQSHGSSPSTSLHGEKAGGKIGNVEIEEQVHHEHVEEIPPELEALLHTDPLKGLTDDEVNQRRETFGRNELVEKKRHPLLKFLSYFTGAIAYLIEIAVICAAIVGDWADFGIILALLFVNAIIGFVEESKAESALDALKQTLALKTRCWRNGHLVELDTSELVPGDVIVLRLGDIIPADGRLLGIGATGEATEGDLQVDQSALTGESLPLAKNKGATVYSSSIVKQGQQMAVVTKTGGNTFIGRAAGLMAVATEEGHFQKIINRIGNFLILITVVLVLIILVFLLVVNRGTPKGAFKHVLEQVLVLTIAAIPVGLPTVMSVTMAMGAKELARRKVIVKRLTAVEEMASVSILCSDKTGTLTLNELTFDEPYLTNNYTSEDILLYSYLAAEPGANDPIEFAVRTAAEEQLEILKNRTHKHEIPGFKVTSFLPFNPSTKMTQATVMNTNTGESFKVAKGAPQVIIRLVGGDDDAARAVNSLAKRGLRALGVACTKPGSMEEYELVGMISLIDPPRPDSAETIRRCNEMGVDVKMITGDQQIIAKEVAHRLGMGRVILDAGHLVDPNKSDEDITEHCIRADGFAQVIPEHKYRVVELLQNRGILVGMTGDGVNDAPALKKANVGIAVHGCTDAARSAADIVLLAPGLSTIVDGLMTSRAIFQRMRSYALYRITSTIHFLMFFFCITLAMQWTMKPILLILICILNDGATLVISVDNAKISAHPDKWRIGQLIFLSVVLGALLTALSFAHFFIASNIFNVSPDQLEAIMYLHISSAPHFVIFSTRLSGYFWENMPSPIFFIAIMGAQVFAMLICIYGVIVGEAIGWAWGIAVIGVSLVYFIFLDFVKVFIFNQWSFEFTAHAWPTKIRKEKLAARKARAIQQKRVWTSIDKVRQVGLKIKVLEALKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MW53</accession>
    <name>A0A9P6MW53_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Conserved oligomeric Golgi complex subunit 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">COG5</name>
        <name evidence="7" type="ORF">BGZ80_010389</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000718">
        <property type="protein sequence ID" value="KAG0014523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MW53"/>
    <dbReference type="OrthoDB" id="18786at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017119">
        <property type="term" value="C:Golgi transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019465">
        <property type="entry name" value="Cog5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048485">
        <property type="entry name" value="COG5_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049176">
        <property type="entry name" value="COG5_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13228">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13228:SF3">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20649">
        <property type="entry name" value="COG5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10392">
        <property type="entry name" value="COG5_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Conserved oligomeric Golgi complex subunit 5 N-terminal" evidence="5">
        <location>
            <begin position="15"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="Conserved oligomeric Golgi complex subunit 5 helical" evidence="6">
        <location>
            <begin position="172"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF10392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF20649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0014523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="431" mass="48458" checksum="F3CADB29A2FF88F1" modified="2023-09-13" version="1">MTTIPELDSYTDYDSFLVDQFDPNTHANSIIHQSAKGELDIATSLSSLSFSIDSLNKQLHEQVTTHYNDLLSQAAGIRELETVLETVKLGLKALSTSMERLSFKIKTPFEQIQTYTIQLERLQIASEMLRRVLRFLYLSKRLEMQMPGGDLELTKAALTLSEVDALLQESDLEGIHVVDKEVRNLESVRGRIVHSADRMLQEGMDSQNQAQVGSALQVFYSLKRLDLKIVAMTSLISNKLHSQIKQAVDIQSLQKEAKESGASSSSGFVGGGVRRNNGEPSVGAAAVWTSILWKRMEKLMDEMYNGCVKIYLLERVLARKRDPLTQISFLEIASNNTDGNMVHRFWQSLSIHLEQELKASARSSQFLHQAFVDGFPRLLNLLHEFFSRVSVHSANTSSDDVQSPEVVLMLRAISSFEAAYKTKTAQRSNQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWW3</accession>
    <name>A0A9P6MWW3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">30S ribosomal protein S17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_009655</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000598">
        <property type="protein sequence ID" value="KAG0015749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWW3"/>
    <dbReference type="OrthoDB" id="274752at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00364">
        <property type="entry name" value="Ribosomal_uS17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000266">
        <property type="entry name" value="Ribosomal_uS17"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004123">
        <property type="entry name" value="PRK05610.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10744">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S11 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10744:SF1">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US17M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00366">
        <property type="entry name" value="Ribosomal_S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00973">
        <property type="entry name" value="RIBOSOMALS17"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0015749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="86" mass="9797" checksum="4D25DD1CA8DE7BEE" modified="2023-09-13" version="1">MRQNFIGVVVGTAMQKTVKVRVMSQKLHPVVRKTYKSFKNYLVHDEASKCKLGDVVRIEACRPISARKHFTVAEIVAASKVWEHSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWY7</accession>
    <name>A0A9P6MWY7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Integrator complex subunit 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">INTS2_1</name>
        <name evidence="2" type="ORF">BGZ80_008755</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000486">
        <property type="protein sequence ID" value="KAG0016944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWY7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032039">
        <property type="term" value="C:integrator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034472">
        <property type="term" value="P:snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029321">
        <property type="entry name" value="INTS2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28608">
        <property type="entry name" value="INTEGRATOR COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28608:SF1">
        <property type="entry name" value="INTEGRATOR COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14750">
        <property type="entry name" value="INTS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0016944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="307" mass="34172" checksum="C21ABADAC05B2FC2" modified="2023-09-13" version="1">MIFRLFVQILGAVMVGSRHWFRKQFHASQAIPLAPQNRNPTQVQRRQFKEVNLSTMLYIQDSTLIQLMLEACEARPEDLTLSTKPIKHGKNIKQGKPAKGDKGDKGDKGDKGDRGDRGDKGPQMEISEALQEVRVVTFNFLHQLFIDHKIFPKLVHFQGYAMDLLPATVAGIDSIHVCLDFLQELLFANAPASMLASSSIVSSTGTGLGSGGSGEVRIDQAPQVFALRLAAHLCERFPLRNTLQMAEEVILPRLQALAISTGFSKVVLESAVILAKAFPSLRNEIFRILREKEEEEELTCTSRVLCY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MX91</accession>
    <name>A0A9P6MX91_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">t-SNARE coiled-coil homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_008693</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the syntaxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000480">
        <property type="protein sequence ID" value="KAG0017010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MX91"/>
    <dbReference type="OrthoDB" id="10251371at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048278">
        <property type="term" value="P:vesicle docking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006906">
        <property type="term" value="P:vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15845">
        <property type="entry name" value="SNARE_syntaxin16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010989">
        <property type="entry name" value="SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045242">
        <property type="entry name" value="Syntaxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006011">
        <property type="entry name" value="Syntaxin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957:SF83">
        <property type="entry name" value="SYNTAXIN-16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00503">
        <property type="entry name" value="SynN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="10">
        <location>
            <begin position="221"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0017010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="303" mass="34817" checksum="A5349EB75A71A925" modified="2023-09-13" version="1">MATRSRTLLFLQFRNSYSGSHAATIRQQYNQQQQQHQQSSLLATADDNERVGLMDGAETTIELMMLPPKWVDIVDEVDEELNKIKANIQKLDGMHKKHLLPGFDDRIQEERDIERLTDEITQQFHASQRRIKRINSESRHSSSSQELAMAKNVQMSLAQKVQDASTIFRQKQNTYMQRMRGVELRSKDIFSGVQPINSSLSDDPEESGFTSAQLAFAEQSNATITQREQEINHISSSIMQLADIFRDLQTMIIDQGTLLDRIDYNVEQTAVHLQDAVYELDEVQENAHKTLNYFSACGYRMNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MX93</accession>
    <name>A0A9P6MX93_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Methyltransferase type 11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_008426</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000456">
        <property type="protein sequence ID" value="KAG0017302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MX93"/>
    <dbReference type="OrthoDB" id="10027013at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051052">
        <property type="entry name" value="Diverse_substrate_MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44942">
        <property type="entry name" value="METHYLTRANSF_11 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44942:SF4">
        <property type="entry name" value="METHYLTRANSFERASE TYPE 11 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="4">
        <location>
            <begin position="44"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0017302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="268" mass="30272" checksum="0155F11DA1CF54E7" modified="2023-09-13" version="1">MATFSNKTFNSALYQSFRPGYNANFYKMVYSYHAKKNGQFDTAVDVGTGTGQVASALAEKFKQVHGIDASATMLASAVKKPNITYHISKGEDLSVIPNASVDLLTVAQAMHWFDTPTFFSEVKRVLKPHGTFAAVGYTFVEFDKYPRASKHIKDLGNEPELLGTYWEPGRLILDNMYKCIHVPMEGVERYYLPNEELPALMSEKVTMQHFRNYIKTWSAYKNYCDKHVGEPDIVDKTIDTIMAEENLKDEDVVEITLPTVLILAENKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXF1</accession>
    <name>A0A9P6MXF1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">sphingomyelin phosphodiesterase</fullName>
            <ecNumber evidence="2">3.1.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_009311</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the neutral sphingomyelinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.12" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010000544">
        <property type="protein sequence ID" value="KAG0016309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXF1"/>
    <dbReference type="OrthoDB" id="40902at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004767">
        <property type="term" value="F:sphingomyelin phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd09078">
        <property type="entry name" value="nSMase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038772">
        <property type="entry name" value="Sph/SMPD2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017766">
        <property type="entry name" value="Sphingomyelinase/PLipase_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03395">
        <property type="entry name" value="sphingomy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16320:SF23">
        <property type="entry name" value="SPHINGOMYELINASE C 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16320">
        <property type="entry name" value="SPHINGOMYELINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="5">
        <location>
            <begin position="39"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0016309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="305" mass="34686" checksum="E7E7F807EBEAA2DF" modified="2023-09-13" version="1">MSSSTTTATLRILSHNILFLPEWRQSLGQSKRARLMARADYLRGHDVVFFQEAWDPNATKIVREALQEQYPFQTPVAGHSYGGWNATSGSFSRLTAANAGVFIASKWPIVFQQQHVFRNASGGERLKNRGFVYAKILYNNSKHIHLINTHLQTDGAFMSDFAECAQMRVLQLQEIRDFIASSGIPHEEPVIIGGDLNVVKASWEYGALVKENLVVMEPTQSLGHPYSWDCHRNSFIAHYSWAGCMVLDYLLVAKAHSSRVRSFVVETMLVQPRESFQVSKWFKKSWTVRDYSDHYPIKATITVDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXQ3</accession>
    <name>A0A9P6MXQ3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 11">Alkaline phosphatase</fullName>
            <ecNumber evidence="2 11">3.1.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BGZ80_008203</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a phosphate monoester + H2O = an alcohol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:15017"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:67140"/>
            <dbReference type="EC" id="3.1.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="9">Binds 1 Mg(2+) ion.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 2 Zn(2+) ions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the alkaline phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.1" evidence="2 11"/>
    <dbReference type="EMBL" id="JAAAID010000438">
        <property type="protein sequence ID" value="KAG0017518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXQ3"/>
    <dbReference type="OrthoDB" id="7392499at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004035">
        <property type="term" value="F:alkaline phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16012">
        <property type="entry name" value="ALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.60.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001952">
        <property type="entry name" value="Alkaline_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018299">
        <property type="entry name" value="Alkaline_phosphatase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11596">
        <property type="entry name" value="ALKALINE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11596:SF5">
        <property type="entry name" value="ALKALINE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00245">
        <property type="entry name" value="Alk_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00113">
        <property type="entry name" value="ALKPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00098">
        <property type="entry name" value="alkPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00123">
        <property type="entry name" value="ALKALINE_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 9 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9 11" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Phosphoserine intermediate" evidence="8">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="5"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="5"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="263"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="301"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="302"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="409"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601952-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR601952-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0017518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="487" mass="53763" checksum="A68C3167989961F8" modified="2023-09-13" version="1">MMVSDGFGPASQTYARSYYQYVHSNPKSPKKEYVSPLDKILVGSSRTKSNSSLITDSAAGATAFSCSLKTYNGAVGVDPTGTPCGTILEAAKALGMLTGMVVTSRITDATPASFSSHVPHREMESEIAEQQIGDYVLGRQVDLMMGGGRCFFLPNTTKGSCRKDDRDLIKESQDNFDWKHVMLNRQEFLALDEEDEGIPLPAMGLFNQGHLSFEVDRDKSARGSEPSLKEMTKAALKSLKGNAGPNQGFFLLIEGSRIDLAAHNNDPVAHVHEILQYHEAVAVVRAFVANNPDTLLISTSDHETGGFTLGFQDDPNVYPEYIWKPEVIQAANASTEVLADKLVSYTGRGRDRRQFVRTVILDRGLGIKDPTDEELTFLADPASSHQDILIFLGRAISRRAYLGWTTIGHTGVDVNLYAEGDNVAVNELRGNHENTEIGAAMSKFLNVDLDYITRRLEKDVDRWFKPMNSFWRNQFGGRSSKHEMTGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYD8</accession>
    <name>A0A9P6MYD8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">26S proteasome non-ATPase regulatory subunit 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">PSMD12</name>
        <name evidence="4" type="ORF">BGZ80_008415</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the proteasome subunit p55 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000455">
        <property type="protein sequence ID" value="KAG0017310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYD8"/>
    <dbReference type="OrthoDB" id="268763at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008541">
        <property type="term" value="C:proteasome regulatory particle, lid subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000070">
        <property type="entry name" value="26S proteasome non-ATPase regulatory subunit 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054559">
        <property type="entry name" value="PSMD12-CSN4-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040134">
        <property type="entry name" value="PSMD12/CSN4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040896">
        <property type="entry name" value="RPN5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10855:SF1">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10855">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12/COP9 SIGNALOSOME COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22241">
        <property type="entry name" value="PSMD12-CSN4_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18098">
        <property type="entry name" value="RPN5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0647">Proteasome</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="3">
        <location>
            <begin position="234"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0017310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="445" mass="51477" checksum="139F5D5D17D1085A" modified="2023-09-13" version="1">MDEPIQKMEKDCSAIVDAQFPEIEASAKGGNLTKALEQLLSLEKQTRSSADLASSTRVLKRFIQLTFEANDWKLMQEYIVLLSKKHGQLKQAITKMIQESMECLDKTPDMKTKLELIDTLRTVTDGKVYLEVERARVTRILAKIKEDEGNVTEAADIMQDLQVETFGSMEKREKTDFILEQMRLCLLKRDYVRANIISKKINIRYFKDTDVQDLKLRYYDLMIEYSLHENEYLSVCKHYRQIYDTPVIKEDPAKAKKAVENAVLFVILAPFDNEQSDLIQRVYLEADEVDTTVYRDLLKCFITAELMRWPMIEQIYGPTLGQNPALAGGDEASKKRLKELHNRVVEHNIRVIAKYYTRITTKRLTQLLDLPDKDCEEFLSKLVVSKTIYARIDRPSGIVSFAKSKHPNEVLNEWSQDINGLLSLIEKTCHLITKEEIIHSITKVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZ09</accession>
    <name>A0A9P6MZ09_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008039</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000424">
        <property type="protein sequence ID" value="KAG0017680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZ09"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0017680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="71" mass="7570" checksum="EF132183D5824D2B" modified="2023-09-13" version="1" fragment="single">MPARGFATSPSSPGHSTNPTSSYYYPATQGSTNPLLGNQDNLCILTNGDVVLFSAFDWIDSGNNSKNKTSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZ42</accession>
    <name>A0A9P6MZ42_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RlpA-like protein double-psi beta-barrel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_006536</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000323">
        <property type="protein sequence ID" value="KAG0018936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZ42"/>
    <dbReference type="OrthoDB" id="623670at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22191">
        <property type="entry name" value="DPBB_RlpA_EXP_N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051477">
        <property type="entry name" value="Expansin_CellWall"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009009">
        <property type="entry name" value="RlpA-like_DPBB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836:SF28">
        <property type="entry name" value="SRCR DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03330">
        <property type="entry name" value="DPBB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="Barwin-like endoglucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040357364" description="RlpA-like protein double-psi beta-barrel domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="RlpA-like protein double-psi beta-barrel" evidence="3">
        <location>
            <begin position="55"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0018936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="149" mass="15882" checksum="4CD1391F863AC3CE" modified="2023-09-13" version="1">MNTFYKFAILATTALAVVAAPIESSATRNTTATLIPLSQQGAKVLSTTISDSEFSGRGTWFTDTVGSCETPFDTNDMIVAVNAEQMDGTSQCGRTVKITVDGKSVEATVVDTCPSQYCSYGALDLSQAVFKKFAPLSQGVIQVTWKFVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZL2</accession>
    <name>A0A9P6MZL2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006817</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000339">
        <property type="protein sequence ID" value="KAG0018731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZL2"/>
    <dbReference type="OrthoDB" id="10257049at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08241">
        <property type="entry name" value="QOR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002364">
        <property type="entry name" value="Quin_OxRdtase/zeta-crystal_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051397">
        <property type="entry name" value="Zn-ADH-like_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43677:SF4">
        <property type="entry name" value="QUINONE OXIDOREDUCTASE-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43677">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01162">
        <property type="entry name" value="QOR_ZETA_CRYSTAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="1">
        <location>
            <begin position="11"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0018731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="334" mass="35752" checksum="40266144C0CE66B5" modified="2023-09-13" version="1">MKAILIEKALTSVDQMTVHTVADPVPKKGQVLIEVKAAGLNFFDILQVQEKYQIKPPYPYVPGAEFAGVITQIHPETKTTFKIGDRVFGSTQGTYAEKLVCEPKSLLAVPDNLSFEQASGLFVTYPTSYAALKDRAGLKKGEWCLIHAAAGGVGLCAVQIAKALGAKVIATASSQSKLDIALKNGADYGVNYREKDWAAQVLKITEGKGVDVVYDPVGLINESLRCVAWSGRILVVGFAAGTIEKIAANRILLKNVSIVGVFWGSYGKYDVGTVARVWKELLVLFAEGKLVPVVYEKLYQGLDSVKTGLNDLAARKTFGKAVVVIGGAGATSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZV3</accession>
    <name>A0A9P6MZV3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_006641</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000329">
        <property type="protein sequence ID" value="KAG0018847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZV3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047574">
        <property type="entry name" value="AD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039683">
        <property type="entry name" value="Lsm12-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019181">
        <property type="entry name" value="LSM12_ABD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13542">
        <property type="entry name" value="LSM12 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09793">
        <property type="entry name" value="AD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52001">
        <property type="entry name" value="AD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AD" evidence="2">
        <location>
            <begin position="218"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="64"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS52001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0018847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="263" mass="27093" checksum="FBAE017B2D0CABB7" modified="2023-09-13" version="1">MESLNKKTPISFAAAAGKISLAQPASASPPPTTTTTTASTSTGGTTSGSGQPPTKNGANVPGNQSSSSQGSQSLSSSVPTSGTGAIKSTASASSGSIDWIVGLNVKVITQADDVFEGQVYAYDVIMNCICQSKITSTATTPATYYSQSLGGNCSAPRPKYDFRILKINYIKEVVPLSTTAASNVKETELSEEGKTNAGANNSNSITSNVYSTALPVVGYVQLDKIQQREQQAVREVQAAAARIGVGVTSIAQDIFDALSKTYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZW8</accession>
    <name>A0A9P6MZW8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">O-acyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BGZ80_004752</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Sterol O-acyltransferase that catalyzes the formation of stery esters.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000239">
        <property type="protein sequence ID" value="KAG0020116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZW8"/>
    <dbReference type="OrthoDB" id="10039049at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034737">
        <property type="term" value="F:ergosterol O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008204">
        <property type="term" value="P:ergosterol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004299">
        <property type="entry name" value="MBOAT_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014371">
        <property type="entry name" value="Oat_ACAT_DAG_ARE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10408">
        <property type="entry name" value="STEROL O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10408:SF9">
        <property type="entry name" value="STEROL O-ACYLTRANSFERASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03062">
        <property type="entry name" value="MBOAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="257"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="295"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="327"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="356"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="503"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="540"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="675"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="150"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="404"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="158"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="185"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0020116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="697" mass="78364" checksum="57B896857FD1960D" modified="2023-09-13" version="1">MVEAKPTQLHFEPLEHPKSASKIIDSDMYSNMGRRPARPLDDSEEEGGSSLGAQVVPDYDVAMDMMSSQKDQESIFQEDTTTTTTTTITTARIHKRVSLKDGLEGLVAHHQDVHTRHQQQALAPSDESLSQITTEKASLLLEQGQNMAIRSPTESKAKQSLSVSTSSTSASAALQKQLDHHHNTLSDSSNSSSVESTESSPGPDTPTSVDAYNTISITSIATKKKRRVRLPTFEARPSALDPETLSKTLNPFRGFHNLFWLIMGAYGILTFDAEWTRVGKVFGGSLFSSFSQDAIMLAISDFFLVSATAIAFLLIKAISKGWLRYRVAGMVVQHSVQALFLLSAIIWTLWRQWPWVQSGFFTLHAITMLMKIHSYIAFNGELSEKLIQLKTYEATYAEIKGSDACTADSNSSSRDTRDTSGLHHRLTSQTETAPLQGSVPNAAAIDASLLASEIDELKNDLRCESGELWPANVTVANFFDYLIIPTLIYELQYPRTSRIRPKYVFEKVVATFGTFTLLYLTTEHYIYPVVFDPTISPLKALKLLLIPFMMNYLLIFYIIFECICNAFAELSRFADRNFYDDWWNCTNLDEWARKWNKPVHNFLLRHVYFSSIESFHLSKANAAMATFFLSSCVHELVMMIVTGKVRMYLFVLQMGQLPIIWLGHRQVIRENPRLANVLFWAGMFSGPPLLGVAYCYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N029</accession>
    <name>A0A9P6N029_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_006674</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000330">
        <property type="protein sequence ID" value="KAG0018837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N029"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051615">
        <property type="entry name" value="Transcr_Regulatory_Elem"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313:SF81">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="24"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="94"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="169"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="475"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="628"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="753"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="856"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="110"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="139"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="173"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="202"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="221"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="634"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="753"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="861"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="882"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="895"/>
            <end position="916"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0018837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="923" mass="101560" checksum="B744428DBC2DF2C0" modified="2023-09-13" version="1">MTDPAPSTLGITLPPTSVLKIRDACLPCRKQRSKCDGQPCCARCAHLDLECTYVELVKAPAPTPKEPWQEFLSTTGAKPEALVIPPIELLKDTSSGPLLDASTFPWQRTKTSRRRKQTTRRCTCPVSPASDLADQDLNSPQTPSPSLSTSSAFEQNNSMTDATAVSNGDVNTAVSSDSAPATSSNSRRRGRSSTGPCRVHNPQASAEPTRSITPGSSSPGLLNNANSQSSGSSSSLRHRPLLSSEPIQLPSSVIETSEKINSLSSKLSRLYVFPDAHPLPAPPPQLEILQSRSLSPLLQSHLIQLYLAQCLPVQPIVDAPTFMAQLAAQEYCTPPHPLLIAAMCASAARCIDDADVERLWSEQDPPLPNPIYPNFANGEANVRSTRDMIWSIGEYFAALAKAYLRTELPLVQSPDRSGGMGDPLTVLHYHPFEAEDGTDYNHEVNAHDVQRLEARLHEIDNHLDEYLKRTPAEFRPDWGQAAGDEGDSTAGYEPTGSSQFFHAGGDWWWRHAMGGMVDMSYYALKLLLHRPQHVFSKVPTTLSPLTLAQYANRITLTCERLWQYPTTRPTFYHMAGAPLWLALCYQQENTLSDNPRIRTPACVNMQKSYFLLKKAGRLVHSNEDEPLTELEDTNGASPTPSTPSNVPFMRPTDEQRVKPMMAIFKEMFPIARQALRDKGFGLRTRPNATARFSSNMIIQNIQDAAIAGVPDPVDTVGSATAASISMSAASIMSTNSSPGPSTFYLAPLTPPGTSNASVASPMTESQGSAPSPSPPPALVPGSCGNTTAVNDASQIYMDPSLQHLHQLQQCQQYQQQPLFPTHQCSPLVGQVQYDRNQTASIHQHQHQHLQAYPSQQHLYNQQQQQQQQQQQQQQQQQSNQQYITQGMQSSPAIPQQQQQQQQQQQQQQQQQQSSQSVQLHRAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0B5</accession>
    <name>A0A9P6N0B5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribonuclease P protein subunit p29</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">POP4</name>
        <name evidence="10" type="ORF">BGZ80_006497</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of nuclear RNase P and RNase MRP ribonucleoproteins. RNase P consists of a catalytic RNA moiety and 10 different protein chains; POP1, POP4, POP5, POP7, RPP14, RPP21, RPP25, RPP30, RPP38 and RPP40. Within the RNase P complex, POP1, POP7 and RPP25 form the 'finger' subcomplex, POP5, RPP14, RPP40 and homodimeric RPP30 form the 'palm' subcomplex, and RPP21, POP4 and RPP38 form the 'wrist' subcomplex. All subunits of the RNase P complex interact with the catalytic RNA. Several subunits of RNase P are also part of the RNase MRP complex. RNase MRP consists of a catalytic RNA moiety and about 8 protein subunits; POP1, POP7, RPP25, RPP30, RPP38, RPP40 and possibly also POP4 and POP5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the eukaryotic/archaeal RNase P protein component 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000320">
        <property type="protein sequence ID" value="KAG0018977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0B5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000172">
        <property type="term" value="C:ribonuclease MRP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030677">
        <property type="term" value="C:ribonuclease P complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033204">
        <property type="term" value="F:ribonuclease P RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001682">
        <property type="term" value="P:tRNA 5'-leader removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.210:FF:000001">
        <property type="entry name" value="Ribonuclease P protein subunit p29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.210">
        <property type="entry name" value="Ribonuclease P/MRP, subunit p29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016848">
        <property type="entry name" value="RNase_P/MRP_Rpp29-subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036980">
        <property type="entry name" value="RNase_P/MRP_Rpp29_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023534">
        <property type="entry name" value="Rof/RNase_P-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002730">
        <property type="entry name" value="Rpp29/RNP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13348:SF0">
        <property type="entry name" value="RIBONUCLEASE P PROTEIN SUBUNIT P29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13348">
        <property type="entry name" value="RIBONUCLEASE P SUBUNIT P29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01868">
        <property type="entry name" value="RNase_P-MRP_p29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF027081">
        <property type="entry name" value="RNase_P/MRP_p29_subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00538">
        <property type="entry name" value="POP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101744">
        <property type="entry name" value="Rof/RNase P subunit-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="49"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00046486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0018977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="211" mass="23810" checksum="82D336375AFC0B36" modified="2023-09-13" version="1" fragment="single">ATASTSSLTGDTQSFVNKYVEDAVVEGFEADKVYSTKVKNKVFMLDNPAKDQTEAKEKQKSRRRANKSKALTAKEKRALNVYDIPIESRKYELFLPLHELWKGYMEELFRSTNPVAFTQKLLKADFHGALITVSRSKCPTYVGTSGIVAQETENVFKIITPSNALLVIPKVNNVFTLHIRGSVFTVHGNQFRYRAAQRSAKKFKSKPTIDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0T0</accession>
    <name>A0A9P6N0T0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005505</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000271">
        <property type="protein sequence ID" value="KAG0019634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0T0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="9"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0019634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="464" mass="52254" checksum="C15824307FB8E4AE" modified="2023-09-13" version="1">MNQIHVLDVPELLALICSYLKLHDYAACARVCRHWNSVFTALVWRDVSITNTLQDAAILSAEGQQGFTRNLPYVQSIQIRFVQTLDALLPFLRPKINNLTRFVIPASFEYRVPLYPKDYEVSVHDYHLQTIVRRISEREDFGVEPIGTDYHQPLPPEQVPIPEEKLPLAPDFEALKYLVDNLAPNLSYLGLSIYCSATVGLNSPWMADDIPDASSASSTETMASIVDSFPASDVIEGSGLSSSSVGISDVKPNKLKEILIDGDMRGFECGPGTSASQQHEETPQLALPPQGQSLDIQQNQVQEANPHHFFQAVVHQMQNFQNGQLAQPLRSNAATLQRQVYQRLATLTELEELWVGEPDFEQISVNHLLMIKRLQPTNVSITLENASNLEFSLNSGLEIMAGMKKLRVLGVRGLRHCIGIPELRWMVHEWPKLERIDGLLLSYNEETPEMEQWLKSNAPFLQYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0T4</accession>
    <name>A0A9P6N0T4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003734</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000200">
        <property type="protein sequence ID" value="KAG0020724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0T4"/>
    <dbReference type="OrthoDB" id="10456045at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0020724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="128" mass="13126" checksum="43BDF767E69FA6B0" modified="2023-09-13" version="1">MSQSMSTSPTLVPTATTSLLPIVDTTPALEGLHHRSFRINRRAIGGSRGGGSIGGSHGGIGSRPPSIHPEEPAPIIPYTGTSNPGRVYGGSSGTGGMSKNAATATKAQKKFSLFFIVLTILPTIINSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0W0</accession>
    <name>A0A9P6N0W0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005585</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000275">
        <property type="protein sequence ID" value="KAG0019587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0W0"/>
    <dbReference type="OrthoDB" id="250548at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019351">
        <property type="entry name" value="DUF2039"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22876:SF5">
        <property type="entry name" value="CHROMOSOME 9 OPEN READING FRAME 85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22876">
        <property type="entry name" value="ZGC:101016"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10217">
        <property type="entry name" value="DUF2039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0019587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="196" mass="22354" checksum="CACF229F539AB5F0" modified="2023-09-13" version="1">MSDKPYESKKVSSRKGNNKKGAQAHKNAYAFHANKSSKITKKIAAMPVGGLCEKCVEVIMWRKKFKKYKPLTTTKKCVNCEQKAVKDAYHVICNKCAGEKNVCAKCLESREIVPTNIKTEKEIIQEQVELERLLSGMTERERRSYLRQMERKKNTGEGEDGEDNSAEGSDNEDDSDEDSEDDDDDEEEEEESEDEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0W5</accession>
    <name>A0A9P6N0W5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Chitin synthase export chaperone</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">CHS7_1</name>
        <name evidence="13" type="ORF">BGZ80_005193</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CHS7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000258">
        <property type="protein sequence ID" value="KAG0019831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0W5"/>
    <dbReference type="OrthoDB" id="2189463at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022057">
        <property type="entry name" value="Chs7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35329">
        <property type="entry name" value="CHITIN SYNTHASE EXPORT CHAPERONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35329:SF2">
        <property type="entry name" value="CHITIN SYNTHASE EXPORT CHAPERONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12271">
        <property type="entry name" value="Chs7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="49"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="84"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="112"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="151"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="184"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="222"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="253"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0019831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="343" mass="37988" checksum="279B4BC8FC85C3EF" modified="2023-09-13" version="1">MSTYLDFKFGSFNNTCSKVSLTLCPLVGSTDGIEPLCYSRNVKLADTLIFQPSTLIIHIIALVMTAIMIYHIRSKYTAVGRKEIVMFFYLYMLVTVMDLLLISGIIPTASNLYPYFTGVHIGLISATFWCLLLNGFVGFQFAEDGTPLSLWSIRISSFVIFSAITFLSIATFESLGPFSATNPVTLWVVFFVFNGACLLIYVILQILLVVNTLDDRWPLGDIVFGVAFFSVGQVVLYVFSINICNFAKHYIDGLFFGTIATLLSVMMVYKYWDSITKEDLEFSVGSKQNVWEVKELMGDDEMAGGGYGQQQQHLGPPGSGFGYNGNSPAPGTYGQANFYDGAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N208</accession>
    <name>A0A9P6N208_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">26S proteasome non-ATPase regulatory subunit 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">PSMD5</name>
        <name evidence="1" type="ORF">BGZ80_000777</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000117">
        <property type="protein sequence ID" value="KAG0022206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N208"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043248">
        <property type="term" value="P:proteasome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019538">
        <property type="entry name" value="PSMD5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13554:SF10">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13554">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10508">
        <property type="entry name" value="Proteasom_PSMB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0647">Proteasome</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0022206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="414" mass="44992" checksum="1B7B47DDBA7A2641" modified="2023-09-13" version="1">MPSVQNTPTDNSSSPQLQDILSTFTSLTDPIAINDALLVIDRALQDPLMSGALLQSLNSPSPRIHALGLAQVDKISKEDISVLRSTLESDIFKTTVEGIASESISIAERSKQTLLKICSTEERLAAVIDFEGSVYLIQDLANSRNSVVRMRMIEALTELAGRSHESLDALQKTSLLDSLKDGLTSADILTRFNIIEILSEFGATEAGSEFLDQSGILTLIANVVENEADQDSLGVNAIAKLYGKLGASDKVDFISLDMKYQILAQLEKLMVGDDDFEPDELLKTESMASFGLVGGNVQNIEWVSQSHCAQVFIDLLTSLPRDLKVACHVGLGGDDTAGTLFVWRSDRNAEFTHAQKVAKYEVIEAILGTAEAVKKNSNIAILTTEQISRLDLVRRQGPFYRRATATVAVQDMAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N331</accession>
    <name>A0A9P6N331_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S25</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RPS25</name>
        <name evidence="6" type="ORF">BGZ80_009527</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS25 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000058">
        <property type="protein sequence ID" value="KAG0023403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N331"/>
    <dbReference type="OrthoDB" id="10263513at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.63.20:FF:000001">
        <property type="entry name" value="40S ribosomal protein S25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.63.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004977">
        <property type="entry name" value="Ribosomal_eS25"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12850">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03297">
        <property type="entry name" value="Ribosomal_S25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU366057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0023403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="118" mass="12851" checksum="370DD4E9F4AF8786" modified="2023-09-13" version="1">MAKKDVAAKPSSSSGGKAKKKKWSKGKVKDKANNAVILDKATYDKLMKEVPTYKLVSPSVLVDRLRVNGSLARTAIRELVKLGLIVPVSTHGAQWIYTRATGVEEEKKAKKAEAEADE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N366</accession>
    <name>A0A9P6N366_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein-serine/threonine kinase</fullName>
            <ecNumber evidence="8">2.7.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_009205</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the PDK/BCKDK protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.-" evidence="8"/>
    <dbReference type="EMBL" id="JAAAID010000053">
        <property type="protein sequence ID" value="KAG0023523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N366"/>
    <dbReference type="OrthoDB" id="3264224at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004740">
        <property type="term" value="F:pyruvate dehydrogenase (acetyl-transferring) kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010906">
        <property type="term" value="P:regulation of glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.20">
        <property type="entry name" value="Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036784">
        <property type="entry name" value="AK/P_DHK_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018955">
        <property type="entry name" value="BCDHK/PDK_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039028">
        <property type="entry name" value="BCKD/PDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11947:SF20">
        <property type="entry name" value="[3-METHYL-2-OXOBUTANOATE DEHYDROGENASE [LIPOAMIDE]] KINASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11947">
        <property type="entry name" value="PYRUVATE DEHYDROGENASE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10436">
        <property type="entry name" value="BCDHK_Adom3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69012">
        <property type="entry name" value="alpha-ketoacid dehydrogenase kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="7 8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase/HSP90-like ATPase" evidence="10">
        <location>
            <begin position="397"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="324"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="52"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0023523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="597" mass="65782" checksum="853E1E77FAFDA469" modified="2023-09-13" version="1">MQHSHTLSRLQSRSAPAAFVRHATHPNLGHSTSAVRKVHTTQRIKQNKAVDGSNSTGPLSPQNKFGANAIINTVPSCPKRSIWNQPSIYRNHLHPHPRTGVASVAAAAPHLLQATDVASLRASAATRGFNSQSEQREIDDVVSFYDDKLTQYANQDIQRVTLKTLLGLGRSGLSTPSSSSTSATQREQNATKDLAINLDVARYARKELPVRLARLIKSTQQLPFIVGTNPYIKQVYKLYYDSFQTITASPKELKNKEDLDRFAALLQGLVASHADVIPMLSQGFLECQKYMQKDDIKKFLDGVIRSRIGIRLIAEQVISLREQRTDSDVDDDNDKKKQSKSSSIPRPKDVVGVVHTELRPADLVKTCASFVQELCDINYGSSPEVVINGQTDTTFTYVPVHLEYILCELLKNSVRATVEYSQKIGRSALNASHLSAKKSTFSSADKRSNGVVIMNQDDDLDITKRPNEFGHPPVEVTIAQGDHEVTIRIRDHGGGISREHFDSIFDYSFTTVKNENDSDAGGDSPYGVDSIFKGVSRLAMQAGLGGPIAGLGFGLPLTRIYAQYFGGDMQLVSLQGYGCDVFLKLKQIDETLDDLQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N394</accession>
    <name>A0A9P6N394_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Fanconi-associated nuclease</fullName>
            <ecNumber evidence="8">3.1.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_000310</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Nuclease required for the repair of DNA interstrand cross-links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>Hydrolytically removes 5'-nucleotides successively from the 3'-hydroxy termini of 3'-hydroxy-terminated oligonucleotides.</text>
            <dbReference type="EC" id="3.1.4.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the FAN1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.1" evidence="8"/>
    <dbReference type="EMBL" id="JAAAID010000106">
        <property type="protein sequence ID" value="KAG0022416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N394"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008409">
        <property type="term" value="F:5'-3' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017108">
        <property type="term" value="F:5'-flap endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070336">
        <property type="term" value="F:flap-structured DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004528">
        <property type="term" value="F:phosphodiesterase I activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036297">
        <property type="term" value="P:interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22326">
        <property type="entry name" value="FAN1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033315">
        <property type="entry name" value="Fan1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049132">
        <property type="entry name" value="FAN1-like_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049125">
        <property type="entry name" value="FAN1-like_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014883">
        <property type="entry name" value="VRR_NUC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15749">
        <property type="entry name" value="FANCONI-ASSOCIATED NUCLEASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15749:SF4">
        <property type="entry name" value="FANCONI-ASSOCIATED NUCLEASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21315">
        <property type="entry name" value="FAN1_HTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08774">
        <property type="entry name" value="VRR_NUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00990">
        <property type="entry name" value="VRR_NUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 8" id="KW-0464">Manganese</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 8" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VRR-NUC" evidence="10">
        <location>
            <begin position="894"/>
            <end position="1009"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="130"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="469"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="493"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="818"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="28"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="44"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="130"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="143"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="472"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="501"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="821"/>
            <end position="831"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU365033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0022416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1024" mass="116820" checksum="8D33359B21A8B452" modified="2023-09-13" version="1">MKKRGATNTAAKGKGRKAASDEPSTPKTGDKRQLPLDFSRHAVVNSNAKKNSTIQENATKPSNTPQIEPSLVSGNTSFYSCVLEPQVIRVNLVAPRALGVSVGKDNGYPTDIGTAAATVLACHRPIYDENQELYDEEEDDDDSALRSEATKRSHSNEGIECEDEESLEAKIKIEDMLDLALPNVRIKHLEEDNKDPDMLLPTQFRWKTVYVAAFELALDTVLPEEALLFTDEEHSLFETYRALEDDPKHLFVRLFLRNQKYWQRQSKLEGRYQEIENLESAIQQLIIVGLLMDQRAIDDPEEALAMLTMDELKILARRIGIAEKLSGKQQSFLSKRLLLAPGGAANGGTDRKTGLATHMFSGDSSKRDNALLEKIVDISVFQRLHLVFNRTQEYTEKPILTSAILAKIGQRTFPSYEITRTNTVFRNRDELLKYEAAIKLHFDLSEMIESAMGPGRAATVYVRDGDQEVKSGANSSASRKPSTLKPSAKKYLETEGAGADSKADQEEKDPEQERRRLEVIGIYEKVIQEAENIRCAWREYIATETEMSKKSPSYFLLRFSPELRAFAFLKRFEEESILLHELLDQHIYSLGKRGGWYERLALIKSNYAFQKRLVDATLIQARIIRLESELKVSFRDRHDFSYLTLRKAQTRILTGERLNTPGTAAPSYASSHSYSYIPNSMGSSSHPIAQQRPLWRNIDGSDCCVEELALSYYGTLGYKGHHSENSILATLFALLFWDILFSPQPGVFETPFQTEPLDLRTDAFYLQRQEIIMDRIDNISRSKLISDEMEVCAVVAAQRNCRVAVEEVLEREKSFVREAHEEEEGEEEEELLVNPRRQQHDAKPRSQPRSVNQELKDNIMFEEEIQQELLQSAEQYSEERQAEILREKFLVRKRKECFYLDLLQKHDDLYREKKTFCVGVNWTFTKEELLEIAECIGGPALSEICKILAQEYGKRCSGMPDLCCWDYKKKLVKFVEVKGPGDRLSSKQQVWIDLLASLGVDVELCLVQVSKDEDTFLEERNALN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3C2</accession>
    <name>A0A9P6N3C2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Pre-mRNA-splicing factor SYF1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Pre-mRNA-splicing factor syf1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BGZ80_008474</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in pre-mRNA splicing and cell cycle progression.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Associated with the spliceosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the crooked-neck family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000046">
        <property type="protein sequence ID" value="KAG0023703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3C2"/>
    <dbReference type="OrthoDB" id="10067343at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071007">
        <property type="term" value="C:U2-type catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000349">
        <property type="term" value="P:generation of catalytic spliceosome for first transesterification step"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000023">
        <property type="entry name" value="Pre-mRNA-splicing factor SYF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000137">
        <property type="entry name" value="Pre-mRNA-splicing factor syf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000182">
        <property type="entry name" value="Pre-mRNA-splicing factor SYF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000038">
        <property type="entry name" value="Putative pre-mRNA-splicing factor SYF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003107">
        <property type="entry name" value="HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055433">
        <property type="entry name" value="HAT_Syf1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056350">
        <property type="entry name" value="HAT_Syf1_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055430">
        <property type="entry name" value="HAT_Syf1_CNRKL1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045075">
        <property type="entry name" value="Syf1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11246">
        <property type="entry name" value="PRE-MRNA SPLICING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11246:SF5">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR SYF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23231">
        <property type="entry name" value="HAT_Syf1_CNRKL1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23233">
        <property type="entry name" value="HAT_Syf1_CNRKL1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23220">
        <property type="entry name" value="HAT_Syf1_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00386">
        <property type="entry name" value="HAT"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Pre-mRNA-splicing factor Syf1-like N-terminal HAT-repeats" evidence="15">
        <location>
            <begin position="36"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="Pre-mRNA-splicing factor SYF1 central HAT repeats" evidence="13">
        <location>
            <begin position="200"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="domain" description="Pre-mRNA-splicing factor Syf1/CRNKL1-like C-terminal HAT-repeats" evidence="14">
        <location>
            <begin position="408"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="813"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="813"/>
            <end position="831"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00037272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00039472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00067212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF23220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF23231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF23233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0023703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="840" mass="97310" checksum="7933629CBE4677AB" modified="2023-09-13" version="1">MPGEKKATSKRGKAAAVVAPEPMDIVIEKSITISDKDVAFEEDLLRNPYSLRHWLRYLDHHSSSPIAQQFIVYERAVKELPGSYKLWKAYLDKRREHLANLDLPYVKAQADWESVDDCYERALVLLHKMPRIWIDYFEHLMATPRITKTRRTFDRALRALPITQHIRIWGLYLGWAKKIGGETALKVYKRYLKLEPNHGEDYVNLLILLERYDEAATRLCNLINDEQFQSMKGKSHYQLWRQLCDIICSHPKDIKSLPIEKIIRNGIKRFTDQTGRLWNDLAKYWILLSHFEKARDVYEEAITSVMTVRDFTQVFDAYAEFEESVISAKMEAAEAAEAEGEEVDQIDLDMRLMRLERLMERRPFLVNEVLLRQNPNSIHEWQKRVDLWGDNAQKVVETYTQAVTTIHPKKADGKFNTLWVNFAKFYEEGGDIPSARTIFDKATKVNFKTVNDLADVWCEYAEMELRNENYDAALQVMGRATVPSKQKNIAFHDETLPVQIRVYKSLRLWSFYVDLEESIGTVESTKAVYDKILELKIANPQIIVNYANFLEENKFFEDSYKVYERGIDLFGYPIAFELWNTYLLKFVNRYGGTKLERARDLFEQAIDKVPAKYAKPLYLMYGELEETHGLARHAMSIYDRATKAVASEDRADMYNFYIAKAATMFGVTSTREIYERAIEVLPDKDARVMCLRFADMERKLGEIDRARGIFAHGSQFCDPRISPEYWQAWHDFEVQHGNEDTFKEMLRIKRSVQVKFNADISYITAQMLQNQEKQKAAASTGDAMQSLDRMTSGGPGEMNFVKSKAHSVQVTHGDGVNDAPAAPAVPANPEEIAIDDDEDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3L0</accession>
    <name>A0A9P6N3L0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_000347</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000107">
        <property type="protein sequence ID" value="KAG0022389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3L0"/>
    <dbReference type="OrthoDB" id="2433856at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.120">
        <property type="entry name" value="BAG domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036533">
        <property type="entry name" value="BAG_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63491">
        <property type="entry name" value="BAG domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="229"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="301"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="450"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="93"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="311"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="464"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0022389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="489" mass="53559" checksum="F69FA07AD4DF0C85" modified="2023-09-13" version="1">MVSESTRKTLILSVSAIVGITTVSTLAYLLIQDDRRAKHHRKIRTLQKSLTHKLSKVETSIQELIDDDIRLAQVRARTLRTYPIYPGDPYVKSAIIEEDKIDLSEAIEETQEELTRERAQGYGDDSQKVRQGYKRLDFLIASVNERLLRQLEALDAISPRELTDLGNGSGGVVLASGPEVQAFEKVRKRKKAIIEKAQKLMAQMDKVSASFKDRLTAVEIYEKKEAEAAAAAKEEEEEKSEATTNSDNQHTNGEKTEPVRVKEGLSFAAVAKQNIPKPEVLEPTADLEKMKEGVTFAEVATANTQHENSDSSSTSTTTTSTTSITTTTTSTTRSIISNGSIGPLETEHLEGVTDGVSFADVASKHLDETEATEAKAEILEPTEDLERMKDGVTFAEVAAPPTAEVLKPTEDLEKMKDGLTFAEVAAPPTAEVLKPTEDLERMKDGLTFADVAATPATEEEQEEKEEKKEEEKPSAVVEGVSFAEVAAAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3N4</accession>
    <name>A0A9P6N3N4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Endoplasmic reticulum junction formation protein lunapark</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_011488</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Plays a role in determining ER morphology.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="1">The C4-type zinc finger motif is necessary both for its ER three-way tubular junction localization and formation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the lunapark family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000093">
        <property type="protein sequence ID" value="KAG0022676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3N4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098826">
        <property type="term" value="C:endoplasmic reticulum tubular network membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071788">
        <property type="term" value="P:endoplasmic reticulum tubular network maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903373">
        <property type="term" value="P:positive regulation of endoplasmic reticulum tubular network organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040115">
        <property type="entry name" value="Lnp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019273">
        <property type="entry name" value="Lunapark_Znf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22166">
        <property type="entry name" value="ENDOPLASMIC RETICULUM JUNCTION FORMATION PROTEIN LUNAPARK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22166:SF12">
        <property type="entry name" value="ENDOPLASMIC RETICULUM JUNCTION FORMATION PROTEIN LUNAPARK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10058">
        <property type="entry name" value="Zn_ribbon_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="Lunapark zinc ribbon" evidence="3">
        <location>
            <begin position="276"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="160"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="214"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="353"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="422"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="353"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="369"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU367073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0022676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="480" mass="53820" checksum="27D780BBE228DE4E" modified="2023-09-13" version="1">MSLDDSAAHSTWMQTKEKTQQQCHVRCSKSNDSDYEKILSDLDSNIRKAEVRLSAINVRERRLSSLWLIYSVLAWIGYIVVFALYLHPQYVDEPQPWAFALAPIVVGLPSIFVGRSLISVWYKRAKTNEESQLSLLRADQRLKVEELKKKTAYYSTKTLLERYDPSSKPSGLRQIGPDGRPIPNAQDGQPKLQQPNMMDPGLRQRQGMSVMNAQGIPVGQGHPAGVSSGVQRPGQGPQNDPRVQGNYGPQQPPHFNPGQPNGRPNQYGPPSTERHWYDKIVDVIVGDEGPDTKYALICGQCYAHNGLALPQEIEDIQYICPKCNFFNPPRRKTQKLQIPSTPEMTLLQARARPLPVSRDPSPSPSVRQSHQHQHHQHQHQHELDRPGLAEGNSLEPVSDLPIARDHMEHPETDEVEFVNNWNDSDAEGVNHDEGDDEEVDADGAKGYIVNSEEQPMATVTARETRSSSRKRSASATPKQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4C3</accession>
    <name>A0A9P6N4C3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WIBG Mago-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_004781</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000024">
        <property type="protein sequence ID" value="KAG0024267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N4C3"/>
    <dbReference type="OrthoDB" id="21625at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035145">
        <property type="term" value="C:exon-exon junction complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903259">
        <property type="term" value="P:exon-exon junction complex disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039333">
        <property type="entry name" value="PYM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015362">
        <property type="entry name" value="WIBG_mago-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036348">
        <property type="entry name" value="WIBG_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22959:SF0">
        <property type="entry name" value="PARTNER OF Y14 AND MAGO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22959">
        <property type="entry name" value="PYM PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09282">
        <property type="entry name" value="Mago-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01273">
        <property type="entry name" value="Mago-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101931">
        <property type="entry name" value="Pym (Within the bgcn gene intron protein, WIBG), N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WIBG Mago-binding" evidence="2">
        <location>
            <begin position="16"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="64"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="119"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0024267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="194" mass="21312" checksum="8819886DF369AE20" modified="2023-09-13" version="1">MSTPTESISGIQDKGDVRVIPMSRRADGTIRKERKVRPGYTPPEDVAKYTNRVLDAIRPASSISSLATPPVNSSSSSSSTPKTKSQIKNEKRKAKRKEEGPSETNQSKLEREDATKPSTDATPTTAIADTTTATAVAEFAPVDPEKKLRALNKKLRQAEQLKERQEKGEELLPEQLEKISKMDELQALIAELAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N545</accession>
    <name>A0A9P6N545_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007720</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000040">
        <property type="protein sequence ID" value="KAG0023846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N545"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0023846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="167" mass="18521" checksum="2C6643F71C0E7451" modified="2023-09-13" version="1">MSQDDSPVTSVGHGSSPDAGQDNAPAAGLNGTLDHRRDDDPENDVYNNTVSVLPITAIPRLQRDLDRVENDDLKNDVNDVSAIPIGSSICDGTESQPSILVDVTQKYLIEHVQMLEGDIDRLRRRVRSMERILNDHGTALSNIRKTIEVGKARKGNEERKKKKVRIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N548</accession>
    <name>A0A9P6N548_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_005884</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000029">
        <property type="protein sequence ID" value="KAG0024119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N548"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="197"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="302"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="241"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="197"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="316"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="340"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0024119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="820" mass="92850" checksum="CB498B1E218A2BB9" modified="2023-09-13" version="1">MAEEDSQHQLQQPHQGFIATIGGPCHGPVRVPVKVHERTGLKYIPMSSIRAMYPDMVRLEIEGETIKPNVGFDFHGIPGCPQAQWVPNHRNGGGMAIDEVMQESGVLAPRKLEDSFDFDFRAETEGGDNSVRIGHARSKEDNSAHMKSWPAKLAEKKVDKDLITVAEQLGFEIEWIHFYPGKSICVVHDCSSIKWPSSSEQQQQSQPTNSNPTSTLAPRPAVPQSTDMSESLFRQSWGEIKAFILEQNQELRQELKEMNNTIATSLQHQQVHPAINIEQSWPDALPTRTDGLRDRISSIGTKQLKAGKPAPHKSKSLSLLTNSSLKNSYPSQGKNSRLGRSCERYSGEDDCRSWSSRERHSAPSGAYIKPNDWPETSGIDQYIPRLDDYHAKDTKKSKVSSNSTEKRRDRMSFTNTRTFRFDEGDLVKFVEDCNGSILSDTLAVTISLKSPQEALSFYKFLASIDYRGRYLDIRLAWDWSQHDMEDLVSAIEVSNIRTLCLDCDKRSEPNKFIPSRSRHNPLVSLLGIRTLADLRLIAAPEILRESQVRIPSSMSHLSTLRIQLDASTQHVRFIDVIKRATCLRRLILDSLTNCYREYLELIKQALAQDRQAYEYHLHLPGTPTSMDIQFNHLEYAVLIVKIDRATGELREFSFDLHGAKADQVEWKPIFSSGVLAPLTSLTSLRLKNLNDGSWAPFLLGLTKAHNSFYDGHNERHLDVKRMKILDFRVDCKMVGSSGLQGMCDLIFYIRSTLLTLKLTNLSFPTIVSDEETMTSLKREGIKEEGELSSSSGSSETRNWAYFFKSLRFSVLERLQIEDAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N597</accession>
    <name>A0A9P6N597_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_007422</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000038">
        <property type="protein sequence ID" value="KAG0023891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N597"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="158"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="204"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="242"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="366"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="92"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="382"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0023891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="397" mass="44419" checksum="AA88E4E381F3C7E8" modified="2023-09-13" version="1">MDEMVVFPICKANGNKFSFGRPQPTVAQIDVSATATASALSNNMGETKAETSGTAMISTPSHFISIFPGPYPHMPNSNMYTAGQHARGNAPSREPSSSSSTSDSNARQNPDSSHVKQRNDARSSPFEGSWARLAASIDIMGSSEFASMILYPFANDRLLYYLLCRLQHLHLGFFLLGSASNVYMACKMLSDMYDLIITPPHSRYVKNFFLVQTSIFVIWFWFSYNLMAFRVSTTEEEFMSELPLWALRWINVGVAIVDLSYRRVYNRLGRLKVEEELLDISDVEKVEERQQKAWLYQQQRLLQFGQEQGQYLLDQFMALEVKQSILNGANAAVDVVSDVYSKTSIPSFPPIPNSLASAVTMMSATSSSNGNIRQPEVCSDPSGDHLTRQSQDIIKDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N761</accession>
    <name>A0A9P6N761_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_011323</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000009">
        <property type="protein sequence ID" value="KAG0024655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N761"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41390">
        <property type="entry name" value="CHROMOSOME 7, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41390:SF1">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 213 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0024655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="197" mass="21873" checksum="DA3EE4D6C5C4393D" modified="2023-09-13" version="1">MDAWHRPDKEVGKDLVKGTLVAGVAGATAGASIAFRESFLRFQRNKNPYYGFKDSQTMEIDQLWSSTVAGACTGGVLSALARGPKTVPSGTFMFGALAFGGQWILNKANRYRQEKILETIPLESTTAQAKGIHADSREHVGTGLLKVLPVHRTDVDDYEKRLLQKLELIEREQKILEEEVLRRKRIADSEATQEKSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SS10</accession>
    <name>A0A9P6SS10_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Arm-like repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007521</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003870">
        <property type="protein sequence ID" value="KAF9995411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SS10"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056251">
        <property type="entry name" value="Arm_rpt_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23948">
        <property type="entry name" value="ARM_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arm-like repeat" evidence="1">
        <location>
            <begin position="213"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF23948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9995411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="336" mass="37664" checksum="DCF77F49E9D3C983" modified="2023-09-13" version="1" fragment="single">MLRNLFSSQTSDRSTEETLGLTSKRLELARKEDDTAKRLELINSVKPLLKDTENTFASKKVKDPALSEGIANAYHEHGRLLDDLGHHDKAKKSRSKAEKWGYVDAVGRNIDSSHPLGKNNTVRRSLLPTAVPSIAPIVAVATPAKVKPTSPKNGMQIQQKIFDHNVTPPITKYALPEPDERITSTPQLAYCLSLLHSSMISQEELDQIERDWLQIKDVDPDERERLQTMATDLIRAFVREDLKKSSVIAEAVSLTAVLEQEVFRKLLQVFVNGISQSLLLDVHLLNGLAQLIRNAPEGYIDADDLVKVLELLNGRLKDTHKQSTRHTYQLAMTISQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SSN4</accession>
    <name>A0A9P6SSN4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CREG-like beta-barrel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007036</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003531">
        <property type="protein sequence ID" value="KAF9997328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SSN4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055343">
        <property type="entry name" value="CREG_beta-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37273:SF1">
        <property type="entry name" value="ADL397C-AP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37273">
        <property type="entry name" value="CHROMOSOME 8, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13883">
        <property type="entry name" value="CREG_beta-barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CREG-like beta-barrel" evidence="1">
        <location>
            <begin position="99"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9997328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="178" mass="20506" checksum="336AA0B5F86F8036" modified="2023-09-13" version="1">MPTSPCHDNSGPAAVLGETHKQAAGLARNLVKDTGIGTFMSVMDGRQMDGSLNGYPFGSMDYYVDDCDAPGTPLMLLSHLQVNVQNARTTNRVSLAIRKAEECFVKQHPEAKWWLPRNGFHDFKWYQLEIKEIYYIGGFGGIHYIGWIDVETYYKQQQQEEEEQEQEHLDSFWHFRQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ST77</accession>
    <name>A0A9P6ST77_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Anthranilate synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_006777</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003363">
        <property type="protein sequence ID" value="KAF9998485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ST77"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:L-tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.120.10">
        <property type="entry name" value="Anthranilate synthase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005801">
        <property type="entry name" value="ADC_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019999">
        <property type="entry name" value="Anth_synth_I-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006805">
        <property type="entry name" value="Anth_synth_I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015890">
        <property type="entry name" value="Chorismate_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11236">
        <property type="entry name" value="AMINOBENZOATE/ANTHRANILATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11236:SF9">
        <property type="entry name" value="ANTHRANILATE SYNTHASE COMPONENT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04715">
        <property type="entry name" value="Anth_synt_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00425">
        <property type="entry name" value="Chorismate_bind"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00095">
        <property type="entry name" value="ANTSNTHASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56322">
        <property type="entry name" value="ADC synthase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chorismate-utilising enzyme C-terminal" evidence="1">
        <location>
            <begin position="1"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="Anthranilate synthase component I N-terminal" evidence="2">
        <location>
            <begin position="244"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="Chorismate-utilising enzyme C-terminal" evidence="1">
        <location>
            <begin position="433"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9998485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="495" mass="54959" checksum="6BDB1625A30049E2" modified="2023-09-13" version="1" fragment="single">ASPEMLVKVQDRVVYTHPIAGTRKRGATPELDIALGQELLADPKERAEHIMLVDLGRNDANRVCKPETVKVDSLMHLERYSHVMHIVSNVSGTLRDDKTPFDAFRSIFPAGTTSGAPKVRAMELISELERTKRGVYAGAVGHFDYSGGLDTCIALRTMVIKDGVAYLQAGGGIVHDSVEEDEYQETINKLGSNLTALRSSPLANSHIISMAHSITVKPSLEEVQGIIESNAGNTIPIFAEIPADMLTPVMAYLKVSDKCDYSFLLESIAGGEKIGRYSFIGSDPYKVLKTGPEEALQGDPLAILEKELKNIRYVKVKGIQDFTGGAIGYIGYDNVQYFEPRTKRDDLQDPIGLPDAVFLFCDTIVIFDHLYQKIQVVTHYRSNVTDPAEVEKQYFKAVEEIQIIVELLENDVTPKIPQPPIILGQEPVSNVGKEGYEGFVTTLKKHIKLGDIIQAVPSQRLAKPTTLHPFNIYRHLRSINPSPYMFYLDLKDFTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ST91</accession>
    <name>A0A9P6ST91_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_006527</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003225">
        <property type="protein sequence ID" value="KAF9999646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ST91"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="380"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="148"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="388"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="401"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="427"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9999646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="522" mass="58774" checksum="A50373499E9D6AE0" modified="2023-09-13" version="1" fragment="single">MDLDSRLLESNEITEPGLQRRSIYTALLVYNRHIDSNTLYATSKSTFSNHYLQQPLTITNTTSSTHPNASSSAVQMDIDNIITVLTPAPAIAVFPLHFLIHNYEDNAAPQQLLLEGLQILRLNQNIAFQTLRTADDGEVTNQIKNDYLRDLENQLESYTQSIEEQRSLLHELQQLNNSISAVSTNPAPSKSESKEKDLTFPNDLSKFGEVGYRNAQEYIFTASNFLRLRRVNVDNPKTLASYLGMAIKNDKKRNEYTTNLFALEESADMTVDDVHKLGGRVYGTTAQTVATSKKLLEMRRRHDEIYHEFGSRTELQVKRTGTHDKTPAIISHLFSDASSLARTDLKLWLLVRDYKHCGLPFPDAEFTSLSDLTSAYQFLESPTRSESMDSSQSSSGYKNKSRSDNKRKSYSNRDRRDDSPSSAGSKRSSDNSAQKDNHKKARVQLVCTNCPHLSNHVTKDCKAPMCHTCRTRHSRYYCPKNNANATKPANNAIVALTPILISNEDGVTIYNDVMDLVNTLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWR3</accession>
    <name>A0A9P6SWR3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">DNA-directed RNA polymerase subunit beta</fullName>
            <ecNumber evidence="14">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="primary">RPA2</name>
        <name evidence="21" type="ORF">BGZ80_003777</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol I is composed of mobile elements and RPA2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:21249"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the RNA polymerase beta chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="14"/>
    <dbReference type="EMBL" id="JAAAID010002014">
        <property type="protein sequence ID" value="KAG0008170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWR3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032549">
        <property type="term" value="F:ribonucleoside binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006362">
        <property type="term" value="P:transcription elongation by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00653">
        <property type="entry name" value="RNA_pol_B_RPB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.270.10:FF:000006">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.270.10:FF:000011">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.150:FF:000004">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1070.20:FF:000003">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1100.10:FF:000008">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1100.10:FF:000016">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1110.10:FF:000007">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1800.10:FF:000004">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1070.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.270.10">
        <property type="entry name" value="DNA-directed RNA polymerase, subunit 2, domain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1800.10">
        <property type="entry name" value="RNA polymerase alpha subunit dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1110.10">
        <property type="entry name" value="RNA polymerase Rpb2, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015712">
        <property type="entry name" value="DNA-dir_RNA_pol_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007120">
        <property type="entry name" value="DNA-dir_RNAP_su2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037033">
        <property type="entry name" value="DNA-dir_RNAP_su2_hyb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007121">
        <property type="entry name" value="RNA_pol_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007644">
        <property type="entry name" value="RNA_pol_bsu_protrusion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007642">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037034">
        <property type="entry name" value="RNA_pol_Rpb2_2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007645">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007641">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014724">
        <property type="entry name" value="RNA_pol_RPB2_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009674">
        <property type="entry name" value="Rpa2_dom_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20856">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06883">
        <property type="entry name" value="RNA_pol_Rpa2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04563">
        <property type="entry name" value="RNA_pol_Rpb2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04561">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04565">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00562">
        <property type="entry name" value="RNA_pol_Rpb2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04560">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01166">
        <property type="entry name" value="RNA_POL_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 14 21" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 14" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 14" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RNA polymerase beta subunit protrusion" evidence="18">
        <location>
            <begin position="75"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="17">
        <location>
            <begin position="193"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="19">
        <location>
            <begin position="469"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed RNA polymerase I subunit RPA2" evidence="20">
        <location>
            <begin position="574"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed RNA polymerase subunit 2 hybrid-binding" evidence="15">
        <location>
            <begin position="683"/>
            <end position="1045"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="16">
        <location>
            <begin position="1047"/>
            <end position="1146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00025539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU363031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF04560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF04561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF04563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF04565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF06883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAG0008170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1148" mass="128156" checksum="B7B36156AB9913EC" modified="2023-09-13" version="1">MPPNAKFNTLERERIFKNPSDKSFQTPALQEMVAPHIEAFNALTEFGVGSKTGLLDLAIQDIGPKAVFDMHGGGLGNKLTFWVDEVSLSKPMLSDKERNSTTRQIYPTEARERLSTYRGKLQAKLAWRVNDGPVVVETRDLGLVPIMIRSNRCNLEGAYPKELIKHHEESEEFGGYFLVNGIEKLIRLLIVPRRNNVIALIRSSFANRGPTYSTYGTAIRCARPDQTSQTNTVHYLNDGGSMLRFAWRKQEYLVPTMLVLKALIDTSDKEIFDNIMLGDLENTFLTDRVELMLRSFKTYALNTREQCLAYLGDKFRVVMNFPEDYTDVEVGEGLLRKIILVHLKSNRDKFNLLIFMIRKLYALVAGECAPDNPDSPQHQEVLLGGHLYGSIIKEKIEDWLNGIRAQISQDVRRKIAGVDFLDNRYFTKTLLKTAGLQDIGQKMSYFLATGNLVSKTGLDLQQATGYTIVAEKLNFYRFLAHFRCIHRGSFFAELKTTTVRKLLPEAWGFLCPVHTPDGSPCGLLNHLSHTCKVITQPADVSRVPAILASLGVSQTLVPASGQKTVAVQLDGRIVGYCSSEEAKRVADALRHYKVTGAHQGAVPLDLELGYIPISQGGQYPGLYIFSTPARMMRPVRYLANGKTDMVGSFEQVYMEIACMDDEIHPNESTHQELAPTSMLSILANLTPFSDFNQSPRNMYQCQMGKQAMGTPATAIKYRTDNKMYRLQTGQTPIVRPVVHDTYGMDGFPNGMNAVVAVISYTGYDMEDAMILNKSSHERGFGYGTIYKSEIVDLGDLRIRGEPVLHHFGLGLDAPRSWREKLDKDGLPCIGVTLKEGDPICAYIDDTTGKTSIKKYKGLEDGIVDEVRLLGSDNGDSELQKIHIKLRITRSPIIGDKFSSRHGQKGVCSQKWPSVDMPFSESGIQPDVIINPHAFPSRMTIGMFVESLAGKSGALHGIAQDATPFTFNETFTAADYFGEQLKAAGYNYHGNEPMYSGITGEEFKVDIYLGVVYYQRLRHMVSDKYQVRTTGPVHNLTMQPVKGRKRAGGIRFGEMERDSLLAHGVSYLLQDRLMNCSDYSICNVCTKCGSITSPISTHSSSSLSNVREVECRACQTASSIDQIALPYVFRYLATELMSMGIKVTLKTQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SX49</accession>
    <name>A0A9P6SX49_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HECT-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="2">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">HUL4</name>
        <name evidence="7" type="ORF">BGZ80_002696</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010001676">
        <property type="protein sequence ID" value="KAG0009140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SX49"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2160.10:FF:000004">
        <property type="entry name" value="probable E3 ubiquitin-protein ligase HERC4 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2160.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044611">
        <property type="entry name" value="E3A/B/C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45700:SF8">
        <property type="entry name" value="HECT-TYPE E3 UBIQUITIN TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45700">
        <property type="entry name" value="UBIQUITIN-PROTEIN LIGASE E3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="HECT" evidence="6">
        <location>
            <begin position="408"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0009140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="648" mass="74451" checksum="F76017E4EC27B468" modified="2023-09-13" version="1" fragment="single">IIGKCLFCKSQLCYPQAVKVFQCVTCDTINDLIPSPGVVPEEPLTLQQIDQEIERARAKQIKTGGEMDYRDLETLLKEKLKKYAAFNASFSSGRPITYEHCGVNLADAKKAFSKLIAMPDTIALAVMTSVEAILKRPGKEIREKEDLKFIMLVFECPWLSRHRTPQESDYHHNITKRLFTIISNLPSELHKYLSNWFASMTTQIFHNRINFVNKFITQRLSNQQKSNDRHQHIIYQSDARIQAAARVMHLFFKANQPNEKELLDSSGKPRSFKDLVIIPNTNNSAVRSRRIPIDEYYNMIVDLIDLPADFVAWETRSAMFTFCQYPFLISMGAKMQIMAWDAKRRMEIKMQKTIEALLAQKRQRAIESGGDTNGTLLTQAELQQAPLLILRVHRNNLIEDSLTQLSRNEMDLDKSLRIEFIGEDGVDAGGLRKEWFLLLVRQLFDPQYGMFVYDDQSSHCWFNPASFESLDQFYLVGVVIGLAIYNSTILDLPLPLAVYKKLLNTPLALEDLAAFRPDLAKGFDQLLNYEEDDVEDVFCLTFVGVYEAYGESREIPLIPNGENIPVTNLNKRDYVERYANFVMNTSISDQFESFRRGFYLVCGGHALSLFRPEEIEFLVRGSAEPLDIDQLRSVTVYEGFNDEHDVIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXD1</accession>
    <name>A0A9P6SXD1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Mitochondrial K+-H+ exchange-related-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_002372</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001581">
        <property type="protein sequence ID" value="KAG0009461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXD1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902600">
        <property type="term" value="P:proton transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018786">
        <property type="entry name" value="Mit_KHE1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28062">
        <property type="entry name" value="K+-H+ EXCHANGE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28062:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10173">
        <property type="entry name" value="Mit_KHE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="112"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="301"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0009461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="320" mass="36467" checksum="4D0AEE9961F49024" modified="2023-09-13" version="1">MSRTAKVLHCHSTIPPNSTSYINRATNWAGRKWEELSKAKPDSMKIKLYTAGTTMMEKLDHQETFLKEVPGKRDVTITKMVPFVYPSSLKETQVQTDMKALLEQKIPYHRKYMIYSALWVPVTSLFIIVPLVPNIPLFYNTFRLWSHWKAYNGAKHLDSLMKDGGVVFQPSDVLNLGLDHDPEFAVFFTGSNQLSKRRRPRKKYDQQDPKSPIITESSGEDTPTLLNGVHNGVATGNTEIQKPAHHSTTVRDDDPLSMTDHVVMEGFITDKEVELICETFKQAPSMSREIKRARRQEAEKFIKEKIAAGPTDKDKETSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXE4</accession>
    <name>A0A9P6SXE4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">TM2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_002002</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TM2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001480">
        <property type="protein sequence ID" value="KAG0009848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXE4"/>
    <dbReference type="OrthoDB" id="408511at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007829">
        <property type="entry name" value="TM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050932">
        <property type="entry name" value="TM2D1-3-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21016">
        <property type="entry name" value="BETA-AMYLOID BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21016:SF25">
        <property type="entry name" value="TM2 DOMAIN-CONTAINING PROTEIN DDB_G0277895-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05154">
        <property type="entry name" value="TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="104"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="131"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="TM2" evidence="8">
        <location>
            <begin position="101"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="22"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF05154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0009848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="167" mass="18552" checksum="074D4CC45BB08596" modified="2023-09-13" version="1">MATSYGTTNAAPAAHHDEESQALLSSQRQPTNTEANDTFYGRTYGHVATHRKRYFALWVLAAIVAISTVVGLHYYEKQHRGHHDDPHDPSGLIKPEYCESDRSYPIAILLSIFFGYVGIDRFYLGYVISSLLKLATGGGFGIWYVIDILLIILGDLPDHNGCRLVAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYG3</accession>
    <name>A0A9P6SYG3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Golgi apparatus membrane protein TVP38</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Golgi apparatus membrane protein tvp38</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">TVP38</name>
        <name evidence="12" type="ORF">BGZ80_000452</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Golgi membrane protein involved in vesicular trafficking and spindle migration.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TVP38/TMEM64 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001095">
        <property type="protein sequence ID" value="KAG0011741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYG3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051076">
        <property type="entry name" value="Golgi_membrane_TVP38/TMEM64"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032816">
        <property type="entry name" value="VTT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47549">
        <property type="entry name" value="GOLGI APPARATUS MEMBRANE PROTEIN TVP38-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09335">
        <property type="entry name" value="VTT_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="22"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="61"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="96"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="170"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="208"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="VTT" evidence="11">
        <location>
            <begin position="83"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF09335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0011741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="285" mass="31526" checksum="D40B1C57697762D6" modified="2023-09-13" version="1">MAAESLPTIGERLRAMTITQKVALAIFCVIMIAFIIVFFAYEKQVFELLEPAVDYIRKSSAGMVVLGAIMAATCIFPLFGYGAVSMICGYVYGIPMGFIPAFFGDIIGASAGFCKYIFRKFGDNIEFREMSKAVSTDGIFILFLIRLSSFPFAVLNAYFGAMTQLPYWKFILATTLSTPRLFLPIFIGQNISSLADPTVTGNSRIIKWAASIAGIIIALAVGWYIYRHTTRRIERINAGLAEENEDVGGAVRHTRAAQYDAVINMEEIERIQDPPQVQPLVLPPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYZ8</accession>
    <name>A0A9P6SYZ8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Casein kinase II subunit alpha</fullName>
            <shortName evidence="8">CK II alpha</shortName>
            <ecNumber evidence="8">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">CKA1_2</name>
        <name evidence="11" type="ORF">BGZ80_011472</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Heterotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CK2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="8"/>
    <dbReference type="EMBL" id="JAAAID010000925">
        <property type="protein sequence ID" value="KAG0012851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYZ8"/>
    <dbReference type="OrthoDB" id="10254671at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005956">
        <property type="term" value="C:protein kinase CK2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051726">
        <property type="term" value="P:regulation of cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006356">
        <property type="term" value="P:regulation of transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006359">
        <property type="term" value="P:regulation of transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14132">
        <property type="entry name" value="STKc_CK2_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000059">
        <property type="entry name" value="Casein kinase II subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000088">
        <property type="entry name" value="Casein kinase II subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045216">
        <property type="entry name" value="CK2_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24054">
        <property type="entry name" value="CASEIN KINASE II SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24054:SF0">
        <property type="entry name" value="CASEIN KINASE II SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 8" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="41"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="337"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="347"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU369118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0012851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="357" mass="41789" checksum="1DCE759DD9805B3C" modified="2023-09-13" version="1">MSKVKLPNSIARVYADANERLGRDYWDYETFSLQWGVQDNYEIIRKVGRGKYSEVFEAINITNNEKRCIKVLKPIKKKKIKREIKILQNLAGGPNVIRLFDVVRDPQAKTPALIFECIDNDDFRTLYPKFRDFDVRYYMMELLKALEYCHSMGIMHRDLKPHNVMIDHSRRKLRLIDWGLAEFYHPGTMYNVRVASRYWKGPELLVDLQDYDYSLDMWSLGAMLAGLIFQKEPFFRGSDNNDQLIKIAEVLGTEELFKYLNKYALELEDHHDVLNEYIPRTPWQKFVTADNQHLVTNGALDLLGKLLRYDHQERLTAAEAMEHPYFDPVKTRAATAVEGSLTTTDSSDTDDWSEILN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZC0</accession>
    <name>A0A9P6SZC0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Mitochondrial carrier</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_011381</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000907">
        <property type="protein sequence ID" value="KAG0012984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZC0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050567">
        <property type="entry name" value="Mitochondrial_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624:SF26">
        <property type="entry name" value="CARRIER PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G07710)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624">
        <property type="entry name" value="MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="385"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="559"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="651"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="421"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0012984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="727" mass="80466" checksum="D6B3173FD34EE1B3" modified="2023-09-13" version="1">MNNHDTIVPALMANMALCKRNTYWRHGENATRDPLYAIQSSAKSHTGNVEASILSRAKDGILLFELDQLDKKSLSHVAPILSTIDGEDINVQFEDSTQALSLVCCCWSTYTKIDDPPRYKESNPPDDGNIGGPGKGVSMIGTFDIVISQNEMDGASDTSRAVSSHTLRRCMGVSSDFVGETQSSIDFSTLCFRSIATRDDALIRQTVGQDGLNAHVLEYSEYELELETDVPTVAEACVPVTLEERRDSVASSMNGHATKGGTMTRSIVAYAMSEHGDNKEAVRGSATVGVPTAVARSMLVQALQFWYRVPIKLFRPMRVDYLVMARAATLGLIPAPSHRQAYVEQSNKLLSKRSQFFRATSIGMLTHTIRTQGAGFVYRQVLPPLFMNTFIGSVLYTTYIFTLPIFHPAFTYQKSRTFPPPPFPAVFMAGAIAGAAQSLVAAPMDSVKVKFQIQDVATGGKHKSITGFAISTLKDLGLRAVYRGYTLILVKDALACGLFFGVFEWVKQQGYYYFMDELYGIRDELESLKAQEISDSSRSISALESASSLLPDSPRPRPYFFLEPTFVLLAGAAAAVAYQAVDYPLEQIRSIFLAKEAELMAEKSRHPQQPHSQRLNASSMRSGSAISSQLYEMTWNECKANASSSGGWRRFLFSNFAMTAIRAVPAASIGFLVFEVMKRKLDARMYESEDREIAWFLDQMMKEREAERMAELKAAEGLVEREIPVFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZD9</accession>
    <name>A0A9P6SZD9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_011291</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000893">
        <property type="protein sequence ID" value="KAG0013092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZD9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050562">
        <property type="entry name" value="FAD_mOase_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356:SF2">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356">
        <property type="entry name" value="FAD-DEPENDENT MONOOXYGENASE ASQG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="13"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="309"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0013092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="466" mass="52527" checksum="DA9166AC3EB9D8FD" modified="2023-09-13" version="1">MEQQVPMATPRPEVFIIGAGIAGLTLAILLEQINVPYHIFERASEVRPLGSAMALEGNIFPALEQLGIYEELQQVSKTYVSVDFYNAELKKLGCVNIKENRVASGYHNLIFSRPKLYEILLRRVPAHKMTFRKKVLRTEESDSKVTIYCSDDTSYTGDILVGADGTYSGVRQNMYKHMDEKGLLPKSDLEEFSIGYTTIVGVATPPNPEKYPQLSAEHSCFNQIIYKDGANASIPWIANCYVVAGADNQISWGFGQQLSESYLRDLQFRNSEWGPEKDDNTLEQYRTFPCPLGGTLGDLFDATPKNLISKIYLEEKLFKTWHHGRTVLIGDSCHKLHPAGGQGARNAIQDAIILANCIYSMTDFSSADINAAFEDYYKQRYHHAEVAWNVSSGSSKILSGQKWWERFARYLVLNYLPDWLMRVNTQREMSYRPQVAWLPLIENRGEGHVLPQGFESVEAPAVAVGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZL6</accession>
    <name>A0A9P6SZL6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein nedd1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">NEDD1</name>
        <name evidence="2" type="ORF">BGZ80_011012</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000832">
        <property type="protein sequence ID" value="KAG0013544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZL6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005814">
        <property type="term" value="C:centriole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000922">
        <property type="term" value="C:spindle pole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043015">
        <property type="term" value="F:gamma-tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007020">
        <property type="term" value="P:microtubule nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052818">
        <property type="entry name" value="NEDD1_Spindle_Assembly"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44414">
        <property type="entry name" value="PROTEIN NEDD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44414:SF1">
        <property type="entry name" value="PROTEIN NEDD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="276"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="331"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="361"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="574"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="641"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="279"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="331"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="361"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="397"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="414"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="435"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="450"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="466"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="512"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="577"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="608"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="644"/>
            <end position="660"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0013544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="763" mass="81647" checksum="78DC93EBB7F21535" modified="2023-09-13" version="1">MLAVEAQDGRIFLHDSRGRFQESLVNELIMEESRSGSNRCVMSWAPKPQRLYFAMGNKVMTWDSTSKRTAETFEMTSRISALGVNNEDILLAVGQNTGSVDVVNRSTGVSARLETPASLIMAKLEYSVFSKSILGGVGNDGVLRLWDTGSTGSTAIYHSFAATHEVPISGMAFSPFNRYLICTAGLDKRYALYDVEKKNVVKNTLTEYALTSVSFKNDGISMAFGTDQGKVLLYDLRSTSRPISIVDTRVNAPVTAIHFQGKQSSTKRHQTINGHALKRQNSTGSQTSAFSMKDSTTTAASADPITNSEKTAAPARHVPVKMATFSHSTLNRLSSNGASQPTKEARSSSVIDFFSSRRSSDLASSNLMSSSGTTGSATAARQDDKISSKPRRPTAPTLNTTTGGLTSVTSSTSKPAISSRGSSMPTTPSKEYPYASSGGNANNINGSSSHPNSRTVSPFAFQTMQSRSPSGESSSSSSSVGTPPGSPGGHVEFGTSSSNQNHRKHHHYQYHSSDSLSKSPSRSSRAKRRKSFGTLMASGGASSIPGTPDLFSDEKMEVLRGQIVDRVRDVLLDHPSEPTTIRSNYNNNGSAKSRSGSQNEMRSSSEKSAAGVTASSASVITQKPGPKARAPVKDLWLQVGQEGGNSSQQMSKTQSASSLGRSTLAASTSLPATTIGVIPSSSLSSSAMVTDPSAALSSNGFSSKVLENVVEGCLMDFRAGIRNDIQNMHLELLRQFQIQKIEIETLLKQYSDTKELREENERL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T010</accession>
    <name>A0A9P6T010_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_010253</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000696">
        <property type="protein sequence ID" value="KAG0014740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T010"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0014740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="452" mass="51275" checksum="5B3A69E4709187BB" modified="2023-09-13" version="1">MANLHELREIAFLIGKFIPVWLKGRDDYYEYRFYPKDLLNCCFVCRAWRSAMLPWLWVLFEETKMGKVPNDILLKYSPYFKIIGYSYKRETLSYAIIHAEGLRDIKISYMYDDMILPVLNTHPGLRSLSISSKESHIDSTIVLPLGNLSSLVELEIGSTIMTFQELAAILENKPKLQTLSLDSIEINDEPPEDSSNLELPGLTALHITSTQINQGVIHRLLECSPALRTFTLYLNSDEGFQASECVNVLRRNNPNLESLLVQDHYSLEELDVMIEKASPLVKDICVDVDCLEVSTFRAIASRADTLEKLTIKTGGAHLDMINLSRCTRLRELHILVDNLTTIGHSKRIAQILCDKSWSNPNMTHFSIRGLRPQTSTAAGVALPQGWIILPADDLFAPLGRTFPRYSEVLSAQPLISGLDAQLLETFEEMAHIQEVVVNELKYKRLVIDHSRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T072</accession>
    <name>A0A9P6T072_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Acidic fibroblast growth factor binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_009823</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000622">
        <property type="protein sequence ID" value="KAG0015503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T072"/>
    <dbReference type="OrthoDB" id="16955at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008614">
        <property type="entry name" value="FIBP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13223">
        <property type="entry name" value="ACIDIC FIBROBLAST GROWTH FACTOR INTRACELLULAR BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13223:SF2">
        <property type="entry name" value="ACIDIC FIBROBLAST GROWTH FACTOR INTRACELLULAR-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05427">
        <property type="entry name" value="FIBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0015503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="371" mass="43391" checksum="689CB4443EB5E799" modified="2023-09-13" version="1">MTEWMVTTSSAVVLDESILQLWLLGHSVDQATVARLPMIQPPVSSRVLKSYITSQYRTYEMMHHYLHHPRHFAGQFMFPLSHSAKQHLIERYYSFDESVIREILGKKLNSRTRKDLDEVHEKTGVKLTSCRRQFDNLKRVMKKVEDAEGRTLIQDIEHQFLLPHYLARQYAHILFIADKKLDTFRKRLSCYQYSDFEYCGAVLMQYWTASTMDTLPEFDPQLAQDVRDLKSLMLNDRAVLDELRNRISNNLSQSAHPPVLERIQSNFKVVLRNMLSIGCMINQQKEVRNILVEITDKLVDAFIQVGWSSTDIGAFYDSMVAEFQNTASLTSRYRERYSTSWIRLVTGIKLTSIRLYKQPTSQSILTRSFTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0B1</accession>
    <name>A0A9P6T0B1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_009636</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000595">
        <property type="protein sequence ID" value="KAG0015785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0B1"/>
    <dbReference type="OrthoDB" id="2438715at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="260"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="465"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="164"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="263"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="468"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0015785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="493" mass="54681" checksum="E1E1723A9E9680FD" modified="2023-09-13" version="1">MGVATVHYDSYQYRAKSGIRETNSDTELDGNETADLRRSSISINTSSSPTKVFKRHAPQLSEVSDVDGLSGNEMCEEPKSFSNSIPKTRRKPFETGEDCQDIDLGNTFDADMAMILGMTSDMELVMPNFDDEYLEDLKNDPVLAEQSRWPSTVSTVSSSYSHCSSTTMACSSSQPSPRSHSGTPSATTDEASCRAESLPVSPGTLAARTHIQSHDASHVNSRLSQPSDSSVHSPAQDLSIIHQDIDHLRRHRDSLKHNTDMATNSLSKSSCSSSHTTTSENQSSPSEYPRQNITIIQSNQWTFDNEGSSRARAFPPRSIQENCAMQGNDENQTFRVREHSYLPAQPQPSQVHSPLNKSTMMTENNISLVTANMSVLTPQEVQEDYYTRRNLRVCRQRQRRRSAISDRGSIVGPLFGSTEGFSPWARRFSTSDVHPLEKLIMPAIGANPLPASYYIPPSAFRTEATVAAEKEAERKRREQEEGSLLFFPSPTLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0P9</accession>
    <name>A0A9P6T0P9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_009149</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000525">
        <property type="protein sequence ID" value="KAG0016532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0P9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="47"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="177"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="295"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="325"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0016532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="458" mass="50588" checksum="577EB16626D013DE" modified="2023-09-13" version="1">MAPSSCFVDPMECIFEKPSIQILQKRAPPPPDDAPTTGAIPPVSHTVVIASAVAGTVLLILSISFIYCCMRKRRASRRIGQLQKFLPTFMDQEKTEKYFQKQGSSTTLVATPSLKEKELVPPSNAHHRTRSVPVAFAKGVTDHRNRQLERDGSLGQFQQISLVSEETVLEKDEPELTRSSSGRSTRARSSTTTVASPAAVKSSLHRSVSLNKRSSQRTAGSRSDPMEEEEVDQSERFPEGESLVAPNRFSTLLDFGNGNNRFSAQSIIDMDPNFDPTRFSSASIMFDAKRLSNASISSEDSVSTNSSDEFRKNLPPHQLQPSFHSHVDTPIERSNEVSAEAPAPMAPNHPSYSGDKQELEEDEEYIPQPPNFYNTQVQDHQRQPYPPMHQNRPMAMPTPMHMSMPMPMPVPIPTPAVTPGSQGRTGSPLPPLPPRIMLSKPHVGQEMSMVVDDRGASH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T116</accession>
    <name>A0A9P6T116_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribose-5-phosphate isomerase</fullName>
            <ecNumber evidence="4">5.3.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">D-ribose-5-phosphate ketol-isomerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Phosphoriboisomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">RKI1</name>
        <name evidence="9" type="ORF">BGZ80_008417</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>aldehydo-D-ribose 5-phosphate = D-ribulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:14657"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="ChEBI" id="CHEBI:58273"/>
            <dbReference type="EC" id="5.3.1.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate degradation; pentose phosphate pathway; D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ribose 5-phosphate isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.6" evidence="4"/>
    <dbReference type="EMBL" id="JAAAID010000455">
        <property type="protein sequence ID" value="KAG0017312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T116"/>
    <dbReference type="OrthoDB" id="1555531at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004751">
        <property type="term" value="F:ribose-5-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006014">
        <property type="term" value="P:D-ribose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009052">
        <property type="term" value="P:pentose-phosphate shunt, non-oxidative branch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01398">
        <property type="entry name" value="RPI_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1360:FF:000014">
        <property type="entry name" value="Ribose 5-phosphate isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.260:FF:000053">
        <property type="entry name" value="Ribose-5-phosphate isomerase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00170">
        <property type="entry name" value="Rib_5P_isom_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020672">
        <property type="entry name" value="Ribose5P_isomerase_typA_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004788">
        <property type="entry name" value="Ribose5P_isomerase_type_A"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001924">
        <property type="entry name" value="PRK00702.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00021">
        <property type="entry name" value="rpiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11934">
        <property type="entry name" value="RIBOSE-5-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11934:SF0">
        <property type="entry name" value="RIBOSE-5-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06026">
        <property type="entry name" value="Rib_5-P_isom_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75445">
        <property type="entry name" value="D-ribose-5-phosphate isomerase (RpiA), lid domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0017312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="236" mass="25330" checksum="01D0F7D9EBE4AFC3" modified="2023-09-13" version="1">MTSLIEQAKQKAAYQAVDEHVLPSHRVIGVGSGSTVVHVVARLLQRDPELNAKTVFVPTSFQSRGLLLDGGLNVGDVDQYPDIDVTIDGADEVDSQLNAIKGGGGAHLQEKVVAEAAKKFVIVADYRKNSKILGEQWKQGVPIEVAPFAWRVVLVKIQNMGSKDAKLRMAVAKAGPVVTDNGNFLIDAPFGLIQDPANLLKDIKLITGVVEVGLFCNMAEIAYFGNEDGSVAIRTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T138</accession>
    <name>A0A9P6T138_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">3'(2'),5'-bisphosphate nucleotidase</fullName>
            <ecNumber evidence="3">3.1.3.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_008434</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>3'-phosphoadenylyl sulfate + H2O = adenosine 5'-phosphosulfate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:77639"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58243"/>
            <dbReference type="ChEBI" id="CHEBI:58339"/>
            <dbReference type="EC" id="3.1.3.7"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:77640"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>adenosine 2',5'-bisphosphate + H2O = AMP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:77643"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:194156"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="3.1.3.7"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:77644"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>adenosine 3',5'-bisphosphate + H2O = AMP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10040"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58343"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="3.1.3.7"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:10041"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the inositol monophosphatase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.7" evidence="3"/>
    <dbReference type="EMBL" id="JAAAID010000457">
        <property type="protein sequence ID" value="KAG0017289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T138"/>
    <dbReference type="OrthoDB" id="411145at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008441">
        <property type="term" value="F:3'(2'),5'-bisphosphate nucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000103">
        <property type="term" value="P:sulfate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01517">
        <property type="entry name" value="PAP_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.190.80:FF:000003">
        <property type="entry name" value="PAP-specific phosphatase HAL2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.540.10">
        <property type="entry name" value="Fructose-1,6-Bisphosphatase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006239">
        <property type="entry name" value="DPNP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020583">
        <property type="entry name" value="Inositol_monoP_metal-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051090">
        <property type="entry name" value="Inositol_monoP_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020550">
        <property type="entry name" value="Inositol_monophosphatase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01330">
        <property type="entry name" value="bisphos_HAL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43200:SF6">
        <property type="entry name" value="3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43200">
        <property type="entry name" value="PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00377">
        <property type="entry name" value="IMPHPHTASES"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56655">
        <property type="entry name" value="Carbohydrate phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00629">
        <property type="entry name" value="IMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00630">
        <property type="entry name" value="IMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="10">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="275"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR600760-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0017289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="337" mass="35903" checksum="7188D563C77CD88E" modified="2023-09-13" version="1">MSALAYAAERAVAIRAVLAASGVCQRVFTKLVNGETITKKDKSPVTIADFSAQAVVNTFLHQSFPADPIVGEEDSKDLRGEEGRVMREKVLELANTGLDSPLTEETLIETIDRGTFAGGPNGRMWALDPIDGTKGFLRGEQFAVCLALIVDGQVQVGVMGCPNLPVDAKNQNGEKGCLFITVKGQGAFQRNFSSSTETPISMSDIQSLADASFCESVESGHSNQSESAKIAQLLGITKAPVRMDSQCKYCSISRGDAEVYLRLPVSASYEEKIWDHASGSLLVAEAGGIVSDVHGKPLDFSKGRTLATNSGVVATHAEIHGKVIEVVQKVLFPEGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T145</accession>
    <name>A0A9P6T145_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF7137 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_008197</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000438">
        <property type="protein sequence ID" value="KAG0017512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T145"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055561">
        <property type="entry name" value="DUF7137"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42028">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42028:SF1">
        <property type="entry name" value="YALI0E30657P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23585">
        <property type="entry name" value="DUF7137"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040230560" description="DUF7137 domain-containing protein" evidence="2">
        <location>
            <begin position="30"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7137" evidence="3">
        <location>
            <begin position="130"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="51"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0017512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="218" mass="22388" checksum="A9FD3C63C73CD389" modified="2023-09-13" version="1" fragment="single">MYYKSGSKAWILLTLIALVLVALLPTASASEIHRPRLYARQQQGQPSRVSPSTPTDTNGNGGSSSSQPSSAPVPSSSPSPPSKQPGSSGGVVIGSGSSNSTLPPLGSTGGTVIGTGGTIITGGTVIDPRLPVSHLSMVQPKQNSANPPLFPVGSYIVFEWVFDNTTLVFVPATLTVEVSLTSNPKMVWSVANVSGTATSVVWNTGAVVSPSLFMGFYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T208</accession>
    <name>A0A9P6T208_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Translation initiation factor IF-2, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BGZ80_007535</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000388">
        <property type="protein sequence ID" value="KAG0018116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T208"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01887">
        <property type="entry name" value="IF2_eIF5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03702">
        <property type="entry name" value="IF2_mtIF2_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03692">
        <property type="entry name" value="mtIF2_IVc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000007">
        <property type="entry name" value="Translation initiation factor IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000008">
        <property type="entry name" value="Translation initiation factor IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10050:FF:000001">
        <property type="entry name" value="Translation initiation factor IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000019">
        <property type="entry name" value="Translation initiation factor IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10050">
        <property type="entry name" value="Translation initiation factor IF- 2, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00100_B">
        <property type="entry name" value="IF_2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053905">
        <property type="entry name" value="EF-G-like_DII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044145">
        <property type="entry name" value="IF2_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000178">
        <property type="entry name" value="TF_IF2_bacterial-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015760">
        <property type="entry name" value="TIF_IF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023115">
        <property type="entry name" value="TIF_IF2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036925">
        <property type="entry name" value="TIF_IF2_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43381:SF20">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR IF-2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43381">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR IF-2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22042">
        <property type="entry name" value="EF-G_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11987">
        <property type="entry name" value="IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52156">
        <property type="entry name" value="Initiation factor IF2/eIF5b, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Tr-type G" evidence="13">
        <location>
            <begin position="414"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="72"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="671"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="35"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="87"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="128"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="170"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="231"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="255"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="296"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0018116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="962" mass="103753" checksum="3CE0FC174ED96D6D" modified="2023-09-13" version="1">MWKVSRFSCSSRLRPSRQGSSTYTLGYRGFRSDTGRNLNANTNGNGSNGTVNSGKLVGERIVIDPKTKMRMDLRKETIGDSNGKLSSGKDKWAQSPDHAARVQESPFRRAYEESMNRSSRTRGGGKSNSGQQNKAQESQRLGRFYNERNGSSGRQNPPSSFATSSAWGFSAPTPSATPKSGAPSPSSSTKPSASRSSAPSPSTAAVPKPSNVTQTSSSTTNSAPSLPPTPQRTSIEATNEVKSALPAAPAPAVPSPKAVPLNTVNPAASSPNSSTSAASNPTPIAPIMTREPALKQGTQTFVRSTRTAKENAQIQVEQRSRKRRQQQKPPKDVFIPEAISVSNLAGLLGARIGHFENTMKTLGMEIIRHDHILTSEEASLLALEYNVNPIIGTTEKLFDLTSQPEPEDMSIHPLRPPVVTIMGHVDHGKTTLLDSLRKTSVAAGEAGGITQHIGAFSVILPSKQRITFLDTPGHAAFSAMRARGAHTTDIVVLVVAAEDGVMPQTAEAIKHAEDAGVPIIVAINKCDKYGAEPDKAKQALLKHGITVEDLGGETQCVEVSGLTGKNLDKLEEAILTLAEVLDLRAEVDLRGEGHVIESQIEKGRGNVATVLVKRGTLRVGDTIVAGDAWCKVKALVNDTGKNVKEAPPGTPVKVMGWKDLPMAGDEMLGAESEEQAKLAVANRALKKERQEQLKALVAINEKRRITAEEEDEEKEALKEFKRKTWLFHQGMLDTYPDPPQVKKQLSVAAMAAKEEEESEVKNLRMVVKGDVSGTVEAVCDALSGLPANQVKVGVIQSGVGNITESDIQFASSCNGFNVKADKKLLQTARQMGVSIKSYNIIYKLLDDVKIEMATLLPKDIEIQVVGEAKIAQVFPIKMKGQTQNVAGCRITNGGVTRKEDVRIVRNGEVIWNGRLATLKRVKDDVQEAKKGTECGMEFDGFQDFKEGDVIQSIKKMEVLRKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T274</accession>
    <name>A0A9P6T274_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DNA damage-binding protein 1a</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">DDB1A</name>
        <name evidence="7" type="ORF">BGZ80_007070</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000356">
        <property type="protein sequence ID" value="KAG0018515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T274"/>
    <dbReference type="OrthoDB" id="433457at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018846">
        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058543">
        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050358">
        <property type="entry name" value="RSE1/DDB1/CFT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004871">
        <property type="entry name" value="RSE1/DDB1/CPSF1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10644">
        <property type="entry name" value="DNA REPAIR/RNA PROCESSING CPSF FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10433">
        <property type="entry name" value="Beta-prop_RSE1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23726">
        <property type="entry name" value="Beta-prop_RSE1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03178">
        <property type="entry name" value="CPSF_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RSE1/DDB1/CPSF1 first beta-propeller" evidence="5">
        <location>
            <begin position="13"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 second beta-propeller" evidence="6">
        <location>
            <begin position="456"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 C-terminal" evidence="4">
        <location>
            <begin position="838"/>
            <end position="1150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="163"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="169"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF10433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF23726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0018515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1188" mass="130075" checksum="6C67B2758AFA8EF6" modified="2023-09-13" version="1">MNIVFTARKSSAVFQAIKGNFTGPEDLNLILGKGTRVEVYLIGRDGLKLIKEFGIYGEIVCMEPFRPPGHITDMLLLTTTHYQMLTLSLRLTSADGSAQAGDITSIASQFNIVSDSLTDLQDRHARPSDHGQIVIIDPTSTIVCCHLYQGLLKCIAVNPHTPLPPGANGQQQQQQQHQQQHSGRGSSSHSSRSSSRLVDKTFLDHYNVPIEEITIMSMVFLHGCQRPTLAVLYQDKKEIRHVKTYEFDLKTNDKSETGWMQSGLTGAVTCIAVPSPIGGFLVVGEYSISYFNPALPSPPRSITINATIMQCYNRVDDQGIRYLLGDHKGMLYILVLILNNASGTSTSQSNRPFQVVDLKFEPLGTTSIPTAIVYLDNDHAFVGSHLGDSQLVLLHTEPDQNGEYLEVMETFTNIAPVTDFEVVDLEGQGQGQVVACAGGFKDGSLRIVRNGVGINDRAVLELPGIKGLWSLKENLDAPIEDTLVMSFLNSTRVVRVTSDAEMVQEEMEGFLNDSQTLLSGNVQAGLILQVTPESVRLIAPSQHIQAGLISEWKPLSGQFISVASMNATQCLVAVGGKTLVYLDIGSEAIREVRRTTFENEIACVDVTSIDLANPHASQVCAVGLWTDIKVILVRLPTMETLASHSLPGEILPRSMLLSRFEGVPYLLVGLGDGQLLTFVLDAALSTLPTPKRISLGTQPIMLRQISSGQGKGETGGTSNHVFACSDRPTVIYSSNRKLLYSNVNLKQVATVTSFNCEVFPGALAIVGSDEEAVLRIGSIDEFQELHVQTFPINESARRIAYLASRKCFGVISIKVVNDEPESVGNSMIETSEEQELGFVRLHDDQTFDLLHTYELQTEEAPQCIAAVTFAGDPTSYIAVGTAESESDNMPAKGRILILEVTENSQLKLVTELEVKGGVMAIKEFQGKLLCGVNEQLRLYSWKTGDNLTTESNLTQECSHRGFILILSLATHGEFIVAGDLIRSVTLLRYIDKKIVEIARDPNMDMLTAIEIIDDETFIAANNASSIFTLIKNTETTSEDEAKRLQWSGGWHMGDQVNRFKHGSLVMANQENDAPAVPKLLFATVSGAIGVVATLTAEKYELLHHLETNMSSVIKGVGGLDHASWRMFRSDARTLPSSNFVDGDLIELFLDLSQDEINNVLEGPEDGKPIKVPVDEITKLVEELSRLHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2G6</accession>
    <name>A0A9P6T2G6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_006382</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000315">
        <property type="protein sequence ID" value="KAG0019045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2G6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0019045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="232" mass="26305" checksum="CCE448C39093D46E" modified="2023-09-13" version="1">MPRGALDHSLSSCNNLNSLCLQSPGTVDVTYDAFRLYFHSLTSLDTKSCGAFSSRVVQDIMTSCPSLKTLRAYMLMAMDVLGEEEIADLRSGSPSDRRPRDWVCLGLETFSVCITEFMNDSYYRLIFQRLAKLTRLEVLDVGTGDKGCMKYDVSCLKFRIDHGMGALVSLRRLRWLGLTGLRQQMDVADIQWMLRSWPHLERVSGVSNTNRLQVDGLEAELQKRGFIKRDTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2W1</accession>
    <name>A0A9P6T2W1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Serine aminopeptidase S33 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003421</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000190">
        <property type="protein sequence ID" value="KAG0020889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2W1"/>
    <dbReference type="OrthoDB" id="435520at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050471">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43433:SF10">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43433">
        <property type="entry name" value="HYDROLASE, ALPHA/BETA FOLD FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine aminopeptidase S33" evidence="1">
        <location>
            <begin position="73"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0020889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="379" mass="42725" checksum="0C3E24D7F45CEE48" modified="2023-09-13" version="1">MSRRMSEAASVCSFDSIPTMADVEATLGSVDMNQRYELYSGRLISFAEVGHPCGHPVFCFLGLGCMRYYSIILEDLAFKHQLRIYCIDRPGVGMSHTTEPEAWTPLRMAEIVEEMANGFNIQRFSVMGHSCGAIYAMACALRLKSRIVGTVWLMSPWVHLTLAKRMKWIKHVPTTLLKSQSTASLLYKSLSVAAKEPPSSSDPNILNYDREKLCKAMLEDNMAESLEGANNDLMVCLELYHSFGFSYKDVKLPVHVFWGTKDAVISREAVDWMEQKLEQCTLSVIEGGTHGLLWRADVVSQMFKGIASSWKLAEFERSLSQRWSIKQLGLNSSGNRHLAYRSSAYNATVQQAIQTSNIYESLQQASLHPHQVLEDPERF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T317</accession>
    <name>A0A9P6T317_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_004555</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000231">
        <property type="protein sequence ID" value="KAG0020238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T317"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="122"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0020238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="338" mass="36287" checksum="FE754D11AD751E48" modified="2023-09-13" version="1">MAYDPTSCIVATNGTIVMASTSGVWSLPYQSNTLTWTSRQPPSLLPNLPTPILACTVANSKLYAVLQGNATLPTIRSIDLRSSSWDWQKVKLTQVPGNGDNGDPFDSNAGNSNSMNGLSTGAIVAIVAVAVVLLLLGLGFFWWRRRSTKRMASGTGEIEKAGSTVLGYATPATQQTRSWETRPSKQELFEQPNNGHQQTQPQVSRSWSSNSVITADRPYGNLSYQQPYAAYPLHQVGGNVPAIVTSMPNTVADRYVHSSSSPMGSNHAGDKQELTSEDQVITPASTASNTFITPHMPDASSQTNGHISPNDPRTMEMLSPGLANAQLILQQSQAPQNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T393</accession>
    <name>A0A9P6T393_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_002073</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000150">
        <property type="protein sequence ID" value="KAG0021606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T393"/>
    <dbReference type="OrthoDB" id="10261384at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11960">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019341">
        <property type="entry name" value="Alpha/Gamma-adaptin-bd_p34"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14659">
        <property type="entry name" value="ALPHA- AND GAMMA-ADAPTIN-BINDING PROTEIN P34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14659:SF1">
        <property type="entry name" value="ALPHA- AND GAMMA-ADAPTIN-BINDING PROTEIN P34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="336"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="423"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="456"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="68"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="99"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="342"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="461"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="471"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0021606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="563" mass="62530" checksum="1F3B936F9C1FF7A1" modified="2023-09-13" version="1" fragment="single">MDNPPRNKILVVGRRGVGKLSLVQSILGSRFVPTTSVSKSRPSSPLILPAIPVPTIEETIVDGHGGLSQSISASAPPNAPSTQSSLPGNSFTTLPASPLLQRQRQFQLEQDQSASGNGFQASQTREKLDHSGVTIPWTIDTKYYSVKVDFWIDETDSQGKAELDRMIEFGELDEMGAVVEAVVFCFSKNQPSTFHDIKPWLNFVERHEPSIILCVATSAPGAETQDMVQDLSMNDETIVDYDDWCLGNGFEFIDLDDQPSDMTQDEHVGLDRIMEALAAHMWDGLKRKSSKKRDQHDRSMMMSFRDDDVDMTYDSSWRGNISRRSLLGLEAGDLSVIHDHDDMQEDDDDDDDDEEDGDDDRAFYRALQELNLHNRTASPTAPTRGPMASQLLNEHLGVNGQGDNSMGFDDDFGLSEQEIKELERDDNEIWSSQDTSKSERIAPIDRALEKQFKQYLGQPLDDSTTTSSDNGAKDTSGELDSSDKEFSFELNDDDEFEFGSFIVSAGPGGEDLEHFDFKFDGEDAITTSTSNQESIKSMHKALFANIDDDDGMAQTIATLQGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T485</accession>
    <name>A0A9P6T485_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transmembrane protein 41B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">TMEM41B_2</name>
        <name evidence="9" type="ORF">BGZ80_008103</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TMEM41 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000043">
        <property type="protein sequence ID" value="KAG0023776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T485"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045014">
        <property type="entry name" value="TM41A/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032816">
        <property type="entry name" value="VTT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43220:SF18">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 41B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09335">
        <property type="entry name" value="VTT_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="202"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="243"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="VTT" evidence="8">
        <location>
            <begin position="125"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="314"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="315"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF09335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0023776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="346" mass="39365" checksum="3A5772A323B121C0" modified="2023-09-13" version="1">MDQQYEHEQSRPLLTGSPPPRAYETTPNNASVIASEAIGYHPEYETDSDDDDEIGPPKIPAWKAWLHTIFKFFQGLGKFFLILALGTIVLIVVLQYTLPSVDEEHRKDIHFPHSLEDLEALRKILIASAVGATNCYLLSRLFFSKLVKRKFGERMEKWNTQLEKHRNDLISYIILLRLAPFPPNWFVNICSPHLHVPLWPEFFIGTLIGVTAPSVVHVQAGMVLEKLVEDHTSGVDIFTLKNIGMLVAVALLAALPVLIRWILARREARKVGIHVDALGHEEEGEINPNDLNPILEPLDPTGLIISPERQHFLRRSSSSFSRTGQQQHLQSHPQQQPQQQEQYQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T4S4</accession>
    <name>A0A9P6T4S4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial</fullName>
            <ecNumber evidence="9">2.3.1.29</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">5-aminolevulinate synthase, mitochondrial</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Aminoacetone synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Glycine acetyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BGZ80_008583</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the synthesis of 5-aminolevulinate (ALA) from succinyl-CoA and glycine, the first and rate-limiting step in heme biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>glycine + acetyl-CoA = (2S)-2-amino-3-oxobutanoate + CoA</text>
            <dbReference type="Rhea" id="RHEA:20736"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:78948"/>
            <dbReference type="EC" id="2.3.1.29"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="8">
            <dbReference type="Rhea" id="RHEA:20738"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.29" evidence="9"/>
    <dbReference type="EMBL" id="JAAAID010000047">
        <property type="protein sequence ID" value="KAG0023669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T4S4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008890">
        <property type="term" value="F:glycine C-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006783">
        <property type="term" value="P:heme biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006567">
        <property type="term" value="P:L-threonine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06454">
        <property type="entry name" value="KBL_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000004">
        <property type="entry name" value="2-amino-3-ketobutyrate coenzyme A ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000006">
        <property type="entry name" value="5-aminolevulinate synthase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00985">
        <property type="entry name" value="2am3keto_CoA_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011282">
        <property type="entry name" value="2am3keto_CoA_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001917">
        <property type="entry name" value="Aminotrans_II_pyridoxalP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050087">
        <property type="entry name" value="AON_synthase_class-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01822">
        <property type="entry name" value="2am3keto_CoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005394">
        <property type="entry name" value="PRK06939.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693:SF102">
        <property type="entry name" value="2-AMINO-3-KETOBUTYRATE COENZYME A LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693">
        <property type="entry name" value="CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00599">
        <property type="entry name" value="AA_TRANSFER_CLASS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="13">
        <location>
            <begin position="52"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00052559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00067076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00069660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00075633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00078624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0023669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="414" mass="44797" checksum="BFED1682F76F0220" modified="2023-09-13" version="1">MASTKAQTQFNQILKTEIDSIKAAGTYKSERVIVSPQNSAITVADKDGKTTPQINFCANNYLGLADHPEVIARSKKYLDTHGSGLSSVRFICGTQNIHKDLENQITKFYGTEDTILYASCFDANAGIFETILTDQDAVISDALNHASIIDGIRLCKAKRFRYKNCDISDLETQLKEADKAGARLKLIATDGVFSMDGKIAPLDKICDIAEKYNALIFVDDCHSTGFLGPNGRGTAEYFGVQDRVHIVNSTLGKALGGAAGGYTTGCKEMIDLLRNRSRPYLFSNSLPPAVVGSASAALDLIEGAKTNGLFDQLWGNTTLFRKLLTEAGFTIKGDNHPITPVMLGDARLAGQFADEMLKRGIYVVGFSYPVVPKGEARIRVQVSAAHTEAQIRQAANAFIEIGRELGVIGAKSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MEA2</accession>
    <name>A0A9P6MEA2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8">Malate synthase</fullName>
            <ecNumber evidence="2 8">2.3.3.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_007795</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6 8">
            <text>glyoxylate + acetyl-CoA + H2O = (S)-malate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18181"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.3.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Carbohydrate metabolism; glyoxylate cycle; (S)-malate from isocitrate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the malate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.9" evidence="2 8"/>
    <dbReference type="EMBL" id="JAAAID010004051">
        <property type="protein sequence ID" value="KAF9994501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MEA2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005782">
        <property type="term" value="C:peroxisomal matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004474">
        <property type="term" value="F:malate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006097">
        <property type="term" value="P:glyoxylate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1220.12:FF:000001">
        <property type="entry name" value="Malate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.360:FF:000001">
        <property type="entry name" value="Malate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.360">
        <property type="entry name" value="Malate synthase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1220.12">
        <property type="entry name" value="Malate synthase, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044856">
        <property type="entry name" value="Malate_synth_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011076">
        <property type="entry name" value="Malate_synth_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006252">
        <property type="entry name" value="Malate_synthA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019830">
        <property type="entry name" value="Malate_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001465">
        <property type="entry name" value="Malate_synthase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048355">
        <property type="entry name" value="MS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046363">
        <property type="entry name" value="MS_N_TIM-barrel_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42902">
        <property type="entry name" value="MALATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42902:SF1">
        <property type="entry name" value="MALATE SYNTHASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20659">
        <property type="entry name" value="MS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01274">
        <property type="entry name" value="MS_TIM-barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51645">
        <property type="entry name" value="Malate synthase G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00510">
        <property type="entry name" value="MALATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0329">Glyoxylate bypass</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Malate synthase TIM barrel" evidence="9">
        <location>
            <begin position="29"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="Malate synthase C-terminal" evidence="10">
        <location>
            <begin position="280"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="33"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="315"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR601465-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF20659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9994501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="352" mass="39905" checksum="EF19F9338A7BF06C" modified="2023-09-13" version="1" fragment="single">MKDAIHQRISYTAPNGKQYNIRKDGKVATLIVRPRGWHLDEKHVLIDGEVTSGSLFDFALYFFHNAKKSVEIGIGPYFYLPKMESHLEARLWNDVFNLSQDYIGMPRGTIRGTCLIETIMAAFEMEEFIYELRDHSSGLNCGRWDYIFSVIKKLRQNPKFVLPDRSDVSMTTPFMDAYVRLLIKTCHKRGVHAMGGMAAQIPIKNNEAANKAAMDKVYNDKLREVRAGHDGTWVAHPDLVTLALKVFNEHMPQPNQLHIRRDDVHVTAYDLLNTHVQGGKITEAGIRANVSVSLIYMEAWLRGAGCVPIHNLMEDAATAEISRSQLWQWAKHGAKTDQGVTVTPQYLAKVLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MEQ7</accession>
    <name>A0A9P6MEQ7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_007539</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003881">
        <property type="protein sequence ID" value="KAF9995355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MEQ7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9995355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="106" mass="12334" checksum="3B5BE9D6F8E5EB55" modified="2023-09-13" version="1">MAEDLGPHFPYEYILKIYIAALMETIGSHMALIQFIIRAENQLSLEVSETFTIRTDTPVSVVAFRNFWIVNRDEMARRADELMDRLKLRESIGDRAKKITSDGWQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MFH4</accession>
    <name>A0A9P6MFH4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HEAT repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_007161</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003617">
        <property type="protein sequence ID" value="KAF9996809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MFH4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004155">
        <property type="entry name" value="PBS_lyase_HEAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12697:SF5">
        <property type="entry name" value="DEOXYHYPUSINE HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12697">
        <property type="entry name" value="PBS LYASE HEAT-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13646">
        <property type="entry name" value="HEAT_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00567">
        <property type="entry name" value="EZ_HEAT"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9996809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="433" mass="47802" checksum="3598C2CB2E030B45" modified="2023-09-13" version="1" fragment="single">ALVGALQDKDEDVRERAAEALGRQSTLPESAFQALIGVLQDKDEDVRRRAVEALGRQSTLPESALQALVGALQDMDEDVRKEAAEALGKQLSLPESALQALIGALQDKDWIVRNSAAYALKQSTLPESALQDFIGALQHENEDVRREATEVLRKQSTLPESALQALICALKDKDEVVRKSATEALGIQLKALIDVLKDKDWRVKELATEALGMQRILPESAHQDFIGALQHENEDVRSVAEALETQSTLSESALQAFIGALQDKDWRVRNLAAEALGKQLTLPKSTLHALIDALPNEHARYSAADILEKQSTLPESALQALIGTLQNKDRDLQRCVVRLLLRHVETTFMVIPSLSPSAIETLYRDFLIQYSSKYSASLWVQGHQVHFHTVQGPGKIDGLCVEDVTKVVQAFNQAQKRAILPLVEDCNQVLEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MFW0</accession>
    <name>A0A9P6MFW0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Chitin deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">CDA2_5</name>
        <name evidence="6" type="ORF">BGZ80_006844</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003400">
        <property type="protein sequence ID" value="KAF9998212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MFW0"/>
    <dbReference type="OrthoDB" id="407355at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004099">
        <property type="term" value="F:chitin deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009272">
        <property type="term" value="P:fungal-type cell wall biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050248">
        <property type="entry name" value="Polysacc_deacetylase_ArnD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10587:SF133">
        <property type="entry name" value="CHITIN DEACETYLASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10587">
        <property type="entry name" value="GLYCOSYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040297216" evidence="4">
        <location>
            <begin position="21"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="domain" description="NodB homology" evidence="5">
        <location>
            <begin position="120"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="337"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9998212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="395" mass="41908" checksum="D0368A1356E08987" modified="2023-09-13" version="1">MIANLSLIAAVLALAGTSSAATTTTTAATTTATPAPLLTLKPFNGTFAGDYPTTFEVAPTNTTLAKQWIAQYNTANITSLPVVPFTSGGDPKDPNSISADACDWTITNCINKDITVCPIGVWGLTYDDGPTEFSTQLYDYLDTTEQKATLFYIGSNVITNWEAARRACGAGHQIASHTWSHQPSTSLTNEQFIAEIKYTEMAIKEVCGFTPKYFRPPYGDIDNRIRSLLWAMGYTSVIWDYDTNDWQMAPGGTRTLAQVNADFATWEAAASNDTTGHITLEHELYQNTVTAAIDNLPKLAATWKLMPVSACMNDSHPYQETEYQLATMNGVVTGMSSATTSTNTTTSSNTTSTAAAGASGASSTGGKTSGAVAVTGEMKVFALVAAAAAAAAQMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MGG5</accession>
    <name>A0A9P6MGG5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">dynamin GTPase</fullName>
            <ecNumber evidence="3">3.6.5.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="primary">MGM1</name>
        <name evidence="20" type="ORF">BGZ80_006762</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.5"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="17">Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.5" evidence="3"/>
    <dbReference type="EMBL" id="JAAAID010003356">
        <property type="protein sequence ID" value="KAF9998532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MGG5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061024">
        <property type="term" value="P:membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031623">
        <property type="term" value="P:receptor internalization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08771">
        <property type="entry name" value="DLP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000741">
        <property type="entry name" value="Putative mitochondrial dynamin GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022812">
        <property type="entry name" value="Dynamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001401">
        <property type="entry name" value="Dynamin_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019762">
        <property type="entry name" value="Dynamin_GTPase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000375">
        <property type="entry name" value="Dynamin_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030381">
        <property type="entry name" value="G_DYNAMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056495">
        <property type="entry name" value="LIS_MGM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566">
        <property type="entry name" value="DYNAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566:SF212">
        <property type="entry name" value="DYNAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01031">
        <property type="entry name" value="Dynamin_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24550">
        <property type="entry name" value="LIS_MGM1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00195">
        <property type="entry name" value="DYNAMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00053">
        <property type="entry name" value="DYNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00410">
        <property type="entry name" value="G_DYNAMIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51718">
        <property type="entry name" value="G_DYNAMIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="13 17" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="6 17" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Dynamin-type G" evidence="19">
        <location>
            <begin position="94"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="605"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="36"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="605"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="18">
        <location>
            <begin position="635"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="20">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="20">
        <location>
            <position position="755"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU003932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAF9998532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="755" mass="84515" checksum="4D8A877224FE7596" modified="2023-09-13" version="1" fragment="single">ESPAGIDAQDGPRFIRKSSTGGNNNNDEDPQHNSGAAAAAAAAAAAAVLAKSKSEEQEGPRSSGIPPHDGDFMLLTKKLIEVRNVLNSIDHNDTLKLPSIVVIGSQSSGKSSVLEAIVGHEFLPKGSNMVTRRPIELTLIHTPHSKEEYGEFPALGLGKVHDFKRIQQTLKDLNMAVPESECVSSKPIELRIYSPNIPDLTLIDLPGYIQITSKNQPLSLKEKISELCDKYIKEPNIILAVCAADVDLANSEALRSSRKVDPLGLRTIGVITKMDLVEPDRGVAILRNQDYPLHLGYIGVVCKAPSGGSKDNMTQAVIKTEDAYFRSAYQFSQRGVAVGTGTLRRKLMDVLEENMGSNLGSIIKAVQKELDETRYQFKVEYNDQKMSAESYVAESVDKLKHRFKDFSRAFGKPQVRLEIRHMLEQRMLDICAQRYWSDPRISELSQLDSAAEEDRLYWDLQLDLASSALTKSGVGRQTTQRVVDILSKTMEQLAEAEPFNHHPDAAITIKSMTHEILSSRSQATTDQVENTIKPYKYEVECTDSEWSEGVKRSITLLQTELEMCEEALTKIKSTVGSKKLRKAINYVLESDREEERRAKRREAFAKLRESNLRQRSEESSSDKENDNNGSGSESSEQDLESREDEVERSQEEDELEAAMRPHFNPKLLVKAREALSLRDRALILKYRLTALKSKACKNSKNKTQCPEAFLAMISEKLAYTSVMFIQVELMNEFVFQLPRMIDSRLGVKIGQEAME</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MI00</accession>
    <name>A0A9P6MI00_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ankyrin repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_006007</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002966">
        <property type="protein sequence ID" value="KAG0002214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MI00"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="124"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="9"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0002214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="179" mass="19242" checksum="3D4B59530B686B73" modified="2023-09-13" version="1" fragment="single">MLSSIGKIFGGRTEPDGGNDSPGGTPSEVSEALIKEFFGAIQEHDSDTVRRLLVDHKTDLTSARFKPDPQSVSFPPEIERDAYTLLGAYLGPLTGLQYSILTGKDDIALDILDATFEQDAKFGSGNTALHLAVLLGETAVVSGLIERGADMNLKNKRGYSVVDMSDNPDILRLLECAEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MLU4</accession>
    <name>A0A9P6MLU4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_004862</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002432">
        <property type="protein sequence ID" value="KAG0007282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MLU4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040327652" evidence="3">
        <location>
            <begin position="31"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="202"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="268"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="385"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="162"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="273"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0007282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="420" mass="44533" checksum="ED34065FC567F230" modified="2023-09-13" version="1">MLYSRKPRAASALLSLGVIFFTGLLSAVQATLQCAQPNNGTYSAGDSLVLNWSSDGSSPTVQDIKSMSATLNCNNGISIANVTITTWNAPYTWTVPSVGNATTAGGTTGTCPSNSFHVEYTGVATVTVLGFITQEKAFTISCDTITILPAANNSITTTTATTTTTVATTKSKTTSSTSTSSSSASPTPSNVTSDDDSKPKTFIIVIVAIVAGLILFLVAFASWWYLRNQRIKRMEDAVMPWSNQPGSQFSKVSSMDEGHRAPGSINGAAAVSNKPQPMTPQPQKSYYSGDEYGSQYGLGGGYDNYNNGNNQDEYYDPYYAASRAGYGASPLNSNTTYYNNSTPYLDPRDPYQQPAPTGYFPPPPPVVPSPMPSTVSQLNTVSEIAPSSGSLRGPQVILPEKGSPSTEDDIQMKVLMKSSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MM26</accession>
    <name>A0A9P6MM26_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_004842</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002424">
        <property type="protein sequence ID" value="KAG0007296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MM26"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056251">
        <property type="entry name" value="Arm_rpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23948">
        <property type="entry name" value="ARM_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05729">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arm-like repeat" evidence="2">
        <location>
            <begin position="183"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="domain" description="NACHT" evidence="1">
        <location>
            <begin position="641"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1059"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0007296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1059" mass="120371" checksum="EEA5EB8F2382C7FB" modified="2023-09-13" version="1" fragment="single">MGWCCCCVTFEDALEVANKKIEIAQKNETPVKDKRQLGNDAKKKIIKAEDILKKEKRADDAAAKSRLANAYHEHSILMLALEDNASAEESHVKAISLDYVHLIGEKPRSSLCPRPAVRNDSGNDISRIKRIFPQDIKPPVAKYKLPEPGSRLEATTQLTYCLSLLRTDESFDIKRDQSELQWQSTEDQAEYERLNSLAAAVTRAFIRDELKLPTTVREVVCLAPVLGRDEFRGLFRSFVGGIDSSKLQDDVLLDGLAQLIRNSSLDNFDVDDLLKILVLLSDRLQETNSKSRYNYQLAYTTSRVLDSIMDSQIDSLDRDRIHAPLLDHLKGLKSDSDPYLVFQAAYAIQALVYIGDGETKVQKFLRRSGKVVKGISGIVAAVKAIDLNSFIESLENIQEGLAGATVAYHAVVLANSGKAFHECVKDAFNFDNRSVWYPALRGLDSLIQDGRFADFEKLIRSAPCQMDPAYQWGVCQRLGEIANNPLWDIKTRKCAIEFLAEMYEDDMTWGIQVNVKQWILYILSQLKKSDAAIASHVEVTLVGLAKNGDSGKQALYQAYLNNQPRSYPLVAAFQPNEFPLLKIVQDTPNVELAINQLRQERLKSRDTNVYISPIAKASLEETEYFDLMLKVHEFLKSERKVFLLRGSSGSGKSSFSRALEIDLWDAYKVGGAIPLFIHLPDFDKPEQDLIEKRLSKANFTDNLIRELKLNRQLILICDAYDEIQTLQNLYTRNRLNEQGEWCAKMVIACRTEYIGKDYKDFFQPSDRNHAEDSSLFQEAVIAPFTEKQIHEYIDKYFSKGEPKKFTRAFKEIPVLKDLVKNPFVLKLSVEVLPQIMKSSTSLSSERITRVKIIDEFVALWLKRNKKRLTNMTLTPPDDKKLQRLVRDGFEEHAVCYTKELAVAIYLYQNGHPLISFSGVNDRGTWKEWFFSNLDGKDLLRDSIPLTVSGNQYQFIHKLYLEHGLSLAVFDPNVDLLRETKPQSHPISHMDVALSAELDRSPSVEKKVNLAQKKLLDSPLGTMHLAGNPSTTDCFEFLVERAHEHPLFRTNLLEVIEHSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MM55</accession>
    <name>A0A9P6MM55_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_004590</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002323">
        <property type="protein sequence ID" value="KAG0007507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MM55"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0007507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="734" mass="84361" checksum="CA77A542A8128D07" modified="2023-09-13" version="1">MARSRSIESIQAAVSEDSHLHNDFETLRSLLYVDKFFFRAAIPYLIKDHISRSVKDWLHNRSRSEKLFALILASFLEARLKKLRDPHDASELAEIVLEKILERFGLRLVKPFTLPGHQMLRSFLRRIDDMPKNHDYDCNNRKYGGEYGQEFDGNAPEEMDSGMIIDYSKFIPKIPGPFDGSTMQATKEHGGWVSPELYIQSDYGRLEKHSVDHQVEDDYLNELHKAFSKLWQHYNHECTDSFTLDIANAQRFLPFSKEMPKLHTLCLDRYSKMTASHLKNTVLFIKQNQETFPNKPPLYIQFGLDQWDLPEESYSSLGNNSLKTALAEIKCRRDELFQYMKPLITIHEAVGEPPFFNISNIPYFYEHADGIKLNRLWGLSDFDENRIDQGEGPAIEPSLRRCSALKVLWIGAGSPDILSWAANEVMGTDGFLALESGNESMSNTNVLEKIEPIKISNDSKQHSQQNPQTRVAQLQVKILGCIESLSIRSSRPYRFGLQIINDASIAFSTSLRVIGITAGDDHYFSSSDVPAVVRRQHFKKSFQLHDVSSANGVGSWPFFMPRLQKIHINLSRVASIQVGTFDQSPNIEDIDIEFGSVTAYDCRPSDDRPLPPPESDEYLDYRWLQPKIDKSLFPIWNLQKLKKLKLYNLAASRFDFASLSNTPCLEKLDLGAYYIRADPLIGVNEYKNIQIRVWKERLTLGTDNDTTRYKPAAAARPWMWPLPVLSVRHWKRLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMC2</accession>
    <name>A0A9P6MMC2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BGZ80_004216</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002176">
        <property type="protein sequence ID" value="KAG0007796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMC2"/>
    <dbReference type="OrthoDB" id="270584at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000016">
        <property type="entry name" value="Solute carrier family 25 member 23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24089">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0106">Calcium</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="EF-hand" evidence="14">
        <location>
            <begin position="150"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="14">
        <location>
            <begin position="269"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="14">
        <location>
            <begin position="305"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="12">
        <location>
            <begin position="371"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="12">
        <location>
            <begin position="509"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="12">
        <location>
            <begin position="662"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="207"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="35"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="63"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="80"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="122"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="210"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="241"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0007796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="754" mass="83426" checksum="26393A2859176F7F" modified="2023-09-13" version="1">MPTAVDPGPTKEESKDRTSIKLMDLPMQPKKKKSENKDSTKQSDPESSDTGDDALSKKTGPVTTLAAPASSTTALSQSSIPKQNPDSPTPSGHSNNTKSNSTGDHSKQDSFVHHQQLLDQLHQKEEKEEREERDQRKYKVTYPHFETREERQIRIRKQFDQLDAKRSGVVDANSLVVFFADITPDKDVQRRYADELLQLCHSKILTRSNHGGEDGGEHSDHTGSDLTEHEDGQESQQSQHPHQHRRNHSHPRQHNGHVNYDDFEVFVEEKEERLWNLFREIDHNNDNEIQPEELQASLAKLGINMSEADLHRFFKAMDKDDNGAIDFEEWRDFLVLLPRETTLKEIYHYVQEVVAQVGVDGDVVMPPSENDYVARYLLAGAIAGAVSRTATAPLDRLKVYLITKSVPALTGPAAEAGLKHIPKLSGSSAVAPVKQRLLWTSITELYNQGGFKTFFRGNGLNIIKIAPESAIKFYTYETSKAFIVSHLPSFTVQHHYHDGSGVNQHPPDIATSGRFLAGGVAGLVSQFSIYPLETIKTRIMSSTGGSQQGQAITSTAKSPVSISASASGSASTSSSTSSLLATQTSTSTKPCRLNMQTVIREIWQKAGLRGFYRGLGPSLVGIFPYAAIDLSVFETLKFGYMRWKAGVHEGDKGSEEKALDRPSVFVLLACGTISGSVGATSVYPLSLVRTRLQAQGTPHHPQTYTSTLDVFRKTYAKEGVRGFYKGMVPTLTKVVPAVSISYVVYEYSKRELGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMC7</accession>
    <name>A0A9P6MMC7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glycerophosphocholine phosphodiesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">GDE1_1</name>
        <name evidence="7" type="ORF">BGZ80_004345</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002223">
        <property type="protein sequence ID" value="KAG0007702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMC7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057506">
        <property type="entry name" value="C2_GPCPD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030395">
        <property type="entry name" value="GP_PDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25329">
        <property type="entry name" value="C2_GDE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03105">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51704">
        <property type="entry name" value="GP_PDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="SPX" evidence="5">
        <location>
            <begin position="1"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="417"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="459"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="527"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="599"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="domain" description="GP-PDE" evidence="6">
        <location>
            <begin position="911"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="692"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="692"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="951"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0007702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="951" mass="104723" checksum="8809D6B2896F3069" modified="2023-09-13" version="1" fragment="single">MKFGKAHVRNQIPEWSRHYISYKGLKKDIKNGRETLESGDTSLEDIVTAFIFHLDREVEKANNFFIYKRSELERRLRILSEKSRRINPTNISNGTAQPIANSLAEAETAADQKLSTNTGVRPRFDLSIVTSPPRAIPTGNASMVLPSPFISDPEADAECLQAMIETKEMLSKLSWFAEMNRRAAQKILKKFDKRMRTICRDDYMSTKVNTLPFVTDGQLVEMNITIDVLIRELKAVVADYPPFPLGSPKHASNESRMGLNEQQIEDAMKAIGRDDVDTLKSIFNTKLKEYPELQNALSSSVKSGRLGQLPRLLFRKACEEKAFQCIALILSFGTGALYVNVNDQTVLHRLAIEGGIYTKAPAEDGNSLHQTNSCNEHTQRHITPKDDPELITFILKQISSYTEENSLCTLKSTADIFGRRPLHYAAMHGHANIAKALIKDLKASGEFINFSDPYWFDTDGFTPLIYAVSRGHATTLKVLIEEGEIKDVDAISNAYISHASLPKVMPSAVKTVLNPLVGSDVNLHAAYTYTPLSIACRLGHVEAARLLVQFGANLDSQDEDGESCLIIASKNGHIECVKLLIVGAGNGTGANLELRERYYGWTALHLAAIENHAEVVKVLLEAGANPNVYDYSSWNPHEHAVFAANTACAALLRPVSRNLDDRQRLQKSNAGGDSGQGSPILGNFSFPQPTIASRSTGNSGSMSPKSQRVDSPPVSSGKNSGKHLKTAHRAYGHKYLEDESLIVVTLGSNDIRSTVEPVELYIVDGNHSFLTASTAFSIEITAGNAAAGEKVIVDLPLKDSSHHEQIVFYAAKPEDAIINFSVYPTFGPSSSKMVGRGTAILSSLDNLRRDVWNQQSMMTPLQGMNMTVPIFGVEGMEIIGRVRAEFTVVRPFKHENLKVGSKHTYWKSVTTTVIGHRGLGMNRKVSNLQVGENTLLSFVTAASLGAEYVEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MN51</accession>
    <name>A0A9P6MN51_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DIS3-like exonuclease 2</fullName>
            <ecNumber evidence="5">3.1.13.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_003497</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="5">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
            <location evidence="5">P-body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the RNR ribonuclease family. DIS3L2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.13.-" evidence="5"/>
    <dbReference type="EMBL" id="JAAAID010001929">
        <property type="protein sequence ID" value="KAG0008395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MN51"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000956">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990074">
        <property type="term" value="P:polyuridylation-dependent mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.700:FF:000002">
        <property type="entry name" value="Cell wall biogenesis protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.690">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03045">
        <property type="entry name" value="DIS3L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041505">
        <property type="entry name" value="Dis3_CSD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028591">
        <property type="entry name" value="DIS3L2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041093">
        <property type="entry name" value="Dis3l2-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001900">
        <property type="entry name" value="RNase_II/R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022966">
        <property type="entry name" value="RNase_II/R_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050180">
        <property type="entry name" value="RNR_Ribonuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23355:SF9">
        <property type="entry name" value="DIS3-LIKE EXONUCLEASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23355">
        <property type="entry name" value="RIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17877">
        <property type="entry name" value="Dis3l2_C_term"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17849">
        <property type="entry name" value="OB_Dis3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00773">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00955">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01175">
        <property type="entry name" value="RIBONUCLEASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RNB" evidence="7">
        <location>
            <begin position="296"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="166"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="771"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="178"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="776"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="795"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="308"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="317"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="5">
        <location>
            <position position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0008395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="866" mass="97477" checksum="938DFBC93520807F" modified="2023-09-13" version="1">MSTSIATPVASNGGFSNRDSVSLKDNTNGRRPLFQAHLTYSDFHSLLTKQKHKYVQGVLRINKRNRSDAYVTVDSLPEGDVYICGSKDRNRALEGDVVGIELIDFEDMPLQKLEGGKEKKKNKRVEDVEEAGEADVEDIKPKYCGRVVSIVERSLVQMFSGTLTLQRPSGSAKKNERRRQDDEDMKGQPRIVWFKPTDKRVPLIAIPIDQAPEDFVENHASYGHRLFVATIKRWPLSSLHPFGHLERELGNIGNIEIETEALLADNNITTTAFGEKVEKCLPELPWVISEKELSSRRDLRNTCTFTIDPATAKDLDDAVSCNRLEDGTFEVGVHIADVSHFIKVGSALDREAKARATTVYLVQKAIPMLPTVLSEDLCSLRANVERLTYSVFWKMTEDGDILDTSFSKSVIRSCAQLSYDDAQKVITMGSLDPKVEVFNHPRSLVEDSIRTFFKLSLILRQKRFDNGALSINPVKLAFETDEKDTPMDVSVCELKESNRLIEEFMLLANMSVAKQIYGFFPEQSLLRRQEEPLGKRMADFIQNMNKAGLELDASSAGALQASMDAIQDPDIRKVVQLLALKPMHRAKYICSGMLVPAKHQHYALNAPLYTHFTSPIRRYADIIVHRLLEASLTGDSKFYLNKESCQKSANQCNLRKDAAKLAQEQSNHLYLSVLLRNLTEKKGMIVREAIVVQVLDVAFDVMVPEYNLEKRVHLDQLPLERYAWRESTGTLKLFWSTQPFKTQEEGSVVENLSDRRLSTVSQQNMDFKPRAAGFDAMDHPDDATNAYDDERGLFDDDSDYDDDDEPLAKHAGGADQEDDVGDDQAENLSKIKMFSRVQVVITADTTVSPSVIKVVAMNPCADYSDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNC5</accession>
    <name>A0A9P6MNC5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF3020 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_003990</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002090">
        <property type="protein sequence ID" value="KAG0007989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNC5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021386">
        <property type="entry name" value="SPP41_DUF3020"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11223">
        <property type="entry name" value="DUF3020"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3020" evidence="2">
        <location>
            <begin position="62"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0007989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="291" mass="31611" checksum="28CE276181F6DAA2" modified="2023-09-13" version="1">MSTDGTNNAVTHSSQVTITAAPSTDSVVEAAAAAAAVTAAVTESIQDKAKREAISQKIRDENRERKKRWRQQNEDRNKDNDLRCRVNKRANKLLEKADSETKARWIEEEFSKRQAKRKEKERKRNPNATAIAASSATDLDGQLPSVVKPPLTLSEHLALHAVSAVALPTSHQELQHQQLQVTAAALNPANPQFDPNTVKTALALSDLVKKNGSHLDLAQLTGVLSDPNLARQLLELEASTAASAQPAAPMVLMNTTSNPAPEVSKASQMMDTEYPMDAVLTLMQLNGSWKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNI0</accession>
    <name>A0A9P6MNI0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_003874</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002050">
        <property type="protein sequence ID" value="KAG0008087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNI0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0008087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="67" mass="7873" checksum="4E98780757CACC36" modified="2023-09-13" version="1" fragment="single">NWYNSLLRAVMKYMPKSVFVKSLSVMYSYRPQVSFLQPVQDRGMETPAPQPSLVRARAIIERGQWRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPL3</accession>
    <name>A0A9P6MPL3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Translin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_002633</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the translin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001656">
        <property type="protein sequence ID" value="KAG0009205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPL3"/>
    <dbReference type="OrthoDB" id="31005at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14820">
        <property type="entry name" value="TRAX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.190">
        <property type="entry name" value="Translin, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.200">
        <property type="entry name" value="Translin, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016069">
        <property type="entry name" value="Translin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002848">
        <property type="entry name" value="Translin_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016068">
        <property type="entry name" value="Translin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036081">
        <property type="entry name" value="Translin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10741">
        <property type="entry name" value="TRANSLIN AND TRANSLIN ASSOCIATED PROTEIN X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01997">
        <property type="entry name" value="Translin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74784">
        <property type="entry name" value="Translin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="187"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="10"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="191"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="210"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0009205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="423" mass="46141" checksum="88DA613664805DAC" modified="2023-09-13" version="1">MEDVHMGTPPMSSTNNLESPSAVQETENTKDPSRLDAIRANLGQSIVSDFGIYRDILDEHHERRERIIKVSRDINNFSKKMIFSLHRAEPKDYLPQFSASSEALLEFKEKHVTVLKLFHRAAIDLQGSNYYRYQRSISGAMQEYIEAMTLEYYLLHGKLMPKSALEADLVFMTNPEQFNNPDLIIGIGQTQSGGGGGGGGGGGGGSRGKFNKDNRKTPYNKDKREGGTKPGNEPTTHVTPVNPLISANNTTTTATAMEDIHTSTATTSTASQADVQQVKLTKLTLEVTDEDYLLGIADLTGELMRLAINTLGQSLVVSTKDLELEGGLQLPSPEERVQQILSFLRNIKSGFDSLSLTKASPISKKMGVLKQSLNKIEMACYNVKVRGAEYPPDILRQMLMNGPDVGGGSNVGIGGEAGGDDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPP0</accession>
    <name>A0A9P6MPP0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_002443</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001600">
        <property type="protein sequence ID" value="KAG0009399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPP0"/>
    <dbReference type="OrthoDB" id="8922241at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051061">
        <property type="entry name" value="Zinc_finger_trans_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179:SF13">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="291"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="350"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="123"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="216"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="216"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="229"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0009399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="384" mass="42310" checksum="E3C127DE0966FC1E" modified="2023-09-13" version="1">MFATPSQQQQQQQQQQATAQYTLMSGQQPQQGQGSEDMFFALERLLMGISPFPPTIPTLAKPTCPSLDDQIMAEIQATSSPSIPSIVLNEQSLDLLQQYYQNQDNSLQSLQYNNYSGCAIDQSDCSSTSRSASPPNSPYSYSSSLVSSPAMPLASESYWMTPTMPAQQQQQQQQQDWDVSLFDQMNLPLTMAGLENYIAPTATDLLSEPLLASQSLKQATSSSPSSSSKKVKPHHRRTSSNCSAISAYESTARREHRASSISSVCSTASATSNNNNNNTNSNSNVRPIKSYACPTCTKPFPTRTQLKSHMAIHTDSFPFPCMHAGCELHFKRKHDLRRHIDAKHALVKKYLCTGGCGEGFGRRDQMVRHLRRGACGQGQGFQTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQ25</accession>
    <name>A0A9P6MQ25_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">HRK1_1</name>
        <name evidence="12" type="ORF">BGZ80_002984</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JAAAID010001765">
        <property type="protein sequence ID" value="KAG0008860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQ25"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13994">
        <property type="entry name" value="STKc_HAL4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24343">
        <property type="entry name" value="SERINE/THREONINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24343:SF137">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE HRK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 12" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="475"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="139"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="225"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="282"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="358"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="416"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="774"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="44"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="302"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="358"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="380"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="416"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="788"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="504"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0008860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="802" mass="87130" checksum="A5A927E74242FCF8" modified="2023-09-13" version="1">MTDHNNDATTPLEDTTLHPSHLKSPAGSNNAMSFNAADHEHLTSELSTSSIPNIQTPQLSVNKLESPISSAATAQLPTSSPPQIGDTSAPPESIGNNYLNAVELTQAGDRPPLQLGKDSVGTSLANLAKRKLPISPLALSSAIPDEDNTVATSEPSDAPKQHNPTTPNLFVEDTPPQNVQTIEPQARGAGRRSRAVTLEMTPVEIDKVLEDAATRLVIARHEIGGSASSSDVDSPDHSGADHTSTSQARQIPHPNLAHAHFHGLNLSRTSSDATEVIVSHPASVDASRHNSDDEDDDHYQDPVSTQQRQHATSAKPKPNESIQQLSNALEQQKIASLAAPSTPGPSFAYTAVEDTNVTAKASDSRPASPNRHHSITASLRKKEKEIDPSKSSHKKAGKETSHGIFHDLKRFFNVGHSTHVSPSATPVNPSSSESHINSTLKPKRSISGGSHGHGSEHSSGHHGNAIESDLRKKYGKLGKVLGRGAGGTVRILSRSSDHKVFAIKQFRKRRPDESERSYVKKVTSEYCLGSTFHHPNIIETMDIVKESGTYYEVMEFAKYELFTAVMSGLMGREEIACCFKGIVDGVAYLHGLGVAHRDLKLDNCVMNERGIIKIIDFGCSMVFRPPFDKRIQMAKGISGSDPYIAPEVFTSEQYDPRLADIWSMGIIFLCMTLRRFPWRVPRLDQDQSFQAFVNPDGKQRLLKLMPRESRPVMSRILELDPSKRALIGEVLADPWIKSVDHCTTEYMSPNHSHHLGDDGTVAQNPHEGMLALPPSNRGSDSGRSHGITVPTANTATYTTSNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQ75</accession>
    <name>A0A9P6MQ75_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_002866</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001729">
        <property type="protein sequence ID" value="KAG0008967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQ75"/>
    <dbReference type="OrthoDB" id="2426736at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0008967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="147" mass="17134" checksum="81DB1BF14E611B48" modified="2023-09-13" version="1">MSFPKWVYVKTKVPYMGANRDRVLPRPLKEQEVFVVVKFQIPQKLSIGGFRIFTLQRQTVDRRLKKLIADNNKLGSVELKMLRFDPSLRGENAIQHMRRDKDAPIEFNNRSFVLRGNSNIEMIEYITKVFNAYTDDYSEGAVSSESD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQ95</accession>
    <name>A0A9P6MQ95_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Peptide hydrolase</fullName>
            <ecNumber evidence="17">3.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">BGZ80_002099</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">May be involved in vacuolar sorting and osmoregulation.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Endoplasmic reticulum membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Vacuole membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 17">Belongs to the peptidase M28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="17"/>
    <dbReference type="EMBL" id="JAAAID010001508">
        <property type="protein sequence ID" value="KAG0009748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQ95"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03875">
        <property type="entry name" value="M28_Fxna_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.10:FF:000008">
        <property type="entry name" value="Endoplasmic reticulum metallopeptidase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048024">
        <property type="entry name" value="Fxna-like_M28_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053975">
        <property type="entry name" value="PFF1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="METALLOPEPTIDASE M28 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147:SF58">
        <property type="entry name" value="VACUOLAR MEMBRANE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22250">
        <property type="entry name" value="PFF1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="16" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10 17" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="15 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="7 17" id="KW-0645">Protease</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 18" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0926">Vacuole</keyword>
    <keyword evidence="12 17" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="350"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="380"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="420"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="466"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="493"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="526"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="558"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="591"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="19">
        <location>
            <begin position="129"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="Vacuolar membrane protease C-terminal" evidence="20">
        <location>
            <begin position="617"/>
            <end position="836"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU361240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF22250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAG0009748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="853" mass="95087" checksum="1C342A549289A156" modified="2023-09-13" version="1">MVVSYLVIGSIVSYKRLSLPTPKSVADAVNPDDFSADWAWQHLEQFAQMPHPINSRENLRVRDYLVNTVKSLQEEARQLGRIVEIADDNVKLTQARNFLSNATRLEFYESSNIIVRVVGTEGRAENSLKGRAEAVVVDAHFDTVLIGHGATDDGIGVAVCLEMIRNLIHHPVKHNVIFNINNGEEVGLFGAAAFMKHQWAADVKAFVNLEGAGAGGRALLFRSSNKALAKFYSKVGNSPHANVFGNDVFKLGLIKSGTDFSVFTAYEIPGLDIAFYSRRAFYHTLQDDIEHTSRGSMQHMGNTGLTALRNIADSDYLITPKEIVSSESSIYYDVAGLFMLVYSFNTYLTLNYNLIIVVPAFIAWAILASRKNGLTLSVVLRSYFAMLLSFVTAIATSVGFAAALNKINPMLVYGEHWLGFWFFVFQSCTTIILIQWGWVNFELWLKGDFGPLEIALERMRVDSEQVANVAMVLFWWTLLIGATVLGHSKEIGLFYFVTWFVVTSMISAYFSVYPRRRGTPWTLARLWINFLPLMMVLDIAITNMIAMGQTLVDGTPPFAIMALFSLCALNCVMPLIPTIHRSANFRKMGQVSVFLSLVLLVSACVVFPYNAKEAPNKLIWRQIYDLDNDTSFVTVKTMNNLEAIMKMIPSSMNSECSLDPVSGVLTQCVYVGATPKLVADSKVSGKDIIKSEVSKPEHRREKDGNYAEEISVEENTSEDSKNLLRTVHLKWTAQDSRLCQVSFPINDSIVFLKLDGFDEPEQGYNSSAVISASKAGMIGFKRKYDQVWDLKVVYKVESTDAPALEGTLGCLYDEWDREQIPAFTDMKNHLPSWALLGGGKGPGLLTIQKKILV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRJ4</accession>
    <name>A0A9P6MRJ4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">Phospholipid-transporting ATPase</fullName>
            <ecNumber evidence="19">7.6.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="24" type="primary">NEO1</name>
        <name evidence="24" type="ORF">BGZ80_001649</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="24" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="24">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14 19">
            <text>ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.</text>
            <dbReference type="EC" id="7.6.2.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out) + ATP + H2O = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66132"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="15">
            <dbReference type="Rhea" id="RHEA:66133"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 18">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endosome membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="19">Membrane</location>
            <topology evidence="19">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 19">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="24">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.6.2.1" evidence="19"/>
    <dbReference type="EMBL" id="JAAAID010001380">
        <property type="protein sequence ID" value="KAG0010253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRJ4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140326">
        <property type="term" value="F:ATPase-coupled intramembrane lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045332">
        <property type="term" value="P:phospholipid translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07541">
        <property type="entry name" value="P-type_ATPase_APLT_Neo1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000085">
        <property type="entry name" value="Phospholipid-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000009">
        <property type="entry name" value="Phospholipid-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006539">
        <property type="entry name" value="P-type_ATPase_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032631">
        <property type="entry name" value="P-type_ATPase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032630">
        <property type="entry name" value="P_typ_ATPase_c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01652">
        <property type="entry name" value="ATPase-Plipid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092:SF5">
        <property type="entry name" value="PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092">
        <property type="entry name" value="PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16212">
        <property type="entry name" value="PhoLip_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16209">
        <property type="entry name" value="PhoLip_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 17 19" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="9 18 19" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 18" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 17 19" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 19" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 19" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="258"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="292"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="497"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="521"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="1033"/>
            <end position="1053"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="1059"/>
            <end position="1081"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="1111"/>
            <end position="1131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="1137"/>
            <end position="1154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="1166"/>
            <end position="1187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="1199"/>
            <end position="1217"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase N-terminal" evidence="22">
        <location>
            <begin position="240"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="21">
        <location>
            <begin position="338"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase C-terminal" evidence="23">
        <location>
            <begin position="999"/>
            <end position="1226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="1"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="36"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="119"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="182"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="active site" description="4-aspartylphosphate intermediate" evidence="16">
        <location>
            <position position="585"/>
        </location>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="585"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="585"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="586"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="587"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="587"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="688"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="730"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="754"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="783"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="864"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="865"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="866"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="946"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="952"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="972"/>
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        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
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        <location>
            <position position="975"/>
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        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
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            <position position="976"/>
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            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
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            <position position="976"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00034036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="RuleBase" id="RU362033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF16209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="Pfam" id="PF16212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="KAG0010253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1234" mass="137322" checksum="2E15836D5613025A" modified="2023-09-13" version="1">MSKGKETFALLPLNNNHYENENDSDNDNNATESTSFTSNSRTISINRDGTRTTRTSAVHSHNNRTDSPRPRSPPDNNNSHTSQPSTPRGNHYPKHLAFSLPASNASDGARGYGEGFTPTTSTSSSTNNSSNNNQNSARSGMPLGLGSSSNGGGGSASHGYRHSKYKYSDEEDEDEEPLLLHSSTSFTGGSSSGATRGDNSSSPQGKGPNRQKLSAIMNELKPSKDSKAAKSRTIDFHASAKEKNRYPPNVTRNTKYSIISFLPVVLWEQFKFFLNLYFLLVALSQFVPALKIGYIVTYVAPLCFVLAVTIGKEAVDDMKRYRRDQEANSQRYQKLTPSGFKMVPSSKIKVGDMIVVNKNQNVPADMVLLRTTEASGACFIRTDQLDGETDWKLRLAVPSCQALPSDESLLELNGFIYADSPHKDIHSFIGNFSKEGDGPGQHTEPLSVDNTLWTNTVVASGNAIGFVVYTGRDTRAVMNTNHPKTKIGLLDSEVNRLSKILCAFTLTLSLSMIALNGFEGLWYIYLFRFLILFSSIIPISLRVNLDMGKTVYGWQIMNDKEIPGTIVRTSTIPEELGRIEYLLSDKTGTLTKNDMELKKLHMGTMSYSVDTMDEISTHLDTAYSQHSSGFNRSRGIATAPAHVGGNKARRDISSRVRDIVQALALCHNVTPVEEDNGSITYQASSPDEVAIVKWTESVGLTLVFRDINNIHVRNAHGDIFEFEILQVFPFTSETKRMGIIVRDLTTGEITFLEKGADVVMTKIVQYNDWLEEECGNMAREGLRTLVVARKRLSEELYQEFEAKYHVAKTSISDRTNAMNAVVNQVLEQDLELLGLTGVEDKLQDGVKTTLELLRNAGLKIWMLTGDKIETATCIAISSKLVARNQSIHQIAKLKNPLDAQDELDLLRSKKDCCLVIDGESIQLCLDHLREEFIEITVRLPVVVCCRCSPTQKADIARLIKTYTKKRICCIGDGGNDVSMIQQADVGVGIVGKEGKQASLAADFSVNQFSYLTKLLLWHGRNSYKRSAKLSQFVIHRGLIISIIQAVFSAMFYFAPIALYQGMLIVGYTTIYTNAPVFSLVLDQDVSEDIALLYPELYRDLTKGRSLSYKTFFSWLLISVYQGGAIMILSIWLFENQFVNIVSISFTALVLNELLMVALEINTWHRLMIVSEVATLFIYIGSMVFLPTYFDLNFILTRTFLWKVAVITMVSSFPLYVIKMLRRKFAPPSYSKLTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRJ9</accession>
    <name>A0A9P6MRJ9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 10">Man(5)GlcNAc(2)-PP-dolichol translocation protein RFT1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">RFT1</name>
        <name evidence="12" type="ORF">BGZ80_001068</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Intramembrane glycolipid transporter that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. RFT1 could mediate the translocation of the cytosolically oriented intermediate DolPP-GlcNAc2Man5, produced by ALG11, into the ER lumen where dolichol-linked oligosaccharides assembly continues. However, the intramembrane lipid transporter activity could not be confirmed in vitro.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Endoplasmic reticulum membrane</location>
            <topology evidence="1 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the RFT1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001237">
        <property type="protein sequence ID" value="KAG0010939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRJ9"/>
    <dbReference type="OrthoDB" id="9979195at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006488">
        <property type="term" value="P:dolichol-linked oligosaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034203">
        <property type="term" value="P:glycolipid translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007594">
        <property type="entry name" value="RFT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13117">
        <property type="entry name" value="ENDOPLASMIC RETICULUM MULTISPAN TRANSMEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13117:SF5">
        <property type="entry name" value="PROTEIN RFT1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04506">
        <property type="entry name" value="Rft-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="155"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="194"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="224"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="262"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="469"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="512"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="546"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="573"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="620"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="660"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="424"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="432"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00045912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0010939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="696" mass="76740" checksum="3B2F39950E8C427D" modified="2023-09-13" version="1">MESSEPVLKQRSASATTASSSKHSDSVSNETNSNVDVKSTDQTSSILSSSVQGASYLVLLQFVSRMLTFSLNQVLLRFTSAETLGIASVQLELLLNTILFLSREGVRCAAIRVSDDPDTATEPEPKTTEKDEKISIATLRPGTEAYKLQKFVNMVYAPIPVGALMTILAVGYFLSQVDKSSESEYPGYRLSIYLYGLSALIELLAEPMFMVAQYRLWVRTRVSVEGTAVLVRCLLTCALTVYGARSTVMGSSSTSNKNTMGVLAFAIAQFVYGLLILGGFLMAFWSKSTERRKHDRQRVAAAEMKYLGHKSPHIAEEKEDQIDDFVSLKALLPRKLIRVDKDGKSEYFYFDTHLLKLSKTLTAQSLLKHILTEGDKMLMARFTGPSAQGEYAFVVNYGSLIARILFQPMEEISRTLFSRLLSDVGPASSPETSSIEKTSSGSTTTTTTTANIHNVTETQRANLLLSRNLLLTIMKFHVLLGSIFIAFGTHYTATLIDLVVGQKWSRNTNAPAVLSLYCWYVPIMGINGITEAVVQAVASEKELGILSYWMIGFSAVFCSTGAFLMGVMDLGAIGIVLANCVNLSVRIIWSMWFLSGYYGRYIPAGSGAGSSPSKHSRFSYVPWGNIIPRPMVLAAFGAAYMVTSASEQWIGWDRFHDKMVHLGIGALTFAVVMGVIFVIEKQFIRDIRDVVKQRRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRS6</accession>
    <name>A0A9P6MRS6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BGZ80_001362</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JAAAID010001305">
        <property type="protein sequence ID" value="KAG0010585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRS6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007010">
        <property type="term" value="P:cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000354">
        <property type="entry name" value="AGC/YANK protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000024">
        <property type="entry name" value="Probable serine/threonine-protein kinase cot-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050236">
        <property type="entry name" value="Ser_Thr_kinase_AGC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356:SF422">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="38"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="418"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="625"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="662"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="340"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="7"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="439"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="452"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="546"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="634"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="670"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="698"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0010585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="698" mass="78587" checksum="1787DF1E5AAAF19C" modified="2023-09-13" version="1" fragment="single">MGNGSSRDQEDAFDNEGKSSSHAFKSDAGFKRFNLFQFKFLRVIGKGSFGKVRMVERRETGKVYALKYISKEQVIKMEAVRNILRERQILESVDHTFVVNMRFAFQDDEYMYMCMDLMMGGDLRFHMNRRNFAEDVVRYWIAETSSAVAYLHSLGIVHRDIKPDNILLDEKGHAHITDFNISCKLTPEKPFLTSQSGTVAYMAPEVFKGTGYGTSVDWWALGVIFYECIYNQRPFLTENIGELKRAITNQTIEYPHKETISQEDPAERLGVRGVGGIDEIRLQPFFRVAANQAGMSPDQWWHMLETKQLTPKFQPPAEAANFDATYDLEELLLDEDPLSYRSTRERAQRLRREKNEAIKQENARRKAEHDAAIAAEKEAQAAMEAMNRELEQSMRKINSPRLSSSSILSKKKSVLHLFGGDSGNKNSIGCEDSRQPAPQTQPPSAPPHQSPNSHTLSQLSRQTQFQSIPLSPIDSTANGNRELPPSPLPTLRFPPATTTLDQSSSHYHYPPTPPKILNSTAAGRDTSESKAGLFPMDKNLMDDNNDSTRSRRRDSGQSSKDIIGVQALPPPSPLMPSAMSDRQLSQEHLAAALPQQQQHPFQAAHPQMAISSPVIIPTPLDHSVSRHKHIPTQQPQPQPQPPGRYQPGYSIMADIDEPMEVDSQASTVDTKGKAKADKDSGKKRFEVKKWNAVALWAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSE3</accession>
    <name>A0A9P6MSE3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome b-c1 complex subunit 7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">QCR7_1</name>
        <name evidence="10" type="ORF">BGZ80_000804</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the UQCRB/QCR7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001177">
        <property type="protein sequence ID" value="KAG0011275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSE3"/>
    <dbReference type="OrthoDB" id="425749at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045275">
        <property type="term" value="C:respiratory chain complex III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006122">
        <property type="term" value="P:mitochondrial electron transport, ubiquinol to cytochrome c"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1090.10:FF:000001">
        <property type="entry name" value="Cytochrome b-c1 complex subunit 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1090.10">
        <property type="entry name" value="Cytochrome b-c1 complex subunit 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003197">
        <property type="entry name" value="QCR7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036544">
        <property type="entry name" value="QCR7_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12022:SF0">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12022">
        <property type="entry name" value="UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX 14 KD PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02271">
        <property type="entry name" value="UCR_14kD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000022">
        <property type="entry name" value="Bc1_14K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81524">
        <property type="entry name" value="14 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR000022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0011275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="123" mass="14101" checksum="6789E8DA3B1DE112" modified="2023-09-13" version="1">MSGITFVNQVKASKFLSGMLQPVANAFVNAAGYRQLGLRYDDVLREETDIIREAINRLPEQEGYERVFRMKTAFQYSLSHTIATKENALKPEDDIRYLTPIIDEVAAEYAEKEDFNNIKSFSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSV1</accession>
    <name>A0A9P6MSV1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ADP-ribosylation factor-like protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ARL2</name>
        <name evidence="10" type="ORF">BGZ80_000719</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the small GTPase superfamily. Arf family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001157">
        <property type="protein sequence ID" value="KAG0011391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSV1"/>
    <dbReference type="OrthoDB" id="2011769at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04154">
        <property type="entry name" value="Arl2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000393">
        <property type="entry name" value="ADP-ribosylation factor-like 2, arl2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045873">
        <property type="entry name" value="Arl2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044612">
        <property type="entry name" value="ARL2/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45697">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00328">
        <property type="entry name" value="SAR1GTPBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0519">Myristate</keyword>
    <keyword evidence="3 7 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="23"/>
            <end position="30"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="125"/>
            <end position="128"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00026198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0011391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="184" mass="20855" checksum="4BA0E6466381C834" modified="2023-09-13" version="1">MGLLTILKKNRQKEKEIRLLILGLDNAGKTTILKRINGEDIDTISPTLGFNIKTLEHKGFKMNIWDVGGQKSIRSYWRNYFEQTDGLVWVVDSADRLRLEDCKKELHELLQEERLSGASLLVFANKQDLPGALSDDQIREALALDEIVTHHWAILACSAKTGSHLLKGMDWIVGDIGSRIYLLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSZ9</accession>
    <name>A0A9P6MSZ9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BGZ80_000361</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001072">
        <property type="protein sequence ID" value="KAG0011884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18597">
        <property type="entry name" value="ABC_6TM_YOR1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000006">
        <property type="entry name" value="ATP-binding cassette, sub-family C (CFTR/MRP), member 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000997">
        <property type="entry name" value="Multidrug resistance-associated protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000163">
        <property type="entry name" value="Multidrug resistance-associated protein member 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF456">
        <property type="entry name" value="MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN LETHAL(2)03659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="235"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="263"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="341"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="794"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="834"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="934"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="128"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="473"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="814"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="1032"/>
            <end position="1266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0011884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1304" mass="145114" checksum="3D656A9383AE2BBA" modified="2023-09-13" version="1">MSEKKPHSSTHDPTISDIPDKDKDDDGMYTIFKKGPVSPENFAWLPSRIFLWWLNGFFAKGYKKRIDEDDLYEMLDCNKSSVLADNVAKRWEAEQARAARKGKAPSLIRAMIMAFWDRYYTCIIGMECGDACQISNPLLLQRVITFVNNSATANPPPAWHGYGYAVAMVFLTLWQNVCYQRWNLGSVTMGIYIRASLIDLVFRKATKLSSRAHLIYPDGAIVNLMSTDASRIDTAMLSMMIVVSVPIYTCVVIGLLIHLMGPSALLGAAMLVLANPIQAWAMSRLAPIRKRASQFTDARIRLTQEVLQGIKVIKFFSWESQFLKKLSDIRENELKNVARLLYVRGAVAATSASLPVFASALSFILYGAIGNELNAEIVFPALAYFTVLRTPLMVLPSAYTVTVDAYVAMKRIEAFLLSEEADPIPPPDPSHEYALSMNDASFIWDQLPDSNGSTETLISSNIESNMSEMTETAKGDDAQHQEPTKPTYLTKLNLHIPRGSLVAIVGPVGSGKSSLLQAMIGNMTQTEGEIIRGTNISYASQTAWIQNATIQNNILFDTPLDEERYNRVVKACCLEADLKLFPHGDQTEIGERGVNLSGGQKARLSLARSVYFNAGTVIMDDPLSAVDAHVGKRLWQDCILNELKDRTRIIATHQLHVLPDTDYVICMRNGVIAEEGTFKDLMEKNGDFCALMAQYGGVQAEEKENTDITFDDIKPDTIDEEEPLKSSAFSIGEESTATVVKEKDGVYKDGLGDEDRKSLEAKAESPHKLMSEEERESGAVKGDVYGGYLKAAGWYFWFITFGLFFLQQAANVVFSRDVDTLDNVLWSTLYEFTITVVTLMGTLVLIIIVFPWLVLAIVPILCLYYALSIYYRTTSREVKRLDSNMRSYLYAYFSECLTGLGTLKAYNVVNMAILKNEYRIDLNNRPYYMYQVGARWLSIRVNVLGALMLFSTVVMITATRFKINPASAGLVLSYLARISGDLNWGVQRFSTLENNMNSAERLVHYVENLAQERPPEKPENKPPASWPSEGRIDFKNVSMRYRPELPRVLRNISFEVQPGHKIGVVGRTGAGKSSLIQALFLLSELDEGQVVIDGIDTNTLGTADLRPKIAIIPQDPVLFQGTFRYNLDPLSRHTEQELWQVLETSDLKSYVQSQEGGLDAMVSAQGENLSVGQRQLVCLSRALLAKSKVVVLDEATASVDMATDSLIQKAIRIDFAHSTVITVAHRINTIIDYDRILVMHQGQVAEYDTPRNLLSNPNSVFSSMVAETGAQNASHLRSLAGLNSAIPPIYDGKGVLVPYPPSHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTW7</accession>
    <name>A0A9P6MTW7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_011593</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000951">
        <property type="protein sequence ID" value="KAG0012669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTW7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="69"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="321"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="460"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="530"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="558"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="145"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="432"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="14"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="327"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="460"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="479"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="494"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="508"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="564"/>
            <end position="586"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0012669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="635" mass="70315" checksum="AC3CD8A0EAD62B39" modified="2023-09-13" version="1">MLGSHAAVTNHSHQFNQQTQFNQQEEQQDAMAALKAAVSASFFTTNNHTTDDSTNMKRTRVLSTNVNATEIKSLSPPPPPANNTHSSALPSRMDESNRSNSHSHVNQHRLSELPTPPPASTHPPSTSAVFPGLSSRPSSAVLDRCEALESEAEATSSRVRLEEKEKENQQLKSQVQKLTSELREANLDRDSLSLEMAECHSDNAKFLKRLRTSNDKVDGLQDENRYLIEQLRELRAKVTDISGKKSRLSESLDRERHRASQVALELEGVVARYKREVERLQDLVLALGHKQVQVQSQLAYFQQQHQQQQAQDQKLPANFTDSLIDGQDQSPNGNNTLSTGPNVLSTATDASISLKAAASSSSTTTTDSPLQQQRYGDLALGDGALASILSSVAASSNSRRSKPARRFTINASHQEAPLTLEQRKSKLLMDQITVLQRGYDTLREEKATLELQLEMMQRQHLYHQHRHNRRNSQRKALGPDQHQQQPSQEQDSQTGNNTRPSATGDVSINDRKAAETKQDRDFKIQETLASLESKTGQGGGRKAQVTSPHRLQHVENDTEASGDLAPTSSLSSATSLGSLSSSTSSANDKFPQRLYTQKMLHPSRPHQHGSISRVISHHEWDVQQCSCCMGALIEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MU44</accession>
    <name>A0A9P6MU44_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Gamma-soluble NSF attachment protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">N-ethylmaleimide-sensitive factor attachment protein gamma</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_011495</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNAP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000930">
        <property type="protein sequence ID" value="KAG0012813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MU44"/>
    <dbReference type="OrthoDB" id="9984275at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005483">
        <property type="term" value="F:soluble NSF attachment protein activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019905">
        <property type="term" value="F:syntaxin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000744">
        <property type="entry name" value="NSF_attach"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13768:SF2">
        <property type="entry name" value="GAMMA-SOLUBLE NSF ATTACHMENT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13768">
        <property type="entry name" value="SOLUBLE NSF ATTACHMENT PROTEIN SNAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14938">
        <property type="entry name" value="SNAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="289"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="322"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="340"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="393"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="404"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="443"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00040047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00042485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0012813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="453" mass="49921" checksum="272AD44DF272C5DC" modified="2023-09-13" version="1">MAALDEARLKDAIKFMHEADKNTEKSWFKKPDWDIAAQYYEKAAQSFKAGKSYEQSVQAFIKASDAMINAHSLFMAGRALENGANVCLQNLGQPERAADMYKRASELFIQNMTPDRAAEMLEKGAKAMEPISVDSAIDFYVNACNIYENEERAKYATDTYKRTINLLVRNRRFEKATDILLRLGNVQSEAANKSAYFKTLLSIVIIQLAAGDEVEAGKKFQEFCGIDGFVRSEESAVAHAMLDAFEHGDQNYYNQAAARQHVGFLDNEIARLARNIVISNDLISEGGYVNPSGPGGNGQFSQPGPGGPGRPSGGPYADNRNKNNNGGNFNNSGYQQPPSQQHHGPAPPYQQYQGQAPPQPQLGHYQEKPMPPEPQGYNTTPRAGGPPPAPAHLQDERSESDWRALTGAPAGPTPAPVQQQYPQRHQQQQQQQPGAPPSRNYYQDEDDDDGGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MU83</accession>
    <name>A0A9P6MU83_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_011194</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the alpha-ketoglutarate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000871">
        <property type="protein sequence ID" value="KAG0013262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MU83"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016624">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006091">
        <property type="term" value="P:generation of precursor metabolites and energy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02016">
        <property type="entry name" value="TPP_E1_OGDC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1150">
        <property type="entry name" value="TPP helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011603">
        <property type="entry name" value="2oxoglutarate_DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23152:SF4">
        <property type="entry name" value="2-OXOADIPATE DEHYDROGENASE COMPLEX COMPONENT E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23152">
        <property type="entry name" value="2-OXOGLUTARATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000157">
        <property type="entry name" value="Oxoglu_dh_E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="Dehydrogenase E1 component" evidence="5">
        <location>
            <begin position="236"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="domain" description="Transketolase-like pyrimidine-binding" evidence="6">
        <location>
            <begin position="623"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0013262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="738" mass="82107" checksum="0860C6BF280D641C" modified="2023-09-13" version="1" fragment="single">MSGILRLAAANTSRAIPKSSFGLIRSAGIHRHALQQPIKPIQSRATAASRSPIGQASKTLLPGVHAIQRRQYHDDGAYGYRVPKVFSMPDYTPEELANRVENANLLRLVIGYRTHGHRNANLDPLGIVKREFVPALSAERYELTDPSKVYNLSGILHVNQSKSSTDAKDEATLKTIIAHLEKSYCGNIAYEFVHIPNASERRWFAHQVESYQKPPITPEDKKRIFELLTKSEVFDHFMGKKFAQVKRYGLEGAESMMVALDALFQGASKAGVTEAVLGMPHRGRLNLLTDLLQYNPTALFSKVKGNPEFPSDLPATGDVLSHIANSPKIDYGEAEPIHVSMLHNPSHLEAVNPVAMGKARAKQMDLIANSSPECQLGDKVMCVQLHGDAAFTGQGVVMESLGLSNLPHFSSGGSVHIVVNNQIGYTTPAQNARSSVYSSDIGKMINAPVIHVNGDHPEEVVHAMKIAFEYRNKFRKDVILDLIAYRRWGHNELDEPAFTQPLMYNNIRSRKSVPKMYEEKLLAEGILDKAAIDEFRQDYFEKLDDDFAEIESFKPEADHLKGKWKDMILPTETVSRIETGIDKETMKKIGAASVTVPSDFVVHPRLEKFHIQSRLNKLKDGQKIDWATAEGIAFGSLLMEGYDVRICGQDVGRGTFSQRHAMFVDQKTERVHIPLNAMSESQGHLEVANSSLSELAVLGFETGMSYETPRMLNIWEAQFGDFFNSAQVTIDTYVASAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUH2</accession>
    <name>A0A9P6MUH2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_011413</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000915">
        <property type="protein sequence ID" value="KAG0012926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUH2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0012926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="217" mass="24410" checksum="E74BD555900A685B" modified="2023-09-13" version="1">MQRRFKTYKSAYNDACRIKKRTGSGVTDEDIARGNNTIEEVLEWKCYGFKRMKELYEKHSSSEPTCAADFSTQGIRILSSGNEQDESHEAEEYEVDEFLEMDELDESYECGDGDDLHQWELPVHTTQSTAQSFSKDAALWTETRSQPRAPSSTVTPLSKTSSYERSSSRKASSPRMSFPVPVVPVIPGKIQKVSFGASLVQASEARAKESRARTTIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUJ5</accession>
    <name>A0A9P6MUJ5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ribosome assembly protein 1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Elongation factor-like 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">RIA1</name>
        <name evidence="12" type="ORF">BGZ80_011501</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000931">
        <property type="protein sequence ID" value="KAG0012811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUJ5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042256">
        <property type="term" value="P:cytosolic ribosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01681">
        <property type="entry name" value="aeEF2_snRNP_like_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04096">
        <property type="entry name" value="eEF2_snRNP_like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01885">
        <property type="entry name" value="EF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16268">
        <property type="entry name" value="EF2_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16261">
        <property type="entry name" value="EF2_snRNP_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.240:FF:000006">
        <property type="entry name" value="Elongation factor like GTPase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1430.10:FF:000002">
        <property type="entry name" value="Elongation factor like GTPase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000746">
        <property type="entry name" value="Ribosome assembly protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.870:FF:000002">
        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.870">
        <property type="entry name" value="Elongation Factor G (Translational Gtpase), domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1430.10">
        <property type="entry name" value="Yeast translation eEF2 (G' domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056752">
        <property type="entry name" value="EFL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908:SF3">
        <property type="entry name" value="ELONGATION FACTOR-LIKE GTPASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908">
        <property type="entry name" value="TRANSLATION ELONGATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25118">
        <property type="entry name" value="EFL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Tr-type G" evidence="11">
        <location>
            <begin position="17"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="779"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="783"/>
            <end position="793"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00068031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00081809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0012811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1091" mass="120218" checksum="36B77EE1F81255A3" modified="2023-09-13" version="1">MPSIPESELIRLQANQANVRNICILAHVDHGKTTLSDSLLASNGIISSKLAGKVRFLDSREDEQERGITMESSAISLYFKIVRRAATNAAAAAAAAAPASGSVVTDQTKKSVAEEYLINLIDSPGHVDFSGEVSTASKLCDGGLVLVDAVEGVCTQTHTVLRQAWKESVRPVLVINKIDRLVTELQFTPSEAYTHLNKILEQVNAVMGTFFSENVLEEDYRKKAEEQEGKEDSSSTGLEDTFADWHVETQDDSHIYFHPSQGNVIFASAIDGWAFRVDQFAAIYAQKLGMKEGVLRQCLWGDFYLDPKTKRVIGYKGLKGRALKPLAVQMVLDNIWKVYEVVVIEPDREVTEKVVKSLNLKVLPRDLRSKDTRATLTTIFSQWLPLSTCVLLAVVEQLPSPPAAQKIRIPKMLHPFETTPSEPTEDWERGMVNCDISSGVVGYVSKMVSVPLEVLPKNKRKVLTAEEMRQRGKIQREQLIASAKAASVGESGVHLDVDEVIANRAHAEAEEKAVAEELNGKEALIGFARIYSGTIRVGQKLKVLGPKYDPEHPELYCSEVTVDSLFMIMGRDLIGLEEVPAGNVFGIGGLEGHILKYGTLWSADYEGGQNLVRQGLEAAPIVRVALEPEDPSQMQQLIRGLQLLNQADPAVQVLTQETGEHVILTSGEVHLQRCMADLRERFAKIEISMSEPIVPFRETAIDAPAQLVTSSAMSANEINQAQGEKLIAKSGGGARGTIVATTPNRHVRFVVRTVPIPEDLKKYLVDHGEQIQAYVESSLATNSGSKGPSSPSSLPAALHNAEEETKLQEKLMSELKPLFAKAGDDWKGKEKDILAFGPRRIGPNLLINDLGIEFSRNRSNKNQDSEENIITVQDLAESVHTGFQIATNGGPLCSEPMLGMAFFVKEVEILENGQEGGASAEGRSKMAVTSGQVITTMRDACRLGFLEWSPRLMLAMYSCDIQTTAEVLGKVYAVIARRKGKILHEEMKEGTPFFSIQALLPVVESFGFSDDIRKRSSGAASPQLIFSHFEVLDMDPFWVPNTVEELEDLGEKADRENVAKKYMDAVRKRKGLFVEQKIVEHAEKQRTLRKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MV78</accession>
    <name>A0A9P6MV78_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Mannosylglycerate hydrolase MGH1-like glycoside hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_011030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000838">
        <property type="protein sequence ID" value="KAG0013496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MV78"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004573">
        <property type="term" value="F:Glc3Man9GlcNAc2 oligosaccharide glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009311">
        <property type="term" value="P:oligosaccharide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004888">
        <property type="entry name" value="Glycoside_hydrolase_63"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054491">
        <property type="entry name" value="MGH1-like_GH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10412:SF10">
        <property type="entry name" value="GLYCOSYL HYDROLASE FAMILY 63 C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10412">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22422">
        <property type="entry name" value="MGH1-like_GH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mannosylglycerate hydrolase MGH1-like glycoside hydrolase" evidence="1">
        <location>
            <begin position="442"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="domain" description="Mannosylglycerate hydrolase MGH1-like glycoside hydrolase" evidence="1">
        <location>
            <begin position="714"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF22422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0013496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="880" mass="102558" checksum="3312D7D3C3318F78" modified="2023-09-13" version="1" fragment="single">MKKGTKVIAADSSAEMKRLTQSHEHKKHWARWGPYLSERQWVREDYSADGDAWRFFPHEHARSRTYRWGEDGLAGLSDNHQRLCFSLVLWNGKDKILKERLFGLTNHEGNHGEDVKELYYYLESTPTHSYMKYLYKYPQAEFPYDQLVSESARRSRNEPEYELLDTGIFNEDKYFDVFVEYAKDGEDVDDVLIKITVHNRGPQDAPLHIIPQFWFRNTWSWFPEGEVQIPSLKKTGSVTIEAKHETLGDRWIHFEAGPKGAPEGPELIFTNNETNIQKLFCQPNKSDHVKDAFHEYVIGGNKGAINTKDHQGTKAAGVYKFDTVPAGGRVEVRVRMNRKRCGKEGVVQKEFEKVFKDRIKDLEEFYGNLAIADLPDDVSSIQRQALAGMLWSKQWYCFDQRAWRKGDPAGPPPPPERRDLRNKEWRHVYIDNILSMPDKWEYPFFAAWDMAFHAIPLSLVDPGFAKSQLDLLTREWYMHPSGQIPAYEWNFSDVNPPVHAWATLQVFRTEDRLFGKQDFLFLERVFQKLLLNFTWWVNRKDTQGNNVFEGGFLGLDNIGLFNRSEPLPNGATLRQADGTSWMAFFSLCMLHISLELAKRNPAYEDIASKFLEHFFHISDAMTYHAHGEEMSLWDSEDNFFYDSISWPGGHTQRLKTRSLVGIIPLFSVLSLDPEYLELFPGFTRRLEWFLNYREKNRPNNVFKKEDTKENGSFLLALVDQTMLRQVLKRVLDENEFLSPFGIRSLSKFHKENPLCMWMNNQEFRVDYLPAESDSGMFGGNSNWRGPIWFPTTYLVVASLKRFHYFYGSDFKVECPTGSGIMMNLEEVAWDIEIRLLALVRRDSQGKRPSNGGNEKADKDPYFKDLIPFYEYFDAETGKGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVA7</accession>
    <name>A0A9P6MVA7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_010636</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000760">
        <property type="protein sequence ID" value="KAG0014134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVA7"/>
    <dbReference type="OrthoDB" id="2387403at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0014134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="83" mass="9848" checksum="A75DF4B540FB7344" modified="2023-09-13" version="1" fragment="single">PCLRNLTKFGGNYKKVTEENFESYVLCNSKTLTKNEDVYFAKNFNYKKNGFTDKEWTVFRNRTVPGFRRALHNCRGGCRKIHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVI7</accession>
    <name>A0A9P6MVI7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">choline-phosphate cytidylyltransferase</fullName>
            <ecNumber evidence="10">2.7.7.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">PCT1</name>
        <name evidence="13" type="ORF">BGZ80_010091</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="9">Phospholipid metabolism; phosphatidylcholine biosynthesis; phosphatidylcholine from phosphocholine: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytidylyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.15" evidence="10"/>
    <dbReference type="EMBL" id="JAAAID010000667">
        <property type="protein sequence ID" value="KAG0015026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVI7"/>
    <dbReference type="OrthoDB" id="17102at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004105">
        <property type="term" value="F:choline-phosphate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031210">
        <property type="term" value="F:phosphatidylcholine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02174">
        <property type="entry name" value="CCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000016">
        <property type="entry name" value="Putative choline-phosphate cytidylyltransferase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041723">
        <property type="entry name" value="CCT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045049">
        <property type="entry name" value="Pcy1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10739:SF13">
        <property type="entry name" value="CHOLINE-PHOSPHATE CYTIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10739">
        <property type="entry name" value="CYTIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5 13" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="7" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cytidyltransferase-like" evidence="12">
        <location>
            <begin position="114"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="352"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="17"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="353"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="395"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00026101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0015026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="421" mass="47736" checksum="2519DC9FACE1570D" modified="2023-09-13" version="1">MSSKRKRSDAASATSKNTNADASMNKQPRISQKSTSTKNKNSRRRAQEEAEDEENKVDVEQERNDQDEDMSKDEAKDSTPKSESSATSVSSSSTKPKYSYPINPPPEGRPVRIYCDGIYDLFHFGHAKALEQAKKAFPEVYLLVGVCDDTMTHSRKGKTVMTDKERYESVRHCKWVDEVIEAAPWVVDQAFLDKHKIDYVAHDDIPYKSVDSDDVYAFVKNQGYFLPTQRTDGVSTSDLITRIVKDYDQYLRRNLERGVTAKELGIGFFKEQEVKFKKSAQDIRASIRQNWHGTKDELKNEISVLRNDLRQTMNMWEDKSQEIIKDFSKLFGADSVVNKIFRRRRRGVDNLITDGSLSGTSNTSSRVASPEGSDLEDGSTSPFGIGREFFRFGRNSSNNSESGMQRSRSISSVDSNDEQSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MW18</accession>
    <name>A0A9P6MW18_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phospholipid/glycerol acyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_009729</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GPAT/DAPAT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000609">
        <property type="protein sequence ID" value="KAG0015631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MW18"/>
    <dbReference type="OrthoDB" id="10255570at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004366">
        <property type="term" value="F:glycerol-3-phosphate O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006072">
        <property type="term" value="P:glycerol-3-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019432">
        <property type="term" value="P:triglyceride biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07993">
        <property type="entry name" value="LPLAT_DHAPAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022284">
        <property type="entry name" value="GPAT/DHAPAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045520">
        <property type="entry name" value="GPAT/DHAPAT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041728">
        <property type="entry name" value="GPAT/DHAPAT_LPLAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12563:SF17">
        <property type="entry name" value="DIHYDROXYACETONE PHOSPHATE ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12563">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19277">
        <property type="entry name" value="GPAT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69593">
        <property type="entry name" value="Glycerol-3-phosphate (1)-acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phospholipid/glycerol acyltransferase" evidence="7">
        <location>
            <begin position="254"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="828"/>
            <end position="849"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0015631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="849" mass="95917" checksum="1866942F8DE5679D" modified="2023-09-13" version="1">MATNNNDSNINTIGKSGAEQSPASVSLELKPLKNIIPIVPAQQVETNLRTSNSSAELIPVLGADNDESGVENLTKKHAGRIREDPVGFVVQTAAFYQGTGWRSYSTYVGTRILYEGFADSFKTRILMSPRVSELIKNMAAKQLEVLVKQRQDVYEAEIATNAGKKNYKPKTRPMRPAEIEARRKTLEDELTAVAKTNIDKLVANMTSMKFIRFFAFLINNILVRMYHQGIHIKESEFLELRRVAEYCAEKKYSMIVLPCHKSHIDYLVISYIFFRMGLALPHIAAGDNLNMPIVGNALKGAGAFFIRRTWADDQLYTNIVQEYVQELLEGGFNIECFIEGTRSRTGKLLPPKLGVLKIIMEAMLSDRVKDCYIVPISIGYDKVIETETYINELLGIPKEKESLWGLLTNSRLLQLKMGRIDVRFAKPYSLRDFMNNEIARREIVNEREKTQNAAKSQLLKALGYKVLADINSVSVVMPTALVGTVILTLRGRGVGRSELIRRVEWLKREILSKGGRVANFSGMETGEVVDRALGVLKDLVAVQKNLIEPVFYAVKRFELSFYRNQLIHLFVHEAIVAVTMYTRIKIGGAKSTQRISYTDLLNEVTFLSRLLKTEFIYNPGDIESNLEHTLAYLKKSNVIDIDSEGYVSLSDVERSIGRENYDFYCFLLWPFVETYWLAAVSLYTLIPTVKELIPPADVNGEPQPYWIEERVSMEKTQMFGKTLYYQGDLSYFESVNMETLKNGFNRLSDYGIMMVKKATNSKEKTKVALHPDFTPSRGADGRLSCNGTLWDMVEHIGTFRREGKNRRDNATVSSRVLRFAEIVANAPTPVKVPLPSPAPKKNGDGAPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MW48</accession>
    <name>A0A9P6MW48_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">Chromodomain helicase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BGZ80_009936</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF2/RAD54 helicase family. SWR1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000640">
        <property type="protein sequence ID" value="KAG0015312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140658">
        <property type="term" value="F:ATP-dependent chromatin remodeler activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034728">
        <property type="term" value="P:nucleosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18659">
        <property type="entry name" value="CD2_tandem"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000130">
        <property type="entry name" value="Chromodomain-helicase-DNA-binding protein 2 isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10810:FF:000005">
        <property type="entry name" value="Photoperiod-independent early flowering 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1440">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056302">
        <property type="entry name" value="CHD1-2/Hrp3_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025260">
        <property type="entry name" value="CHD1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023779">
        <property type="entry name" value="Chromodomain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45623:SF14">
        <property type="entry name" value="CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45623">
        <property type="entry name" value="CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13907">
        <property type="entry name" value="CHD1-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23588">
        <property type="entry name" value="HTH_CHD1_Hrp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01176">
        <property type="entry name" value="DUF4208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00598">
        <property type="entry name" value="CHROMO_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="11" id="KW-0804">Transcription</keyword>
    <keyword evidence="9" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Chromo" evidence="14">
        <location>
            <begin position="296"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="Chromo" evidence="14">
        <location>
            <begin position="399"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="15">
        <location>
            <begin position="499"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="16">
        <location>
            <begin position="799"/>
            <end position="962"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1022"/>
            <end position="1092"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1292"/>
            <end position="1378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1470"/>
            <end position="1496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="50"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="63"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="112"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="140"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="200"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="232"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="1022"/>
            <end position="1035"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="1070"/>
            <end position="1079"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="1317"/>
            <end position="1345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0015312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="19">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1662" mass="187963" checksum="7289AB73038079B5" modified="2023-09-13" version="1">MAEIKPSQDSSAYEDDRASSLAPRKRHPSRSPSDLDDEPSKTPSKVNNHSISDGSSFDSSSGNDDDDDDDEPGYQPKKSNSKRQDESPYDSFEEVNGSDSSQKRANRAPRTSRAEFKNVDAELYDLRRSGRSRRPPKIIDDDDEDEDDEEESNFENDDDDDDDDASNSGSDEGSEDSGSDYGYGSKQRSRKQKQSPRSSTRKDSRSNDRNQRTTSRDTPSSESDSDGDWKGSSKKSSSKRRKRGTNVNKDTESGVRYSSRGGQVNYNEDENDWGISSEDDKLPVYTKPAAPEEEGDVIESVHDFRRCRNTDEDDSDEPDDPHHNMEFMIKWKNHSHMHNTWEQYQDLRQYKGFKKVDSYIQRFVYPEIALKSDPNTMREEIEQSDVNREMLRDELKDYTLVERIIASRTAKTGETEYFCKWNRLPYSAATWEPEDQISENHQAEIDAFLDRESSQKVPYKTTIYPKGQRPQFKRMATQPEFLVGGQLRDYQLTGLNWMSRLWSRNENGILADEMGLGKTVQSISIISFLFHQHNLYGPYLVVVPLSTIGAWQREFERWAPDMNMIVYIGDAASRQTIRDYEFYQKGSTNKIRFNVLLTTFELVRMDRAELDRIKWTYLAIDEAHRLKNKQSQLHETLKDFHTANRLLITGTPLQNSVKELIALCNFLMPDKFVDDDVEIDMADAEQEAKIRDLHESLKPYMLRRLKKDVEKSLPKKTERILRVELSQLQTHYYKNILTKNFAVLNKGMSGHGQLSLLNVAMELKKASNHPYLFPNAEVVSDRREDQLKGIIMSSGKMVLLDKLLTRLKKDGHRVLIFSQMVRMLDIMTDYMALRGFAFQRLDGSVGSEARKRSIEHFNAPNSIDFVFLLSTRAGGLGINLETADTVIIFDSDWNPQNDLQAMARAHRIGQKNVVNVYRFVSKDTIEEDIIERAKRKMVLEYCIIKQMDTSGLEILQQKKAAETSTGFTKDELSAILKFGAQSMFQQTEGATNKKLDELDLDEILARAEDHDTTDAVNMAGEREQFEAEERAKLEEQLYTPRNRGRVSYAEGRNNSPSPESEGRRRKRKASGSASSAAAGPKKKRGAGLDPSELNTKDLRALARGMLKFGIVTDRYKDVVAEAELEDKEEDVIKMEAEELIHACEDALGVPHDSIDNQDDDEDLPYAKKNAKAVLITHKEVDKMNAGQMILRLKDLRAMNRRLDGTDLTKFRMNVPLKPVMNWSCPWGQKEDAMLVVGIYRHGFGAWDKIQEDPSLGFAKKFFLSTQDAKDLKKIPKALHLVRRGEYLLKTLRESERDKKTRQSAASPSGARREPGKSSRSSGSNNNANTSSSKDQSKSSSSSSKTRPSKPRSTRSSRNGAGSGSEGEESAGGQNDESSKELLRAVGRDLRTIKESDKKPVEPQVIAECLARIGREIESLVENASSSRSRSERDRDRLSKQLWTYAGKAFPTGAIHYAQLRKGYLDIKNAEEKTSGSSRHRQQSEDGRRPAHRRSIGNGKVRMVAIIDLGQEETAVLVLYGHQTHDGDPKIEHTPVREGAIPRKTIALDTEITAPVPRETEAALRDTAIDQMTMRMRAMPMAVAITMTDQGTVASGIGHMTEVIATKTRETVVEIGLEEAETGIVIGAEIDRATVATVGTMTADDTGRVGQQVVEGDENRLME</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWJ8</accession>
    <name>A0A9P6MWJ8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">endo-polygalacturonase</fullName>
            <ecNumber evidence="2">3.2.1.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BGZ80_009239</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>(1,4-alpha-D-galacturonosyl)n+m + H2O = (1,4-alpha-D-galacturonosyl)n + (1,4-alpha-D-galacturonosyl)m.</text>
            <dbReference type="EC" id="3.2.1.15"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the glycosyl hydrolase 28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.15" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010000535">
        <property type="protein sequence ID" value="KAG0016414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWJ8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004650">
        <property type="term" value="F:polygalacturonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045490">
        <property type="term" value="P:pectin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000743">
        <property type="entry name" value="Glyco_hydro_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050434">
        <property type="entry name" value="Glycosyl_hydrlase_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31884">
        <property type="entry name" value="POLYGALACTURONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31884:SF1">
        <property type="entry name" value="POLYGALACTURONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00295">
        <property type="entry name" value="Glyco_hydro_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00502">
        <property type="entry name" value="POLYGALACTURONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7 11" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040280278" description="endo-polygalacturonase" evidence="12">
        <location>
            <begin position="18"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0016414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="386" mass="39788" checksum="B1E1C92A081088DD" modified="2023-09-13" version="1">MKIFAIITALAATAVVASPIEKRSSCTATSYKQIAGTKSCSSVVIQGPFTVPANEVIDLTGLQTGTTVKITGTITFAKGNLDMSNNLITFGGTNIKIDGTSGLLNGSGPQYWDGKGSNGGVNKPKFVRLQKLSGSITGLTILGSPIQTFAISGCQGLTLKNITIDNRGTNYALGHNTDGFDVASSTGLTIVGAKVYNNDDCLAVNSGSNIVFTNNYCSGGHGISIGSIKAGAIVDGVSITGNTVVNSANAVRIKAYADAKGGKVNNVTYSDITMSGITDYGIIIQQDYTNSGATGKPGGDAPITNVNLYNVHGSMAKGGESVYILCANCSKFNFQKIAITGGSASKCTYVSGSCVRRFITTPVQNEFILTLILLLYSGISPKPSGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWU4</accession>
    <name>A0A9P6MWU4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NodB homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_009575</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000587">
        <property type="protein sequence ID" value="KAG0015867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWU4"/>
    <dbReference type="OrthoDB" id="504708at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10919">
        <property type="entry name" value="CE4_CDA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052740">
        <property type="entry name" value="CE4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45985">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45985:SF3">
        <property type="entry name" value="CHITIN DEACETYLASE-LIKE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040293587" description="NodB homology domain-containing protein" evidence="1">
        <location>
            <begin position="29"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="domain" description="NodB homology" evidence="2">
        <location>
            <begin position="58"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0015867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="474" mass="51016" checksum="E80D5023E83FFF22" modified="2023-09-13" version="1">MRSSGFSLTAAAASALLCLGLASTTAEAATCDPAACVHPACVCPSLTPPKNMDPKTVPQFFTLTFDDAIQAQTVPVAESLMKSHTNPNGCPIKATWFAQTIYSDYSLIQQWYANGNEVADHTMNHIGTPPAEEIIGNLKAINAFSGIPFAKMNGFRAPFFNYSEVTFEILGQEKFLYDSSTGATPSNAYWPYTLDYGLANDCWTGICNKDIKIPGLWEVPMHAIMDSDLLDATAHSMDVQLEISSSIVADVLRKNFDRHYTGNRAPFGIFLHPVHVGNATQLYNDLFSYARSFPDVWFVTNQQLLEWMKNPVPASQMADQPYMKCTLPAVGKEICNGLDDTNSGTVDKGVLETCNFVAGPWSTCYGCPKASPTVEDPVPERVVPAGPTGARTPVPSTCAMEWWDPITAQCLCSTSNCTFTDTALTTSNTTNSSISGPSNGNTIHSSASNNKISKAAWTGFGLIAAVAAGLAQML</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MX31</accession>
    <name>A0A9P6MX31_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">MIT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_009297</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000542">
        <property type="protein sequence ID" value="KAG0016329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MX31"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.80">
        <property type="entry name" value="Phosphotransferase system, lactose/cellobiose-type IIA subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007330">
        <property type="entry name" value="MIT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036181">
        <property type="entry name" value="MIT_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37327">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37327:SF1">
        <property type="entry name" value="MICROTUBULE INTERACTING AND TRANSPORT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04212">
        <property type="entry name" value="MIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116846">
        <property type="entry name" value="MIT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MIT" evidence="2">
        <location>
            <begin position="48"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="588"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="118"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="140"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="175"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="346"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="377"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="390"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="407"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="436"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="461"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="488"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="521"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="540"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="588"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="608"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="641"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="656"/>
            <end position="672"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0016329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="999" mass="106601" checksum="20E680B111A4A829" modified="2023-09-13" version="1">MAHAGKRSESISSGSDYKNLHHSNGSTGLMPPDQNRPRSSSSSKALLTMALLEAQSAVQLDNDNDISGALDAYQRAVNLLSKVMETSNSADEQERLRTIHDSYLFRIRLLSTPPTPTTPTNDSMTQSPTSPLPQSPISALPQSPISALPQSPPPQQPLPPLPRQPNPARTTGTVSSTLASITPASSSSNISSQQNGDDPSSSSSDGTQISGSVVQSTVSPARRIRKHVPVPIQPPPASGSIIQPPTEPRTPRQRSDSTSTAEHGSSYGHVRHHTRSHTGGSTRITGDLIHAAEQLQIQAQHRVPGVPKVRSRDHLGVPIHSAPTAPLPPTPALGQPPSSPPPVPMPSGYGSASSTPTHSNPSTPNMATASTFSSLPSSPPPRAPLPPASINLTSPPASPANNSRRISPLVPSSSSSSSQQQGSQKSFQSPPDSSPEEEKSNESAHSKFYDEDLVSDEWLPNLTSTGFSASETLEYSSEDPYPRERVTSKGSFTGSQLETRPKAAKRASAEHEGQSTVETPQQKQQQQQQQQQQQPAALQHQRSFSQSSNVSAHLSISSQTRSPLAAPMYSFQQGASSISSLHALDGSSHKRISDSSRSLKESSPLARSSGSPAATTNGAGAASSPGQSTSRPSLLHHQHSSSKLSATLSNSSSASPTLDKTWSPSASNSHANGPSGGMTLYDVITDDPFGNMTFPFPPPFVEQPPTDPYLRCFWLMRKLEQTMTTGGFLTKRMYVPRTIWYQSLVRLPAADSKMSACQTLNNLFSKLAKQSQSGHLNILVEGGPEVDVERMTILKELEALETAANQVQSKLSKKLSFIPRPGKNGLNLTIATNQSYTEDMQGPTTGGTASIYGAASIYGDSYSWSTGEEPPLPGNLGHEKSVKKGGVSVGGSGPDAGVGGLKSQWKSFSKSVQKSIGNDKVDDTSMYTEAVIRLFQSSYILESMLRHYAPSPYQLNIQISNRLRRLCDVLSQVICAFVVRDLGELMGKYVKRVGAWVAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXE2</accession>
    <name>A0A9P6MXE2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RGS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_008425</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000456">
        <property type="protein sequence ID" value="KAG0017301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXE2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07440">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.167.10">
        <property type="entry name" value="Regulator of G-protein Signalling 4, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016137">
        <property type="entry name" value="RGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036305">
        <property type="entry name" value="RGS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044926">
        <property type="entry name" value="RGS_subdomain_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10845:SF192">
        <property type="entry name" value="DOUBLE HIT, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10845">
        <property type="entry name" value="REGULATOR OF G PROTEIN SIGNALING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00615">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48097">
        <property type="entry name" value="Regulator of G-protein signaling, RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50132">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="18"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="RGS" evidence="3">
        <location>
            <begin position="366"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="280"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="521"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="646"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="286"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="318"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="521"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="545"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="659"/>
            <end position="677"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0017301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="677" mass="75054" checksum="8D8EC6B9ADCF9BC8" modified="2023-09-13" version="1">MIFQLRDLNDGFGIRNELVITSIVSVPSTILYFIVPGIAPRFSLYFDKSTFMVIIFAVSHIISTVIPLFKHYKANSHSCSYTSRFLQRRGQRNENTAPSVIGSRDISKNVGGVGYQGWSGPEDIPLDEQRNRATLQEDRFVGDQVLPITTPIPPQPVRQNNSTQGRHPSRQGSAVDQLTDPVRKNSFGNLNMSMKNLVRNQQREGVFSFGRNNTLGDEISSKKTDWDEFLRVLEDRTFFKKISAFTVREFCAENTRFLYEVSRLEKRAIQYEHLRSLAMNTDEASQQQQQQQQQQQRGDSGADSTAQRTEIISHTDNTDTAQQGSNSSDNPPPRIKKIISASSMSSTVPMLQRPMTSHDYDDSEPSSPLGSFSFSVFKRNGSSNQTLPNLEEDAVFESKPAVSFGAMPSLDVITTPTAASVSFDPLPMPPTLLIQFEYIYKTFIVTGARLELNLSHDTLQDIHRKARRGEWRSGMFDAAIFEIQELLFRDVWPKFVTSSQGLNYNGLPESDLQSTQARLKEVDLTSDRSSARVGGSGRTSAYFPEQQSAGPSNSGSPIPMTSSLSRATSSKATVVSVGDTGMEGINGVVGRSGSGTSARSQGHDTFNEEPNQTGFKTWLKNTSRRGISAVKMNSDDVEEESVGIVEQSRKSMGNRRSDNSGLYSTSIQSSLAPVNRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MY01</accession>
    <name>A0A9P6MY01_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CRIB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_008619</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000472">
        <property type="protein sequence ID" value="KAG0017106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MY01"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.810.10">
        <property type="entry name" value="CRIB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000095">
        <property type="entry name" value="CRIB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036936">
        <property type="entry name" value="CRIB_dom_sf"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50108">
        <property type="entry name" value="CRIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRIB" evidence="2">
        <location>
            <begin position="98"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="52"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0017106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="165" mass="17812" checksum="FFD3CB4DC3E4DD1C" modified="2023-09-13" version="1">MGGFISKSKTPKSKDPRWQGIGPNTPLPGSPNPNSNSYGGGQRSHTLASLDNQTNNANNNRNTKTPAAKGNKSSKIMLLLKLDPKGGGQRKIITKNLISLPSDFRHTGHIGAGEVRSGQVDTEKIKNQMMEVAACLKLDLNAPMPVLKTMPVQPEDRENVYNGIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MY98</accession>
    <name>A0A9P6MY98_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">60S ribosomal export protein NMD3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BGZ80_008923</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the NMD3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000500">
        <property type="protein sequence ID" value="KAG0016809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MY98"/>
    <dbReference type="OrthoDB" id="203821at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000055">
        <property type="term" value="P:ribosomal large subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039768">
        <property type="entry name" value="Nmd3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007064">
        <property type="entry name" value="Nmd3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048899">
        <property type="entry name" value="NMD_SH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048898">
        <property type="entry name" value="OB_NMD3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12746:SF2">
        <property type="entry name" value="60S RIBOSOMAL EXPORT PROTEIN NMD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12746">
        <property type="entry name" value="NONSENSE-MEDIATED MRNA DECAY PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04981">
        <property type="entry name" value="NMD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21193">
        <property type="entry name" value="NMD_SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21192">
        <property type="entry name" value="OB_NMD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Nmd3 N-terminal" evidence="9">
        <location>
            <begin position="14"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="60S ribosomal export protein NMD3 SH3" evidence="11">
        <location>
            <begin position="245"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="60S ribosomal export protein NMD3 OB-fold" evidence="10">
        <location>
            <begin position="309"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="458"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="458"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="469"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="496"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF21192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF21193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0016809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="511" mass="58617" checksum="41129A942EC9F0C8" modified="2023-09-13" version="1">MEYRPELTQQQILCCSCGTTIPPNPTNMCINCIRNQVDITEGIPKHATICFCRNCERYLQPPMLWVACQLESRELLALCLKKLKGLNKVRLVDAGFIWTEPHSKRIKLKLTIQKEVFTSTILQQIFEVEFVVSHQQCDDCAKVMAQNTWKAMVQVRQKVDHKRTFLYLEQLIIKHSAHKDTINIKECKDGIDFYYGSRSHALKMVEFLTAITPLKSKASEQLISTDIHSGTSNYKFSYSVELVPICKDDLICLPPKVAKAMGNISPLVICYRIGNSIHVMDVNTLAVAEISTQTYWRTPFQALASVKQLQEYYVLDVEPCGPVRGKYVLADIQVARSGDFGRNDTTFFARSHLGGILNPGDSVMGYDIASSNFNNDAFDGLHRGSLPDVILIKKAYPAHRKRNKGRNWELRQLQKEEEEMAPRKQDQERIEQDYEMFLRDLEEDPELRATINLYKSDKAKKEADHAMTEDESDYEEEDFPEVQLDELLDNLKLDDGPDGEFEDDDEDMMMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYH3</accession>
    <name>A0A9P6MYH3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Duf833 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000447">
        <property type="protein sequence ID" value="KAG0017396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYH3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008551">
        <property type="entry name" value="TANGO2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17985">
        <property type="entry name" value="SER/THR-RICH PROTEIN T10 IN DGCR REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17985:SF8">
        <property type="entry name" value="TRANSPORT AND GOLGI ORGANIZATION PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05742">
        <property type="entry name" value="TANGO2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0017396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="438" mass="48381" checksum="417A57FB71FB1461" modified="2023-09-13" version="1">MCILLWTLPTSNHPRFKFAFASNRDESITRETSRADFWDVESILNRATNPTKVSTNTAQAEPGSLPGNGNVDGSNGDKIGILSGQDKQPAQTENYVFKETETTATGEEKVTLMLSTEDVPGTWLGITTHGDLVGLTNYRETAEYLAQKRPPKLSRGKVCGEFLVTMAAARDGGAVANDRAEQWIKRRAIGWDTEFEGLNLLVVQNAGEQQCVGGNREGSELTVYNTPENAVISDHPRQSIEPGSVVGVSNSVFKRPWSKVHIGTQALEKTLNESISLFGAGPRASLQAQHRSNTHPHLASDDDTVELAWLVIEMLTLLRVNTKPFPKDISESASLVLGLRERVFIPLVHEYGTRSSTVVLFGRNNRLAVFVEKVWHGPPDETTGDRIEFAPDSTDGLLWLQGLVGQPRKEWKRIEGQELEDLVRSAKEAHKFNVDTQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYN1</accession>
    <name>A0A9P6MYN1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Gamma-soluble NSF attachment protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">N-ethylmaleimide-sensitive factor attachment protein gamma</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_008057</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNAP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000426">
        <property type="protein sequence ID" value="KAG0017664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYN1"/>
    <dbReference type="OrthoDB" id="9984275at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005483">
        <property type="term" value="F:soluble NSF attachment protein activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019905">
        <property type="term" value="F:syntaxin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000744">
        <property type="entry name" value="NSF_attach"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13768:SF2">
        <property type="entry name" value="GAMMA-SOLUBLE NSF ATTACHMENT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13768">
        <property type="entry name" value="SOLUBLE NSF ATTACHMENT PROTEIN SNAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14938">
        <property type="entry name" value="SNAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040483612" description="Gamma-soluble NSF attachment protein" evidence="10">
        <location>
            <begin position="16"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="30"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="112"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="37"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00040047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00042485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0017664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="383" mass="42587" checksum="14C4EDDAD9DCB3D9" modified="2023-09-13" version="1">MLGLVLLILSAVVAAQTKPKQETFVPYMTTQRKEQLSSTPSSSSSPSSGSGRGVAGWFTRNIIEPLAGPRVPEHTITDYYFFLIAKLNNGTGLYLGMFQQWWVISELQEVPDTTSSESRGNRGGNPFEAQAEAQKQEAVQAKIKKDYHGAARAYVEAAKLYEKSGSQFNIMEAASAYEDAFKAYNMAKQTENAARLFRLNERGGSRAAKVYNQLGDLLKSQDAAKAATMYSEAAELFRSDGDGRALHAIIRQAEQLCILHQYAQAFTLYNDTIIPETMSQDILQYTTRDHVLNAIIAHLGATQGDWIVLEKDLEHFEDICPDFRTSKGLSVLKSLARAEREHDAVAFRDACQEFDRLHSSGMADWQVGLLLQEKLKLEDGDLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZW2</accession>
    <name>A0A9P6MZW2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004876</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000244">
        <property type="protein sequence ID" value="KAG0020044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZW2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032991">
        <property type="term" value="C:protein-containing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF161">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0020044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="390" mass="42512" checksum="9856358CD344A22F" modified="2023-09-13" version="1" fragment="single">MSRRELDSLFLPYSITPPSPSPSPSPPLFGDDYDKCSSISPLSTPPSSPSMDCRPQTLFRLLPTCSMPCGIKFGTWVSITLELLSEFGGFQYEASPNQNFKLKDGQSLLPLDCCLLYEWEGQISSQSPPNCSLVLEKRALQSTNWLGLENLSGPGIGSSGRGGLELRVLPTQEQAPVTFWISISSERDQGIVPLVLGPLTISSDIRRVDDTRQVLRPISVPQRNDLSPRMMLLKETWNNVPQGRIWDSAFTLIDIFSKKTTHNLYQPAPPVFAGKRILDLSAGTGLLGIFLAGLAQLELESFRANSILSSQTCPTTPLSCHSPTPPCTTVMLTDLADALGLINFNVSSNQDRIAPNINIVAKELKWGVAHLAQLGAGELDIVIASDVVYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N006</accession>
    <name>A0A9P6N006_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glutathione s-transferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_006238</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000307">
        <property type="protein sequence ID" value="KAG0019158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N006"/>
    <dbReference type="OrthoDB" id="414243at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050213">
        <property type="entry name" value="GST_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571:SF150">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14497">
        <property type="entry name" value="GST_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="18"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="2">
        <location>
            <begin position="87"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0019158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="253" mass="27860" checksum="F7E84F2F0F4F0133" modified="2023-09-13" version="1">MILPSLSSDILSNDKKDSKFSVLYFSFHGLGACPRALLSIGGAQWDNKIQSKEDWPQIKGTTPLGTLPILLETSLSTGETIEIPESGAIERYLARKFGLLGDTVREQTLNDVFYAQAVMLNTKFAEKVVAFEEIRKKALDQFLETTLPDWIKLCEKHLAGNGNTGHFVDNKASLTLADIKTAVILDTFLGLESEKVLNPTASPGLWKLKETVDTHPGYATWRKSEGFKNIDKDTQATAGAIVPFDVSKAHIFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0C7</accession>
    <name>A0A9P6N0C7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">EnoyL-CoA hydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ECHA7</name>
        <name evidence="2" type="ORF">BGZ80_004422</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000226">
        <property type="protein sequence ID" value="KAG0020297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0C7"/>
    <dbReference type="OrthoDB" id="448450at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="entry name" value="Lyase 2-enoyl-coa Hydratase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051683">
        <property type="entry name" value="Enoyl-CoA_Hydratase/Isomerase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42964">
        <property type="entry name" value="ENOYL-COA HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42964:SF1">
        <property type="entry name" value="POLYKETIDE BIOSYNTHESIS ENOYL-COA HYDRATASE PKSH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0020297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="270" mass="29168" checksum="56BE4C8D828276DA" modified="2023-09-13" version="1">MSEKEILYSKQGAVGTITLNRPKRGNALTAPLVNLFVDFLNTAIDDPTVRVIVITGNGKYFCTGMDLTPQDDTPSASDPVAATQSMFSTLAKSPKPTIARMNGPALGGGVGIVFACNFRFVHSSAYFSMPEVHRGLIPALISEVIVPQLGPFRSKQYMLSGERVSAQEAYRVGFVTSVAEDEESLDKKVKEYVDLLLQSGPGAMRDVKLLVDSVDQRGGDHQAVASYVREAFGKMISSDEASHGIGAFASREKPNWDEFGLGSEKLKSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0L4</accession>
    <name>A0A9P6N0L4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004607</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000233">
        <property type="protein sequence ID" value="KAG0020207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0L4"/>
    <dbReference type="OrthoDB" id="2348416at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0020207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="605" mass="69774" checksum="56CA68CEF57E870A" modified="2023-09-13" version="1">MTLSKDLPNELFLQIGLYLNRYQLVNCALVCKSWSISFIPQIWSNLEIGSDKPISALTEEDISCKASWIRTLAIYDCESTIRYSNVGKRCTQLQSLAITTTYSKDEPEMNYWRACRDLVKQNRRTLVSLMLKDMPLPASKPKYGGSNWSPLLSISQCPHSRLRRLRLESCELPYRHLKAFWDICEKLEVLELNNVPFELPRLRATTRKTSGPGDHPQKQNLGSIHQQRVVRFSNLLELTLDRSGPRSALKQLERIIRQAPKLKKLDWHIRNAQFPVTRFIYLLSGQSKYYRTPTPEDADPRGPLELCTAPSWPNLDSLRVRSWRYLELDPEDYLTIVKMIKRLQFLELPVDVMTPAIVDSLLQFHSDTLTVLDWRTVYFGQYSERENAASIQQVLSSCPNLTKVLFRFIHAQYLIEGGDSWVCCDRLEEIRFRLDMTLIDWNPPRLGATDQEKQDVSWAVFQQLGRLRKLRILDVNSSLQYTISMGLSLLSNLKELETIKFYGSQHMTPQDVDWIVQNLISLNTIEGTDRLVANHSRFASRMNPQDCALAAMFNRRGIKTPGSVYPEGYLDGLEVTWDNPQTESVSSDDIQTEINPLENLGDVFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0R6</accession>
    <name>A0A9P6N0R6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_003814</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000203">
        <property type="protein sequence ID" value="KAG0020662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0R6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0020662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="350" mass="38835" checksum="7A2F55243C18DCB2" modified="2023-09-13" version="1" fragment="single">VLSMIGGTIGKKGESNKKAVIGIGLGRSGTNANSTSQRSSFNSYLAGKVCSFAYLVVGVNGFYTSNKCRRLAPDEIPPRITSITDSVDYFLAEIRNIVKTKQDIADLWSCQPQQIKILRLDLGQACVHGASTLLPGDNHCEAGGNDLMKKAGPTVYREIPTGATNSISNIENNLLPPRGKDTSFESYRSGLQRVEDELNAFYNGSILFKKHQWGASRVYKAEYAITTDCLLKLIGGSIGRQRDMNCEASLGQFVTKTRFSFLHGSFLSYFAPRTRSLDYIAIGANGYCTSKKPLICGKIDIHRLNCRHCTAYMHRDIMERHNIYNVVCGHLLRQQRPRYLQPRNESGGYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-10-08" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0V7</accession>
    <name>A0A9P6N0V7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Bromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_004808</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000241">
        <property type="protein sequence ID" value="KAG0020082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004402">
        <property type="term" value="F:histone acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017025">
        <property type="term" value="F:TBP-class protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051123">
        <property type="term" value="P:RNA polymerase II preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040240">
        <property type="entry name" value="TAF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022591">
        <property type="entry name" value="TAF1_HAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041670">
        <property type="entry name" value="Znf-CCHC_6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13900">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13900:SF0">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12157">
        <property type="entry name" value="DUF3591"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15288">
        <property type="entry name" value="zf-CCHC_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Bromo" evidence="9">
        <location>
            <begin position="1294"/>
            <end position="1365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="43"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="127"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="922"/>
            <end position="997"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1450"/>
            <end position="1496"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="1061"/>
            <end position="1089"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="65"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="127"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="148"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="930"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="940"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="965"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="985"/>
            <end position="997"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1452"/>
            <end position="1481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0020082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1496" mass="169072" checksum="2EDE46CFD0EA257A" modified="2023-09-13" version="1">MSFAGFFFGNVDKSGKVEDLPEEFREALESLENSEQLTHLFSAKTLGVEDNEVQTQGASGGAADGNEEDEEEDQDGEVNFATIKSSFEHDKDAVDYSEINDLAVDNTEQMFSSRYLQKGLSAVKATATTAMRSSSLAKGKSTSRLDSMDEDYDAEGTDEEETPKAGSRRQSPTLTPAEKASMSLLQQQQLYLMEEQQKQQQQQQPTTSISKQTTAPISLPALPGAVPAAAPTEPIDVHAIYPAFEENKILKFSELFNTKRPKRFPHSRAKPAEFPTSNKFSRLYDQKKLFEKPEDPSNNKKQFLDYDAIEVPVDKDWANSLQWKVPEDKDYYSLQLEPWEEKIIWDDAVVPSKTEMNGDNTSLVKSSNKPVTELFAIRNYDLENGEWEESIIWDENKPYKPFSHVSLNMNDANVLFDFTSMDSKAMGEGFRVKRGKKVVFPAYRVVTNTNDPSEAETHRKLQIDRFNLSNDRFYEAHKEGRFHRVRQTFGQLVVQHALPAVKLMKPWYKNKLTKSEQRSFHRPQLQVTPNVEITFSRVKGSKKKNKKRKELGEVMRSFKDLTLRDHTNFVLLEYSEEHPAIIQNVGMGSFLINYYRKESMEDTHVPQMEIGEPFVLDIADASPFLGFGNVEPGQTISALYNNMIRAPVFEQPARNTDFLVIRNTYKGETKYYIRHIPHLYVVGQTYPVQDVPGPHSRKITTMIKNRLQISAFRFIRKDPHNRLRFAKLVKAYPEYSEIQIRQRLKEFAEFQRKGNNTGFWKLKASTPLPSEEEIRKLVTPEMVCLYESMLVGQRYLQDAGYGRAADGEDDNEDNEANMDIEEQLAPWITTRNFINATQGKAMLKLWGAGDPTGRGEGFSFVRISMKDIFLRQGESLEERLAQIELLPKSTHRYNVAEQQQVYREEITRIWNTQREALSRIEEIDGKNDEIGGDDEDEEESYNRQRREMSTADRNRVSPSPSLFGRYRDSGDRDRDRDMDDDNVSVAGSISSRTSVGNLGSSRNKYLIIKRLVRQENGESVWKSETIRDPAVMNAYIRQRQLIEESSISTEALEPTNDEAKNQRMKKRIMEEIARLNRNQERRRARAAAKAGTSTLEIPPVNPATATLKKKVVRQCSNCGALGHMKTNKKCPKYVDPSGALPNLGVTGTAYVTSGGVGGSMMSPPQVAMRQTSIPPGTPAMVRSTTANNEFFRQGSPQSAAVATSNKISIPKAVIDRVADLEKEREREDKEALVVRLPSKMLQAAPKRKRSESISQQNDMEDFMDYYPPVKSYGRRKKPDVELANIIENVLATILSMQEATAFLSPVSSKIAPGYDIQIKHPRDLTGMRDANKNSYAYRTVDAFLTDMRIMVNNSWHYNGEHSLWTKAAMVLLQKAEEILKPQMETIQRLEQEILEADTKANIYGGLNTPGGITGTPPPLANIHPGGYGLYNSLTFPGIGKPFIGFTSPPARNHNNGNSNLNTAPASISTVQDGSAGPNSNVGAAEVQVKSETMEWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0X5</accession>
    <name>A0A9P6N0X5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Hsp70 family chaperone</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_005179</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000257">
        <property type="protein sequence ID" value="KAG0019854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0X5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187">
        <property type="entry name" value="ALPHA KINASE/ELONGATION FACTOR 2 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187:SF5">
        <property type="entry name" value="HEAT SHOCK 70 KDA PROTEIN 12A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0019854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="549" mass="61624" checksum="68DC7FE3DB9B4616" modified="2023-09-13" version="1">MALTDFDPEDYPIVVAIDFGTTFSQVNIIANPIQTPKQNVQYAKTPTLNLYKEVNGKYKMVEWGWKSKLQMETPAASKYIQLYQYKPHLDENLALVPWKNTVSVPTAISDYLEALHEYVAEKILQEFGRSYSRKSFRYCLTVPAMWSDKAKDVMRKAAVRAGLISGDDHPDRLTLVSEPEAAALYCEKACKQYNLSHGDRFMICDAGGGTVDLIVYEIAMTAQGRHLSEVTKGHGASCGSMFIDLNLGNLLIEKFKRQGAVFPKSVIQTLVETFAYQLKPQFDGEEDMYLALPRSDCFDDIRDPRSIGIDGGYMCLKASELKRVVFEPVVKQVLALIREQLRGAKRCSAIFMVGGFGSSNYLLDRVKQEFGGVVKTISSPHKPEMAVVCGAVYAGMNPKIVTARITRRCYGIRMSRAFEEGVDPIKFKVMRIDGARCEKRFSPIVRKGQKVEVDECVTNSYSFTNEKGMRFSMDIYAIDGNPPRYVTDAGVFELAKVSIPTPFKPWDPIGHKVEILVKMYFGLNEIKAEGLVQGKKYSTSIKFDSGDSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N107</accession>
    <name>A0A9P6N107_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">26S proteasome non-ATPase regulatory subunit 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">PSMD6</name>
        <name evidence="6" type="ORF">BGZ80_003863</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Component of the 19S cap proteasome complex which acts as a regulatory subunit of the 26S proteasome, involved in the ATP-dependent degradation of ubiquitinated proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">The 26S proteasome is composed of a core protease, known as the 20S proteasome, capped at one or both ends by the 19S regulatory complex (RC). The RC is composed of at least 18 different subunits in two subcomplexes, the base and the lid, which form the portions proximal and distal to the 20S proteolytic core, respectively. Component of the lid subcomplex of the 19S RC.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000205">
        <property type="protein sequence ID" value="KAG0020637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N107"/>
    <dbReference type="OrthoDB" id="1452at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005838">
        <property type="term" value="C:proteasome regulatory particle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.570:FF:000005">
        <property type="entry name" value="26S proteasome regulatory subunit N7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019585">
        <property type="entry name" value="Rpn7/CSN1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045135">
        <property type="entry name" value="Rpn7_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049549">
        <property type="entry name" value="RPN7_PSMD6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14145:SF1">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14145">
        <property type="entry name" value="26S PROTESOME SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10602">
        <property type="entry name" value="RPN7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21154">
        <property type="entry name" value="RPN7_PSMD6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 6" id="KW-0647">Proteasome</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="5">
        <location>
            <begin position="188"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="65"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00093435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00093502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0020637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="385" mass="44226" checksum="75130D8E51B8D76B" modified="2023-09-13" version="1">MSSEEVPKIPSIELSQNRFLLTSGPKETHAQAQEAIMNKIKEDNMAPFYELICEEQGWPVDTALLNQMKKENEEALKKLDDRLKDAEENLGETEISDTLLARAEHFAKIGDKEKSLTAYRVAFEKTVALGSRLDILFANIRTGFFYRDNDIVSRNIEKARTMIEEGGDWDRRNRLKVYEGAYLMTIRNFKGAADLFIATLSTFTSTELMEYKDFVTYAVLSSVLALKRVDIKNKVIDSPEVLEVLHEIPHLEDYLRSLYAGEYAKFFVSLAALETSCMKKSWVLFPHYRYYVREMRIRAYAQLLESYRSLTMQSMAHSFGVSEEFIDKDLSKFISAGRLNCVIDKVNGIVETNRPDAKNAQYQQAIKQGDILLNRVQKLSRVINV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N149</accession>
    <name>A0A9P6N149_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Threalose-6-phosphate phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">TPS2_2</name>
        <name evidence="3" type="ORF">BGZ80_004855</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the N-terminal section; belongs to the glycosyltransferase 20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000243">
        <property type="protein sequence ID" value="KAG0020054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N149"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005946">
        <property type="term" value="C:alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003825">
        <property type="term" value="F:alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004805">
        <property type="term" value="F:trehalose-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005992">
        <property type="term" value="P:trehalose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03788">
        <property type="entry name" value="GT20_TPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01627">
        <property type="entry name" value="HAD_TPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000036">
        <property type="entry name" value="Alpha,alpha-trehalose-phosphate synthase subunit Tps2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001830">
        <property type="entry name" value="Glyco_trans_20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003337">
        <property type="entry name" value="Trehalose_PPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00685">
        <property type="entry name" value="T6PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10788">
        <property type="entry name" value="TREHALOSE-6-PHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10788:SF123">
        <property type="entry name" value="TREHALOSE-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00982">
        <property type="entry name" value="Glyco_transf_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02358">
        <property type="entry name" value="Trehalose_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="62"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="839"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="88"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="850"/>
            <end position="867"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0020054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="911" mass="101118" checksum="CF3BD12EBF47EABD" modified="2023-09-13" version="1">MTTLHSTSSTTSLSVPRVVPLTELPETAQILLSENPRLINVTHQMPYSCTVIDRSYHSSSANGAPTLGGSTGLPNNRRASLAVPRHPAQPTSPTEAETPTSIMGTLSGANEITDPALLEDGDCILNLRRGHSALYSGVRTLVKEYETIQIGWVGEVADQDGYIVPCKNLTEKHKQNMKEKLWQREKVVPIFLDDDKAAGHYEGYCKSVLWPLFHYILWDEATDGRIEKKNWEDYVFVNQQFADAIAEQYRAGDIVWIHDYHLLLVPHLLRQKLPGAAIGVFIHTPFPSSEIFRCLPMRVEVLNGLLGANQIGFQTYSYARHFISCCTRVNGYESTPRGVDAKGSTVWVGTFPIGIDAARVEAQRKAPGVLPKIEALRKTYKGKRIIVGRDKLDQVKGVQQKLHAFEKFLNDYPEMQGEVVLIQVTSPPLVENLKLETKIAELVAHINGTYGSLNFTPIHHYHQHIDRDEYYALLTVADMGLITSVRDGMNTTSLEYIMCQSENQGPLILSEFTGTAGSLGGAFLVNPWDYQGVARVIYDALNISDEDKRVRHGQLLNHVLKYTAQSWAQNFITELLRNVSTWEQSTPTPYLDLNVIVNKYNSAQKRLLMFDYDGTLTPIRKTPGAAIPQEHMLKALTALSNDPKNIVWVISGRDQQALDEWLGDVENLGSFIEHKRSSLTWHYRMADPEFGAFQAKECQNHLENAVLSKLPVEILVGKKNLEVRPTTVNKGEIVKKLMLQHPDVEFVICAGDDKTDEDMFRALAGVNNGNGSRRSSLKNRISNGIIESYNNDLIAETAAKIAEAAFKHSREHGTHHRQDGAGPNVIVSAEIEAHLKVPASFSTSSPNGPTTPGSAASQTSSTSQGSTEYLVDEHFSITIGHALKKTLANWHVTSPEELIRVMGVLSGVVDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1A2</accession>
    <name>A0A9P6N1A2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_002282</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000156">
        <property type="protein sequence ID" value="KAG0021480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1A2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="57"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0021480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="76" mass="8054" checksum="4D24E38F086D9A33" modified="2023-09-13" version="1" fragment="single">RRYRKGDTDGKTDQVLVCESRLSPSYSNGNAEDNENTEGNENAEGNENNGGNGNTEGNGNTEGNENTEGNGDTEGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1Z0</accession>
    <name>A0A9P6N1Z0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_002146</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000152">
        <property type="protein sequence ID" value="KAG0021571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1Z0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0021571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="259" mass="28581" checksum="F43EA1EC570E7A52" modified="2023-09-13" version="1">MHTLLGAFYIVGPGAWIILHIGWILVVVLYSKALRMQNPVDEEMAVVRLHSQSTPNTRGSLLESPRKSNGVDLNDKSMQNIGIMSGSRLHQQQHLSHKPGDPGLKFSSSSHIAISRTPKSPKDIDQGQSKSNSLQYIDADDIQSDHQNDLSDNDGEAVESGLGPEQAQSIGALDETKSSTADIPLDGKGWWIRQIEGRRRGEICPCTLNWKGSNETESCWCGKERQVRYSQVHSARASTDWRPRAGKDRSTSKSPVRSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-10-08" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1Z2</accession>
    <name>A0A9P6N1Z2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Arm-like repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_003033</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000178">
        <property type="protein sequence ID" value="KAG0021100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990234">
        <property type="term" value="C:transferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.80">
        <property type="entry name" value="E3 ubiquitin-protein ligase SopA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056251">
        <property type="entry name" value="Arm_rpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847:SF637">
        <property type="entry name" value="WD REPEAT DOMAIN 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23948">
        <property type="entry name" value="ARM_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="16"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141571">
        <property type="entry name" value="Pentapeptide repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Arm-like repeat" evidence="5">
        <location>
            <begin position="262"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1263"/>
            <end position="1304"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1305"/>
            <end position="1346"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1354"/>
            <end position="1388"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1389"/>
            <end position="1430"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1437"/>
            <end position="1468"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1475"/>
            <end position="1509"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1509"/>
            <end position="1550"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1551"/>
            <end position="1592"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1593"/>
            <end position="1634"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1635"/>
            <end position="1682"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1683"/>
            <end position="1724"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1733"/>
            <end position="1764"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1765"/>
            <end position="1806"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="138"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="146"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="162"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF23948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0021100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1943" mass="214831" checksum="EEA745BAFB454EC8" modified="2023-09-13" version="1">MQLMFKFCNREKGSRESEAREEPSTYKNMGWNLFSSPTSKLPLGDILELANKYLELARKGHDPSKAVHLCRNAKSLLKDAETVFSKGPKDPILKDGIAKAYHEHGKLLDELGYHEKAQRSLTKAEAWGYIPVVSQHIDTPRPDHLSGSSGRSPNSSDAIPDTHQSMQESDISQPGRQSPGQDVTLTKVKDDIPESSENVVPVPKKIFDQNVIPPVARYTLPGVGERITSTPQLAYCLGLLQPSLVSKEGLSEIESDWSRVRTNDPDEQQRLQTMATDLIRAFVRDELKMPGVVAEVVSLAAVLDKDNFRKLLQIFVDGIDQSVLLNVHLLEGLAQLMRNAVEGYINADDLVKTLKRLNALLNSTDSQSSRHVFQLTLTISNVLDGMVDSQVEGIPREQLHEPLSKYLEELQESPDPYLVYQAAYASQAMMYISDDEPFLQTALRRTGKVVQGISGLVSAVKALDLVGFVEGLQSIQEGLAGVGKVVNNAYSNATTLAKSGQSLLQSLKEGSNFSGKRAWYPALRGLDRLIQEGRFAEFEKLIREAPCSRDPAFQWGVCQRLGEIAANNVWDVNTRQCAVDFLGEMYEDDATWGQQTSIKQWILQILNQLADPSMDALASQAQTLLQGLERGSSTEKSALFQVYKKSNSGPYPIVVTRPPQESRLLDGVQNKPDVETPLRQLKRERLRDRDRDVYISPRAKVSQKATDDFDLTSKVQEFLESDRKVLLLLGDSGSGKSTFNRALEISLWDKYTSIDRPIPLFIHLPSIDKPEHDMVAKQLRRFDFTESQIKELKSYRKFIVICDGYDESQQTRNLYVSNELNRPGQWQAQMVISCRTEYNGVDYKDCFQPTDRNNPGNTQLFEEAFITPFNNGQIQDYVERYVLLNKPPWESKDYEQAFQQVPDLRGLVTNPFLLRIALDVLPRLLGSSSELSKARITRVGLYDEFVAEWIERSKMRHGEIELNPRDKTALKAMSVSGFKKHGITYLKKLVTAVYDHQGSNPVINYSEYEDKKTWKGTFFNENDGVHLLREAVPLARNGGQYRFIHKSVLEYGLALTVFDPSEYSKNNEPTPATSDHEGTCSTPSLESAPITIDLSLLDSPLGKRSLLGEPSILLFLKERAQQEPIFKDQLRAIVLLSKTDESVCIAAANAITILVRAGVQFNRVDLRGIKIPGADLRFGVFDSALLEGADLRNVNLGNVWLRQASLNGAQMMGVQFGELPSLLEDSDIKRCVFSPDGKIYAVGTQSGKISLYDSSSWIKIRSLEGHKNGMMSLAFSATSDRIVTGGNEGAVRVWDVDSGECIHDLDAHINFVCVVAYSPRGGQIVSASYDKSLKFWSTDSGKCIHKIQDIKCGVDCAVYSPDGDQVATGNGDGTVQLWDPSSGDRFHILQGHTESVNCVVYSPKGNRIASAAKDRTVRIWDVVTGECLHTFQGHSDVVYSPKGNQIASGGGGKTVRLWDADSGDCVHVLKCPEPVSSIVYSPKGDQVASWSYDSPVRLWDVVTGACANTIRHDGLVYGISYSLNGNQIASWSLGKTVRLWDVNVDDVAHPIQRHEVAVTSVACSPKGGHIASGSKDGNVRLWEADTGNCVHTLQCHSGLSASIVYSPNGHQIASGGYDKAVRLWDADTGDCVHTLLGHESEISALAYSPDGNQIISGNSGCWGSTECAVRLWDVGTGKCIHVLLGHKYGIHTVVYSTKGNRIASGDYNSTMRLWDANTGDCIHIIQEYGRYDIVFSPKGVQVASGTMDNALRLWDVDTGDCIHILHGHTHYVRNVAYSPKGDQIASGSIDGTARLWDVVTGDCIHILQDHCYFLAFSPSGDQILSGCSNFSYSSKLWDVASGRCLLSISDFDGRVGCAAWENTTDGQYIVTGCHDKSVRRWQITKAGGKHQAVLCWTSSNEVLTVSNATFENVQGLDGPNRELLRQRGALIKNLSTLGKQLLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N206</accession>
    <name>A0A9P6N206_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">Protein phosphatase methylesterase 1</fullName>
            <shortName evidence="6">PME-1</shortName>
            <ecNumber evidence="6">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_003762</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Demethylates proteins that have been reversibly carboxymethylated.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>[phosphatase 2A protein]-C-terminal L-leucine methyl ester + H2O = [phosphatase 2A protein]-C-terminal L-leucine + methanol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:48548"/>
            <dbReference type="Rhea" id="RHEA-COMP:12134"/>
            <dbReference type="Rhea" id="RHEA-COMP:12135"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17790"/>
            <dbReference type="ChEBI" id="CHEBI:90516"/>
            <dbReference type="ChEBI" id="CHEBI:90517"/>
            <dbReference type="EC" id="3.1.1.89"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the AB hydrolase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="6"/>
    <dbReference type="EMBL" id="JAAAID010000201">
        <property type="protein sequence ID" value="KAG0020702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N206"/>
    <dbReference type="OrthoDB" id="194865at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051723">
        <property type="term" value="F:protein methylesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016812">
        <property type="entry name" value="PPase_methylesterase_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14189:SF0">
        <property type="entry name" value="PROTEIN PHOSPHATASE METHYLESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14189">
        <property type="entry name" value="PROTEIN PHOSPHATASE METHYLESTERASE-1 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF022950">
        <property type="entry name" value="PPase_methylesterase_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0719">Serine esterase</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="9">
        <location>
            <begin position="72"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="9"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="156"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="181"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR022950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR022950-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0020702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="329" mass="36345" checksum="AF9B02F252530815" modified="2023-09-13" version="1">MTAENSIHTTTATANASSEAPTSSDKDRFSPLDWSAFFETKRQVSIPIELDPSNITFSVYEINREKTDLPVIVLHHGAGHCALSFAATARELRTLVGDRARILSYDVRGHGETTSADQLNLDIDRLAKDLQNVLLTLYTPASSVTAMPELFLVGHSMGGATVTEVATRELVPNISGIAVLDVVQAYKDFAISNVRHWCETRPATCETVEQAIQWGVDSGTVRNIQSARVSFPGMVKRSSTESTYTWYTGLLATESHWSSWFDGLNQKFLTIKPKKLLILGGHGFLDDEMKAAHEQGKFQLSIFADAGHAVEEDDPIRTAKELVEFWKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2E8</accession>
    <name>A0A9P6N2E8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_001073</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000124">
        <property type="protein sequence ID" value="KAG0022095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N2E8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="49"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0022095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="78" mass="8754" checksum="39B26BAD8923E5FA" modified="2023-09-13" version="1" fragment="single">MYAGIGAGVAVLVLGVALFFYFRNRNSKSHNNPTKTTKEDIPGPLPPMQLVQQTQYLPPQPQQQPQQQPQQHLFAQQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2P5</accession>
    <name>A0A9P6N2P5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_000305</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the WD repeat MORG1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000106">
        <property type="protein sequence ID" value="KAG0022411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N2P5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051980">
        <property type="entry name" value="WD_repeat_MORG1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22842:SF3">
        <property type="entry name" value="WD REPEAT DOMAIN-CONTAINING PROTEIN 83"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22842">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="111"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="153"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="42"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="67"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0022411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="215" mass="23056" checksum="B072E7EE104A1FD8" modified="2023-09-13" version="1">MPKGASRMPAPPTMSIAATLAAHRNKTDKPRKSQSAARQETSTSTGISSNSSQSAIIAQQSHSATSNHTPTSLQATSRPKAQIPLEHTAPSAAPSSSSSISLPIYEDNVISDATGSQINACQYNSTGEYILTGGVDRVIRLWNPTTRFCIKTYEAHGWEVLDLAVSPENGKFASCGGDKSVFLWDVLSGMTIRRFPGHTQARTMRQYDYGTAGHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3R0</accession>
    <name>A0A9P6N3R0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008588</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000047">
        <property type="protein sequence ID" value="KAG0023674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3R0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005689">
        <property type="term" value="C:U12-type spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052831">
        <property type="entry name" value="Apoptosis_promoter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48190">
        <property type="entry name" value="PROGRAMMED CELL DEATH PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48190:SF2">
        <property type="entry name" value="PROGRAMMED CELL DEATH PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="213"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="429"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="604"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="25"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="437"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="607"/>
            <end position="627"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0023674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="724" mass="79756" checksum="424DEB1BA8999FEB" modified="2023-09-13" version="1">MGLALVHPASTPKLSREVQKYDSKALASTTANAPAATSNTSNVDSGAEATTTCGINSNSEPTTAHNSNTNIDTKAAPTHNSSTNGGTEATSRNGSTNSNAGITTASNASNADSGSEPTTTCNSGTSSGAEVTTASDTSYADRGAKTNRSTRGGAETATTSDTSHVNSGTETTRRPIRPPNIADSLTTAQPKIKSPLAPSLPQLSLTSPLHAPQMPALVPMSRPPNSENTTATAQPKTRYLPPTSSLSHPPPLHPPPLHPPPASISLTPSRLYEIKTRIKVVHAEMQQELDKARRIVTEHERLQEGWDEGGTDMETETASIMQRTKETKTPKTANCEPSVEDDPAYISAIYNAKRLKEELENLNANLTPERLAVVAKKITKALKRKEWKKRRITKMQEYRDTTEERRRKLNAEIDRKCEKILARDKKKEKRKLAKQVAKQERRQERRQEARKIAQGKQTVALVQKLQRLKTLRRERMKRAGHFFPEEDNEFFERIHKAEEALKQPIEKSANWDTNSSKKQMEKEKKFEVGLEKQEIVNTNCSSAKVGMSPLQDNESNAAENAPVLDEITVGTDTGTSKRKPCQVDVFEDSLQTDVPIDQTILPPTKMQKLGQGSSQQQQLLQAQQESQLLSEKDQEQGCIVSLELPTHFTPEQPNVEGSTSTALILGRVRRKKLGKPINYRDVWSSYQISQKDGLRKERIATPIPDGLGAPPDKPSSLEWAKYLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3V4</accession>
    <name>A0A9P6N3V4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_005011</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000025">
        <property type="protein sequence ID" value="KAG0024229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3V4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047146">
        <property type="entry name" value="Cyt_P450_E_CYP52_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24287">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24287:SF1">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="454"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0024229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="511" mass="58453" checksum="4CD1755B849F18F2" modified="2023-09-13" version="1">MHKNLILGTTIAGAIIAYALKPKKPKTELEAKGVPIPTTPTYLPLQIDGVLHYILSVLAGRDELEFLRAISTEMGNTINLRGFNQDFIIVLDPSSIQHILAKNQPNYEKGPEFQAIFHEFLGSGIFNADGEAWKTQRQLARPHFQTSEFRDAALINRHVDQLIKVIDNHISKSPDAPLDVQELFCRFTLDEASEFLFGETVNALELGNTEFSTAFNYAQSITAWRFRVPLWRYVVPTKQFLREIKKLDTFVYKIIDNAIARQEKRVMEQEQQPGDGKHEMKEGYDTLLDHFLSQRSEHGFDREYLRHMLLNFLLAGRDTTASLLSWTTWKLTQYPDVLAKLKQEIAEVIGPDTVPGYDDIKKLKYQKQVINEVLRLCPPVPFNMRQSVEEDLLPNGYYIPPGTPVSYSAYTTHRLPELWGEDALEFNPDRWGPERVGSIKPFMFVPFHAGPRICLGQNLAYTTAQVTLTRLLQRYDIQAKPGFEPQQVGDIVLFSRNGVEVLIRKKSISKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N479</accession>
    <name>A0A9P6N479_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_001320</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000013">
        <property type="protein sequence ID" value="KAG0024563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N479"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019185">
        <property type="term" value="C:snRNA-activating protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001006">
        <property type="term" value="F:RNA polymerase III type 3 promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042795">
        <property type="term" value="P:snRNA transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042796">
        <property type="term" value="P:snRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051575">
        <property type="entry name" value="Myb-like_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46621">
        <property type="entry name" value="SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46621:SF1">
        <property type="entry name" value="SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH myb-type" evidence="7">
        <location>
            <begin position="706"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="6">
        <location>
            <begin position="706"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="53"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="224"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="277"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="557"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="631"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="558"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="575"/>
            <end position="585"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0024563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="775" mass="85050" checksum="E5C0993E7E85EE58" modified="2023-09-13" version="1">MCESSCANEEFQRVPIVVTSAEHDLKIQDSPEQRLQFNLMSWSSFEVENEWASDVSASDSDANTRDRSIYSSGPEYEPAIASTSTGISCRSREKKRKLEHEWDIDPYEYGWDSSSETGGFSSPSAFEVASTSVKAQPTPGLYASSPLGDFVGKLDDPRIWSATDAHKPPKLVHPYNENNGRSSTLEDAPIQSLVCALGQSQLGSDKLDGIDNEEMVMRYTTLVDGTSETPKETSKKQRKKCAPRNKATDKMSIRSGRWTAAEDKALIQGVFDYLSSRGLEPQPPSHLPTEQELDTSERTAQDASAILTIANLQSARPSVGHLVERQSQCLCWGDSSHEHDCLGVAGSDVELLDSIVDVSYVANGEDTFEDIAATSNYLELNPHSDSILPHHRRGVHHWAMSPALFSPLVPPQLREISFVPILTGHTGANRQIDVFWQPHFQLNPVSHFHGGSCETTNIGFQQLGRRSQRLSRLPSPSKNPGLGISDGSPLFDGTITQISCPLGYQQPQQELFPFNRYDKNSYPQQHHYQHQGYCGYQGFFGHNHSHPSTVLSLPITPPFSASPSASPQTSVPEPTMSSDTSSPQVPFTTCDPHAFDCSSNTTSKNIHLVKLITARDVPGGDTDHGVQVVSRQTTKSVASGPVKPCSTSPAFTPLPASQRETPKTREAYITAISRAMSLCPWSVIASHVVPGRTGVQAQARWSEALDPQVKKGPWTAEEDALLLKGVQQSEKCWIWIADGIPGRTQRQCRTRWVQISSRQERNAAAMARATGKTGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4B3</accession>
    <name>A0A9P6N4B3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_004766</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000024">
        <property type="protein sequence ID" value="KAG0024252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N4B3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010945">
        <property type="term" value="F:coenzyme A diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03426">
        <property type="entry name" value="NUDIX_CoAse_Nudt7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045121">
        <property type="entry name" value="CoAse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12992">
        <property type="entry name" value="NUDIX HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12992:SF44">
        <property type="entry name" value="NUDIX HYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="2">
        <location>
            <begin position="85"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="265"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="56"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="274"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0024252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="375" mass="43286" checksum="BB7AC5508AAAB65A" modified="2023-09-13" version="1">MSREISALTTIIDSLGPPRKIKSRGPKFRRASVAIIIRIRPDQNRYSQYSNTRHSQQQQQQQQQQQQQKQQPQLRPIQAIENPESLSEFFAQDWVRTGVPEVLFIERATRKTDRWSGHVALPGGKREEGDEDDQETAARETLEEIGLDLSDMAQFRCLGALDDRELWTSFGRVFLMVLSPFVYIQLLPSTPPLKPQPDEVASVHWQPLSLFLDRLEKPLWTPMTINLSSKLTPRLSRTFLRGLFGTMSLHSIEMPYKPEFVLRTTQQQERNNLSSSRGPGSPTSSVASSVIVDYEPDWDPDHRPLKLWGLTLQMMADLLELKDGPIQLDIRQKVWDSKRMRKRLDAGFLPGFSQADMHFWVRALLKFHSWQGTEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4L0</accession>
    <name>A0A9P6N4L0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Duf1682 domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_000024</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000001">
        <property type="protein sequence ID" value="KAG0024896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N4L0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032469">
        <property type="term" value="P:endoplasmic reticulum calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012879">
        <property type="entry name" value="CCDC47"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12883">
        <property type="entry name" value="ADIPOCYTE-SPECIFIC PROTEIN 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12883:SF0">
        <property type="entry name" value="PAT COMPLEX SUBUNIT CCDC47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07946">
        <property type="entry name" value="CCDC47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="42"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="312"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="312"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="340"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0024896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="352" mass="39749" checksum="E44512F6A6C05FA1" modified="2023-09-13" version="1">MNFIRIVTRLLDTDHPSPSLAILDSITNVAIDELREKYSYEVLYLSIILLILVTYWVGKRHNEVLAKTTMAVMLPLFRSNFARVGDNGAELAIDSPHEYIIYLTGRRHVATVHGLIKMRPRQDLIRTLFTLLSTPAQDICTLNVTMNPNEYSDGVFAIVPKSTGTAIRNKHYDLTTFTKASSQKALDSSLITLTESSELTDAIVPLVSEKLNKAVKWLDYFIVSDQPTHKPDTVPTQPHAKRISLSFRLPNAKDAREILPLVEALVACLDGLPRGCQVSSVTKTKISKAREEALKEIGKKVQAERARELEEKRLKEKREQEKNLSPEAQRKLAAKEEKKALKKRQKQVTKKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4S5</accession>
    <name>A0A9P6N4S5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Adhesin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_009006</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000051">
        <property type="protein sequence ID" value="KAG0023573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N4S5"/>
    <dbReference type="OrthoDB" id="2406635at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="181"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="42"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="158"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0023573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="487" mass="53417" checksum="FE4A5746830389E4" modified="2023-09-13" version="1">MPFPNDKKGELPQVFDAEDERIAFGRQSPYATPTIPSQSIEPTAQTAPAATSTSAPVPQPSTPSSFPTERPSAPQALPHSQNEHSYNSQDGHVAVDVPPPAYEDVVQRRQSRPPQQHYQPDEDNNTSPSAPLLGRSPTADYSSIPATSNTPITRAAPSHSPSISGSSTSDDSERPRRFNKFWFWFIIIIIVLLLIGEKDENMSEKCRNPASRTLADYLISPDYTDFTVTMANMPSYIVVDQGGSDELDEGMTRISAIATASDQEDLQNIGHEIKHEQYGRAVKASFTHSSNKVAPECLETMLRITFPTSMEKLMRLRLRVNEGNITINLLEPNKTLPLQYLESTVITGHNYIRADVAQSTKVGGTKGTLKGEIVVRRELSANLIDGDVSLNLIQSPGVLVSSKINVVNGDIKVGMDENYEGSFKLKTTNGSVRVMNADPRKTRIKSSNKNAIEGWHTINGKEPVVSSDLVLSSLHGEATLSLRRIEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N508</accession>
    <name>A0A9P6N508_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_008223</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000044">
        <property type="protein sequence ID" value="KAG0023746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N508"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000922">
        <property type="term" value="C:spindle pole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005516">
        <property type="term" value="F:calmodulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051295">
        <property type="term" value="P:establishment of meiotic spindle localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007051">
        <property type="term" value="P:spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23767">
        <property type="entry name" value="IQCD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051185">
        <property type="entry name" value="ASPM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22706">
        <property type="entry name" value="ASSEMBLY FACTOR FOR SPINDLE MICROTUBULES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22706:SF1">
        <property type="entry name" value="ASSEMBLY FACTOR FOR SPINDLE MICROTUBULES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00612">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00015">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0112">Calmodulin-binding</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="55"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="119"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="558"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="626"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="476"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="770"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="32"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="55"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="78"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="119"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="179"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="564"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="658"/>
            <end position="670"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0023746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="804" mass="89889" checksum="D239C17BA5D1A3EB" modified="2023-09-13" version="1">MSARIKGLFSSKKKKDGRSDSKSYPKGVSKAASVSTKSRTVSIGSFASSTSAFEFQRDGTSQGDTIDAIKKEEVQHQTTTASDASKTSTSSSTATIDEGGAMTTDIAMAKLALANNDNSTTTTAQIPSSPSVSKQQKEAEAPLVSTADVPVNYSEKEMEKETITISPQSLEPSGPRESLVNTSHLSASGNRGNVSGERDRSNRSIIPAVYFDERETSRISQRQDGSFVEHRSYNSTSQLSPEQNVNDGIYLNSTTEFFPVDDQDEQVYLEQYSDEIDEFPALQIKVSKIQKQVREMRKFMRGLVQLQIEQYEPATILIQAWWRGCLVRQELKKQRVFSWHRNPKRKVKPIKYLTRAELHQSCERISTPKASLLVSEELGADKETIAVVKLQAAFRSCLVRKRVQAYRNGMRAATIIQSRWRGYWTRNLDTRLGVEQLRFRNLKVQKAFSRVSIKLQYLQGRILALEENSLPMHEAQEMMQKELEDMGDQMDTLKQDLEQSFKQLDEQVSEEKEQTTIELRGLTERIQKLEDEIKSLRSSNTSIEKQVKSLTLELPANSNLDADKSEEDDDDYEVEYDEDGNRIEKPPKKTVKRASLQDQLMEQSIGAGPRRSSTTRAAMDTIMSSSPTQMVESPVPMPRRAHRGSISSIHSQGHARTHSLNSQPPASPSQGFPRAFSASYSPTITNAALIPDGSGGAFANGVRPHSIQYPGANNNSNNPARPLTMDPNQLFRFHAAANQYIPVSPSSGPAPTDAKKYVSVDDFEYMQAEVDTLRLNNDRLEGMVRELTMRLNTLTSNMGQFYPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N595</accession>
    <name>A0A9P6N595_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_007277</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000037">
        <property type="protein sequence ID" value="KAG0023915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N595"/>
    <dbReference type="OrthoDB" id="10021397at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1720.10:FF:000013">
        <property type="entry name" value="Related to multidrug resistance proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF191">
        <property type="entry name" value="VACUOLAR BASIC AMINO ACID TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01036">
        <property type="entry name" value="TCRTETB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="64"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="102"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="132"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="157"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="190"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="220"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="258"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="283"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="327"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="367"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="392"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="419"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="458"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="526"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="67"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="13"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="25"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0023915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="566" mass="61881" checksum="1A6FEC8FA29DFC4F" modified="2023-09-13" version="1">MDSAGQKYELDEPASASSTSIPIADSKEEAMSDIGRKGDESSVTVSESPNQDIVVFHKPPTRQFVLIMIALSLSVFLASLDQIIVSTAIPAITREYNSLGDISWLGTAYLMTATAFQPLYGKFSDIFGRKATMLFANTIFLGGSCIAGWATSMNMLIAGRGVAGVGAGGLMAMVFIILSDMLDMRERGKYLGFIGAIFSFSSVVGPLLGGAFTDHVTWRWSFWINIPFVVISIIFITVNLNLPTPKGTLADKLRRIDYVGAILLMVAVILILLPLSWGGNKYAWDSGIVIGLLCAGFAVGGIFVLAEWKIAKEPIVPIHLFKIRNLWSTYGSLFFSGMAFFGILFYLPIYFQVVKNESATNGGLETVPFVFGIVITSISSGLWVVKKGTFAFFPMIGNLFFIAGSALCILFKADTQRVVTIFVLLICGMGMGFTMQASTLAVQVAVKPKYMATVTTSVQFIRSLGQVFGVAIVGTVFNNKLVESLKKDFPGDDNILKVTEDYNYIYTYKKESISLIYDCFVYGLHYVFYCGVAFCVLAFISSTFIQHKELKTNANQGKPEMTVEMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N7F8</accession>
    <name>A0A9P6N7F8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">FACT complex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">SPT16</name>
        <name evidence="15" type="ORF">BGZ80_010272</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Component of the FACT complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Chromosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the peptidase M24 family. SPT16 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000007">
        <property type="protein sequence ID" value="KAG0024693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N7F8"/>
    <dbReference type="OrthoDB" id="10251642at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035101">
        <property type="term" value="C:FACT complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031491">
        <property type="term" value="F:nucleosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01091">
        <property type="entry name" value="CDC68-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.210:FF:000001">
        <property type="entry name" value="FACT complex subunit spt16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000017">
        <property type="entry name" value="FACT complex subunit SPT16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.350.10:FF:000006">
        <property type="entry name" value="FACT complex subunit SPT16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.230.10:FF:000005">
        <property type="entry name" value="FACT complex subunit spt16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.210">
        <property type="entry name" value="FACT complex subunit Spt16p/Cdc68p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029148">
        <property type="entry name" value="FACT-SPT16_Nlobe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056595">
        <property type="entry name" value="Fact-SPT16_PH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048969">
        <property type="entry name" value="FACT_SPT16_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013953">
        <property type="entry name" value="FACT_SPT16_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013719">
        <property type="entry name" value="RTT106/SPT16-like_middle_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040258">
        <property type="entry name" value="Spt16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033825">
        <property type="entry name" value="Spt16_M24"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13980">
        <property type="entry name" value="CDC68 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13980:SF15">
        <property type="entry name" value="FACT COMPLEX SUBUNIT SPT16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14826">
        <property type="entry name" value="FACT-Spt16_Nlob"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24824">
        <property type="entry name" value="PH_SPT16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08512">
        <property type="entry name" value="Rttp106-like_middle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08644">
        <property type="entry name" value="SPT16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21091">
        <property type="entry name" value="SPT16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01285">
        <property type="entry name" value="FACT-Spt16_Nlob"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01287">
        <property type="entry name" value="Rtt106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01286">
        <property type="entry name" value="SPT16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 10" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 10" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8 10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3 10" id="KW-0235">DNA replication</keyword>
    <keyword evidence="9 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 10" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="FACT complex subunit SPT16 N-terminal lobe" evidence="12">
        <location>
            <begin position="8"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="FACT complex subunit SPT16 middle" evidence="13">
        <location>
            <begin position="540"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="domain" description="Histone chaperone RTT106/FACT complex subunit SPT16-like middle" evidence="14">
        <location>
            <begin position="811"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="444"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="938"/>
            <end position="1021"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="472"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="967"/>
            <end position="987"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="988"/>
            <end position="1008"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU367052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM01286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM01287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0024693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1021" mass="116923" checksum="480F0F7392AFCFE6" modified="2023-09-13" version="1">MPTTEVTIDARLFHRRARGLVNHWKKSNGSDESFQNVSSLLVVLGNMTDEDNMYQKTTALQIWLFGYELTQTLMLFTPDTLHVVTGGNKAKILESLKTWEGPQFPIEIHARTKDEAHNEEIFQKIVEIITKHGDRVGVFAKDTQTGGFAAAWEAAMGKSQKPIERVDMSSGVAEVFAIKDDEELRSTKMATKLSSLLMKNYFIEEMSQIIDEERKITHEKFAEKTEDVLLDERMFKQLKFPADAAAGNPEWCYTPIIQSGGDYDLKTSAVSNGKELHAGTIICSLGVRYKSYCSNIGRTFLIDPNKTQEKNYNFLLDVQRKILDTMKEGVLIKDVYSRAMDFIRNRRPDLEKKFVKNLGFGTGLEFRESNYLLNGKNTRELQRDMIFNLAVGFQDIENPKATDEKSKKYSLLVIDTIRITTEAPQILTFCDTSFDDISWTFQDPAEEEEEPVKKESPSNQRAAKSAVLNTKFRSEQEEASKDQARKEHQKMLAEQKHSEGLERYGDGGSLKKDNQKSVFRKFESYKRESALPKEVSSLRIIVDQRNDTLVLPIYGLAVPFHISTLQKVTKTDEGEFFYLRLNFITPGQPGKKDDTPFDDPNANFVRALSFRSADGARMSEIYNQILELKKSAVKKESERKEMADIVEQDKLIETKGKRPPRLPDVFARPGLDGKRPGELEIHSNGLRYVSPLRNENKIDILFNNIRHLFFQPCDGELIVLIHCQLKNPIMIGKKKTEHVQFYREASDAQFDETGNRRRKYVYGDEDELASEQEERKRRANLNKEFKQFGEKITEISENRVEVDVPFRDLAFNGVPFRTNVLLKPTQDCLVHLSEAPFLVVTLADVEIVHLERVQFGLKNFDMVFTFKDYFQPPIHINTIPMSQLDNVKDWLDSMDIVFYEGPVNLNWGPIMKTIQEDPAEFYKEGGWSFLAIESDAEESEESASEFEASGSDFDESSSESSYASDASMDDGSEEDDEDEESGEDWDALEEKAKRADDKKYGSSKREADSDSDDDRKKKRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SR76</accession>
    <name>A0A9P6SR76_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HAT C-terminal dimerisation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_008878</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004982">
        <property type="protein sequence ID" value="KAF9991801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SR76"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008906">
        <property type="entry name" value="HATC_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052717">
        <property type="entry name" value="Vacuolar_transposase_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46169">
        <property type="entry name" value="DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46169:SF29">
        <property type="entry name" value="DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05699">
        <property type="entry name" value="Dimer_Tnp_hAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HAT C-terminal dimerisation" evidence="2">
        <location>
            <begin position="88"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9991801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="149" mass="17011" checksum="8B69C0A63E80F258" modified="2023-09-13" version="1" fragment="single">MVRDYWSALYKENYKPSYPSSTSSPEPEHGRLSDKMQSVHSSANTITEQLDDICWDSDVDDADRANFDLALEGVLGKRAHREEDDDDLEKWISLPLVSNLQPLEFWRQYHSQFPALAAMARDILAVPATSASSERVFSKARGFIPYQRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SUX5</accession>
    <name>A0A9P6SUX5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein transport protein sec16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_005405</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Involved in the initiation of assembly of the COPII coat required for the formation of transport vesicles from the endoplasmic reticulum (ER) and the selection of cargo molecules. Also involved in autophagy.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the SEC16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002666">
        <property type="protein sequence ID" value="KAG0005684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SUX5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070971">
        <property type="term" value="C:endoplasmic reticulum exit site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012507">
        <property type="term" value="C:ER to Golgi transport vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070973">
        <property type="term" value="P:protein localization to endoplasmic reticulum exit site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09233">
        <property type="entry name" value="ACE1-Sec16-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.1030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024340">
        <property type="entry name" value="Sec16_CCD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024298">
        <property type="entry name" value="Sec16_Sec23-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13402">
        <property type="entry name" value="RGPR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13402:SF6">
        <property type="entry name" value="SECRETORY 16, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12932">
        <property type="entry name" value="Sec16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12931">
        <property type="entry name" value="TPR_Sec16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0072">Autophagy</keyword>
    <keyword evidence="3 6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 6" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Sec16 central conserved" evidence="9">
        <location>
            <begin position="222"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="Sec16 Sec23-binding" evidence="8">
        <location>
            <begin position="344"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="46"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="193"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="673"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="969"/>
            <end position="1018"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1158"/>
            <end position="1223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="56"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="91"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="201"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1158"/>
            <end position="1185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1186"/>
            <end position="1197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1198"/>
            <end position="1223"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0005684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1223" mass="135622" checksum="655A71F2E39F3666" modified="2023-09-13" version="1" fragment="single">MGPLRNQFGSSSQLLLEACPFPECGGENKPHAKFCSECGRSISTASRSETPLLRSATPSLRSATPSLGHHADFSGHTPGMPGLNRINSYTQEYQQQPEQQQQPEHQQPEAYQGYAQDGQNYQQQDQQQYGYSGEQQAYGQEYGQGYGQGYEQGYEQQYDQNYNPDYSNGEYYDQNQQQYYDQTTGQYVDSYAQQEQVVPEPEPEPEPEEEGIDDPLNRIHGCPLIAFGFGGKIMTTFPRNVQRFDSATNVMVTKRYPGDLQLNHVKDVLPVDKDVSSYPGPLLMDSSVQLKNKKKDVLKLIEDKIKEFEQDHQDSTFDAHRVLIWRLFKEPVNPVRSSASLDVLQDLLRNGDRTGAVRYAMSSNLWAHALVISSCVNKELWKEAVNGFINQELMTGGGEVQANGREALRVLYALFSGQTQNAVNELIPLNLRIPANAGQDDAQPTDGQFVTAESLSMVQPVEEPKVPGASLIQWRDTLIMILSNRTSGDQSAISSLGDMLLKEGWVEAAHICYLLSPQSSVHSGLDAQSNRLVLIGADASPHAIFPFYKNVGAFQKTEIYEFACALRSSGATGGLPFFQAYKLIYIWTLVEWGMFSEAGRYLESVEAIVKSQPKGSPYYNIVFLERLKDITERLTGSSQLAVAGESWFAKKVPKPTIGGIFDALDSKISKFIAGDNDQPKPDVVEPKANAAESGPFANAPALPDLSNIPPRALSRSSNSSRAVNQAIAADGAGRPAGTALEVPNADAYGHAQPTVPYTEAVPQAEFAADPTVGQDQTLSYSGYDQSGQYNAEAYPQTDANAGYDYQNQGYEYDANANQAYDQTYQGGDATGYEGYDQQNQYQEQPEAGQNHQAENLQAQGGYEAQYDVQYSVQYDAQYTAQYDGQQELYDASNVETVATEDVPVSNVSTQAVHGSVRQPANEHGSAVEAEVAAAATAVTSELETTYTQQADGTNYSYAEDANYNGEYQTGERQQGEQAYGEHQQGEQTYGEHQQGEQAYGEHQQGEQAYGEHQQGEQAYAEHQQYDQTYGEQQYDQTYGDQQYNQTYGGDHQYGQNYGEQQYDQTYGEQQYDQTAYQDQSQYQNVEGGDQAVGAEYSDEAYQNQGELQQPLDHSAEVPAQEVPAPESQVLADAPTYEQQNQNGEAAVVAETTAEVTDGQHGDYQYGDYPQGEQGEYQQGAYQQDYQQDHHQQGEHQQGEYQQGEYQQGEYQQGEYQQGEYQQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SVQ0</accession>
    <name>A0A9P6SVQ0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">chitin synthase</fullName>
            <ecNumber evidence="2">2.4.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BGZ80_004802</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.16" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010002406">
        <property type="protein sequence ID" value="KAG0007329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SVQ0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030428">
        <property type="term" value="C:cell septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004100">
        <property type="term" value="F:chitin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006031">
        <property type="term" value="P:chitin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04190">
        <property type="entry name" value="Chitin_synth_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004835">
        <property type="entry name" value="Chitin_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914:SF16">
        <property type="entry name" value="CHITIN SYNTHASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03142">
        <property type="entry name" value="Chitin_synth_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="6"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="378"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="404"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="432"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="457"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="545"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="559"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="587"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="617"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="643"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="684"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="701"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="712"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="750"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="765"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="825"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="837"/>
            <end position="875"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0007329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="881" mass="96150" checksum="1D92366E1965DE44" modified="2023-09-13" version="1">MGCFASMVILITTLICVGMVIGIKFVMALSFSWFLSYRLTEKPRTILKPKKDGKKGDEEANANGLDMARNTKVGRKNLYTVMLVTCYSEGENSIRTTMNSLANTSYSTKHKLMMVICDGIVIGQGNKMSTPDIVVNMLDISPGCENPKPCSYLAIADGEKQHNMAKVLILMSFFQRVLFADRFTELDFELFNKIHRLMNVWPDQFELCLMVDADTMVKGDSLSYMVTAMQNNQTIMGLCGETKIANKTASWVSAIQVFEYYISHHLGKAFESVFGGVTCLPGCFCMYRIKAPKYDAWVPILANPEVIQEYNQNIVSTLHQKNLLLLGEDRYLTTLMLRTFPKRQMVFVPQAQCKTVVPDTFSVLLSQRRRWINSTIHNLLELVLVTDLCGIAFLSMQFVVLLELIGTVVLPAAILMTIGMIIVAIANGHFSVLPLVMIITIVGLPAVLIVLTTRKWIYVLYMLIYVLSIPIWNFVLPLYSFWHFDDFSWGETRKVANQKRKSGQDHGDAEGVFESGSIIMRKWEEWEKERLKAMGYRIQKRYSADRGINDLPPPAASIPSGTPDSLKSPSKKLQKTGSASNARSIVPSASAAASTPSLGSTLGGGRGNGSVRANGASGMSQRQVSNHAMPASTPNLISRPQRPRPPPNTMPRPPPPGSMGPGPRGDGQVFEMGPMGSLHSRPVMSSSGPSMNGSRPPPNSGPGGPIGLEGPGRLEARHSIHGEPGIRPMGPPRPMMRPPMMGGGGGPPGNQLSRQMTYHSQGFPGGPPGRPRPPQQSFSGPVLVNHQVSAPPTHMYPNIQQPPPQQQQQGSGGVPYPRPPPPAASSPQQLLPPQQQNQTQLMADQGRQSRLSDISGQTAVSSNRRSAASQGSGTALTGGDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SVR8</accession>
    <name>A0A9P6SVR8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_004921</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002461">
        <property type="protein sequence ID" value="KAG0007227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SVR8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0007227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="334" mass="37180" checksum="C6AB6B6D4190F465" modified="2023-09-13" version="1">MVGLDSILGYVGFISTLVGWFPTNPDQGQVRIKYWAGRDGWNNGFELKESGGELPKVDIRSTSNEWVGHGTMALQWIGSNDQRQVDVDMSKNQEINYLTFTHDGYDATCLALIGWTPNESIPNAERRKGYIIGDIFRLCGWAWNHSGQSVRIANTNKYQDVNCGWMVADKNGRDGFVGLLNINLDVMGEHFIGDYKGKDLCFWGVGMASGRYPRPKKRSLHSPDEHAAAFGNQVRVHKSLSAIELCDSPTSWGSSFFSIEEGVFCDMSTKTKVPVCKAGETEGCFVYERPVVNGRGVYSTKRNVGIRGSTVKYNATYFVTRDENGRVLDDGKGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SVU5</accession>
    <name>A0A9P6SVU5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Iso-1-cytochrome c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">CYC1</name>
        <name evidence="13" type="ORF">BGZ80_004844</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="11">Binds 1 heme group per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the cytochrome c family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002426">
        <property type="protein sequence ID" value="KAG0007292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SVU5"/>
    <dbReference type="OrthoDB" id="449280at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.760.10:FF:000001">
        <property type="entry name" value="Cytochrome c iso-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="entry name" value="Cytochrome c-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002327">
        <property type="entry name" value="Cyt_c_1A/1B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11961">
        <property type="entry name" value="CYTOCHROME C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00034">
        <property type="entry name" value="Cytochrom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00604">
        <property type="entry name" value="CYTCHRMECIAB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="Cytochrome c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4 9 11" id="KW-0349">Heme</keyword>
    <keyword evidence="8 9 11" id="KW-0408">Iron</keyword>
    <keyword evidence="6 9 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Cytochrome c" evidence="12">
        <location>
            <begin position="6"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0007292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="107" mass="11748" checksum="D2C3DA72D09D254C" modified="2023-09-13" version="1">MPFATGDAVAGAKLFKTRCAQCHTTEAGGANKVGPNLHGIFGRKSGQAAGYSYTEANKNKGVTWTEETMFEYLENPKKYIPGTKMAFNGFKKDKERNDVITYLKAEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SX59</accession>
    <name>A0A9P6SX59_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_002346</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001575">
        <property type="protein sequence ID" value="KAG0009481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SX59"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0009481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="238" mass="25752" checksum="9344832E6A7B9BE9" modified="2023-09-13" version="1">MGTRYSEVWPTTMPAPDGPRLVIGTQTSSLRLDTLGMGSVGGSKTSFQLTTADDSKAVRIFLDLESVGSAFDLARDGDAWTVSRGIFFTNCDSCVFTLVNFDQSQHGSEAAAGSMFKAIAMGVIKEGENAKLDLSSPAFLIEPDFETLLSTLKECRRQCGDTKIASTFDAMIGLFSPDTNSIPIIGNRQLNSELEILAKDMFAGSLVWRRWQQRHFGVLNAILAVTSAPPLKKSVNAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SX67</accession>
    <name>A0A9P6SX67_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Copper transport protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_002331</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001570">
        <property type="protein sequence ID" value="KAG0009501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SX67"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005375">
        <property type="term" value="F:copper ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007274">
        <property type="entry name" value="Cop_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12483:SF119">
        <property type="entry name" value="COPPER TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12483">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 31 COPPER TRANSPORTERS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04145">
        <property type="entry name" value="Ctr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0186">Copper</keyword>
    <keyword evidence="4" id="KW-0187">Copper transport</keyword>
    <keyword evidence="4" id="KW-0406">Ion transport</keyword>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="68"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="162"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0009501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="216" mass="24070" checksum="B79A9890B507E639" modified="2023-09-13" version="1">MSQCATWKSMCSASSDTATILSFQSSEYCASGVGSPEMNPPSMRMFFHFGFEDYILFEKWVPRNRGQYVGSWFALFFLTIFFQTIQTYHSNLEVQWAEELAQANEVAKSDSSMSLTNGQPKVHAGSILLHWIHLWRQPWSLNEVKQNVLRAVLTFMETTLGYALMLVTMTFNVPLFFAVIAGLTVGSVLFSRQRSITVLKPNGNNSSAGTGCAGCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SX86</accession>
    <name>A0A9P6SX86_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">RTA1-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_002569</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001638">
        <property type="protein sequence ID" value="KAG0009264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SX86"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007568">
        <property type="entry name" value="RTA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465">
        <property type="entry name" value="PROTEIN RTA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465:SF1">
        <property type="entry name" value="PROTEIN RTA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04479">
        <property type="entry name" value="RTA1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040301462" description="RTA1-domain-containing protein" evidence="6">
        <location>
            <begin position="26"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="108"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="156"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="202"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="250"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="291"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0009264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="356" mass="39441" checksum="1B3CF8134C041EAA" modified="2023-09-13" version="1">MTNQYARGAFLILTQALFLWGKVQAQSSSNGTTSMGSKRNSILSYDPSKAGNTIFGVVYLILGITYLYYIFRHKNKWALCLPIGAIASSIGFFMRLTLDPDNFELTKFAAQQLFVVVSPSAFLAFNYMLYGRFITAIDPKFGNDTKSGSKMEKSQFSFIPPLIVGRTFVISDIVTFLIQCGAGGMQAAGNKDASLASLGDKLFLIGVSVQGISYLVFTLLLTVAFIRLIDDRKRNYPNQLQKGWTGLDKQTLMVVSGLYFSSIFIIIRSVYRIIEFKQGYAGYLISHEIYLFILDAAPLVFAIGVWAFVWPTVLLGKIAAKTREGQQITSIDVGSSRMESSTSSKSEWLSLLALME</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXI3</accession>
    <name>A0A9P6SXI3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pyrimidine 5-nucleotidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_001795</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001418">
        <property type="protein sequence ID" value="KAG0010089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXI3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008252">
        <property type="term" value="F:nucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009166">
        <property type="term" value="P:nucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006206">
        <property type="term" value="P:pyrimidine nucleobase metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052791">
        <property type="entry name" value="SSM1_domain"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47438">
        <property type="entry name" value="PHOSPHATE METABOLISM PROTEIN 8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47438:SF1">
        <property type="entry name" value="PHOSPHATE METABOLISM PROTEIN 8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0010089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="165" mass="18466" checksum="9623280B2A77A1C4" modified="2023-09-13" version="1">MISSGATIDIRDYDNKVDGALPLETLLNENQALRSMIHSMEVGKKWLFTNAGESHAKRVIKILGLEGLFDGITFCNYLERQFVCKPDKKAFEKAMVQAGVLSPDLCYFVDDSAANIEMATKIGWTTVHVNEEPSGSALLGNFQIRSIMELPNVMPQFWDHRRGSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXV5</accession>
    <name>A0A9P6SXV5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_002136</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RPAP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001518">
        <property type="protein sequence ID" value="KAG0009714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="348201at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039913">
        <property type="entry name" value="RPAP1/Rba50"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013929">
        <property type="entry name" value="RPAP1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013930">
        <property type="entry name" value="RPAP1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057989">
        <property type="entry name" value="TPR_RPAP1/MINIYO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21483">
        <property type="entry name" value="RNA POLYMERASE II-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21483:SF18">
        <property type="entry name" value="RNA POLYMERASE II-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08620">
        <property type="entry name" value="RPAP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08621">
        <property type="entry name" value="RPAP1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25766">
        <property type="entry name" value="TPR_RPAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="RPAP1 N-terminal" evidence="7">
        <location>
            <begin position="321"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="RPAP1 C-terminal" evidence="6">
        <location>
            <begin position="467"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="domain" description="RPAP1/MINIYO-like TPR repeats" evidence="8">
        <location>
            <begin position="1372"/>
            <end position="1460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="53"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="217"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1260"/>
            <end position="1298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1471"/>
            <end position="1495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1669"/>
            <end position="1688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="7"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="218"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1284"/>
            <end position="1298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08620"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF25766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0009714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1688" mass="186994" checksum="BBAA0057D37AFAFE" modified="2023-09-13" version="1">MNPGSTNDEKRRMEHESVIRQRRQAPETEDDLLAMQEEFLKANDRPAAVAVRVKPPTVAGRTSLTKTTVQDEDDDDMPPPLEKDVVSLNSDELPLSPPTVSASSSKLRAGSRFLQDRANKGPRTHFQVPTRERFEINLDDDIDGNGPSSEVETEEETRRRLNNAGPSMGQILHEVLEKPAREVVAPQVATTTPGSLVPNTQSTKGFKGKSLFAKRLAEAQSGASTTQSTTEPTSNTTSAQSQDRPVSATYKSFMSRANNANNPKKDVVSFSNLDDLVPLKPITKTSAMPTNIDRHETDKKKTPLHSVLKKSPDTPQSTLMEQIDEENRRKLSAMSQEEIEQERAELLRNLNPELVKKLMKRNNVQRRVSFSEGVKVEDKVVNIHDVRIPHNDSAFQAKRHEEEEGDHPLALRKKYFADVPSEPEKLEWMGIESENMDDGARHTPGKSVAPGPQPYTVSEADPPAAHYRFDFSGMIIEGKDTPIHMGLHHHGMDPTKAGYTLSELLHLIRSTVPSQRILPLNIVAKVLQNCRKSDYASFEVRAGILRWLIDTLRAPVYIRAALDDKTDSGIVAAVNALYAWITPQEKLGEQEDIWESLDHLERGYERIYHGFKYQSITRFANMELKPDSLQASQEQGTETEDTIAAHAILASKDPVDGLLAMNIIPRLRYLLSVCQLPAFTNAQILDILLTVARSNAGAPKKIFECEGLISVLVRQYGAITWPSEKSNLELSCTVKAISILDVVVRSSKKIASAMIEEGHFEPLLRFLVLTPEATVENKSSFSIQTQVLKLFRSLAAYGLYCNVLGDNLQSHLIQDLAQSITERSKPDLVPTVKSFLSRKLSMLFQLLTAWTHAAADVHRTIPEHSLCWAQAAAFMDLALEGVSHWKQEGQMVGFDIDHILLVSSAVRYICTWARYLPTNPPDNEQILVRVWEALRLKDFIKSDTFSIVHEHLSSIIQAVPELTEAPLPHVGVTMSNPTALSRIASNLLEVSLGCEYLNSHLTTMFYLARLTSAPAFILEDVVDTLVSESVFGMVEKVTKFELAIQDQIPTTLPPWMAFISRHGVYFISHWLLAMDVLVYRQDPDNSSPIKLTFFPLFQVTALSLLQIILPGDEFLSHEVLIKNLFNPRVLDKLLSHNTDQIIVVKRILEPLYLQCFVKSDVDLKQSHGFWSRDGRGIKSLTVDYGRITGQPLFHWLSHPIELLFKSKLTYVEESGTLIAATSVAHCTFDFIYSLLQTLDGISFELVYMAILNILSLEGEKEPPEGNEDEDGFDRAPGSQREVGEEAEGGEEEEEEEDGFMDAEVDSAINKLLDHFSTRGDCSLVHDDSQGQPILSEKTLSLLTAPLPFSQFMKNFMENSFTTGSLLRYQPTAARLLFPAMAISSELQLLIWQESFNFLGSITTSWEELDAGTLRSLLSDDLGNVTSEVLKHYLKAVVSGRVIKQRNPALYWIAVHHLARVAFGPIPMPLPSRGGSRSRVAPPSEDSNQGREGDVGLSAEDAAALEERCAIAKAIITGAKSDELIRDWIQYDGRNYEQSPSTVSALSKSSAALNGAGSTSTGLSSSTSAPVIVDTNVAANVSELGSPTSPMTKSPSRPLSLLSNSASFPVVGSSDYLNYDNILAPPECFRERRQLMIAARKTWIKGVVDESGLARVEDAIQAMAPVAQVTHGGGGASTKPGSIYGGPRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYG5</accession>
    <name>A0A9P6SYG5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_000413</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001084">
        <property type="protein sequence ID" value="KAG0011808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYG5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0011808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="359" mass="40951" checksum="DCBF907C2B5FA62A" modified="2023-09-13" version="1">MEAIGKCQGLASLWLSNSILYSEGVRTLLVACANIGKATEREGEDRNGIRENRTGGLAKLHLEDLSIRECSEDVFSGSTPFPHLEHLDIQKIRGIAPKDVLKLLQRCPNLKSFCWRDVFTRESFLIDQWVKHVESGAWSRLTCLDVQGEEFHDEGLSCVFKNLQSPLEKLMVRETGFGPMAFEALITTKRHYCHIRALDLSLCMDTTSSMIQKIMTKMPALVYFSANRLFVTDILGTSREDQNDNDDDQEWVCKNLRTLKLCIDMGVGSDPNTLEYEERQRQVYSRLSELEFLETLEVGNLLFLRDTEVQRLDSRPNAGFGQLLSLKRLKVVSIKQGHSLALKDIELMMAKKMEDEPKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYL0</accession>
    <name>A0A9P6SYL0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Vhs domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_000249</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">May play a role in the regulation of membrane traffic through the trans-Golgi network.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
            <location evidence="1">trans-Golgi network</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001045">
        <property type="protein sequence ID" value="KAG0012039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYL0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006895">
        <property type="term" value="P:Golgi to endosome transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006896">
        <property type="term" value="P:Golgi to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043328">
        <property type="term" value="P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14235">
        <property type="entry name" value="GAT_GGA_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.90:FF:000008">
        <property type="entry name" value="VHS domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052653">
        <property type="entry name" value="ARF-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008152">
        <property type="entry name" value="Clathrin_a/b/g-adaptin_app_Ig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013041">
        <property type="entry name" value="Clathrin_app_Ig-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008153">
        <property type="entry name" value="GAE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004152">
        <property type="entry name" value="GAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038425">
        <property type="entry name" value="GAT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002014">
        <property type="entry name" value="VHS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47180">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-BINDING PROTEIN GGA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47180:SF1">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-BINDING PROTEIN GGA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02883">
        <property type="entry name" value="Alpha_adaptinC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03127">
        <property type="entry name" value="GAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00790">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00809">
        <property type="entry name" value="Alpha_adaptinC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00288">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49348">
        <property type="entry name" value="Clathrin adaptor appendage domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89009">
        <property type="entry name" value="GAT-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50180">
        <property type="entry name" value="GAE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50909">
        <property type="entry name" value="GAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50179">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="VHS" evidence="7">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="GAT" evidence="9">
        <location>
            <begin position="120"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="GAE" evidence="8">
        <location>
            <begin position="419"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="258"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="361"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="258"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="326"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="374"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="384"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00053552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0012039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="537" mass="58458" checksum="D69FAE4EF380C0DF" modified="2023-09-13" version="1">MHVAMLALELLDNCVKNCGYPFHLQIATKEFLNELVRKFPERPLSVPTPVQNKILEMIQEWYQTLCKSSRYKEDLVHIKDMHRLLSFKGYRFPQVKGDSASVLNPVAALKSPAELEEEDRAAQAAKLQELIRRGRPEDVIAANELVKKMTGYEQEEKPDYAEESLTELEKISQKATLLTEMLNDVKPGEIIGRGDIFEELLNTCKAAQPKIQKFISEGEDDANMEKMLHINDIINSVIEQYNQVKKGNLVKAAIPNLSSESDAGSSTAPSRSEPSLIDLVDFGGSDNSPQPAAPAPKTTGNLMDDLMNLSFNDGPPPAWGAAGSINLGQSTAPSGSGFNSNRSSTVAPPPGYSAFSSISGSGTGSPAFGGSPLMAQSTLQSSRPTTPGYQPQTQQQSLSADDSAFGDFNFVSNTGAAPSGPKSVVLLNKNGLLIELDVEYPNNDPSSIQMTAYFSNSLSKPMSAMTFRVAVPKSLQLQLNPQSSQVVGAFSKRAMSQSMSINNPTRQQPVRIRYHVSYVLEGQTIEEQGEFNQFPSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYL7</accession>
    <name>A0A9P6SYL7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_000409</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001083">
        <property type="protein sequence ID" value="KAG0011815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYL7"/>
    <dbReference type="OrthoDB" id="2413238at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="152"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="226"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0011815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="369" mass="41054" checksum="DFB5E0EB96B4FF86" modified="2023-09-13" version="1">MTTKVMKYLTYRADTFAHQRSFAINFLPFKSQSSILQYHNFTKTRIHADTGKAAASAIATSVATSNRAADEEPDSSVRNRDSFVDDNKNLACHSNSRMRKFYLNDCDVNGRNQKTGYNNNGKESIQSCNDNDTTPGWKFRSLKNRSCSKNTSLPSSSSSSPPSSSSSVHGCRWSPISPMDPLVWPSSVSAFPVSMRSTEPTETPIYDCPHYMAALIGPTDSGYSSEEEHSVDVDDAKDKDSDEPEAEWTLPFYMEGDVEQDKNDEYVEHGHQTSNGEEETAIVTMASIASFVSSAFSFESKESTKASDDDDNPSFKVVTRLRQKLERTEHEARLAKANLSDLVLSQIGGQHGWWPLSFAYGQDGVYSLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYQ9</accession>
    <name>A0A9P6SYQ9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_011807</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000999">
        <property type="protein sequence ID" value="KAG0012340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYQ9"/>
    <dbReference type="OrthoDB" id="10039976at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039143">
        <property type="entry name" value="GNPNAT1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13355:SF15">
        <property type="entry name" value="GCN5-RELATED N-ACETYLTRANSFERASE 3, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13355">
        <property type="entry name" value="GLUCOSAMINE 6-PHOSPHATE N-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="94"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0012340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="233" mass="25383" checksum="215022E08F517393" modified="2023-09-13" version="1">MTITFFAVDPQYSDGTDLSLIPPPHSQPSTSTTIVIWRLVAIANNVTPKGLYLPIEKSLVVDAFDILFPQLSTSCTAGPDLQRIETCLANPDTFTLFLATETTETIFFKAVPRNETDTVAASSVAGDAGDVPSSPPRISFKISKIVGCLTLITLKLLMKSRAHIEDLVVSNDCRGQGIGRGLMKRALHDAVHIRGCEIVDLTSRPDRIQARALYESLGFKLRDTGSFRYDAPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYZ6</accession>
    <name>A0A9P6SYZ6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidase s41 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_000463</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001099">
        <property type="protein sequence ID" value="KAG0011717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYZ6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052766">
        <property type="entry name" value="S41A_metabolite_peptidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37049">
        <property type="entry name" value="PEPTIDASE S41 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37049:SF4">
        <property type="entry name" value="RHODANESE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040133540" description="Peptidase s41 family protein" evidence="2">
        <location>
            <begin position="25"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0011717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="642" mass="70300" checksum="C5D172CDFE57F325" modified="2023-09-13" version="1">MVSPSLRGLAASAYLIASIALSTAAPIRKKDACGILGATNATDITYDLVAACYKAIPFDSTIASETTGSVVDIFNDYYVFRDSALTPDLQMPFTSAPVDIVKVLETIGSTNYARDLDFHTDIALAIASLHDAHASYNVDCYSAYLFEQPLVLYAPVINGQQSVRVLNDFLGRDISDCEITTIDGNPALPHLQDFADSLSLSKDAGARLNAAIGSQVYDASKNDFVYNSGQFSQRAALPENPTITYELQCSNSASTMTIKDRWYVWPNTQVKFDSVHSYLKNVCKTTPPKNGTPSKRELSSPVKKRSTPAFKKSSFYDAASATIPPKRTSDLSNAEMLGAGNATAFYQLQNPSDVGVIVVHTMDVDYEWNELTFIADGLSEFNRRNISKIIFDFQNNGGGSVDFASTIVQLFFPNTGPLDKILPQDLRVDASIQAVSKRVFNTTGSLYDATNYVDFATKERYTSDGLFLNPVTITRNGRSTLFTEHTGISTTDLQDSAYTKFIQDFPWTNNAANIRILSDGRCGSSCALTTNYLHDLYDVSTYSIGGIRGEELSFFSFAGGAVSDLTTVIGVYNSGDVPSPLSPLPYNGDLRFPLVEVYARNSDVPLEYDYSKYPADTHLNFDSENARSRDVMWTQVAANAWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZ06</accession>
    <name>A0A9P6SZ06_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_000425</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001088">
        <property type="protein sequence ID" value="KAG0011783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZ06"/>
    <dbReference type="OrthoDB" id="277802at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005689">
        <property type="term" value="C:U12-type spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097157">
        <property type="term" value="F:pre-mRNA intronic binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030626">
        <property type="term" value="F:U12 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12246">
        <property type="entry name" value="RRM1_U1A_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000039">
        <property type="entry name" value="U1 small nuclear ribonucleoprotein A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045164">
        <property type="entry name" value="RBM41/RNPC3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16105">
        <property type="entry name" value="RNA-BINDING REGION-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16105:SF0">
        <property type="entry name" value="RNA-BINDING REGION-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="12"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0011783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="141" mass="15482" checksum="887E69E6708BE13E" modified="2023-09-13" version="1">MASTNPTIDPNQTIYVRNLNEKIKKNELKRSLYCLFSAYGKVISIVASKTKRDRGQAFIAFSDIVSATAALRGLQGFTFYGKSMEIQYAKTKSHAIAKLDGTFKQAPMKKLGAGSADQTVSLSVAKREREADSDSDSEMSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZ61</accession>
    <name>A0A9P6SZ61_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF1772-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_011411</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000914">
        <property type="protein sequence ID" value="KAG0012935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZ61"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013901">
        <property type="entry name" value="Anthrone_oxy"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36535:SF1">
        <property type="entry name" value="DUF1772 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36535">
        <property type="entry name" value="YALI0E30327P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08592">
        <property type="entry name" value="Anthrone_oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0012935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="119" mass="13167" checksum="D05E67CAB5EBC6D2" modified="2023-09-13" version="1">MPALRKISNENALPVWAHSYNIGKKLQVGFIMTSLVTGVSVYSRTENPYYLAGSLIMTSIIPYTLAFIMPVNNTLLSILDGKKSDGNIERLLTKWDQLHFGRTLMGVAAFGLVLYGELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZ82</accession>
    <name>A0A9P6SZ82_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HTH CENPB-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_011145</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000860">
        <property type="protein sequence ID" value="KAG0013340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZ82"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006600">
        <property type="entry name" value="HTH_CenpB_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007889">
        <property type="entry name" value="HTH_Psq"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04218">
        <property type="entry name" value="CENP-B_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51253">
        <property type="entry name" value="HTH_CENPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH CENPB-type" evidence="4">
        <location>
            <begin position="118"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="26"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="352"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="36"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="353"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0013340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="432" mass="49211" checksum="DDBCBDE740B0608B" modified="2023-09-13" version="1">MTSYPPTRPSADNSSMFHFVQPNSDMQEADTMASPPESNMQLDMSPGPETTNNGRKEGKYQGRIDITFSKKAAVIRRWKSDPLISKAQLAKECGIPRTTLYGIISRMDKYSSDDESQTRCRSRKPLFPLLEEAAVRWIKYRKTLGVSESDVRSIGIDVLHTMDRLLLAPQPPCKFSPSWIKGFNDRHSKSLETVSVNAVPSSGDKLMDFASTGTRSIEGSDRESIIRNLEGIAKAKFLAWLKNLNEEIGRGSRTAILLLIDLERSPFLDTPTPALEFVTVMVFRSSCSSVPPMRRGIMAEFEGNYNRGPVWNQSTPYVISHNHTELYQELSCNEIFSDGKYKFEGLDYEDDKIEDRDGDKDEDRNENKADSSQASYEIVTNCCRWYFIKRNPTSSSTDFVFRVTQPWVCIMQDDRWADSIFELLQSKYITEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZ91</accession>
    <name>A0A9P6SZ91_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Sulfate transporter family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_000141</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001023">
        <property type="protein sequence ID" value="KAG0012187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZ91"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07042">
        <property type="entry name" value="STAS_SulP_like_sulfate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="entry name" value="STAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052706">
        <property type="entry name" value="Membrane-Transporter-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43310:SF4">
        <property type="entry name" value="AFR304WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43310">
        <property type="entry name" value="SULFATE TRANSPORTER YBAR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SpoIIaa-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040378892" description="Sulfate transporter family protein" evidence="6">
        <location>
            <begin position="19"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="75"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="128"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="8">
        <location>
            <begin position="197"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="7">
        <location>
            <begin position="452"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0012187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="559" mass="62038" checksum="4CDBA4FD86D6E488" modified="2023-09-13" version="1">MLALTFFGILHVPINVPALGVSTGQDNIDINRELVAHGWSNLLSGGVGTVQNYLVYTNSLLFIKSGGDSRVAGVMLAGASLIIFLVGPWIVGYIPVMVVGSLIFHLGLDLVKEALWDTWGLVHPLEYLTITLIVVAMAGFGFVEGIFMGILLACVFFVVTNSLKEGVRYSCTGESAKSTVRRVYRQQKFLRQVGRQIYIFKLQGDMFFGTINKVEKEIQDVFSRRRWEINPIQFLVLDFSLVRNVDFSAAEGFGRIRRAVHAKGVHLVLSGLDEQGEVGKALQMVGVWGAGAGAGLGEGHGHGSTFSHDGSDTQSFPGLSEALEYCENCLLESYYRTRESTLEIAKRKRLLEFANQDDSSSMLSPDSEASRFFAEQIQHSPRKTQIFEAARETLHANERSYPHPINLQQPVPTLLAAFHETRENPTDFFLRLSMYFERRTVLAGTILWRQGGLPTDGLYLVEDGTLRSVQEFQDSGLVRRSVEVILPGTISGEIGLFTGNNRSSTLVSETDSILWGLSQERFQKMVKDDPTLAVEFMRVAMSYSAERLNTMAAYAFNLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZA0</accession>
    <name>A0A9P6SZA0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">S-formylglutathione hydrolase</fullName>
            <ecNumber evidence="2 6">3.1.2.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_011453</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Serine hydrolase involved in the detoxification of formaldehyde.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>S-formylglutathione + H2O = formate + glutathione + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14961"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:57688"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="EC" id="3.1.2.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the esterase D family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.12" evidence="2 6"/>
    <dbReference type="EMBL" id="JAAAID010000921">
        <property type="protein sequence ID" value="KAG0012883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZA0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018738">
        <property type="term" value="F:S-formylglutathione hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046294">
        <property type="term" value="P:formaldehyde catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000801">
        <property type="entry name" value="Esterase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014186">
        <property type="entry name" value="S-formylglutathione_hydrol"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02821">
        <property type="entry name" value="fghA_ester_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10061">
        <property type="entry name" value="S-FORMYLGLUTATHIONE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10061:SF0">
        <property type="entry name" value="S-FORMYLGLUTATHIONE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00756">
        <property type="entry name" value="Esterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0719">Serine esterase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0012883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="282" mass="31209" checksum="C414F516B496F79D" modified="2023-09-13" version="1">MALTLSSQSKHFGGTLSKYTHASTSTKTTMAFNVFVPEGASAQNKVPVLYCLGGLTATEDNFAQKSGFGARASQYGIALVFPDTSPRDVGFPEAGEIADIGYSAGFYLNATKAPWDKNWKMYDYISKELPEVIAANLPIGGHGALTIFLKNQSAYKSVSAFAPILHPTASSWGMYAFPRYLGMDQYTWKQYDTVELIKRLAAEKNLRSDVEFLIDQGTGDQFLNPDRLHTSVLAETIKSLGIDNQFNIRYHDGYDHGYFFISTFINDHIDHHAKAHGLSLKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZQ9</accession>
    <name>A0A9P6SZQ9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">tRNA-splicing endonuclease subunit sen54</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">SEN54</name>
        <name evidence="5" type="ORF">BGZ80_010615</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SEN54 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000758">
        <property type="protein sequence ID" value="KAG0014152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZQ9"/>
    <dbReference type="OrthoDB" id="408683at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000214">
        <property type="term" value="C:tRNA-intron endonuclease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000379">
        <property type="term" value="P:tRNA-type intron splice site recognition and cleavage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024337">
        <property type="entry name" value="tRNA_splic_suSen54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024336">
        <property type="entry name" value="tRNA_splic_suSen54_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21027">
        <property type="entry name" value="TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21027:SF1">
        <property type="entry name" value="TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12928">
        <property type="entry name" value="tRNA_int_end_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="tRNA-splicing endonuclease subunit Sen54 N-terminal" evidence="4">
        <location>
            <begin position="54"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="19"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0014152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="398" mass="44727" checksum="0BF76A553FE6EF43" modified="2023-09-13" version="1">MDAADQDDNDQHPDFRLLLSNSKGQSSSQALPSRDAKSAQDPAAVLEEQYNAYFQILAEERHAAERTFSRAVYEPDLGLFRLTANRGTHFVSMGHTLHGQIYLYPEEALYLVDRGSLLVEHRGTDMTVQQMWNIYLSLPHQQKSQSKGDDQNPTEKDGSPLMDRYLTYAYLKRLGFVVIRPGTYCHESESRTQPPTTTQNQLLTRPLSYLTFLLSAIKNSMFGVWRRHINRIGLGLGNIVNIWARPSNRPLVSNRDHLRYDQILHTLQIIPTVRLAQSSRYSDTEVAPNSKSGIKETVVIDFDVYKPAGTFKKRQPGIPDYHVVVVRAADALPTVNQLKALMAGQFDPAQEATSPLGISVAPEKGKKKKTIDWPKILFAVVSGGQVSFMTIYNVKATP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZW9</accession>
    <name>A0A9P6SZW9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Medium-chain specific acyl-CoA dehydrogenase, mitochondrial</fullName>
            <ecNumber evidence="5">1.3.8.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BGZ80_010583</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 14">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism; mitochondrial fatty acid beta-oxidation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.8.7" evidence="5"/>
    <dbReference type="EMBL" id="JAAAID010000751">
        <property type="protein sequence ID" value="KAG0014213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZW9"/>
    <dbReference type="OrthoDB" id="9988775at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070991">
        <property type="term" value="F:medium-chain fatty acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051793">
        <property type="term" value="P:medium-chain fatty acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.540.10:FF:000010">
        <property type="entry name" value="Medium-chain specific acyl-CoA dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.10:FF:000011">
        <property type="entry name" value="Medium-chain specific acyl-CoA dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.110.10:FF:000007">
        <property type="entry name" value="Medium-chain specific acyl-CoA dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050741">
        <property type="entry name" value="Acyl-CoA_dehydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48083:SF2">
        <property type="entry name" value="MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48083">
        <property type="entry name" value="MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016578">
        <property type="entry name" value="HsaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00072">
        <property type="entry name" value="ACYL_COA_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00073">
        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 14" id="KW-0274">FAD</keyword>
    <keyword evidence="9" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="7 14" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="13" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase N-terminal" evidence="17">
        <location>
            <begin position="40"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="16">
        <location>
            <begin position="155"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase C-terminal" evidence="15">
        <location>
            <begin position="263"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00019125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAG0014213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="417" mass="44972" checksum="5EC4800F896FB7AE" modified="2023-09-13" version="1">MLRSVSSTLRRVAATKAPTQIAVRSFSSSIATHNLSFALSEDQLAIQDLARKFAEDEIIPVAAHHDRTGEYPMEVIRKAWELGLVNTHIPQAYGGPGLGVFDGSLVSEELAYGCSGIQTAIEANGLAEAPLMVAANDEQKKKYLGRMTEEPLMAAYCVTEPGAGSDVAGLQTKAVKKGDKWVINGQKMWITNGGKANWYFVLAKTDANAKTGAAFTGFIVDGNSKGITVGRKEQNMGQRASDTRGITFEDVEVPHENVLGAVGQGFKIAMGAFDITRPLVAAAAVGLARRAMTEATKYAVDRKTMGKHIIDHQAVQFMIADMAIGIEAARMMVWKAGWLKDNGHRNTWEASIAKALASDVAVKSASDAVQVFGGAGFNTEYPVEKLYRDSKIFQIYEGTSQVQRLIIGKGIVDRITK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T017</accession>
    <name>A0A9P6T017_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_010029</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000656">
        <property type="protein sequence ID" value="KAG0015140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T017"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="251"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="259"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0015140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="289" mass="32787" checksum="8F501AE6675B0A64" modified="2023-09-13" version="1">MDSQQQQQQLECIRQNVKEQQSISGVGWNQVNSVNVHRPLIYTQPQQGPVSTQTQEIPQLGRQLIQTASLGSPDQKPEQRLQQYPQPMKIEPMDDDAFDSSLAMVLDDHLTLMDHFNMIPEVEAYSNNPTLTIMPQFKQENSTISSRFPGTVSKSLPSGNVAFGQLAPGSNTTTVNTNNDIKHDLKSNNDLMFYFDTSEILRPESTLNQNPSFTYADHNVLQIKAEPGLLQRQQHQQTQSSMSHYALERQHPFDPSPMLEQQQQPQCDRQSFDHGNSALSADYCYRPLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T089</accession>
    <name>A0A9P6T089_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Anaphase promoting complex subunit 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ANAPC7</name>
        <name evidence="2" type="ORF">BGZ80_009757</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000611">
        <property type="protein sequence ID" value="KAG0015614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T089"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0015614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="413" mass="44695" checksum="1FFB540491A52E3A" modified="2023-09-13" version="1" fragment="single">MEVRNARQHSSQERLAQLQATESLYNAGLFTSALLINIGDQLYVTLTPNAGSVIYQIEDGVNKPSSKPTKKKEYYRKAASLEDSPLPSDISAIDFQNDIIGSNGTGDTGGSQTSAPAAASLGMNIMNTDEEMERTRRQERELAKEKIIKSASNLAARARKAAMESAAKSISGTGVVTRLTNAGPTSIPPVIPQSTTMRKRLASRVDEGRNSNSATDTASKTRLVSAGGDSVAKGKSVRTGVAIDPTGTTDKQYDTDIDYAVSCYKSGDYTTAGKVARKLDSHVLKDMYHYGVCLKQLSKAMYLNKIEKDIVTYEGLVKTYILMERPLEAVDMAKEATKLMPDSAQALAIYGMAIYQAGEQGNEAARDALLKALQMDPGCVQAALCLVMVYENQGLYDDAIQILDQQIDYQPPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0A2</accession>
    <name>A0A9P6T0A2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ATP-dependent RNA helicase eIF4A</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Eukaryotic initiation factor 4A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="primary">TIF1_4</name>
        <name evidence="19" type="ORF">BGZ80_010543</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the DEAD box helicase family. eIF4A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="JAAAID010000743">
        <property type="protein sequence ID" value="KAG0014276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0A2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18046">
        <property type="entry name" value="DEADc_EIF4AII_EIF4AI_DDX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000089">
        <property type="entry name" value="Eukaryotic initiation factor 4A-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000031">
        <property type="entry name" value="Eukaryotic initiation factor 4A-III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044728">
        <property type="entry name" value="EIF4A_DEADc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 15" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 19" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="18">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="16">
        <location>
            <begin position="27"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="17">
        <location>
            <begin position="208"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="14">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAG0014276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="369" mass="41646" checksum="EB8ACA0578B32466" modified="2023-09-13" version="1">MNLSPELLRGIYAYGFERPSTIQQRAILPVIKGHDVIAQAQSGTGKTATFSISALQKLDTSNKQCQALILAPTRELAQQIQKVVIALGDFMKVQCHACIGGTNVREDMKTLSDGVHVVVGTPGRVFDMINRGALKTDHMKMFILDEADEMLSRGFKDQIYDVFQRLPPSTQVVLLSATMPTEVMEVTTKFMRDPVRILVKKDELTLEGIKQFYVAVEKEEWKLDTLCDLYETVTITQAVIFCNTRRKVDWLTEKLTAREFTVSAMHGDMEQGQREVIMKEFRSGSSRVLIATDLLARGIDVQQVSLVINYDLPSNKENYIHRIGRGGRFGRKGVAINFVTADDTRMLREIEQFYSTQILEMPMNVADLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0H5</accession>
    <name>A0A9P6T0H5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Myotubularin phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_009628</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000594">
        <property type="protein sequence ID" value="KAG0015794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0H5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004438">
        <property type="term" value="F:phosphatidylinositol-3-phosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046856">
        <property type="term" value="P:phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030564">
        <property type="entry name" value="Myotubularin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010569">
        <property type="entry name" value="Myotubularin-like_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048994">
        <property type="entry name" value="PH-GRAM_MTMR6-9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10807">
        <property type="entry name" value="MYOTUBULARIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10807:SF128">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-3,5-BISPHOSPHATE 3-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06602">
        <property type="entry name" value="Myotub-related"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21098">
        <property type="entry name" value="PH-GRAM_MTMR6-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51339">
        <property type="entry name" value="PPASE_MYOTUBULARIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myotubularin phosphatase" evidence="5">
        <location>
            <begin position="131"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="529"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="676"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="557"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="581"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="676"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="711"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="758"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphocysteine intermediate" evidence="2">
        <location>
            <position position="331"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="268"/>
            <end position="269"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="331"/>
            <end position="337"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR630564-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR630564-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0015794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="820" mass="90904" checksum="31044F70AD72F392" modified="2023-09-13" version="1">MHRTAVLEKPDAMDLIKVARVDAVQLEKGKSTYIGSLHLMPHHLIFGHPGVEIWISYPTIHSVEKGLPSINNTWPLHIRCYNFVFITLSFQTEKDVTDVYESMQRLTCVNSVEQLYAFVYNPSPPFLTNDGWNIYDPLVEYERMGVVSKNEFWRISDLNQSFTLIYRVTVWLSVDITPKKASITRSSQPMVGLKQNRSIQDEKLIEAIFLTNVPQSSSGHPVYGSTATNLIIDARPTANAVANTAVGAGTENMENYRNCKKVYSGIDNIHVMRDSLNKLVEALQEIDVKGYVSKSALQKSGWLKHIGAIMEGALMIVRNIHICNSHVLVHCSDGWDRTAQLTSVAQVCLDPYYRTLRGFQVLVEKEWCSFGYKFMDRCGHLSNDKNFVALSATNAAANTFANVQSKFYNNKHIRETSPVFQQFLDCVFQIMQQNPTRFEFNEYFLTQLHYHVYSCQFGNFLFNCERERRQYMATTKCSSVWDFINSDKEQYLSKSYQPGADKARGGDGGVLFPDSKPIKYWAKLFGRTDEELNAPDDGPNNPSNERMTPETPGLKPESITTSETEISTDLQVDYDPLGVGSNPTTSQPRSGSRGSDNIRAGASASATSPLEGEDPWQKGSELASKLPAALSGAFGGGFVDSFNRLTTWYSSSSGSGSSSTASFGDDPSAYRELRSSTALTQNRSATVGRSNSYRQRTPLDRELKSIPGIPSSPLHAQSASSSPKHSLSDLTLEHELNQSYPYLNQERDPLRSSSVLKSPTNGSSSSLSRPPSNTRPTAGSNTPPDLTSTLPTSSAGEGGEPVPEPVKGPVKELPHPLFVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0N4</accession>
    <name>A0A9P6T0N4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">GPI inositol-deacylase</fullName>
            <ecNumber evidence="10">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">BST1_2</name>
        <name evidence="13" type="ORF">BGZ80_009414</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the GPI inositol-deacylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="10"/>
    <dbReference type="EMBL" id="JAAAID010000561">
        <property type="protein sequence ID" value="KAG0016142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0N4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050185">
        <property type="term" value="F:phosphatidylinositol deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006505">
        <property type="term" value="P:GPI anchor metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012908">
        <property type="entry name" value="PGAP1-ab_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039529">
        <property type="entry name" value="PGAP1/BST1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056824">
        <property type="entry name" value="PGAP1_TMD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15495:SF7">
        <property type="entry name" value="GPI INOSITOL-DEACYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15495">
        <property type="entry name" value="NEGATIVE REGULATOR OF VESICLE FORMATION-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07819">
        <property type="entry name" value="PGAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25141">
        <property type="entry name" value="PGAP1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25140">
        <property type="entry name" value="PGAP1_TMD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="574"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="675"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="domain" description="GPI inositol-deacylase PGAP1-like alpha/beta" evidence="11">
        <location>
            <begin position="63"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="GPI inositol-deacylase transmembrane" evidence="12">
        <location>
            <begin position="579"/>
            <end position="718"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF25140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0016142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="721" mass="81421" checksum="62B4FCFE6243CCAB" modified="2023-09-13" version="1">MTYMQPTYYRILGFDKDYTDLAGKYGLLLYRDEGDEHPALHPSQLTQTDDRDWSIAKSAKIRPSGVPALFIPGNAGSARQVRSIAKEATRYYNEKIQKGLRAPWSKPIDFFTVDFNEEFSAFHGQLLLDQSRYVNEAIAYILSLYSHSNTAFPRPTSVLIIGHSMGGIVARTLFTKDNFIPGSINTILTIASPHMVPPLALDYTVTSIYDKIEEFWIKGYDTPHVVKQIGIALVEVVDASTPNQVKPLEERMKIFRNHLLWEDSLSTSSISKDSEMVDLSGVSHSFEEGDIWVSPARKPVTISQQTSKAHYHILTIPEHKDLDTLTLLTNLRFGSQEDFSLLLCKDKPQQGSNDKTVTCESDSLSLTAIPGSTRGSTMPLFTGEYFTGHEFRFMSVALSDLEGFRYVVILNKRSVYTDTSFVIVEFKNEASTAEVVHTTAIGLLRSGLTRNKFPENPSLVSTIRLPNVDNSILAYKLKVHGGSCAGAPMERFAPMIRQSSWAINEDKFSVNVANKENGIDINFHGDLPYYDKVLLRANNGIELMFWRDPTCKEPLSFTLTIDTYGSLGKIVIRYRTIVLVFTFMVVILTIRAQIKDWCRNESFKPFGVVLSSLLRTTFWKLSLLLVFVSFIQSLMSKNIVIVSPEAMANGIRVKSRSWISRAWFDNALLGRNETFFWLLLPIFLHVSVGMVAFVWFGLSTIVRAISFFTRLLTRNTSTQHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0V6</accession>
    <name>A0A9P6T0V6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">TEA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_009089</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TEC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000519">
        <property type="protein sequence ID" value="KAG0016595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0V6"/>
    <dbReference type="OrthoDB" id="10006572at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.20.40">
        <property type="entry name" value="TEA/ATTS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000818">
        <property type="entry name" value="TEA/ATTS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038096">
        <property type="entry name" value="TEA/ATTS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050937">
        <property type="entry name" value="TEC1_TEAD_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041086">
        <property type="entry name" value="YBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11834:SF0">
        <property type="entry name" value="PROTEIN SCALLOPED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11834">
        <property type="entry name" value="TRANSCRIPTIONAL ENHANCER FACTOR TEF RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01285">
        <property type="entry name" value="TEA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17725">
        <property type="entry name" value="YBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00065">
        <property type="entry name" value="TEADOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00426">
        <property type="entry name" value="TEA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00554">
        <property type="entry name" value="TEA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51088">
        <property type="entry name" value="TEA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TEA" evidence="10">
        <location>
            <begin position="401"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="TEA" evidence="7">
        <location>
            <begin position="401"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="41"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="179"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="329"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="245"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="41"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="220"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="329"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="372"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="396"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0016595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="865" mass="97018" checksum="DDE66BB6248BAFF8" modified="2023-09-13" version="1">MDTLPNDMFAAIYSENEVISNCSSFQQHHIPSNPFDISALTPSSSRPTLSSLDISSPDHDPFHTPSPSQLIPSPIDLANCDQDPFNRQLFSSVLSPANTLSPIKTCDAPLSESIFMQSSPKSSKFVLSLSSQRPVDRPSSPLMSNQGMNMADVNAEKTSETTLEMKGTCDKEKIVVEKKTASKMPGTAKRHSVSRQAQQHPLVTHQHHTPPPFVSPLIQRHSHHHHQHQKTGSLDLGRNGFSRFLPQQQQQQQQQQQQQQQQQQQQQQQQQQQMQFQHGHIPSVGLVTMQMPSIPPHLDSINVSTTILEEGRQQQQQQQQQQQQQQQQQQQQQQQQFHQISHQQPQPQPQSQSQPPPQPQQQQELSQIPIPSGTNAMGSTLGPQRTQSSLKRRLTKDRLSKNDREEVWPTDVEKIFYEALEVIPKLGRRKVLVDGKPCGRNELIADYIYKRTNKIRTRKQVSSHIQVLKNTRKSDAAFMKLLMDGGDGDDDLTIDIPNGYFSASESPLESPTSPSTPMNHGLLDQRRNSTTSIPSFGFQLHQQLSQLTPSHGRQHFKKHRHSQSMSSIMSETISSPFPSHLNNTHSVYQRCGTTPDSAVSLSAETSWKSGPITATSVSEDGTSETTKATIEPIASHCVTLGREDSGMGDLSTELTYPFWPSVFGLFTEYASDLTPGISHMHSLARSRDLGQQSFGSVNVHQLPQEKFPGLYDLYQKTMCTFLFFKIKLDLNLNLNGVFGNTSLFDSTERRLVECTTSIYSFGSKVLEAKELKQAGVVDSKFVYNFEFVNQFFGAFLNGIRNLTTWGEIDIALTNLSVVQVFEDKDTRFESPAPLLVMAFDFERGQGDIETFFIADGSDMLESLVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1P3</accession>
    <name>A0A9P6T1P3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007249</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000368">
        <property type="protein sequence ID" value="KAG0018370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="489"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="584"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="641"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="150"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="610"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="641"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="689"/>
            <end position="700"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0018370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1625" mass="182705" checksum="3BEAECF1BF5F72D5" modified="2023-09-13" version="1">MYWGACKRYTRKNCDYSFKGLQSTVPKALDSVPVGTIRRMGVTQAFEYINDCEAIKLADLQKEGPCEIDGTAVSYMKFKTTEGRLLLKQLKKMAKEDVSVGVPGPVLRLAHLGQESWSFPSPVATKGPTSDLFEPHLSTAPNPTLACNTSSTNPTTTQQMPSSTGLLHPASDALPPSPSHPPTDVYHELNLARDVVWPLLANVLNKLYSRVYKKSDDFIHYDGQPTTQKAFAHKRRQLATKKQHLELSKYLEVAEARLSQIEAKPKLSNRQVSRFKSFLSKHLFPCWIRARSVDPRATKAIVNELRESHGWKAHQCAGQFDICVAKKARKNPDLDLAVVSTDSDLLFVGAKRLFRLQMKGTRFYNYPIEEIINYCGLETPDEWVAAAVVSLNDYDPSVGRTSFCSAIKDVTAIREDPIFKKSKNCSVDGYVEELCKRKNVPPSVVKESLDSFVNLVETPLDRDTQGDDVIDESIRRIVYRVEALAFRSQGSQKPQSSQRPTTLTPSSSIPIQLPETEGKDNVIDMPAIQQLQLRSTTTHHVALPVARVAFPTETETVTGTIEGIEARSHANRYFPRAFTSAFTSHQKNTQSIGLKDRTVGRPGSTASVLVDEEEDDDDDDTFPDNADISNAASAEENLALEESDNNSDDNSDDNSDDNSDDNSDDDSGDNSDDNSDDDSGDGGDYEGDQQAKDQPIDAERPKKRASKKITYAKSSRKARDTNVPLNDNSVPRKINPTNLMGDAVASLHPMRAMRPGRVESCLIYSLRKSFPRMDVGDRNLLSGHILGTVQTMARVHTDLLREGLLATNLYIARTFKAFSMIDGDLGQEHSEKRMEHFNNILLKGKRDSFFQRLVSSLIKWDSSDSKSKASSPVLEAADKICKEYLRITSQRHDPPFQPKDVDVCDSSFLTQCARTLSDMVGSHIYKFSLELKRRVYLNNPSWASSDSGKAILDSIDDETGLSENHDCLSIHLILNLFLPPKAQIKILPEVGYEDSFFSFTERQLISCLLKDFRVNRMKLTPIAKRIRQLSPAEQEKQRSLARILSDVFGSKDSAVKNTQDEVGRLSLLLFLNGKNTSYRRGANLLWTKDSCNPTSSSSSSSLSLNPTSLLQQKSLETKVILKSDEMSVINEARTALEKMDAKDPQYTSSKLEFKNLIRQRLQSPEKYQEQIDNSKPRQPRQKYILTGNLSTNGYDLRVMAYKLTESRRSPAPTMEAQSKSQCINNKYSSVAPFPAGAEEQILSGELLTTSSSTSTPVPTPNTTFPWSTAPMMQGWQYVSQKFDTQEKVDGLFRNTEVQDGIRCVGIDPGIANTATAILIHSKYKNDNINLNIPRGPRDDIDQKYRKQQSRLKINAGITEIESKLVQRKPIEVKLAVGDLNATMEDDLEATCNSHDTIMPFTKAIQDYESSIEAHLINVANEASILRSFYGSTKFKKDKYDYREALRHDLDKAITAILRMRKYVPDRQPSDKDFGNILYHVKEDIATSMVFFDGLNDRKKYDWAPCQQLMSEVKEQSEKTGTKFETLLESKLYKRRWKRIAGTLYKRGFLYLNTLPHEERKTFLQSPLVIGLGDGDFRSWRGQSRGGNKFAINLIRQTQNLVKDLARNKKKEPVVIELVKIPEFRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T339</accession>
    <name>A0A9P6T339_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thioesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_002141</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000152">
        <property type="protein sequence ID" value="KAG0021566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T339"/>
    <dbReference type="OrthoDB" id="506431at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03443">
        <property type="entry name" value="PaaI_thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052061">
        <property type="entry name" value="PTE-AB_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47260">
        <property type="entry name" value="UPF0644 PROTEIN PB2B4.06"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47260:SF1">
        <property type="entry name" value="UPF0644 PROTEIN PB2B4.06"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioesterase" evidence="1">
        <location>
            <begin position="228"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0021566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="329" mass="36498" checksum="3E9D3E0764ACCA4B" modified="2023-09-13" version="1">MSLHRSTTVIQRALPRSAVAQNRGTDRAWTCPQRIQALQRYALYSTNSHNNTPPHTSTSVDTARSKQSDGRFLGWVRRLSLISVSAAAGALAYSRVEPVDMGGFSSMPRGKIQPSVLVKEEPDEFFPTGGRAAAEKTKEITRSVLLEAQMQELELVHEYKNKVKEGDWKEADPYWYLTKATEPHHLTAGSLRGENMLSVAPLKFERKDKKAIVLFMHLGRSLCGHDRIIHGGLLATVLDEATGMVALPNLPFHVGFTANLNINYRKPVKADQFVMVKAEFEKSEGRKGYTKASIHDLHGNTLTECTALFISPKNPVGMVAKYVKNSLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T376</accession>
    <name>A0A9P6T376_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_002245</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000155">
        <property type="protein sequence ID" value="KAG0021506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T376"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0021506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="117" mass="12826" checksum="848B76C831D1F4D0" modified="2023-09-13" version="1">MVRSFIFTAASPATAPFISTSHAVPVHRRDYEQTAALISDTEYCVFLPPQRGSNIADNEDRTIVFCNVLIETALNAGIISHGLIQSVHFVENTEDGWIQITGRLDPSAYDLSSDDQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3K6</accession>
    <name>A0A9P6T3K6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_000529</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000111">
        <property type="protein sequence ID" value="KAG0022330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3K6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="275"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="98"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="288"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0022330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="375" mass="43030" checksum="11EFAFC30CDA9E88" modified="2023-09-13" version="1">MPWNFRVVPDTERIEGLEKQAVKELFDKHVGTSTVTNDAFSIKASRMPFREPPPRDVPPFVQKAMLEYEYATQRYNLELVEYEQWRQGQGDAKENLESTTLSSASSSPIPKPIPPTKPLFVTQYELRNIREHPSSVDAPHPPFRVTFILSKKQISKLASHRNFLRKKLSAAVEMVFREHARKGYEFLVFAKKSAMTTPQEKLIQLMKEAVTNPWLYGERPSRQRDDKRFSNTSVRWKNNRPPVHKFWWKHAMPNPLVRVQQTDEYLDQYCPKVEAKEETPQTPTTARLSEKKKNRVEKDLHHPESDRSLIEHLITDLSHYHIALLTMSITIGSSNEKHFALARTASDLILDSTSGDSSTEAGNIGYDAGKCCVGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3U6</accession>
    <name>A0A9P6T3U6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA helicase</fullName>
            <ecNumber evidence="4">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">SWR1</name>
        <name evidence="19" type="ORF">BGZ80_010846</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Component of the SWR1 chromatin-remodeling complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF2/RAD54 helicase family. SWR1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="4"/>
    <dbReference type="EMBL" id="JAAAID010000080">
        <property type="protein sequence ID" value="KAG0022931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="372624at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000812">
        <property type="term" value="C:Swr1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd18003">
        <property type="entry name" value="DEXQc_SRCAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10810:FF:000005">
        <property type="entry name" value="Photoperiod-independent early flowering 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000655">
        <property type="entry name" value="Protein PHOTOPERIOD-INDEPENDENT EARLY FLOWERING 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.850">
        <property type="entry name" value="SWI2/SNF2 ATPases, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017956">
        <property type="entry name" value="AT_hook_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014012">
        <property type="entry name" value="HSA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050520">
        <property type="entry name" value="INO80/SWR1_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45685:SF1">
        <property type="entry name" value="HELICASE SRCAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45685">
        <property type="entry name" value="HELICASE SRCAP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07529">
        <property type="entry name" value="HSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00384">
        <property type="entry name" value="AT_hook"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00573">
        <property type="entry name" value="HSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51204">
        <property type="entry name" value="HSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0010">Activator</keyword>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="14" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HSA" evidence="18">
        <location>
            <begin position="732"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="16">
        <location>
            <begin position="1310"/>
            <end position="1475"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="17">
        <location>
            <begin position="1853"/>
            <end position="2003"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="524"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="862"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="920"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="964"/>
            <end position="1031"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1045"/>
            <end position="1157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="2080"/>
            <end position="2126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="2174"/>
            <end position="2262"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="2044"/>
            <end position="2071"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="19"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="43"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="64"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
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            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
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            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
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            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="225"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
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            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="312"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="341"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="393"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="424"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="453"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="524"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="863"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="971"/>
            <end position="985"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="986"/>
            <end position="1013"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="1137"/>
            <end position="1157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="2081"/>
            <end position="2091"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="2178"/>
            <end position="2198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="2199"/>
            <end position="2210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="2211"/>
            <end position="2236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="2247"/>
            <end position="2262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAG0022931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="2262" mass="251867" checksum="D2FF9EA8664CD9BF" modified="2023-09-13" version="1">MSQPSESNRFALPPAVAATSETGSDATDSLHSSPATPKLGVVSSSNLSHQSDHSSSSSDPLVLNANNSSMLMESDQATSLSNGSSLSSRSSSSCSSSSSNGGEGSGNNSDVAGNSASVLQATTSISNVTQSSPMSTTVFLKEVSEQQSSPQNLSAGAPEDSNSTCQPCYTNGHASHEAALSSDASVVSDNPPKRGPGRPPRSQTSTTVPAEKPIDLNRPRRTLRAVTNSSSINTSVTTTASTTRLQETPGKGNQPVITSSATSDLIGPARPVGQRSSTRNIRPPGKFIESSSLVGPGRVSSTKATPSNQRPLIIQQQQQQQQQLQQASDQFRKRGPGRPVSNPSAHQSRNGTSSKVMPSPPPPIIPLKRGPGRPPRNPLSPKATPHVVASAPTPRTKSKSASPTMLRTSNQSSSNATRSNSAVSTPRSTSSTGSEPSSATKRGPGRPPRNLDANSLSASASSTSPSWKHSDQMQVTVQGSRSRKRHNKTEAEAEEEEGSSTVYGYNEEFGLTPRKRRVMSLNQSILPSQGQNTVKSRSSVPEPARPSKPLTPLDKARQAKITEWEGKLHEIIDHHDSLARELYHLETYTTTLTYDPVKIKSDHSERMLRFLRNFDLWSQVPDLVSNVQLNTDRISTRRSAIEQREQLVDMLQKNVEVALPRRGDGGDMIRLGSHRGYHPQFESLEDYLNSFVYVDDEEVTPEESDARAKSHAELLDRIDALKAEGRLGGKPPKAFVDPEVPKLQYNWLMEHVMTSSRLIKEEGKLQMARARKVSKMITRHFEQLNGKSEREQRLEEKRIRKVAKLTANEVKKKWRYVEGIVKARHKALLREEQEEAGKRHLNLILEHSTQILEVQQSTLIVNTPGTPGTPQGPISDSALSDILSDRPSTPSITEMPSPRSSVALSVVSSEAELDAGDAEFTAAEPDADDETTLANEESGTEDDEEEISGLAAEMDIPIEELLKQYGYQLSGDEDSENDDVDEDGDQDRSMEEPSINEEKPRVSSRRAQKEVAKSETAQEPAVKPEVGAETGLASVLKDVLLDESMDMEIDSTSEAGKAGESGIKELDELPSAPPSPKQSDEEKALSSKEIANALPESLKSTSTPALVQERGHYTKRRRLSLTGLYRGPPLPWNPYGEVDDERTMEQEEQEEQSDPEEIADLMQEKDMSIEELLDRYAYEAESSEYSDSYYDSDSEYEGSIMSSQQRVRQADPRFVVTLQDVVASRKFPTRPSSEFTDTDTEYDDNKTISIYGSDDELCLGDMLPLLDPVIPPKSPEVETFTTGANVKTKIPFLLRHQLREYQHVGMDWLASLYSNGLNGILADEMGLGKTMQTIALLAHLACEHGVWGPHLIVVPTSVMLNWEMEFKKWCPGFKIMTYYGSPRERKEKRVGWSRDNSFHVCITSYQLVVQDQSVFRRKAWQYLILDEAHNIKNFRSQRWQTLLNFNSTRRLLLTGTPLQNNLMELWSLLYFLMPNGVSQTMPVGFANQKEFQEWFSHPVDRMIEGNEQQDEDSKAAIARLHTVLRPYLLRRLKADVETQMPAKYEHIVYCRLSKRQRFLYDDFMSRAKTRETLASGNFLSIINCLMQLRKVCNHPDLFEVRPIVTSFAMPSATSSFEITEFLVRRKMFSEIDKARESVNLEFLGLIFTNAEERLSKMDLETYQELDVSPIIQKKTAEFSTPQSKTLTGGNHYQDIRQYASVRRHRQMQATRNRWEQMNYVNSNRCRAQLVFGSSLLDMVRAPVKDARGCANILDQVADPRQYFNYTDAIANLVIPSELRFHRDEETIKRFAFVTPAVLVKDYTWSPIHVNPSPSNMEVVCQKATEFLHPLSSCLQIQFPDKRLLQFDCGKLQKLDSLLRELKSGGHRALIFTQMTKVLDILEIFLNIHGHRYLRLDGATKVENRQHLTDRFNSDPKILAFILSTRSGGVGINLTGADTVIFYDSDWNPSMDRQCQDRCHRIGQTRDVHIYRFVSEFTIEENMLKKANQKRMLDNVVIQEGEFTTDYFQKMDWRDMLGEEDLAKIGDLGPIQSDGGSQGITTVQGADLEQALAAAEDENDVLAMQQAKHEMEDVDLGDFSEVRTNTAPGTPQSSIAAKGSGKKSKMSETGTGGAKVQFATSVEDAGDDDEDYEVIEMGHVDEYMLRFMEREYGHYVGFGGLPKPVKNETLENLEMLSNADEEEEEEEEDDEYDVEESDGSDSGNDNAGDSAPSDEEQEGENDEDGDGDGDDGDDETDVTGGQARGNDEDGEETEDVQPMEEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MCL6</accession>
    <name>A0A9P6MCL6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_008831</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004928">
        <property type="protein sequence ID" value="KAF9991893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MCL6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9991893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="172" mass="18595" checksum="0FE82DA6744E5242" modified="2023-09-13" version="1" fragment="single">RSITTPPHTLKLSVMLVLRSAVTIVAVALLSFGAIVDARPVEYATDPAPQYRIDTTKLPGLDSGLTALPQWSGNMPVGSGNTLFFWYAQAANPTSNNLIFWHNGGPGCSSMEGLFDENGPYHSTDGGKTWTLNPHSWHNNGHIVYIDQPFGTGFSTDKTSVPNEDFIGDTMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MCU8</accession>
    <name>A0A9P6MCU8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008659</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004772">
        <property type="protein sequence ID" value="KAF9992202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MCU8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9992202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="83" mass="8471" checksum="82AABFC6E7FD7A2D" modified="2023-09-13" version="1" fragment="single">MPATPSKAKAATATTSAAATSVEGKTTETVTGTSTTVVTTVEETVATLEVTNESSVLEVSEVDITTSVTVSARELPIFKNPLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MCX4</accession>
    <name>A0A9P6MCX4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AMP-dependent synthetase/ligase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004463">
        <property type="protein sequence ID" value="KAF9993020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MCX4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043041">
        <property type="term" value="P:amino acid activation for nonribosomal peptide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.980">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.38.10">
        <property type="entry name" value="Luciferase, Domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020459">
        <property type="entry name" value="AMP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF1">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00154">
        <property type="entry name" value="AMPBINDING"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="1">
        <location>
            <begin position="34"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9993020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="247" mass="27214" checksum="47F356AE2779E927" modified="2023-09-13" version="1" fragment="single">AAKLLITNEERHIPDQIQTPLLRISDNYEDTEGLQGPVAFSKPLQSATSSLDTAYIMYTSGSTGRPKGVMVSHRGIARFVINNGFAPMDSDDRVAFVSNPAFDHNTFDVWTPLLNGARVVIIDNDTYLDPYRLAAALDHHQITALLFTTALFHQYASIIGPSLSKLKYLACAGEQGLIEAFAEMQRHGGNVRLVNAYGPTEVTVHSTTYEFTSDSSQLDRLPIGRPISNTRTYVLDKYRNPVPVGVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MDA5</accession>
    <name>A0A9P6MDA5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008092</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004297">
        <property type="protein sequence ID" value="KAF9993551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MDA5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9993551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="172" mass="19727" checksum="C5CE8530F1975A4D" modified="2023-09-13" version="1" fragment="single">LQSLQTLYRQKTDQLHHSAASNSETWTRRHREKMTFNKYRTVEREDQQQRYAIRHHPTKNGYLQDEPTIAKKHQWKPFKAKDENDEGKEAQPSKKAPSMPRTVSSPDPQNKAKLVDAMRKQHPIATLNVGALKANINRIVEVPGSAPQAVRDEALSVIQSAVQFANDIKRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MDC5</accession>
    <name>A0A9P6MDC5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_008119</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004309">
        <property type="protein sequence ID" value="KAF9993503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MDC5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9993503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="102" mass="11696" checksum="52393EFB063FB543" modified="2023-09-13" version="1" fragment="single">NGKPHAKKPTPVPWICPAMEGHCEGLSSRGSTQSLLLDEGTFDRSPDLQKPMAALYRGTTPRCLIAEWSEYFQSLRTIARHIIHKFVEYLESQATERIWKQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MDT7</accession>
    <name>A0A9P6MDT7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004331">
        <property type="protein sequence ID" value="KAF9993440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MDT7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9993440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="226" mass="25605" checksum="B3AFD128A3E238AF" modified="2023-09-13" version="1" fragment="single">SALTALGIVSRNDYGKGIHNLGVKTNIKVIRLVDNKEPSTAAKVRKLICAYLEHTTVSKKQLAMGVEWSIESYADAYDVFVNMRQQAAETTNSATPSFSDLQLRKIKVQRLYAERRHAEYKARKARRAAQSSDVSQSKPTNPFLAIDKPNSTQLQTHRPRYTPKVRYEPIEKQAPPQIYLQHSLKAWKQPPEREETTLKDPAPKKPPAPIRPKLEEGVLPGRKDIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ME91</accession>
    <name>A0A9P6ME91_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_007752</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004019">
        <property type="protein sequence ID" value="KAF9994650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ME91"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9994650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="203" mass="22382" checksum="9165821A02715E73" modified="2023-09-13" version="1" fragment="single">MVLFSSSPSEIPPGDMLEIANEHLKNAQSAGTPTRAILLCRSAEVLIMDAEDVVANKRVGGQALTNNIISAYQRHGKLLEELGQQSKAQKSYRSAEKWGRFYVTGQHTRIPQSNSKASIPSLGQQVIFTKDITPPIAKFTLPEIGGRVTSTNQLAYCISLLYSSLASNEEISKTEYNWTQAMINNPDEQARLHTMATDVIRAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MFU7</accession>
    <name>A0A9P6MFU7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006932</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003462">
        <property type="protein sequence ID" value="KAF9997757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MFU7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9997757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="82" mass="8833" checksum="85D287DDACE68C56" modified="2023-09-13" version="1" fragment="single">MSLPRELGFQGTDRKCDDVQLSLTPSAIFASKIIIRTIAVLVTALGQVHLDYDISTDVSANQRNKSNGSDNPVACQPGVCRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MIE9</accession>
    <name>A0A9P6MIE9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Translocation protein S66</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">SEC66_2</name>
        <name evidence="3" type="ORF">BGZ80_005896</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002901">
        <property type="protein sequence ID" value="KAG0002908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MIE9"/>
    <dbReference type="OrthoDB" id="73168at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031207">
        <property type="term" value="C:Sec62/Sec63 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031204">
        <property type="term" value="P:post-translational protein targeting to membrane, translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018624">
        <property type="entry name" value="Sec66"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28229">
        <property type="entry name" value="TRANSLOCATION PROTEIN SEC66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28229:SF1">
        <property type="entry name" value="TRANSLOCATION PROTEIN SEC66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09802">
        <property type="entry name" value="Sec66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0002908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="198" mass="22791" checksum="1BE987C67F67DF5E" modified="2023-09-13" version="1">MGSVWLAVIYIGGWILSMRIFGYFWKNRKLAINDAEPWFGEHVARNQYIALLQQEEPEASENQLTAALLRRAMEDVIRVLSMREDKQVLANLVKQGTVGDDIWTQFSLSEKELEAEIMAVIEEANTFKEGWGQTILQTASEMVAHEKTKQLQKELALRREEEARKQALREQQKEKASKSKNEKLESKETEPEPEKVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MJ65</accession>
    <name>A0A9P6MJ65_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005619</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002769">
        <property type="protein sequence ID" value="KAG0004418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MJ65"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0004418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="166" mass="18935" checksum="8A91CF3E0721F7E3" modified="2023-09-13" version="1" fragment="single">DARDAYHEMRDVRFEGYRLDVQYAKNAPSASWRYERGGGRGRSRSPPRRGRSPPRRRSPRRSPSPPRRRSLSPRGRSPSPRGRRPRSPSPAAARRRSSASRSPVRGRSEERRDRDGDQAMSPRRSRTPERRPSDAGNGHDRGEGGRSRSPSPRRRSISPRPRSVTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ML42</accession>
    <name>A0A9P6ML42_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Golgi apyrase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">YND1</name>
        <name evidence="7" type="ORF">BGZ80_005079</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the GDA1/CD39 NTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002522">
        <property type="protein sequence ID" value="KAG0006971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ML42"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004382">
        <property type="term" value="F:GDP phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017111">
        <property type="term" value="F:ribonucleoside triphosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045134">
        <property type="term" value="F:UDP phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046036">
        <property type="term" value="P:CTP metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006256">
        <property type="term" value="P:UDP catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.150">
        <property type="entry name" value="Exopolyphosphatase. Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000407">
        <property type="entry name" value="GDA1_CD39_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11782">
        <property type="entry name" value="ADENOSINE/GUANOSINE DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11782:SF121">
        <property type="entry name" value="NUCLEOSIDE-DIPHOSPHATASE MIG-23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01150">
        <property type="entry name" value="GDA1_CD39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01238">
        <property type="entry name" value="GDA1_CD39_NTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="186"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="444"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="676"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="784"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="872"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="917"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1039"/>
            <end position="1151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="207"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="444"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="472"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="696"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="784"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="811"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="872"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="917"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="974"/>
            <end position="1000"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1001"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1050"/>
            <end position="1060"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1075"/>
            <end position="1086"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1105"/>
            <end position="1116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1126"/>
            <end position="1151"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="162"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="234"/>
            <end position="238"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR600407-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR600407-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0006971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1151" mass="122975" checksum="AF55C9543234EA42" modified="2023-09-13" version="1">MSSLHSEKWLQNRQFGIVIDAGSSGSRIHIYSWINRQHLNNTAPAREFIGVLPTIEPGVESGSPNSSDWTLKTEPGIADFKERPEDVGEHLEPLLDHAQRVIPESEVPNTPIYLLATAGLRLVQDDIREKILANSCKYIKENYQFMIGDCEKHIKNITGEEEGIYGWVAINYLMGGFDDGGVKMIDSELPGSEQHNTDDWEPVPPVDPHDSNTDASKDNATPHRHTLGFLDMGGASTQIAFEPSPKASEDHANDLTNVILNTLDGQKLEYHVFVTTFLGYGSNQARRRYVKDYLLSNNKDLLETQKPGVQISIMDPCLPKHLQLNETHTLPHVPLTGSGSFAECLKRVEVLLNKDKECSDVPCLFNGVHTPPIDFNINTFIGVSEYGEKGAIGSEEQSNEVLEKAEESIKNKNWRPPFQSINAIKDIQVTWTLGAMLLISSGSMGPSDSTDSTGAHGHDGERHRPSQILPPADHEAPHEDSYPERMLDSYNHFMLLAIALLALAIFWVYKSRSSRSWPILKKFLLPTSSSSPGGSNNNNGGGGGGFPLFGRFRRAGGISGADYSALESGTVGGPGGSFGRGFSPRASLSVAYFNVVHRTRTALRSLVSRVWPEPANFNSLNEGQEGLVGISIGGYDGNSNGAAALPMSAVSGGVGLGVHVPGGNFAASGLSAIPETGGGHPTGVFDPGFHRSHSNPPAAGSSGGSSRPPRTIPSFLRTKKRMSGDSQSIFGNKDKRGHHGTGAGGCVVSTALPQKQDQNFVELTARSGSTTNLLNMWSSNNNSSNNVGSLSPNINSNSPIHNNNNNNSNSTLQVPGTGSVDQSGWKQGWIPEEEYEDPPIPSLLTTSRSYNTVSHSSGASPLLTPMARYKQQQLVHQDGSTSAPSSTLNLASAMSGNGNGGGGFASGFVTSADERDEWSADNDDGYEDGDEGDGYQESSFYHQHRHQSHPYSRISGGGNNNNSNTVIHQYSQNPVRSSSAIPFSSSKPSTGTFSSSPTPKLTHSQSNQAVPSRSQTPQNQYKQRSTGILSGINFGNGGGAMTTLDDNESASEGGYLSGSSSAGGGGSNGRHNNRPAGSSIHTTTGLLQGGAKIGGSRSVSPMMFNQQQNNSTSTSSLVLGRHNVSEQDQQLVSRGSSENVRRSSTGTIVSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MLF4</accession>
    <name>A0A9P6MLF4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ubiquitin fusion degradation protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">UFD4_1</name>
        <name evidence="5" type="ORF">BGZ80_005207</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002581">
        <property type="protein sequence ID" value="KAG0006623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MLF4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016607">
        <property type="term" value="C:nuclear speck"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2160.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045322">
        <property type="entry name" value="HECTD1/TRIP12-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45670:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE HECTD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45670">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE TRIP12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 3" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="HECT" evidence="4">
        <location>
            <begin position="1"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="3">
        <location>
            <position position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0006623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="202" mass="22724" checksum="3F6B78B3F7EAB956" modified="2023-09-13" version="1">MSLDFTLAGYPEIELKRGGANIPVTIYNVEEYINLTLDFTVGQGIQAQVSSFREGFNSVFSIQNLAGFRSGELVGLFGSGEEDWSYETLVDSVKADHGFRSESRAFKNLLRVMSELNKEERRQFLQFITGSPKLPIGGFKNLHPPFTVVCKPFEAPLKADDYLPSVMTCANYLKMPDYSCKEVTLRKFKMAYEEGQGSFHLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MM71</accession>
    <name>A0A9P6MM71_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_004815</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002410">
        <property type="protein sequence ID" value="KAG0007321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MM71"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="143"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="530"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="631"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0007321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="768" mass="87494" checksum="114CFFA52EDBB8DB" modified="2023-09-13" version="1">MDMESSDGEITQVDILQHSVEIVKQEGGKGSHRFSLSFRWTSNYRGVLYVRIYVGGATNYSSDIRKEMTKAIQDIASRPEDTAGQRKLITDFQEIYKLYNVIHHLALNSVVYLDKSRILSALNIEQLTPIDPDGRFDKLEEVSLDTTDPSQKDISPDNASHETTVDQGDRAETTHSVISKFGQRLLDRRIETWTKVEYNDSMSRDTARIHAIPDTDATSLLTNELVYNILVLGETQSGKSTLIEGIKRYADPTYKIDEGAIGDGNFSHTAKVRTSVVTTNMPPYYVFETSETIEGKVQKSQIDYGRFIEMDKDDYEDAINQRRGYELTKGTSDQSERIFKLIDTPGLNDTNNFDEIHIGSIFKALEGIQDLHLVLITVPDVTLSDGVKDAIKCYVDMLPTFKGILAFVHTRIRHKRLHPEDTRFAESMNQKKKALENIIKAENVPHFMIDCNLKSVKPIQLCIAQNTIRSILSLATFNQSVRVTAMTMVKTAKMVHVDKFLEERYKSLIEARKRAFAHMDLDRSEVLGAIGELMASIGEKEQELQHVQRELSLHRSDELVLFSQQRFDQDWSPLTTIATERMTLDSTPYLIDHIDVLRHNVSIIEEKGGKGSYYWEAKFRMMKFQHGVLHAKLYIKKRNKYQEEIRRWEAAVSRLRGEIEDLRNNLLGYKVWNQELQGDIEALLSQLGLDQYLLSQVSENELDVGVFYELVNSGAYVGSMPENLEAVEKFFLENRARLENQANAALQVVGDPVDTSTTFIDTGMALDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMD7</accession>
    <name>A0A9P6MMD7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Zip zinc transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_004188</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002160">
        <property type="protein sequence ID" value="KAG0007825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMD7"/>
    <dbReference type="OrthoDB" id="200954at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005385">
        <property type="term" value="F:zinc ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006882">
        <property type="term" value="P:intracellular zinc ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16950">
        <property type="entry name" value="ZINC TRANSPORTER SLC39A7 HISTIDINE-RICH MEMBRANE PROTEIN KE4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16950:SF16">
        <property type="entry name" value="ZINC TRANSPORTER ZIP13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040446129" description="Zip zinc transporter" evidence="7">
        <location>
            <begin position="29"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="111"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="144"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="182"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="344"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="400"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="435"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="210"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="217"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="235"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="245"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0007825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="456" mass="49190" checksum="5A9FB749DDA3A0E1" modified="2023-09-13" version="1">MATLNRSRAVKLLAFAALVLTVVTLVQAHKGYVQNGMPNDRVHANVDPNKAGECPFHAAKAAQESEQEFHALPIYDKDGNLVGSGVSHDNGEITSSRMKALFAFLFPGSPMVNSLLGTTYISLIPNLLLYFVPPDIKPESLNTLVAFAVGGLLGDVFLHLLPHSFLGEVQTGDLVTANEKKNVIVGLGIFVGFFVFFCIDKVMRVLSGGDGGHSHSHGHDHCKKIDGDNESDHHHHDHDHKHDHKHEEKDSTLRQRKGGKDQDAVTKDEPAKKEISNSIKLSAYLNLIADATHNFTDGLAMAASFYTSPAIGATTTVAVFFHEIPHEVGDYAILIQSGFPRSKAMMSQFITAIGAFLGTLAGIAIEEMSKVTEDGFEKGVKEQKLALFGIESIPMRAGDLVIPFTAGGFLYIATVGVIPELLTVSGKLAKDARQFATEIVAMLIGVGMMTIIALNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMP6</accession>
    <name>A0A9P6MMP6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="6">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">USP14</name>
        <name evidence="9" type="ORF">BGZ80_004977</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="6"/>
    <dbReference type="EMBL" id="JAAAID010002484">
        <property type="protein sequence ID" value="KAG0007180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMP6"/>
    <dbReference type="OrthoDB" id="333239at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070628">
        <property type="term" value="F:proteasome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061136">
        <property type="term" value="P:regulation of proteasomal protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02657">
        <property type="entry name" value="Peptidase_C19A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16104">
        <property type="entry name" value="Ubl_USP14_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000119">
        <property type="entry name" value="Ubiquitin carboxyl-terminal hydrolase 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044635">
        <property type="entry name" value="UBP14-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43982">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43982:SF1">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="3 6" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="7">
        <location>
            <begin position="7"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="USP" evidence="8">
        <location>
            <begin position="109"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0007180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="496" mass="55655" checksum="898925D9692B0CD5" modified="2023-09-13" version="1">MPPANTIKVNVKWSGKKFDDVELNLDEPGLVFKAQLFALTGVEPDRQKIIVKGGMLKDETDMNKLGLKNGHTFMMMGTAGELPKAPEQKIVFAEDMTEATLNKAMDVPIGLTNLGNTCYMNATLQCLRVAPELIQDLQKYPGGTDNLDSGSNMTASLRDLYRQLNASGHPVMPIGFLTYLRKAFPQFSQQGRDGTWMQQDAEECWSQLISTLKSKLPPYAEGKQNVIAQFMQGEFTTTLKCDEAPEEEAIISKEPFSKLDCHISSNVNYLHNGILESLDQKIEKNSPTLNRSAVYSKSQRISRLPAYLTVNFVRFFWKPTEQVKAKILRKVKFPFELDASQFCTAELQEKLTNTKVKLRELDNAETSLKRRKRLDKEAGRMETDEVSEEQKAVDAAYVALEGSLDPELVQDVGSNPSGQYELAAVLTHIGRTADSGHYIGWTKKGDTDEWYKYDDDKVSPVSKDDILKLDGGGDFHVAYMALYRARSFKPKKTTEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MN73</accession>
    <name>A0A9P6MN73_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_004309</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002209">
        <property type="protein sequence ID" value="KAG0007730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MN73"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="98"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="291"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="105"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="165"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="211"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="224"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0007730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="323" mass="35353" checksum="D7A6446664A7660C" modified="2023-09-13" version="1" fragment="single">MSNQDFLNLPNSPPPALAGDPSMQLFNSSEQRYFSEFLDTLVVDQDFTFDPSSIPNLPNLPLFTSETMPGGFSLDSPFMFPSSSSSFNSNPTMINSNAMDFDMTSPSSQSSFSGSHSFPNHFSHGSDSPTSPDSPSSSHYYTHSSNASAPNKQRANKSAEARRTSSISQDSSKISTLQQLSKLSLDGNSNGSSNRPSNPKKNKRDEEEHPSVSSPSASISPPSRSREQKEDKLERHASVSDGSISDAANGVVGTSATTKRKPYKELLTEEEKRANHIASKSTILFKAVDFIKHLERQNRMLQEKANKLESRLMNQRDDSNVSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MP25</accession>
    <name>A0A9P6MP25_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_002794</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DONSON family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001704">
        <property type="protein sequence ID" value="KAG0009050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MP25"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033260">
        <property type="term" value="P:nuclear DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024861">
        <property type="entry name" value="Donson"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12972">
        <property type="entry name" value="DOWNSTREAM NEIGHBOR OF SON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12972:SF0">
        <property type="entry name" value="PROTEIN DOWNSTREAM NEIGHBOR OF SON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0009050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="232" mass="26341" checksum="6226C295530AC6C5" modified="2023-09-13" version="1">MSSEIEATLTNSTPGLREVLEREEIKFERLPNTARKTTIHNFSSKHDLENFDEDDMESISKSTESKALLLQPENHNLSDNLLFKGSLDVHGLFSYLLNLKPSYEDGFLHQSPNLIARVPFHHAALKRAQISKCRVVSRHTEGTDKMQTEFRVDVQGTLLPTSVNEFHRVFAGQQRATGYTCVASSEPRSLGLNLRPLLNDQTKSPEIPPFVSPKALDQLRYNHSLKQFSWLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MP56</accession>
    <name>A0A9P6MP56_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_002719</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001683">
        <property type="protein sequence ID" value="KAG0009120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MP56"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="224"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="255"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="407"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="79"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="190"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="407"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="419"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="442"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0009120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="478" mass="50154" checksum="ED485C950C91B4FF" modified="2023-09-13" version="1">MEGQKYDIKEQHQKLYRDDHDGSKHYTPNRHPHGWRQYRRTSKDSSNYNDPERFSEFLIDNKKRDVISNIIQDEVPLVTTGDTGTSSPSPSFTATTTDTSSEATGTTTLTDTDTATPSTTTVPTTIDTTATTTTTTTTTTTASTNPSSVLVTSNPVTTTPPVTSQPSRSSSSVNPTKTEPSTSKNSGKHSQTAPSTSSSASADGSVSKSPNTGSSDSSLSNKTAITIGVAVGAVVIAGSIAVWIFRKAKLSPSRQFKSKIRSSELGGSSGSRDFEIDTRDQDNYADIFRPLNHTTERPLTTNSIGGTGVGAAPSVTGSSPQSQHRDYQYQDYQDYQQPQHMITSSQTVPDYSQYRYAQGGHGPVMSGAGGGYESGVNEAIIGGASSSGLSNTYNSTMGGAKETVGNTIGSQNLESSGRAQKANAQAAQTTQDAQTHAKGVGNTIQGAAQKTAGSATNDTSLESRGHANAAVGDAQRSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPP9</accession>
    <name>A0A9P6MPP9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Low-affinity phosphate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">PHO91_1</name>
        <name evidence="9" type="ORF">BGZ80_002229</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001545">
        <property type="protein sequence ID" value="KAG0009601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPP9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006797">
        <property type="term" value="P:polyphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01115">
        <property type="entry name" value="SLC13_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004680">
        <property type="entry name" value="Cit_transptr-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10283:SF92">
        <property type="entry name" value="LOW-AFFINITY PHOSPHATE TRANSPORTER PHO91"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10283">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 13 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03600">
        <property type="entry name" value="CitMHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03105">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="405"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="436"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="486"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="533"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="612"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="658"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="684"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="712"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="752"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="797"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="840"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="domain" description="SPX" evidence="8">
        <location>
            <begin position="1"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="40"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="124"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="142"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0009601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="868" mass="95597" checksum="6670721D6C80DD08" modified="2023-09-13" version="1">MDFVTASLCTIFDEVGNRYSNLKKIIYQIEKDLVAAGPDIESGLPTQNQEPNETTQLLSPGTQATARAHANSTFLPALDKELDKISTFYYKKERELYAEVEAIVSDVQYIESVEHTFPVRVEAGAGGHSRRSSVGTGSIKWAKSRRNSRASRRSISGRTGSWSYDHESILANLAEAQNATAAASQDPDGSTSEYAILRGHRTASPSEITPVSHTDMPHDRVDIENHEEGRDEEDDDGIRSLWSEPEMEENRIQFRHRIIEMFVNLSELQSYAKLNCTGFSKILKKYDKITNNNTKGVYMNQVVLQAYPFKQETTAKLQEQIDRVISIYAKIFVDGDIGATKQTLRMHLREHMVWERNTIWKDMIGLERKSQSVAVSQPLDVERTPVYIKTPLGSIKLPMLLTRDALVMALCCIVFIALLSIDLFEMPEQQNCFAILVFASILWATEAMPLFVTSLLVPLLVVMLRVMRGDDSDHSRLGSQAAAKKIFSLMFSPVIMLLLGGFAIAAAMSKFHIAKAMATVVLSRAGTHPNVMLIANMLVATFASMWISNVAAPVLCFSLIQPILRTLPPGSSFGKCLILGIALASNVGGMASPISSPQNIIAIEYMSPAPSWFEWFVVALPVSLVCDLVIAALLLWTYQPSINTPTLSTIRSTKDPITKTQVFVCGVTAITIILWCFEHRLEWLFGDTGLIAIIPLLAFFGTGVLTKEDFNNFLWTVVILAMGGIALGKAVESSGLLHMITVQVQEYVQDMTVFQVSCVFASLVLVVTTFISHTVGALIILPIVAEVGASLPEPHSRLLVMSSALMCSGAMGLPVSGFPNMTAIMMEDEMGLRYLNTIDFLKVGIPSSVLAFMTITTLGYGLMGMLGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQ63</accession>
    <name>A0A9P6MQ63_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Multiprotein-bridging factor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">MBF1_1</name>
        <name evidence="7" type="ORF">BGZ80_001908</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Transcriptional coactivator that stimulates GCN4-dependent transcriptional activity by bridging the DNA-binding region of GCN4 and TBP (SPT15), thereby recruiting TBP to GCN4-bound promoters. Involved in induction of the ribosome quality control (RQC) pathway; a pathway that degrades nascent peptide chains during problematic translation. Required to prevent stalled ribosomes from frameshifting.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the MBF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001452">
        <property type="protein sequence ID" value="KAG0009952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQ63"/>
    <dbReference type="OrthoDB" id="10253401at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="entry name" value="lambda repressor-like DNA-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013729">
        <property type="entry name" value="MBF1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10245:SF15">
        <property type="entry name" value="ENDOTHELIAL DIFFERENTIATION-RELATED FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10245">
        <property type="entry name" value="ENDOTHELIAL DIFFERENTIATION-RELATED FACTOR 1 MULTIPROTEIN BRIDGING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08523">
        <property type="entry name" value="MBF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="lambda repressor-like DNA-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="6">
        <location>
            <begin position="82"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0009952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="148" mass="16090" checksum="7AA732F7DCC8A514" modified="2023-09-13" version="1">MSGNVGWDDEIVLRKRSDHAKVTRSESDINAARRSGAVVATERKVVTNAGHVGEDFRRIAKLAETDEIIAPKAISMDVGKAIAQARITLKLTQKELGVKVNEKQTVINDYEAGRAVPNQQILGKMERALGVKLRGKDIGSPLTFGKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQG9</accession>
    <name>A0A9P6MQG9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_001848</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the argonaute family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001432">
        <property type="protein sequence ID" value="KAG0010032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQG9"/>
    <dbReference type="OrthoDB" id="10252740at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02846">
        <property type="entry name" value="PAZ_argonaute_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04657">
        <property type="entry name" value="Piwi_ago-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.260.10">
        <property type="entry name" value="paz domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014811">
        <property type="entry name" value="ArgoL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032472">
        <property type="entry name" value="ArgoL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032473">
        <property type="entry name" value="Argonaute_Mid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032474">
        <property type="entry name" value="Argonaute_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003100">
        <property type="entry name" value="PAZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036085">
        <property type="entry name" value="PAZ_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003165">
        <property type="entry name" value="Piwi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045246">
        <property type="entry name" value="Piwi_ago-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22891">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08699">
        <property type="entry name" value="ArgoL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16488">
        <property type="entry name" value="ArgoL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16487">
        <property type="entry name" value="ArgoMid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16486">
        <property type="entry name" value="ArgoN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02170">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02171">
        <property type="entry name" value="Piwi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01163">
        <property type="entry name" value="DUF1785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00949">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00950">
        <property type="entry name" value="Piwi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101690">
        <property type="entry name" value="PAZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50821">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50822">
        <property type="entry name" value="PIWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAZ" evidence="3">
        <location>
            <begin position="292"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="Piwi" evidence="4">
        <location>
            <begin position="558"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="30"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU361178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0010032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="896" mass="99279" checksum="0643121290646741" modified="2023-09-13" version="1">MPKVNSTPRTEVTTGPIPHHRPDPSSSRSENTSSHASFGSTPSSALAPPIPSNSTPITVAGALTGNALKPDNGGTIGRPTQVTANFFPLKTLPTSKIFHYDVGITPEIPPQKARTIWGTLSKEADFANDHSRTVFDGRCNAFSISELISISEARTFKIDLMDGRGARPGANVFTVKIAFVAVIDVHELQLFLDRRGPFTSNCATAIQALNIAATHKSFSNMANLGRSVYSPSGAVDLGGGIEKWDGVFQSIRPGQRECFINIDTTATAFVNSGNAAEVIFRTLGTEKRQPCGSYEILKLERTLKGCVFTIDRGSSQKRYKITRLSEKGADRTMFDLVNNEGRTSTVSVEEYFAQQYDRRLRYPSLPCLGAKGSKTTIYFPAELCFIVPGQHHKKKLNEDQVAKMITCTAIKPHLREEKIRKSLRLLDFDNNTYLKAFGIQISSQMAIVPARVLSAPSIEFYDGRERPNMGSWQVRGRHLKGARLKSWAILCFEREDRSPRAVIMNFTRRLAGILSNAGMVVGSSQPPIIYAQPHGDIGREIESVKRLAEREFRRPLQLLMVLFPNKSAMYPVVKTYCETSRSGLMTQCATTKNVSRCNDQYCRMISLKINTKLGGIVSTLGSSSIPFISRMSTLVIGADVSHPSAGEDRGKPSIASVVASIDDMAAKFVGRVIVQDSRMEVIRNLQSLIKEIIKTYKHVTGHHPKRILFYRDGVSEGQFESILNTEVKSIKQACMEFGNDYMPPLTFVIVKKRHHARFFPGRGESDRSGNCVPGTVVDTVITHPTEFAFYLQSHSGIQGTSRSTLYHVLLDENKFTSDSLQQLTFNLCHVYCRCPRSLSIVPAVQYAHLLAYRGRYYLDNGAVPVDNGQGQCVEPNPTPFGEIKVSEKIMNQMFFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQJ9</accession>
    <name>A0A9P6MQJ9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RNase III domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_001788</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001416">
        <property type="protein sequence ID" value="KAG0010100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQJ9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004525">
        <property type="term" value="F:ribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00593">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.380">
        <property type="entry name" value="Dicer dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1520.10">
        <property type="entry name" value="Ribonuclease III domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038248">
        <property type="entry name" value="Dicer_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005034">
        <property type="entry name" value="Dicer_dimerisation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000999">
        <property type="entry name" value="RNase_III_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036389">
        <property type="entry name" value="RNase_III_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14950">
        <property type="entry name" value="DICER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03368">
        <property type="entry name" value="Dicer_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00636">
        <property type="entry name" value="Ribonuclease_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00535">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69065">
        <property type="entry name" value="RNase III domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50142">
        <property type="entry name" value="RNASE_3_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase III" evidence="5">
        <location>
            <begin position="156"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="RNase III" evidence="5">
        <location>
            <begin position="327"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0010100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="483" mass="55018" checksum="7399E1A61F29F381" modified="2023-09-13" version="1">MSTVTTRSSRIYLKAKIDHPVVTFWKTAAPRRTFGMIQGRIVHRGEVMDSQPFRITNGQTKESQALLEYCKVLGQRKPVYSYFKRRRYDCTLTMPYNSHCPILRSSLYHSKRLAFEAVSREACNVLVGKGILDEHSLTPLRASPRTPTRQEFGNRTISAHEQIQLGLESIPLDLLREALTAPSEGEEDDVGHNWCDLGKSFIKFYLATYFFARCQYEAEGPLTTRIHNETCPGSMSQYMLISGLVPYVRAGQNMIYTENTARMVFRKVVGVAIQCGGADNGIRVLKNIGFVLDQSVTTVRDIQSVYQRYYPPHSIRPYAPVKDNSVESQVQNALTYQFRDPNILRMTIRYHKGRDPHAYQRLELLGDAILDFIINDHYHDRSSEFDLGKYKQFKNRTISNFALGSLLISLGINTMFAKMRKQIPDTGKLEIKKSLGDAMEALIGAVFVDAGFDLRATHEMLSRTLIPFVEKGEVGPSYEHMKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRF9</accession>
    <name>A0A9P6MRF9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001906</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001451">
        <property type="protein sequence ID" value="KAG0009955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRF9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="228"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0009955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="248" mass="27582" checksum="79C7B6E1251E3424" modified="2023-09-13" version="1" fragment="single">MTNTLSKSLESPTSDAVEAAGNNPIQSSEKGMSTPLRKSKRISRSINAPGPVSEVEGNPKAHGHKETENITSDERQGRMASMNEKGKENIPPCEDGYKESRPGDNITSLENASQQHQGRTKRRKFSRPTRVVKLDDQQYEPDGEIMSSNSIDGGVDIPGPDTINKKDWEEKVPQKLESASHNVRTAGSGSRHKQEELSEYERQRLENIKRNQEMLRFLELPIAATSKHAIFKESEPGDKMKSSAEDLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRP8</accession>
    <name>A0A9P6MRP8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_000788</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001173">
        <property type="protein sequence ID" value="KAG0011293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRP8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0011293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="516" mass="58893" checksum="D02C473FBAA38F04" modified="2023-09-13" version="1">MHSTVTLRREPRPERIDIGDGLIMRWSTPQDKDNLADCLADAFRWETSGRRIPECGIPNKHEYISAAIGRLMSGKHVVQSQYDIALVEDTTRPSQGKNPIVAAVCMHQMAGYYGPIDITYGTLGAVGSLPEYRNRGLIRRLLFGYEYAVPHKFGRTLKHIASSIPALAAADPWKNGDGVTPVGEPFRLREVTALDIPYLIEMSTPDRLHCNSQLGLYYGKDFWSYIVEALKPELIENHHDAHHHAGIIVDIKSGKDIGISLTSNITGRWTWEAFTLNEELFTFRDVAYSVLRQLKAFDRPYYECYNAKLNNNILPDESETSKRERGEFSPLTFTDLVVNLTKHHPVTKILESQGKLAPENPPFRLYTRIHSLPKWIRKIAPVLEERLKDSVLKDISARIQLDFYRKLEGMSGRGLEIVFDQGKFVNAEDWAPKTPIQIHQESLLQEKEDLSSIKKQETVFSAGFAPMTFTRLVTGTMDVSELLERDSENYVQDGETKLALEILFPKFDHFVDLFWW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRX9</accession>
    <name>A0A9P6MRX9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_000604</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001128">
        <property type="protein sequence ID" value="KAG0011539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRX9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027850">
        <property type="entry name" value="DUF4504"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31366">
        <property type="entry name" value="UPF0739 PROTEIN C1ORF74"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31366:SF2">
        <property type="entry name" value="UPF0739 PROTEIN C1ORF74"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14953">
        <property type="entry name" value="DUF4504"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="199"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="290"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="345"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0011539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="475" mass="53665" checksum="C91D1EF876C5A94D" modified="2023-09-13" version="1">METMDLGQSCFQDALQLVRTALNDRLNLSAQTTLANEILCVAIGLRSASLIECLTLNEKDIAVFLSLFRQASVKGLHNLDILTIGSNDNNFVIHRGLLLQDIQEYLSHNPKSIRRLFVDVNHRLAKPEILPGNRCLLLEEYVRDILKPEIESRVTSCQREGFRRNRLPTPSKISNVTLTEWLLSYPIIYVLPKTCAKAPKQKQQQERYPGSFPYETGNGKHERGDGGDDGDDDEEEDDEGACGRNCLADRDLVVTNVRLEPNKDVEGLTDHSMISFSYPAHLAESCQTIEFPPKPSERTRGGIIGDGIDDDGDDDVFVDASDVEYQSRSGSLNLSTLKKPLEPDCFPDSVHLSQNNPPEHPSDPYKTHHYQPQPQSNSRVTRRNLSEEPHSLLVREQLSALKEKLQLQKAVEHASMPASDSYNRVESESPFPKREDVFTAGRSFLLQMHHRFKRQQVFKTWEVDQQTVNLPVVGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MS38</accession>
    <name>A0A9P6MS38_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">ABC-2 type transporter transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_001261</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001285">
        <property type="protein sequence ID" value="KAG0010685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MS38"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050352">
        <property type="entry name" value="ABCG_transporters"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041:SF2">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="170"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="203"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="246"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="286"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="320"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="400"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="domain" description="ABC-2 type transporter transmembrane" evidence="8">
        <location>
            <begin position="152"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="79"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0010685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="426" mass="46691" checksum="AFA6CDC15AC55E60" modified="2023-09-13" version="1" fragment="single">PRSDIFFMFDQALVVSKGEALYFGPADTAAEYFNRRGLVCPTNYNIADYLLDIAMDQELVAKAKSYQGSDLDEKAAISTGHQTHAPGNNISRRGVNGNSSDITRTSLTSNEQSYETAVRIDSGSIDNNSTASGSDSVSGKKLKTVYPTSFLTQLQVIMKRNFQTLVRDKSLLVLHVAVAIILGLFIGGLYFKVTMALAGFQNRAGSLFFMLALLGFSSISALGAFTDTRTLFIKERSNGYYPPTPFIISTLIFDLIPLRIVPAILLGCISYFMIGLSAVVETFFKFLLILVLFNISTAMFCLVIAAGVRATGVASLASSIVMLFMMLFGGFMINSGNIPAALTWIQYLSMFKYGFEALAVNEVATTHLVDTIQGVAFNVPGSLILQKLFGFSLGGYWKNMIILIGFNILFIILFWAIVTLRLKERK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MS97</accession>
    <name>A0A9P6MS97_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transmembrane protein 198</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_000555</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM198 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001115">
        <property type="protein sequence ID" value="KAG0011619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MS97"/>
    <dbReference type="OrthoDB" id="102260at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025256">
        <property type="entry name" value="TM7S3/TM198-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040236">
        <property type="entry name" value="TMEM198"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31247:SF5">
        <property type="entry name" value="DUF4203 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31247">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 198 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13886">
        <property type="entry name" value="TM7S3_TM198"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="166"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="190"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="215"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="261"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="TM7S3/TM198-like" evidence="9">
        <location>
            <begin position="85"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="15"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="388"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="23"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="408"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="421"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0011619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="473" mass="51551" checksum="654B8BC1225E7751" modified="2023-09-13" version="1">MGYFRSGTTTATITTGEKSKTLSTTSPHSQPYSSSRSRSMVVADAYPGLYRSAVSNDTADNNYDEPLILDVGQRTVISSQDKALGTIMMFFGALLVFFGYRLIRVTLLIMGFLTWAVIAVIIMAIVHWDMVSIFFHPAQYYFWMWFLAGLAGALIAFRFWDLGVMFIGGFGGFSLAMGIIAACNTSLSALGRYLVLVILIIFGAVISTYCERVSVIFGTSFSGAFLLMYGLDEFLQQGYREMFAIFGFTGRMLSYHPNKAVYTMIEASLGLACLGIIFELVFHKKPLWMDQKALFSVCGQPFGERPDMLMGQKVTHKIFYSSSSKPEYKTTDEAAYGGGYNNNYNYNYNNDNLGATRGVVGFNSVDQNRHLPSVPEAESNSLSSFATIQGRQGSGKGSGVSGAENISDVETITPGNSGALSKSSSTRTTQTTHTHEEQAGAGAGSVAAVSIQMPVEEENMSRDGNSFENVVIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSN5</accession>
    <name>A0A9P6MSN5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_000120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001019">
        <property type="protein sequence ID" value="KAG0012215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSN5"/>
    <dbReference type="OrthoDB" id="445983at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="108"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0012215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="192" mass="21507" checksum="1DAD21EEF2562D5D" modified="2023-09-13" version="1">MSAVAPTLARSTVSKLYREVDVYGEWVDVCEEINNSVKAKQGQDNETTTLKPSSKHPVVEDPDAIQRISMDMECTHIQSQAQSNTSTPKLNQAQTRVYSRSKNRPTPTAATATTASGQQQQQQKLKEHQRKHIEKFDQTSVQVKGKGVMTFDDLEWDYSILDEADLGSDRGMDDDDDEDHYDGSGSYIEFGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTD8</accession>
    <name>A0A9P6MTD8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Bud site selection protein, Revert to axial protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RAX1</name>
        <name evidence="4" type="ORF">BGZ80_000233</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001041">
        <property type="protein sequence ID" value="KAG0012063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTD8"/>
    <dbReference type="OrthoDB" id="5584247at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008104">
        <property type="term" value="P:intracellular protein localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.167.10">
        <property type="entry name" value="Regulator of G-protein Signalling 4, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052246">
        <property type="entry name" value="Cell_Polariz_PKAAnc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036305">
        <property type="entry name" value="RGS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044926">
        <property type="entry name" value="RGS_subdomain_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13155:SF1">
        <property type="entry name" value="A-KINASE ANCHOR PROTEIN 10, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13155">
        <property type="entry name" value="A-KINASE ANCHOR PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48097">
        <property type="entry name" value="Regulator of G-protein signaling, RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="667"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="696"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="752"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="146"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="356"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="456"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="558"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="271"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="191"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="359"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="457"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="558"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="575"/>
            <end position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0012063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="775" mass="85918" checksum="05F74746BB4C7597" modified="2023-09-13" version="1">MSNANSFSNTSSSLSAISTTSSTSRKQPPRHLEAIQTQKAQASTSFLPVSTTRNGGDDITQYPSYPPHSGQQTQHGIVGTGTEMMYSEQPLATAATANDGFPFTPSTLVGGILSPVEYHHDYPGQHQKAHIRTSGTLPRRQIQHQYDTSSISDNAPFRASMSSNRQTRHADNLSSSGSSTNGRNGGRYGTRRQQGVAPTYSSSSDDAQSQQLPTLWQVLHRKTVPPVCLFNFYLYMRDYEKSSEEVDFWLDVTAHEVLWRLYVRATKRKQALAAQERSEREEREVARLEAERWKAQMEEEQEKELKKGHQQKHSINLAMYEPHWSAVNRYLEMSEAESDNLSNTGASMTETGSHYNHLQQQTQHQQQYQSSDMTQLSSMQGSDVLTLTVNESTASFPSPNSTTREVPVLPGAVSNNWSHLEDEDIRSKNKHGTGICTASSVSGLSTSTVDVLTAKETTVDGREKGTGTEGASDHQSGTMGTLTTAKSMNVKRGLATSATSPSVTKEDLQRSAERIYCKYLVPQAEKPVRIPGSVRRRVAQVMDSVMMINADEIIANNNNNGNVATTTFSPSSGMETVSKSKSETPSSPSMVSLNSPRNEKLSPAQKQEVRQSMVSQSSFHQPDQDLGLVFAEAREIVFEGMESYYFPRFLKTRAYGNMAHSHRVARAVLGLFILFIGFVIVLCMIFLNLRPRSVRAWALIPIYIGILLCTTFQFNICPLIAAFGVSETRWMKFAEIKEPNILALHRKRATKVLVVSLLYTICVGTVFGLVPGHRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MU47</accession>
    <name>A0A9P6MU47_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nucleolar protein Dnt1-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_010963</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000823">
        <property type="protein sequence ID" value="KAG0013613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MU47"/>
    <dbReference type="OrthoDB" id="2446486at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="512"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="111"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="205"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="254"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="270"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="306"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="332"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="460"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="512"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="590"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="615"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="626"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="652"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="697"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="710"/>
            <end position="721"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0013613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="721" mass="76412" checksum="17731A559F60AD79" modified="2023-09-13" version="1">MATPYRLNVRINSDRSSTNISPSERRFVTLADAELSIRDLKKEILKDYRKHFALDAKYYMIDRLENRDFFALNDNHTLQQVLEPVDIVNVVGQFKKAKGTKADQATEEKAAPTTPSSTAATTTTTTTSNANTDVTKKKVVPKTGEPSKASADSTAAPAKKRKHVEDGASTRSQKDVSSATPTANSTDAAAVNKRQKKKTTQETDAASGTKTASTATTTSSATKKVKVASSTSKSGSVNSSQSEEEIMKKISAAAKEKKATESKDQDKPVETSSPSSTTATTTPSATTTSATAESSAKKQKKKPQEEQTPATGTATGTATATKIKSKIAKPQTEQEKTAEKTAEKNTEKTADKTGKSEKEKAGKGEKVNGVSKDSGAPQEGGAAETTASLSKNAVKKAKKIAAAKASKADSEGSEAEEKEDSSLKQKRATYTHPDGTPMTSEEKHAAKLARRREREKAARAGKAAKLASSATSDENGSGSDSNNNNGNNNNNEIKVIVRRASRNLDNDAILKELLSKDPSELTDQDKREIHLAERRKKEKEQREAHKKALKDIESDDPEVVAAAREVLLPKKKGRPGKLDKDGDSEMNDNADGQHSKSLSTSSPIPQVSTAPKQASSESSSSSSSESGDRTSSHSAESAKVRIPKFVGKDNDSDSDSDGDSDSGSDGDSDSDSDSDNNTNNMKATGSGGLVGKMTFLSTPPSDSSSTSSDSSDDFDESSDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUG4</accession>
    <name>A0A9P6MUG4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 9">RNA polymerase II subunit A C-terminal domain phosphatase</fullName>
            <ecNumber evidence="2 9">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">FCP1</name>
        <name evidence="13" type="ORF">BGZ80_011429</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">This promotes the activity of RNA polymerase II.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 9">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="2 9"/>
    <dbReference type="EMBL" id="JAAAID010000919">
        <property type="protein sequence ID" value="KAG0012900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUG4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008420">
        <property type="term" value="F:RNA polymerase II CTD heptapeptide repeat phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd17729">
        <property type="entry name" value="BRCT_CTDP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07521">
        <property type="entry name" value="HAD_FCP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10190:FF:000007">
        <property type="entry name" value="RNA polymerase II subunit A C-terminal domain phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.10">
        <property type="entry name" value="S15/NS1, RNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039189">
        <property type="entry name" value="Fcp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011947">
        <property type="entry name" value="FCP1_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02250">
        <property type="entry name" value="FCP1_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23081">
        <property type="entry name" value="RNA POLYMERASE II CTD PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23081:SF36">
        <property type="entry name" value="RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FCP1 homology" evidence="12">
        <location>
            <begin position="118"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="11">
        <location>
            <begin position="407"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="269"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="500"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="575"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="304"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="500"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="583"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="652"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="711"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="732"/>
            <end position="748"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00040602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU366066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0012900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="768" mass="84450" checksum="3A7BC8D58FAE9F93" modified="2023-09-13" version="1">MSSEDKICHSIPAKFLPATIISIKTSEGKTQSEGDELIEYEYMENVEGFIDEGQTSSHARRSEIRANKDGIVKTILVAKGQVIDDARSHVNMTHDATSLTVSRGEAKRLELDNVERLLGEGKLSLIVDLDQTLIHATVGTAIDEWVNAQGKMPEDIKMFPLPDSPTPYYIKKRPHLDDFLQKLSSMYELHIYTMGTRNYAAAVANVIDPDGKLFNMTQKSIERLFPCDTSMVVVIDDRADVWRYSPNLVKVHPYEYFVGTGDINAGHLPKQEKSVRTEPASVPTASDPGTLATNPSNPPSDAANTSDTPNTSNKSTNSDSATTSDTTAAPDTPIAPPKEPITTPSKPDDANKISKPKAPVMDDNDDELIRVLKILEAIHEQFYDNRENFIQNRSTKKADVKAIIHSMKSEVLKGVNVVFSGVIPKHQNPEKTDIWRQADGFGAHCLHEVDSRVTHVVAAQLGTEKVMKARRRKNIKIVRPEWLYHSIAKWKKQDEAQYSFQDASGKSTSNSTTPPILTEGEEDIGIEDDDLGGISEGMDENHHPLSINNDEINEHLKSVNWDDMEKEVQELVGDMDESDFDSDTSTRSNTQSDASTDGNGSPFINLKRARIPRKSGLGATVTYGSSDDEDDNDSISNGLGMDGLQGTNDAANSDESDGEIDEESGSDGDDESQGGSEVASDAERPTRPLKRRRIDGGNGKQAARAGRDSVDEGIDADDEITMDHSTVYLDSQGDDDSDGGDDEEDDDDFLNFMENDIEAQLQEDNNDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUG9</accession>
    <name>A0A9P6MUG9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Hsp70 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_011534</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000939">
        <property type="protein sequence ID" value="KAG0012752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUG9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10229">
        <property type="entry name" value="ASKHA_NBD_HSP70_HSPA12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187">
        <property type="entry name" value="ALPHA KINASE/ELONGATION FACTOR 2 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187:SF5">
        <property type="entry name" value="HEAT SHOCK 70 KDA PROTEIN 12A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="47"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0012752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="684" mass="75697" checksum="E7740083BB08B6B8" modified="2023-09-13" version="1">MVFTSLSGTPAVTQPPPSQQNGSNGAASYGGGYPPVSGGGYPPVSAPPSSHYGYNGQQQQQQQQYPSMPQPPSHQQQGGIAPPPSSSNAMYPPARQPSIPQPNASSQYQGQPYNPGYMATSAQQPELTRANGSRLTGDPKEDYPIVMAIDFGTTFTGCAFAFRKDPEIQEIITWPKQAYQYPKVPTISLYKLDSPEFLDWGYPARAVMMTPNAKKHLLLSKFKLQLDDQQEHIDPLPLGIKPLDAISDYLGKFHTHVVKEAMKNFGSTYDQSHIQYCLTVPAMWSDRAKHVMRLAAVRAGLIREEDPAHRLIIVSEPEAAAMYCQSKGDQFNLQKHDRFLICDAGGGTVDLIVFEVVDVNPETGIRSLREVTRGHGASCGSAFLDANMEKLLREKFQKYPLTPMGWGTIMDTFVNQTKPIFPGTDPEMYLQVPNIPNLPDANDLDIGLEDGMLKLMVSELHERVFDPVVQDVLDLIEYQLQQTHCEAIFMVGGFGSSRYLFDRVTAKFATSGRQVRVPPRAELAVVRGAVTYGLHQGSIISRVARRWYGVDSAMDFVPGVDPEEKKTLSRDGTVRCKDRFSVYITPGQSVALGECVTKKYMTWCYPRPLDCPLYVSDSEQEPRYVDEPSVKKLGDFQIPMPDVPGMMPGAEVLVEVKMHFGETEVRAEALVLGQTVTAVCQWIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUS4</accession>
    <name>A0A9P6MUS4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Catabolite repression protein crec</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_010393</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000719">
        <property type="protein sequence ID" value="KAG0014514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUS4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051286">
        <property type="term" value="C:cell tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045013">
        <property type="term" value="P:carbon catabolite repression of transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051362">
        <property type="entry name" value="WD_repeat_creC_regulators"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14107:SF16">
        <property type="entry name" value="AT02583P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14107">
        <property type="entry name" value="WD REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="435"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="88"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="526"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="601"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="97"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="139"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="605"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="631"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="658"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="669"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="728"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="745"/>
            <end position="764"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0014514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="825" mass="89975" checksum="ECED4C54457C70CA" modified="2023-09-13" version="1">MATSALSPVQECREFVAAEGRYELCQDIFLDNVQAHPAIPTYVSSVSVRYKDYFGDLTGKQDGAEGVISALNIDQLDEQLKDLNVTDERTADDDESSIGNTNTSTPRLSGNFHGNLVNLPLYGDEGSESKTPKNGMLSPGPPQVVTPGPPPLKDSTYSRRFSEVLPINHQTISAFSAKRLGRAASFSHQPLHMQEEGNGQIPPYATIGPSSASSVGFSSFFSGKRKKPKNNIAKTNSTFVAKITTNENLSKILANRVNEDVYVFWNIGRTFSWSDLGQKPNEPLSHISFTKAFPTAHDVNILTRSCDHLDVIIGFSTGDIIWFNPLSNKYSRLNKQWMPGSESQFMASFQDGTMVIMDKDRDDNTFSPSNPPFENSFHATKPKSGRHNPITHWNISKKPVTAFAFSPDLQHVAAVAQDGGLRIIDFRHERLIETFQSYFGALSCVCWSPDGKYILTGGQDDLVTIWSFKDLRIVARCQGHHSYVTGVAFDSWRCDEQNYRFGSVGEDAKLLLWDFSVGALHKPKAANMQRRGSNGTIHGGGAFKPGHRSKGSITSLRGHGGHSLFSGLNKPSLSQQMTLTYDHASNKDVAVDPVTSIQEGASKAVSSNVTPSISSSPIGKSSCVTLDAPPLSANSESTSISAETSSMLSTAVSEEIGDGSSSNNGNDDQQSVSTTSGSNITAEEKPRRRRSVFKQAKELPPLQIQHQHANNSSNGGGGGGTTAANNSKSGENSQGNGISSLFYSQRQQQQQQQQQQQQQQQQQQSEPVMRPPEPRSHVAMLQPLMAVAIHNEPLASITFREDAIMTSDRRGHIKVWKRPSVGHAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVB1</accession>
    <name>A0A9P6MVB1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Peptidase M48 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_010965</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000823">
        <property type="protein sequence ID" value="KAG0013615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVB1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034982">
        <property type="term" value="P:mitochondrial protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006515">
        <property type="term" value="P:protein quality control for misfolded or incompletely synthesized proteins"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07324">
        <property type="entry name" value="M48C_Oma1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2010.10">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051156">
        <property type="entry name" value="Mito/Outer_Membr_Metalloprot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22726">
        <property type="entry name" value="METALLOENDOPEPTIDASE OMA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22726:SF18">
        <property type="entry name" value="PEPTIDASE M48 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="41"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M48" evidence="10">
        <location>
            <begin position="250"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="226"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="174"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="226"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0013615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="494" mass="55976" checksum="FD4B159EEFF667C8" modified="2023-09-13" version="1">MHTSGTAHLQSRQQVQQVLLNNRSSGLQQVSRFHTSRPNQLPAPLLPAALFTLKTPVTALVLRMISRASLTLLPLSVKRSPKIILALVITPPVCFALVIFAGLEAAPNTGRWRFLFTGEEEELSMLQDEIPVFMESIKVVDSEDPRVQLVRHILENLLSSSIERDGSTLRTGIVERLEKKHEEAQQRLKELQQRTAASEAEANGNNDDAANQAGAAVAAKAIVSTQKPVSTNSPVTHPEEEEEEEDPELAAITFEDRPFQIFVAEDDAINAFSLGPPRLIFINSGLMDWLENDEDLVAAVVAHELAHVIQRHTMETHGRETVMLIEVEADTVSLTLMALAGYDPMHSVRLWELWADKDQREMDDDEKEVHKWTDWMYDHPPSAERARYLKESVMPAREMWEKVLKRRKEPMKRFLSLDNRMKSQVDEDGDLKEGTVEDILETMDELLKQQQEEEEAAKRQSGFMGFLRKWAGWRPWRPMANQDMDIGSGEPVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVD6</accession>
    <name>A0A9P6MVD6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ammonium transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_010563</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ammonia transporter channel (TC 1.A.11.2) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000749">
        <property type="protein sequence ID" value="KAG0014233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVD6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008519">
        <property type="term" value="F:ammonium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3430.10:FF:000011">
        <property type="entry name" value="Ammonium transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3430.10">
        <property type="entry name" value="Ammonium transporter AmtB like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029020">
        <property type="entry name" value="Ammonium/urea_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001905">
        <property type="entry name" value="Ammonium_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018047">
        <property type="entry name" value="Ammonium_transpt_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024041">
        <property type="entry name" value="NH4_transpt_AmtB-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00836">
        <property type="entry name" value="amt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43029">
        <property type="entry name" value="AMMONIUM TRANSPORTER MEP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43029:SF10">
        <property type="entry name" value="AMMONIUM TRANSPORTER MEP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00909">
        <property type="entry name" value="Ammonium_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111352">
        <property type="entry name" value="Ammonium transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01219">
        <property type="entry name" value="AMMONIUM_TRANSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0924">Ammonia transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="17"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="138"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="177"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="205"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="237"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="268"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="295"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="323"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="371"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="domain" description="Ammonium transporter AmtB-like" evidence="10">
        <location>
            <begin position="18"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="464"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="517"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="483"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="517"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="545"/>
            <end position="558"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0014233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="558" mass="60071" checksum="3AEA98D516CD1C3B" modified="2023-09-13" version="1">MENSTVVASSDYKPGDIAWVLTSTALVFLMCPGLGLFYAGMARMKHSLSLMMLSVLAVAMISIQWYFWGFSLTFSATGGKFIGNLDHIVGRGIGWEPHPSAPNIPSSAFFLFQLMFAAITPALAYGASAERMRIMPSILFLFLWSTTVYDVITYWVWGPNGWLNTMGVMDYAGGTPVHISSGSAAVAYAMVLGKRKDYNHPSTVPHNVAFVFIGTALLWFGWFGFNGGSAGAANARGIQTIINSHLSACVGGLIWVFMDYRHNKKLTLIGFCTGAVAGLATITPGAGYVTSSSSLVFGLVGSVVCNLCVGWKSKFGFDDALDVFAVHYVGGLIGLLLTGIFAQQKVIALSYPPGATDVPIGGWLDGHYSQILVQMAAIGSVTAWSFVVTYGMLYLMNKVPGLRLRLKDHEEEMGTDIAQMGESAYGFAPLLHNIHHTSIRTEDEESNIGSISKNQDTVNSTIRLGDLPVHRLTGRNSTPPGKAGVNTSNVGSGGSATTPTATNVSSETLNLDLYVLRPEESQDHPKRLPPMTESRRGSVACSNQYHEDTSDSEHDQDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVM3</accession>
    <name>A0A9P6MVM3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DASH complex subunit ASK1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">ASK1</name>
        <name evidence="17" type="ORF">BGZ80_009901</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
            <location evidence="3">Centromere</location>
            <location evidence="3">Kinetochore</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Spindle</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DASH complex ASK1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000636">
        <property type="protein sequence ID" value="KAG0015353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVM3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042729">
        <property type="term" value="C:DASH complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072686">
        <property type="term" value="C:mitotic spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044732">
        <property type="term" value="C:mitotic spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008608">
        <property type="term" value="P:attachment of spindle microtubules to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013964">
        <property type="entry name" value="DASH_Ask1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28200">
        <property type="entry name" value="DASH COMPLEX SUBUNIT ASK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28200:SF1">
        <property type="entry name" value="DASH COMPLEX SUBUNIT ASK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08655">
        <property type="entry name" value="DASH_Ask1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="8" id="KW-0132">Cell division</keyword>
    <keyword evidence="15" id="KW-0137">Centromere</keyword>
    <keyword evidence="6" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="11" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="9" id="KW-0493">Microtubule</keyword>
    <keyword evidence="10" id="KW-0498">Mitosis</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="90"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="148"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="333"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="399"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="607"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="663"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="720"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="783"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="97"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="189"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="363"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="399"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="420"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="613"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="663"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="677"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="720"/>
            <end position="740"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0015353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="811" mass="86038" checksum="EE3D8F48A1813195" modified="2023-09-13" version="1">MASSLRSTADVLDEIERLEQSITRTLQEIDQSFSDCQIIVSSKILPQIDRYAETSQGVWEHARLWLNFFEAASTTAAPTVGPRAQAVRDARNRQQTEMKLGNTQSEPTTPEYAGLSVPRSPGYDNLEDNSTNRQRIDLSSSRLSLDFLGSSPLGSMPSTPTPGRGGRKISQYLGDIAPPAAINWPDLQSGDNAHSTPTRQPYKFNTTAAEKESTTLSVTPKDRPQSIPTYTQPNPPHTPLGNRRQSHQGTSHPRRSQDGGFVEIDLEGDHQDVITPPSTLHFSIPESKLATTPRSVVAKSRIDTIHMKDGLVIPQPIFVNDDDDDALIADKYVGGSISGSGIGGSKKRSREGDLHDPEEDDPNSQPNGWASLTDQQRNIERLLKSPRKMASVQDFFAPSQTQAAAAPSSSSSSSKSASDTGKKQQREESKDTNGDGQSPSRDLISQIEAQADQTEEDPLIAALATPPETRKAIMDRKARDSLLPQLHATSSTISSSSSSSLLSKVSAPIFSMPGLARSISGTTPNTTAVSTTSVQESLLTTVPTGTNGADSSVARSTSSTIGATFMESFNSAFAATSNRRQTMATPIARSNIFSSASLGQYSRNSIGPGYRPNLTSAPFGSPRSAGSTNSRLSLLGSTRHHPVEPTSAGKVAASIIASAAAATSSSSNSRTSSQANELNGSTRQASQSGLDKFTFGAGSNTIATGILSTPVVSTTSMLAQGQDYPSTSSSTGSAGQVSNARDSDFPSGGFLTPFTNRNPPPAPRLGYHSDTIMTQSSLGLNHDGFGFDSEDRTRMTMASNSSGISDGELNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVW5</accession>
    <name>A0A9P6MVW5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Protein tssc1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">TSSC1</name>
        <name evidence="7" type="ORF">BGZ80_009762</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat EIPR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000612">
        <property type="protein sequence ID" value="KAG0015601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVW5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059104">
        <property type="entry name" value="Beta-prop_EIPR1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040323">
        <property type="entry name" value="EIPR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14205:SF15">
        <property type="entry name" value="EARP AND GARP COMPLEX-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14205">
        <property type="entry name" value="WD-REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23609">
        <property type="entry name" value="Beta-prop_EIPR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="EIPR1-like beta-propeller" evidence="6">
        <location>
            <begin position="114"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="122"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="193"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF23609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0015601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="270" mass="30670" checksum="73A36C4DF340BC12" modified="2023-09-13" version="1">MKQDQKDSEEMDLDRPHHHQARGELEHVLTLDGDGTVKKVIWQDSTEVISVEDWRIYIWDIDVKQGTAKVRRRGCLTGSIETPDKNFKFTSAVMNPHAKEVVAVYGRSIQGWNLNSLKPFQIATGGDDCKVRIWDVRDSTAEPIMTIQDHTHWVWSVAYNKFHDQLVLTSSSDCQVNLQSIVSISTGAEYKYGDASDTERDPADEDDQVENVSHDAPTDGLVQAFDQHEDSVYQVAWSSVDPWLFLSLSYDGRAVMNQVPSEEKFKIILN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MW57</accession>
    <name>A0A9P6MW57_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_010127</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000672">
        <property type="protein sequence ID" value="KAG0014979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MW57"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0014979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="236" mass="26638" checksum="478DA295FDF0D97A" modified="2023-09-13" version="1" fragment="single">MFDAFPVKFKFSNSKKVLALRVITIVAFGLITFCNFISTCSSYYSPTFNNECAKALITPGAQLRYPRFMMMTDSQALYDGNSVTDCSLRDVIIQMLLAAPQAPSFTLNMNMDCSNGISIFVYDITFTFWDQYYGLIATSATNYKYYTAIPGWPFDAVEFKQNWTTSASDNNMRFFFGNYTYTMPPQTVAPGHAIFDTIMNSAIQDVQDNAIPGVKYLCSQCGVQANWKGEKFALIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWM8</accession>
    <name>A0A9P6MWM8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_009153</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the indoleamine 2,3-dioxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000525">
        <property type="protein sequence ID" value="KAG0016536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWM8"/>
    <dbReference type="OrthoDB" id="10262710at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016702">
        <property type="term" value="F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:L-tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.480:FF:000005">
        <property type="entry name" value="Indoleamine 2,3-dioxygenase family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000898">
        <property type="entry name" value="Indolamine_dOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037217">
        <property type="entry name" value="Trp/Indoleamine_2_3_dOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28657">
        <property type="entry name" value="INDOLEAMINE 2,3-DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28657:SF3">
        <property type="entry name" value="INDOLEAMINE 2,3-DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01231">
        <property type="entry name" value="IDO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140959">
        <property type="entry name" value="Indolic compounds 2,3-dioxygenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="508"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="44"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="binding site" description="proximal binding residue" evidence="4">
        <location>
            <position position="446"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR600898-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0016536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="535" mass="60349" checksum="DD10289733710897" modified="2023-09-13" version="1">MLRQTLFRQTNNILKHAPAQTSTFAAAAISHSLRLQAQAIREYSTPSAPSSSSSASQGQPKYRQFHTSDINQQAREVPGFPILDDPLTHNHSIPSFMVGTQNGFLPRQDPLDVLPKEYDALEQLLQKMPLTLKDGSKGLLALGQFGEACKSLPQYDLSNVEDSELLSALYRDYTFVASAYLLEPCDLLYRKTGDYGLGRSVLPKNIAVPLVQVAEKIGAKPFMEYALSYALYNYRRIDKSKGLVWGNLELIRPFSGDKSELGFIISHVTMVSHSGELVKNTMRTLDAATKCNREMFNDALSKVVSTYEKINMEMDTMWERSLPADYLKFRTFIMGTKNQPMFPNGVIYEGVSDEPMFHRGESGANDSMVPMGDNLLQLTENMPSNPLTAVLKDFRTYRPHNHAEFLQFVEEKARQVHVRHFAEQDPNSAAIYLAAVDQIRNFRNRHWSFTKEYIIKYTKHPVATGGSPIVTWLPNQLATVLKTMQEVGSKIDANQLLPENKALVDVLSKRADAQARILEREVAHLRTQIKDQDKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWX1</accession>
    <name>A0A9P6MWX1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Protein transport protein SEC23</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="primary">SEC23_2</name>
        <name evidence="20" type="ORF">BGZ80_009726</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="14">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 14">Cytoplasmic vesicle</location>
            <location evidence="1 14">COPII-coated vesicle membrane</location>
            <topology evidence="1 14">Peripheral membrane protein</topology>
            <orientation evidence="1 14">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 14">Endoplasmic reticulum membrane</location>
            <topology evidence="2 14">Peripheral membrane protein</topology>
            <orientation evidence="2 14">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="14">Golgi apparatus membrane</location>
            <topology evidence="14">Peripheral membrane protein</topology>
            <orientation evidence="14">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the SEC23/SEC24 family. SEC23 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000608">
        <property type="protein sequence ID" value="KAG0015643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWX1"/>
    <dbReference type="OrthoDB" id="10256289at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030127">
        <property type="term" value="C:COPII vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070971">
        <property type="term" value="C:endoplasmic reticulum exit site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090110">
        <property type="term" value="P:COPII-coated vesicle cargo loading"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01478">
        <property type="entry name" value="Sec23-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11287">
        <property type="entry name" value="Sec23_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.730:FF:000001">
        <property type="entry name" value="Protein transport protein SEC23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.380:FF:000001">
        <property type="entry name" value="Protein transport protein SEC23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.20.10:FF:000006">
        <property type="entry name" value="Protein transport protein SEC23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.410:FF:000008">
        <property type="entry name" value="Protein transport protein SEC23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1670">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.730">
        <property type="entry name" value="Sec23/Sec24 helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.380">
        <property type="entry name" value="Zn-finger domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012990">
        <property type="entry name" value="Beta-sandwich_Sec23_24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007123">
        <property type="entry name" value="Gelsolin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036180">
        <property type="entry name" value="Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037364">
        <property type="entry name" value="Sec23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006900">
        <property type="entry name" value="Sec23/24_helical_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036175">
        <property type="entry name" value="Sec23/24_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006896">
        <property type="entry name" value="Sec23/24_trunk_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037550">
        <property type="entry name" value="Sec23_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006895">
        <property type="entry name" value="Znf_Sec23_Sec24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036174">
        <property type="entry name" value="Znf_Sec23_Sec24_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11141">
        <property type="entry name" value="PROTEIN TRANSPORT PROTEIN SEC23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11141:SF0">
        <property type="entry name" value="PROTEIN TRANSPORT PROTEIN SEC23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00626">
        <property type="entry name" value="Gelsolin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08033">
        <property type="entry name" value="Sec23_BS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04815">
        <property type="entry name" value="Sec23_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04811">
        <property type="entry name" value="Sec23_trunk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04810">
        <property type="entry name" value="zf-Sec23_Sec24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81995">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82754">
        <property type="entry name" value="C-terminal, gelsolin-like domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81811">
        <property type="entry name" value="Helical domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82919">
        <property type="entry name" value="Zn-finger domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 14" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13 14" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="7 14" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 14" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="11 14" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="12 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 14" id="KW-0653">Protein transport</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 14" id="KW-0813">Transport</keyword>
    <keyword evidence="8 14" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zinc finger Sec23/Sec24-type" evidence="16">
        <location>
            <begin position="53"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 trunk" evidence="17">
        <location>
            <begin position="122"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 beta-sandwich" evidence="19">
        <location>
            <begin position="400"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 helical" evidence="18">
        <location>
            <begin position="515"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="domain" description="Gelsolin-like" evidence="15">
        <location>
            <begin position="628"/>
            <end position="715"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU365030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF04810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF04811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF04815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF08033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAG0015643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="763" mass="85312" checksum="50834EE96A331A40" modified="2023-09-13" version="1">MNFEEIEDQDGIRFSFNAWPASRQEATRAVVPIAALYTPLKEREDLPLIYYEPVTCKQNTCGAILNPYCQIDPRGMLWICPFCLHRNQFPPHYRDISNTNLPAELLAKHTTIEYTLARSAQVPPIFLYVVDTCIDEDDLKALKDSLVVSLSLLPPHALVGLITYGTMTQVHELGYNECPKSYVFRGNKDYTCKQIQEMLGITAQTMRPQQPVRPGQPAPFVPTGNSRFLLPIQQCEYTLSSILEQLQRDPWPVATDKRPLRCTGVAMSVAVGLLEATYQNNGGRIMLFVGGAATEGPGMVVGADLKEPLRSHHDIEKENVKHYKKASKFYEGLAKRASTNGHVIDILGGCLDQVGLLEMKSMVNSTGGFMILTDSFTTAIFKQSFQKMFDKDAEGNLKMGFNATLAVQTTKELKICGLIGHAVSSNKKTASVGETEIGIGNTSAWKMCSVTPLTTNGIYFEVMTQQGQSLQPGSRGLVQFVTHYQHSSGHFKLRVTTVARSWAEGSSPIIAQSFDQEAAAVLMARIAVFKSEIDDGPDVLRWLDRMLIRLCQRFAEYRKDEPQSFRLSENFSIYPQFMFHLRRSQFLQVFNNSPDETAYNRHVLDREDVNNSLIMIQPTLMSYGFEGEPQPVLLDSVSVKPDSILLLDTFFYILIFHGETIAAWRNAGYHEQPGYENFKELLETPAVNGQELLMSRFPIPRYVVCDQNGSQARFLLSKLNPSTTHASGGQYGNAPAGQAIFTDDVSLQVFMEYLKKLVVAGTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXQ1</accession>
    <name>A0A9P6MXQ1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Prolyl 4-hydroxylase alpha subunit domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_008922</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000500">
        <property type="protein sequence ID" value="KAG0016808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXQ1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004656">
        <property type="term" value="F:procollagen-proline 4-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045054">
        <property type="entry name" value="P4HA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869:SF247">
        <property type="entry name" value="FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prolyl 4-hydroxylase alpha subunit" evidence="6">
        <location>
            <begin position="283"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0016808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="463" mass="51077" checksum="97B54EA4687B29B1" modified="2023-09-13" version="1">MGKAGKDRKRRRLLAEVSATGVGAHHLKVLDQENAGNSAATVAGGGDLDMNKSIGGVVSEEDMAITLRTLMTLEQHTEVFRSKSCKALRAVVHQLQQTATATTGMGQTPIGRISDALVDGRWNDAMTALEEMRTRGQIPKLGALQRWVRDCDAASAKSGAFGDPVVLRVLDSMLRTVDPSMIPKKEEEHPIRTHPMWQAFPRVEDNVQKYEAALNGTLCTKEDAERFKQSFRIVAHTKGPQRRTPNLHDFTLYLSNPGTIRLCYQDNPSAQPPVERIEMPHVPGAFLLKDVLTRKECLQMISAAESVGFTPDVPMVGSASESISVLAHNFFWMADDQLLGHIFDRCKMHFPETSGDGHGAVGINSRWRVYRYVPGAIYRTRWSRLTFLVYLNDEFEGGGTTFFTPSADFGFMDARANSPRAGSVLCFPHGEAAGSLLHEGSPVLKGAKYIIRADVLYEVPVRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYE0</accession>
    <name>A0A9P6MYE0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_007084</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000357">
        <property type="protein sequence ID" value="KAG0018502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYE0"/>
    <dbReference type="OrthoDB" id="2370938at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0018502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="223" mass="25999" checksum="9AFF3695A1438E62" modified="2023-09-13" version="1">MKDNGEKTLLEFLAVMADEDQDPVKFFEWAGYPSWNEGRAGAVWKTTLRGLDSEKAIVLETRWTESKERRKEYWKQLRRKEEADKKMEEWCERIENVNSAEKDIVIELQHRKFKAFVDNKISPFIAKGEPSPPYTPSHLPSKRLREDFTGGSESSWEVLTQGDIVDVLQEMRPQQHMGELLGVKREHVFSCVLDNVDVGALFTEYFKVCCFESYKHAYPEDAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZA8</accession>
    <name>A0A9P6MZA8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_007679</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000398">
        <property type="protein sequence ID" value="KAG0017981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZA8"/>
    <dbReference type="OrthoDB" id="1706066at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050218">
        <property type="term" value="F:propionate-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032387">
        <property type="entry name" value="ACAS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43347">
        <property type="entry name" value="ACYL-COA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43347:SF3">
        <property type="entry name" value="ACYL-COA SYNTHETASE SHORT-CHAIN FAMILY MEMBER 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16177">
        <property type="entry name" value="ACAS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acetyl-coenzyme A synthetase N-terminal" evidence="4">
        <location>
            <begin position="8"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="2">
        <location>
            <begin position="74"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="3">
        <location>
            <begin position="540"/>
            <end position="618"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0017981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="683" mass="74764" checksum="D002E448A9E76A42" modified="2023-09-13" version="1">MVPQTQAQVLQAALRDPDQYWDQFGSQLHWDTPYSKVLAFGEPSSASVGTDYTWFKDGKINTCYNAIDRHVLSGHGKQVAVYYDSPLNNERRAITYQELLEQVQTCAGVIASHGVKKGDIVLIYMPMVPEALVSMLACARLGVTHSVVFGGFAPLEVQKRISDSKPKLIIGGSCGIEVGKIIPYKEMLDKAIDMGDHKPTQKIIFQRDAGRTTLDASRGDLDWHSEMERIRRAGKQFKDWVPVESHHPLYILYTSGTTGLPKGVVRDNGGHAAHTLATMKNLFGANPGEVIFCASDVGWVVGHSFICYGPLLLGCSTILYEGKPIGTPDAGAFFRIIQDYKVSTWYTAPTALRAIRRVDPHGEFSNKYDLSSLRGLYLAGERSDHGTIMHFQKVIGGKPVVDNYWSTESGSPITAACQGLYDTNGAKVTPIEARQGAAGMPTPGYDVRVLADPDENGGAIKELGPSQFGNIVVKLPLPPSSLHTLWNNPAGFHKSYLSRFPGYYDTGDAGIVDEDGYVHVMSRTDDIMQVAGHRLSTGSVELILAEHPAISECCVVPLSDKLKGQVPMGLVVLKFGVTQKEEDILKETIQMVRQNLGAIANYNQTHIVRRLPKTRSGKILRRTIRDIIAGKSLENKTLVVPPTIEDVTVLNELEEVITKLGLVGNDGEAGKLDDTVKPLKSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZC9</accession>
    <name>A0A9P6MZC9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">beta-mannosidase</fullName>
            <ecNumber evidence="2">3.2.1.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_007112</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing beta-D-mannose residues in beta-D-mannosides.</text>
            <dbReference type="EC" id="3.2.1.25"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.25" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010000359">
        <property type="protein sequence ID" value="KAG0018478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZC9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004567">
        <property type="term" value="F:beta-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006516">
        <property type="term" value="P:glycoprotein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036156">
        <property type="entry name" value="Beta-gal/glucu_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054593">
        <property type="entry name" value="Beta-mannosidase-like_N2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050887">
        <property type="entry name" value="Beta-mannosidase_GH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041625">
        <property type="entry name" value="Beta-mannosidase_Ig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43730">
        <property type="entry name" value="BETA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43730:SF1">
        <property type="entry name" value="BETA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22666">
        <property type="entry name" value="Glyco_hydro_2_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17753">
        <property type="entry name" value="Ig_mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49303">
        <property type="entry name" value="beta-Galactosidase/glucuronidase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-mannosidase-like galactose-binding" evidence="7">
        <location>
            <begin position="38"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-mannosidase Ig-fold" evidence="6">
        <location>
            <begin position="629"/>
            <end position="665"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF17753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF22666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0018478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="738" mass="84193" checksum="9625EFE29E014F17" modified="2023-09-13" version="1">MSNDLKIKSEAAGVIRLHGEWHLSSLDKSVQTIASVPGSTNNQFRRYMFDVSTTLRAGSNLLRIQFESAVSYADAKAKEYPYYVPDMFNMSSAQYGFPCRNFIRKEQVSVEVSSVKIQRLSTVFKFDGGLPTSESTFSVNAGESTFNHSIFLKKSQVKLWWPRNYGQSTTYTVEVTLVNESGSKVASHVFQCGFRTCELIQDTLVQGKPGSAFKFRVNGMDIFAKGSNWIPGHVFDKQMTTEKKRFACALYPTNKEFLDNVKLEVSDQVRRLMIHPCIVLWSGNNENQEFMVKGWDEATVRNPYIFAVDYYKLYVETIMSTLQTLDTSRSFISTSPSAGLISTTPYTERYVLRDDERGLYGDVHFYDYKHNGLHVEYYPNSRFVSEYGAQSMCSYSSWKTISSTDDWHPLSKLSVHRNHHGNGQREMLEQIEYQFQLPNNLSKYYHSDPESLSNVPVQQRGNLFDVFCYLTQCVQARSITAQTEHYGQASNMEASRWKPLHYYMKHSFADILVSGYQPAGSRTFNVHISNDRYAAIEGFMIVRSYKIDDNQFETGSSIPFSVDGHSSKYISQVKSDLLGDGSGDNSPRLLFATATVVTGDRLALMNSQWREDHLPGATESLSHSDHGIVWLEWSESKMEGYFEENAFWLLPQEPKRVIYYGWDNDLTITPSQTDAMDWSMTRLPGFILTQLVMDVRGQGLQQPRMPEDSEGPQLMDIADAKAYLTATNYPTYDYKHAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZR2</accession>
    <name>A0A9P6MZR2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ndc10 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006801</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000338">
        <property type="protein sequence ID" value="KAG0018737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZR2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.20">
        <property type="entry name" value="Centromere DNA-binding protein complex CBF3 subunit, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038279">
        <property type="entry name" value="Ndc10_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031872">
        <property type="entry name" value="NDC10_II"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16787">
        <property type="entry name" value="NDC10_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ndc10" evidence="1">
        <location>
            <begin position="53"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0018737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="301" mass="34810" checksum="3D2666BB960EDEA3" modified="2023-09-13" version="1">MKKGWRQLEREYLEHCEEEYGALADLVRPQLVHLLLGAELWSPLPHTSSKSRAEKESIPNFSDANDWHDIKAIRACKNPKGKQTDRTVALVSSIQIDSTKSILRTCRVHCPNITHTGRQSRTSEAYHLRLHHNEMAKLGRWSSGQMEAAHPPELPIHGAFIMAHFKENEGYFLERDLVTPPLPLQRFIFPWIENTFEKDMPERTASWVEECDREMEGIDGESAVKDDYHWSPEESSMARDACSAFSRRAMTDRVRFLRLLVRMRRVILQDAVLYLKPNKDGKILSNIIIESLPHISKSKLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZS8</accession>
    <name>A0A9P6MZS8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NADPH-dependent FMN reductase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006851</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000341">
        <property type="protein sequence ID" value="KAG0018699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZS8"/>
    <dbReference type="OrthoDB" id="68575at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005025">
        <property type="entry name" value="FMN_Rdtase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050712">
        <property type="entry name" value="NAD(P)H-dep_reductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30543">
        <property type="entry name" value="CHROMATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30543:SF21">
        <property type="entry name" value="NAD(P)H-DEPENDENT FMN REDUCTASE LOT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03358">
        <property type="entry name" value="FMN_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADPH-dependent FMN reductase-like" evidence="1">
        <location>
            <begin position="5"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0018699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="209" mass="23249" checksum="ADF14E341672B750" modified="2023-09-13" version="1">MPSQKIALVTCSTRNPRVNPFITNYVHSLLAAVVPEDVSLHILDIAEQSLPLYDEPTIPSLLPPDDPTPHYQHEHTRQWSAKVRGFDAFIFITPQYNWSLPASLKNALDYLFYEWKGKPAAVVSYGGHGGGKAADHLRGVFGGLRMRAAATAPTLTIKGAVITETIEQGRVTEIQAKFWQEAGAEDAIRQMFDEIIQLLREGLDARSQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N019</accession>
    <name>A0A9P6N019_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ion transport domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_006707</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000332">
        <property type="protein sequence ID" value="KAG0018813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005216">
        <property type="term" value="F:monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098703">
        <property type="term" value="P:calcium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024862">
        <property type="entry name" value="TRPV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036930">
        <property type="entry name" value="WGR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10582:SF2">
        <property type="entry name" value="INACTIVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10582">
        <property type="entry name" value="TRANSIENT RECEPTOR POTENTIAL ION CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69322">
        <property type="entry name" value="Tricorn protease domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142921">
        <property type="entry name" value="WGR domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="719"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="1067"/>
            <end position="1089"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="1101"/>
            <end position="1122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="1134"/>
            <end position="1154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="1166"/>
            <end position="1184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="1204"/>
            <end position="1226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="1288"/>
            <end position="1308"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="8">
        <location>
            <begin position="1068"/>
            <end position="1319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="163"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="880"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1029"/>
            <end position="1049"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1422"/>
            <end position="1446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1426"/>
            <end position="1437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0018813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1734" mass="196648" checksum="288BFBE5E7510361" modified="2023-09-13" version="1">MANSSKDAQVRYFATTTDKGIKTEKTNKARTTQSKRIKYFGLKEFPGLDKAPLIPHDCTVFKFEATFEDQKAGHYCISWKLKLQPWFSVPWGFHVQAIVTYKGDPDDRTGSLDVLIPKERIEKLRLNRWQEINIQEQLIIHPHCGNPATVKLVLKNNEPPEKAGKVKKAIKAEKSSKKDGSEEKYGSFLVSNVSIHPFHKCNRNPQDFDCAESFIETITSCADNIPISRISAAPNVNLIATLCVENNMIHVSTWDYSKTQTHPRDSKHSFFDGTPKAVKDIPCEDGISKLPLGISLSPDGKQLAVFQEPKIGDWEAGAAVKEANFKFRLISFDNPDSVIPMDGQMSQPDISIPGSNIPLLQSFMGFAKFLPSTDREQPKNSGKNNDTNNCQSLFAACNGIYLDIFDCSRTKWRHLHSITLTDLSFTLSRRITCQMMVESMGPTIFLWLEGKDTCSTWSVNNGANVSRLSSWEDNVNFADHVHRSNLKIAISPDESIIALSGTDGTIRTFFAKSGIEINSIRFNNSKIEYLGFISQNGYERILVIVQNELTRKSKVRVCDPLDLNIRTKFHIVPIPTAGTTLLLSASCGRLESDNKPMVCAAEGAVLRFYNIQKKYPDPIENRKYPIVERKKKIEVDVESNNKDVTGADSGYRRTVIYELNVFPDTKPLGGVGKRDYWILHVSIFRKTKNSEFDNKELFNFVPEPWLRIPTSRYAPEDLLTIYFLPCNMRFVVIGFQSIQIWALPSRKYSNVTLLAFWSKPKDFQSLLRCSLSHHELSKEFHAISDAFVFHTDTPDTPDWDSTRLKVILLDESEERVILPGRSHSHHGVLPCYHSIHLLAAAYSIASENEAFKLHADALVQFAARHINRVTPFKHVMPKERRIEKSSGSIASDADGTDADGDKGLDMAGPEIEDSEKVGILRLLLNNPSFQRMGNPFLKALLSTGSWIPREEPSTSPIGQAMYVKNKSYVTNNAIVAKPPYQVWKSSDTPWHKYTNPVFRLRTQLPFQASRPKTRVGLLSRSVQPKRIKSFPASPEESKNSDTSSNGPNNSSASGGYTFGMVRWAARFLLVLAFSLLFIAVTVAQIRANAGIGKYLSGWDTIIYTVIGLGGVCLLYEFWKFCLDWRRYVSYPYNYLSLLSFCSSTVGCILSLIAYHGPHNVQGPDQIWWISFAILGVYINILFELKVFQPIGVFVYTLIRISIKIVWFLAIFGLSLVAFTHAFLHILHTRNDSCAILTGDDQTTCEVAQTKYPQNSFQALLTTYFFIAGIYDPLDNDLEPADPDYSLKILLAIFIAFTVILMMNLLIAIMNDGFSESKEEGQLTWLRQWSQVIVEVELFMMSQSQRENRDFFPDYIYYGAIPQDVEEYERKGSAKRPSDGPTDDKVLTDFAKDDSQQRNLLTVRQDVKYLLRNQLRIENLMGKTHPTAETNSRNSIQDATPGVTSGVVGDDKGHPKTFYLYYDDDTYGAVLKEKETDAKYLMELLYSTETKSYYVYYHNGRIDFRLNGPYGTIEDAKRIFQDSYKEKFGVEWIGRKEAKYECWTYDEETYNTIEEAEDVKAAIGETEIKTEIGAVVISSGITKSFKYAVRVFTPHEAHADVSTDTEDSAKKDAAPRAKSGVDGLCPIFKIFRVCYEGEEEYSAALTEKKSGKTCVIQLLRSDEIEAYYVYYRYGETDSHFSGSYKDIDTAKVVFKDVFKKKFDIEWSKRKTAYSEHWKYVYKVHDFEPAVITTSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N097</accession>
    <name>A0A9P6N097_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Kinesin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">KAR3</name>
        <name evidence="15" type="ORF">BGZ80_006316</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-14 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000311">
        <property type="protein sequence ID" value="KAG0019093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N097"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090307">
        <property type="term" value="P:mitotic spindle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01366">
        <property type="entry name" value="KISc_C_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.850.10:FF:000065">
        <property type="entry name" value="Kinesin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47972">
        <property type="entry name" value="KINESIN-LIKE PROTEIN KLP-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47972:SF45">
        <property type="entry name" value="PROTEIN CLARET SEGREGATIONAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4 11" id="KW-0493">Microtubule</keyword>
    <keyword evidence="8 10 11" id="KW-0505">Motor protein</keyword>
    <keyword evidence="5 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="14">
        <location>
            <begin position="480"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="58"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="298"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="411"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="10"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="58"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="80"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="93"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="106"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="132"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="169"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="200"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="211"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="574"/>
            <end position="581"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0019093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="832" mass="90307" checksum="415FEC11A0A0A3E1" modified="2023-09-13" version="1">MEQLNRSISKLKPPTKITSSSTSSSTIATALAVAAALGGNENSAITNNQSNIAKAVTKTAPMPATKTTNGSGPGLGGISAYSNTGTATQGLKRKAEDSTTEKRTRNQLATSKPSSTINALNGVAAKKPVSNPIDSSKPQVQNKAGAGAPARVPLSRVGQRGAASNMTNRAAATSSRTPAAPSVANTKAKAGPAATTTRTQAVLKTRNQQPSLVSSTSSSISESKSATAGTGAGAESSQAAVAELSSAEILNALAISKKKKRPAWDTKGRLEDMEELTSTLHHLLQTSTTNMNDLTSKLESSESKISELETFRQSLESKVAVKESENKDILQKMKHVEQDLQMTARQHEDEIRSLRSQHAMEMEQLRMMQARLKQETEVLETKLRSTNTQLDQQIQENTSLRATISTQSSNCLALESDNRALKMKIERTENTLAQRESTIETLERKLSESQMTVQELEQRIRQEETIRRRLHNTIQELKGNIRVFCRVRPVVRSESASKAELTTALIKYPDQEGREIEFSHTTETATGSQIGKTYPFTFDKVFQESSTQDDVFEEISQLVQSALDGYNVCIFAYGQTGSGKTHTMEGPLNADAKSMGMIPRSVMQIYENAKALESKGWVYTMEGQYVEIYNESINDLLGNDGLESGKKHEIRHGPNGKTTITDITTVVLTSPEKVAALLKRAAHNRSVGSTQMNERSSRSHCVFTLRLSGNNTITEESSEGVLNLIDLAGSERLSQSGATGDRLKETQAINKSLSSLGDVIYAISNKDPHIPYRNSKLTYLLQNSLGGNSKTLMFVNISPLMSNFNETLCSLRFATKVNACTIGTATKRAVKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0B4</accession>
    <name>A0A9P6N0B4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_005980</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000295">
        <property type="protein sequence ID" value="KAG0019325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0B4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000074">
        <property type="entry name" value="Angio-associated migratory cell protein-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051179">
        <property type="entry name" value="WD_repeat_multifunction"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19857:SF8">
        <property type="entry name" value="ANGIO-ASSOCIATED MIGRATORY CELL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19857">
        <property type="entry name" value="MITOCHONDRIAL DIVISION PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="66"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="109"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="160"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="192"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="239"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="281"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="322"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="11"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0019325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="400" mass="43966" checksum="3D6768A3B8054F37" modified="2023-09-13" version="1">MHDESDHEEFLDPDEVDEVQVLEDGQDDMMEEDDDENAEEAEQYDENGNPVDDEMVELEDDSVQGFFTHKEPVYDVALHPVHQNIAVSGGGDDKSYLWRLYDGEQLYEFGGHTDSVTQVAFSVDGTYVASGSMDGKVRVWKSETGEFVCELEGPDEVVWINWHPKGNIILAGATDSSVWMWAVPSGSFMNVFNGHSGPVTSGMFTPDGKRIVTVSEDASLIVWDPKTAAALHRITSEDARFHSDVITCLAINKDSTLAMTGSADGTAKLINLHSGSILGSFENHTDAIETVGFSEHLNLAATGSLDGRLNIWDVQTMHLRTSCEHKGPIIKLQWHKTQPLVTSCSADRSVQVWDGRTGENVKTWLGHQDAVLCFAMTNDGLTCVTGSDDGCSLVFRMVDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0L9</accession>
    <name>A0A9P6N0L9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">NAD-dependent protein deacetylase sirtuin-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">SIRT2_2</name>
        <name evidence="10" type="ORF">BGZ80_005587</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sirtuin family. Class I subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000275">
        <property type="protein sequence ID" value="KAG0019589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0L9"/>
    <dbReference type="OrthoDB" id="420264at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017136">
        <property type="term" value="F:histone deacetylase activity, NAD-dependent"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1600.10">
        <property type="entry name" value="SIR2/SIRT2 'Small Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050134">
        <property type="entry name" value="NAD-dep_sirtuin_deacylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003000">
        <property type="entry name" value="Sirtuin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026591">
        <property type="entry name" value="Sirtuin_cat_small_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085:SF6">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02146">
        <property type="entry name" value="SIR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="9">
        <location>
            <begin position="24"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="306"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="320"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="365"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="377"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="135"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0019589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="408" mass="45125" checksum="439CE292C0AAF337" modified="2023-09-13" version="1" fragment="single">MSAPRASVKSRPTRIQGEAEPRVPVLKDASLESVADFINQGKAKNIIVMSGAGISTAAGIKDFRTPGTGLYDDLKRFNLPYPQAVFDISFFKPTLTHYFLPLLAKKGLLLRSYTQNIDMLERLTGLDPDLLVESHGSFATSKCIKCDTMVDSDIVKKHILKSEIPHCKKCGGLVKPTITFFGEELPPRFGTLAMVDFKKCDLLIVLGTSLQVEPFNRLITRVPESCPRLLINRERAGEDIYGGFDFNGKWKYPNVRDALFLGSCDEGTRKLAKLCGWEDELQAMYEAGNIKMQEAEELEALTLAKEQEEEEKAGTNVKGGSKDTKDTKDTKDTKDTKGAKDAKNAKSAKDVKDTKDSDDLDSLTERFQATNLSSTTEKADAKKDSKETPYKVASKTESKIKNSDPSVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0M1</accession>
    <name>A0A9P6N0M1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="15 16">Tubulin alpha chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">BGZ80_003759</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13 16">Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4 16">Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 16">Belongs to the tubulin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000201">
        <property type="protein sequence ID" value="KAG0020699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0M1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005200">
        <property type="term" value="F:structural constituent of cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02186">
        <property type="entry name" value="alpha_tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.600:FF:000005">
        <property type="entry name" value="Tubulin alpha chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1440:FF:000007">
        <property type="entry name" value="Tubulin alpha chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.600">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="entry name" value="Tubulin/FtsZ, GTPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002452">
        <property type="entry name" value="Alpha_tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000217">
        <property type="entry name" value="Tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023123">
        <property type="entry name" value="Tubulin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017975">
        <property type="entry name" value="Tubulin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11588">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03953">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01162">
        <property type="entry name" value="ALPHATUBULIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01161">
        <property type="entry name" value="TUBULIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="Tubulin C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="Tubulin nucleotide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00227">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="17" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="11 16" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 16" id="KW-0493">Microtubule</keyword>
    <keyword evidence="8 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin/FtsZ GTPase" evidence="18">
        <location>
            <begin position="49"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin/FtsZ 2-layer sandwich" evidence="19">
        <location>
            <begin position="215"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="17">
        <location>
            <begin position="358"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00034296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00071544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU000352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAG0020699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="389" mass="43130" checksum="8181AF904F210192" modified="2023-09-13" version="1">MREVISIHVGQAGVQIGNACWELYCLEHGIEPDGTIASDKKASQFDSSSSTFFSETGAGKHVPRAIFVDLEETVIDEVRRGTYRSLFHPEQMISGKEDAANNYARGHYTIGKELVDTVLERVRKLADACTGLQGFFVFHSFGGGTGSGFGALLLERLSADYGKKSKFEFAVYPAPEMATSVVEPYNSILTTHTTLEHTDCAFMVDNEAIYDICKRNLDVSRPTYTHLNRMIAQVVSSITASLRFVGSLNGKYMACCLLYRGDVIPKDVSAAIAIVKTKKTIQFVDWCPTGFKVGINDQPPTVFPGGEVAKVQRAVCMLSNTTAIGEAWSRLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVASESAEMEQEEEEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N188</accession>
    <name>A0A9P6N188_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Sm protein F</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BGZ80_004673</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000236">
        <property type="protein sequence ID" value="KAG0020168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N188"/>
    <dbReference type="OrthoDB" id="409625at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034715">
        <property type="term" value="C:pICln-Sm protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01722">
        <property type="entry name" value="Sm_F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000011">
        <property type="entry name" value="small nuclear ribonucleoprotein F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016487">
        <property type="entry name" value="Lsm6/sSmF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034100">
        <property type="entry name" value="Sm_F"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11021:SF0">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11021">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN F SNRNP-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006609">
        <property type="entry name" value="snRNP_SmF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 10" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 10" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="11">
        <location>
            <begin position="8"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR006609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0020168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="80" mass="8888" checksum="4F4BCE14B3AA6A27" modified="2023-09-13" version="1">MSTFVPVNPKPFLNDLTGKAVMVKLKWGQEYKGFLVSVDSYMNLQLANTEEFVDGTSAGTLGEVLIRCNNVLYVRGIDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1C7</accession>
    <name>A0A9P6N1C7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cystatin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_004630</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000234">
        <property type="protein sequence ID" value="KAG0020192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1C7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004869">
        <property type="term" value="F:cysteine-type endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00042">
        <property type="entry name" value="CY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000010">
        <property type="entry name" value="Cystatin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046350">
        <property type="entry name" value="Cystatin_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54403">
        <property type="entry name" value="Cystatin/monellin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0020192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="120" mass="13544" checksum="1C1F3ABEAC64E846" modified="2023-09-13" version="1">MTVIDAAHPLSAVDLALDTALTELTPKILESYLKAKHLPASNSHEFEFEPVGFTTQTVAGTNYYVKMLVHDKCHTDKHTREYIHIRIFVQVWTNTIQLTGLSVDKHEGDSLRDPITDIVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1H1</accession>
    <name>A0A9P6N1H1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">3'-phosphate/5'-hydroxy nucleic acid ligase</fullName>
            <ecNumber evidence="1">6.5.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BGZ80_004366</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a 3'-end 3'-phospho-ribonucleotide-RNA + a 5'-end dephospho-ribonucleoside-RNA + GTP = a ribonucleotidyl-ribonucleotide-RNA + GMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:68076"/>
            <dbReference type="Rhea" id="RHEA-COMP:10463"/>
            <dbReference type="Rhea" id="RHEA-COMP:13936"/>
            <dbReference type="Rhea" id="RHEA-COMP:17355"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:83062"/>
            <dbReference type="ChEBI" id="CHEBI:138284"/>
            <dbReference type="ChEBI" id="CHEBI:173118"/>
            <dbReference type="EC" id="6.5.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="10">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.8" evidence="1"/>
    <dbReference type="EMBL" id="JAAAID010000223">
        <property type="protein sequence ID" value="KAG0020352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1H1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003972">
        <property type="term" value="F:RNA ligase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0170057">
        <property type="term" value="F:RNA ligase (GTP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1860.10">
        <property type="entry name" value="tRNA-splicing ligase RtcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001233">
        <property type="entry name" value="RtcB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036025">
        <property type="entry name" value="RtcB-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11118">
        <property type="entry name" value="RNA-SPLICING LIGASE RTCB HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11118:SF1">
        <property type="entry name" value="RNA-SPLICING LIGASE RTCB HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01139">
        <property type="entry name" value="RtcB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103365">
        <property type="entry name" value="Hypothetical protein PH1602"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 10" id="KW-0464">Manganese</keyword>
    <keyword evidence="3 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="96"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="active site" description="GMP-histidine intermediate" evidence="8">
        <location>
            <position position="421"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="272"/>
            <end position="276"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="273"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="304"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="382"/>
            <end position="383"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="382"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="421"/>
            <end position="424"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601233-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR601233-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR601233-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0020352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="507" mass="55685" checksum="45D27011B27C54B2" modified="2023-09-13" version="1">MPSIRLTLVNNAKQTQRSVVILKVEDSDSADPINDILTLAKNKLRLKKAKTLYLNHGVELADASWFASGKVTQDSLIYVSCGEGFVGQTKSEVPSAYSTTTAQSSEPSTTTGQDNDTGKIDADTPVEKLDMDSLSLDPGVSATIAILAKKSYVDPDANSQLNRTAMFPGMRRVVGQPDLHPGNQYPIGATFITQRIIYPALIGNDIGCGMAVYKTRLASNIKPQKIVDKLHHLEGRWTEGDPQEFLISKLGEEHSETGKAHLDQLGTLGGGNHFAEFVVIEKLVDQELCDSFGLVDSKTYLIVHSGSRKFGQTILESSNSMQTKAEKKHLGIDAESEVGKAYLKQHDMACAWAKTNRELIAHRVLTRLNAEEDAEKILDIWHNNVEQKVIESLDPEKPCWIHRKGAAPSDRGLVVIPGSPHGAGRLLPRAKALQKRPQASKQASISALQTTELGSSVICEDTDLLFEEQPGAYKEITDIIEDLEPFVKVVAILRPICTYKMRNEHRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1S1</accession>
    <name>A0A9P6N1S1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_001338</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the REI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000130">
        <property type="protein sequence ID" value="KAG0021961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1S1"/>
    <dbReference type="OrthoDB" id="19329at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003604">
        <property type="entry name" value="Matrin/U1-like-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041661">
        <property type="entry name" value="ZN622/Rei1/Reh1_Znf-C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040025">
        <property type="entry name" value="Znf622/Rei1/Reh1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022755">
        <property type="entry name" value="Znf_C2H2_jaz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13182:SF8">
        <property type="entry name" value="CYTOPLASMIC 60S SUBUNIT BIOGENESIS FACTOR ZNF622"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13182">
        <property type="entry name" value="ZINC FINGER PROTEIN 622"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12756">
        <property type="entry name" value="zf-C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12171">
        <property type="entry name" value="zf-C2H2_jaz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00451">
        <property type="entry name" value="ZnF_U1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="95"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="295"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="295"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="305"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0021961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="440" mass="50266" checksum="5C5206BA00FDE5FA" modified="2023-09-13" version="1">MSKIVAPTSLAQGTILSMPDAPRSSLFTCLACHVAFKSADIQREHYRSDWHRYNLKRKMVELPPVTAEMFTQKVIAQQQQAADDEAAAAVSSNDCKICRKSYSSENAYQNHLVSKKHKETEAKLKANPRPAAAVVEKPTKSDVESITSKVTVDLTITDETTQEELEELMDKKIESAVRLELTDCLFCTEKAETFESNVDHMTKTHGLFIPDIEYLVDIEGLIKYLGEKISIGNVCLYCNGKGRQIRSLEAVRRHMVDKGHCKIPYDTESDMMEISDFYDFRSSYPEEQQRKMLEAAERADRGETGPDDEDLDLDEDSVGTSVRLGEDEMELILPSGARLGHRSLNKYFRQNVKPEESRDSVLINRLLTHYTDHMGYDLALAKTKDRSERGQALVARNEGEARWAHKQTSTFRDFRRVEEFKSRVGQKQNKLQKHYREQIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2A5</accession>
    <name>A0A9P6N2A5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Allantoicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">DAL2_4</name>
        <name evidence="5" type="ORF">BGZ80_011729</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(S)-ureidoglycolate = urea + glyoxylate</text>
            <dbReference type="Rhea" id="RHEA:11304"/>
            <dbReference type="ChEBI" id="CHEBI:16199"/>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
            <dbReference type="ChEBI" id="CHEBI:57296"/>
            <dbReference type="EC" id="4.3.2.3"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000098">
        <property type="protein sequence ID" value="KAG0022583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N2A5"/>
    <dbReference type="OrthoDB" id="10266039at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004848">
        <property type="term" value="F:ureidoglycolate hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050385">
        <property type="term" value="F:ureidoglycolate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000256">
        <property type="term" value="P:allantoin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006144">
        <property type="term" value="P:purine nucleobase metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd20298">
        <property type="entry name" value="cupin_UAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.480">
        <property type="entry name" value="Ureidoglycolate hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047233">
        <property type="entry name" value="UAH_cupin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007247">
        <property type="entry name" value="Ureidogly_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024060">
        <property type="entry name" value="Ureidoglycolate_lyase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21221">
        <property type="entry name" value="UREIDOGLYCOLATE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21221:SF1">
        <property type="entry name" value="UREIDOGLYCOLATE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04115">
        <property type="entry name" value="Ureidogly_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0659">Purine metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0022583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="208" mass="22709" checksum="680902A1E3F5F898" modified="2023-09-13" version="1">MSPSIPEETVKALLTVQPVAITNENFAQWGQVVRMPDADPNAVQVNQGSAQKYSHLAEITNLRPAATDSANPNPTLTSATTNVAIFKCYKPVTTPQFAIKLLERHPYSSQMFMPMGGDGNGSYVVVTAENGPDDKPVLSTLRAFKCNNTLGINYKPNIWHHPMIVVEKPVQFMTITHESGVPMEDCEEYWFTKESGSEGGAAALIQLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N373</accession>
    <name>A0A9P6N373_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_001604</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000137">
        <property type="protein sequence ID" value="KAG0021830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2503993at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902929">
        <property type="term" value="C:plasma membrane of growing cell tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00174">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024982">
        <property type="entry name" value="Rax2-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048266">
        <property type="entry name" value="Rax2-like_second"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048265">
        <property type="entry name" value="Rax2-like_third"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31778">
        <property type="entry name" value="BUD SITE SELECTION PROTEIN RAX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31778:SF2">
        <property type="entry name" value="BUD SITE SELECTION PROTEIN RAX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12768">
        <property type="entry name" value="Rax2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20842">
        <property type="entry name" value="Rax2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20843">
        <property type="entry name" value="Rax2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14604">
        <property type="entry name" value="SH3_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="1507"/>
            <end position="1535"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="5">
        <location>
            <begin position="1772"/>
            <end position="1835"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="207"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1302"/>
            <end position="1367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1459"/>
            <end position="1478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1545"/>
            <end position="1579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1599"/>
            <end position="1626"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1645"/>
            <end position="1731"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="217"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1330"/>
            <end position="1344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1345"/>
            <end position="1357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1358"/>
            <end position="1367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1462"/>
            <end position="1478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1605"/>
            <end position="1615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1645"/>
            <end position="1654"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1697"/>
            <end position="1716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1721"/>
            <end position="1731"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0021830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1835" mass="194324" checksum="168C4FE191F88806" modified="2023-09-13" version="1">MVSPPVDFATLGQMAVLGDFDALTPIVASGQQNTFDSNTFSILELTKVPLRPGTGVSHNRNSSSQEDDAILSTPVLLASFSIDNSTTGASSQSNGITATCVLDHAPHQVYIGGYFKQSLSVTAQSINGSCTDATTGINYIGLYDSKLKRFLSMGNGLDGPVEALVCDSSTDQVYVAGKFRAPLQEMPSGGNSSNNSRYQTQGSFGGGVAVWKRNPQHDTNSNASTGTNGVATQAAGTWIPLPFKGLNGVVTSVAKASDGTLYFGGQFDTTADGESFSAPDTQLVNMDNVVVTTGNGEDPLQDRNIICQPSVVTQRNWIMPDNIPGYWRAEFPLLITPTLFRLWNVDTTEEGSGGAAANRGAKTFSIMAQPSNQLLNLSYIDPDTQLVQYCTTCTLLPWSALTSVQQNHQDFLVVTPVLLHGVQIDIKSWYGQGGGLGGIEVYQSEIFVRAVDALNSASTCSSPATMNATYNNDNKDLRASSSFLGADWATMNMIDGWQTVMAANVSATNEKMRKQAYVDLVPYLQEPGMYDVYLYTPACTSKAQPDTASSEDNSTRALPSNSCSDRGFVDVNMYFASPENVMTVTLSQTNNVDKYDKIYSGMIAHSTSDFRPHVVVGPSVHKTGTSGGGNTQSVIVDSIQFVKQATLNDTNSLLFYRPGSGSVAAGNAGKQKKDQVRGLDSSVWGTLPTQLPSAATVNSLVSYYGITGSSSLTSSLLFIGGSFTGTGYANLVAWDATAFVPMAPVSPSASGLDGVVYSMALYQSTLYVAGDFQQAYGAGVGGSQLGGLAMYDIQSKEWASFGNVTQNFLSGAQFQSIQLSTSAEGLPRLILEGKFMWAQGVGSSSVSVAVWDINNQKWIREDLQATSNGGTSGKGEIPFGYVHGQISYLNRVLGSNSNVSASNAVPVVLIAGTIDSLDSYKVHQPENMAWVTSAGALKTVNLSPTISMAPISGSGDTTSDATAASEPIIGQVPEMPKASAGIMYFNKDAQQWITIVGGANANGTIAAGYFNTPEVPSPSQDSMLTYKDLNLAPAAASAIKGEILSLGISKDEATGYASSDSADELLLIGGAFKSSGSLSVNGLALYDLAAGQVVSSSMVPTLQGVQGRNPVVHVIKSRPGNARKMLVLAGDFSGIGSDVSCELVCLWEPAEARRAIDNKESIEGSFKSIYGDSGSSSKKHLGTLKGVVNDITFEDDKNMFVAGDLIVNGVPCGVASFNFDNYKWTTFGSMMDTTSGSNQSLSADTLTGPVTAIAHDSMFHRFFIAGRSSADGSAYFRKWDGTRFIRVSPDFMPTSDVHQLEILPASKNAPDRTAATSSSFTNDSSDKSNGDNTSGAGNNISNKNSSPSATSTSSATPQESITSMGVDPNDTTYILEQGYILLVSGRIVLGTASPSSYSNQESSLAFFDGQSWFPYLQSSRNASSSASSSSASTNLALASPLLSARHAIGLDLMERATPVGDSTPTSSSSPSAVATATSPSRVRDQGVFRALAIAHLPRIIARDYLSLPYIILISVAISLGLILLIVLFGFLFVWLERRLSKEERATRPKLGSSIMENGHDGRAHKSGSRGRGATNGRVSPNEPYFVGSLGVTQGALFITNTNPSKNEKGSSHREASASNGKPVYQPNSTIAQATDALVTQFVRSHQLQLTSAQNPPEDRTKERSVPPSPDRRSKKSHHSIHYQQSPPPEGRGSSSSDLVNPLSQQRFSTLLTTSYDPNMPITPTSREPTSPTTIMTTPGGVIDNINAGADAEMLVGVVNATPIRDSMGGAGTGGVFYYAKFPFRAREIGELGFRAGERILVVDMSDDIWWMGVIQEPNGQQIHGVFPSNYVGPKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3E8</accession>
    <name>A0A9P6N3E8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">THUMP domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">THUMPD1</name>
        <name evidence="4" type="ORF">BGZ80_008097</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000043">
        <property type="protein sequence ID" value="KAG0023770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3E8"/>
    <dbReference type="OrthoDB" id="367221at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11717">
        <property type="entry name" value="THUMP_THUMPD1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2300.10:FF:000001">
        <property type="entry name" value="THUMP domain-containing protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2300.10">
        <property type="entry name" value="THUMP superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004114">
        <property type="entry name" value="THUMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040183">
        <property type="entry name" value="THUMPD1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13452">
        <property type="entry name" value="THUMP DOMAIN CONTAINING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13452:SF10">
        <property type="entry name" value="THUMP DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02926">
        <property type="entry name" value="THUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00981">
        <property type="entry name" value="THUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143437">
        <property type="entry name" value="THUMP domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51165">
        <property type="entry name" value="THUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="THUMP" evidence="3">
        <location>
            <begin position="139"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="267"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="10"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="267"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0023770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="287" mass="32039" checksum="E8BBBE53BD0692B2" modified="2023-09-13" version="1">MGGNKRKAGKAQEAKDGKKAKTDVHKIGKYLPGGFPIDPKMKGVMVTCARGKEAQAGREACDLLSEYAEKLYGSESVADEPEGDEDESIEDAIAREVAQAKKTKGGKKFLPLMTGTDCVIFIRAMDIEPSSLCHHVLTDLQKSGSKRTRYCQRFIPVDETSYANMDDITVMSERVLKPYFHAENQQPTTFKVIPKIRHNDKVDREVLVKMLASAAGRNQKHSVNLNEPNYVILAEVIKSICFLSVVKDYDSLKKYNIQSIFEAAQKEGKEELKDTSKEDNETVTNNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3F7</accession>
    <name>A0A9P6N3F7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_007845</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ANT/ATPSC lysine N-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000041">
        <property type="protein sequence ID" value="KAG0023823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3F7"/>
    <dbReference type="OrthoDB" id="66144at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905706">
        <property type="term" value="P:regulation of mitochondrial ATP synthesis coupled proton transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026170">
        <property type="entry name" value="FAM173A/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13610">
        <property type="entry name" value="METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13610:SF11">
        <property type="entry name" value="METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="6">
        <location>
            <begin position="84"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0023823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="219" mass="24682" checksum="47139A939224F227" modified="2023-09-13" version="1">MTPSISPLDPPNSDSKATIPKSDDGALTSFDPKKLEYFHTQYPDYIAEEVDLPLWIDGVDTTYAPFIPTSTRRVLLALEMAHLTSEDKVLDVGSGDGRFCYAAVTFFGAQKAMGIECEQDLIEKSTELAQDLVDQGRISFERADLTNWRESSTMKSKEWSVIVVFLSPEGGDDMEEWLVQEFERGVRIVALVFDLKQLKGLHCSVEDSQEGIWIYEKQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N409</accession>
    <name>A0A9P6N409_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein uL5m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_010512</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000074">
        <property type="protein sequence ID" value="KAG0023051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N409"/>
    <dbReference type="OrthoDB" id="539541at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1440.10:FF:000001">
        <property type="entry name" value="50S ribosomal protein L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002132">
        <property type="entry name" value="Ribosomal_uL5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031309">
        <property type="entry name" value="Ribosomal_uL5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022803">
        <property type="entry name" value="Ribosomal_uL5_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031310">
        <property type="entry name" value="Ribosomal_uL5_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11994">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00281">
        <property type="entry name" value="Ribosomal_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00673">
        <property type="entry name" value="Ribosomal_L5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55282">
        <property type="entry name" value="RL5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL5 N-terminal" evidence="6">
        <location>
            <begin position="133"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL5 C-terminal" evidence="7">
        <location>
            <begin position="192"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="39"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="292"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="53"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="296"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00040368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0023051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="312" mass="34913" checksum="60C512874A7B5737" modified="2023-09-13" version="1">MTFRIKPISVRTLNLGLLPQTSPIYQAIPAIHLRAKSTISNPRSSDLKKKNTSRNIDSNNDGSASETRILPQAPIYTTGLSRLREHYATSIQEDIMIAAYRHHHKKKRHIPEGVKVELKGKRHLKPSPPPSSPTEIPELVKIDVHCMMKEAITSKYNLLSGIMAIQSITGETPEIIFAKKGVHSWKLRKGMPIGCRVTLKGDKMYQFLDKLVEVVLPKMKEWPGLPEGSGDGTGNIGMGFPPSALSLFPEIESNFDMYPRMTGFDITFNTTAFTNMDARLLMSGFNMPFQKPSAVTRKETTPVKPEEESEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4C6</accession>
    <name>A0A9P6N4C6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_011333</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000009">
        <property type="protein sequence ID" value="KAG0024665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N4C6"/>
    <dbReference type="OrthoDB" id="2448739at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="252"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="191"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="226"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0024665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="508" mass="54755" checksum="D28133ABFE658ABE" modified="2023-09-13" version="1">MTNTLKHRLAQALTLSTHTNSIIVIFSCLSWITPIVRADLTCQSPTGSYNLGDTVTLLWSDNGQYPQVGDVYSASASVYCSSNTALLLQLGSVVNGQPWIIPNNILTSCPGNQIYIEYSGEMYNLLHLLHITTYKLDCRDVYLPSPTTTSISTTTLPSPTQQQTSSTLNPPSTTTTAPIVVTSISIVSIVPTSSGSTQQQQQPSGAGSGSGSGSGPGRGSAEPGSNASPTQSSSPNQPGSNTTTNEPGPNTLVAVLGALAGVLLVALIIVGMIMARKRMTKKRLLADGRIGKAGFAGAAGAVGREGRNGDSEGPWDQIEYHPGGFAEGLEFVPLQHQSEMRDYIRHSHASSQPSSIMNMPMRPVSGYRGDFGYSNRRNFVRNQSYISQAPTLKYLDEYGHEQDVHSVAHFPSEDRHGEPVFATSQPTNQEYHDRIRSTESDEISPYPIFPIPSVNSTRQHSGLIDTGTILEESDPPFEMIQVHPSSLPLHAPVDQLDEHDQEGELHEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-06-18" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4H4</accession>
    <name>A0A9P6N4H4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Multidrug resistance protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">ABCB1_2</name>
        <name evidence="16" type="ORF">BGZ80_006068</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000003">
        <property type="protein sequence ID" value="KAG0024795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015421">
        <property type="term" value="F:ABC-type oligopeptide transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090374">
        <property type="term" value="P:oligopeptide export from mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18577">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18578">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03249">
        <property type="entry name" value="ABC_MTABC3_MDL1_MDL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000916">
        <property type="entry name" value="ABC transporter B family member 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000018">
        <property type="entry name" value="ATP-binding cassette subfamily B member 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000479">
        <property type="entry name" value="Multidrug resistance protein 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394:SF27">
        <property type="entry name" value="ATP-DEPENDENT TRANSLOCASE ABCB1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="99"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="144"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="222"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="246"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="328"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="363"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="774"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="804"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="882"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="909"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="985"/>
            <end position="1003"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1023"/>
            <end position="1042"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="15">
        <location>
            <begin position="103"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="14">
        <location>
            <begin position="424"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="15">
        <location>
            <begin position="774"/>
            <end position="1050"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="14">
        <location>
            <begin position="1084"/>
            <end position="1289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="11"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="48"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="65"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0024795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1297" mass="141593" checksum="A7BEAD126D7A82B8" modified="2023-09-13" version="1">MATATSSQPGRGEKEEFLESEKTHSPEESFMVDIDHNDITATPSSDDLTEKKGKDKGKGKNKGKGKGEGKGKSVDGDDEKPESQVSYLHLYRFASTWDWTCVFIGTLCAFACGVGQPLVALLMGDVINKLNVPNPLDPVNDIRIIVIKFTIVGGAMFIFAYGQMCLFTLSAENQTKRIREKYLHAILRQDISWHDVGKKSESLNSRLSADTQLIFDGLADKVGLCLSSFATFVAGFIIAFTHGWRMSLVLLTSVPLMAAAGAFMSKFATDTSADGQDAYAKAGGVAEQAISSIRTVVAFDGQKRELQKFSDFLDEAYKSGIKKAFGTGAGMGSFMLIMFLSYSLAFFYGAKQVKDGKMNPGDVLTVLFGTVIGAFSIGNVGPNVAVFGKAQAAAFTIFQTIDRVPEIDAFDPSGLKPENLTGHIVVKDVNFSYPSRPDIQILKNMNIEVKPGQTVALVGHSGSGKSTIIGLLERFYNPSSGSITLDGIELKDINVRHLRDSIGLVSQEPVLFNATIKQNIMYGTRKDQKTPTDKEIEDACRLSNAHDFISKLPQGYNTMVGEKGALLSGGQKQRIAIARALIKNPAILLLDEATSALDTESERIVQAALDNASNGRSTVVIAHRLSTIMNADRIYVMDRGVVLESGTHVSLMAQGGIYTEFVAKQQLKTGGVDVEAPEEVENDIVRTSSPRIAIEETAIPEVARSGRITSTFLRRISSQHSVTRSEKSADGAVALNIPEDKEMTLAREKKEAARKLKMQKAPIGRTMKYLKDDIFLCLLGIFFAMIQGALFQELGDDFIPKANHYALLFFILAFVGFTGFCGGLTVFLSVGERVTRRMRYLSYKSILSQEMAFFDRPENSTGALASRLATDSQQMFDMVSQVILTTVSSIATMSVGLGFAFAASWQMTLIILAAVPVIGLGQYLELASLSGFGEKTRKAYEKSGQVAGEAIANIRTVVSLAKEDTFESRYFEVTREPHKYALNKALFASFGFAMSQGVAYWSYSIGFYGGYRLVEAGIITWGQMFNCMFSIVFTAMSLGHITSELPKFAKGKQSAINVYELLDKDTTIDADRDGIKVDAVHGSLALEKVDFTYPTRQNIQIFNGVDIHVRPSQTVALVGPSGCGKSTIIALLERWYDADGGKVVIDSHDIRDLQLHNIRNHMALVGQEPVLFDMSIKDNILYGLPNGEGTMEQVEEAAKVANIHNFVLSLPNGYDTNVGDKGSQLSGGQKQRIAIARALIRNPKILLLDEATSALDSESEKLVQEALDKARYGRTTIVIEHSPGRRLDLGCQERCHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N6E3</accession>
    <name>A0A9P6N6E3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">CCT-theta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">CCT8</name>
        <name evidence="11" type="ORF">BGZ80_004291</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Molecular chaperone; assists the folding of proteins upon ATP hydrolysis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the T-complex protein 1 (TCP1) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000022">
        <property type="protein sequence ID" value="KAG0024329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N6E3"/>
    <dbReference type="OrthoDB" id="1748577at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005832">
        <property type="term" value="C:chaperonin-containing T-complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03341">
        <property type="entry name" value="TCP1_theta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000008">
        <property type="entry name" value="T-complex protein 1 subunit theta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012721">
        <property type="entry name" value="Chap_CCT_theta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002194">
        <property type="entry name" value="Chaperonin_TCP-1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02346">
        <property type="entry name" value="chap_CCT_theta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00750">
        <property type="entry name" value="TCP1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00751">
        <property type="entry name" value="TCP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0024329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="544" mass="59095" checksum="BAB31B41142435AF" modified="2023-09-13" version="1">MALRIPQGTQMLKDGYKHLQGIDEAVLRNITAVHDLSEITRTSFGPNGRNKIIINHMEKLFVTNDAATIIRELEVVHPAAKLLVMASQQQEAEMGDASNLVSIITGELLQKAEHLLRMGLHPSDIIQGYEVAEAKALEILEELSVEEIKNVQTKDDLFKAVRSSIAAKQYGNEDMLTDLVCEAAIAVMPKDASNFNVDNVRVVKIMGSSLYESRVVKGMVFGRSPEGVITNAKKAKVAIFTCPLDVAQTETKGTVLIHNANEMLDFTKGEEKHMENMLKGIADAGVKVVVTGNAVGELALHYLNRFGIMVVKVLSKFDLRRLCRVTGATALARVGAPMAEEMGFCDVVESVEIGGDRVTVFRQEEEISKTATIVIRGATQNHLDDVERALDDGINVIKALVKDPRLVPGAGASEMELLKRLLAVGEKTPGLNQHSIKKFAEAFEVIPRTLAENAGMDATEVLSKLYASHHADDSGVMGVDIESENNGLLDAHGAGIYDVLSAKGHAIRLATETAMTVLRVDQLIMSKAAGGPVAPKQKQHWDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N6S1</accession>
    <name>A0A9P6N6S1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_004021</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000021">
        <property type="protein sequence ID" value="KAG0024355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N6S1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0024355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="339" mass="37735" checksum="979A95CBA55165BF" modified="2023-09-13" version="1">MGVRGSFIVVRDKGLTPEMHNRAVLPATATQENKIRVDVSQVWFFTYRYAYSKYPLDLGDAHTRLATRLLQLGAKEELFLLFGNLLSASLYLRLCMLGSVPVEVDKSLSEATFTANHVAPLLNASLKADGDAAFQPLPRGPLHLVMLTVETLAPTPATSFSALAIAQLFAGDEETLDGKHKESVCEELYYKESERNVRNKNEREQMDDFTISEKMGQEKSELMLCVTPLYHPPVPPDTESEPEMARNPKLEKRRLDQHEGLLWGPPNKLHGESEGDIVLIPLSQIESTVVTPFRRRYIASTSATASASSPLSQLEPLNFRAALFRTGAAFFTTRFPLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N790</accession>
    <name>A0A9P6N790_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AP-3 complex subunit delta</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Adaptor-related protein complex 3 subunit delta</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Delta-adaptin 3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">APL5</name>
        <name evidence="12" type="ORF">BGZ80_000889</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle</location>
            <location evidence="1">Clathrin-coated vesicle membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the adaptor complexes large subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000012">
        <property type="protein sequence ID" value="KAG0024588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N790"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030123">
        <property type="term" value="C:AP-3 adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030665">
        <property type="term" value="C:clathrin-coated vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006896">
        <property type="term" value="P:Golgi to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000251">
        <property type="entry name" value="AP-3 complex subunit delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017105">
        <property type="entry name" value="AP3_complex_dsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010474">
        <property type="entry name" value="AP3D_dom_metazoa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058898">
        <property type="entry name" value="Mu_AP3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22781:SF12">
        <property type="entry name" value="AP-3 COMPLEX SUBUNIT DELTA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22781">
        <property type="entry name" value="DELTA ADAPTIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26171">
        <property type="entry name" value="Mu_AP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01354">
        <property type="entry name" value="BLVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AP-3 complex subunit delta" evidence="11">
        <location>
            <begin position="717"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="666"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="851"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="948"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="668"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="709"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="779"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="866"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="905"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="968"/>
            <end position="979"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00076742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00083145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0024588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1255" mass="139372" checksum="9F7DCE6B65A76452" modified="2023-09-13" version="1">MNINGLFAHTLTDLIRGIRQNKKNEQGYIAKEIADIRQELRRNDPDLKAQAIAKLTYLQMMGYDMSWASFHVVEVMSSPKFLYKGIGYLGAVQSFTQETDVLMLTTNLIKKDLASSNASEIGVAINGLSHILTPDLARDLCADLVAMLNHSRPIVRKKVLLVLYKVFLKYPEGLRLSFSRMKDRLEDPDPSVVSAAVNVICELARRNPKNYLSLAPQLFKLLTTSSNNWMLIKIIKLFAALTPYEPRLTKKLLPPITSLIQTTPAMSLLYECIHTVIAGGMLATTGSGSNAESANNLAATCVAKLRTFLEDPDQNLKYIGLLALTKILPTHPHLVGEHKDIILKCIDDPDISIRMRTLDLIVGMANKKNLTEIVKRLISHLLPAVESEHAPINNGSAMTALMDPTYRADIIRRIVFICSQNSYANIGNFEWYLAVLSDLTNVAGVNVGNMLMQQFMDVGVRVKSVRSYTVQLMMRLLADTRLTEPENPENANSMVLLAAAWLTSEYCSLLESPENALELLSQRSTAKLDPAIQATYLQSMLKIFAYWMNSLQYSWNEESRQSLSETTDLLREGVKEMFAHSPDLEVQERASNVSVILDIIAEHVPRTPLKIENSISFAPTMPKPPSILGSLYPLFFNQELNPVAPKAQKKVPVPEGLDLETWIHEPIPEPEPESSEDDDFLNENNSSYGYGWSGEGDVTGKSKKKGKKGRDQEDSKESAESKAKRKAERRERQKHDPYYIGGNESPKSQKKGQDDLDVDSIPIVQLNMDGFEKPIVIGKKSKSKKKSKRRERSRSPPIVPVEFAVEEMPEDATLSASDDEIQKAFNAKYAGVSKGILDQDASALHSVDLSIPVGEDEQLPRAKPYMKPEEVRQYEDELAQRRRLEAMQAKKDKKDKKESKKSKSSKKDSADVEEKKKKKKSKSKEEPLIIMDAPVAIKSPEPVVEPVVEAPVKSKSKAKKDSGTSGTKSKKGTSTKKSPKAPVIVEFPDRSDIDLVLNEDVALTYDIALAQSSIEAPTTPGSEPTNDPAVSIKFRVHNRNLTQPISSVRVVLADSFDIRLGGSHAGQDSVTISSSIEPQSRVDAALEVLILGRIRYELRVLGTLFFELNGREESLEFNFAVPPSTFMLAIPRLTGADFSKILTERLALFSATSSATVRLSTGTTGQDEQFWDAVEKITKEVTHTHVVEVVDGAASFFGQSWQGYQVAGLIKVRKGDKQTDEEGGDGFKTIEVEMKCTDQLFVDGLAQEILAVDVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SR51</accession>
    <name>A0A9P6SR51_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008665</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004779">
        <property type="protein sequence ID" value="KAF9992184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SR51"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9992184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="193" mass="21975" checksum="00048FB4F5C56876" modified="2023-09-13" version="1" fragment="single">AARDAQSKPEEETMVMNPFATIDKPDAALNHQYRPRFSPKVRFEPPEEQPAPNILMQYELKSWKEPPEKPTLPTPAKKKPTPIKAEIGDDSRFEHKQILDALSFEHPTVTLNVDRLSKNVRTAVKNELDRLPSSNYTVSNSDFIAEAIVDCIRGAVKVAWETKLYCQQLIGLYLEDLFYPRPTSDESRVVVPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SS90</accession>
    <name>A0A9P6SS90_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007292</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003707">
        <property type="protein sequence ID" value="KAF9996278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SS90"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9996278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="136" mass="14999" checksum="6676323B19D95C12" modified="2023-09-13" version="1" fragment="single">KLVNTTRQDQDAKVPQNKAEAELQRQEDEMLAMTRLLKRVDKKDALTVAKKILENTTTTTTLEETSESITDTTEATNGDVPTSNGTSSNPNETSDRSSNNSQEPRQSRTSNRLRQEIATNVTPSPVHGNKYAARGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SSM0</accession>
    <name>A0A9P6SSM0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RNI-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007267</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003697">
        <property type="protein sequence ID" value="KAF9996338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SSM0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052394">
        <property type="entry name" value="LRR-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24114:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24114">
        <property type="entry name" value="LEUCINE RICH REPEAT FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040291894" description="RNI-like protein" evidence="1">
        <location>
            <begin position="16"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9996338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="332" mass="34845" checksum="B94BB25C663F6681" modified="2023-09-13" version="1" fragment="single">MLVMLFIFMTKMVQTHPLDLHEIRSIIASSLGLKDLASCARVSQDWNDSFTPSLYNSVVLSKQGPSMESIERNKHLIQRLSIQIYAHEKLSSTSARDSVLSIVMANSNLVILDLYNNSIGPNGAVALSEALETNSTLTTLVLSNNSIGPNGAAALSEALKINSTLTTLGLEGNSIGDNGAVALSEALKTNSTLTTLKSSHNSIGDNGAVALSEALKINSTLTTLHLYENSIGDNGAQALSEALKTNSTLTTLCLEVNAIGDSGAQALSEALKTNSTLTTLDLDGNSIGDDGAVALFEALKTNSTLLTLNLGIDSIGNSGDQALSELYKTNMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SU20</accession>
    <name>A0A9P6SU20_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_005960</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002939">
        <property type="protein sequence ID" value="KAG0002522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SU20"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0002522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="121" mass="13377" checksum="A6F0FD60CAC3F0E3" modified="2023-09-13" version="1" fragment="single">YFNSFSDSEELEKKNSIGTYENSGWPSYFDADGDGFPDEWNVRYTLAAGTAGFPTHREDFQISVNGVNVPAVPKSNSHHHYQEYVAAPDNAPHGILKTGTLGDNTEIFHKISELLGLGEQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SVP0</accession>
    <name>A0A9P6SVP0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DNA-binding transcription repressor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ASH1</name>
        <name evidence="4" type="ORF">BGZ80_004803</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002407">
        <property type="protein sequence ID" value="KAG0007327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SVP0"/>
    <dbReference type="OrthoDB" id="2162994at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GATA-type" evidence="3">
        <location>
            <begin position="1043"/>
            <end position="1079"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="173"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="252"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="462"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="567"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="693"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="893"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="938"/>
            <end position="1008"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1024"/>
            <end position="1043"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="26"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="60"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="276"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="306"/>
            <end position="315"/>
        </location>
    </feature>
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        <location>
            <begin position="337"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="357"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="462"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="693"/>
            <end position="702"/>
        </location>
    </feature>
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        <location>
            <begin position="730"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="760"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="821"/>
            <end position="842"/>
        </location>
    </feature>
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        <location>
            <begin position="893"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="942"/>
            <end position="958"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="974"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="985"/>
            <end position="999"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0007327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1130" mass="122336" checksum="A2CFDA9F2E0F4679" modified="2023-09-13" version="1">MTSSVSARQSSIPGHHSGPSKRMRFSLSSLQSPSSNGTAHLTQRDIEALQRKGLLLPTVASTSQSTSNNSKSQASSSTHTSASDSSRSDTPPPKTPTTADQILCTKPPLPIAARVAPLTASLKSKHAKTSSKHKGAKGDENLIIHYKERQLPAYHHGVIEDTCSHLHPGTNIRRHSDSSSSLVLTSPITRNPIPEDTMALDSFRRASIATASPVIPSPLGGRTILYKASYAHTLLSLPSKTVYTGVDQDGEHFNGAGPTPEMTNFKFPAEENRSKTPTSPAMPPSTAAMSPTIRSKRKSSIPMRSPTWNDTQDTSPGVVFRLPFGTPPLPSAPFRKATTPSAHPSSSPMNSLEEESNTSGSTPPTSYPSPASSSRAASASGPSNSEAQESQSIRFETPPSPANRSGLGIQVQESFSEPDATHPLESSALISAAIASTQSQPITFREEDSSISIGDIIVAEQASAAQRQATRSAGQFGAAEDNSMELGSMPTPPLTSRVLSMRVMETSSERQYSPRVGQSEGSNLTSPPTPFTPGPGFSSSQAGHKSHDSSNSLSQIPLEILRMRLESQESAQENKPIDNAMDLDQDQEQDRGSRAGSSSPAKDVEHDKDEEDEDPSILPLWAQRQNHIRRQSLIPRLELDFVKGSGILPPANRGLITPGGAKILSYPVLISDMVHVALDELQAKGVTLDGSDISEESEEDAEQNIHHSSAKGTAKINQRAFRSANNAKATHSKRKKGGASAGKRRGSTVGTKSHAHSQGDEEYQSGEEYTEDLEGANEHNERQGYMTSQFNKRRRVSSVKQNGLDAETSDRHSHRARGTNPADNSVSPSTSPHMGTSSSFRSGNGLGSPVVLGRSYVYENDMEDEEDMGMGMDEAEGVVDIEDDEDVNNHYRRHSEHHQRQNHKGQHKDARRSHVPEHLRIPASELDIAVQLTKEMIESSKKRPHKKEKSKAHNHQHNSRPSLKTLKPLLEATMKVDGRRHGTNDDDDNDNDNDGDERDMDEKEMGKAVGNVQLSSSTKKAAKMAMDQNGSMPKKTPKPKEGKMTTKRCEACGASETPCWRPGYTAHSALCNSCGLRYKKSNVFCAKVGCKYIPLKTEYAAMEADRLKAGRTHLLCHKCKGPVALPIPKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SW01</accession>
    <name>A0A9P6SW01_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_005006</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002498">
        <property type="protein sequence ID" value="KAG0007139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SW01"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050769">
        <property type="entry name" value="NAT_camello-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13947">
        <property type="entry name" value="GNAT FAMILY N-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13947:SF37">
        <property type="entry name" value="LD18367P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="3">
        <location>
            <begin position="110"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="113"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="113"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="123"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="133"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0007139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="263" mass="29151" checksum="22FC5F2A7530674B" modified="2023-09-13" version="1">MSSSLKLQSLNSKNRPGVAQLLFDTHMRSVPGTFNLLKLRPVALILWTAIATAILKFRKTSLQDYHEVLTVLAGSVLVAHGVLFMSILYDASTQAPGPDVVGKLELFVDQDQPTSKTTSSDVNVREVKKRSTESSTSSSSSSSSSSSRDNKFLVLEKDGEPIGCIGAVIDRSRGEARLVSWAIKEKHQRHGSGTLLLKVMMDELKESDIKIQNVRVFLQGSQVPALRLYHKFGFKQIDRTPEWLGERVVLEISLKDWVKNSAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SW26</accession>
    <name>A0A9P6SW26_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">NADH:flavin oxidoreductase/NADH oxidase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_004172</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002155">
        <property type="protein sequence ID" value="KAG0007836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SW26"/>
    <dbReference type="OrthoDB" id="1663137at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003959">
        <property type="term" value="F:NADPH dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044152">
        <property type="entry name" value="YqjM-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43303">
        <property type="entry name" value="NADPH DEHYDROGENASE C23G7.10C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43303:SF4">
        <property type="entry name" value="NADPH DEHYDROGENASE C23G7.10C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0288">FMN</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:flavin oxidoreductase/NADH oxidase N-terminal" evidence="7">
        <location>
            <begin position="39"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0007836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="171" mass="18774" checksum="70125338E49C97BD" modified="2023-09-13" version="1">MLDARSSPRLHTRSTPNQSSGATMLWDHLEAGPYSGIVDSNYVIPREFAIDEFQKIVNAFGSAATRASHTGLNMIETHGARGYLILQSLSPVSNKRADRYDGSLENQTLLLIEIIHEVRSNFSAEKSIFVHISASDNLEYLNDRSSSYEIGICDTGVDVPRDVTLGDSSAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SW43</accession>
    <name>A0A9P6SW43_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DDE-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_004347</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002225">
        <property type="protein sequence ID" value="KAG0007697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SW43"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004875">
        <property type="entry name" value="DDE_SF_endonuclease_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03184">
        <property type="entry name" value="DDE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE-1" evidence="2">
        <location>
            <begin position="170"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0007697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="382" mass="42835" checksum="B7FAE5ADDF052BDC" modified="2023-09-13" version="1">MAKAKRKADADTSTLPLNKQQKLEDASNESIQADSSETAKKGYSLPGSNDLVDFVDTSVNSVKNQRLKDAAAGRLPTHEIIAMLNNYEPNDIYGCDEARFDLKIGPNNERKAGPKYGNRIIQESKIAILLCCNATGSDKRKLFVLSKHIPKGVTEETLRNIEVNTNEDDMQEQGRKIALIFTNLLKYIPLEQEGLSNIAVIRLPNPETFKAHPMCVGVAKAFRVLYAQQMLEAMHRSGEIPNQSVSSASRVKNRTLWSYLAPTWDNVSLPSIRYCFSRSSVMPKRNKKFLNALETESTRPINDLKTELIKKYGGKNGDPSNPRNPTVDHYFISIDAKISSSIFLSELGDMTAFIEKYFGNVKMRQESDFIDEDEIDSDDGQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWI3</accession>
    <name>A0A9P6SWI3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Lysine-specific histone demethylase 1A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">KDM1A</name>
        <name evidence="4" type="ORF">BGZ80_003383</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the flavin monoamine oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001890">
        <property type="protein sequence ID" value="KAG0008493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWI3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.660.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050281">
        <property type="entry name" value="Flavin_monoamine_oxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10742">
        <property type="entry name" value="FLAVIN MONOAMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10742:SF386">
        <property type="entry name" value="LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amine oxidase" evidence="3">
        <location>
            <begin position="17"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="Amine oxidase" evidence="3">
        <location>
            <begin position="160"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0008493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="202" mass="22162" checksum="C15B40AFCAD7773E" modified="2023-09-13" version="1" fragment="single">ALTAYMHDMANYSSFMPVYDKPILVGYATNHAAELMERLSDSEARIVYLCHLAHYFDALVKDNSPEEGEALWAKVSFMTRWNQDPFTRGSYTSIPVGASPADIEEFQIPVSARVYGQLTGDDDYEHCSNDDGDDDDDDVVGNKSVGLSAAVALMSVNDPETGRVFFAGEHTSLGHFASVQGAILSGRLEASKILGREHSHEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXC5</accession>
    <name>A0A9P6SXC5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Aminopeptidase P N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_002043</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the peptidase M24B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001494">
        <property type="protein sequence ID" value="KAG0009801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXC5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01087">
        <property type="entry name" value="Prolidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007865">
        <property type="entry name" value="Aminopep_P_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001131">
        <property type="entry name" value="Peptidase_M24B_aminopep-P_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052433">
        <property type="entry name" value="X-Pro_dipept-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43226">
        <property type="entry name" value="XAA-PRO AMINOPEPTIDASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43226:SF1">
        <property type="entry name" value="XAA-PRO DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05195">
        <property type="entry name" value="AMP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01011">
        <property type="entry name" value="AMP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00491">
        <property type="entry name" value="PROLINE_PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminopeptidase P N-terminal" evidence="7">
        <location>
            <begin position="9"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0009801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="616" mass="69681" checksum="D4941B961162FA54" modified="2023-09-13" version="1">MLARTGLKYPSKLHCEKVASFLSHEARSDAIILAKGSVTKNRDNTDTELEFRQESNFYYLTGVLEEDFYFAYDFHHNRSYLIAPDLDPAKAVWKGPSLSNNELLKKYDVDHVARYSGLLNLLKNELKPKKIHGWGQPENGHPLPNKALEHELKHYISHRLVHPKSGHKGHFEDTEVSYSHRPHEHGPYGDHNGHRCGHHRHGKHGPKKPEEITLFKALILARINKTPIEIALSRESTRITSDAHRLVMKSARPGMFEYQLEALFRYECGRQGAKAQAYLPIVGTGVNGAYLHYTRNDTQIKNGDLILIDAACEADCYGSDVTRTFPVNGRFSPEQADIYSLVLEMQTSVISSMGKDVDWAKMNILSQKIGIRGLKRMGILKGDDQDLYESTVIKIFYPHGLGHLLGLNVHDDGLGLAPQRPPSSVVDELMNNKNLPVELHPISSNTAEYLKDLPPPSTRRNKTLGSSFYATPSTLLEPGMLLTVEPGIYFNPAQIEYALNNPSISHYLDEPTLRRYMPVGGVRIEDVVLVLPDGTIDNITTAPKDPHQIEQIVQEGQRQHMESQKMDQDYALSEKKYQKEQIPSVSMDSRPQDRERGIKKRIGIFKKLLRAIRGIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXQ8</accession>
    <name>A0A9P6SXQ8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Galactose oxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_001500</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001341">
        <property type="protein sequence ID" value="KAG0010423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXQ8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093:SF18">
        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="336"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="274"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="406"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="274"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="301"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0010423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="637" mass="69784" checksum="E0A28DF71EAAC93B" modified="2023-09-13" version="1">MIDLSVSWNTTNPVFKALTCGPAGSSMPSTLSSDGKSWFVLSNNHTGFLYNMKSKTWNKTLTLKDRRNHKIHKSTAVTDPATGLIYIIESLLPKRHDFHNIRTVNLATNTADKLKLSTTTRELVSSTVTWSKSRNSMLSLFGRRKSNSRLAAFDPTTGWSTLTTTGDIPPMRTNGCFVSANGGTSAIYFGGFGYGQGGFHDIYVLNVTTLVWKRGPNLSKANRRGGASCAVSNNQFIAWGGFNSMNPKLPDSTLVYDLITHQWTPSYIASPSSLNKSSSPSSETPTATAPIVSSTPVAIETSTTTSPATTSSISSSNTQSALKANPQSNNSRGHTVVIVVAVIAAILVLLAIAGLIFCLRKRSIRRNARTMDGDILYNPSLASTTAINPMKSEIPAEPDQQRHFVTINNDPEPRSNLNFNPMPTAADPPQPPRDDLESPASSSDDDDDKSTLNESTPRQSKALDDSYWSIVLSMEQQQQKHRRRESDDSASTITSALTPPLLQNAEIFAFPLPPSPNTTTLDAIQQHKEKHGHGHFYDHNLGITNTTATMKNIIASASNNYDNDNDYDYDYDYDSDCSKRHSHIGMKYVKSESNDILEICYFPRPISHHATLRDVYDTLAAPPPVPIPVPNVDYGYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXS5</accession>
    <name>A0A9P6SXS5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribosome biogenesis protein NSA1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">WDR74</name>
        <name evidence="5" type="ORF">BGZ80_001436</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Component of the pre-66S ribosomal particle.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the NSA1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001326">
        <property type="protein sequence ID" value="KAG0010499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXS5"/>
    <dbReference type="OrthoDB" id="18388at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22857">
        <property type="entry name" value="WDR74"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037379">
        <property type="entry name" value="WDR74/Nsa1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16038">
        <property type="entry name" value="NOP SEVEN ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16038:SF4">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 74"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="185"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="410"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="201"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="433"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0010499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="462" mass="51017" checksum="6D1BB5B397D721D0" modified="2023-09-13" version="1">MSSQRFYTGDEQGLIKVVTITELPVVKVKRVRRGQPTPESPAKLVPTVETWGTPDRERAIQLLCWDHDKQHLVVARKNGLVQLIDPKNGGATVTEFKHKLGKEGKVDTVFVGLFANSESVITCTNTGVLSIQSIQDQSQTKVHNVGKDICRMRVHPKENHIVATAGKEQEFTIWDLNQLFEDEKAQAEESSMKGNKKGNKNGKSSSSASASKALASASASLPSTTKPAGPEARYKSKETLAKGQIFKAKNVKNDHLDLRVPVWNTDFHFLSQYDTTRVAVGTRNHQIRVYDTKSGARRPVVDAEVGDMPVVAMCNGKDGSEIVFSDTVTNVYSVDTLTGAIIGQYKGFTGVATALATFTPFNGESDTRHLVSVALDRCLRVHEMDNTRKLLHKVYLKQRMTAVVVGEYTPAEPVDDDEEGEGLKKKKNKAGEGEDDEDDDDIWESMGKLEDKKSKKRKTSKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXW4</accession>
    <name>A0A9P6SXW4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_001214</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001274">
        <property type="protein sequence ID" value="KAG0010744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXW4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03221">
        <property type="entry name" value="ABCF_EF-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000011">
        <property type="entry name" value="Putative ABC transporter ATP-binding component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050611">
        <property type="entry name" value="ABCF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211:SF129">
        <property type="entry name" value="ABC TRANSPORTER ATP-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211">
        <property type="entry name" value="ATP-BINDING TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="194"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="615"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="89"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="111"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0010744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="871" mass="95706" checksum="2F550045BEA6F863" modified="2023-09-13" version="1">MPVSVSTFLAALPAGVKFDDDIQEYLSSIIDGQTYESVDALREETQHFLIDAGMEDTASLDSFYAKFDNQFSSSTSDTSSKINVALEKLSVKDQGQGTEGESSGPDDKGQNKQSGSPSATKTTKSKPVKISKAAKKLAAKSSTLLSAAASVNGDGSASPVIGKDAFSGEGAIVEAFSQQSRFHEETIETLSKEVDLKQVNIIIGGQPLLQDTRLWFKSGTMYGFVGRNGTGKSTLLKAIGYGQLIGFPLNLRTLYIEQLPSETPENQTVVETVLKADTERTLLLGESKLLQQAINKYPRQLVKSIKKLEWERMKVKLAAQQKLAIRRSGKRGAEARELLLVVEEEEKAAKEAFEAIPIEGVEPTLDVLNQAHEMQESVYNKLQQIEADSAEARARELLKGLGFTAANQDLPIKQFSGGWKMRIALAQALFLKPDLLLLDEPTNHLDLPAIIWLQNYLLEHLSEDQTVVVVSHDRNFLNAVSQEIIRLRDHKLTYHPGNYDEYEMKMEDKAKMKDRIATALEKKRKYAQETINKQRAIMHKTGDDKRGGVIASRQKKLERLTGHNKTEDGKRFKQSYYAGFHHNMGIIVEREVPEPSVTIPLPMPKELRGNPTTLLSLNNVTFSYPGAPARKTGPVIQNVSLSLHQSSRIALLGPNGCGKSTIMSLLAGDITPTSGTVERFSSMVKIGYYSQHNVDKLDGYSTKSAMQYLMDTFPEEYKTQAAARKYLGSFGVAGQCAVLPMSTLSGGQKARVALAVCVHDGPQVLLLDEITNHLDMATIQGLIVALKEFSGAIVMVSHDAYFVKAVCEDEEDELTDEDDDDALIRAQEEAGVVYRVKGGKLIRLEGGVDEYVKVVVAENKKGMRGGAGRPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SY97</accession>
    <name>A0A9P6SY97_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">WD40 repeat-containing protein SMU1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_000684</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus speckle</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001148">
        <property type="protein sequence ID" value="KAG0011443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SY97"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016607">
        <property type="term" value="C:nuclear speck"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006595">
        <property type="entry name" value="CTLH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045184">
        <property type="entry name" value="SMU1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22848">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00668">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50897">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="CTLH" evidence="6">
        <location>
            <begin position="136"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="308"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="351"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="395"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="437"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="479"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="539"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="565"/>
            <end position="596"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00026184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0011443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="605" mass="67970" checksum="E83665DC6FB826D9" modified="2023-09-13" version="1">MPTLEPKDQGQDQDRSRTIKMALPDKENTTDLAQSTSSLHTLDLGHGLEANPSRRTISAVAASHSHVGMNPNRIRPTEDIFNPKDPHIREASSQFYLHPLDIMRMIMQYLADEGYHASQMTIQDESNVKWHEREENTNETRRLKKAILDGEWAEVDKICSKPLFKNQKSFLFAVYKQQYLEYIEHREMQKKRLKPLEQHQKTPVEFKDLCYLLTTKSIHDAPSFKNWEGIAQGRDKLVEQFQSMLEVENSVKDGSVYVPPNRLLNLLRQAVAYQIDVSRYHPRISPIVDTLLQDFSPFVIPNATKTIMQGHRGNVKCAEFVGIEGLSIVSGSSDNTLRIWDTETGSCLRILEGHSSRIWDVSSNDSGSNVASASGDSTVKIWDIKGSSDPCRATLSGHSGDVYTVKYHPTSAHVVSGGYDKIVRLHDLVTGQVVKTFSGHQLAVSKVILNPVGNLIVSGSKDNTIKFWDVVSGVCIRTITSHLGEVTSVAMNSNGTLLLSSSKDNSNRLWDVRMTRPLRKLKGHQNTSKNFIRAGFAHNSLLVGGSEDGLVYIWDQESGDILQKLQGHEAMVYNAVWSPKQSMFVSSSDDRTVRTWYYNALCDII</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYE4</accession>
    <name>A0A9P6SYE4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_000544</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001112">
        <property type="protein sequence ID" value="KAG0011632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYE4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0011632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="116" mass="12693" checksum="501ED208C5452A68" modified="2023-09-13" version="1">MGGIGQNADITASNLIYGVNEMYNWVEEEYGDNTLSTEGALILTGDCGRAIGTFEYMFHRIGRHNPELKRRMAINETLPQMSWTTGVAKAKATNVAKANTKSRDSILSGGLPPLSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYH8</accession>
    <name>A0A9P6SYH8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_000399</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001080">
        <property type="protein sequence ID" value="KAG0011833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYH8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0011833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="450" mass="51449" checksum="2120F1FFFFEC8091" modified="2023-09-13" version="1">MPRNPFELPEIRRRLALFVSVNDAISCMQVSKAFSEDFAYPIWHTIDFGTQAKVDQIYPTISNNYGQHIRVVEGVKEESQVGSLINLGVTSLSELEVVTEMDPLFQASLYDLIRKNRATLTKLKIHRKSGKRKPSSIIFLDSLMSTIHSLQPSKLSHLSIQWLTLTRDSLTSVLRCCPVLIGIDLWGVTLIPSRKVDDYQHAGVKVLETMVADSIVEGNPPLLAHFPNLDMWKTGDSSLPSEFPSQRVKDIISTWCPTLRCVESNFMPSPLLTHLIVNVFDCLTSLTFDYRKISPEMILALLHRPDNWIHLDTYVSQAGFYSKFEDDGIPEVMDHFQSSRWMVQSIMRCCRNLESFGFQDHEMDLDEIEQIPWVCEGLEDLKVRIKGLDTRDMIEGAISKWRVGRKERGSGDIIEDPVDQDQSIEARVARHLLRFKNLSTVWLGSKIWEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYK5</accession>
    <name>A0A9P6SYK5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_000258</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001049">
        <property type="protein sequence ID" value="KAG0012014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYK5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0012014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="177" mass="19668" checksum="FACF5A27C8E8258E" modified="2023-09-13" version="1">MPSSTFVNQDFFIKVLAVFSITVAFTRWFPDADLVAPEAHFSSYVQTFKNSSETALTLYAVHLVVDIIRVLTLGILVSTAFSFAFIGERFEIMSYLPLAFTFFIVTKDVLMLGVLHAFPESNDIAAAKVAELMPVSINVERVLIGYGAVCLAIGLHRWSNAIGRDKRQVIKEAKKTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYP3</accession>
    <name>A0A9P6SYP3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">TPR-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_000284</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in endocytosis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the YPP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001054">
        <property type="protein sequence ID" value="KAG0011988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYP3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051722">
        <property type="entry name" value="Endocytosis_PI4K-reg_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23083:SF464">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT DOMAIN 7, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23083">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN, TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13414">
        <property type="entry name" value="TPR_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14559">
        <property type="entry name" value="TPR_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="745"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="779"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="848"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="630"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="636"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="652"/>
            <end position="672"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0011988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="895" mass="99648" checksum="485D029E77D260F6" modified="2023-09-13" version="1">MTLSAKAQAIERDFQNARGKANYAAFPEFVRRYLKHNKDGIVLAYSALLEMAIGEAELKAQKIEKWSYLASLDDTPQSIAVSPRVKPESIQDAIQKLESVLSKGTDEHQEGAAIVLARAAMATDAPDRLQRVAHYLQNIQLPPVKLPSGYGFTLVVCGLTIKGIAFEEEDRISEAIVCYDHVSNLVQSNPHEKCEELSSWTEHALYRAGMLKLRQGQAVSWPSEFRAARRVTLYQYFSQALSTSFKAYTATNGTSTVIDEQSQFYPTALSQELAQIHAYWEDSLATITSFPKADEKNWRVLVMIEQIVEDRKLLGSGSDADKRALVETIYRASQKTFQSPRILRFLFFALLDLGQFDEAELALEGYLGMMQIKEESKDTVEEVLTHEQRVRQDIESEYDITTVMIAGSLLYGKELGKHIEALACADKALSYINKYLQQHESLAELLYSAYNHQGIAYGLQASNAHDPEKRPALYAKAIDSFTRSIEALPDAFEGHYLLALQLAEMREVPRAILSVKQSLGINPSHIPSWHLLVLLLSSQKDYERALDICSVGLRESEWDNPQTDGFTASQIDGEDYLALRVTQIALQDQINGPESSLELQEALFGLYNKVFATEPSALIENMYDVQSIRRRETTDSEVPSGSTVTGRPRASSILSSRSKAGTGSDISQAPNIGTLNSLEVPKANYASSITSSIGSTGSKIRRHATPVPVQQQAPLSRSGLSLPPTVQRATTKSILRTARANKTLISLWLLSASTFRRLGRFEDAMKSIEEAERVDPSNPDVWYQLGLLYSAQEDQESASVSFSKALALSPHHPACLTRLARSYLEAGSLEMAEGILETTTKSLGWDSAEAWFYLGKIFEESDRLTRAKECLWYALELESSRPIRGFVESVPRYLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZE7</accession>
    <name>A0A9P6SZE7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">WD40 repeat-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_010893</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000809">
        <property type="protein sequence ID" value="KAG0013728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZE7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030621">
        <property type="term" value="F:U4 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017070">
        <property type="term" value="F:U6 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.80">
        <property type="entry name" value="E3 ubiquitin-protein ligase SopA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19846:SF0">
        <property type="entry name" value="PRE-MRNA PROCESSING FACTOR 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19846">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25173">
        <property type="entry name" value="Beta-prop_WDR3_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141571">
        <property type="entry name" value="Pentapeptide repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="235"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="277"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="319"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="361"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="403"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="445"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="487"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="529"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="571"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="613"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="655"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="697"/>
            <end position="740"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0013728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="787" mass="86225" checksum="E5E1582DB990DBE0" modified="2023-09-13" version="1">MDLSPRDKEAFRILLDSDFNQLGIVYLKDLRTEIYDKHEENSGLEPRSSRRRSTSSVLSFEVPVLKEEPATSIEQFLLDSPFGTRNFVDEPSILQFLGERSQQQPVFKEQLLAIIERSKTDKMVRIAAANAITVLVRADVQFIGTDLRGIKIPGADLRYGMFDSARLDGADLRKTKLHNIWLRKANLDGAEMTGAQFGELPFLQENEAVRCVHIGMMAKLSLLVDTKTEKCFQTLQGRINGANCVVYSPCGNKVATGGWDKTVRVWSVDTGECIHILQGHTERVRMVAYSPREDQIASVSLDKTARLWNVEAGECIHVLQGHNGKVSGVAYSPNGGQIASASEDGTVRLWDVETGDCIHNLQAHADMVGHVAYSPNGRQIASGSDDKTIRLWDVDAGNCIHTFQGHSFPIWCIAYSPNGNQIASGSYDKTVRLWTVESNYFARSTLSHIGSVRSVACSPNGGRIASGSEDKTLRLWDVETGTCVDSLQGHSDWVCSVAYSPKGDQIASGSADMTVGLWDVETGNCVHILQGHNNVVCSVAYSPNGDRIASGSDDQTVRLWDVETGECVRVLQGHVGDVNCVAYSPNGNQVASGSHDETVRLWDIETSNIIHTLQGHRDHVYSVSYSPNGDHIASGGKDNVVRLRSVETGNCTHTLHGHDNAISSIAYSTDGDQIASGSHDKTVRLWDVHTGQCLAVVSSFNGTVYSVAWKITMNGQYLVTGSTDKSVRHWEIAREQDEYTVRLCWSSSHEGLTVIDASFKDVRDLSKMNQTLMGQRGALVGSSSSVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZG5</accession>
    <name>A0A9P6SZG5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Radical S-adenosyl methionine domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">RSAD1</name>
        <name evidence="2" type="ORF">BGZ80_010809</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000795">
        <property type="protein sequence ID" value="KAG0013839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZG5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006779">
        <property type="term" value="P:porphyrin-containing compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034505">
        <property type="entry name" value="Coproporphyrinogen-III_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010723">
        <property type="entry name" value="HemN_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13932">
        <property type="entry name" value="COPROPORPHYRINIGEN III OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13932:SF5">
        <property type="entry name" value="RADICAL S-ADENOSYL METHIONINE DOMAIN-CONTAINING PROTEIN 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06969">
        <property type="entry name" value="HemN_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HemN C-terminal" evidence="1">
        <location>
            <begin position="238"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0013839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="314" mass="35372" checksum="A37052B95EABAB1D" modified="2023-09-13" version="1">MATDLEPFSVYVHWPYCSSKCTYCNFNKYVDPHADNERMELSLLKELKTEISYWGLDNKTRPVRSVYFGGGTPSLARPNMFDTILSTLDQLCGLSKDTEVTVEGNPSSHILKELGRDHTPSSALRSLLDARSKSYQLTKMFMRRLHKDVTQGKVTLPDSELAADMYETMIEMTSEAGFEHYEVSNFAKNQAYRPGAHGRMRNPKSGELQRTFNIRDPAGWMQQCSEVGTGRRRTVAIDPEETKQELVALGMRTKRGVELEMFKKATGQELIKYLNTEALTTCVEANLVVLSPQALSPTERGMAVADELVARLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZM3</accession>
    <name>A0A9P6SZM3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ca3427-like PBP 2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_011425</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial solute-binding protein SsuA/TauA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000918">
        <property type="protein sequence ID" value="KAG0012906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZM3"/>
    <dbReference type="OrthoDB" id="1363at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054364">
        <property type="entry name" value="Ca3427-like_PBP2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30024">
        <property type="entry name" value="ALIPHATIC SULFONATES-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30024:SF47">
        <property type="entry name" value="TAURINE-BINDING PERIPLASMIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13379">
        <property type="entry name" value="NMT1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22384">
        <property type="entry name" value="PBP2_Ca3427_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Ca3427-like PBP 2" evidence="4">
        <location>
            <begin position="93"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF22384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0012906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="322" mass="35474" checksum="712D468672961B89" modified="2023-09-13" version="1">MVASTQTVLRVGFVPEHFSSPLHMAVELGFFEKEGVIVERVCCPSGTGEMTAKLIDGSLDVAIALTEGLLAGIAKGHDAYKIIGTYVKSPLCWAISVGQNSRHVDRKSLRDGTIGISRVGSGSHIIPYVLAEQEGWLKGSSPSDPEYKAPFEFKVLNTFQNMRDSVNDGSSDAFLWEKFTTKPYHDSNEVRSVDTITPPWPSFMIAASVRHLPMSDDPQRQTILAKFLRGLSNATQHFVDPENYNESIAFVQQKMSYTQQDVQDWFSGVCYPKEGCSVVSRESLITCASILVKAGVLQKEQEKDVKASVDTKYVDANVAQLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZR2</accession>
    <name>A0A9P6SZR2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">60S ribosomal protein L35</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPL35_2</name>
        <name evidence="5" type="ORF">BGZ80_010469</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL29 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000730">
        <property type="protein sequence ID" value="KAG0014403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZR2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
        <property type="term" value="P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00427">
        <property type="entry name" value="Ribosomal_L29_HIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.310:FF:000002">
        <property type="entry name" value="60S ribosomal protein L35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="6.10.250.3450:FF:000001">
        <property type="entry name" value="60S ribosomal protein L35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00374">
        <property type="entry name" value="Ribosomal_uL29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001854">
        <property type="entry name" value="Ribosomal_uL29"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018254">
        <property type="entry name" value="Ribosomal_uL29_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045059">
        <property type="entry name" value="Ribosomal_uL29_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036049">
        <property type="entry name" value="Ribosomal_uL29_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00012">
        <property type="entry name" value="L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45722">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45722:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL29-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00831">
        <property type="entry name" value="Ribosomal_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46561">
        <property type="entry name" value="Ribosomal protein L29 (L29p)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00579">
        <property type="entry name" value="RIBOSOMAL_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="72"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0014403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="188" mass="21897" checksum="4447B88DD996F8F5" modified="2023-09-13" version="1">MINFFKSINWIQSTFTLNRQGSQSGSDFDCRNQQTRTYQDPLHHGNLSLWLGSDRVFNLFYFVIVQAAVKAYELRTKNKAELTKQLEELKQELSSLKVQKVAGGSASKLTKISTVRKSIARVMTVITQTQRSQLRLFYQKKNFLPLDLRVKKTRAIRRRLTKNEASIKTVKQQKKETHFPLRKYAIKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T098</accession>
    <name>A0A9P6T098_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Histidine kinase/HSP90-like ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_009890</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the heat shock protein 90 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000634">
        <property type="protein sequence ID" value="KAG0015375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T098"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16927">
        <property type="entry name" value="HATPase_Hsp90-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.565.10:FF:000005">
        <property type="entry name" value="Heat shock protein 90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.790">
        <property type="entry name" value="Heat shock protein 90, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00505">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037196">
        <property type="entry name" value="HSP90_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001404">
        <property type="entry name" value="Hsp90_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020575">
        <property type="entry name" value="Hsp90_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003555">
        <property type="entry name" value="PRK05218.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11528">
        <property type="entry name" value="HEAT SHOCK PROTEIN 90 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13589">
        <property type="entry name" value="HATPase_c_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00183">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002583">
        <property type="entry name" value="Hsp90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00775">
        <property type="entry name" value="HEATSHOCK90"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110942">
        <property type="entry name" value="HSP90 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040486454" description="Histidine kinase/HSP90-like ATPase domain-containing protein" evidence="7">
        <location>
            <begin position="20"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase/HSP90-like ATPase" evidence="8">
        <location>
            <begin position="58"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="247"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="247"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="259"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="131"/>
            <end position="132"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="404"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR002583-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0015375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="813" mass="91631" checksum="90E8A3387DC8297E" modified="2023-09-13" version="1">MKKSFLLLSILAAISVVAAEAPAAQAAFNTPGEKGEKYQFQTEVARLMNIVINSLYKTPEIFLRELISNGSDALDKIRFKSLTDPTALESNPNLNVTIALHKDQRVITITDTGIGMTKEDLQKNLGTIAKSGTSEFLDTLSGDKADMDLIGKFGVGFYSVFLVADKVRVTSKNNNDDQYIWESTAVDDFTIAKDPAGNTLGRGTQIAIHLKEDQDQYLEDARIKELVTKYSEFINFPIYLRQTKTKEVEPEPVAKETKDDDDEEAVVEEAKDDDTKEKAEPVIVAYEEDDLMNSNKPIWIRDPKTVTEVEYQEFYPVLTREPGAKAMAHSHFKAEGDVDFKAIMYIPSVAPKDLLQRVDSVHRNVKLYVKRVFITDDFPDILPRWLSFLKVVVDAEDAPLNVSRETVQSNKGIKAISKHIIKKLFDLLKTLSQDEERYAGFIKEFGTSLKLGALEDKSNVKKISRLLRYRSSDSDKYTSLESYVSRMKKGQKDIFYFTGANVDEIKQSPFVESLLARGYEVLYMDDPVDEIVLTHLGAFEGKSFQNVGKSDLNLGDENEAEANKELETKFLPLLDWMQATLLNDVEKVRVSKRLTTSPAALVANDFGWTANMERLMEGQAKQNKDQGMHQFMKNQKKIFEINPGHPLVLGMLERASKDPEGFENDKQFQEMTRILYDITLVRSGYALKEGVKSFAGRVENMLRVNLNVDTNAEAIYDAPKAEPRDQEEVQAEIDEREDILDADEKKPGTMTAEELNKMLKEFTDSTNPPMPGKKAVPGGRKAEVNVDDIVAKLEAELDLEDVETPKETVHDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0T1</accession>
    <name>A0A9P6T0T1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_009238</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000535">
        <property type="protein sequence ID" value="KAG0016413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0T1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040386291" evidence="2">
        <location>
            <begin position="22"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0016413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="75" mass="8007" checksum="8218D740AA34E2A3" modified="2023-09-13" version="1" fragment="single">MVKYFFSSIAALAMTLAAVQAKLQGYPPADKVPSVTSAEVKAWLKEIDLRGAPNVPIAKATPGEPPKCNKKQLPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0U9</accession>
    <name>A0A9P6T0U9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Snf7 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_009252</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SNF7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000538">
        <property type="protein sequence ID" value="KAG0016380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0U9"/>
    <dbReference type="OrthoDB" id="3973241at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005771">
        <property type="term" value="C:multivesicular body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032511">
        <property type="term" value="P:late endosome to vacuole transport via multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006900">
        <property type="term" value="P:vesicle budding from membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005024">
        <property type="entry name" value="Snf7_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22761">
        <property type="entry name" value="CHARGED MULTIVESICULAR BODY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22761:SF12">
        <property type="entry name" value="CHARGED MULTIVESICULAR BODY PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03357">
        <property type="entry name" value="Snf7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="27"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="120"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="222"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0016380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="340" mass="39414" checksum="9CCF0F48F220BD65" modified="2023-09-13" version="1">MHRFFGTNKKTPKPNLTDAITATDLRVDAVEVKIRKLDAELIKYKDQMKKMRDGPAKNSVKAKAMRILKERKLYESQREQLQQQSFNMEQAAFTTENLKNVMTTVDAMKLANQTMKQQYKKVDIDKIEQMQDEMEEIMEQANEIQETLGRSYGVPDDVDEDELEAELDALGDELYEEEEPSYLEDEALDLPAAETAEPQTEDTPSEKENTNALRTRFTGACRDALRAECKQYESDYEQKLRQAEVDFRRTKLELKEQKDRQQMDAVRRVMNNLAQSNEYKGSSDGTQKRLEKIRSWIDYAASKADEHWTKERQQFDAKYGYTKTAAVVEAPVAEEKNPSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0W2</accession>
    <name>A0A9P6T0W2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 11">Chitin synthase</fullName>
            <ecNumber evidence="2 11">2.4.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">CHS2_3</name>
        <name evidence="14" type="ORF">BGZ80_008762</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10 11">Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>[(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n) + UDP-N-acetyl-alpha-D-glucosamine = [(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n+1) + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16637"/>
            <dbReference type="Rhea" id="RHEA-COMP:9593"/>
            <dbReference type="Rhea" id="RHEA-COMP:9595"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17029"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="EC" id="2.4.1.16"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Cell membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the chitin synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.16" evidence="2 11"/>
    <dbReference type="EMBL" id="JAAAID010000487">
        <property type="protein sequence ID" value="KAG0016934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0W2"/>
    <dbReference type="OrthoDB" id="26569at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030428">
        <property type="term" value="C:cell septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004100">
        <property type="term" value="F:chitin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006031">
        <property type="term" value="P:chitin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04190">
        <property type="entry name" value="Chitin_synth_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004835">
        <property type="entry name" value="Chitin_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013616">
        <property type="entry name" value="Chitin_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914:SF9">
        <property type="entry name" value="CHITIN SYNTHASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01644">
        <property type="entry name" value="Chitin_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08407">
        <property type="entry name" value="Chitin_synth_1N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="4 11" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="499"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="539"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="583"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="609"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="688"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="790"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="830"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin synthase N-terminal" evidence="13">
        <location>
            <begin position="119"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="26"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU366040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0016934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="861" mass="97232" checksum="52EC7AE2A0C72239" modified="2023-09-13" version="1">MSRNNQYPPQGGSPQQQPYYAGPPQRTQTNHSAHSVRTPVSPRMNNQYPPDQPIGYSGPPSPSSYVAHQGYDIDDSDGARLMNNQGRVGGQYPNGLTAVPRSVSLKLDRAATMNRRSIVHVPLTDGNLVMDCPVPRQLLHNVHFKGEREFEFMRYTAATCDPNDFCKERYTLRPTIYRRQTELFIVMTMYNEDDELFIKTMGSVMKNIAHLCTRSKSKTWGKEGWKKVVVCVVADGRKKCHPRVLKVLAAMGAYQEGVAKDTVAGKPVTAHIYEYTSQIVVDQDLKTRGADAGIVPVQILFCLKEENKKKLNSHRWFFNAFAPQLNPNVCILLDVGTKPSGTSIYHLWKAFDRDSSIGGACGEICADLGPNCANLMNPLIASQNFEYKMSNILDKPLESVFGYISVLPGAFSAYRYKALLDSSPGVGPLSSYFKGETLHSSGDAGIFESNMYLAEDRILCFELVAKKNEAWLLRYVKSAKASTDVPDNIAEFISQRRRWLNGSFFAAFYSLAHFTRVLTSGQGFFRKFFLMFEFLYNAVNLVFNWFSLANFYLTFYFLTIAAANNPNPNFKPFGTWGEVTFSVLRNVYIAAIITVFLCSLGNRPQGSRIIFILAIILFTIIMGVMLYLAAVTVYLVVQPVWGHYSEMIALLKTQGAFRDTVISLLSTYGLYMISSLMHFEPWHMFTSFFPYMFLLPAYVNILMVYAFCNTHDVSWGTKGDNKAPELGGAHKVTKDGKEVIKLEKPSNREDIDAIYQLNMQELSVRPDAVKEKRDQKTKQEDYYKMFRTRLVLTWMFSNALLIIIMTNSFTTDTDADKKTSTVSSDEMFNPYLSVIFWSVAALGAVRFVGSTLYLIMRLLFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0W9</accession>
    <name>A0A9P6T0W9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Nucleoporin pom152</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_008833</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000493">
        <property type="protein sequence ID" value="KAG0016880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0W9"/>
    <dbReference type="OrthoDB" id="5529162at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070762">
        <property type="term" value="C:nuclear pore transmembrane ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006999">
        <property type="term" value="P:nuclear pore organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056541">
        <property type="entry name" value="Ig-like_POM152"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056542">
        <property type="entry name" value="Ig-like_POM152_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056543">
        <property type="entry name" value="Ig-like_POM152_9th"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056544">
        <property type="entry name" value="Ig_POM152"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037701">
        <property type="entry name" value="Pom152"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28206">
        <property type="entry name" value="NUCLEOPORIN POM152"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28206:SF1">
        <property type="entry name" value="NUCLEOPORIN POM152"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24312">
        <property type="entry name" value="Ig-like_POM152"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24519">
        <property type="entry name" value="Ig-like_Pom152_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24527">
        <property type="entry name" value="Ig-like_Pom152_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23664">
        <property type="entry name" value="Ig_Pom152"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nucleoporin POM152 first Ig-like" evidence="3">
        <location>
            <begin position="31"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleoporin POM152 Ig-like" evidence="2">
        <location>
            <begin position="280"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleoporin POM152 immunoglobulin-like" evidence="1">
        <location>
            <begin position="381"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleoporin POM152 Ig-like" evidence="2">
        <location>
            <begin position="583"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleoporin POM152 immunoglobulin-like" evidence="1">
        <location>
            <begin position="723"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleoporin POM152 ninth Ig-like" evidence="4">
        <location>
            <begin position="917"/>
            <end position="985"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF23664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF24527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0016880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1110" mass="124283" checksum="751021F1B7977492" modified="2023-09-13" version="1">MIEMTHNLDNYIDKDEHLLGRHTILIKPYSSAILNPDDQCFCVPDTNTPIDLPGIPIVFNGSEPHYLEYTITSFETGETTVHKLSGPFKESSQVLQKFRSSHEDAKSIYKLRASTSGAYKLQRILDKDRVDVRFHHGREVYVVNCPEAHIDHYKDTLDYCVGKGDVDIPITVRGLPPWTVTYKRYVGTGNNAHDLLIESEPPGYSSPFLLGWSPPATPNYSWAKQQEMNLSVNLGLSVPGKYGFQLTKVKDGCGNVIDFQGLVAKNLRDPEIRRVNIRERPSVSMKCDSQRPIKIVDRGGASPATIGLKMKRGDAPFQVGYVYQKSDLDEPQVMPAVQFKEGDAAYIDAKLPGVYTLSYIKDAFCEGEIESPRDCSVIVATRPTVDIVSHPINDSCVGAIGVTVDATFTGEGPWEVCFHVWRNGTPESKQTCHSSSKPRLNLELKPRLPGNYEYKFTTVSDKNYYDVKVDLPSVFQNIHPQPSAVFVDNQSGMKTCRGSSKTLDVELYGTGPWDIEYRVIRGTEIKLFKEQNINQKITTLTLPPFEQEGTYSIDLGKVTDLANRCEKDLNVADVTIQVSNGPPTVSFQCDKPVEFAEGDKVNLPIHLTGGTPWKITYGIEGEESLIPDKKDSRNTFITVDRPGVYELKSVSDSFCEGEVVEQARKCEVVYSKQPAMNLMIDSIRFRGGPRENVPEGEIAPSERITRDGEFFILPAVCKDADRTLELRLTGKAPFVLRYRAIYKPTKGGKDVQTLHEERSQHSTMRIPIMTDQAGAVSYHFETISDAIYQNVEVRHEKKAVVFKHVIRTPPTARLVNTAQQLYCKNEVTGVKEKISIQIQDGVGPFSLAVEIMRPNQALAEKLFEHDVVPRNGIYEWTLPAKFTEMGLYKVSILRVTDVNGCSSGAASTVEFDILDTPSITPLRSIKDACVGDKIEYSIQGEAPEFRVFYSVDQTNYDTPLDSKQRIFSLEATKPGLVKINKVCQTLTKKQKKECCTQPVEEMSTMIWAIPTVKVADGTNLITDLREGDLAEVVATFVGEPPFSWGYVRTEAVYDKEGQVKHGKRPVPLETKKKENIPGHKFSFFTATEGTIVPVWIKDKHCQFGKEIKET</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0Y3</accession>
    <name>A0A9P6T0Y3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">2-(3-amino-3-carboxypropyl)histidine synthase subunit 1</fullName>
            <ecNumber evidence="3 11">2.5.1.108</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">DPH1_2</name>
        <name evidence="13" type="ORF">BGZ80_008627</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>L-histidyl-[translation elongation factor 2] + S-adenosyl-L-methionine = 2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor 2] + S-methyl-5'-thioadenosine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:36783"/>
            <dbReference type="Rhea" id="RHEA-COMP:9748"/>
            <dbReference type="Rhea" id="RHEA-COMP:9749"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:29979"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73995"/>
            <dbReference type="EC" id="2.5.1.108"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="11">Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 11">Protein modification; peptidyl-diphthamide biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the DPH1/DPH2 family. DPH1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.108" evidence="3 11"/>
    <dbReference type="EMBL" id="JAAAID010000473">
        <property type="protein sequence ID" value="KAG0017087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0Y3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090560">
        <property type="term" value="F:2-(3-amino-3-carboxypropyl)histidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017183">
        <property type="term" value="P:protein histidyl modification to diphthamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11850:FF:000001">
        <property type="entry name" value="2-(3-amino-3-carboxypropyl)histidine synthase subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11860:FF:000002">
        <property type="entry name" value="2-(3-amino-3-carboxypropyl)histidine synthase subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11840">
        <property type="entry name" value="Diphthamide synthesis DPH1/DPH2 domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11850">
        <property type="entry name" value="Diphthamide synthesis DPH1/DPH2 domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11860">
        <property type="entry name" value="Diphthamide synthesis DPH1/DPH2 domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016435">
        <property type="entry name" value="DPH1/DPH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042263">
        <property type="entry name" value="DPH1/DPH2_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042264">
        <property type="entry name" value="DPH1/DPH2_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042265">
        <property type="entry name" value="DPH1/DPH2_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035435">
        <property type="entry name" value="DPH1/DPH2_euk_archaea"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00322">
        <property type="entry name" value="diphth2_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10762:SF1">
        <property type="entry name" value="2-(3-AMINO-3-CARBOXYPROPYL)HISTIDINE SYNTHASE SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10762">
        <property type="entry name" value="DIPHTHAMIDE BIOSYNTHESIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01866">
        <property type="entry name" value="Diphthamide_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004967">
        <property type="entry name" value="DPH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00032">
        <property type="entry name" value="Radical_SAM_3-amino-3-carboxyp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="297"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR004967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0017087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="328" mass="36656" checksum="C4F27B20970BA34F" modified="2023-09-13" version="1">MGDVTYGACCIDDFTAVALGCDFLVHYGHSCLVPVDVTTIKTLYVFVDIGIDVQHFIATVRKNFEPRSKLVLVGVIQFVQAIQAARRELEVDYILNVPQAKPLSPAEILGCTSPQLPKGEDALIFLGDGRFHLESMMIHNPDLPAFRYDPYNKKFTRERYDHADMHSLRKHAIETAKKAKRFGLILGTLGRQGSTSILDHMEAKLKERGCDYTIILLSEIFPGKLAMFEDMDAFIQIACPRLSIDWGYAFAKPLLTPYEASVVFESVPWQEVYPMDFYSNDSLGPWTVNHGRNVRKKASGAGAKSINSRLKAHDNSVVSEEPPAPTTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1K5</accession>
    <name>A0A9P6T1K5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">PA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_008543</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the IFI6/IFI27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000466">
        <property type="protein sequence ID" value="KAG0017189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1K5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009311">
        <property type="entry name" value="IFI6/IFI27-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038213">
        <property type="entry name" value="IFI6/IFI27-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046450">
        <property type="entry name" value="PA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16932">
        <property type="entry name" value="INTERFERON ALPHA-INDUCIBLE PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16932:SF18">
        <property type="entry name" value="INTERFERON, ALPHA-INDUCIBLE PROTEIN 27-LIKE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06140">
        <property type="entry name" value="Ifi-6-16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52025">
        <property type="entry name" value="PA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="46"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="365"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="PA" evidence="8">
        <location>
            <begin position="153"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="296"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="301"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="314"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0017189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="464" mass="50214" checksum="57661066301B4FB5" modified="2023-09-13" version="1">MRRNSERPRAWYCRFDDQDEANEPLLSEYVSEIARKGKARNPIKRYFFAGVCVWFVLLSVGYLFSRSLYWRYKLGTTHDEVLVPVQNSPSDSGDGTKDVVTVPREPGVSQLWCLGLRSDKNQETYFKDKADFQNLKHNTLSTTISMQKIQAIENDGCQAADHEMATGKVTIVQDGSSDCDLWTIAHLSEKAGALAVLFYHSHTSTENDLALSSSLLAQEWKQGDILVSIPVLSITRSLGVTLLKYQSDVLVSLTTVDILEKPTEDGGVNIVDRILAPFKQFWEFLTGLFGSKPIGDDTPADSDKPADSDKPAGDDEPIGDNDPTEDGGDSTSIVDKILALCKQFWEFLSGLSPLPGCLWTVKYQVMLGSLIGAVLLPVAFILFPVALGFGVEGIYAGSCAATCMACHGGYTPAGGFVAVMQSCGTLGIYAGLNPFTVATGAIAGLIGGGYYGITVLDMCAPPPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1R4</accession>
    <name>A0A9P6T1R4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tau 95 subunit of transcription factor TFIIIC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">TFC1</name>
        <name evidence="3" type="ORF">BGZ80_007102</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000358">
        <property type="protein sequence ID" value="KAG0018491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1R4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000127">
        <property type="term" value="C:transcription factor TFIIIC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001002">
        <property type="term" value="F:RNA polymerase III type 1 promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001003">
        <property type="term" value="F:RNA polymerase III type 2 promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006384">
        <property type="term" value="P:transcription initiation at RNA polymerase III promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.160">
        <property type="entry name" value="TFIIIC, subcomplex tauA, subunit Sfc1, barrel domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040454">
        <property type="entry name" value="TF_IIIC_Tfc1/Sfc1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041499">
        <property type="entry name" value="Tfc1/Sfc1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042536">
        <property type="entry name" value="TFIIIC_tauA_Sfc1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13230:SF5">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13230">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIIC, POLYPEPTIDE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17682">
        <property type="entry name" value="Tau95_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transcription factor IIIC subunit Tfc1/Sfc1 triple barrel" evidence="2">
        <location>
            <begin position="49"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0018491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="218" mass="24394" checksum="683D2CBEE8A33874" modified="2023-09-13" version="1">MAASNRKLSKIEQVPDAKFFSVEFPGHVENVNKALEALGGKRAITDAISTGNFLLKATRRYKVKRRLGSERSLPPYRAPRDDDVPYDKDVEYRFEVLGAIPKTVRFSGLADYQHIVDPKDEIVRIKSDLQNMEYENLISVKLDNTDPTEDISMTQLVPPGAISKSGVPHPFRYKARERDDAVKAKPGRKKKPSFRPKKQPGDLTGIAPVESNESGDDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1T0</accession>
    <name>A0A9P6T1T0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">HpcH/HpaI aldolase/citrate lyase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_006802</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000338">
        <property type="protein sequence ID" value="KAG0018738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1T0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006107">
        <property type="term" value="P:oxaloacetate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005000">
        <property type="entry name" value="Aldolase/citrate-lyase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011206">
        <property type="entry name" value="Citrate_lyase_beta/mcl1/mcl2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32308:SF0">
        <property type="entry name" value="HPCH_HPAI ALDOLASE_CITRATE LYASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32308">
        <property type="entry name" value="LYASE BETA SUBUNIT, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G13030)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03328">
        <property type="entry name" value="HpcH_HpaI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015582">
        <property type="entry name" value="Cit_lyase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HpcH/HpaI aldolase/citrate lyase" evidence="7">
        <location>
            <begin position="23"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="313"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="321"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR015582-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR015582-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0018738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="340" mass="36941" checksum="DE514C6D528F3DA1" modified="2023-09-13" version="1">MLTAFRSGAPRGILTRTLGATHVPGSDERKLKSSLSLSADCLVYDLEDGVSHNRKNIAREMVFDALEASEHRKAEKAVRINAVGSGLEFDDLNVVLRSSRLQAIVIPKVQSAKDIQFVSQMVDSVAPSITRKNVKILASIESALGVMNLKEIATADPRVDALVFAAEDYCADLGLTRTREGTEMLYGRSAIATAAHAYGLQAIDLVCMDYKNDEILKEECEFGRRMGFLGKQAVHPRQLDIIQRCFLPTDHEIARAADIYEGYQEHSKRGVGVFNYNGKVIDLPVVKWAGKILSRARQGGVAIPSPEERQKILQVGPSPAPNSTSASVNTAGKSDGSTTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T264</accession>
    <name>A0A9P6T264_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Hemimethylated DNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_007156</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000361">
        <property type="protein sequence ID" value="KAG0018458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T264"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.390">
        <property type="entry name" value="Hemimethylated DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011722">
        <property type="entry name" value="Hemimethylated_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036623">
        <property type="entry name" value="Hemimethylated_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032698">
        <property type="entry name" value="SirB1_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02097">
        <property type="entry name" value="yccV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31350:SF21">
        <property type="entry name" value="F-BOX ONLY PROTEIN 21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31350">
        <property type="entry name" value="SI:DKEY-261L7.2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13369">
        <property type="entry name" value="Transglut_core2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08755">
        <property type="entry name" value="YccV-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00992">
        <property type="entry name" value="YccV-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141255">
        <property type="entry name" value="YccV-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hemimethylated DNA-binding" evidence="2">
        <location>
            <begin position="681"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="570"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="785"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="587"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="612"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="648"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="789"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="807"/>
            <end position="822"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0018458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="866" mass="97219" checksum="1071E7313382C0D7" modified="2023-09-13" version="1">MQSKPTPALPEDCVFVVLQYLTAEVHQNANPHNELDSVLDGMSLDPVKGKAWFPPETLPNIHAPEQWYSTLYPPYDLDSWKDVYRERHQKDATVRLLLEEIVGDSRNRMRHMDGIAKIGMIHARDVLDNIIAGCNGEERDLTRTYYARKTLKRLQRGWVLDQWRAYRMNSQSFPIWQGCGLMAMFSNHEMELSDIDCLLQDLADEFLEISPLQNVDHGSPAVLPTVITPNNLDRYGPGSFSTSPDNHPGPERNGPDSSSNKYSRYYEAQIDRLKQLIQFFTQEKGFKGNTDNYYDPFNSFIDKVLIRKVGIPISLCIVFDELARRAGIVGVELMGFPQHFMIRYRPQAPVFDPITSPLPSSETSVTSPPPPAPPTYFLDLFHPPHRLLSMEEYEDYFTRLGVPRPPDIYRDLPTPPLEIFLRCLRNIILAVEQTGGAGRIGSDHQASLYSGITQLLTLHPSEEWGLYVLWLKYLSNFWPEDIGLIRASIKDMEWTDHRRSAARGHMSSSSTTPNQGQSQHIFGYNQGVIYNTEHAGSGSSAHFTSSTHETIKILRAQVRELEIADETGEVGHIRRRRRPRVVPASAAQATSQSNIPQQHDTTAESIGDEAQSSSTGNPITSSSAIDEASSHAQHSLERQDSTLEEQQNELTNSGGNSETAVSEYSPKVATTLGGEERRRPEPEYYVGEVFRHLIYRYPGAIYGYDLKCEAEEEWIRSMAIDTLKYGRHQPFYNALLSDGSRRYVAQENIHVLYREYRNTDASPLAPADQILSSLASNAASTSMPENVDASISSSQSSMSAGSSLSAPTTGETASSSGPPASLQYSELGPLGIEAVGQYFEAWDGQHGHYIMNKELRKLYPTEDYAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2G7</accession>
    <name>A0A9P6T2G7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Auxin efflux carrier superfamily</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_004747</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000239">
        <property type="protein sequence ID" value="KAG0020111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2G7"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004776">
        <property type="entry name" value="Mem_transp_PIN-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31794">
        <property type="entry name" value="AUXIN EFFLUX TRANSPORTER FAMILY PROTEIN (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31794:SF4">
        <property type="entry name" value="AUXIN EFFLUX TRANSPORTER FAMILY PROTEIN (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03547">
        <property type="entry name" value="Mem_trans"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="47"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="92"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="247"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="287"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="434"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="466"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="499"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="309"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="374"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="376"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0020111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="526" mass="56771" checksum="79891C1C2A76B925" modified="2023-09-13" version="1">MASTISWSQFKAYWPIPVFYTIFSFVSFLVAKVGSRLLRFSKDEEKFVIASVLFSNTNTLPLALLQSLAFSAAGDRLLRDENDTKEDVAARGISYILFYAIFGNLVRWSYGFSLLVPKDKPEEIEGEEGEESWDSNLQLPSPSVLINVDMSASRNSDASILTLPASFDTPRVADTHDVDSSIAPTAFKNPNLAANNSSYLHPHSVSTYPCPAKKSPTMSIENISGSVVVRVASTAYERVRKVMTPPLLTALISLVIGLVPALHQLFMSPHSSVYRYLVRPIEGCGNAAIPMILLCLGAQVVHFATSSRQNKLPVPSGHPGLRIYNSSSHDGSSSDEEGSPGSQPPHKSYNSIARSSTSSTATLHHFNQPSDQLIGSQVSSRSLRGSTSSAAASEGSDEDESSPLIGPTGTSAVAKSSDESHYLIPCVTPVSFSLLARMLIIPVVCMPAIMFHPGSLSPILTMDPTFSLTLVLLVAAPTAINLIQICQIKGFFEMEMASVLFWSYCVLGIPCILGWSLIGLWVAGKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T496</accession>
    <name>A0A9P6T496_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_009104</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000052">
        <property type="protein sequence ID" value="KAG0023545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T496"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005847">
        <property type="term" value="C:mRNA cleavage and polyadenylation specificity factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031124">
        <property type="term" value="P:mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045245">
        <property type="entry name" value="Pfs2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22836:SF0">
        <property type="entry name" value="PRE-MRNA 3' END PROCESSING PROTEIN WDR33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22836">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="155"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="383"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="603"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="55"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="155"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="392"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="420"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0023545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="849" mass="95496" checksum="CC19AE3FCB3D334D" modified="2023-09-13" version="1">MRMLDQQRAAQIAQQQQQQQQQQSAKIQRQYQPHQQMYPHHSSSKPVPIQPHPTSQQQQQQQASRSSSLQQQYQQQQQMVQQQLIQRYQQHRQHQLKQQQARQLQYLRQRTAAQQASAVPTTGSFNAGLADRPDRNKSVISQECSNCMALDSLVPQSRTESHESSTSGAASTSVDGGKSHGKPRPVPPYRVNYLKKIHYQFKKILQEARFQGWQDAQVLEIEDRISERDFHTVFYAGIEDGLVMSDPARSRQTSASASSTASSSPLLASKSSVVIAGAEPIVIKIEDDDEETSGSLLASKPSKEVRTFSSEASVGELFGQRWKTEPMVGYTLVHFGGSDRTRMVPMNPTVPSLTVTFDRESKSVTFAFRVLVNGLCLLSSGGGPPALHMPEMADDEESETEEQEEASETTDNQRKAGASDTERVQKDSRSRPTTPETHERERSASSGTGMDADKPQIKKPLASRHRNVGNAAANGQQAAPAVPRMLRRTTKQSFMDVDLQYLMNLDPSTPDPFENSSPIFDDPPSLFRPLPASIMGVGGPGTGEWMSTEAIRLQKEQEELRGQYLQFLHQLHQNNAHGFLVHMNTFASEFPQEFAQLQAYIRYQEQVTNQQRLEAQRQEEMRQYQLQLEQRRQQEQELNQFKQFQEMQLQQEQIHEMQELLQEWLLKRQQLRATSFRIGTNSKEDGLDLADVFTIALQRDPKLVERMMTTAGPGQGLSLLLTPSQQQEFAEFLEKRRIQDVMAQEKKKQDLFAAGFSGLGNYQSFSTPTFGMPSSSSSSSSSQLAAAAAANLLTSSLWNNNNNNNSNAASSWLNGLTTSNLKATPSHFQYPMTNEQFLKKNSKGSGRKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T4V2</accession>
    <name>A0A9P6T4V2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF676 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_006080</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the putative lipase ROG1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000003">
        <property type="protein sequence ID" value="KAG0024806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T4V2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007751">
        <property type="entry name" value="DUF676_lipase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044294">
        <property type="entry name" value="Lipase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12482:SF62">
        <property type="entry name" value="LIPASE ROG1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12482">
        <property type="entry name" value="LIPASE ROG1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05057">
        <property type="entry name" value="DUF676"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="345"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="DUF676" evidence="4">
        <location>
            <begin position="15"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="DUF676" evidence="4">
        <location>
            <begin position="137"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="91"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="399"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="435"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="91"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="416"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="438"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0024806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="536" mass="60838" checksum="35E8037B67DAEA60" modified="2023-09-13" version="1">MVPQIDTHTLTEAHQGVHLVVLHHGLWGNKGHVKFIAQQFKKRFGNRILVYRAESNESSLTYDGIDICGQRAVEEISKVIHVIEEGGDISELRGQKKNKSKDSKKNTRSPNSSANSTPDQSNISCRNNSHEDISVTSTSNNTPKKVTQFSYIGYSLGGLIGRFVVGLMDMEKFFDPVDEGGRGIEPFYFVTMATPHLGIRQPPKSTWSKMYNYVSSRMLSRSGEQMHMIDDYVDKKPLLLVMTEPDSIFIKALQRFKRRAVYCNIRNDRSVPFWTASFSDADPFHELEAMEIQYHSGYSSVIESFEHYDTETLTRLKNEREESLKSLSFAKRTSKRISSMPWKKYAFFGILGPFLIPLWIIFASTTISYQGISSRKRTKHMVAASKVLQRIRHLSSTTKLDRYRDDDDNEDNNNSEENRSTDKDTKEQDVVVTVVNDSSASPSSSSTTLSDGEETTTVVSYSFPDLKSIRPLPLLPVQIEASRNLNKLEWKKNIIHIEALNAHASIVVREKRFMHDGGVAAVQHAVDMFKEDGEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MCH9</accession>
    <name>A0A9P6MCH9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_008865</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004969">
        <property type="protein sequence ID" value="KAF9991820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MCH9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9991820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="201" mass="22293" checksum="BC0F8095D7055EDF" modified="2023-09-13" version="1" fragment="single">TENIFVSKEVKDPALSEGIANAYHEHGTLLDDLGRHDKAKKSHSKAEKWGYVDRVGRDTGSSHPLAKSDTVRRSLLPTAALPAAPIVAVAMYQDSSKADVAQLNHQDHVLHATPAKDGMQTQQKIFDQNVTPPIAKYALPKPDERITSTPQLAYCLSLLHPSMISKEELDQNECDWLQDGTIDLDEKERLQTMATDLIRAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MD83</accession>
    <name>A0A9P6MD83_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_008368</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004505">
        <property type="protein sequence ID" value="KAF9992898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MD83"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005162">
        <property type="entry name" value="Retrotrans_gag_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33223">
        <property type="entry name" value="CCHC-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33223:SF6">
        <property type="entry name" value="CCHC-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03732">
        <property type="entry name" value="Retrotrans_gag"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="231"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="236"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="248"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9992898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="260" mass="30209" checksum="703E74A604575962" modified="2023-09-13" version="1">MSQIIALDTFLKNIQSCSKFHGRPDEDFCLWIDELEEIFAILSTPSARRVQGARLLLRDNARLWVKDYTSPTEDDDAWIHFKTGLTGRFDSPNKKYFARTRLWQLKQRGSVTKYITEFETLRAKIDDINEGEAIQAFLNGLKPKLQEHFAGHPIYHQDLSMIKQIAESLDNVQYRNRNMFGAPRPFSYQQRPPIPDPMAMEIDALDVQRQPRSPRPRDLKQQQIDFANRACFHCHQPGHQARQCPTKPKNKPHSGKAQSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MD97</accession>
    <name>A0A9P6MD97_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008275</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004435">
        <property type="protein sequence ID" value="KAF9993105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MD97"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9993105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="145" mass="16205" checksum="4718F381F01801C2" modified="2023-09-13" version="1" fragment="single">MDTATLQRIAQWEQTYAKGNKKPITTREYPPIRPRKDIVLQDVKPLPLIKKGSQSEQTGGVSPKVEPAEKNITALASPSIDNNASKAPKEAPTRKAYYESWDKFDVDRALEDIDTKEVNSKPFSENVPSKQAKKADVKATPKLQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ME49</accession>
    <name>A0A9P6ME49_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_007955</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004181">
        <property type="protein sequence ID" value="KAF9993998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ME49"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF309">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14510)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9993998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="125" mass="13952" checksum="D1BD7FFEB1BB49F5" modified="2023-09-13" version="1" fragment="single">MKEILDATPKNLISKVFLEEKVFQTWYDGRSVLIGDESEKLEVNSIVLCRGLNPLACHKLLPGAGQGAVMAMKDAVVIANCIYNMKDLSDESIKSAFASYYRQRYPESENVIKTSSIFTKVMCGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MEI1</accession>
    <name>A0A9P6MEI1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_007764</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004027">
        <property type="protein sequence ID" value="KAF9994615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MEI1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9994615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="290" mass="32981" checksum="F14AD44FDDC02D47" modified="2023-09-13" version="1">MPTKSKTGSVVSSFISRLQEMGHLEVSQEPDSEKLKNVKEYTPCYVVRSVASQLSVELKRHYRYGAKKLSEIVQDMIKKERVASDQEVDLTSQEPAIQLFVRSNATAGRSWCLSPLSSEEHGFLTFTEIDLAAFLHKRDDMHPSLKKLIGNEGMQRRLTQVELTRDQLQFETPGVLIQRLIAPVDPRTPTGDRLCGRQKKKASIAASVEIARPHEIQNHINDLRRNGFDPNAYNKKGYYLRGSIKTDGYNLQLLAYKLRELHSVKYKRYPAELLPDRLTTTTAGTSDYLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MF19</accession>
    <name>A0A9P6MF19_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007312</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003719">
        <property type="protein sequence ID" value="KAF9996211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MF19"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="41"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9996211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="63" mass="6468" checksum="A1121370F0FC3FB3" modified="2023-09-13" version="1" fragment="single">MTTAVVSNLEDDVTEENVSTATTLAADGTNTEGSVTGADPANTINTANTASTDSDDWANMMQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MHS9</accession>
    <name>A0A9P6MHS9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006173</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003030">
        <property type="protein sequence ID" value="KAG0001523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MHS9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="225"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="300"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="397"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="403"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="437"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="465"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="509"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="539"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="564"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="573"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0001523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="573" mass="62837" checksum="80BDE2969146D86D" modified="2023-09-13" version="1" fragment="single">MSYSLSTSFAYAPDVVDFDAMNITETFPEASSFSFEMSGSYNHSYSDSISGIPAAQQALWDDGQLSFHHTINSSRVFGHSSALSSLNNSANNSMSIGHPPSRHLLAPPPQFHHRSLAQHHSSPLKGEYPYTDSENVSEGNSSHPYDEFEESSLQNSWIDYTKDQNGLMLLNDKEHQDEQHLLFLQDIGSSANVSHGDSISLFAKLADESNLSCDLFKEELDIDETRDQSRLQEQLAGSSDNPPLRTNTPGSLNNNGKAIGNEIFDKEFLASLKAPLVQHPPPPLPSSNRNILDGLHVIPAPSFDDQDTRKLTQSNSEQKGGNEEYKRALKDFQDSLKVADPIKTPHKFAPLPLPIFWNEPKIRPRGLPSFNLADYKDKAKTSVTAKSTNPLVNAVASADKQESYSSSPTTTYSVPDSSNPSAFSSAGEFLPTDIKSKTSPTPKTPTASSYLDNTNNSQYDREVGAQQQKQTSSPTTERTKKSTISNPHLAFDPTIPPPERADESKSTKGRSTLQQMTKNNVQQDDLEDEDLGTVRRSAPPSTGSERQGSISGASAPAMSPRIPVTRKRPSLRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MHV1</accession>
    <name>A0A9P6MHV1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006433</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003179">
        <property type="protein sequence ID" value="KAG0000049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MHV1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0000049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="86" mass="9480" checksum="947442674C25DAB4" modified="2023-09-13" version="1" fragment="single">MSSMKRSRNAAGLVLLEAVEWGVDAPNWDCNDEEEDAVAGDSYMEREEGEEEEEEGEGEEEGEEVDEDTDEDNGDGDADEECDVEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MJM8</accession>
    <name>A0A9P6MJM8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">G patch domain-containing protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">GPATCH4</name>
        <name evidence="3" type="ORF">BGZ80_005459</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002691">
        <property type="protein sequence ID" value="KAG0005368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MJM8"/>
    <dbReference type="OrthoDB" id="29523at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050656">
        <property type="entry name" value="PINX1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23149">
        <property type="entry name" value="G PATCH DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23149:SF9">
        <property type="entry name" value="G PATCH DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01585">
        <property type="entry name" value="G-patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00443">
        <property type="entry name" value="G_patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G-patch" evidence="2">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="13"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="104"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="269"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="279"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="299"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0005368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="353" mass="39625" checksum="A730FBBAE422690B" modified="2023-09-13" version="1">MSFAEKQLAKFGWKSGDGLGKNKDGIRKSISVVKKNDTKGLGGKLDKWDFAWWDHVFNKSASNIQVNKDESGEVKVEKQGSTNIQKSRMGIISTSRPAGPSQPPQSDTSSPSMSSTSTMSSMAPRDEYADEDEKPAPVAKSGPSWLFGFVKASASSTVAEESKRTNQEFRSSSDSFVARAGAGYDELKASEADEYRDYTIKVSDQELFEACEGRTARKGARGEQPGKLGRVMKELLLDDNSETSSTKDSVNGKEKSEKKEKKEKKEKKEKKDEIDRKEKKEKKEKKEKSSKKEKKDKKEKKEKSEKKEKKDKTTSSSDKKSKKEKKPKADKEKSKKRKMDEDEPRASKKSKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MJZ3</accession>
    <name>A0A9P6MJZ3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Elicitin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005369</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002650">
        <property type="protein sequence ID" value="KAG0005977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MJZ3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040249203" description="Elicitin" evidence="1">
        <location>
            <begin position="26"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0005977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="173" mass="17767" checksum="73C8761FE5B0B116" modified="2023-09-13" version="1" fragment="single">MSATKSTMMMAILALFLCMTSTVAADLYSPGNPFNCTAFASNCQALTTSLYAGKNSTYQGPSYQCTNSSNLAAVQTLCAEKVLCLATFLVETDVNSTVTPTTTTSAAAATPTGNSTTNSTTSAISLALQYSFTSVDVTSQLLAMYDTSKCSAAVVQVATSFGALAVIATVVSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MK42</accession>
    <name>A0A9P6MK42_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">[acyl-carrier-protein] S-malonyltransferase</fullName>
            <ecNumber evidence="2">2.3.1.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_005443</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>holo-[ACP] + malonyl-CoA = malonyl-[ACP] + CoA</text>
            <dbReference type="Rhea" id="RHEA:41792"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="EC" id="2.3.1.39"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the FabD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.39" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010002685">
        <property type="protein sequence ID" value="KAG0005444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MK42"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004314">
        <property type="term" value="F:[acyl-carrier-protein] S-malonyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.250">
        <property type="entry name" value="Malonyl-CoA ACP transacylase, ACP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050858">
        <property type="entry name" value="Mal-CoA-ACP_Trans/PKS_FabD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024925">
        <property type="entry name" value="Malonyl_CoA-ACP_transAc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42681">
        <property type="entry name" value="MALONYL-COA-ACYL CARRIER PROTEIN TRANSACYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42681:SF1">
        <property type="entry name" value="MALONYL-COA-ACYL CARRIER PROTEIN TRANSACYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000446">
        <property type="entry name" value="Mct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Malonyl-CoA:ACP transacylase (MAT)" evidence="6">
        <location>
            <begin position="1"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0005444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="311" mass="34004" checksum="90006E4DF36815A7" modified="2023-09-13" version="1" fragment="single">QGSQFVGMGKDLYDTYAVARQVVDEADDALEGKLKHVMFEGSQEDLTRTENAQPAILTTSIAMLRVLEKERGFKIEESCKHALGHSLGEYSALVATKAVALRDAVKLVRLRGEAMTKAVTNIGTTAMSALVVRPAKLEALIKAMGEIEATLPRGEMAQISNINSSFQVVISGTVRGVDHASRVLQAQKIAARAVDLPVSAPFHCDLMQPAADVMKEALKTVKFEKPIIDVISNVTAKPIAKVEDISDLLVTQVTRTVQWHASIGYLRDKENVHDYISLGPGKVLANLLRKEYPLDFVKIVTTAEDIQQWTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMM1</accession>
    <name>A0A9P6MMM1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Zinc finger protein ZIC 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ZIC1</name>
        <name evidence="11" type="ORF">BGZ80_003972</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002085">
        <property type="protein sequence ID" value="KAG0008004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMM1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000125">
        <property type="entry name" value="Putative zinc finger protein 143"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043359">
        <property type="entry name" value="GLI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056436">
        <property type="entry name" value="Znf-C2H2_ZIC1-5/GLI1-3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45718">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45718:SF4">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23561">
        <property type="entry name" value="zf-C2H2_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="256"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="289"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="167"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="372"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="622"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="98"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="406"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="424"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="469"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="523"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="630"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="656"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="674"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="688"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="716"/>
            <end position="732"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0008004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="767" mass="87250" checksum="1D1AEBB5D954B141" modified="2023-09-13" version="1">MRDNRGGEMRTEMRSDARSEVRDVRDVRDMNNNTAQEVTSITELQTMLARFWDAHSRQFREIESSLTGQLSTLIQKNGFLCQKIENLQRVNTDLEYKFSITTSELERARREYSELQAKYELRNANYKDLKDVCYQLDAQLSKKNGTSPDESLMSRIDLASADRKKRRLSVDLTEGDSDNAFSPYEETEPTPGSLVAPAMRPIMPLTGPRPSSPPSGGTTQSTWTCLWKNCNQVFGALDWLVSHVEEHHIGLGKSQYTCEWENCVVKQKPFHKHHQVIRHMRTHTGEKPFVCNVEGCGKKFARSDSLLEHSRKHNGTPVDYYRMMEMSSQREQDAKHLNGLMLQMDTIQEHQPQRSYNDANHNSASDNVENGIASEQMTGGPGASSRPITPSHEQRSSEQQQHQQQYPGSSASQSGPPEPIELDSAEHEHGHSQDRSNRDPNPSAPREGSIYGSAALSQRDRLRPDVTTHSSQHGSYHPSQPQHQHQHRQQYPQSMSRDQSDIRPLHRGRGHAHTSSLGLSRMDIQDLPRVRESGHSHSRSMDYGRLDSRGPFHPMHSEMGHSQTPSLDYSRIDMSAYQRKDRGHSHTPSLEMPPIPGQQMHRMDERRPIHAPHGYIPSDEMRHQHHLQQQHHQQQQQQQQQQQQQQQHQAAQQAQFHGSQPQKASYTHSSHQRHPQDQERVHHDQNGQQQQQQQQQSSTKQQPGEIAADTVAQEQTDSPISSPTPRTPQSSTQEEPMTGGLTGAPELCVRSSVGPMEEDNKNVVAVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNJ8</accession>
    <name>A0A9P6MNJ8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Galactose oxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_003806</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002024">
        <property type="protein sequence ID" value="KAG0008147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNJ8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093:SF18">
        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="346"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="383"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="439"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="476"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="387"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="397"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="441"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="476"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0008147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="621" mass="68302" checksum="6BCEE600317F5D3A" modified="2023-09-13" version="1">MAYATVDERTLYIQGGENVFTNFNQLYSLDLTTNWNTSSPPWKALSMRLAPKDFEDGMVVSDDNNALIVWGYHTGISTYNITSDSWSIVTKTQPASIHPTVGKRIVADPRTGIIYKLASKSSLKKDPQIFVAYNPATNTTQLLTLPPVLAATQIDYHSLVWSTQRNSILLYGGYFDPTNQFNTEFYEYVPDNNNWGVIASIGDIPPLRSGHCMIPAYNGTKMVLFGGQDLVGQAFSSIYIYDITTLTWTRGNDINSTMNRNNMACSVAGDNFVAWGGNQAGDYPAILSTPAIYNLKESQWVSQYNVSFPTTISAPGTITGTVTGTAPVTNTAITSPMDFSSGNRSLTAPIVGGTISGVFVLSIIGYFIHRRSKLVKGYHEGTTTTELESRQVHTDTRPSSSETPLGTSPIEGASLSVQPPLVEQPSLYQTSPYQASTYQLSSYQSSPGESSGTNSMDPQPLHEQHHIPVASLSPYITHTESPQSSPGHHYKTDSPLLVQSTPVPSAPQMPWNSQAMQEPMGAQLDSGYDNDKPLPVEMTPVPSAPEMPQSLELTQEPMEIQLNPDNNHTPLEQQVALIRLQCDLQFQRQQQYLEQLRIEQQAHLELLQKQIADSKRDASTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNL7</accession>
    <name>A0A9P6MNL7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">PKH3</name>
        <name evidence="13" type="ORF">BGZ80_003782</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PDPK1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010002016">
        <property type="protein sequence ID" value="KAG0008164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNL7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05581">
        <property type="entry name" value="STKc_PDK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000163">
        <property type="entry name" value="3-phosphoinositide-dependent protein kinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000191">
        <property type="entry name" value="3-phosphoinositide-dependent protein kinase 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039046">
        <property type="entry name" value="PDPK1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050236">
        <property type="entry name" value="Ser_Thr_kinase_AGC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356:SF163">
        <property type="entry name" value="3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="79"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="28"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="396"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="28"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="49"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="401"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="430"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="458"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="483"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="496"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0008164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="549" mass="59123" checksum="166C6E816070A06E" modified="2023-09-13" version="1" fragment="single">MSVPMSDPHQDPVSASLSLPLSLSDESTLGIPASTSTSTTTPPTPVPAPAVVSPSTSSTSKINDASVAIPVRKRTLADYKLGRTLGEGSYSTVVAAVDQSNKRDYAIKVLDKRHIIREKKVKYVNIEKNTLYKLDHPGVVKLYSTFQDSSSLYYVLELCQHGELLTFIKKLGSFDENCTRFYAAQILTAVEYVHNQGVIHRDLKPENILLDNRMYIKLTDFGTAKMLEPSEDGTESDRANSFVGTAEYVSPELLTEKAACKSSDLWALGCIIYQLLAGRPPFKGSNEYQTFQKIVKLEYSFPAGFPKTAMDLVSRLLVHDPNERLGANNTIDKLKQHPFFDGVDWDNLWTQPAPKLMPYLPPTPTHNTEPLRSDHDACLWNVNRAGETLMAVDPFRELGDSGSSVGNSEQNSMSGSDEGLHKGTGALEATKSSNTAAAPSTAVATGTTSRSLPELADSTGNLPQSNSKAGPGPSPLQGVIPKSTSASAAISSSATRDSPVSNGHTKTKSSSKNAIVALFSSSPKNPSGKKLLGKNSKHDQLEALQDGAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MP82</accession>
    <name>A0A9P6MP82_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Autophagy-related protein 14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_003462</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATG14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001918">
        <property type="protein sequence ID" value="KAG0008422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MP82"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000323">
        <property type="term" value="C:lytic vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032991">
        <property type="term" value="C:protein-containing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035493">
        <property type="term" value="P:SNARE complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018791">
        <property type="entry name" value="UV_resistance/autophagy_Atg14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15157:SF13">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15157">
        <property type="entry name" value="UV RADIATION RESISTANCE-ASSOCIATED GENE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10186">
        <property type="entry name" value="ATG14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="448"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="588"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="67"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="455"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="473"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="495"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="507"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0008422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="613" mass="67791" checksum="0DFB702D81DF7067" modified="2023-09-13" version="1">MRTMCPLLVCTNTTDHLLKHWEQLDVITTEKDKLAAQANQVLSPKIKRYQMCLAQRAMAVEHAAAILEERKSMLAELEQDRQKLIRLRTALHQRKETLKLSKARLKVSEMNGPPKITSSIERIMKDWAIAHQKLGHSRRVLVAELVTLFDLKCVPERRRNSENYNLTQSAISTATTVVGAAPGSPNAKDGRQKTKLRVRDYLEEDSWNEYLIVGRPLPTGFFENYDRDEINTTIENVIHMMKLVACYLGIKLPFDTFIRQSRYYIQAALSSSSKRAPLFLSDSNIMLFAAGLGYLNYNIAYLCHSQGVHITLANAANTLENLLACCEATNLGRYTNYAAVMTKRPENATEASSATDEIAPLSPVSYEGDYENIKMGSKKAVERNEHLLWCPGQDPFDLNVIDLIALIRSRREEESPVWGGVHLQDAVAANLETLEDDYFMQDDHEEEDGMYDYNTHGSESGSTLNTPSGSGGSVLSRTDSSSTLSSQHQRRPPHPSRDRRQSHSESEQPQLHSRDSNPTPTGHAQPENWTFLDVDISRVPSSVSKGSGLLSGRGWPDISVLKKVGSAVGGAAVGFVNGASNVAAVATAKGSRQGSSRYSSGDSSYSTISSSAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQ33</accession>
    <name>A0A9P6MQ33_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_002583</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001640">
        <property type="protein sequence ID" value="KAG0009259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQ33"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0009259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="161" mass="18294" checksum="08D29E14C6604BC5" modified="2023-09-13" version="1" fragment="single">MLQPDFGTEINRKYMAFVEFRNIQYALSVHQKTLGSPQRQGQSHIEAYSWPFGLQKKQDLDEEDSETDFKAIDFDEVNFGDSSSNESDFDGVGLDQIFLDGFYNIENNNESESAPRVEMDLDADFGLMGEIDFATASLLTKAIEALERKALKSMTLERKVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQI3</accession>
    <name>A0A9P6MQI3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GRAM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_002240</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001549">
        <property type="protein sequence ID" value="KAG0009584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQI3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006915">
        <property type="term" value="P:apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037847">
        <property type="entry name" value="GRAMDC4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37402">
        <property type="entry name" value="GRAM DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37402:SF1">
        <property type="entry name" value="GRAM DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="233"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="356"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="478"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="483"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0009584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="596" mass="67855" checksum="3C16D1A796CB0F53" modified="2023-09-13" version="1">MSNPDYNSIPELPPPLPARRPTVPTVTEDAKPYYLASRPSAEENNEIEDLNSPPPLPAGQRIPTIVTPQTDTETAGSPAQKMPSYPDGSLSPKSKSIAPSTSGLTTATAHTAHTALSGKTEEEVTFEFDRHVQEIRRRRTVARRPPPPDKDDYTRIEDESGKRVLDVGLYIQANVTYFIESLARDDKVKKIEPLQWKRMRGLLSRLYDTSNPVQSLGLYVERVMLWKNPPETFIWFTVYFTLWLYKLWLPAFISLFVIKILNNRYGFLGDFKEKLNVPASLSDRLNVANDNDVKRKSKIHSQLRDLIHSKDLTDWISQMTKIWGPYCQALLEENVNYLERVKNLFRWERPEQTWRVVALLSFYIFVSTFFQFLVLPAIGYAIGVEYFILLPMQHYYPRYSHLFSPVEWILWGVPTNAELAVEMLTRQREGAEGIDDTFEPTAHEEEVEQDSASVAGLSPASKIKHEYQKRIRGMSLSGTSVMSESSSADNADSSAQDKNEFHCTMRGKPGKLVITEEAIMFRSARLLGRETEVQISWGDIDSVKKSRTMNVGLWSMPGIDVTDIDGKVTVFQNVVKRDEAFRKMVLTSGKKWSSVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQK5</accession>
    <name>A0A9P6MQK5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HTH APSES-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_001845</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001431">
        <property type="protein sequence ID" value="KAG0010035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.260.10">
        <property type="entry name" value="Transcription regulator HTH, APSES-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036887">
        <property type="entry name" value="HTH_APSES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003163">
        <property type="entry name" value="Tscrpt_reg_HTH_APSES-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057511">
        <property type="entry name" value="WH_GDS1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34491">
        <property type="entry name" value="A-TYPE INCLUSION PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34491:SF156">
        <property type="entry name" value="KINESIN MOTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25318">
        <property type="entry name" value="WHD_GDS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54616">
        <property type="entry name" value="DNA-binding domain of Mlu1-box binding protein MBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51299">
        <property type="entry name" value="HTH_APSES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH APSES-type" evidence="3">
        <location>
            <begin position="1017"/>
            <end position="1125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="96"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="322"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="378"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="605"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="852"/>
            <end position="997"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1469"/>
            <end position="1554"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1411"/>
            <end position="1440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="104"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="174"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="232"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="280"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="334"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="378"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="411"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="609"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="634"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="653"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="687"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="892"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="912"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="948"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="968"/>
            <end position="981"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1488"/>
            <end position="1497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1505"/>
            <end position="1516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1532"/>
            <end position="1554"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0010035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1554" mass="166869" checksum="4F685EEA547FA6DC" modified="2023-09-13" version="1">MPMPTQPQPSGRHTISIGGGASSGLNNNGIILSNSSQYEDELPASSKAPLKYALKDIHPDDSKDKVFAAILKALLYLRNKPSSPKELANCIMKNKYTMLGVGSDNEDEEEEDGGAREDDDDDDDPEGDQDDDDDDDDDDDGEMSGDSTERRQKRRRQHLYQQHQHLNPDSMLHKANRSAMRKRKKVKTWSVTNRPTVKRFKSKHPLIGSFKASTPTNIHPSKWRPPNNQEYSESEDAEDESAEEEDEQDEDDDVFGKDDLVLMDLQMPDVEKDARLPTPRSLSNFSTPSPHSSASNAVNPNGSLSVAAGMHGLLNATKILSFDSKKSPPRPGSHSATARSNMGGVASSSVSAELMNESSDDEQDFSDYHEEMMHGDFEDLEDDRKTEDRKPSLPTQPQAMAVPIPSVRNATTSSSFTTGGTPISPFSNLATTPNSNSFLLGMSPRSRKMAMGGSMSGSMSGLLLPPDSLLLSPRSSSIFDSDFSSNLLVDYSQDMSSPKEHYYVPLMELNNPESMPVSELDRLLSSSAGGTFFPSLSRKVSISGWSNINSKHLGLRQSSLRNTANGILQNAANSSLNASTSPYLGSSNTGTFALASPVLPGSNGLKATGVSSTTPSATEQQEKTQTSVLITPASSKPVSLSDSTSSLQPSKTPTSPTSAGKSTENPAPAADSSINTKDDVNMQGAQEEGEEQDDETESELEDEDQTQSKMSSEPPKSLVREAVYANLNVYETVMPGTDLRLMRVAGVVAPPNPNMNGRGVVIQKKVIPALNNDQHAGFVNAAMLRLAARTIIGDGQFDINQEPTTLYIVLEGPIEVRGAWVGLARARELCHEYRLDLLPGIAQMLQDDPVKVACPSESRGSSEKKKGLKRNRQKQGAEQHLSHTSALINKDNASKPEDADRRNSTVSNLSTADKRKSHAADDDTTPFVNFEELEDRPKKAQDDDVEMASSTLQTMALSSQGVDGVDTQSSAGGQIGSSGAADSNQRATEGVVAQNGAREPEANQLWIPTTNPVVPSIHLTVIDNVALFTTKLVNPGAEYRLLRRADNGYVNATTLLLAGGVETEQERSIVLSLELGRVRVRKPGSQLFGTWIPLARARALAATCSLHHKLGPFLNDNLDTYFPSPLPIPNQRVTPSVVTATASALMNHQAVTSARMRTVSLSALRSSTSPPNGLARNGALSHQLSRGMMGNAGAAHLQQVLAQQGHVPGATLSSMVMLNGNQVETQSGSSTSAAASTTATTNLTPATVTQTGATPASTTVIISGANAPATAGTLPGAVSLTQSTLNAAANTNLLQALSQVSQGVQLNAAAQIRPLQGGFMPRVEPHTGRPILPMINETVSAVPGQSVIPVKDYQDPDDDTESDDDVEGVRQKMKQLRAQQLEEAEKNFLKQTTPAERVIGQVNSGQKTPSLAQQQQQIQQQQQLLQHQQLQQQLQAHQQQQLLKQQLQLQQQQQLVQQQILLNQQQQAAQKAQASPTRPSTRGGKTAPRSSNRAQNSESDDEGSENQQRIALSPSTGGKKGSGIGGAKPMAIDDEVDSDEDIDIGGSDGDDDLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQZ4</accession>
    <name>A0A9P6MQZ4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Peroxidase</fullName>
            <ecNumber evidence="13">1.11.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">CCP1_1</name>
        <name evidence="16" type="ORF">BGZ80_001630</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Destroys radicals which are normally produced within the cells and which are toxic to biological systems.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>2 Fe(II)-[cytochrome c] + H2O2 + 2 H(+) = 2 Fe(III)-[cytochrome c] + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:16581"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="1.11.1.5"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion intermembrane space</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peroxidase family. Cytochrome c peroxidase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.-" evidence="13"/>
    <dbReference type="EMBL" id="JAAAID010001377">
        <property type="protein sequence ID" value="KAG0010266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQZ4"/>
    <dbReference type="OrthoDB" id="2859658at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004130">
        <property type="term" value="F:cytochrome-c peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000302">
        <property type="term" value="P:response to reactive oxygen species"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00691">
        <property type="entry name" value="ascorbate_peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.420.10:FF:000009">
        <property type="entry name" value="Ascorbate peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.520.10:FF:000005">
        <property type="entry name" value="Cytochrome c peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044831">
        <property type="entry name" value="Ccp1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002207">
        <property type="entry name" value="Peroxidase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019794">
        <property type="entry name" value="Peroxidases_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019793">
        <property type="entry name" value="Peroxidases_heam-ligand_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356:SF58">
        <property type="entry name" value="CYTOCHROME C PEROXIDASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356">
        <property type="entry name" value="THYLAKOID LUMENAL 29 KDA PROTEIN, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00459">
        <property type="entry name" value="ASPEROXIDASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00458">
        <property type="entry name" value="PEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00435">
        <property type="entry name" value="PEROXIDASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00436">
        <property type="entry name" value="PEROXIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0349">Heme</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5 13 16" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="15">
        <location>
            <begin position="102"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="210"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU363051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0010266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="371" mass="40971" checksum="C6ACD27CEFA939C1" modified="2023-09-13" version="1">MASTARFLLRTSSLSTFARRATVAAAVAPRFTAVRTFASHPPQRPTGVKASSGGMSPLVIAVLAAGAGAAGYHYYVQGSTLPQIASTATSGGEEKKPLDYQKVYNAIAELLEDDNYDDGSYGPIFLRLAWHSSGTYDKNAGNGGSSYATMRFKPESSSSANAGLIIARERLHRVKDKFPDISYGDLWTLAGVCAVQEMGGPIIKWRSGRIDGEEKDCPPEGRLPDGGRADPQHSRDIFYKMGFNDQEIVALLGAHALGRCHRDRSGFDGPWTASPTVFTNSYFTELLGRTWVERKWSGPKQFEDKETKSLMMLPADMAMLKDKEFKKWVEIYAKDEKKFFEDFAKAAEKLFELGCKFDENSKIYEFMPTNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MR89</accession>
    <name>A0A9P6MR89_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_001784</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001414">
        <property type="protein sequence ID" value="KAG0010107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MR89"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="164"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="66"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="256"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="66"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="106"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0010107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="338" mass="37162" checksum="C43F2438EED4F7A3" modified="2023-09-13" version="1">MAAAAAIATANHTLSINTTSSMTSAIRNRHRTNSIHLQHNLSNMVQHQQRRQSIYELRRASVSSPTTATAAANATSNSGSATSTAASLPSSSLPSSTSLPSPSSAYTQQRQSSAATPRHHRVAPVKVTPFPSMTFYGLPSFSIAVLLMAFVLGQVDTLWSKISCLTGSMVFYVLCWIFVVQIIAPSAQDYQQQRDAYFQDQAAAAAAATVAMVSMITPTGMTTTSSPTSAYNNNHEHAFNGMSISNAMEYEFDPNAALHQQQLQRERRQLLQQQQQQQQQQQQQQEQQQQQSSTSSAGIPFCSVAQWVMSNQYAQNLVRRFTDLVEIMDDYSETLGHW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRA4</accession>
    <name>A0A9P6MRA4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001092</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001243">
        <property type="protein sequence ID" value="KAG0010914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRA4"/>
    <dbReference type="OrthoDB" id="2399191at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040431540" evidence="1">
        <location>
            <begin position="22"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0010914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="398" mass="42780" checksum="2F9D4E1578D9998F" modified="2023-09-13" version="1">MVKLSLILLSLSATLLAVTEAKTDPGACFLHVPKDPLSAKGLATPYILKKGNCDQTNPDQQVFVEATVFDPKTKTFAVYHPLVINEGTKPAIAPVVPKLPKGAVVGLWFGANSNSVTLTGNIENCVNGLSSTNVFGQVAFCNAEHFFKVVHAADKYGKAVVIPQLGTDVHGKACPTTRHFGIIDQDQSDNVITTYLQKGNRFAQNTKHNRKKLKKAVVLSNGSDNALLADFVDPVIGCKPFKARSLMEDGVVLGSMALNELQATRQGAPVALIPAADPMVLSNGKPCIRKLNAYRKGVDQKLAHHLSEASTKAYCTNFDKIAPAYIKSISAQLQKGASPTPDAANNLLTFMGQRYAASWTNLGCDKVLKKTSAITVTTNEKGVATKVHFNQSMRIHRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRH4</accession>
    <name>A0A9P6MRH4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mediator of RNA polymerase II transcription subunit 19</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Mediator complex subunit 19</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_001255</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Mediator complex subunit 19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001283">
        <property type="protein sequence ID" value="KAG0010697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRH4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070847">
        <property type="term" value="C:core mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013942">
        <property type="entry name" value="Mediator_Med19_fun"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28270">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28270:SF1">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0010">Activator</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="126"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="177"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="201"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="215"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="229"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="253"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0010697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="269" mass="29896" checksum="DD6598595CC5B375" modified="2023-09-13" version="1">MAENEDTATNAQPNSPKLYYIKEARAKAVPQQLTGSHDLMTTFNLLPLYNKYVKQKFENNEDVPPIEPTYFPFISDLPGKNVIRPGNYIRALLEAPEKSYGPIHAFPSSTIRDGFSLRPGPVTGFDSSVLGTEEDTANRNSLKIPAARGAVTGDSHNSGYGDSNSVPPGSSPAQYGHSHHHSHLHPGHTHHGSKSSTSSPHVDRAERGDGDGSREHKHKKKKKKRKHEHDHDHTHHEGEGDSEHRKKKKRKKEREGHGEYGEHGDVDIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRJ7</accession>
    <name>A0A9P6MRJ7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_001397</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001315">
        <property type="protein sequence ID" value="KAG0010538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRJ7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="268"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="323"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="374"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="417"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="331"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="374"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="417"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="455"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="489"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0010538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="536" mass="56703" checksum="C40FAC10B7F963D1" modified="2023-09-13" version="1">MATARYLTSIPTTQPSCGELTLSNPTPQCNTNSTSGPMGCFVQPTGLYCAPLSTTRGFLYVIDDLSSNSTSSIDSTSATITTTQHYNPIPKLSTVNVTNISNSTLDISGQPVLTQGPALLGQECVGIPLPPETNPVWSFLVTMANKRLNDTLGVSPGAGAGSEILSMRSDCEPNTYCDFTQSQSQPQSQQVGVCKEQLPNYHTCDSYIQCISLRCDMETESSKNLHRRRDSNKKRSAGMVCLPSIVAGDNGTLVGGGSSSDDNNRSSFPMWTVALIVVVIVGGAILTFVLVRRRNNKMKKRAAAAAGGGLPHQIRPNMERLRERERERTMMSISSNSTRVSTTSDRDNNYNNNNNNSDSKIILPKIITTFSDQSTLASSSSPTSRSIKHSPTSSTLSGSAPPSPSILSIFSLNSSPSSPISNSFSRRSSSGHSIPLSNDRPQEEDASPSPGLLCVSSTGSPPITTTNNNIPSRPNSGGSSLAPPPSSPNSPTVPISPISPISPISPVSPLSGSNYGGTSRLAGRNNSNHQAGYRKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRX7</accession>
    <name>A0A9P6MRX7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SF3 helicase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_000794</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001174">
        <property type="protein sequence ID" value="KAG0011291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRX7"/>
    <dbReference type="OrthoDB" id="2442727at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006500">
        <property type="entry name" value="Helicase_put_C_phage/plasmid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014015">
        <property type="entry name" value="Helicase_SF3_DNA-vir"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051620">
        <property type="entry name" value="ORF904-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01613">
        <property type="entry name" value="primase_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35372">
        <property type="entry name" value="ATP BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35372:SF2">
        <property type="entry name" value="SF3 HELICASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51206">
        <property type="entry name" value="SF3_HELICASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SF3 helicase" evidence="4">
        <location>
            <begin position="32"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0011291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="338" mass="38465" checksum="2BE45A0C67DAA5B6" modified="2023-09-13" version="1">MSRQLDVDYNGLESSTAMIDEFIGDLFNRDQGSIMYLQRLLGYGITGHTDSQIWCMFTGEGSNGKSLLASFLESLLEEWVVTAPHEIFFRGDQRAREGSHSTHLGTLRGARICIKEEAKPKDKLNAEILKVLTGGSRITMRAAHASSFETFDPMCLPILLCNHKPEVDVTDAAMMRRIVVVPFSNIYTLPDDPKRPFNPNNPHHRLRDPELKKKLLQEHARKQLLVWLVKGAVAWYKNKDLSSQPPAMLAAFQEYNDENDKLQQFINMNCEMGNTFYINAGLFREEFCKTMYASILQKTLVTLMAEKRLKFGSPRINGKTEKVYHGIRLVGSENCLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRZ6</accession>
    <name>A0A9P6MRZ6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">WD40 repeat-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_001100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001246">
        <property type="protein sequence ID" value="KAG0010898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRZ6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848:SF8">
        <property type="entry name" value="F-BOX AND WD REPEAT DOMAIN CONTAINING 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="14"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="56"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0010898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="232" mass="25251" checksum="B5AD7F7E0A371F74" modified="2023-09-13" version="1" fragment="single">RLWDVDTGECVHTLQGHSSTVQSVVYSPKGDRIASGSSDSTVRLWDVDTGECVHTLQGHSDTVQSVVYSPKGDRIASGSDDKSVKLWKVGARQCQTIISGFSSGVSSIALESDFGARCLATGSFDKSVRRWRITKEGVEHKAVLCWSSSHEVLTVHDLSFEDAQGLRSQEVYADQVRNPDVETPNPFRLAPVSPDVASILSQLNILLNVGAVEFYGHLQASFNRGSKALLEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSC5</accession>
    <name>A0A9P6MSC5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]</fullName>
            <ecNumber evidence="10">1.3.1.88</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">DUS1L</name>
        <name evidence="19" type="ORF">BGZ80_000458</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>5,6-dihydrouridine(16) in tRNA + NAD(+) = uridine(16) in tRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53380"/>
            <dbReference type="Rhea" id="RHEA-COMP:13543"/>
            <dbReference type="Rhea" id="RHEA-COMP:13544"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.88"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="14">
            <dbReference type="Rhea" id="RHEA:53382"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>5,6-dihydrouridine(16) in tRNA + NADP(+) = uridine(16) in tRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53376"/>
            <dbReference type="Rhea" id="RHEA-COMP:13543"/>
            <dbReference type="Rhea" id="RHEA-COMP:13544"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.88"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="12">
            <dbReference type="Rhea" id="RHEA:53378"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>5,6-dihydrouridine(17) in tRNA + NAD(+) = uridine(17) in tRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53372"/>
            <dbReference type="Rhea" id="RHEA-COMP:13541"/>
            <dbReference type="Rhea" id="RHEA-COMP:13542"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.88"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="11">
            <dbReference type="Rhea" id="RHEA:53374"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>5,6-dihydrouridine(17) in tRNA + NADP(+) = uridine(17) in tRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53368"/>
            <dbReference type="Rhea" id="RHEA-COMP:13541"/>
            <dbReference type="Rhea" id="RHEA-COMP:13542"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.88"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="16">
            <dbReference type="Rhea" id="RHEA:53370"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a 5,6-dihydrouridine in mRNA + NAD(+) = a uridine in mRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:69851"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:17789"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="13">
            <dbReference type="Rhea" id="RHEA:69853"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>a 5,6-dihydrouridine in mRNA + NADP(+) = a uridine in mRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:69855"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:17789"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="15">
            <dbReference type="Rhea" id="RHEA:69857"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the Dus family. Dus1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.88" evidence="10"/>
    <dbReference type="EMBL" id="JAAAID010001097">
        <property type="protein sequence ID" value="KAG0011728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSC5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017150">
        <property type="term" value="F:tRNA dihydrouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018517">
        <property type="entry name" value="tRNA_hU_synthase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11082">
        <property type="entry name" value="TRNA-DIHYDROURIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11082:SF5">
        <property type="entry name" value="TRNA-DIHYDROURIDINE(16_17) SYNTHASE [NAD(P)(+)]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01136">
        <property type="entry name" value="UPF0034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0288">FMN</keyword>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0521">NADP</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="DUS-like FMN-binding" evidence="18">
        <location>
            <begin position="1"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="270"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="406"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="295"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="419"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="19">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00038890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00049467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAG0011728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="429" mass="48485" checksum="B533713BCABE800D" modified="2023-09-13" version="1" fragment="single">FCANDPEHLLHAALLVAPYCDAVDINLGCPQHIARRGHYGSFLMEDWPLISSMISTLHKYLPIPVTAKIRVFPEAEKTVAYAKMVVEAGAQVLVVHGRLREMKGHLTGVADWEKIRLVQEAVGHLVPVIANGNILYHEDVERCLEKTGCAGVMSAEGNLYNPAIFTPNHPESWRLAEEYLTICDELDTKIAYTRGHLFKIFQPCLSIHTDLRTELGLTNSREAMWEVTRKLKERLIKDEEDSKQRGESFEGRVNDKGFPILPHWVAQPYFRQPMPPQDQKKSEGGGEAALTSTKRTAEASGHREDEEHGPIVKIKPSKNKKVKVAPSICNDAKCQNSFSPKCIYQMCKGCCRLHQRARDQFDCPSHPINSVRKDKQRLPRVDSQEAIGLVALEGMFVNPQDEEVVTHHDHGVQQEQEQPEQKQERCLIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MT02</accession>
    <name>A0A9P6MT02_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Aspartate aminotransferase, cytoplasmic</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">AAT2_1</name>
        <name evidence="8" type="ORF">BGZ80_000522</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001109">
        <property type="protein sequence ID" value="KAG0011655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MT02"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004069">
        <property type="term" value="F:L-aspartate:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006532">
        <property type="term" value="P:aspartate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000064">
        <property type="entry name" value="Aspartate aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000796">
        <property type="entry name" value="Asp_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006719">
        <property type="entry name" value="PRK09257.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11879">
        <property type="entry name" value="ASPARTATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11879:SF55">
        <property type="entry name" value="GLUTAMATE OXALOACETATE TRANSAMINASE 1, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00799">
        <property type="entry name" value="TRANSAMINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="7">
        <location>
            <begin position="36"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0011655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="382" mass="42199" checksum="A2D064B4DA14037E" modified="2023-09-13" version="1">MSSTSNHPAVRLQQISNHIATKKDTGMNKSADRILVEDDNLDHEYLPILGSNEFRFASAKLILGANSKAIAEGRVGAAQCISGTGAVYTGAHFLSKHYPIKGAACYISKPTWANHRAIFEGVGIPVLEYPYWDAATKGLDLKGMLSCMQSAPNGSIFLLHPCAHNPTGVDPTPEQWRQIADVMEAKGHFTFFDCAYQGFASGSLTKDAFSVRYFVDRGFELFVAQSFSKNFGLYSERAGNLTIVAKTPAVKNRIESQIAKAQRAVISNPPAYGSRIVSVVLNNEKLYSEWETNLASMANRIIDMRKALYDELVRLGTPGKWNHIVDQIGMFSFTGLTTPQVKVLKEKYHVYLTDNGRISMAGLNSQNVKYFAQAVDYVVRNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MT72</accession>
    <name>A0A9P6MT72_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Oligopeptide transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_011503</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000932">
        <property type="protein sequence ID" value="KAG0012802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MT72"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035673">
        <property type="term" value="F:oligopeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004648">
        <property type="entry name" value="Oligpept_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22601">
        <property type="entry name" value="ISP4 LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="5"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="51"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="80"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0012802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="134" mass="15682" checksum="F630CA767349CCE2" modified="2023-09-13" version="1">MYNAINYFFLIGFVLPIPFYYLKKYSGVAWMEYIHLPVMLSATGMMPPAQAYNYTNWLAMGFMFQFFARRYRPEWHLRFTYVLSSALDSGTAFCVLFAFFIFTNRNVAMPKWWGTRDDLCPLDGSPYIPVVPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTN7</accession>
    <name>A0A9P6MTN7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_000134</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001021">
        <property type="protein sequence ID" value="KAG0012202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTN7"/>
    <dbReference type="OrthoDB" id="10250354at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042407">
        <property type="term" value="P:cristae formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024586">
        <property type="entry name" value="DnaJ-like_C11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055225">
        <property type="entry name" value="DNAJC11-like_beta-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052243">
        <property type="entry name" value="Mito_inner_membrane_organizer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44157">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44157:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11875">
        <property type="entry name" value="DnaJ-like_C11_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22774">
        <property type="entry name" value="DNAJC11_beta-barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="5">
        <location>
            <begin position="36"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0012202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="596" mass="66586" checksum="D2F69410B4987B64" modified="2023-09-13" version="1">MDDPYEDRSMPADSTGNNYEPDDLHDLENMKPQEVDYYAVLNLSKAASEDEIKDSYKRLSRIFHPDKHSDPALKEAAETKFHIINKAFEVLSNPQLRTAYDEYGEEGLNTKWEVGHKVKTTHELREEYARLAREKREMELESLVRSRSDITINVNATRVFRNQEILSPFGGTAYARKNSGSILSALKRTEIMQLYMKNSFETQFGPRTQFIVAGQMTARSGMGGGNVVGTVRHAFSEKLSIELGSSLLKPRIGVFKGTYSIDPLTFITGTAQVRNFQGPAPLAMTFGRRITKGATGYMTYRTGEWAIGKWGPVLERRREFSSLALGVSSQGEDRSYQVEVQTGIMQSHLSLDHTWKLDRSTMIRVGGSLSTTAGINASIGGDRKVTEHTKVGLAVEVGLSGGVAFNIKVKRLGQSVTIPIVLAAEFNPKLAFWATVVPICVVTALDIGYVKPKRRKERAEKIQELRKVHADFIATQKKEAEEAVELLRESTIRKMRQEQEKDGLVILEAFYGNLNAAPELGLVVDVKIPIQALVNNSQLIMPAGHSKTHIMGFYDPCLGEKKQLRIKYEFQRRLHEVVVADLASVAAPVRSHLLAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTU0</accession>
    <name>A0A9P6MTU0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_000150</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001025">
        <property type="protein sequence ID" value="KAG0012173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTU0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0012173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="496" mass="55933" checksum="52EDE78169767B0D" modified="2023-09-13" version="1">MSAIDFFEFESFLYKHRKIASQEWIQVVVPIIEKINQKRAKLLRHEWNLKPQIRAKYWDNKRREEEKSSHLTAVQSEGRIQSIASVRSITDETIKGLAPNNLNIRRGKPMADGLGQELENTTRLAGPSIISSTSPLTLGDLETVGECTAQHLPAAEVTVQPDPSEPLIEESDEIAELHATLARSSHVTCEWKVNNDCVACRFQDYQRECINALDQKILKRVDVADVMALIGVFAPFIPTPRMTSVFGRMLDYLQTSVKFPAPHIDDLAIMEAVRQRLNGERDEACETIRSLDRKKRIMFETLLEKLPMKSDKTISEGTFVTNYVSPLIHGTLTFDDERVQVYFPNTECQTQKQQGIKADRPDIVIKFRGQEVLFGEVTGPAQAGHTAKNAWDLFRLARFGKAFLDQGNSVAPLLQIVYNNGSFMRLTIRTRGMFILKEIGAFEVPTKVAAIPTLAATIPTLLAARDDVHRILNGDMNTLKRSWGYGDIPDAKKRLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MU32</accession>
    <name>A0A9P6MU32_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_011511</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000934">
        <property type="protein sequence ID" value="KAG0012788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MU32"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34286">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34286:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0012788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="66" mass="7346" checksum="6A36B97E984C5B51" modified="2023-09-13" version="1">MAGGRYPYPKHVWSPSGGWWTQPTNWKSNTAVAVGITAAIVAGAWKYSAENEWAKEFRDGEVYGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUA1</accession>
    <name>A0A9P6MUA1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Proteasome activator subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BGZ80_011552</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus speckle</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the BLM10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000942">
        <property type="protein sequence ID" value="KAG0012734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016607">
        <property type="term" value="C:nuclear speck"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016504">
        <property type="term" value="F:peptidase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070628">
        <property type="term" value="F:proteasome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010499">
        <property type="term" value="P:proteasomal ubiquitin-independent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032430">
        <property type="entry name" value="Blm10_mid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055455">
        <property type="entry name" value="HEAT_PSME4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035309">
        <property type="entry name" value="PSME4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021843">
        <property type="entry name" value="PSME4_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32170">
        <property type="entry name" value="PROTEASOME ACTIVATOR COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32170:SF3">
        <property type="entry name" value="PROTEASOME ACTIVATOR COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23096">
        <property type="entry name" value="HEAT_PSME4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16507">
        <property type="entry name" value="HEAT_PSME4_mid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11919">
        <property type="entry name" value="PSME4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Proteasome activator Blm10 middle HEAT repeats region" evidence="11">
        <location>
            <begin position="255"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="domain" description="Proteasome activator complex subunit 4-like HEAT repeat-like" evidence="12">
        <location>
            <begin position="1083"/>
            <end position="1370"/>
        </location>
    </feature>
    <feature type="domain" description="Proteasome activator complex subunit 4 C-terminal" evidence="10">
        <location>
            <begin position="1671"/>
            <end position="1757"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="238"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF11919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF16507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF23096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0012734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1757" mass="200298" checksum="8300DB7A4846A61F" modified="2023-09-13" version="1">MEQPQSQWGDLSTALHNILPYGRDLSQEASNMLSNIISHMGICLQSEDWAPGVLYWAKQLKQYLDLKYTLPNETRVALARVFWELAVAPGMDATMIEVWAQYCRRLINKRMGKLVRLAEEAQRFFPPESSDEILEEFLPKITTCSLPESLKSMSYIRCFLPTDIESGKDPRDWMPALFRLWSMFAHSTEFDRCMMSIVGHVAQNNVGVKDMFTQDQIRTVFSAGLSALSLPVGKGQRTNNVDAEGGTSHRAISRNEESPKCKTPQELRLTPELNIKFVEAIRGVTFLMMFSKDLRAVAQTNKTLRFLAWIAPNLIIPGVLERAYPSLESLTETHRTTSVISAMTSLTIPLLNREHYPQGGKHLLPLLHLTVPGVDLNDPGKTWYTLLFVSAMISTVPIRDLTEMGSAGFQWGGMEMDMLDSEDVVDMELEDSNRKATTAEFEEWVMKLLRRAILMFENFPDMEQDAKKGTVESSLTGSISYCFEILFSQLSPKLYDMTTKLVIDLLESAPLTNAWKAMAAFISCWASGNRESAMKKVFHILDRKIRSELEHGASSVPSLAYSHMHRDDSLHYYQNLLRHLLLSADITGYREEIVSLANLMVEKCHDRRGYKLAAKVMVSALQNLLTTYTLSTRSHNSTLWDDEVFMTESHLHWGEMSEAGVDSLDWHIPSQEEINFAIALIEAFHVPALTRARELMITSQLESKQLSIELCKAITMIKAFVLGMVTLVEDDGDSPVSKPSLCEDGASVQPLKPIEVRYCLTDHNDPRTQKIRKIRAETGQLLHDLMQFFHTKREDDVENVKVLVKATRVYLTDHGADSKAYESSRKGYDFLKEMYQIPGDKKIYPRFMHARRATTFHCLRLKINSYGRAKTEMHDALILSLTDLSLSQYADVRKKAQHALLRAVKCYQGAKNLVIPILLKALESSNTDYERMKGALYSLSSKALMLPCLRDWRFVPEYVLRICTAHHADKPSIQILIRKCFVEYIINSTNPSFKVLVSSDLSSAIERFNDAHSLKFDSELISHATIKTKNRRLNNIKAYDNLLVSLTELANDGSLHWRYQTMVMSFMELYVRPEIPTSLEMVQFEAKSLLSDMPTVRKLALSSLTVIMANIKTRTFAQGVPYSLIIRKATNPLKKNVTLPENVSNDFAWEYLKSSVAEINYDQPELSMLDDSISTGWLAWPKTFKAYLPRTESFVMPDIDAESRPAYDYLEQFFSQPSFWEKLIEFMAQEPIHGERHDSFSTEHARFFKSIFGLWEDKFLDIVEPVIIKLASTVDDKNSQRSASELIGGLVRGSKHWKKSGLDRLWSWLTPTLKKTFQLCTPDSLVYWERFVKYCCAYRDPRRVLPLITLIFNTPLDKDSAAAFSESKNLFFTRAVLVSLSWRVSLLTSSLREDCLSHITHPYKQVREILGHVINEYFQLTPHPSYKSVSEFLRQQKHEGDAPSAMVESLDEKSSHQIATLVQNLKKWRIERPPAIQGASDYTNASKTVLAWLYQALSGFRVQATYGVVLPLIPELFQMQDISDDQDLQQLATLTLLQLGRFVFPAKMVAEVVDIFCKVLRESTSWHIRNNVLPVLQIFFYTNLFSMNVDMVVKVMDSVSSMLLDPQIEVRQLAASTLSGIVQCSQRDATKKLISDFKHILETTPLPVRNKRDRSAPKDTSQLEGYSEALVKRHGGVLGLSSLLGAFPYDVPKWMPEVMVLLAKYFSDPPPVSTTVKKVFGDFKRTHQDTWHEDQKQFSLEELEVLSDMLISPSYYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUR2</accession>
    <name>A0A9P6MUR2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_011262</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000886">
        <property type="protein sequence ID" value="KAG0013147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUR2"/>
    <dbReference type="OrthoDB" id="4748970at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="1">
        <location>
            <begin position="82"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="1">
        <location>
            <begin position="113"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0013147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="171" mass="19882" checksum="9987253F83B5AB8F" modified="2023-09-13" version="1">MTYLAPAYILVVMDSTCAPSEILAFNGVHLHNPHDSHNGFYEDSDSESNYSGQDLNMAMQLQQQQQQQQQQTINGQPITFHYFCNFPTCDYHSARSDPVKRHRDTHYPDYKPYICNYCQSSSARRDSTREHCLKQHKDDSENAFRHDATIPKPEGWIAYEPKRAPWPPIMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVH8</accession>
    <name>A0A9P6MVH8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent)</fullName>
            <ecNumber evidence="5">5.4.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">PGM2</name>
        <name evidence="16" type="ORF">BGZ80_010342</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:23536"/>
            <dbReference type="ChEBI" id="CHEBI:58225"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="EC" id="5.4.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.2" evidence="5"/>
    <dbReference type="EMBL" id="JAAAID010000709">
        <property type="protein sequence ID" value="KAG0014615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVH8"/>
    <dbReference type="OrthoDB" id="2291at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004614">
        <property type="term" value="F:phosphoglucomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03085">
        <property type="entry name" value="PGM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.310.50:FF:000002">
        <property type="entry name" value="Phosphoglucomutase 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.120.10:FF:000004">
        <property type="entry name" value="Phosphoglucomutase 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.120.10:FF:000005">
        <property type="entry name" value="Phosphoglucomutase 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.120.10:FF:000007">
        <property type="entry name" value="Phosphoglucomutase 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.120.10">
        <property type="entry name" value="Alpha-D-Glucose-1,6-Bisphosphate, subunit A, domain 3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.50">
        <property type="entry name" value="Alpha-D-phosphohexomutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005845">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005846">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016066">
        <property type="entry name" value="A-D-PHexomutase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005841">
        <property type="entry name" value="Alpha-D-phosphohexomutase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045244">
        <property type="entry name" value="PGM"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005737">
        <property type="entry name" value="PRK07564.1-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22573:SF2">
        <property type="entry name" value="PHOSPHOGLUCOMUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22573">
        <property type="entry name" value="PHOSPHOHEXOMUTASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24947">
        <property type="entry name" value="PGM1_C_vert_fung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02879">
        <property type="entry name" value="PGM_PMM_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02880">
        <property type="entry name" value="PGM_PMM_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00509">
        <property type="entry name" value="PGMPMM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="Phosphoglucomutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="Phosphoglucomutase, first 3 domains"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00710">
        <property type="entry name" value="PGM_PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha-D-phosphohexomutase alpha/beta/alpha" evidence="13">
        <location>
            <begin position="15"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-D-phosphohexomutase alpha/beta/alpha" evidence="14">
        <location>
            <begin position="186"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-D-phosphohexomutase alpha/beta/alpha" evidence="15">
        <location>
            <begin position="299"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0014615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="556" mass="60604" checksum="914C10422A141ED1" modified="2023-09-13" version="1">MASIQSIPTKPFEGQRPGTSGLRKRVKIFQQEHYTQNFIQATLDAIPTGAKGATLVIGGDGRYFSENAVQMIIRIAAGNEVSKLIIGQNTILSTPAASNLIRIRKATGGILLTASHNPGGPDNDFGIKYNMSNGGPAPESVTEKIYEITQKLTSYKEIALPPVDLSTVGTQHVGNLEVEIVDSVADYLALLKNIFDFDLIKSFLHNNPDFTVLFDGMHGVTGPYGQQIFVNELGLPQKSVMNCAPKPDFGGGHPDPNLTYAHELVERVEKESISFGAASDGDGDRNMIIGKGAFVTPSDSVAIIAAQADSIPYFKRTGVKGLARSMPTSTALDLVAKKKGYEHFEVPTGWKFFGNLMDAGRLSICGEESFGTGSDHIREKDGVWAVVAWLNIIAAANQSKRAGINDILLAHYNEYGRNFFSRYDYEEVDSEGANKMVDRLRALVSTNRSELIGKDLGHGFVVKDGDDFEYTDPIDGSVSKKQGIRIIFEDGSRVIIRLSGTGSHGATVRLYVEKYESNPSKYQDKTQDALRPLIEVALKLSQLTEFTGRKEPTVIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVR4</accession>
    <name>A0A9P6MVR4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_010646</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000763">
        <property type="protein sequence ID" value="KAG0014108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVR4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050629">
        <property type="entry name" value="STE20/SPS1-PAK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48012:SF10">
        <property type="entry name" value="FI20177P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48012">
        <property type="entry name" value="STERILE20-LIKE KINASE, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="7"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="243"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="248"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="276"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0014108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="588" mass="63980" checksum="7E8C7DF1D6B9B100" modified="2023-09-13" version="1" fragment="single">MECYGKYMDPTLSGSSVFKALDKADNLKPLAIKKIPLSSLSDGLGGSDLNRQVDVDYFISCIADHSGRWRQHIGNYNINENYEETQRESTPKSTVGLDKIVQCLGVHQTDTELWLMNCINAVSPTSVIVLTPSTSHGKHKMGVERLSLEYCGGGSVEDLIRLSDGPLAESEIGWIMSQVLLGVTFLHSKDHIHGDIKASNILLTTDGKIKLGGSGSIMDHKKGAGERKRRRRSLAMIKFPTSWLAPESNPSSSKSPTAASGAEGMDGTMNDDKPQNDASSTKRGQWMPNASATADVWALGIACIELSQGRAPGPDMPILAFFGEKQIVDSQSTVLGRRSDGSLIVNMGWGNIQQTGTFGAARMGMSEEMWSFIARCLTREPESRPSVQELLEDPFIKRYSEPSTEFLERIQRMMEFVDQCASISSDALCDMSSSSLLPSSSSSTLSSSMSSLTLSPSKSSYMVDMKLEEANIAPWVIPMVRPRVDSVYDASSFFDDAGMPTSPPEPGASSNVSGWKHQRVSHPVVKQALLREQAGYMIFRHSRSPSLATIIESQLEEDKEIGLGQVDDHMIGYGGFCGSSLGNTQSCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVW2</accession>
    <name>A0A9P6MVW2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">COP9 signalosome complex subunit 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_010550</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the peptidase M67A family. CSN6 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000745">
        <property type="protein sequence ID" value="KAG0014263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVW2"/>
    <dbReference type="OrthoDB" id="1378at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008180">
        <property type="term" value="C:COP9 signalosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000338">
        <property type="term" value="P:protein deneddylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08063">
        <property type="entry name" value="MPN_CSN6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024969">
        <property type="entry name" value="EIF3F/CSN6-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033859">
        <property type="entry name" value="MPN_CSN6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10540:SF8">
        <property type="entry name" value="COP9 SIGNALOSOME COMPLEX SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10540">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13012">
        <property type="entry name" value="MitMem_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0736">Signalosome</keyword>
    <feature type="domain" description="MPN" evidence="3">
        <location>
            <begin position="23"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU367006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0014263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="315" mass="35264" checksum="64D164FCC68A5902" modified="2023-09-13" version="1">MAAVNQDTTSVVLNQPNNSGLHIAIHPLTLLNISDHYTRTAIQSGHGPVHAIGALLGIQSGREVEIFNSYELQFTLQDGSVRIQDEYFVTKQEQFRQVFPAYDFLGWYSIGHRPTTVDIDVLQQLTVYNESPLFLQLDPNEIPTPARSLPITVYESIVDIVDNQPQPMFIKAAYKVETGEAERIAVDHVAHAATHQEGESSLIAHLSGQRNAIKMLDTRIKLLHEYLQDSVQGRVPKDHDLERQISSLCNRLPTISGQAFEEEFMTEYNDVLLTSYLATVTKGTHVMSEMIDKFNVVASASSHQSHGRPRRGMMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVZ5</accession>
    <name>A0A9P6MVZ5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ca(2+)-dependent cysteine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">MCA1_4</name>
        <name evidence="4" type="ORF">BGZ80_010373</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C14B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000714">
        <property type="protein sequence ID" value="KAG0014562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVZ5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004197">
        <property type="term" value="F:cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12660">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050452">
        <property type="entry name" value="Metacaspase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011600">
        <property type="entry name" value="Pept_C14_caspase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48104:SF30">
        <property type="entry name" value="METACASPASE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48104">
        <property type="entry name" value="METACASPASE-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00656">
        <property type="entry name" value="Peptidase_C14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase C14 caspase" evidence="3">
        <location>
            <begin position="262"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="104"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="111"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="136"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="159"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="218"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0014562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="521" mass="57306" checksum="EBE3221A25965AC4" modified="2023-09-13" version="1">MSQQEVGEPIVNVEKVVTVLPDGRKVIKTIKKITHSYQVQVPAGTPVPEGAHLVSTVPAEVSLPTKTVTYQESSTPAGYSSQSYQQYSTGNAVPTVVVESSVDADGRKVTKTTTTASSSSSGPLLNNAGLFPQGESLANSTPTVVVQSTVDENGRKVTKTTTTTSSTSQGPLSKLFKRFSQRNSKDSKGSSNEQPKPKPSPTIPVAPLAVPQTKVNRTKTEPPRAKPVEEQPPTSKTSYVKTFEAKDADGTKFALSDCTGHRRALLIGINYTGLPNALHGCVNDTVVMKTFLLENKFKEENIRVLTDDQVGTQWMPTKANIMRNLEWLIHDAKMNDSYFLHYSGHGGQVADLDGDETDGMDNCIFPLDHAQNGVIIDDELHNMLVKSLPQGVRLTVVFDCCHSGSALDLPYIYASTGYIRGSNALANLGHELVQGNFDAEAVKELQSKWQKLQLEEKEFNRQVNMKAAKADVIMFSGIRENPFQSYQEMLNNIRELLKDKYRQRPQLSSSRPMNMQELFHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MW08</accession>
    <name>A0A9P6MW08_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Very-long-chain 3-oxoacyl-CoA reductase</fullName>
            <ecNumber evidence="12">1.1.1.330</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">3-ketoacyl-CoA reductase</fullName>
            <shortName evidence="12">3-ketoreductase</shortName>
            <shortName evidence="12">KAR</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Microsomal beta-keto-reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BGZ80_009690</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3-ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a very-long-chain (3R)-3-hydroxyacyl-CoA + NADP(+) = a very-long-chain 3-oxoacyl-CoA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:48680"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:85440"/>
            <dbReference type="ChEBI" id="CHEBI:90725"/>
            <dbReference type="EC" id="1.1.1.330"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Endoplasmic reticulum membrane</location>
            <topology evidence="12">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12 13">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.330" evidence="12"/>
    <dbReference type="EMBL" id="JAAAID010000602">
        <property type="protein sequence ID" value="KAG0015714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MW08"/>
    <dbReference type="OrthoDB" id="5545019at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045703">
        <property type="term" value="F:ketoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141040">
        <property type="term" value="F:very-long-chain 3-oxoacyl-CoA reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030497">
        <property type="term" value="P:fatty acid elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd05356">
        <property type="entry name" value="17beta-HSD1_like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000137">
        <property type="entry name" value="Hydroxysteroid (17-beta) dehydrogenase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03107">
        <property type="entry name" value="3_ketoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027533">
        <property type="entry name" value="3_ketoreductase_fungal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43086:SF2">
        <property type="entry name" value="HYDROXYSTEROID DEHYDROGENASE-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43086">
        <property type="entry name" value="VERY-LONG-CHAIN 3-OXOOACYL-COA REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000126">
        <property type="entry name" value="11-beta-HSD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 12" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="11 12" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5 12" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 12" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="9 12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10 12 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 12" id="KW-0521">NADP</keyword>
    <keyword evidence="8 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 12 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="12">
        <location>
            <position position="211"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0015714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="335" mass="36619" checksum="E6B4E9A479FB14EE" modified="2023-09-13" version="1">MDKIVQFVQKSEHNATAVAIFGAIGVAVVALKALSFLKVLVDVFLRSGINLKKYGAGRGGWAVITGATDGIGKEFAFQLASKKLNIVLVSRTESKLKAISEELEQKYSIETKYYAMDFAKGADEDYQGLQQLLTPLEVTVLVNNVGTNHDIPTPFEQESDKVLKDIIEININAAMKMTKIVVPQMVSRKNGLIINLGSFAGLVPTPFLSVYSGSKAFLSSWSQAIGAELAPKGVHVQNVNTYFVVSAMSKIRRANLLIPMPKPYVKSVLGQIGIPGGASTPNTSTPFYSHAIANWAIDNIFSRGYWVNHNYNLQVDIRKRALKKREREAAAAKSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MW85</accession>
    <name>A0A9P6MW85_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ribose-phosphate diphosphokinase</fullName>
            <ecNumber evidence="2">2.7.6.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">PRS5</name>
        <name evidence="12" type="ORF">BGZ80_010061</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>D-ribose 5-phosphate + ATP = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15609"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.6.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ribose-phosphate pyrophosphokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.1" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010000661">
        <property type="protein sequence ID" value="KAG0015077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MW85"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002189">
        <property type="term" value="C:ribose phosphate diphosphokinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004749">
        <property type="term" value="F:ribose phosphate diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006015">
        <property type="term" value="P:5-phosphoribose 1-diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006164">
        <property type="term" value="P:purine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009156">
        <property type="term" value="P:ribonucleoside monophosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2020:FF:000063">
        <property type="entry name" value="Phosphoribosylpyrophosphate synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2020:FF:000007">
        <property type="entry name" value="Ribose-phosphate pyrophosphokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2020:FF:000005">
        <property type="entry name" value="Ribose-phosphate pyrophosphokinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000842">
        <property type="entry name" value="PRib_PP_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029099">
        <property type="entry name" value="Pribosyltran_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005946">
        <property type="entry name" value="Rib-P_diPkinase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01251">
        <property type="entry name" value="ribP_PPkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10210">
        <property type="entry name" value="RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10210:SF36">
        <property type="entry name" value="RIBOSE-PHOSPHATE PYROPHOSPHOKINASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14572">
        <property type="entry name" value="Pribosyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13793">
        <property type="entry name" value="Pribosyltran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01400">
        <property type="entry name" value="Pribosyltran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00114">
        <property type="entry name" value="PRPP_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ribose-phosphate pyrophosphokinase N-terminal" evidence="11">
        <location>
            <begin position="4"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF13793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0015077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="478" mass="51557" checksum="8F143F4F752B8453" modified="2023-09-13" version="1">MRNIVVFSGSSHPTLVDQICARLGVSPGQVKLTKFANRETNVEIGDSVRNKDVFIIQSGCGAVNDNLMELLIMLAACKTASAHRITAVIPCFPYARQPDAPYKKNGMPLSRVPRDVFFGYTGSSTPFSLPVTPAVTPLQTPSLDRADRKNPFDKMFDSTNESNSDIESAATSPTLSPAAGIHGNGSGFVPTLSTLRSEGAGNHSDLVKKGLLAPRGIRPQPNPLTAQAGTPAILTNGVAAGGQTCVTSDQVNPQKAGYKHWVARSGTLIANLLVTAGADHIITMDLHDPQFQGFFDIPVDNLYGQPLMVKYIRERIPNWEDAVVVSPDAGGAKRATVIADKLGMEFALIHKERRQVQAPHKPDMMLVGDVTGKTCILVDDIADTSFTITKAAKVLQQNGAKKIYAIITHAIMSGDAINRIQNSCIDQVIVSNSIPQEEHLQNCPKMKVFNVAPIFAEAIRRIHNGESVSMLFEVMDLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWI1</accession>
    <name>A0A9P6MWI1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glutamate-rich WD repeat-containing protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">RRB1</name>
        <name evidence="7" type="ORF">BGZ80_010143</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000676">
        <property type="protein sequence ID" value="KAG0014934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWI1"/>
    <dbReference type="OrthoDB" id="2161379at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051972">
        <property type="entry name" value="Glutamate-rich_WD_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022052">
        <property type="entry name" value="Histone-bd_RBBP4-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45903">
        <property type="entry name" value="GLUTAMATE-RICH WD REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45903:SF1">
        <property type="entry name" value="GLUTAMATE-RICH WD REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12265">
        <property type="entry name" value="CAF1C_H4-bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Histone-binding protein RBBP4-like N-terminal" evidence="6">
        <location>
            <begin position="92"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="298"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="342"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="392"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="162"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="28"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="168"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00040876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0014934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="495" mass="55566" checksum="992D30B8FC9D1203" modified="2023-09-13" version="1">MSKRIQDNDEDMREAKSAFNVGNRTTVEDEGMGEFEDPWEDEVESDQEVIVENDDDDEEGMDLDQANEMDQDKEEDDKEVRVYLPGQALDKDEVLEADQSAYEMLHSMNVKWPCLSFDILWDQLGDERCTFPATAYVVTGTQADVAQNNEVLVMKMSQLAKTKNDDGNLSDDDSDDDDVDEDPILEHRSMKHIGGVNRIRAMPQRDQQIAATWADTGKVHLWDLAPHIRSLDQPGTTIPESAKRPIYTIESHGRYEGFAMDWSETVPGRLLTGDLNGKIYLTTLDCSTGSVTPDRVPFVGHQSSIEDLQWSPSEKGVFASCSADQTVRIWDIRSKKRAGLQVKVHNSDVNVISWNRKLPYMLASGSDEGVFSVWDLRQLSQNAANPTPIATFKWHQAPITSIEWHPTDESVLAVAGADDQITLWDFSVEHDAEETLNGTSQKAIVNEAGIEVPPQLMFVHQGQQDVKELHWHKQIPGCVISTAESGFNIFKTISI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MX16</accession>
    <name>A0A9P6MX16_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_008825</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000492">
        <property type="protein sequence ID" value="KAG0016893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MX16"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="3">
        <location>
            <begin position="6"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="59"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="124"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="64"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="92"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="106"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0016893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="169" mass="19409" checksum="48351CD1F135E42D" modified="2023-09-13" version="1">MIPVIACANCKRSHIKCDSGRPCQNCLKHPSKALTCRDAIPKPRGRPKGGSKAAAEAIFQARLQQQQQQQQQQQQQQLRDQYQGHISRPRMMSQSSCGQSPVSVKSEPKEIDPVGDHDADMLLLLQQKYEAEAELQRIQQLQKELQEQYENQQVLYSLKKQQQQKQHYC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MX46</accession>
    <name>A0A9P6MX46_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">COP9 signalosome complex subunit 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">FUS6</name>
        <name evidence="9" type="ORF">BGZ80_008733</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CSN1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000484">
        <property type="protein sequence ID" value="KAG0016976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MX46"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008180">
        <property type="term" value="C:COP9 signalosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019585">
        <property type="entry name" value="Rpn7/CSN1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045135">
        <property type="entry name" value="Rpn7_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14145">
        <property type="entry name" value="26S PROTESOME SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14145:SF2">
        <property type="entry name" value="COP9 SIGNALOSOME COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10602">
        <property type="entry name" value="RPN7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0736">Signalosome</keyword>
    <feature type="domain" description="PCI" evidence="8">
        <location>
            <begin position="285"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="497"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="37"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="52"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="499"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0016976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="558" mass="61788" checksum="173412A2494E06C1" modified="2023-09-13" version="1">MDPRLSPDRTNLSPNPGMMDTSADNSHNMESEMYSDNIGTPSSLSNVTLTADGGNNSQDNNNSKRKRFVKVVEVDVPNNLDLDAYIANYKGHTKVNRLEFIADRCPSLQVDALKLAITELRNASTLNIPRYANLVKKLNEAVKFGASGSANVSSDLLNVDKAWADSQLQKAKQQTDLLEGELKTYKRNAIKESIRMGNIELGNHYYSCGDLTSAHRSYARTRDYCTTPKHIIELCMNVIKVSIELGNFPHVLTYVVKAESTPEVQQDKDLTKAKLKAASGLANLDLSKYSAAARDFLSIGEELVGHQYGDVISANDIAVYGGLCALASFNRAELKRLVIDNVGFRQYLELEPHIRDLIQGFYNSNYTVCLDIMEKWRNDYLLDLHLHSHIEALYTNIRKKALVQFTSPFLTVNLTKMAKSFSTTVPELEKELVSLIIGGQIEARIDSQQKILWAKQTNKRSAIFERTTAMGQEYEREAKGLVLRMQLINHNLIVKGAGSEKGGPGGGGDVDVAFEHGAHPRGGRTGGVPGGRDIPMFADARAGMSNFLSTFARDRHRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MX99</accession>
    <name>A0A9P6MX99_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ketol-acid reductoisomerase (NADP(+))</fullName>
            <ecNumber evidence="6">1.1.1.86</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Acetohydroxy-acid reductoisomerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15">Alpha-keto-beta-hydroxylacyl reductoisomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="primary">ILV5</name>
        <name evidence="20" type="ORF">BGZ80_009651</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 2/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 2/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 17">Belongs to the ketol-acid reductoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.86" evidence="6"/>
    <dbReference type="EMBL" id="JAAAID010000598">
        <property type="protein sequence ID" value="KAG0015745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MX99"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004455">
        <property type="term" value="F:ketol-acid reductoisomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:L-valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1040.10:FF:000003">
        <property type="entry name" value="Ketol-acid reductoisomerase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1040.10:FF:000005">
        <property type="entry name" value="Ketol-acid reductoisomerase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000167">
        <property type="entry name" value="Ketol-acid reductoisomerase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013023">
        <property type="entry name" value="KARI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000506">
        <property type="entry name" value="KARI_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013116">
        <property type="entry name" value="KARI_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00465">
        <property type="entry name" value="ilvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21371">
        <property type="entry name" value="KETOL-ACID REDUCTOISOMERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21371:SF1">
        <property type="entry name" value="KETOL-ACID REDUCTOISOMERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01450">
        <property type="entry name" value="KARI_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07991">
        <property type="entry name" value="KARI_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51851">
        <property type="entry name" value="KARI_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51850">
        <property type="entry name" value="KARI_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 17" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="14 17" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="9 17" id="KW-0460">Magnesium</keyword>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
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            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
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                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
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        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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        </source>
    </evidence>
    <sequence length="1321" mass="145293" checksum="F5C92DF0021353C5" modified="2023-09-13" version="1">MARDSDYEGSEIQNGGFQDAANRSSRHQDQFYGYNNNNSNNSNNSNNYHRPGSSISPSRNNHNNTNYPQQQWNNNSNNSNNNNLHRNNISHGGRPLDHQRNNHHSQSRNQSYNDSDRSRTKRQMRTFSTDDGGDRNETHRRGSSPHYHHNQQHQQQQRRALPPQDEIIPGLPKKNFHDNRHQQHQNHNYSQNNNNNNNSSNVGNRPRTNSIDQTFNPRRGRSTDDVRSREGSNSFTATDQHGSNNNRYRSNNFQNDYGDRTINRHHSNQSYSGGRGRHHDLSPKRSNSNSSTSPHNQYRSGNFRSPTPDARSPREGSRTPQFSPGRRHSQNYGRRDDRGGDYYHDQDSFENRKRRRSPSPIRSDAQQDSSSKGKYNSYTYPAQETNASEWDKGPLQGSMPREYTEYLSTLPPTLMNPSLIADDQQSDSSSNLPALNSLTSVIPLLMQLHQQQQLSLQQQPQIPLALGSVPPFPFPPIPPPVPPPAFGGIGLMPGTIQPALIPPQQPLANNQYTIASATIPPAAHTAMATVPEKANIDPTMMADRPREDKSSNADKGNTGLAGHLATDTGLVGDSIDRGVNKEARAGEALMDNTKDLDKTQSYDNTVMIRPKEAIVNAVSSMAGSEHTKQGQKRLEQERPSQSSQVTAGPPPPLPNADPLAAILSDPLTAKLLETIQPFLVQRATNPDPVSDVATDTAINPTPSSTLESKQETAHHSTQDTSKGTALGVALDTAPGPHKPESKHPDMGMGAAVGLDNRTSLNDPVDGNMANVVASTAVSEAEAPMRPLDSSLNPGVPQTQVDEVLSKHGDGKISGGQEPGSEVKEDSEGGDKRSSDKVTQALISSDINVSSKNNQEAISQDTMVSDDAASADMSVLEPSENINQSQDPSSTGVRSPSMESDMEISSDEGEVDHVIVTQPESAPIAESTIANANDVAEKKEGSAVSTKPTTDNTPNVETHQAIETVKAPASDSVSNIEKHTSEEETPKAASKILTGYQAESEPIDGPSDMEIDGPQTVPEVRPSFSPKPIVVAGATSSATNGQPERSLSDRVLKQRQRSSSSPSLSSQIRAGTQPGQRSHYQQEHQQKQQSYPSWHFVPGSDIALLSEMAASKADLNRFRRESAWLEERVRRPRRDADSENVLDKALGLTRNVPHPNQEKRARSNSGSGSGSGSGSGSGSGSGSGVADSAVRLSSESRVAFSILKTNLQSDLEEQTRLETDYQTLQRALERMQVKIVEKQKLQKEAEQQIQEVVHRQSELELELQKVREQEEACLRQRELQRKQAEDEIKQLEATLRTLEQQQQQQQQQQQQEHRQEQGLLQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYT9</accession>
    <name>A0A9P6MYT9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_007924</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>(R)-lactate + 2 Fe(III)-[cytochrome c] = 2 Fe(II)-[cytochrome c] + pyruvate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:13521"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16004"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="1.1.2.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FAD-binding oxidoreductase/transferase type 4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000416">
        <property type="protein sequence ID" value="KAG0017777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYT9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004458">
        <property type="term" value="F:D-lactate dehydrogenase (cytochrome) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.2190:FF:000001">
        <property type="entry name" value="D-2-hydroxyglutarate dehydrogenase mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.2740:FF:000002">
        <property type="entry name" value="D-2-hydroxyglutarate dehydrogenase mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.43.10:FF:000002">
        <property type="entry name" value="D-2-hydroxyglutarate dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.45.10:FF:000001">
        <property type="entry name" value="D-lactate dehydrogenase mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.45.10">
        <property type="entry name" value="Vanillyl-alcohol Oxidase, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004113">
        <property type="entry name" value="FAD-bd_oxidored_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051264">
        <property type="entry name" value="FAD-oxidored/transferase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016171">
        <property type="entry name" value="Vanillyl_alc_oxidase_C-sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43716">
        <property type="entry name" value="D-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43716:SF1">
        <property type="entry name" value="D-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02913">
        <property type="entry name" value="FAD-oxidase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="FAD-linked oxidases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="7">
        <location>
            <begin position="45"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00051436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0017777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="418" mass="46397" checksum="359944F8896A2A85" modified="2023-09-13" version="1">MKRNESFKKLSEDDLSYFKSVLAPHSITQDEEDLEAFNTDWLRKYKGQSKLVLKPSSTEQVSKILKYCNDNKLAVVPQGGNTGLVGGSVPVFDEIIISMSNMSSIRKFDNVSGALVLPDGTILDNLSTLRKDNTGYDLKQIFVGSEGTLGIVTGVSFLAPKKSKAVNVALLGLNSYDHVQAAFKRSKEELSEVLSAFEFWDQDALKLVKDHLAAGANDPLQSTYPFYVLIETSGSNKDHDDEKLNNFLERLLTDNITQDGVVAQDTTQLRNLWAIREGIPVACLHDGAVYKYDISIPVPVIYQAVEELRKRLLDRGVLGEGKLFTSVIGYGHIGDGNLHLTLAAKEFCEEATDLIEPYIFEWTAKHAGSISAEHGLGICKNNFLSYSKSSSMIQLMKRFKQLLDPNGIMNPYKFLPDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYV8</accession>
    <name>A0A9P6MYV8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008239</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000440">
        <property type="protein sequence ID" value="KAG0017491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYV8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0017491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="854" mass="95846" checksum="319A0A0E3BF2E93C" modified="2023-09-13" version="1" fragment="single">AQLPGPEYKSEIDPRGPKTWSHNVIKTMAVDLVQGRIRHPMVIDDPDDDSKGKKKPRFGRADRFAERYQTEHKAGSSLRLDSLGVPVRGPHQGFGESRYLCPDKSKFGNPSGHSLAPSTPRPGGIEIMALEWTSNMPRCSDINLEKNGKMLSIVFGRVKYYLPIDNITPAELQCLLGSTFKSRAQRLCVDIVAAGEYYNISFDGGIHACSSLSEAMEKADILLGAFAFGRDPFTGTLFKPNPGQLEGYKNPILETVRLLNTDKEYAEARCRYRDVFLHPTLVCNGSFAIPATSVLDWWPELDFPKTVFKLVCRIVLIDLNDNPHYYDIPESSAIDPEAEILLRPYKPLIETFKKHGAEWIASEPVLRKVETAAKVFQVLSMVRSSRTGANPLPSLPTTTLTDHKRVDKRTDFRDPAPNSGEPNLVCQAFRSALLSAIPLTKDTLDRASQYLSLGLMCFKLTSFDEATEYLLKAAEHYNSQTTAGYMATKGLRNCFVYILHSLIATLGRGDDYSWILDKKEDCPVWWISLHSVFGPVLDEFDSVVRELRSDKVDSEMAKAAVPLCVEMLIIHLSYAMLTWFEQQQDLEGILPVYEVLAFLYSRGAIKKDIQTERWPSIEKASTALGEQMYAWANKDIITVQEGLTSEDSPVREDDLLDLQEKLMDLYVVKGEINKAMVCALVSVRMQEELNSSIDDRARVLEKAAMIARTARAKKDVDAAKAIIERAENLLQNRDRLHWRKSEIGIKRALLTSLNNASMLLYSHDQELEKTAMLLMRRARVVIAEVNIEDPAIAAKWVIAAQINQEAAKSMKDDVGLNRYANKWLLDNSKIAAANLIGNVLDGMLLLLLREIINS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZ19</accession>
    <name>A0A9P6MZ19_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_008001</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000421">
        <property type="protein sequence ID" value="KAG0017708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZ19"/>
    <dbReference type="OrthoDB" id="206201at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04077">
        <property type="entry name" value="Peptidases_S8_PCSK9_ProteinaseK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.200:FF:000014">
        <property type="entry name" value="Proteinase K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.80">
        <property type="entry name" value="Peptidase S8 propeptide/proteinase inhibitor I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034193">
        <property type="entry name" value="PCSK9_ProteinaseK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010259">
        <property type="entry name" value="S8pro/Inhibitor_I9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037045">
        <property type="entry name" value="S8pro/Inhibitor_I9_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF11">
        <property type="entry name" value="CEREVISIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05922">
        <property type="entry name" value="Inhibitor_I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54897">
        <property type="entry name" value="Protease propeptides/inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5 6" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0720">Serine protease</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040473695" evidence="7">
        <location>
            <begin position="17"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="Inhibitor I9" evidence="9">
        <location>
            <begin position="30"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="8">
        <location>
            <begin position="136"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="145"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF05922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0017708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="386" mass="39655" checksum="990D5F2EC2B1E593" modified="2023-09-13" version="1">MKYTFILAAVIAIAQAAPLISNGGKPISDSYIVVLKNGHTADSFQPKFDDIARRQNGRGRKPTIHRKFNRFSGFSATVNQAALKELLASPEIDYVEQDAIITLTGSQSSPPSWGLPRVSQHNKDLTQAYLYNDAAGEGVTAYVIDTGVYVDHDEFEGRATFGANFIDGSADTDENGHGTHVSGTIGGATYGVAKKVNIVGVKVLDASGSGSTSGVVAGMDWVASKATPGSSVINMSLGGGKSKAIDDAAGRLFAADIPLIVAAGNSATTNACNGSPSGAANTFTVAASDRNDRVASFTSYGSCVEIFGPGVGITSSWIGSPDASNTISGTSMATPHVVGVAALYLSFNSLPTAQSVFDKLISTATTGKITGSLKGSPNRLVFNGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZA9</accession>
    <name>A0A9P6MZA9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007377</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000376">
        <property type="protein sequence ID" value="KAG0018278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZA9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040247283" evidence="1">
        <location>
            <begin position="24"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0018278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="55" mass="5861" checksum="A12EA20707B57548" modified="2023-09-13" version="1">MRVHTYIACIAAAALALVSMTSAAPAIPEFLPVPKEDFPMCCLHNVAACCLLEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZH7</accession>
    <name>A0A9P6MZH7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007115</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000359">
        <property type="protein sequence ID" value="KAG0018481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZH7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="213"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="104"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="317"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0018481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="351" mass="37286" checksum="36C4CD6A0E9CBD52" modified="2023-09-13" version="1">MYIPLMHAILEQHQFLPDTIVLVGDSVSTARRSSDGLKPRELICTLYSTDRLQYLHLHHCHGKPLPPVSSSLLPSIHDRPLADSSTSPQSSRASHSYIQQQPVVATQQPVSQPQPPVSGSSSRLLTGISPAPTAMGRGQPNMPGFGNVSPVEPIYVGSNRNSHYGSPLLVTNVPLPPGAHNPLVHLPVVNSPVVMTAYQPQTQYYPGNYHPASSGPMAATSSVGPSQAGTMAPVTSTPAAASLSRPVSQQGFVSTNSSHNGGNINGPGTANSGASQNLLNEMAMYSGDRSRSHLRQSQPPKPTHPRQIQSQEARSLSSEELKLDSKTGGHVKAIMKGVNAKWSEIRKAGIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZY2</accession>
    <name>A0A9P6MZY2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006347</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000313">
        <property type="protein sequence ID" value="KAG0019064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZY2"/>
    <dbReference type="OrthoDB" id="5279943at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="24"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="263"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="282"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0019064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="537" mass="60711" checksum="C6FF7DF5FD022C35" modified="2023-09-13" version="1">MSLLQSSKISFVELSKRDSPLGGRRPTTITTTTKTTRRDPTEDDDSDHLEDMMTDSAIAGTPPFDLEFDSGDDYDDDDGNSDLPSMRSLVSPPSFQSVPILDRKRKDSQGHVSPVHLLDCNVTSQQEEFGYGHLPAPALDNSFNSKGGSAKGRRPTVTFCLDEPATSPPSSSPPAKLNMIQRPNFNCVRFRHDDDDDVVAVTVATTADAVANDSNGQDMTPTKESRQNDSAVHNVERALRRVSISLAEDEDEDEDEDEDDDKDNGRDQDKVDNQDTDHNTVAQSTSQNASPNSNPNKSTTTNTDINPPQEIILNHIQSETAPQDMLVALFDRPSELEALAARHSEFFNVMYSSLLFNANCNEFKKMLFQPREVLSDRDWMKAISERLESLPYILEKFKSIVGWIGPDSLNDSDDSDSYYGDDTFWGEDEYGCRDSSFENVQIKWFRDIQEEFPLETFQECYPQFFINARECLEGKRMSYGGDQRDQYVIFCETLDLTREDLQCDSAWVRRMNGCLEKHPELMLQLKEIIAYEVDYDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N040</accession>
    <name>A0A9P6N040_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Translocon subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">SEC61_1</name>
        <name evidence="14" type="ORF">BGZ80_006818</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the SecY/SEC61-alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000339">
        <property type="protein sequence ID" value="KAG0018732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N040"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3370.10:FF:000002">
        <property type="entry name" value="Transport Sec61 subunit alpha isoform 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3370.10">
        <property type="entry name" value="SecY subunit domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002208">
        <property type="entry name" value="SecY/SEC61-alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030659">
        <property type="entry name" value="SecY_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023201">
        <property type="entry name" value="SecY_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019561">
        <property type="entry name" value="Translocon_Sec61/SecY_plug_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00967">
        <property type="entry name" value="3a0501s007"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006341">
        <property type="entry name" value="PRK08568.1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10906">
        <property type="entry name" value="SECY/SEC61-ALPHA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10559">
        <property type="entry name" value="Plug_translocon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00344">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004557">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103491">
        <property type="entry name" value="Preprotein translocase SecY subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00755">
        <property type="entry name" value="SECY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00756">
        <property type="entry name" value="SECY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 10 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="33"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="75"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="145"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="244"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="416"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="440"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="domain" description="Translocon Sec61/SecY plug" evidence="13">
        <location>
            <begin position="41"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF10559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0018732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="475" mass="52177" checksum="C0D4E57F7AF9151B" modified="2023-09-13" version="1">MAGFRFLHLIRPFMAVLPEIAAPERKVPFRQRVLWTAVTLFIFLICSQVPLYGIMSSDSSDPLYWMRAILASNRGTLMELGITPVVTSGMFMQLLAGANLIEVDYSLKEDRSLFNGAQKLFAVLIAVGQATVSVMNGLYGPPSELGAGICLLLILQLVVAGVIVVLLDELLQKGYGLGSGISLFIATNVCETILWKALSPTTYNFGNGPEFEGALIALFHLLFTRSNKSRALKEAFYRDNLPNVMNLLATILIFGIVIYLQGFRVELPVKSSRFRGQRGTYPIKLFYTSNMPIMLQSALTSQVFMISQMVFNRFPENILVRIFGTWSPYQGTNQMIASGGLAYYISPPHSISEAVLDPIHTVVYVTFMLTACALLSKTWIEVSGSSPRDVAKQLKDQNMVMAGHRDASMYKELKRVIPTAAAFGGAVLGAVSVFADLIGAIGSGTGILLCTTIIYQYWEMFVKESIENSGDALAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0B8</accession>
    <name>A0A9P6N0B8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Ferrochelatase</fullName>
            <ecNumber evidence="12">4.98.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">HEM15</name>
        <name evidence="14" type="ORF">BGZ80_004027</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the ferrous insertion into protoporphyrin IX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>heme b + 2 H(+) = protoporphyrin IX + Fe(2+)</text>
            <dbReference type="Rhea" id="RHEA:22584"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:57306"/>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <dbReference type="EC" id="4.98.1.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Porphyrin-containing compound metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the ferrochelatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.98.1.1" evidence="12"/>
    <dbReference type="EMBL" id="JAAAID010000210">
        <property type="protein sequence ID" value="KAG0020540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0B8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004325">
        <property type="term" value="F:ferrochelatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006783">
        <property type="term" value="P:heme biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00419">
        <property type="entry name" value="Ferrochelatase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03411">
        <property type="entry name" value="Ferrochelatase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1400:FF:000003">
        <property type="entry name" value="Ferrochelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1400">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00323">
        <property type="entry name" value="Ferrochelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001015">
        <property type="entry name" value="Ferrochelatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019772">
        <property type="entry name" value="Ferrochelatase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033644">
        <property type="entry name" value="Ferrochelatase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033659">
        <property type="entry name" value="Ferrochelatase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00109">
        <property type="entry name" value="hemH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11108">
        <property type="entry name" value="FERROCHELATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11108:SF1">
        <property type="entry name" value="FERROCHELATASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00762">
        <property type="entry name" value="Ferrochelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53800">
        <property type="entry name" value="Chelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00534">
        <property type="entry name" value="FERROCHELATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="6 12" id="KW-0408">Iron</keyword>
    <keyword evidence="10 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 12" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11 12" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040445238" description="Ferrochelatase" evidence="13">
        <location>
            <begin position="22"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0020540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="392" mass="44103" checksum="E73FA85330B88655" modified="2023-09-13" version="1">MIFTSSLNLTRLFFFVYVVSALRSFATVSSDSKDAQKPKPKTGILLMNLGGPGTEDEVHDFLLRLFSDGDLIPLPFQKYAAHFIAKRRTPKIKEQYNKIGGGSPIRKWTTEQGTAMEKLLDKISPETAPHKHYIAFRYADPLTPEALEAMKTDGIERAIAFTQYPQYSCTTTGSSMNELYRHLQRFDPERKIKWSVIDRWHTHPGLIQAFANHIEAGLEKYPAETRDKVIIMFSAHSLPMDAVNKGDSYPPEVATTVNAVMDKLKFKNPHKLVWQSQVGPKPWLGPQTIKAILGLGEQGHKDQLLVPIAFTSDHIETLFELDLEYGEEAHEAGVTGLKRAESLNADPVFIEAMADIVKNHLKDGSLSSKQFAIRCSSCTNETCANMREYFKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0M2</accession>
    <name>A0A9P6N0M2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_005758</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000283">
        <property type="protein sequence ID" value="KAG0019489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0M2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RRM" evidence="2">
        <location>
            <begin position="83"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0019489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="193" mass="20855" checksum="539FDEA667D3C1BE" modified="2023-09-13" version="1">MNNLQAGGLIDIGNSDINFESNCGSRSELPSIPSLDPASSAESRHFSPELMDLDNGPVFFRRAALLTPGITIKGEGGPVTIEIENLHPSTTAEDVMVACSRYGEIQTCMCSSGYAQVTYFKKIAGLAAISMLDGKYSDNGKAHGMIAYENTVTFEWRLLNFTTSKTPRSNIASDHEGNSRNPLPASKRCKLNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0T8</accession>
    <name>A0A9P6N0T8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Kelch repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005336</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000264">
        <property type="protein sequence ID" value="KAG0019722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0T8"/>
    <dbReference type="OrthoDB" id="2430752at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="307"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0019722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="333" mass="35873" checksum="712F47A348E3AF43" modified="2023-09-13" version="1">MDSTQNYSVFASTPISELSGTTANWTKLPDPPQWKSMTSYYPSSQFDCAATSDGKVFLFGNDVGFAQYDIQSAKWDDTPPKFTSTGVSMKNLLNQQGLRATVDIDRTSIVIVSSSPPTFMRLNPQTKEISGTSIYTITSGLRGFCLGIIQKNPEKVILCGGSYYHQESSCYELVTQSTSVYTNSFNSLPSSQEGCSIVSHDAGYFVNQGLMSSNANAPSWTDNNSGSSSSVFYSVQNGLWTEYHNSLSNSYPLRGYSAATYIPNMKMAVIYGGVLPGQNTSSEIYTLNLTDTISSYKGDSGSSSSSGFSLIGLLAKIFGSLFGIGVVLGILKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N197</accession>
    <name>A0A9P6N197_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein cbp3, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">CBP3</name>
        <name evidence="4" type="ORF">BGZ80_004629</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CBP3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000234">
        <property type="protein sequence ID" value="KAG0020191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N197"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034551">
        <property type="term" value="P:mitochondrial respiratory chain complex III assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021150">
        <property type="entry name" value="Ubiq_cyt_c_chap"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007129">
        <property type="entry name" value="Ubiqinol_cyt_c_chaperone_CPB3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12184">
        <property type="entry name" value="UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX ASSEMBLY FACTOR 1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12184:SF1">
        <property type="entry name" value="UBIQUINOL-CYTOCHROME-C REDUCTASE COMPLEX ASSEMBLY FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03981">
        <property type="entry name" value="Ubiq_cyt_C_chap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquinol-cytochrome c chaperone" evidence="3">
        <location>
            <begin position="117"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="11"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="32"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0020191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="268" mass="29725" checksum="FCFE9CB8F842CFD6" modified="2023-09-13" version="1">MAPSSIIARTGLQTARTFATSQSHSKQSAPDSTSVSSSVPPASSSSSSPSSSPTSSSSRPATTTRSEATGLYGGFLRSLAMVTGHYTVSQTAMRSTHNFYEICALQLQEKKSFWIDTCGLPDNFQTWFSVTHLHVWLLMVRIRAEKHGKVFQQQLVNHFFHDIEDRMRYNHKISSGRIISTYMHDFLAQFHGGVLAYDEGMCKDDPIMAAALWRNLFTSSGTPQQIAILVDYVRKELQILDNINSDDFLESRVLFGTHAPALRGVPGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1Q2</accession>
    <name>A0A9P6N1Q2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_002076</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000150">
        <property type="protein sequence ID" value="KAG0021609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1Q2"/>
    <dbReference type="OrthoDB" id="2143914at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019185">
        <property type="term" value="C:snRNA-activating protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001006">
        <property type="term" value="F:RNA polymerase III type 3 promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042795">
        <property type="term" value="P:snRNA transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042796">
        <property type="term" value="P:snRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051575">
        <property type="entry name" value="Myb-like_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46621">
        <property type="entry name" value="SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46621:SF1">
        <property type="entry name" value="SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13921">
        <property type="entry name" value="Myb_DNA-bind_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Myb-like" evidence="7">
        <location>
            <begin position="11"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="9">
        <location>
            <begin position="19"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="9">
        <location>
            <begin position="65"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="7">
        <location>
            <begin position="65"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="7">
        <location>
            <begin position="116"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="9">
        <location>
            <begin position="121"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="662"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="798"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="174"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="315"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="728"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="189"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="317"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="730"/>
            <end position="744"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0021609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="833" mass="91491" checksum="7B5698828991AE83" modified="2023-09-13" version="1">MAEDQTAPRKRIRGERIVWTPEEDEFLRKAVQKYGDKTEKWAKIAACVPGRTNKNCRKRWFHSLDPSLKKGGWTEEEDHLLRTGVEMFRGQWSKIAERIQGRTDDQCAKRWRESLDPDIDRAAWTPEDDNLLLQKFEEYGTQWQKIAALSFPGRPGLHCRNRWRKIQRSLNHMQRANKRRRNQFDIKDGTSSWTQSSDIHMEQDDGSGNQSGGGQKLSSEDALLQESYLDDDCGLLEDSVDNGDGKNDSNSDEERPYGCAIPDCSFESSSPSLLFYHFKASHHGTTVLKPFRCTMPGCEDRKRYKNINGLQYHVNHAKNTPGHSGHGSSNQELEQNAKASSATPVEENAPSPGSDALSPFLATVANPVSTPRSSIPTPAEIQSLILPAIPQSIVTHQAFNIPHTPESLEEPVMSSPVSRDTALSQARSTTLQCPELGCGQIFHALGSLTSHMANNHGHQSMTMESNDATYGRDSIAIPENNFNNVGTDMDMDMAYLASEHPSPMVENGNNMLLMDDAELQAHFDRLTRNQEAMSLDSNTISGIPTTADQELDILAMNKLLFANHISYMLNTAINSNSFSNRIHFGTHINVSADDPFTLPSTPVTSANVSPRMSAAAINIPADARTDSEPIPFRNRELAATPFAAGATFANTGTAVPTVTKKFPCLANECPKSYGSSSAMWTHMKNEHPGTYVKPARGKSASANAGYNANINNGSGLFMADESRALANFGTSSSPSSATMPTPESLVSPGSPESATSTISWMHAMNGNNANEELQTDRGHGAIKQQRQSRKFDDQEKPFKCLVPGCGKGYRNINGLKNHLLQAHGSTPKKNGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1U4</accession>
    <name>A0A9P6N1U4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Mini-chromosome maintenance complex-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_001771</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000141">
        <property type="protein sequence ID" value="KAG0021756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1U4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019140">
        <property type="entry name" value="MCM_complex-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13489">
        <property type="entry name" value="MINI-CHROMOSOME MAINTENANCE COMPLEX-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13489:SF0">
        <property type="entry name" value="MINI-CHROMOSOME MAINTENANCE COMPLEX-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09739">
        <property type="entry name" value="MCM_bind"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0021756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="547" mass="61444" checksum="F6469CE0AE5CF289" modified="2023-09-13" version="1">MNVIDQPLKIVQELFEKNWKKEQPTERTEFGVTEHFQELFSTREELLKIPELNSQSIKTLPLNSLVRFRCMIQDTELSQEVALFTSNTITKPDGEEKLICHRYSDGPQEGHTLETDNSQTLMDLRNSYYCISVPGETQWVKDYERSEHNSLNASLQEDESPSQVIPERYPFPGVDHFSAIMKTHSSDASIGVTDMVEVIGVLGARDKLMTGDSFDFHDESANSPLIPTVHAILIRKIDDHGHPELSLSGRPDESDIMFYSEESQAIRKDLIQYIASALQGDQLAAELVLLHFLARVHSRVNGVVLGKFSLNIRDSSPNSPVFHNLSLVMKSILPKVHTIPLSLKCLNDNFFFPRGDEHLSSGILQVTRGTAMLLDETVMEEGTLTDKGVKNLKAVSDVSQYQTLNYVFPYSNLEFQTDISLLILSNGNSLIPVDCAITLKPEPSTTEALIEPTLEQLKSYRKYLSVLRLAECRFPEEMAKEIENEFMEQRKAATAAGTSLITPNDLAFNISLARLVASSRGEQSMTKQSWDHAVTLSKHIKARGGKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-10-08" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1Y6</accession>
    <name>A0A9P6N1Y6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">WD40 repeat-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_000773</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000117">
        <property type="protein sequence ID" value="KAG0022202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990234">
        <property type="term" value="C:transferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.80">
        <property type="entry name" value="E3 ubiquitin-protein ligase SopA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056251">
        <property type="entry name" value="Arm_rpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847:SF637">
        <property type="entry name" value="WD REPEAT DOMAIN 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23948">
        <property type="entry name" value="ARM_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25173">
        <property type="entry name" value="Beta-prop_WDR3_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05729">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141571">
        <property type="entry name" value="Pentapeptide repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Arm-like repeat" evidence="6">
        <location>
            <begin position="298"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="domain" description="NACHT" evidence="5">
        <location>
            <begin position="766"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1308"/>
            <end position="1349"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1350"/>
            <end position="1391"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1392"/>
            <end position="1433"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1434"/>
            <end position="1475"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1476"/>
            <end position="1517"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1518"/>
            <end position="1552"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1560"/>
            <end position="1601"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1602"/>
            <end position="1643"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1644"/>
            <end position="1685"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1686"/>
            <end position="1727"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1728"/>
            <end position="1769"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1770"/>
            <end position="1810"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1811"/>
            <end position="1844"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1102"/>
            <end position="1138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1910"/>
            <end position="1935"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1116"/>
            <end position="1137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1910"/>
            <end position="1927"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF23948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0022202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1935" mass="217164" checksum="DFCB0B36145BA76D" modified="2023-09-13" version="1">MRHSAPTHDKQGAHSKAHHGHPAKTEHPAVMLATGSEQNIEHELHKFAREPTQEANHKISTMPRNPFASHKNGLSVDDALELASHALENARKAKNKPAMALQLCNDAKSKIKDAENIFGTKKDRNPTLGNSIAIAYHEHGKLLNELGYHDKALRSHNKAEKWGYVHAVSQCTDSPQPTSIQLPTPAAAVSASSSNAATVHQDLSETRHFDYQDVSQDVALTEVNKGLSAPKKDVEQVPRNYFEQDVILPVVKYDLPDPGGRITSTPQLAYCLTLISPSLISEESLDENERDWLQGEFNDPDTQERLREMATDLIREFVRDELKKHEVVTEVVSLAAVLEQEDFERLLQVLVGGINKSLLLEDHLVDGLAQLIRNAPQRFIDADDLVKILELLHARLKDIHKQSVQRTYQLTRAISQVLDSMVDSQVDGLSRESLHEPLSNCLKELKELPKDSDPYLTYQAAYAYQALLYVPDDESILQSMMRRTGKVVQGISGVVAAVKALDVVGFVEGLQGIQEGLAGTGKAIELVNNAYEDIKALTESGQGLLESLKEGFSFERKSSWYPALRGLDSLLQGGRFKEFEKLIRESPCRRNPAFQWGVCQRLGEIASNPIWGIKIRKCAVSFLLELYNDDSGWACQTFIKQWILCLLDLSTQSLQGITVDDTQKLLQEVRAVGSTDRLTLRRDTEKYGTTSYPMMFTPPSQESPLLNRVQNKPDVETPLSQLKRERLQGRGGDVYISPRAKSNPRATDDFDLTSKVQEFLESKRKVFLILGDSGAGKSTFNRALEISLWDKYKVDGRIPLFISLPTIEKPERDMIAKRLRQANFTEGQIRELKLHREFILICDGYDEIQETRNLYITNQLNQSGGWRVQMLISCRTEYNSIEYKDCFQPTERNNGGDGELFQEASITPFNENQIRDYIDQYVRLEKPTWGSEDYQQALKQIRNLQDLVKNPFLLKIALEVLPQLFNTNSQLSKASITRLHLYDEFVAQWIKRSRKRLIEINLNSRDKEVFQRMNDSGFKGHGIAYFKELVTAIYDNQSGNPVVNYLEYRDRRTWKEEFFSDRDGKRLLREAIPLTRNGDQYRFIHKSVLEYGIALAVYDPNERNENTEPMPAVSRRGSTGSALSFEQPSKESTSTANEDVLLNSPLGKKTLVDEPSILQFLSERVKQQPIFKDQLHSIIERSKTDKSVRIASANSITILVRAGVQFNNADLRNIKIPGADLSFGVFDSARLEGADLRKVNLRNVWMRQANLREAQMAKVQFGELPFIKEGYDVHSCAYSPDGKILTVGLSNGYINLRETSSRDIIRILKGHSRHVWSLSFSMTGNRIVSGSEDKTIRLWDVDNGDCIRTLLGHTSAVRSVAYSPKGTRIASGSLDKTVRIWDDVTGECIFTLQDHNERVMSVAFSPMGDRIASGSKDKTVRLWDADTGDCVRTLQCHTSCVKSVTFSPKGDRLASGSDDKTVRLWDVDTGDCVRSMQGHTSNVNSVAYSRKGDRLISGSDDKSIRLWDVGTGECLNAFRGHSHNILSVAYSPNGDQIASGGVDETVRLWNVDIFDYTYTLQAHRDSVRSVAFSSRGDQIASGSMDNTVRLWDVNTGDCLRTLEGHTGPVKSVTYSPNGNRLASGSVDKTVRLWDVDTGECLNKFEGHNFDVQNVVYSLKGDWIASASRDKTIRLWDIDTGKNIKTLLGHTGELRCIAISPKGDRITSGGSDKTVRLWDVDTACCIHTLLGHSNNITSIAYSPKGDQIASGSFDRTVRLWDVDTGNCIRILQGHISDVCSLAFSPNGDRIVSGGDISMRFWRVETGECLATISSFGGEVFSIDWSDTSDDQYLITGSDDNSVRRWRFVKEKDEYKAILCWNSPHESLTMYDVSFEGVQDLSHQNRDLLIQRKGMSLVNSLLDIFRLASSSRPTLAPSSPLTLAPSSRPTHARQNSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N270</accession>
    <name>A0A9P6N270_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Transcriptional regulatory protein dep1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_000227</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000104">
        <property type="protein sequence ID" value="KAG0022455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N270"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1500">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013907">
        <property type="entry name" value="Sds3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23030:SF42">
        <property type="entry name" value="CHROMOSOME UNDETERMINED SCAFFOLD_90, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23030">
        <property type="entry name" value="PCD6 INTERACTING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08598">
        <property type="entry name" value="Sds3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01401">
        <property type="entry name" value="Sds3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="602"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="34"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="118"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="128"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="144"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="161"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="188"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="216"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="263"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="288"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="329"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="359"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="384"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="624"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="668"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="721"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0022455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="721" mass="81483" checksum="A6948E3AAC6420AD" modified="2023-09-13" version="1" fragment="single">MLEASSLRSRKHSSSSTDAKSSNNILSKEKTASIMANDSETSLSGSSEKVSGQGTNFNSTETESVGPDANSNEDSDVEMKDISPSRPQEQQSESEQKQQPRSQSHSTTSTPREKLSAEDLNGGLLDGALDDIDDDEDRDTEDTEGAHAEHEGENGDGGDDEKEKDSVDTHDELPTGDIDEASTQQSEDRDDGEGDVTMADPDDEAEDEATPATHTEDEEGSEMPEEEEEEGSHIEDEDEDEEGEVEDAEDEDEDNVEDEEDEQPSKPEVKKDLASYSQKAILNRPQIIEEELKDSGDELSDLSEFDDTDDSDEDDADGSTSSNKAKVGSNSTATNASTNARPVPGGGGRKKSLRGSSRGPKEQEEKSTKGANELERENQHPEDKESESEAVEEEEVAEEEGKADGEDDAEEEDIEKKQKHMDALDALTTIEVEFASLRDKMYEERMLELDKEVEMINDGTHPELSTLMREIEEKREHRLRIAKAWRTHMGEIAQYEFEVKEYQAHCTFQSQKREMRNDITSEIGKNKRKLILELARPPSSSTSSDNYMRTWIPDKLTLVRARKHRRAEANELRMIKERYGFPASTRLRTINTSELEEDLGAMGLSKPIPQPNESSVGENGPLGQQQYRYQQQQQQQQQQHHQQLQLQQQQQQQQQPQHQHQHQHQYHQQHQQAQLPYYQQHQHQQQQYPHQHQQYQQHQHHNPPHYGRSQGPMAAAPRPGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2M8</accession>
    <name>A0A9P6N2M8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Choline kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_002251</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the choline/ethanolamine kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000155">
        <property type="protein sequence ID" value="KAG0021512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N2M8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004103">
        <property type="term" value="F:choline kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004305">
        <property type="term" value="F:ethanolamine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006646">
        <property type="term" value="P:phosphatidylethanolamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05157">
        <property type="entry name" value="ETNK_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22603">
        <property type="entry name" value="CHOLINE/ETHANOALAMINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22603:SF93">
        <property type="entry name" value="RE24176P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01633">
        <property type="entry name" value="Choline_kinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="515"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="574"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0021512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="660" mass="74097" checksum="34867C0541311BD2" modified="2023-09-13" version="1">MYDYMENNTLITSDPSSPLRVQTSLPPEQPVHDGGCQSPEEPQGLALEVESSWQEEPVRLPAYTPSTAESEASRGSPPTTPVDDPIHYAPSKKHFGFSRRQSIASSIFPWRKHKPAVFHQYAPHHPPSSKRASFARLKVLPVTRPESVKHLEDEELDLLNLDEDQLAKRVLELLHLMNIQDWTDVIDHHSLELFRISGALTNCIFLVTGPPRVVPAVTTSSTFLDKDSDEPVLTTKPRKVLLRVYGVGLEALISRNEELYWLRNLSTMEIGPSLLGIFKNGRFEEYVDSTTLTKEDIRNPRTSRHIAHRMCELHNIVNVFPPPEGTIPKSQANIIKWIPLAREAIEKICAEDPAKRAIINEFDFEKLLREFDEIQLELATVHSPLVFAHNDTQYGNILKTNDESGELVVIDFEYAGYNTRGFDIGNHFCEWTADYHSERPSVLHPERYPTKAEQFNFLEAYMEAEIAMRGYHLTAIDITKYAKKRRSITNAIASGFSKATLSALQATSAVLRRKHSGDALKEDDISGSAPNSSGNTTPIAVNIAEASTNINNTTFVLTDGSGLALTLSNTSANGKGNGAIESNRSMPRSRRGDGSGGVSKAEVLESMYNEVNKFALTSHIMWGLWGLIQAAQSEIDFNYFEYSMQRLSEFRRRREEFMAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2V5</accession>
    <name>A0A9P6N2V5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_010163</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000068">
        <property type="protein sequence ID" value="KAG0023182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N2V5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055105">
        <property type="term" value="F:ubiquitin-protein transferase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019516">
        <property type="entry name" value="Glomulin/ALF4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15430">
        <property type="entry name" value="GLOMULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15430:SF1">
        <property type="entry name" value="GLOMULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="571"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="571"/>
            <end position="584"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0023182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="627" mass="71946" checksum="4599B54DFEB1DB69" modified="2023-09-13" version="1">MDEETPREKMISSQEILSTIEWPDVLQDHNIALEVIGLFDTHMSIILEEMMKIKSKKFSRFLKDVVLTIARPIKAIHRIKEYIAAEPTSELARNVQNDQNIFEAFEERISCMVNDLVSKVVAAWGDSQIFQLRLSPELDNEVNNQHYLLVYLILLLLDQWVAPEEMEASSTYFEYTNPKYRKFSPRGPNATPAPKKDIQTSLRHMKSMMVYFLALFKVFSTGADENDDSYDEEALLEDNYPLSETGITTLVSGMIYAMINPTQLSSTYTLPLTLAQDWVFTTAGGLASGFLTSDDSQLAMADKGLLILLYAIDRTPLNEFKMETLDYCTMDSSTDRMGLFQIFQVMVSFAATCSSSSHRFFCFQALDRLVQACEDDVKMYLLEQLVSPKCPYETMRAAAVNLVKATVERAFLNLDQARKENTEKIRTDTIGSDASSLAQVKSPFASPLLLKTFLPSIWRFDVKAFERSPLNSEDAWIERYDMLMHALNFYLFLLMRDSREDNLTEIWLVSTIQGTHKEFVEPLMERILELKEDYIQRLVQAEADQDAVFDDDFDSPMHRIKSKNGVVDFDIDMDSEDDDDDDEEATSKVKKPKDTVLDLNQKMMKVEIMDELLERIQELTSPLIQDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2W4</accession>
    <name>A0A9P6N2W4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Arf gtpase activator</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_001731</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000140">
        <property type="protein sequence ID" value="KAG0021772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08204">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000252">
        <property type="entry name" value="ARF GTPase activator (Csx2)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.150">
        <property type="entry name" value="Arf GTPase activating protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045258">
        <property type="entry name" value="ACAP1/2/3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037278">
        <property type="entry name" value="ARFGAP/RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001164">
        <property type="entry name" value="ArfGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038508">
        <property type="entry name" value="ArfGAP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004148">
        <property type="entry name" value="BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23180:SF160">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN EFFECTOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23180">
        <property type="entry name" value="CENTAURIN/ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01412">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16746">
        <property type="entry name" value="BAR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00405">
        <property type="entry name" value="REVINTRACTNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00105">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57863">
        <property type="entry name" value="ArfGap/RecO-like zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50115">
        <property type="entry name" value="ARFGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PH" evidence="6">
        <location>
            <begin position="498"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="domain" description="Arf-GAP" evidence="7">
        <location>
            <begin position="677"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="79"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="377"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="444"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="632"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="914"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1163"/>
            <end position="1190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1226"/>
            <end position="1254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1317"/>
            <end position="1344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1360"/>
            <end position="1388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="95"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="377"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="455"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="632"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="655"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="925"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1163"/>
            <end position="1179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1237"/>
            <end position="1254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1361"/>
            <end position="1388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0021772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1388" mass="151415" checksum="9AFEB1146CA5BD14" modified="2023-09-13" version="1">MDLQPLVGENRASEQGLANQTYTWTWSYPLKDQVENPIDRKAIFADPSSGNIVVLSQFSLWIYTAEADHHARLRYSAGQATSASSGRHWRHASTSERFTSSNNRSQSFHTKGPSIPSSHASLPSLPDATIGAVGQDASGPLTGSLSNLNPTALVTDTEDGPLFRATVLECENNIRDMKASTKKIIKAAQTLLESRKSLVIAEETFVKELEGFKPAEPLLNNYLRPMTQSYVARSEFLGNQMHSLLIDPLTRFYVNDIKAAEVHRKAFEEESKEYYQALSRYMGMKQDNNRKKSEADAKYEKKRRNFEIKRFEYWCFLLDMRAGGSKSDELLYHLTNYSEKHCRSMMDLALLAEDMKIGLDHIANDLLESQKRAASIRKERQERKKELTESCDESLTSIPHPPIIQKSGSSQVPSGPTPLFPGSEVLPESNSDNLASIQEVFDDVHDGSTPTDQRTLSGSSPTTSTTLGSTQLNDSSIPKFSGIRDLEHQDIDANLAHGRRKEGFLFATNRPSSHNNSTVLEKSSVNWHKYWCVVSEGLLHEYSHWKKGVTMLHNEPINLKLSTVRPCRNQDRRFCFEVITPKYRRVYQATSAEDMNSWISVISNAIQSLLNGTSSLNLDIYPPGKDGKSLASDISNTSWNGRTSMDQPVSQGQVSSTNGSSEFSSTVESADTEHLGTRLLKVMREAHPSNNFCAECGAKSPDWCAINLGILICIECSGIHRGLGTHISKVRSFTLDTTSYTRDLFDFIRSVGNEASNKIWEANLVQTPQEGTDKVFFRRPLVNDSREYKISFVQKKYVEKAFVRKFHQTEGTEPEDQAILATKALFQAVVSNNIVDVIAAYSAGADLNAIEESELENEIISSGSGDVAMGSDGTAESLLEDGQTQSNLEGLSLNSEEESRLSRSTIASSILNVPSATDSGHESQGDQQPPSDNPDSSLPHKTSDNRNSSFMVMQTSPLLLALRNGVPFSLDDQYEVYPMAEFMLQNGASSNLSMEVRLIEDDAEGSGSGSVILSEGASDACATDDNQPTLQQGGLLIQTNGSSSNDNGWDSAHVDPEDIRNFQQRSNRRSLGQVVNLRGEGGVSAMEYLRAKSAARGEHMAGSPPIGGSNDSNATFTTPGSVSPSGAVSPRLRSQYATLSVGSVSAPTSVISFPSGTYSTTVFRKQQPSSKQQDISSLFQKRRESDSGIGPAAFAAGKAAESDKKSGTYKLQSAALVPTSLTTHELTQVQTTPNSHGHSHSHGHSHSHGHSLLHHSTIRAHKVKATLSKSLRLSAAYIKNNMMKEEKEISLPVISSPTIIPSASPSSSATLIKQKEATTTSVGTTQDSPSASVTAKSSEQSRDSISLTGSYVFLHKKGTIPTSNVSSSPVSNSNPDPPSSSTATNPDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3P8</accession>
    <name>A0A9P6N3P8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">SCF ubiquitin ligase complex subunit cdc4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">CDC4_1</name>
        <name evidence="6" type="ORF">BGZ80_000174</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000103">
        <property type="protein sequence ID" value="KAG0022472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3P8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010992">
        <property type="term" value="P:ubiquitin recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22147">
        <property type="entry name" value="F-box_SpPof1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19849:SF1">
        <property type="entry name" value="F-BOX_WD REPEAT-CONTAINING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19849">
        <property type="entry name" value="PHOSPHOLIPASE A-2-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="F-box" evidence="5">
        <location>
            <begin position="462"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="737"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="847"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="887"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="929"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="969"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="196"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="256"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="318"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="551"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="22"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="48"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="81"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="201"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="592"/>
            <end position="605"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0022472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1134" mass="122784" checksum="F04E5D996437A287" modified="2023-09-13" version="1">MDPNRPQRVHSVQSPPTPPSIPQSTSSTASTSTSTRASRSGHRPATASHYTVHTDTEMITSKHTTDHGSSSVHPSDRQPSRSRTSSSSSSTTPSHRRQPISTTFSLAPMTTTTVVTTTTTTSTEYPPLYFKPPPIPAHLDPKIFPLADTPTPPALKKFCFDLNGQPTFFRENQEGEHTMGQLEDALFNLSASAHQRALRSASEHQKSDSIQDDQKATLNDQGDVSVTREIIRGKGNDRSTTTTITQKSVELPQRGLAPHPAWRSRERCRAKKRPASPITPVGSVDVAIPQSLSSSSLHSSTASIGTIQKTAEHADASFLDRSSPPHKKSKRPWTNVPHIQGSEVSSNGTVTRRRFKTAPTSFHHNQEEENGAATDALADEEETYMSDTDGNDDGQDEMEVERSLQQSGIHHTPTLLDLPNLIATFDALPSSLQSYMLFHLLRRSPAPTLQFVSSVILATMKQDFLSLLPVELSRNILRFLDGRSLCKAAQVSKQWRVVVDSDAHIWMHQFQKEGFVLEEREEEEAFAQRLGIDGHYGVRPNYQERKLLAKRRITKGKGRPSQTIVRPADLPESPLYPNDVTMLGEDDVENPLESTSAHQGSTNKSHGWDSDTAEEDGDTKEETFMTPDAAPPSPTTSHSGRFNDVDSEDELMEQDPIDEPFGPMPPSTGHPYKALFRRHWIIRQNWSKGRAKYIQFTGHSDRVVTCLQFDSEKIISGYDDQSIHVYDTVTGNRLKKLDGHEGGVWALQYRGNTLVSGATDRTVRVWDIEKGVCTHTFRGHTSTVRCLQIVMPVNVNKDPHGIPKYEPEFPVIVTGSRDSTLLVWRLPDPELNGHIPPTDNSWLLHTLVGHSQSVRALAAEGSILVSGSYDCTVRVWNICTGAAVHQLRGHTQKVYSVVLDTERNQCMSGSMDAFVRIWSLEDGSCLHVLEGHGSLVGLLGLNANHLVSAAADCTVRIWDPARGVCLRVLAAHAAAITCFQHDGNKVISGSDGNLKMWDFKTGKFIRNLLTGLGSVWQVKFDERRCVAAVQRAGANGANGATYFEVLDYGVYGIEEPLENAPPLPDESVEAGAPRVGAAVGGGAGAGAGPGVGAGIGAGAGVGAGIGAAGAVAGVGAGANGGAAAAGDGAPAAAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3U6</accession>
    <name>A0A9P6N3U6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BGZ80_011587</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000095">
        <property type="protein sequence ID" value="KAG0022642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3U6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18579">
        <property type="entry name" value="ABC_6TM_ABCC_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000997">
        <property type="entry name" value="Multidrug resistance-associated protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000163">
        <property type="entry name" value="Multidrug resistance-associated protein member 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044746">
        <property type="entry name" value="ABCC_6TM_D1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF447">
        <property type="entry name" value="MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040356431" evidence="10">
        <location>
            <begin position="17"/>
            <end position="1136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="83"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="180"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="213"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="736"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="775"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="1"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="273"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="857"/>
            <end position="1091"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="506"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="687"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1100"/>
            <end position="1136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="519"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="693"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1106"/>
            <end position="1123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0022642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1136" mass="126017" checksum="A16A7DC6DC09B239" modified="2023-09-13" version="1">MYAMGLLLTSLGSSIAIHQLYSQCNALGIQVKASISVLIYRKTLVLARIRDGAEVINIVSADVARIVEAVTNFHFLWSSVVEIIIILVLAFPTLGWAAALSAIGLVVAVLPIQAYLGRIASDILIKQTVASTERVHLTSEILTAIKLIKFSAWEAPFQDRVNQTRARELHLLKRYLQVKGLNMTVVFVLPAIITAVSLVVYNARRNGPLESSVVFTALSIFNTLQQPIFMLPIAVKSTSGARMALHRLDDYLTQPELEPLEEHPLGEGGDVALELQDGEFTWDDGNSGPVLSGINLKIKRGEVVAIVGDVGSGKSSLIAALLGQIRQTGSGPKLKLYGKSSYVPRKAWMINANIRENIVFGKDFEQERYDTVIKVCALERDLTLLSHGDMTEIGERGSNLSGDQKQRVSFARAVYQKSDIILLDDPLSAVDQNVGKHIFDQCIRGYLSDRTVIIAIHQLEYLHRCDKIVMLRDGKIAYQGSFEELMSNEPSFNTLINTYVSSEDDECYEGDASTDGESKSQTTIDDSASANASNLPNRGAERRRYTLPPNTWIGDTPGTTSISSQKHDTLIPQEQYNQLNRLLTRASRNSILNSTLRDQKNLHFISHADDVDGFSLDTDFSRTVSRNELAVHSFPENGLYESRRDRAKGRHSITEAPIRRSSTVSYAFNFGAMNEDEWATVTRDSYEPKDLDESTSDDESSAEEEKVGERIVQDNIMDELGLTDYIKYFRVGSGTLVTLLLIFPFLVAHIIRIVSNFWLRLWVPNNLHSSDSFYLWIYAALITVFALIVLTRGFWFAHEATYKSKELHARAFKMREIQAQTSAVGHLDYYGRQIEPEAPAENLKTQPDESWPREGRIDFDHLVLKYGKDSPPALRDVSFSILPKEKVGIVGSTGSGKSTLLVGLLRIVEASRGTIYIDGIDISTLGLNDLRTKVGVISQEPVLFVGTIRSNLDPFGQHEDNALWRALDAVHLGDKVREMPLRLDSSVVENGKNFSLGQRQLICIARSLVIGSKIIVLDEAAASMDMVTDKLLQEATKENFADCTVLTIAHRMNTIIESDKVLVMDGGVVAEFGEPYKLLQNPDGVFARLVSHTGEAASKKLAMTAKDAHNTRERGQVLEEENRASGSEDAISSHVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3U8</accession>
    <name>A0A9P6N3U8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Phospholipid-transporting ATPase</fullName>
            <ecNumber evidence="17">7.6.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">BGZ80_008687</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12 17">
            <text>ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.</text>
            <dbReference type="EC" id="7.6.2.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out) + ATP + H2O = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66132"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:66133"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="16">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endomembrane system</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 17">Membrane</location>
            <topology evidence="1 17">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 17">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.6.2.1" evidence="17"/>
    <dbReference type="EMBL" id="JAAAID010000048">
        <property type="protein sequence ID" value="KAG0023649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140326">
        <property type="term" value="F:ATPase-coupled intramembrane lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045332">
        <property type="term" value="P:phospholipid translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000014">
        <property type="entry name" value="Phospholipid-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006539">
        <property type="entry name" value="P-type_ATPase_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032631">
        <property type="entry name" value="P-type_ATPase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032630">
        <property type="entry name" value="P_typ_ATPase_c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01652">
        <property type="entry name" value="ATPase-Plipid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092:SF218">
        <property type="entry name" value="PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092">
        <property type="entry name" value="PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16212">
        <property type="entry name" value="PhoLip_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16209">
        <property type="entry name" value="PhoLip_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 15 17" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 16 17" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 15 17" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 17" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 17" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="534"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="796"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="823"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1421"/>
            <end position="1445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1457"/>
            <end position="1475"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1496"/>
            <end position="1523"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1543"/>
            <end position="1561"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1568"/>
            <end position="1588"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1608"/>
            <end position="1629"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase N-terminal" evidence="20">
        <location>
            <begin position="518"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="19">
        <location>
            <begin position="580"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase C-terminal" evidence="21">
        <location>
            <begin position="1390"/>
            <end position="1636"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="286"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="389"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="881"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1659"/>
            <end position="1725"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="18">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="25"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="71"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="123"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="155"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="286"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="319"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="18">
        <location>
            <begin position="1689"/>
            <end position="1703"/>
        </location>
    </feature>
    <feature type="active site" description="4-aspartylphosphate intermediate" evidence="14">
        <location>
            <position position="959"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="959"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="959"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="960"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="961"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="961"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="1040"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="1082"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="1104"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="1140"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="1227"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="1228"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="1229"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="1338"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="1344"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="1364"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="1367"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="1368"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="1368"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00034036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00049128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU362033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF16209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF16212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAG0023649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1725" mass="190313" checksum="675A801FE0CBEDF9" modified="2023-09-13" version="1">MTLPENPPPPSPERPHQSDQLPIGSAASASSSTPLVTSTSSTSLNKSLSPTSTSQLRTRPRSGSLPMGHSYQRTQGASSSLRLEVLPDDRSGLSSTSSSTPFHNAPRGGSSTVSTPSKLRHVTSTSGFGSSSSSSGRSRSGSITSPRPANLSLLAPTSPSISPIGASSPLSSSSGSTVIGQRPRSGSSSPLPNNLPERRRSLREDETDAGLVKAQLNLSLDKGPPQSIETWDPVIPDILVQDEDPDEPNSTTSMSEHHDEEEEKIVSQYQVLNLIIPDISEAVAAAEQQEQLESELASDAAQPTTSQSTTSPTLSGQPISNSRLNPPTSSVPSTRPGSPLLPLSNSSSISNLNLAAAGGSIQSGSISPVPPATLSARFRLPFSSKAFVPPSRPASVHQPSQPPAETPFAGSSTVLGINNPMQSSANGSSAIRSSIFDYRLTNLLFGGSSIAPSVRSFDPTRASIDGEENRRELYEVEFNVPPDPTQEEARRLDRTTWGRIRKVFRAGFPGRDLDPRTRKPRYKYPTNNIKTTKYTLVTFLPVNLLFQILPLTLVLTITAIKDALEDYRRYQQDKRSNSLECTLIKDGELIPIKSKDIRPGDVLKISKNDKIPADVVLLSSSMDEGACFVETSELDGETNLKRKAALTITSGLTRLEQISRLTGKITTEMPNERLSRLDGRIKLRYDGTDFNVETLDDEKSGGEFTNILRGTSSSSLISSGPSISFSRGQKNTAGGPKLDEVVPVTMTNVALRGCWLKNTEWVYGVVLYAGVDTKMMRNLKNTGLKFSTMETKLNRMIVAIFVFNAALLIASMCFAYLMNFYVVYTFVIPISVFISVELCRVVQALWMIWDEEMRSYTEGPLSQAELEEIAMEQGDAAAADAAAETDALPTPKKREDDLESNVMSSAINDTKPKSKKFWKKTNFGFLKRKKKAPKNWTRMHVRNSNLNEDLGAVEHIFSDKTGTLTRNVMKLSKWHIGGRTFHELQQPGSLGLRMRDPSISDEEYDLLMAFCRNIVVCHSVIPCEDSNTGELLYEAQSPDESALLEALRDNGVVLKAKTKDSVTVEIFGLITETYKVLKVLEFTSDRKCMSVIIDTPQGIQLFCKGADNVILARADTGENDPLLMRQLDGTVRRFSIAGLRTLMLAWRPLSPEEYRRFDETYSKAECHIGDGEDGSEDREDMIRSACETIEGRLRLLGCTAIEDRLQDQVPETIEYLMDADIKIWLLTGDKQETAINIGISSRLISPAMKILVLNVKVERDCRLVLEYFVEKMKERERDEERYLQEYQQSSKPGIELPEKDRYALVVNGESLAFVLGNEIFEDMFLRIGTSCHSVICCRVTPLQKALVVKLVRKKLHKVTLAIGDGANDISMIQAAHVGVGIEGMEGAQAARSSDFSFKQFKNLKRLLTIHGRYSYLRMSKIIFFSFYKSICLITVQFWFGFMNAWSGGALYDENFLTLWNMVFTALLPITTACFEKDVEEESIGRYPKLYKAAKDGIFWNTLTVAGWGIASFWHSGALFGAIYGSVLHGVVGGDSAVMDESMLSFYAGSLVLITVTLKMLLMISHYTLPIFLALGISMAGYMIVFIGLEVVGLLEEGVFAGLHRLPFYYLGLILIPIACLLPDYTLAYFRRQYTPSDAQIIQEEQRLIKLKKLVSSAGHNKNGKKARNDLEDQEAMVELDSPIKRTEKEDDEDEDEDGDEEGSYEGRQEDGGSKSQGLMASNEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N423</accession>
    <name>A0A9P6N423_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Mitochondrial import inner membrane translocase subunit tim23</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">TIM23_2</name>
        <name evidence="5" type="ORF">BGZ80_011141</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000086">
        <property type="protein sequence ID" value="KAG0022792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N423"/>
    <dbReference type="OrthoDB" id="159299at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005744">
        <property type="term" value="C:TIM23 mitochondrial import inner membrane translocase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045238">
        <property type="entry name" value="Tim23-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15371:SF0">
        <property type="entry name" value="SD19278P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15371">
        <property type="entry name" value="TIM23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02466">
        <property type="entry name" value="Tim17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0022792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="205" mass="21289" checksum="27769900C282C20F" modified="2023-09-13" version="1">MSQQYNSNIEEEESFAPIYANQEDFNPSETVSSFLNTTYDPARLHPLAGLGGGLDYLNLDDDPGVLPGTQGGLLPSRGWGDDLTYGTGLTYIAGLSLGGAYGFYEGLRSSPSPAFKIRLNTVLNSMTRRGPFIGNSAGVLALMYNGVNGAIGKARGTHDPLNSVAAGALTGALFKSTAGLRAAGSAGGVCAVLAGIWAFGREYVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N442</accession>
    <name>A0A9P6N442_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_007122</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0585 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000036">
        <property type="protein sequence ID" value="KAG0023936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N442"/>
    <dbReference type="OrthoDB" id="10258744at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010342">
        <property type="entry name" value="DUF938"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20974">
        <property type="entry name" value="UPF0585 PROTEIN CG18661"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20974:SF0">
        <property type="entry name" value="UPF0585 PROTEIN CG18661"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06080">
        <property type="entry name" value="DUF938"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0023936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="250" mass="27924" checksum="9C9E9F6B94E937EA" modified="2023-09-13" version="1">MTSNSQTNLPSGSTATPVGNTFNHNQNMSEFVQVDRKVFFAAADRNKEVILDQLRPVLDKARLVLEVGSGSGQHVYRFSKDYPEVTFQPTEYDTALLPSIDAYTNDLNNEGHHINPALELDATKPEHWQRVVEAVQPEQQSNGGGCFDLVMTTNVFHISPWVVGQSIVRGAGQMLKSGGSLVIYGPFKKDGVFNTESNREFDATLRGRDPSWGVRDVEEIEAVAKNDANMKLDRIVDMPANNYMLFFRKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N445</accession>
    <name>A0A9P6N445_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">rhizopuspepsin</fullName>
            <ecNumber evidence="3">3.4.23.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">PEP1_1</name>
        <name evidence="15" type="ORF">BGZ80_006290</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of proteins with broad specificity similar to that of pepsin A, preferring hydrophobic residues at P1 and P1'. Clots milk and activates trypsinogen. Does not cleave 4-Gln-|-His-5, but does cleave 10-His-|-Leu-11 and 12-Val-|-Glu-13 in B chain of insulin.</text>
            <dbReference type="EC" id="3.4.23.21"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.23.21" evidence="3"/>
    <dbReference type="EMBL" id="JAAAID010000031">
        <property type="protein sequence ID" value="KAG0024065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N445"/>
    <dbReference type="OrthoDB" id="15189at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.70.10:FF:000115">
        <property type="entry name" value="Lysosomal aspartic protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF1">
        <property type="entry name" value="ASPARTYL PROTEINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="9 11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="15" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 12" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-0675">Receptor</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0732">Signal</keyword>
    <keyword evidence="15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040481080" description="rhizopuspepsin" evidence="13">
        <location>
            <begin position="21"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="14">
        <location>
            <begin position="87"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="105"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="289"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="118"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="325"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0024065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="402" mass="42245" checksum="C12C0B1ECD5253BA" modified="2023-09-13" version="1">MKFTATILSLAIAALAFTEAAPTGPAHSGHEIPLVRKENHKKNFRSAMSKLANRYPELNLSVPRPIHSDAVGVGKVPLTDVGTDSEYYGSVSVGTPAQTVRLDFDTGSSDIWFPTTSCTTSACKSHKQFNSAKSSTYKKDGRKWTISYGDGSSASGILGSDMVSVGGVSVRQTIGLATSESSQFAQSPEDGLFGLGFDTIESVQGVKTFMDNAIAANALKKPVVSAYLPSVRRNGGKGGAYIFGDIDTTKYTGNLTYVPVTRKGYWQIAITGASYNNKSLKQSSQGIIDTGTTLIIIGTSAAAAVHKNIKGAVNDAEVGGWTVPCSIANSKDTIGFTMGGKSFKVPVADLAWSPVDSAGKTCYSGVQGGQDGLWILGDVFIKNNYCVFSQTSNPSIGIAPLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4K1</accession>
    <name>A0A9P6N4K1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RSE1/DDB1/CPSF1 first beta-propeller domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_009674</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000060">
        <property type="protein sequence ID" value="KAG0023362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N4K1"/>
    <dbReference type="OrthoDB" id="20774at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018846">
        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050358">
        <property type="entry name" value="RSE1/DDB1/CFT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10644">
        <property type="entry name" value="DNA REPAIR/RNA PROCESSING CPSF FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10433">
        <property type="entry name" value="Beta-prop_RSE1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RSE1/DDB1/CPSF1 first beta-propeller" evidence="1">
        <location>
            <begin position="66"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0023362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="970" mass="106773" checksum="70A6CBFD9952FBA4" modified="2023-09-13" version="1">MDYSNIRVYAKHLQPPSVIHQACIGDWTRRYNGLGNDLEQESAQVDVVLGKVRRRFVADETDSESRPTGTLNLLHEQPVFGTIKDIKALHCNFEPEGEINLGTSMEIDQLADHPRLGYLPKGASPTVLVVTSDSGVLSFLTFHYEESIPGAAEHGSFHVLKEIVIAEPGFDYSQAGAKIAIDPTSRIMAISALQNLIKLVIIRNTKKSQFDPVERISEIDIKGTIIGMDFLTPEPKDKTDVAILAVLFHNKDTSKYHIATFHIGLQNRLTSPLSIQVGTSQLVTNPLKSVVLLKALPNIPRSMVYIDEEKITLVTVEAPTDSGTTNISRHTHHSPLQLLKRESSEVPSEGVTSLSIGDVYPLISACATPPPSPYAASDQTLYLGSDTSELYRVNIQHLTYTMQFELVTGDKPVGNMMQVLARRQFTTQSLFSEMSQDIVLNTDYLIYSSDYGDSGILGIKEEEEGIDLFAITELQNSSPILDFCVREPLLPGRDSLYACSGMKGEGAVRRVRYGISVESSGNSGNDFFSGATGLWSVKENRKNTFDSFLVVSFIQSTKVMRIEDGVKEGTLALGQISSGASSLIVLELAKETAVVGDQFLTHSLKTIATRSLKAEPTTIHCWAQDPSFEESMEGDVNLSDFYCCVGTLEPAVLVFQIATDDIREIYTESLSQTGFESVTIPHSICILRSRDGRGKVVVGLRDGSVVVYEWNRPCKEDASPALRVLSSPRLFKIGIRPVKCVFSDNVLSRTLILSDDLWLANFDLNLEIKPVLFDSEVTQACSFESRDDNQLSKPGFVFIVDHHDIQLVTFEGAAKYNHQALVLGQTPRRILDITSKELLLVASVGDGFPFAESTLHLIDPDRVSTEAGAEKQHIVAEFALKQGEAVYCLAEWKIPRPNKSDAVYICIGTGLFSPTGSEVSAAAPKTGRLVVLSVKQSKKADRKSRKFELDLRWAMAMPAPVFAVSTFMDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4P6</accession>
    <name>A0A9P6N4P6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_008222</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000044">
        <property type="protein sequence ID" value="KAG0023745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N4P6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="100"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="155"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="509"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="15"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="155"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="178"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="237"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="286"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="305"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="366"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0023745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="625" mass="66655" checksum="853CECF59BB9ACB1" modified="2023-09-13" version="1">MDVVSPSPVNGSGFGPTSSPGPGLNSSPAPGAASSPEPGVNSNSNSNSGPLTPITNKKPAALRNLQPRAAAALDFNDNVDSDEEFGGLLSEDYKAQRKTTKDLVDFLNSGPPEPPPGTDLRKQQQQQNQKSNVTTGGDEEKKKWFFLQKLRSKKTNSGIGNVSSISLGSGNKRGSAMANGTSSNISSMSGMTLGRGKNGDVPTATLPNGKKYIMISVKEPDTGSINGSGGVVGSLPSPSPSPSPSPSSPGASALSIAASKRTSIMSSFREDGSSAGLGDARRRSAIPNSGASESSLLLNGGVQRSPSSKSRGESGSIGSMSRNGSKRTSRVTFSTPRAPSTHLDDATVSEALEQRIASYKAKQQQKDSSTGPSSALVSTSTSMQDFPEITLPKPVSRKKVRHVQIQTQHSIMRPMYTQTEPYESLVQDVKVKDWSTQTTSTESISGSTEVGTSTIDLKDSIISSAFLPPPTKKDGISASTSVGSFASFATATDAETIPSPTTVSPQDELAQLRQQNALLQSQVASLQRELAAEVRARTRTTAAMQDTRVKFEMLSEMAFQKLKEMIFHRQVLDKEMQELRAKVDMQSEANVIQQGEMLFRQEQLQLQMQMQMQQQQQQFHRMSTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N500</accession>
    <name>A0A9P6N500_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA(Ile)-lysidine synthetase</fullName>
            <ecNumber evidence="1">6.3.4.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_006486</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>cytidine(34) in tRNA(Ile2) + L-lysine + ATP = lysidine(34) in tRNA(Ile2) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:43744"/>
            <dbReference type="Rhea" id="RHEA-COMP:10625"/>
            <dbReference type="Rhea" id="RHEA-COMP:10670"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="ChEBI" id="CHEBI:83665"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.4.19"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.19" evidence="1"/>
    <dbReference type="EMBL" id="JAAAID010000032">
        <property type="protein sequence ID" value="KAG0024042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N500"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032267">
        <property type="term" value="F:tRNA(Ile)-lysidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01992">
        <property type="entry name" value="TilS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01161">
        <property type="entry name" value="tRNA_Ile_lys_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011063">
        <property type="entry name" value="TilS/TtcA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012094">
        <property type="entry name" value="tRNA_Ile_lys_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012795">
        <property type="entry name" value="tRNA_Ile_lys_synt_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02432">
        <property type="entry name" value="lysidine_TilS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43033">
        <property type="entry name" value="TRNA(ILE)-LYSIDINE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43033:SF1">
        <property type="entry name" value="TRNA(ILE)-LYSIDINE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01171">
        <property type="entry name" value="ATP_bind_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal" evidence="8">
        <location>
            <begin position="1"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="72"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0024042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="601" mass="68398" checksum="B5D072B8098DCACD" modified="2023-09-13" version="1">MALATLLARHYQSQKINDRTVSLHALIVDHKLRDNSTEEAAVVAAQVQKLNVIPHVLTLDWTTTRGNDSNDENPRHGSDTIFQKPDKTHLETKARLERYKVIAKQCHSLQIKDLYVGHHSGDQVETVVFRFSRASGIDGLAGIQGVAPLSVLNVVEGLNIRVARPLLNVSKERLRATCEDAGTLWVEDPSNQSLDYQRNVIRHYQHDVDVAAENDAQSKLYPLSTAAMLKFRERINQHRQFAWEQVKPWLKDIHFDTENGVCHIKLQTTESATASGNIEWLRESQNHVASRLLSFLVRWVNCKDHAPRLDDIQILLRRLRHPVVTTTTPSSTNNGLATVERENSSISTVYRRKKTRVSKYKSSQQLTEALLQDKDNLDVKAQQQQPIHVAGVLFSPPRKTKGISNHWTISRQPMSYAEQMSATVSVPAIFQDVLENKNEIDGQNRITDLLWDQRYFIRIDGYSLLDWNRRAQVQRRICIRPLAPSDIAGIRQTLDKVGGPEEDLKKLNRWMEDIPGNSRFTIPVVYCVDEQQSPTMLLSQNKSADSSKSPVSETLLSLPTLGIHRESPQLKVISWFKSRDINVNLDLRSRTDDALFESITH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SQD0</accession>
    <name>A0A9P6SQD0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_008981</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010005070">
        <property type="protein sequence ID" value="KAF9991660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SQD0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9991660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="169" mass="19443" checksum="D989866034107F7F" modified="2023-09-13" version="1" fragment="single">MRPDDIHCIDTSQSKIVEGNLEVVVLFPKERRSKQRIIKTTKVWHHSVPELCPVKTYNVYRIRTSSFDKKMAHPKDRNTRFTPLMRNCQDLSLPISTDRISNHMQSVSQFIPSWDDSQKLKARAIGATMALRNGVSVDDVMVQGNWSSTDIVNEFYRLSRSTALNFTTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SR15</accession>
    <name>A0A9P6SR15_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008442</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004574">
        <property type="protein sequence ID" value="KAF9992713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SR15"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9992713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="60" mass="6032" checksum="67F1C9D10E9A3801" modified="2023-09-13" version="1" fragment="single">PLTSPLLPPAVASLLPPRRPASLPSSLPRVSARSLSPRVSASLPAPSLVLPATVTVLTSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SR99</accession>
    <name>A0A9P6SR99_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_008482</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004601">
        <property type="protein sequence ID" value="KAF9992624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SR99"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PA" evidence="2">
        <location>
            <begin position="113"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9992624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="230" mass="23765" checksum="800D6ECBE68B4D93" modified="2023-09-13" version="1" fragment="single">MEMAFNDGMDIINMSLGGGSSFKENPTAALAEKLIARGMALAGAAGNDGTDGVWMVSDTGLGDHATSVASFDNLFIYLYSFTYGGVKVPYNWSSGYGKVINLPALPIVPLIVNGTLSDGCDQSTYAGKDVKGKIVFALGDITRCKSGGRSSLASQNGAAGIISQAMGGGMDNLAGIDGFPMASIQKVDGDKMLAAWKANAKNTVTWEGKEGRFSIDNAGAPSDFSSFGLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SSM4</accession>
    <name>A0A9P6SSM4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007255</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003686">
        <property type="protein sequence ID" value="KAF9996389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SSM4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="29"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9996389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="57" mass="5667" checksum="1121FB99F0394ED8" modified="2023-09-13" version="1" fragment="single">VTKIHSTKPKSGGSAMGQEAYQDNQSVMASTATASISAPTTSGPGTMAAPVEIATRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SST9</accession>
    <name>A0A9P6SST9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Band 7 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_006812</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the band 7/mec-2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003386">
        <property type="protein sequence ID" value="KAF9998314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SST9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd13437">
        <property type="entry name" value="SPFH_alloslipin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.479.30:FF:000004">
        <property type="entry name" value="Putative membrane protease family, stomatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2090">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="entry name" value="Band 7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043202">
        <property type="entry name" value="Band-7_stomatin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001972">
        <property type="entry name" value="Stomatin_HflK_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10264:SF19">
        <property type="entry name" value="AT06885P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10264">
        <property type="entry name" value="BAND 7 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00721">
        <property type="entry name" value="STOMATIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="Band 7/SPFH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Band 7" evidence="2">
        <location>
            <begin position="36"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9998314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="274" mass="30270" checksum="D9ECA3AA0977EB4B" modified="2023-09-13" version="1" fragment="single">FSPDDENHGMYGSMMNAAGSIMGALGSIPCCICCPNPYKTVTQGHVGLITRFGKFYKIVDPGLTKINPVTEKMIKVDIKIQIADIPQQVIMTKDNVNVQIDSVLYWHIVNPSQSVFGVSNVESALIERTQTTLRHILGMRVLQELIENREAIGEEIQEVIDAPARNWGVKVESVLIKDITFSKELQESLSSAAQAKRMAESKVIGAQAEVDSAKLMRAAADILNTPAAMQIRYLETMTNMAKGSNTRVIFMPTHQGGNEMTPMQATQWEQMAKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SUG3</accession>
    <name>A0A9P6SUG3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Small acidic protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_005594</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SMAP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002752">
        <property type="protein sequence ID" value="KAG0004615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SUG3"/>
    <dbReference type="OrthoDB" id="10066125at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005819">
        <property type="entry name" value="H1/H5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026714">
        <property type="entry name" value="SMAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028124">
        <property type="entry name" value="SMAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22175:SF0">
        <property type="entry name" value="SMALL ACIDIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22175">
        <property type="entry name" value="SMALL ACIDIC PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15477">
        <property type="entry name" value="SMAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00624">
        <property type="entry name" value="HISTONEH5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Small acidic protein-like" evidence="4">
        <location>
            <begin position="190"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="211"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="10"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="24"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="79"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="136"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="150"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="168"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="219"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="231"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF15477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0004615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="287" mass="32358" checksum="68A3E7581FCAE662" modified="2023-09-13" version="1">MEDEAPVKTHKEKKDKKDKKDKKEKKDIVEKKEKKEKKEAKESKDEGEKKKSKKDKEEKPEKKETEEKSEKKEKKEKKEKKDKEGKSEKKDKKNKSEKPEKKEEDKEDKAEKKDKKDKKVKEEKKEKKEKKESKDKKGKKEKKEKKASKESSSTPEPTTSSSSSTSPTPVPAPAPAPAPTAAGQKRWNDWSQADLGDDKQTNKFLRLLGAKKATNEGDAGTGTKKGGLFGSLGSLANSSSQNTNTESAIDSMVGRKVSRDLEKQFQDGLKIRQQMKKGKSVGLGFGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SUG8</accession>
    <name>A0A9P6SUG8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_005576</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002747">
        <property type="protein sequence ID" value="KAG0004669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SUG8"/>
    <dbReference type="OrthoDB" id="2426193at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="422"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="446"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="351"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="582"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="638"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="351"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="645"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="664"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="705"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="716"/>
            <end position="728"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0004669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="817" mass="87599" checksum="6B7AF89A847F18FF" modified="2023-09-13" version="1">MAHNSSTLQIDIPQSITKNDVTPGSPEYFCPKEEASFSFARDGSQCLASPSSVTSPSPMMTPLPYKMQAPVALSPPNLQHNSRNNRDEKKRLSEYEFPSPTAKADSLHQSYLNHPFTQLRQQRLEEYRIQQEQQQQRQKISYANKYASYTNSSQPLARSHSNNNKPSTTTALSMIEKEKSAYNNGSNRNSIVSPPPPPYLYSDHGVAPLENQHRYQYQYPSPSSPSSYGHTTITPASLAWNKRKSLPAPVLTPSRPAASSFLSSSNPLMARTTRELKRHSLPVTPSAGAPQWPSAMTMTMAAVTRPKLAKTMPPQAAPISLGASTPTAVFTPRTSRLLLDRGEADSLYSYKFSSDDGQSTPRSAGSPRITPAGAGVRGSHSHFFDMHHRVGTASCVTNGSTRSQAQQFPGYWKDAKEHRMHWVFLSLGLMAAGSALWIYLMVPALLIWATALPAILAVVVGAQYAGYKWRRHQHNKAQLNSHKPSATALSSMRAASAAFTSASASAATTAVSGTATTAAPGTAAITTSAATTTLGVVAGTAVNHAHRPSHSSMHTSVGSICGDSFLEPHQPSPPNILKSQFQHQYLRSSSSSTSSSGLPTQFADGYTFHNQQQQQSGYGGNGGEGALPEYRQSWNNQRSLGSEKSLQEKDNDNGRLRTIRRQGSSSSIASSETVSSTSTASELEYARSPSSPTEAINSPDDRLGLRLGAGLELGSPASSPTQMESAEATTGGMDALASSPEALKSSDSLCSLDSTTMMAPPPAYISKKCGEVVISEKGETLSEKARSLLEGGGGLPEIAPVGDLVSEFDFDFGTIQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SUI9</accession>
    <name>A0A9P6SUI9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005529</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002722">
        <property type="protein sequence ID" value="KAG0004962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SUI9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="277"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="484"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="61"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="117"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="136"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="279"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="324"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="356"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="504"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="634"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0004962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="634" mass="67505" checksum="46407DB848BB5779" modified="2023-09-13" version="1" fragment="single">LLPESLTSVNNYAIHQEAANQERARRLSEEENMATSKPPETLSLGRMAGVRYSRSSSNGSTVDMSPTTPTTTNPYGTLPVRTPRQVTPRLSVSGGSGIYTKPQHPDEAQPLSAQVQSPGLSKLPSPLSTISRSGTRSSPPNSQQSSRRSAFGSQEIDIQTIQNIQKAPRMSSPMDYSEDLYRTEREDQQPPRAMYHQQSMDREVPEWQDEEEQPRYQPLQQPKLRDSPPMHRRSSSEIQKEQHNLQRLRIQQQAREEVYGRGYGNGYADDPEYLDEFQNRPSRQTGGFQQRATQLSPTRDYFSSTARSGSGVMRNSPPVSTQTRYEHLRRPSRDGHSLMPAPKISPPLGAMSTTRPSPTMSGISSIGTSRRSLSDGRGSIVSAASARRLSNAATVGSSGYVSSLPTTTSYSAGGIGGGMTSPISHHTRSGSTGSVVGVTQRTSLYAPSAGLSAMGAGGRGLSNSDLNLPNVAPRRAVSAMVQPTSTIRRSSGGYGASTTSIPTSPGVRGSSLGVSGGSPLSSPEYARVFVPPRQSTVSNGYSAASNGYSAANGGYSAASNGYSGANNYNNINTRSQNLNDHDVYSYRPDVPARQSSLGIGSPNGISHRNSVATLRNGGGSVGSVGNGVLAGAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SV48</accession>
    <name>A0A9P6SV48_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_005276</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002609">
        <property type="protein sequence ID" value="KAG0006465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SV48"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000196">
        <property type="entry name" value="MFS toxin efflux pump (AflT)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF198">
        <property type="entry name" value="AZOLE RESISTANCE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="208"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="1"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0006465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="241" mass="26334" checksum="F38A7FE50330158C" modified="2023-09-13" version="1">MFKSRTNAAVFVTCFFIGMGFFGIMFFMPLYFQIVRQESATKAGLEMLPLIVGLLIASISSGFMVSKYGQYLPFIWVGLALSTTGTGLLSLLTEDSSRGEIIGYLFINGFGLGFCMQTTMLAIQSSVERKDIAIATSNATFFRTVGSVLGVAIAGTVFNNAIKKNLGPLILKNPDIAAVISDSYLASTFDSAIEVQILHAYMLALRSAFRVCIPFMGLAFFFSLFIKRHKLSKTLEPVVLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SW62</accession>
    <name>A0A9P6SW62_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">rRNA adenine N(6)-methyltransferase</fullName>
            <ecNumber evidence="8">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">TFB1M</name>
        <name evidence="10" type="ORF">BGZ80_004265</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Mitochondrial transcription factor that confers selective promoter recognition on the core subunit of the yeast mitochondrial RNA polymerase. Interacts with DNA in a non-specific manner.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="8"/>
    <dbReference type="EMBL" id="JAAAID010002195">
        <property type="protein sequence ID" value="KAG0007755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SW62"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034246">
        <property type="term" value="F:mitochondrial transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000179">
        <property type="term" value="F:rRNA (adenine-N6,N6-)-dimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006391">
        <property type="term" value="P:transcription initiation at mitochondrial promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.100">
        <property type="entry name" value="Ribosomal RNA adenine dimethylase-like, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001737">
        <property type="entry name" value="KsgA/Erm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023165">
        <property type="entry name" value="rRNA_Ade_diMease-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020598">
        <property type="entry name" value="rRNA_Ade_methylase_Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727">
        <property type="entry name" value="DIMETHYLADENOSINE TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727:SF17">
        <property type="entry name" value="DIMETHYLADENOSINE TRANSFERASE 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00398">
        <property type="entry name" value="RrnaAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00650">
        <property type="entry name" value="rADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51689">
        <property type="entry name" value="SAM_RNA_A_N6_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="8" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="4 7 8" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 7 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ribosomal RNA adenine methylase transferase N-terminal" evidence="9">
        <location>
            <begin position="11"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="4"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="6"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0007755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="331" mass="36895" checksum="3B019721BFEB058F" modified="2023-09-13" version="1">MVPKTLPPLPLIRDLIRVYGLSANQKFSQNFILDKNVTGPGLLTRSILDAGAQRVVVVEKDNRFVPALQQLSEASDQRLEIIMGDMLHLDHADIFKAARELSVSPLISSAPISTTTTTNSPDQGNQDQYDQAVDSDILRPLDDNNATIRLLGNLPFGVASPLLIQWLKMMGLRQGIFQASNKVSMTLMFQKEVAEGIAAPPGHPQRSRLSIMAQSICNVKMAYKVSSGVFVPKPKVDAAVVHFEKREEPLMPGSLEKLEDVARYYFNKRRKTMGNNTNRMARLAPDVKPILEEWIAEGGWDMNMRTEDVSTEQFCALARKLDRAQIKIPLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SX36</accession>
    <name>A0A9P6SX36_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_002488</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001616">
        <property type="protein sequence ID" value="KAG0009341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SX36"/>
    <dbReference type="OrthoDB" id="5340910at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="163"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="5">
        <location>
            <begin position="223"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="68"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="295"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="78"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="332"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0009341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="349" mass="36034" checksum="A7C0F840B0D0BD17" modified="2023-09-13" version="1">MKTYPSKTVILAVATIVALIGSASIFTAEAAPIAEDLNVNKVSFGPGLESRDVHHLAKRADPIVIGTTTATHTEKAPTKTTTVAKTTTAETATKTTTKAAATKTTTSHAATTTAAKTSSASSNKDSTSTVGTVPSSTTSGASSTASPGTGSGENVPTGVNEKVFIGLGTVGGLIVFALGGVAFCRHRRKKNLATALLQQTAQFNNNNPYAKLPEPAATPKESLPMTPTKPLGTYNVVAIYTPALADEIEIGLGDSVTILQEFDDGWCMGVNNTRNTKGVFPRHCVEMGPYEGSQLGAPGGPHYPPSPSFKAAANKRMSSIAPASGWNDSAYPPQPNPPYPGPNQGGFYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SX72</accession>
    <name>A0A9P6SX72_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_002307</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001564">
        <property type="protein sequence ID" value="KAG0009522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SX72"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0009522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="536" mass="62456" checksum="4DE408FFBADAFF11" modified="2023-09-13" version="1">MTKPAISPFDIPLIVDCIGQFLTKKDYANCILVSKSMYEGFKYFHWQIIENKPCFISNQTVIPLSNVDKLALRQNGDLIRRLRISEDRKGSVLRFLAEQPAPCKNLLEFECQTHTNVTMPSLFSFVLDVLEYNSGLRKFTMKNFISEATVASCNRFLRILRNHRSLTTLNLIDTQYMGIGLYRSLLQNIPVTLESLLINWNLQSPPMPIEFPGEGWRDTYPRLQSFSVRMRRGLEETALIPFLRRCPSLRRLESLHNWGQQLCKVGSFLWDPQFFSQLSEISLDSLVLEESEWMPLISGMCGRIKVLTVDDVQIRVSLGDFFKAVTTHWADTIEIIRLESLRISSQEIELILSTCSKLKSFAVTNDLLTRPRGLRAWRHEDYDDNKADWVCLQLERLELMVLDCREPYGDDDQMDYFEEELTTNGVRRVYQQLGRLSKLQHLQTGWVSCDEFEMYSNFDLSLESGLEYLEGLKDLRVLDVHFERLKVGQIEIEWMVKNWPRLQELRGFCPSRDGDVVEMPAHIQWLRGHYPHITVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXG5</accession>
    <name>A0A9P6SXG5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">NUC153 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_001894</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat NOL10/ENP2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001449">
        <property type="protein sequence ID" value="KAG0009965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXG5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056551">
        <property type="entry name" value="Beta-prop_NOL10_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040382">
        <property type="entry name" value="NOL10/Enp2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056550">
        <property type="entry name" value="NOL10_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012580">
        <property type="entry name" value="NUC153"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14927">
        <property type="entry name" value="NUCLEOLAR PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14927:SF0">
        <property type="entry name" value="NUCLEOLAR PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23098">
        <property type="entry name" value="Beta-prop_NOL10_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23097">
        <property type="entry name" value="NOL10_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08159">
        <property type="entry name" value="NUC153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101908">
        <property type="entry name" value="Putative isomerase YbhE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Nucleolar protein 10-like N-terminal" evidence="9">
        <location>
            <begin position="3"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleolar protein 10-like second" evidence="8">
        <location>
            <begin position="381"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="domain" description="NUC153" evidence="7">
        <location>
            <begin position="499"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="543"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="572"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="604"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="621"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="632"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="643"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF23097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF23098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0009965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="643" mass="72048" checksum="23D8730164F46C5C" modified="2023-09-13" version="1" fragment="single">MALQVQNANNVKIYTVSGSKGSRSIPDWLARRNKKALKNDLEWRHRIELIQDFEFPEASLKIKTTRDGKYVMATGVYKPQMRVYEYSEMSMKFDRHTDAENVDFQILSDDWTKTVHLQADRSVEFQAQGGLHFRTRIPKFGRSLNYHYPSCDLLVTASSNEIYRINLEQGRFLNSLVTDVDPTGGNGVNCGEINPAHLLYGCGTDAGTVEFWDLRVRGRVGILAPSLPETVLSSSLSISSMKFRDDGLTMAVGTSTGHVLMYDLRSSVPLFVKDHQYGFPIKSLTFHEGSQGEDGRSKVVSADCKIIKIWDRENGNNFTSIEPTNDINDVCVVDDSGLIFVANEGIQMQSYYIPSLGPAPKWCSFLDNLTEELEENPVQNIYDDYKFVSRKELASLGLDHLVGSAVLKPYMHGFFIDLRLYEKAKAIANPFAYTDYREREAKEKLAKEAGSRIRATMKLPKVNKQLATKMMLDEAKARRKATAAGDESAATAAGSALKDNRFADLFSNPDFQVDESTNEFKLLNPVQSEKKKLSYRIVDEDEIEEASDASQSDGSDVDSDEDLVRVSNFKSGGRDKKKKPEQITSIRSGIKDRKRIPKMEALKQQANKSSAPTLKSQAQRSFEERVARDKSTANTISRSTAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXR9</accession>
    <name>A0A9P6SXR9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001655</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001384">
        <property type="protein sequence ID" value="KAG0010235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXR9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0010235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="278" mass="31015" checksum="788022875EC22D91" modified="2023-09-13" version="1">MTPSSVPVDFSRVLKFASESQSGEEKDSFMKLFNDFNCAQTNSNPSHGPTLTLYIVRQPVAAKHRRGFVQNKHESGLVGGGNTDEVVVVAQKFNGGDSLALLGVLPEIDGSDFDSNGDLARLAHIFGDTEDQQNPSQCNDDCYGSDDYDGDEAEEDDDNPRRSKKSRSESCHLPHSFRPKREDGELQYEYWTVAFLKGDFRSTSSIVHEPAPSNPDALVIVPRLSLSSIWTERVSQLLETKVMKSFVLSELSQGRIGIDYKKFLDSKRDNRGYARRVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYS4</accession>
    <name>A0A9P6SYS4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_011792</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SDS22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000994">
        <property type="protein sequence ID" value="KAG0012366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYS4"/>
    <dbReference type="OrthoDB" id="266138at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000055">
        <property type="entry name" value="Protein phosphatase 1 regulatory subunit 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025875">
        <property type="entry name" value="Leu-rich_rpt_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050836">
        <property type="entry name" value="SDS22/Internalin_LRR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46652">
        <property type="entry name" value="LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46652:SF3">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12799">
        <property type="entry name" value="LRR_4"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0012366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="358" mass="40978" checksum="5F1E4DFAFB6A20F5" modified="2023-09-13" version="1">MTDKRVQLDADEQNRLFQEAMNNGQRGGDQHGDSGDESDDENGAVQRGIPNGEEPQTPSADFLADFPEDTEELELTHLRIDDVPALRLERFKQLERLSFRQNLIPKIRGFEALTSLKELDLYDNRFSKIEGLENLTELTSLDLSFNGIRHIKAIEHLVKLKDLYFVSNKITVIENLGTLVNITNLELGSNRIRTIENLDNLVNLEQLWLGKNKITKLQNLSTLKNLKILSIQSNRLTSIEGLEDLENLEEIYLSHNGITKIEGLEKNTKLTTVDISNNRISKLENLGHLRHLVELWASNNLLDSFEDFEAELKDNCPDLETVYAEGNPLQTNNYTTYRLKMKIMLPQLKQIDAQMVRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYU7</accession>
    <name>A0A9P6SYU7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">rRNA 2'-O-methyltransferase fibrillarin</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Histone-glutamine methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">FIB1_2</name>
        <name evidence="14" type="ORF">BGZ80_011652</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-glutaminyl-[histone H2A] + S-adenosyl-L-methionine = N(5)-methyl-L-glutaminyl-[histone H2A] + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50904"/>
            <dbReference type="Rhea" id="RHEA-COMP:12837"/>
            <dbReference type="Rhea" id="RHEA-COMP:12839"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30011"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61891"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the methyltransferase superfamily. Fibrillarin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000965">
        <property type="protein sequence ID" value="KAG0012569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYU7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031428">
        <property type="term" value="C:box C/D methylation guide snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990259">
        <property type="term" value="F:histone H2AQ104 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008649">
        <property type="term" value="F:rRNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000494">
        <property type="term" value="P:box C/D sno(s)RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000452">
        <property type="term" value="P:snoRNA guided rRNA 2'-O-methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000056">
        <property type="entry name" value="Fibrillarin like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000001">
        <property type="entry name" value="Fibrillarin like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00351">
        <property type="entry name" value="RNA_methyltransf_FlpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000692">
        <property type="entry name" value="Fibrillarin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020813">
        <property type="entry name" value="Fibrillarin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003276">
        <property type="entry name" value="PRK04266.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10335:SF17">
        <property type="entry name" value="FIBRILLARIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10335">
        <property type="entry name" value="RRNA 2-O-METHYLTRANSFERASE FIBRILLARIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01269">
        <property type="entry name" value="Fibrillarin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00052">
        <property type="entry name" value="FIBRILLARIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01206">
        <property type="entry name" value="Fibrillarin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00566">
        <property type="entry name" value="FIBRILLARIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="42"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="13">
        <location>
            <begin position="42"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00032245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0012569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="341" mass="36204" checksum="0C2893EE09669869" modified="2023-09-13" version="1">MYAWRVTLDLQDYLYPSFSETQTNSTFNCFLFLGDRGGRGGRGGGRGGFGGDRGGRGGGRGGGRGGFGGDRGGRGGGRGGVAKRGGPGRGGARGGRGGARGGAKGGAKVTVEPHRHEGVFIAHGKEDYLLTKNLVPGESVYGEKRIAIEGADGTKVEYRVWNPFRSKVAAGILGGVDNIHIAPGKKVLYLGGASGTTVSHVADIVGPEGLVYAVEFSHRSGRDLINMAKKRTNVIPIIEDARHPHKYRMLVGMVDVIFADVAQPDQSRIVGINAHHFLKNNGHVVISIKANCIDSTVDAATVFAGEIPKLQEQRIKPQEQLTLEPFERDHALVVGKYVRSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T189</accession>
    <name>A0A9P6T189_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000431">
        <property type="protein sequence ID" value="KAG0017603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T189"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040472456" evidence="1">
        <location>
            <begin position="25"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0017603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="59" mass="6242" checksum="A7739670A8BD1739" modified="2023-09-13" version="1" fragment="single">MFISKTLSIVAITLATIASTFVEASPIPAIVKRSSSGYNDWTCKPSSSHPTPIVLVHGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1W0</accession>
    <name>A0A9P6T1W0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Gdsl lipase acylhydrolase family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_006251</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000308">
        <property type="protein sequence ID" value="KAG0019136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1W0"/>
    <dbReference type="OrthoDB" id="1600564at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01846">
        <property type="entry name" value="fatty_acyltransferase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001087">
        <property type="entry name" value="GDSL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051058">
        <property type="entry name" value="GDSL_Est/Lipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45648">
        <property type="entry name" value="GDSL LIPASE/ACYLHYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_4G14700)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45648:SF22">
        <property type="entry name" value="GDSL LIPASE_ACYLHYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_4G14700)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00657">
        <property type="entry name" value="Lipase_GDSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040391548" description="Gdsl lipase acylhydrolase family protein" evidence="2">
        <location>
            <begin position="24"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0019136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="311" mass="34353" checksum="9AFA1AA5421D11AD" modified="2023-09-13" version="1">MLPNLLSIAAIAIAVSSAPFALAKPTGCRPSRFRDLVVFGDSYSDTGNEYKLSNHTWPITGYYKGRFSNGPTWADDVAKTKNLKLQDYAFGGATCDSTLVQGYSGASSTIAVPGFIQQIENYYVPKHNPKDVADSLFVVSFQGNDFFFDPSLDPKLVVGKLHDGIKRLVSLGARNILVVENINMGIIPYFNTNATLAAAFTGMAAQEQVAYKALVKQIAQEYGPTDAKRPFRECKDKKKVNVGYLNLWELFARLYKSSELKRLGITDVINGCVSNDYKSVCKDAGKHFYWDAFHPTTKIHKEIADAVVHLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2E2</accession>
    <name>A0A9P6T2E2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Essential protein Yae1 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_005449</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LTO1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000269">
        <property type="protein sequence ID" value="KAG0019652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2E2"/>
    <dbReference type="OrthoDB" id="48036at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019191">
        <property type="entry name" value="Essential_protein_Yae1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052436">
        <property type="entry name" value="LTO1_adapter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28532">
        <property type="entry name" value="GEO13458P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28532:SF1">
        <property type="entry name" value="ORAL CANCER OVEREXPRESSED 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09811">
        <property type="entry name" value="Yae1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Essential protein Yae1 N-terminal" evidence="2">
        <location>
            <begin position="32"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0019652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="144" mass="16171" checksum="58A88FEC4BA9B9CB" modified="2023-09-13" version="1">MANADASQELPVELDLDSLIHLENMFVEYGREDGRAAGVRSGVIEGRVMGCEKGFEFSREVGYYAGCAQLWKSLAQLDPERISEKTLKKINSLMDLINSFPRQNQPGDDVIALLDRIRGKFKMVASAMQTAERYAEAPKSKMFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2F7</accession>
    <name>A0A9P6T2F7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">EB1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BGZ80_004857</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MAPRE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000243">
        <property type="protein sequence ID" value="KAG0020056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2F7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035371">
        <property type="term" value="C:microtubule plus-end"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072686">
        <property type="term" value="C:mitotic spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051010">
        <property type="term" value="F:microtubule plus-end binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030473">
        <property type="term" value="P:nuclear migration along microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035372">
        <property type="term" value="P:protein localization to microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.1430:FF:000005">
        <property type="entry name" value="Eb1, isoform E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.418.10:FF:000028">
        <property type="entry name" value="RP/EB family microtubule-associated protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004953">
        <property type="entry name" value="EB1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036133">
        <property type="entry name" value="EB1_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027328">
        <property type="entry name" value="MAPRE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10623">
        <property type="entry name" value="MICROTUBULE-ASSOCIATED PROTEIN RP/EB FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03271">
        <property type="entry name" value="EB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47576">
        <property type="entry name" value="Calponin-homology domain, CH-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140612">
        <property type="entry name" value="EB1 dimerisation domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51230">
        <property type="entry name" value="EB1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5 9" id="KW-0493">Microtubule</keyword>
    <keyword evidence="6" id="KW-0498">Mitosis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EB1 C-terminal" evidence="11">
        <location>
            <begin position="155"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="130"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="225"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="111"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="139"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="226"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0020056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="248" mass="28011" checksum="3512786A0FD1A056" modified="2023-09-13" version="1">MSESRAELVAWVNDLLELSYTKIEQMGSGDIPMSRVKFTTKHEYEYLANFKILQNCFLAHGVDRPIPIDRLMKCKMQDNLEFLQWLKKYWDGLYPGGHYDAAARRKGQGGHDNSMTSNRSANTPVRRAANNGAVGANRSVTGRSSLSAGNTSLRKASPDHSVVLNLQKELQEERNTVAALEKERDFYFGKLRDIEVLIQQDLERSPEFADSPLLKEIQGVLYSTEDGFEIPQEEEQGGGEGEYPDETF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2Z6</accession>
    <name>A0A9P6T2Z6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003065</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000179">
        <property type="protein sequence ID" value="KAG0021081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2Z6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="380"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="526"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="413"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="526"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="551"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="572"/>
            <end position="584"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0021081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="584" mass="65032" checksum="CF42CE2118911C4A" modified="2023-09-13" version="1">MHASATPPRDIVSNPEVEEYLRKEGMTEDEWKRVYDLRYCTILVPFEDVSDEEDAELDHENDEKDSSNSPEEPLHNHGISTPPKSQGQRQLPTPKSIQRHQDSPHAVLPKRELHTPTRNIGLRTPIEKKSTDAPKQPRAQIHNAKIRNNQEDDLAEEDTDALTINDPLASYLPAARTNAPKLNNVLGHSSDLTMDVGEDDDMEYFHDALDSHYDSDQAEDNGSSRAGLKRRHWELEQTHRLLQPTQPTAMKRVALSTSFLNTTSTETLGLLRPRSFSPSPSSIISQRRGSMTSDTSSVSHLSFNQNFSQRKLWTTQDWKTLEATYNQMNGNAMKEADLTQVADRFLEEQEAQTGEKSFWSREKVHMRCIALYRVRSDTRWDPVNHGSRRSRLESTPLSAGLRGASRRSAQPYPAQNLSKSKSNPTAIPSTGADRTSSSAIADFLSHRRADRSQKQKNADQGYQLKSVFKHRLASGLRTVGQLIPFWKDVEQGNTNIKGKQKVPLGVPLGTAQAVIDSFESKSLESECSGSSFSRSGSVLSNSDSNCERSRSSPSTPSPASSIAEMLARGHSVRSTSATSESSLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T315</accession>
    <name>A0A9P6T315_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">VASt domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_002440</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the YSP2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000160">
        <property type="protein sequence ID" value="KAG0021422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T315"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032541">
        <property type="term" value="C:cortical endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140268">
        <property type="term" value="C:endoplasmic reticulum-plasma membrane contact site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032934">
        <property type="term" value="F:sterol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120015">
        <property type="term" value="F:sterol transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032366">
        <property type="term" value="P:intracellular sterol transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13220">
        <property type="entry name" value="PH-GRAM_GRAMDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051482">
        <property type="entry name" value="Cholesterol_transport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004182">
        <property type="entry name" value="GRAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031968">
        <property type="entry name" value="VASt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23319">
        <property type="entry name" value="GRAM DOMAIN CONTAINING 1B, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23319:SF4">
        <property type="entry name" value="GRAM DOMAIN CONTAINING 1B, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02893">
        <property type="entry name" value="GRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16016">
        <property type="entry name" value="VASt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00568">
        <property type="entry name" value="GRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51778">
        <property type="entry name" value="VAST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="607"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="domain" description="VASt" evidence="9">
        <location>
            <begin position="358"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="210"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="531"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="645"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="696"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="729"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="214"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="273"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="295"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="318"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="541"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="661"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="696"/>
            <end position="711"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0021422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="757" mass="83167" checksum="6611324CAE0F3EE5" modified="2023-09-13" version="1">MNMESFQLNRPRTIASDENEFTNSDNIPKSFRNHQPYDQGDSVGQLDQGAEQSTDEGEDNDAASIHLTYANEKRFQDFHALFRSVPEDEKLIEDYGCALQKEILVQGRLYISENHICFNANIFGWVTNLVIAFSEITAIEKKFTAFVIPNAISIVTTTNTKGHFFASFLSREAAYDLLMAAWRKSFPCPANTSALENNIYVKANRSSASLNGDGDGDGDGDGDDDDAASFISARPASVTKKGRHRRGSSGTWTADEIDMDNSADFDSKSTHNNTHRHPKRAAVRKILKEVIGPGKRGDDPYDGRRRGSIGHGPLKTTDGASTTPQNITELEPGGQASGGGSSSNHLPTICKCSKDGRHYPTTFMAEVYPGSVENMWKLLFESDFNKTFLTNDVMKGADVQEDPWVKSADGNMSKVTRYTKWLGMPIGPKTTKATLTDVCEHKDFDDYVTDVTTTSTPDVPSGGSFTTKVRTCITRAGSNKVKVVVSGGVEFTKSSWIKGQIEKGASEGMTTHYKELDKSIRKYISEHPADFGSTAGVPATEESQTSTVQSQASKDNTTSGADMAKSSHAVAPKKTLAPAAVQSGKSGLLSTITGMLPSIEGEGLSQYALVAVLVIIMIANIHIWFQISSVTSQIEKVHVDVLNGQQPQQPQQDHVVGPKPMYKDSGKSNDESFTLEQEEAMWAWLTEREERHRQYQRATERDWAQVQKNDENNDSGESDNGDLNFSLAEERLQARINDLQEQLEALERSLELSALGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T350</accession>
    <name>A0A9P6T350_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">2,3-diketo-5-methylthio-1-phosphopentane phosphatase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_002464</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000161">
        <property type="protein sequence ID" value="KAG0021407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T350"/>
    <dbReference type="OrthoDB" id="2342176at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1470.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050849">
        <property type="entry name" value="HAD-like_hydrolase_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28181:SF2">
        <property type="entry name" value="PHOSPHORIC MONOESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28181">
        <property type="entry name" value="UPF0655 PROTEIN YCR015C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12710">
        <property type="entry name" value="HAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0021407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="269" mass="31120" checksum="D203C7196DCACC59" modified="2023-09-13" version="1">MPHIEVFSDFDGTISMEDTGCVLIDTGVGIDKRKEMDKQIMAHELTFLEAMGTWWGSVNLTFEEGLELLRPIEIDSGFIRFYEYVKSNNIPFSIVSCGLDVIIQSYMSWFLGEEEAKKLIIRANFGKIEGRQWNVTYWDDSPHSHDKSVCIRESKEQFKKEMFERQKEKEQSEETAEERAQEHIIVFCGDGISDLSAAREADVLFARNGKNLERYCRTHKIPFTPFDNFDEVREMIEGLKDGSLTMAEVNRRQKEECERAVVVDATQLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3J9</accession>
    <name>A0A9P6T3J9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Actin binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_001160</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000126">
        <property type="protein sequence ID" value="KAG0022055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3J9"/>
    <dbReference type="OrthoDB" id="5971719at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005884">
        <property type="term" value="C:actin filament"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030864">
        <property type="term" value="C:cortical actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030833">
        <property type="term" value="P:regulation of actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11281">
        <property type="entry name" value="ADF_drebrin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11819">
        <property type="entry name" value="SH3_Cortactin_like"/>
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        <property type="entry name" value="Severin"/>
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        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="ADF-H"/>
    </dbReference>
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        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10829">
        <property type="entry name" value="CORTACTIN AND DREBRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10829:SF25">
        <property type="entry name" value="DREBRIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00241">
        <property type="entry name" value="Cofilin_ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14604">
        <property type="entry name" value="SH3_9"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00102">
        <property type="entry name" value="ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55753">
        <property type="entry name" value="Actin depolymerizing proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51263">
        <property type="entry name" value="ADF_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="ADF-H" evidence="5">
        <location>
            <begin position="6"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="538"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="646"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="170"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="228"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="251"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="278"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="316"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="348"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="466"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="518"/>
            <end position="537"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0022055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="705" mass="80562" checksum="543836AC7481E516" modified="2023-09-13" version="1">MSLQVNFTTHGHDLKAAYEAILRPSDPKNGDNWVVFGYDKGSNDLKVLNQGNGGLEELQEEFVDGKIQYAFARVVDPYSKLNKFVLVAWCGDGVPESKKGLFNSHLSDVARFLSGFHLQINARCEADVTPALIMRKLDEGSGSKYSTHKENYQAERIQPLQSAYKRTEIPDIAALQRNPTKPEPAPKYNIGTKPQGFPASSTSTPSKVWPPPASSSSSSSAPSPPSNAAPERSWKSSVGSSYSAASSATSFNKVQPPSSLTSYAQSAPEPVVNKAHQIRLEREAREKEERERIKREIAASEARNRQPEPTSTAQRLAEERRLQEEKERERERERAQEQEPVRNVGVNRFREERLAREKEERERAAAEDSARSAREAFKEREQSNLREQASTREDEQRRQIEQQKREREAKEQEERRAREQEESHRRQQEEDARRRQEEEESRRRQQENEAREEENRLRQQQQEEEEHQHQYEEEQRQRQHEEERQRQREEEERQRQYEEEQEERRRQEEAAEQERHLQAQASAAAAEPVAAASHPAHSNTVSAVVLYSYEKAEENEMSLFEGEVIRNVTELDVGWWSGESEDGTRSGLFPANYVEVIESSQEHAAAHGEEPAAVAAEQDLHYQEHEEAHDHYAAEQHHEAAPEAHGSGHSALALYDYQAGEPNEISFAEGETITSIDFVTDDWWSGTNSAGAKGLFPANYVELHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T434</accession>
    <name>A0A9P6T434_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_009598</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000059">
        <property type="protein sequence ID" value="KAG0023371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T434"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052145">
        <property type="entry name" value="Mediator/Homeobox_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24330">
        <property type="entry name" value="HOMEOBOX PROTEIN BARH-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24330:SF19">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040351328" evidence="3">
        <location>
            <begin position="25"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="148"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="384"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="657"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="734"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="241"/>
        </location>
    </feature>
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            <begin position="307"/>
            <end position="320"/>
        </location>
    </feature>
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        <location>
            <begin position="325"/>
            <end position="339"/>
        </location>
    </feature>
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        <location>
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            <end position="355"/>
        </location>
    </feature>
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            <begin position="404"/>
            <end position="441"/>
        </location>
    </feature>
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        <location>
            <begin position="497"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="540"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="557"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="589"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="658"/>
            <end position="672"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0023371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="771" mass="82999" checksum="E19FE2F5D6C72109" modified="2023-09-13" version="1">MHSATLKPLLLALGAVSWIGTVSANIDFVNFAANLTVNPGDTLTLRWTPAPAENGTVADLGNFNLILRALTGQKYNIQSNISQALGTIDAQIPKTATGGKHSFYADYLSLPKGSSTNQFIINGAIVTTTAASSTPTGGSSTADTGISAGALAGIIAGAVVLLIVVALIFFCRHRRRAAVANIDSRSMDDKDQDKESLTKSAGSAGGLGDGGMVNIPINGGPAPRRPDESPRMQQRQQEDAMQRPLSPARNPFEGPGTSPRLNQNQQFQYQPPQPYPGNPAMGASSDNRESFESELESAYDPKRPSRMLTNGGSHFINSRGPTGASPLSHSASTGSTSSSRYPRNMQPQNQSQNPFGQDDQETLAVAAAAATASPLLANKQMSPARLKEIEMQPLDIQQHHLEQQQKMLQRQQQQQQQQQQQQEVQGSAQPKAPAPIPAAQQSINPTQFDDKAEVEEDTTVYNGYRDTIFGHYAPQQGDEDDEEETPVPALPTLPVIASQQPEQPSTNVVQRKKSVKFTGVPISGPIVLPNHEAAKEHQAQRQQRQQQDQPRPLSEVVTDDVEAYFNEDEDEDEDDVKMRLMRSEALSAVSPSSESRPQINTSVGSSDANVLSPVCSPEQSSPSRNIVGYVPPPPAVVDDSSDSFFGNGFYEDVLAAVEKSTTDTPEPSSSTKVTSPVAQKPVMPPVPSSPVEHVLPQQAVQQQYIPAPQPQHLQPVNQEVFGAPSPRITPAAAAKTQVLPLSPRTNTRPAELTTAHHEDDDDQEFYDNSIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T4Q6</accession>
    <name>A0A9P6T4Q6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Werner helicase interacting protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">WRNIP1</name>
        <name evidence="7" type="ORF">BGZ80_000898</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000012">
        <property type="protein sequence ID" value="KAG0024597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T4Q6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008047">
        <property type="term" value="F:enzyme activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017116">
        <property type="term" value="F:single-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006271">
        <property type="term" value="P:DNA strand elongation involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000731">
        <property type="term" value="P:DNA synthesis involved in DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.272.10:FF:000001">
        <property type="entry name" value="Putative AAA family ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000137">
        <property type="entry name" value="Replication-associated recombination protein A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.272.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3710.10">
        <property type="entry name" value="DNA polymerase III clamp loader subunits, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032423">
        <property type="entry name" value="AAA_assoc_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051314">
        <property type="entry name" value="AAA_ATPase_RarA/MGS1/WRNIP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021886">
        <property type="entry name" value="MgsA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13779:SF7">
        <property type="entry name" value="ATPASE WRNIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13779">
        <property type="entry name" value="WERNER HELICASE-INTERACTING PROTEIN 1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16193">
        <property type="entry name" value="AAA_assoc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12002">
        <property type="entry name" value="MgsA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="post-AAA+ oligomerization domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7" id="KW-0347">Helicase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="6">
        <location>
            <begin position="188"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="90"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="23"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="121"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0024597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="652" mass="72606" checksum="36D5A2CC05427E8A" modified="2023-09-13" version="1">MLPFGTPKAKKTNSATGTPQKQAPPSSSPASSLVPCPMCEKSIPEWFVNNHLDNDCMGMESVSESLSHVSKQKHEMDEFEDITELEPFQDNEVNGRGKAQGISSNPFIARSDAPQGHHPSQQQQQQPQRQQTQEQQIIQSRRDRVNASMQRSMPLAERARPTSLDDFIGQKELVGPGGILRALVLQDTVPSVILWGPCGVGKTTLARIIAHSTKSQFKELSATTHNVADVRKVFEDAKNLSLLNKQRTIVFLDEIHRFTKAQQDIFLPFVEKGTITLVGATTENPSFRINSALLSRCRVLTLEKLSLEDGMDRMIRRAARIKWRDILEMAQDQMTPREKSNFASTVGKDDQSINNWIDGIIEPGAVKWLIDLSDGDGKYPHSHHVHYHKDTDLITSLGRLGRSAINTLEIAVQGLSTSILSNDTERRNSGSSTSTMDTDAPNVLEKLLSASLTAESVKNAFQKTHLQYDRQGDEHYNLISALHKSIRGGDADAALYWLGRMLVAGEEPLYIARRLIRVASEDIGMADSSALPLAIATYQACQLIGMPECDVNLAHCVTYMAKAKKSVDVYYAYGLVKQTVSEEFAYPVPIHLRNAPTSLMKDLGYGEGYKYNPSYPEGVKVDQEYVPKGLKKRKFLGEFPVMKLGEDEERHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T4S6</accession>
    <name>A0A9P6T4S6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_001729</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000014">
        <property type="protein sequence ID" value="KAG0024537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T4S6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0024537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="75" mass="9054" checksum="7FD35998388DFB74" modified="2023-09-13" version="1">MLMYYMYNIIWATVVSPPTETSMWIEHDEFRLEINKRPWKIPLKYDIMMGDEIIEASPFKLQFTLQTLQNIPITK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MCE3</accession>
    <name>A0A9P6MCE3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Arm-like repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008820</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004915">
        <property type="protein sequence ID" value="KAF9991917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MCE3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056251">
        <property type="entry name" value="Arm_rpt_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23948">
        <property type="entry name" value="ARM_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arm-like repeat" evidence="1">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF23948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9991917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="210" mass="23835" checksum="F28020AA16272E09" modified="2023-09-13" version="1" fragment="single">LRGLDRLVQEGRFADFEKLAREAPCQQDPAFRWGVCLRLGEIAANTIWDLKVRKYAVNFLRQLYEDDANNGQQVNIKQWILCILDQLAESFKDIVEGSSQELLQEARANGDSGKRNLYYGYSPVQHHKMVTPQPMESPLLDRVQNKPDVETPLRKLRLERLKDRGGDVYISPRAKATPRATDNFDLTAKVQEFLDSDGKVFLVLGDSGAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MDP6</accession>
    <name>A0A9P6MDP6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">PPM-type phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_007930</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the PP2C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004163">
        <property type="protein sequence ID" value="KAF9994073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MDP6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004741">
        <property type="term" value="F:[pyruvate dehydrogenase (acetyl-transferring)]-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000222">
        <property type="entry name" value="PP2C_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832:SF792">
        <property type="entry name" value="GM14286P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01032">
        <property type="entry name" value="PPM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="PPM-type phosphatase" evidence="6">
        <location>
            <begin position="185"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9994073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="367" mass="41599" checksum="E503CDABF4FE6008" modified="2023-09-13" version="1" fragment="single">RVIPLDQRTPQKHGYYERLRARPDPNQHQQHHHERFRFNLWLHHIIQSKRAAIRAFVFGSVLTFGGYGAYSYFSRTKASEFEKFFSTWNFPSLQSSFANSTSGPSSDPTLRSFNPFSPSVNLGGPQYEKHLRMLDHEQVEERLAQNEKSFRVMTKEMERRNKSKQDLILGYCINQVASNNPIEDDLSRHVVRGKDGSIEKVFFGVFDGHGGWCCSQKVALELAPTVATELEGVMDPHDINAVMEAIENGYLKLDDRIVNETVKKVLEFPSRPLACSSLLPAISGSCALMAYIDVKEKDLYVACVGDSRAVLGVCEKSATNKNGHVWKAVPLSFDQTGRNRWEVRRLQEEHPGEENTVVMRGRVLGGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MDY8</accession>
    <name>A0A9P6MDY8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_007907</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004145">
        <property type="protein sequence ID" value="KAF9994140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MDY8"/>
    <dbReference type="OrthoDB" id="266334at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034975">
        <property type="term" value="P:protein folding in endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045120">
        <property type="entry name" value="Suco/Slp1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12953">
        <property type="entry name" value="MEMBRANE PROTEIN CH1 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12953:SF0">
        <property type="entry name" value="SUN DOMAIN-CONTAINING OSSIFICATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="57"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="226"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="2"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="308"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="57"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="74"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="115"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="148"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="167"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="260"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9994140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="371" mass="41018" checksum="71401DE942C55A97" modified="2023-09-13" version="1" fragment="single">QLKQEEEEEKRIAEEEKRLAELEKARQAEADVEDTEEIEDIDIEEIVESTINIRKENRTEGIELTDSIKDDLESNNNIAVTPESQPEFDQILPQADQKLPKDDAMDNTGSAPHSLEQENLHKDSVNGQIEVPSPSEHTGAGSPSLSIQDRDKAATGGEESSHRDESAPTQVASPETTLVAFEETTLTSTVHEVPGTLLPHASTSPASMHDDDDWVNEDLGMITLSSKARPTQPPKPSSSSKPPSGGVGTAHIGPSSATDSSPHPVPSTHSSQESVYKNIVNRLKVLELNSSLSYQYLEEQSNIFNEILESSEQKINQLVSHLNEATRRLETLGRKYDQLAYSYRAHIEVDGEKRRQEFVNLSTQVHMLVSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ME04</accession>
    <name>A0A9P6ME04_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_007898</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004136">
        <property type="protein sequence ID" value="KAF9994178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ME04"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9994178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="87" mass="9641" checksum="200D95C610707596" modified="2023-09-13" version="1" fragment="single">MAAQPGSEVYLALVKSTNPKQSKPDIALLSYLENEFPNVFPDSLQVGLLPDRGDAMKIETHPTANPSIRPVIHLSIAELDKLRKQLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ME14</accession>
    <name>A0A9P6ME14_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Wd repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_007888</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004122">
        <property type="protein sequence ID" value="KAF9994227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ME14"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.80">
        <property type="entry name" value="E3 ubiquitin-protein ligase SopA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879:SF9">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25173">
        <property type="entry name" value="Beta-prop_WDR3_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141571">
        <property type="entry name" value="Pentapeptide repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="241"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="283"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="325"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="367"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="27"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9994227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="427" mass="46543" checksum="D98FAE965132AD12" modified="2023-09-13" version="1" fragment="single">MYKSLLDSGDHLEYGLSLAIFGPSKLNEETEPAEPAEPAEPTPSVSQRGSTRSVFSFERPFSTEETATADVKSLLDSPLGERNLVGKRSVLQFLTERVQQEAVFKDQLHSVIEKSKTDKAARVAAANAITILVRAGVQFIGADLRNIKIPRADLSYGMFDSAQLEGADLRKVNLRNVWMRQANLSGAQMKRVQFGELPFLEKDGDMLCSAYSPDGETYAAGLSNGSITLYEASRWIVKRRLKGHSGDIDSLSFSATNNQIVSGSSDSTVRLWDVETGECIHTLEGDDQDVNSVVYSPKGDRVASGSSDSTVRLWDVETGKCIHTFQGHDQGVSSVVYSPKGDRAASGSWDSTVRLWDVGAGECVHTLQGHSNNVPSVVYSPKGDRIASGSWDFSVRLWNTETVKCVHTLKGHSQDVTSVAYSPKGDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MEP2</accession>
    <name>A0A9P6MEP2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">glutamine--fructose-6-phosphate transaminase (isomerizing)</fullName>
            <ecNumber evidence="2">2.6.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">GFA1_2</name>
        <name evidence="7" type="ORF">BGZ80_007509</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-phosphate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:13237"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58725"/>
            <dbReference type="ChEBI" id="CHEBI:61527"/>
            <dbReference type="EC" id="2.6.1.16"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.16" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010003863">
        <property type="protein sequence ID" value="KAF9995447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MEP2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004360">
        <property type="term" value="F:glutamine-fructose-6-phosphate transaminase (isomerizing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006002">
        <property type="term" value="P:fructose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006047">
        <property type="term" value="P:UDP-N-acetylglucosamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10937">
        <property type="entry name" value="GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE, ISOMERIZING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10937:SF0">
        <property type="entry name" value="GLUTAMINE--FRUCTOSE-6-PHOSPHATE TRANSAMINASE (ISOMERIZING)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="6">
        <location>
            <begin position="2"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9995447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="82" mass="9206" checksum="9D8B9BB3B303C14D" modified="2023-09-13" version="1" fragment="single">MCGIFAYLNYLTAVDRQTITDILTNGLKRLEYRGYDSAGLAIDGDSEKDVLIYKQVGKVAALQKLIEEQKSIDWGKTFTSHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MFH6</accession>
    <name>A0A9P6MFH6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">TP53RK</name>
        <name evidence="11" type="ORF">BGZ80_007310</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. BUD32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010003717">
        <property type="protein sequence ID" value="KAF9996221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MFH6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000408">
        <property type="term" value="C:EKC/KEOPS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070525">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12209:SF0">
        <property type="entry name" value="EKC_KEOPS COMPLEX SUBUNIT TP53RK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12209">
        <property type="entry name" value="NON-SPECIFIC SERINE/THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="1"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9996221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="134" mass="14911" checksum="CD934196434A12FD" modified="2023-09-13" version="1" fragment="single">MVDTEKSLIYMEHIEGTSVRDYLVTAEGQTAEVQQKVAIEIGRALGLMHSIDVIHGDLTTSNLLMRKESGSLVLIDFGLSYVSQLIEDKAVDLYVLERAFSSTHPNTEVMFAQILDSYGESCKASKQILKKLED</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MFI2</accession>
    <name>A0A9P6MFI2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Acyl-CoA-binding domain-containing protein 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ACBP5_1</name>
        <name evidence="5" type="ORF">BGZ80_007026</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003529">
        <property type="protein sequence ID" value="KAF9997340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MFI2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093:SF18">
        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="182"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="217"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9997340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="331" mass="35678" checksum="2189208ED16F82C1" modified="2023-09-13" version="1" fragment="single">TFRHDSTQANLQNLINYNAVWAPTLNSMLVFGGNIDGEGTSQNSLYAYNTAAGWSTPPVSGDIPPPRTLACLVPAYSGTKMILYGGFASSTTNTSGPPLNDIYVLDVATYTWTKGSSSSAGRAGSACAVSGDYLIVWGGYNILASSSLTMVYDIKTDSWITSYAPPPFRPSPRPPSTSNVPLIAGCASGAVVIILLVAGFIWYRKRSNMAHSEAGLGSEVPKQYPQQKQSHDYQVPSGQRPQHIYQPPVMTADPAASYYQQLVMSPDQATGYYQPMKETHHVFQPQIYQPSPVVSDQLTAYSHDITSPQASIVTAATVSPQTNIRNPQDIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MGI7</accession>
    <name>A0A9P6MGI7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_006704</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003319">
        <property type="protein sequence ID" value="KAF9998834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MGI7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003034">
        <property type="entry name" value="SAP_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50800">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="191"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="216"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="SAP" evidence="3">
        <location>
            <begin position="28"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9998834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="249" mass="27859" checksum="999429D7E14B5D6C" modified="2023-09-13" version="1">MDSNDYKKGLDDVSNSSDSDGTHQTYLWSSYSIQQMKELLRQHGQLTTGSRSTLRKRLRNCEQIPVSATTNSIAPDELPVATIKVTAAGVEAVAKSTSASSFSSFSMVDSSGRATTLPNIDMDTAEEAATSSAFDDGVDRQMLNDLVANRSRRLSQSIRSRFSRRSNSFSAHFAEFINRRKEALETERQEISVYTSPLTVLSYFFLYILYEFRMALLWIISQQYLLVVLPAIAATVYFVYQTDGAHQPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MGX3</accession>
    <name>A0A9P6MGX3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Hook C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_006703</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003318">
        <property type="protein sequence ID" value="KAF9998844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MGX3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005815">
        <property type="term" value="C:microtubule organizing center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031122">
        <property type="term" value="P:cytoplasmic microtubule organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030705">
        <property type="term" value="P:cytoskeleton-dependent intracellular transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008636">
        <property type="entry name" value="Hook_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18947:SF28">
        <property type="entry name" value="GIRDIN, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18947">
        <property type="entry name" value="HOOK PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05622">
        <property type="entry name" value="HOOK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hook C-terminal" evidence="2">
        <location>
            <begin position="33"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="5"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="281"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="366"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="489"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="559"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9998844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="559" mass="64793" checksum="1E115A42B2FDF669" modified="2023-09-13" version="1" fragment="single">MDQELAQLHSERDELERGNQHLVAELQNMNRKYDELLTEREELKQRIRDLEKASAQASQSGKSDFLMRAEIDHLRQDLQKSEERRQEQELVINNQMKAIADLSRAEAELSAKADEAVRLKDKLDEYKHAIDKLQKTENVIEKYKKKLEEGADLRRQMKVVEDQNMELLERNREIEEEYRKVLAFKSLMESYKEQILTLETKNSTLAKEKNRIEYEIRQQEQQLQQLEADRQRDGEQMQMLEEKVRELEFSGGQGVPLSNDLQDMETDDMESSLLGQRASQITELKLKISRLERELQTLKEEKQDEGGSKATVLQHLLDDANRLKSKYEQDYLEEHQSKIVIQGELDRIRAGKGDESEVAFALRSSLNTCEKDLSETRKALAEMEANLEQTKKELVIVQSDLHMVGGDKLAALGEWKLNNSKELTSLQEEHAKLLEKNKALEEESKKYLAQLNQVLTEKDGLSKAGLEQRDKMLQEAGAQLGEAKELHTREQLELRNRHLEEQLEEKTSKLQRAKEFIVQQDARIKEGNKTNQAPGGYDEAVTSLKRELAAKDEEIESLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MH07</accession>
    <name>A0A9P6MH07_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Arf3-interacting protein 1 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_006415</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003169">
        <property type="protein sequence ID" value="KAG0000144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MH07"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051666">
        <property type="term" value="P:actin cortical patch localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052809">
        <property type="entry name" value="Actin_polarity_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012860">
        <property type="entry name" value="Afi1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28245">
        <property type="entry name" value="ARF3-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28245:SF1">
        <property type="entry name" value="ARF3-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07792">
        <property type="entry name" value="Afi1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arf3-interacting protein 1 N-terminal" evidence="2">
        <location>
            <begin position="243"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="202"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0000144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="308" mass="35166" checksum="6542C3EE198FD57C" modified="2023-09-13" version="1" fragment="single">SKDITPLQATSSQISGYYDENKPNLLVPSPSVNVKYDNGDNEFMAEILSAIQAHYGEMAIRAKFQEYVARFVQLASQYEEQTFGRTTIGLNLSNTPESAKYLGTGLVFTDDVSRSREILGNSMRIEGWRATTSYKYLQEDHQAWLSSRSIKCMDVKRVISLLKMSRTLSNQEVSSLYRGFFLNITTDEQIIETGQVYIKSLNRFERNTYERLAREYALQEEEAIRQQHEFVKMSESMTSLNTASTVLAELMLPDGAHLRPADWTIFFLNLAKPAPWNGNKALADKDCENPLLYVLNLVRTNHDASIRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MHE4</accession>
    <name>A0A9P6MHE4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_006431</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003177">
        <property type="protein sequence ID" value="KAG0000062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MHE4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF4">
        <property type="entry name" value="NAD(P)-LINKED OXIDOREDUCTASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="32"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0000062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="189" mass="20771" checksum="BB1B5FC9AB9AE263" modified="2023-09-13" version="1" fragment="single">MKDTSDSTSIDKALTALDNYVLLGKSGLRVSPLTLGTMTFGEKWGFGADNETSKKIFDAYYDKGGNFFDTANVYTNGDSERFLGEYISNKRSQCVVATKYSINTSLGELQAGLTPSRNPNAGGNHRKNLVETLDGSLKRMGTGYVDVLYVHAWEYRTPISEVMRALDDVVRSGKAHYVAISDTPSWVIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MHI2</accession>
    <name>A0A9P6MHI2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">U three protein 23</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_006391</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in rRNA-processing and ribosome biogenesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the UTP23/FCF1 family. UTP23 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003154">
        <property type="protein sequence ID" value="KAG0000290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MHI2"/>
    <dbReference type="OrthoDB" id="25675at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08553">
        <property type="entry name" value="PIN_Fcf1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1010:FF:000006">
        <property type="entry name" value="rRNA-processing protein UTP23 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006984">
        <property type="entry name" value="Fcf1/UTP23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057776">
        <property type="entry name" value="UTP23_sensor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12416">
        <property type="entry name" value="RRNA-PROCESSING PROTEIN UTP23 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04900">
        <property type="entry name" value="Fcf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24779">
        <property type="entry name" value="UTP23_sensor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="UTP23 sensor motif region" evidence="9">
        <location>
            <begin position="216"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="207"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="236"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="282"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="292"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00076388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF24779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0000290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="308" mass="34134" checksum="E25A3E075F096670" modified="2023-09-13" version="1">MRLKRHKDYKRYMNMYCQTFHFRKPYQVLVDGDFIQAALDQRMDLRTMIPTVLCDASKQMVTPCTMALLKSRGDEGSGAFLVSKRFEKRRCKHQEAVDEALCISEIISTSNPHNYVVATQSKKLRVQLAQVPGVPLLYINRANMILEPPSDASLSAGKKIESDKTHASNKELNTLKAVKVTALGKVSVDPKLIKKIDQKKEIKKQKMEIKKAKIMKKRMGPKEPNPLSVKKKKKTLATPPSKATSATTTTTTNQSTNAPTIENKKRPANSNDAATEGSAPEKKKRKRRKSKSASSATAAGTTGGSESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MIQ4</accession>
    <name>A0A9P6MIQ4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DELLA protein rgl2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RGL2</name>
        <name evidence="5" type="ORF">BGZ80_006021</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002973">
        <property type="protein sequence ID" value="KAG0002142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MIQ4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.840.10">
        <property type="entry name" value="Ras guanine-nucleotide exchange factors catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008937">
        <property type="entry name" value="Ras-like_GEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023578">
        <property type="entry name" value="Ras_GEF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001895">
        <property type="entry name" value="RASGEF_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036964">
        <property type="entry name" value="RASGEF_cat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113">
        <property type="entry name" value="GUANINE NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113:SF99">
        <property type="entry name" value="RASGEF DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00617">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00147">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48366">
        <property type="entry name" value="Ras GEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50009">
        <property type="entry name" value="RASGEF_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ras-GEF" evidence="4">
        <location>
            <begin position="402"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="284"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="337"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="613"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="667"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="764"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="19"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="55"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="69"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="145"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="160"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="170"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="205"/>
            <end position="243"/>
        </location>
    </feature>
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        <location>
            <begin position="249"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="339"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="613"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="774"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="793"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0002142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="793" mass="86965" checksum="7966430AD8B3A7E6" modified="2023-09-13" version="1" fragment="single">MLTEQLQATNPDLNNTELSPSPISSRSSSFSSRTAPTTVPAVSPPSHRPTLSVPSIPPKPTRRPPPPVASSTTTSRSPVLGFSENGTMASIGGSFSNTNSNHGNNYSNNNSRATSPPKTIDHPTRPQSMPPHSIYPPGGSESPPQSKPPLPPKPARLYRKQHEVKTEEHSLDEDDSDEDDDDDDDDDDDDDDLEGHVFSPALNRRASSPSIAIPNSSRRPGTPLSVPTSPTLSPSSISSSISSADRSRSYTLPQYTSSSQGSTLITVIPDGCVDPSNLVEAERISGDNEDQLDQKTYGPSDHIPLIPVTPLRTMHRTLVEKEKTLSTKLAEVKQRLQDKTAQLNGGDSNSKREHQEDDVDIQTLQENLTKYTSMISSAMATITKVRELLYRSASVTSILEFPAYLVAYQLTLVESAIFLEIPPAALLTHSPKTPHRSITASTDFFNYLTRMVEYSVLFPPEASGRAQCLHYWVKVAVKLHELENFQTLKAVLSALGTPPIKRLKRTWSFVPRKSMHKFETLSELMSEARNYGKYREMMSSLNAGTMLISSNVVSPIQPTSKLEMMSLNGMSNSLSNLGFRTKEAARRPMVPFLGTFIMDITYLLAAVKKSNSLTPPISSQIPSTSSLREKPALPSSSPANSPQIGTQFAPEDDVRIQDLLMTLTAYQSGPKYSSQPPRPYIKSATKSHHHFRAPSLSSALHRTAKYRTPSVDRQIGANINHQSSYEEEEDDVSGNGLRPTQQLILHYLLTRPWVPERMVDELSAIREPSKNKNGSSGSSSRTSAGGSTTQSWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MIS1</accession>
    <name>A0A9P6MIS1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005762</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002832">
        <property type="protein sequence ID" value="KAG0003639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MIS1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0003639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="285" mass="30853" checksum="1371BD6DFFA6B7E5" modified="2023-09-13" version="1">MFGQQTTQQQTKLQFPTNYHLQQQQQQQQPTHPMAMPMSFHNHQNSNNAATPNNSFAGTIDPGLLQMTMNRIDMSQLQNMNSLFPQTSGTSLSNNQALLGRGNLGTINNNLANPTIKQEAASPDYLASEIDFGEPGNMLSPGSTSPLNSPLNDFEGSDDFSTPNPGAGSSSLSKPAPLNIHPGSYGESPGSLYSPGLESDFFPEGDFSLPKSTRPLDMKFGRMHPNSLPTNPFHSMSMPVQRSEWFGAGADGHSVGSYENPSGMQFAQGEMNMMDSLFEDGSDPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MLU7</accession>
    <name>A0A9P6MLU7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005003</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002496">
        <property type="protein sequence ID" value="KAG0007144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MLU7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="160"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0007144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="284" mass="31403" checksum="D798E05785AFC8C2" modified="2023-09-13" version="1">MFDEYDELFQAMEVALDTNTKLNTAFFIEIKSENGTSNSLSCLKAPNPSINNTSFLTCMYFATQSTILKSEALEPAIASAQEGSQPLPDVTTIMSFIHLASIDKGFSAQISIAELKNRTLDVAHYLASLGQNLYVNWNQQEVAVIFETTDAEEGLEIPNWLIIFVPIIAVISAILLGSTEYFLDARYTSSLYKAITLPMRLRMNSFAPMLMRSKVGPIEFEGIPVVPSGRRFEADPKNVATLQSENNSSTTTMDDKLFSDKLSFAIEMPSSPVRITFGDNTSDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMD8</accession>
    <name>A0A9P6MMD8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004551</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002307">
        <property type="protein sequence ID" value="KAG0007540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMD8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="298"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="443"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="478"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="609"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="253"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="303"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="333"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="385"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="443"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="482"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="614"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="642"/>
            <end position="653"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0007540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="695" mass="74527" checksum="BBF23C278F4FC431" modified="2023-09-13" version="1">MATLSRSPNTSHPADALLNRARRLSSNAYERSRSPIPFPEGESCRSSSSPSLQIHHQTSFHNILLTSSSRRASSASTNAPSHSILSSHPSAVSHALISASSTIFSEKQQPIVQSPTEGTCGGLSEAALCANTFLDVRRAHTLPCATTGPCLAASLSARPRALSMESIRDTQTDEISAKQTPQRESHRKHLSENGGSLVYGILAALRQNTELESPAFPFPRQADRSAESSISPTMDSDKSLTTDPMNNNTSTETSLSAAIPSSVSISDSTNVSTLETESESALPVLVNETRESCTIDNCTFSAKEPKENSIEQETKQDPSSMVPESKQIAEPHTSTTSISPPSSTKSTGALDHEKKEGKSSLLQKMGMRKNSFNESSSAKGKDTTDSSAKSHTANSAARPSFPKASKRSSKLLGKFVHKILPISMSNTNSTPIVSPQVQTAGLSPLSARASRSSSVTSQTTHENETIIPAEAAATITLPLSPPASSKGSQESLPLVSSPHDQVVSSAPIPERSSVVFVEIVEDDREDKTSSAGYFDVEYEHEIINEDENENKQKSTEADEALMSPYVIDDDCDDDFFLNSVLRKKPNLTLDVTPERPPVMFSSYPSNTTLDSVHSAPSLSGWSSASSQASTPSPTSTSFPSSQMYPSPSTNTKAPSMHIHYRSNPLPTPINSGLDGKRTRLRDAVSEWRRSTNASF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMQ2</accession>
    <name>A0A9P6MMQ2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_004033</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002101">
        <property type="protein sequence ID" value="KAG0007962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMQ2"/>
    <dbReference type="OrthoDB" id="39175at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051430">
        <property type="entry name" value="Fungal_TF_Env_Response"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31944">
        <property type="entry name" value="HEME-RESPONSIVE ZINC FINGER TRANSCRIPTION FACTOR HAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31944:SF131">
        <property type="entry name" value="HEME-RESPONSIVE ZINC FINGER TRANSCRIPTION FACTOR HAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="42"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="137"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="481"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="137"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="177"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="206"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="234"/>
            <end position="252"/>
        </location>
    </feature>
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        <location>
            <begin position="253"/>
            <end position="269"/>
        </location>
    </feature>
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        <location>
            <begin position="271"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="485"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0007962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="610" mass="66111" checksum="9663DCBCD4786721" modified="2023-09-13" version="1">MSTSTLQLLPTSANEIAKLDPATLASIPGVAYDLKRLKVYSSCLRCRAKKVKCDRKEPCSRCEKHKVECSYRELASVQLDIRQFQRHLTNPKIRKDGAGIITSTATPIITLPSGDTAVLSPSTTAAASLIAAAKATALSTNSNTSSSDSNSSSSRKKSTKSSSTSAPPSPVEDRSSALASNSSTDTESDTPTRTPSSKSIAMARAKVNKIQRRKATTTISTPKRVKQVIQVHTEEDDENDDDDDDDDDDEEVERVVLRDDGDSTMREYQFHVQSDVSMSSAGESDNDDDEKSVPIWQAQAVGKHKQTAHEQEMAEAFGLAAYLKAKEMESSKTGQTIDYDMELERALAQRMPTSFSRPDRSLSRARKYAQAGYKPVLPYSRPSYCQLSSLPSDPNSPPLVAAHCCCQIAAMQGAARGTCYFSGNSNRSSAEYEYSSVSPPPQGIEYEQGGSTRIAYSPSCQPSYVPKDEAQAVAAAAALTKARRSTPTSSSNDAYSSMMPPPPQPLRKLEITTSSASTSPMASPRIELPPIYLPKLPSHLTTPASSDLSRFQVGGGRDGNNAKPPLEIACKYNEPNVDAWDMIERPISRPASMTTKRSRSAKMEVGWILS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMX6</accession>
    <name>A0A9P6MMX6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">NGG1</name>
        <name evidence="7" type="ORF">BGZ80_004329</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NGG1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002217">
        <property type="protein sequence ID" value="KAG0007712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMX6"/>
    <dbReference type="OrthoDB" id="1232at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019340">
        <property type="entry name" value="Histone_AcTrfase_su3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13556:SF2">
        <property type="entry name" value="TRANSCRIPTIONAL ADAPTER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13556">
        <property type="entry name" value="TRANSCRIPTIONAL ADAPTER 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10198">
        <property type="entry name" value="Ada3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="68"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="115"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="169"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="434"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="552"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="81"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="116"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="169"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="188"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="444"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0007712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="623" mass="68683" checksum="D228B68DCAF47A8A" modified="2023-09-13" version="1">MDSTTSPNIDPNALSFRNYLKTSQQASGSPSIPVIPPYQELAVLQQELLHLAEKANIRLEKYTGELSRLDGGSHLNQSKDSSVSSTPTSTTSASVAAFNSTQGASHASSAGANTLANAARSSASPNSSSPSSFSNSSRAGGSSGALAQGSGGNSPAIVKLGVVTLKLKRSDAAESSKTDDEQSSSSTPNTIKIKTGTPSLSQDGFVKKKRKRDLEEDSEYSEDDRVVALPKSKRSDDYLLSKTGRSMSPQPVKLNANRHGTPKASQNRTADKGNPSSHQKKKKGENQTDKSQKPNPKSQEVQEDFSKVKVANQVPIQTFWASMDPYFRPFTEADRAVLEEEGDNVTPLLIPPLGRHYLDAWAEEDRALLPFDGHESRRSSVDLVKDTTPSRNTVYNQPFELTDENIDQDEVSCGPLTERIICSLIAEDVVDAKEMKDDDEQMEPSTPSASASTQSNARNYAELEERIKRELRYIGLLGNDEIDWDAREDDEISITLRSLQKELREVMKVNKSRKQRLLGLVSNHLAYQEYNTILDDLDKQVEQGYLKRFRMTKSKKKKTSTPKSLSENALSSMDRRRRFVQGVGPIFPAENYTIPTKSIYQDELEPKANVGTPQTYRQLNGLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MN86</accession>
    <name>A0A9P6MN86_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003581</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001957">
        <property type="protein sequence ID" value="KAG0008324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MN86"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0008324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="90" mass="10245" checksum="ED98A67FF7FA44E2" modified="2023-09-13" version="1">MRKCREILWSRYELCENANWPNCDPLEAVLAATRDIPPRRAGPAVVSHIVELPTPDRSSSTANEEPWRYGEDGSDMADWLEGWEGLTMVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNP9</accession>
    <name>A0A9P6MNP9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_003321</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001871">
        <property type="protein sequence ID" value="KAG0008547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNP9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22147">
        <property type="entry name" value="F-box_SpPof1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000715">
        <property type="entry name" value="F-box protein MET30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051075">
        <property type="entry name" value="SCF_subunit_WD-repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19872">
        <property type="entry name" value="UBIQUITIN LIGASE SPECIFICITY FACTOR/HREP PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19872:SF9">
        <property type="entry name" value="UBIQUITIN-BINDING SDF UBIQUITIN LIGASE COMPLEX SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="1 4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="F-box" evidence="6">
        <location>
            <begin position="94"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="313"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="353"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="393"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="432"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="531"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="554"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="167"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="500"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="171"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="195"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="508"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0008547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="631" mass="70415" checksum="412E630F88FEB7BD" modified="2023-09-13" version="1">MASDSPSPSNSSGLAPSLCFNADAIEDLAPVQPSTENLLPESFPTLTWSGHHSEKNNTTKSEKRLCYRHRPDLRSKRAADEIQLEELQQPLLKIDFLTILPTEISLRILSYLDATSLCHAAQVSKSWKRLADDDVIWHRMCEQHIGLKCTKCGWGLPLLEKKRVRSRRNIEQQQRQNQSQSSHEEDHSEVYTNESSPTTSYPATISSSISYPSPSPTLSPTDERSSLNWTIRRRSVSDDSESVNPSPKRVRLCSRSPSPGFEGTSSQPAPLFQSPEPPAKPVRVAKRPWKDIYSERLIVERNWRKRNFKRKEFRGHTDGVMCLQFDDSFLITGSYDNTAKVWDIETGECLRTLKGHALCVRALHFDEAKLITGSMDRTLKIWNYHTGQCIRTLQGHTDGVVSLDFDSRILASGSVDSTIKIWNFATGECTTLKGHSDLVNKVQIYKSTMLFSASDDTTVKLWDIASRMCLRTFTGHIGRVQCLQTSGDALISILTNRRQRRLTGSQQGSGRSPSYDGSSSENESRTRKPIVITGGLDNTLRVWDAETGECLNTMFGHEEGVWSLAFDKLRIVSGSLDKTIKVWDTESGDCLYTLSGPDRPVTCVGLGDTKVVGGSADGAVFVWDYGARASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MP98</accession>
    <name>A0A9P6MP98_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Stromal cell-derived factor 2-like protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">SDF2L1</name>
        <name evidence="6" type="ORF">BGZ80_002567</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001637">
        <property type="protein sequence ID" value="KAG0009269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MP98"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23279">
        <property type="entry name" value="beta-trefoil_MIR_SDF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036300">
        <property type="entry name" value="MIR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016093">
        <property type="entry name" value="MIR_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026768">
        <property type="entry name" value="YPEH2ZP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46809:SF2">
        <property type="entry name" value="GH21273P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46809">
        <property type="entry name" value="STROMAL CELL-DERIVED FACTOR 2-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02815">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14976">
        <property type="entry name" value="YPEH2ZP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00472">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82109">
        <property type="entry name" value="MIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50919">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="MIR" evidence="5">
        <location>
            <begin position="602"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="5">
        <location>
            <begin position="664"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="194"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="423"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="344"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="194"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="227"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="239"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="255"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="480"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0009269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="782" mass="86728" checksum="F5FDAE94104F7CE0" modified="2023-09-13" version="1">MPQYSQYQYQYQHHPSAGPPGVPTSGYYGRGHNNAYYRRGEGGRNGYSSYYTPQGNGSHGHSGSGNQSKTVCRMDCRYCSAVICLRGMKAMLLADTTVELYSTDHPPGSVQLIEKDYTTSNCKCKIRDVACRVCGNIIGYHITQPCQQCLKAPNNGHFWMFHTEGVVGQERLSMDLGKLAQKLITLSRQQQQQELQQRQLRGSIDSISSRTNSNNINDNHTNDEVTESATNRQTSVSGQHHHQQQQQHRPHSRLASPTPSPTRTDPNASVSEGSRTSRISLASDAGSEVPLRTASEVLATLPIARLLQPMKWEQLPHPDLDIDLDPNSMGGEPLFAEQWTEMVMRTAEAAAANMSLALDQEEETERFLERMMEEKNLELEDSDIDGVEEDSDDDNFSEVDTRDMVAARENQRETMEQLIDQVGEFDLASPPPGVEDRKDEDCNGSYMDDNRNDWRGARAFNHRRRESQPNMAPAPRQQGSPSLSSVSTTPSPVISRNRERSRRRGSATSTETIHNPSLGICPAFAQSSASIAKAAASAAAADAASAANSLLYGRRIRRDYDMMCRNIDTTAMRLTLSSLACLAMVASVVLADPAEIEIDEEFQKVTCGSSIKLTHEKTQFKLHSHQIPYGSGSGQQSITAVPGKDDTNSLWLVMAQFGSTCDRGEPVPCGSIVRLKHVNTKKFLHSHHHNSPMSGGLEVSGYEGQDDGDNWTVECVNSKEDYWMRESPIQLRHENTGMYLSSSSKHAYGNPIPGQQEVAGHRLGYSDQKWTAQEGIYFAERE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPA2</accession>
    <name>A0A9P6MPA2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST2</fullName>
            <shortName evidence="8">Oligosaccharyl transferase subunit OST2</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_002852</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the oligosaccharyltransferase (OST) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Endoplasmic reticulum membrane</location>
            <topology evidence="1 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the DAD/OST2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001725">
        <property type="protein sequence ID" value="KAG0008987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPA2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008250">
        <property type="term" value="C:oligosaccharyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003038">
        <property type="entry name" value="DAD/Ost2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10705">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT DAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10705:SF0">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT DAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02109">
        <property type="entry name" value="DAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005588">
        <property type="entry name" value="DAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0008987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="112" mass="12045" checksum="B7D2C1F4999F443A" modified="2023-09-13" version="1">MSEVQSAISTLLSSYAKDTPKSLKLIDGYMVYVLLTGIIQFVYVCIAGTFPNNAFLAGFISTVAAFVLAANLRIQTNPKNASQFPTTSPERAFADFIACNVVVHFAVANFLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQB2</accession>
    <name>A0A9P6MQB2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_002292</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001560">
        <property type="protein sequence ID" value="KAG0009536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQB2"/>
    <dbReference type="OrthoDB" id="438553at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14608">
        <property type="entry name" value="zf-CCCH_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="4">
        <location>
            <begin position="413"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="1">
        <location>
            <begin position="413"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="32"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="183"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="445"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="72"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="208"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="469"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0009536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="504" mass="55334" checksum="19B0C957EFED62EF" modified="2023-09-13" version="1">MSGNSLANNNAVRLGAAALVGGLVVYLIWSATSSSSTPRSPPTSPSSTLTTTTTTTTTTTSSSKAGKKSTSKRSESKSEEEEKRQRQSVDIDRTEVPKAIEPPTTIPSVPEDREEKGEDEDDVVVVDKSVVEDLTESFVLVAEHSHKEIETTEEVKTISVKELSTQSTASFVEEKQEIHEHLENQHVETTEVAVEATEEQVETKEQVEEPEVPVEEAEATVEEPEAPVENQPTVIPTQVEEEIKEEILEREIETPAVYNSLISQSDEFEHVEEEEKTIEQEETMERVEEAIATSDSPFSYSNVETSRTTTSSAMSLESVVMPTVIETSSARTSHHALNTKAAIFTPSWMPVATHAASFDSRSSFLAAPTQDLSYQWALNGSVPMAQSQPQLNENVQQENGRVKMKSRCRFWPNCTNKACKFTHPSLPCRDPDNCTFGDRCNFIHPKDLNRKPSRSGNKSNPSRKESRRQNQSGAIGSMASSIDSLGLSASGTTAVGNGNPWDHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MR19</accession>
    <name>A0A9P6MR19_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">DUF788-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_001252</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM208 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001282">
        <property type="protein sequence ID" value="KAG0010700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MR19"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006624">
        <property type="term" value="P:vacuolar protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008506">
        <property type="entry name" value="SND2/TMEM208"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13505">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13505:SF7">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05620">
        <property type="entry name" value="TMEM208_SND2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="161"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="165"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="183"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0010700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="198" mass="22323" checksum="E4587C635E0DE0AC" modified="2023-09-13" version="1">MANSSQKKIAHENGKTLLSLRKGFIWVNASSSSYLVSLHRHAFYIFYRIIYHWNTFGIKLALGYFLTAGLSVFLYLQINAFGRPRYNANGELVSAGEDLSQEGLIQYAFDIIYVTWFVHVFSAFWSKMWWFYLTIPAYAGWKAWHLAIKPMLTRGGMGAAGGAAAGNAAASGSADGTKSKRREKMEKRAEKGPQVRYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRI3</accession>
    <name>A0A9P6MRI3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">A1-alpha2 repression</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">AAR2</name>
        <name evidence="4" type="ORF">BGZ80_001437</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAR2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001327">
        <property type="protein sequence ID" value="KAG0010494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRI3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000244">
        <property type="term" value="P:spliceosomal tri-snRNP complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13778">
        <property type="entry name" value="Aar2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13777">
        <property type="entry name" value="Aar2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.550">
        <property type="entry name" value="Aar2, C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007946">
        <property type="entry name" value="AAR2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033648">
        <property type="entry name" value="AAR2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038514">
        <property type="entry name" value="AAR2_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033647">
        <property type="entry name" value="Aar2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038516">
        <property type="entry name" value="AAR2_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12689">
        <property type="entry name" value="A1 CISTRON SPLICING FACTOR AAR2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12689:SF4">
        <property type="entry name" value="PROTEIN AAR2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05282">
        <property type="entry name" value="AAR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20981">
        <property type="entry name" value="AAR2_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAR2 N-terminal" evidence="3">
        <location>
            <begin position="13"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="AAR2 C-terminal" evidence="2">
        <location>
            <begin position="230"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0010494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="434" mass="49511" checksum="0D5018AD78677BA1" modified="2023-09-13" version="1">MDNETLKKLFKAGAILLVLDAPHNQLEFGIDVNCWNTGPRFRGIKIIPPGAHFVYYSLHNTKSAKSSTDESVKEAGTVEVTEGGPTGGDVRIGFWHQFESGEVVVMKWNAYNEEMELEKDHEQIARYKAESIFKDDGFVNSQDDLLDEELSRASKIIDRQQKEEAEKVTKEKLKQESQLGRTTDTILEEDETEANIEMEAESEVHMEAQIETSKLRKKTEVNTRNGSVDFTTINLRSSFQKGAVGEEVTRYSLDKSWLLNHLFTTAYRSDISAFLGEYQVAFVTMLLSYHLGAFRQWKNMTILVCQSAEAIASPNYTRLFSEFIQTLNQQLTSIPSSFFMDLLFASPDQDDMTANFLEQALKTMGRNIQSNLRRGQCSDLRKPMLELQKAVFEGFEWKIPGDFKKVQKIVELDTLSDEDDDYEEEGEYAPIIVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRW6</accession>
    <name>A0A9P6MRW6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Vacuolar protein sorting-associated protein 37A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">VPS37A</name>
        <name evidence="10" type="ORF">BGZ80_000664</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VPS37 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001140">
        <property type="protein sequence ID" value="KAG0011478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRW6"/>
    <dbReference type="OrthoDB" id="10260857at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000813">
        <property type="term" value="C:ESCRT I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006612">
        <property type="term" value="P:protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043162">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.660">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037202">
        <property type="entry name" value="ESCRT_assembly_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029012">
        <property type="entry name" value="Helix_hairpin_bin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009851">
        <property type="entry name" value="Mod_r"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13678">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13678:SF2">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07200">
        <property type="entry name" value="Mod_r"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140111">
        <property type="entry name" value="Endosomal sorting complex assembly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51314">
        <property type="entry name" value="VPS37_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0967">Endosome</keyword>
    <keyword evidence="5 6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="VPS37 C-terminal" evidence="9">
        <location>
            <begin position="364"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="55"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="188"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="477"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="332"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="55"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="189"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="217"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="246"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="270"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="482"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0011478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="510" mass="54862" checksum="1F664964B842C113" modified="2023-09-13" version="1">MDRIIGSANWGRKTANEHDSIPRRKQIESLFMELPQLRAMPNDDSRFQLTLQLASSADPHTSSSTPHLTRTTSLPATNTAHSSGSPSGAGGADNSTATLTIYLPPGFPEEEPKITIQPTVRHLWVDGTVTPCAVTGHERLMPGGWSTHANLGRIVKEIVTNIQRTGVLVGGEHSDTYGSNGATLNSFKNNNGGSASNNNAAYDEYSRKPPPPIPGNRSKSLGQFNNHSPTPTFSNANGTHNQATTGGSTSFNNFMSSSSSAESQSGQNTQMRPNTSGIYSTTASPEARIVMELSAEQIEEYLENPIAFEHFFDQLEVVVNSRTLKREWWHGNDNVARRNLQLEAEMLELQKSTSEGYQVAMQLRKTLEEKLQQQQDALWRFKPETLQSKLRSAAAESDELSESIAQSFLEGKLDQEGFIQQYRDTRKVYHLREMKNERLGPILRNHPASICGGTVAGPGQDVAGSILNIGTGTGKGSLSSGLGSGGPIGGSGGGGSGSGSGSNGDPWVVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSR7</accession>
    <name>A0A9P6MSR7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_000688</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001149">
        <property type="protein sequence ID" value="KAG0011437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSR7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0011437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="356" mass="42400" checksum="604B9DB0403C5650" modified="2023-09-13" version="1">MTYPGRHYSGATRYVAIMKVLARRFPYLDSIHIEQCSGYMTESDVIRIIRSFQLKSWSSDCWKYIDADYTTTTIITNSSSSEIKNTQIRELLASSSSTLEELILSNMTHLHGQDLIAILSQCPNLRKLSITDGFEYNLQTKTGVSVEELVDDFAPAWVCSNLEYLHISIVDVARTTKYIEPFEIDSDKENEEEQRQRQHDIEMAQRLLQLFRKLETLKNLRNVRLHWRFPLMETTRDYIRKWRKNTMEYDLPLSNGMKQILMQTLGKEHMLWMNLRWEVGAPWHRTREELKVNEIEDESDNTDYRCCCCRDDGFYELDDMYDPRNFIEEAYDLHKSRNRHHSRSDRKFLRFQKKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSW1</accession>
    <name>A0A9P6MSW1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Adhesin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_000090</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001010">
        <property type="protein sequence ID" value="KAG0012269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSW1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0012269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="382" mass="43207" checksum="3ECAA5E4643A2FFE" modified="2023-09-13" version="1">MNIPSTSIPISRPDEDPPAYPGEPLPRQNDRPNSGNDGARELRETQPLLGRERRFRPASRTNRLHMPSIKWNRTTVAILVFFVLAIIIWVASLCEDCWYTCSIPEDAQILTFNQVIDPNVFRELSLRLDKGITGDVVVSTSRDPAQRDILIKASMRASTPTMLQFISHELHLTNGSYRRAESTIFMNMTESELNQALKRNCTRVNIDIIFPRYLTEYGIIEINSLYRGNVKVNYDREFLSDQLFIRSTSGNVALDYVIVRDELNVEARSGSIYAMAAVKRAVRMTASDTVQLISTSTSSSLDVTAVSLRGRAIVTSQRRFYGHFLIWSSQSRPELIGPSDYLVVTTSDNHTIEGFYTSNGWEPPRLPRLQVKGSSARLELRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSZ8</accession>
    <name>A0A9P6MSZ8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">holo-[acyl-carrier-protein] synthase</fullName>
            <ecNumber evidence="1">2.7.8.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_011800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.7" evidence="1"/>
    <dbReference type="EMBL" id="JAAAID010000996">
        <property type="protein sequence ID" value="KAG0012354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSZ8"/>
    <dbReference type="OrthoDB" id="26719at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008897">
        <property type="term" value="F:holo-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019878">
        <property type="term" value="P:lysine biosynthetic process via aminoadipic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.20">
        <property type="entry name" value="4'-phosphopantetheinyl transferase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037143">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055066">
        <property type="entry name" value="AASDHPPT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050559">
        <property type="entry name" value="P-Pant_transferase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12215:SF10">
        <property type="entry name" value="L-AMINOADIPATE-SEMIALDEHYDE DEHYDROGENASE-PHOSPHOPANTETHEINYL TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12215">
        <property type="entry name" value="PHOSPHOPANTETHEINE TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22624">
        <property type="entry name" value="AASDHPPT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56214">
        <property type="entry name" value="4'-phosphopantetheinyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="4'-phosphopantetheinyl transferase N-terminal" evidence="3">
        <location>
            <begin position="41"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF22624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0012354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="303" mass="34359" checksum="6F9031F7DEB8E528" modified="2023-09-13" version="1">MPIVRWAFDVRQSLSLENVEPLVTLLIDGDNDKRIVPVLNLLNYLPESESDSLLQIRLEDGMRRALVARLMLFAFFTAYHKCRWEDLTFDKSKSTKPVLLSPEHLVNVSFNISHHGDWVVLVGETETCAGSPVLLGVDVVNFQGPHLREPSETLSSYIQDQQFTPKEMSFMAEAPEESSPSSNESQLERTRRPWCLNGSIVKALDAPSDFVLKSIEFTIQDEEETEKPIHSTVIEVRESKPGLPEEGWSFEEALLDENHRYAIAAQSVAEKTIFDGSEIRRLDWKELLKDAVPYPDRTSPTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTA7</accession>
    <name>A0A9P6MTA7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">TLC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_000496</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001101">
        <property type="protein sequence ID" value="KAG0011704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTA7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055088">
        <property type="term" value="P:lipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006634">
        <property type="entry name" value="TLC-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050846">
        <property type="entry name" value="TLCD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13439">
        <property type="entry name" value="CT120 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13439:SF0">
        <property type="entry name" value="TOPOISOMERASE I DAMAGE AFFECTED PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03798">
        <property type="entry name" value="TRAM_LAG1_CLN8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50922">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="50"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="85"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="127"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="160"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="TLC" evidence="7">
        <location>
            <begin position="1"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0011704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="219" mass="25108" checksum="31F7441F9A3E6951" modified="2023-09-13" version="1">MTIVGTYLLITVDWSKNDISTFKSPITPFLVGLELGYLTQDTAFEFYQRIMYGIGSNLILFHHVAVVMGSVYYLHSLTLTNPGPYFIGMLSLMNLSTPLLHLRWVLQSRGQTFFNSRFKRTIDTSLLISYFWCRVFGNWWMGVAIGTKLGVAWYQVPWHIGRIFTVTTTVMFLMNLVWWLILAKQWLKSVQRFYFAKQPTATTTTTTGAGDAATAKKLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTF4</accession>
    <name>A0A9P6MTF4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cell survival pathways protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">SVF1</name>
        <name evidence="7" type="ORF">BGZ80_000374</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SVF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001076">
        <property type="protein sequence ID" value="KAG0011856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTF4"/>
    <dbReference type="OrthoDB" id="2590239at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051385">
        <property type="entry name" value="Ceramide-binding_SVF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033394">
        <property type="entry name" value="Svf1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013931">
        <property type="entry name" value="Svf1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47107:SF1">
        <property type="entry name" value="CERAMIDE-BINDING PROTEIN SVF1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47107">
        <property type="entry name" value="SVF1-LIKE PROTEIN YDR222W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08622">
        <property type="entry name" value="Svf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17187">
        <property type="entry name" value="Svf1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159245">
        <property type="entry name" value="AttH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040384043" evidence="4">
        <location>
            <begin position="22"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="Svf1-like N-terminal" evidence="5">
        <location>
            <begin position="73"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="Svf1-like C-terminal" evidence="6">
        <location>
            <begin position="226"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF17187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0011856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="393" mass="42989" checksum="90BC7F2951C4789A" modified="2023-09-13" version="1">MPMLALVMNLAILIISSSVSSLTGYNSTPPKNGDIPNAGEGVKSAASLCKDGNYFSELTTKDLEWAISPHASTETQTFYCINDQGYFGHIQLIHSNLGIWGTPISVQMTARFRGNGINKFFSINLTNFNLSADKLSASTNLMSITLSPDGQKFTVQVTNPPDLIVSLTFERTAKGYKIGEGKSFFGDGYVSHKFWPASKVTGMMIVDGKAHDMAGQGTFVHAVQGMRPHLVASKWSFVDFSGKNVETDRSSKLSLVQFTTPEFYGSTTVTQGSIVVDGELVAVAVDNKTEFVHTELDEETGYNPPTDVNYIWEGKTIEGAKPFKAILNVRPKGLCQKVDLLAEIPWPLRKIVATFVAKPIIYQWYDEATAVITIGGDEHKVSGNVYHEATFVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTX7</accession>
    <name>A0A9P6MTX7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Rho-GAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_011569</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000947">
        <property type="protein sequence ID" value="KAG0012697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTX7"/>
    <dbReference type="OrthoDB" id="2434707at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rho-GAP" evidence="3">
        <location>
            <begin position="14"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="288"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="666"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="858"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="524"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="296"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="687"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="858"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="873"/>
            <end position="889"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0012697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="909" mass="102130" checksum="BC61D927BFC31FAB" modified="2023-09-13" version="1">MSSRNNAATKPEVMPVMDMMPIQFSHRVIMMCIEEIKLRGLRHPHLFRNGFHGPSVEAALAMLANPRKHHLFSAKMMRIDTVAGLLTTALSRTYPPLIPPHIQEMFQNPNGRFFFELLGMLPELNRYLFVEVLDLCCALVDQQSFNQISHSKLAVFPGSCCFGLNEYKPNWDARSLMSGDLKKFSSAFYHAIYAYREERDLTEEELQEKLDTRAQILEQERIAALERQHGYKGAQAILRMEARLAKGLPAESPNALREISLYADRKEKVVADDAISILDIQLDDEDGASKVPDLDRVEEESEEEEVENVQAVIRDLRKSKSVASLGKSLYENQPQTPVTFSPVPMPTLKAAKSNISLHKGYMSPISPLSPRSPMSPGSVLSRSNTIARSVTLKLHPVSPGDIFGISQRAVEKRELEGFLAVARTVKRRRSALSKRTLQQRQMHKMRILAVQDSSSKKTPSSSLVTISTKSIRAIRRNNRLQPPQTAITPTHIPTAAALRRERAKKFRKELEVYQAKGYSFEDAIKAREADLKQQKRREKRAKKAALAKAEAEREAAVATATAAVADAIAQHGLTHGEGKELTMEETEVLEAFDYLSDEEFQEFKELAGLTDEDIEAIRAKAVALSLSKVTHDIQHMEVDTVSAPVAVAPDAIEKALRRISVVPQSESTYSDIPEPVGSFDDGEDIATEAHPENSPERTSNRPFRIPHMTSMDLMFKHASVVGDANLRLYPTRPSSPTISDYESDSMHGGLLSRAASVMKARSGGDYDDDCEDQEMDDEEYVVEVPVHRPAVPAIPYSTKPTVASKSGPYVAAPTQTQYNIRESQEIYIEAPQQQINNYQHHQNKNEFEFETIIVDYEDEEDEERQETEEEAELRELLESMSEEERHEFLRLSNQESMGVSMAADALVHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MU57</accession>
    <name>A0A9P6MU57_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">V-type proton ATPase subunit a</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">VPH1_1</name>
        <name evidence="11" type="ORF">BGZ80_010950</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the V-ATPase 116 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000820">
        <property type="protein sequence ID" value="KAG0013645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MU57"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000220">
        <property type="term" value="C:vacuolar proton-transporting V-type ATPase, V0 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051117">
        <property type="term" value="F:ATPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007035">
        <property type="term" value="P:vacuolar acidification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002490">
        <property type="entry name" value="V-ATPase_116kDa_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026028">
        <property type="entry name" value="V-type_ATPase_116kDa_su_euka"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11629:SF63">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11629">
        <property type="entry name" value="VACUOLAR PROTON ATPASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01496">
        <property type="entry name" value="V_ATPase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001293">
        <property type="entry name" value="ATP6V0A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="539"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="584"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="663"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="693"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="764"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="867"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="896"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="31"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="103"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="41"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0013645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="963" mass="109427" checksum="ADFED7D589277008" modified="2023-09-13" version="1">MKPRSFIIQRIARFFRSSGGEYLPLDSLRRTSTSSQIPVDAHATSTSSVASRSTSPGALTSRLRTTSSNSNSNPFIDASDEFINASTSSANHETRFDPFQHQQEVRNLHRSSSSSRGGARDVSSESTFFRSEEMSLIQLYIPAEVAQPTVSELGELGMIQFRDLNPDVNAFQRAFVNEIRRFDEMERQLRFFTSQIGKAGIHVRTSLPSSYLTHPPSRQELDEIEARLCEHENRLLQLNSSHDSIQRQYWELVEQRHVLREAAYFLEEASSRQDEVRRSLDEPDVRLLDDLETGPSQEANGLGLALGNVTGVIPRTKLQIFERILWRTLRGNLYMNTADIDEPVVDPSKETTVEKCVFIIFVHGQEILAKIKKIAESLGSTLYPIDSSASKRQEALQDVSRHIEEFDSVLLNTAQTRHQELLRISVNMTVWMTIVKKEKATYHAMNQFNHDSNRKYLIAEGWCPTKEIGTIQAALRAVTERSGSTVPSILHELRTHKEPPTFHKTNKFTAGFQAIVDAYGMARYREVNPGLFTIISFPFLFAVMFGDVGHGILVLLLGIYLVLNERKLANIDSEMFGMVYGGRYIILLMGAFSIFTGMMYNDMFSRALPFFQSGWKFNIPEDYDGKTVIVAEPTGYTYPFGIDYAWHGTENYLLFTNSYKMKMSVILGVIHMSFGICMVYYNAKFDRKPIEIIGGFIPQFMFMQCLFGYLVMMILYKWTINWFETDAAGQALRNSPPSLLNTMIYMFLSPGSVNEGDKLYPGQGFIQGLLVLVAFICIPWMLFMKPYYLKHEHCKARGMGYHQPSENHVRISTDSSHTGEAGGAVVAEEDGEHEEEFEFSEELIHQVIHTIDFCLGCISNTASYLRLWALSLAHAQLSEVLWTMTLGMAWGFTGRIGVFMTIVMFAMWFCLTIFILCGMEGLSAFLHALRLHWVEFNNKFYQGTGYPFEPFSFAVVLSEKESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUB0</accession>
    <name>A0A9P6MUB0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_010855</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000801">
        <property type="protein sequence ID" value="KAG0013795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUB0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040323873" evidence="2">
        <location>
            <begin position="22"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="83"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0013795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="240" mass="25750" checksum="C6074701E8F39F08" modified="2023-09-13" version="1">MKPSTFTSLFLCFCGDFDVAAILLDAPSIRSHSAQNETKAPKSPNVKKSKASSIGKLKTSTVKAPEPYSDKTTTPRPVDVPKSSVTTVSNASSTEQRRTSSTKAPEPYLEETTKSRPTDAPKFSLAVVPNATTPSAYKRIPIKTTEPTTAPLIVQKSSSTDAYTPPPPKYVSIKATESTTTPLIVQASSNTDAYSQISQKPLNYNQNQPYPGQCCATASTTGVQCRNPAENGYRGVREPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUC7</accession>
    <name>A0A9P6MUC7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Inorganic phosphate transporter pho84</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">PHO84_7</name>
        <name evidence="8" type="ORF">BGZ80_011614</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000955">
        <property type="protein sequence ID" value="KAG0012640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUC7"/>
    <dbReference type="OrthoDB" id="433512at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17364">
        <property type="entry name" value="MFS_PhT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24064">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 22 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="115"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="139"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="177"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="216"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="300"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="349"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="375"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="400"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="439"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="473"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="40"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0012640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="521" mass="57184" checksum="65DCADF9C280A08E" modified="2023-09-13" version="1">MSNIDYDRSQVGKPTPEEIKPKDGLAELEEQSWNWFTIRTLITSGTGFFTDAYDVFIINLVVPMLGYIYFKQNGNKLPSGTEGSLKGMSSFGTLVGQLVFGYLGDAVGRKRIYGLELMIIILGTLCCAMSGSNVKGSSVIQYLTFWRFVLGFGIGGDYPMSATVTSEWAAAGRRGQLMSIIFSMQGIGNLMASVVTMIVLACFKSAIESDVDNLDIVWRICVGVGCIPAVSTVYLRLTMPESPRYALDVENDVEKANQAVAQAMDSKAIESTSSAVVAKTKRNHNRDFIEYFSQWENLKVLIGTSVTWFLLDVAFYGVSLNQSYVLNAMGFVGDGTVYDNLWKTTLGNLLVSVLGFVPGYWFTVFLIERMGRRRIQFMGFGMVTILFVILSAAFHQLKNIVPLFVALFTLLQFFFNFGPNTTTFVVPGEVFPTRVRATAHGISAASGKLGAIIATFGFNSLVEVGGPVGQHAFLPQVLGIFAAMMGLGFLFTFLVPETMGMSLEEIEERGAKRANWQADSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUE7</accession>
    <name>A0A9P6MUE7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_010667</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000769">
        <property type="protein sequence ID" value="KAG0014064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUE7"/>
    <dbReference type="OrthoDB" id="550575at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="8"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="532"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="556"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="578"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="594"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="643"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="730"/>
            <end position="743"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0014064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="743" mass="82530" checksum="99AB66F55D2FADAE" modified="2023-09-13" version="1">MPNPLLIPEILHAVFNNLDAPALAVAAIVCRSWNAVATQALWVDIPRLHPNTLLYVLTRRYGHHVRKLDILLTGDPAAAQLNYVLQVTPHLKKLAIKLLDWTAQTALPIFRVIETNVAANLDSLSITINTRDDFPHRPYTITAEDAIAFFPTLSRLTKLELYIFPTDETMSIMLDSLPRLSAVLFSHPTASDPSNDQEFELEYFGDNTLRLMGQKLKDLRNLTIKHNQRITSTGLVDFSTFCKTLTRLSLDTCCQPIADGLEFLIEASPLLTDIVLSGTDAGDDALVKLAAPARAVNLQMLAVEGCPRISTVGVLAIVKSCSALKDLNFSICYNVLIDVFTDSEWKCLQLESLEFGGIHHPRIQLRNVSDFDITGMYKQLRKLQHLNYLNMSSLPIELKLFNSGRVAIESMKKLNKLALCDRKDVIEDREVIWLATRLPSLRMLRIDHDRARRKLIDDLHQVNPLLHINLVNRTSDSLDGFDESDGSDSESFEPHVLGAYAMSSDSYEDSGTDHGSHSSEYSNYTGSHCIASNGFHRSEDESDSPDDSHSSLALDSIDDSDPDDSDDSYDFHDSHDSQGSFSDRTSATYSSDISDNSQESQDSGDSSRSSQYYSDDDDGNEVSGRELVSEDGDEGEISGYMPEVEDDVPEDDDVSEGDDVSEDDEDVSEEVDVSDGVEDESEDEVDIYEDEGDVSDDELGVSDDEVDVSDDEVDVSDGEVGVSDDEVDVSKGSRGSQWQRRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUK2</accession>
    <name>A0A9P6MUK2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_011166</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000866">
        <property type="protein sequence ID" value="KAG0013301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUK2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045719">
        <property type="term" value="P:negative regulation of glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF51">
        <property type="entry name" value="PAS DOMAIN-CONTAINING SERINE_THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="271"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="98"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="378"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="384"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="300"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0013301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="602" mass="66849" checksum="C828AAC31589BDC2" modified="2023-09-13" version="1">MAAQIQQHRNIIVIPRDIYQKCTEDMPIPRTRLLRGRDAATRKRLLNAPDCNVSRQGYAQHGATIPAPTSSRPTTNDLLAAPSHASVSFPSSPSLTSSLSSFSSSSSSSSSSSTSPSFDTSPVVGSCKYGQGNNAVTIGGHITTIHLRGLSIASPKKRKLSGVHAPQNKNDEIFMTNKKLKVEKNQVRSPSPQKPAREVIVISSDDEADEEAPTSKYTAATAASATEGHHKYDLDPALRRVVDTIFPAFESHNKATLERAFATSRILRENYIVTRYLGSGASGFVLAAKREFDGREVAIKVIPHTGDHVEQKVQRELGILLRLKEHENVLSFYDHFTSSLYGDIDPDDQSNKDISYIVTEMAGFSLFDFIELHKPVQDEDASTRSKNIQELPRSATSPPSIYGSAIQEDALRSIFTQLALALHSLHSQNIVHGDVKDENALISVDRATNTYRAKLCDFGHSKYLQPGSSPCFSFYGTTILAPPEMDNNVAARQKSKEPNRRTGNQSTTWDLFYGYEADVWALGLTLYTMIHGDLPKELYETGKKLAAYKRKRASHRMFPFTLQENIDSDLKDLLKNMLAVDPTRRLTMSEVINHRWMLRKPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUK8</accession>
    <name>A0A9P6MUK8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_011478</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000927">
        <property type="protein sequence ID" value="KAG0012838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUK8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990234">
        <property type="term" value="C:transferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.80">
        <property type="entry name" value="E3 ubiquitin-protein ligase SopA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847:SF637">
        <property type="entry name" value="WD REPEAT DOMAIN 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05729">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141571">
        <property type="entry name" value="Pentapeptide repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="NACHT" evidence="5">
        <location>
            <begin position="71"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="657"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="699"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="741"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="407"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="789"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0012838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="789" mass="89804" checksum="54F9A7D312F5EA05" modified="2023-09-13" version="1" fragment="single">MLPMPPGSLLLDSVQNKPDVKAFLLQLRQERLQEYDPDVYISPRARVNRSATETFDLRSTVQEFLDRDKKVFLILGDSGAGKSTFNRALEIDLWHRYNKADRKIPLFIHLPAIKDLERDLVAARLRQANFTENQIRKLKQHHEFILICDGYDECQQTRNLYTSNRLNQLGEWRAQMVISCRTEYTSAEYKNFFQPTDRNSRGNWELFHEAVIAPFSKDQIQDYIDQYVISRKSLWKTEDYRRALEQIPNLKDLVTNPFLLKLALEVLPQLLETNSEFSKARITRIKLYDEFVAQWIERSQKRLLDMDLSPRHKEAFRILSDSSFIQLSITYLKDLATEIYNNHGGNPVVEYSEYRDNKTWKKSFFSHNNGKNLLREAIPLVRNIDQYRFVHKSVLEYGLSLAVFDPSSCTRDSNQEPRSSRRGSAGSVLSFEAPTLKEDLTTAIEQSLLDSPFGTKSFVDEPSILQFLGERTQQQPVFKEQLLAVIERSRTEKTARIAAANAITVLVRAGVQFNGADLRDVKIPRADLSYGVFDSARLDGADLRKTKLHNIWLRNANLSGAEMTGAQFGELQFLQEEDIVEQCEYWHGGKTLAVRLRNGCFYLYDTSSWEKIKEFGAFDDQSGFFMFSETSDRIAYNGDGLILRLVDVKTGNCFQTLKGHTKSSNSVAYSPCGSKVASGSGDRTARVWNVETGECIHVLEGHDDIVYSLAYSPSGKEIASASFDRTLRLWDVETGECIHVLQGHIGQVYDVVYSPNGGQIASAGADGTVRLWDIKTGTCISNLQGHIGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUY3</accession>
    <name>A0A9P6MUY3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_010378</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000715">
        <property type="protein sequence ID" value="KAG0014553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUY3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090575">
        <property type="term" value="C:RNA polymerase II transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050936">
        <property type="entry name" value="AP-1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621:SF6">
        <property type="entry name" value="AP-1-LIKE TRANSCRIPTION FACTOR YAP1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621">
        <property type="entry name" value="TRANSCRIPTION FACTOR KAPC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00170">
        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="5">
        <location>
            <begin position="353"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="225"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="263"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="461"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="369"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="263"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="291"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="463"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0014553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="483" mass="54115" checksum="CA18CFC2525BFF6F" modified="2023-09-13" version="1">MLQMQSMYSNNDNLFNMSHPILDSDVSKFMNGESIDYMQPAATSPVQESLMAPYYPQQQHQNQRQHQIQFPAPTTVPHSAPSSPPFQVKTEEPQQHNMDLFLLQNSFESTQDHHILQSQRSPQMNLQIIHQHQQHQQKQHQQHQQLRLQQQQQQFQQQQMMFETSHSTATTMSIPAASIMVSSASYAPSTIATTTPFFHPSSISHDDTHTVPTLGYQQRLNAYTPAAHPAAPKRKIEERQSSPIHSVDTAVAVSAKNLVISEESSYPSMKSSAAISSRLSTSSRLDKVKPTRSTKISKSTPSSSSASSSEMIAAVANKKTTKKASESRESSEQPENNESTPRVAGTGNVTHPRRAAQNRAAQRTFRNRRKAYIKELEQKVQEIDQTRELMESIHQENQEVWRRLQILENLVRKHELPVPDFAPLIPNTVSNMDFLGNALGGSNVNANANGGLMAMMALGGSSNEEDEDEGDMSDSFSQLQYQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVU0</accession>
    <name>A0A9P6MVU0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_009893</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000634">
        <property type="protein sequence ID" value="KAG0015378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVU0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24296">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0015378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="502" mass="56977" checksum="21D815CF115F979C" modified="2023-09-13" version="1">MDTAAGYLTRASKASPLFKTFLKSLTRKNASHFLGLYVLWIIFKYRSTAYGAKPRYDLKGPRGLPLIGNMIMMITTPRDQISQQNERLHEEYGTTFAFSVPKLGRVIQFIDPDVLEHVLKTNFWAYEKGPIVQESLSDLLGTGIFGADGDHWKWQRKMASHIFNVKAFRNYTSSVFVKEANVLVDYLDKAAREGRVVDIHQLFYLYTLDSFGEISFGQSFDCLKKPEEEVEFAAAFDRLNTVVFNRLFDGLWRINEWATGAGKQVVKDKKVINDFALNIISSRRINGYDKPQKDLLQLFMDMDGDDGRPLSDEMLCCLVLNFIMSNSDKSFVSKLSKEVDEVLQGGLPSYEACKQMKYSEACLYEGKSERVLPYMNKILRLDVGNGTKVYKGEFVSWSSWTMGRSTSIWGPDAKDYNPDRWMNGEKPSPSKFPGFHAGPRTCLGQQFATIEAVTVMGMLFQKFKFELVDPNTEPSYVPGLTLPMAKGLPIRVFHRTPTASAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWK0</accession>
    <name>A0A9P6MWK0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Methionine synthase reductase</fullName>
            <ecNumber evidence="11">1.16.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BGZ80_009381</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.16.1.8" evidence="11"/>
    <dbReference type="EMBL" id="JAAAID010000557">
        <property type="protein sequence ID" value="KAG0016175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWK0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030586">
        <property type="term" value="F:[methionine synthase] reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050667">
        <property type="term" value="P:homocysteine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.360:FF:000059">
        <property type="entry name" value="5-methyltetrahydrofolate-homocysteine methyltransferase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.990.10">
        <property type="entry name" value="NADPH-cytochrome p450 Reductase, Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003097">
        <property type="entry name" value="CysJ-like_FAD-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001094">
        <property type="entry name" value="Flavdoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023173">
        <property type="entry name" value="NADPH_Cyt_P450_Rdtase_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384:SF84">
        <property type="entry name" value="METHIONINE SYNTHASE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384">
        <property type="entry name" value="NITRIC OXIDE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00667">
        <property type="entry name" value="FAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00369">
        <property type="entry name" value="FLAVODOXIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0288">FMN</keyword>
    <keyword evidence="10" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="8" id="KW-0521">NADP</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="14">
        <location>
            <begin position="14"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="15">
        <location>
            <begin position="297"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="191"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00039088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00040659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0016175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="708" mass="79249" checksum="D97B30DE101A28A5" modified="2023-09-13" version="1">MTPETDPVPHTDHLTVLFASQTGNAESISRNIYEQAQERGFKSSHFVLNDFAKVDWDKENCLVFIVSTTGDGDPPDNSTKFWRHLRKLKGVGLTKAKYAILGLGDTNYDNFCQTAKRLDTRLQELGASPFYARGLADDATGLEETVDPWIKNLWPALAHQVICTPTIHDLPQPHLTSEEERIVKDIIEKQEHDHPHHASHAPSSEKPAEVSARNGDVDVASLAGVVGNLSVTEKGPVIPATGYSIEVDFSDMANHSNLTALPRVPNANLKIIELDQPTSGTTTTKFGTVPSFLQTPTPLLLAKVNSVQCLTPDDALKRTISVEFGFDDDVDYAPGDAFGIWAPNDESLVRSVLAALAVKESDMNKQIKLDGQGIPSHLQPIESATLLDIFRYAIDLTTAPKKANIRLYADYAADLAEKQKLMFMASKQGADQFNAFRAQGPTFLDILHTFPSVKIPLVRVIETLPPLQPRYYSITNSPLAKNGHRRWCCAFNVVTYELPHSVKRRGVCTPWLDELTNKVPYGKAVTSGFGSIRVAMFVKPNETKFNLPADTSKPVIMIGPGTGVAPFMGFLEHRTEQRRIKKRLMNIGTGPRQHLEDHFGDMWLFFGCRHREKDWLFKEQMQEFKNEGVLTELQLAVSREEDVRNSGKYVQDLIKIESKRIWDLLSKKEALIYVCGDAKEHGGFEKTAAMMELNKWAQEKRYLRDLWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWX7</accession>
    <name>A0A9P6MWX7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">polynucleotide adenylyltransferase</fullName>
            <ecNumber evidence="5">2.7.7.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BGZ80_009065</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DNA polymerase type-B-like family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.19" evidence="5"/>
    <dbReference type="EMBL" id="JAAAID010000516">
        <property type="protein sequence ID" value="KAG0016630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWX7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990817">
        <property type="term" value="F:poly(A) RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010605">
        <property type="term" value="P:negative regulation of macromolecule metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031123">
        <property type="term" value="P:RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05402">
        <property type="entry name" value="NT_PAP_TUTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054708">
        <property type="entry name" value="MTPAP-like_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002058">
        <property type="entry name" value="PAP_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12271">
        <property type="entry name" value="POLY A POLYMERASE CID PAP -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12271:SF40">
        <property type="entry name" value="POLY(A) RNA POLYMERASE GLD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22600">
        <property type="entry name" value="MTPAP-like_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03828">
        <property type="entry name" value="PAP_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81631">
        <property type="entry name" value="PAP/OAS1 substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Poly(A) RNA polymerase mitochondrial-like central palm" evidence="12">
        <location>
            <begin position="492"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="domain" description="PAP-associated" evidence="11">
        <location>
            <begin position="723"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="100"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="276"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="392"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="763"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="859"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="939"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="11"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="36"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="121"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="276"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="296"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="401"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="422"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="859"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="939"/>
            <end position="948"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF22600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0016630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="977" mass="110124" checksum="6296473C78333157" modified="2023-09-13" version="1">MANPRHDPPDSSVSQTSLIEPQTQQEHNMTPGFNGAAQQQRHLTGHDQYQGQDQHSPSLTGAAVGRFEQELGFNNVHPSHPPFPPPFMHPNMIHLMQQTHLHQQHMLHQQQQQQQQQQQQAFRHSQEPASSEIGQGQHNLAQRENPLDEQGQSSFQGAAPAVGREGSLGNLQQVEDQHRSPHGGPTSIDSPQMRQGSHHPMAQHHAPMFNMPGNPAPPVFDGEFGGPAMAQAHNHFMHMSRMTPPPGFGHFPMHPMQGPQFQTPFQQQQFFMHQQMLRQQQMQQMHQFQQAPPHPLQNQEDSEQFPQDGSPRQSSTVTDEQVQSGSAQQDQIKSIESQINQLLFKGDSAEGATQNLGTDNITGKSNRPLSGLTVQEIEEAQVKDLQNQLRRVSLSDPVSPPQTRSPTTNVDHSGGTIPNADSGVTSTQRMPSDRQPSNTLNSRFQNPSSDNTTNRYEQTAEKAPFSVKDIDFYSDRKYDPYRPSSHVFDLITRDAKILCQELDPMPEEETRKLALLQRLSDIANEVFGQAEVLPFGSSGNGLALANADMDVCVFLNSQQMAEEVSPVEFVERIGDRLEKDNEFENILQLKRARVPIVKLNHINGIACDIGYQNDLAIWNTRLLRAYCRVDTRVRDVVVVIKKWAKCRKINNPYTGSLSSYAYVLLVIHVLQRQGVLPNLQTIVSGNGKIPYWDCQGFNRYFFEDIPNLARYWQQTPEAATQTVGELLYEFFRYFASEFRYASHVVSIRSGGLLTKESKEWTKDFTQPHPQHPQPQAPADDAPQSEEQMQADTRPIVKNRYLFCIEDPFELNHNIGRPVDRYSLFTIRGEFMRAAKILSKNGDGAITRLCYEREIPAHQERNRNSSIDHGDDQSRDRRPHLSERHDTSSLGLGAAPQLGNRRCSGSGNTMAFPAGEDKPHNSDLHIQSRTKIQGQLDNNIGAVSSTAPNEQGPRQRVGRRSFYKRATIPSEPRHSNRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXC4</accession>
    <name>A0A9P6MXC4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SNRNP25 ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_009450</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000568">
        <property type="protein sequence ID" value="KAG0016073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXC4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039690">
        <property type="entry name" value="SNRNP25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040610">
        <property type="entry name" value="SNRNP25_ubiquitin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14942">
        <property type="entry name" value="U11/U12 SMALL NUCLEAR RIBONUCLEOPROTEIN 25 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14942:SF0">
        <property type="entry name" value="U11_U12 SMALL NUCLEAR RIBONUCLEOPROTEIN 25 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18036">
        <property type="entry name" value="Ubiquitin_4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SNRNP25 ubiquitin-like" evidence="1">
        <location>
            <begin position="80"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="SNRNP25 ubiquitin-like" evidence="1">
        <location>
            <begin position="198"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0016073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="246" mass="27686" checksum="677CAD5C701DF747" modified="2023-09-13" version="1" fragment="single">MNKEDADADADADILLRELLADPLLKDVADCLPFWEHAPIEGLKSDSELNSLPPLDADMISALLAETECLVQAELGGACRIKLEREGHETQNIVIRLDATVKDLKRVIQRKIDKVSRMNTQRLRWVVIENEKKINRTDVPGEGGQVKNSIDVSMTGDHATRSDVDSNEVMDSANEDVDTTEPSITSDQSDHVILPRYTNINWKYIWKSNCLKLDDAILLEDDKAQMREVGLKNGSVLRFVPHCKQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXJ1</accession>
    <name>A0A9P6MXJ1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Putative tyrosine-protein phosphatase OCA1</fullName>
            <ecNumber evidence="3">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">OCA1</name>
        <name evidence="11" type="ORF">BGZ80_009474</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Putative tyrosine-protein phosphatase required for protection against superoxide stress.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10684"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:20101"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:61978"/>
            <dbReference type="EC" id="3.1.3.48"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein-tyrosine phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="3"/>
    <dbReference type="EMBL" id="JAAAID010000571">
        <property type="protein sequence ID" value="KAG0016041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXJ1"/>
    <dbReference type="OrthoDB" id="6375174at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd14531">
        <property type="entry name" value="PFA-DSP_Oca1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.190.10:FF:000035">
        <property type="entry name" value="Tyrosine phosphatase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020428">
        <property type="entry name" value="PFA-DSPs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004861">
        <property type="entry name" value="Siw14-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31126">
        <property type="entry name" value="TYROSINE-PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31126:SF8">
        <property type="entry name" value="TYROSINE-PROTEIN PHOSPHATASE OCA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03162">
        <property type="entry name" value="Y_phosphatase2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01911">
        <property type="entry name" value="PFDSPHPHTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="10">
        <location>
            <begin position="11"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00039934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00051722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0016041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="166" mass="19421" checksum="4F7025D3A960D8D6" modified="2023-09-13" version="1">MTSQHLIPPLNFGMIEEDLYRSGQPNELNFPFLEKLGLKTVVWLAPEEPNQRFLDFIDDQDIHLYHLGVVSSMNAWDPITEEVVLEASELILTPKNYPMIVMCNLGRHRTGTIVGCLRKLQRWNLTSIFEEYRRYAGPKVRVLNEQFIELFDTDLVRVPVDHPKWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MY10</accession>
    <name>A0A9P6MY10_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ribosomal protein S14, S11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RPS14_1</name>
        <name evidence="6" type="ORF">BGZ80_008328</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000448">
        <property type="protein sequence ID" value="KAG0017382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MY10"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.80:FF:000002">
        <property type="entry name" value="40S ribosomal protein S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.80">
        <property type="entry name" value="Ribosomal protein S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01310">
        <property type="entry name" value="Ribosomal_uS11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001971">
        <property type="entry name" value="Ribosomal_uS11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018102">
        <property type="entry name" value="Ribosomal_uS11_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036967">
        <property type="entry name" value="Ribosomal_uS11_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007176">
        <property type="entry name" value="PRK09607.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11759">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S14/30S RIBOSOMAL PROTEIN S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00411">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53137">
        <property type="entry name" value="Translational machinery components"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00054">
        <property type="entry name" value="RIBOSOMAL_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="167"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="180"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0017382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="189" mass="20178" checksum="FC48B8DAC7E6F20F" modified="2023-09-13" version="1">MEMEYSDSTGSPMDGTLIYSTSSSRHSETHTHAPQLISTSKKAKSAPKVQENISLGPQVRGDEEVFGVAHIFASFNDTFVHITDLTGRETISRVTGGMKVKADRDEASPYAAMLAAQDVAAKCKEVGVTALHIKLRATGGNRSKTPGPGAQAALRALARAGMKIGRIEDVTPTPTDSTRKKGGRRGRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZM8</accession>
    <name>A0A9P6MZM8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7905 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_005217</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000259">
        <property type="protein sequence ID" value="KAG0019814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZM8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057227">
        <property type="entry name" value="DUF7905"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25482">
        <property type="entry name" value="DUF7905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7905" evidence="2">
        <location>
            <begin position="457"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="324"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0019814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="712" mass="80516" checksum="5C906144405FCBB5" modified="2023-09-13" version="1" fragment="single">MLNRIGMQYASSIKYDHVNYVFVITGNEPKMQKQALIALNDLIEDQRPALVNYPQKPFRDLEDLSSSIASRPQADTASGLLIDVDYSPSDSSYLQATPSQETKQTIEFQIDDRVRDPYEMYFADKREKVELPIMLGERFNCNAIISGDGRTITVSGNSKDVSSCVSQIKQMQDYFLRPPFRLDKVALVYGSSREEFRLQFVPRGSVGPGRGTPPSSRQAYSRLQGPVSSSTEWHEQENPNFGFGPTKESSIVDKQTRPSSWKPIASNSKTVQQNSSQIPWQSSGTPGNLKSQSSSTSQSNITRREVQPEWPAQSFETKDEDDFPSLGSVSKSASKSVSRPSVSPTPPKSHKPKTYKDEAGAILDNSRATTPQHMTSRSNSIVFGEQDLAYLENIPAQRSAVSRPREHDNIGLEQAALRDPTKDQEDAQRTIRSLPRLQASPETPIQRQVTPQAAFITGMRNYNMRRLSESIRNGLKELRGQRKEIRLVGRLGCVLYPMDNFILNQFWEYTQLESVIVKKREIRPVFSPIVTTNNANFNSLYGFLRTPKTETAHFEIECDTRINPTSRFTKTLVTVPTTIAVLDRVVTPWETFGEVIWNSVDKNMDFEILLQAREGAIRDTKSALGRTDVKPFSAFRKRLSIGMRNSHITCHEIKPLLEVRNINFRETLTYEKPGKFTFVVHKVEELQLTRTQGVDAVTGRTSGPGKKWYEFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZS1</accession>
    <name>A0A9P6MZS1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FHA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005093</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000253">
        <property type="protein sequence ID" value="KAG0019910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZS1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0019910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="209" mass="22762" checksum="2B35F0E272B15234" modified="2023-09-13" version="1">MATQVVATLCLETTGQTLELRQDATLLIGRGTFTGVTSTHISLEIISVSNEVRAVRLGSNRSLWNGKTLPKDAPVLLRTNGVLTLLESDFSIVVKILQETTSVVDNKSNKIDNVAKEPSIIPSKVTPPPSVLRPPPPPKSPRISDQPMKEIGDMKPDGSESDVPSNADVEMREDHSRQEDSDVSVESSIICRELSDLDNSVEEIHNIDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZU8</accession>
    <name>A0A9P6MZU8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BRISC and BRCA1-A complex member 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">BRCA1-A complex subunit BRE</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">BRCA1/BRCA2-containing complex subunit 45</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BGZ80_004936</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the BABAM2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000247">
        <property type="protein sequence ID" value="KAG0019991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZU8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070552">
        <property type="term" value="C:BRISC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006915">
        <property type="term" value="P:apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006302">
        <property type="term" value="P:double-strand break repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010358">
        <property type="entry name" value="BRE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15189">
        <property type="entry name" value="BRISC AND BRCA1-A COMPLEX MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15189:SF7">
        <property type="entry name" value="BRISC AND BRCA1-A COMPLEX MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0053">Apoptosis</keyword>
    <keyword evidence="14" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-0132">Cell division</keyword>
    <keyword evidence="11" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="12" id="KW-0234">DNA repair</keyword>
    <keyword evidence="9" id="KW-0498">Mitosis</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0833">Ubl conjugation pathway</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00025766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00032491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00032630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAG0019991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="352" mass="39850" checksum="B0774B7C23FE5A51" modified="2023-09-13" version="1">MSLYTTPKGSHHIRSHYLVQSLNYLADHAGMTLFSLKNLNLGSSQTVLNPDGNPIADVVEITMRSSTIGSNTVDLQFFYDPYDWSFPPDLIIDGLHTRPSLKDLGLDSSWDHDDPANLSREMDCSLIPGIDGPTKVVFAVPFYVVYTADGKKRRTKVVAKIQFMISSLVPNDVTAVQSKIETLSPFSHPELIQSIIEIGKHEPIVSYIERVTKKITDHFEKDERAKRLRKDFIETITSTFRENLLECDIVNNTFASFLFSVPKDMSRPDVLSTAIATFYLSDRFPEEYPKLTLTSAILPSDSNARTPAPEVIPISRYSPRWNAERIVTEIWEQLWEEIPQYHAKVSQLAALN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N026</accession>
    <name>A0A9P6N026_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Transmembrane protein 135 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_005522</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000272">
        <property type="protein sequence ID" value="KAG0019628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N026"/>
    <dbReference type="OrthoDB" id="291792at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026749">
        <property type="entry name" value="Tmem135"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031926">
        <property type="entry name" value="TMEM135_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12459:SF6">
        <property type="entry name" value="GB|AAD46013.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12459">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 135-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02466">
        <property type="entry name" value="Tim17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15982">
        <property type="entry name" value="TMEM135_C_rich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transmembrane protein 135 N-terminal" evidence="2">
        <location>
            <begin position="321"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="21"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF15982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0019628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="504" mass="56409" checksum="CA37F35442BFCE4F" modified="2023-09-13" version="1">MSNSSVTSSLTAPDLGDGPLMTKSSPTSSNNTPKMPSSDRSRKPHKDDDRANWINGKRPKGYRTPEGREAAEKSKHYKSGTTIPHLVYPCDTYEGVLRHAVLGAIRSAGVSYGAKALVNLCLGMLKVMKGKVSFAKVLKDSFAGQDAIRFGSFFGTFSFLWKLVNNGLKLYRGTDDRVNGAIAGAIAGLSILIENHERRKTFAQQMFIRSMQGVYHAGKHRGQFSFRHGDALLFAFASAQVMYAYTMHPDTIPKEFFGFMVKTARVPAEALAINRNMVRGFPLDLKQVRAMIDRHRPTKLAIETVSNMSENASVLPCAALHPWIDSCKKNNVERFVQVTKEIFPVYATLNFVPLLVLRMKRLAKDPINVVSKTTFNTLRSSVFLAIFVAGYQTQICTHRNLLLAGLPLGNSKYLYWFIGLVCAGVSIMVEQESRRAELAMYVLPKAAESLYKILYNKKLVKGVKHWDVMMFSFAMSIIMSFYQKEQQVLSPFVTRLIYHVLGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N088</accession>
    <name>A0A9P6N088_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Isobutyryl-CoA dehydrogenase, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ACAD8_2</name>
        <name evidence="2" type="ORF">BGZ80_006367</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000314">
        <property type="protein sequence ID" value="KAG0019060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N088"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052547">
        <property type="entry name" value="Mito_Isobutyryl-CoADH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43831">
        <property type="entry name" value="ISOBUTYRYL-COA DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43831:SF1">
        <property type="entry name" value="ISOBUTYRYL-COA DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase N-terminal" evidence="1">
        <location>
            <begin position="42"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0019060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="127" mass="13707" checksum="0B14EB760586F1A5" modified="2023-09-13" version="1">MASLLRSSARLASTRLRPSVAALSTQTRFVSTSPIDPSIGLTDEQKELQSLARAFADKEFAPNMQKWDEEQHFPADVLRKGAELGFGGLFVREDVGGSALGRLDTSVIIEALATGDVSTTAYITLHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N090</accession>
    <name>A0A9P6N090_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_004136</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000214">
        <property type="protein sequence ID" value="KAG0020478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N090"/>
    <dbReference type="OrthoDB" id="73348at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1050.10">
        <property type="entry name" value="At2g23090-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045230">
        <property type="entry name" value="MBS1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026939">
        <property type="entry name" value="ZNF706/At2g23090_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21213">
        <property type="entry name" value="GEO09665P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21213:SF0">
        <property type="entry name" value="ZINC FINGER PROTEIN 706"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118359">
        <property type="entry name" value="Expressed protein At2g23090/F21P24.15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0020478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="73" mass="8145" checksum="BF71EFBA6C828BC0" modified="2023-09-13" version="1">MTRGLQKLQARANAEKRAAANAPPKSQLKAMSEGNKFKCPKCLIMIANYKLIVQHMEAKHPKEPIPPESSFKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0J9</accession>
    <name>A0A9P6N0J9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Probable proline--tRNA ligase, mitochondrial</fullName>
            <ecNumber evidence="4">6.1.1.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Prolyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BGZ80_003618</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>tRNA(Pro) + L-proline + ATP = L-prolyl-tRNA(Pro) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:14305"/>
            <dbReference type="Rhea" id="RHEA-COMP:9700"/>
            <dbReference type="Rhea" id="RHEA-COMP:9702"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78532"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.15"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.15" evidence="4"/>
    <dbReference type="EMBL" id="JAAAID010000197">
        <property type="protein sequence ID" value="KAG0020778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0J9"/>
    <dbReference type="OrthoDB" id="10267474at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004827">
        <property type="term" value="F:proline-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006433">
        <property type="term" value="P:prolyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00861">
        <property type="entry name" value="ProRS_anticodon_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00779">
        <property type="entry name" value="ProRS_core_prok"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000042">
        <property type="entry name" value="probable proline--tRNA ligase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.800:FF:000032">
        <property type="entry name" value="Proline--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="entry name" value="Anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002316">
        <property type="entry name" value="Pro-tRNA-ligase_IIa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004500">
        <property type="entry name" value="Pro-tRNA-synth_IIa_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050062">
        <property type="entry name" value="Pro-tRNA_synthetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044140">
        <property type="entry name" value="ProRS_anticodon_short"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033730">
        <property type="entry name" value="ProRS_core_prok"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00409">
        <property type="entry name" value="proS_fam_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42753">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOME PROTEIN L39/PROLYL-TRNA LIGASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42753:SF2">
        <property type="entry name" value="PROLINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01046">
        <property type="entry name" value="TRNASYNTHPRO"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="14">
        <location>
            <begin position="15"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00071545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0020778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="567" mass="63432" checksum="9238B620BF1E165B" modified="2023-09-13" version="1">MVPSQQLLLRAGMMRQSSSGIYSILPYGQRILDKIEGIIDEELENIGCQKLSLPNLLTSENWKKTGRWESTGQEMFKVKDRRGSDFLLAPTHEEEVTSLIANEVQSYRQLPIRVYQVGRKFRDELRARSGLLRGKEFLMKDLYTFDVSEEEALKTYDEVVLAYRRIMKRLGVPYAVAEADTGNIGGTHSHEFHILSRVGEDSLLSCSSCGYTSNEERAVGVIPTDISKAATKFRNSQPVPKWVESLDVAPRSAVRINPKLQFGIMKTPPTDETKPEVCTLVAVATSGDRDVNEVKVSKAIGKMEFVESMDEIKPLLGEGKVDKLMLCVDQSLYPGQEPTRSKQVEINGTAIPEELSSIMRSKDSTKSLEVVYGDYHNCKPGDSCPHCFKIRGTNEPMEITRAIEIGHTFMLGTKYSRPLDAVFSPADGGAAEPIQMGCYGLGITRLLASIIEASHDKKGIIWPESVAPFRVVIVTSEDEECIKVAENVYDVVQDGLNAKSEVTIDDRVDTTLGFKMKDAELIGYPWMVIIGKGFLRTGKVEVQSRKTGEKWSLEWPEIHAFFKERRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0U0</accession>
    <name>A0A9P6N0U0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004892</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000245">
        <property type="protein sequence ID" value="KAG0020020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0U0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="5"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0020020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="144" mass="16544" checksum="AC30E5970EA11AEA" modified="2023-09-13" version="1">MEPIREIRFEDSPPAAVEAVVRYIYLGQQPILEPLCGYTVKDLMSLASYLEIERLQDHCVELVLGMSTSCDSEGETAVQILFGWGYRFPKIRQGLIQALVRDHGYGFADGKLMGLERFRDHQEYNAVVYELAAEQFNWIERDHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N166</accession>
    <name>A0A9P6N166_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fatty acid desaturase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_004745</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000239">
        <property type="protein sequence ID" value="KAG0020109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N166"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid desaturase" evidence="2">
        <location>
            <begin position="90"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0020109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="337" mass="38209" checksum="07CB02FC708128A6" modified="2023-09-13" version="1">MTDRTRNAYPFEFQASADDLKGVTLLSSASAAKEVGPTKVKRLALISSEDLKTPTIAIPTIAVAAGSLAVWGSILYYGAHKRKVSSILTFPIMTAACFAVFTPIHDGTHYSIAKGPYKKVINNLVGNLSGIPLNLPFGVYRQLHLLHHRYTNTEKDPDIWDSQGNMVLRAVKWFFPDYFWIKAVLSGEVKNAKIIQAALYYLGMIFMMKKMNDKGMAFVKYWLIPQRAAYWLLMWLFAYVPHRPDGDHQFNANDNIYKMTSVTGGILRSDGFNLAIPLLNQHLHNIHHLYPQLPFTHYGRIWAKHKDALIAGGTEIHPVYSAKQGWRWDERMDGTRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N180</accession>
    <name>A0A9P6N180_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_002973</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000176">
        <property type="protein sequence ID" value="KAG0021149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N180"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="158"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="284"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="375"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="85"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="158"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="379"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="400"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0021149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="419" mass="47465" checksum="2C9376B1EE363CC5" modified="2023-09-13" version="1">MTSPSSWSVALRHTSSQAVRQYRPLSVQFQSVRWASIVPYSVNEHSFYSPPPPPMTLEQIQQHVQRKQQLLLEEQVQLEQRQRMRQQQELQIQLAKHRNAILEQQQQQQQEMQNELAEYRKSILKQKQEQEQQQQKQQQQQQQELAQVRHDQQVHVEGGEVEKAEVGHEHETRAQETSSSSTPLPEADASRHQFIPTWRRTMFGYRGPEQVMMGVNTTTTAGDSTAAALLEMEQESMLKNASRRRSISTMITAENRVRLTLLDYTPKQIDAMTPIQADAILSSKEQQEGNQRNQKQEQQEQSTLKSEAAAATTAATSRKLLSVKELNDNKGEYHSVHTMTPFVSAAVGSVNMDVQVNGSEQQHQQERFALRVVSDVMAPTSTPSSRVLASSQRNHEGHVTGSSPTRRPTGNSSSSPSTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1D7</accession>
    <name>A0A9P6N1D7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Serine aminopeptidase S33 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004585</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000232">
        <property type="protein sequence ID" value="KAG0020224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1D7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051044">
        <property type="entry name" value="MAG_DAG_Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11614">
        <property type="entry name" value="PHOSPHOLIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine aminopeptidase S33" evidence="1">
        <location>
            <begin position="31"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0020224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="254" mass="27679" checksum="A55E81A70E5B890F" modified="2023-09-13" version="1">MANQATAFEDKWVKAEDGHDIFTRTWFAVGDPIASVVFVHGFGEHIARYDHVFVEFNKAGFQVSAFDQRGAGETGKRSNSFGDSGGYAKAIPDITEALKRGKIEGLPLFLMGHSMGGGLVLNYDSFGPLRTELSGLIASAPFVLAAPPSRPYNLTATFVATLARIVPWLKIPVRVQAKFISRDPEQVALYISDPLIKGISTTRGLTDMLTNGHALLTSRYKDITPNVPILICHGTADSLTDQHASKEFADKIQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1V3</accession>
    <name>A0A9P6N1V3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Suppressor of anucleate metulae protein B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_001200</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000127">
        <property type="protein sequence ID" value="KAG0022033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1V3"/>
    <dbReference type="OrthoDB" id="1028014at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050869">
        <property type="entry name" value="H3K4_H4K5_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12197">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12197:SF292">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SET" evidence="5">
        <location>
            <begin position="45"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="92"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0022033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="521" mass="59520" checksum="D1632B4C3D27A93B" modified="2023-09-13" version="1">MMLDPTQLQQQHLYYTNSAQETGCQAALASTVIARVVIDNTEPGPKISIDRLQTPDRGRIMVAASFIPEGALIGAIPPQAITCDTAHRTKRCGKCLGPTSCNNENGNRGGPGTIACEGCCEIWYCDERCRVQDWDAVHKYECKFLKRLYNGNGQEEEGSQRQSNDDDERYIEKFREMGDYERDYCRLMIRILIHRFKEHLLPQFEDSSRPREQEPDDGEPLPFSCVLDLVENRSGFSKELIEGNFLNVARIMDAFQTVLEQNSCEMQKPNRSQLDGSLKGVGEVEVGGGIPRLSLDELVGLVLREECNSFGLYEYGPTIEAAPTGTSSTSNSRIGYGLGLYIRNFLHSFNHSCTPNLYHVASKDRQLVYAARDISQGEELNIKYMEFTPEYRIPNAEQRRQEKERSLVKELDRKIAFEKRRAFLKEIFHFDCACQRCRWELSMNWGSSQPETSREEEEEEKFLREGLVCERDGCYGFYAPPVVLELMRRNTTSYVEKQQQLQGEEAEVGQWECVACGRQRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1V9</accession>
    <name>A0A9P6N1V9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Glycerol transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">GUP1_1</name>
        <name evidence="8" type="ORF">BGZ80_003183</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the membrane-bound acyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000183">
        <property type="protein sequence ID" value="KAG0021021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1V9"/>
    <dbReference type="OrthoDB" id="420606at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008374">
        <property type="term" value="F:O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051085">
        <property type="entry name" value="MB_O-acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004299">
        <property type="entry name" value="MBOAT_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13285">
        <property type="entry name" value="ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13285:SF18">
        <property type="entry name" value="PROTEIN-CYSTEINE N-PALMITOYLTRANSFERASE RASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03062">
        <property type="entry name" value="MBOAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="127"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="165"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="202"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="305"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="344"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="384"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="483"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="515"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="556"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="36"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0021021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="590" mass="69052" checksum="72B3C7977164A0C9" modified="2023-09-13" version="1">MADNREHQQNSLLHVNQHADAEQRATGARAEKQTVVAESSNSQASTDSQKKRTQDRSTNPSLWNTKEFYFYYLVFVTCVPYMFKTAHDASSESNPNYDKFKDLLSDGFFGYKVDNSDEQYANFRNNLPVLAAVVCVYLPLSHLFRRFFVPVTPLKSPLQRLYRTYFFLAFSFAYLFYMYGSSILKILTIVSINYTIAKLGGSARWMPAATWIFNICILFLNESHQGYKFANLHESLAWLDVYTGVNSRWDVNFNFSMLRLVSFNLDYYWCLRQNHENTPKEDRVKTSMTDKERVSTPNFVEDYNFIYYLAYTLYAPLYVAGPITTFNDFISQLRYPKDIPTKTLVMWVARLINALLTMEFTMHYMHMVAISKRQAWDNDPTLQICMIGLFNLILIWLKLMIIWRFFRLWALLDGIEAPENMIRCVVNNYSALGFWRSWHKSYNLWILRYIYIPLGGTRYAIYNIWVVFTFVAVWHDIQLKLLAWGWLISLFILPEIIASKVFSKKKWGSWPYYRHLCAAGAVGNILLMMIANLVGFCIGVDGVKLMLYDLFSTVQGWTTMICCFAAIFVCAQLQFEVREDEKRRGIFLNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1X4</accession>
    <name>A0A9P6N1X4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_000959</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000121">
        <property type="protein sequence ID" value="KAG0022146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1X4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="23"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="80"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0022146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="100" mass="10480" checksum="6828C1FE100F42BD" modified="2023-09-13" version="1" fragment="single">MSGFPKSSGLVTPPLTSPFPIQNSKTPPTTNNNSWKTVGSPPRPLLSPPSDRTRGSATEDTNVNNIDHTQGQEERESLTVSSSASSVGAVTRDGPFVTTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2M5</accession>
    <name>A0A9P6N2M5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Coilin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_011580</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000095">
        <property type="protein sequence ID" value="KAG0022635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N2M5"/>
    <dbReference type="OrthoDB" id="74813at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015030">
        <property type="term" value="C:Cajal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030619">
        <property type="term" value="F:U1 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030620">
        <property type="term" value="F:U2 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000387">
        <property type="term" value="P:spliceosomal snRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024822">
        <property type="entry name" value="Coilin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031722">
        <property type="entry name" value="Coilin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056398">
        <property type="entry name" value="Tudor_Coilin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15197:SF0">
        <property type="entry name" value="COILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15197">
        <property type="entry name" value="COILIN P80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15862">
        <property type="entry name" value="Coilin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23086">
        <property type="entry name" value="Tudor_Coilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Coilin N-terminal" evidence="2">
        <location>
            <begin position="1"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="Coilin tudor" evidence="3">
        <location>
            <begin position="443"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="142"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="233"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="324"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="345"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="384"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="436"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF15862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0022635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="551" mass="59555" checksum="C29FC2FB505C1DAF" modified="2023-09-13" version="1">MRVKLVFEDPLPPYRCWYEIPSSCSTIRDLQRSIRKGFELNQFCKTTRLDLDGFFLLPSSTVAGSVRDGDLLQVMIRKKDDNLPPRSLPAAGGKKRSRESAESPQEASKNSKRMKTNPPKQAPALNGQSRASTKPGAGHQGNKPNNTNAQKNKNNPTKPQVKKSSQDLNANKRKQKQQNAGPSQNKTRPKSATTITPPQSGIAKSTTSKQVNSSTRKGKVVPPKKSNPTKTPSTSSSSTDSSESSSSSSDSSSSDDSSTSDSDSDNDDSSDSSNSVDSSDSDSEANPKSSAIPAAKVPFGCGSSGTKARNMRRKRSALAKAQLMETTSAQTQEQDQEKGTRAVESQSSPPIISTISTKKISPQSAPNVFMTTVELKDSELMSKASKSTPSKRVTRSSQKAAASNQPKDTTIGPNPSPTIARKEAAPGIEANEDQVEDKPTPPRNYEELPKLEGHPKVGDLIAYKTLEMGPSYTPIISDFKEATITSFSETDMVAEAQLSHKFRVQFEVDSDGNTILGKFDIYDETEIDLAKRGIVSLDMLSLADCRIISRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2S0</accession>
    <name>A0A9P6N2S0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">protein S-acyltransferase</fullName>
            <ecNumber evidence="1">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_010456</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="1"/>
    <dbReference type="EMBL" id="JAAAID010000073">
        <property type="protein sequence ID" value="KAG0023076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N2S0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
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    </dbReference>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR24161:SF85">
        <property type="entry name" value="PALMITOYLTRANSFERASE HIP14"/>
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        <property type="entry name" value="Ank"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
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        <location>
            <begin position="95"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="146"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="217"/>
            <end position="275"/>
        </location>
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        <location>
            <begin position="318"/>
            <end position="391"/>
        </location>
    </feature>
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        <location>
            <begin position="447"/>
            <end position="479"/>
        </location>
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            <begin position="16"/>
            <end position="34"/>
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            <begin position="42"/>
            <end position="56"/>
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            <end position="231"/>
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            <end position="268"/>
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            <end position="334"/>
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            <end position="352"/>
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        <location>
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            <end position="469"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00012210"/>
        </source>
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        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
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            <dbReference type="ARBA" id="ARBA00023043"/>
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            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0023076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="569" mass="60982" checksum="6D44FA3FD5FE012B" modified="2023-09-13" version="1">MGPALQSPLDNPAPFTTTTATTTATTTTTTTSSTQSAPLQNTVATTSASSRVSSATNPNKKPFQNLGLHSGAASGNLGLVKFALDNGQPIDSVVNGVLPIHAACCSNANIAVVLFLIEHGSDVNARRQPRKYGGERAVGSQAVGTTGSTPLHFAAANGCQTVVEILLRHGAIADLADKALHYSNRVFSVAFIATTHHHNNHSAAARNLNQRRVSLPSIMESPSSPTAPSAPRQSCDLGRPPLSREPFDTASEPIIQTTSTNSPSSHSWGFSLRDKPHSSQNFASSLLTGRRKSVDISAMGPVSPPTVHKIHRRASLDQISAEKLMDSKSRRDSDVSISETVVSGPSSCSTLASPMMLGSNGSESLLDDSEEMRVMSSAESSSMERSLSQPSLPLEGGVIRRLPESNARKSFDLRLFASPRQQVIVNDDAKPQIWSYRRRSIQEPFLSNDNDEKFNYSSQEISPQGNGRNNGKHRTSFPGNATISGRLSRLWTNGPGRDIQENIVHRKGGSAGSIGLFEVEDGEDDVWSPNNLAKNSVNRVEMSPVNKEMGADKARVGVLSRFSGIWSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2W1</accession>
    <name>A0A9P6N2W1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_010115</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000067">
        <property type="protein sequence ID" value="KAG0023208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N2W1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051061">
        <property type="entry name" value="Zinc_finger_trans_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179:SF13">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="340"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
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            <end position="406"/>
        </location>
    </feature>
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        <location>
            <begin position="472"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
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            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
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            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
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            <end position="48"/>
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    </feature>
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        <location>
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            <end position="67"/>
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            <position position="1"/>
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    </feature>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0023208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="562" mass="63559" checksum="0CC4499DFC03ED8E" modified="2023-09-13" version="1" fragment="single">KTMSAFTFSHNSKPNPGQQQQSKPTHTSYFLITSRRVQQQQQQQQQQEQEQEHPTDTSASSSPSSISRDFVNMDLDGPGHVPENLQECPSRQHDHDQQHQVPYRSSSPVQRPISPNHPSRDPYYAHPHRPRYHPYDYDHKYYSHHSEHDLPAPHHDQEQKRAYDQSCQSHHQQYTYYRQKATSPSTADSTSPSPVPSASCSSASPSPKSLPMALSFSAKQSSDKAVKPHVNSSKAGDERSRSRSLFSPVDADTRTVPVSPSFSAMSGETSQHSAQRHPCMLPGCPAVLRSKQNLAEHVRVCKHKVVGQVLDSPEPSSDSPQPANNGQSRQNHKKQAGVKYPCPWRGCTKILATPKSLKDHLQIHAERDAGIQLYCPVPDCGKVFGTYRCLRAHELRCKQVKSGERLPCPYPDCRATFGSTDYVRRHVLDHEKGLIGVEFRCDYADCKAVLANPLTLQRHKQLHEEQSLGFQWMCLVEGCGKIYSGSKQLTDHQSRIHKSLDPNHRFACPYNKCEDLFDCQRAAYKHKCLYEKVTATPKKKKRQISAYALSFSRQLMLVPICN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2Z3</accession>
    <name>A0A9P6N2Z3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_009868</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000063">
        <property type="protein sequence ID" value="KAG0023298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N2Z3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="282"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="327"/>
            <end position="347"/>
        </location>
    </feature>
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            <end position="443"/>
        </location>
    </feature>
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        <location>
            <begin position="478"/>
            <end position="601"/>
        </location>
    </feature>
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        <location>
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            <end position="750"/>
        </location>
    </feature>
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            <begin position="793"/>
            <end position="870"/>
        </location>
    </feature>
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            <begin position="18"/>
            <end position="33"/>
        </location>
    </feature>
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            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
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            <end position="295"/>
        </location>
    </feature>
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        <location>
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            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
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            <end position="496"/>
        </location>
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        <location>
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            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="524"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
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        </location>
    </feature>
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            <end position="683"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="710"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="819"/>
            <end position="840"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0023298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="870" mass="91015" checksum="4793C96230A5E39B" modified="2023-09-13" version="1">MTPQVKDFEAFLALDAPATPPPFPPQQHTPLPPSQQHTPSSTESFFEDISNLEDTINDSTTTTTLATPNPFSNVPLSPIQLVAISNLKLNNDMYSNRSLSIHRRILVKNFLTLLYQLSPSIDWMQHNTYPGDAFEPLPGLDAPVPDEGDMLLREDEQNGWMERTLSAAGLNDDDDKVPLGISSKIQNTNPSATTKSSPTTITTTTTTATSSSSAPPLLTLSFNTSSSSSASSSSASSNKSQQATLPRPKSAELPQTLHSYLSTVFDVDWSVELPSKEDILFTHAPSTNPSTSSSSPSPPISSVASKRKSISAASGLSSAFTAYSNGNASSNSAPSASPRSSTSSSFSSVSATSTVSSASSVGSIGNESTILIGYNKPGELNNGNNNLMGATKATPAAAILVRKSSLTSLSKPAASSTQAVNNPPANNPPANNPPDNNSVNNINGVLSENRNLSVKKASINGHAKPTLVPGRRSSLLQAGKIPPALPSTKNNNTSNNMGVNGLARANSVATTGETANSLSPAMSLPPSRSPTSLSPPTLSPPTFSSASTSPTLSPSKPTSPALTPSLPTSPTLTPSKPTISRRTSSLPSERPKPVQRALSSESNFTLTANATTLSVPEANIIGLPRPLLSPTLSSAVLSSSPPSQPVMTTSPTSTTPPASGATRYMRSASDDQFTIRPNNTPYALNSFGVPEKSPSSPNLYSSPPPPPPSAQSGALSRPTASYLKTSKSSPCLAGPESVSWDKSSLPPLPDQYYQQQYQSQASSDMLTPSHGTMISAPLSLIPNNPSYNDYAGYDGHNHNNSNNNTRPYGHGREHSYAQSMSNVSVTSNSSVMTNNSSKTSRSQVSEKPAAGRWSSMKTMFGLRGGQSTKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N378</accession>
    <name>A0A9P6N378_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DDE Tnp4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_009012</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000051">
        <property type="protein sequence ID" value="KAG0023579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N378"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0023579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="55" mass="6528" checksum="423836C648D2AA9E" modified="2023-09-13" version="1" fragment="single">MGAAAVCDYIGRFTYFSTRYVDSSHDSSVYKRTFLYTNKDWFFQEDEYLLADVAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N404</accession>
    <name>A0A9P6N404_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Argonaute sirna chaperone complex subunit arb1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_011344</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000090">
        <property type="protein sequence ID" value="KAG0022738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N404"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033167">
        <property type="term" value="C:ARC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031047">
        <property type="term" value="P:regulatory ncRNA-mediated gene silencing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018606">
        <property type="entry name" value="Arb1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09692">
        <property type="entry name" value="Arb1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="339"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="343"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0022738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="489" mass="54947" checksum="079262C3BB4A484C" modified="2023-09-13" version="1">MDTSSMTEEQARETVSRMFEEMGKTLNGIGDYPESEYETDSEDESKKGTPARINTSSSTATGEAAGEDGEPKKKKKKKKKKKSNKPDLEDLLDNVEPDDKEEAYDINKSVAERVEIAITTFRKNRKFSNERAQIFSAYLDYGGIKTGPKSFQGGAVMGEEDGDPDYEAMKAGIDRVDDPEEGEEVDFTNVVTTFLSEHFLKNTGWIDMVYYKDTPLVVAAMLNYFLVRNVLPEYEQDIRGALAIAKKAQIELPLCKIISTGLPSRYDKACSLLYGGEFYGFLDDSWQDKQVLIDALGMDLPMAKRIVQSLIGPDTDLNSLTVGPREYMCLEVISVNMPQPTDDAADEVDSPTESPAEEDPELVAMVDKMLLGESQSQDGLSLETLSKNPIEPATDEVIIPIPMFADVTFAELDPDLPRDQQKPINQRRKVHVYFDPATASRILLEMRVDAYVYTLSNGMSYLQQAAVYPTFYLEREEVEIPWDEWEEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4F5</accession>
    <name>A0A9P6N4F5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Negative elongation factor C/D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">TH1L</name>
        <name evidence="8" type="ORF">BGZ80_009984</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NELF-D family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000065">
        <property type="protein sequence ID" value="KAG0023249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N4F5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032021">
        <property type="term" value="C:NELF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034244">
        <property type="term" value="P:negative regulation of transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006942">
        <property type="entry name" value="TH1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12144:SF0">
        <property type="entry name" value="NEGATIVE ELONGATION FACTOR C_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12144">
        <property type="entry name" value="NEGATIVE ELONGATION FACTOR D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04858">
        <property type="entry name" value="TH1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0678">Repressor</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="502"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="516"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="533"/>
            <end position="543"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0023249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="543" mass="61101" checksum="1A4E5547FA58CBA0" modified="2023-09-13" version="1">MATRNNAGGNSETSGVSSNVDMMMQSFQAPDSILEPKIFETIAAFIKEGGQPLLLVNALSNSYVGMPEMCNLMSGWARDFDLDPVEIMQEVLKEQLMERFDPESVDKDFMTGSGTPDWLLVMIQHPFWRSVIYELSEKHQKCALLNFAIQRISDAGYQGEIASVATASTFVNVFSGVLLDSLDKLREEDDVGLLDRLPDLVAATRIYSEDVIGGSIFDGSKCNFRYTSIPAYTSENPPSTYFLRDPDFFEIMLSSIFVPSFKGGMVKQDHKEKYLWLMAYAASVHEENDMITDKSEVQPTYEALSALEDTLSKRTAGTDLTPILGNLLVAIETPVASMALLYWIQFVIKETSYIETYFRSHEVPVPLLLIEEMAYKHPLQQAAVFATLVDFFEAPLELNPEIMMTYRKSILDRMIYLMQLNYVMPVLDYIQLRARKMDQSLSMHFVKKVLEMVRGPYSRKFIEGMGQMTQEIVEVIKKTDAEPIVRAWIDEVVAQSSDLEIQTPPALPTSATSHESGTGPSSSGDSGLATIQEVKRRLDEPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4Z5</accession>
    <name>A0A9P6N4Z5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_008350</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000045">
        <property type="protein sequence ID" value="KAG0023725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N4Z5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="61"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="116"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="193"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="61"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="79"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0023725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="279" mass="32440" checksum="27FC354184816C20" modified="2023-09-13" version="1">MAPSTSGLDLQLSYSGMQAVMTYWLHPSSLSPNIIQAIATEAALRMLARQSSESCITTVRSGSVLSKNPPEQSIKLSDDEAEDTNESDDDNEIVDNISEHMVEDLLVNRPTVDEFRSNTGELERKRRRRNDRGTPYQSIDTMSRFSTAAMIESTITGAVAESSLRYIEEARQDLRQRETESYQRMAENERRHQEMLDRRMQEFLEEKARQKQEFLEEKARQKQEFLEEKARQKQEFLEEKAKFKAKQEEFEKIRDRLIIENAAMKRELEIRLAPIPSQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N5Q0</accession>
    <name>A0A9P6N5Q0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 19">Mevalonate kinase</fullName>
            <shortName evidence="19">MK</shortName>
            <ecNumber evidence="3 19">2.7.1.36</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="primary">ERG12</name>
        <name evidence="22" type="ORF">BGZ80_004277</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="19">Mevalonate kinase; part of the second module of ergosterol biosynthesis pathway that includes the middle steps of the pathway. The second module is carried out in the vacuole and involves the formation of farnesyl diphosphate, which is also an important intermediate in the biosynthesis of ubiquinone, dolichol, heme and prenylated proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>(R)-mevalonate + ATP = (R)-5-phosphomevalonate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17065"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:36464"/>
            <dbReference type="ChEBI" id="CHEBI:58146"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.36"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="17">
            <dbReference type="Rhea" id="RHEA:17066"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="18 19">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via mevalonate pathway; isopentenyl diphosphate from (R)-mevalonate: step 1/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 19">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 19">Belongs to the GHMP kinase family. Mevalonate kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.36" evidence="3 19"/>
    <dbReference type="EMBL" id="JAAAID010000022">
        <property type="protein sequence ID" value="KAG0024315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N5Q0"/>
    <dbReference type="OrthoDB" id="1652964at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004496">
        <property type="term" value="F:mevalonate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006696">
        <property type="term" value="P:ergosterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019287">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, mevalonate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.890:FF:000003">
        <property type="entry name" value="Mevalonate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="entry name" value="GHMP kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013750">
        <property type="entry name" value="GHMP_kinase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006203">
        <property type="entry name" value="GHMP_knse_ATP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006205">
        <property type="entry name" value="Mev_gal_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00549">
        <property type="entry name" value="mevalon_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43290">
        <property type="entry name" value="MEVALONATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43290:SF2">
        <property type="entry name" value="MEVALONATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08544">
        <property type="entry name" value="GHMP_kinases_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00959">
        <property type="entry name" value="MEVGALKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="GHMP Kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00627">
        <property type="entry name" value="GHMP_KINASES_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 19" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 19" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 19 22" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 19" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="14 19" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 19" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12 19" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="16 19" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="13 19" id="KW-0756">Sterol biosynthesis</keyword>
    <keyword evidence="15 19" id="KW-1207">Sterol metabolism</keyword>
    <keyword evidence="6 19" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GHMP kinase N-terminal" evidence="20">
        <location>
            <begin position="116"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP kinase C-terminal" evidence="21">
        <location>
            <begin position="279"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00029310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00029438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="RuleBase" id="RU363087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF08544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAG0024315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="396" mass="42668" checksum="8F343F4E592A310D" modified="2023-09-13" version="1">MPSYFTSAPGKVILFGEHAVVYGKLATAGSLGLRSYALVQSRTDGALEVNLPDVQLVRSWKSADIPRQARWEGYPYPPPAMNVELLDQLTKFVDLGTQTNRSVAAIALLYLHSYLTSDDIANQGYDLSVRSDLPVGAGLGSSASYSVCLATALLKLNGHLSESLSAADQRDLVNQWAFQAEKVIHGNPSGIDNTVSTLGGAVIFKKGEKIEPLPGFQSLKFILTNTRVPRETQVLVANVRKLREKFPSVVNPMLDSINEISISCKQLFAQNGEDRAHLLSRFGDLVDVNHGMLAALGVSHPTLEKVREISSKLGLKSKLTGAGGGGCALTLVRDDMDEKTVEELKTKLGEQGFEVLEAQVGGPGAGFVTLDSVTSIAEFLSRGTADLETQTWTYFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N6P5</accession>
    <name>A0A9P6N6P5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_002428</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000016">
        <property type="protein sequence ID" value="KAG0024477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N6P5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="192"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="296"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="363"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="400"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="621"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="713"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="833"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="883"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="140"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="196"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="224"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="327"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="375"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="400"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="479"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="549"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="587"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="621"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="713"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="735"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="747"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="767"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="781"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="843"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="857"/>
            <end position="866"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0024477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="961" mass="106001" checksum="A0F68026673E5076" modified="2023-09-13" version="1">MLNSPPSLPGQLMNFQRNSGHEAELGQVDDDPHGAAAMALTALSSGMGITSTAKHSLKATQSHLSIASGTMVGLGLEMTEGTATASRNLQESSPSATVARMSHSDNKAQTVQLNERRILTKASNEGGAVAMAVAGIMQSRQQTITEHSQPQPTCEPPLPESETIRLHPASHVPGERMQTLSHLLKDQLSLASMRSDQGKERDRTGSGRCNLLRHDDVASGTYEEDGRSPAHNSREDSARMYTEHRLYHQSISSPNLRLLTEETRQLDGMRYQRGMIEHTSLAAEWQQPIRHYENSYSPKGIRPLDQNSTSPLTEPEIAKPKRKYTKKTTVSPSLLENPNQEASHAVQEGELLQSDRGLILKTQIPKKGRPISKHSSISQSTPTLSSLGVLPASHPYFSSKTGISPSSSAPSFRPPDSNRSPLANYPRNPGYPPLTATTTDEFQPHAPIRRRPGRPPLASTIARHAHSQSHSSLQPGPFSASKSQSRSARYSSRDVHGRPPPPLSTPSPSMSVGISAIKSRHNRRSYPSSQGHEQLPVLESQHRIAAHQTEYEHPNEDWRFQNSHNGETLPSPGPASFAGGIPTQTNGRERGSYGAEKRQSTDDLYCLENERRGTSSVYDIKERQDEHYQDHAKDKRSKRRLTISDMDSVGSETNTLDGNETVQGWLDYGSEYRSRPRSLMLPRGISDSLLQLQSVTARTTDAACISELRHRTSGLDDDREMSEHRDSEMPITRNATRRSLHGHTRSLDLSSRSLFSLDYHPQPSTERAPESQSKSDDQAFGRSNSDSNIYSYSTSPPPLLTHVQYGKDYSTATNMQPYPSSSIDYQGYSLEPSETTRADELASKMSAGSSRGSKSRTGTISAQTKTSSKRLSRRGPGSYLKKHEILQMQLQQMQREQEEMEAQLVLQRQQELYQLQQRYSLESTPTANTSTAATSTVVSTKTAAKPPSAHIATTSFVAFIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N6X3</accession>
    <name>A0A9P6N6X3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Profilin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">PFY1_1</name>
        <name evidence="8" type="ORF">BGZ80_002767</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Occurs in many kinds of cells as a complex with monomeric actin in a 1:1 ratio.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the profilin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000017">
        <property type="protein sequence ID" value="KAG0024453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N6X3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003785">
        <property type="term" value="F:actin monomer binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00148">
        <property type="entry name" value="PROF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.30:FF:000001">
        <property type="entry name" value="Profilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.30">
        <property type="entry name" value="Dynein light chain 2a, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048278">
        <property type="entry name" value="PFN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005455">
        <property type="entry name" value="PFN_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036140">
        <property type="entry name" value="PFN_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027310">
        <property type="entry name" value="Profilin_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11604">
        <property type="entry name" value="PROFILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11604:SF0">
        <property type="entry name" value="PROFILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00235">
        <property type="entry name" value="Profilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00392">
        <property type="entry name" value="PROFILIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01640">
        <property type="entry name" value="PROFILINPLNT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00392">
        <property type="entry name" value="PROF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55770">
        <property type="entry name" value="Profilin (actin-binding protein)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00414">
        <property type="entry name" value="PROFILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0024453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="127" mass="13925" checksum="C3F25DB0817025D3" modified="2023-09-13" version="1">MSWQAYVDENLIGTGKVSKAAIFGLDGGLWAVTPGFSIEAAELDKLIKAFDDANDVQEKGLYLEGQKYYYLRSSHNSVYARLGTTGVTCVKTNQAVLVGYYDESKQKAGECTMVVEALGDYLRSQGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N794</accession>
    <name>A0A9P6N794_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Presequence protease, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Pitrilysin metalloproteinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="primary">CYM1</name>
        <name evidence="17" type="ORF">BGZ80_008905</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Degrades mitochondrial transit peptides after their cleavage in the intermembrane space or in the matrix, and presequence peptides; clearance of these peptides is required to keep the presequence processing machinery running. Preferentially cleaves the N-terminal side of paired basic amino acid residues. Also degrades other unstructured peptides. May function as an ATP-dependent peptidase as opposed to a metalloendopeptidase.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer and homodimer; homodimerization is induced by binding of the substrate.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion intermembrane space</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase M16 family. PreP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000005">
        <property type="protein sequence ID" value="KAG0024747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N794"/>
    <dbReference type="OrthoDB" id="10250783at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000013">
        <property type="entry name" value="Mitochondrial presequence protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000009">
        <property type="entry name" value="Presequence protease, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000011">
        <property type="entry name" value="Presequence protease, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.830.10">
        <property type="entry name" value="Metalloenzyme, LuxS/M16 peptidase-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013578">
        <property type="entry name" value="Peptidase_M16C_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055130">
        <property type="entry name" value="PreP_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43016">
        <property type="entry name" value="PRESEQUENCE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43016:SF13">
        <property type="entry name" value="PRESEQUENCE PROTEASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08367">
        <property type="entry name" value="M16C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22516">
        <property type="entry name" value="PreP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01264">
        <property type="entry name" value="M16C_associated"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="LuxS/MPP-like metallohydrolase"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="13" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7 17" id="KW-0645">Protease</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M16C associated" evidence="16">
        <location>
            <begin position="499"/>
            <end position="746"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00020167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00034552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00045897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM01264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0024747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="987" mass="109909" checksum="1A320EC1E3B1AFFD" modified="2023-09-13" version="1">MLAATRVAALRKSIAHASPSFRQSQRACLASLSTAESWKPGKSIHGYTVLETRHVKELELDAIRLKHDKTGAEHLHISRDDSNNVFGVGFATPPDNSSGVPHILEHTTLCGSRSYPVRDPFFKMLNRSMATFMNAYTASDYTLYPFSTTNPIDYKNLRNVYMDAAFFPHLRELDFKQEGWRLEHENPNDPSSPIVFKGIVYNEMKGQMADAGYLFWSKMQQHMFPGTTYANNSGGDPANITDLTHEELVHFHRTHYHPSNAKFYTYGNFALEDSLEAINSKLQEFSPITPPLAEKVVKPFGSPRRVGLTCPVDPMSLPEKQVKMSVSFLTNKATDTFEGFGLRILSDLLTDGHASPMYKALIESGLGSEYSANTGYDGSTMVSSLSFGVQGMKQDDVSKVEETITKVLHKVKEEGVDPKRIEAIVHQMELGQKHKTSFFGMSLMQGLSSGWFNGCNPVDLLELNKNIDRLKAEIAAGPFFQNLISKYLLDNPHKLVFTMTPSPDYGAEVAANETTRLMGKTSVLTKADKETIYQQGQELLKNQEKVEDVSCLPTLKVDDIAKKTKTFSLEHSAVNSVPVQWRPTSTNGITYFRGISVIPGLSAEQKKYLPLFTDSLTSLGTHKRAMSEIDDDIRLYTGGIRVSPFLSTNHSSIDMTEEGVSFSSYCLDRNQDYMYDLLGSLIRETNFDNVDKLRTLIQGNASGLSNSVADSGHVFARTNAGSRLTPAGSGSELYGGMTQVQFMNSLSQKEDLSEVSQRLKEIAELAIKRSSMRLAVTCGEDQMSRNENVVSQFISRLDNKSVDSITQPEFVPTFENSFFELPYGINFTAKCLRGVPYTHEDGPKLQILASLMSNLFLHREIREKNGAYGGGAGFSPTGGLFSFYSYRDPSPKKTLATYQDSVRWALDRADFTDQELAEAKLSIFQRMDAPVSAADEGMVVFTEGITDEMRQTRRERLLKVASSDVKEVASRYLLDQPSSHCILGDKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N7L9</accession>
    <name>A0A9P6N7L9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GDP-mannose transporter</fullName>
            <shortName evidence="5">GMT</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">VRG4_1</name>
        <name evidence="7" type="ORF">BGZ80_000014</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homooligomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Golgi apparatus membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Cytoplasmic vesicle membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Endoplasmic reticulum membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TPT transporter family. SLC35D subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000001">
        <property type="protein sequence ID" value="KAG0024886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N7L9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030659">
        <property type="term" value="C:cytoplasmic vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00803">
        <property type="entry name" value="nst"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="147"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU367097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0024886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="184" mass="19891" checksum="8C5CB6FD17187A69" modified="2023-09-13" version="1">MRRRIKHFNFQDFDTVYYNNLLSLPVMLVLSFCLEGWTSGEFERTFAPEVRSPIITAILLSGISSFLISYGSAWCVRCTSSTTYSMVGALNKLPVAASGILFFGDPATLGNIFGIFFGFIAGLLYSYSKTEQAQKNFALANGSPLSTTSSSGAELAQLRTPAVPPSKATGLPLYNSNPDGKIAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SQN2</accession>
    <name>A0A9P6SQN2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008740</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004849">
        <property type="protein sequence ID" value="KAF9992049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SQN2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9992049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="131" mass="14928" checksum="EE44789E59F394E1" modified="2023-09-13" version="1">MTELYQLMVRKLWRKDALRLGKSAGGRTLTPQEISQLRPKEVDEVMDTEMQLLGYLAFKGMENNHQIEFDEETLRNAFGDVRAAFKIDLFPSQLLENMKQTSFLHTADADVDNNRNGSQQACIMDSPASTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SRM2</accession>
    <name>A0A9P6SRM2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004241">
        <property type="protein sequence ID" value="KAF9993769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SRM2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05729">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NACHT" evidence="1">
        <location>
            <begin position="73"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9993769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="329" mass="38469" checksum="CA715E55D5B65E3F" modified="2023-09-13" version="1" fragment="single">MAFYLPPKEFLLLDRVQDKPDLRSPLLQLKSNRLKDKNADVYISPKAKSSLRATETFDLMSEVQEFLQSKKKVFLLLGDSGAGKSTFNRALEISIWERYGKEETRIPLFIHLPLIENPERNLVTKQLQRLDFTEIQIKELKEHHKFILICDGYDEIQQTKNLYEMNQLNKPGEWQVQMVISCRTEYNGVDYKNKFQPTERNSGGDKDQFQEAIVAPFNEGQIQDYVKQYVSLKNQQNVSSDDTHWELEEYQQALKEVPNLLDLVKSPFLLKLALKVLPGLFNKNSKFSAAHITRIGLYDKFVSQWIERSEIRLRGMELSSHDKDHFHTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SRP9</accession>
    <name>A0A9P6SRP9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_007944</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004177">
        <property type="protein sequence ID" value="KAF9994012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SRP9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9994012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="168" mass="18888" checksum="CB45441EF757C347" modified="2023-09-13" version="1">MLFGQTASSYALSLPELVVEIGQYLTNIEVIGALQVCKGWHALLQPLLVQDVFISYTEDVLPPLDLLARYSRKIRTITIIGRPGRHRIEYFDLRGCTVLNPVPRLSSLSLRHIELSEGSAHYFWAGCRELEDLEIGNCDDLRHVRSVYTDLKAAAVTLQEKLDAGVHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SSG3</accession>
    <name>A0A9P6SSG3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_007096</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003578">
        <property type="protein sequence ID" value="KAF9997035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SSG3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990234">
        <property type="term" value="C:transferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847:SF637">
        <property type="entry name" value="WD REPEAT DOMAIN 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="121"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9997035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="133" mass="14385" checksum="B2DACC26FFCDB958" modified="2023-09-13" version="1" fragment="single">VVYSPNGDQIASGSDDNTLKLWSVETGQCLSTISGFSNAVSSIALESSSGVQHLVTGSFDKSVRRWRIIEEGAKHKAVLCWSSSHEVLTVYDLCFEGVQDLSSLNRELLIQRGALTPTHPGPDRESVDKPKPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ST85</accession>
    <name>A0A9P6ST85_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Phosphotyrosine protein phosphatase I domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_006543</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10684"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:20101"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:61978"/>
            <dbReference type="EC" id="3.1.3.48"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the low molecular weight phosphotyrosine protein phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003235">
        <property type="protein sequence ID" value="KAF9999571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ST85"/>
    <dbReference type="OrthoDB" id="3388at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004726">
        <property type="term" value="F:non-membrane spanning protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16343">
        <property type="entry name" value="LMWPTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2300:FF:000105">
        <property type="entry name" value="Low molecular weight phosphotyrosine protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050438">
        <property type="entry name" value="LMW_PTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023485">
        <property type="entry name" value="Ptyr_pPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036196">
        <property type="entry name" value="Ptyr_pPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002115">
        <property type="entry name" value="Tyr_Pase_low_mol_wt_mml"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017867">
        <property type="entry name" value="Tyr_phospatase_low_mol_wt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11717:SF7">
        <property type="entry name" value="LOW MOLECULAR WEIGHT PHOSPHOTYROSINE PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11717">
        <property type="entry name" value="LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01451">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00719">
        <property type="entry name" value="LMWPTPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00720">
        <property type="entry name" value="MAMMALPTPASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00226">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52788">
        <property type="entry name" value="Phosphotyrosine protein phosphatases I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphotyrosine protein phosphatase I" evidence="8">
        <location>
            <begin position="13"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="19"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="25"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00051722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR617867-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9999571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="117" mass="12889" checksum="9DAC3129BB436B0E" modified="2023-09-13" version="1" fragment="single">MAANGNTNSSNTTKVLFVCLGNICRSTMAEAVFKHAVEKRGISTEFEVDSAGTASYHVGASPDSRSAETCRKNGVPMKHRARQVTNEDFTKFDYILCMDEENLRDLKDMAPKGHKSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6STF7</accession>
    <name>A0A9P6STF7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UBC core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_006229</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003067">
        <property type="protein sequence ID" value="KAG0001140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6STF7"/>
    <dbReference type="OrthoDB" id="9973183at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23812">
        <property type="entry name" value="UBCc_ScPEX4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="2">
        <location>
            <begin position="4"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0001140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="161" mass="18069" checksum="FD62C29D702D42DD" modified="2023-09-13" version="1">MSSAVHRRMLKEYLAIQKNSATRPHLEVLEPVQEDDLLHWRAILLGTADSAYEGGRFKLDIVIPTNYPIQPPTIRFVTTICHPNVHFKTGEICLDILKSEWTPSWTLEAICVAISSLLTNPEPSSPLNCDAANLLRCGDIAGYNSLVRMYTGKFAIDEEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6STK3</accession>
    <name>A0A9P6STK3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Translation machinery-associated protein 22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_006225</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eIF2D family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003064">
        <property type="protein sequence ID" value="KAG0001171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6STK3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001731">
        <property type="term" value="P:formation of translation preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11608">
        <property type="entry name" value="eIF2D_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21156">
        <property type="entry name" value="PUA_eIF2d-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.780.10:FF:000008">
        <property type="entry name" value="eukaryotic translation initiation factor 2D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.400.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.780.10">
        <property type="entry name" value="SUI1-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.245.10">
        <property type="entry name" value="SWIB/MDM2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039757">
        <property type="entry name" value="EIF2D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039759">
        <property type="entry name" value="eIF2D_SUI1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041366">
        <property type="entry name" value="Pre-PUA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048248">
        <property type="entry name" value="PUA_eIF2d-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001950">
        <property type="entry name" value="SUI1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036877">
        <property type="entry name" value="SUI1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058886">
        <property type="entry name" value="SWIB_eIF2D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036885">
        <property type="entry name" value="SWIB_MDM2_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003121">
        <property type="entry name" value="SWIB_MDM2_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004521">
        <property type="entry name" value="Uncharacterised_CHP00451"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057429">
        <property type="entry name" value="WH_eIF2D"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00451">
        <property type="entry name" value="unchar_dom_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12217">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12217:SF4">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17832">
        <property type="entry name" value="Pre-PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26292">
        <property type="entry name" value="PUA_elF2D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01253">
        <property type="entry name" value="SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26291">
        <property type="entry name" value="SWIB_eIF2D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25304">
        <property type="entry name" value="WHD_eIF2D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55159">
        <property type="entry name" value="eIF1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47592">
        <property type="entry name" value="SWIB/MDM2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50890">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50296">
        <property type="entry name" value="SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51925">
        <property type="entry name" value="SWIB_MDM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DM2" evidence="5">
        <location>
            <begin position="420"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="domain" description="SUI1" evidence="4">
        <location>
            <begin position="526"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="200"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="215"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="249"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0001171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="618" mass="68498" checksum="FECB3E4CAB36B020" modified="2023-09-13" version="1">MFKKPVASLKSFSPLRSSDKRRLRDEIIAAFPSFKDMDPIDDTPINAIITPDGLQSAKFTSYIDEPGTLYTDPHGTPLWFKISTPAKKDSLIVPSIYTLWKFPTLIPALTTWNPVLDKLRNGADLMIPGVITAAGTPVPDLHEGALVVVLARGNKYPLAIGTMAVSGQAIASSRGSQPPKGKAVHILHVHQDQLWAMGPKSELPSDWSLGKVPLDDEEYESSNEDNDGNDTDNDDSLAKDMNTVSVTESKGKEPARDEPIADTEPIIPESNENQPTHPAEEAIVLSTEEVDKYLHDALLQVLKFKITEDVSKELLPMNASTLYSSYVLPNRAPGRAAEADIKKSSWKKAAKWFKAVEKQDLVKCKEIKGELFLLSVNWNHPQLKEFKGQKTVEQQAARQAKVEAKISQENAAVKSLEVLEAYRPNSTSSGLFEATGRSKDGYYSLQELRAMLAAYIKEKQLSDPKNQRFIRPDEILRAALSKKGEQLDRVPRDETSDRLVNNMVHHHFIGYKDQQPRFVKGGIKPIQIVQEIRSGRKTVTKVSGLELFLIDVDAFSQEIQLLCASSISITPLVGASPKLNLKEVMVQGPQSTNVTSVLISKGVPKKYIEFVDKTSKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SUQ2</accession>
    <name>A0A9P6SUQ2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">1,3-beta-glucanosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">PGA5_2</name>
        <name evidence="10" type="ORF">BGZ80_005535</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002725">
        <property type="protein sequence ID" value="KAG0004918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SUQ2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF1">
        <property type="entry name" value="ASPARTYL PROTEINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 8" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0865">Zymogen</keyword>
    <feature type="domain" description="Peptidase A1" evidence="9">
        <location>
            <begin position="1"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0004918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="264" mass="27262" checksum="92879907C0D606C3" modified="2023-09-13" version="1" fragment="single">KDGRSWSISYGDGSSASGTLGSDIVSVGGISVRQTIGLATKESSQFGSSPEDGLFGLGFASIESVSGVLTFMDNAIAAGVVAEPVVSVFLPSERVFNGEGGEYIFGGIDSSKYTGSLTYVPVTQEGYWQISVDDIGYNGQSLGQSSQGIVDTGTTLIIVGDDAAQAIHDNIEGAYNDYENGWIVPCSLQSSSDSISFSMGGSSFNVAIADLAFEDLGDGSGNCFSGVQGGQDDLWILGDVFIKNNYCVFDHGNSQIGIAPLAGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SW54</accession>
    <name>A0A9P6SW54_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004003</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002097">
        <property type="protein sequence ID" value="KAG0007972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SW54"/>
    <dbReference type="OrthoDB" id="2318892at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040295916" evidence="1">
        <location>
            <begin position="26"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0007972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="159" mass="18216" checksum="EDA2617093F62694" modified="2023-09-13" version="1">MIPMRQVFTFAFLHVLALFAKSATASFAYCVGVNGPLTLGREVVGFKLWNDRGEEPEQYRSIYFAKKTTMRNDGWSLDLKFDTPVYLTLRNISVSSDLYGNVGNVGFHHICGFKSKTLYYGCYSNDNSGFCERNEDAYMDYCYRRLPMGRDVSSEVYYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SW81</accession>
    <name>A0A9P6SW81_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004125</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002138">
        <property type="protein sequence ID" value="KAG0007877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SW81"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0007877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="124" mass="13766" checksum="7FD2B167092A8255" modified="2023-09-13" version="1" fragment="single">MEGKTATNKGWSQIWDDLTKLGQELKHSLDTMIVQEPSGPVIDSSMEADTPSISESDGQDNESDERREQELFNLMNAPLAPVSRDPFKNTSPPASSEEIETVEYKSLGNMNVQCAQCSALMWNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SW90</accession>
    <name>A0A9P6SW90_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">dihydroorotase</fullName>
            <ecNumber evidence="3">3.5.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_004080</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 3/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.3" evidence="3"/>
    <dbReference type="EMBL" id="JAAAID010002121">
        <property type="protein sequence ID" value="KAG0007916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SW90"/>
    <dbReference type="OrthoDB" id="1670005at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004151">
        <property type="term" value="F:dihydroorotase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006221">
        <property type="term" value="P:pyrimidine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01294">
        <property type="entry name" value="DHOase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.140:FF:000071">
        <property type="entry name" value="Dihydroorotase, homodimeric type, variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00219">
        <property type="entry name" value="PyrC_classII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004721">
        <property type="entry name" value="DHOdimr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002195">
        <property type="entry name" value="Dihydroorotase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00856">
        <property type="entry name" value="pyrC_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43137">
        <property type="entry name" value="DIHYDROOROTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43137:SF1">
        <property type="entry name" value="DIHYDROOROTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001237">
        <property type="entry name" value="DHOdimr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00482">
        <property type="entry name" value="DIHYDROOROTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00483">
        <property type="entry name" value="DIHYDROOROTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="8">
        <location>
            <begin position="69"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0007916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="351" mass="38686" checksum="3CFE7603DB48CEC8" modified="2023-09-13" version="1">MDTITIPTASDMHIHLRQGSLMSMVTPAVQEGGVSICYVMPNLQPPVSNTEMALAYKAELEKLAPKVTFLMSLYLNPSLTPEEIRKAAKAGVRGVKSYPRGVTTNSESGIESYDIYYPVFKAMEEEGMVLNLHGEIPSDAEKNVCVMNAEEKFLNHLKDIHLAFPKLKIILEHATTEAAVNMVKSLGETVGCTITVHHLQLVVDDWAGKCHNFCKPVAKYPSDRAALRNVIKEGHPRFFLGTDSAPHPSHKKEGPEACAGVFTTPLVLPYLATILESFGALDRLKGFACDFGREFYEVKNEKWVGQVTLTRESWTTPQSYSFGGAGIEVEQGDVVPFMAGKPLAWKISKIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWI8</accession>
    <name>A0A9P6SWI8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="6">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">PPG1</name>
        <name evidence="8" type="ORF">BGZ80_003357</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4 10">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the PPP phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="6"/>
    <dbReference type="EMBL" id="JAAAID010001883">
        <property type="protein sequence ID" value="KAG0008510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWI8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07415">
        <property type="entry name" value="MPP_PP2A_PP4_PP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047129">
        <property type="entry name" value="PPA2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45619">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF033096">
        <property type="entry name" value="PPPtase_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0464">Manganese</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="7">
        <location>
            <begin position="109"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="5">
        <location>
            <position position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR033096-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0008510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="393" mass="43811" checksum="6ACE8067556DB41D" modified="2023-09-13" version="1">MVLDLDACIDSLFQRQLLAESVIKEICEKTKELLMSESNVVHIKAPVTVVGDIHGQFYDLLEIFKIGGYCPDTNYLFLGDYVDRGLYSVETMSILTCLKLRYPDRVQLVRGNHESRAVTQTYGFYTECMKKYGSAQVWHYFTDLFDYLTLSVVIDNMIFCVHGGKALELRSLFDSGIKQQTNVFKELFADEILIGPCYSLEKPLGLSPSIHTIDQIKVMDRFKEIPHEGPMADLVWSDPDPGREEFAVSPRGAGYTFGSLVVEKFLHENGMDHILRAHQLCMEGFQVLFDDQLSTVWSAPNYCYRCGNLASILEVGVEGERHFNVFEAAPENERPTAEAQRTLFSNGIPTSLYGNGVGAGAAINGVGGNDTTASGFLNPGGIDSAQDTIHYFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SX25</accession>
    <name>A0A9P6SX25_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">VPS9 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_002530</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0507 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001629">
        <property type="protein sequence ID" value="KAG0009299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005769">
        <property type="term" value="C:early endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030133">
        <property type="term" value="C:transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097422">
        <property type="term" value="C:tubular endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045022">
        <property type="term" value="P:early endosome to late endosome transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.80">
        <property type="entry name" value="VPS9 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051248">
        <property type="entry name" value="UPF0507/Ank_repeat_27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003123">
        <property type="entry name" value="VPS9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037191">
        <property type="entry name" value="VPS9_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24170">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24170:SF1">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G09870)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02204">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109993">
        <property type="entry name" value="VPS9 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51205">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VPS9" evidence="3">
        <location>
            <begin position="507"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="101"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="516"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="706"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="952"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1019"/>
            <end position="1052"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1068"/>
            <end position="1114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1150"/>
            <end position="1190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1229"/>
            <end position="1305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1334"/>
            <end position="1355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="25"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="129"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="151"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="526"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="708"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="774"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="788"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="824"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="953"/>
            <end position="963"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="976"/>
            <end position="987"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1039"/>
            <end position="1052"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1094"/>
            <end position="1114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1236"/>
            <end position="1255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1256"/>
            <end position="1280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1288"/>
            <end position="1305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1334"/>
            <end position="1343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0009299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1468" mass="158948" checksum="139641EB037B8640" modified="2023-09-13" version="1">MSASTKKSSGFTTKTPGRRTKRTSAHSISSTITNSGMPASRRVSCADTASQNSATFIDDQDVEVDENSFYIHLQKMQDRFQAQQEPGWLRTQHAILQAKHRLPGSGSPQPDQRGSFGGKKPGLFTRIHSGSSSPNSSDYSSSPSFHLGPQHSRQSNHGGVSSQRHQPILPLNCFQPGNVICVPRERTLGGLVFHKTFVDTHILTPSPYYQAQYLTLDHKVVEIDRDYVREISGFSHPRSVQILGEEMVYNGASKKPTRVLILERPLEGDGIVQARAIEGPMMPNLRQFTSDLAFIESFPELSRALRDFNNLCQEFENTYVYIRGFATHTLEKLRLIYEKAYRDCVGDSVKLQKILNQGVQAEQDCFAELMENIVLGKLYQKLFIHSLMPCYAERDVHLDDIIAKYHRYLFGVGSHRGIDGGACLAATDNPLLQEALKKLGLSEKWRNMRVDYALDGAAGLLRAWDRGDQDGSSPLSLSSQRIAAANLLQESEQERKRRQLRESLRVFVQDDKYKSGKRSLNFDPESHEDENETSNEDEGEEEEEEKVQDDLTANAVWNTPLEKAYCIKLVLDKIAIVAEDHLANGHGFGFVQKKRSQVSVTTDDFIPLLAIVIIQAKMMHLGSNMFYVQRFRINTPKPDLSFALVTFEATIEFLKKDPLGLLGTGQHTMSSSTSLGSGSRTYLHGSQSLLEGDKVSFSEEVQALPWGTPSQTGWGFSPPRASSETHTLEQPNPERSIHATLSESSPARPPFAIRPSDNSQQDQQRHARSASVNFDDRVRRVAQAEEAGSGSSNNSSWSRSPMLGPRFTSGANSPLALASPTYGVLSSPTESGSGPTARRPSHQLTHMPQRHSISNGQAHMIVHAQHNHYQNRFSLDQGRDSIGRSTLKPLPSPNLTPQLVVKPQIMLPPPPKTPPMSGQNTTGRARPMSMIAAGALASSGYSSSYGGSGAITSRRSFSSNQSSPATSPRLGPGIGSRQSNSRSNSLMSGPFPMVRANSMSTVITADELSDDINAMLKDTEQTESSSPVSPMSPWAQATMQPSPQSPLLSSSPALMESSALTELPAGLVVPQTPEGPKLSSNRSGATTPGRIRVSPSMTLSSISTPTTPSTFSSASGSALLESLNSNSQLASPSTSVSIATPASLVAGLSAIKPSPGHETATHPHSSTPLSAPGNVRSESNADEQTSARRHLPRLSLSLSHSSSAPSTAFCKTTVTAAATHATTSVDDLEPTSTVLATDPVTPPTSSSATASGRSSINHDGRSSSGARMKETSALHQKADSSKYAGYRSGSASHSSNHSTSSSKSYNSVGNNVIEHFSHGTALDFEQGFRDDLCLDPRNSDRRRGSATSLRDAKSMGSFQPEKVIMIWNQNPTGSFVDGHNGGGGGQRVGAVSAKRLTISGGDLLSSSHSSSSPYNYQRPFSPIASSFTIEDPQQRTREMMGDFLSELAKVEDGDVLVGNGRDGVMTRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SY29</accession>
    <name>A0A9P6SY29_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_000987</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001218">
        <property type="protein sequence ID" value="KAG0011051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SY29"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0011051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="278" mass="31530" checksum="C3EEA199D5A307F2" modified="2023-09-13" version="1">MKLDSVMTDDGFDFDLILSTSEEPSVSSQHYLNHAYHLSVMTTLMSDIATTDMIFTFPSTAEGRCIGLCAHQAILQKHEKLSALLSKLAEVKVSCSIEGSENEYSLPVKMLSIPSFSLEAFCCLIRFLYTGVIDLEVKPDLFSIIEVEARQLLPVTRTKEALAQSRSRLSPMKTVSWDELFELADCYGTKNLREYCRQKILASIKKEQVIGMLFKIGRFHKDLKQLMLDYIADHYEELFADSADPFLEHMHDANSHSLFVEALHCYLEGKKKNPPLSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SY52</accession>
    <name>A0A9P6SY52_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_001093</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001244">
        <property type="protein sequence ID" value="KAG0010908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SY52"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0010908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="52" mass="5729" checksum="C748EA96F7B651EC" modified="2023-09-13" version="1" fragment="single">KFSVMAPFSNDDIEGIATSFKEMVVVVDAVEEVEEGGVVEDEYRDADQDSMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYB3</accession>
    <name>A0A9P6SYB3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001455</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001330">
        <property type="protein sequence ID" value="KAG0010480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYB3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="380"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="589"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="86"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="388"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="590"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="622"/>
            <end position="640"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0010480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="780" mass="85544" checksum="DB298C63FFEF3799" modified="2023-09-13" version="1">MGILSSILKLYPGRRLAPNPLAVTTGTNTILATTNDHGNHDSNDVSGNAKEYNLVSQSELSGDIYSEECSIASLTAEMDIALSSSLVHSPGSSTSAPPRASASGIPTSEPNWSRRIPNAITCTDTAGAMLSISRSTLIRPSKRRQESDLTSDIEATVMAMEIDKDISKADTLNGVASEGRHDPKNNDALKQVYPLVQNRMFDIPEIIRSIAEFLDKPSLAASCRVSRVWATHCAPLLWKHVGDKHWLDGRFYASVRSNAHFIRTMKCEDKTDYEEVLFCQLPRLRALSFHGDKENIAVKVKILSKVCDTLTSLVLSSVSDVLSLDTAVAVRNMKRLTTLKLQNMRLQRKQLAEILSDCGDLEFLSLSRVRLTLGSAQHEDDDLEASDDTSTTTDTGNEQSTEVTRIKYLALKEISVSASYITKMIKSCPQLLELSLARNENLAITKDIIQAMADFCPNLYALDLGSCKKIDQGQFNALFTSITQLTVINLSGTRVGDDQLLLLAENCNSITRLDIQYCTSITSEGLHRFLSHCGPSLRHLEAAGVTIEPKSFDQRHWTCTNLQILFVHVGLVGSVAPSKATLLNGLATEENGNSNHSSSTPSIGNGALEVTGNERKRPQYAVSASSSTSDYQGSSHGTQDATAVSATTVSTWNTGISMEATSASPSKEAAIIHTESDGDVIMRHPLHPVQEVSKVQYLGLMGCGPKLTCSTRNMLIQGFRSVKRLHVLGLYQAFKKEDLEWLMENLPELCRIDAEKYNVSDELLKWFEVAYPHVQVCRQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYD9</accession>
    <name>A0A9P6SYD9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Zf-C3HC-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_000752</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001164">
        <property type="protein sequence ID" value="KAG0011346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYD9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013909">
        <property type="entry name" value="NuBaID_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012935">
        <property type="entry name" value="NuBaID_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15835">
        <property type="entry name" value="NUCLEAR-INTERACTING PARTNER OF ALK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15835:SF6">
        <property type="entry name" value="ZINC FINGER C3HC-TYPE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08600">
        <property type="entry name" value="NuBaID_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07967">
        <property type="entry name" value="zf-C3HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3HC-type" evidence="7">
        <location>
            <begin position="131"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="NuBaID C-terminal" evidence="8">
        <location>
            <begin position="294"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="24"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="87"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="191"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="24"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="87"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="191"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0011346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="412" mass="45471" checksum="39C06BE4BD1E683F" modified="2023-09-13" version="1" fragment="single">MDTKRKIEESLALLNSIIAHPNKKQSIAHQASNTATDSLPGSAPGGTSPASFKKRVYLPPRPAVLDKLSRLSSSRPTLRDSIAASIAASAPSSNSSPSDPTAPTSVSSSVSQPCVAKTNAPLNPSKKKYMPWSREQFHERLETFKPSTWFDKPKIVSPVECAKRGWINKGNDRLECFGGCGGVVIVRVDQDQRKADHKQSQDSAGNDGGEPRADVIDDDGDADDMLYELGIEDNIYKFPVVSLSQARAELLDRVKFLTFMENDCLIEKIRHPLTQNQIESLESRFPDVASTKLLILSLFGWSTLDEQRMLFCKACHTRCTYIISSGFSGSDSSNRVGMDEDDIMEEEDEVAFDVVQSHKWYCYWVNMEQDSSHKEGWRTLFERLTYAATGKINGGDGSAESLQSGSSTAKIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYP0</accession>
    <name>A0A9P6SYP0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_000505</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001103">
        <property type="protein sequence ID" value="KAG0011690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYP0"/>
    <dbReference type="OrthoDB" id="2383397at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="99"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="134"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="229"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="193"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="239"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="267"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0011690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="293" mass="32490" checksum="DD6962639678311C" modified="2023-09-13" version="1">MVQARRFHSNFLFIIPLTQGVLLITILDFCKNAVFFGNQVQNLSPNTYSSIGNGQQLVRRKDSAYLAAQYLYTIWLIAMMVKAIIGFRANLKFNIRWMGIYNILFGIDTGFEFIHTTLGIIFQDTSQLDDADIINRYCVSFLILIIQIYGFICCWMHLRWVHAEMPHLITPTSPRETFFEMMVPTALRRSRGTHATGRAIATTTTTLDPEEPEPSMVEAGLAPVAVQRASTVPGAEQAPDSSLTSPSLSTFDSSRIHQTNVSPVTEASAGAGAAQTSSSARNEESEIQVVSQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYU6</accession>
    <name>A0A9P6SYU6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_011707</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000977">
        <property type="protein sequence ID" value="KAG0012475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYU6"/>
    <dbReference type="OrthoDB" id="40902at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05117">
        <property type="entry name" value="STKc_CAMK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000153">
        <property type="entry name" value="Calcium/calmodulin-dependent protein kinase type I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24347">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 3 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="11"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0012475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="357" mass="40411" checksum="355353278DD740E9" modified="2023-09-13" version="1">MSTPAIVPCKYKTGRVLGEGTYAVVKEAVHIETGKRYAVKVVSKKLMEGKEHMIRNEIAVLRRISVGHANILTLADYFETMNNLYLVTELAEGGELFDRICRKGNYYERDAANLVRTICSAVEYLHEQGIVHRDLKPENLLFKTAAEDSELLIADFGLSKIIDHEKFRLLTTTCGTPGYMAPEIFQKSGHGKPVDMWAIGVITYFLLCGYTPFDRQNSVDEMNAILHAEYHFEPTEYWRNVSDSAKDFVTKLLTVDPNQRMTATEALKHPWLAQVSQSHEMEVDARQQTQIQGGPTDMEGVQQDLLPNMMARMKARSNFRNAVQAVKAVNKLQKLREQLGGHVHPEEVSHVLHHGDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZE3</accession>
    <name>A0A9P6SZE3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">polynucleotide adenylyltransferase</fullName>
            <ecNumber evidence="5">2.7.7.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">PAPD4</name>
        <name evidence="12" type="ORF">BGZ80_011083</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DNA polymerase type-B-like family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.19" evidence="5"/>
    <dbReference type="EMBL" id="JAAAID010000847">
        <property type="protein sequence ID" value="KAG0013433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZE3"/>
    <dbReference type="OrthoDB" id="2274644at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990817">
        <property type="term" value="F:poly(A) RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010605">
        <property type="term" value="P:negative regulation of macromolecule metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031123">
        <property type="term" value="P:RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05402">
        <property type="entry name" value="NT_PAP_TUTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054708">
        <property type="entry name" value="MTPAP-like_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002058">
        <property type="entry name" value="PAP_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12271">
        <property type="entry name" value="POLY A POLYMERASE CID PAP -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12271:SF40">
        <property type="entry name" value="POLY(A) RNA POLYMERASE GLD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22600">
        <property type="entry name" value="MTPAP-like_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03828">
        <property type="entry name" value="PAP_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81631">
        <property type="entry name" value="PAP/OAS1 substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Poly(A) RNA polymerase mitochondrial-like central palm" evidence="11">
        <location>
            <begin position="21"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="PAP-associated" evidence="10">
        <location>
            <begin position="257"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF22600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0013433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="354" mass="39791" checksum="CA2C188305BCE364" modified="2023-09-13" version="1">MIATSAAAVANNSVSPHIQRLTSDMVELAERIAISPEGTQLRENLITRVQGILDTEWPKEAKIECFGSFASGLGTDSSDLDLVILPALHDHEQDLATPGRFQDLFVLKTLFQRYSMKDVEVIQGARVPILKFTDHKTGIKVDINYGQYTGLYNTRMIESYVRIDDRIRTFFYVLKAFVKARGINSPPFGSLSSYCYIMMAISYFQTLLIPVLPSLQDPHLIPHNVPNPGPYGSTRLVNVAFTDPSRIRPCIPRNSMTLGELFVGFLEYYGSKFEYTKSCVSIRCGGVIPRNETPSTWARHAFVVEDPFILDLNVAGARQDMMNVIRHEFQAAVQALRDGRGLSAILTERQPYRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZK0</accession>
    <name>A0A9P6SZK0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Rab-GAP TBC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_011506</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000933">
        <property type="protein sequence ID" value="KAG0012794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZK0"/>
    <dbReference type="OrthoDB" id="159449at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.750:FF:000003">
        <property type="entry name" value="GTPase activating protein (Evi5)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.80:FF:000027">
        <property type="entry name" value="GTPase activating protein (Evi5)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.270:FF:000001">
        <property type="entry name" value="TBC1 domain family member 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.750">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050302">
        <property type="entry name" value="Rab_GAP_TBC_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219">
        <property type="entry name" value="RAB GTPASE-ACTIVATING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219:SF22">
        <property type="entry name" value="RAB-GAP TBC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23436">
        <property type="entry name" value="RabGap-TBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="5">
        <location>
            <begin position="199"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="468"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="590"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="850"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="661"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="468"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="595"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="856"/>
            <end position="873"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0012794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="942" mass="104381" checksum="808A4FDD1A7FDA7E" modified="2023-09-13" version="1">MLDDILDNASSDSLSHGLESSLHSRIGGSSSFLSASNVASRARLNNNTTLGFLLPQPKGHFSKLKGRSELSSDSGVDQELLHKLEEQNSTLPPQDSTSFLLARLERQNGLLDTDPKSVCIESNVLKGNLSTLHRLIADSTTLNSPNSETVDPMSSISSVLEPQAGDEEIDWEFWGMLVQDYNAVASKLPHLLAARVRQGLPSKLRGLIWQSMSQASSTYLETMYTQLLKEHSPYERIIQRDLARTFPQVDMFKEEGGKGQSMLFNILKAYSLYDPHVGYCQGLGFLVGPLLMNMDEKEAFCVFVRLMETYDMRTMFTLNMEGLQLRLYQFSALLSEHLPMLHAHLQFHAIHGAMYASQWFLSLFAYTYPLPLVLRIYDVVFSEGAPETIMRVAVAFLKKNEEKLMQLQEFEDLLEVLSSKLYDVYEDNAGAVIKDAMALSSEISKDKLDALAMAYLAELEDQQKRAGEVTSKRFKDRFRGKTEEAKPEEAKPATNQKKPSSKMNRLSIAASFVSSSSFALNGSGSDDDEVAKSNNSDAMLLEQIQDLAKALSTLQRDHVEVTEAVVTAKMEKMQHLEEIENLRKKVTELERQKNRSSVMSAVSPEMSQSDGASSIMSPRTTIHEDGKSGCASPSWSTLSRDDETTCADTKASSISSFNGSHEELVQRLAATERELAHVTAELVNAKVTVMEAMNEAESERQKAQTIEKVLMDSKEAVVLLQDQQIVLQNAKMAMAMEMDTLRHERDDFERDLNVTRQQFEETKKLWLEGQVERHSLQEKVKELEMNAAFAASSANLGRGRSFRKSLGETAVMTLMSSRSGSPSPRSSTQFAAEVDGISHRGSVEDIRGLARRDSSDTLGSTKSGRDSVSSNRPVNLVRKGWPSEKAASAGVVPTSPTNSSFGTRKFVAAPADAEASKLKRSQSTRNSMFGGLGFRRTASETS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1N9</accession>
    <name>A0A9P6T1N9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007536</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000388">
        <property type="protein sequence ID" value="KAG0018117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1N9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="64"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0018117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="107" mass="11380" checksum="81490AC24844E510" modified="2023-09-13" version="1">MTTVRGSRAQPQSLAQRLSKASMAGRHDAAHSESESEDQDRTPRAQHQTIGVKTSSETLRAKKLANASNASTPNTTASNTLSTVSSSTAVSNSKPNAEKKFLNIIQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2N9</accession>
    <name>A0A9P6T2N9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mitotic checkpoint regulator, MAD2B-interacting-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004604</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000233">
        <property type="protein sequence ID" value="KAG0020204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2N9"/>
    <dbReference type="OrthoDB" id="206969at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018800">
        <property type="entry name" value="PRCC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13621">
        <property type="entry name" value="PROLINE-RICH PROTEIN PRCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13621:SF2">
        <property type="entry name" value="PROLINE-RICH PROTEIN PRCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10253">
        <property type="entry name" value="PRCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="67"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="135"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="167"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0020204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="423" mass="44748" checksum="DC9926843CB4F804" modified="2023-09-13" version="1">MNALAAYGSDSEDSGPESTPVSTTPRAQAPGAVSTSKSGGDSKITSLSSMLPPPKSQSSTSGGISNTSATKKASSTPTASISSIPKTSIYHTLPTLGPDSDSEEEESEFRKKAKLAEAAKNAGSGVSALFAMLPAPKSSTSSSSSSASGSGKPASAKPNFMPRTVKKPTPVVKKPIVAAADEEKEDDDDEDEEPVSFFPLGSAVTAVPKSSAAGKTASNSYIPLFFDKKPLTTEEQQAQNQESVDVSITNEQYAYPTNDQYAYNEQYAYATNDQYAYQTSDQYAYQTNDAYAAYGTDAYAHQGYGSQPESASSSTNTMAIDDAGLQKLGMRKAKDVPINIIDVSARDQMRHAQHARLSMAGSGSQAKPVDLGSIEHLKPTTGQKRKHNIMSLAYQAKANQQQLNASWAASRQTKAETQSKYGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2Y3</accession>
    <name>A0A9P6T2Y3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000244">
        <property type="protein sequence ID" value="KAG0020038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2Y3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="299"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="106"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="315"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="359"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="388"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="399"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="425"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="470"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="485"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="501"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0020038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="613" mass="65693" checksum="1E2A8499CC065E29" modified="2023-09-13" version="1">MSSSGEKDSGSKTGASKEMLDLYDGTDDLLDYGDTYDLDTELLDIDLAEGEEFDLGPEDDLLLNAPETSAKSDGTEGKDAGDSESAQNGDATNVDVPEYANECTDDPTQSTSTSSDVNDNNTQVGKRNDQSVQNQPNQGQRDGNFGGYNRQLNNGRPPYSASSPRGGHGRGGPGGMRGRGQGYMGMGRGNFQGGAGMGHHSMMGMNMGMNMGMGVNGMGVNPAMAQGMNLGVNMNMNMGMMGMAGAHFPGDGYGNQGMGYPYGRGSGMDANRMNPDVGGMNVRGPGVVGQGRTIHINPKFQNRVGIPPIAGQGIPSSDRSQYPQQQQQQQQYQQQQRSQSQDSSRGQSRAWESKSSSLPRDDRNDRNDRNDDRYEQRHSGRDDRGSNYDRSNNLASSRSPDRGTRDSGDSYRPLARSDRDERSASARSSSDRTAQSDMRRGSPSQQQSSLGARGRSPHGGGITSRLGLKRSGEGLDDSYKAHKSSGVSTPRGEQTRASNTTDKDTESVSFLRDKRGPTEFSRDASMGSNRGGGDANPKGFVKMENVPESLSDASIRKLADGISGVDRVLTISKKGDRIVTLGFASVDEAKFFRRQINRTTIEGSLVTVTLASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T321</accession>
    <name>A0A9P6T321_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">SNF1</name>
        <name evidence="17" type="ORF">BGZ80_002709</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="JAAAID010000168">
        <property type="protein sequence ID" value="KAG0021288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T321"/>
    <dbReference type="OrthoDB" id="193931at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12122">
        <property type="entry name" value="AMPKA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14079">
        <property type="entry name" value="STKc_AMPK_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14334">
        <property type="entry name" value="UBA_SNF1_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000544">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000236">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.80">
        <property type="entry name" value="Kinase associated domain 1, KA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032270">
        <property type="entry name" value="AMPK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028375">
        <property type="entry name" value="KA1/Ssp2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013896">
        <property type="entry name" value="SNF1_UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF110">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16579">
        <property type="entry name" value="AdenylateSensor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08587">
        <property type="entry name" value="UBA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103243">
        <property type="entry name" value="KA1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7 17" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="15">
        <location>
            <begin position="10"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="16">
        <location>
            <begin position="289"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="386"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="519"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="746"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="408"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="473"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="531"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0021288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="870" mass="95894" checksum="9BDD84C50A4173EB" modified="2023-09-13" version="1">MTSNIKIGPYMLLDTLGVGSFGKVKRAVHSLTGHTVAIKIINKNKVVNQDMFARVKREIQYLKLLRHPHIIKLYEVISTPTSIYMVIEYAGGELFNYIVDNTRLSEDEARRFFQQIVCAIEYCHRHKIVHRDLKPENLLLDPSMNVKIADFGLSNIMTDGDFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYVMLCGRLPFDDDYIPLLFKKINGKSISMRGIYSLPSFLSPETKYLLTSMLVVDPLKRITIAEIRQNAWFNVGLPEYLKPLPQGVTDDIFCNLQEDIITELMKKMNFSRETIIQALEERQNNQIKVAYQLVVDHRRMIENGEPKYIYSYMKSHRKFKLSEAYLPFGLTTNFVDYGNALITTASSMSPQKPFQSFLATSPPPWNDAEKDGSPAKSAMGSSAGSALKSGLEGDISDDSADSPVPSSITVLSTSLPGNSFAKELHRKASMKNTRRERPTSLQSHPQSSNQNGQQLRQPVSPPFGHPDYSTTTSFHQAAVLGNSSLGGGGIPLPSRTGGPSYTSSSNSNPGAAPTAASAVQRRMKARPKWYFGIRSRSAPKEVMAEIYRALSNLSMKWKIINAYHLRAKYEYAVGFEVKIELQLYRLDNENYLVDFKYVGQQSASALEARAEMMKNLNEESLMETRFGGKSLQLSSSNATMDNANKISSSASEITPSVTSVTESYPTTAMAQGAAHIMSGPQDIPQSGYSVDQSDPAIPSPLPKHHAVAFETNTDQDPHSAGGERSSKRLSMLSSMSLPSTSSATVGGTGVGVGAGASAPGVLSSSLLQEQQHIKEMNELRQELQHQQRQRDLKQRPTHLLFPKASYQLASAKEVNSPFPFFDVCGKLITELAIGSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3Z6</accession>
    <name>A0A9P6T3Z6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000128">
        <property type="protein sequence ID" value="KAG0022011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3Z6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="238"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="306"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="282"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="306"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="341"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0022011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="350" mass="38085" checksum="0801C3006569C0D2" modified="2023-09-13" version="1">MNSTLTVQPNDNDATGATRRRSATLTDPFSVRIEEDMQSTGRQTPDAAPAYSATSPLGPLSPAIVDAISSASIEYRQSLAMSILSSTQSLSYHPDSPSIGVRAGTAQSSVVSSIDEFAPIHLLGSSPRSSVTSDWPLEDAGETEVTEASSSTGVSNDPNGLLARPIEPNPPTYDPAWRSSLPLSQRLHTRDRIRSIQSYSDQTSPRLFVGREASQSLELHQGSRRGQLPGQISRLMQDQEPGQHHNRNEHLHASTSHRRTESFNSSRGVQGRRPPAHRRGLTMNTNLSTSRRTLSWTGNMIAFNPSRSRTSSHASHDLPSQRTHLFSSWSPPPETTVPVNHGRDSASEEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T4H3</accession>
    <name>A0A9P6T4H3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Large ribosomal subunit protein mL67</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_010465</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mL67 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000073">
        <property type="protein sequence ID" value="KAG0023085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T4H3"/>
    <dbReference type="OrthoDB" id="434092at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000150">
        <property type="term" value="F:DNA strand exchange activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024629">
        <property type="entry name" value="Ribosomal_mL67"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28184:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML67"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28184">
        <property type="entry name" value="MITOCHONDRIAL HOMOLOGOUS RECOMBINATION PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12829">
        <property type="entry name" value="Mhr1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00035185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0023085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="186" mass="21030" checksum="9765B6FBE716C1EB" modified="2023-09-13" version="1">MSTASVAGAAKSVATKSSPSKTVYLFRNIQTSQVLVSLKNTVEKQSLKQITDETRRPAHVRHDHWHPLVAIQGFPRHQDALAFHNSLRDHQLNLHATKIADEKHMLQPRRLRAPQEMNQVDGTLIKMVELLNEQPQIKANKGEGIQILWEREGIRKQILEKDGITLPEGIKHGDLSIKRGRDIVNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MC45</accession>
    <name>A0A9P6MC45_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008973</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010005062">
        <property type="protein sequence ID" value="KAF9991673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MC45"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9991673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="116" mass="13208" checksum="49B71BFC51029A2D" modified="2023-09-13" version="1" fragment="single">DVHCTAEFRRLAQDLGWNDKALCSHYYKGLKESVQDILAQRKYRDLDFDSLANDSIEIDNLQYARALEKKENQRAGPVPPQTRRSNPSPSNPRLLFPTPNVSPNPPSTLEPMDLSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MCK8</accession>
    <name>A0A9P6MCK8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">phosphoserine phosphatase</fullName>
            <ecNumber evidence="4">3.1.3.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">O-phosphoserine phosphohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_008575</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glycerate: step 3/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the HAD-like hydrolase superfamily. SerB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.3" evidence="4"/>
    <dbReference type="EMBL" id="JAAAID010004691">
        <property type="protein sequence ID" value="KAF9992384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MCK8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036424">
        <property type="term" value="F:L-phosphoserine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006564">
        <property type="term" value="P:L-serine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050582">
        <property type="entry name" value="HAD-like_SerB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004469">
        <property type="entry name" value="PSP"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01488">
        <property type="entry name" value="HAD-SF-IB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00338">
        <property type="entry name" value="serB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43344">
        <property type="entry name" value="PHOSPHOSERINE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43344:SF2">
        <property type="entry name" value="PHOSPHOSERINE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0718">Serine biosynthesis</keyword>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9992384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="189" mass="20722" checksum="90C2CBEF635B0BF6" modified="2023-09-13" version="1" fragment="single">EITEAAMNGEIDFKESLRRRVALLKGTPVAVLDTVREQLTFTEDALYLCKALKKIGFKLAVISGGFMPLALHVKNILGLDYAFANQLKVSPDGLYLTGETVGPIVTGERKAELLEVIAQAESVTLDQVIAVGDGANDLWMLAKAGLGIAFNAKPRVQQKARTRINQKSLKYVLYLLGYEDAEIRQLENS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MDN5</accession>
    <name>A0A9P6MDN5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Serine hydroxymethyltransferase, cytosolic</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">SHM2</name>
        <name evidence="7" type="ORF">BGZ80_008083</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SHMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004288">
        <property type="protein sequence ID" value="KAF9993590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MDN5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004372">
        <property type="term" value="F:glycine hydroxymethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019264">
        <property type="term" value="P:glycine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046653">
        <property type="term" value="P:tetrahydrofolate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049943">
        <property type="entry name" value="Ser_HO-MeTrfase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019798">
        <property type="entry name" value="Ser_HO-MeTrfase_PLP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039429">
        <property type="entry name" value="SHMT-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11680">
        <property type="entry name" value="SERINE HYDROXYMETHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11680:SF35">
        <property type="entry name" value="SERINE HYDROXYMETHYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00464">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00096">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Serine hydroxymethyltransferase-like" evidence="6">
        <location>
            <begin position="1"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9993590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="312" mass="34179" checksum="83031849FBBD92C9" modified="2023-09-13" version="1" fragment="single">SMPYQVDSTTGLIDLDRLEENAKLFRPRVLICGASAYPREWDYARFRKIADQHGAYLMCDMAHISGLIAGQEAESPFKYCDVVTTTTHKTLRGPRAGLIFFRKNKDAKVEKGEDLESRVNQAVFPSIQGGPHNNTIAGIAVALKQAASPEFKLYAKQVIANSRALAATLVKHGYKIVTDGSDNHLILWDLRPNKLTGSKVERICDMVSITLNKNSVCGDVSAVTPGGVRLGASALTSRSFKEADFVQVGEFLHRTVQIALAVQAKAGSKLMKDFVAALEGNQEIAQLRKEVEAFATSFPFPGFDVKDLKPNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MEC6</accession>
    <name>A0A9P6MEC6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007524</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003874">
        <property type="protein sequence ID" value="KAF9995391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MEC6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9995391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="62" mass="6750" checksum="A27179EEFF604624" modified="2023-09-13" version="1" fragment="single">VEEDEDEGMDVEFSASEADADGNADDDEDDSDELSQVPEEGTFLIDLEVRRGKILLCGVLVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MEY1</accession>
    <name>A0A9P6MEY1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Crinkler effector protein N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_007582</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Host cell</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003907">
        <property type="protein sequence ID" value="KAF9995183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MEY1"/>
    <dbReference type="OrthoDB" id="2304312at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043657">
        <property type="term" value="C:host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045379">
        <property type="entry name" value="Crinkler_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20147">
        <property type="entry name" value="Crinkler"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Crinkler effector protein N-terminal" evidence="4">
        <location>
            <begin position="6"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF20147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9995183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="132" mass="14759" checksum="6489CFBC0390254D" modified="2023-09-13" version="1">MTSVKVKLFCIIDGDSTAFSVKIEPEDAIDDLKDAIKKKQSPLFDDIRASELILWSVDVADEGIPVHLDHVESKTQLTKSTKSIKIVFGENPAADTIHCIVRRPAPAFILLKVNTSTFLRRQVVQVHHLLKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MEZ2</accession>
    <name>A0A9P6MEZ2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007213</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003656">
        <property type="protein sequence ID" value="KAF9996561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MEZ2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="135"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9996561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="333" mass="36252" checksum="EA7C51CE5FD75C59" modified="2023-09-13" version="1">MAKTKPRVLSKEETDKIRQQFGDYRADSERQDRHTNVSSERKEKLVYTETDGQHARDHLRDREPPMDATSGSDSDSSTDDDEVNEMRRSASRSGASVSTFTSANLLNRSKTIASTGINSRGPREINRRSATYLDANIGSSSNSNGNSGATYNGGAQSTKDTTLRHHSSSGSLRSVARLGDQRRSVTLRSERKDDSRVVGDMKEEVSDKQELPLAGITTNSKESVPPPSSQPLSQQEQPSHRDLPHSSVTLSHPPAAYKVPTESPASIAMGLLPIATSKTIVDEEGGDWGLQAQPRRYNSVKLGMTGVTGVTRRAIGRPIERGHGVERGPEDCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MG19</accession>
    <name>A0A9P6MG19_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_006908</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003444">
        <property type="protein sequence ID" value="KAF9997890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MG19"/>
    <dbReference type="OrthoDB" id="2393615at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9997890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="282" mass="31917" checksum="5FB3BC29ED1E003D" modified="2023-09-13" version="1">MAELKLRNLPLQDRDIAEVIEGIQPGLATISFNQSRFGPLAFEPLLRQHAASLTGIYLGSKTFTVTSAMVQKILTTCHQLMRFGADMLNVRDILGIADIDAEDSEDVDEEGGGKNKGRDWVCTKLTLFEVFICGLKDKPLSWHKGVFKQLSRLECLEELYVGACTEFKENTQRSVFQNETICDGLDMRLEAGLGSLSSLKQLVGVGFSYMKQELDEEDVRWMVASWPNLMAVFGELNTERSKSVRLAAILEERGIRTTVDELDSDVEEQDFDLFEMFQVYWY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MGA7</accession>
    <name>A0A9P6MGA7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Armadillo repeat-containing protein 8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_006860</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003415">
        <property type="protein sequence ID" value="KAF9998102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MGA7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034657">
        <property type="term" value="C:GID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038739">
        <property type="entry name" value="ARMC8/Vid28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15651">
        <property type="entry name" value="ARMADILLO REPEAT-CONTAINING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15651:SF7">
        <property type="entry name" value="ARMADILLO REPEAT-CONTAINING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00514">
        <property type="entry name" value="Arm"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00185">
        <property type="entry name" value="ARM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9998102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="350" mass="38516" checksum="4D4CF847BC27383A" modified="2023-09-13" version="1" fragment="single">MTLTPHEVAVSQLDPTQTVPLDRIKSLRFIKNNIIGNKTKKDLYIQLGIVSRLRDIISARDEKDPQLKTQATIVLGSFAFGNENNILSLTDSGVVEPLLSCLNPNGDPKLIEAAARTLNAIYASPKVSRRELFMGDHLNILVQLLDTYSSSYQLGQGVVMLHTAELVASILARCCETTDQQMQIAASGAIPLLMRLLTSGVSKSQEASLGALAALVKDNSELARLIAHMRLEKGERPAPYILRLVWDKSPTMRLAAATCLTYMNRAGVIPEHNNEIMSTVLPILVKMLQLSGYVQETAPKVLAHLIWESENMQKAVCDMDAIPRLASIISQMDEDDNVYGIVGQKDKLKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MIL3</accession>
    <name>A0A9P6MIL3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Ccch zinc finger and rrm domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BGZ80_005782</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">May be involved in the turnover of nuclear polyadenylated (pA+) RNA.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002842">
        <property type="protein sequence ID" value="KAG0003545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MIL3"/>
    <dbReference type="OrthoDB" id="443401at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12257">
        <property type="entry name" value="RRM1_RBM26_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22249">
        <property type="entry name" value="UDM1_RNF168_RNF169-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1390.10">
        <property type="entry name" value="PWI domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002483">
        <property type="entry name" value="PWI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045137">
        <property type="entry name" value="RBM26/27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14398">
        <property type="entry name" value="RNA RECOGNITION RRM/RNP DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14398:SF0">
        <property type="entry name" value="ZINC FINGER PROTEIN SWM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01480">
        <property type="entry name" value="PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="11">
        <location>
            <begin position="300"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="10">
        <location>
            <begin position="467"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="10">
        <location>
            <begin position="803"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="7">
        <location>
            <begin position="300"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="86"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="394"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="543"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="677"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="762"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="849"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="605"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="135"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="200"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="211"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="253"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="282"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="408"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="677"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="687"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="715"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="853"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="874"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="900"/>
            <end position="911"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00043866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0003545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="926" mass="100351" checksum="9DD91873AD1E690C" modified="2023-09-13" version="1">MHIDDTTLDDLKAYLTKELTLISDADPGMLADYIIALLKHDKENNELKTLCVSQLEDFLLEETEPFVTSLFKVLDSKSYIQGKAAVPKSSAPAAAPAPASGSTSASTKVDNDDFDDIPTGPAADRKYESSSTRVQSEKHSRGDSDGSDNEDRSYKHARRDDDRSNDRRRRDYSPSRPSDDDRFGGRRGRSNDFGGSNGHSDLDRRGDRGLRQQGLTTAGFNNRNNNNNNQNNPNNFNGMNNNNNGMDRPHWNGPQQNRNNFDNGPRGNFQDQNQGSWRGGHNMRGGRGGMHGGPGFGQDRQRRQRCRDYDEKGYCMRGDMCPYDHGEDRIVVDEVPNVPFEMMGVVPGMGPNGMMGMGANRPPFFPGGPNGGMMPNPSDIYDPEAASLGVDEMGRSQQGGESFEGRGQHGSGSDGGRFGQDGSARGGMRGRGSLRGMRGGRGRGGSSHPYAVPGRFSGASGSGGTKTSLVVEHIPDEYNTIDKVNEFFKQFGSLTNIQVDQPAHKALIQYSNRDEASAAYNSPEVIFGNRFVKVYWQPDDLDAATFGRQPKPTGQVRPEKPPGAGAHGGPHPHHAPPKPPAASVLMTPERAAELAAERAASAAKLEENKKTMQEIQRQREALIQRQQEEQRLLMQKLFANKSMSQEDKDEILKGLKKVAIEVTKEPLDPLEKARTAAAAAEAQRQAELQKEAEKRERERLDRELEVLNTNPVENSGATAPAAGASTDAADTTAALKARLATLQAQAAALGLESQGGYAGRGRGGFVPRGRGRGALPNTWTRGGARGGAVVSQHRTFRIDNRSTKLSVSNIEESSKDGLKEHFESFGELESFSMGPDGVSATVQYKTRKDAETAMQQGSQAPNATTPLKLGWISEPQSTPAAGSFATSLPPKTTAPAGTGDITSVATETTVGYESEEDEDGERSWKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MIW7</accession>
    <name>A0A9P6MIW7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Crinkler effector protein N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_005724</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Host cell</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002811">
        <property type="protein sequence ID" value="KAG0003899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MIW7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043657">
        <property type="term" value="C:host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045379">
        <property type="entry name" value="Crinkler_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20147">
        <property type="entry name" value="Crinkler"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Crinkler effector protein N-terminal" evidence="5">
        <location>
            <begin position="6"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="119"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="132"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="553"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF20147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0003899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="553" mass="63385" checksum="7BEF2C2FBD90D7B5" modified="2023-09-13" version="1" fragment="single">MANNPLNLLCLVNDKPRSDAFEVEIESTRSVSALKDLIKTEKAKDLRDVDAEKLTLWRASISSENPASTTMIDALDDKIELNNPSTHLSTFFPESPDDNTYIIVQQPPHVPEDISTLCSGHAWSGSRPRPASKRDFDGDADDRDAKRSRSYIQTKGVVSWRSPSLMLPFPERSFFREVHRVEAAILDALSRSWSYQVFHQELSWEDLTVMLRELRPSPRHYFLVDDFQSVFRSSIFPRVAKKFFRNLSSMNAVSCVIVGTFKRTDLLLDDGPMESLFNKANFARMPPFDPREMSRLFDLYKEHCYSDISRQIQVKIAHESGGHPTSFMALPKLTLWHHPDESSYASMLQKNIRPLLEETQTKLKMNLKSMNTEQNARVRDLTNNQMNDWEFIPDDFDRYLLNVGILDSHNDRTVRFTSVIILHICIDVLRPQPENRLSREEIGDPINLLKLGLQCISPSTVAHPLVQNKFGSQESSFHMALFSASYHDKVFVRSKGEGQSDFKDYLEQASKRADSYGIPVYLVNFYQEGRSTPARLFHIPANVAMVNVMRNKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MM13</accession>
    <name>A0A9P6MM13_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_004951</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002474">
        <property type="protein sequence ID" value="KAG0007201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MM13"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0007201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="181" mass="20382" checksum="E0F05B75DF79CA4A" modified="2023-09-13" version="1">MKKFDITDKATANESYSSLIKSPCINKTQQKLQNAYELFLKRFEKKIWERRAVIAQNASVKELSSGFERYRLDSKTIEYSDYKIIDDRDTESETDNRSDAGTKIIFAGPSVSDDSLAANAVPLANDSGSVIVLTINCRLVISEMNKKIMTLDRDLEVALDQWAASFKGNIKEAELIASQQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MM44</accession>
    <name>A0A9P6MM44_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GST N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004413</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002253">
        <property type="protein sequence ID" value="KAG0007641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MM44"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00299">
        <property type="entry name" value="GST_C_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00570">
        <property type="entry name" value="GST_N_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.110">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058268">
        <property type="entry name" value="DUF7962"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25907">
        <property type="entry name" value="DUF7962"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13417">
        <property type="entry name" value="GST_N_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="4"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0007641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="352" mass="39712" checksum="AD406BCE626C9D95" modified="2023-09-13" version="1">MSKPVVILHHYQGSPYAEKVIAALRVKGIPWYSVSTSPMMPRPLLEPLAHGYRRIPVMQIGNNIYCDTALILDELERRYPEDNVSLPSYSGAGAAISEMIATWVDVSSFFHTLKTPEEQKLSPLHAVFGNKEFLADRSQLSGGRPINTEAIKRAQPLLLDQLISNLDTLEHALQGPMQALQQNRFPRPEGGWILGTVLPSAADFSAYAIVWWLISTKRAPDYVTPHAYPCIFEWYNQMNDCIKRHKHPTQDRVKISGEEALQVARQESKNMNRGFVPTNDGVHHQEKRKVGEFVAVMPNDYGKIPVKGEILEITHRRVTILPEPLESHQDIDVIIHFPRSGYMIVPAVKASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMN7</accession>
    <name>A0A9P6MMN7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004715</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002376">
        <property type="protein sequence ID" value="KAG0007385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMN7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="852"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0007385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="919" mass="103863" checksum="880D71A5016952F7" modified="2023-09-13" version="1" fragment="single">RLHFGYYGDKSTISESAVRYLTARARLQFGYFAIRGRAFWNVSSEDLGLQCGGFQGLESHEQEEWDGKTGVQDQHRRQRPHHHQHQQQHQQEPRHQQGQSQGQANDSDPSANKDEDPFSRLRGRPNSDAKSRESDREEQRKKIIKGNKKCEEREEKLLLMEAVQYIQRSQPDMIHVFMQQLNPAETNSSSSTDPSTVSERQAAATYWTRVALTKLIDVQPDPDDMVSVPSSPFLNRRTDALWMEYLEQPPKAILKLKDLARHTRPHGGMGMVQDDSRLFQIASGIFNDLATHPRKARKPAPTIIDGPFSYSFDVIRELVVEYGFMPLPEDDTDRKMNFSGGIRAATGEAEIFPSDGSHVAKPGQKGEGTSIWYFYEPQRVEVMVGYLMHKAPEVLDLLFQQGFELFVQPHPGHAGLSRALLLQCCMPGCHAMVRHVYQVPSGKSIGTMAQTQVVGTVKNELMGYGNKPKRIEFQQQDFADVLKGLAPVNVETAVPIMLDLGMERTVVQNRLMELLQIPGSLAPIDIESSTLTVLFQNCIPKTGLSTPRRLKSASEVVNLAIQLSFEIQMEPSEAIDLEWKCSFEETLLNLEQENLIVHNHVSDWILASLDPSHAGFRICFDHAVLKALLGVTEWNMAQLMRLRTWTRIQEREARTKNDKARCQWEEVKRQLLIVEHENLDDQDVVMQDQADNRNLIELDIEWTTNDEVTLATSTKVDSLPKGSGTIRVGDDGCLLLDNGHLERNQILFDPENGDPNVLDTNTRVYEFLRKGVVVEERHWVWLAMGLDTISLQGQHVVEMAGYEKLSDGGYIFPVKMACSPEAYQLVWMMALAYVQQSLALDDKDSKVELRCRNGDPSPPLPDGRATSPIPLTPSSPVPQSACSFKIREVQRMLTDRLGEEAGLVVKILSELEVDLEKQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMN9</accession>
    <name>A0A9P6MMN9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004164</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002150">
        <property type="protein sequence ID" value="KAG0007846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMN9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12242">
        <property type="entry name" value="OS02G0130600 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0007846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="216" mass="24718" checksum="DDD457A51C04A057" modified="2023-09-13" version="1">MTTATVDSPATGLRKFLGYDNLDLSRVVSSNLISAHTLLVIRTVISLHLSAVFIATLYVSARDDVFYMVPTTFTNLTIYWGMLFDPNNTMDTLNQYVDYSHHGVDLACLLLEMVFNRMELPWVCILGPISMVILYMFLAWVYFAARGEWLYSFLDWSKGPIAAAWYIGLLCIFALLFVLQRYIHRGRDYALRRRRAVVAAQDNSKAVEDFKPSEKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMQ9</accession>
    <name>A0A9P6MMQ9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ABC transmembrane type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_004955</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002475">
        <property type="protein sequence ID" value="KAG0007197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMQ9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042626">
        <property type="term" value="F:ATPase-coupled transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF353">
        <property type="entry name" value="ABC TRANSPORTER ATP-BINDING PROTEIN_PERMEASE VMR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040378869" description="ABC transmembrane type-1 domain-containing protein" evidence="6">
        <location>
            <begin position="28"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="84"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="119"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="318"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="253"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0007197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="371" mass="40205" checksum="FD115CFE61E0D123" modified="2023-09-13" version="1">MGIQPVQLLAVAPLAFTLLSGAACTFASRSSNLALNPNATPPSPTQLTGRKSTFNYTLLPNMGASDNTTDSSQPKAKDIKARNFILLFISLIPALFLVVSCVLVVASQNSAERTLFERLFAPASSLAGWVVTLLVLFGAKYEEDRYNKAIEVCALKRDLEIFEDGDQTEIEEKGITLSGGQKQRISLARAIYSRARHCLTGPIMKNRTCILVTRHVRLCIPTAKLVVSMNNGEIKVQGSIQRLREQGSLSLVLDENEDQSTGSSNSDITDETEAGSSTPTGLAHGKSTVKNGQEPVTPEKVAKKLVQEESLEEGHVKLLVYLAYATAVGRVAFWTVFLASYAVARSMDVFKSLGFVSGPIRTKKVRPLPDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMR1</accession>
    <name>A0A9P6MMR1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Peptidase S8/S53 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_004505</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002291">
        <property type="protein sequence ID" value="KAG0007567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMR1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF11">
        <property type="entry name" value="CEREVISIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase S8/S53" evidence="6">
        <location>
            <begin position="3"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0007567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="146" mass="14568" checksum="406F249E1220FE5D" modified="2023-09-13" version="1" fragment="single">SQAIDDAAGRLYAANIPLIVAAGNDETADACDGSPSGAPNTFAVAASDNTDTTAYFTSWGSCVSIFGPGVDITSAWIGSPDGSNTISGTSMATPHVVGVAASYLSQGNFASAQALFDKLTSTATPNKIQGDLKGSPNKLVYNGASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMV3</accession>
    <name>A0A9P6MMV3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">deoxyhypusine synthase</fullName>
            <ecNumber evidence="6">2.5.1.46</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_003776</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[eIF5A protein]-L-lysine + spermidine = [eIF5A protein]-deoxyhypusine + propane-1,3-diamine</text>
            <dbReference type="Rhea" id="RHEA:33299"/>
            <dbReference type="Rhea" id="RHEA-COMP:10143"/>
            <dbReference type="Rhea" id="RHEA-COMP:10144"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57484"/>
            <dbReference type="ChEBI" id="CHEBI:57834"/>
            <dbReference type="ChEBI" id="CHEBI:82657"/>
            <dbReference type="EC" id="2.5.1.46"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Protein modification; eIF5A hypusination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the deoxyhypusine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.46" evidence="6"/>
    <dbReference type="EMBL" id="JAAAID010002013">
        <property type="protein sequence ID" value="KAG0008174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMV3"/>
    <dbReference type="OrthoDB" id="294378at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034038">
        <property type="term" value="F:deoxyhypusine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.910.10:FF:000001">
        <property type="entry name" value="Probable deoxyhypusine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.910.10">
        <property type="entry name" value="Deoxyhypusine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002773">
        <property type="entry name" value="Deoxyhypusine_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036982">
        <property type="entry name" value="Deoxyhypusine_synthase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00321">
        <property type="entry name" value="dhys"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11703">
        <property type="entry name" value="DEOXYHYPUSINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11703:SF0">
        <property type="entry name" value="DEOXYHYPUSINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01916">
        <property type="entry name" value="DS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0386">Hypusine biosynthesis</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00009892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0008174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="374" mass="41267" checksum="4BBBEB404F9C22EB" modified="2023-09-13" version="1">MSPGQEALPDSTQAAVFVASTEMPKDSVVIKGLDFNQTVTLDSLLSTFITSGFQASAIGRAIEIINEMRQWRLSDDPLPVATEQNPVDPELLDPEYRKSIKCKIFLGYTSNLVSSGVREVIRFLVQHKLVDCLVSSAGGIEEDFIKCLAPTYLGEFTLEGAKLRKQGLNRIGNLLVPNDNYCKFEDWVVPILDKMLEEQNGEEKAHWTPSSVIRRLGKEIAHEESIYYWAYKNDIPVFCPALTDGSLGDMIYFHSYRSPGLIIDIVADIRAMNNQAVFAKKTGVIILGGGVVKHHICNANLMRNGADYAVFINTGQEFDGSDAGARPDEAVSWGKIRMDGKSVKVYSDATIAFPLIVSQTFAKGFHTKSEEASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNB8</accession>
    <name>A0A9P6MNB8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003690</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001998">
        <property type="protein sequence ID" value="KAG0008216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNB8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0008216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="260" mass="27756" checksum="DB54945E0CE39F16" modified="2023-09-13" version="1">MRPTNCSIESFMDEIESEHPLHSTSNGRVNSQRSPSQSSFHLQQQAPLMSSRGGSINLLSRDGPSNAGGPSNDGGAGGSDGDAPRQTPTQDISSAMVEASQEIRQLREQQTQEAMTDRVKRLSKTSDSSADKDRFVRSMDFCQPMSRDGAGMGMGVSTGMGSSAVEMDIDSERNAPVPVRASSGSPSPHDDIVRQIAHRVSQKLREAQESGNSTASYHTLLAQEIAKGQLAGVLPSSPAGSRQNSVYISDPEDPVKSMKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MP00</accession>
    <name>A0A9P6MP00_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Mtf2-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_003632</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001976">
        <property type="protein sequence ID" value="KAG0008268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MP00"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043837">
        <property type="entry name" value="Mtf2-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19189">
        <property type="entry name" value="Mtf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mtf2-like C-terminal" evidence="2">
        <location>
            <begin position="932"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="490"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="651"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="909"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="490"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="909"/>
            <end position="918"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0008268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1072" mass="120002" checksum="8BE3165A786A8756" modified="2023-09-13" version="1">MPLILPESASAVNRALALPEIVFEILACLEAQAELCPQLVQTSLRACTLVNRTWFFDANIFLYRAPYIRNGRGSEAKVNALVRTLSSTNRGLYVRSLSRCKVELWEMFPSLENLFDYCPRLSSLALCFRSGEKGHLMEPFESEAFRSLNPIIAQGMAHVQELDMTSVSINSVDKDDTAYVDAALNCLSACARLQKFVTTRADWTNIRTISRHLTDLSISFVAPPDLKTSVALGPSLVNLTSLHLHHAPHALPSHDFSRVLAQYCRSLTKIDVCPEVITSRSLEMMTLHNPGLVSIHLRNCPDAYTAAVLEHPPQNLEFFDMGIVDSQLILRALSLCPKLISTGKSAPRNNNTAEFWQSFLDKARQIQELHVERWSDFYSKDLFFNTVLPKLGPQLVRIWFGWRDLLGCDELERVLTSCDRLQVLRAPVKGNGQNLVRCFKVVAERSRLREVRLFGDNVKFCDDDKRRSRQRQYFGKSQVTRLISTYTPNFQDTLTSRGGTTSNESKDTTPDSSTQLDAAITETATIATEGSTSKEDLVKKFKLKPSVEVGIRARMLEKQRKQAEEKERIAAENESRTGAEKINRLFEKLQLGGKFASAEGSDVTGHEAVPAASKSISNSWKFLFDETELNENNGNEGGVEAEGKETLDRIPGASNLFPSLSEYQTPPSTPEPSSPTPITEMDSELRLPSTDRWKDPKMKGTERGAFKALFSSLFEQKKPEQQETSPGEKMQSLFSNFNRTGLEQTMESAQESESKSSPFDILTGNFSSTAETGAAREDPMQVRRRQLENLSKRAEPIYLEKKPKTSPFKVMENTVGPQDWLSQDPTMPQENTLFNAIRDENKVSIRMRKELEEKLGNVVQVKQFVDDLIAPFVEPQSVFSSNAVKPSSSSLDSLLAHAILAISSTRLEAGDSKTRTEETQATTDPQPLRSLHPYLGHALVEHTRRQGLPVFIRAVRTESYKALLKSRWDAWHDGPGCLEILKEMQRSGALVDSETKAIVKNMDRDLKAHSSTPSSSDLASATSKEQLCQYGWGSEEQAASLVEMLNIISVANEDGDSEYNMKQWAKRAKSNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MP84</accession>
    <name>A0A9P6MP84_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_003141</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001812">
        <property type="protein sequence ID" value="KAG0008713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MP84"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="225"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="10"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="21"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="41"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="65"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="175"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="195"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0008713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="262" mass="28073" checksum="42D0E2109C9D6950" modified="2023-09-13" version="1" fragment="single">EQQEEQREEQQEEQQEEQQEEQQKEPQEKVEVEAEAEEVTVEEKEPEKPKLPGMESSGPTLSHASRPRPAKGRKPPSAPVPNAETSFVSQLEAEVKAAPIVEEKKPEPAAPAPVPEKTAPPPPPKPVKPIFQKFPTPFAGAQPAAVALRPTGRRTVSGNESTGSDSPSASGTASPVFAATAPSAGAPAPVGGVKSLSSRFGQFQGVPTSGGGSTAALELEIAKLRRYMNEELDRVRKELADERESREKLQAEVNQLKAQLQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPA1</accession>
    <name>A0A9P6MPA1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003401</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001899">
        <property type="protein sequence ID" value="KAG0008464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPA1"/>
    <dbReference type="OrthoDB" id="2321175at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13527">
        <property type="entry name" value="Acetyltransf_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="326"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="326"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0008464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="547" mass="61887" checksum="85C181C5BCDBCFF3" modified="2023-09-13" version="1">MTVEEFFPQTSQRKVIDIGNGLIMRWSTKKDTENISLLVEDAFRWLPAGDPFPQDKVPGPNEFMRAAVRRLLSGKSSIASEFDFALVEDTRREEGKNPIVSCVSLQRHEAYYGSTVLTFGMLELIATDTEYRNKGLVRRLLLDMVHPESEARGDVLQFIPGIPNFYRQFGYDYGLYCYPAARIENADIIPPLGKDKSEPYILRQAKLDDIDYLVQMSKPEVLHNNTTIANIYTRRYWQYTVHDAIEDKQHRFDADRETNIITEVESGKPIGFTIASHNIFGPQLEALSLDEGLASHMEVKDSVLRQLFDQARIRQDLKAKAYEAAQEEKRKTEAEPEKTTEVGDGQKKKIDNDDDAKAAPVSNQTKPGPLSYGINLPGRHPLCTLLGSMAKRSPIGYGLYTRIHSYPNFIKAVTPELEKRLADSALAGVTGRLRLNFYRKVEGSSGKGLEIVFEKGKIVDAKEWDSPSPEKALEERMAWKMEDNAPVLYSAGFAPLTFTNLLTGKDSLDDLVRAYGECGVRNDATTLLLNTLFPKSQYQHHFDIFIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPL8</accession>
    <name>A0A9P6MPL8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_002847</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001724">
        <property type="protein sequence ID" value="KAG0008991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPL8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0008991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="295" mass="34002" checksum="A0C344D949008711" modified="2023-09-13" version="1" fragment="single">MIKKKLQPNDEQLQKYIQNVQKSTLPGLFINYNSVRAYLYRERVYASQKHKDVVTSVELWIEQNEGNGGKERNVRADYLIYMLQGPVVKESQLTYHKIRQGLLPIGQSEYETIRKNKAKKPSMDEARGMISEEQLDLNKLIHFYLILRVHNTYNLANNAVPVQAANQGVGRALDQAPDQDAFQDAYQDADQDASQVNLQDATREAIRKDIINAVEPGLRLQLEAHREQKRREAFEECQKELEESWLRLGKVIMRDEKTRSAKRKRTLTYMQSTVEVLKRATLEVAGIDKVGAGRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQ21</accession>
    <name>A0A9P6MQ21_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_002626</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001654">
        <property type="protein sequence ID" value="KAG0009213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQ21"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050562">
        <property type="entry name" value="FAD_mOase_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356:SF2">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356">
        <property type="entry name" value="FAD-DEPENDENT MONOOXYGENASE ASQG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="13"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0009213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="427" mass="47359" checksum="6988804701A9CE44" modified="2023-09-13" version="1">MSDQASANKSVPEVLIIGAGIGGLMLAILLEQISIPYHIYERATEVKPLGSALSFGGHVLPALEQLGIHKELVEVSKSYTDIYFYDANCKKIGTHDVLAVRDATGYDILIFSRPRFYELLQKRVPVHKISFNKKIVRTEEKEGKVHIYCSDDTSYSGDVLIGADGAHSGVRKSLYEQLDEQGILPKSDLEAFSVGHTAIVGVATSTPEKYPQLKEEDANFSQILYEGSGNCYVITLPNNQISWGFGIQLSNASLRETHLSNAEWGPEANDNTLKDFRDFPCPLGGTMGDIFDATPKHLISKVLLEEKVFTTWHHGRTVLLGDACHKFHPSGGQGAANAIHDAIALANCLYNMTDSSLQSINTAFKEYYAQRHDRVEEVFKRSHFMSKLLNGQNSEYRPQVAWLPLIENRGNGTTLPQEGRRYDTPAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQ29</accession>
    <name>A0A9P6MQ29_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001987</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001477">
        <property type="protein sequence ID" value="KAG0009856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQ29"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="204"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="330"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="380"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="544"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="869"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="233"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="385"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="398"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="423"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="544"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="575"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="609"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="652"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="887"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="915"/>
            <end position="928"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0009856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="984" mass="106328" checksum="B8DC5505747AD531" modified="2023-09-13" version="1">MQQPHNSHPTAHHGGADDGEAEDDLNFHDYIHAKHDDEKDGDESRSAFSSPRPVHSSAIAPNRHNNSATNSLQSQEVDNTVNQNRTHQNQQQVPSHHMDSPMHSSDLGQLYESTSHHYPPPDLVPPPTQDLFRTLMEELQAQAAIQRDQFLASTTRPDSTADTSDFSINNHHARSLPRFMMEPLDFLSANYESCLEPGIGAHAESNGNSSGNSCQESFDSMSQRGFSSSTTISMAPPSTLAPSSSSVSATSNMQSESILTTGPTGISSSKKRQMEDDSHMFGSNNGTTPPTISGSHEELSPPTQDLFRMLMEELETQAALQRDQALASTARSEVTGGAGMSSADFSFGNGNQQIQQHQQHHHHTRLPKFVMDPFDFLSPDYGSMQVDSHPNQHQQTEQPRHDVFMDSGSSEDRQDKSSSSNSVTLQTSGPSMLSSNQQSFSPPKQDLFKMLMEELETQAAFQRDKVLAETTGAATRVDPEEYVFNGQHLRPLPRFMFEPLDFLSSSYDSCFGGDMQGGDGSGSHQFVQPSLIGLDAMRTPTTAGNFAPQDDSSIQISRRGSQTNKYKTILPQRSKPLTTSTGGWTQVNGAGAGTTDSANPLKKRKLGTEEGTMSSESSSTPSLINRAPSPLGPGAREGQDFPISPPSMSELSISPANGAASAPSPEGSTEGAGAAAKRPWTPEDEALLLKLFAKRTPIKEIAQTLDRTVHSIRSRRQILTDPGFVKGKGHGVSRRCKQDPATSTKLPTYAQMAFLSLAWLPDLEGTLNDVATMVEKLFSRHLNRIPRTGHKNLQIWRAQISDALAHEKGQPRPRFESFGLKRGRQWVYRLTDFGKGIVEAMGGVDGICQDLLRCNELELAAAAASASSLGEDSSFGPGAVSRDSDGLIGGTGADAGIGKGEGYGYSYRPPDARKKPGKRSRISKKSIAQKKEEELNRAENQNDGSGGAANAIANAMEAMAAGLAKMMALEDEKAVMTAANAGNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQM9</accession>
    <name>A0A9P6MQM9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_002294</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001560">
        <property type="protein sequence ID" value="KAG0009538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQM9"/>
    <dbReference type="OrthoDB" id="2407602at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0009538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="207" mass="21515" checksum="1ECCAD15EFBB0D86" modified="2023-09-13" version="1">MASKISNTVKEAIGATKEKIGLATHSERLAESGAAENAQAHANKEARSGHAQGMDPNLNPNIRDTNQNVGQDPNYGRTQGMTGGMTGGAQQTSQNMPGHVNDPSLRARGDTNQNVGHDPNYGHTQGMTGGMTGGAQQTSQNMPGNVTNDPSLGARGYAGQNVGGATNDPSLRARGDTTQNVGGDINDPSLRARGNMDPAMREAQRNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQX3</accession>
    <name>A0A9P6MQX3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_002096</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001507">
        <property type="protein sequence ID" value="KAG0009753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQX3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0009753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="283" mass="31593" checksum="6C5C0DB61B38AC3B" modified="2023-09-13" version="1">MPKLSQENLEKHAHFLQAIWFDPVSEYLDKLVHCDQFEPFNRIDIAETETETENALPCEFMKPEPPTSTRESRRSFRRNRKHQNVTPLQVPVAESQLVYQPALHDTITLGITTMAITPAGQVPTIKNEEIKHEVISGANTNLRPGNRNRESKRNKKQPTNIESMQAAVKAVDASAEISPVNKTAANARRRKSKSDKQKERSHKGQDHPLRENGNGIPDRPAAVPIGGQEAKPLIIKPAHNPKIPHDSHEVSASGGNNGSVKKSRGYSRRFPKPGITKQSPDLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRA7</accession>
    <name>A0A9P6MRA7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001316">
        <property type="protein sequence ID" value="KAG0010530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRA7"/>
    <dbReference type="OrthoDB" id="2432222at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38926:SF5">
        <property type="entry name" value="F-BOX AND LEUCINE-RICH REPEAT PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38926">
        <property type="entry name" value="F-BOX DOMAIN CONTAINING PROTEIN, EXPRESSED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="10"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0010530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="478" mass="54719" checksum="0A34B83E6342ECD4" modified="2023-09-13" version="1">MAVVSPLDLPEIRLRIGDYLSKPDLAQCICVCKVWNESYLPFLWKEISVTSDSVFERLRTLTPEVIRSHRELVQVLSIVDMYPGKYKANYPRLNSLTLGANLPPARERISEGDPTELIKQNPSLTHLTLTHLNVYLLANFWKEVSNLPRLQSLKLSLTSIDDESHIRVFWSACTNLEVLSLMHFNFAANIGVDSRLAFPKLRSLTLDLVKNFDQMKQLYFIRQCPQLKELVWHMECPGHGHTLLAEDIGRNLWPHLDTLSLGCNISDEALDPIIKGMARIRKLDLLRCRLGTLSFQSLRHHFSTLAKLILWECPVVTSIMLREVLCSCPLLEELKGGYILARDAVDGGPWICRSMKTIHICFIFRSDEQDLQPLIFERLSHFVQLRNLGLGGWVSPVTKGFQETLDFRLESGLGQLVTMKNINHLSLYRTTQALSEEDVRWISSNWRQLEVVSGKLNHRMAICDALENILRERGVRVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRS0</accession>
    <name>A0A9P6MRS0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001384</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001310">
        <property type="protein sequence ID" value="KAG0010563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRS0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="320"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="68"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="320"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0010563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="404" mass="43038" checksum="488020E3C7CDF416" modified="2023-09-13" version="1">MSFTSSNSSSDSIANPQPLRLSSSSKPKSLSEELSSALQSNGSDTSIGNNKAMAYPSPITPSDLLGIPDPSTFSSTTLTPSDSPVQKADAGRKPRPSLLSINTTLGNSALEDSGFTFPQGSPTSMRDSATNSECPGSPRGLGRHGIPQLEEHEGELSSLSPPEEGQLDNPEREMSMGLGIEVTPSSTTTAVTIVGSTPAFGIHAFREQEDQENNALGLYSAEPPKKRQRSAAAVLLGAAVETVIFTSAVALSAYQLLTGKGKQQLEDATMTPTSDETTAAERTVLEPQSEMSIMPIKSAPVNIPTHAGRHRDSGLLGKSLHHNHHVRPHHKSKHSSKSRHGLSASLPHAYEYDHMKEAMTLPGRPNTGTEDNDEQFLRMEAQLTSLIAEGKRALSSRITDWAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MS98</accession>
    <name>A0A9P6MS98_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">AAA ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">CDC6_1</name>
        <name evidence="8" type="ORF">BGZ80_001012</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CDC6/cdc18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001223">
        <property type="protein sequence ID" value="KAG0011024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MS98"/>
    <dbReference type="OrthoDB" id="1926878at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033314">
        <property type="term" value="P:mitotic DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000547">
        <property type="entry name" value="Cell division control protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049945">
        <property type="entry name" value="AAA_22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015163">
        <property type="entry name" value="Cdc6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054425">
        <property type="entry name" value="Cdc6_ORC1-like_ATPase_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050311">
        <property type="entry name" value="ORC1/CDC6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10763:SF26">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 6 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10763">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13401">
        <property type="entry name" value="AAA_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22606">
        <property type="entry name" value="Cdc6-ORC-like_ATPase_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09079">
        <property type="entry name" value="WHD_Cdc6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01074">
        <property type="entry name" value="Cdc6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="6">
        <location>
            <begin position="290"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="domain" description="Cdc6 C-terminal" evidence="7">
        <location>
            <begin position="631"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="45"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="88"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="123"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0011024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="734" mass="80737" checksum="036BD8020A88D52D" modified="2023-09-13" version="1">MSANFLRKRAIVFSDDEGEDVEAWPASPSKRRSRIIFQKQLLMDKNTIAPPDFGNLDDQSTKDEDEKDTQDETEPAKTHVPKTRTETLKPTATEASLETITPPRTPTRRNTRQHAALSVNIPDVTSMSSTPKKGSGLSTPMTPTKSNNQSTGLTPAMNKLMRSSKENSSPKVAVTTAVKGKKLVKELQDENVIEKEGAKIPGYSTPKRLQRTKSQLGTTDASSAVSCKAVSSGATNNTKVSAASVPTTLGFYQDAKTLFRRTTEPHRLVGRDAERETIRTFCQDHILIPKSGSLYISGQPGTGKTALLKEIMRDMEPEMNNVKHDIKTVTINCMSIKDPKLVYQKLLEEIGYVVESKDKEAVIKTLESLFLESNKKKTLYVVILDEVDQLLTKDQEILYKLFQWSSTEGSNITLFGIANALDMTDRFLPRLKARNCEPQLLNFNPYQVAEIRAIIMDRLFSLEGDGKDGKDGKDDTGKPRVVPLMQRPAIELCARKVAAATGDLRKALDICRQTIEMVELEAKKKERLEKQSQQQRGTNSPLTEIRLANLENQAAGNADRLLLSRRQSSPFTDLSPAGSGTGSSAAATAVTTLQDAPKVTVEHVKKALASAFGSPVVQKMKGLNVHQKIVLVVLVTKIQNGKTADCEVGKVFDHYTSTCRSSNKIGAVNRGEYQDLINMLEANGLITFSKAKEERLRKIGLVPQESEVLEAIKGQDILDTIVSKLSLNVAVAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSS1</accession>
    <name>A0A9P6MSS1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Adenyl-nucleotide exchange factor sse1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">SSE1_1</name>
        <name evidence="7" type="ORF">BGZ80_000644</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001138">
        <property type="protein sequence ID" value="KAG0011490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSS1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd24094">
        <property type="entry name" value="ASKHA_NBD_HSP70_ScSse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.30.30:FF:000002">
        <property type="entry name" value="Heat shock 70 kDa protein 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000171">
        <property type="entry name" value="Heat shock 70 kDa protein 4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000004">
        <property type="entry name" value="Heat shock 70 kDa protein 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.34.10:FF:000011">
        <property type="entry name" value="Heat shock protein hsp88"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45639:SF4">
        <property type="entry name" value="HSC70CB, ISOFORM G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45639">
        <property type="entry name" value="HSC70CB, ISOFORM G-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), C-terminal subdomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="715"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="720"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="737"/>
            <end position="754"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0011490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="754" mass="83958" checksum="7097EE5A35384282" modified="2023-09-13" version="1">MSVVGIDFGNLQSVIAVARNRGIDVICNEVSNRFTPSLVSFGPKQRYLGETAKTQEISNFKNTISSLKRIVGRSFADKEVQEVEKQYLTAPLVEVNGQLAVKVNYQGQETTFTTLQIFAMYLTKMKEIAANETKAPVSDCVIAIPAWFTDVQRRAVLDAAEIAGLNVLRLINDSTAVALGYGITKTDLPEDKPRNICFVDVGHSTYTVSIVSYIKGQLTVKARAFDRHFGGRDFDRMLVDHFAAEFKTKYGIDVKSNGKALIRLMAGCEKLKKILSANSQAPLNIESIMEDRDVASMMKRTEFEELAQELISRVEAPLKQVLEDAGMTAADIDAVEMVGGSIRIPSLKERIQAFFGKELSSTLNQDEATARGAALQCAILSPSFKVREFTVHDITNYPIKMTWQPTPEEEETELVVFNKNNTIPSTKVLTFYRSEPFDLEAQYADPESIPAGINPWIARFSIKKVEPVNGEPACVKVKTRVNIHGVLSVESAYIAEEIVKEETVEASKTEGAEGEEAAAPETRKVKKLVKKCDLPVVSATSSLDRSVIAELKEKEMEMIASDKLVVDVYKDFINPADKEKFVQDLNDAENWLYDEGDEATKSVYAAKLADLHVVGKPVVERYREVDARATAARELRESINQLMSQATSTEEKYDHIPVEEKNSIVEKVSKAQTWIENKEERQSMLKKYEAPAVTSAEIRKQRDDIVYFATPILNKPKPKPVVVETPETPATPAAEKPASEEETKHDDSKDMDID</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSY9</accession>
    <name>A0A9P6MSY9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Insulin-induced protein 2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">INSIG2</name>
        <name evidence="8" type="ORF">BGZ80_011702</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the INSIG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000975">
        <property type="protein sequence ID" value="KAG0012494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSY9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016126">
        <property type="term" value="P:sterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025929">
        <property type="entry name" value="INSIG_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15301">
        <property type="entry name" value="INSULIN-INDUCED GENE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15301:SF3">
        <property type="entry name" value="PROTEIN NSG1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07281">
        <property type="entry name" value="INSIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0012494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="120" mass="13244" checksum="1F5E0C5950B4AE9C" modified="2023-09-13" version="1">MRCMGGFIGVNYAASKLPWTSSLQVSCTLALISAGLWFLFDRTFHGFMISLTVASMGTTVAYFLVLNGWYSFTRADFFGVGSWIPCILYSSSVCFGSIGRQLDVIPKTWFTAGRAHLKSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MT25</accession>
    <name>A0A9P6MT25_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Replication factor A protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_011645</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the replication factor A protein 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000963">
        <property type="protein sequence ID" value="KAG0012584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MT25"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005662">
        <property type="term" value="C:DNA replication factor A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013970">
        <property type="entry name" value="Rfa2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15114:SF1">
        <property type="entry name" value="REPLICATION PROTEIN A 14 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15114">
        <property type="entry name" value="REPLICATION PROTEIN A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08661">
        <property type="entry name" value="Rep_fac-A_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0012584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="85" mass="9303" checksum="2CC53D07B6F2CD83" modified="2023-09-13" version="1" fragment="single">MSLPLTPRVNSAMLSGKVGQTVRFVGKIIEQNGSRALMTASDQGQVEIHMDQNAQYGTQYIEIIGIVNNDHSISEMTSTNFGNNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MT55</accession>
    <name>A0A9P6MT55_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_011698</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000974">
        <property type="protein sequence ID" value="KAG0012497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MT55"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="256"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="256"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="299"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0012497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="332" mass="37959" checksum="9DBE446AB0AA0421" modified="2023-09-13" version="1">MSKGPFTTQFEDTGKFDPEIKTTDQRISMLKERIDELEMVLSEYYLDGAVFREYASERNKLKVARTASIASRATGKTGSESYTGQQNEQSAFQRRWGNTREPLVLPSQTLMESQHQHRGQLPSPQFPPVYARQSQEHTRRQSPEPSALVYYQQQLQKNRQHGKYRSESEQSLLAQLVEDDEEFISPRDAKRYPDQDQQTQGLLQQDHHGMHQTFLEQQERRIQQQQEQPPAFPPRPPKGNIKPIIVNAPLQAPSLLSPSPPLAHASPIDPSDSRSASWRSDGTDRGLKPNTMNSRSIFGSSTYSGHTSTTGTMQYEHVDMSDMSRMVREREL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTD0</accession>
    <name>A0A9P6MTD0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Leucine-rich repeats and WD repeat domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">LRWD1</name>
        <name evidence="3" type="ORF">BGZ80_011611</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000955">
        <property type="protein sequence ID" value="KAG0012637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTD0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005664">
        <property type="term" value="C:nuclear origin of replication recognition complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071169">
        <property type="term" value="P:establishment of protein localization to chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052489">
        <property type="entry name" value="LRWD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056160">
        <property type="entry name" value="WD_LRWD1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24370:SF10">
        <property type="entry name" value="LEUCINE-RICH REPEAT AND WD REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24370">
        <property type="entry name" value="OPTICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23215">
        <property type="entry name" value="WD_LRWD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Leucine-rich repeat and WD repeat-containing protein 1 WD" evidence="2">
        <location>
            <begin position="264"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="321"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="461"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="28"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="51"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="326"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="461"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="479"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="501"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0012637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="622" mass="68366" checksum="98F9B91F1026E3CB" modified="2023-09-13" version="1" fragment="single">MPRRKAATIVESSSDESAPGTERKRVTRASTSSTTRSTRQSTRNEPSISEKSVASNVVVAVRSSKRKAAEEEPKSSVLSVEISEKAKRDTPKHSNKAAPVSSTVKTEAIKSSSKKDLGKNNTNNDSRAKSTGKKNGQKQSSGKRKVDAIGTEDLWLYPNLLDTTNTTVNNSTSMDVDQSHGYFLQYIIRAHSRNTHDGQDEVDNDTWAVAFQPTLPVSRSYDQSHRLGDDGSEKELEDEEINESDHDSDEDSEDSRARKRSRRIAKEESRRKKSSTIVATCGGNTVCLIDCSLGRVMAKYSHVPEEEFMCLAWTTLDHDDDGNDGAESKKEAQAEERHEQSNILAAAGASSDGTARLWDIGSLTNFENEACCLARFVGLDSSSVTAIGVSEKYLIVGTEKGLMAQYNLVELTKEIKAGRKSTYSAKPEKIYPPSPEWHESAVDEIIYIPYFSEESYASKKSTAESAKKRSPKASEKGANRGKPRGGNRRGRGHSNGVKEGAEDEDEVDGSDTEDTYEGEFVFASRESCQGEILVWEATESTESDAKLETILEWPIAESWTKFTLGENMTKTNTPAPGEGKLQQKRQNVLVAGSTDGEIIMFDLGRKPERARDGNIIAEKPSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MU01</accession>
    <name>A0A9P6MU01_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Small-subunit processome Utp12 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_011564</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the WD repeat WDR3/UTP12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000946">
        <property type="protein sequence ID" value="KAG0012704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MU01"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034388">
        <property type="term" value="C:Pwp2p-containing subcomplex of 90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000157">
        <property type="entry name" value="WD repeat domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000178">
        <property type="entry name" value="WD repeat domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007148">
        <property type="entry name" value="SSU_processome_Utp12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051570">
        <property type="entry name" value="TBC1_cilium_biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19853">
        <property type="entry name" value="WD REPEAT CONTAINING PROTEIN 3 WDR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19853:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25173">
        <property type="entry name" value="Beta-prop_WDR3_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25172">
        <property type="entry name" value="Beta-prop_WDR3_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04003">
        <property type="entry name" value="Utp12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117289">
        <property type="entry name" value="Nucleoporin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 6" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="99"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="141"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="193"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="417"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="498"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="595"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="637"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="679"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="domain" description="Small-subunit processome Utp12" evidence="8">
        <location>
            <begin position="827"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="309"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="309"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0012704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="962" mass="108190" checksum="F811840D7A434D50" modified="2023-09-13" version="1">MVKAYQRYTPRTTFGVVASGNSNIIYDADGKYAISPTLEDVSIWDLKKGELVGTWRDSDNKAEVTCIARSVDHDSYAVGYANGSIRIWSMSKSDVLVTFNGHRSAVTALAFDKSGSRLVSGSKDTDLIVWDVEGEVGLYRLRGHKDQITSVRFISRPSIVEGGKPTDGYVLSSSKDTLIKLWDLSTQHCIETLVAHRNEVWSCDVNADETMLVSGGGDPDIKVWKIDAAVLRTGLAVGEEAKEVGEEDADGESSGLVKAITFYGSIPRQSKDRVTTLEFHSSQEFLGCQASDKSIELFRIRSIDEIKKKMSRRKKRQREKQQALLKKGDTAGAAAEEPVDETIQATDEITPWHVIRSGAKFRSFDFAPAKDVQKIGHVQLVASLNNNTVEVWTLPHPTAAKNEEVADEPNKAYTLELPGHRSDIRTVALSSDDELLCSASNNSLKIWNIKTTSCIRTMECGYALCCAFLPGNRHVIVGTKSGHLELFDLGSSSMIESIEAHEGAIWSLQVRPDRRGLVTGSADKDVKFWDFDMIEEQIGQSTKKRLSLVHMRTLKMSDDVLCVRYSPDQKMVAVSLLDATVKVFYHDTLKFFLSLYGHKLPVLSMDISSDSNLLVTCSADKNVKLWGLDFGDCHKSMFAHQESVMAVQFVWNTHYFFTASKDRTVKYWDGDKFENILKLEGHHGEVWALAVGTYGNIVVSASHDRSLRIWQKTEDQVFLEEEREQELDDLYEATLTASFEKTGMVDHGEGNIGAPSTNNGDELASAGKQTMDTLKAGERIMEALELADQEINAWREYNAGVARGERGLSKPQRSPLLISMRQTPEQHVWFELERVRPAELDEALLVLPFAAVTSLLNWLDVFVQREYNINLVCRVLFFLIKSHHNQIVANRIMRPMLDSVRRNLRIGLQKQKDIIGFNVAALNYIRRDYEANNTSEFFDEEAVRKDEEKKQESEKKRKFMKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUE4</accession>
    <name>A0A9P6MUE4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Rho-GAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_011248</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase M3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000882">
        <property type="protein sequence ID" value="KAG0013174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006518">
        <property type="term" value="P:peptide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06455">
        <property type="entry name" value="M3A_TOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00159">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.390.10:FF:000074">
        <property type="entry name" value="Metalloprotease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.40">
        <property type="entry name" value="Endopeptidase. Chain P, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1370.10">
        <property type="entry name" value="Neurolysin, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024077">
        <property type="entry name" value="Neurolysin/TOP_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024080">
        <property type="entry name" value="Neurolysin/TOP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045090">
        <property type="entry name" value="Pept_M3A_M3B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001567">
        <property type="entry name" value="Pept_M3A_M3B_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11804">
        <property type="entry name" value="PROTEASE M3 THIMET OLIGOPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11804:SF84">
        <property type="entry name" value="SACCHAROLYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01432">
        <property type="entry name" value="Peptidase_M3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2 7" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Rho-GAP" evidence="10">
        <location>
            <begin position="186"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="75"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="391"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="461"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="543"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="635"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="8"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="76"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="121"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="399"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="470"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="501"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="543"/>
            <end position="558"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0013174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1298" mass="143679" checksum="F67B0ECD84CC7023" modified="2023-09-13" version="1">MATTEETPSALLPASLPSSASSSPALSSTGRFKPQPINLVYNSHLELPQSSPKRGSIAAHLMSFAAKSTTSLHILSSSAPTQSSSSTPPSSQDGTQSQVPAHRTTGFSNPFKKFQNTFSSSKKDSDSASIKPEKVASSSSSVNSMISWRSKGAEMFSKKNWGRARKNSEPTFSASKGLVASPIFGAGLEDAVRMSHIPGTPMVPAVLFRCAEYLEAKGIDEVGLYRVPGSHASVQKLKKMFDSGKDIKLLTMDAIDPNDIATLLKLYLRELPTPLLPAVFLEQFQSVISTDRQVCHSLRGILLRLPRTNYVVLSFLCHHLSRIAGYSEKTKMNTSNLAVVFAPTLSIGSVLFKALLGDYYDSDDTTESRDKGLKIVWGGLLQDFDYGVQEDWDDDDDSTGVQLTQSQSQSTPHLPLTPAQEFVNATQTAQSTPTEPQIRDSVAEDEAKLMAAMLLKEELAAKEAEDDETASNASESSSSIPCTDATIVSSPGMDTKDTLDSSSALLPMAPSPALTSTATATAAEQDLLPSSTLSSPSALAIPLSAQTPSSTSASTDASAHPEPPIINITIDAGSLFSPLAAEFAPETLDAPLMKTTEATMSESPIQLPASAKELNKIAEDVQNILRASGDDLVAVPEAERTIENTLLRLQEAQSQAAAKQTQCTFPAMVHLDKDVRDAATEAKKSLQNAWSALFSRRDVYEILRKLDRGSATERALDPEIQRLLKHTLRLFERHGAGLSEQDQKKLMQMRTEISGLELDFQKGLNEDTTDILITADELEGCTESWLSGLTRIEKNGEQYYKVTMKTPDILNVSRSAVLPETRKRVAVTYRKVCTSTNGPILERLIRLRHEAATLLGYKNHASYQLDINMAKKVETVEEFLETITNSISEKRESDKKVLLELKRADYEKRGWSSQFDGELYSWDVKYYQEILFKERYAVDNSLIQEYFELEHVRDQIMAVYSKIFQLRFEQIPGKYWADDVTLFAVYDQKAQDEAGEGHDDSSVFKIGYFYLDLFPRPGKYAHQCVVPLRPSYVDSTNGVRQLPVAVNVGNLSRPTADRPALLKHSEANTFFHEFGHVCHAMSSKARYSLFNFSWSVVPYPTSLAMDFLEVPSIMLENWLWEPTVLKQLGRHYKTGDELPTDLIQSLVKTRKVLKGLLFSQQIAVTAIDIKLHSIAPDQRQKSIPDLWRDMSESIVGVKLENEPGVNPACQLYHIAMGYDAGYYVYAWSEMHAHDLYTRFTDKTNDSQEATRALDSALGREYWEKVLVPGATVEPIDLLRDFLGREPNAQAFQRYLTEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUK9</accession>
    <name>A0A9P6MUK9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">methylcrotonoyl-CoA carboxylase</fullName>
            <ecNumber evidence="2">6.4.1.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">3-methylcrotonyl-CoA carboxylase 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_010596</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>3-methylbut-2-enoyl-CoA + hydrogencarbonate + ATP = 3-methyl-(2E)-glutaconyl-CoA + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13589"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57344"/>
            <dbReference type="ChEBI" id="CHEBI:57346"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.4.1.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid degradation; L-leucine degradation; (S)-3-hydroxy-3-methylglutaryl-CoA from 3-isovaleryl-CoA: step 2/3.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.4.1.4" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010000753">
        <property type="protein sequence ID" value="KAG0014193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUK9"/>
    <dbReference type="OrthoDB" id="439921at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004485">
        <property type="term" value="F:methylcrotonoyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.226.10:FF:000021">
        <property type="entry name" value="Acetyl-CoA carboxylase carboxyltransferase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.226.10:FF:000030">
        <property type="entry name" value="Acetyl-CoA carboxylase carboxyltransferase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034733">
        <property type="entry name" value="AcCoA_carboxyl_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011763">
        <property type="entry name" value="COA_CT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011762">
        <property type="entry name" value="COA_CT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045190">
        <property type="entry name" value="MCCB/AccD1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22855">
        <property type="entry name" value="ACETYL, PROPIONYL, PYRUVATE, AND GLUTACONYL CARBOXYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22855:SF46">
        <property type="entry name" value="METHYLCROTONOYL-COA CARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01039">
        <property type="entry name" value="Carboxyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50989">
        <property type="entry name" value="COA_CT_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50980">
        <property type="entry name" value="COA_CT_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CoA carboxyltransferase N-terminal" evidence="6">
        <location>
            <begin position="30"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="CoA carboxyltransferase C-terminal" evidence="7">
        <location>
            <begin position="293"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00025711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00026116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00031237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00031404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00052347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0014193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="544" mass="59270" checksum="159F223C0ECE736D" modified="2023-09-13" version="1">MATNLGHYPKPTKSKVNTKSPEYQANYKEMLGLVDQLQERLHEATFEGSDRLIAQHHKRGNILARERVELLLDDDSPFMELCPLAGYGQEDMTVGGSIVAGIGLVCGVECMITANIPTLQGGAWNASTMVRGARISEIAWINRLPHIQLVQSAGANLAQQSRVFHPGGATFRHLAERSKAGLPSVAVVFGNATAGGAYTPGMSDYLVMVKGQAQVFLGGPPLVKMATGEITDAESLGGADMHSRKSGVSDQLALDEYHAIAMTREFVSGLNWTKQGKLPIRHLKGLFDQPLYDPDEILGIVSANIRIPFDALEVIIRLVDGSRFTQFKPLYGPNLICGWATIHGIPVGILANNNVIFPPEANKATQFIQLCNMRDTPILYLHNITGFMVGKKYEEEGIIKAGARFINAVSNSLVPCISIMMGASYGAGNYAMSGRAYNPRFLFSWPNSKCSVMGAEQLTGVLDIVMRDSAKKSGKVIDEEMAKASMEMFQAMVESESDVYWTSSRCIDDGVIDPRETRNILGFCLSVCYNTEVKGGNLYGVSRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUU8</accession>
    <name>A0A9P6MUU8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_010988</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000829">
        <property type="protein sequence ID" value="KAG0013563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUU8"/>
    <dbReference type="OrthoDB" id="2257100at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001080">
        <property type="term" value="P:nitrogen catabolite activation of transcription from RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903833">
        <property type="term" value="P:positive regulation of cellular response to amino acid starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12193">
        <property type="entry name" value="bZIP_GCN4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050946">
        <property type="entry name" value="AP-1_TF_bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11462">
        <property type="entry name" value="JUN TRANSCRIPTION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11462:SF35">
        <property type="entry name" value="TRANSCRIPTION FACTOR JRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07716">
        <property type="entry name" value="bZIP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BZIP" evidence="6">
        <location>
            <begin position="234"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="202"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="253"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="202"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0013563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="313" mass="32595" checksum="16A2EB88E2DB720D" modified="2023-09-13" version="1">MAVSIDFNMFDTTNIKLSKSADALESALAQFGKNTPSNNDSSAAGDLFTPSANSGNGFDEWLAADLAFGALSSDESSVSSSSPFSSLEDSPVLGFDSFGSTVGSSLFDIMPMCQPMNANGELPKVPKLPLLTSTAVQQAAAALNIPWSVELESAVMAQAALSAVASAPAPVPQTMASPILVPKTEPEEIGFASIPSSAATSRAASAAPAATPVKKSSKKRQLTPEEEAEEIIAKRAKNTDAARRSRLKKLIKLEGLEAKVSDLETANNALNMKIAILETEKNGFIAKDAEQTARIAQLEAQLAEAHAALANRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVK6</accession>
    <name>A0A9P6MVK6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">GDP-fucose protein O-fucosyltransferase 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_009878</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the glycosyltransferase 68 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000631">
        <property type="protein sequence ID" value="KAG0015409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVK6"/>
    <dbReference type="OrthoDB" id="1882547at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046922">
        <property type="term" value="F:peptide-O-fucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006004">
        <property type="term" value="P:fucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11296">
        <property type="entry name" value="O-FucT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019378">
        <property type="entry name" value="GDP-Fuc_O-FucTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045130">
        <property type="entry name" value="OFUT2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13398">
        <property type="entry name" value="GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13398:SF0">
        <property type="entry name" value="GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10250">
        <property type="entry name" value="O-FucT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0294">Fucose metabolism</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="193"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="529"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="214"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="230"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="532"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00026232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0015409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="737" mass="83552" checksum="D6922554F91AD4BB" modified="2023-09-13" version="1">MSRPTDHNTQEECHIPIMELHSPPSYTLNNNPISSTCITINHPNTDTNPQPMSSLSNPSSLKRRKSLQVHWHPSVNQLQAAKRRRQIVSLLSILAFFSSLTLVLFHYSGCDITTGQCQQTITSPSSSSVTGSSLVQGRKQILGPNAPPSSVGIFGSEGLLMDSEVMIATGGRRYKAHARGPWSFLYGHQKSNHHRVGEEGSREDENEAYGGDASRYEDESERQEVMESSESVENEMNEFEEEDYGLGETEVSGGRSEFDFEEDDVEDLTPTTEKSLKPIPQETYVDNWNEGSDLLSDEYIELEDDYIPLPRGDDYRRRQSLNGRMDPDTKYMTYLPDSGLSNQFHGMLRAMMLAKSLCRTLILPPITVSNYYYDYNKDSDDDEDKSQQNQPWSSYFELETFKYLTGVKIVELQDLRDPNQVSVSPQEGLKCQITSGVGSLRPLDSTAKEFVKQWKFDLSLTQLRTETSELDELVSALEGQDEKLLCISNAYNIIVSEDDEWDLFGRYLYFSPKFEGAFSRVLQGLNEEGMQRQVSHQQPEQQPEGSASTTEQRSDAIASKIQHNDNNDFYDHGRINSAIIPNINKLYRDLISRSDKNKASPLHGPYISIHAKRGDHIDYCQQHFQHDLRSCLPTTQELASTLHNIILSDPSLKGLPVYVSTNEDRPEELDEFRALGWQVLNHQEMGSKKQLGVFGPMMMDQIFMAKAQLLIGVRTSAFSKVGANRVEDWYARRAVFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVM5</accession>
    <name>A0A9P6MVM5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">T-complex-associated testis-expressed protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">TCTE1</name>
        <name evidence="3" type="ORF">BGZ80_010718</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000779">
        <property type="protein sequence ID" value="KAG0013988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVM5"/>
    <dbReference type="OrthoDB" id="333024at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052201">
        <property type="entry name" value="LRR-containing_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24111:SF0">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24111">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="417"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="489"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="417"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0013988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="549" mass="59203" checksum="90CD3B2B03B58B8E" modified="2023-09-13" version="1">MAWGGGNANSVESWVKRLHENDPSFTSLHILSFRRITSSELGQVFEALTSNTTLKEFYASGHSFDEAAAKVLALALEKNSTLERLNIGNDHLGANEGVVKFLCEGLSKNKGLIRLDLENKGFGGRSETSVKYLAEALERNEALQELVLARNKLTDQDIETLCNSLSHGKNKTLQKLDLCLNSFEEPGTKSIATLLASQNQIDGSAGGLNEIDLSDNEITEEGGRAIGQALESNKTLQRLRMSSCMDPPLPVEEGAEDKIQWDDDIQLLNKSLTSEQEQEIRMDGDGVLETIAAALKVNDTLQELWMDYCNISSIGATFLADALRHNQGLVTVRMRNNRIGNRGARAIGAALSPSAHAMSNSSSAYNTTLKNLELGSNKVGVLGWHGLVAASSLESLGLYENQIYTLHEALENQSLASPTAASVPATPTSPQSATIPNGSTNTSHQVLEKLVHLDVGCNGISREDYTQLGVCLIKGLLPSLIRLEIAGNGDRSQAPEVPGGGGDDDNDSEPHPEDPNDEQNAWERVTSSVEEARPNLAIHWKGAGAMQQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVX1</accession>
    <name>A0A9P6MVX1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">mRNA guanylyltransferase</fullName>
            <ecNumber evidence="2">2.7.7.50</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">CEG1_2</name>
        <name evidence="14" type="ORF">BGZ80_010056</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a 5'-end diphospho-ribonucleoside in mRNA + GTP + H(+) = a 5'-end (5'-triphosphoguanosine)-ribonucleoside in mRNA + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:67012"/>
            <dbReference type="Rhea" id="RHEA-COMP:17165"/>
            <dbReference type="Rhea" id="RHEA-COMP:17166"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:167616"/>
            <dbReference type="ChEBI" id="CHEBI:167617"/>
            <dbReference type="EC" id="2.7.7.50"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:67013"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.50" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010000660">
        <property type="protein sequence ID" value="KAG0015092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004484">
        <property type="term" value="F:mRNA guanylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006370">
        <property type="term" value="P:7-methylguanosine mRNA capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07895">
        <property type="entry name" value="Adenylation_mRNA_capping"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.30">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001339">
        <property type="entry name" value="mRNA_cap_enzyme_adenylation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013846">
        <property type="entry name" value="mRNA_cap_enzyme_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051029">
        <property type="entry name" value="mRNA_Capping_Enz/RNA_Phosphat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10367">
        <property type="entry name" value="MRNA-CAPPING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10367:SF17">
        <property type="entry name" value="MRNA-CAPPING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03919">
        <property type="entry name" value="mRNA_cap_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01331">
        <property type="entry name" value="mRNA_cap_enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56091">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7" id="KW-0506">mRNA capping</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="mRNA capping enzyme adenylation" evidence="12">
        <location>
            <begin position="45"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="mRNA capping enzyme C-terminal" evidence="13">
        <location>
            <begin position="235"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="354"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="822"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="973"/>
            <end position="1123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1198"/>
            <end position="1247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1277"/>
            <end position="1322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1343"/>
            <end position="1362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1383"/>
            <end position="1857"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="355"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="381"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="397"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="408"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="420"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="450"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="460"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="487"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="561"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="576"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="630"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="688"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="710"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="834"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="980"/>
            <end position="990"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1009"/>
            <end position="1061"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1076"/>
            <end position="1094"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="1277"/>
            <end position="1288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1384"/>
            <end position="1394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1411"/>
            <end position="1422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1528"/>
            <end position="1537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1562"/>
            <end position="1591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1635"/>
            <end position="1651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1657"/>
            <end position="1668"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1789"/>
            <end position="1825"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1846"/>
            <end position="1857"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF03919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0015092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1857" mass="204308" checksum="9AB60541CD8811BF" modified="2023-09-13" version="1" fragment="single">MSLTPRSSTPQMPFEFGVPIDANFRETLRSRIRALLQPKSEGLRSDEEYFVTEKVAGVRYMLLSTHTPKGPACFLIDRHYEISFVPQLLLPLRDNPTKYQNDTLLDGEMVVENDGNKKLLRFLVFDLIALNGVSVTQKTYNTRLGMMDQDVLAVQASKANEMKSKEPFTIERKPMQRSYGLNVILSGSKRHKHGGEGLIFVPVKQPYVPGISPKLLKWKSHTTAQFQIKVTQSKERKPLYCIHVKHGSGLKFYDYVTPEPPLAAEWHSSSPDGKIAEFWWDPQYQTQMFEKGYGLETRTGGWRFYRIREDKKDVDDEATLQAVVKGLDSLVTRQQLESQIDHIRTQWKAREAGISSNGNTAQSTQSTQSTQPTNRPAVRQLSISSSFSDNQPPPTTPSLNSPFLQSPSTTSHSGSHGYFSKKDRERKSSVDEHGSTGSLPAATPGTFSHPLPPKPPPFQPRQSSVDQSQTQSTSANSHSTKAEKESAASTTSTASPSTSASQPSDRKTTSPPPATTPTSAPPVSGAVVKNPLKLSQIPAHLQPIKPWMTTPPVPRAPPSDRGIKAIRTERRDSRDSNASGGESSPRSSASTTPVSRKSSLSTTETTKDSATATPSIATKTKEPASSREGPSNSASSPTSASHKDQPQTPTPAHTPTPVGMPRSSVTPAPPLTFSLPPTSIALPNSIPKNEEKKLPDEHRNAESSILNDGAELTLAETSTASLTPTKPLVENGDSSSTPTPVLGKRTYGPSTSIGEQSEDSLAQRRKLSDGTLSSPRTEAVMTGIGTLNLIASQSPKPIHSSPLAAQDNKKLSPLLLPLSSPGAIAVGSDDKQSSPRPSHSSAPKFTASSKLLHEISVYSDPTLHENNISEVKEEKQAMEVAPGLVQTPNNALEHKPHVAATAVIEDVEMREVDMGTAPLPTLALTHAERMAYEPPSDQEKKQAIEKASAQAMYRIEKQGELQAAKESKIREDVERFKEKSRIRKEKAQKRKLQEVNEAPIQDRRAQPVRQINQQQGKQSNSDSALLRGQSQDPQRLVYQTRQSKAAFRTETQQQSAQNSPKVQPRAAQYSGNTKEQVQSSQDSLSQSSVQRDQQATANDLDSIPPQERAEQQSHGISDQKMLEPGDANLHHRRINSMDRQAHTSQPHNPPTPEQRGDIEQYSHLYAKRLDVGQHSDPNHRRSHSDIGVMYKPVSAAIAQPQSSASGPFPVSGEPQVRSELEHRQGLYSSQNPSAPAPFRSDIDSPRMRNNIPFLTSTKEPVPTKLEYKAKLQFILNDEDSGPDIDEDDARERRASPGRSNWGYDQDSVQRAHAQSEYSTRSDYSLQEHQGIFGHSNVPASAVEPESALALAHRQQSKKQKTTQEFGAMEQNFNHRLDEHEYHMRQSQMQSMSSRPTAQQTQRPMPPVDHWPQQVHSQHSHSPQPMPGGQSHPPNHAQAHSMVRRIPAEAQGPPTQQPMSHPSARPMYQTSEHLQHGNPPGRPPHVDQYPMLGSGPAQDGPRSASDRPTHSRHSSLSKPGIAPEHSHPQGLSYQNSLSKAPPAHSNADQFGRGYPPVAHPPVQARSSAQAQLQQAQGQYHPQQQQQQQQQQAPVGTATRKNIPGEHHAGAFGPPQTSSAHPGYDSRPTHTQHLHPRQQQAIQQQQQQQQHLQHPPPNRHSEQEPPHDVEVLPGYHKQSQVPHQVRSGHNDQAGAPASHGYYEHEGHGASHGSGRSTMYGSQPLHPSAAQERQGVSYAPYRAAGTSHDQPYRSYPGSSARQPPGIDLGPKDDHVRGGSGGRGSMGHLPPEHSSLSHSSQRQQHSQHMSHGSASFHQQQQQQQYPPQQKLMHVQDHPHSQYPPQHHQHNAPTKISSPRHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MW91</accession>
    <name>A0A9P6MW91_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BGZ80_009616</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000591">
        <property type="protein sequence ID" value="KAG0015824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="245989at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03233">
        <property type="entry name" value="ABCG_PDR_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03232">
        <property type="entry name" value="ABCG_PDR_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000054">
        <property type="entry name" value="ABC multidrug transporter atrF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029481">
        <property type="entry name" value="ABC_trans_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034001">
        <property type="entry name" value="ABCG_PDR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034003">
        <property type="entry name" value="ABCG_PDR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010929">
        <property type="entry name" value="PDR_CDR_ABC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19241">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14510">
        <property type="entry name" value="ABC_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06422">
        <property type="entry name" value="PDR_CDR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="535"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="564"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="605"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="641"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="674"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="699"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="776"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1191"/>
            <end position="1212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1224"/>
            <end position="1246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1267"/>
            <end position="1294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1300"/>
            <end position="1324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1336"/>
            <end position="1358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1457"/>
            <end position="1478"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="157"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="860"/>
            <end position="1107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0015824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1483" mass="166606" checksum="A61313931E491254" modified="2023-09-13" version="1">MSNPTQSTSATSEEKSPTGILRNNSYHRQETAIPIGDMKAEVQEEEENSDAGTYEDAISGRWGEGPSRVNVVGAENSFKTLERQLTRRSSIFRTQTGEKKPGDNGDFDLTDYLRDVIPRAEDAGIKRRNLGVVWENLEVLGEGVGAQYISTFATPFIGLTNLINPYFWAKKAFSKSESPRTVTKTILHPMNGYCKDGEMILVLGRPGAGCSTLLRVLANDRKNYKKVNGDVTYGPFSAEEISLYRGEVLYNQEDDFHYPTLTVRQTLTTALKTKTPGKRLPELASKKQFVDEFLDVLTKMYGLTKQVETIVGNAFIRGVSGGERKRLSIAEQMATRSSVNMWDGSTRGLDASSALDYVKSLRVMTNLMNKATMVSIYQASENIYDLFDKVLLLYDGRCIYLGPANQARQYFIDLGFECPARQTTADFLTAVTDSHERKARRGFEGRIPQTPKQFEDAFKSSAFYTSEEKNRVNYQDSVKEHNPASEFKAATKQFKQKHVSVESPYTINFFGQVKVLTIRQYQLTRGDMASVISRYASNVIKAIVVGSVFLKLKADATGTFTRGGVLFFSLLFNALISQAELPMAMQGRPILYKHKNFAMYRPSAFAVGQICIDIPLIIAQVLLFSVVIYFMTGLQLEAGKWFFFCLTLFLAALCMTAFFRMWAAISPTFDQASGNSGLILLALILYSGYMIPYQAMHPWLMWIFWINPLAYAFKALMSNEMRGLSFECSNAMIPSGPTYTDVQYQVCALSGSQPGMTSVDGSEYLYSSYRYNTDQMWYDIIALICFWLLFVGITCYALEKIEFGKGGFSTNVFKKGAIIADKPEDEESGPAHSNSTLSVANTAGKGHSGIELEMAKGSVFAWENLDYVVPYKADPSGKKQLLNGIAGLVKPGTMTALMGSSGAGKTTLLDVLAQRKNIGTVTGQIEVDGEPLRRDFQRTTGYCEQLDVHVPQCTVREALQFSARLRQPADVPEAEKDAYVEEIINILEMGDIADALIGTTESGLGISVEERKRLTIGVELVAKPKLLFLDEPTSGLDAQASYNIMRFMRKLTDQGQAILCTIHQPSSQLFAFFDDLLLLAKGGKTVFFGELGHDCQDLIRYFEKNGAPTCASDANPAEYILDVVNARNSELNWPEIWLNSPERSQLLIDIKATRKTGTASNDESLEFAATTSMQFKYVFQRMIRTYWRLPAYNFGRIFMMIIFALLNGFSFYKLGTSKVDLQSRVFVIFQIMVMGALLVNMTEPRFHMERQWFYREFAGKYYNWKPFAFSIIAIEIPYVVLTATIFFAVFYWTVGFVSESILIFFTWLMIVIFCLFAITLGQLIAALTPSTTVAALLNPFIFSSLNLFCGVMISKALMPKFWSSWLYWLDPYHYIIEALVSVQLHDVPVACKSDEFSIFNAPPGQTCGSYAATFLEVATGYINNPNATSRCEYCQYSYGQDFYESLSMDFANRWRNLGIICLYLVFNICMVVTAIRFVRWDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWP4</accession>
    <name>A0A9P6MWP4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_009118</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000521">
        <property type="protein sequence ID" value="KAG0016575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWP4"/>
    <dbReference type="OrthoDB" id="655030at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050562">
        <property type="entry name" value="FAD_mOase_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356:SF2">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356">
        <property type="entry name" value="FAD-DEPENDENT MONOOXYGENASE ASQG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="44"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="7"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="21"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0016575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="472" mass="51966" checksum="308B05171BCCBEA7" modified="2023-09-13" version="1">MPFSYKSGRSNTDYSNQTNPSIATSSSDASSTYPHTSHVEEPTLKVLIVGAGIGGLLLGYCLERAGIDYVILERAPRPHTTKTTIQFTANTLHAIDQLGLLEEVLKISKPITGVTLHKHSMSVVGRIDFLFHKERAEFCRILMSRMRPDRIQWGRKVLETVSGDIGVQCRCANGYVVQGDILVGADGAYSAVRQNLFRNLKEKSLLPKSDMESLKFTQNAIIGMTEPLDPVDFPEAATEFGRCQIVIGKDSSPYTLWITPTSENRLTWSVTGLLITETKGEQNLMVSQFGPEEVRKTCNLIESLESPIGGSLATLIAHTPEENMIKILVEEKHYKTWHHGRTVLMGDACHKFVSFSGQGPEQAMLDAICLANVFYGLKKPYPFADITEAFAMYHELRSPVSKAAVQTSGQMANLINGQGLGSEIKRKLVFNLPMWMQALSVDKAQTRPLLHFLPAIPGRGSKSVGAPSVKSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWU9</accession>
    <name>A0A9P6MWU9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_009039</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000513">
        <property type="protein sequence ID" value="KAG0016668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWU9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00866">
        <property type="entry name" value="PEBP_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.280.10">
        <property type="entry name" value="PEBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008914">
        <property type="entry name" value="PEBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036610">
        <property type="entry name" value="PEBP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035810">
        <property type="entry name" value="PEBP_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY MULTIDRUG TRANSPORTER MFSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718:SF9">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY MULTIDRUG TRANSPORTER MFSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01161">
        <property type="entry name" value="PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49777">
        <property type="entry name" value="PEBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="419"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="457"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="486"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="515"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="546"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="573"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="610"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="641"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="681"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="721"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="420"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="776"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="783"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0016668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="823" mass="91087" checksum="7E9A2E8A62F9F0C8" modified="2023-09-13" version="1" fragment="single">SIRSFSVQAVSRNAVESTYKAPALGVNKTYDEALKIIAEDKLKRLNEVKNLKESLAQLMKDTPSDTRDSKIAQLKENIFKQEAYAEINDPEIQWRFKNGHIDMSKAVFRYLKSKQFQRETLPVIQQRITQMFVTPDLLPPFTPSLNVQLDFSGSASKEESGAPTNYFETGSYLLPRNTIKEPRVNVTSFHSEQKYYTIAMVDPDVPDVENQSFKQQLHWLISNVSLSATQPDLVKENADVLLPYLPPHPPMGTKYHRYTLLVAEQPNGGQEKIQIEKDQISRETTLQELCSQYNLSVKGLTFFRQVWDKDVSRIYKDILQQSEPVYGKLPKVDELLDETGQKKKKFIHLAHIQESRPRRLIVHKQNIHVNTLLMTHNDSALTTSNNTVISLHDDPSSLKEKDPVVLTNFQKICLKFEPLMLYVVSMAQFLDIVNGASMTVAMLPISRELNFEVQQQQWLISSYALSFGGLLLIAGRMGDLFGHRRVFLSGLFWFGIWSLVNGFSKSPVMLCISRAFQGMGAAAQIPTALALIAIKYPAGKARTRALSVFGAIGAMGAVTGLLLSGALTSTIGWQWIFFLSAIMSSILFVLGVFAIPSASGLHGDSPRIDVGGAFTVTGALGFILLACSAILFSFVTPTSTYWVLPFLAMIVNVFGLGLIMLPAQITALRDASDDDQGVVGAIYNVGLQIGAPFGLAILTVISGKLNGENPGPDRMHGYKYSLIGDAAFAILGFLLTLIFLPHVKPGVSPKVSSLEEGGVPGSEMDSVTEIEVVSADQGLPQKQGLNEITQKQEFNEIPQKQELKDAKEELLEEVHAKTDLSLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXI8</accession>
    <name>A0A9P6MXI8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">THO complex subunit 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">THO2</name>
        <name evidence="2" type="ORF">BGZ80_008125</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000431">
        <property type="protein sequence ID" value="KAG0017608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXI8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000445">
        <property type="term" value="C:THO complex part of transcription export complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040007">
        <property type="entry name" value="Tho2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032302">
        <property type="entry name" value="THOC2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21597:SF0">
        <property type="entry name" value="THO COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21597">
        <property type="entry name" value="THO2 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16134">
        <property type="entry name" value="THOC2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="THO complex subunit 2 N-terminal" evidence="1">
        <location>
            <begin position="2"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0017608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="291" mass="32429" checksum="184DDEE785F4ED48" modified="2023-09-13" version="1">MEEQIAQWKESGSHEGLLNYATAILNTLSNDLPHPVAAVIQLVLLEALSNGLTTTQVASFLSQLSGRRSGPSSADVASIIVDLFWVMEVEIEVENENRATNSGRLEKLCLLAKAIIQQGFIPENIMKERWEISFLEQVGLIQNARLFTKRVIRINTAQLYKQHKYNLLQEESEGYSKLITELASGTADCDDDMQIVSRASTVLDNVISLIGYFDLDPNRVLAIALDVFAASITTHYRFFIQFLKMSPWSSQSTGDRITSKNKACAQILGFMFQDLQATPRESPQDAPELGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZ40</accession>
    <name>A0A9P6MZ40_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007937</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000417">
        <property type="protein sequence ID" value="KAG0017769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZ40"/>
    <dbReference type="OrthoDB" id="2447638at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040381067" evidence="1">
        <location>
            <begin position="23"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0017769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="161" mass="15773" checksum="482F9B3ADEC4BC27" modified="2023-09-13" version="1">MSSVKSILVSLALAMVVLQVTATSATPCTSDLGAGIGGIGMGIRGIGPVGFGTGVGFSGGYGSQGLPTVVPIPPTTLAPETNFAPISNVLPVVNLFPVDVNDYSCEGDYGRYNYGGDFGSSLYGGCDGFDSFGGCRGGFGFGGYGGIGGLGGINGIGGYGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZ73</accession>
    <name>A0A9P6MZ73_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_007871</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000411">
        <property type="protein sequence ID" value="KAG0017834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZ73"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24126">
        <property type="entry name" value="ANKYRIN REPEAT, PH AND SEC7 DOMAIN CONTAINING PROTEIN SECG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="673"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="917"/>
            <end position="971"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="924"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="948"/>
            <end position="964"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0017834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="971" mass="110284" checksum="920D7B4EA2DC9594" modified="2023-09-13" version="1">MAQDRLRLHEEDSDLERNSISISISSSINSSISNNSINASIDNVLSRARYAISDASLESDFFNILVLGERQSGKSTLIEAIKNYPNQDVLEHGIPTYTPTTAVTSTCITTTLPRFSIFENADAQDDRSRPKRLNNNDVRQYLSIVREEYEQQKSRLHLQKDPQTLNPYKFNFRLIDTPGLDFVKDGSKKILEGEGSGVFVSKTLPAIVEQLGPTCAVHLVLLIVPDPDNYDNSDAVNFYRDMLPVFDFITVVAHRETEGDQATPVSKAQPRHKSSYGDSYADQIHLIIGNMFIRDDPIRDYLARNDIRRILELALLNEPVFMQPKKPSFIKDLDNFLEDRYFELLKTIHNAVATAKESSPFHTILQLTKVQCDEYTRKEATLLSSPLKLVFSRRFENTWDVSSTDNSIEVEMESTEGEITHVDILQHNIKIVKQDGGVGAHRLRLAFRWTSAFYGVFDIRIYVNTTATSRHSNDIQKNITDAIQNVTSNSKSPSNQHKLIMELLQRYRQLHLMRHLALIPIVYPETIQILSICNIDQATPIDLFQCVEDLEKVYLGAIDAYTPKPTFPGKAFTNVIVDGGNYREAVFPTINRFQMHLLVRRAMTPWSKNEQNPIPFDASLIRPRHLAPIMHNTVISRNRLENIWQCAKRGDLALVKYHLQKDPSLINTPWKFDGRSVLISACASSRPFELVEFLVQQGAQVNSKDMFLKRTALHTLCEEGGITKDNWEGSAIAIPQADLDATEQDVLATMRFLLDNGATVDAKNHWKETPLMRLLTGRDCPLMVQELYSRGADSRLKSIKDLYPHGTALCYAAHYGRVKSLKWMIENDLLLSDEANIKDALRWANRSHNSEPPGGAKWNATIARRKEEHKVEAIRLLKSWLGNSGTTKRKALAKEISTQSEEDWWRRMSGIVEDVQNKMESEPSPATSTGNSKIPPSMLKHWKEVQGLSESLSQNSDKPSSPNNWMKWLPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZG8</accession>
    <name>A0A9P6MZG8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Transcription regulator Rua1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_007153</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000361">
        <property type="protein sequence ID" value="KAG0018455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZG8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028012">
        <property type="entry name" value="Rua1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28125">
        <property type="entry name" value="MEIOTIC EXPRESSION UP-REGULATED PROTEIN 26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28125:SF3">
        <property type="entry name" value="TRANSCRIPTION REGULATOR RUA1 C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14616">
        <property type="entry name" value="Rua1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transcription regulator Rua1 C-terminal" evidence="2">
        <location>
            <begin position="783"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="241"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="421"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="492"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="695"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="886"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="253"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="428"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="492"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="888"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="913"/>
            <end position="927"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0018455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="927" mass="101177" checksum="55C1B67A59D3D088" modified="2023-09-13" version="1">MMMEYPQQPLDLRQFQPQQQPQQQQVTTQSLVDPISSASLGPLAMESVHPFHTTPLPMSVGPLTPGNMSDTPFPAQNTMPHPITATSRPLWFENSGLTHRASFHSLLSAGGKDERLRARQDRGSIISLASTIGDDSPSDLNSLDMDHPLGELHSQQGSTGMGYDGEEYDHHGIGTSLAMMFMEFMPPSRSSPGDTSVEGDLSSTQPSRSNSVMLDPATIMKVNSMFEMGEEPLHLQSDRYSGVSVQPHPMSKESFQADASQENANRTQSITPSQHPNETEGMLPSIWSGSIDLLATPVHPFSIPPYMEERSQPLATANPALLDNASTRERESLTQQVLQANLQSQMPTYSSAPMYFTNNDGQSVMSGQVPGAEYLKNPNSLTPPLHPQQQHQLGQKMYINPAGSSNLEKVTRIRNRTISSPAGSFQYSPSSMGSTSTSVNMARPPSGLSFGPMPVRERKRSLLDADMARGLDQVRQSLPGAQLTLDSSHLTAASGASNNNGGNSNINNGSGGISNNGSTEGKSILHMPFNIKQEPLDQSLVGLGLSGSSPSDAPPEETYHRKRTKSVDMYSSYMGTLSSFTPPPQSTNVVPVSMDMNSNVTATLSQGTSVQNWQPPEMALHLQMYQNNMHLNGLSSAMPPSTMPMHMQMNGPIHPHQMSPSAMGPESNLYIQNVGLPDQGQTLRHSLSHDRLGTGHGILQQQAPGVKAKTKAKATKSSTKPSKIKGRSMSMGDALDPENLGTGEDEDAAQNEEKNNNSGSDFEGSEIHGDRTARKQKLRYEGDQYTPQWVRNTGQAKEGFCDTCTPGKWLQLKNSAFWYHKQFFHGISSVSGKLFSSPVQTRQMEQEDVEGLCHQCNEWIPISNHKRQNSMLWYRHAHKCHIYHKPKTQGQSSNRSSFSAGQPLPTFPEGHPLTQNGGNETAPANNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZZ9</accession>
    <name>A0A9P6MZZ9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_005579</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000275">
        <property type="protein sequence ID" value="KAG0019581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZZ9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0089701">
        <property type="term" value="C:U2AF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000066">
        <property type="entry name" value="Splicing factor u2af 23 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003954">
        <property type="entry name" value="RRM_euk-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009145">
        <property type="entry name" value="U2AF_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12620">
        <property type="entry name" value="U2 SNRNP AUXILIARY FACTOR, SMALL SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01848">
        <property type="entry name" value="U2AUXFACTOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00361">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="8">
        <location>
            <begin position="12"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="44"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="6">
        <location>
            <begin position="12"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0019581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="191" mass="21886" checksum="8F00876C92B83B52" modified="2023-09-13" version="1">MATYLASIYGTEKDKVNCSFYFKIGACRHGDRCSRKHVKPNFSQTILIPNVYHNPSHDANCTMGKQEIQEDFDNIYEDFFVELAKYGEIEEMHVCDNIGDHLVGNIYARFKYEEDAGNAVESLNNRFYAGRPLWAELSPVTDFREGNTDFFRFTLDLEPFIFKLAVANMKIRNALEAVYATSCTSNQQTGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N018</accession>
    <name>A0A9P6N018_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Core Histone H2A/H2B/H3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_006732</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the NFYC/HAP5 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000334">
        <property type="protein sequence ID" value="KAG0018785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N018"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016602">
        <property type="term" value="C:CCAAT-binding factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22908">
        <property type="entry name" value="HFD_NFYC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000006">
        <property type="entry name" value="Nuclear transcription factor Y subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050568">
        <property type="entry name" value="Transcr_DNA_Rep_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10252">
        <property type="entry name" value="HISTONE-LIKE TRANSCRIPTION FACTOR CCAAT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10252:SF8">
        <property type="entry name" value="NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0010">Activator</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="9">
        <location>
            <begin position="102"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="193"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="279"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="21"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="300"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0018785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="311" mass="35091" checksum="8F383B7293372BDF" modified="2023-09-13" version="1">MSRQRQTSGGSSYDPTSTTSQYYQQQAQLPPQQQPQQQQQQQQQQQQQQYHIMAPVGHAPPPPLQHYHDPSLAHQQPMQQAHMHMLQSFWMNQMHEVENVPQDYKLHHLPLARIKKVMKTDEDVKAKMISAEAPLIFDKGCEIFITELTIRAWIHAEENKRRTLQRSDIAAAISKTDMFDFLIDIVPREEYKMGKESKTSTAGGSESRRSQESFPPIGSTGAPGSVPNTAAPGPGSMAPGGFEGYAYPYGVLEGGTFAVGHGEALDPYQQQQQQLQLQYMRAQMAQQGHQHPSPQRYDFQAQQQTQQHSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0C5</accession>
    <name>A0A9P6N0C5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chromosome 5 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006128</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000301">
        <property type="protein sequence ID" value="KAG0019235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0C5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050307">
        <property type="entry name" value="Sterol_Desaturase_Related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11863">
        <property type="entry name" value="STEROL DESATURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0019235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="280" mass="32152" checksum="308D63D2E819120B" modified="2023-09-13" version="1">MAASSELKHVDPDQVLDDQAPVQDEWGPIVSHHKAPFEVGDVFFYSVMISLFFGGLHLYGEQFWAHILATYPKPVIILGGSFIISEVGFWFWVTLLGVLDLYQFPKSFWRYKIQPLKVPTWEWYTKALWVVLQNQFLVGVPTGLLLYKLLEWRGNPIGMELPTIWDLAKESIGFLAIEEIGFYYGHRLLHHPKLYKRIHKQHHLYTAPIGIAGQTNAINSHCGFHLPLFPSPLAHDYHHEVFNKNYGPVGILDWLHGTAGSRELTLEKKKQREAAQAKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0F5</accession>
    <name>A0A9P6N0F5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_003894</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000206">
        <property type="protein sequence ID" value="KAG0020613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0F5"/>
    <dbReference type="OrthoDB" id="3210850at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38848">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 3 PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38848:SF3">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 3 PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="22"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="52"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="87"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="170"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="211"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="263"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0020613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="322" mass="35671" checksum="322D09847059FB5A" modified="2023-09-13" version="1">MAGHIFNSSDPMYLFQPDPMDIGALALFLSCVSVMSFMIGRKTSVPISSLNYARGLVIALYITSWLFSFVVAILAQTSDNHPVSCTVSNFVCIFLYAASKVFIYLFMVERAHVVTDVGVSRWNSRMFKFNIALLAPFSVIVAFVVKFRVSEIDDAGYCRIGLQTQASVPFITYDILINVWLTFLFMRSLISSTSKIQGDTGRKLRAVARRTLVGAIVSLILTTSNIASVVAFNGHERSALCLALCTLDVTLNAVTIHWVTNPRKGSETSERSTPNKDWPSNVDSVMMGGQEVSPLRSHFSISIESHVEEYQQVHGLGRVHNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0L1</accession>
    <name>A0A9P6N0L1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_005722</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000281">
        <property type="protein sequence ID" value="KAG0019514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0L1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051615">
        <property type="entry name" value="Transcr_Regulatory_Elem"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313:SF79">
        <property type="entry name" value="C6 FINGER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="60"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="433"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="890"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="19"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="37"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="435"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="903"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="930"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0019514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="930" mass="103512" checksum="68650F7F4E199743" modified="2023-09-13" version="1" fragment="single">MAPDSIDGHSSSHSKTKNSRQSSAPDTNGASSSSPAPEKESDSTESNKKAPTKRIRIPIACVNCRFKKIKCDGQSPCSHCEKFKAECVYPAATKPINHEYVEALENRLKSVESHLQGILSMGLGDPGSPPMDTFPDNTVESTLPLTGSSSRTASIIMSAIEPPSSSNIVNINQGHFSSTNRVLPTSHSAANLTVSLAQLTDDVAPGEEDSVFNTLQLVIGKLRVDRDGTAKYLPNFREYNERSYTDSRNYGSNASQQRPSSLSEIANLSWESVDLPRPYTLPTNILSLKATQALINIYFNSVHTFLPILHKADFLSLCHNSEYRVPPFLLLAICAVASRHATESERQSIAKLVSLGDHHILFDHARALIDTFIDIPRISTIQGLLLLSYYQIKEKRAGHFFRVRVYLNMAIRMAQDMGLPRDLRSGVDKVDTALTGDSTSTNTGAPLSRSFTGPQPQQLVEQSRRNNRNSLNSKKSITTTQQEGRLAWLGCFFLDGLINSMLGLDYGVTHAHLELRKLIREANYSTTTQGASLIFWYLHLDLVQLYRRICEMYRVLATTSQNAGSAVNTILKGTEILSIGNALENWIKSLPIHLVYTRKSVWATADGDNLPSYYSLYLHRFYYSLQLLLYRPLISFKAYRGDLSKASSAMGKCATAAELLTEIGETIFQNYSWPWPGGGFFAYQMLQALEIHVYLMITHARAEAKDMYLRTINLIQGYATLAKLETLGRDIIAIRQAVDSMATGSVPATLKHTPLSILRQIQQPQQQESTVVAKTPFASDDPYASAISMCKSPSSLTQYTQQYLNINPQHQGPHPGFMGSADDTQRFQLSHSSATLHLPASNVGPMMPGVTPHMQPGTGFSMNGFETVPSDGQGQESPMTLYLYDMETMPIPTNDQQQEHDQQQQQQQQEQQQDRQQQQYQQQQQYQQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N151</accession>
    <name>A0A9P6N151_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peroxisome chaperone and import receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">PEX19_2</name>
        <name evidence="2" type="ORF">BGZ80_005112</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000254">
        <property type="protein sequence ID" value="KAG0019894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N151"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033328">
        <property type="term" value="F:peroxisome membrane targeting sequence binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045046">
        <property type="term" value="P:protein import into peroxisome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.900">
        <property type="entry name" value="Pex19, mPTS binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006708">
        <property type="entry name" value="Pex19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038322">
        <property type="entry name" value="Pex19_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12774">
        <property type="entry name" value="PEROXISOMAL BIOGENESIS FACTOR 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12774:SF2">
        <property type="entry name" value="PEROXISOMAL BIOGENESIS FACTOR 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04614">
        <property type="entry name" value="Pex19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0675">Receptor</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="283"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="28"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0019894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="306" mass="33487" checksum="84275EA950063617" modified="2023-09-13" version="1">MRTNLNRALGQNFVESVSGTKGALDGFTSSKPVPASTSTAPPPASSASSSSKAKSVDKSTKAAQDNDGDDNDDDDELDDDLGLDDEFTKSLASGMEELMKEMNGNPELKESFEEIFRGLDVNGKAPAATAAGADSKSFQDRIARTMDKLKDSSDQVEAQVAEESEEALMAEMMRQMEGMAEGGDFQNVLEGMMEQLMSKDILYEPMLDLKQKYPDWLANNKEKLSAEEYARYEKQYGYVKQIVEFFDRPDFDDKSDAQAKSIIDLMQGMQDCGQPPAEILGELAPGMELGPDGAPKMPDMPECNMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N171</accession>
    <name>A0A9P6N171_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CYTH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005051</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000251">
        <property type="protein sequence ID" value="KAG0019939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N171"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016462">
        <property type="term" value="F:pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.320.10">
        <property type="entry name" value="Hypothetical Protein Pfu-838710-001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033469">
        <property type="entry name" value="CYTH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023577">
        <property type="entry name" value="CYTH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34948">
        <property type="entry name" value="OS08G0299200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34948:SF2">
        <property type="entry name" value="TRIPHOSPHATE TUNNEL METALLOENZYME 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01928">
        <property type="entry name" value="CYTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55154">
        <property type="entry name" value="CYTH-like phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51707">
        <property type="entry name" value="CYTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CYTH" evidence="1">
        <location>
            <begin position="1"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0019939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="176" mass="20243" checksum="5556318A494D62EE" modified="2023-09-13" version="1">MEIEIKIRLPTEEDTARLERALGGSPISSEDQDNVFFEGFHKELIKNKLVFRIRIIEKSGKDPVAVVALKGNAVLVDGIAKVEEEEEEIDCKVAKQIIDNPNLILEVAKSHRLLKKIVERVPCKDGYTHMGRFKNVRHKYQWQEYVVEVDRTEYPHGMAYEVEIESTDPENAKARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1I7</accession>
    <name>A0A9P6N1I7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_004181</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000216">
        <property type="protein sequence ID" value="KAG0020443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1I7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="19"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="118"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="186"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="33"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="118"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="138"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="153"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0020443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="419" mass="45961" checksum="AA509C08992AEA7A" modified="2023-09-13" version="1">MKSRFSRLWDRCRQVVPSVSLDDSSWGGGNRTPRATSPETLASPSTQPDRPCSPLSKATVASPADVNIGYSELSLEAFDSWRNGFSASLQHRRPRRTRHTSLVVEKAQPSITLVNSLASTSAPASSESLTSEHQAEDSSSPNKSASSPPQGDSIASSDADTCHSSITSLEPNPQRHTAMLNVRWNIMEGREELEQYVAQVQKLELDRIELIGSQSRKRQERDVLESEIETLERLIREQSRGNEAGSSLGLITENCCPAASSVGVFVPNNNSPVAYSISTHTPTSSLRTITSNSGISTLSPTLSSVLPFSLSSPTIVATVTTATDLLPSPPPPPAQQQLQPKLTSSSMLICARCHQRALLLEKRTLLSQIHKEMEKIQRKINYMTSDIKHLKRTFIMPIESCLAKDRDEWTRLLSDQMAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N213</accession>
    <name>A0A9P6N213_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_000612</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000113">
        <property type="protein sequence ID" value="KAG0022278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N213"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13983">
        <property type="entry name" value="STKc_WNK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:001565">
        <property type="entry name" value="WNK protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050588">
        <property type="entry name" value="WNK_Ser-Thr_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13902">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE WNK WITH NO LYSINE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="29"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="340"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="622"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="759"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="885"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="343"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="887"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="914"/>
            <end position="923"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0022278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="980" mass="108115" checksum="1FFFE48A288C774B" modified="2023-09-13" version="1">MASTAMQGDLTDDSDNEGPLETDPSSRYQRCDEVLGEGAYKLVYRACDLEVGNEVAWNQLRLDNLTKREARKILSEIEILQSIRNEHIINFYSSWLTPTVNGGERIVFITELMSSGTLKQYLKKTLKGALKPKVVKAWCRQILQGLAYLHARDPPIIHRDLKCDNIFINGNNGQLKIGDLGLAVVRRRTHVSSVLGTPEFMAPELYDEKYNEKVDIYAFGMCVLEMVTKEYPYSECTNQAQIYRKVTQGIMPQALEQVQDPEIKEFINCCLDHNPCTRPSAQELLDSDFLKPCLAEGEGSIPLRSDTPVSIVQPPTHVTIPEAEFTLTTVDADNKTYHIRSNLPLTPTSPQQDPLATNQPESGSQTPSVAGNQKPAPNPNPAHSHTNSEVCSIQVLQYGEAVGSRLNLKMVCTCPVAGVDGPTGTHEIKFPFDLEVDTVEDVVSEMIREKILSADDKGEAMSRMDVLVTNILQEKGQAKKVEEREVPTKKVSSLNHTRAVLPSALPSSSSEVKVDLVPLSHVALPVQQAEALPAHHPVQHPIQQSAQLPVQLPAQTPVQTPAQRTATAIRPWSPPLAPRINHALQIPPRPKSVHDLNHAVARESKPTSSSMSGISVPMMQQLSNASSNRPRERQRSISTTAFENEDDIGYTSPYRHGVSGSSVKSHRRTPSCDTSAAISKAISVPASLRIFNPPSDSTGGGRHRAQSDLGQFMASAPSFSSLLTQPTPTSETPSIASVVLSLGISSTSAIASNNNIASTFAGSKNEPEPRGEDTDSGISSGVSSPVSMGLNSIRRHEQLEPPSNAPIEIPQLVPVVQQDLLSPLSAIRAPSHTQIDDSMHPMSSSISSDGSFGGMMMMTVEAKRDIELWSDNVRRTRDQVVPTAEYPNHRSPEYPHHHIQERNGSTSSLGYPDMSDEKDEVEDEDLRVLLEQQRKELERMRLQHEMEWREMMRLKELKDRNGTEMRTRRLSEANSMTRLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N236</accession>
    <name>A0A9P6N236_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cullin-5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">CUL2</name>
        <name evidence="10" type="ORF">BGZ80_001837</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7 8">Belongs to the cullin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000143">
        <property type="protein sequence ID" value="KAG0021719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N236"/>
    <dbReference type="OrthoDB" id="27073at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031461">
        <property type="term" value="C:cullin-RING ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031625">
        <property type="term" value="F:ubiquitin protein ligase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000014">
        <property type="entry name" value="Cullin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1310.10:FF:000012">
        <property type="entry name" value="Cullin 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1310.10:FF:000014">
        <property type="entry name" value="Cullin 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1310.10">
        <property type="entry name" value="Cullin Repeats"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1030.10">
        <property type="entry name" value="Ring Box Chain A, domain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045093">
        <property type="entry name" value="Cullin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059120">
        <property type="entry name" value="Cullin-like_AB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016157">
        <property type="entry name" value="Cullin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016158">
        <property type="entry name" value="Cullin_homology"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036317">
        <property type="entry name" value="Cullin_homology_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001373">
        <property type="entry name" value="Cullin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019559">
        <property type="entry name" value="Cullin_neddylation_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016159">
        <property type="entry name" value="Cullin_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11932">
        <property type="entry name" value="CULLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00888">
        <property type="entry name" value="Cullin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26557">
        <property type="entry name" value="Cullin_AB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10557">
        <property type="entry name" value="Cullin_Nedd8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00182">
        <property type="entry name" value="CULLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00884">
        <property type="entry name" value="Cullin_Nedd8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75632">
        <property type="entry name" value="Cullin homology domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74788">
        <property type="entry name" value="Cullin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01256">
        <property type="entry name" value="CULLIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50069">
        <property type="entry name" value="CULLIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0832">Ubl conjugation</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Cullin family profile" evidence="9">
        <location>
            <begin position="388"/>
            <end position="619"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00040451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0021719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="746" mass="86231" checksum="AF324B5C2BC16983" modified="2023-09-13" version="1">MSLRRKRIDFNVAFDEFKRDLVKMFEFTGTGVCGMDMFQLIYDICNAQPKPFSERLYCAIADFLCDYATGVRQAILSQDEVVPIYSAYWKKYSIATYYLNYACDYLNSRIVKTRKVAGASEKRPFVGQSNYPRQDVQALANQIWRDHVVMEIKLRKQNRLMYQIFETIRQDREGHQVNSSVVQEAILSLVSLNSKTDHPLELYIDEFETPYISQTKAYYKAESSIKLSSCTISQYMRSAIDRLAQEGIRNSRYCHPTSHARIIQECETQYISEHQKNIQSEFERMIAHEKTDDCTMAYSLLSRIEEGITPLLNTFERYITTVGRDIILGLGPTVSKDPREYVEKLIELHTKYMQMCARVFTNDAAFVAAVDKAFRTIVNDTATNTAARSPEVMARYTDIMLRKKQKTGLSESEIEDRLTRVVILFKYIDDKDLFQKFYSRVLAKRLIFDASMSAEAEANMISRLKNACGVEYTSKLQRMFTDMTISSDLNSGFKEWLQGNDLSNGVDFSILVLTAGSWPVNSTQPLEFQYPEELGKSITNFTTFYDNRHSGRKLSWFWHWCRADVRVNYLDKRYELSLSLYQFAVLAVFNAGNSYTVSEIRDQTKLVEFELIRVVKSLVEANLLTLEDPEANVSLSTVLNLNMNFSNKRTKLKISGGLQADTPQETTATLKAVDEDRRLCIQASIVRIMKSRRVLSHMQLVQEVIEQCKTRFSPSVPMIKKCIEQLLDKQYIERAENSLDRYVYVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3F4</accession>
    <name>A0A9P6N3F4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_000392</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the p23/wos2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000108">
        <property type="protein sequence ID" value="KAG0022369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3F4"/>
    <dbReference type="OrthoDB" id="1564555at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051879">
        <property type="term" value="F:Hsp90 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051131">
        <property type="term" value="P:chaperone-mediated protein complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06465">
        <property type="entry name" value="p23_hB-ind1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.790:FF:000013">
        <property type="entry name" value="Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007052">
        <property type="entry name" value="CS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045250">
        <property type="entry name" value="p23-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22932:SF1">
        <property type="entry name" value="CO-CHAPERONE PROTEIN DAF-41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22932">
        <property type="entry name" value="TELOMERASE-BINDING PROTEIN P23 HSP90 CO-CHAPERONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04969">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51203">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CS" evidence="3">
        <location>
            <begin position="24"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="175"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="128"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="185"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00025733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0022369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="236" mass="25898" checksum="21E0F831FBDDDFDD" modified="2023-09-13" version="1">MSPDRPSDTESNSDILLTSIAFRVDPSLVLWAQRSNVVFVTVNIPDATAPVTNLTEDKLEFTATSDNKHYAVVIEFNQAIDPETSITKSSPRNFFFTLKKKEEKWWSRLTKGPKPNFIKTDFARWKDEDDEDDEVDESSGMDMGGLGMPGMPGASMGGGMGGMGDMDFQKLMASMGQGGQGMPDFGDEQEGDSDDDDVPALEETEATTEANVFPSKSERGYNFSVDVNTRIYANVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3G3</accession>
    <name>A0A9P6N3G3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_009980</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000065">
        <property type="protein sequence ID" value="KAG0023245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3G3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0023245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="89" mass="9519" checksum="6C9D96B3574D6380" modified="2023-09-13" version="1" fragment="single">HVYMGLRSVLSLVLKSIPTEAELHARKKEFGVKSSWLTRLSDAIGASSGVAGLAGRSYETESTTAQTEDLGVLENDIGVQAIRSNLKTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3G4</accession>
    <name>A0A9P6N3G4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_000736</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000116">
        <property type="protein sequence ID" value="KAG0022223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3G4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050562">
        <property type="entry name" value="FAD_mOase_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356:SF2">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356">
        <property type="entry name" value="FAD-DEPENDENT MONOOXYGENASE ASQG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="1"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0022223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="386" mass="43215" checksum="44A6EEFECB6B1F89" modified="2023-09-13" version="1">MLANILEKTNISYEIFEKTKEIKPVGAIITISPTVLPAFEQLGLYEDFLKMSYPVTGTDVRNKDAKLEASITIENFKQLVGYEFAVCQRSKLYDLLLSRVPDNKIHFGKRVVSLLQNKEGVMVRLHDGATVHGDILVGADGAYSAVRQHLYKQLSNMGKLPKSDSKPITKGFFCMAGITNPLDPQKIPDLKDEFCHCDTIIPNDGKYSWNTLTLPGNIISWGTICQLDSETYINEHLRNSEWSPEENEQLIKELLPSGGLGAVNAILDAVVLANCIYEMKIATYDAVTDALNEYREQRYDEAKAQYESSKFSGKVYYGHTMMERAIRHVVVNYMPPSIQSYGVAKAMACRPQVAFLPLIPNRGTTEVIPQKPSAKYFAEQARVATV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N466</accession>
    <name>A0A9P6N466_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein phosphatase</fullName>
            <ecNumber evidence="1">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_009673</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PP2C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="1"/>
    <dbReference type="EMBL" id="JAAAID010000060">
        <property type="protein sequence ID" value="KAG0023361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N466"/>
    <dbReference type="OrthoDB" id="60843at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.40.10:FF:000130">
        <property type="entry name" value="Related to PTC7-type 2C protein phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039123">
        <property type="entry name" value="PPTC7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12320:SF84">
        <property type="entry name" value="PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12320">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13672">
        <property type="entry name" value="PP2C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0464">Manganese</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="3">
        <location>
            <begin position="33"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="349"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="374"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU366020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0023361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="426" mass="45690" checksum="2AF1A0DB184CB271" modified="2023-09-13" version="1">MSFFDQPFQSTRRNYVFAHGASGFAKNPGKVPTLTPEEDRAYHSVQVGEDSYFVRHDALGVADGVGGWSNTTGANPALYSRKLMHYAFLELEKYDNIEEDAFYDYFNVDPVQILEKSYEQSAIDAKKEGLIGSSTACLAILRDDELRIANLGDCGVSVIRHNEFVFRTEEQQHSFNYPYQLGTGSTDHPSDALAFTVKVESGDIVVMGTDGIFDNLFDEDILEEVVRCVSNVNTAPVTSPYGTGKPIPPSTTTGASSTLKSVGGLWSGLASGAAKLASSSTSTIAAIAGKSATSVLESTSTSAEGTVDQSQLYDTPEEVESCADISPIAAAAIAAASYHSASPYTAASSYSSSSSIQRRQKAPEPSVISEALAKRAKSVGEDTRHHGSPFQSRAMQEGLYYQGGKRDDMSVLVAIIKVAEDSPDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N495</accession>
    <name>A0A9P6N495_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Transcriptional regulatory protein sin3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">SIN3_2</name>
        <name evidence="10" type="ORF">BGZ80_010511</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000074">
        <property type="protein sequence ID" value="KAG0023050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033698">
        <property type="term" value="C:Rpd3L complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010628">
        <property type="term" value="P:positive regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1160.11:FF:000001">
        <property type="entry name" value="Paired amphipathic helix protein Sin3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1160.11:FF:000002">
        <property type="entry name" value="Paired amphipathic helix protein SIN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1160.11:FF:000003">
        <property type="entry name" value="Paired amphipathic helix SIN3-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1160.11">
        <property type="entry name" value="Paired amphipathic helix"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013194">
        <property type="entry name" value="HDAC_interact_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003822">
        <property type="entry name" value="PAH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036600">
        <property type="entry name" value="PAH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039774">
        <property type="entry name" value="Sin3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031693">
        <property type="entry name" value="Sin3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12346:SF0">
        <property type="entry name" value="SIN3A, ISOFORM G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12346">
        <property type="entry name" value="SIN3B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02671">
        <property type="entry name" value="PAH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08295">
        <property type="entry name" value="Sin3_corepress"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16879">
        <property type="entry name" value="Sin3a_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00761">
        <property type="entry name" value="HDAC_interact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47762">
        <property type="entry name" value="PAH2 domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51477">
        <property type="entry name" value="PAH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Histone deacetylase interacting" evidence="9">
        <location>
            <begin position="639"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="297"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="431"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="925"/>
            <end position="996"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1359"/>
            <end position="1386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="17"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="37"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="64"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="149"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="164"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="305"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="341"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="448"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="538"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="940"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1363"/>
            <end position="1378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0023050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1386" mass="154603" checksum="EE72CDB1AFF7A844" modified="2023-09-13" version="1">MPAPPPPPEEKSQWARGPGPQQGYSSPSGSMPPHPSASPYSHHLPPVGGPQGPDQHPSNQGGPVLPPPPMNIVGGPPPRSGPPMPSSRPPTSPSLSSVHGTSSHPSAIMPPSSHGPPPSHTPPDARHHHMASSPGPNHMAPSPHPVQPPHGSHSSSHISSSINAPPPPSQQTPPAPGGGSASSSAASNYRPLNVRDALSYLDQVKVQFQDQPDVYNRFLDIMKDFKSQNIDTPGVIERVSTLFKGHPTLISGFNTFLPPGYRIECLSSANEANMIRVTTPSGHTTTQMGGPIVIPERLPPPAPSHYNQPSYHMQQGSGYQPSIPSISQIQLPPVNSPGYMSQQSSQVLGSSSSQNGSNSKKTPVEFNHAINYVHKIKNRFANDPETYKQFLELLQAYQKEMKPITDVYSHVTLLFKNAPDLLDEFKQFLPENGNPPNPDLFDEMMPQPSTPAPPPRSMPVLSTLSNGMAVGDFPSPSSGDLYAKKGGQVAPAPVMQGSSKKKRPPTTTNDRPLPEGVPGSSKKRLKQNHVPEIGGTSPPISASQQTVVTKNPASVEELAFFDRVKKFLGNKQTYNEFLKLLNLFSQDILDRKLLVEKVETFLAPNKELMEWFKAFVGWDGKDEIIENVAAPRDKVDLGSCKRYGESYRLLPKSETMLPCTGRDEMCWEVLNDVWASHPNWSVEGEGFMPHKKNQFEEVLHRCEEERYEFDMNIEANLHTIALLEPIAKQIQSMSLDERARFKLPEGLGGSSKTIYKRIIKKIYDNERGAEVIDALHNNPAIAVPVVLKRLKQKDEEWKKSQRDWNKVWREIDSRNFYKALDHQGFTFKVADKKFITSKALVTEIEALRREQIDRRLVPSVRPRYQFQFEFKDPSLFRDTNNLILSYLDRQNSFVNSDREKMESFIKEFVPQFFCLDNNFMNEDDVTMGEDDTADGSAAKSFDRSGEKSRSAEGVAKQADAQVKMEPKDDAAPAAGPRVPVTADKDQPRTASPSNTWIQVGNYDVKPTSLGAGPTSDDMKRATLNFFGNTTYYCFFRLHQLVYSRLETIKVAASELSKTISERKLINPAAIDLGLQDPEAIEPEQTNDTGDSYAKFLGLIHKVFDGELEQTAFEEQARHIFATKAYIVFTLDKVIAALLKHMHTIVTDQRCNELIAMFVKDRQHEKNSRRQQIIYRMQADAVVGDENLYKIEYAKDEQTMSIQLLSKNDYTLDTAISSEEKWGYYIDSYVLLTPTEGVLPSSFPTFLKRNLPSNIPEEPQQDIVTHSGLEVKICINTYKIFFVNTTEDFFERKGPKVSKEKLQKGRARRLEKMEAWLKTTLEEQESDEASLVSDFQKWLLEGPEDAKQGLSTTVKTIPATAQSPERKVYTTATTEDKDVTMANAEDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4U4</accession>
    <name>A0A9P6N4U4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Acetyl-coenzyme a transporter 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_001318</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000013">
        <property type="protein sequence ID" value="KAG0024561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N4U4"/>
    <dbReference type="OrthoDB" id="6415790at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008521">
        <property type="term" value="F:acetyl-CoA transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035348">
        <property type="term" value="P:acetyl-CoA transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000289">
        <property type="entry name" value="Acetyl-coenzyme A transporter 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024371">
        <property type="entry name" value="AcetylCoA_trans_1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004752">
        <property type="entry name" value="AmpG_permease/AT-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12778:SF9">
        <property type="entry name" value="ACETYL-COENZYME A TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12778">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 33 ACETYL-COA TRANSPORTER -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13000">
        <property type="entry name" value="Acatn"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="62"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="130"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="167"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="241"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="296"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="328"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="359"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="390"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="493"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="26"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0024561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="535" mass="59812" checksum="53485F68C69FE32D" modified="2023-09-13" version="1">MWARKTRGETLLGDEEREELMLTRRGSPSPSPENRTPQHASLATDEKDGTGTAMSAKDSWNFALLVVLYLLQGVPVGLAFGSIPFLLKAKMSYSQIGVFSLAHYPYSMKFLWSPIVDAVYNKELGRRKSWIVPIQLLTGFMFLWLGINIDDWMGQERVNVGSLTTVFFVLIFFSATQDIAVDGWALTLLSKDNVSYASTAQTVGLNSGYFLSFTVFLAFNSPEFSNKYFRSTPQDVGLVPLGGYLKFWSILYFAITLWLVFLKKEERSQTEQNEIDIKSVYKIILRIIRLPHMKSFMIVLLTAKIGFIANSAVTALKLLEKGFSKEDLALAVLIDFPFQIIFGYYAVRWSSGPRPLKPWLWAFCAHLVCCVVAMLIVSSFPQDGVVTSTYFFLVLATTVTTSFTSTVAFVSMGAFMTVIADPVIGGTYMTLLNTLSNFGGTWPRFFVLEAVDYFTISTCSIMDGNGEGFSCTTEPGKTQCQEMGGSCQIHQDGYYYVSTVCVMIGATLLVLYIAPTIRYLESLNPKLWKLPKEES</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N523</accession>
    <name>A0A9P6N523_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_008102</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000043">
        <property type="protein sequence ID" value="KAG0023775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N523"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="291"/>
            <end position="310"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="322"/>
            <end position="341"/>
        </location>
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        </location>
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            <end position="417"/>
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            <begin position="24"/>
            <end position="42"/>
        </location>
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            <begin position="43"/>
            <end position="55"/>
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        <source>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="KAG0023775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="450" mass="48719" checksum="5E8BADD96BDC4765" modified="2023-09-13" version="1">MGACEFLEHSYITSFRSRKRQQYSTSRVSSSSSASFFPRSPSLQEPSSPQVSIPTAESVPAGEDASSPATTLGLTLEESSSSSTEEQVNTSGSSELSEPPSPTVASASTSSSLSCAALEEHVTACTTSNDIDISSVSGSNSGFNHSDMDAHTNRSEPPSPYTTASSADNISMNTNLETMSPSMAFAMGKEMICPLCRYLHKNQPFMNQESDSDVKPVPGQSIANTNLQQRSIQNRHPFSRSPPPTTLHEHPTSGTVFSMMPSLFETSLGHGPAAGTIRTSPGGICLKTSTWLMLYVMPFTISICFLAFVLGKVETMWSKVSCLIGAAICYMVCWALVVAIMNPDHEARDLLERLNQMQRNELSLETQTLQSSPLNENRANSGSDHATTTATTTLNSNPSDTSSPVHPSSLTSEPSPSLWTTWSQHRYVQSIQDKVMDLSRMLDDLPGDWW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N776</accession>
    <name>A0A9P6N776_9FUNG</name>
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        <submittedName>
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        </submittedName>
    </protein>
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        <name evidence="5" type="primary">DCAF7</name>
        <name evidence="5" type="ORF">BGZ80_008890</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
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            <taxon>Fungi incertae sedis</taxon>
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            <taxon>Entomortierella</taxon>
        </lineage>
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    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
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    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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    </dbReference>
    <dbReference type="Pfam" id="PF00400">
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        <property type="match status" value="2"/>
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        <property type="match status" value="1"/>
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        <source>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="KAG0024732.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
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    <sequence length="388" mass="42467" checksum="9C6F894EEA7AEEEA" modified="2023-09-13" version="1">MSSPQTATGPTSFGQGYVPPSSSSPSTTVPVSSSRHVRKEILNYSAPWPVYGLDWSNQPTEREALRLAVGSFIEDGSNKIQIITLQEFAGSDGKDYNPNSMSDWVSIAETNHQQYPVTKIKWEPYKTKANFCAPLTSFDWNTFDPALIVTSSIDTTCTVWNVETQQAKTQLIAHDKEVYDVTFANNNSDIFASVGADGSVRMFDLRALEHSTIIYETTSSIPSVQANNPQVAAQLPAPLLRLSFNKLDPNYLSTFHMDSSSVQILDIRVPGIPISELRGHKGSVNCMAWSPSSSSEIATGSDDHQVFIWEVNQMRNDRGEDHHHHKSSSAGGSSTNTKSSAPASTIRVLHEPYRAANVGGEVNQISWSSASPDWVAVGFGRTVQALRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
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    <name>A0A9P6SRB3_9FUNG</name>
    <protein>
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            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
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                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
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                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
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    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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            <position position="203"/>
        </location>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
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            <dbReference type="EMBL" id="KAF9992764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="203" mass="23005" checksum="8AAFD02C173FD0B2" modified="2023-09-13" version="1" fragment="single">MVGIGKRKRLLKQAASVSATRRRVAIQESSECQYEQGVESESESESDDDWDEDIEYENKKIHSSFLQRMQEAESTQTSHLRGPYSGSSRATQWRRKQRAEALAQSASGTNSITSYFLQEPTVDSEDTYSDTDDEGESPPFATMIDEITAYLANKDIGGQERARLQIVHHYFNVRKDEPKPRIHAAAKLLSTVYGKTPHWARCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SRZ8</accession>
    <name>A0A9P6SRZ8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
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    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
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                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003950">
        <property type="protein sequence ID" value="KAF9994964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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            <end position="57"/>
        </location>
    </feature>
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        </location>
    </feature>
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            <end position="208"/>
        </location>
    </feature>
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        <location>
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        </location>
    </feature>
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            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
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        </location>
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            <begin position="338"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9994964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="364" mass="40194" checksum="4EDA46353242B653" modified="2023-09-13" version="1" fragment="single">MKRFIRLDSEGLEKGKEKISSTESVTNSPRPDSEGVASQNQPGSNQPDNKFSSPLWSASKSRRISLNSQAGINRGTFEVALKREITSHLEVMVEQIQQAKLIAYGKILESLKRHPIAAGLRSPEPPDIVILEDENELDSSDEESQDLDGYEAPPSPLLRYSNRFELTRSPSHASHIIHSPQHSRRSSIRSNYSDPRSVSDQGGNEALDQTSFGQTFENSAQDDDQSYQQEDAELGQSALMIYSPGYPTSAPVTPRRTTIAGTSSVEPNAAHTPNASFSIQSEEDTSFSLWRMSLPPPLDFTKMGYHDPNFLSEATESLPDHDPLLEPTTPTGCDENDQSWLNPKWSTITTPKRNSAVNGEDVGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6STD3</accession>
    <name>A0A9P6STD3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Carnitine O-acetyltransferase mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">CAT2_4</name>
        <name evidence="3" type="ORF">BGZ80_006373</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
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            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the carnitine/choline acetyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003143">
        <property type="protein sequence ID" value="KAG0000393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6STD3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004092">
        <property type="term" value="F:carnitine O-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009437">
        <property type="term" value="P:carnitine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000542">
        <property type="entry name" value="Carn_acyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039551">
        <property type="entry name" value="Cho/carn_acyl_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22589:SF103">
        <property type="entry name" value="CARNITINE O-ACETYL-TRANSFERASE, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22589">
        <property type="entry name" value="CARNITINE O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00755">
        <property type="entry name" value="Carn_acyltransf"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Choline/carnitine acyltransferase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="Choline/carnitine acyltransferase" evidence="2">
        <location>
            <begin position="67"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0000393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="256" mass="28913" checksum="0E6E9D952215EBB2" modified="2023-09-13" version="1">MDGTPTCRLNDYVNTSLALNKIDHGSANVSSNLEAPQKLNFTLNNEVQKAIETSEKNFEELIGQHGLYLAYYKMHGVSRPTYESAQVRKFQHGRTETCRTVSSESVAWVKAMEDPHVSADEKTALFKKALSSHVEYMANAVEGRGVDRHLLGLRLSLKSNEPKPSMFAQDIFSRSCHWNLSTSQLSGELFDGYGWGEVVPDGYGVAYMVNENNLSFNVASRKEMRPEHLHHYLKEAATEMRRLFEQTLLEAPKPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SUB2</accession>
    <name>A0A9P6SUB2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Rsc complex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BGZ80_005916</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002913">
        <property type="protein sequence ID" value="KAG0002776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SUB2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016586">
        <property type="term" value="C:RSC-type complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001025">
        <property type="entry name" value="BAH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043151">
        <property type="entry name" value="BAH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018359">
        <property type="entry name" value="Bromodomain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037382">
        <property type="entry name" value="Rsc/polybromo"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16062:SF19">
        <property type="entry name" value="PROTEIN POLYBROMO-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16062">
        <property type="entry name" value="SWI/SNF-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01426">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00439">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51038">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00633">
        <property type="entry name" value="BROMODOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 8" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="3" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Bromo" evidence="10">
        <location>
            <begin position="44"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="Bromo" evidence="10">
        <location>
            <begin position="184"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="BAH" evidence="11">
        <location>
            <begin position="297"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="451"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="575"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="461"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="594"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0002776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="606" mass="68447" checksum="9EDC4C0628D198C2" modified="2023-09-13" version="1" fragment="single">MPPLRKKTASVKGPASIAQDLSLDNKQEAMAQIIDRLEKLTDKSGRLISELFMELPDREDYPDYYSIIKTPMAINMVKERLNAGEYDDNNIDNFGNDLKTMTTNAKTYNRDGSMVYRDAVTLESYIDVALKALKSDPTQTKKEEASLTLYTHATATETATATIIFSADFCRRVLDTIKTHEDKDGREMAELFMELPDKDDYPDYYDEITAPIAIDMIEKKIERGAYTTLESFEKDMNRMFENAKQYNAEGSGVYLDAEELQHLFWKTIGKNGRGRMTKGKRARKHDNELPEVVQHGEVYRVGDFVHLQNDSNESKPTIGLIFSIWKDEKGIIGLDAVWFLRPEHIVHPYASRFYPSEVVKASGVHEHLVSDILERCFVLQTKDFIRGRPNNWKKGQSIYVCEQRYNDSYKSVSKIKNWASCLPPGHKPGDIQLDMFPHPLVIKKLPSASMMDKTVKRDTSESVSRASTPQGTSSSYASSREATPTPEPPKITTTTTKSNKRKSAQMLQLGSLAQAPNFVEKQVVPPLNSPPPRPTSSLQHRYRCNYSNLTNKQQCAATFVTELDLQQHVATEHAQFLNNANPPPSLRRGRPKKSSTATDVNAASPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SUV6</accession>
    <name>A0A9P6SUV6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_005325</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002632">
        <property type="protein sequence ID" value="KAG0006243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SUV6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17316">
        <property type="entry name" value="MFS_SV2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23511:SF5">
        <property type="entry name" value="MAJOR FACILITATOR-TYPE TRANSPORTER HXNZ-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23511">
        <property type="entry name" value="SYNAPTIC VESICLE GLYCOPROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="56"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="90"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="121"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="143"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="179"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="222"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="370"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="417"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="443"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="468"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="56"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="294"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="296"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0006243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="512" mass="57053" checksum="A63F6785E5A840F8" modified="2023-09-13" version="1" fragment="single">MAGTNNRARQAQHQAIPVRFSPLSTRELSPEEQSAQMSLLDDLMSDIGMGKYQKQLLILCGLGWLADNMWLQCIALILPRVQAQFEIPDQHIGILSSSMFIGTMFGAMFWGVFADAYGRKLAFNFTLTITTIFGIASSFANSFWFLCLLILCLGFGVGGNTPVDGALFLEFTPKKNQYLLTFLSVFFSFGAVAASLLGYVLLPRFSCEDHVEGGCQGQGWRYMLLALGGVTLSMVFGRVILFKLEESPKFLLNHNRHDEAAIVLHRIFEINHGETQSEEFEEHIEILTSRFKQDFSGESSGESSSSDSESGDMESLADHGTARRRPPGHRSRQDATRGKYGMIFQRYQHEWRDKFDTAVGRFRPLLSPKFRLSTILLWIIWGLVAFAYTAFNVFYPKFLQEHGEDGNRSLKLVYQDILIYSIAGVPGSMLATVMVEGRLGRRYTMAVSTLGTALAIFLFATLSNHTAMTIFSAILSLLSTLNYAVLYSYTPEVFPSDIRGTACGAAAAISRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SVS5</accession>
    <name>A0A9P6SVS5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_004665</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002357">
        <property type="protein sequence ID" value="KAG0007428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SVS5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF39">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="6">
        <location>
            <begin position="1"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0007428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="637" mass="71761" checksum="8281EA44714A29AC" modified="2023-09-13" version="1">MGNDIVKANNDVIDSDKDVITAIKYAKASNIAVAVRTGGHQYCGASSTFGDNIQLDLSSTYTDFTWENDDCTLVTTGISYSLRMFNAKLGKKNRFVPHGQCSHVHLGGHVQTGGYGQLGRSFGLLADHIQKFRIITADGEPRWVSRGVDEDKDLFFAVLGGSPGNFGALTHVTLKVYKDEDYPKSRGLRATYYYNRDRLKRLLDVMVEMADDENFPADFDYCVTMLSTYSGDFFAFSPDMDLRQRQLHPELYSENNIPFWPQMIVVYAQWANLDGAGQTYDPTFFNKIKEAADEGILPLLGIQVDDDVHTPMSKLTSDWIFRNVREFDLPFVKHAYMSNSKTLKEDGWTDWVADKIDIIQKGIFDGCKLSVQIQNFGGSNSRFYQNGLDGTTSYSWRDSNICCVLDCFHNDDHISRYTAMGWQKDNDDEVGHEGARFCVEDRRVLWGSHDLNLHNNHQYYYDGNGKYDRLCEIKNRYDPNGVFTPNGFCVGAVPVHRRVSRAAKSIAANLQTRAAARVHVEVPMIAEVGSVFVGGEGSEVVEVSVEEVSVEEVSVDEVSDVSVMPISCRMIDEEVIPDLMPEIVEAIPEPEPEAREQAMFLYAVSQDSEMAAQLMMREAQLEEILIRRGEQSLSREE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWM8</accession>
    <name>A0A9P6SWM8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Replication factor C subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">RFC3</name>
        <name evidence="10" type="ORF">BGZ80_003431</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the activator 1 small subunits family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001904">
        <property type="protein sequence ID" value="KAG0008450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWM8"/>
    <dbReference type="OrthoDB" id="4199794at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031390">
        <property type="term" value="C:Ctf18 RFC-like complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005663">
        <property type="term" value="C:DNA replication factor C complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031391">
        <property type="term" value="C:Elg1 RFC-like complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031389">
        <property type="term" value="C:Rad17 RFC-like complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003689">
        <property type="term" value="F:DNA clamp loader activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006271">
        <property type="term" value="P:DNA strand elongation involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18140">
        <property type="entry name" value="HLD_clamp_RFC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000028">
        <property type="entry name" value="Replication factor C subunit 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.272.10:FF:000004">
        <property type="entry name" value="Replication factor C subunit 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000129">
        <property type="entry name" value="Replication factor C subunit 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.272.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050238">
        <property type="entry name" value="DNA_Rep/Repair_Clamp_Loader"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013748">
        <property type="entry name" value="Rep_factorC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047854">
        <property type="entry name" value="RFC_lid"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001679">
        <property type="entry name" value="PRK00440.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11669">
        <property type="entry name" value="REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11669:SF9">
        <property type="entry name" value="REPLICATION FACTOR C SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08542">
        <property type="entry name" value="Rep_fac_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="post-AAA+ oligomerization domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="9">
        <location>
            <begin position="70"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="13"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00070184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0008450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="357" mass="40255" checksum="E501A6EE4FA72845" modified="2023-09-13" version="1">MDEDQVMADATDAFSSFPPNSKSNGKFGEHNNAADDTLPWVEKYRPVTLDDLVSHKDITSTIERFIDENRLPHMLFYGPPGTGKTSTILACARKLYGPMWKSMTMELNASDDRGIDVVREQIKNFASTKKIFSSGFKLIILDEADMMTQTAQNALRRVVEKYTRNVRFCIICNYVSKIIPALQSRCTRFRFAPLEQSQVDARLDHIVQAENVNITPEGRKALLQLSKGDMRRALNILQACHAGYEVVDEDAVYNCTGNPHPADIETIVNSMLTEDFTTAYSNISYLKTIKGMALQDILTEVYNYLELVDMPSNSRVYLLDKMADVEYKLSTGANEKLQLTSLVGSFRIGAELMQKQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWP9</accession>
    <name>A0A9P6SWP9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NADH:ubiquinone reductase (non-electrogenic)</fullName>
            <ecNumber evidence="2">1.6.5.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">NDE1_1</name>
        <name evidence="13" type="ORF">BGZ80_003368</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>a quinone + NADH + H(+) = a quinol + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:46160"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.6.5.9"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a ubiquinone + NADH + H(+) = a ubiquinol + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:23152"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the NADH dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.6.5.9" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010001888">
        <property type="protein sequence ID" value="KAG0008496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWP9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050136">
        <property type="term" value="F:NADH dehydrogenase (quinone) (non-electrogenic) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045024">
        <property type="entry name" value="NDH-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054585">
        <property type="entry name" value="NDH2-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706:SF47">
        <property type="entry name" value="EXTERNAL NADH-UBIQUINONE OXIDOREDUCTASE 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706">
        <property type="entry name" value="NADH DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22366">
        <property type="entry name" value="NDH2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="11">
        <location>
            <begin position="65"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="domain" description="External alternative NADH-ubiquinone oxidoreductase-like C-terminal" evidence="12">
        <location>
            <begin position="423"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF22366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0008496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="491" mass="54747" checksum="9E3F1528DA9D0B5F" modified="2023-09-13" version="1">MATAGKTAASNTTPTPPPKKGWPRLRALKRLVQLGVIGGIGYTSYVTYTSRHPMEQLPFDPKKRTVVILGTGWGAISFLRKINTDDYNVVAVSPRNYFLFTPLLPSCTVGTIELRSIMEPVRFITRHKSRNVKFYESECTDIDPESKTISITDVSDVKGAVTNTTIPYDYLVVAIGADNQTFGMAGVREFACFLKEIWDAQKIRTRLMDCIESAGFASQTPEEVDRLLHMVVVGGGPTGVEYAAELHDFLKDDLELWYPELADKLKITLVEALPNVLPMFSSQLIQYTERTFKQNKIEVLTKTMVKEVADKEIKVLDADKNIVSIPYGLLVWATGNCPRPLARKMMARLKHTQTSPRGILVDNYMRVAGANDIYAIGDCTFTKYAPTAQVASQQGNYLASVFDNLARIEEGQDKKITPFEYSHQGSLAYIGSDKAIADLPFLNGNVSVGGVATFVFWRSAYISTQFSFRNKFLVMGDWLKSTVFGRDVSRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWT3</accession>
    <name>A0A9P6SWT3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003148</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001815">
        <property type="protein sequence ID" value="KAG0008704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2367179at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="213"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="348"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="759"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="134"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="262"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="355"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="389"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="402"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="418"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="759"/>
            <end position="769"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0008704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1476" mass="163804" checksum="4A5A203FCF6DD108" modified="2023-09-13" version="1">MEPKYQYFRSHSTLVRLRVTENPSTGLCYIFWGDLRVAFPGIARVQDGDVFVPFMRCQREFRLKPFRIEYIPNAVLDIIYKDEANPNISLTASLRASKRKAMEPLPLVDKEGDHDLGERREQDFKGNTFDHLAVSSSGNNVNSTSSVLASPPSVTEFDPSLLSPSPSPSPSPSPIPRTPDSLANELKEHEDGTSSANSSVDLNLDKAMGSIDEPTAARNSHGSSNPTLQVPLESGSEPSNSTLQAPPESRSGSGSESGSGSGTATPSGTSFSSNTDLTSLTNESKLSTVMSLVKGLSLQVAGSGAHKDVQEAAAKHSVKISNLGSIIAGTMRTTETGVMLEPSVCRVEEAGPIDESERTSAKPSHLVEKQSTTHTSQEDDDPSKKDDLGTTSSGVVSLGGAEDPKDTQEAVPRRQHNQLQQQKQPKSTPKQKQQAQKQQQTLTLAQPTALSKSTIGKASVANTTLTASRTQPAAKVNPYSLLTNAMPLLLQSGLFSEYTGSLTGTNGDPRASALVDVITSYQESEELIAFNRMNSRSQRVPYRHAIGKAVNEKDGAASTPGNNSNIDPWTEIGQLLKVFTQAAAKGNLRVADKMGLQLERKLYNLEKKMVTQPELKARVQPVSDSFWESQHKLTPIRNARIQKNARALLEQRLSLTESIVPNMFVVLPASLEANPIQLRVHFLCQCRGETLCRAPVVKGEDEEATPAYFPSHFGHLTSHPGYELVFDQQLVLVGGLFMYDLLEIIKYGVTLEGVYVEQDDDEGEDEENQNDSTLHSDDRRKTKTVIIPPLNPCGSKAEVDIYHRVNYAMEHIIGNRCVETSPGGLRSFLKGLTQEIKLPSRDESLGGLVRVLSSQGSTRWLCDDHYNALHRAPRMSAFVRLIEGQKAVPIFWEYHLGQVQVLFPSRKELKVFLNILKTLRAPIQDLTLMLDWPLTALDLQHLHQSLHAFAVNIPSIRICLGKGSTQEESEAFKQNQDNLIASMLAKPEVHLFLLEDARPLQEEWDASTRLFANHKELNFDNWERYPNTRAVVIKNACGFVKLGIVVESTEAGLELVKRYFGGESAKSRTLMGLQLYANKHDAVKYEFKDGVMTDVCLSATSSSPKKLLQVSNIELLQFKVQTKQDRSELESILKRNSTICEVEVHCSMEIMPEIFTLLKRWRRGHGRPPSVRIEHGETKLWWIQELFNYEPPSLELSVQEPIGLGPILDMVGPELRTFEGPLSDSQAAIFLNSVRKKGSKLTELDLDISYFTPAGYESISKVVEMSRLEMLGVIVSSRTPASMSPGAVSPTMDWPRIAHFILRVRNVSRSLQFIGQDVNEILQNLQPKLDLTQLSTLKKVEIYGGKSVSLDLTKGLPMVLSILTKVSLWTVKFVDIRIDHDSWAQILGAINYQRLIWLDIRQSGFGPDQMACLLEKMPKNSTIKKLYIRMGARPTSKQLQQWRAALAKKTTNLNFLCEMDERAPNEIGMRVRDIRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SX35</accession>
    <name>A0A9P6SX35_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">Arginase</fullName>
            <ecNumber evidence="2 11">3.5.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">CAR1</name>
        <name evidence="12" type="ORF">BGZ80_002763</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-arginine + H2O = urea + L-ornithine</text>
            <dbReference type="Rhea" id="RHEA:20569"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16199"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="EC" id="3.5.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8 11">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="8 11">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Nitrogen metabolism; urea cycle; L-ornithine and urea from L-arginine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9 10">Belongs to the arginase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.3.1" evidence="2 11"/>
    <dbReference type="EMBL" id="JAAAID010001698">
        <property type="protein sequence ID" value="KAG0009070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SX35"/>
    <dbReference type="OrthoDB" id="9992747at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004053">
        <property type="term" value="F:arginase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006525">
        <property type="term" value="P:arginine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09989">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.800.10:FF:000009">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.10">
        <property type="entry name" value="Ureohydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014033">
        <property type="entry name" value="Arginase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006035">
        <property type="entry name" value="Ureohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020855">
        <property type="entry name" value="Ureohydrolase_Mn_BS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01229">
        <property type="entry name" value="rocF_arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43782">
        <property type="entry name" value="ARGINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43782:SF3">
        <property type="entry name" value="ARGINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00491">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036979">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00116">
        <property type="entry name" value="ARGINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01053">
        <property type="entry name" value="ARGINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51409">
        <property type="entry name" value="ARGINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11" id="KW-0056">Arginine metabolism</keyword>
    <keyword evidence="6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 8 11" id="KW-0464">Manganese</keyword>
    <keyword evidence="5 8 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="8">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="237"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR036979-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0009070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="311" mass="33253" checksum="BE9B20A7BA27448F" modified="2023-09-13" version="1">MSVTHKFLKQKSVGVVGVPFSGGQPRDGVDQGPLKIIEFGLLEQLKELDWSVKFDGHRDYTALKPASDPPVGKLLNARYVSAVTESVATAVAAHAKEGSLALTLGGDHSIALGTVSGTMSVHPNAGLIWVDAHADINTPETTESGNIHGCPVSFLLGIAGQIPEFSWVKPCLSPDRIVYIGLRDVDAGEKKILREHGIKAFSMHEVDKYGIAKVVDMAIQHISPNLSRPIHLSFDVDALDPTVAPSTGTPVRGGLTFREGHYICEAIHETGCLVAMDLMEVNPSLEDDQAVFQTVTIGCSLVRCAMGETLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXA4</accession>
    <name>A0A9P6SXA4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Anaphase-promoting complex subunit 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ANAPC5</name>
        <name evidence="9" type="ORF">BGZ80_002893</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the APC5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001739">
        <property type="protein sequence ID" value="KAG0008935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXA4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045842">
        <property type="term" value="P:positive regulation of mitotic metaphase/anaphase transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070979">
        <property type="term" value="P:protein K11-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037679">
        <property type="entry name" value="Apc5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026000">
        <property type="entry name" value="Apc5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12830">
        <property type="entry name" value="ANAPHASE-PROMOTING COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12830:SF9">
        <property type="entry name" value="ANAPHASE-PROMOTING COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12862">
        <property type="entry name" value="ANAPC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0498">Mitosis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Anaphase-promoting complex subunit 5" evidence="8">
        <location>
            <begin position="283"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="491"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="794"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="495"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="794"/>
            <end position="816"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0008935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="854" mass="95300" checksum="02243F0B35492FC6" modified="2023-09-13" version="1">MSGRRPFARTATDISLRPPQAQGFNSSEQGIAAAFANDHLNGTATGQYGFNSGPVHVVSYLTPHKVSVLILIEYYCQCRSPLPSVQNLLLFLLKCIQDPMEYLHDNVNKFGSVVTSEVGSDVWTHVCVTLKRIKSPHHLSDFFLSKLEMDVADPKDIAPQRIGLQDLVIKRGAAPDPESIMGLYVRKARLEFKKLSFEDMCKFYTALETYISAIGKSEQNPESSRQPSITSKNPTVLSSFDVEKYLDHHTQRLSELGQADIPEELLAHVYSIQSRMPSLAKTHYITCLHAQQTGDFEVAIQSLHRFFDYCMAVRDRELYQYALLNLAMLHARFSHFEQALIQGESMPKALGALVKASSINLRHSLDGAGGIVQLFQSKIWGAYGYSSLSSLYSQLQLQYRPSETDMNDAASGYSKTASDLALAGRFEEALRVINLAKTKFPLKTMKATPWIQTLVQILHRRAVSTNQLRDAEIWTQQLGTALVNTSIMASVSDSGDSKSDDGGRVFSRESQLDDTSREVQLEIILQKAILSVLVGQGLSGAHQLSEGLAIVQQNQWPGMHKFTVMYLLALAEIYMDSDSAISAMPLLLTAMTLSEHNLQRPLSLLVKLRLSEVLLYLDSVKQANDLVEGLMSMVLSQGDVYVQSLAYFQRAKCLLARVDKAEPLQTADDTRRNQLKYVIEHLERALEGFQRIESLKDIAQVLYFRVRVFHMLGQADDIENALHLFKASSIKLSSGKNSREPSWFSYYYTRDSFEGILGIKDEKSNPESSGAGTLNKLEGPSKLGQKKAFGFTRTGSSQWSTLRRTPSQLWQSTTASEPAPALPPPDEREEVSGIRSEEESMDIDMADETGRSLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXQ5</accession>
    <name>A0A9P6SXQ5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CRAL-TRIO domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_001816</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001422">
        <property type="protein sequence ID" value="KAG0010071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXQ5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052432">
        <property type="entry name" value="PITP/CRAL-TRIO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46590:SF1">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL TRANSFER PROTEIN CSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46590">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL TRANSFER PROTEIN CSR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="3">
        <location>
            <begin position="136"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="45"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="306"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="54"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0010071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="389" mass="44751" checksum="AD0B0DAAAC09352B" modified="2023-09-13" version="1">MSTYVQPVAPTEGRLGHLTTEQTEKLQNFWIRLYDIFDGKTQFDQTAPSSFKGQNRDDDTPAPAPEKKSGWFGRKEKAAPAVEAAKEAPAARFTGADLHKAFWKLTMMDHPDLIVLKRIDELVELSDVELDKKYPKFIEQMKLGKGYLRGADPLDRPMSVVHTRLHHKSDQPPETIHRFTLYTMECGRMVLPQGAETVIVIFDLSNFGMDNMDWGFVRLFVQCFESYYPETLGVCVVHRAPFVFWGLWKLIQPLLDPVVASKFVFTRNNAELHKVIPRDRLPINHYDGLDDWTYKYVPAAPGENDAMKDLAKKEELLAERHELEAKFDAVTRAWIGNVNGKNSSERDEIAQSLREQYTRLTPYVRSKNLYQRWGVAHDGQVTWTYNVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SY03</accession>
    <name>A0A9P6SY03_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glutamate dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">GLUD1_1</name>
        <name evidence="13" type="ORF">BGZ80_001938</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-glutamate + NAD(+) + H2O = 2-oxoglutarate + NH4(+) + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15133"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.4.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-glutamate + NADP(+) + H2O = 2-oxoglutarate + NH4(+) + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11612"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.4.1.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7 11">Belongs to the Glu/Leu/Phe/Val dehydrogenases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001461">
        <property type="protein sequence ID" value="KAG0009919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SY03"/>
    <dbReference type="OrthoDB" id="6718861at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004352">
        <property type="term" value="F:glutamate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006538">
        <property type="term" value="P:L-glutamate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01076">
        <property type="entry name" value="NAD_bind_1_Glu_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000100">
        <property type="entry name" value="Glutamate dehydrogenase 1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10860">
        <property type="entry name" value="Leucine Dehydrogenase, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006095">
        <property type="entry name" value="Glu/Leu/Phe/Val/Trp_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006096">
        <property type="entry name" value="Glu/Leu/Phe/Val/Trp_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006097">
        <property type="entry name" value="Glu/Leu/Phe/Val/Trp_DH_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033524">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014362">
        <property type="entry name" value="Glu_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033922">
        <property type="entry name" value="NAD_bind_Glu_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11606">
        <property type="entry name" value="GLUTAMATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11606:SF13">
        <property type="entry name" value="GLUTAMATE DEHYDROGENASE 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00208">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02812">
        <property type="entry name" value="ELFV_dehydrog_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000185">
        <property type="entry name" value="Glu_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00082">
        <property type="entry name" value="GLFDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00839">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00074">
        <property type="entry name" value="GLFV_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0520">NAD</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 7 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal" evidence="12">
        <location>
            <begin position="231"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="150"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="277"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="406"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalysis" evidence="10">
        <location>
            <position position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0009919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="514" mass="56017" checksum="A66BB6EB06450801" modified="2023-09-13" version="1">MVAATLLRRTPGTLSSALRLHRATAAVATPFVRSLSTHVTNAACEDYEPGFLGSVETFFDRAARISGISENSLSAIKAVDSVLSVKFPVEIDPDNHVIIEGYRAQHSRHRLPCKGGIRFSDEVDLQEVEALASLMTYKCAVVDVPFGGAKGGVKLNPKKFTPAQLERITRRYTMELCQKNFIGPGIDVPAPDVGTGPREMSWIMDTYRQFNPQDVNAAGCVTGKPISQGGVRGRNEATGLGVYYGVREFLHFPEVQKMSGLTGGIAGKTVIVQGFGNVGYWAAKFFYNNGAKIIGVGEHDVSAYDPNGLDIEALFKHRSEKGSFKGFGNAEIIDEPIKILERECDILIPAALERQIGLKNAKHIKAKIIGEAANGPITPDAHDYLVSQGKVVIPDLLLNAGGVTVSYFEWLKNLSHVRFGRMSRKWEEAGKSKLLTLVEENAGRQLTPQERRAVIHGAEEHELIYSGLEDTMIGACEETRATAALKKTDFRTAALVNAIQKISTVTTQSGQMFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SY73</accession>
    <name>A0A9P6SY73_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ABC1 atypical kinase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_000821</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. ADCK protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001180">
        <property type="protein sequence ID" value="KAG0011253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SY73"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13970">
        <property type="entry name" value="ABC1_ADCK3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034646">
        <property type="entry name" value="ADCK3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051409">
        <property type="entry name" value="Atypical_kinase_ADCK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43851">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43851:SF3">
        <property type="entry name" value="COENZYME Q8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ABC1 atypical kinase-like" evidence="6">
        <location>
            <begin position="407"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="56"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="106"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="243"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="70"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="106"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="138"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="243"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="280"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0011253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="769" mass="84008" checksum="BEAEBF9DA4388271" modified="2023-09-13" version="1">MSARRFADAQALAAVGASVSRKFLALEMKHLKAYAATSSLLKKSSPSFTSAVTAITHDASSSSQRDHQNTSYPSSETSSTSTGSAWIDQILSSATSPLKSVAVQVSQPPVTTTDGSLPSNPSFLTAPVSHGHSGPTITTARSTASASESSKKRETQINRDVLETIRRESKWLDSLPAEDITKLNKGDAELEDRWTQKERLGPRMMVYEPLNQTNEEADTDSGGFEEIKATNAISQKLGVTEMSYSTPSSVTSPQAPESTSSLGQTTASATEVLDTGAIGSTTSSTASTSSASVPPVENSFTEEEIKSASVKKNLSAAPMPTSRIGRLFHYGGLAASLGVGALTETVRRTVGSGTASPDSPTFLTPANMDRLVSKLTKMRGAALKLGQMLSIQDNKLLSPELEEVLLRVQNSANFMPEKQMRKVMSQTMGSNWESEFTDFGMIPIAAASIGQVHRAVHRATGMPVAVKVQYPGVAASIDSDLANLKTLVVMSSILPRGMYLDNTIKVAQRELAWETDYLREAECIEEFGRLLKDDPDYQVPRLVPEASGPMVLTMEWMRGETMTYAMQNCDQASRNRIGTNILSLCLRELFDFQYMQTDPNWTNFLYNPKSTKLELLDFGATRGFDSKFTSLYLKTILAGAAGDREGCLRYSRELGFLTGEETPVMETAHINSLLTLSEPFQESAPDVYDFKYQTITQRVKDQIPTMLKYRLTPPPDETYSMHRKMAGAFLLCSKLGAKVECKKLFREITGRYNESQVDDRRGLNYGRGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SY82</accession>
    <name>A0A9P6SY82_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Vacuolar protein sorting-associated protein 35</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">VPS35</name>
        <name evidence="12" type="ORF">BGZ80_001594</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Plays a role in vesicular protein sorting.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the VPS35 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001366">
        <property type="protein sequence ID" value="KAG0010313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SY82"/>
    <dbReference type="OrthoDB" id="10258141at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030906">
        <property type="term" value="C:retromer, cargo-selective complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.660:FF:000003">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.660">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 35, helical subcomplex Vps35-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005378">
        <property type="entry name" value="Vps35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042491">
        <property type="entry name" value="Vps35_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11099:SF0">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11099">
        <property type="entry name" value="VACUOLAR SORTING PROTEIN 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03635">
        <property type="entry name" value="Vps35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009375">
        <property type="entry name" value="Retromer_Vps35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="309"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="550"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="355"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="552"/>
            <end position="562"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR009375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0010313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="909" mass="102600" checksum="F97AF49F51FBC6A7" modified="2023-09-13" version="1">MATPTAPSAEDQAKFLEDALGVVKIQSFQMKRCLDNNKLMDGLKHCSTMLAELRTSNLTPKNYYELYMAIFDALRHVTTYLKEAHQSGRHHLADLYELVQYAGNIVPRLYLMVTVGSVYMEMPDAPVKEIMRDMMEMARGVQHPTRGLFLRYYLSGQTRNGLPLGTEDGPEGNITDSIQFILTNFIEMNKLWVRLQHQGHSREREKREMERKELRILVGTNLVRLSQLDSVDLNVYQSTILPSVLEQIVSCKDVIAQEYLMEVIIQVFPDDFHLRTLGPLLSATAQLHPKVNVKQIVIALVDRLAAHAAREADSNDDDDVSEAPTPPREPSIKADEAQNEGEATNGEEATKETEGGEEADEEKEKEEKEEEATTEEEQPTPAPKPPKVRKIRGIPEDVKLFEIFWGKIIELVKFRPDLSIQDITALLVSLINLSLSCYPDNLGYADQVLGFAKEKTAEYSESPELQHKDTVTNLQNLLMAPIQHYPSILTLLELPHFNGLLSLQPYQTRRAIAHAVVASILKNDTTIGSPEDVNGILEICAVMVRDQKDGGHNSNPFRSTRGNRGESGSVDPEEFAEEQGKLARIIHLFKSEDADTQAAILSAARKQFGDGGERIRYMFPPLVIQAVKLARRFKKLQDVDEGWEKKCSTLFRFIHQVISILHSKVDNSDVVLRLFLLAGQSADECGFEDICYEFFVQAFTIYEESISESKAQFQAITLMVGTLQTTTCFNVDHYDTLITKCALHGAKLLKKPDQCRAVYTCSHLWWGTMIVGQQEDGTEAVQPYRDGKRVLECLQKALKIADSCMDSVTNVELFVEILNRYIYYFEKQNEAVTVKYLNGLIDLINTNLGNMENPDQHPPSSNSSSLLENDPADISKYVMAHFRNTIYHLERRKNAGDEKYAELDASLAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYP4</accession>
    <name>A0A9P6SYP4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_000098</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001013">
        <property type="protein sequence ID" value="KAG0012255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYP4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0012255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="79" mass="8961" checksum="599F9AB32BC9A8F2" modified="2023-09-13" version="1" fragment="single">IPDLSSNQDSVYMEYFFRSIAIRILSAAGVGPWLYGTEIARQIFPKQPDERASKSTLARLNQGTVLTYIRVYDHRSIPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYQ4</accession>
    <name>A0A9P6SYQ4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="20">Mitochondrial porin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="20" type="primary">POR1_1</name>
        <name evidence="20" type="ORF">BGZ80_000054</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the eukaryotic mitochondrial porin family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the ubiquitin-conjugating enzyme family. UEV subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001003">
        <property type="protein sequence ID" value="KAG0012315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYQ4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000813">
        <property type="term" value="C:ESCRT I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046930">
        <property type="term" value="C:pore complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008308">
        <property type="term" value="F:voltage-gated monoatomic anion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072666">
        <property type="term" value="P:establishment of protein localization to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043162">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07306">
        <property type="entry name" value="Porin3_VDAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11685">
        <property type="entry name" value="UEV_TSG101-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.160.10:FF:000012">
        <property type="entry name" value="Voltage-dependent anion-selective channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="entry name" value="Porin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052070">
        <property type="entry name" value="ESCRT-I_UEV_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037202">
        <property type="entry name" value="ESCRT_assembly_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001925">
        <property type="entry name" value="Porin_Euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027246">
        <property type="entry name" value="Porin_Euk/Tom40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017916">
        <property type="entry name" value="SB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008883">
        <property type="entry name" value="UEV_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23306:SF3">
        <property type="entry name" value="TUMOR SUPPRESSOR PROTEIN 101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23306">
        <property type="entry name" value="TUMOR SUSCEPTIBILITY GENE 101 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01459">
        <property type="entry name" value="Porin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05743">
        <property type="entry name" value="UEV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09454">
        <property type="entry name" value="Vps23_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00185">
        <property type="entry name" value="EUKARYTPORIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140111">
        <property type="entry name" value="Endosomal sorting complex assembly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51312">
        <property type="entry name" value="SB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51322">
        <property type="entry name" value="UEV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0967">Endosome</keyword>
    <keyword evidence="12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="15" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="13" id="KW-0626">Porin</keyword>
    <keyword evidence="10 16" id="KW-0653">Protein transport</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="5 16" id="KW-0813">Transport</keyword>
    <feature type="domain" description="UEV" evidence="19">
        <location>
            <begin position="4"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="SB" evidence="18">
        <location>
            <begin position="309"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="150"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="150"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="189"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="201"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAG0012315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="672" mass="73704" checksum="92278E1C23283AC4" modified="2023-09-13" version="1">MDPEIAEWLQRVLQTIGYQHRERMYADVEAVLRLFLNFLVPKAETYTHDNGRSQLLLSLIGTIPIVYQSATYNIPVALWLPTSYPSVAPIIFVTPTAQMLVKAGKYVDISGRCYHPYLAYWSNKSDSNLVEIISIMQGVFSQEPPVYAKSNVSAQPQQQSSPTLGGSYPSPTTSLKPAPPILTYSPRTSSSSAISPQSQQNRYPTPTFGSSSQQLTPQQAQLYTKLQTALLEFNTASSREMQNLVTVNKQLNDAETRTKSELQSLKDLNAKIQYNITTLTGSIEQLNTKIEQIRTWPEKPVDEIICGSSVVHNQLFELVAEEIAIEDTIYYLGKALTQDKVELNAYMKHLRNLSREQFMKKALIKKVKAQLGHIFSIVKMATSIPVPFSDLGKSANDLLGKDFPVGHTKLELKTVAPNGVTFNVLGSQDTKSGHVHGELKTKYVDFKNGLTVTESWTTGNLLTTQIELENKVAKGLKLDITGGFLPSEGKKNAKVGVHYKQLGFNSRAHLDLFKGPTFTGDVVVGREGFLVGGDFSYDVGGSYITRFAAAAGYTAPEYSVAVHAHNSFKVFSASYYHRINADLEAGAKAVWDSKAIPSADKSKAPVALEVGAKLYLDRDAFVKAKVNNAGVVGLGYTQALRKGVKVSVGGLVDTTKLDQAAHKVGISFVFDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T071</accession>
    <name>A0A9P6T071_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">PIG-P domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_010013</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000653">
        <property type="protein sequence ID" value="KAG0015169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T071"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052263">
        <property type="entry name" value="GPI_Anchor_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013717">
        <property type="entry name" value="PIG-P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46346">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46346:SF1">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08510">
        <property type="entry name" value="PIG-P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="25"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="domain" description="PIG-P" evidence="6">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0015169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="68" mass="7985" checksum="7C2F3A3F26172407" modified="2023-09-13" version="1">MYLGWAYLPKEVLDSMGITYYPSKYWSLALPIWLFVLVIYLYVAFFAINLYNTEPFDSFLTITGKSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0D9</accession>
    <name>A0A9P6T0D9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cas12f1-like TNB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_009933</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000640">
        <property type="protein sequence ID" value="KAG0015309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0D9"/>
    <dbReference type="OrthoDB" id="2433906at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046349">
        <property type="entry name" value="C1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Cas12f1-like_TNB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07282">
        <property type="entry name" value="Cas12f1-like_TNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57889">
        <property type="entry name" value="Cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cas12f1-like TNB" evidence="3">
        <location>
            <begin position="36"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="122"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="122"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0015309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="145" mass="16443" checksum="D8E21083B24D8D8E" modified="2023-09-13" version="1">MAVIGIGLGKFSSMSRLSTLHESFLSYFVPLARSLDYIVIGVNEYYSSKKCPVCEEFVAQVAIRRLYCSHCGVYMHRDIMAADNMCRIVQSYLLQQRRPRYLQPVDEKGHYPWEEDCDYVSENSVASTTSPSQETQLAADPALAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0L3</accession>
    <name>A0A9P6T0L3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Carboxypeptidase Y-deficient</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PEP7_2</name>
        <name evidence="3" type="ORF">BGZ80_009627</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000594">
        <property type="protein sequence ID" value="KAG0015793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0L3"/>
    <dbReference type="OrthoDB" id="166134at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="20"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0015793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="238" mass="25968" checksum="19B031784F1A3305" modified="2023-09-13" version="1" fragment="single">MATTNAAGASQLHARAASTPQQQQLQQPHLQQPQRSVTISRRQFGPAPATARPQSNFLSSSPTPTNTSERRPTPPPKSPQSRPVPTSNGNVPNGSPVASVDCPICNISLRNLAQLNQHLDTIHPEEPDDVKSAVSQFFKNAQKVLNPIAKNATTTLKNIPANSSELLRKIQDLDLDTATSGNSLSRPPPSGGFIGWTDPRADAIVTKRHWVRESDNDECYQFNCEKGLGIRYGRQHCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0R0</accession>
    <name>A0A9P6T0R0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SWR1-complex protein 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">CFDP1</name>
        <name evidence="5" type="ORF">BGZ80_009313</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SWC5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000545">
        <property type="protein sequence ID" value="KAG0016291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0R0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000812">
        <property type="term" value="C:Swr1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011421">
        <property type="entry name" value="BCNT-C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027124">
        <property type="entry name" value="Swc5/CFDP1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48407">
        <property type="entry name" value="CRANIOFACIAL DEVELOPMENT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48407:SF1">
        <property type="entry name" value="CRANIOFACIAL DEVELOPMENT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07572">
        <property type="entry name" value="BCNT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51279">
        <property type="entry name" value="BCNT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BCNT-C" evidence="4">
        <location>
            <begin position="266"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="100"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="17"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="67"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="117"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="152"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="169"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="189"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="208"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="220"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0016291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="343" mass="37436" checksum="56FCAFF99B42DE98" modified="2023-09-13" version="1">MTKPVVEKKPLNPPVDSDSDSSDDEDYSDVEEDSGDSDTEQNNNDYDGEYDFSSTRSGKRRGAGGSEDTHKKHPLEDTINQAEALRKKSKIDALWAELNTPISKPNSRPELLTAAVSSSTSGSKPEASSSSKMVTITTTYDFAGETITVTKDVPEDSKEAKEFTRKNKGANTSLASQDVTEKSRSDQASSSISISSTTKPMSPSPSTANDSAPSTDTNLTPDPSDSAATSTPSSESATATISTNSGGSRPSMLDSLAQKSKPVRYVRKKSILDELAATYGVKKPPKMNTLEKSKLDWKNFVGKEGIDDELKHHNKDGYMEKVAFLQRTDEHRDREYQMLKKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T174</accession>
    <name>A0A9P6T174_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_008372</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000451">
        <property type="protein sequence ID" value="KAG0017352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T174"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24296">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="455"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0017352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="514" mass="58313" checksum="F139412FEBB329DC" modified="2023-09-13" version="1">MSALATFFELLLKYRTRSNAYKILLAIAIYYVYKYRSHAIGTRPRPDLKEPKGALPLIGHLGMLASVKLTEIHQLVEKQYNDLGPVWSLSLPGFGRMIQIDRPENIEHVLKTNFSNYGKGQAFVNIVSEFVGSGIFTADGAKWKFQRQLASNIFKIKAFSEYTSNVFVVIGKKLTDILGRAADEGTVIDLQKLFLHFTLDAFGAVSYGESFGCLDNIDQVVPFAEAIDDAFDICFKRAHDPLWKIKERLNGVSKRAERNKQILRNYAQDIMNKRRREGYHGEKKDLLQLLMEGEDEEGNPLSDDFIIDGIITFTIGGRDTTALALTWMFYLLLRDGADPENMEKLFQEVDDVVQGSHPTYETHKKQKYAEACFHEALRVFPIVPRNIRCCEKDDILPDGTKVYAGEWVTWSTYAMGRSELVWGPDAKEYKPSRWINTEKPSQSKFNSFHAGPRVCLGQQFATIEALTIIAMVLQSFNLELEDPFRVPTYKPSLIFPMDGGLNVRVSRRSGATAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1F0</accession>
    <name>A0A9P6T1F0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_008158</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000434">
        <property type="protein sequence ID" value="KAG0017570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1F0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="87"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="145"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="257"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="305"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="379"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="214"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="91"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="182"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="257"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="305"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="342"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="417"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0017570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="452" mass="48274" checksum="197564013F5BEBDD" modified="2023-09-13" version="1" fragment="single">MSKHVFPPWHGLVQKILFGLAVILCIALPVSYGTADDHGISSTAVIAVLVSYFVLWALFSLFVRFGMKSYNVESKLPIHTPTPAPPVLLHSPANRNAAPSASAIKSTSPHSDPSDDQYDVEDANRDSEFLRHQSASQKSLRFVDNHNRHQYPPSPATPSSSPMSAGPRQTLPPTSGELGRRGSNSNVKFASQPTSLEESYPTYASYRRAQHTSFDKFTERIRKALETAKAQQRELQEQQEKQQQEQLEQGHLKIEGDTQNDQATGTDSNLLGPPSTVKAGRPRSSSAASMISSLSEKLRLGSGFLGRAGRSRAGSNASATAPPPTSGASVSTPGSRLSFSGPAPSALSVPEPSVSLSSTTTMAAIASAAAVATAMSLPRHPETLSNSDNPKPTHPLAQTLHIQDDSQEGSVVVSLDMPKEPVDREVDSYPEHLPGHTPADSVSNDDGIHVLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1X5</accession>
    <name>A0A9P6T1X5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006103</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000300">
        <property type="protein sequence ID" value="KAG0019249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1X5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="306"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="311"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0019249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="356" mass="40445" checksum="F454D59F26F66AC9" modified="2023-09-13" version="1">MVSLGSLTFAWASLESNSMRWWELSKSDNKLPASLKMILPTPPTEPPLPLVPLEHLSLWSYWAPITEEIDDIFMAFSKTLITLIIRDANLFDTNALSSPLLTEDDPKIVFGNVTSRSPSKLRKLIVILPKQEISLPLHRATSYPDLEYLEMEDGVSRHSCDSALPIGSASNWDLVKSKILANKSIKLLGRPRTMLSTKDSIPYSQSEEILRYEFDSMDQKTMGFRDRADDNRLFIEAIARGEGIRPERLGQSGSKRPYWSWDWSLPNLQTLQLTGEFARRFKFKMLAGCPNLENLVLNMATVGDNDMVTEPEDRQDGDQSETRQGQPAFEHQRNIQVRDFLLPTDGDETHDLGNFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2C4</accession>
    <name>A0A9P6T2C4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNase III domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_005115</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000254">
        <property type="protein sequence ID" value="KAG0019897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2C4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004525">
        <property type="term" value="F:ribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00593">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1520.10">
        <property type="entry name" value="Ribonuclease III domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000999">
        <property type="entry name" value="RNase_III_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036389">
        <property type="entry name" value="RNase_III_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14950">
        <property type="entry name" value="DICER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14950:SF37">
        <property type="entry name" value="ENDORIBONUCLEASE DICER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00636">
        <property type="entry name" value="Ribonuclease_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00535">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69065">
        <property type="entry name" value="RNase III domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00517">
        <property type="entry name" value="RNASE_3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50142">
        <property type="entry name" value="RNASE_3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase III" evidence="2">
        <location>
            <begin position="193"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0019897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="363" mass="40951" checksum="693FA58CFDFDEE07" modified="2023-09-13" version="1">MKRPASQYIEPSNARRPRLLRVQDSNPIEDAFHEEEQVWVEKQNALLALDAGPPDLYACFLSAISLVRRNFSETDHVETKTGLKFRATLDLDEGKLTKRRIDKLYIGHIYSCAGDLAVGTFLSKGSRSACCVMRFVKKTVACAYYRGGLRLALAVTSGIIGPMVGIAAWGDFALKYHQPPIPRTYMRFSNLELSKIEGTLGYNFGEKAVLVESLVHGSFPGELNVNFNYERLEFLGDAVLEFLAALYFLERNQQISDQKLSKVTSHSTSNAALGALCIELKYHSHLRHRKLEQHIAQGIQAFSSKKPWPCYWVRLSIPKVCFADIIESAFGAVFLNSGFDLEAPRDVFDKIVRPFYNKNFIRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2N5</accession>
    <name>A0A9P6T2N5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004202</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000217">
        <property type="protein sequence ID" value="KAG0020426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2N5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="138"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="220"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0020426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="259" mass="29377" checksum="53CA7317A2A6F858" modified="2023-09-13" version="1">MSGIEVEGIQIDQPRQLTDRQLSSLVSLWRLSHYKQAPLSTWSILYSRRRPRRSRGPILCFDTKTYEILRQQREDDFKKKQLHQHQIWQHVQDRLAEQSRILEQEKTEKAKTKAQGNEELQFPPVETAIKTNVSDLASPDLSPTSSYSSSPTITSGSCSPELNPTKRSIRWGLHNNMTKRFDKTSPITLVTVPATDKLPGKSALKVRTAHTIQKQPPKSTKTTTTTTTTTTTTITTTNTANTTAPNNNHPPRKRAVDFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2U6</accession>
    <name>A0A9P6T2U6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003188</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000183">
        <property type="protein sequence ID" value="KAG0021026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2U6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="9"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0021026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="238" mass="26364" checksum="1083F7C92E2A098F" modified="2023-09-13" version="1">MMANGAWGPPLDTDSSSDDSSPGQSPMQENPAIECVSDEDTMLGNSIGCGISCGSECGSEAIGYAYSRHQINYKISKWKETLESASVPIAIPNKLRYKRDAVIDGMELLNINALPLPRNFDRHEGMGAMGNPDNCDEDENLDECLPELSMTFVDPEKSHFEELLYWLYTGDNSRWLRFFAPENYGSILENIRLLNISATDAVDVCLLYESKTSPHMGLKGMAQAILCEPQADDDNMDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2Z9</accession>
    <name>A0A9P6T2Z9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 13">Cytidine deaminase</fullName>
            <ecNumber evidence="4 13">3.5.4.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 13">Cytidine aminohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BGZ80_002932</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 13">This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>2'-deoxycytidine + H2O + H(+) = 2'-deoxyuridine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:13433"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15698"/>
            <dbReference type="ChEBI" id="CHEBI:16450"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 13">
            <text>cytidine + H2O + H(+) = uridine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:16069"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16704"/>
            <dbReference type="ChEBI" id="CHEBI:17562"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 12 13">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the cytidine and deoxycytidylate deaminase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.5" evidence="4 13"/>
    <dbReference type="EMBL" id="JAAAID010000175">
        <property type="protein sequence ID" value="KAG0021170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2Z9"/>
    <dbReference type="OrthoDB" id="414540at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004126">
        <property type="term" value="F:cytidine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055086">
        <property type="term" value="P:nucleobase-containing small molecule metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072527">
        <property type="term" value="P:pyrimidine-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01283">
        <property type="entry name" value="cytidine_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.140.10:FF:000008">
        <property type="entry name" value="Cytidine deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050202">
        <property type="entry name" value="Cyt/Deoxycyt_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006262">
        <property type="entry name" value="Cyt_deam_tetra"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01354">
        <property type="entry name" value="cyt_deam_tetra"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004064">
        <property type="entry name" value="PRK05578.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11644">
        <property type="entry name" value="CYTIDINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11644:SF2">
        <property type="entry name" value="CYTIDINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 12 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 12 13" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="14">
        <location>
            <begin position="14"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10">
        <location>
            <position position="68"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="55"/>
            <end position="61"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR606262-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR606262-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR606262-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU364006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0021170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="151" mass="16586" checksum="6E2CFFB3B3F85CB0" modified="2023-09-13" version="1">MSVSALSVSALSDSQIEDLITQSLAARENSYSPYSKFRVGAALRTTDGKVFQGCNVENASYGGAICAERTAFVKAVSEGHRRFVAIAVSCDFNSFITPCGICRQFMNEFGKSLEIFFVNDDRTYKRAILEDLLPFAFGPEDLPDNSEKQKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3V2</accession>
    <name>A0A9P6T3V2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="1">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">USP33</name>
        <name evidence="5" type="ORF">BGZ80_010727</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="1"/>
    <dbReference type="EMBL" id="JAAAID010000078">
        <property type="protein sequence ID" value="KAG0022961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3V2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02674">
        <property type="entry name" value="Peptidase_C19R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2230.10">
        <property type="entry name" value="DUSP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035927">
        <property type="entry name" value="DUSP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006615">
        <property type="entry name" value="Pept_C19_DUSP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050185">
        <property type="entry name" value="Ub_carboxyl-term_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646:SF86">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06337">
        <property type="entry name" value="DUSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00695">
        <property type="entry name" value="DUSP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143791">
        <property type="entry name" value="DUSP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51283">
        <property type="entry name" value="DUSP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="USP" evidence="3">
        <location>
            <begin position="23"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="DUSP" evidence="4">
        <location>
            <begin position="398"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="domain" description="DUSP" evidence="4">
        <location>
            <begin position="513"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="87"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="618"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="688"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="89"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="108"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="135"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="693"/>
            <end position="704"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU366025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0022961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="715" mass="81440" checksum="554668C50D4D3627" modified="2023-09-13" version="1">MQGKKSKQDGDGTIQDLDLPGLVGLKNLGNTCYMNAALQALSHTAIYSPGHLVSDVKKCNDIFQGSSQQDSQEFLRCIMDKLHEELTYPRTSPDPNSSLPDWRLGKSGSVQLPSVTTTNSTLKGSPKSASNKNGAGSSISSRSSTSSRSAMSSGNSSMSENIEITPARATAPSIISDIFEGTLESRVRCLVCRKQYIKEDKFFDLSIPIDKKTKIIDDTVDDRNGGKDKDGGMLGSFVESIGGNKSIKLQDCLASFCATEELTGEDRYRCTQCDALNDCRKTFRITQLPETLCIHLKRFRYDTYSSKINTYVQFPLDDLDMTPFFKSNDPNELRNTKYELYAMVRHRGVVGGGHYIGYAKHVADNSWYEFDDTYVTKKSASDVAKMEAYILFYRRKSLHREEDRARISRFMSKPKMQIYDSALMVYISRLWFCRWQYFANPGPISNHDFLCPHGGINVTTTRNVMDMVMPIPKVAWDALVDMYGTDGSPIVNISSLESEAEMACEICQREEIALNERRKREHEDVSRLDSNEIGHGQLWYLIGADWLKEWHAFKVGDKPPGPIRNSQFLKDNGQPRAGMKRGVDYRGINFDVWNYLHNIYGGGPEFIRATLDLYAPDPRTLPPSPARDNRSSLQSHHHQLHYLNQQQQLQHQQRPQDYIYQSYSQPHQLQNHYHHQHQHQHQYQPYNYHSHKYQNGNTRKQGPTDSFPPVKTVIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3Y8</accession>
    <name>A0A9P6T3Y8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_010226</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000069">
        <property type="protein sequence ID" value="KAG0023166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3Y8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="274"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="639"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="742"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="788"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="16"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="32"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="48"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="276"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="651"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="772"/>
            <end position="784"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0023166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="900" mass="105589" checksum="E8C869AA685585DD" modified="2023-09-13" version="1">MDQKARQRQIDIQKDFSGQQGRTSPAVTSNKSTDKAIRPDDSLRMGSFKSQRSSSPHISFQDSMSPRASPTLRDRVASSSKSSHSRDGGSRGTSSRKYLQRALSVPIFISNPRGVVPTPSPDVSLELIHSSSRNRDRLSLSAQERMRRYEAQLDQRNEAVMANNQRLMELKQFLESQSQALVIRAQDDYDDDYDDDDEEWKEEQAERAREKAQLAEANVLLEESQILQQQLRKDLEQEQESNKDLESQIQDMSARLKELLELREAQAVELKQVRQQADRDRERWERQLSEERHNQDQLQKTMATSLSNKEKELAEETAKLRVVSQAEVLKLTSNVTSLNQRIQELEGDLRRQDDMTRAAVSKQADQAEEYQSRIQKLEKQLADEQDRLSEDQEARARVRLRVNELAQSVEQKEDEVHELRGMVEERDELLDRRQAELDDALSLAHTLEDQLREQQAESEDIQRREQEKHVKELRQHRGELREMKHKLAAEKESNRKLENRIQILLESQESNQINETKIQQLEEELEKRTLQLSQLNSTSSSTTSTIHQLQGQIEDQERTLLEKDDRIQELEEELKLVQQQAQKVVADLERDVEDARMELKELEQQLNHKDQEFSHELNQRHNQEQLLLERLLNDMESTQLPDEQDDRHQDNQFANDSDSADGSVQYFYSRLQEKIRELRQERLRQSHDLAEMRQQLNQYNAEIDAQQEQLLRVENDRKSLEEQLVQLQDDFAAAEHNQHQLRQQLQKKEQDIRQGRSIPKTLSSSTSHKKQQQQQQQHWYSSDSNQDTEALESQVLELKEQVSILEKEKEELMKRLDYIQTQLQTKEETIQDQSEAAKSIQTKYMERMEALKAERTKLRKTVVRQEGQLFLYLSVIEKLKLEKQKLEKRLTTEGELAPAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T449</accession>
    <name>A0A9P6T449_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Glycosyltransferase family 71 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BGZ80_009101</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MNN1/MNT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000052">
        <property type="protein sequence ID" value="KAG0023542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T449"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000033">
        <property type="term" value="F:alpha-1,3-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006493">
        <property type="term" value="P:protein O-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022751">
        <property type="entry name" value="Alpha_mannosyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31392">
        <property type="entry name" value="ALPHA-1,3-MANNOSYLTRANSFERASE MNN1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31392:SF1">
        <property type="entry name" value="ALPHA-1,3-MANNOSYLTRANSFERASE MNN1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11051">
        <property type="entry name" value="Mannosyl_trans3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="17"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="445"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="445"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0023542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="594" mass="67552" checksum="61E1BBCDAE7037E7" modified="2023-09-13" version="1">MSVSAVLTSSLRKGQNLRIIVVVIIFFFLASISQYQVSFEFSIDSDGQVQSVPSAGEHDIYYTHHIATYNPKDIKPWTKGDTRALETLEGQEVAAFLTAAPSVKTVSSTGQPELVDNAFLHLTKRLRVFRSLWTSLKDYYDQLEDESQQNRFYDQPQPSIAPAVELFQKMERSLFPWILKNHHTSYDLYFETTKATRPADSGQGTTKNRGIVMCVGDKHSVYARTTVKVLREVLQSKLPIEIYYAGDQDLSKENREWFEQFQDLVLVDITKKLDQDMLQISGPIIKPFAMLVSQFQEVILMDADAYFLQDPAILFEDGGYKEVGTVFFYDRTVPKKIAGVNKRAWLDSFLPSVSNHPSKTRWFRFKGDQDQDSGVVVLDKSVHFLGLLAICKMNDVLERNQATYRATWGEKESFWIGMEMIQERYSFVRFGGGVIGDLGDAVPYKQDDKSSNPADSKDDGSSSSLTALSSSSLVRRDRVCGNQLHFNYKGQPLWWNSGLVRDKSTDNSPYLKYTAWIRDEHGIWDIEHSCLVQTFHGALMEVEWNQRQTIYEMLRLDRAVAEELNQPKVKNILAIPRLVKAEGAKGGKGNNEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T4A3</accession>
    <name>A0A9P6T4A3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Acyl-coenzyme A oxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">ACOX2</name>
        <name evidence="18" type="ORF">BGZ80_008107</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2,3-saturated acyl-CoA + O2 = a (2E)-enoyl-CoA + H2O2</text>
            <dbReference type="Rhea" id="RHEA:38959"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:58856"/>
            <dbReference type="ChEBI" id="CHEBI:65111"/>
            <dbReference type="EC" id="1.3.3.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Lipid metabolism; peroxisomal fatty acid beta-oxidation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 12">Belongs to the acyl-CoA oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000043">
        <property type="protein sequence ID" value="KAG0023780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T4A3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003997">
        <property type="term" value="F:acyl-CoA oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005504">
        <property type="term" value="F:fatty acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033540">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA oxidase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055088">
        <property type="term" value="P:lipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.540.10:FF:000006">
        <property type="entry name" value="Acyl-coenzyme A oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.10:FF:000013">
        <property type="entry name" value="Acyl-coenzyme A oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.10:FF:000015">
        <property type="entry name" value="Acyl-coenzyme A oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.110.10:FF:000003">
        <property type="entry name" value="Acyl-coenzyme A oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055060">
        <property type="entry name" value="ACOX_C_alpha1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029320">
        <property type="entry name" value="Acyl-CoA_ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012258">
        <property type="entry name" value="Acyl-CoA_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002655">
        <property type="entry name" value="Acyl-CoA_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10909">
        <property type="entry name" value="ELECTRON TRANSPORT OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10909:SF250">
        <property type="entry name" value="PEROXISOMAL ACYL-COENZYME A OXIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01756">
        <property type="entry name" value="ACOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22924">
        <property type="entry name" value="ACOX_C_alpha1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14749">
        <property type="entry name" value="Acyl-CoA_ox_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000168">
        <property type="entry name" value="Acyl-CoA_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12 14" id="KW-0274">FAD</keyword>
    <keyword evidence="8" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="6 12" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-coenzyme A oxidase N-terminal" evidence="16">
        <location>
            <begin position="23"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase C-alpha1" evidence="17">
        <location>
            <begin position="279"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase C-terminal" evidence="15">
        <location>
            <begin position="487"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="13">
        <location>
            <position position="426"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR000168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR000168-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR000168-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF01756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF14749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF22924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAG0023780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="687" mass="78045" checksum="6018B452E7A0653C" modified="2023-09-13" version="1">MPSTENQQQLDIATERAKCTFNPASFTPLFYGGEDRMRRLRKIEAMIDNDPVFDRSDRYFLGRTERFKRALAMVKRYVELRNEYGFTPDESAYFKVYVDDYIPVHLHESMFLPVLRAQASEEQAKKWIPLAENYHYIGCYAQTELGHGSALSRLETIATLDIERDEWVINSPTQSSAKYWIGTLGKMANHAVVQAKLIINGKDYGAHPFLVPIRSLKDHTLLPGVFIKDMGPKQGAISMDNGYARFDHVRIPRENMLMRFSQVSRDGVYSKPIHPKLAYGGMTAVRTTLINHSALSMARGATIAIRYCAVRRQGNVNVATNLESQVLDYPGVQYRVLPLLSHAFATIFSGYWMNEMYAQYNADITKGDTSLLKDVHVYSSGLKSYCTKLGADGIEEARRCLGGHGFSLFSGMIDFHRQFLATVTYEGENALLTQQVSRYLLKLYKDVIRNPNVKLSPPSKYIFSLVDRNAFVSERCQARSLQDFYKIEVILAALHHRAARLIYELAQAEKSGTDWPQLNLECMRLSKAHVQYILVENFYNGIRKRYNSSPSASPEERNLFLAVESVYNLHVFYTIEVELSEFLEDGYFSPEQASWIHEGVKRCLQAVRPNAVGFSDCFGFTDSFLNSALGSYDGRAYERLAELAEGEPLNSKEMMENGVIWGYEQYLKPLIYGEAGPYKGGNGTSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T4J9</accession>
    <name>A0A9P6T4J9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ef hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_004531</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000023">
        <property type="protein sequence ID" value="KAG0024291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T4J9"/>
    <dbReference type="OrthoDB" id="524326at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00052">
        <property type="entry name" value="EH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000261">
        <property type="entry name" value="EH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11216:SF170">
        <property type="entry name" value="DYNAMIN ASSOCIATED PROTEIN 160, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11216">
        <property type="entry name" value="EH DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12763">
        <property type="entry name" value="EH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00627">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00027">
        <property type="entry name" value="EH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50031">
        <property type="entry name" value="EH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="25"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="domain" description="EH" evidence="4">
        <location>
            <begin position="26"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="EH" evidence="4">
        <location>
            <begin position="145"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="EH" evidence="4">
        <location>
            <begin position="313"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="346"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="3">
        <location>
            <begin position="1235"/>
            <end position="1274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="435"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="635"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="953"/>
            <end position="1061"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1189"/>
            <end position="1234"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="458"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="712"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="735"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="804"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="973"/>
            <end position="985"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="990"/>
            <end position="1036"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1039"/>
            <end position="1061"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1189"/>
            <end position="1201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1202"/>
            <end position="1220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0024291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1276" mass="134001" checksum="6EEAAB20FAE6BE11" modified="2023-09-13" version="1">MASFGGPITRDTGTIRRRDITLSAREKQLYGQLWAAADRDNNGFITGADAVPFFGKSGLSPQVLGEIWVLADADNKGVLGQQGFSIALKLIAHAQNGKTPSAALLDTDAPLPHFEGISPGSPVATNLSPIAAQNTGSEPTLTNEDKNKYGGMFIACGPVGGLLDGEKAREVFLKSKLSVDKLSQIWSLADTKQRGSLDITDFTIAMYYIQHTMDGSIKNLPAVLPPSVLKACTGSITGTGLVSSPIMAAQTLNRQATGNNINIHNPTITRQMTGSITAGLTSSPLARQNTGGTSSLFGGSSSSDIPWDVTPEEKAKFDRFFDQLDKNGTGVVGGEEAGKFFLNSRLPETVLAQIWDLADITGSGSLSKDEFAVAMLLINRKNATGAPIPKTLPPSLVPPSLRNRVTSSMAFSQEPIRAMTGTTAQLRRQSFDLLGDGPTLTASPSAAGASHAEKDLISEDLKNKITSETGELASMQNQINNLTNVTGDLQAKRAMLEKNLHVLSAQKQDISIRLNQIKTLHESESRVIKETESAIAVIQPQLIKLREELQVSEQNLSVARANKDEFLLSLAKDQEESNQIKARLQMNNEEIFKLREELEAKKKDTGRQKGLLEIARRQLESSEAEKQKLINEIAQETDKASLATKEVQTRSPAPPAPHKAAAWDSPSPQPPAPRGTRKEPPPPPASRGTNSSFASRATPEVEEAFGIPEALRSPTGSSHSTSSHRSGAPQALVGASQQSTGSTPFDTIAKQTTGSSPFDSIPKQTTGSSPFDSIPKQATGPSPFDSIPKQTTGSSPFEGVPKQGTGSSPFESVEQQSTAPIAGDSSAFFSAQDDLWSSKTQVLGGQAPVAASPNPETPFMIQQKSMSAVEEDPFGSAFPSLNAPIDTKVDFDSAFQGFSTSKSSQGFGVDSVKSAEAFAEAFPDIDAVGGSDEDKSKRVSAFGFEDDFSVTPFSASLEKSKEDDEFPPIVEVAQDESDDSDDENEEKFVQASSNFTGTPDPFQTSAASESGAPTQPIASPSEEPFSTPSNIASPAPTNVPGSSSEPVAPVAPTAVAPTGSATKKLTAADFSEFETSFGGSNDDFDSAFKGVELSASKVSGDTASKISGFDDAFDSFNPSFDDAFGPSSSPFGTTGSQAPAATAASSNAFGTVDLDAAFGGFGVSGNTAGTGAQNNGFDDGFKDFEAQFASSSGQTAPTEVSPTPAAQPSTGGATAPAAPADKIDSTATSAPVPPAVELRGVDELINMGFTRKQAEDALLRYDNVERAANFLLEGGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T4N3</accession>
    <name>A0A9P6T4N3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Trafficking protein particle complex subunit 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">TRAPPC12</name>
        <name evidence="3" type="ORF">BGZ80_001327</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000013">
        <property type="protein sequence ID" value="KAG0024570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T4N3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030008">
        <property type="term" value="C:TRAPP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21581">
        <property type="entry name" value="D-ALANYL-D-ALANINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21581:SF6">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14559">
        <property type="entry name" value="TPR_19"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="579"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="103"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="30"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="60"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="133"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="185"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="206"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="229"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0024570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="738" mass="81291" checksum="66A26DDCE312271E" modified="2023-09-13" version="1">MSRNVPFEDPLLHPPTPPSNTEVPTKPQEQELSQGRSSPQYDDGPIPFSTGSSAEGPSVFTPPPFPPRPIANTALATPVEVGAASNTTEAGVATAGFVDPLSAALDSHEHDEYPKAPTEGKSGGDKTTSPQGSSPSINTSTINNSMPSDFPTHLASPPIPHRPTSASGAPFTSFHSALPGPQPETPTSISVSESSAPTVGGVPISSLDSMSNANPKQPPAVGLGFDQPGSVQKDGSTIGQQWTKRQSIGVTTNPSGVRMQDHSDMVRQDLKSPELENPARNLLYGSPSNNPLSGATYPTGESNSQLHITPIGHGRDHSSGIRSPVFAMPQSPMRKEGFPILNSHNMFHEITSTDTMNDIMVKHIPADQRTLRDWRALTEAEQRQASRAEILHELTINNSWRAMTRYTRTQILATPPEQTTELINLWYARLLALVKIGQYEMAQAELEQLGDLWGPQYRYENYPPDMFPGNEFQTKEQQQNSTMRRGSMVPFELFVLKARLQGYLGDSYEAIDQLYSLIMYCKKHGAICRVNEDNIGAQQWHDLTGQLHLMILNYLVELNDYSSATKHGRDLAKAYPQDINFHSGLGRLYLQLGDIERAEEVFKEVEEMVKNHNSETEKAHFKLQLSMNRALLAVTQGQWQVAKSAFEDVLVQEPENLAASNNLVVCELYAGQLNEAIPRLERLMFAYPTSAGTSEPLVFNMATLYELRTEGSLKKKQQMMVEVCKWAGDQFNVGVFKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MCE7</accession>
    <name>A0A9P6MCE7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNI-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_009018</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010005100">
        <property type="protein sequence ID" value="KAF9991611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MCE7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052394">
        <property type="entry name" value="LRR-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24114:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24114">
        <property type="entry name" value="LEUCINE RICH REPEAT FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9991611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="183" mass="19815" checksum="1C162418D968472A" modified="2023-09-13" version="1" fragment="single">TLVTLFIFMTKISWTHPLDLHEIRSRIASSLGLKDLASCARVSQDWNDSFTPPLYNSVVLSKHGPSMESLERNKHLIHHLKIESSAYGKLSWTSARVKIISSIMANSTLTTLHLGENSIDDNGAQALSEALTTNLTLTTLELWGNSIGPNGAQALSEALKTNSTLTTLDLQCNSIGSNGAQAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MCK0</accession>
    <name>A0A9P6MCK0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Carrier domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_008681</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004796">
        <property type="protein sequence ID" value="KAF9992142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MCK0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043041">
        <property type="term" value="P:amino acid activation for nonribosomal peptide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1200.10:FF:000005">
        <property type="entry name" value="Nonribosomal peptide synthetase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF14">
        <property type="entry name" value="PLIPASTATIN SYNTHASE SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="4">
        <location>
            <begin position="72"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9992142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="230" mass="25964" checksum="A456382577B1E971" modified="2023-09-13" version="1" fragment="single">SDKRLVAYVVSDAVDHLAQLMRDHLTTALPEYMIPAAFMRLDSLPLTPNGKIDKRALPKPEVDAFVSQGYEEPRGEIETALADIWTDLLKIERVSRHDNFFMLGGHSLLAMRLLNRISTLGVNLQLSKLFESPILSELADTLASQFEQKKESFDHITPISRDGALSLSFAQQRLWFLAQMEGVSDAYNIPTAIRLQGTLDRDAWKRALNTIFARHESLRSTFVNIEGQPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MCW9</accession>
    <name>A0A9P6MCW9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_008495</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004611">
        <property type="protein sequence ID" value="KAF9992601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MCW9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9992601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="58" mass="6696" checksum="5003E2EAB931BFE1" modified="2023-09-13" version="1" fragment="single">QFVMPDEAPANGVNETNYRTEFQFYKKHWLLTHTVRVYPIKVPSTNTTDDLKKAASPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MD21</accession>
    <name>A0A9P6MD21_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">von Willebrand factor A domain-containing protein 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">VWA8_3</name>
        <name evidence="1" type="ORF">BGZ80_008507</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004626">
        <property type="protein sequence ID" value="KAF9992554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MD21"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039891">
        <property type="entry name" value="VWA8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21610">
        <property type="entry name" value="VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21610:SF9">
        <property type="entry name" value="VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9992554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="139" mass="15357" checksum="345460C953D20365" modified="2023-09-13" version="1" fragment="single">MESFRNFEHKFEYSIIGHSGDSPNLEFVKPGRYPKTEKDVFKVISQMSAHSQYCLSGDNTLSATSMAMREIIKEDADDYIVVVLSDANIGQVTSSMIFIGSLADQASKLKSALGSHAHVCMDTKDLPQIIKSIFLSSMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MDQ0</accession>
    <name>A0A9P6MDQ0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Arm-like repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008091</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004296">
        <property type="protein sequence ID" value="KAF9993555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MDQ0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056251">
        <property type="entry name" value="Arm_rpt_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23948">
        <property type="entry name" value="ARM_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arm-like repeat" evidence="1">
        <location>
            <begin position="225"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF23948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9993555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="310" mass="34634" checksum="F66E7F712851B0D1" modified="2023-09-13" version="1" fragment="single">MFKQLSFSNRRARDIGMLRNLFPSQSSGFSLEETIELVNKRLEDARKENDSAKALELINSAKLLLKDAENIFLSKKVKDRALSESIANAYHEHGTLLDGLGRRGKAKKSQSKAEKWGYVDVVSRDTGSFRPLSDVTDVTQLNNQDHAFHATPAEVNNSKLTPNKDVVQAPQKIFGYNITPPTTKYALPEADQRIASTPQLAYCLSLLHPSMISKEELGQSERDWLQAKDVDPDERERLQTMATDLIRAFVQEGLKKPDVVAEVASLVAILEQDDFRKLLQVFVNGISQSLLLDVHLLNGLAQLIRNAPQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MEP4</accession>
    <name>A0A9P6MEP4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Chromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_007460</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003826">
        <property type="protein sequence ID" value="KAF9995639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MEP4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd00024">
        <property type="entry name" value="CD_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051219">
        <property type="entry name" value="Heterochromatin_chromo-domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22812">
        <property type="entry name" value="CHROMOBOX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromo" evidence="4">
        <location>
            <begin position="144"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="202"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="202"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="213"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="227"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9995639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="237" mass="27637" checksum="FEF20EBF4A635DBB" modified="2023-09-13" version="1" fragment="single">TVHLHNSSPFSLFFARKANGFSNYTNEEDNTMSQEELLKRLEYMTTVVFPTVRERSKITQARMIKRFNATVLHNEFPDGTMVMTLDPIKGNKLSPRYEGPYMVIKRTSHGSYILKDGTGEVLKRHYAPSQLKLVLDDFEDTSTYEVERIVNHRPSRVTPNTVEYSVKWKNYPSSKNTWEPEEHFIERQCIADYWAEHHAKQINTSHNSAATSPKEDKRKAERDAVRPTKKRNISRDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MEY0</accession>
    <name>A0A9P6MEY0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Aminotransferase class V domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_007438</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003803">
        <property type="protein sequence ID" value="KAF9995740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MEY0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43092:SF2">
        <property type="entry name" value="HERCYNYLCYSTEINE SULFOXIDE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43092">
        <property type="entry name" value="L-CYSTEINE DESULFHYDRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotransferase class V" evidence="2">
        <location>
            <begin position="66"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9995740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="392" mass="44633" checksum="6E3535A336018204" modified="2023-09-13" version="1">MTSATELPTPSNPGPFGHKLRKDFLFPENFTQFNHGSFGTFPKVVQDDMIAWHKRAEQNPDIWMRRDLKPALTETRRKLAELIHCDKDELALVQNTTVGINTVLRSLKFQPGDRILQLSTGYISVDKTVRYICDTHEDVKVIEIPITFPLSDKEILDKVEHAIKEHEQLKDGSRIKLAIVDWISSVPSILQPVKQLVDLIQSHGILVYVDGAHAVGQVHIDLADLHPDFFITNCHKHLIHPTSITSDYKSGFENEFSWMGTTDYSAIMSIGAAIDYRKQYGEDAIISYTHALALEGGKVMAEILGTDCLTPHDHQVGNMVNVRLPLKDVNNPKATYQYFADILFDRYNIFTPAFKHGDHWWTRVSAQIYLEVDDFVRLGNIWKEVIDELNAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MFA8</accession>
    <name>A0A9P6MFA8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Agglutinin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007067</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003558">
        <property type="protein sequence ID" value="KAF9997152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MFA8"/>
    <dbReference type="OrthoDB" id="2387820at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040107333" description="Agglutinin-like protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9997152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="389" mass="42204" checksum="81C8581A341BD8D3" modified="2023-09-13" version="1" fragment="single">LILVITILSSFAASVTDVGAVYFILPSSRPSNQNSELVNTTQFFPFDLQKSFDGWSSFVRNGDNITHAMASMINDTNRIPNAIPGRIYTPQTATFNVGCDKMSFYAFNSSAKFLLNQGGCATVNFNTYDSFIASYDNATVVNKPNGRSSIKIPGTYSGQYLLESLPGVDLTYGNTTCSLIGLENGSSVVNGTNGITSVPKTWTTRCVLPTDEIVALSLTTIRFSFFKSQDFRRLTSSMFRDDAELVRAMQGSFKTATNKTIIFSELRFSNTTLEALVCLNTNLGNASPSTSCAYVSVGIVVTTQQEINLIIAGARGSAPSAVSPTPADSLIGYQYNPSIIMTIYHIPTLTNNNTQQLSISEANNASLMSAQYFASLGQNIYMDWNTSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MG69</accession>
    <name>A0A9P6MG69_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">GTPase-activating protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">GYP5_2</name>
        <name evidence="5" type="ORF">BGZ80_006849</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003408">
        <property type="protein sequence ID" value="KAF9998158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MG69"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.750:FF:000003">
        <property type="entry name" value="GTPase activating protein (Evi5)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.270:FF:000001">
        <property type="entry name" value="TBC1 domain family member 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.750">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050302">
        <property type="entry name" value="Rab_GAP_TBC_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219">
        <property type="entry name" value="RAB GTPASE-ACTIVATING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219:SF22">
        <property type="entry name" value="RAB-GAP TBC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="4">
        <location>
            <begin position="546"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="215"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="280"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="374"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="411"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="43"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="68"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="81"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="231"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="280"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="375"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="411"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="433"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="639"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9998158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="639" mass="67468" checksum="74F8C593008D3849" modified="2023-09-13" version="1" fragment="single">SFYGEGESVAPNQNTFQDAGVDHHRVSVNSAKSFSSHSKHHSFGYDDRPAGYGEKFESDSESSTSEGAEERQMAERLMAEASASAAASRPTSASSFSIASRSTPSSPVHTRFTPSAVVAENREIEEEEEPKAVESNTAPVVAAVAVAATAAAAAAAVTVAAVKTTADDTVSVVTPVVAPAPAPAVAVALTPDAPVSPTPSLSHSALLVDTISQKSVSTASSIDRREKRYSGSDSDTSGTSIDLHSPTFKDQAKKTPPTVFSRTMSSLSATRDAVSNNISNTINTINNSNNNNNNTRESSAEKTRPTSYATVFSDAEMNDINLADELPNEKRVSEIVPPTPSTPSGFGFGFFGSRNSQIATGAAAATAAAAAAAAKSSSRPNSALTPTPAPVETRSRSTSISALASSVFSGWGFSSSSQNQPPVPPVPRAASQIGSQRASNVGSVATSNRGPNSGPGSDRASIMSNQTTDSNMDLLLARLEAQNELLAQDSKRRATTESEMDRALGHAKEECAGEDYDWDYWGALMHDYNAVVKRDPRKLTVMIQKGVPPALRGLIWQLLAKSKDLQLEGTYAELLKSSSAHEKQITRDMSRTFPNHEYFQAESVGQEALFNVVKAYSLYDPEVGYCQGLSFIVGPLLLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MGJ9</accession>
    <name>A0A9P6MGJ9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Prolyl aminopeptidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_006859</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003414">
        <property type="protein sequence ID" value="KAF9998108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MGJ9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005944">
        <property type="entry name" value="Pro_iminopeptidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43722">
        <property type="entry name" value="PROLINE IMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43722:SF1">
        <property type="entry name" value="PROLINE IMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9998108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="180" mass="20822" checksum="D61F3C3A458AB99B" modified="2023-09-13" version="1">MLRKSELTWFYEQGGASNIFPDAWDEYLKPIPEEERHNMIEAYHKRLTGSDEEERIRCAKAWSTWECSTSKLYVDPVEVAKASEDIWALAFARIECHYFFNKGFFKTDAHILENIDKIRHIPATIVQGRYDVVCPATSAWDLHKAWPEAQFEFMADAGHSAKELATTARLVKAADEYKTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MGL9</accession>
    <name>A0A9P6MGL9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_006580</name>
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    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003257">
        <property type="protein sequence ID" value="KAF9999373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43503">
        <property type="entry name" value="MCG48959-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43503:SF2">
        <property type="entry name" value="NEGATIVE REGULATOR OF SPORULATION MDS3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="BTB" evidence="4">
        <location>
            <begin position="498"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="241"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="671"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="9"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="278"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="690"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="737"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="768"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="789"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9999373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="789" mass="86028" checksum="AEAA120F28AE5F48" modified="2023-09-13" version="1" fragment="single">MPSPAPGLQSISDLTTTSRITTGDIPPPLVGSTMTVVDDKLYLFGGRLIQNRHMTNSLYILNLIDFHWQNVSEIVNIPPVRAIGDPGAEDENEVGAPPTERYFHSANAYKNTVVFFGGMGPSSNVVADGQSQDLVVFDDISILDLELLRWRQVRIPSSQHAPKPRYAHLSSISGNKLLIIGGQDINNQYIEEISVLDLDSMQWTASMPFEKHCGSYRSIAVSSNGQDSSIPIIGSELGADMTSPILSPTSPAPDGAPTPLLRKAPSNTSLHYAPSLRKSTSSMTMSKMGGSSRLSVGSGAALDTSPPSDQRSSIYRLSHLVTPGPVQKEEQPVYIYSNFNFSDVKRELQVLTPPQFGLQDHSQSMSGNLLPPGLRFPTGAIAGQHLLLSGTYLSHAQQSFSIWSLNLSSLAWTRIDTGTVFSTGSWNRGVLLESSNAYLVFGNRSRSLADDYQNRQTNFEHVSIVDLEAFGIYQHPPTTMTQTAQELGLSLLGDHSMADFEILTQDKQRIPVNSAVLATRWPYFAALLRDQEEQDAAQCKLDNVEYDPTLSQKRTLSLPEPYAVVLAFLQYLYTDHLVTAQQHQSQVLSQLLLLADMYGLERLRDLATHALHQMLNMSTAAMVYETAALSQQTGLQIRSLKVMIAAKKMLQQQQLKLQQQQTLSQGVTAWSSSEIGNGGEQHHNNGGYSSGSILQPPLSSFMSQQQDIHSVFQPNSTSAPLSPTSSVGGFSQDHRTSTQLTGAPNQSGRNRSSVTGSMPPHRWNTEPLTPPPVSPPPTASSVPATPPPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MH71</accession>
    <name>A0A9P6MH71_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_006463</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003190">
        <property type="protein sequence ID" value="KAF9999958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MH71"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9999958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="160" mass="17680" checksum="B986A5ADED52C5EF" modified="2023-09-13" version="1" fragment="single">MSCESCTGCFEATPCSAPAPSINGHISKEYRQFLKAARVCAALSTTNSGTTIDSDKELSRKGENLDHAFNSLISILASNQFTAQTYLAQSYRQLGSGHFLQLSRTLAHHGFWGRLITWAFLFVGEDSPKLQSLLDQHDEMLLQNVNDEAEMFEVFNPAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MKN8</accession>
    <name>A0A9P6MKN8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_005269</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002605">
        <property type="protein sequence ID" value="KAG0006485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MKN8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0006485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="62" mass="7003" checksum="AEBFF80CB35D71CF" modified="2023-09-13" version="1" fragment="single">MDEGAPMVPLIQIVYKTATVYRMFVRTRGVMVLAEVGIFTVPMHLSAVADFQASIQVLEWFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMM8</accession>
    <name>A0A9P6MMM8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">glucan 1,4-alpha-glucosidase</fullName>
            <ecNumber evidence="3">3.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BGZ80_004577</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal (1-&gt;4)-linked alpha-D-glucose residues successively from non-reducing ends of the chains with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.3" evidence="3"/>
    <dbReference type="EMBL" id="JAAAID010002319">
        <property type="protein sequence ID" value="KAG0007513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMM8"/>
    <dbReference type="OrthoDB" id="6123450at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004339">
        <property type="term" value="F:glucan 1,4-alpha-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00111">
        <property type="entry name" value="Trefoil"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.110.10">
        <property type="entry name" value="Spasmolytic Protein, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011613">
        <property type="entry name" value="GH15-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000165">
        <property type="entry name" value="Glucoamylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017957">
        <property type="entry name" value="P_trefoil_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000519">
        <property type="entry name" value="P_trefoil_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044913">
        <property type="entry name" value="P_trefoil_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31616:SF9">
        <property type="entry name" value="GLUCOAMYLASE, INTRACELLULAR SPORULATION-SPECIFIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31616">
        <property type="entry name" value="TREHALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00723">
        <property type="entry name" value="Glyco_hydro_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00088">
        <property type="entry name" value="Trefoil"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00736">
        <property type="entry name" value="GLHYDRLASE15"/>
    </dbReference>
    <dbReference type="SMART" id="SM00018">
        <property type="entry name" value="PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57492">
        <property type="entry name" value="Trefoil"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00025">
        <property type="entry name" value="P_TREFOIL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51448">
        <property type="entry name" value="P_TREFOIL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5 9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040114762" description="glucan 1,4-alpha-glucosidase" evidence="10">
        <location>
            <begin position="19"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="domain" description="P-type" evidence="11">
        <location>
            <begin position="25"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="38"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="48"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0007513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="535" mass="58729" checksum="78CD93B3C6B78DF8" modified="2023-09-13" version="1">MKPITILAAVAFLKVTLASPLVARATCTNIEGIYRNDCGTIGVSESTCSSGGCCWNPSTDGSPWCYYPDPISFSRPTPPDQDAITSWASSQYTYSLSAMMNNLSPAGSKTGCVVAAQSQTNPQYYYHWSRDGALTMYAITLQYINAIKSGDVTLQSTYATLVKNWISFEYGLQSITNPTVSITGNMQDNVGEPKFNIDGTAYTGSWGRPQNDGPGLRTRTIVKFLRAYVPNTGDTSYASSLYNMISRDMSYVVRHYADVCTSGTPCVDLWEERSDSHFYTDMSQRRGLKEGAYYMNTWGSNSTLASQYLSVASALEPRVDAHWMDSLSYYKEMLDVSDRNSPDAAIILSSIQSRDETDPFVSPSSDKMLSSAYRYATQFRGHFQINKDRMAYAPAVGRYLEDVYNGGDGVNNNGAGAWLLAINAVAELHYVAAAEFKIAGQASVTAINQPIFAYYGVNATPGSVLTGSQLSTLITNIFGEGDSYLDTLQYHMGSEQDMTEQFNPVTGYRQGAKHLTWSYASFITAIEARNTFLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MN43</accession>
    <name>A0A9P6MN43_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004653</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002350">
        <property type="protein sequence ID" value="KAG0007441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MN43"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="239"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="332"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="405"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="48"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="88"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="240"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="332"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="345"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="359"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="405"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="424"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="435"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="458"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="488"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0007441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="672" mass="69171" checksum="6184DAC27FA5BDB7" modified="2023-09-13" version="1" fragment="single">TITTTIASIAGSSGALAVPDRARAALKNYNIDGLNTSGPAPSIAPEQTLSRKSSTISSDSGSTTISKSTNPSSTGSSPFNAAGPKNPQQQLQQYQQNQYQASSPLQQVQQPQTNASFDDFASLMNAGNNAFGNNALGNSALGNSALGNSAIGNSALGKNALGNSVIGNSALGNSALGNSALGNSALGNNALGSNAFGNNALGNNSSILGVQAFVSTPAADNSSDPFSLMTNAFNNMGVGSSHTSSTDSYPSNNSRYGSINGSGSGTLTGTGRAMSSQTSSSLSPNEFFATFSSGATSSASIHATNAVESSDPFSLGASSQSYLQLQQQQQQKSSQLGSLHGLDFNLSSTPQVNNTLPPTSTATSTGAGTGTATKSFDDYLSILGNGKQPQLQQTSTLSSHSNLYNLSSSTSSSPFSTPSASLSPQSTGVSNPFGQQAQPQQYQQQQQQQQQKPPQFQRALTTDSAHLSAASSSTNGQQGNPFAMFAKQQQQPVSSSPLQSALTGPFGRHQYQPQQQQHNDYFTMPGLNSSGTRSPNPFMMSGQTAQTQQGSMPTTFMRSVSDSSNNFQNAFNNNNINNTNNIGSSIGYSSLNGGVGSTANFESAFSVPAAHSRSMTVPVTSTNDMFGQWVKPSPVAANTKYPSIDDLDPFSASAPTAAAPASAFSNPFSLNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MN69</accession>
    <name>A0A9P6MN69_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytidyltransferase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_003454</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8 12">
            <text>beta-nicotinamide D-ribonucleotide + ATP + H(+) = diphosphate + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:21360"/>
            <dbReference type="ChEBI" id="CHEBI:14649"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="EC" id="2.7.7.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; NAD(+) biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001914">
        <property type="protein sequence ID" value="KAG0008431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MN69"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000309">
        <property type="term" value="F:nicotinamide-nucleotide adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD+ biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02165">
        <property type="entry name" value="NMNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005248">
        <property type="entry name" value="NadD/NMNAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31285">
        <property type="entry name" value="NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31285:SF0">
        <property type="entry name" value="NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cytidyltransferase-like" evidence="9">
        <location>
            <begin position="51"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0008431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="268" mass="29805" checksum="BD79CA9F55D315A5" modified="2023-09-13" version="1">MRKPFLQKALAAATSTPPKPFQTTFTATSSWPFTADRPASTVRPTRIAVLDSSFNPPTKAHFHLLKAATRIGCDAVLLLLATNNADKGQTGAGAIERLEMMEAMAMDAISNEKDDPALCQMAVGLTIHARFMDKAQPILDQYPTNTVQLSWIMGHDTMTRLFDPKYYKDVHADMAPFFEQCDVICSSRPGYGSRDEMMRFVEQSGYTDKVTLVDIETEGEDAEHGIEIKEMSSTVVRNAVKSKNWALVERCVLPSVRNFIEKNGLYNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNN6</accession>
    <name>A0A9P6MNN6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_003348</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001880">
        <property type="protein sequence ID" value="KAG0008523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNN6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0008523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="263" mass="29910" checksum="1F0D22B7B3880E63" modified="2023-09-13" version="1">MSLVDSTVATSSPRHGRKEITMYCEMGFQHFNIQVILGLSIKDFNPKDIAVEVYRELDELLAKNPRNLQQHSGTGRQVALVGEGEDDSIDPTLSSTHIKRIKSPLREPTIRCDIRNPDKYVRRWFLGKVIVVPRVPSFGGLAVEATLRRAPTLERIAIDGCRQMTSKYVQLLLARAPHLFEFGYSIQFMNPIEDSDVDDDDESELGEYYEVHVELQPGEDFEYEEYVLGFQEDCLQFSPLTGLVSNLKVMHILSIHCVQPPEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNY1</accession>
    <name>A0A9P6MNY1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase</fullName>
            <ecNumber evidence="4">1.1.1.302</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one reductase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">RIB7</name>
        <name evidence="14" type="ORF">BGZ80_003142</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes an early step in riboflavin biosynthesis, the NADPH-dependent reduction of the ribose side chain of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, yielding 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>2,5-diamino-6-(1-D-ribitylamino)pyrimidin-4(3H)-one 5'-phosphate + NAD(+) = 2,5-diamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:27274"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58890"/>
            <dbReference type="ChEBI" id="CHEBI:59545"/>
            <dbReference type="EC" id="1.1.1.302"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>2,5-diamino-6-(1-D-ribitylamino)pyrimidin-4(3H)-one 5'-phosphate + NADP(+) = 2,5-diamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:27278"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58890"/>
            <dbReference type="ChEBI" id="CHEBI:59545"/>
            <dbReference type="EC" id="1.1.1.302"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; riboflavin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the HTP reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.302" evidence="4"/>
    <dbReference type="EMBL" id="JAAAID010001813">
        <property type="protein sequence ID" value="KAG0008707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNY1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008703">
        <property type="term" value="F:5-amino-6-(5-phosphoribosylamino)uracil reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="entry name" value="Dihydrofolate Reductase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002734">
        <property type="entry name" value="RibDG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050765">
        <property type="entry name" value="Riboflavin_Biosynth_HTPR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38011:SF7">
        <property type="entry name" value="2,5-DIAMINO-6-RIBOSYLAMINO-4(3H)-PYRIMIDINONE 5'-PHOSPHATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38011">
        <property type="entry name" value="DIHYDROFOLATE REDUCTASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_8G06820)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01872">
        <property type="entry name" value="RibD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="Dihydrofolate reductase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0521">NADP</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0686">Riboflavin biosynthesis</keyword>
    <feature type="domain" description="Bacterial bifunctional deaminase-reductase C-terminal" evidence="13">
        <location>
            <begin position="5"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00015035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0008707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="152" mass="16447" checksum="2504CE0938ECEA96" modified="2023-09-13" version="1" fragment="single">SSPIEHPQPIILDAKLRFPKSAKLVLPAAPKKPWIFTGLSCDDQRKRELEDLGAKVFMLDVDSLGHLSLPSLLSTLSEQSIRSLMVEGGAGVISSFLKSGLVDSFLLTIAPVYVGEDGISAVQHAESAAKFDNISYHTLGRDVMMVAKQQSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNY6</accession>
    <name>A0A9P6MNY6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ricin B lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003925</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002070">
        <property type="protein sequence ID" value="KAG0008045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNY6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23714">
        <property type="entry name" value="beta-trefoil_Ricin_MtaL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040460659" description="Ricin B lectin domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0008045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="178" mass="19706" checksum="434A701FFB9D156B" modified="2023-09-13" version="1">MVRTTVSFIALSLIAVQAAIAQTLESGVYRIYDSYGRNAFGVGPIPIIYPPPDVPLRLFTGGSPLVDRWYVVRTSGDRYTIRVGSGRSGDYRIIPRGNDVFVTATKAPQEWSITEAGDGQFVIQILNQDSIVTSEEERRPPLALEPANGSPDQRWRFVRIGDDDSCAISTRVQSTNYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPA7</accession>
    <name>A0A9P6MPA7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">C2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003201</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001835">
        <property type="protein sequence ID" value="KAG0008655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPA7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32246:SF173">
        <property type="entry name" value="C2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32246">
        <property type="entry name" value="INGRESSION PROTEIN FIC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2" evidence="1">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0008655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="198" mass="22104" checksum="40A95E9E8E43C743" modified="2023-09-13" version="1">MAHTINIFVHSANHLEDVERFGKNDPYAQFTLNFEDKSFFQKTATKKNAGSDVEWDQEVNLDYYNPEDHNNLYVEVFDEEASVDAPIGFAAIPLRQVRDAPHHSLKARYDLFRPNGDQKGTIDLTISILKPGQEARSATAGKPEEKGFSELDAQHQHHIKNKRNLERAGDAAALLAGVAALAGAKAVYDHQKKAAHEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPI9</accession>
    <name>A0A9P6MPI9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ribosomal RNA-processing protein 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">RRP7_1</name>
        <name evidence="3" type="ORF">BGZ80_002547</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001632">
        <property type="protein sequence ID" value="KAG0009289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPI9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032545">
        <property type="term" value="C:CURI complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034456">
        <property type="term" value="C:UTP-C complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000028">
        <property type="term" value="P:ribosomal small subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040447">
        <property type="entry name" value="RRM_Rrp7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040446">
        <property type="entry name" value="RRP7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13191">
        <property type="entry name" value="RIBOSOMAL RNA PROCESSING PROTEIN 7-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13191:SF0">
        <property type="entry name" value="RIBOSOMAL RNA-PROCESSING PROTEIN 7 HOMOLOG A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17799">
        <property type="entry name" value="RRM_Rrp7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rrp7 RRM-like N-terminal" evidence="2">
        <location>
            <begin position="22"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="145"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0009289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="218" mass="24812" checksum="148C0627D61568C0" modified="2023-09-13" version="1" fragment="single">MVSKKSKKSEESSTSSAQLDQIANFYILPLHMPAISTTHSSPTYKNVLHYLYFKKHESPKQDAKTPKDRTLFLLNIPVDATESHIRDLLKPYGRVASIHFLNRVRDSNLSKEEREQQEELERLEREAEAAEEAQNNKTKKGSKKQQQQQQQQQQQATGAEDTQRRKLFATGSQAYVVFLEEQELVKALNMKKKKRSWIVTGPEATLADAAKLSSLGVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQ53</accession>
    <name>A0A9P6MQ53_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_002544</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001630">
        <property type="protein sequence ID" value="KAG0009298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQ53"/>
    <dbReference type="OrthoDB" id="545169at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046366">
        <property type="entry name" value="MPAB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018713">
        <property type="entry name" value="MPAB/Lcp_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36124">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36124:SF1">
        <property type="entry name" value="ER-BOUND OXYGENASE MPAB_MPAB'_RUBBER OXYGENASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09995">
        <property type="entry name" value="MPAB_Lcp_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="domain" description="ER-bound oxygenase mpaB/mpaB'/Rubber oxygenase catalytic" evidence="2">
        <location>
            <begin position="141"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0009298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="327" mass="37216" checksum="1B43F63B12D855E7" modified="2023-09-13" version="1">MAHPSLLSAGVGVAALGVGISYSFLRRQHFARSWRKQLEELDPKKPNDTDLIIKHVVGYDYPLEMFLALNFCFYRTFCSPTIAGVYRNTGAIANTADKRACDTDLLMHIWMDYGLDSELGKSSYLHLNKIHGLHATKTRNVDFVFVLCCLVVDAIQFTNDYGWKKLHSKEKQAIWEFYHRVGERMELKDIPNSLEECIAFVDKYTEDNRSARVSKDGVALTKVITDLVCEWYYLAPPFLCRIAASVLLYQMGPTFHSKLGLEKPSIFSFALINSALWVRKQILRLTPPRTIPYKLSDVIMSTKYSCPVSKQSIVQVGPVEMLEKINA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQ65</accession>
    <name>A0A9P6MQ65_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_002404</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001590">
        <property type="protein sequence ID" value="KAG0009429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQ65"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050562">
        <property type="entry name" value="FAD_mOase_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356:SF2">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356">
        <property type="entry name" value="FAD-DEPENDENT MONOOXYGENASE ASQG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="14"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="303"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0009429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="406" mass="45494" checksum="A1825ABDD5FFAF9C" modified="2023-09-13" version="1">MVDMTDLADVHIPTVLIVGAGLGGLMLGAVLKSANISYHILERAAEPRPLEFSIAISANILPVFEQLGIYEELKSVSLPLLTVSLFDKNLVHLGDFGGPYHKIVTGYDIQMLARPKLYDILHRKVPSYKISRGKKVLRTKEHDDRVTVYCSDGTEYDCSILVGADGAYSAVRQSMYKKLDEEGNLPLIDKEDLTIGYITMVGVSTPLNPEKYPQLSETDRSYFHVVVGDKNDSHYFVTVPDNQICWGIKIQLPEHEAKQQQFKNFEWGPESVDIMLKEYENFPCAFGGTMEDLFDTTPKHLISKVFLEETVFQTWYHGRSVLIGDACHKLLPGGGEGAAMAMRDAVVLANCLYNMSDKSDKSIKGAFANYYRQRYLDAEDKAKSSAISTRIMSGHLVTEEGFYRHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRG6</accession>
    <name>A0A9P6MRG6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_000977</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001216">
        <property type="protein sequence ID" value="KAG0011060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRG6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0011060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="115" mass="12472" checksum="5BB3E1E05491EB25" modified="2023-09-13" version="1" fragment="single">IKDKVQSIKSLVTSKKGDQTEEEPELTPANLSPKGPVSQVRQFTFKDKSNASTHLVRNALGGGDEGKLAATLSIPAPMSRVYRDDITVTVVFFGQHDTKVDLSNAQDNDGFVEIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MS31</accession>
    <name>A0A9P6MS31_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_000672</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001144">
        <property type="protein sequence ID" value="KAG0011460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MS31"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF309">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14510)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="21"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="304"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0011460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="444" mass="49462" checksum="9D551B122D39ED45" modified="2023-09-13" version="1">MENIYPSQPPPISPNGKIPHVMIVGAGLAGLFLAILLDRISVPYEIYERTEEVRPLGGVMCLNANILPAFEQLGLIDELRKVSLQSRTFNIYTGNMEKIGIFGNDDKLSESIGYDNHLFSRPVLYDLLLSHVPAERIHFKKKVLSIARNKEGAMIRCSDGTTYHGDILVGADGANSSVRQSLYKLLQDKGQLPDSDTKGLSKCNIFMVGTTKPLDPEKHPCVSEPTAILYQMIGEGTPYTWSSMTVRNHQICWGVVKQLGLAESQNEKFRSSEWGPETSEAMIKDVRDFRIPTGTLGDLIDATPKENTSRVFMEDKLFETWHHGRTVLIGDACHKLLPSSGQGAVNAMQDAVILANCIYELKSTAEDDVAEALRDFKEQRYPHVKRQYEASKMSAKLLYGQSMSADLVYRPQASFLPLAPTRGTLNILPQKPSKSSKYYAQNTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSS4</accession>
    <name>A0A9P6MSS4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sphingosine kinase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">SPHK2</name>
        <name evidence="2" type="ORF">BGZ80_000046</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001001">
        <property type="protein sequence ID" value="KAG0012326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSS4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001727">
        <property type="term" value="F:lipid kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046512">
        <property type="term" value="P:sphingosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001206">
        <property type="entry name" value="Diacylglycerol_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050187">
        <property type="entry name" value="Lipid_Phosphate_FormReg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12358:SF31">
        <property type="entry name" value="ACYLGLYCEROL KINASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12358">
        <property type="entry name" value="SPHINGOSINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00781">
        <property type="entry name" value="DAGK_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00046">
        <property type="entry name" value="DAGKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="NAD kinase/diacylglycerol kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50146">
        <property type="entry name" value="DAGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAGKc" evidence="1">
        <location>
            <begin position="207"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0012326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="330" mass="36936" checksum="80F294E94EFC8779" modified="2023-09-13" version="1">MGIVSVLSNTIGVLALDYLSKCRNYGIVGSGYFQQVRWYSRGFRRNAQIEYTSALEFIKSISSNLKPKVIRVSPMGGPEGGIDQASYRNNQHKIWILNKDPHIQEMASELEFKVLRNEVMSGEATHKIVERFPYCCIYGYNAPNKSVLESSVQDSSQDQLFTLHYVKFTSLDLKAVSSPKLARIYLLFDQQPDVKRFLALTEQLGDTEYGKHAVDIAHKVDLKELDTLIVISGDGVLHEIINGLLTRPDWDQARHLPIGIIPAGSGNAIATSIGTRNPIVATLAVIRGETSKLDIFSLSQLDRPRIYSMLMFSWGMMADADIESDKYVLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSV7</accession>
    <name>A0A9P6MSV7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_000119</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001019">
        <property type="protein sequence ID" value="KAG0012214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSV7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="273"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="273"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0012214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="377" mass="41230" checksum="F97F4B674C61A5DF" modified="2023-09-13" version="1">MNSLVNYASESESESDESPPIVAASKQTSSASPSTAKSIVHANEVSTAISKEPQRSSPGKNQDHGNDDDDAMDVDDSASGSGDEGYVMAALKDLQSFAATVDTANDDSTIPQPSLTTPKEPLDTSTSAPGISNESQNTSSTLASKPAESESIESTLSNLSIELSAEQQTLFDEFLREIDAIPLTSKNQSKPPTIDKTPIEDDLLFSELQWLQTQSVQSIYSRMHQLSTLQSPTIDHKDMEARLIEFAIRILDWEHGGMKPEYFLGEERALAEGKKNATENTLDHKDSSDSAEEEDDGDEESTSVMPPYGGVVGEMLERMAAIEQTAAPSGWRVVWDPEECTYKFKHITTMYRSIADLSMCILSSYDKICYDAERDEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTP6</accession>
    <name>A0A9P6MTP6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phosphotyrosine protein phosphatase I domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_011781</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000991">
        <property type="protein sequence ID" value="KAG0012387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTP6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046685">
        <property type="term" value="P:response to arsenic-containing substance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023485">
        <property type="entry name" value="Ptyr_pPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036196">
        <property type="entry name" value="Ptyr_pPase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43428">
        <property type="entry name" value="ARSENATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43428:SF1">
        <property type="entry name" value="ARSENATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01451">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00226">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52788">
        <property type="entry name" value="Phosphotyrosine protein phosphatases I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0059">Arsenical resistance</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphotyrosine protein phosphatase I" evidence="2">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0012387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="127" mass="14126" checksum="E79D4B143DFCA5A7" modified="2023-09-13" version="1">MFACVHNAGRSQMAAAFFNKHRTRDGIKGISAGTNPASEVHGVVREIMLEEDIDLSHIKPVKLTPELAQTCSTIITMGCGEACPYVPGVKIIDWQITDPKNKSLDEARKIRNEIEIKIKVFITENNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUS7</accession>
    <name>A0A9P6MUS7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">malate dehydrogenase</fullName>
            <ecNumber evidence="3">1.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BGZ80_011351</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(S)-malate + NAD(+) = oxaloacetate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21432"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.37"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the LDH/MDH superfamily. MDH type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.37" evidence="3"/>
    <dbReference type="EMBL" id="JAAAID010000901">
        <property type="protein sequence ID" value="KAG0013031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUS7"/>
    <dbReference type="OrthoDB" id="4069699at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030060">
        <property type="term" value="F:L-malate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01337">
        <property type="entry name" value="MDH_glyoxysomal_mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000013">
        <property type="entry name" value="Malate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.110.10:FF:000001">
        <property type="entry name" value="Malate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.110.10">
        <property type="entry name" value="Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001557">
        <property type="entry name" value="L-lactate/malate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022383">
        <property type="entry name" value="Lactate/malate_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001236">
        <property type="entry name" value="Lactate/malate_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015955">
        <property type="entry name" value="Lactate_DH/Glyco_Ohase_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010097">
        <property type="entry name" value="Malate_DH_type1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01772">
        <property type="entry name" value="MDH_euk_gproteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11540">
        <property type="entry name" value="MALATE AND LACTATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11540:SF16">
        <property type="entry name" value="MALATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02866">
        <property type="entry name" value="Ldh_1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00056">
        <property type="entry name" value="Ldh_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000102">
        <property type="entry name" value="Lac_mal_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56327">
        <property type="entry name" value="LDH C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0520">NAD</keyword>
    <keyword evidence="5 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Lactate/malate dehydrogenase N-terminal" evidence="12">
        <location>
            <begin position="2"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="Lactate/malate dehydrogenase C-terminal" evidence="13">
        <location>
            <begin position="147"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="176"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="8"/>
            <end position="14"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="116"/>
            <end position="118"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="229"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0013031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="328" mass="34395" checksum="071BE1FEDB3F6A20" modified="2023-09-13" version="1">MVKVVICGAAGGIGQPLSLLLKQSDLISHLALFDVVNAPGVAADLSHINTRSKVTGHGKEAMSEALKDAHTVVIPAGVPRKPGMSRDDLFKINAGIIRDLAEGVANNCPNAFVLVISNPVNSTVPIVCEVLKKHGVFNPKKVFGISTLDVVRSSRFVSEVNPAVDPSTRVTVVGGHSGVTIVPLLSQIPGGFVDGLSEEKLGELTHRIQYGGDEVVKAKDGAGSATLSMAYAGARFTLKLLEATVAGKSGLVESSYVNLDADVEHTAEFKSKTGLDYFAQDVEFGTEGVSKIIPLPEVSAYEKKLLEAAIPELKINIAKGASFITDSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MV11</accession>
    <name>A0A9P6MV11_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HEAT repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_010335</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000708">
        <property type="protein sequence ID" value="KAG0014623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MV11"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13646">
        <property type="entry name" value="HEAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0014623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="265" mass="29251" checksum="BD912F00040B73DC" modified="2023-09-13" version="1">MTTSDNSDGRSALGSMSYFPEELLIRSLGQPGASQEYMIRTLETRTSLTQSAVEVLLEVLQGNGGPKEIAVRALGKQSTLPESVLQALIDALQHENLDNVDVRRRAVEVLEKQSTLPESAIQALIGALQHENLDVRWRAVDALGEQSTLPEFALQALIDALQHEYEDVRRRVHAEGLVFDGNNAPYHHGYGGMASSSKAHTFLHSFRISSSSKAEESVVMKIEPNVGLGFETPLSKRLADITDKFMFIDGSIRLFQDEIASYHCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MV20</accession>
    <name>A0A9P6MV20_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_010323</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000705">
        <property type="protein sequence ID" value="KAG0014649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MV20"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00160">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000219">
        <property type="entry name" value="DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051092">
        <property type="entry name" value="FYVE_RhoGEF_PH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001331">
        <property type="entry name" value="GDS_CDC24_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12673">
        <property type="entry name" value="FACIOGENITAL DYSPLASIA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12673:SF270">
        <property type="entry name" value="FYVE-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00621">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00325">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00741">
        <property type="entry name" value="DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50010">
        <property type="entry name" value="DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DH" evidence="2">
        <location>
            <begin position="214"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="851"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="916"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1026"/>
            <end position="1058"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1084"/>
            <end position="1109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1168"/>
            <end position="1212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="851"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="865"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="956"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="998"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1035"/>
            <end position="1051"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1095"/>
            <end position="1109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1168"/>
            <end position="1182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0014649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1278" mass="141681" checksum="1F9E69973C08F492" modified="2023-09-13" version="1">MKLTKDPMKRLTRNESNGAYRHRPSLSLNSSKKALLNLQDRRVFKLHAKVPRLPGIKTIATSTPTLATSATFIYSTELSNTRRTSEAMGNDLLILCSDTPNIATPLESQAAVTNSVGEEGIVETTLKESNTSEDAVQSREQCHGLDETMGTGASNESDADNYVLTTDPQDQTPIGPIQCITKVEFGSALSSALEALSIDPRPELDAKETKRFVKRSHALKELEATEESYVNDLDVLLHVYLRVLETKPWFPQNIQVKMCRCVNGLLAMHRNFHSRIEAGVSGDSDHERYLPLRVYKSLAESIKILSRDNYLYSAFCELRMRTVNEINKSAGQATMTLLQRECKDLMLQQGRPSSRSDLKDFLIKPIQRICRYPLLLKEILRLTNQNDPEYQYIEQAYQLMKGKAREMDENQRMVERRLLTEQFLKKLPDTSFPRKVGLISNKEQSVSSDMNLGNSTSVNSSIHPYQTSTGSIHHDGNSGGLTFNSEFVSDNCFDFGSGLEGFNPAALTKAFAGTLGSIILAGALEYVITPDMPVRLKYYGCILFETMLIVVKVKKSNLYEPRQWLPLRLCELHETTRLDGYTQFGWKIMFDQFRIDFGANSVAEQQVWINTLQDRIWIAKEAYIRLPRDVAIFETVVSSLPWKANSSFAAGYMNAHQQQISHKSPSFSPSPWSSCSSAIPSPLMPPPPSVSSSTMMMAMSSMVTIEPEKWNSRGYGQTLDSHAYRQDLCPPDHQLGSKFSEKVRELSVGNHESTRIGGMTSNWSSDKEVSDQNQCFLSPRNAHDYQTRSEPQLLNPSTPMPRFLYGNRPKNNSFDVARAFASSNNSIKPNQKILVQNLFKDVSTEHIWTSSAAVQPSPQSASVLSRHNSSNPLSDSQPIATPSSPQMNTSGVFNVPSAWDSTGSVTLLGEDSYTSMHVAGSPSSSLTSRRRDSGMGVQPLPSVAAGNLDKSDWDQQRNSATSTIAGTLSLNFRKNSDPQQHRHHRRSSSIVETGRYGSESQEGTVSSGDGCETPAILTQEPYSLLSGIRPTENSGDDHSEGPPFEAGKELHQQQPNIGDSQEHCALHEEVLFQNEQPSLMSVTILGRTSTKDTRSTVTSYNSSLGYSDHTQTDFIGSSHSMDSDMCLDESEATLTSSTPPRPALTTFVSASNCSAKTKSQDLLSLFAQENGQPANSNRNSKVVSKPRPGYQPQDQRRPDLLSSTSSQGRRKSLSIFQNITNSASQKFRSLIRSQNGPKRRTVMGLSPTIMECSSSLDDLAAEKATEEKDKGCLNETMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MV22</accession>
    <name>A0A9P6MV22_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 11">Tyrosine--tRNA ligase</fullName>
            <ecNumber evidence="1 11">6.1.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 11">Tyrosyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">MSY1</name>
        <name evidence="13" type="ORF">BGZ80_010416</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9 11">
            <text>tRNA(Tyr) + L-tyrosine + ATP = L-tyrosyl-tRNA(Tyr) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10220"/>
            <dbReference type="Rhea" id="RHEA-COMP:9706"/>
            <dbReference type="Rhea" id="RHEA-COMP:9707"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78536"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.1" evidence="1 11"/>
    <dbReference type="EMBL" id="JAAAID010000722">
        <property type="protein sequence ID" value="KAG0014481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MV22"/>
    <dbReference type="OrthoDB" id="337870at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004831">
        <property type="term" value="F:tyrosine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006437">
        <property type="term" value="P:tyrosyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00805">
        <property type="entry name" value="TyrRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.240.10:FF:000001">
        <property type="entry name" value="Tyrosine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="entry name" value="RNA-binding S4 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.240.10">
        <property type="entry name" value="Tyrosyl-Transfer RNA Synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02006">
        <property type="entry name" value="Tyr_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054608">
        <property type="entry name" value="SYY-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002307">
        <property type="entry name" value="Tyr-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024088">
        <property type="entry name" value="Tyr-tRNA-ligase_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024107">
        <property type="entry name" value="Tyr-tRNA-ligase_bac_1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00234">
        <property type="entry name" value="tyrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11766:SF0">
        <property type="entry name" value="TYROSINE--TRNA LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11766">
        <property type="entry name" value="TYROSYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22421">
        <property type="entry name" value="SYY_C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01040">
        <property type="entry name" value="TRNASYNTHTYR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55174">
        <property type="entry name" value="Alpha-L RNA-binding motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50889">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RNA-binding S4" evidence="12">
        <location>
            <begin position="426"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00033323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0014481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="493" mass="54070" checksum="9D0B897C68C1400B" modified="2023-09-13" version="1">MHAFSAFARNYRGHPIRPVLFQQKQLFAIRFSSSVASHVTRNPVLELQQRGLVAAMTSPDLVGHVEAGPTAIYCGVDPTASSLHLGNLVTLLGLLHFHIKGHTTIGLVGGATGSIGDPSGKSTERQPMSAATLSKNVEGIDAQFQQFFKRGRAYAERRGYSIQGSGGHVKVVNNKTWFGKLSALEFLGDIGRYARVGTMIARDSVKSRLESPQGISFTEFSYQLLQAYDFWHLYHEDGCRIQLGGSDQWGNITAGIDLIHKKKKTTEEQVVIGSSNNENEKAPNAYGLTIPLLTTATGEKFGKSAGNAVWLDETMTSLFDFYQFFVKTADADVGRYLHYFTLLNADEINSVMEQHNAEPEKRFAQHTLAKETTELVHGVEAVPKALLATHVLFGASLEDVKGQELIDAFKHDSRLVPLSKSQVAEMNVDRVALESGLCASKSEAKKLVKSGGFYINNVKVTDASYRIAEKDWINGAVCVLRSGKSNYKLVRAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVK4</accession>
    <name>A0A9P6MVK4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">SURF1-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">SHY1</name>
        <name evidence="6" type="ORF">BGZ80_010306</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Probably involved in the biogenesis of the COX complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Mitochondrion inner membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SURF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000701">
        <property type="protein sequence ID" value="KAG0014683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVK4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033617">
        <property type="term" value="P:mitochondrial respiratory chain complex IV assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002994">
        <property type="entry name" value="Surf1/Shy1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045214">
        <property type="entry name" value="Surf1/Surf4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23427">
        <property type="entry name" value="SURFEIT LOCUS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23427:SF2">
        <property type="entry name" value="SURFEIT LOCUS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02104">
        <property type="entry name" value="SURF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50895">
        <property type="entry name" value="SURF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0014683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="130" mass="14468" checksum="39BE0B19F5A817AB" modified="2023-09-13" version="1">MANITATGRMLLQKQRLHCSPAFAMRPFGIASTPARALSTSTVYPTRSIKLNCIPKQIQGNGYSTLHQVSHTQSGRARWGPLTIGLALCPIITFGLGTWQVQRLRWKVDLIESLEDRMSLEAIPLPRKVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVR1</accession>
    <name>A0A9P6MVR1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Disintegrin and metalloproteinase domain-containing protein B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_009832</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Probable zinc protease.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000624">
        <property type="protein sequence ID" value="KAG0015490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVR1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.70.10:FF:000003">
        <property type="entry name" value="Disintegrin and metalloproteinase domain-containing protein 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.70.10">
        <property type="entry name" value="Disintegrin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001762">
        <property type="entry name" value="Disintegrin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036436">
        <property type="entry name" value="Disintegrin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001590">
        <property type="entry name" value="Peptidase_M12B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11905">
        <property type="entry name" value="ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11905:SF159">
        <property type="entry name" value="ADAM METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00200">
        <property type="entry name" value="Disintegrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13688">
        <property type="entry name" value="Reprolysin_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00050">
        <property type="entry name" value="DISIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57552">
        <property type="entry name" value="Blood coagulation inhibitor (disintegrin)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50215">
        <property type="entry name" value="ADAM_MEPRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50214">
        <property type="entry name" value="DISINTEGRIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="639"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M12B" evidence="8">
        <location>
            <begin position="205"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="domain" description="Disintegrin" evidence="7">
        <location>
            <begin position="448"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="684"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="715"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="363"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="362"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="366"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="372"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00056552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00074021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0015490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="759" mass="81666" checksum="91BC638F60DAA9AE" modified="2023-09-13" version="1">MAFKGVVVQDEYHSDRKWDRAARTSRVEKRTVEHMLHEDGVLGWARMMIEHDPDNRDAIVLRGAFMTDAETFHVTTLQHYHVQKRSDDATPLNTQSAGSNLVIYRDSDLYTRSSSLRRKRGIAQEEESSCGVESLAHHSRIDGDAPIMHEYYHPPNLTSSIPLREAHDLSSSWNTLWNNGPLIKRQVAVKVAGPNPVPDGCPANRLVNYMGVAADCTYIRSYGGAVGARKQILADFNTASGIYESTFNVALGVIALNIVPDGCPTVPVKSQEWNQECSTGYTIDKRLSDFSNWRGQGSRPNDGAGLWHLMTKCNTGAVVGIAWTKALCQMKSQKQKSNGVEEVTAGTGVSSITPNEWMVVAHEIGHGFGAIHDCNQQTCVGSPTANQCCPFSKTTCDAGARFIMNPSESTPTKLFSPCSIKAICSTISSSSGQCLKPPGTRSTQNAENNICGNGIKETGEECDCGSEEDCAKDPCCNGATCKLKAGAVCDDLNDGCCLNCQLRSAGQVCRKAVSVCDVQEVCTGTNATCPTDQFVANQTPCTGSGNVTGLQCANGICTSRDLQCQQQDRTGVNRQCGAAPNSCDLTCNDPSGSALSCVQIPGAYFVDGSPCGVGGTCQLGTCQYTEGVNGVVNWAKNHLAIAIPVISVLGLLFLCCVWSCCCAGCVRRRRYEQQVYKAQTGNEYAGFVPPQGNPPPQQYPMVPLGSMAPPPPAYQSGQHQDPNGFTNHPNGSNPNNPFGDHNAQDRNPFEQQHGRGGYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWN9</accession>
    <name>A0A9P6MWN9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_010034</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000657">
        <property type="protein sequence ID" value="KAG0015131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWN9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050562">
        <property type="entry name" value="FAD_mOase_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356:SF2">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356">
        <property type="entry name" value="FAD-DEPENDENT MONOOXYGENASE ASQG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="63"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="220"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="474"/>
            <end position="555"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0015131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="588" mass="65744" checksum="B5FBB6AF2D7088D4" modified="2023-09-13" version="1">MRDNRICWGVICQVESASASRDAMFRNSDWGSEGDEGVMHGAFDKTTPVGGTVRDLFEATPKENISKVFLEDKLFETWYYGRTVLIGDACHKFLPSAGQGAVNAMQDAVILANCIYEMGEATPENITAVFKEYYDERYEPVKKMMAKSRFMALVMYGTTFKERMFRHIIVNWVPSSTKFKQYLKDTVYRPQASFLDYVENHGTSEVLPQKPSRRYAEEKAVAKGSAMALDAKIMPVFEQLGLLDELLAISLPCKGINILDPELKLMTGLDFKDYKKRTGYEMAMFVRPRLHRLLLSHIPSEKVIFSKKVVSLEQNEQGVTLAMSDGTTVHGDILVGADGTYSGVRQGLFKNLDKEGLLPASDKEELSMGHLCMVGTTNPVDPEKYPCVSDDRALFQRVIEGGDPHTWHTVNVCDNKICWGIILQIDSAAASRDAMFRLSDWGSEGDEGVMSGAYDKVAPTGGLVRDLFDATPEEEISKVFLEEKLFKTWYHGRTVLIGDACHKFLPSAGQGAVNALQDAVILANCIYEMGEATPENITAAFKEYYNERYEPVKKMMAKSRFMALIMYGMVGAFLPFSDIEESEEAAIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWQ3</accession>
    <name>A0A9P6MWQ3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Vacuolar membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_009874</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000630">
        <property type="protein sequence ID" value="KAG0015428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWQ3"/>
    <dbReference type="OrthoDB" id="431202at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022127">
        <property type="entry name" value="STIMATE/YPL162C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31735">
        <property type="entry name" value="VACUOLAR MEMBRANE PROTEIN YPL162C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31735:SF1">
        <property type="entry name" value="VACUOLAR MEMBRANE PROTEIN YPL162C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12400">
        <property type="entry name" value="STIMATE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="25"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="66"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0015428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="149" mass="17508" checksum="0373B7DD3C30613D" modified="2023-09-13" version="1">MRIDGLKTGDYGNPPQFERWWKQTLVFSLGLVVMKIVVVVVLTWPFLFTFGEWFLGWTLQNEKLQIVFVMLILPLSMNICQYWVIDYILKQKTTEKFPIRMDEDEEDLYGLVGGLEQNYEEDEEDIDDHPDDSRNGREGTSHPSLTERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MY54</accession>
    <name>A0A9P6MY54_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">GDP-fucose protein O-fucosyltransferase 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_008769</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the glycosyltransferase 68 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000488">
        <property type="protein sequence ID" value="KAG0016926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MY54"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046922">
        <property type="term" value="F:peptide-O-fucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006004">
        <property type="term" value="P:fucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11296">
        <property type="entry name" value="O-FucT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019378">
        <property type="entry name" value="GDP-Fuc_O-FucTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045130">
        <property type="entry name" value="OFUT2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13398">
        <property type="entry name" value="GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13398:SF0">
        <property type="entry name" value="GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10250">
        <property type="entry name" value="O-FucT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0294">Fucose metabolism</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="95"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="148"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="152"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="163"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00026232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0016926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="550" mass="62843" checksum="D6DF50DE41FEE0AF" modified="2023-09-13" version="1">MSLLSKLPWKHGDLALLATSSAERWRTKRRVFMLFAIVLLVSSGSLLVLHLTTPRYTGSKDPYSSSSMIRWSSSRLKNDRWDSFGDFNDEEEEANDAYLSNNRGRARPRQALPSRRPISNDREQILMQQQLELQEGELKRLRELAQDRQKELLSQQSKQQGQATPNVDSNADHQQSPQLIGSKDDIILRESAMAPRPFEETLQGHDDVSYLTYLPYAGITNQFYGMLRGMEVAKALNRTLIIPPITSSSHDKSKQNQPWSKFLDLKQFSKVTGIKVVEFHELRDAELTLYNELKCRITCGFGSKRTIDFTAKGFLTQWRLNATLGPLPVDDGKLETILTTLEPLKNDKYICISNTYKIAVKDKSEWERFGQHLRFTSELEGFVQQFLNSNLIPARESELDPVTGKQTSPPRHRYIAIHVRRGDFAKYCENNFAGSKLIHCLPSTEQIGARVDLIQKRINPLMDPSKMLPVFVATNEQDPEELKKFANLGWQYLDHAKMGTVEALGVFGPMMVDQMFIAQAEAMIGIQMSTFSRVGALRQRDWEGREAEYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYF5</accession>
    <name>A0A9P6MYF5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_008708</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000482">
        <property type="protein sequence ID" value="KAG0016988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYF5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0016988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="107" mass="12337" checksum="DC560D5FA953FFB5" modified="2023-09-13" version="1">MTPFKNDPTIIISKITESAKTSEVPEFDALRSLIRVFGHHVHYNEFKEEDWFIHKMIIDSVWVGDYEGGRLSVKDYRSHVLDGTFDFVAAINTKVGMCLDSLQKLFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYM2</accession>
    <name>A0A9P6MYM2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008296</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000445">
        <property type="protein sequence ID" value="KAG0017426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYM2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="186"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0017426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="288" mass="32740" checksum="71D17B59718ECDD4" modified="2023-09-13" version="1" fragment="single">MTDWSKKHSAKQPLSWKAVIGEDQPGAGYFLSSEPGRFDPVEYFKSRGATSNRKEMLTFEWANWMTHFSNSNVKRLQDISIHLRSRNKLAQTQFWENIAYQERIQKQKQRLMDTRKLDLRKQNINQLRSDGVAMTRELDEELNVRVIESPVISVDTESSGIPKHDDLLQNFSDTSELKPGPSVSKTSVHSSDPTDSTTSSAIRSSYVRTAAPDLSKRKANAAGLRLPEPWRSLIETAKALHLGKNVDISPMPDISHLSTLRQSLFKCAYDNLRAFKSDRKLAIHQKDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYW0</accession>
    <name>A0A9P6MYW0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">U3 small nucleolar RNA-associated protein 10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">HEATR1</name>
        <name evidence="10" type="ORF">BGZ80_006366</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Involved in nucleolar processing of pre-18S ribosomal RNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the ribosomal small subunit (SSU) processome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
            <location evidence="1 8">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the HEATR1/UTP10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000314">
        <property type="protein sequence ID" value="KAG0019059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="31183at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034455">
        <property type="term" value="C:t-UTP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045943">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012954">
        <property type="entry name" value="BP28_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056473">
        <property type="entry name" value="HEAT_Utp10/HEAT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022125">
        <property type="entry name" value="U3snoRNP10_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040191">
        <property type="entry name" value="UTP10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13457">
        <property type="entry name" value="BAP28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13457:SF1">
        <property type="entry name" value="HEAT REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08146">
        <property type="entry name" value="BP28CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23243">
        <property type="entry name" value="HEAT_HEATR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12397">
        <property type="entry name" value="U3snoRNP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01036">
        <property type="entry name" value="BP28CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 8" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="5 8" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="BP28 C-terminal" evidence="9">
        <location>
            <begin position="1859"/>
            <end position="2038"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU367065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0019059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="2193" mass="245011" checksum="98567BDA23BCB8B3" modified="2023-09-13" version="1">MTSLAQQLKRIGTADATRGSEKAARHRASFLFDSKQAADYDIDTIFSIGANGIAELKQLDPKFQPFEKTLFAESMKSVDRVLQTKEDNAKLDESIALFLRQLSPYFLLKPAGKALEWLIRRFRIHEFNIDAILHAILPYHESAHFVTMVSILQIEESSRWMFLRPIRKSKQPLDRTLLIQYMLKDRSLVEFVCETVLQAVTRRSSYKTLISFYVAVMLQYISTLPVITDEVLTAIFPYILEGLKAKGTPDYQIATYMIISQISERATLTFEVISSLFISMTSNHSNASQMVLCLVHVCQTQETFDVFPERAFRTLCLIDGIETVILSILEKYSAQRFLHPFLIALAKHSSKHPNFARILNIILKEAPQPSSIVYGVCSAVLDLYLTESQQNETAEMNVDTLSILHVLHQNYSKDMDAALQSKLEESKGEERSKTHIQLYSFISKAFNGTRHQPLKESNTTLFLSVNHAEASIRLLAVKKLNEILKDKTSDLSNVDNEDTFVKDTLLARLQDDDERVVQQVLGMEALKQFVSPQNLLKGLLNVITAHSTTRGTRRHCLVYLLTVFLTNNKSLHDEVLAIVLGHMMLIKDFHKASIAVISNVSTSELKKDPLLKNVATAIKDLVKDDATVTPDAMIAANLTLVETLSANLVSHNNLSQGLDVYLEGLQGDNVAFRLLSIFVITKAVHQLNVEKQVKAINRYLPVLLRVLKTHSSATKALKAETRDALPSKTLLNQIVTKSWTPSTEVSAIRFSLLSVVTDLKKPAKTNVSWLSDGPLSEYATVVLSLYKTFVGTLRMGPYEQMIEKLFENHLMSDSIEFLCNLWTDSTATALIQLRSLQIANANLQAFATQTTEDAIDFQVVVPTLLIALANPAKAMRDTAVSCLQSIATLYPKVKITGKKGKSMATDIFKFDSFYGKTSDQLEFLMPEQISSFLTELLKSREEFITDGGYLAKYLSEHLNHVAGEPKTTASAKDSVISFILSHVLALTRTSSRVDLLQLLDNVNSPTKLKMLLPLVESFVHSTFVGQSSADDINTDFARLLVRCFSPETSSLLEGKSGKSGKYRNAFLQLLKLDNTAATNTDTEESSSSFRRLALGQINSRFFSGFNVSLQRDIFVVLVDLATNAPQETVRIVKQVLRDIPVSSDLVIYELATIQSSLMQETMVDEENSSKRQRKAPVDPSTPSAVVEALHRLVSVLELLEYKDVTESSKLVTPLFELLSTIMNSDLNNTPVSIEYINQLMLSSLTSFVRQADSGVNAGKLDESILRVDLVVNCIRATGNPQTHNQALLLMAAIASLYPEKVLHNIMLVFTFMGANVLRQDDNYSFHVIQQTLEKIIPPLVAAHRRQSAESQSLVLQVRPIIKVFVDALFHIPKHRRLRLFSVLITTLGEEDFLHAVTCLVIEKYTEKASKGHQTEADSLSEFALALSNQFSAIVQMKSVIALMDVIGALPNEKTEGGDVEMEEHLFDLSTHNSKQIRQFKLSVLTFSSNIMSSKSFLSKILTQTNTDSSAETVLESYYLQLAERILSLVGTFTAFVNVLAARKEPSLLVVKFWRGIVKVTYDVLDKVHILLSLPSFVKIMVALFEHKDVTIRRKAMGLFNQKISNVPGSPAAVPAVYENLVVGVSEDLKKAIETDQIEGATAEEVAINKQTALLCLSTIVRQFGASHPAEIVKIIPTIIGPSGLQHPNEQVKASCLVCLTFMSQELGVRVVPFLPKFMPVVLSILGGTLTSTNAAAAAAAEVDTKKSSRYNNSVLLQLAVVSHIETLVKVLPQFVSPYVTKILASTLHPVLAGYGGSDASKLQILEKNKRLLTEMAHHIQPRVLLPPVLGYYETATKDGKDSLLALFDLVSQTIQAMPRDVIALHYKQIFKFFLGAFDYRRASHEKADKESVATVAVVEDAVIEAFMKLVMKLNETLFKPLFLKTLDWATTELQVAKASFKDMQDRLIFFYKLLSSLLENLKSIVAPYYGYVVDNVIEALTGYAKKAKASSSYEDAGSDDDNETDGKDGVIKAREMDELWPWMVSSLQKCFLYDNDGLWNADRFEKLLHPLVDQLLVTVDVEEDEEDSEETTTTTAPDSTEWKSYENRINTWLVPCLGQLAVTLSNDALWKPLNYQVLLKTREDNKQIRLSALKALQEFYKRLGEEFLILLPETIPFLAELMEDDDHEVEALTQQVIADIEVYLGGSLQKYFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZE8</accession>
    <name>A0A9P6MZE8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_007349</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000374">
        <property type="protein sequence ID" value="KAG0018303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZE8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37331">
        <property type="entry name" value="YALI0F11671P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37331:SF1">
        <property type="entry name" value="YALI0F11671P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0018303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="214" mass="24532" checksum="DAE5C50962C388F2" modified="2023-09-13" version="1">MLSHTRTPFLSQFCRTRFSSRQPTLSSPLQRLAFIRFQSTQSQAIRDQSYPYPLYYHQLPQPSSSTTATSSSPDQPLSYAVSFLPTFPHHNYQIIGFLTHDKIGDLHATPNKFTENEAFNIVLHTVIQKNLDKDPVIQLLQPEGWTHIADYRNPAPHGRIPLPEDIFGSVQVIGGVIQPSTYQRMPTHRIVSRHGVFQLSEYLHEKLVNHLKTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZP9</accession>
    <name>A0A9P6MZP9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA-directed RNA polymerase III subunit RPC9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_007237</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic RPC9 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000367">
        <property type="protein sequence ID" value="KAG0018382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZP9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006384">
        <property type="term" value="P:transcription initiation at RNA polymerase III promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010997">
        <property type="entry name" value="HRDC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006590">
        <property type="entry name" value="RNA_pol_Rpb4/RPC9_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005574">
        <property type="entry name" value="Rpb4/RPC9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038324">
        <property type="entry name" value="Rpb4/RPC9_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038846">
        <property type="entry name" value="RPC9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15561">
        <property type="entry name" value="CALCITONIN GENE-RELATED PEPTIDE-RECEPTOR COMPONENT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15561:SF0">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03874">
        <property type="entry name" value="RNA_pol_Rpb4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00657">
        <property type="entry name" value="RPOL4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47819">
        <property type="entry name" value="HRDC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="RNA polymerase Rpb4/RPC9 core" evidence="8">
        <location>
            <begin position="1"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="137"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0018382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="156" mass="17588" checksum="8E57CA10309BB5C7" modified="2023-09-13" version="1" fragment="single">MEIIKADSAMLSNYEVLALLNDQKAQRQANEVAGTREVAENLRTIEFEVQKYLDASPCSTQTSDQVSALKKAFEGYEFMKVELLQILNLRPRTPVELVLVIEEFEQRFDMSDCKPMLAIIRKALPRADDKILASDLDMGDAEVEMDGGEGEQREEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZZ1</accession>
    <name>A0A9P6MZZ1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Methylenetetrahydrofolate reductase (NAD(P)H)</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_005046</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the methylenetetrahydrofolate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000251">
        <property type="protein sequence ID" value="KAG0019934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZZ1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004489">
        <property type="term" value="F:methylenetetrahydrofolate reductase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00537">
        <property type="entry name" value="MTHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029041">
        <property type="entry name" value="FAD-linked_oxidoreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003171">
        <property type="entry name" value="Mehydrof_redctse-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45754">
        <property type="entry name" value="METHYLENETETRAHYDROFOLATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45754:SF1">
        <property type="entry name" value="METHYLENETETRAHYDROFOLATE REDUCTASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02219">
        <property type="entry name" value="MTHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51730">
        <property type="entry name" value="FAD-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0019934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="151" mass="16938" checksum="8268EA58832A0E87" modified="2023-09-13" version="1" fragment="single">MKIVDRIAQKKAEGKPYYSFEYFPPKTSQGLSNLIDRIGRMQSMSPTFVTCTWGAGGSTFEKTTELCAVAQTVHGLETCMHLTCTNMDRGKVDDALKEAKNAGIQNILALRGDPPRGQEYWTQVDDTFVHAIDLVRYIRQQYGDYFCIGVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0J3</accession>
    <name>A0A9P6N0J3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005365</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000265">
        <property type="protein sequence ID" value="KAG0019717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0J3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013887">
        <property type="entry name" value="UPF0592"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37988">
        <property type="entry name" value="UPF0592 MEMBRANE PROTEIN C7D4.03C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37988:SF1">
        <property type="entry name" value="UPF0592 MEMBRANE PROTEIN C7D4.03C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08578">
        <property type="entry name" value="DUF1765"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="265"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="421"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="496"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="598"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="676"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="948"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="17"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="421"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="517"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="618"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="646"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="676"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="957"/>
            <end position="967"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0019717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1013" mass="108443" checksum="C4D25FD90CEC381C" modified="2023-09-13" version="1">MNPKPTTPSTGRTCIDGSGSVTEHTSSTTSVSSSTTLGSGYLFTDSSAFWSSFQQYRKMLTQSLQHAIEELNQKGVFSNVITFCAKILAVCFFKLPGVAFGLLHALPVSRSYIIRMAKAMGLTGEFEKQKHKMHSGEAPPPMEMYGNWVRRWQSDDSELFFAFYRHYHHCLAQYLELPLQRIQAGGWATSAIAPKVYAGAPGYLYLSAFFMTKIEGLVHREIHPVTTIVQAELNPVNGANEGDRAMASIATGEFPGSAAPPAVKLPGANGGADTGKDNANGGGPATGKPKVLEMASKRFVETIVAIMEDHGNIYGAMLDIWIKTAVTKTSVYDVESVFCLLDFLDMLIVELESSTVPTLEQLTLGTLLSPDVFEKCFLHWARNVRLYYMRCLVWRVAKIGGGVGILPGWKPWTPQTFSSTQGSAMSGMASSTGPNSDSTIKRTTTREALESLKGLPVEQSLSLIVRNIFEVMESRIDIVKRQYAGELNDVALPMTSGKGPEFLPESVPSSPTRSDHISSSASDSESISSAGERSPTALPFCQGSLSDGMTQDEENREKTRAFYQLQGQQICLSNQTLAGSDSGTVKVVSKDKPKKASLIGRKFRRLGRADSPAESPEWDSQQRGSFESDSTLYDPTVDNLVGSNGGSANKRASTGSMPLTAGSLFRWMFLGGQSNKLTSGDGNGRSSSDVYSERSEDRLQGSQHSLASFSSASSSASLALQMNNNDQGSDVYRHDGNDRSFYSPQLTPSLRYGLDLRKYPEHLNIYAARSIPEYTVVLNEYVEWLTQCRTYGIKSRVGNVANGPAMSAQNQGQSQLGGVPGIGLGPGINCAGDVEELFGRFSVFSLSVGSVVDASVVAGHQDEWISPGMAQMMMLRFPGLVTEWPKFWNNSRDASGPPPGPITTLPALAVVNNPVFSIGKGSAGGVSVGVGAGAGGAFGGASINGFGSGNGPSSLKHQQQAQMHHQQQTQLWSRNAAAAAAAAVAAAATASEDQQGIPMSNTIGSAPVAANKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N189</accession>
    <name>A0A9P6N189_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004790</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000240">
        <property type="protein sequence ID" value="KAG0020100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N189"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81995">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="7"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="276"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="408"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="518"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="47"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="276"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="294"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="333"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="358"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="413"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="518"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="563"/>
            <end position="579"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0020100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="579" mass="65426" checksum="D0E99A6A580B8905" modified="2023-09-13" version="1">MFTIFVVPTREISPSPSPSSCPHKSSKTIGNDTEKHPRCLQHRTRPRQPASAPRPSTHSLIDTLQNSIFFGGLGSLSREVEAMERQLAAEALVKASIKDKPLQLSSIPSGDPTSTLTVTTATSAPEQGLWSRISNMFQLETGAVPLKRYKVTVEELPDSVEQSSRSGKEAVVTTTTAVGQDNATLQPIEELPDMTSENSTIKNNLDAVHSAPLPSSPQNNQASSDVVADHDLSAAVAVSTAAIVASNAANANAQSTKSHEKEDVVSPVLVNKIKDTQETKSHATRENENDEILTETTEITQRNWPPRRRPLSRNESYTETIITRPDGTRESKTVTVNRETGASETHTRVEYADGSIKESVQSPNGSTWTTIRQRKQQQQQQQQQQQQQQQQQQQQAQVQEPATINTTEGDVELGSHRQSFRDRLAQRRQERAERRKEKQERRKELREAEARQREMTAAAYGFGPGSATTEDAGYDRNDIRVQESDKQRMNGEEDPHGARVEFHRFHDPHYRNIWHQRREERERMSEKQQQGERLRRDENGNGEDGEQVLYSKSRTWPPRGYLRRLEKEQEQEYEPRHNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1H9</accession>
    <name>A0A9P6N1H9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein 135 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001836</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000143">
        <property type="protein sequence ID" value="KAG0021718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1H9"/>
    <dbReference type="OrthoDB" id="291792at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026749">
        <property type="entry name" value="Tmem135"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12459:SF6">
        <property type="entry name" value="GB|AAD46013.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12459">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 135-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02466">
        <property type="entry name" value="Tim17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0021718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="512" mass="57409" checksum="C5C32B492B0CA0D2" modified="2023-09-13" version="1">MTLSTSSSFVSIDSNSDVDSPILTKSSKPLATTANENGATVPSKPSDSKIRKSSFSHRHEWPNGKRPKGFRTQEGKEAAEKAKAYKTSVSIPHLSAPCNTYEGVLKHAILGAIRSGGVTYGLKALVNLCLGMLKLMRGKGSFAQIFKDSFFGVDAIRFGSFFGAFSFLWKFVNNGLRLYRGKDDRLNGAIAGAIAGLSILIESHERRVTFAQTMLIRAGQGVYNAGKHRGVFSFRHGDALLFALACGQVMYAYTIQPQSIPPEYLKFMVNTARVPTEALAFNRLRVRGFPLDLHEVTDMVKRYKATPKALETVAELTEFAKIVPCAVIHPHVDSCRMNNFVRFWEVTRGILPVYATLNFVPLLVLRAKKLMADPVNVLSRVSFNTIRSSVFLAVFVVVYQSQICGHRNLVKYGWLNSNSKYFYWFFGFICSGTSIMVEQESRRAELAMYVLPKAAESLYKILYQKNWVKGVKHWDVMMFSVAMSLIMSFYQQEEQVLSPFVTKLIYHILGKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1K9</accession>
    <name>A0A9P6N1K9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_002284</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000156">
        <property type="protein sequence ID" value="KAG0021482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1K9"/>
    <dbReference type="OrthoDB" id="3257538at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="395"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="34"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0021482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="449" mass="49967" checksum="1ECF387FDE42F0F2" modified="2023-09-13" version="1">MTDVQPAPVAIEDPAVAEVVAATEQVALDDSQVAEHVHGPDCSHDHEHEHEQQQAAGQRHDFDLLEVNGTKDKTTDPLVKKYFESKELFAKAMERLNEIPEGGEAELVEKHKDEIASVTKDLMKAFLLDEKACQINQRILKLAEQYEVYVQTHNPEGTSTATAESEEEGAEQQTTIYTRDSVIFVIMILWSGGQFEHCIQTLTFAIQEFADLKGRLLELRSTCYMALRNFKACNEDLEEALTCEPVNVENHSTLGNVYYVTHQAQDALHHFKEFVAVAHPDSRTLPNAYYALSILTLQSAPTGATKKKSNQALKQAAALKEAQDYFKKAQEADLRFKELYGVVTGLNDIKRTAIGAFQIRTANRNGFMSTDPTPALLEASEILKKSFKSPGVSSCANCGRPDNVANEGRAPTSKPKPLLRCAKCNKVAYCSRPCQITHWNSTHKNNCKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1V1</accession>
    <name>A0A9P6N1V1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Vacuolar protein sorting-associated protein SNF8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">VPS22</name>
        <name evidence="3" type="ORF">BGZ80_003642</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SNF8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000198">
        <property type="protein sequence ID" value="KAG0020760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1V1"/>
    <dbReference type="OrthoDB" id="283883at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000814">
        <property type="term" value="C:ESCRT II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043328">
        <property type="term" value="P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016689">
        <property type="entry name" value="ESCRT-2_cplx_Snf8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040608">
        <property type="entry name" value="Snf8/Vps36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12806">
        <property type="entry name" value="EAP30 SUBUNIT OF ELL COMPLEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12806:SF0">
        <property type="entry name" value="VACUOLAR-SORTING PROTEIN SNF8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04157">
        <property type="entry name" value="EAP30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017215">
        <property type="entry name" value="ESCRT2_Vps22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="136"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="144"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0020760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="286" mass="32479" checksum="93D2B13721988049" modified="2023-09-13" version="1">MNRRRMQIGAMAYNERLKATNESYQRVGQTISDNQLEQLNSQLETFRANLENFARQHRKDIQKDPVFRMHFQKMCANIGVDPLASSKGFWGELLGVGDFYYELGIQIIDVCLSTRALNGGLMELSEVKRRVERMRGIRDNKAPSSTSSNTHSNNFSNKWTSISNKDTSMEVTEDDVLRAIKTLAPLGSGFQVLQIGDKKMVSSVPRELNRDQSAILALVRDTNGHVNPRLIYERLGWESGRIDTALDTLLEDGLMWIDKQAEPYEYWVPGFFDPEDDDIYAAAASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2J1</accession>
    <name>A0A9P6N2J1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Inhibitor of growth protein 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ING5</name>
        <name evidence="3" type="ORF">BGZ80_002437</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000160">
        <property type="protein sequence ID" value="KAG0021419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N2J1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16858">
        <property type="entry name" value="ING_ING3_Yng2p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028651">
        <property type="entry name" value="ING_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024610">
        <property type="entry name" value="ING_N_histone-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10333">
        <property type="entry name" value="INHIBITOR OF GROWTH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12998">
        <property type="entry name" value="ING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01408">
        <property type="entry name" value="ING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Inhibitor of growth protein N-terminal histone-binding" evidence="2">
        <location>
            <begin position="6"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0021419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="186" mass="20997" checksum="E5D02D6D5DFA9A15" modified="2023-09-13" version="1">MTAGEFLEEYIESLENLPSEVQQGLQELGKADAQYFELRENYRAHWKKYIKSAKRSSIPVGEDPALVAARLNIEKEYCAAIRKVDQKIDHSSKLYELINRQIVRLDEETQRLGIDLQDPGEVKKDRKSQKGPISAPRSSPNSRKRGSGAIATMDNIDPNEPLYCFCQQVSFGDMVGCDNDSVSTQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2L0</accession>
    <name>A0A9P6N2L0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_002536</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000163">
        <property type="protein sequence ID" value="KAG0021371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N2L0"/>
    <dbReference type="OrthoDB" id="5580488at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990756">
        <property type="term" value="F:ubiquitin-like ligase-substrate adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd22147">
        <property type="entry name" value="F-box_SpPof1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1280.50:FF:000016">
        <property type="entry name" value="E3 ubiquitin ligase complex SCF subunit sconB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000715">
        <property type="entry name" value="F-box protein MET30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051075">
        <property type="entry name" value="SCF_subunit_WD-repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19872">
        <property type="entry name" value="UBIQUITIN LIGASE SPECIFICITY FACTOR/HREP PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19872:SF9">
        <property type="entry name" value="UBIQUITIN-BINDING SDF UBIQUITIN LIGASE COMPLEX SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="1 4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="F-box" evidence="6">
        <location>
            <begin position="145"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="374"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="414"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="454"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="493"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="612"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="637"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="677"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="216"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="223"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="240"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="250"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="276"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="318"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0021371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="712" mass="79440" checksum="CDF767D9994383CB" modified="2023-09-13" version="1">MAYDSPSPTSESLAPSLCLNPDALEDLAPVQPTEENLLPSSFPTLTWSEQSSADHRAAKAEKRLCYRHRPDLRSKRAADEIQLDQLQQDIKRLPQQDQQIISHIWSLFGSAPASHRQLVLSGLLTQCCVPQLSFLSNHLQPLLRIDFLSITPPEIAFRILSYLDATSLCHAAQVCKSWKRLADDDVVWHRMCEQHIGLKCTKCGWGLPLLEKKKVRSKRQSEQQHQQQIQQHHQQQQIQYHNASQSSGAESDHEEHDHSTSRPTVAPSHPSPPASTPSLSPTETTPSVGWPSRRRSASNDEDIETDRSQKRIRHDSRSPSPSTSTKPTTPLFQSPEPPVKPTEVVAKRPWKEIYSERLIVERNWRKRNYRVKVFKGHTDGVMCLQFDDSFLITGSYDNTVRIWNIETGECLRTLTGHALCVRALHFDDAKLITGSMDRTLKIWNYHTGQCIRTLQGHTDGVVTLDFDSRILASGSADATVKIWNFATGECSTLKGHCDLVNKVQIYKKKLLVSASDDTTVKLWDIATRTCLRTFTGHVGRVQCLQTSGDALISIIAEQVRKKSQNGSSSQGRSQGGVPTTVCSINRSGVVENALPSPSQDANSDTEKRNMMSIIVTGGLDNTLKIWDVETGECLNTLFGHVEGVWSLAFDKLRIVSGSLDRTIKVWDTESGRCLYTLVGHEGPVTCVGLGDTRIVSGSDDGVVYVWNYGVRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3B6</accession>
    <name>A0A9P6N3B6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FK506-binding protein</fullName>
            <ecNumber evidence="5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">FPR4_1</name>
        <name evidence="9" type="ORF">BGZ80_000654</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FKBP-type PPIase family. FKBP3/4 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="5"/>
    <dbReference type="EMBL" id="JAAAID010000114">
        <property type="protein sequence ID" value="KAG0022257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3B6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.50.40:FF:000006">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.340">
        <property type="entry name" value="Nucleoplasmin core domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041232">
        <property type="entry name" value="NPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023566">
        <property type="entry name" value="PPIase_Fpr3/Fpr4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43811:SF19">
        <property type="entry name" value="39 KDA FK506-BINDING NUCLEAR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43811">
        <property type="entry name" value="FKBP-TYPE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17800">
        <property type="entry name" value="NPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001473">
        <property type="entry name" value="FK506-bp_FPR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="8">
        <location>
            <begin position="292"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="136"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="387"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="136"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="176"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="242"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR001473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0022257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="412" mass="46101" checksum="2935B3082F3730E6" modified="2023-09-13" version="1">MILGFWGLTVFPEKTYTQVVDSSFKLSMAALDEEAKPGRSSIRVTVDKKTFILCSLITGQVEQQKLDLIFTEGEEIVFSVSGENAVHLSGNYLPDDGGDYDDDEDMYGDEIEEDEEDEYDEGTSTQGIKNIIDYVGNEEEDEDSEEDPDFTGEDEDEDDEDSDEEDDDNVNNQEDNVCEDDEDEDEEGDDEEDVEDEDEDEDKDEDEDEDEEEDGGDIEDVIAKNQAAKKQKVSSEKAIPTKSKEEPARKEEPKRKEEPKKKEEPKNNIKTLPSGLIIEDIKAGDGARAKVGKKIGMRYIGRLSNGKVFDKNTGGKPFTFKLGSGEVIKGWDIGLQGMQLNGERRLTIPPALAYGSQGAPPDIPRNATLVFEVKLVEIYIDERRTKTKEKTTKARLTTAKKQSKATEAIIKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3E0</accession>
    <name>A0A9P6N3E0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HTH CENPB-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_008096</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000043">
        <property type="protein sequence ID" value="KAG0023769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3E0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042729">
        <property type="term" value="C:DASH complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072686">
        <property type="term" value="C:mitotic spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008608">
        <property type="term" value="P:attachment of spindle microtubules to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013959">
        <property type="entry name" value="DASH_Dad4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006600">
        <property type="entry name" value="HTH_CenpB_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08650">
        <property type="entry name" value="DASH_Dad4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03221">
        <property type="entry name" value="HTH_Tnp_Tc5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51253">
        <property type="entry name" value="HTH_CENPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH CENPB-type" evidence="3">
        <location>
            <begin position="171"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="73"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="263"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="441"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="73"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="118"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="147"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="269"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="293"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="444"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0023769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="526" mass="59122" checksum="8B78AF34E1C028C9" modified="2023-09-13" version="1">MGVCGEKHTSLTREQKRQLIHQADTHKLRPTEVCDWVQATWGLRIARVTVYSILHKQRASLMAGHKDLYQTMQNSLNGSSSDPQSLTDSNTDVSGQKGNKDSGRVNKYRSSPVKNKNKVKENTKNVNDAKIDSLNATNNDSKRDRSGSVVSDRSSSSVDGSNAEGARWEGQLKRVREPASVELDRAMVEFLKSPASVDSQGRRLNDAELQAHALRLAQSIPSASRMRCSFGWLRHFKRRLGVQWAADKLGRYRWTVEMDPHQLEGSYPGSPSNSAKQELSNDVSDDEEEYHSTNEFGSDGRNSPLSPSPTKANQDNAQPQNIENSYANLFGTLPALHVPTSDSSMGTISPLATTLDPKLTSTTFSQPASTAASTYGMSVDGRMRKVPTKEEAYDMLQSLLMYYEQDHTYTGEQQTLLLPRWIHQQRQLMQQSPEVEAKMMWMRQQHQQHQQSQQLPYQRTASSSSQQNRAQRRNEKLNESLEQLNEKLARVNQQNQSTVLIAQVWNSYSKSVNIMLEGLGGLQPPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3T3</accession>
    <name>A0A9P6N3T3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_005474</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Endomembrane system</location>
            <topology evidence="5">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000027">
        <property type="protein sequence ID" value="KAG0024168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3T3"/>
    <dbReference type="OrthoDB" id="413400at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052606">
        <property type="entry name" value="DnaJ_domain_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44653">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44653:SF2">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0732">Signal</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040361252" description="J domain-containing protein" evidence="8">
        <location>
            <begin position="23"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="9">
        <location>
            <begin position="46"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="284"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="304"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0024168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="352" mass="40545" checksum="FB1A5A59AD4B0EF9" modified="2023-09-13" version="1">MRWNLVLLMVLALLALAQQVAAWEEGDFEIFDLVDALEKAEGSDVNFYSWMGVTQKTPKNEIERAFRKMSRTLHPDKNKGPKAQEKYARLSSIISILRDDAKRERYNFFLKNGVPRWRGSAYLYRRHRPGLKAVMVFLVILASGFQYLARYVGYIQERRRMSGMIEQYKEMLREKHQKVLEGPITGRQRRAGATPEAVTPLEEGPMYAVNQYGEEIELTLDNIHPPKVKDVVIFRFPFWIVKASLLIAPKSVREAVLAMDIFESIRPKDEQEEADAKRKLRKAELARKRAAKRAAQQKQSPNVSEDDEPYHSSEEDEEALAARAKEEELAAARRRRRMKAPGQATLKGGRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3V7</accession>
    <name>A0A9P6N3V7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RlpA-like protein double-psi beta-barrel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_005250</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000026">
        <property type="protein sequence ID" value="KAG0024212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3V7"/>
    <dbReference type="OrthoDB" id="623670at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22191">
        <property type="entry name" value="DPBB_RlpA_EXP_N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051477">
        <property type="entry name" value="Expansin_CellWall"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009009">
        <property type="entry name" value="RlpA-like_DPBB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836:SF22">
        <property type="entry name" value="RLPA-LIKE PROTEIN DOUBLE-PSI BETA-BARREL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03330">
        <property type="entry name" value="DPBB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="Barwin-like endoglucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040129925" description="RlpA-like protein double-psi beta-barrel domain-containing protein" evidence="2">
        <location>
            <begin position="25"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="RlpA-like protein double-psi beta-barrel" evidence="3">
        <location>
            <begin position="67"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0024212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="154" mass="16639" checksum="70CCC827F43A04D9" modified="2023-09-13" version="1">MRFSHLSILVIVAILAILTATAEAGQQVKIGKKQGGKSTWFNGHDLKGAACYGDLQNKNVNAKDNWHIGAVHMKSYSKGEKNVCFQCAKITANKRSVVVRIIDDCAGCSSTQIDLTASAFKVLAPLSKGVVKTTYQWVKCPSGGKFWPSSPKPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4V1</accession>
    <name>A0A9P6N4V1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="20">DNA polymerase</fullName>
            <ecNumber evidence="20">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="25" type="primary">POL3</name>
        <name evidence="25" type="ORF">BGZ80_008917</name>
    </gene>
    <organism evidence="25 26">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="25" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="25">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="19 20">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 20">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 20">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 20">Belongs to the DNA polymerase type-B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="25">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="20"/>
    <dbReference type="EMBL" id="JAAAID010000050">
        <property type="protein sequence ID" value="KAG0023592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N4V1"/>
    <dbReference type="OrthoDB" id="2414538at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043625">
        <property type="term" value="C:delta DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008296">
        <property type="term" value="F:3'-5'-DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006287">
        <property type="term" value="P:base-excision repair, gap-filling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045004">
        <property type="term" value="P:DNA replication proofreading"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006297">
        <property type="term" value="P:nucleotide-excision repair, DNA gap filling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05777">
        <property type="entry name" value="DNA_polB_delta_exo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05533">
        <property type="entry name" value="POLBc_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.132.60:FF:000001">
        <property type="entry name" value="DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.690:FF:000001">
        <property type="entry name" value="DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000351">
        <property type="entry name" value="DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.60">
        <property type="entry name" value="DNA polymerase family B, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.342.10">
        <property type="entry name" value="DNA Polymerase, chain B, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.690">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1600.10">
        <property type="entry name" value="Palm domain of DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006172">
        <property type="entry name" value="DNA-dir_DNA_pol_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017964">
        <property type="entry name" value="DNA-dir_DNA_pol_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006133">
        <property type="entry name" value="DNA-dir_DNA_pol_B_exonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006134">
        <property type="entry name" value="DNA-dir_DNA_pol_B_multi_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042087">
        <property type="entry name" value="DNA_pol_B_thumb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023211">
        <property type="entry name" value="DNA_pol_palm_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050240">
        <property type="entry name" value="DNA_pol_type-B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056435">
        <property type="entry name" value="DPOD/Z_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025687">
        <property type="entry name" value="Znf-C4pol"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00592">
        <property type="entry name" value="pol2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10322">
        <property type="entry name" value="DNA POLYMERASE CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10322:SF23">
        <property type="entry name" value="DNA POLYMERASE DELTA CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00136">
        <property type="entry name" value="DNA_pol_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03104">
        <property type="entry name" value="DNA_pol_B_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24055">
        <property type="entry name" value="POL3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14260">
        <property type="entry name" value="zf-C4pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00106">
        <property type="entry name" value="DNAPOLB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00486">
        <property type="entry name" value="POLBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00116">
        <property type="entry name" value="DNA_POLYMERASE_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 20" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7 20" id="KW-0235">DNA replication</keyword>
    <keyword evidence="17 20" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="14 20 25" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="13" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="15 20" id="KW-0408">Iron</keyword>
    <keyword evidence="16 20" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9 20" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6 20" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="18 20" id="KW-0539">Nucleus</keyword>
    <keyword evidence="26" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 20" id="KW-0808">Transferase</keyword>
    <keyword evidence="12 20" id="KW-0862">Zinc</keyword>
    <keyword evidence="10 20" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DNA polymerase delta/zeta catalytic subunit N-terminal" evidence="24">
        <location>
            <begin position="103"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed DNA polymerase family B exonuclease" evidence="22">
        <location>
            <begin position="193"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed DNA polymerase family B multifunctional" evidence="21">
        <location>
            <begin position="491"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="domain" description="C4-type zinc-finger of DNA polymerase delta" evidence="23">
        <location>
            <begin position="959"/>
            <end position="1030"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00049244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="RuleBase" id="RU000442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF00136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF03104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="Pfam" id="PF14260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="Pfam" id="PF24055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="EMBL" id="KAG0023592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1050" mass="118851" checksum="245A18A052FF64CA" modified="2023-09-13" version="1">MSQDAHAAKKRRISSNRTALMESQPSFLEDLELLQEMNQAAKVDDPSLLWARPTCNKINPSTDTIVFQQIEADEYMHSGMQTPVVRFYGITETGNSVICHVTGFLPYFYVPAPVGFKIENIPAFKTALETAIEKGNSIVKIEWKLKESIFGYHGGEKSPFLKITLKDPKNIAAAKRSIERGISFAGFSDFTGQTYESNIAYLLRFMIDCRVKGANWIELPAGTYQVKNDQNSNAQINIETSYDKIISHQPEGEWSKIAPLRIMSFDIECAGRKGIFPEAKIDPVIQIASMVTVQGESKPFIRNVMVLNTCAHIVGTHTMSFDQEEKLLASWADFVRRVDPDVVIGYNTSNFDFPYLLDRAKHLGVNKFPFLGRLNDVRTEAKDTKFSSKAYGSRENKAINMEGRLQLDMLQVMQRDYKLRSYTLNSVCAEFLGEQKEDVHHSIITELQNGNEETRRRLAIYCLKDAYLPQRLMDKLMCLINYIEMARVTGVPFNYLLARGQQIKVVSQLFRKALEKDFVIPAVNSQGGEDQYEGATVIEPNKGYYDVPIATLDFASLYPSIMMAHNLCYTTLLTPSTIQKYNLVRDVDYVVTPNNDSFVKESRRKGLLPIILTDLLDARKRAKADLKKETDPFKRAVLDGRQLALKVSANSVYGFTGATVGKLPCLQISSSVTAYGRVMIEKTKQEVESRFTVENGYEHTAEVIYGDTDSVMVKFGVKELEKAMKLGREAAELVTTKFDKPIKLEFEKVYFPYLLINKKRYAGLYWTKPEKYDKMDTKGIETVRRDNCRLVQSVIDTCLRKILIERDVVGAQEYTKQIIADLLQNKIDMAQLVITKALSKTDYANKQAHVELAERMKQRDAGSAPALGDRVAYVIVKGGKGVAAYDKSEDPLYVLEKNIPIDTKYYLDNQLSKPLLRIFEPILGDKAESLLAGDHTRTIQVSTPSIGGLMKFAVKTATCLGCKTPLKKDESAVCSNCKGRAPELYQKQRNIVNNLEVRFSRLWTQCQRCQGSLHQDVLCTSKDCPIFYMRKKVQKEIQDSSATLDRFVDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N6E0</accession>
    <name>A0A9P6N6E0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Tyrosine-protein phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_004278</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000022">
        <property type="protein sequence ID" value="KAG0024316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N6E0"/>
    <dbReference type="OrthoDB" id="6375174at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17663">
        <property type="entry name" value="PFA-DSP_Oca6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.190.10:FF:000084">
        <property type="entry name" value="Tyrosine phospatase-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004861">
        <property type="entry name" value="Siw14-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31126">
        <property type="entry name" value="TYROSINE-PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31126:SF14">
        <property type="entry name" value="TYROSINE-PROTEIN PHOSPHATASE OCA6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03162">
        <property type="entry name" value="Y_phosphatase2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="2">
        <location>
            <begin position="15"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="217"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="361"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="253"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="294"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="368"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="443"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0024316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="498" mass="52561" checksum="128959CC2E9AC460" modified="2023-09-13" version="1">MPASWSPTPLIPPFRFGTVEPEVYRGAYPKQRNLRFLKRLKLRTILSLIPDAPDAIFQEFCTQQGIKSIHLPVDKVKDNVPLTYNRAVEAVQIIIDRENLPIYIHCLDGASVTGLVVCCLRKLQTWNISSAMGEFLRYLRGGVISSEESVFVEKFCSEIEISKPIPLWLWEGQITFKKHPTLKLKFTIPPTPATPSVINTSIPSPTLPNQNVATVFPSHQGDGSGVARISTGAAINGGDTSTHGVNGDSSAISNLSNNNQSGPGSSLLSPSMALQNHASRLLTKGSPSRDRPNSNKTSVRTDISGLSSYGPRATSIATPTTAALPPNKRFMAGNSSILGQQQHQLSSQDQAPSDSMALAAEAGTALKSSSQSSLSSSGPSSSSGQATSEASETARAHVISIVRSRRGSLSTQSGEHGLDSVDNANTGKDGGSNVGPGLEENNADSLTSAAQDRNASGPAIAKNVSTAAPTPAPAAEVADEYYEVSMTLKALALEGADF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N7E4</accession>
    <name>A0A9P6N7E4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003697</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000002">
        <property type="protein sequence ID" value="KAG0024838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N7E4"/>
    <dbReference type="OrthoDB" id="2448942at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="315"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="317"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0024838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="336" mass="36872" checksum="CA64FD110B48CCDD" modified="2023-09-13" version="1">MDIENPYYQGSHSIHRPTSFPGTTIVASQPMQIDSPSTKRFSESQADFYSVASADSWVPTSPTATFSTTSSTVVASPTNQTYGSLSAHNFPPTQESLPAYNSTPMLIPQQLSKQDKHADKNGLGAHHSSISPGQRDSDNHPRCYQQQREFSPDLPLIGTSPEAKEWLKQKPTRSTTRLIHQYNFQNYQHYQPSRNPTITGYNARTISNNLNAPVLSINPKHGMVSTPNGHSDPSTQTPFKQKPGCITIAATTIASNDASTAQPWTCQDSPVPTRFTQKHFDGHFYHHGRDLSPSPPLSHNLSQEILGKEPHLVMSRSKISSHSTTTVPDGSPGSVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SQM2</accession>
    <name>A0A9P6SQM2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AMP-dependent synthetase/ligase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_009192</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010005293">
        <property type="protein sequence ID" value="KAF9991359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SQM2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043041">
        <property type="term" value="P:amino acid activation for nonribosomal peptide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.980">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020459">
        <property type="entry name" value="AMP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF1">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00154">
        <property type="entry name" value="AMPBINDING"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="1">
        <location>
            <begin position="25"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9991359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="89" mass="9631" checksum="2EC9143F4B556E9A" modified="2023-09-13" version="1" fragment="single">MIVPALIQTQVFCIKDYPVGDMDEKVFSMDAGDTAYVMYTSGSTGLPKGVMVPHRAIARLVINNGYALLDGNDRVAFVNNPSFDPSTSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SRN0</accession>
    <name>A0A9P6SRN0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Condensation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007775</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004034">
        <property type="protein sequence ID" value="KAF9994579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SRN0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043041">
        <property type="term" value="P:amino acid activation for nonribosomal peptide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19544">
        <property type="entry name" value="E-C_NRPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensation_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF1">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Condensation" evidence="1">
        <location>
            <begin position="31"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9994579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="419" mass="46243" checksum="D25ECE4A3618EE69" modified="2023-09-13" version="1" fragment="single">ITPDLLPLIDITQEDIDLIVSKVDGGVANVKDVYALSPLQEGILFHHTMATIGDPYLIVIRMSFRCKEILDRYLDAVQNVVDRHDILRTSIMWENLSTSAQVVLRHATLSVTELSLDPRNGSIPDQMTKLTDPREHRIDLSQAPLIRYVIAQDIDGSWVVVQLLHHTIGDHSTLEVMEHEIQAFFEGNGESLPPSEPFRNLIAQARSGPSVEVHEQFFTKMLADIDTPSLPYGLSDVHGEGFDVTETHIMLPQDLNDKLRGHAKRMGVSLASMCHLAWAQVISKISGQEQVVFGTVLLGRMQGGSGSDRAMGLFINTLPLRIDVGDTPLEESLRQVQSDLAALLDHEHASLAFAQRCSGVPPGTPLFSAMLNYRHNSESSHATSPILGVSITDGQERTNYPFTMSVEDFSTELGLTSQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SS92</accession>
    <name>A0A9P6SS92_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_007210</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003651">
        <property type="protein sequence ID" value="KAF9996591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SS92"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9996591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="71" mass="7990" checksum="4FEBBA9F083378EC" modified="2023-09-13" version="1" fragment="single">FGELLDAGRKVDSVFMFDGIELPDIGVKFQNASPRGVSIQLRKNVRLTRCIQELHLSFRMNEAPVVMGDVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SSU8</accession>
    <name>A0A9P6SSU8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">OTU domain-containing protein 6A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">OTUD6A</name>
        <name evidence="3" type="ORF">BGZ80_007076</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003561">
        <property type="protein sequence ID" value="KAF9997132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SSU8"/>
    <dbReference type="OrthoDB" id="415023at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22748">
        <property type="entry name" value="OTU_OTUD6-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003323">
        <property type="entry name" value="OTU_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050704">
        <property type="entry name" value="Peptidase_C85-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12419:SF10">
        <property type="entry name" value="DEUBIQUITINASE OTUD6B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12419">
        <property type="entry name" value="OTU DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02338">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50802">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OTU" evidence="2">
        <location>
            <begin position="193"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="134"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9997132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="276" mass="31222" checksum="52AF2BA6C8D1CF6B" modified="2023-09-13" version="1" fragment="single">MDQTTSTHQHESSTVEVQQPSSTTAGPSPEASETYEELKARHKKEQRDLTAKVTALKKTATKGDKKKKKEVTAEVAQLEHSLAQQQEKEEKEWINLHGSTDTQAKPEEEEEEEDDFDVNDIPIDHLTIEPVFAKKQQQPSGGKKPNRQKARKDRKAQALKELQDEAEKEAAGQVNMNEVERKAIEELAQVMGVSVKDITPDGHCLYNAVADQLSQHYQIKTTVKDLRHSTAEYMRRNSDDFLPFLSNKQGDMMSPDDFSEYCKELETTAVWGGQPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SSX1</accession>
    <name>A0A9P6SSX1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_006653</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003297">
        <property type="protein sequence ID" value="KAF9999019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SSX1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9999019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="128" mass="14224" checksum="8AE9F4952A2E1B14" modified="2023-09-13" version="1" fragment="single">ASAWKDAMINRIGQVQHGREVSLMMSNIGVGWKRPVPTSSQLLVKDGIFSSSPIKTYGALNMCIATVNGILSVVMAWDKAAFKERARAELFVSEFKRILLEAVEDGRETYLFKDAKRPYDDNTTAIAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SUU3</accession>
    <name>A0A9P6SUU3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Carrier domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_005333</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the NRP synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002637">
        <property type="protein sequence ID" value="KAG0006193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SUU3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043041">
        <property type="term" value="P:amino acid activation for nonribosomal peptide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05930">
        <property type="entry name" value="A_NRPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19544">
        <property type="entry name" value="E-C_NRPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.30:FF:000010">
        <property type="entry name" value="Enterobactin synthetase component F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12780:FF:000012">
        <property type="entry name" value="Non-ribosomal peptide synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.980:FF:000001">
        <property type="entry name" value="Non-ribosomal peptide synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.38.10:FF:000001">
        <property type="entry name" value="Non-ribosomal peptide synthetase PvdI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1200.10:FF:000005">
        <property type="entry name" value="Nonribosomal peptide synthetase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.980">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.38.10">
        <property type="entry name" value="Luciferase, Domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF1">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="1045"/>
            <end position="1119"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0006193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1262" mass="138747" checksum="878253EBA05E4348" modified="2023-09-13" version="1" fragment="single">MLGGHSLLAVQVIGRLRYIGMETSVRALFETPTLSSLAQSIAKSQTVTEVPKNLITTEVTRISPELLPLIDMTQHDIDLIVSKVDGGVNNIQDIYALSPLQEGILFHHTMATIGDPYLIVTRMEFDDKNILDRYLDAVQNVIDRHDILRTAIMWENLSTPAQVVLRHATLSITELSLDIKDGSISDQIMKHTDPRKHRIDLTQAPLIQYVIARGGGNSWIVVQLLHHIIGDNSTMSVMADETHAIINGQAQTLLEPQPFRNLIAQVRSGPGAEFHEGFFTKMLADIDTPALPYGLSNVHDEGLDVTESTLMLSQDLNARLRNHAKKLGVSLATMCHLAWAQVISKTSGQEQVVFGTVLLGRMQGGSGSDRAMGLFINTLPFRIDVNDTPLEGSLRQVQIDLAALLDHEHASLAFAQRCSGIPAGTHIFSAILNCRNHASQSRDALEVSGMKILDGQMRTNYPFTMSVDDFGTEMELTSQVVSSIDASRVCEYMQEALQSLVDALDHAPKMQVRDLEILPVAEREILIQSWNNTITAYPEHLCVHQLFENQVNQSPNSIAVVYEGQELTYRDLNSRANGLAHHLIDLGVKPDSLVAICVDRSLTMVTSIMAVLKAGGAYVPLDPTFASERLHNILTDASPSIMLADDAGIKALGSSISNLMEVINPNSFVCMHTTNPNVPALTSHHLAYVIYTSGSTGKPKGVMLEHKGVTNLALTRPCVFGVDSSSKVLQFFSFSFDGSVHEIWSALCFGGSLHVLSDRTRLDQSLLWNYLSDHSITQVTLTPSVLQDCKNLPVLNNKMTLLLAGEALPLALLQTLRVLIPNGTVINDYGPTETTVDAVGWKCPDDFSGDIAPIGRPNPNKRIYILDSNKKPVPIGVAGELYVSGAGIARGYLNRPDLTAKAFVLDPFTDDGSRMYKTGDLVRYLPDGNVSFIGRNDHQVKIRGYRIELGEIETRLADHPLVREAVVLALGEGSSKRLVAYVVAEPTEGLAHTLRAHISSKLPDYMVPAAYVRLDILPLTSNGKLDHRALPEPDMDSFVSQGYEAPQGETESNLAMIWAEVLKIDRVGRHDNFFMLGGHSLLAVQVIGRLRYIGMETSVRALFETPTLSSLAQSIAKSQTVTEVPKNLITTEVTRISPELLPLIDMTQHDIDLIVSKVDGGVNNIQDIYALSPLQDGILFHHMMATIGDPYLIAIRMSFDSKDILDRYLDAVQNVVDRHDILRTSVMWENLSIPTQVVLRHTVLSVTELSLDPMNGPIMDQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SVB4</accession>
    <name>A0A9P6SVB4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Rsc complex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BGZ80_005173</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002569">
        <property type="protein sequence ID" value="KAG0006693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SVB4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016586">
        <property type="term" value="C:RSC-type complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001025">
        <property type="entry name" value="BAH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043151">
        <property type="entry name" value="BAH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018359">
        <property type="entry name" value="Bromodomain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037382">
        <property type="entry name" value="Rsc/polybromo"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16062:SF19">
        <property type="entry name" value="PROTEIN POLYBROMO-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16062">
        <property type="entry name" value="SWI/SNF-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01426">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00439">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51038">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00633">
        <property type="entry name" value="BROMODOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 8" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="3" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Bromo" evidence="10">
        <location>
            <begin position="40"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="Bromo" evidence="10">
        <location>
            <begin position="161"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="BAH" evidence="11">
        <location>
            <begin position="273"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="427"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="527"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="438"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="537"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="551"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="597"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="609"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="656"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0006693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="656" mass="74523" checksum="A16B749245E4D581" modified="2023-09-13" version="1" fragment="single">MPPKRHGEGSVSIIEGISLKDKREAMSQILDRLENFTDKSGRLISELFLELPDREEYPDYYLTIKNPIAFDIIRDKLDSGLYDNENIVNFSKDLLTLTSNAKEYNRKGSPIHRDAMTLEAQIELAMQFLLEDGSQQDEQEPFTTEFCHRVLKTIKNHKDESGRLMSELFLELPSHEEYPDYYEEITRPIALDGIKKKINSGAYKNLESFEDDFELMFENAKQYNAEGSDVYLDAEELQQLFWKEIGKDGRGNTKNKHARKHVKELTQVSLHGGIFKVGDFVHLKNDRDPSKPIIALIFSLWEDENGQTGLDATWFLRPDQIVHPYASRFYPSEVLKASGSHEHLVSEIQDKCYVLYTRDYVRGRPIEWNQNQSIYLCEQRYNEAYKSVSKIKNWASCLPPGHKPSDMKLNLFPEPLVLKKLPSASMVDKAGRHDSEGPSRSSTPQDTSSRASAGGHKRNSLNQHPGSPPMAMTHQAQQVAPHHWVRCNYSSLSTGLQCSGVFPNQAELQRHVATEHALIQHVAAPPAMKRGRPRKNPLPATAATPTPGATQVSAPQQPMMNQQGAYPQQSFNPYNPAGQFGVPPRPGMPGQVMQPNMPYPQQPQPQPQPQAMHHMQQQQQQQQQRGMPYQQPFSQPLQQGQPRPQAYPQNVPYGQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SVD9</accession>
    <name>A0A9P6SVD9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATP-dependent RNA helicase ddx49</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">DDX49</name>
        <name evidence="2" type="ORF">BGZ80_005290</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002612">
        <property type="protein sequence ID" value="KAG0006449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SVD9"/>
    <dbReference type="OrthoDB" id="2327265at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040327323" evidence="1">
        <location>
            <begin position="22"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0006449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="274" mass="31236" checksum="A42BC31FF75C8EE8" modified="2023-09-13" version="1" fragment="single">MARHRLPFLVALVCISLLIIAYVARLQRRSCTPADAACVVYRPHIQLAIITSYYKSEYPDRAAEIDVSLASLIANPLLHQVHVLVEVKDRPLPPFAIVNPRTKEIVISKRPLMGDYIQYACDHLHETGHRVIFSNSDIFFDSTLDYFTKIADEVFDQTFYAISRWRLDATGKDIDTGAPGTPLGMTAYPFPTYGSYDTFAFKPKTICSDKVKLKDMVESLNYTMGVLGAENRLLYEVRRQYPEIKLVNPYKDVRTVHIHDSGRRGSTWSDRVNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SVF1</accession>
    <name>A0A9P6SVF1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Single-stranded DNA binding protein Ssb-like OB fold domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_005080</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002523">
        <property type="protein sequence ID" value="KAG0006963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SVF1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048970">
        <property type="entry name" value="OB_Ssb-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21473">
        <property type="entry name" value="OB_Ssb-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Single-stranded DNA binding protein Ssb-like OB fold" evidence="2">
        <location>
            <begin position="37"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="144"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF21473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0006963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="199" mass="21270" checksum="5C742B8C38E1FC31" modified="2023-09-13" version="1">MIHQFVNVASLVPDQRHCNLELRVLSVETIAETVHPENQVNLLARNARLRVLNAHVNMYRGFMRLEVNEDDEGGADGRGKPSITAISDDEDRDEDESVVASSSTTGNNSHAAPVSPGANMFGASGAATMPAAVSSSMSTATIASGSSSHSPMSSPSPSLPSRDQLEVEMRLGTGGSVPLMEYYRTIEFTYFSTVEPVGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SVK7</accession>
    <name>A0A9P6SVK7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">70-kilodalton heat shock protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">HSP70_5</name>
        <name evidence="3" type="ORF">BGZ80_004998</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002494">
        <property type="protein sequence ID" value="KAG0007154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SVK7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.30.30:FF:000001">
        <property type="entry name" value="heat shock 70 kDa protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000026">
        <property type="entry name" value="Heat shock protein 70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0346">Stress response</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0007154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="218" mass="24018" checksum="5ECC06879D7D09A9" modified="2023-09-13" version="1" fragment="single">MATGKAVGIDLGTTYSCVAVWQNDRVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNTVFDAKRLIGRRFDDKDVQSDMKHWPFKVIEKATKPYIQVEYKGEKKEFTPEEISSMVLLKMRETAEAYLGTSVTNAVVTVPAYFNDSQRQATKDAGMIAGMNVLRIINEPTAAAIAYGLDKKTTGEKNVLIFDLGGGTFDVSLLTIEDGIFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SW60</accession>
    <name>A0A9P6SW60_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003991</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002090">
        <property type="protein sequence ID" value="KAG0007990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SW60"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043743">
        <property type="term" value="F:LPPG:FO 2-phospho-L-lactate transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10680">
        <property type="entry name" value="CofD-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002882">
        <property type="entry name" value="CofD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038136">
        <property type="entry name" value="CofD-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31240">
        <property type="entry name" value="MATERNAL EFFECT EMBRYO ARREST 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31240:SF0">
        <property type="entry name" value="MATERNAL EFFECT EMBRYO ARREST 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01933">
        <property type="entry name" value="CofD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142338">
        <property type="entry name" value="CofD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="575"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="8"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="575"/>
            <end position="591"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0007990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="615" mass="65264" checksum="EB0F91219AF9C216" modified="2023-09-13" version="1">MSESVSDPAAASTGSTTPSASETTTPTVTTASVMSNTLPGMPATVIGNGPGYENGEPIALPILPMFNKKLPRTNGKLHRSAPASPITPSSDLGQWDRNGQQLVPNGDGQPKKLADAAHIPSAAHSQSHEAPATPTASANGFATVVSASASVSSVSGSGVTATTTTKTAAAATTTTTTTTTSATASPTSRACSTRDGADAGILVFSGGTACNSLVHILQEMTPNVTYHIPSDKKEVIRGFLIYIQSEILKRAHKRFSFANGSIGNFFLTGARMFFGSLESAIFLFAAITGVTEPTRVLPVINTNHGIAIAALLKNGNTILGQCAISHPSSDKAMNTETKQNASKFISHDELTSPEYATLLSSSQQQEDSFSTLKLVENNIHFDKSPTRASSLQSRITRLYYINEYGQEIFPPPNPKLICSLTQMETLIYSIGSLYTSIIPCLILKDVGRCIAESRSLKNKIFMLNGTNDRETPDYTALDFIWALTSALNYSLKLSGQFWPTEHKPSKYITHLLYLDNSEVQVDTWGIEKLGIECVPCVGRKDSPSSGPIYDEEQLNKTLESILDGTWSSSIAGFTSSSSTTANSTRPSSPTPVATPLASKRDVASSLSTSTIDIGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWM0</accession>
    <name>A0A9P6SWM0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MFS general substrate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_003222</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001841">
        <property type="protein sequence ID" value="KAG0008640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWM0"/>
    <dbReference type="OrthoDB" id="410267at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17353">
        <property type="entry name" value="MFS_OFA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF317">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="34"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="108"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="135"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="167"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="193"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="276"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="309"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="340"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="364"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="401"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="444"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0008640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="536" mass="58365" checksum="138FC54958C8A155" modified="2023-09-13" version="1">MNFIRNHYSDTTLRRTPEQVEKEKTILCFPFNRWLMFPAAFIFQAICGSLYAWSVWNNPIDGEIYGLDSKNVPLKSNAPTTFYLAVGFFGLSAAINGPWLERVGPFKASLVGTTLFFIGNMLASLGIHLKNMGLVYFGYGVVGGCGLGLSYISPVSALQKWFPDRRGIAGGFAVCGFGAGSIALAKVPLPLKAAVGLTNCFITLGCCYFVVMLACCVVFRSPPPGYTVNGMDIYRNVVNSNGDVEAFKTEKSASKVENPASRMTLTDSISSSEYRLIYIMFFGNSIAGLVVLSRLSNIVTGIFDKTSDTASTIVSINGGFNLAGRMFFAAASDKLGRKNAYIVMLAAQVIILASLPTIMDAKNYPAFLAFIWILTACYGGGFGSIPAFLCDMFGPTNIGALHGIILTAWSTAGVGGGLLFTYIYNNLIKNGYTVKDTWIYSANLYWILGVAAVGFIFIMFVRTSIRDRLLPPVTGEFTRIRLFGRLIRFGTFGIKVVGKEQEEAEWGAYVGSRSSPETLQEVSYSGNKAEIEEEKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWW7</accession>
    <name>A0A9P6SWW7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Domain of unknown function at the cortex 1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_003524</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001936">
        <property type="protein sequence ID" value="KAG0008374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWW7"/>
    <dbReference type="OrthoDB" id="2119945at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013897">
        <property type="entry name" value="Duc1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34826">
        <property type="entry name" value="UPF0590 PROTEIN C409.17C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34826:SF2">
        <property type="entry name" value="UPF0590 PROTEIN C409.17C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08588">
        <property type="entry name" value="Duc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Domain of unknown function at the cortex 1" evidence="2">
        <location>
            <begin position="10"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0008374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="344" mass="39507" checksum="389BCD48DA362ED4" modified="2023-09-13" version="1">MSPSQPIRYRLRVSAGPSADPKDLKPVTVNDDANPMLIESDEFIGQVVVRLRNLDKAYGYVQGLEEDGLKYMPDSPWFTKPGGNNNLSSVQISGRFKREWKGDQIVFGNQFEKPLRLPPFSSIALKFIQFIDPGLKANIYADRPWAFSPLIATMNTVNVSGWHIDEATQRRVDHDGQDEDREHLENELPPWPSPDGEHIVEDTTILFNEHSKVEAHGKKRDDQEQAEQEERDDDDKEELVETKSGKALKESTKKLSASKRRSHFAKEVHLAKHRYRPDQVYGFDFFNPFLDFSNFTLKIPGFSVDITKYWDGQPLTYIIKSQDSSVVFMAFQYELIPINDQTIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXA9</accession>
    <name>A0A9P6SXA9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NodB homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_002878</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001732">
        <property type="protein sequence ID" value="KAG0008955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXA9"/>
    <dbReference type="OrthoDB" id="504708at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10919">
        <property type="entry name" value="CE4_CDA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052740">
        <property type="entry name" value="CE4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45985">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45985:SF3">
        <property type="entry name" value="CHITIN DEACETYLASE-LIKE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040499849" description="NodB homology domain-containing protein" evidence="1">
        <location>
            <begin position="26"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="domain" description="NodB homology" evidence="2">
        <location>
            <begin position="55"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0008955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="466" mass="50036" checksum="57F0B355D50FEFB8" modified="2023-09-13" version="1">MHFSTISLAAAISTLLIASLSGAQAETCDTTKCVFPACVCPSVNPPKGMDPKTVPQFFTLTFDDAVQAATVPVANSLMSSHRNPNGCPIKGTWFAQTLYSDYSLIQQWYAAGNEVADHTMNHYGTPSSAEITGNRMAINAYAGIPFAKMTGFRAPFLNYSKDTFDIIAQEKLQYDSSTTAVPTDAYWPYTLDYGLANDCWTGICNQTVTAPGMWEIPLHAIMDSDLATANAYNMDAQLYGSESTVSTWLKNNFNRHYTGTRQPFGIYLHPVHVGNATSLYNDFFSWAAAQPDVWFVTNQQLLQWMQNPVPASELANQTYMRCDIPAVGKEICNGLDDTKSGTIDSGLLQMCNFADGSWSTCYGCPVAQPSNSTSVPAAAVAAGQTGHRTPVPSTCAMEWWDPVAAQCLCTSSNCTFTDISLQVPKTTSTTGASPTGTNSKSSAVSSSLTSFGFVVAAVAAGLVQLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXE2</accession>
    <name>A0A9P6SXE2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Protein kinase C signaling pathway involved MAPKK protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">MKK1_1</name>
        <name evidence="11" type="ORF">BGZ80_002762</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001698">
        <property type="protein sequence ID" value="KAG0009069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXE2"/>
    <dbReference type="OrthoDB" id="10252354at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000165">
        <property type="term" value="P:MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000040">
        <property type="entry name" value="Dual specificity mitogen-activated protein kinase kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000263">
        <property type="entry name" value="MAP kinase skh1/pek1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050915">
        <property type="entry name" value="MAP_kinase_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47448">
        <property type="entry name" value="DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE DSOR1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47448:SF5">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE KINAE MKK2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 8" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="56"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0009069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="342" mass="38600" checksum="44660057377C639B" modified="2023-09-13" version="1">MDYLARNPRDPARETQYSLASGADRSPRSIRSIPETPGGTRAPDPLMNYTLRPEDMETVKKLGEGAGGTVSKVKHLPTGFVMARKHVRCDPNPDFQRLLERELKTLDRCHSPWIVTFYGAYMDGDELAICMEYCEGGSMESVYKHVADSGKTIPEKVLGKISEAVLNGLVYLHKMHHVIHRDLKPSNIVITMEGNIKLCDFGVSGDLVNSLAETFVGTSYYMAPERIQGGKYPVQSDVWSLGLTMIEIAQMKNPFPNNLAPFELLHYIVNQPVPSLPEDEPWSGDFRDFLAQCMIKDYKKRPTPEQIMEHPFIADSSIRTKDEVDMKAWIRGVWGYVDRSTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXJ4</accession>
    <name>A0A9P6SXJ4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">RTA1-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_002568</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001638">
        <property type="protein sequence ID" value="KAG0009263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXJ4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007568">
        <property type="entry name" value="RTA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465">
        <property type="entry name" value="PROTEIN RTA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465:SF1">
        <property type="entry name" value="PROTEIN RTA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04479">
        <property type="entry name" value="RTA1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040415660" description="RTA1-domain-containing protein" evidence="6">
        <location>
            <begin position="23"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="48"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="77"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="107"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="157"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="201"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="247"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="289"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0009263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="346" mass="38142" checksum="814887073DC503DE" modified="2023-09-13" version="1">MYSRGIFILLAQGLLVWGKAFAQSSSNTTTTADDDSDNDGMLAYNPNFAGNLILGILYTLLGLTFSYYCFRHKDKWAICLPIGAIASGIGFFIRLTFDMKTVQLGPFILMNCLIVISPSAFLAFNYMLYGRFITAIDPKFGNDTKPGSKMEKSQFSFIPPLIVGRTFIISDILTFFIQISAGGIQASAGDDNSSLAKIGDNLFLAGVTGQGISYLVFTFLLTVAFLRLIEDRKRNYPNQLEKGWTGLDMNTLVIVGGLYISSVFIIVRSVYRIVEFAQGYNGYLTTHEVFLFILDAAPLVLAIGVWSLNWPSILLDRIKAQTRAVNLEAGGARVDGRNGNDWMPLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXJ6</accession>
    <name>A0A9P6SXJ6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rho-GAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_001952</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001466">
        <property type="protein sequence ID" value="KAG0009901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXJ6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rho-GAP" evidence="2">
        <location>
            <begin position="125"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="458"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="853"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="935"/>
            <end position="995"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1012"/>
            <end position="1098"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="462"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="855"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="949"/>
            <end position="960"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1054"/>
            <end position="1068"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1076"/>
            <end position="1090"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0009901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1121" mass="125106" checksum="4B1164FDE48C02F7" modified="2023-09-13" version="1">MRPYSGRTPPAKSRPYSALPLRAQTDASFSVPTSAKHRSLQIPPNLLHKSSFASIVTNSTTSYTIVPNDNNTAFRISQTDLQRHVTSKEVLKQQKKTALPLFPTERTRGLATDQKVLKPLDITKIDLLPIEFSRRIIMSCIDEIRLRGLKHKYLFRNPFYSPSVEAALTLMLNPKKSHLFNVKMMRMDTVGGLLTTVISRTYPPLIPLTFLELLQSPNGYFCFELLDMLPELNRFLFVEILNICCDLVDNQLHNQISNSKLSVYPGSCCFGLDEYMPTWDTRYLLLSDVTKYSEAFYQIICSYRDERDLSAEELQQKLIKRDRMLADERLEALEREYGLEGAHDFLRREARVAQGLPPDSPKLPELPSDLKEISLYANKKEIVVADDAISVLNIQLDDGAESTKAPNLGSVKEEEEENIENIIADLRKSISVATLGSLSASLSASNYSKYSSFSNVAPSAVRRSTAPTPATRPSTRRPELERAKTLARFGSIAQNIYPVSPSDIFGTSRHAIERRELQGFLLVARTNKKRRSVASKRFKKLRLQSKTLRKSLANLAHISVFPNVPSQSRRVRNVHLAQRSSQGTHSQTHTFLLKANFATARGQRRERTRQLRKDIEVYQSRGLSAEEAMEQREADLKKKKRREKRARAAVLAKAAAAAQAEREMAAAAAAARDKANVTMEEAEILEAFDYLTDQEFEEFMSLASLTMQDVERIREKSAAAALNQVTKDIQSVDMAKTVLKAEMSQIPESSMAIGKPAATVTSDTITAEPRDPEVATFEDAYDSATDAEPVMRHKPRPSSILHMNSMDLLIKNANIIGDSNLRCYPVQTPGPTDDEPIQEVQQPQAVEVTFQIESIENEDPVIQAEEEKEEEEDEEDEEDEDVFVEASEEEEEEVFVDAMEVVVQSKEEVVQIKDEVIHVVQMKEDAVVSAVVPVENASSEPAQERTSEDSTASSVETVVSLSEPVKGLQLSPESIEDLGQSPETTKDPQPLPEPKLVTKAIPLVKQNIMRFEQSMQQKLQQKQEKTQPRPLTSAKVNISKFSAPAPAPAPAPASAPARIPSAATSPLPVRAPAPALPRTLTPAPAPVAAPSDNDSEEAAELRELLKSMTEEERQEYLRLSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXK4</accession>
    <name>A0A9P6SXK4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_002529</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001628">
        <property type="protein sequence ID" value="KAG0009301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXK4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0009301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="88" mass="9289" checksum="EE8C1BD014A78E4C" modified="2023-09-13" version="1" fragment="single">KCVEAYGLAGRHADKTVAKEVMEDLLKSMGIHLIAEGAIGTTIPGVSSVMAAISAPKVMDSVLDAVHETADQMHINAINQVRAMSNEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXU0</accession>
    <name>A0A9P6SXU0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Gpr fun34 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_001672</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001389">
        <property type="protein sequence ID" value="KAG0010206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXU0"/>
    <dbReference type="OrthoDB" id="3648309at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015123">
        <property type="term" value="F:acetate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051633">
        <property type="entry name" value="AceTr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000791">
        <property type="entry name" value="Gpr1/Fun34/SatP-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF038013">
        <property type="entry name" value="AceTr_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31123">
        <property type="entry name" value="ACCUMULATION OF DYADS PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31123:SF1">
        <property type="entry name" value="ACCUMULATION OF DYADS PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01184">
        <property type="entry name" value="Gpr1_Fun34_YaaH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="28"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="148"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="177"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0010206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="217" mass="22867" checksum="E8047EB0B6BA9044" modified="2023-09-13" version="1">MSNIQDVKENPYQVTTVPATPVTNPGPLGLSAFALTTFVLSLFNLGAGVPSGGPVQVVTGLAVFYGGITQILAGMWEFKVGNNFGATAFTSYGAFWLSYAAILIPGFGIVPAYATAPDHTLDNALGIMLVSWGIFTFMMWIATLRSTMTLSSMFFILTVTFFVLSSAHLAHLAAGNIVTRIGGALGVITALLAWYNAAASLYHPSNTYITLPTVSLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXY0</accession>
    <name>A0A9P6SXY0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Mitochondrial distribution and morphology protein 34</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10 13" type="primary">MDM34</name>
        <name evidence="13" type="ORF">BGZ80_002013</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of MMM1, MDM10, MDM12 and MDM34.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Mitochondrion outer membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <text evidence="10">The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.</text>
    </comment>
    <comment type="domain">
        <text evidence="10">Lacks alpha-helical transmembrane segments, suggesting that it resides in the membrane via beta-sheet conformations similar to those predicted for other outer membrane proteins and porin.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the MDM34 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001484">
        <property type="protein sequence ID" value="KAG0009829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXY0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032865">
        <property type="term" value="C:ERMES complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990456">
        <property type="term" value="P:mitochondrion-endoplasmic reticulum membrane tethering"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015914">
        <property type="term" value="P:phospholipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21673">
        <property type="entry name" value="SMP_Mdm34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03105">
        <property type="entry name" value="Mdm34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027536">
        <property type="entry name" value="MDM34"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058825">
        <property type="entry name" value="MDM34_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031468">
        <property type="entry name" value="SMP_LBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28185">
        <property type="entry name" value="MITOCHONDRIAL DISTRIBUTION AND MORPHOLOGY PROTEIN 34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28185:SF1">
        <property type="entry name" value="MITOCHONDRIAL DISTRIBUTION AND MORPHOLOGY PROTEIN 34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26545">
        <property type="entry name" value="Mdm34_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51847">
        <property type="entry name" value="SMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="7" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 10" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 10" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SMP-LTD" evidence="12">
        <location>
            <begin position="1"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="175"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="258"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="430"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="177"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="214"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="287"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="449"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="492"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="534"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="568"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="603"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="614"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="651"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="686"/>
            <end position="696"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0009829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="738" mass="80808" checksum="4C18D1130D9EFEE0" modified="2023-09-13" version="1">MLTNALNKGNKPAVIVDHITVKELDMGTLPPELEMLEMGELSMERFRGIFKLTYNGDAHVVLQTKVQANPMNVKKTDNPSYTRRGILAADQPLVVPMLLRISDFKLRGIIVLVVDQIKGITLVFKNDPLESVLVSSTFDSITPIQRFLQSEIEKQLRNLFQEDLPTAIHNLSQQFTKKPEDVSRQHSQDDHHRSHHHGSKPGIYDGGLGTPMVSRSPSRRSSTLGTRSESPGSRTRRDPHTEYSGDAERDLLQESLSHHANLPTQERSSRTSSRRSSRVDRYENPDIPTSSSSTQQERIYMRDNYVQSSLGIAESTHLANQFANLIHSNQTISPYAQNLEHFAFRSVPPKRPASVQYFGHNSAYRAQPLGSKGGPVSVNGSEISKDGLGNLNNSTGHLNAYTQYRNEIGGNGQSSPRISHRRLQGRVSIRRYGMQMGGGGGPRELSDHDSDEYNDVDEALSESEYVYVERQPRTSTDSETQRNHEFNGQTGSSKSKLSPSPSSASLQTIDGSSSASSSGPSPVSRPQLIRRRSPSYQNPSPSDFSNTMPGGFSSSVDPGTWAPSNKQSTREGNTRTEARPASSQYASPQEEALHRQMAAMQLNGRQLSPSSRSPFATPAATPLSPTPIGSSPFATPTATSPTSGYTLKLPSGTTTTARTFSNTQRHSQASPRPAPPEALKRDKRNSSILSSRRMSSVGIGLGVLSKEGDKKGTSLESRPSRPFKPITAHSGWSEPDSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SY50</accession>
    <name>A0A9P6SY50_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_000850</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001188">
        <property type="protein sequence ID" value="KAG0011204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SY50"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="68"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="76"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0011204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="92" mass="10032" checksum="4D703C5E405976C4" modified="2023-09-13" version="1">MAVASRETTHELLSGLMYHNGDGAPRDPTKAAEWYLKAANQGDADAEFILGILHRNGYGILTEMSGNNGAIREQPRNGSQEQFSHQQSNSAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYL8</accession>
    <name>A0A9P6SYL8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Magnesium transporter NIPA-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_000205</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001035">
        <property type="protein sequence ID" value="KAG0012102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYL8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008521">
        <property type="entry name" value="Mg_trans_NIPA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570:SF9">
        <property type="entry name" value="MAGNESIUM TRANSPORTER NIPA8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05653">
        <property type="entry name" value="Mg_trans_NIPA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="180"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="273"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="301"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="326"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="367"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="657"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="699"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="733"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="765"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="439"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="835"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="473"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="509"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="598"/>
            <end position="610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0012102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="855" mass="92686" checksum="238CC8157CF048BE" modified="2023-09-13" version="1">MPSTCTTDFDCLQTTRPADWPREHDTVQSGNYACVFGSNAGSTNSTGQSTGTCQFVVAAGEQCGVPSDCAAFAFYSQRNLSVPSDLCSPQYCTIESTCGSPWQDSNAPSNHSFGESGITSCCGGQPIDAICSLIGSNVETCEYHSTCSFDVDNGVDGLSPDQMRQQGLGVCQPIDQRKNVWIGVVITLISSTVLNLGLNGQKYALRKHDERRVLKELEMEEEHERWRQELGWTEEQVQQEADRLYEEKENRRGSLYRRLKPYMFWRNIFVSKLWALGLIVFIIGNLGGFVALRFAPQSLTAPLGSISLISNVIIAPIINKEVLGKWDLAGIFFIVAGSVIVVVFSGIVAQDYKLCVLINLFHKTSTIVYLSFIGVCIISTFFFIQFVEKNVENEADVAIGVSAERELLREGRLYRMNSNMSNLSLKDRQESLHGALAGPLAAAPRSSEGGEGSKTTEFEKLPARPFAQRPEVSVNSTISHQTITSDTSDTAVGASSAVGTEHPHDNRRASFGSGRSSSSSSSGASVPSLNAKASPATTIPGKSGAVNGKNGPRLKFGEPLKSPGVSAPSTKPAVNAVVGSTAEVEDGTDSWPSHPGVGSSQPVVSINSSHRSIRKRRNRDHNMNEDGTPMTFWERVKRIEFIPSLPEDKLIRRNSPLLRFCLPLSYAALGGMMASYTVLFAKSLINLLVTSIFDGDNQFTSALAWVILVVTVVTAVSQVYWINMGLKKYDALLQVPVFFTIWVLLDIVGGGIYYGEFSGFTAQKYVLFCLGVLIVFFGVALLAKRLAVLAKEDVGESQVESVVPSRRDSVMKEFSGGEGVVGSKQPLAVQETVGSKITPASPPSTSVVIVEDRTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYZ1</accession>
    <name>A0A9P6SYZ1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_011667</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000968">
        <property type="protein sequence ID" value="KAG0012546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYZ1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056251">
        <property type="entry name" value="Arm_rpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23948">
        <property type="entry name" value="ARM_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05729">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arm-like repeat" evidence="2">
        <location>
            <begin position="159"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="domain" description="NACHT" evidence="1">
        <location>
            <begin position="628"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="717"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0012546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="717" mass="80497" checksum="02872B1487C29F6E" modified="2023-09-13" version="1" fragment="single">MHGLFSSLTNTLSAEETLGLVNVYLTSARNVKEKAIALALCDNAEASLLPIKKLLKKAQTPLSTIDQALRDGVGKAYFDCGRLLEKLGQNERSQANYKAAKKLGHDQDVERLAISSQHERLKDTLQLAYCLSLLQPSSSSDDTTSMFDDTFTQKERQWIQITAADENELARLNTLATEMTRNFIKDELKDAAIVSEIVSFASVLNQQNFKLLLEKFLQGIGNSLLEKRYLLEGLAQMMQRATRGYLEKDDLVKILQLLNTRLNDIHLESNEPIYQLTRTVSHVLDAMVDSDVKHLKRELLHEPLSAHLKSSQESSDPYLVYQTAYAFQALQYVPDDETFLQAALRRTGKVAKGVSGIVSAMKSLDLCRLFESLQNIQQGLTGTLEFVGLMKDAYTQVASLAESGKAFLACLQEGFSFDRKSAWYPALRAADTLLQNGQLVEFKELACQVACRRDPAFQWGLCERLGQLATNADPYTRQGAVAFLGELYKNDVAWGQHVSIKQWILKILIHLSDSSVGTTTPDPDSAAQTLLQALANEGDESKRDLYKRCLQESEKCGSPYPMKAILPLPGSPSLLNRVQNKPDVEADLRRMKQQRLKERAKPSLQAPEEALLDLTQKVDEFLHSDKKVLLLLGDSGSGKSTFGRELECKWWRAYTKKTDRIPLHINLPAIDKPEQDMIAKQLRKGGFTEPQIVELKEHREFILICDGYDESQQTHNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-10-08" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZ45</accession>
    <name>A0A9P6SZ45_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_000288</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001055">
        <property type="protein sequence ID" value="KAG0011983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056251">
        <property type="entry name" value="Arm_rpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12697:SF5">
        <property type="entry name" value="DEOXYHYPUSINE HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12697">
        <property type="entry name" value="PBS LYASE HEAT-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23948">
        <property type="entry name" value="ARM_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13646">
        <property type="entry name" value="HEAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05729">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50837">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NACHT" evidence="1">
        <location>
            <begin position="676"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1645"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0011983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1645" mass="183780" checksum="62C946ACF1BB1168" modified="2023-09-13" version="1" fragment="single">MESYLLVDPAPPAFPTPPVYSVDPPDKVANNGMDYIQKGDRCCDIGDFKGAAKCYEQAIRYYPELAQERLKRLPLDVGLFGELTASWDARTLRVKKYIAELSNKSPREFTLTGPYFPKRALSLQEALEFEKSPVPQIFGNADCAVGEPLTTISLVTSYVKAESPSKVELRNQIKPVIMQFDKNFISLDTVQELVILATIPDREIFIGIANQMLKVLRDSPILSCEVLQGLAVILNACPEQIDLSNDHGAFQDILKPIADRLNVVRQDKNGNQLIPLLRAISALFDAMICRKVVGVDRDSTYIPLRNLLRGFSKHSDPTVSYLAQYASQGLEFIGDDEPMQMTIFRYGKLAFALANDVKDIAVNMDISSFASAYDNLTQLCDFPKKYVWYQGLIYLNCAMGLKDWSQFEAFVTNSKLKSDERFLQGVCLYLERIVATQVNEDVRNGATRFLYALMSKSSRPVQKVAQSALQRLGIKTETGTFANGFLKLFASRSATCVVPQVSQEDIPPIWDPLWYSNPSNVLLRIVQAKMQRDKNISALLKQVEVLQLDVKASNADLKADMDMKLGEILSDVASIKDSNTTTPSTLEEVHAALHNHYRGNFFVQRVSGDKKSLDSCFINLAVVAAQDQKQKDKEELKASVMISSQERKKADPLVSIPIEELFDKRKLRDGRVDAPKKILIHGRAGVGKTTLCKKLIHLYQQGALWRDRFDAVLWLPLRQLRTLKPRNLEDLLYQSYFSSHLNKEKEKLALSVINLIRDGKVLFALDGLDEIVKDTQSQDGLIMEEFLKNLLRQEYVVITTRPSGVDNSILPKLDLELEAVGFSSKNVEDYISMAFESDNKTAESVRDFIRRTTLVQDLIEFDESTIRRTVDDLDGYREEAGLEALPFELFENLKQMSFLHTSDAGLDSGKDNSRRSWYFLHLTFQEYFAAAWLVRHLQTKRTNPTKPSVVSMTPRQTTEFVQRYKYDPRYEIVWRMVAGLLEGSALESFFDLLQRPPRDLIGARHRLLLAGCYMESQPSLSGDSVKWIEKELRQWLQFKMKLKGQGVDERNWRGAITDEVSTRSLEKDMDEQVRPTKAPSLFERPVPRRRTRVSPLCCHLTSYACIGSICHPVVPGVLKPDSSAVWSEESISALIKRLQNEDLCVRISAAERLSSLHYPPKLPESGITALISALQDDSSDFRKLVAKALGGQSSLPEYAITALVTLLKDEVSDVRVSAVKALGCQSPLPEYAIAALASSLKDDNSEVRRSAVNVLGQNSPLPEYAITGLICSFQDEDEGVRSLAVEVISNQSILSESAITALVATLQSQYPDSRRSTVKMLGQQPSLQEYVIIAVIGSFQDEDEKVRSLAAEVIAAQFTLSEPAIIALVAALQARYPDSRRSTVKILGQQPSLQEHVIMAIIGSFQDEDEEVRRLAAEVTGGQSTLSESAITALVAALQSQYPDSRRSTVKILGRQSSLQEYVITALIDSFQDEDSEVRRLAAEMIGKQSIISESTIVALVALVAALQSEYSDSRGFVVGILVQQSPLQEYAILSLTASLQDKRVDVRRSVIQVLQCQPTLSESTVVALASSSQDEDYQVRESVVDVFSRQSLLPVPAVAALEIALQDEIQYIRELSAYALGRQPTLPDSAVAALVTNIQDKNRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZX7</accession>
    <name>A0A9P6SZX7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">NADH-cytochrome b5 reductase</fullName>
            <ecNumber evidence="12">1.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">MCR1</name>
        <name evidence="14" type="ORF">BGZ80_010557</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10 12">
            <text>2 Fe(III)-[cytochrome b5] + NADH = 2 Fe(II)-[cytochrome b5] + NAD(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46680"/>
            <dbReference type="Rhea" id="RHEA-COMP:10438"/>
            <dbReference type="Rhea" id="RHEA-COMP:10439"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.6.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11 12">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion outer membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.6.2.2" evidence="12"/>
    <dbReference type="EMBL" id="JAAAID010000747">
        <property type="protein sequence ID" value="KAG0014250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZX7"/>
    <dbReference type="OrthoDB" id="432685at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090524">
        <property type="term" value="F:cytochrome-b5 reductase activity, acting on NADH"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06183">
        <property type="entry name" value="cyt_b5_reduct_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000032">
        <property type="entry name" value="NADH-cytochrome b5 reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.80:FF:000009">
        <property type="entry name" value="NADH-cytochrome b5 reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001834">
        <property type="entry name" value="CBR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370:SF171">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00410">
        <property type="entry name" value="PHEHYDRXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11 12" id="KW-0274">FAD</keyword>
    <keyword evidence="4 11 12" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="8 12" id="KW-0520">NAD</keyword>
    <keyword evidence="7 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="13">
        <location>
            <begin position="81"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR601834-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU361226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0014250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="330" mass="35467" checksum="5B6906137C885800" modified="2023-09-13" version="1">MFRLINPLKATARSIPRHAYSTSSKSSGGSGKLVTVGLPLGIATAAAYAYYSDRLGGAIASNAEPAVVAKKVPITSALDPNAFVDFKLKKVEKLTPNTSRFTFELEENQKLGMDVTSCVITKFAKEDGKAVIRPYTPTSDADQTGSFDFVIKHYENGPMSTHIHSLKPGETLSVKGPISKYPLKANQHESVSLIAGGSGITPMIQIISGLLKDKTDKTKINLIFANVTPEDIILKDEIDAYAKAHPDRFKVTYVVDKPVDGWKGPTGYVTAELIKKYNPEIGTGNTKVFVCGPPLMVKSVSGPKGPNFTQGDVGGALKELGLTNEDVFKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T062</accession>
    <name>A0A9P6T062_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">G-patch domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_010700</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TFP11/STIP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000774">
        <property type="protein sequence ID" value="KAG0014031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T062"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071008">
        <property type="term" value="C:U2-type post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000390">
        <property type="term" value="P:spliceosomal complex disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022783">
        <property type="entry name" value="GCFC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022159">
        <property type="entry name" value="STIP/TFIP11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045211">
        <property type="entry name" value="TFP11/STIP/Ntr1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23329:SF1">
        <property type="entry name" value="TUFTELIN-INTERACTING PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23329">
        <property type="entry name" value="TUFTELIN-INTERACTING PROTEIN 11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01585">
        <property type="entry name" value="G-patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07842">
        <property type="entry name" value="GCFC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12457">
        <property type="entry name" value="TIP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00443">
        <property type="entry name" value="G_patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="G-patch" evidence="8">
        <location>
            <begin position="271"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="320"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="60"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="72"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="99"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="117"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="173"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="197"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="233"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="320"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="351"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0014031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="993" mass="110451" checksum="E552243AD2A42CF6" modified="2023-09-13" version="1">MHRSRRKRTKEEAIYGSFYDWGSDEEGASSRPSGSRSGGRRREGFEFVAASSSSSQQKTRTSDTRDKTPADSSDENMEEDDEQSRASGSDDGSKSVDDGGMDLDSENDNSDEDEDEREARLEREAAFKAQRERDQEEVDEYEDRVQRPQMGKKPGIGLGSGAPPQGQESAADSPTSSTSTPSNNKAMAATIKAGLGLSTNSGPKSQKNKGNTHGSLSFFKNRANFGEAGSNPSTPPSHPTTPPSAPSPKPDMPAIAPVKVGRDYGAFSAKGSGFGLKMLERMGWKMGYGLGVGGTGIVEPIQTKLRPVKMGIGFKGFKEKTEQARAEEKRRGVVSSDEDETPGKSKSKSGTKKEDEPKADGWKKSSSRGSRKGPKVEYKTAEEIQREIESGDMPMTQAQPQKILDMTGKTVRELSSASQISSSMPFQHERFPELRHNLQLMADISTTDLEQLARAQKADHVRQKVLEAEGERMQKLASQDEINLERLTRVLAITDQCSQIANEIQEATSDTTGAVIIEIKEDYIVSAFKEPFDLFSGLYYEEYKLYELDQAIIASVQDSFKKLLKDWAVLKNPTLGSGLFKQWQKLIRTSKVVYTNDRETGGFYGSKPSLPEQMTAYESLLNQYWLPKVRSAINNDWDPRDCDPVIELLEAWAPPLLPAFIHDNIITQLIMPKLQKEVEQWSPRDSLMLHTWIHPWLPVLGQSRLDQELFGTIRRKLARGFDAWNVLDPSALRVLEPWRGVFEDTDMELLLLKSVLPKLVEGLQMFEINPRNQKIEILQAVLPWYHFFPSTTFSSLLVNEFFPKWHQVLYLWLTHPTTTDLDQVSQWYQWWKSLFPPELVQETGVAVGFRQGLDMINQFMAGLKIMAPADLAQAQAQTLGKNGGAANGGSLDPLGRLQTKKHLVPSISFKDLVLDYATQNSLLFVVTKQTHERSGRPLYRLGGNSTGTAGGILVHMTDEVAFVKSEETGVWMPTGLEELMILAGAGKNGGSRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0B5</accession>
    <name>A0A9P6T0B5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">EamA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_009696</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000603">
        <property type="protein sequence ID" value="KAG0015705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0B5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23051:SF0">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER F5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23051">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35, MEMBER F5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="124"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="193"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="224"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="263"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="290"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="318"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="6">
        <location>
            <begin position="193"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0015705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="374" mass="41416" checksum="C07D98DCF020B2B2" modified="2023-09-13" version="1">MGLFQFLDEYKHYNKPFFVTYVNTASFSLYLLGPFFKYWLRKFRGYKFNPPPTARTIRRTRSSYGSISLSGSLDAQLLTESILEQGSEVVNPDDAPLNYRQIARLSLEFCILWFAANWSTNASLAYTTVASSTILASMSGFFTLAIGAFMKTESFSTIKLIAVCGSVLGVALVSESDRRNSNIEPSSPPAPIFGDFLALMSALFYGCYTVLLKVKIQNENRVNMSLFFGFVGMFNLLLLWPIFGVLHWTGVEPFELPHDPRVIGMILVNAFVGTFVSDYLWLLSMLLTTPLVVTLGLSLTIPLALLGDVIGYGRVLGLGYWVGAGLVLAGFFGVNGAALTEISEEEKQEEELTQSIEVTNMTMTTEEGEPLLAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0E6</accession>
    <name>A0A9P6T0E6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">C-CAP/cofactor C-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_010367</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="6">Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TBCC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000713">
        <property type="protein sequence ID" value="KAG0014570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0E6"/>
    <dbReference type="OrthoDB" id="194775at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015631">
        <property type="term" value="F:tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007023">
        <property type="term" value="P:post-chaperonin tubulin folding pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007021">
        <property type="term" value="P:tubulin complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1250">
        <property type="entry name" value="Tubulin Binding Cofactor C, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017901">
        <property type="entry name" value="C-CAP_CF_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016098">
        <property type="entry name" value="CAP/MinC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006599">
        <property type="entry name" value="CARP_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027684">
        <property type="entry name" value="TBCC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031925">
        <property type="entry name" value="TBCC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038397">
        <property type="entry name" value="TBCC_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012945">
        <property type="entry name" value="Tubulin-bd_cofactor_C_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15139">
        <property type="entry name" value="TUBULIN FOLDING COFACTOR C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15139:SF0">
        <property type="entry name" value="TUBULIN-SPECIFIC CHAPERONE C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07986">
        <property type="entry name" value="TBCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16752">
        <property type="entry name" value="TBCC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00673">
        <property type="entry name" value="CARP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51329">
        <property type="entry name" value="C_CAP_COFACTOR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0007">Acetylation</keyword>
    <keyword evidence="5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C-CAP/cofactor C-like" evidence="8">
        <location>
            <begin position="109"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="93"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="100"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00026055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0014570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="312" mass="34802" checksum="8C84C703AF254643" modified="2023-09-13" version="1">MAEASKDFRATFDAEKRDIERELAGLDKVPKTDLQPKIDSLVQQIHALEKTVTEKIAILPPYDARMCVEAIKSMSEQLSLLRTKLVPKPKFSFKSRKAGSATSSSTSSPASTPKPASSPKPTTTTSAIDQSLFMKFEDRTGEHIFIGSLPRPQDDGVAKDVALTNLTDCTINLVHDIPLGAIHIKNLKRCTLVIPPVSGSILLHDCEGCTLIGACHQSRMHTSRNMDIYLHVTSEPIIEDCTDMRFAPYGQILPPEQLDRLFEVAQLNASKNYYDKVKDFNWLRQQQSPNWRLLEAGEIKELAQEVLAKDRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T178</accession>
    <name>A0A9P6T178_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF1748-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_008190</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000437">
        <property type="protein sequence ID" value="KAG0017536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T178"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013726">
        <property type="entry name" value="Mitofissin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28075">
        <property type="entry name" value="CHROMOSOME 16, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28075:SF1">
        <property type="entry name" value="DUF1748-DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08520">
        <property type="entry name" value="Mitofissin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0017536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="72" mass="8000" checksum="63DFEBD6D7C6FA61" modified="2023-09-13" version="1">MISKIVHYAADAVLVSAVLAGIKRSTGLSVATNKIESDDVRVYVDKYLTIGEWVVDQGTAFMSTSQYFERKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1L4</accession>
    <name>A0A9P6T1L4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ras guanine nucleotide exchange factor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_007692</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000399">
        <property type="protein sequence ID" value="KAG0017967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1L4"/>
    <dbReference type="OrthoDB" id="546434at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007265">
        <property type="term" value="P:Ras protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00155">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06224">
        <property type="entry name" value="REM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.840.10">
        <property type="entry name" value="Ras guanine-nucleotide exchange factors catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.870.10">
        <property type="entry name" value="Son of sevenless (SoS) protein Chain: S domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008937">
        <property type="entry name" value="Ras-like_GEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000651">
        <property type="entry name" value="Ras-like_Gua-exchang_fac_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023578">
        <property type="entry name" value="Ras_GEF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001895">
        <property type="entry name" value="RASGEF_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036964">
        <property type="entry name" value="RASGEF_cat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113">
        <property type="entry name" value="GUANINE NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113:SF348">
        <property type="entry name" value="GUANYL-NUCLEOTIDE EXCHANGE FACTOR RASGEF, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G04700)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00617">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00618">
        <property type="entry name" value="RasGEF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00147">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48366">
        <property type="entry name" value="Ras GEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50009">
        <property type="entry name" value="RASGEF_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50212">
        <property type="entry name" value="RASGEF_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-terminal Ras-GEF" evidence="5">
        <location>
            <begin position="49"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-GEF" evidence="4">
        <location>
            <begin position="451"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="193"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="267"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="7"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="31"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="196"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="267"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0017967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="694" mass="78367" checksum="9DA75785AAE339D2" modified="2023-09-13" version="1">MSLPGIKSSNIGNLNGNRSLLPPSPSPKSSTFNPDSSNQTGSRRSSKDSVDSVPGVTLDELVDRLTVPDADHFEYFVRMKIFLMIYRKFLRPRELLEMLIQRFEELGDCAENEDEKVVENKNNTRDSICMCLRYWLRNYPNDLIHRQTRQRLASFLRERVALFPRLNELYAELVPLSSIQYFQAWRWPQGDHSDSRSSSVSGPSLSSLSSDDDNDSGFYDATGAMVSEQDMDEDREWGLFDEEDILPEAKKCLSLDSLAPFPQAIGASINSSNNSSRASSRLISQLPRDRRSSTGSLAHTSPCAMEAFVASRRGSGSSVNSNNQSVHHTSFVSPLGFTEGDLTLFQHQHQHQQQLQHPQPQLHQPLFQPMISIPFIGKRSSSQAYRQKQQLNNGMSPAPSPLLQGTIHSNTSLIFKETIEDGPVHPLQGRASPLPPPIDYLSVNTPFIEIKDGAIAAQLTCVEFGLFRKLKPRDMLRQVWKTSKGSAAFQACIAHFNFISSWVGTMILSPSKAKNRAKMMEKFINIAKILRDMGNFNTTMAIIGAMNTSSIHRLVQTREHLQGKEAWTTFKELEHLMSSERSFFEYRQALKVQKLPCIPYLGVHLGDLLSISEGNRDLRQDGTIHWQKFCLLTDVISMVMQFQSESYVIQPDPFISRVITDTHVLDDEELYTKSVGTEPGKLHHSRSLSKFNFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1U9</accession>
    <name>A0A9P6T1U9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Arm-like repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_006381</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000315">
        <property type="protein sequence ID" value="KAG0019044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035097">
        <property type="term" value="C:histone methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000228">
        <property type="entry name" value="COMPASS-like H3K4 histone methylase component WDR5A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.80">
        <property type="entry name" value="E3 ubiquitin-protein ligase SopA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056251">
        <property type="entry name" value="Arm_rpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847:SF637">
        <property type="entry name" value="WD REPEAT DOMAIN 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23948">
        <property type="entry name" value="ARM_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="16"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="16"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141571">
        <property type="entry name" value="Pentapeptide repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="14"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Arm-like repeat" evidence="6">
        <location>
            <begin position="238"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1252"/>
            <end position="1293"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1294"/>
            <end position="1335"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1336"/>
            <end position="1377"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1378"/>
            <end position="1419"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1420"/>
            <end position="1461"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1462"/>
            <end position="1503"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1504"/>
            <end position="1545"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1546"/>
            <end position="1587"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1588"/>
            <end position="1629"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1630"/>
            <end position="1671"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1672"/>
            <end position="1713"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1714"/>
            <end position="1755"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1756"/>
            <end position="1797"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1798"/>
            <end position="1839"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1840"/>
            <end position="1875"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1927"/>
            <end position="1957"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="2032"/>
            <end position="2093"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="2167"/>
            <end position="2215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1933"/>
            <end position="1953"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="2040"/>
            <end position="2066"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="2068"/>
            <end position="2077"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF23948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0019044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="2253" mass="250391" checksum="171E7C91E6046FB2" modified="2023-09-13" version="1">MVRNPFSSPTSGLSLNDALEIANRHLENARKENDPEKALRLIRNAKSVIKDAERIFTAARVGNQNQDDGIANAYFEHGRVLEELGYHNKAQKSRSKAEKWGYIHTSSQQTGSSRLGNIGSPLRLSLCPPAALSAIPSIAAAIYQGIPESEVELLTRQNHSQDATSKEIEICMLDASKDSAQIPRAIFGQGVAPPVTKYALPEADGRITSASQLAYCLSLLDPLLISEDELDENERDWLQAKLNDPDEQQRLRAMATDVIRAFARDELKKPNVVAEVVSLTAVLDQDDFRRLLQLFVDGIAQSVLLEVHLLDGLAQLIQNASPGFIDADDLIKVLELLGTRLRDIHSQSAQHSYRLALVVSRVLDSMVDNRVEGISHEHLHEPLSEYLQDLQHSSNTSLVYQAAYAWQALQYIPDDEPVLETLLRRTGKLTLGVSGVVSAVKALDLDRFILGLQSIQGGMAGAGNAIEAVKETYSDARALIGSGQRLLESLKESTNFSCKRVWYPALRGLDILVQGGLFAEFEKLVREAPCQYDPAFQCGVCQRLGEIAANTVWNADIRGGAVIFLGDLYKDDVKWGREVSIRQLILSILNQLTDPSKGVIADQAQTLLQELERDGNSEERALHQSCVQDYAGELPLMVGLPQQGSLLLDRVQDKPDIETPLRQLKHIRLKERGEDVYISPRAKAGQTAMGDFDLTSIVQEFLASERKVFLLLGDSGAGKSTFNRALEISLWDKYDKVGGRIPLFIHLPAIDKPELDLIAKQLRILDFTDNQIRELKMHHEFVVICDGYDESQQTRNLYTSNQLNQPGGWRAQMVISCRTEYNGVDYRDCFRPASRNGGGNLKLFQEAVITPFNADQIQDYVDQYVLMRKSSWESKDYQKAFKQIPNLQDLVKNPFLLKLALEVLPLLLDTSSEFTAARITRVGLYDRFVEQWIERGKVRLEEIELSSRDKDDFKILLSSGFKDLSIILLKELATAMYDNQDGNPLVSYSDYRDRKTWKEGFFNDRDGRHLLREAIPLIRNGDQFKFIHKSVLEYGITLSIFDPNEHNEDMEPTSAKTRRGSAASTLSFEAPAIAEEAMIPIEQSLLDSPLGRRTFVRDPSILLFLVERVQEQPVFKDQLLALVERSKTDKSARIAAANAITILVKAGIQFNGADLRRIKIPGADLSYGVFDSAQFDGADLRKVNLRSIWLRNANLDGALMTGAQFCELPFIQEDSSVNCCAFSPDGNIYAVGLAGGDINLYETLGWRRIQPMKGHGGHINDLAFSAVGDQIASGGNDNTVRLWNVESGDCIHTLEGHSDSITSVVYSPNGGRVASGSSDKTIRLWDIESFTCIQTFQGHEEGIIRLEYSRKGDQIASACWDSTVRLWDVKSGSCVCILQGHTNSVHSAVYSPKGDQIASGSWDTTVRLWDVESGNCIHTLRGHSSMINCVTYSQGGDQVASGSWDRTVRLWDTETGKCVHTLEGHDSDIICLAYSPKGDQVASGGHDGTVRLWDVDTGNCIHNLQGHISRVTCFAYSPKGDRIASGSWDDTIRLWDVDSGNYVHKVQGHSDTITCVAYAPNRSQIASGSWDETVRLWDIDSGICVHTLRGHGSMITSIAYSPTGSQVATGSGAQTVLLWDVDTGNCLHTLLGHSSRINSIAYSPEGSQIASGSDDASLRLWDASLGTCIHNLEGHHSEITKIAYSPKGDLIISGSEDTTVRLWDVNTGGCIHTLQGHSMRVVEVMFSPNGDLAASGSFDHTVRLWDVKTGNCVHTLQDHTEYITSVVFSPKGNWLASGSEDNTLRLWDVESGLCIHTLEGHTHFVASIVFSPEGDQVVTGSRDDSVKLWDIDGGQCLATITGFKGSINHLVWEKTLHGQYLVTGSEDRSVRRWQIIKEGDEHKMQLVWSTSHKVLTVNNASFEEVQGLSQLDWLLLAQLKASNQNSRDSATLQSQSPLIQQQQHQQRQTTATSNRKSCSVAIKTISNTIKQRGSKATAGEGDTTKGSLQKRISDVCPVFNRLAEIFETDFDPNPLIGWDSITAVDNFNHDQEAEISSSSLDEDEDEVEEDDEVEECDENSEVDSSDDNTGFRNNTPTAGRMMNKGGGPASKRRKIDPELQKLERLERAVASLAKPRQQALNQLEAIRNDLKNREAVLLAREQELTKTLHEREIAHAAVLRQQSLDHEKMLARRIEEHERRVIELKEEKEEFKAQKEESKAEKEELKKQREALAKRWGAFFRAYNPRDDLRVQEEAVSAGLDGSLIQDRNKSFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T250</accession>
    <name>A0A9P6T250_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_006383</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000315">
        <property type="protein sequence ID" value="KAG0019046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T250"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0019046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="291" mass="32600" checksum="87043EFB3045C6B4" modified="2023-09-13" version="1">MSGGACAFFRHNNPGLLRDAESACIMENIEKHPCTSILKEYADVILENGVEYLQRRLAVDLGLLNAEILEGETVSDAADIRDRTLKVLLMLGEKAMLASKIIRQMQSSEFGDPSDMGRRADCLFMFDDIEISNIEFKKPSTSEAEIGLQNRKNVRLGRCLQQGFVEFGVAEPSVVMADVAGYVAVFYQVKQMGDLHVAGKITPHLVQLPSTDGALWEFLTSPSLAIIWNYLDHLEKQGPKLRMIKRKHEVSISKQKMEQGLSRAKSETTVIRKFEDNVVFSPPRKKIINAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T259</accession>
    <name>A0A9P6T259_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007178</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000363">
        <property type="protein sequence ID" value="KAG0018430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T259"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="55"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0018430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="316" mass="35771" checksum="DC00F24F6EDC859C" modified="2023-09-13" version="1">MGGDHAAEGFSIEFMYEHPQTAYEDFASDITNSKLKENSKRDNLPDPFAEEDITPSSSKWIPSSRSIGKRTAAPMPQTSNKKSSEVTMAGDEYVGVEEDPDSDETVDQHDDTIDEISKSRGAVDEGKTFGDDNDINNDPDDDQVDDQYEEDGEGEVTVEGLIQEIQALKEESESGFYPLIRALYHAARGEQFKKPQHKPQLSVCQSFLYDYVWNRLDTFLELSTVEQKDVLVAIIGIVDLDGHKDFPQHADLLSECRAAIELQYPKIRDHLQTYRRFVDDDDGLKEARLGELMKQLKEDMSRFEDGSDEMVVIEIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2A8</accession>
    <name>A0A9P6T2A8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005411</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000267">
        <property type="protein sequence ID" value="KAG0019683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2A8"/>
    <dbReference type="OrthoDB" id="2444470at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0019683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="207" mass="21869" checksum="4A75AB8CC96D8CF9" modified="2023-09-13" version="1">MTLRGGGGPAEYRNPPTKAPLYPLPAIVATVSAWLLQYHSGLQQPQSERRGIATDFYMGTQKFSPASSVASSRTAALDVTPTPAETDVSGGSITGITIGLLAVSALAGFSAFWWRKVRHNNSLFDGCPSHDVDGPIRTVITEKIESVVRTVPQAGVPYTADSIPVQTNYCAVTPVITTASNPIHSHAAIAVNLVNTVQHPPVSNNSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2L0</accession>
    <name>A0A9P6T2L0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">YEATS domain-containing protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">YEATS2</name>
        <name evidence="5" type="ORF">BGZ80_004456</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000227">
        <property type="protein sequence ID" value="KAG0020294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2L0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16907">
        <property type="entry name" value="YEATS_YEATS2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1970">
        <property type="entry name" value="YEATS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038704">
        <property type="entry name" value="YEAST_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005033">
        <property type="entry name" value="YEATS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055129">
        <property type="entry name" value="YEATS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23195">
        <property type="entry name" value="YEATS DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03366">
        <property type="entry name" value="YEATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51037">
        <property type="entry name" value="YEATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YEATS" evidence="4">
        <location>
            <begin position="516"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="111"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="252"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="651"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1015"/>
            <end position="1034"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="15"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="111"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="129"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="296"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0020294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1077" mass="117116" checksum="E522712F3CD92CD2" modified="2023-09-13" version="1">MSLPQENDSDGIANATMTPATATSVPTLEMESSTAPDLSNKLTNPLVGQSSSSTPDSNVDTTRQKIVDIIEHQFDLEILLRHAEGATIAQELAKAERMLEDLRHAILSERQGSPYGNSTVSRTIGGPDSHQSNRQSSRRTTAYYGRDVRQPEALYAVRADGQFVKYGPKRISNLFCSPGSRARVNRVLGCPKCDRYDFGSIQGLINHMRLSHKLVFKNTEEGVRYCGIVVPSSEVPLDHSCRTKIVFSSLGASDASHGQQDFPKPTIKTYDEDVDLESDDGRARNGSRRPPQLRKNSGASNNSSSNTGSESESDTSDVISAGESGTGAGMRRRSSLALSVARPHKGTPGSKVNGESDSDGTDDNRNSGNEAIRPPHGGKGPMRKYGAMSQGPSAINANTGRPGMTSRMTIGNYTVPDSAMSSAASSRATSPSLHPLMNETDISEPPTPIARFPPPSLPIPSQNTLANPLAVSPAVPPFNTLTGGVTNQHPQQLQPTIISFGATAIQGGVPAPLDTVGSRFYVKRRVVVGNVSKYLPEDKRDPRLKEFPYKWMIYVDGTPKPEEITAYVSKVEFHLHESYKPNHIITVSEPPFHLSRYAWGETQIKVRLFFHDARNKPVEVYHRLALDPTHCGRQVHGRERYVDLELDRNTTFKPSTPFQSRPKGSSSKSHSRNNLILNSAAEVAMADGAEEDEQELQKTLSRPAVLAVGAHGTGAESSRTGAQNGSRAAIDTVRAASIDDGPVMKNKVKETNLLFCKACGSFWKQHRDGALGVAGTASEPILLNEDNGLQIPNCPHHPNFYAVKSLEKDNQMLLSLLVGRTKNKFALDMLEKCGIVDQHGQPISNHDRALMEMHQQSDSAMDLDIGDSELLPSPSNPASLLTFEQQIKAQQLSEAFQNIEVYKCRRTEIDWVLSVMDELKLKTLFLDGGVGGGSGGSRSGLRERDQEQERLLNTPGLTKVPDSMSQRAVVGGLLVQATKAFLNSILSKATSIHRHETEAEKGPESIMMELDALNDSEGEGDKHGEGAGSGTKKTKVSDKLLAPYHIYQALQSNPEELDFLTSQYEDMEGIGEMMGGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2M3</accession>
    <name>A0A9P6T2M3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Amidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_005810</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the amidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000286">
        <property type="protein sequence ID" value="KAG0019445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2M3"/>
    <dbReference type="OrthoDB" id="566138at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000120">
        <property type="entry name" value="Amidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020556">
        <property type="entry name" value="Amidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895:SF67">
        <property type="entry name" value="AMIDASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895">
        <property type="entry name" value="TRANSAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00571">
        <property type="entry name" value="AMIDASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="3">
        <location>
            <begin position="139"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="245"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="245"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0019445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="610" mass="66459" checksum="71E9AA502CDA70DC" modified="2023-09-13" version="1">MSSYNLKNPNTPIASGRTLVFLTNTLETLGSSTGLTSYLCEDAGLHSLRTIKYSEPPTAMPVFAPTQDMISAATANGSSTLNARGYLEIIQKQADAEATRGDRPSSAEHKFLTCRDFYVSYKSGRKTPTEVAEQLIEAIKTSDEISPPLGAVWNWDKEAILKQARASTLRYKEGNPLSIVDGVPVVIKDEIDVEGFETGVGTKYINKGNPAKEDAHLVALLRAHGAIIVGKSTMHEIGLGVTNFNPSTTTPRNPYQPQHSTGGSSGGSGAAVGSGLCPIAIGCDGGGSVRIPSSYCGIYGLKPTHGRISSRGEYPLAPTVAVSGPMCATMEDLAIVYAIIAGQDEKDSYSCIQPSVALPAPIGSRSGGQLQGLRIGIYRTWFEDVIHPEISQVCYKMLESLCKEHGAVLVDIEIPELFENSKAHNMTIVGEMLSVVSMDHYKLHHQTRLELTMMSSLKMEDFFRAQQQRTRSIRFLETLFGHKTHDEYHQARYPCLGGKDGIVDVIVTPSTGNLPPKINPGALSHGESNYLNTVKTMQYMMLANHTGIPGITAVAGYSKDEYANQTGFPIGIQFMGQWWDEKRLIHIANVCEQVLEERQKPKIWVGDYKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2Y4</accession>
    <name>A0A9P6T2Y4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="14">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">BGZ80_003672</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="14"/>
    <dbReference type="EMBL" id="JAAAID010000199">
        <property type="protein sequence ID" value="KAG0020739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2Y4"/>
    <dbReference type="OrthoDB" id="361536at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02658">
        <property type="entry name" value="Peptidase_C19B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14385">
        <property type="entry name" value="UBA1_spUBP14_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14386">
        <property type="entry name" value="UBA2_UBP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.10:FF:000086">
        <property type="entry name" value="Ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000396">
        <property type="entry name" value="Ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000587">
        <property type="entry name" value="Ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016652">
        <property type="entry name" value="Ubiquitinyl_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041432">
        <property type="entry name" value="UBP13_Znf-UBP_var"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001607">
        <property type="entry name" value="Znf_UBP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF664">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00627">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02148">
        <property type="entry name" value="zf-UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17807">
        <property type="entry name" value="zf-UBP_var"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016308">
        <property type="entry name" value="UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00290">
        <property type="entry name" value="ZnF_UBP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50271">
        <property type="entry name" value="ZF_UBP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 14" id="KW-0645">Protease</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="9 14" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="7 14" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="10 12" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 13" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="UBP-type" evidence="18">
        <location>
            <begin position="2"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="UBP-type" evidence="18">
        <location>
            <begin position="156"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="USP" evidence="17">
        <location>
            <begin position="306"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="16">
        <location>
            <begin position="585"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="16">
        <location>
            <begin position="645"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="559"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="691"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="698"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="11">
        <location>
            <position position="315"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="11">
        <location>
            <position position="735"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR016308-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR016308-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU366025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAG0020739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="773" mass="85431" checksum="8F0FF06808956B23" modified="2023-09-13" version="1">MAACPHISSVRLSVPSHTAQIYKDECTICFDSPDNETGLDVCLSCFNGGCTDPDRYHAIQHYTKTGHPLALNIKRVKIPKDVRDGNEPPQKITKIAIVPENDADLYEYFTQVKCYECGGVEVDKTAGEIPKVVEAIMTSLSASRQSEIKAWEEEIVSCDHIRNLQQGAEKVVAAENAHCGNCELNENLWLCLVCGNLGCGRQQYGGTGGNGHGLAHFDATGHGVACKLGTITPEGTADIYCYHCNEERSDDQLGMHLARFGIKVETQQKTIKSLTELSLEQNQSFNFNMFTEDGKAFEPLFGPEYTGFKNLGNSCYMASVLQSVFNLPAFVSRYFPVDLEHLQTCSQEPGKCLQCQLAKVADGLLSGRYSTPVISESGEVQGQDGIAPGMFKSLIGRGHPEFSTMRQQDSFEFFQHLIKIISQNERTTGRDPTKTFEFSNEQRLQCNKCKKVRYSRDNTTALSIVVPATKKAGPEGEEAYESVTLEQCLDAYVAAEFLPYNCPNCKESTTANKTNRFSSFPEVLVINMRRFEYQNWVPRKIAVPIVVNEGLIDLEKYRGHGQQPDEESLPEDAPGTSSGNSDGPTFDQVALEQLQMMGFPLIRCQKALLATGNQGSEVAMDWLIQHMEDPDIDDPIVSETSSASNASPEQIAQLADMGFTDKQAKKALKETGGNMERAVEWLFSHMDTPINDDEEEGAAPAAGQTQTITGDATKKGHYRLASFISHKGPSVHCGHYVSHIKKGDQWVLFNDNKVVVDPKAPVGDAYMYIFKRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3C8</accession>
    <name>A0A9P6T3C8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_002114</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000151">
        <property type="protein sequence ID" value="KAG0021592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3C8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="85"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0021592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="263" mass="29899" checksum="C7FE403F9F551331" modified="2023-09-13" version="1">MSEKTPCPSFWRIVEETKVFINKLLDKLPASHSSLTPYDSAAGSYDSIQETINQYTSLWEVQLALGEIPGMFEENILQPCQPRNQLQSTQQPQFQPSYYQQDQSQQQMSSQQFTFPDFSSITSSSEMTSIEDFPEQSLGYYSNYECDQEEFEENDEYLWPSFSPLQNDGITKSDMRHDRKDSGIFVHDDEGAIIQISPKSRNVESRSGLLEWYGSDVDEFACDNMTIEGHISAQRSHAMGENFSCVKVGSFTLPPPLSLVSLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3E4</accession>
    <name>A0A9P6T3E4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Origin recognition complex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ORC1</name>
        <name evidence="12" type="ORF">BGZ80_001895</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">ORC is composed of six subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ORC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000145">
        <property type="protein sequence ID" value="KAG0021684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3E4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005664">
        <property type="term" value="C:nuclear origin of replication recognition complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033314">
        <property type="term" value="P:mitotic DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001025">
        <property type="entry name" value="BAH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043151">
        <property type="entry name" value="BAH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015163">
        <property type="entry name" value="Cdc6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054425">
        <property type="entry name" value="Cdc6_ORC1-like_ATPase_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050311">
        <property type="entry name" value="ORC1/CDC6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10763">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10763:SF23">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01426">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22606">
        <property type="entry name" value="Cdc6-ORC-like_ATPase_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09079">
        <property type="entry name" value="WHD_Cdc6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00439">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51038">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 8" id="KW-0235">DNA replication</keyword>
    <keyword evidence="6 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BAH" evidence="11">
        <location>
            <begin position="96"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="241"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="445"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="594"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="7"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="70"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="260"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="292"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="308"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="327"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="453"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU365058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0021684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="766" mass="86503" checksum="8AD72E1AF2547FC3" modified="2023-09-13" version="1">MVTTTQRVRRRLEKAKKVKKDILYPPSDSESEDERLEWIGEPMNKESLLSRKASNDDPEQDGANKGGPASTPSRRATRGSGLSNTPYYKGFQKGDTVYTIGDVVFLRNQQFSRKFENPHVAQILSLWETEEKEFKGDFRWFHQEEDIVKLGKHQRNGNFPETLEKGEIVYSLDDDKNDVSTVVGKCQVLSELEWEEQSKKKQKLSGKEQLSIRFCRSMVRKMTGYHILEWKGNEEMMKLKEEKEVRPKQQPRVPFSHSSPPLTATLTLPATPRIQSPKKVTAPPSRSKKRPKIEGSESEHEPEKSQSETDEGEEDGSFESEEETKKNSQKKKRVATPKKKGAKALSIVERRSRTQVVQAPTTQRVISASVPKTDFEHARNRLHVKAVPDTLPCREDEFLEIQEHLESAIEEGTGSCIYISGVPGTGKTATVHEVIRSLQVKAEEGRGNSALQDRGDCHGKNPRDSDSSSPRFHAGPLVLTTYCLDSVVLMDELDLLVTAKQTVMYNFFEWPNWQHSRLIVVAVANTMDLPERMLSNKVSSRLGLTRINFQPYTYQQLVKIVESRLEGIKAFKREAIEFAARKVGAVSGDARRALDICRRAVEIVESNVQKVEAQRRKAAEKNPFEDIGPAPEPEQVTIRTVDQAIKEMFASPNVRLIQTASLHQKLFLVALTSKLRRLGLAEVEFSEIAHAHLQMCRLHNIEPPMLSDLAAICASLGSSRCLLVESGKQDIHQRVRLSVSEEDVIMALKTDPLFRRLLDTLPSAPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3H9</accession>
    <name>A0A9P6T3H9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_001487</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000134">
        <property type="protein sequence ID" value="KAG0021893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3H9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14733">
        <property type="entry name" value="BACK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011705">
        <property type="entry name" value="BACK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051481">
        <property type="entry name" value="BTB-POZ/Galectin-3-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006571">
        <property type="entry name" value="TLDc_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24410:SF23">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24410">
        <property type="entry name" value="HL07962P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07707">
        <property type="entry name" value="BACK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07534">
        <property type="entry name" value="TLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00875">
        <property type="entry name" value="BACK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00584">
        <property type="entry name" value="TLDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51886">
        <property type="entry name" value="TLDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="2">
        <location>
            <begin position="24"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="TLDc" evidence="3">
        <location>
            <begin position="454"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="224"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="369"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="434"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="369"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="444"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="460"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0021893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="637" mass="71278" checksum="EE3BF830E66CAA77" modified="2023-09-13" version="1">MPIYSNHEVLAVDFLRLVNSSIGADVRLIIGEEQVVMHAHSLILQARSSYFARALNSDWKEGNQGVIYKPNVAPAVFERILEYIYGGRLMIDDEMVMDLIKAADELCMEDLLHGCELHALSIICRNNVLDMVQLASRHNLHQLKTECLDFIASNIDYLKKGKAILTQDADVLKEILLMDQVDMDELEIWKIAVRWAYYQRGLDWEHCPLLEFPRGSGRVIVRTTKDEATENQYQDEDDDSDESDDQFDDARVPAQKEIDEDRFRPHSQSVFQVATSNNEVVMSATVHEDLCKQILPLLPAIRFMRIPSIDFLRLIEGTGLLPVRLCNKIYRYHSVPSMADPYQISLRRRMAFSNILTKEHKEIVINWLQMTQHSPQSPTTDHNSGPSRRSMTYSGSPPNLNISTIGSPPSSSYYIPGTGPLNFPPAYSPITSAPSSPPYLGRVSSGSSSSHRSTITGSSPVSQRPQHTTFLNHVPPPKLILQYRATRDGFDAASFHRACDQRGPTLTVVRADNGTIFGGYNSSSWSSHPTGVYSTSRVNFLFTLKDREHPLRENAIFSIKGDGNAATYNKADYGPTFGAGYDLYLSTNCNLNCQSSSSLPLSYNGQGASPAALAGSCYFRVQEYEVFLVQHSMSVSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3I4</accession>
    <name>A0A9P6T3I4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-alpha-acetyltransferase 25, NatB auxiliary subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">NAA25</name>
        <name evidence="2" type="ORF">BGZ80_003132</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MDM20/NAA25 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000181">
        <property type="protein sequence ID" value="KAG0021052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3I4"/>
    <dbReference type="OrthoDB" id="1874341at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031416">
        <property type="term" value="C:NatB complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.1040">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019183">
        <property type="entry name" value="NAA25_NatB_aux_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22767:SF3">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 25, NATB AUXILIARY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22767">
        <property type="entry name" value="N-TERMINAL ACETYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09797">
        <property type="entry name" value="NatB_MDM20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0021052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="888" mass="100620" checksum="B6D882A8AC03CC4C" modified="2023-09-13" version="1">MERGNYREGIQLCNKALKKQPDFHVAKALKALAFERCGKLNEALQLCEEIQWAKPTDEPTLRTLSMVLKSAGKYEPMVKLYENASKVHPKNENLAIQWFMSLARKLDFKGQQSVALQLHKNFKKNSYMFWAIMSITLQGQNVPANQPNVLYQLAERMMSKMNTEGKVETIEELQLYLIILLGQKDRQADALGLLEGEIGVKTKAIENVELRYLRIQLLIQVGRWKDARDATMQVLKEINSDDWRTILQYFDTIFLPIQDTDLKTSENLAEARAFISELVKNEGKTPKRGPFLAQIELEKRVQEKIGDNKATVLDLLVAYFGKFGSKTCCFEDLSVYISNLDKEDALGFCKRLKETFGEKSETVKDIAIQINIARFERFIGLQSKLNSTEAMALVNKLWKLYEDALPFGKELEETERQYGDDYAIMASHILIDIHRETKSYVPLLNATFMLEHALSASKHNYQIKLVLIRIYELLGAFNCAAFIYNTMAIKHVQHDTMSHFITDRASSFGLFSEALSQLYSAHEIYHSNESETPEMIMQAYKYSTFSKMQEFIEFQSRLENSVQKMVADREMIRLEFMKEDSVKGAILWLQELEIVNLKYDAQFCESRIDNRDTTVMLNWNPKGSPSVEALTRAASQPGHVWLTLFTLVPRLLKHMAHLSPIDAEYENLVTALEKLIQSSVSENSSDHHSELTVEEARLAQIILQVSKAYQTLSIAIVAQNSNSPTKEDPAKTAATVKGHLAAAAALLKKRESVKSTGVLPWQTFHGLTSAIETVAYLNVANQCLTNLIATKANKKGVFKATSSAVQDFMVQCRQSLQAVQTDVVALRNVVKPDRIRNGLLYEICDGSSVDFVRSPSHQAHIEDKTLKIGASWMASLVNLQQEAESGML</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T4K0</accession>
    <name>A0A9P6T4K0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">AP complex subunit sigma</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">AP3S1</name>
        <name evidence="11" type="ORF">BGZ80_003404</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the adaptor complexes small subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000019">
        <property type="protein sequence ID" value="KAG0024398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T4K0"/>
    <dbReference type="OrthoDB" id="10261046at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030123">
        <property type="term" value="C:AP-3 adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030659">
        <property type="term" value="C:cytoplasmic vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006896">
        <property type="term" value="P:Golgi to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd14834">
        <property type="entry name" value="AP3_sigma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.60:FF:000001">
        <property type="entry name" value="AP complex subunit sigma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016635">
        <property type="entry name" value="AP_complex_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022775">
        <property type="entry name" value="AP_mu_sigma_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027155">
        <property type="entry name" value="APS3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000804">
        <property type="entry name" value="Clathrin_sm-chain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11753">
        <property type="entry name" value="ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01217">
        <property type="entry name" value="Clat_adaptor_s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015588">
        <property type="entry name" value="AP_complex_sigma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00989">
        <property type="entry name" value="CLAT_ADAPTOR_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AP complex mu/sigma subunit" evidence="10">
        <location>
            <begin position="1"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR015588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0024398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="161" mass="18207" checksum="3A77CF25B2F12C0C" modified="2023-09-13" version="1">MIKSVLIFNNHGNPRLTKFYQPIDIATQQALIKEIFNLISKRPDTVCNFLEGSQMLGGQDTRVIYRHYATLYFVFVVDESESELGILDLIQVFVESLDRCFENVCELDLIFHFKEVHDILAEVITGGMVLETDIGEIVAAVQEAGRLSKKPQGLLAQKSPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T4P5</accession>
    <name>A0A9P6T4P5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Nicotinate phosphoribosyltransferase</fullName>
            <ecNumber evidence="3 8">6.3.4.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">NPT1</name>
        <name evidence="11" type="ORF">BGZ80_001730</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>5-phospho-alpha-D-ribose 1-diphosphate + nicotinate + ATP + H2O = nicotinate beta-D-ribonucleotide + ADP + phosphate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:36163"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32544"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57502"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1.</text>
    </comment>
    <comment type="PTM">
        <text evidence="8">Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the NAPRTase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.21" evidence="3 8"/>
    <dbReference type="EMBL" id="JAAAID010000014">
        <property type="protein sequence ID" value="KAG0024538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T4P5"/>
    <dbReference type="OrthoDB" id="193380at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004516">
        <property type="term" value="F:nicotinate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034355">
        <property type="term" value="P:NAD+ biosynthetic process via the salvage pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.140.10">
        <property type="entry name" value="nicotinate phosphoribosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041525">
        <property type="entry name" value="N/Namide_PRibTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040727">
        <property type="entry name" value="NAPRTase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006406">
        <property type="entry name" value="Nic_PRibTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007229">
        <property type="entry name" value="Nic_PRibTrfase-Fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036068">
        <property type="entry name" value="Nicotinate_pribotase-like_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01514">
        <property type="entry name" value="NAPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003704">
        <property type="entry name" value="PRK05321.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11098">
        <property type="entry name" value="NICOTINATE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11098:SF1">
        <property type="entry name" value="NICOTINATE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04095">
        <property type="entry name" value="NAPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17767">
        <property type="entry name" value="NAPRTase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000484">
        <property type="entry name" value="NAPRT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51690">
        <property type="entry name" value="Nicotinate/Quinolinate PRTase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54675">
        <property type="entry name" value="Nicotinate/Quinolinate PRTase N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6 8" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Nicotinate phosphoribosyltransferase N-terminal" evidence="10">
        <location>
            <begin position="15"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="Nicotinate/nicotinamide phosphoribosyltransferase" evidence="9">
        <location>
            <begin position="182"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF17767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0024538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="431" mass="48333" checksum="06BEE031B8A8CA0E" modified="2023-09-13" version="1">MTSSQATSLACSSILDNDLYKFTMQQAVRQHYPNTPCDYRFTNRSPELASLPDKAIPWLNQKIQDMARVQLTSEERVFLETNCPYLTKDYLDWLQHEFRFKPEHQVKIDLHQETSINGANGNSGSAEITITGIWEEIILYEVSILALICEAYYRFGDQDWTYTGQFEAAKNKSERLVQAGAKFAEFGTRRRRDYETQRIVLEGLIAGSPLPGNAAPGQGFLTGTSNLHFAHILKLTPIGTMAHEWFMGTAAILKDASQANRVSLERWAATFPGQVLGIALTDTFTTKAFLASFKGALARDWVGVRHDSGDPFEFMEKIIHHYDHDPLVGPELRKTKKIVFSDGLNTDRAIKLQEAADAKGIQVSFGIGTHFTNDFRKADQEKVKSAAMNIVIKLHTCAGKECVKLSDDQTKESGSQKAVAEVKQQIETLWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MD71</accession>
    <name>A0A9P6MD71_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_008287</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004440">
        <property type="protein sequence ID" value="KAF9993090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MD71"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9993090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="315" mass="36372" checksum="B7C293AC916CF40B" modified="2023-09-13" version="1" fragment="single">MSNHLNQPGQWRAQMVISCRTEYNGVEYKDCFQPTDRNNGGDTGQFQEAIISPFTKEQIQDYIGQYVSLKKSSWGSEKYLQALEQIPNLQDLVKNPFILKISLEVLPRLLRTNTNFSSTRITRVQLYDEFVALWIDRGKIRLREMELSPYDKSTFKRIADSGFQQYGITYLKELVTAIYEHQNGNPVVRYSERVDRRTWKETFFSDKDGSHLLREVIPLTRNGDQYRFIHKSLLEYGLSLAVFGPSQRNEDTEVMSLESRRGSTGSALSFESPSLTERTATIDDQSLLDSPLGKRNLVGERSVLQFLTERAQQEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MDG8</accession>
    <name>A0A9P6MDG8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008152</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004334">
        <property type="protein sequence ID" value="KAF9993429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MDG8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039254">
        <property type="entry name" value="Rds1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38705">
        <property type="entry name" value="PROTEIN RDS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38705:SF1">
        <property type="entry name" value="PROTEIN RDS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13668">
        <property type="entry name" value="Ferritin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="Ferritin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040168159" evidence="1">
        <location>
            <begin position="20"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9993429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="276" mass="30130" checksum="D4475CDAB63AB2DE" modified="2023-09-13" version="1" fragment="single">MRLSIAFVASTIATAAVIAAPLNIKRGLSKTNIGVLNFALTLEHLEAAFYTLGLEKFDDDAFRSAGFLSPVREQFIHIKDHESTHVETLKVVIENAGGVPVPECKYNFPLTDIHSFVNIARALETTGVSAYLGAAANFNGDLLTGAASIATVEARQSSFLNELTGLEGAPYNFDTPLDARQVFTMASQLIESCPFNLGVEPFTQLKATLPDHGDKVMVSFEGEKHHKKTWCQFLFSNSVVVSPIEECAVPSDAIGYFYLIITDTARPITFNDDRHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MEP3</accession>
    <name>A0A9P6MEP3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007597</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003916">
        <property type="protein sequence ID" value="KAF9995132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MEP3"/>
    <dbReference type="OrthoDB" id="2405996at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9995132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="332" mass="37110" checksum="C06A925F9C41E7A6" modified="2023-09-13" version="1">MTQLLESTRNYLKVSTKLGRRLSSYREDSSASETSLHVSSAENIKRKQMNRLSSLFTLETRKNSVSSEDRPAISILPSKVEPEVQDQPRNDNKKRRSSSSRKSTLSQPPSTLRTSQYMDHNDVPRGRSPTLSVASTMRSVASSSATSYDTRPSDYRSVDEYNTHVWRRTLLEESIMQSLNLGYGQPAPRSDRPLSQRRSRSLKRNTTGRSRKDLPPTDPQAGRKTVIDRNTSAPNRILVPQQEKAVNKNNPYQMLLNPSTSNITHSFASFTLELPEHQVTHVLSASAVPHLFTLKTVNGPSPSPHVLTGKAAIEQENMDPRHMHQAVAAAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MEQ3</accession>
    <name>A0A9P6MEQ3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HAMP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_007584</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003909">
        <property type="protein sequence ID" value="KAF9995172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MEQ3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004673">
        <property type="term" value="F:protein histidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071474">
        <property type="term" value="P:cellular hyperosmotic response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06225">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1530:FF:000002">
        <property type="entry name" value="Two-component osmosensing histidine kinase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1530">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.950">
        <property type="entry name" value="Methyl-accepting chemotaxis protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45339">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45339:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18947">
        <property type="entry name" value="HAMP_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58104">
        <property type="entry name" value="Methyl-accepting chemotaxis protein (MCP) signaling domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="domain" description="HAMP" evidence="3">
        <location>
            <begin position="50"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="3">
        <location>
            <begin position="142"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="3">
        <location>
            <begin position="234"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="3">
        <location>
            <begin position="326"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="3">
        <location>
            <begin position="418"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9995172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="463" mass="49452" checksum="3B0BDAC6271818DA" modified="2023-09-13" version="1" fragment="single">MVDQLSTFAVEVTRVAREVGTEGKLGGQAEVEGVDGTWKELTDNVNTMASNLTTQMRDIADVSKAVAKGDLTKKITVDVKGEILDLKNTINSMVDQLSTFAVEVTRVAREVGTEGKLGGQAEVEGVDGTWKELTENVNTMASNLTTQMRDIADVSKAVAKGDLTKKITVDVKGEILDLKNTINIMVDQLSTFSAEVTRVAREVGTEGKLGGQAEVEDVGGTWKELTDNVNTMASNLTTQVRDIADVSKAVAKGDLTKKITVNVKGEMMDLKHTINTMVDQLQEFATEVTRVSLEVGTEGKLGGQAVVEGVSGTWKELTDNVNTMASNLTTQVRSIAEVTTAVACGDLSKTIDVVAQGEISELKRTVNSMVEQLRTFAAEVTRVAREVGTEGKLGGQAQVKGVDGTWKELTDNVNTMATNLTTQVRSIAEVTTAVACGDLSKTIDVQAQGEISELKLTVNSMVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MEX9</accession>
    <name>A0A9P6MEX9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007543</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003887">
        <property type="protein sequence ID" value="KAF9995323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MEX9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9995323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="74" mass="7667" checksum="1E67C5EE8E1A8C25" modified="2023-09-13" version="1" fragment="single">MTPGVKAVVTEQTLKEDEPQSEDAKAPIAPQLLPPLPSFKALALTTPPNDISVPAPVNPNNSVLPETASLALAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MF01</accession>
    <name>A0A9P6MF01_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_007545</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003888">
        <property type="protein sequence ID" value="KAF9995322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MF01"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9995322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="105" mass="11900" checksum="B1EF9F7B21A1610C" modified="2023-09-13" version="1" fragment="single">VAINRKGSYQPRLKFRCLLENRKSRIVDGDTIASIGSNLPNFEADPEAPEVYETAHWDALNGFCNDSEMKRLRHDWDAGRVHRAEFVLLTDGYLFVRGCGMRGTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MFA9</accession>
    <name>A0A9P6MFA9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Arm-like repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007366</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003752">
        <property type="protein sequence ID" value="KAF9996025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MFA9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056251">
        <property type="entry name" value="Arm_rpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23948">
        <property type="entry name" value="ARM_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arm-like repeat" evidence="1">
        <location>
            <begin position="1"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF23948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9996025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="544" mass="62223" checksum="DE1E9755F3B6F395" modified="2023-09-13" version="1" fragment="single">MRRTGKVTQGISGVVSAVKALDLMGFIEGLQNVQQGLVGAEKTIGLVSDACTNAMGLVEDGQELLKSLKECFSFKRRGLWYPALRGLDRLIQEGRLVEFEELVRKAPCQNDPIFRWGVCQRLGEIATNTIWDLNTRKCAVGFLRQLYKDDASKDQQLVTKQWILYILNKLAESSKDIIEGSVQELLHEAQTHSSFSKGVLYHGCESDNPVLHLIMITPTPMESPLLNCVQNKPDVETPLRQLKLERLKGQGGDVYISPRAKVTQRATDDFDLTSKVQEFLTSDRKVFLVLGDSGAGKSTFNRALEISLWDNYKVNGRIPLFIYLPAIEKPERDLITERLRRANFTESQILELKVYHEFILICDGYDESQQTRNLYMSNQLNQPGQWRAQMVISCRTEFIGVDYKDIFQPTDRNNGRGTGQFQEAIISPFTKEQIRDYIGQYVSLQRSQWSLEDYLQALEQIPNLQDLVKNPFLLKISLEALPQLLEANTEFSSTHITRVQLYDEFVAQWIDRGKIRLGEMELNPYDRNTFKQMMESGFQEHGIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MG38</accession>
    <name>A0A9P6MG38_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mediator of RNA polymerase II transcription subunit 25</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006883</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003429">
        <property type="protein sequence ID" value="KAF9997987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MG38"/>
    <dbReference type="OrthoDB" id="7690434at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="217"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9997987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="236" mass="26271" checksum="2F718F61431FB8D7" modified="2023-09-13" version="1">MPAKNSELQRLAEAHSLPFIHIYPSAGNSVENSSIFDVLTKNMGIKKVVATVRFPQIGPSAGMVLIYNEKRLNLIGLLFLKVPIPNLTMPTTIQQQSPQQIGQQAVINAAASSNPVGAINPQQQPFLIQAQMIQQHKNRLLQQQQQHIAFQQQQNPSQAGQANVIVNNPIQAMGIQGSTTGAPNMIQNLQGMPFGSPLMMQRLQQIQQQQQQIMHQQQQQQQQQQQQQQQQDPNQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MHC5</accession>
    <name>A0A9P6MHC5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_006322</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003113">
        <property type="protein sequence ID" value="KAG0000675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MHC5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031901">
        <property type="term" value="C:early endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15760">
        <property type="entry name" value="FYVE_scVPS27p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46319">
        <property type="entry name" value="ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46319:SF3">
        <property type="entry name" value="ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FYVE-type" evidence="6">
        <location>
            <begin position="179"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="21"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="75"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="31"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="100"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0000675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="343" mass="37484" checksum="03659D329C6F9695" modified="2023-09-13" version="1">MDVYSLTKKQRPTHLTRAEVDKTGAMALPDQQHSQLSQRQQQQQQQPTSLGAPPTLKDIETKHSQLPPQYRQAVLEQQQREHQQRILQQQQHGSPKVDSQRQSVSVSSTPNGNINANGAGNGAHKGAGNSTHPRISSAPLLSSHRPDRSNSHSSTSCSGPSRAHWKPDSSTQVCTWPGCLREFGFFDRRHHCRKCGDIFCSTHCSKSIPLDQALDFNPAMGVMSRACTGCFEAYEQWQGLAPSTTTLGQPGSRGAFGFVSGSQTAGEYSTNLSSGMNKQTGSLSPIIGKKHAEGLSSEALGREDVVRLPKSTSENIAIKTRPVQDTTMMPMPSVPHDWSWSTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MI07</accession>
    <name>A0A9P6MI07_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Elongator complex protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ELP2</name>
        <name evidence="12" type="ORF">BGZ80_006387</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="3">tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the WD repeat ELP2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003151">
        <property type="protein sequence ID" value="KAG0000320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MI07"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033588">
        <property type="term" value="C:elongator holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000400">
        <property type="entry name" value="Elongator acetyltransferase complex subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037289">
        <property type="entry name" value="Elp2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44111">
        <property type="entry name" value="ELONGATOR COMPLEX PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44111:SF1">
        <property type="entry name" value="ELONGATOR COMPLEX PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="7 11" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="52"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="108"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="260"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="444"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="714"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0000320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="714" mass="78815" checksum="2CFC006706CFD89D" modified="2023-09-13" version="1" fragment="single">MEVTQEYISVGCNRLTQAFAWGADGLAAFGAHHAVALYFPMDSQRRGVRATLQGHSARVNCVTFLNRGHELDQKNVAIVSGSADKTARIWKKTNGNDDETSWICSAVLEGHTGSVVTIGVVRARSIHDNGKDLLATGSGDGTIKIWERKEIDDTKDEVTCIQTIQVGKKYAQSIAISYLPNTTVPIMAVGSTDNRISIYVMQSNQFDKVLSLQGHDNWVRSLDFATFTKEGNTVSLRDPTDSVVSGNASHHHTLQDGDLLLASGSQDKYIRIWRISAVDKTESANAEEDSAKTESEGALTQDMLRSLEEMSKSGAQLSTKAHLIDVVLDSAETKRFSVIFEALLLGHDDWVYTINWQPPTLLNGKYHQPMSLLSASTDKSMMIWKPDEATGVWINNTQVGEVGGNTIGFYGGQFGSDGRWILAYGYNGAFHIWKNEGNEIGVPASGHYASVQGLTWDPTQSYLVSVSLDQTARLFSPWKHTDEKTGAAVSTWHEIARPQIHGYDAQCITFSDKWTFVSGSDEKVLRVFDAPQTFVRSLAQLTGDQTILSEESSRPVGANLPALGLSNKAIFENDIAAMVEAQETEDYLSHQAYVSTGATPTSLIETLTHPPFEEHLLQHTLWPEVEKLFGHGYELMCVDASHDGKWIASACKAHTPDQAVVRLFDAKTWKQTPTPLVSHTLTVTKVLFSHGDKYLLSISRDRLWSLFERVEDEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MIF7</accession>
    <name>A0A9P6MIF7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_006143</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003019">
        <property type="protein sequence ID" value="KAG0001636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MIF7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0001636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="200" mass="22033" checksum="1452D7FDEEE3BA7E" modified="2023-09-13" version="1">MADVIAGSAGKEAAKAVAAGGISAMAQGAGKGLIEAGKKDPEPKKTKLRVVTVNQENMVKQVHAACKKFKEEIPLQAIYDAYGTLTLYWDKYLKAGLPWVDANIAVEAQVKEFEKKKLFQEGQDGLWKRVDDQTKAVISLIELKQPVPATVQKIADMYTANQPAGLRCIQGKIDEHALLLEVQLHALQELMRDEVEMKEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MIV3</accession>
    <name>A0A9P6MIV3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005706</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002803">
        <property type="protein sequence ID" value="KAG0003997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MIV3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.430">
        <property type="entry name" value="Galactose-binding lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="475"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="475"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="667"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0003997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="667" mass="72212" checksum="C791887111EA6808" modified="2023-09-13" version="1" fragment="single">GSNDTRQAITIKSTSNNGQACAIGFDVGAYVGQSNGGKTGGIPRAYVATYDPGYDNIFRMIKTLYSQSTTTGLVTSWPVPGNKGVHFAWTYDIDAQDSYVLAYECAKDLQSRGMKGTINWQTKLVKDAYDVAFFSEFYRNISLVEALGNMELASHSVSHSPNLEQFAVGTGKEIWDGTKYQEDNYFPFIGECMNATSGVWTTSIPNATTCETPNDILYFFTLGGSILGEARVSKYILEAISIVSAKVQSFRTGHLLYPDTLPQILVATGYKYSSSGASNDRNSHMPYQAFYNQAYNQEVDLLEFPLSASDEDGQINGDFYAPGTGGYTDGSYAWQQYQVVQKVAKYGGQYTFLIHPTSHIIPDVVQTLFSDKLAFQQTLAPLVANISYFDTMSGRGDFHNARIASGIDVAVFGNVVTVTITLTKPIVDLTLRVPTAWAFMSSTVGVQATSGAVTLLNTAPAGTVTLNFQTSGTVTATTNPAPGAPTTTSTISMATPTIPAPTPTPSSPRVVDDFSDPSRYSSEQNALGFYVGDDGTAASRISVQADWLLLNVNNNTYWYSNLGPANTCNDYSSFTKLSLAIRYPTTKRIGFSVVIQDTETTACTGLIQHSFDVTALINSATAGSDGWFHLDIPLTNFNGTDLTRMRAVALTSFASACQVEVDYIYFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MJI3</accession>
    <name>A0A9P6MJI3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_005679</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sideroflexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002797">
        <property type="protein sequence ID" value="KAG0004063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MJI3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015075">
        <property type="term" value="F:monoatomic ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990542">
        <property type="term" value="P:mitochondrial transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004686">
        <property type="entry name" value="Mtc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11153">
        <property type="entry name" value="SIDEROFLEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11153:SF6">
        <property type="entry name" value="SIDEROFLEXIN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03820">
        <property type="entry name" value="SFXNs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="48"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="170"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0004063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="229" mass="25160" checksum="58A765E617146690" modified="2023-09-13" version="1">MLVAAGMLMPNPSVRSIIFWQWTNQSVNVAFNYANANKTIEMDMKETAVAYMSAVTTSCFLAVGLNQLVPKLTSISPGVRSVLTRLVPFTAVAAAGTVNVFLMRGKEISEGIDVYDHEGKSVGKSQKAGMSAITQVAISRILTNFPVLTIPPLILAQWERTTWSQQYPRALIPLNLAVITLCLMTALPLAIAAFPQYANVDVKKLEERFWHLKDSKGEPIKTLTYNKGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MM11</accession>
    <name>A0A9P6MM11_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_004635</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6 8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="6 8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="6 8">Probably binds two magnesium or manganese ions per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the DNA repair enzymes AP/ExoA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002342">
        <property type="protein sequence ID" value="KAG0007461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MM11"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003906">
        <property type="term" value="F:DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008311">
        <property type="term" value="F:double-stranded DNA 3'-5' DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004808">
        <property type="entry name" value="AP_endonuc_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00633">
        <property type="entry name" value="xth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22748">
        <property type="entry name" value="AP ENDONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22748:SF6">
        <property type="entry name" value="DNA-(APURINIC OR APYRIMIDINIC SITE) ENDONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51435">
        <property type="entry name" value="AP_NUCLEASE_F1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0464">Manganese</keyword>
    <keyword evidence="2 6 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="10">
        <location>
            <begin position="11"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="41"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="5">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="178"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="7">
        <location>
            <position position="83"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="7">
        <location>
            <position position="150"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA substrate" evidence="7">
        <location>
            <position position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR604808-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR604808-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR604808-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0007461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="189" mass="21374" checksum="D3FA0BF4DB404FF6" modified="2023-09-13" version="1">MFSKTTPISVTEGLSTHPDPSCTRGRIVTLEFPTCYVLGCYVPNAGQGLVRLKERMVWDKAMKEWLLQLKGKGKHIIWTGDLNVCHKPIDLRNPKTNTMSAGFTKEERAGFSEILDEVDLVDTFREIQGEDESVAGQFQCRVKGIGWRLDYFVTDKDMYKDRVVESVIREECYGASDHVPVVLVVKGDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MME7</accession>
    <name>A0A9P6MME7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Pentacotripeptide-repeat region of PRORP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_004511</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Regulates mitochondrial small subunit maturation by controlling 15S rRNA 5'-end processing. Localizes to the 5' precursor of the 15S rRNA in a position that is subsequently occupied by mS47 in the mature yeast mtSSU. Uses structure and sequence-specific RNA recognition, binding to a single-stranded region of the precursor and specifically recognizing bases -6 to -1. The exchange of Ccm1 for mS47 is coupled to the irreversible removal of precursor rRNA that is accompanied by conformational changes of the mitoribosomal proteins uS5m and mS26. These conformational changes signal completion of 5'-end rRNA processing through protection of the mature 5'-end of the 15S rRNA and stabilization of mS47. The removal of the 5' precursor together with the dissociation of Ccm1 may be catalyzed by the 5'-3' exoribonuclease Pet127. Involved in the specific removal of group I introns in mitochondrial encoded transcripts.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Binds to mitochondrial small subunit 15S rRNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CCM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002295">
        <property type="protein sequence ID" value="KAG0007558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MME7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447">
        <property type="entry name" value="OS03G0856100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447:SF17">
        <property type="entry name" value="OS12G0638900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13041">
        <property type="entry name" value="PPR_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13812">
        <property type="entry name" value="PPR_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="PPR" evidence="5">
        <location>
            <begin position="159"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="5">
        <location>
            <begin position="208"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="5">
        <location>
            <begin position="243"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="5">
        <location>
            <begin position="339"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="5">
        <location>
            <begin position="444"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="5">
        <location>
            <begin position="479"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00044493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0007558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="589" mass="66821" checksum="5AFBCFACA18870F9" modified="2023-09-13" version="1" fragment="single">TTALDNLIDDSVTKDKPDFLLAPEVAPLSLQTVDPKFFDLTIIPPEPIREFRNLYDQIAQSKDTNDHEKFLSVYRSIADDIDLLLQFQPIDFMIAMNSCRDLLHMIPRMHRILQDVSKTSHAQVSEIYNIILKAYSKMSDFKSCSNMIDKMRAQKMGLNTTTYHIILDTCKHARKLKDAQGILAQMRKKGVEAREYFEEMPLLGLDRDVAHYNALLNAYAHAGDATGAKRVYQLMEDDGILADQYTYTAMVKAYRTCNRFPEAIHFLKKLREAGVKPNAKVLAAMGEEPLEIVEECARSEVPISQSGFNMLITRAIKSNQFPQVPHLLEEMQKAGHRPDVFTFTAMVDANIKMGKYQEAKEIFMAMQRANIQPDVIAYSAMISGALSQVGVQESMVILKAMMDDGLLPNLHTFNSLLSASVGEIGVEGFKVIREAMQSLHIRPDHRSFNALLSAYALEGDMDEMLDALEDMKRSRVPPDNLTYSILISGYLQNGDLRFAMEWYYKMIESGHVPTTRVANNLMAALHGSGQGQQVLLLWREMDRMNVGKNDQSFEIALEACEKFGLHDDKLRIEKELNIYLSGGRKYYDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMK6</accession>
    <name>A0A9P6MMK6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Alpha-ketoglutarate-dependent dioxygenase alkB 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ALKBH6</name>
        <name evidence="10" type="ORF">BGZ80_004372</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the alkB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002232">
        <property type="protein sequence ID" value="KAG0007680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMK6"/>
    <dbReference type="OrthoDB" id="412814at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1520">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027450">
        <property type="entry name" value="AlkB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032862">
        <property type="entry name" value="ALKBH6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46030">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46030:SF1">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13532">
        <property type="entry name" value="2OG-FeII_Oxy_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="9">
        <location>
            <begin position="20"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="66"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="75"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0007680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="176" mass="19852" checksum="68DEF2856AA61D62" modified="2023-09-13" version="1">MFPRFQESGVFDGLDAPHRVPNHCLVNEYLAGQGIMPHKDGPAYLPTVATISLSSHCLLEFYKVPEEGEKDSNEGEQPSNSSTTTNEKHSQEPVFSLLVQPRSLLVLKEDVYNKYMHGIREVTLDDLRKSNILNLNEALPEGINDTNALLERGTRISLTFRIVQKTLSSKKIFLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMR9</accession>
    <name>A0A9P6MMR9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Arylsulfatase</fullName>
            <shortName evidence="2">AS</shortName>
            <ecNumber evidence="2">3.1.6.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Aryl-sulfate sulphohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_004483</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>an aryl sulfate + H2O = a phenol + sulfate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17261"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16189"/>
            <dbReference type="ChEBI" id="CHEBI:33853"/>
            <dbReference type="ChEBI" id="CHEBI:140317"/>
            <dbReference type="EC" id="3.1.6.1"/>
        </reaction>
    </comment>
    <comment type="PTM">
        <text evidence="3">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the sulfatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.6.1" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010002284">
        <property type="protein sequence ID" value="KAG0007588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMR9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004065">
        <property type="term" value="F:arylsulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005539">
        <property type="term" value="F:glycosaminoglycan binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008449">
        <property type="term" value="F:N-acetylglucosamine-6-sulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018958">
        <property type="term" value="P:phenol-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16147">
        <property type="entry name" value="G6S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012083">
        <property type="entry name" value="Arylsulfatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43108">
        <property type="entry name" value="N-ACETYLGLUCOSAMINE-6-SULFATASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43108:SF8">
        <property type="entry name" value="SD21168P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000972">
        <property type="entry name" value="Arylsulf_plant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040335683" description="Arylsulfatase" evidence="4">
        <location>
            <begin position="24"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase N-terminal" evidence="5">
        <location>
            <begin position="35"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="3">
        <location>
            <position position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR000972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000972-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0007588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="566" mass="63946" checksum="CA6DC598FD4EC30D" modified="2023-09-13" version="1">MKTISFLAVLPVAIISFSQLVAASSGSHGHQKQKPNFLVFLTDDQDRRLNSLDHLPLVKKYIRDEGTEFTNYYTTTAMCCPSRVSLWSGQFAHNHNVTDESPPHGSYTKFVSQNLEQNWLPLWLQEAGYSNNYIGKFINGVSPTLKRAPKGFDKDHWEPLVAPNIYTFYSPVFSTNDGPLEAHTGVYQTDIISDKSIAILDGLAKNKSNPFLFVISPTAPHDEVWFDDKGTVFTPPVPAKRHEGLFPGAKAPRHPSFNPDKNDKVSWIGTLPKLNDSEVERIDAIYRARLQSLQATDELVERIIKRLEHNGQLDNTYIVYTTDNGYHLGTHRMFAGKQTPYEEDTNIPFIIRGPGIAKNKKSNAVATHTHFPATVLQLAGLPIPDELDAHSIPVLADRSVYGKDQPTEAFSVEFWSNAFLENATATFTTNSYKSVRLIGQGYNLLYTIWCTGEKEYYDLVEDPFQVKNIYKHTKQSFLDRLDALLNVLRTCKGPTCRDPWSVIHATTNSKSKSKNHGSQKEVRSLKDALNKKYDEFYAGLPRFSFKNCLPYYLSANEVETPEHSEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNE7</accession>
    <name>A0A9P6MNE7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">HIT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_003516</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001933">
        <property type="protein sequence ID" value="KAG0008383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNE7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001310">
        <property type="entry name" value="Histidine_triad_HIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12486:SF5">
        <property type="entry name" value="ADENOSINE 5'-MONOPHOSPHORAMIDASE HINT3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12486">
        <property type="entry name" value="APRATAXIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11969">
        <property type="entry name" value="DcpS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00332">
        <property type="entry name" value="HISTRIAD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51084">
        <property type="entry name" value="HIT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HIT" evidence="6">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Histidine triad motif" evidence="4 5">
        <location>
            <begin position="75"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-AMP-histidine intermediate" evidence="3">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR601310-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR601310-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0008383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="123" mass="14218" checksum="9BF9BED8A3EE55AE" modified="2023-09-13" version="1" fragment="single">DDEIAAFQDIKPAAEAHILIVPVAHIENIKSLNSEHIGLLEKMHQKGIDFLKERGHDPEVSKLGFHVPPFNTVDHLHMHVLGGQFKSKFRRLKYETGRMWYMDLTQLKTDLDKQQRVQQGARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MP30</accession>
    <name>A0A9P6MP30_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nucleolar protein Dnt1-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_003037</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001780">
        <property type="protein sequence ID" value="KAG0008808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017956">
        <property type="entry name" value="AT_hook_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018844">
        <property type="entry name" value="Dnt1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16148:SF14">
        <property type="entry name" value="MYND-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16148">
        <property type="entry name" value="NF-KAPPA-B-REPRESSING FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10407">
        <property type="entry name" value="Cytokin_check_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00384">
        <property type="entry name" value="AT_hook"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nucleolar protein Dnt1-like N-terminal" evidence="2">
        <location>
            <begin position="32"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="248"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="298"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="773"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="935"/>
            <end position="993"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1075"/>
            <end position="1101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1114"/>
            <end position="1197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1221"/>
            <end position="1241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1261"/>
            <end position="1375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="106"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="128"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="251"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="272"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="345"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="381"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="629"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="660"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="720"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="773"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="811"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="836"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="937"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="975"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1082"/>
            <end position="1095"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1116"/>
            <end position="1150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1157"/>
            <end position="1179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1269"/>
            <end position="1284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1298"/>
            <end position="1321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0008808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1375" mass="149442" checksum="75CF5BE974257674" modified="2023-09-13" version="1">MESAGSKFRLQVNLPVHNHCIYGPQHGGVTHKRLLVVASPNSTIKELRLNIDSRFEKLFPDLKGVFRVRRLTNKEKFELDDDQLVGEVFDPVDTLIALGPDPPQQNKKNANNNKHNSNNNKNDKKNNNKANNKNNNNSNINNINKHNNNNNNNNNNNKGNNNNNNKNNKNSNANKNPTPDQLKRKREETPSEIQNPLVPPTVHSSKKMKQQRDAAAGVPKSPSVPNPGQGKRPQNTVEQFNAGITSTVVNGKTKTPTGGPGHAPKSVSKANTPAISTSIPSTPQTTLSAQLSTIALAIDSDSDSSSDSDSSSDSDSSSDSDSSSDSDSSSDSESSSDSSDKDSSPTAIATHTPVSEGNSAQQPVATSKTNEKTGKSVAGDKALKETENLARQAAEMKQKREETAKKRKETMAKKRMEAEELELKMAEEMKLKEAEENEKKMLEDKALKEAEEEKHKEAKEQALKEAEEKKQMEAAEKRKQAAEKRKEAAAKRKEAAEKDKKEAEEKRKEAEEQELKKIEEAQRREAEELAKKEAEELAKKEAEELAKKEAEELAKKEAEELAKKEAEELARKKAEELAKKEAEGLARKEAEEKKRKEAAEKRKEAAARRKEAAEKEKEKKVAEKQTSQETERKRKETEQQELEQAEETERKEADVMAQKEAGEKKRKEAAEKRKEAAEKRKEAAEKRKEAAAKRKEAAEKEKEEAGKLEKAVDQSMDIDEPSKEEPKIPSKKTKAEQEVKVAKGAAKRPARNAAAKAAELLLEFKTVNTKYLQEMNGSSDDNEAKSSQAPNTTDDINANERITIEVPPSPSKKRVGRPSKNKTQDTEETQDPTEPPLKKREGRAPKGIDTELTPEVKDTEAKLTDKNPELAPKGTSAEPVPKGNDMELTTESPVKKRRGRPPKVKNDIAVETSGAKPSDLSTVEEATAVALDASVRIQDSSLLSSSGIPTQTTDTVTEPADDSGIFSDQEKEPSMDDSDSDSSSEDDPCYMESEQIIPPVIASSRHPISIPATGMLNANGSSVSVKQGRVALLGLSTASPKPTPATTPSKNAITAVAKVIPTPSPSAIENIFEDAYDDSQQLEDRESEKDGEPLIHHRKRPLATKVSVPAALLNIEIDKGTPKNDEITVVMKEETAGKDKTGHHSDESNRSDNNSSSDDDDSSDDDSTSSDSDDEEDADEGKNKGIGKMSSTSNTFSSSILGGISILGGAYSARTRNNNAVTTATASSTSSSGNDGSYVSLSDISSMNLLPNLRSLSVMTAQNRASKKGTIGSTIPSPTSSTTSFTVNRASGHRVTASDEDSDEESYDDEDDDDDTDSSEDESSKKTKSGPQVKIAGQKRKAVGGAASKLGVNGGARGVTSVKRKKKGALDAMFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPI5</accession>
    <name>A0A9P6MPI5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_003046</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001785">
        <property type="protein sequence ID" value="KAG0008795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPI5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061671">
        <property type="term" value="C:Cbp3p-Cbp6 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034551">
        <property type="term" value="P:mitochondrial respiratory chain complex III assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037653">
        <property type="entry name" value="Cbp6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28250">
        <property type="entry name" value="CYTOCHROME B PRE-MRNA-PROCESSING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28250:SF1">
        <property type="entry name" value="CYTOCHROME B PRE-MRNA-PROCESSING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20180">
        <property type="entry name" value="UQCC2_CBP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0008795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="138" mass="15570" checksum="65794F3C328609E9" modified="2023-09-13" version="1">MSSAATPSTKTIVSLYRSYLRVINKWPADPIRPTRNMKTALRSQVTESFRSPITGANNDTLSAKIADAKIQLEALQKITHNEFKQKYPLSSKLLTPASNPNYYSKLVDMLEKETAKKNFEAVGKKGPSFFQRLFRTAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPT0</accession>
    <name>A0A9P6MPT0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 12">Malate dehydrogenase</fullName>
            <ecNumber evidence="3 12">1.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BGZ80_002170</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7 12">
            <text>(S)-malate + NAD(+) = oxaloacetate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21432"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.37"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the LDH/MDH superfamily. MDH type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.37" evidence="3 12"/>
    <dbReference type="EMBL" id="JAAAID010001527">
        <property type="protein sequence ID" value="KAG0009673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPT0"/>
    <dbReference type="OrthoDB" id="4069699at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030060">
        <property type="term" value="F:L-malate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006108">
        <property type="term" value="P:malate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01337">
        <property type="entry name" value="MDH_glyoxysomal_mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000013">
        <property type="entry name" value="Malate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.110.10:FF:000001">
        <property type="entry name" value="Malate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.110.10">
        <property type="entry name" value="Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001557">
        <property type="entry name" value="L-lactate/malate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022383">
        <property type="entry name" value="Lactate/malate_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001236">
        <property type="entry name" value="Lactate/malate_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015955">
        <property type="entry name" value="Lactate_DH/Glyco_Ohase_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001252">
        <property type="entry name" value="Malate_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010097">
        <property type="entry name" value="Malate_DH_type1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01772">
        <property type="entry name" value="MDH_euk_gproteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11540">
        <property type="entry name" value="MALATE AND LACTATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11540:SF16">
        <property type="entry name" value="MALATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02866">
        <property type="entry name" value="Ldh_1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00056">
        <property type="entry name" value="Ldh_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000102">
        <property type="entry name" value="Lac_mal_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56327">
        <property type="entry name" value="LDH C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00068">
        <property type="entry name" value="MDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10 12" id="KW-0520">NAD</keyword>
    <keyword evidence="5 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Lactate/malate dehydrogenase N-terminal" evidence="13">
        <location>
            <begin position="2"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="Lactate/malate dehydrogenase C-terminal" evidence="14">
        <location>
            <begin position="147"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="178"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="8"/>
            <end position="14"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="117"/>
            <end position="119"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0009673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="332" mass="34734" checksum="8F8929BFBFFDD319" modified="2023-09-13" version="1">MVKVVVCGAAGGIGQPLSLLLKQSDLISHLALYDIVNAAGVAADLSHINTVSKVTGHVGKDSLAEALRGAHTVVIPAGVPRRPGMTRDDLFKVNAGIVRDLAQACAENCPKAFILVISNPVNSTVPIVCEVLKKANVFDPRRVFGVTTLDVVRSSTFVSQVKPQFEPHSNRVTVVGGHSGATIVPLLSQIKQLSFTPEEIKALTHRIQFGGDEVVKAKDGAGSATLSMAAAGARFTIALLEASVRGKRGIVESTYVHLAGNPGAEWNLRSTGLEYFAQDVELGPDGVANVLALPNLSAEEQSLVKTAIGELKGNIAKGINFIKEGSGPASKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQW4</accession>
    <name>A0A9P6MQW4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cytosol aminopeptidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_001944</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001463">
        <property type="protein sequence ID" value="KAG0009914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQW4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011356">
        <property type="entry name" value="Leucine_aapep/pepB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000819">
        <property type="entry name" value="Peptidase_M17_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11963:SF48">
        <property type="entry name" value="DIPEPTIDASE B, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11963">
        <property type="entry name" value="LEUCINE AMINOPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00883">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00481">
        <property type="entry name" value="LAMNOPPTDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00631">
        <property type="entry name" value="CYTOSOL_AP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytosol aminopeptidase" evidence="5">
        <location>
            <begin position="110"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0009914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="291" mass="30898" checksum="37AC9CB82FED736B" modified="2023-09-13" version="1" fragment="single">PRHHPRVVKFEYKSDEPSKVKENLYFVGKGVTYDTGGADIKAGGVMRGMSRDKCGAATVAGFMATLAELKPKHVNVTAILSLVRNSVGSNAYVSDEVIYSRAGVRVLVGNTDAEGRMVMTDPLCECKERVLADRQAGINIPSRLFTVATLTGHAIRAYGPYGICLDNGPARKAGISTRIQAGGHILGDPFEVSTLRREDYACVAPGSAAEDVVQANDKASSASARGHQYPMAFMSIASGLNNFGLDKEKKDQIAYTHVDIAGSAEELSGVGFSLPEVTGNPVPAFASTFLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQX2</accession>
    <name>A0A9P6MQX2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">LRR-containing protein second PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_001363</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001306">
        <property type="protein sequence ID" value="KAG0010580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQX2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057334">
        <property type="entry name" value="PH_2nd_LRR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051279">
        <property type="entry name" value="PP1-Reg/Actin-Interact_Protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24112">
        <property type="entry name" value="LEUCINE-RICH REPEAT, ISOFORM F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25353">
        <property type="entry name" value="PH_2nd_LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LRR-containing protein second PH" evidence="2">
        <location>
            <begin position="382"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="124"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0010580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1138" mass="126110" checksum="558222371C575F0B" modified="2023-09-13" version="1">MIGVPPPLSLPDPLLGDLGDPDYAEYYTSDVGILSSPQILPGQYMQSPVNSGPINPRQPYYPQSSESITSNGKQGQSACLPSPHMSPVTSPQQIDFSSLSLNDSARSGGNGNASVTNRVRAHSTSLSTVSTDDSIASRNSLVPRGYSDPIAVRPDDFYAGQPTVPIEPFLMPMQDQFPADSLILFGGTAAHSEGSLFRKDSKEYLMLTNSSLLKYKSMEKASKVFGNQSVWSSTSGHQILTPQQTSLISKDHRLISLNSIVGVHTLKTQGADVQIVIEYLVSISSQPATMHFTPSPDQVEPWLNELRQGCNYHANQAGLIPKGTRQRQWVVEKMQEDYIALPTNVAEDHPTALAAGGMWRAYFKSQKIKGVPVQENAPAETKVALEGKVVVIAVGTSFIHILPHNLGNGSTKDDLKDERAILQYPILTVRSIQYKEKDDNFTICFGTTLRQRTVVITFSSARAREIIIAIRARVESLRWLYPLTRKGIELSLSEGLSRPIPVPSKEYMADLGFDDLLRAECYAMGVDRRIYNNVQIDGFVITVGKVGDTPETKRDYSVDEMKCLLRALRFNTTFKEISFRDISFGALQKTKTLKDGTLRYGLRPDQEFYELIMGNPQIRSLDLHNCQLDTSTIGSIGRAIRDGYSAGLRLEALDLYGNNASDGADVMMLAKGIVKHAGTLHSLDVGNCQITGDGINQIMHAFVANPDVASHLLETFAIHNNSESKVNSFILDMFLKHSMRLESLNLSELTSWSKSPILMAETLGNCGGCLKHLDLSGMALHPTTLEQILAWLSSPGCESLEQLKVEGCGLDGNQFASILDAVCQGGNEKVEVLAGRNLLSDGQDLPQSLVSVLSNGETATSLGLRQTCWSEQALRQLFVSLSQNFTLKKLDISSVSLASSRDPDVETCKLLGQMLASPASRLEELYIQGEETAELTSRIGKNLWRSFEGLGNSRYLTKLDVRRNRFKDEGAMALAEALRVNQSLNWLDMDENDVTMDGFNAILSAFHQGGTEQVPTSSRYYNTTLAYFVTPVKDVDKQTEMLKELMVDSYKSEQETRFLLINSTGKDAREWKERLAQIIRQRNQNSEAIARLERAIQGIIAVVDRNKAAMDAVIRDRERRRERERDRELLQQRREGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MR98</accession>
    <name>A0A9P6MR98_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">tRNA wybutosine-synthesizing protein 4</fullName>
            <ecNumber evidence="5">2.1.1.290</ecNumber>
            <ecNumber evidence="4">2.3.1.231</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">tRNA(Phe) (7-(3-amino-3-(methoxycarbonyl)propyl)wyosine(37)-N)-methoxycarbonyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-O)-methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">LCMT2</name>
        <name evidence="14" type="ORF">BGZ80_001208</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>7-[(3S)-(3-amino-3-methoxycarbonyl)propyl]wyosine(37) in tRNA(Phe) + S-adenosyl-L-methionine + CO2 = wybutosine(37) in tRNA(Phe) + S-adenosyl-L-homocysteine + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:37119"/>
            <dbReference type="Rhea" id="RHEA-COMP:11844"/>
            <dbReference type="Rhea" id="RHEA-COMP:11847"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73544"/>
            <dbReference type="ChEBI" id="CHEBI:74275"/>
            <dbReference type="EC" id="2.3.1.231"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + S-adenosyl-L-methionine = 7-[(3S)-(3-amino-3-methoxycarbonyl)propyl]wyosine(37) in tRNA(Phe) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:36903"/>
            <dbReference type="Rhea" id="RHEA-COMP:10379"/>
            <dbReference type="Rhea" id="RHEA-COMP:11844"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73543"/>
            <dbReference type="ChEBI" id="CHEBI:74275"/>
            <dbReference type="EC" id="2.1.1.290"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">tRNA modification; wybutosine-tRNA(Phe) biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the methyltransferase superfamily. LCMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.290" evidence="5"/>
    <dbReference type="EC" id="2.3.1.231" evidence="4"/>
    <dbReference type="EMBL" id="JAAAID010001271">
        <property type="protein sequence ID" value="KAG0010756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MR98"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008175">
        <property type="term" value="F:tRNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031591">
        <property type="term" value="P:wybutosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007213">
        <property type="entry name" value="Ppm1/Ppm2/Tcmp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46529">
        <property type="entry name" value="TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46529:SF1">
        <property type="entry name" value="TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13418">
        <property type="entry name" value="Beta-prop_TYW4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04072">
        <property type="entry name" value="LCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 14" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0819">tRNA processing</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00049250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0010756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="762" mass="86207" checksum="5DF19482C42B0CFB" modified="2023-09-13" version="1">MSMNFEDQATDLAVQGTNTSSITSKRSLERLGYLETCHIPGVTERDSPMMFKYVVPKPSRRSPVINRAYYQRTESIRILIEGWIKECETLGVDECAVISLGCGFDPTYFRLATIRKNKQSRTRLKYIDIDYPTLITERLYMIRNQEKLFELLPEDPSKDDVGEFVSDNYSCLGIDLRKLDHLERGLNTAGIVKGQDRMPILIISEVVLAYLEADESDAVIQFFAGYPEATFILHEQCIPVFDTDREEENLHPFALTMFNHFQKTMTPLKTLRNYRSLEDHRDRFQGCGWSSCDIINMNLFSDMIVMPEEGDHHRVLQLEPFDEYDELYWIGSYYFIAVASTGPGDSSVPTRSPDVLREIGLRSKLQHEEFISNIQLDESCYISLDPLQRLSPPPAIPAIDVVWSEKNPFPGSDFNRKGHTLSILGDTAYIFGGFGLDAIDHQEEQRVFQARSQQTRLGSMVRLNLINGSTETLPLEDNGPAPRMHHSAVTTIDGSAIYMYGGRDGPTKVHNDVWRFTPEGGWDPLWRARINRDGNSSAPPGLFKHTANMMTIAGREMMVVVGGRLQSGEANDQIWAFDLEEGQWGHFHWRHAEQRQAFGGIFSHSSVVIKDEEQQDCLVVLGGIRGSDEKVLNKVWRITLEVNEDESQCRIEAREIDIKARTGNPLKPRFGHSSILVGEDRIWVLGGVSAPALLQWQETMIEIQLSTGIFQHLNPSSFRELVMVGHATAVDKDRNRVIGVGGGGTCFGFGAWWDATAWALQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRG5</accession>
    <name>A0A9P6MRG5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001881</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001442">
        <property type="protein sequence ID" value="KAG0009988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRG5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="40"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0009988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="529" mass="59404" checksum="30257C7D85A2E87C" modified="2023-09-13" version="1">MQKTGPKLSTASVCPKFLANLIPMITIPAKANSPPANSSPCNLMYLPGEIIDFILRKLEPRDLLHLTQVNQTLRYISLLRLEAWFDMRLPARERLLKSHTPELSPMECTPPIGPANDRGEGQAQVEFDLYVKLSLREFNQFQSGRNAAVSADCMVASAMVTAGNLLARLWRPDYSTLKQSTRFGKARRNALNLKNSGMNAANAINSITGSNSNSNSNSSTLSANDEIMRRAEFIVYWIAREVFVTGEMSPETAILVLEFLDEQYPIWGAIHTSHFSKLAESEIDSRIQPDLLLSDSFLFSNFFFRISQQVTEALLNKPCKTDISTTITVTATTITGTSLFKALQVPLPVPKEFKSMTHQVQCMMVWPLRSCQIDQFHCSQIKLFLPNDYCKYSNRHPAGFNSVLFDILQGGFLKASLTNFFFTRYDRTSPKTTKCSEPTTGEHAPMLCTESATSIKDLFEIPESKDISACLGRYWDLRQESDRILDAIIKGPEVNNAQMLSAMQTFTGVLSFTGKSSRITRPRKRVRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRL7</accession>
    <name>A0A9P6MRL7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">PtdIns(3,5)P(2) sythesis regulation factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">VAC14</name>
        <name evidence="7" type="ORF">BGZ80_000840</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VAC14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001186">
        <property type="protein sequence ID" value="KAG0011218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRL7"/>
    <dbReference type="OrthoDB" id="5574975at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070772">
        <property type="term" value="C:PAS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006661">
        <property type="term" value="P:phosphatidylinositol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026825">
        <property type="entry name" value="Vac14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021841">
        <property type="entry name" value="VAC14_Fig4p-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16023:SF0">
        <property type="entry name" value="PROTEIN VAC14 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16023">
        <property type="entry name" value="TAX1 BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12755">
        <property type="entry name" value="Vac14_Fab1_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11916">
        <property type="entry name" value="Vac14_Fig4_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Vacuolar protein 14 C-terminal Fig4-binding" evidence="6">
        <location>
            <begin position="612"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="429"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="804"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="876"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="925"/>
            <end position="1086"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="429"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="448"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="484"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="804"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="883"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="928"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="961"/>
            <end position="972"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="989"/>
            <end position="1011"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1021"/>
            <end position="1034"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1041"/>
            <end position="1050"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1054"/>
            <end position="1065"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF11916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0011218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1086" mass="120654" checksum="41B7B14F64431F65" modified="2023-09-13" version="1">MSDYILSPQVSRGLSDRLYDKRKGAALEVERVIREYVHAGDTAKIKLTIQALVTDFVYSVSANARNGGLIGLAATSISLAGTVSTYLESIVPPVLMCFSDLDSRVRYYACESMYNIAKVARGSILRYFNELFDAMSKLYADSELSVKNGAELLDRLVKDIVHEQSISYSGPISHIDDQDPQQLALSMPRVSQFSLPRFIPLLAERVYSKNSWTRNYLVTWIAVLDSIPDLELVSYLPDFLDGLLYFLSDPNPDVRTLTQKLLNDFLAEIRDIAELQQQQQHELLQARLKQLQMSDSQQRTRDNADESLALTTTDNAVKNRELDLLEIESTGQGKGSWVPGQGVSINYAKIVKILKPHLTSSDEDIQETALRWINEFMSLAKDVMIQFTPSLIPAVLPSLAHSVNSIRAIANETNLSLYRLVYESALPPESQQAVSHSGAQTSDRSTNPRSQSPRPQSPRQDRSSMSFGTSGSIASKMASGGATKDQTTQPSKENTIDHVASPAASQKLTSDQLEFDYVATVNALTLQFLNEHEQTRVASLEWLLMLHKRAPHLILAIDDGSFPVLLKTLSDPSEEVIKRDLQLLAQISSYSDDAYFYNFMLNMLSLFSTDRRLLEHRGNVIIRQLCVSLNSERIYRTLAEILEKDEDLEFANMMVQNLNIILITAPELADLRKRLKGVDSKDGQALFTVLYRSWCHNPVSAFALCLMAQYYEHAVALLQSFAEFEITVNLLIQVDKLVQLIESPVFTSLRLQLLEPERYPNLYKCLYGLLMLLPQSSSFATLRNRLTSVSSMGFIHLVPKISGGPNSVSTSSSVSGISTRSKAGAGSNTSSHHPEGPKFPELLSHFKAVQGRHERNRRQTVQALLRLNTYGNSSSGLAGTAHYSQQQQYYQQHQQKHQRKQQQQLEHQQLQQQVQQQQQLYDLAHQQASGDQVGSPSRSYQQDGSYAGQTESTSERDHATRGSNNVNNTASGTPRRRTRDRQSQLDILQQQQQQQQQQQQQGQQTSTTSGQRSSFIKGNQSNSNYRSYASSSAGTPPPAQPTTATSSPVAGSSMPGTVSPSSVTAPSGGGSAVSDFTGDSKSSKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRS3</accession>
    <name>A0A9P6MRS3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mediator of RNA polymerase II transcription subunit 20</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Mediator complex subunit 20</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">MED20</name>
        <name evidence="6" type="ORF">BGZ80_001625</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the Mediator complex subunit 20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001376">
        <property type="protein sequence ID" value="KAG0010270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRS3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013921">
        <property type="entry name" value="Mediator_Med20"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12465:SF0">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12465">
        <property type="entry name" value="UBIQUITIN SPECIFIC PROTEASE HOMOLOG 49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08612">
        <property type="entry name" value="Med20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0010">Activator</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="122"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="185"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="122"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="139"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="185"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="197"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0010270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="343" mass="35082" checksum="5DC6594EA3E26FA8" modified="2023-09-13" version="1">MGATCLVHWKDANGQQSLTLLSDRLLKQFHANSIGRWTINWKVFRDTSPVSKSGTGKMLHLVHVQGGATASGIPAGSQAANLSSGGILTGSNVVTGGTGPGGVSGIATSGGMGSSGMAGGSGMNAGVGPGKPGLSILPSGGGPAGSGAAGGGIGGPGAPGSAQIADAYNSTAWCLIDDGAVGAPPSSATSTVPSAVNTPMSSAGTENATNPKKKAVLVEVEKDIEALLAKLKNLWVQRQHAQVEGYVFDLGDFIVRAGNIMVASTSYKGMLIEIEYLPQTSNATASNAILEEFVQLISPPGVTLYSPQMLDYPYEQVGLDPKNWSMLHSGFQYMVLFRRQHIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MS76</accession>
    <name>A0A9P6MS76_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_000780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001170">
        <property type="protein sequence ID" value="KAG0011317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MS76"/>
    <dbReference type="OrthoDB" id="411524at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="13"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0011317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="146" mass="15845" checksum="036473694972E43B" modified="2023-09-13" version="1" fragment="single">MAVAVSGNLCTCLLRYVVLAFLAFSVLYTSGSLVFPNLSSEDLRKNAAGLIQRGAGAAGVSAGSLSWIDNQSPTFEIESIKYSKQKIAVQPVNNKGANKDSVDEDFFLSKVYSTAMQPSKVIPYYFRAEGVFDKEEVTITTLITEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSF5</accession>
    <name>A0A9P6MSF5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">cytochrome-b5 reductase</fullName>
            <ecNumber evidence="4">1.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_000595</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion outer membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.6.2.2" evidence="4"/>
    <dbReference type="EMBL" id="JAAAID010001125">
        <property type="protein sequence ID" value="KAG0011559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSF5"/>
    <dbReference type="OrthoDB" id="432685at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090524">
        <property type="term" value="F:cytochrome-b5 reductase activity, acting on NADH"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06183">
        <property type="entry name" value="cyt_b5_reduct_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001834">
        <property type="entry name" value="CBR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370:SF171">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00406">
        <property type="entry name" value="CYTB5RDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0274">FAD</keyword>
    <keyword evidence="5 8" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="10">
        <location>
            <begin position="105"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="41"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="308"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="318"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601834-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0011559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="374" mass="41377" checksum="DC8D4C28728A1A0E" modified="2023-09-13" version="1">MFRPSIISTCSVRARAAASIPSPLIPSSRLRPNAPLRFYSRSPPKAAFNKPKPGETSARAPRASTATNVVTFLAVSSLSVGAYLYQWNKNRQDSSSLNSEGLTTEKWTPVLLTKITKVSEHTSLFDFQLSKPCTIPISSAIYVKDDLIQAMRAYTPVHSTEKDQQTFQLLIKRYNEGQVSRFMHSAKPGQKIEMRGPVVIWPGGRSDLEQWDEIGMIAGGTGITGLLPIIHSALTHPTKKIKISLLFAAQSPDELYFKDEIDQLAKTFKDQLRVAYTIDKVPSTDPSEWKGYVGYVNQDMLKELLPAPKAIKDSSSTEEEKDKSEAKKSIVLVCGPESMIRHVAGSRGMSGQEPIRGVLGAMGYKIDQVFRFPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSV9</accession>
    <name>A0A9P6MSV9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">arginine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Arginyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">RARS2_1</name>
        <name evidence="13" type="ORF">BGZ80_000561</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>tRNA(Arg) + L-arginine + ATP = L-arginyl-tRNA(Arg) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:20301"/>
            <dbReference type="Rhea" id="RHEA-COMP:9658"/>
            <dbReference type="Rhea" id="RHEA-COMP:9673"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78513"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.19"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.19" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010001118">
        <property type="protein sequence ID" value="KAG0011599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSV9"/>
    <dbReference type="OrthoDB" id="68056at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004814">
        <property type="term" value="F:arginine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006420">
        <property type="term" value="P:arginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07956">
        <property type="entry name" value="Anticodon_Ia_Arg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.730.10:FF:000006">
        <property type="entry name" value="Arginyl-tRNA synthetase 2, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000058">
        <property type="entry name" value="Mitochondrial arginyl-tRNA synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.70">
        <property type="entry name" value="Arginyl tRNA synthetase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001278">
        <property type="entry name" value="Arg-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036695">
        <property type="entry name" value="Arg-tRNA-synth_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035684">
        <property type="entry name" value="ArgRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008909">
        <property type="entry name" value="DALR_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00456">
        <property type="entry name" value="argS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11956:SF11">
        <property type="entry name" value="ARGININE--TRNA LIGASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11956">
        <property type="entry name" value="ARGINYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05746">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00750">
        <property type="entry name" value="tRNA-synt_1d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01038">
        <property type="entry name" value="TRNASYNTHARG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00836">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DALR anticodon binding" evidence="12">
        <location>
            <begin position="551"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="480"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="491"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00033033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0011599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="670" mass="74310" checksum="35B23210161F6D5B" modified="2023-09-13" version="1">MASTRFKNVIAGQLAKLTGGDASAIVKAIDRPRVKGHGTFAVPLPRLFPSASVQKNKVPGGPGGKGKEKRTEDHGLQDAMAALLARIHNEASEDETMDLQSICEFDTTGLIRSVTPTGQFLNFGVDERQYIHETIQDVVKAEHAKSQLLSQSSSSSVSGPLRVASLGYGMDPSVGKSQVVAIDYSSPNIAKPFHGGHLRGTILGNFATRLLTGFGYQVVGINYLGDWGKQYGLMAVGFDRYGDRSQLHRDPIKHLYDVYVKINREITEDPSLDKLANQYFKQMEDNDPTVLSLWQEFRSLSIEVYKVMYKRLGIEFDVYSGESESAKYVPQAYELLRSKGLLKDQEDGSLVVDLTEHGLGVCTLRRADGTTLYLTRDVAACLERVERFKFDRHLYMIGDDQNLHMQRLFKIIELAFAEEAASASNSSSSLPHWSRALQHISFGKVQGMSTRKGSAVFLEDILDTAQSTMLEKMKENESKFEAVKESIQQQDRQDESEGNRKENEEAGIAKVADQLGISAVVIQDFQARSSKGYEFSWKRMTESTGNTGVYLQYAHARLCGIESKSGIRLNPSANTDLLTEPEAFELANYISMYPEITLQTLQTLEPSMIVNHLFGLSHAISSANQVLQVKPAAESGRQDLAEARMLLLWAARVTLGNGMRILGLEPLERM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSX7</accession>
    <name>A0A9P6MSX7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_011705</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000976">
        <property type="protein sequence ID" value="KAG0012486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSX7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050995">
        <property type="entry name" value="WD-F-box_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14604:SF4">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14604">
        <property type="entry name" value="WD40 REPEAT PF20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="F-box" evidence="5">
        <location>
            <begin position="86"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="194"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="234"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="274"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="314"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="354"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="394"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="464"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="7"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="464"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="554"/>
            <end position="570"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0012486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="603" mass="66733" checksum="CCA8F2BA34A0AB80" modified="2023-09-13" version="1">MHTGRRQSSIQLQSTSASSSDDMPLHQLNSLTVSTETFDSANSSFNSGPINITDSVAGQPTTPVVTHLDQPRLEDQFYSLLDGSRIDILSKLPYEITNYILLFLDMTSLAKVAIVSKAWNQFANDNEVWKSVYLYHQQWKIRTPNQAQALKDNNSSCPLDNSQRTVTTLDWKRLCRDRKTLEARWRSIPAKTKLIGHEDSVYCIQFDNTKIVTGSRDRTIKFWDFHTLQCTDTLEGHTQSVLCLQFNEKKMVSGSSDNTIIVWDMETHKPISRLYGHTAGVLDVCFDDQYIISCSKDTSIKVWDVHTMTLLRTMTGHRGPVNAVQLHGGQVVSASGDGLVKLWDVATGACIRDFIGHERGLACVQFDGETVVSGSNDKTIRIWEASTGNCVRVLKGHDNLVRTLHFDRNRIVSGSYDYTVKVWDMATGECTLDLDNGHVSWNMSTVETKVETIQVEDGTVAATMTKSSTSSQSASVEAQISELSISDDATRSISDNESESDGDKKSKKEKKKGKEKTTILDDLSSDDESDEDYKPSSSDESESDDSSSSSSSDSESDEDSDKDVDNEEVETLAKEAAEIGAGLDVDNKVLRTGKVVDSPATSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MT16</accession>
    <name>A0A9P6MT16_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">RED-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_011755</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RED family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000987">
        <property type="protein sequence ID" value="KAG0012414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MT16"/>
    <dbReference type="OrthoDB" id="3366823at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039896">
        <property type="entry name" value="Red-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012492">
        <property type="entry name" value="RED_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012916">
        <property type="entry name" value="RED_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12765">
        <property type="entry name" value="RED PROTEIN IK FACTOR CYTOKINE IK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07807">
        <property type="entry name" value="RED_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07808">
        <property type="entry name" value="RED_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="RED-like N-terminal" evidence="7">
        <location>
            <begin position="84"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="domain" description="Protein RED C-terminal" evidence="6">
        <location>
            <begin position="549"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="373"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="545"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="602"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="41"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="80"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="103"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="413"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="476"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="502"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="611"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="659"/>
            <end position="671"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0012414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="679" mass="74638" checksum="0FF44C0F47B8D03C" modified="2023-09-13" version="1">MSNPMPPPEFKPPPEKKEEKTGLSQDDFRKLLATPRAAPGGASGISGSFSGGGMRALGMANRTTRIPVPQTPRSSEGSGGHKHKHKKFSQKNPAKEASAAGSKYRDRATERRQGINPDYIETEQILHTLEEAAADVAPEVLYEQSKFLGGDREHTHLVKGLDYALLNKVRQEDAEHGSESADLDEVFESVEMTTKSETESKVKSEQVQEAPEATSAMARNVFKYAIEEPAKKLPKVNEMFLPGRTVFVFEVPITSKSKRSKTGVVEDNNPFAVPTTVVRSRADVDQNKAGIVENPEADMVMKKVMDVLQAIRTGERRIGESEVELKAKRKAAAAAAEKAAAAKLMDEEVLPMVEPDLDGDDIFADAGREYVVEPTHQSESVAENVMDVDGDEQGPMVGPARPDDVDMSHYFSDESENDQEQDDEEEDNDGSGDKQLSGQTSTLDDEAPVLGPSRPSEVDMSNYFEEDSEEEGSQGSEHDGVDGDGYHDDVSYPKSGTAGPSIASSELTTPINENALPRRKPRLEDLEIDEDADYYSAYGLGMGGGLGTTAYDSDDDDDQTQSTILIDKGTHKNKRAQLGRFDFDTEEGFNRYKDTVEVVPKTSFQYGVKMSEGRKTGKWEDSKGKGLSKDEKLDRDWQRISRLMEKNSGSGNSQKPKSRRDDGSSEGGDNRSKRRKNNW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MT73</accession>
    <name>A0A9P6MT73_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_011701</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000975">
        <property type="protein sequence ID" value="KAG0012493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MT73"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0012493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="658" mass="72832" checksum="087AC45CEC17423B" modified="2023-09-13" version="1">MNTLVDSTKTAADKNSFGSLDVDVILKPALGGTITPPFDASGPATAPAPAPAPSHKPRGGSITPGGSISKSELSTMTGSIASKLDQYLGNTSPTGGLSRANRSSIDSTASDLISATALSNQGGNGSSSEVDEDTALANNLAAISLAAQKISDIYLEPKPKRATQDGHQVTNEHFEPEKHFYPRVLNAQIHPMVGYFFSLGNERIIARYMHLNPQVSEEHLRRCLEYVPKHFQWAGKRFVASVPIADCSDLFNVTTASGHRQMIIVETNSCPSGQKSMPLLSESDEHGGYRLVLESAFKDIIDNADLSLGDLAVVCDKNMMESSGYAATLAEVMKEKVWLVEYYEHDQDPPVKWVDRVMYIRDEKKEWHSIRACFRYVTQKPWNRFPLYTKTVVMNQTVACLAGGRNKMMAAKAYELFNAELADSGLYVRVPETINNVTKNEIPLWLDSMGGHAVVKVPYSNAGQGVYTITNKQELQDFMDTPQHYDKYIVQSLVGNASWSSITRHGKFYHVGTIPNKRNNTFVTDLRMMVAGNKQGFRPICIYARRARKPLIRHLEDDPSTTSWEMLGTNLSVKSPSGEWSTEAARLLLMDRKDFNQLGLGVDDMIDAYIQTVLSVIAIDKMCQRLMKDNTDGPGQTFDLELFKALNPDSVLWQEVVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTN3</accession>
    <name>A0A9P6MTN3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Cytochrome b5 heme-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BGZ80_011267</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the cytochrome b5 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the fatty acid desaturase type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000887">
        <property type="protein sequence ID" value="KAG0013137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTN3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004768">
        <property type="term" value="F:stearoyl-CoA 9-desaturase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006636">
        <property type="term" value="P:unsaturated fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015876">
        <property type="entry name" value="Acyl-CoA_DS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018506">
        <property type="entry name" value="Cyt_B5_heme-BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11351">
        <property type="entry name" value="ACYL-COA DESATURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11351:SF31">
        <property type="entry name" value="DESATURASE 1, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00075">
        <property type="entry name" value="FACDDSATRASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00191">
        <property type="entry name" value="CYTOCHROME_B5_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="4 14" id="KW-0349">Heme</keyword>
    <keyword evidence="10 14" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="15">
        <location>
            <begin position="153"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU362121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0013137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="257" mass="29081" checksum="40322A51CA5596BD" modified="2023-09-13" version="1">MLIKRPGWKIGHADVDDLNKSKLVRWQHKNYIPLVLFMGIIFPTLVAGLGWGDWRGGFYFAAVTRLVFVHHATFCVNSLAHWLGDGPFDDRHTPRDHFITAFWLIAACAFFGLASHLKTFPENEVRKGQLQMIEKKVLEKKTKLQWGTPISELPILSFEDFQHACKNDNKKWILLEGVVYDVADFITEHPGGPKYLNMAIGKDMTTAFNGGMYDHSNAARNLLSLMRVAVVEFGGEVEAQKKNPSVPVYGDDHIKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTU2</accession>
    <name>A0A9P6MTU2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_011467</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000924">
        <property type="protein sequence ID" value="KAG0012862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTU2"/>
    <dbReference type="OrthoDB" id="3936150at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF5">
        <property type="entry name" value="QUINIDINE RESISTANCE PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="30"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="98"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="121"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="156"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="401"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="437"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="512"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="537"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="574"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="607"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="32"/>
            <end position="629"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0012862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="643" mass="69904" checksum="B6A9B166A9BAB806" modified="2023-09-13" version="1">MSSAMSYVKGLFVTEPKTDDPKNWTNKQKYIVVTVIAYCAFVSPLASSIYMPAIVQVRDDLNTTSSMVSATLSVYVLILGIMPVFWASLCDYLGRRPIYIASMTIFIIGSFLAAISKNIWVFFFMRAIQAFGSSSVLSVGGGSLSDIFHSGERGSAFGLYYLGPLIAPMIGPILGGVLSDRAGWRSTMWLLFGAAVVALFLVIFILPETYRRHIDESPAPEKETAVDASHVSRSHIYSTHSTLVASKTSLHSTSSRRSAVGVPLSIPSDRMSIHSAHSAHTHHSVVNQTESAMEFIVPNFVPPYMMQDDEDEANNAEGSGNSSIMKAGIQKTETRHVAFPTEKQELEQNEKQADAKSAVSVAIAQEAMTDGNNEGQDEIDESLKRKPFNPLRPLLCLRKPTNALLVTFNALALGSQFCMNNTLPISFTNNYNLSESIIGVCFCAGGFGSVTGSLIGGRYSDFVMRRWLIKQELKRQRDEKDRQAAFGENSTAASEINIDLSMRAPPEVRLQSVWLGVFVLPIGLMLFGWSVQKDLPLPVPLVAIFLVGFGMMMVFSSTTTALVDANSDNNMATAAVACNSFARGVTGAIGGFTALPLEAVMGSGWLYTFWAFMTLIGAGGLVLMVVKAKSWRERAAAKALDKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTV1</accession>
    <name>A0A9P6MTV1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">COPII coat Sec23p-Sfb3p heterodimer component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">SFB3_4</name>
        <name evidence="2" type="ORF">BGZ80_011660</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000966">
        <property type="protein sequence ID" value="KAG0012562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTV1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030127">
        <property type="term" value="C:COPII vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070971">
        <property type="term" value="C:endoplasmic reticulum exit site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090110">
        <property type="term" value="P:COPII-coated vesicle cargo loading"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007123">
        <property type="entry name" value="Gelsolin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036180">
        <property type="entry name" value="Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050550">
        <property type="entry name" value="SEC23_SEC24_subfamily"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13803">
        <property type="entry name" value="SEC24-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13803:SF4">
        <property type="entry name" value="SECRETORY 24CD, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00626">
        <property type="entry name" value="Gelsolin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82754">
        <property type="entry name" value="C-terminal, gelsolin-like domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gelsolin-like" evidence="1">
        <location>
            <begin position="64"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0012562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="206" mass="23968" checksum="B39D518318E62EF0" modified="2023-09-13" version="1">MLKSNTLRPGKGINSDTRVYHMRMIKSMGVGESIVFYYPRMIAVHNMNEKVGVMDPKSGRVFLPSLVRDSYARLNPTGAYLLENGHKMYFWLGHEIPAQFLLDVFGVQTLDEVNPNQRHLPELDTMTSSQLRMIRTYMQAQRGRYLDLVIIRQGKDQPEHEMSNLLVEDKNNEAMSYVDYLPTIHRMIQTEVTTRPHEVHTSIWSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MU04</accession>
    <name>A0A9P6MU04_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_011519</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000935">
        <property type="protein sequence ID" value="KAG0012781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MU04"/>
    <dbReference type="OrthoDB" id="5562028at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0012781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="85" mass="8820" checksum="33F7EC911DBB310D" modified="2023-09-13" version="1">MTSVIKAGSDIHSEQLDGALRSSASSAVNSVKAPSVREVLAEKTIDSKTLGWMASAMGELHQATEQIDVEDVGDLIVTLSPPSGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MU90</accession>
    <name>A0A9P6MU90_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HCP-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_011171</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000868">
        <property type="protein sequence ID" value="KAG0013288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MU90"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052748">
        <property type="entry name" value="ISR_Activator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45011:SF1">
        <property type="entry name" value="DAP3-BINDING CELL DEATH ENHANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0013288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="558" mass="61122" checksum="A4F8F16147598E14" modified="2023-09-13" version="1">MSDTKQNPLPQFQYISLDGTMRTSSSLAGPMFINNQLESTCFNAKTAHNNNTLYPPVDVGPSTRNATSPTTGAISQNGRYDFAPSFHQESLDNSTTSVSKPSCSDSTIRNDDLYSATQTELIEGGVILGNGPMDVEHHNGTNAEDEYKLGIAYLEGDGVAQAYFKALGHLLKAANQGHVKAHTKIGYMYSHGEGVPKDYSRAVEWYRIAANQGSSKSQCDLALMYLEGCGVTQDYVKAAEWFQKSATQGNAVAQNTLGNLYRTGKGVTRDRFKAAELYQQSANQGLAAAQSNLGLMYKKGYGVKRSYGKAFEWVLRGASQGNAIAQGNLGTMYQGGCGVPPNLLEAAEWHQKASDQGYVRAQFNLGAMYESDCGLNQDYAKAVELYEKAATQGYARAQYNLGQLYQDGKGVTQDYSKAAEWYEKAVYQGNVKAQGKLGFMYENGYGVDRDYSKAVRLYQNAASQRDLTGQYGLACMYRNGRGVARNYLKALELYRSAGTAGHVMARHELGVMYFKGEGVPMDMCIAMKWWERATDERFATHNVNLSQGTSMTSSRGVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUK3</accession>
    <name>A0A9P6MUK3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Spc7 kinetochore protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_010651</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000764">
        <property type="protein sequence ID" value="KAG0014103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990758">
        <property type="term" value="P:mitotic sister chromatid biorientation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007094">
        <property type="term" value="P:mitotic spindle assembly checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034501">
        <property type="term" value="P:protein localization to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040850">
        <property type="entry name" value="Knl1_RWD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033338">
        <property type="entry name" value="Spc105/Spc7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013253">
        <property type="entry name" value="Spc7_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28260">
        <property type="entry name" value="SPINDLE POLE BODY COMPONENT SPC105"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28260:SF1">
        <property type="entry name" value="SPINDLE POLE BODY COMPONENT SPC105"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18210">
        <property type="entry name" value="Knl1_RWD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08317">
        <property type="entry name" value="Spc7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00787">
        <property type="entry name" value="Spc7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Spc7 kinetochore protein" evidence="2">
        <location>
            <begin position="750"/>
            <end position="1079"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="188"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="403"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="526"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="694"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="734"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1229"/>
            <end position="1260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="33"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="260"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="290"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="538"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="566"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="595"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="697"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="740"/>
            <end position="749"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0014103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1332" mass="147527" checksum="770E572CDBB82E7E" modified="2023-09-13" version="1">MDEDNVQQGHQQDQSQTDINATPVTELESGTMQEEQAQESQNEATSSKRALPEDETHQEDSMSTPPSTQSSTESSTQPLPSQENAPQLPGKSILKSANQDDDMDLTGTQDTFEDPVSGNGSTNASDITETFSSTTEFLKRSRKSIGRRVSFAATARIRMFERDDKDDELPKTMSFLEGLNPKIALSTPFLFESGNSGGEQVNNDSDTNDTKDTNGANDTNDSMASVRTGQSFQAQAENTEVSTGSSDSEKERSFEVNVYSGHSDSTGSSGSGTPFFLPSSDLDIGKTPFDDGDVDNGSSSEDESNFFPDANLMKRSSGVGLYQEDQDSILGPRIDLAQAGDSRLPQRSENLDDGTQDYSMEFRFLKHRSSIPERLPTPPPQQYDGDQEFTHDFLDSQQYDADQTDPLSKGLPVSASGGDISNDHSDVGKPIPLVAHNDLSINILSIGNDVDLSIAEALSKDDRSILDEDTDMDITAPIGMGIQQISQELPPTAFHHAEDHTALFSDLGTPMDITQPFGAGILEANDESAAAESAPRTGASQYASLPSTSIRPTGDSTVLNNSNDMTAEHQTQDTGDYSRADQSQSEQAAAPSTPPRRSSYPRRSLGTPGRFTPSVKARPNIFPEVLEKQLQTLESTVHTEPVFRASHVSPETSSLAKRIYRYSVGVSSRRASNFENKLEEDRDDTMDLTSLEKRRSSTQNFGNDIFNDNQSHADEDMTDVIGNDDRTEEIYQNDAAEAAPESHEKAHDEGGDDDSFTELPPITLSKFLSLVGISFLDHLNASTRRRTIPHRANEADASTATYRSADLVKAMAVSMQELHSYREACRLLKQSIDTSRAFADEQEKKVSKKNPEYFNEFRESNSDTKDFMKDRFKMIKVHSKLETNAAFSSWKTDVLKVEQETLERHLVELKKDIANLGSIASTLVKEKARVLPRRDKLKRQLDQATERQRSYELCDKEQLASLAEAAEEQGAQIEHYESIKAKKAKELAEIRARVEQLSLVEKATKGRISEAEKTIQKHQYVRTEDLSRAKDILSIIQATHRWEPLRSSASASNSLTTTPQRGDKPLEFVYDKTLKVSIDVAKIGKDPSAVQLSEFEEENMMDFDLSLVDRQRLTISALAPKKRKPVKEYLGLLHDYMTMVAAKYKAGTTISKILNDISQFCTKVNLIRREVELIRAHHVVDLVAGSAENLKELELNNSDKNSKSVAGSTTPLVVLDIRVRFTGPIMGTRRSTRQRNQGDEEMEDVDGIEGHRNGRSKGASGTEPVKFYLWFTFTLNDILNFPGSSSFTWRLEIVYGNISDEYVTQAIGPAVKKGGYDVLREACIKVNQLLKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUK6</accession>
    <name>A0A9P6MUK6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Splicing factor YJU2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_011354</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA. Plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the spliceosome. Present in the activated B complex, the catalytically activated B* complex which catalyzes the branching, the catalytic step 1 C complex catalyzing the exon ligation, and the postcatalytic P complex containing the ligated exons (mRNA) and the excised lariat intron.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the CWC16 family. YJU2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000901">
        <property type="protein sequence ID" value="KAG0013034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUK6"/>
    <dbReference type="OrthoDB" id="674963at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071006">
        <property type="term" value="C:U2-type catalytic step 1 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000349">
        <property type="term" value="P:generation of catalytic spliceosome for first transesterification step"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03226">
        <property type="entry name" value="YJU2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007590">
        <property type="entry name" value="Saf4/Yju2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043701">
        <property type="entry name" value="Yju2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12111">
        <property type="entry name" value="SPLICING FACTOR YJU2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12111:SF1">
        <property type="entry name" value="SPLICING FACTOR YJU2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04502">
        <property type="entry name" value="Saf4_Yju2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="5 8" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="100"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="244"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="108"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="271"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0013034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="326" mass="36404" checksum="36B7D00AD7BA2B36" modified="2023-09-13" version="1">MSERKVLNKYFPPDFDPALIPRRKQPKDLQHKVRLMTPFSMRCNTCGEYIYKGKKFNARKETTDETYYNIKIFRFYIRCNRCAAEITFKTDPANSDYVAENGAQRNFEPWRDESGDKNAEREEEEENNPMKALENRTQDSKREMEIMDALDEIRTRNALNERVDADVLLNKLAGSGEEIALRKQQEEDEEDERLAKAVFKNTDGERVKRLLDDQDGQEEVNAVQIAMSKFSQPLVMPDFSAPVAKKSKQQGGLQGLVRISGSASTSKPDTLKPASTSTTSATSATSTASASKSTSSSATATSTPTSKPSLLSLVGSYGSDSESDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUN0</accession>
    <name>A0A9P6MUN0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">GTP-binding protein Rho1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">RHO1_2</name>
        <name evidence="10" type="ORF">BGZ80_010549</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the small GTPase superfamily. Rho family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000745">
        <property type="protein sequence ID" value="KAG0014262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUN0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000329">
        <property type="entry name" value="GTP-binding protein rhoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003578">
        <property type="entry name" value="Small_GTPase_Rho"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24072">
        <property type="entry name" value="RHO FAMILY GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0488">Methylation</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0636">Prenylation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0014262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="195" mass="21988" checksum="2725D6915665EAA8" modified="2023-09-13" version="1">MSDIRRKLVIVGDGACGKTCLLVVFSIGEFPEIHVPTVFENYVTDVHVDGKAVELALWDTAGQEDYDRLRPLSFPDAHVILICFAIDSPDSLENVEEKWHPEVQHYCRGLPFILVACKKDLRYDQRTVDELRRNNQTPVSQERGAEVARRIKARDYVECSAKTKEGVDEVFQKATRAALLVGASSRRANKTCLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUQ0</accession>
    <name>A0A9P6MUQ0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">acetate--CoA ligase</fullName>
            <ecNumber evidence="1">6.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ACS1_3</name>
        <name evidence="7" type="ORF">BGZ80_011404</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.1" evidence="1"/>
    <dbReference type="EMBL" id="JAAAID010000912">
        <property type="protein sequence ID" value="KAG0012944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUQ0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003987">
        <property type="term" value="F:acetate-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006085">
        <property type="term" value="P:acetyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.30:FF:000004">
        <property type="entry name" value="Acetyl-coenzyme A synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24095">
        <property type="entry name" value="ACETYL-COENZYME A SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24095:SF14">
        <property type="entry name" value="ACETYL-COENZYME A SYNTHETASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="5">
        <location>
            <begin position="8"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="6">
        <location>
            <begin position="202"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0012944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="320" mass="35183" checksum="656D5805E53DDB2B" modified="2023-09-13" version="1" fragment="single">SIPTYPTASRYWEMVAKHKITQFYTAPTAIRALRRLGDQWVEGHDLSSLRVLGTVGEPINPEAWHWYNDKVGKGRCAVVDTYWQTETGSHVVTPLPGAIPTKAGSATLPFFGIDLAILDSVTGKEMVGNDVTGVLAIRRPWPSIARTIFGDHQRFLETYLKPYHGFYFTGDGATRDKDGYIWIRGRVDDVINVSGHRLSTAEIESALIMHHSVAETAVIGANDDVTGQCIHAFVCLKPGFSAISTDLSKELVLQVRRVIGPFAAPKKVYLVEDLPKTRSGKIMRRILRKIVAGEIDTLGDISTLADPSVVESLINKVASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXA3</accession>
    <name>A0A9P6MXA3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_008403</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000454">
        <property type="protein sequence ID" value="KAG0017323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXA3"/>
    <dbReference type="OrthoDB" id="2407620at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0017323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="726" mass="83157" checksum="66B69BCD47CCAE2F" modified="2023-09-13" version="1">MCNVLFISKSNSHISPTSNPSDCGSAVGAQSTAAASAATQIPEVLWEIFSYLSHFDLRYSVSGVNRLWYSISSDLIQDEIHWKDTFTLQEQDMCLARMGSIQVKTLHCLAQDRRTYLAFHQGIEQDVDDAWKKLSQTISALAERKNEFRGRSGSDHATKIATTDGGHKLLPWKRIVYSGWNYFNDRIDPLIRQHCESFHGVRLLHLKHLSPGAVDLSCVFSSLLYLEELVIESSESFPFTFRRNCTITWKERNDQIEKKHGVNHQQQPPLRLHTFKLRHLIVNQDTLEMLIGAFPNLHTLDLKFMISNARKPEIASIDRSSLVDFLAQQCPNLTHFHFSISGTRILTGDIQKVHVSFPNLSSLSIPERDVVPGSLDLFVDRLTSLEIECFEYGHDPWLGDMLHTYMCQAPLLLHLKAYRTRIHQEHFILQLSESAASDPFRYVNPQDAFDQPIWACRNLKTLYLLVGSQHHVTSIQETATSRRVFGYISRVCPNLEDLAIERTILHTEIKSGLSLLSRCKKLRRLRTYTNLQLDPSERDLDWICLGMTGFNSINHERRKRESIFEGIAGALCGNQNTIPRIGRIAEALFGRQNTESGIGGVSKSEREMWVDSTIQSLKKTLLQDHPATDSISRLEEMSRKKESEGLDPIEMTTLDGMEHLICNLQILLQQSIMTSRNENRFCCWPNLETFEMHQMASWATPAVACQDMIYKLRPDLRQYRGLRREI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXG2</accession>
    <name>A0A9P6MXG2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_008502</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000462">
        <property type="protein sequence ID" value="KAG0017244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXG2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24413">
        <property type="entry name" value="SPECKLE-TYPE POZ PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="2">
        <location>
            <begin position="68"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0017244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="280" mass="31366" checksum="9F6BE5B91CA53FE8" modified="2023-09-13" version="1">MLRDSSTYDVFFEFETPVALYDCEPIQGEEKGFVEIKKEEASEPNVKSEKGEETKENALSSPVITSEEDETVETSATTIWDKVGAHKIVLSQFDYFKTMFSSSFAEGGPGVKTIKIRDTDIQCFRLLIEYLYLGRLGLFSVPRTLTEDDAKDSLPTWEDVYLIADRYNVVDLRRMAASHILLGLSTAWALPFLFRTAYLFDDLRSPVIAFVVQSSMDEIVGKDALAKYYDHPECGSIMADLLAALWKFKAAQPSLTPIASPTRKVTVASRGVPHPPRLPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXS2</accession>
    <name>A0A9P6MXS2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RWD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_008842</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the WD repeat WDR59 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000494">
        <property type="protein sequence ID" value="KAG0016868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXS2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035859">
        <property type="term" value="C:Seh1-associated complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035591">
        <property type="term" value="F:signaling adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034198">
        <property type="term" value="P:cellular response to amino acid starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904263">
        <property type="term" value="P:positive regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006575">
        <property type="entry name" value="RWD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049567">
        <property type="entry name" value="WDR59-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46170">
        <property type="entry name" value="GATOR COMPLEX PROTEIN WDR59"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46170:SF1">
        <property type="entry name" value="GATOR COMPLEX PROTEIN WDR59"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00591">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50908">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="217"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="304"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="domain" description="RWD" evidence="6">
        <location>
            <begin position="551"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="662"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1056"/>
            <end position="1085"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="11"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="53"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="66"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="85"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="683"/>
            <end position="692"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0016868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1182" mass="131115" checksum="3C2D42922C1625C2" modified="2023-09-13" version="1">MTSPIPQLPLEMDRNGNRSRSMESNDVNNEGVDTDGTMEVSDTPLLDKDDNKQANSGYANGTNIKQSEDSTKESRQVGPKPLPRLSTSLGSQFNINDNPSTSIIPRAPTFHNGVGPSFVDTMTQQLSIHVEQPVGSMSISPSSRDVVLAARKGLFIIDLENPYEQPRVLHHLTKWEVADVQWNPHFSRENWIASTSNQKALIWNLGHNVPRAVELILHAHSRAITDINWSPFHPDLLATCSVDTFVHVWDLRTPKKPVNSFCAWTAAATVVKFNRMDEFLLASAHDTNLEVWDTRKGSSPFKTIPAHKQKINGIDWSRKHRNHIVTCSLDKSIKFWDIDDPSQPHNEIVTKSPVWRARHTPFGHGILTMPQRTETALSLWNRERPSEPVCKFEGHTDTVKEFVWRVRDAGDTADHRLFQLVTWSKDQHLRLWPISEKMLEAMDHKATSVDITPYPPMYENMSFRDPPPQYMAATPSRALSTLRVLAGNRLSTMTPFRTSMSSRSIGPLESGGLFREQKAPSPLVWMQGVRMAKPSGDLGVPDRASPQTVATEIAAVGQKFPNVKFEKVNIAGRTCTISLNSLRSNEGVSFVRVNISFPQFYPKEAPPTFEIQKSGMLSMATRAQISSNLEHIASRHASRGLPCLEAVIRCLLGEDKRDEVLDKGLDDSDEDDTIVNPLRKSRGRDGGAGDKKDHQVPFPCLCGAVFATNGKLVTFFSKLRTPHATSSTIPVAGRSSTLIKTPYTYTHPRTYSSMGEYKAFSRLPSGADGLAGTVSSIVTDADDQDDLWPMPNLFSKAKPKQELVRVTRKPKDQPAFFKPQPQSRSTLYLKDITHLLPVSPRLAAVYTLNGDSVSEICEHNALQARHLGRLDLYKIWKLAALILTLSVPMDPAAFEMHKSEISRMNSHTHPDKLLDLLNRSSHARQRRDSGLAFIPGLEDTFYHKVKWGNHPLGRMLVDVLFSFLERHGDIQMLALLSCVFKDPFRNALSVTGVALASTTRPINGQSITATPMSVDNSPLRARTPATRISPYLNRVSPTTAALGTSCAPSMKRTSSRLYAGPATSPLATPSSLRDSHMDASSGYGAPNIGPPVAPVVTNAYATQGSLTQEGVAPLPYTHNKRDSFHSMQSTSPTLFSKLGTMHRRESSSSPSSVMDKSERLTVRSNGFKMTKMNSNLFDSEET</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYF3</accession>
    <name>A0A9P6MYF3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Nucleotide-sugar transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_008696</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000480">
        <property type="protein sequence ID" value="KAG0017013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYF3"/>
    <dbReference type="OrthoDB" id="408493at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015165">
        <property type="term" value="F:pyrimidine nucleotide-sugar transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007271">
        <property type="entry name" value="Nuc_sug_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00803">
        <property type="entry name" value="nst"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10231">
        <property type="entry name" value="NUCLEOTIDE-SUGAR TRANSMEMBRANE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04142">
        <property type="entry name" value="Nuc_sug_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="72"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="126"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="203"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="240"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="268"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="292"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="331"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="332"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="343"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0017013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="388" mass="42861" checksum="34804B16C7024BB9" modified="2023-09-13" version="1">MGLISLRRRWCCRSASSACCGNPSQPISQLNNEEEQLPLSGNHINADNDDESEEDDLSKNICSKVSSSSSSLSCGFPPILFFAVPGAIYFFNNNLTFILLSLMPAPTYVVLSNLKILTTGLFSFLFLNRILTTSQWVSLGILFLSTAVSQVDLEKGLSLSISIQAFLLMILFCSLSATASVFSEYVMKERFANESIHLQNMKLYMFGILFNGFTYVVTPPTSEAANDVSSSSFFSDMAPIHYMIIAAYASLGLVTSAIIKFSGSITKVYASSMSMFFAALVSWLFLNDQLTVLFFIGCFGCCIALHLYYRVPAVSPNTPVDREESYEKIMLEEEEEEEEEETQCGSTSSTSSEPRNMPSSSEIDSIKIVGRNGYISLDTHDDHDQRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYJ6</accession>
    <name>A0A9P6MYJ6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Chitin deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">CDA2_7</name>
        <name evidence="6" type="ORF">BGZ80_007695</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000399">
        <property type="protein sequence ID" value="KAG0017970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYJ6"/>
    <dbReference type="OrthoDB" id="407355at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004099">
        <property type="term" value="F:chitin deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009272">
        <property type="term" value="P:fungal-type cell wall biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050248">
        <property type="entry name" value="Polysacc_deacetylase_ArnD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10587:SF133">
        <property type="entry name" value="CHITIN DEACETYLASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10587">
        <property type="entry name" value="GLYCOSYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040429727" evidence="4">
        <location>
            <begin position="22"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="domain" description="NodB homology" evidence="5">
        <location>
            <begin position="100"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="319"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="319"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="329"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0017970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="372" mass="39407" checksum="E2241781AC84F7AB" modified="2023-09-13" version="1">MVKLFATSITVVVLTFAAVKAQVPIVISNYPTINEIPPTDSPQVKAWLAEIGDLSGAPQIPLPNPTGQPPPCAKKPLANECHWTCDGCSADDITACAAPNTWGLTFDDGPSTATPTLLDYLKTQKLSASFFLIGSNVIQYPQTVVRELAEGHHLASHTWSHHALTTLTNEQIVAEMKWTEKAVMDATGLKLKYMRPPYGDINNRVRYVLKKMGYIPVDWTGDQFDTTDWKLPTITEANVISTFTKSLDTYVAGNKTQGFYCLEHDLNKLTVGVAQKLIPLGLAKGIKISSIPVCESDASPYQSGGNATMPTVPGITPTTTSATAVPSGNATAPSSTKTGNNTTVAGKTSAASYQSAGLLTAAAAALVGVVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZG2</accession>
    <name>A0A9P6MZG2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">Altered inheritance of mitochondria protein 24, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_005906</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the AIM24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000291">
        <property type="protein sequence ID" value="KAG0019374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZG2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007007">
        <property type="term" value="P:inner mitochondrial membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.160.10">
        <property type="entry name" value="Mitochondrial biogenesis AIM24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002838">
        <property type="entry name" value="AIM24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036983">
        <property type="entry name" value="AIM24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016031">
        <property type="entry name" value="Trp_RNA-bd_attenuator-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36959">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 24, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36959:SF2">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 24, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01987">
        <property type="entry name" value="AIM24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51219">
        <property type="entry name" value="TRAP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="63"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="78"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0019374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="448" mass="47790" checksum="D707486DF6CF025D" modified="2023-09-13" version="1">MNVRTIVTQVGRRSSHVTSAITIRRAYANLAYNATSQPASGEVPTLDRKLDSLEERIQARREALGNNVNAHTEDNVKDNQAQTESASPSEASKLSKKGIMSILPGINSASKWIKQPSVADPEFEVVSAGLGSMLHVRLPSRSELYAVPGAAVGSSAEVESELSTASNPLKALGRRLAGGSLHFQKFSTSSTAGDVLLAPQYMSDIAAIRMDGTSEYYIRRDAFLARSPRVILQLGLAKAGLGVTNFFAHRVTGRGTLAIASYGGIYRLVLAPNEEYLVNPRHLIAWEAGSSPSASRLAIDPTHQAEPETRSSKILSNPYVASSLNIASRVAERVGNVLFGKQEFVRLQGPGDFYLCSRVRPSTEVLKQVISSTSKLPVVYPAPVAPAPPAPTTPPNTFATVTRDGHVTISKNASPPSTPLTGSIPQIKNQVLGHTEGTTVTKSETSNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZJ9</accession>
    <name>A0A9P6MZJ9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Membrane bound c2 domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_005755</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000283">
        <property type="protein sequence ID" value="KAG0019486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061817">
        <property type="term" value="P:endoplasmic reticulum-plasma membrane tethering"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006869">
        <property type="term" value="P:lipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00030">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd04044">
        <property type="entry name" value="C2A_Tricalbin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21678">
        <property type="entry name" value="SMP_TCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037761">
        <property type="entry name" value="C2A_Tricalbin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031468">
        <property type="entry name" value="SMP_LBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056910">
        <property type="entry name" value="TCB1-3_C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017147">
        <property type="entry name" value="Tricalbin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052455">
        <property type="entry name" value="Tricalbin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46980">
        <property type="entry name" value="TRICALBIN-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46980:SF2">
        <property type="entry name" value="TRICALBIN-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24920">
        <property type="entry name" value="C2_TCB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25669">
        <property type="entry name" value="SMP_MUG190-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037232">
        <property type="entry name" value="Tricalbin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51847">
        <property type="entry name" value="SMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="4" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="119"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="SMP-LTD" evidence="9">
        <location>
            <begin position="168"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="8">
        <location>
            <begin position="366"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="8">
        <location>
            <begin position="638"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="8">
        <location>
            <begin position="818"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="8">
        <location>
            <begin position="948"/>
            <end position="1068"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="8">
        <location>
            <begin position="1164"/>
            <end position="1283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1156"/>
            <end position="1176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="40"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0019486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1308" mass="144189" checksum="173DFF20F76F44BC" modified="2023-09-13" version="1">MPTSTKLDAEKSELPNEQQAQTQANPQSTQVKQPTDKATEATTVVNDNVGKSESKNKTASAFPVITQIGWLEAFKRTDGPQNENRDTSIWMEEFASSALFGAFWRNAAVMFTIPVVCYVFFKFGGGFVSLILIIAFGATYYKNSIRRFKRNARDDIARELIRNTLENNIESTEWINNFLSRFWLIYEPILSASIIQTVDGVLVDSTPSFLDSIRLSEFTLGTKAPRVESIKTYPNSDPDVVLMDWKISFTPTDTEDMTPRQLRTQINPKICLMIRVGKGFIGAGMPILVEDLSLTGEIQIKLRLTSNFPHIKTFEFFFLDIPTIDYVLKPVGGETFGMDIGNIPGMQSFIRDQTHAILGPMMYAPNAYVLDLEQMMSGATLNAAIGIVQFTIYNAKDLKNLELVGNSDPYVKLRLGNRPEIATTQVQEDTLNPVWNETNIILLNSIDEVVCMDIFDKDNVRKDRSLGQASFDLKSLEDDPVQDDVWCKVLRNGKERGSIRIRAAFFPIQKPQPSADGGEPIPVESNSGILTINVAQAKDIVRSSKNKSLCQISLNGKMVHETKKQFGSSPSWWGDTDVFISDLQSAQINVDVISNGQVVGSYGVSATKLLQDTENKVEWASLKGGEGTGKIKMTGVWKPILMDDSLNPSVNKPPFGVLRVQLLAGRDIKNVEIGSNSDPYVIIQGERGISQGRTKTIENNLNPVWNEIHYVSVNSLKQSIDFEVFDYQKMSKDRTLGKTSFKVSEVIEELPDDKWYAARPAVNRWAPLIQKDGSSKGELHYDISFFPSLKVAQEAKEKSSAPAPIQATPGVEGGSAPQTAAVTLPPGTIRAEEVLDHDSGILVINLIEADLARSGTYCEFYVDSDDHQFKSKVQKTRNPKWNEFASIFVKELEYAKLVILIKEKSSMEKDPVVASFTSNIRTLLESTPAEGQSFPLEKTEQRSTIRLRFEYLPIPIELLPKERLDNMGNLTVDLIRAKNLIAVDRGDASDPYVVFKVNGKEVHKSEVIKKTLDPEYNEHFVVPINSRADDQFSLEVFDWNQLSAAKSLGVASIDLKNIQLVLPNDFLIPLQNKRSQGEVQLRLKFIPEFLSSNKAKTGFGSTFLVGGVNMVAHGGQAVGQGALDVTGAVGKGAFKAVGTVGKGVFGGLSAGASAVGLKRSEKPSPHPSSVDVQHPTTTGVSGNLTLHVIEADGLLGVDKSGLSDPYVKVTAGGQNVLKTKVKKETLTPNWNESAFLPVTGQPLMINFLVKDYNTIGGNKDLGDCNISLWDYIQPAAEGRPGQLRADFWAPLSGSGGRLHLVFEFQPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZQ4</accession>
    <name>A0A9P6MZQ4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005523</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000272">
        <property type="protein sequence ID" value="KAG0019629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZQ4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0019629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="159" mass="17258" checksum="767EDEFABA60293D" modified="2023-09-13" version="1">MNTTTMCEQPDTDTPWHQTNQDNTNEYHPCELDLGDGSDPIREGHFDDTNHYYHNVTSLHENGVESDANHSPAQLAQVSSTVSPRNTATTADTSFRPATENRDACGSSDLPPLLGQGLATVYTMHGNADCQQPTQAEIGHEWGSTAPTTWAMDDAASVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZS3</accession>
    <name>A0A9P6MZS3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Type i phosphodiesterase nucleotide pyrophosphatase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005962</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000294">
        <property type="protein sequence ID" value="KAG0019343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZS3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002591">
        <property type="entry name" value="Phosphodiest/P_Trfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01663">
        <property type="entry name" value="Phosphodiest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040242075" description="Type i phosphodiesterase nucleotide pyrophosphatase" evidence="1">
        <location>
            <begin position="23"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0019343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="451" mass="48018" checksum="ECEED5325FFB11E3" modified="2023-09-13" version="1">MKSISITISIALMMGALALGSAAEVKSCRRSDQSKFEHVLLFSIDGLHQADLADYIAAKPKSTFAGLVDSGVEFTNADTSKPSDSFPGLVAQLTGGHPVTTGVWYDIWYDRSLYTPGSDCTGAPGTITTFTQLIDIDPKDINGGGGTNLTALPRILKDGKCEPLYPHQYPRVNNLFQIARSHGLVTAWADKHTAAYDIARGTDGQGLTELYAPEIASVPVEVNATIAYDTLHVNAFLNWIKGKDALGEKQIGIPSVFGGNFQAVNVAQKNVGTPSAALSQAIDFVDASLGKVVAALKAAGIYEESVIIVSAINGNSPRDMNEIKRVNPAILPAVLGNVSISYTLTHDAGMFFLANQSDTFKAASSAYANADTSEPGTLFDISEADIAVHGGFNFDDINVPLIVSSPLFKKQKMTEHVETTQIAPTILCLLDLDPNELEAVQIEGTKVLPIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZZ0</accession>
    <name>A0A9P6MZZ0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004606</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000233">
        <property type="protein sequence ID" value="KAG0020206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZZ0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="425"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0020206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="956" mass="110756" checksum="F046F71FB6A40598" modified="2023-09-13" version="1">MSPSYDFPTEVFLHIGLYLNRQQLINSALVSKSWNAVFEPLVWSHLEIGSDKATSRIKVEDIRSKAPWIRSLAFKDFHSAVQFYSIGKGCTRLRSLALPITRSKEAVERGYWKVCKDLVKQNKATLVSLSLTFMPLTASNWNPLLSISQYPHSTLRSLRLENCKLPYRHLAAFWDVCERLEVLELHKVPFEPPYSYKVHEKAFGPKERPGWKVPFSNLLELILDCSGPRNSLTQLEVVIREAPKLKKLCWNIEEGAWFPITRFMYLFSGQEEYHYAPEPQNPDMTDQEIQDMSRAVFKQLGRLHKLRILDLSDDRNNPGWPLQFTESMGLASLSSLTELETLVLQGDQNMIPGDVDWMLEHWKSLKVIDGGMMAAQHYGRDCTLATMFNKRGIKTPRSVYPDEYLSNFGKNETDKCQILFHTQKMLQNRDLPNELYLQIGIYLNRCQLASCSLVCKSWNAAFGAQVWSRIELSSVSSIIQLTFEELSSKASCIRALEFLDCESTIRFSPIGKNCTQLRALSITTNGTSHRKDYWRACEEFIREIPRTLESLTLKRMPIPELRFKNGCYNWTPLLNVVQYPHPNLRTLRLESYVLPCVYIDAFWDLCERVQVLELQDVSFELPRLTRIQKRTKGVVAHQPRIVQFSNLRELTLIRSGPLNSLVQLEGIISGAPKLKKLYWTTRSKSWFPATRFIYLFTGQERYYRVLPPRVRPPYIRLEPCTAPSWPDLESLEDFVQKVLSSFPMLIKGHFQSISAQKFVDGGDSWVCFNSLEELKIQIKMYPQFYAPPRSDMTDQEKQEMSWAVFKQLAKFRNLRILDITNPRVCSSPTPQFTTSMGLPLLSSLTDLEVLRLEGEQDLAPQDVTWMIENWKSLRIVDAMKLAQNRTRFKEKNYWNYALADLFNKHGIKTPRSAFAYRKAGKRFSCDELDWSHYPYPPGDDGQAEVNPLEQIDVDFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N030</accession>
    <name>A0A9P6N030_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">glutamine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Glutaminyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BGZ80_004407</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>tRNA(Gln) + L-glutamine + ATP = L-glutaminyl-tRNA(Gln) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:20121"/>
            <dbReference type="Rhea" id="RHEA-COMP:9662"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.18"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.18" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010000225">
        <property type="protein sequence ID" value="KAG0020319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N030"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004819">
        <property type="term" value="F:glutamine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006425">
        <property type="term" value="P:glutaminyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.240.10:FF:000007">
        <property type="entry name" value="Glutamine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.2420:FF:000001">
        <property type="entry name" value="Glutamine--tRNA ligase cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.1290:FF:000002">
        <property type="entry name" value="Glutamine--tRNA ligase cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000037">
        <property type="entry name" value="Glutamine--tRNA ligase cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.1290">
        <property type="entry name" value="Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.240.10">
        <property type="entry name" value="Ribosomal Protein L25, Chain P"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007638">
        <property type="entry name" value="Gln-tRNA-synth_Ib_RNA-bd_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007639">
        <property type="entry name" value="Gln-tRNA-synth_Ib_RNA-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042558">
        <property type="entry name" value="Gln-tRNA-synth_Ib_RNA-bd_N_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042559">
        <property type="entry name" value="Gln-tRNA-synth_Ib_RNA-bd_N_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050132">
        <property type="entry name" value="Gln/Glu-tRNA_Ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020058">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020059">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_codon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020056">
        <property type="entry name" value="Rbsml_bL25/Gln-tRNA_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011035">
        <property type="entry name" value="Ribosomal_bL25/Gln-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049437">
        <property type="entry name" value="tRNA-synt_1c_C2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43097:SF4">
        <property type="entry name" value="GLUTAMINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43097">
        <property type="entry name" value="GLUTAMINE-TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00749">
        <property type="entry name" value="tRNA-synt_1c"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03950">
        <property type="entry name" value="tRNA-synt_1c_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20974">
        <property type="entry name" value="tRNA-synt_1c_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04558">
        <property type="entry name" value="tRNA_synt_1c_R1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04557">
        <property type="entry name" value="tRNA_synt_1c_R2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50715">
        <property type="entry name" value="Ribosomal protein L25-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutaminyl-tRNA synthetase class Ib non-specific RNA-binding" evidence="14">
        <location>
            <begin position="3"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="Glutaminyl-tRNA synthetase class Ib non-specific RNA-binding" evidence="13">
        <location>
            <begin position="164"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic" evidence="11">
        <location>
            <begin position="246"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="domain" description="Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic" evidence="11">
        <location>
            <begin position="423"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="domain" description="Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding" evidence="12">
        <location>
            <begin position="525"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA synthetases class I (E and Q) anti-codon binding" evidence="15">
        <location>
            <begin position="638"/>
            <end position="732"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF03950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF04558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF20974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0020319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="773" mass="87440" checksum="6B9B54B45CFEBB42" modified="2023-09-13" version="1">MSENLVVLFQNIGLTEQKAKETAKNKNLAPTLERVINTAGFQNKPSEKGTGALLYHLASTSTPAAAPHLDYIAEAIRDSKLTTSDQVAAAIKFVSNKTNIDEAAFNEECGVGVIVTKDDVKKAVDSYTETVKDKLIQDRYKYFGLFFAGAKNIPSLKWANGGDIKEAVDAKMLEVLGPKDERDVVVKKKKETKPEVKEEVKVNVLKVPDMFFEGELAKLHKPGENPQINPELMKEHLKATGGKYITRFPPEPNGFLHIGHAKAININFGLAAAHNGICNLRYDDTNPEAEEERYFESILEIVKWLGFTPSEVTYSSTHFQRLYDLAVELIKKDKAYVCHCTGEEIQKHRGGPERGPRTACVHRDRPIKESLELFEKMKNGGFEEGEAILRMKMDLENGNPQFWDLVAYRVLKAAHHRTGSEWSRPSYYWLCDALEVYKPVQWEYGRLNITNTVLSKRKIAELVKKGYVFDWDDPRLFTLPAIRRRGVPPQAINNFIHTLGVTKSDTVIEVTKLDAFIRDFLNETAPRLMGVFDPIKVVIENLPEGFEQMLTVPNKPRDPSMGERTIPFTREVWIDGSDFREVDDKDFFRLAPGKTVGLLNVPYPITCTKVVKDNAGKVVELVVRYENVDGFKPPKTYIQWVAESPKHGSPVRLDEVRLFERLFNHANPQDKREVPGGYLSDINPNSLKIEKGAFIEVGLWDIMDRWIKSSESKTDFEAMRFQLIRIGYFCVDRESDLGDLKASSGASIKDKVKKIVLNKTVGLQVSSTLKNKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N136</accession>
    <name>A0A9P6N136_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Tail specific protease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_004987</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000249">
        <property type="protein sequence ID" value="KAG0019969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N136"/>
    <dbReference type="OrthoDB" id="27214at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056186">
        <property type="entry name" value="PDZ_CPAF-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052766">
        <property type="entry name" value="S41A_metabolite_peptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005151">
        <property type="entry name" value="Tail-specific_protease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37049">
        <property type="entry name" value="PEPTIDASE S41 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37049:SF4">
        <property type="entry name" value="RHODANESE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23658">
        <property type="entry name" value="PDZ_CPAF_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03572">
        <property type="entry name" value="Peptidase_S41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040406167" description="Tail specific protease domain-containing protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="domain" description="CPAF-like PDZ" evidence="4">
        <location>
            <begin position="204"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="Tail specific protease" evidence="3">
        <location>
            <begin position="472"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF23658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0019969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="744" mass="81423" checksum="51E4DA83F1CB9CE6" modified="2023-09-13" version="1">MKLTSILTLAAALYVVSADPQSSHTSAKSLESQTTTTTTIAHAKHSPIATFDDKKKSTKTKSHAKATKTKSLKASKTKAPKLVDACGLMNQQASKSDYMLTYEAVKGCFEAQKFKPDVANKVLTSVENLLGNFYAFLDQAKVSSSGAGSPFDTPVVDLMKELEKIKKKKDWKSDYEFQMALTYLTFSLNDGHLAYQNSCYKTVSFNQPISLYAPIVDGKQSVRVFYVDTTMSKKGLPKDPSSLIDCTVVTIDGEPALKAIQDFTDRTSAISKDPGVRLNDALASTSWNTDWSFSPGGFASRWILPAKSSMDYTLQCGSGANIKTQKLTVPWTIRPSDSFEVGEFKNANEYWKVQCESYTPSSPSSRENVKRDLAFPPTHAPRRGDVRIQDGGASATVPATSLFRERGTITIPTTSGPSDDRSGDSKKGSSIITQAKLVKTTSNVAFYHLLGKNSDTCVAVIASEEANFSEYDSSDYTGFIKALQTLEAQGCKKLILDMTNNGGGSVDYAYFVNQLLFPDAKPYFVEDLRDNSLTQAAAKQAMKYPKAHSVFDARGYNSAATGKPFKDATMFTKGVNQKRGGVTSTYTQRNFFPYSWSFLPLAKSKQLKFKPENMAIVTNGFCGSACTMIATRFAIVHNVKTYAIGGIAKRPLSYFSFPGGFVLQDSDIISDLNSIHLKGVKNVPTTLPIQASTSLPVGEIYALNNSTIPLEYDTQYFAAKVHLDQDPVLARHPDKVWVKIANDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1B6</accession>
    <name>A0A9P6N1B6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Proteasome assembly chaperone 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004674</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000236">
        <property type="protein sequence ID" value="KAG0020169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1B6"/>
    <dbReference type="OrthoDB" id="17536at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043248">
        <property type="term" value="P:proteasome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016565">
        <property type="entry name" value="Proteasome_assmbl_chp_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37227">
        <property type="entry name" value="OS01G0219000 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37227:SF2">
        <property type="entry name" value="OS01G0219000 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16094">
        <property type="entry name" value="PAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0020169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="267" mass="29132" checksum="A83D4DD70107BFEE" modified="2023-09-13" version="1">MDSEDDHHRYQSSDEEDFQESVEKAVTLPKPIVLWRTATLPKTCSTLIIGTAFGASTLLHTVKAKTLLGTLILPGVDLKDNTLDVNARTNASCNIYELDADPTVVIIPCNYEIKDQNSLNFAKAIMNNIQASRIIILDTLSPSTYLSGSPDTEYNYPWLRLLQTAGSTTVTKIPALEVPNLVQNLGAALMSYCEVRGQSDTYLLLSLQEHVYGKALTTAATLRGLKEGLASLGCPLVANEVDVTAAVVSIQDKRVGSNRTRDDRLYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N273</accession>
    <name>A0A9P6N273_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001559</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000136">
        <property type="protein sequence ID" value="KAG0021851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N273"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="356"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="551"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="356"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="386"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="424"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0021851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="578" mass="62770" checksum="ACFA1AB25A30A78B" modified="2023-09-13" version="1">MNPLAGSMQVFEFQADSSVSLVSTAAINRKSCDHCFLNRKTCDKVRQADSGEKCKRCAKDNRPCTFTPTVHLYHIADCVGRHQCRAKVIQAMGGVKKEVQFKTIEIPIVCDMDNDIDRTLFEYIQKNPNLLVYNNRIKSFLAQEMLGISPDHDPVSNTPYGQSVLNYVRKDTFLSSQVSCILYTNPYIALIDQQIPPPSVNVRGSFSGDQYGGGSNPLTSPMQGPAKPYVPHRPHPYLNASPRAHPAQNVVRHGSMNSEVFTGFTNGGIPGSQVSPSASPLSLSPLDSAAVLGFDQRRHSNGFVADMTASVNPYGGAYQQVQPFQQQQQQHHPYAAQSPYPQPQFFVNNNSYRRTPSPFSTSPVAPSPIQQYTSQPPSPLELSLSAGTNLGTLSNNSHQNLTSLFDNNMTMGNQSSQSLHRRQPSMSSLSASSSASPAMSNNNQGGDMPTPGSSAPMVITTLNEDGHEVGFYYAVPAVSLNPGASDADLFQDFTVMEDTLGENFVWVENLFDENATGVVAGDASGSNLSPSSAIPIPGAGVSESMMMEGLLAQQRQQHDEWSSQYAPQDSYDNHTLQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N283</accession>
    <name>A0A9P6N283_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Aureobasidin resistance protein Aur1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">IPC1_1</name>
        <name evidence="8" type="ORF">BGZ80_000860</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000119">
        <property type="protein sequence ID" value="KAG0022170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N283"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070916">
        <property type="term" value="C:inositol phosphoceramide synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006676">
        <property type="term" value="P:mannosyl diphosphorylinositol ceramide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030148">
        <property type="term" value="P:sphingolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03386">
        <property type="entry name" value="PAP2_Aur1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.144.10">
        <property type="entry name" value="Phosphatidic acid phosphatase type 2/haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026841">
        <property type="entry name" value="Aur1/Ipt1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052185">
        <property type="entry name" value="IPC_Synthase-Related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="PAP2/HPO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31310:SF11">
        <property type="entry name" value="INOSITOL PHOSPHORYLCERAMIDE SYNTHASE CATALYTIC SUBUNIT AUR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14378">
        <property type="entry name" value="PAP2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00014">
        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="140"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="284"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatidic acid phosphatase type 2/haloperoxidase" evidence="7">
        <location>
            <begin position="177"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="375"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="421"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="485"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="381"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="422"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="536"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0022170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="575" mass="63775" checksum="7C10DBCEE2BB6083" modified="2023-09-13" version="1">MVSFSNLRLRCDNIQTSIKAAVISTIRPLQKHRYTLYDLQYVFLFILFSFCYYIMEKPVWFKLPIALGAIGLLIPKKTRQFMLPFLAIAAWLILFYCCRFIPSEWRPHIFTSVLPTLENILYGGNISEMLAQTTSPVKDLLAWMPYGVIHFALPFITAILIVFFGPPGTLPVFARTFGYMNLAGYETNYGSFEPATYAMPGSPGGLARVDDILGLDMYKSTFTASPLVFGAFPSLHSACAWQLAFFLVFIFGPRSIPFVVGYVFWIWWATMYLGHHYVVDLVGGAGYAVVAFWIGSFFLPSVLPQYHNEKAAHVIHDLGDAMNYQEKQTLFDAAHGDDFVGYGYNKEWNGNESEDRDEEFEEIANMVVVKIEQEMEERTFSQSEPSSPSSPAVSKKSEQRQTWSGWHGYESWMEVLATVNTPRSSPRHTPSSSPRGSFAHGYPGRPRNSRESMYSTSSTSTLNLDLEANVALVQGSSSLSVIEEASGSSGHGISSVAMGKGRSRPSRLVLEGSAGYSGSMPNSPLADHAETDSESSRSGSSRPTSPRSVASRPTTPRSFVSGALSPAILKRVKDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2M0</accession>
    <name>A0A9P6N2M0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Mitochondrial Translation Optimization</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">MTO1</name>
        <name evidence="7" type="ORF">BGZ80_010839</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MnmG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000080">
        <property type="protein sequence ID" value="KAG0022924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N2M0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070899">
        <property type="term" value="P:mitochondrial tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000145">
        <property type="entry name" value="tRNA uridine 5-carboxymethylaminomethyl modification enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.570:FF:000001">
        <property type="entry name" value="tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.570">
        <property type="entry name" value="GidA associated domain, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049312">
        <property type="entry name" value="GIDA_C_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002218">
        <property type="entry name" value="MnmG-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020595">
        <property type="entry name" value="MnmG-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026904">
        <property type="entry name" value="MnmG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047001">
        <property type="entry name" value="MnmG_C_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044920">
        <property type="entry name" value="MnmG_C_subdom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040131">
        <property type="entry name" value="MnmG_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11806">
        <property type="entry name" value="GLUCOSE INHIBITED DIVISION PROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11806:SF0">
        <property type="entry name" value="PROTEIN MTO1 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01134">
        <property type="entry name" value="GIDA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21680">
        <property type="entry name" value="GIDA_C_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13932">
        <property type="entry name" value="SAM_GIDA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SMART" id="SM01228">
        <property type="entry name" value="GIDA_assoc_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01280">
        <property type="entry name" value="GIDA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain" evidence="6">
        <location>
            <begin position="588"/>
            <end position="659"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0022924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="694" mass="76791" checksum="0F6A0FE83CE75700" modified="2023-09-13" version="1">MFQVSKRLLLVSHSTTVSGSSRSTFSTLASRSRVATRVLRHNTQVWSTQSRHTGQFRSVTLAASQALPPTPETSYDVIVVGGGHAGSEACAAAARTGAKTLLLTQKLDTIGEMSCNPSFGGVGKGVLVREIDALDGLCGRISDLAGVQFRILNRSKGPAVHGPRAQIDRKLYKKHMQKALHEYPNLTIKAGSVSDIVLGAEILPPTPGQNTVQGEIKGIKLESSEVIHAPKVIITTGTFLRGEIHIGLEAYPAGRINEEASIGLSDSLAQAGFELSRLKTGTPPRLDGKTIDYSRLTPQHGDMPPLPFSFLNKEVANAHNQLLCYQTSTNPKTHEIIRNNLHKSIHIRETVKGPRYCPSIESKIMRFATKEAHTIWLEPEGYDTDVVYPNGISMTLPEKEQIEMLRTIKGLENVTVLRCGYGYEEAAAQGILAGINAGLAAQSKPPLILTRADAYIGVLVDDLITKGVEEPYRIFTSRSEYRLTLRADNADLRLTRKGYEAGCVTEYRWNAYQRMEQEMNRGIELMSEFKLSPAKWAEYGLGKSDDGVKRSAIDMLSFPNIKMEDFYEAIPELKEIDPFTQAKIEVEGAYSVYLRRQGAEVTAFMRDESMELPSDLDYSVIPNLSNENRSKLERVRPATLGAAKRIEGMTPTSILELLKYVQRTKRPATMANGEPIRSGSRKERLRQRMLAKEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N303</accession>
    <name>A0A9P6N303_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Translocation protein SEC62</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">SEC62</name>
        <name evidence="13" type="ORF">BGZ80_001527</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SEC62 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000135">
        <property type="protein sequence ID" value="KAG0021885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N303"/>
    <dbReference type="OrthoDB" id="200187at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031204">
        <property type="term" value="P:post-translational protein targeting to membrane, translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004728">
        <property type="entry name" value="Sec62"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011553">
        <property type="entry name" value="Sec62_asco"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00869">
        <property type="entry name" value="sec62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12443">
        <property type="entry name" value="TRANSLOCATION PROTEIN SEC62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12443:SF9">
        <property type="entry name" value="TRANSLOCATION PROTEIN SEC62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03839">
        <property type="entry name" value="Sec62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0811">Translocation</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="129"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="155"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="217"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0021885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="268" mass="30336" checksum="C8976B19B0BF95E0" modified="2023-09-13" version="1">MDANVPPQRPKNLCQVADYLLSPQSGLKKRDGVFHETRVTYFRGKGAVNSLLKPEFRQTAVGKELGELTRESAAELLGSMIPHQFFLKVERPSDPEMPRNMLSLVQYQSFTEDGVYLWRYEGSQLRTHLMAGGLLLIVLAGVMFPLWPVPLRLGVWYLSVGVLILLGLFFAMAIFRLILFMITWVVLKPGIWLFPNLFEDVGFVDSFIPLWGWHEPEEPKESKKASKKIASGEEAEEVVQTQVVSDETAEKIIKRKPMVEDVADEDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3J7</accession>
    <name>A0A9P6N3J7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Integral membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_000488</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000110">
        <property type="protein sequence ID" value="KAG0022347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3J7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040243326" description="Integral membrane protein" evidence="2">
        <location>
            <begin position="26"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="92"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="141"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0022347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="198" mass="21043" checksum="1617A3CE49D6B457" modified="2023-09-13" version="1">MTRQSRFNWLTIAVLLLKPMTIISALQLLKFRGDPFSSFGGGMNWTGRSHGYEGGGLGGYQTLGDALDYDRDAEEISIPRHHSQMHGIHRNSQQSGSFFTTSSRSTSVKSSRTGSGHNVELGPNTSVSSPGAHHGNDHNFGSPASAVIASVGGGGAAKDDRRDRVGQNTSEDEDEDASSRDTSAQGGPDNTRAGYQAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N412</accession>
    <name>A0A9P6N412_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cyclin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_010999</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000083">
        <property type="protein sequence ID" value="KAG0022848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N412"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000307">
        <property type="term" value="C:cyclin-dependent protein kinase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20557">
        <property type="entry name" value="CYCLIN_ScPCL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013922">
        <property type="entry name" value="Cyclin_PHO80-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615:SF108">
        <property type="entry name" value="PROTEIN CNPPD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin N-terminal" evidence="2">
        <location>
            <begin position="119"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0022848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="252" mass="27492" checksum="B6DA4F7096D63296" modified="2023-09-13" version="1">MDSPSSSTYSSLPSSSSSSWSATSSEVDLPDQMQKQLQLQQQRYIDLPMSSCSPCSEELLSLAAVTVLSVLQCPPSLPVSRSSSLIFKSPAAVSLPATAVAIMTAATSTMSEAAKEQHVQFLNFLRNVCIKATVTELALVVSLIYVDRLKKVLTNMARGDPDTPFKIILSALLVVKKFIEEDCIGLNRMFSKITDGLYSVHDINTMERSFLGLLKFSLYVTEKDVFNFIQSHQKELQGVEIIKSLSNPAAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4H9</accession>
    <name>A0A9P6N4H9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Prephenate dehydrogenase [NADP(+)]</fullName>
            <shortName evidence="2">PRDH</shortName>
            <ecNumber evidence="2">1.3.1.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">TYR1</name>
        <name evidence="4" type="ORF">BGZ80_009005</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>prephenate + NADP(+) = 3-(4-hydroxyphenyl)pyruvate + CO2 + NADPH</text>
            <dbReference type="Rhea" id="RHEA:21640"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:29934"/>
            <dbReference type="ChEBI" id="CHEBI:36242"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.3.1.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-tyrosine biosynthesis; (4-hydroxyphenyl)pyruvate from prephenate (NADP(+) route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the prephenate/arogenate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.13" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010000051">
        <property type="protein sequence ID" value="KAG0023572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N4H9"/>
    <dbReference type="OrthoDB" id="5399569at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008977">
        <property type="term" value="F:prephenate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004665">
        <property type="term" value="F:prephenate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006571">
        <property type="term" value="P:tyrosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000339">
        <property type="entry name" value="Prephenate dehydrogenase [NADP(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3660.10">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028939">
        <property type="entry name" value="P5C_Rdtase_cat_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050812">
        <property type="entry name" value="Preph/Arog_dehydrog"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003099">
        <property type="entry name" value="Prephen_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012385">
        <property type="entry name" value="Prephenate_DH_fun"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21363">
        <property type="entry name" value="PREPHENATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21363:SF0">
        <property type="entry name" value="PREPHENATE DEHYDROGENASE [NADP(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03807">
        <property type="entry name" value="F420_oxidored"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036510">
        <property type="entry name" value="PDH_fung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51176">
        <property type="entry name" value="PDH_ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="1 2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0827">Tyrosine biosynthesis</keyword>
    <feature type="domain" description="Prephenate/arogenate dehydrogenase" evidence="3">
        <location>
            <begin position="13"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR036510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0023572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="437" mass="49629" checksum="1539553A924CD150" modified="2023-09-13" version="1">MPNNATDSEKETIQLGIIGMGDMGKLYARTLFAAGWKKVNVCDMPEKYDQLSNEFRDTGITVMRDGHLVSRQSDWILYSVPAEFIDNVVATYGPSTKIGAIVAGQTSVKAPEIAAFEKHLPEDVHIITCHSLHGPTVSPRGQPLVIINHRGSAEKLALVERILSCFESEIAHLTYKEHDRITADTQAVTHMAFLSMGTTWRHQNSFPWFDPTYTGGIENVKVNMTMRILSNKWHVYAGLAILNPSAKAQVRQYSLSVAALFKLMIQEKEAEFVARIRAAGEFVFGNRGDREHILLSDNLLDQYSLGSVPKEKIKPNSHLSLLAMVDCWHQLKMNPYSHMVCQTPIFRFWLGISEYLFLNEEYLQDAIQAALYDKDIREDDMEFMMSARGWQECIALGNMEGYRLRFEDTSRFFQDRFGEAAVIGKQMIEMITRKTVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4T2</accession>
    <name>A0A9P6N4T2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Kinesin-like protein kif21b</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">KIF21B</name>
        <name evidence="15" type="ORF">BGZ80_010836</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000008">
        <property type="protein sequence ID" value="KAG0024679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005875">
        <property type="term" value="C:microtubule associated complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051231">
        <property type="term" value="P:spindle elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01372">
        <property type="entry name" value="KISc_KIF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.850.10:FF:000011">
        <property type="entry name" value="Kinesin family member 21A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47969">
        <property type="entry name" value="CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47969:SF15">
        <property type="entry name" value="CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25764">
        <property type="entry name" value="KIF21A_4th"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="9 11" id="KW-0505">Motor protein</keyword>
    <keyword evidence="6 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Kinesin motor" evidence="14">
        <location>
            <begin position="4"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="226"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="489"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="628"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="689"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="750"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="858"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1091"/>
            <end position="1137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1377"/>
            <end position="1449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1503"/>
            <end position="1653"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1683"/>
            <end position="1792"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="2017"/>
            <end position="2038"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="2271"/>
            <end position="2298"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="370"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="462"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="935"/>
            <end position="1079"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="1166"/>
            <end position="1196"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="1326"/>
            <end position="1353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="226"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="514"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="692"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="877"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="1402"/>
            <end position="1415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="1526"/>
            <end position="1535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="13">
        <location>
            <begin position="1558"/>
            <end position="1567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="1686"/>
            <end position="1731"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="2024"/>
            <end position="2035"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="2287"/>
            <end position="2298"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="84"/>
            <end position="91"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0024679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="2311" mass="253588" checksum="4D7F4F6D7EC319A8" modified="2023-09-13" version="1">MNTAVKVALRVRPLTLQEQINNCSECISYVPNEPQIGIVGSDKSFTFDYVFDEETAQRDVYERCAKELVDRFVEGFNVTILAYGQTGSGKTYSMGTGIQYQNADQAIVPRAAHAIFSQLNAQMEKDPAMEYQVYVSFLELYNEELIDLLQTQPRTRKDTIQVREDGFGGISWQGVKEQQVNSAQELLDWLQKGTLCRTTAATDMNQTSSRSHAIFSVVLKQQRSEEIEEINENEEQASPSAAPAKTNDKSIKKFASKFHFVDLAGSERLKRTRAVGDRAKEGISINAGLLALGNVISALGDESRKSSHIPYRDSKLTRLLQDSLGGNSATLMLACVSGADADINETISTLVYANRARNIRNRVVINQDFRDSNNAEIAHLRAEINRLRMENSAFKAMGSGPAAELDQRRAAEEMRSLRGEVARLRERLKESSSELCDVLAERDTLLVERECQGDNIEAHPIMQTYHRTVMQLKDRLIAAEDQALELQTLLSQKPNAPDSRRKAPSPYKKRAEPLSDDDHDADGEHDEDTQRRKDSSPPRGRQSKRRSRQSSRAASRFDFGLTSAGLSMEPAKLPDSPPVPEVEQILSSGGASSWFQNLKTEENQPMSATLDYSSTSSSSMLQRFTVDSDSSHDFSRRRRAARNGSGGVVENLDKGKEDIRKGLLLLNAEKNGMGMDMELLNLLTDPNALAKSGSASSRRRSSMTSSMSSGSSNRSRFQTHQPLPTLEDVINNGSPISPLRASFPFPPPPGVSSWRDAPSVPSWKDSAPSVASWRESAPSVSSGREAPSVVSWKETTASPQDQKVFFEAEQKAAETLANAMKAMHRFSFPLSMTDTQQISQQQQQTRLAMAIQQQKASGIALPDSDTGSIHAASVHSGSHRSHHSHHSFRESHSARGSFRAPSHSVFDSNATHKSSEKPNYGEEMLNEVQSGLAIKEELVSQLERAEHDYNNMRSQYEEEIRIPGSVKVKYETKIKQLMSELSDLQHKYADVSKIANEKRTLAENQLRTLRVAVETLKAEKARMIKRMKEDAERIKEINAANDREIQALRRAEKAAVDGRKKAEREAEQQRATALLHRNNASGQNNQQAKVNFLKKPQSPKGITKAPKRVPRLGGPSERADSKGSSVPAPKSKAQASSIRLKVAQKKQVIDRAIYGYISGQHAINVMEDLLKKRQRLRSEKQELEQERERVVRSQEENAIANGTVLLDFNSEPQYMDDRLAMIDAEVAYINARIRALQAEAAALGFVTAIEKTSDSKDGSTTSDEEEMVTKLIRQGMADDAMGLPPGSGAAVAFESSISILRSLDVYEAREFLEMLFEDMVSVRSNENTLLVQVKNQEKVIEELKRALLAMRQAAVGATLGYEKRCGGLEQKVRQLGGSSEDIASISRPNLDNSSEEDENDAEVARLSRSVFRDGETTSPILSRESKDTPWTPLPDNALPRSGSAAEAVLDDKSKRASTIFDQMYEEAIKTSDETSPKVGGTGGEFSRMLMANHNRRVSWAGVPASENEDASSAPPPQQSEQRQRLARSQSTSAINQRAAADRTEVKGRAIAHRRGGSTSSGGSGGAHGLPPVPPNRNSNRLSIGGEAQLRGPFASTASSRQHAESVASRRSSTPVSSPAIGKRLTRSDSDGAGFASPTAASMARMQNGNSRPLSRIGAASMMTTTPTATNIVNGLASPALHGFNTADGQSEQFHTHHYNGSSRRVSGSWDDNQNNQSVYDRLASSHTQASQARIAAQRHSGHFAQPSTPAGGKMMRRPSVDLTAQSESVDVHGEQNWPSNSSSSSAEDAAYPESIPGFPKSEVTPAKLDNMNEKSDTSIPMRTEEDLLLGGRQAPQGCTRRIFCKRCVAGAHKNSKKRVFLRRTFAAMFLVWFCYSIYGYRRLHGINSGVGHEGGRHGGHDGYQCHRDNLIAWDGPSEIETNARNIDFKFGKGNMATNIAVLTNDEIDEPVITITANVTKTHPLYDGDDDDEFQNEGVTILDANTKEFHRHGLHVQVIEIDGDLAITIWADEYADHGHHHHHHDHDDEHHNDDHPHHHHRKFCANIEAAVILPQAFAKFGRLSIVGTIMDVDVRDVSGITFERFHISTAIGRVTVHRSEGDYIGTGGVLAKDLSVHGITGPITVPTISAPEGSPTKVNVTTSVGSIDLNVVLPQIAANAEDQKHEISITSITGDIQVGVRPTAGGDDGKAHSKSASVVPGEAHLKLNSEVGQIHTSVDLADHQVLFLSSGSTTGLVSTKVSDKFLGSIKLQTEIGSTKVIEAEDSASEIDFEKNTNHVKSGRKQLKGKPDGNDEGEIDLRSRFGRSELIFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N6E2</accession>
    <name>A0A9P6N6E2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">60S ribosomal protein L7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RPL7</name>
        <name evidence="6" type="ORF">BGZ80_004769</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL30 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000024">
        <property type="protein sequence ID" value="KAG0024255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N6E2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
        <property type="term" value="P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01657">
        <property type="entry name" value="Ribosomal_L7_archeal_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1390.20:FF:000002">
        <property type="entry name" value="60S ribosomal protein L7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1390.20:FF:000003">
        <property type="entry name" value="60S ribosomal protein L7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.20">
        <property type="entry name" value="Ribosomal protein L30, ferredoxin-like fold domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036919">
        <property type="entry name" value="Ribo_uL30_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039699">
        <property type="entry name" value="Ribosomal_uL30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018038">
        <property type="entry name" value="Ribosomal_uL30_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005998">
        <property type="entry name" value="Ribosomal_uL30_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035808">
        <property type="entry name" value="Ribosomal_uL30_euk_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016082">
        <property type="entry name" value="Ribosomal_uL30_ferredoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012988">
        <property type="entry name" value="Ribosomal_uL30_N_euk"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01310">
        <property type="entry name" value="uL30_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11524">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11524:SF16">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00327">
        <property type="entry name" value="Ribosomal_L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08079">
        <property type="entry name" value="Ribosomal_L30_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55129">
        <property type="entry name" value="Ribosomal protein L30p/L7e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00634">
        <property type="entry name" value="RIBOSOMAL_L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL30 N-terminal eukaryotes" evidence="5">
        <location>
            <begin position="13"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL30-like ferredoxin-like fold" evidence="4">
        <location>
            <begin position="89"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0024255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="248" mass="28271" checksum="F8394FA0E1847014" modified="2023-09-13" version="1">MTTTTPTLNHVLVPETLLKKRKTQEKAAAEKLTADVAARKARKAQRKVIFKRAEKYIREYHAKERDEIRLRRQAKATGSFYVPAQPKLAFVIRIKGINHIAPKPRKVLQLLRLLQINNGVFVRLTKATTQMLQLINPYIAYGEPNLKSVRELIYKRGYGKVNKQRIPLTDNSIIEKALGKFGIVCIEDLIHEIYTVGPHFKQASNFLWPFKLSNATGGFSAKKALHFIEGGDSGDREAKINKLIRQMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SRF8</accession>
    <name>A0A9P6SRF8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_008566</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004680">
        <property type="protein sequence ID" value="KAF9992411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SRF8"/>
    <dbReference type="OrthoDB" id="10259681at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009922">
        <property type="term" value="F:fatty acid elongase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002076">
        <property type="entry name" value="ELO_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01151">
        <property type="entry name" value="ELO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="104"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9992411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="147" mass="16505" checksum="5F7FC6987C2B49B0" modified="2023-09-13" version="1" fragment="single">MESISTFVKPPQDLFIDFARAVGVHAAPYVDPVEAALITQLEKYFPVAVHHVRGFLVSVESPLAQELPLMNPFHVLLITLGYLIVVFLGMQIMKNFNRFEVKTFSLLHNFALVSISAYMCGGILYEAYQAKYTLFENLADHSIKGLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SS00</accession>
    <name>A0A9P6SS00_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">WD40 repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_007905</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004141">
        <property type="protein sequence ID" value="KAF9994158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SS00"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990234">
        <property type="term" value="C:transferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847:SF637">
        <property type="entry name" value="WD REPEAT DOMAIN 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="35"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="76"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="126"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="161"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="203"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="245"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="287"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="329"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="370"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9994158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="423" mass="46098" checksum="C5DA8EA5BE728B94" modified="2023-09-13" version="1" fragment="single">AVFSPDGTYIAFGTFGDENIVWLYEVATGTEVYAFKGHGDRITSVAFSPNGDRIASGSYDNTIRLWDVNTKESIELKGHEECITTIAYSPNGNQIASSSDDYTVRLWDVFSGDCLHVLKDNTDFSVTNVVYSPNGEQIASVNYDKTVQLWNVESGECIHTLEGHNETLTGVAYSPDGTHIASASEDKTVRLWDVETGKCLHILWGHTDHVTNVMYSPRGDQLATGSLDKTVRLWHSDTGDCLQILNGNSDDITSLKYSPQGDRIASGNNGKSVRVWNVDTGLSVHATDSHSGEVQAIALSSKGDQIASGSNDHTVRIWDVETGHCIRTLAGHTEPVISVKYSPNGDLIASASNDDTVRLWDAKTGNDVNKFEHRGRVTSIAFAPNGKHIACGSSNRTVYLWDVKTGKCEHTLIDDGRATVILK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SSM3</accession>
    <name>A0A9P6SSM3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_007052</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003545">
        <property type="protein sequence ID" value="KAF9997234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SSM3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00022">
        <property type="entry name" value="BIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1170.10">
        <property type="entry name" value="Inhibitor Of Apoptosis Protein (2mihbC-IAP-1), Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051190">
        <property type="entry name" value="Baculoviral_IAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001370">
        <property type="entry name" value="BIR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46771">
        <property type="entry name" value="DETERIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46771:SF5">
        <property type="entry name" value="DETERIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00653">
        <property type="entry name" value="BIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00238">
        <property type="entry name" value="BIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57924">
        <property type="entry name" value="Inhibitor of apoptosis (IAP) repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50143">
        <property type="entry name" value="BIR_REPEAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9997234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="135" mass="15651" checksum="2F322A92C0EC20DC" modified="2023-09-13" version="1" fragment="single">MQSTDARLKSFNHRTRSWPYSEDSYKANPGTLADAGFYWKPALSSQDNVMCFLCGKSLDGWTDTDDPYDEHLSHSRTCGWAIVKSIPLVDDGELPFRWDDEDELPKGERMTKARIQTFGNWWPHENKGWYGTVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6STC9</accession>
    <name>A0A9P6STC9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Serine/threonine-protein kinase RIO2</fullName>
            <ecNumber evidence="4">2.7.11.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">Serine/threonine-protein kinase rio2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">BGZ80_006443</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="4"/>
    <dbReference type="EMBL" id="JAAAID010003181">
        <property type="protein sequence ID" value="KAG0000028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6STC9"/>
    <dbReference type="OrthoDB" id="10258631at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030688">
        <property type="term" value="C:preribosome, small subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05144">
        <property type="entry name" value="RIO2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000053">
        <property type="entry name" value="Serine/threonine-protein kinase RIO2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000307">
        <property type="entry name" value="Serine/threonine-protein kinase RIO2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000052">
        <property type="entry name" value="Serine/threonine-protein kinase RIO2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030484">
        <property type="entry name" value="Rio2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015285">
        <property type="entry name" value="RIO2_wHTH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018934">
        <property type="entry name" value="RIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000687">
        <property type="entry name" value="RIO_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018935">
        <property type="entry name" value="RIO_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45852">
        <property type="entry name" value="SER/THR-PROTEIN KINASE RIO2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45852:SF1">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE RIO2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01163">
        <property type="entry name" value="RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09202">
        <property type="entry name" value="Rio2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00090">
        <property type="entry name" value="RIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01245">
        <property type="entry name" value="RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0418">Kinase</keyword>
    <keyword evidence="14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RIO kinase" evidence="20">
        <location>
            <begin position="65"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="314"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="19">
        <location>
            <begin position="337"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="391"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="19">
        <location>
            <begin position="404"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="426"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="19">
        <location>
            <begin position="443"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="486"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00068353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00068837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="SMART" id="SM00090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAG0000028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="509" mass="58187" checksum="457DF2F233CE6ADA" modified="2023-09-13" version="1">MKLDAKVLRYMSPEDFRVLVATEMGSKNHEVVPSPIISQIAKLRHGGSHKILSELARRNLVAKVQHIKYDGYRLTYGGYDYLALRTFCQRNSVYSVGNQIGVGKESDIYIVANEEERQMVLKIQRLGRMSFRTIKSKRDYLKNRKSASWMYMSKLAAEKEYAFMKVLHENGFPVPEPIDQNRHCIVMELIDAFPLRQISDVANPGKLYSNLMNLIVKLASYGLIHGDFNEFNILIRDNGEAVLIDFPQMVSIDHPNAEYYFNRDVECIRVFFKRRFQYESLLYPKFKLDTERQFALDVQVAASGFTKEKQQELEKFQEEEGQLAQELGEDAYRRSDDENEEVESDEEEESEEEEEEESEEETNDGTQESEELPVPFGKLSLANLSQLDQQSGSGPRNNSNPGSDNDDEENEENDSVGSLDGPINNREFKAYRDVKPKVAGSVAGSTRSKMTKSSGPMSPEEIKARVAQNLRSGSRIKFSAKQNHSKGTDKRDRRKVAGERAHIKYGSEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SUF9</accession>
    <name>A0A9P6SUF9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Peptidase S8/S53 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_005671</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002791">
        <property type="protein sequence ID" value="KAG0004130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SUF9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF66">
        <property type="entry name" value="SERIN ENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0720">Serine protease</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040110463" description="Peptidase S8/S53 domain-containing protein" evidence="6">
        <location>
            <begin position="19"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="7">
        <location>
            <begin position="138"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0004130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="269" mass="28754" checksum="F4F1D0E54FABB458" modified="2023-09-13" version="1" fragment="single">MKISAILSTLAAATLVSAGKLHHLKQANSHPIVPNAYIIEYESNISHSDAHKALKAHSVDYHVRNEYDIFKGSAITVKSDHDGEHIAAIPGIKNVWPITLHKPPKIIKSTKKATDPQVVSDHHMTGVDVVHEKYHLTGKGVKVGIIDTGVDYKHPAFAASGATEGCFARYGKNCRVAHGWDFVGDDYTGYNTPVPDADPMDCFGHGTHVAGIVGGNALNIKVSPKPPQPFVGVAPEVTFGAYRIFGCDGSAGDDVILAAMELAFNDGMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SVR0</accession>
    <name>A0A9P6SVR0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Mitochondrial carrier</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BGZ80_004689</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002368">
        <property type="protein sequence ID" value="KAG0007406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SVR0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990542">
        <property type="term" value="P:mitochondrial transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045315">
        <property type="entry name" value="Mtm1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45760">
        <property type="entry name" value="FI19922P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45760:SF2">
        <property type="entry name" value="FI19922P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="196"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="348"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="27"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="154"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="443"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="165"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="443"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="467"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0007406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="493" mass="53139" checksum="07F99FD53E7BA174" modified="2023-09-13" version="1">MGDHSLSQRPIAASPIITAALSAAGSTEVPQPQSPYVSAISNAPSTESPKQDSGSIQPSTAQRMISACAGSLLTSLLVTPLDVVKTRLQSQTVAATPTCAPPFTYTSDASAYEKLCTCCREVFFAPQTHNPQQQQQLTGVRGIRQNIAKVLASRKRVGSAFSRSQKNRPGHSHDHHHSHNHNHSRTRGTTAGCGPSIIQQHQEGTVIAMKSTRVQQQRLEQLAANCIENNHTSKAAQERHFYGTWDGVKKIVRYEGATSLWRGLSPTVAMSIPATVIYFVGYDHLKDILSEKVFMTSPENDVFLGQSFVYEYRSTLAPLIAGGFARRYESIKRRIVAWDSQHAQPVLNEFGIAFTSGAASGMFAATVTTPFDVAKTRRQVDLTQPTHTRMTSLMKAIVRDEGYRGLWRGLTARVAKVAPSCAIMISSYEVGKKALSEQWWGLGSSSSSSSSSPPSPSPSSTGPSGANAGGNSGGVRGVDDQIAILRDNRQAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SW23</accession>
    <name>A0A9P6SW23_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">poly(A)-specific ribonuclease</fullName>
            <ecNumber evidence="5">3.1.13.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">CNOT7</name>
        <name evidence="19" type="ORF">BGZ80_004445</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Exonucleolytic cleavage of poly(A) to 5'-AMP.</text>
            <dbReference type="EC" id="3.1.13.4"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the CAF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.13.4" evidence="5"/>
    <dbReference type="EMBL" id="JAAAID010002269">
        <property type="protein sequence ID" value="KAG0007613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SW23"/>
    <dbReference type="OrthoDB" id="1164111at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030014">
        <property type="term" value="C:CCR4-NOT complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004535">
        <property type="term" value="F:poly(A)-specific ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031047">
        <property type="term" value="P:regulatory ncRNA-mediated gene silencing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000005">
        <property type="entry name" value="CCR4-NOT transcription complex subunit 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039637">
        <property type="entry name" value="CNOT7/CNOT8/Pop2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006941">
        <property type="entry name" value="RNase_CAF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10797">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04857">
        <property type="entry name" value="CAF1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0540">Nuclease</keyword>
    <keyword evidence="17" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0678">Repressor</keyword>
    <keyword evidence="13" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="15" id="KW-0943">RNA-mediated gene silencing</keyword>
    <keyword evidence="16" id="KW-0804">Transcription</keyword>
    <keyword evidence="14" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="12" id="KW-0810">Translation regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="288"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAG0007613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="309" mass="34667" checksum="59108007210505AF" modified="2023-09-13" version="1">MPSPNERAIIREVWAENLEQEMALLRDLVDQYPYLAMDTEFPGVVARPIGNFRTSADYHYQTLRCNVDLLKMIQLGVTFADEDGNVPKDACTWQFNFKFSLAEDMYAQDSIDLLTKSGINFQKHEDYGIDVHHFGELLISSGFVLLDEVKWISFHSGYDFGYLLKILTCSPLPAEEGDFFDLLRTYFPCIYDIKYLMKSCKNLKGGLQELANDLQVVRIGAQHQAGSDSLLTCSTFFKMRQIFFEDKIDDAKYLGYLYGLGSAVGSTATQPNSIATFNSAAGNDSPLITNQSAAPNGKPNSFQKASINI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWV9</accession>
    <name>A0A9P6SWV9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">TATA element modulatory factor 1 TATA binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_003112</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001803">
        <property type="protein sequence ID" value="KAG0008743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWV9"/>
    <dbReference type="OrthoDB" id="74178at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052602">
        <property type="entry name" value="Growth_transcription_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022092">
        <property type="entry name" value="TMF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022091">
        <property type="entry name" value="TMF_TATA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46515:SF1">
        <property type="entry name" value="TATA ELEMENT MODULATORY FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46515">
        <property type="entry name" value="TATA ELEMENT MODULATORY FACTOR TMF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12329">
        <property type="entry name" value="TMF_DNA_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12325">
        <property type="entry name" value="TMF_TATA_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TATA element modulatory factor 1 TATA binding" evidence="6">
        <location>
            <begin position="1034"/>
            <end position="1141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="50"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="830"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="951"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="618"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="1040"/>
            <end position="1088"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="1113"/>
            <end position="1151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="60"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="95"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="123"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="133"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="173"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="221"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="245"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="262"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="287"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="322"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="954"/>
            <end position="972"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0008743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1154" mass="126664" checksum="27D0A721986CACF5" modified="2023-09-13" version="1">MSNFFGTSSSGSGANSNKSSSSGSGGGGWGTFLKQGLSTIESKLDTVLDINVPIPGGSSGILTSFSPHASVLPSSDTPKDTPPKRKPPHQVPSTSHDDSLHQEEDTRTQDSVVDLSKNDPKRSSISIKNPTIKNKDSERDLRKSANATSIRGSMDEEASGMITTIPGVKRMMTPPVSGTGVGTTTPSASASSALSATAATAAANRERLEQRMRGIFKKSAESPSTTPTPSMAAARSPAGSSSPSVRHSTSLEPEIQSQENEGAGRGDESVEKDTKPIVAEIVVAKTSQEEIRQELKETVLAPPDSDSAKEPENCDSLQDLKNNGDGEKVEPANHLHPDSIQEPEIESTDQVNKSTVMHEDVSPSEPLVEAVESNINRTSLEEPETTAKEELEPELEQDDRKSDNVIELDRVDNAPDLASLDNQQIATTLSETPIECPYTPTSNTEPQLVSAVQDDSIVTVQISGQDDIASKVDSKEDASVSHENPLKKVLEQREEQLLKVMQEQSSLLEKLRDLEDAKAADETLKNTKISGLEMIIETQKKELEAARGSNLTSQPKSIQKTLEEQRALLEDKDEQIRGLLAEGEVLSKKEFKNLTAIKALRTKNIEAEKLQMGTQKKLDRAVSDYADAQAKLSKLSDENKQLNDAIKSLHDINQRQNKQMSKMEAELVQLRDDKANLQLGVDRLKQELSEARKVSAELSNQAHAAALEREVKLNEDLNNEIDALKAQHTAVESNLRQDIQELRVSLSNREELAGEKEDQLLMEIRNLQARLEQTDNDSYELQEVLDEARRPLLRQIEVLQNQQGIASRNWDRVEKSLTRRVAEAEEEMAKAQERERAARDKLDEMKSQSTSHEARLEALRVADTQLRAEVNAAKRALKEKEEETRQAQAELARERVNRERAIEEAKDDAERKLRLQQQTEIDKLKQQIQQLQQRQGASDNQSEIHLSTVDSMMRRSSSTGTSSSSPLLSGGPLVMGGPKAATQISNLSAGFDSITSPTSLDGMSPILSRSNSSQTMSGTGAASMGLMGLGSGATGQAVAIERLNTMVRQLEGQVTFLSEQVRTANKNKDELSDELVRVTVELEELQTQASRAPSLEQELTLLQERHKAALEMLGERTEEVQELKADLADVKEALRDQISELLSQLEQSRRANKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWW9</accession>
    <name>A0A9P6SWW9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Chromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_002786</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001700">
        <property type="protein sequence ID" value="KAG0009066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWW9"/>
    <dbReference type="OrthoDB" id="433924at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000792">
        <property type="term" value="C:heterochromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd00024">
        <property type="entry name" value="CD_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008251">
        <property type="entry name" value="Chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023779">
        <property type="entry name" value="Chromodomain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051219">
        <property type="entry name" value="Heterochromatin_chromo-domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22812">
        <property type="entry name" value="CHROMOBOX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01393">
        <property type="entry name" value="Chromo_shadow"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00300">
        <property type="entry name" value="ChSh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00598">
        <property type="entry name" value="CHROMO_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromo" evidence="4">
        <location>
            <begin position="54"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="107"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="22"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="45"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="107"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="121"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="163"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="219"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="245"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0009066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="326" mass="35978" checksum="2A601F0B350EFF98" modified="2023-09-13" version="1">MSEKIDVKDKQHASGTKRAADDSELSEVDSEIDDDVSNDGKDGEDALEDEGEEYEVERVVGHKRERGVLSFLLKWQGYDDADNTWETSDNLSCGELINEYWERYEKAGGKKSDLKGSDSKPQISKRGSGSTKSTASPSKQSTSAKQSSPVKQSTTAKQSTPVKQSTTAKQQTAAKQQTSSKSAAQKQETPTKSSASATSKKNVRDDSSSMGSPAKKQKVNTSTHGTTHPTSEAEDDFVSAQDEAGSGDDDEDWESANGGWMPPKSWTSWDEHLDHVQTVERTKRSMIIHLKWKNGKDTEHPIEEAHVKCPQTLIRFYESHLKFTQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SX53</accession>
    <name>A0A9P6SX53_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">SPT3 Dosage dependent suppressor of Ty-induced promoter mutations-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">SPT23_2</name>
        <name evidence="5" type="ORF">BGZ80_002374</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001582">
        <property type="protein sequence ID" value="KAG0009458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SX53"/>
    <dbReference type="OrthoDB" id="366390at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00102">
        <property type="entry name" value="IPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002909">
        <property type="entry name" value="IPT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23335">
        <property type="entry name" value="CALMODULIN-BINDING TRANSCRIPTION ACTIVATOR CAMTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23335:SF1">
        <property type="entry name" value="CALMODULIN-BINDING TRANSCRIPTION ACTIVATOR, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01833">
        <property type="entry name" value="TIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IPT/TIG" evidence="4">
        <location>
            <begin position="338"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="2">
        <location>
            <begin position="558"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="214"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="639"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="214"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="661"/>
            <end position="685"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0009458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1058" mass="116214" checksum="E0057F60A5C744F8" modified="2023-09-13" version="1">MSAYSLEARIIQKKDQLEGLSASGAIIPAPIVDEVRTGQQFLIKLQFVKNGLDHTSMFPSLRVGRRVAINTISDPSSDPEPLTLEISMHLAKSGQTKKSACAKCCHKYGPFSPILVLLDPLSPSVTDPTTYAHIDTTTGSATLLAKVICSSTDHGERGNKDRYIFEFKLKRTSSMPSNAADISSSPPIEGIEEEGETLSTCFTHAIMCSGHHKAKRAYPHQRPTKINKEGPTPKTKIVKRHRSDPNINTPLDAMESQAENLMNAKAMARDLDFQNPMAFLSDHLSMTPITETFAERPDSLQSNSISTDSQSFLSSTHILSDMMQPQQQSQQQSQQSYPKITEIRPNHGPIRKRIDVVLRGLSFRDGMIPYFGCFQAQEISVETSNLIICKAPESPLPGPVSITIYDSTGNCFSDLGQFTYTDDSETELLILQLQLRLAHRALEYMHAKATGQRGNVNDILRNIPELATSPGSGSVLMMEKQCSDSTLGADTPLLSQSMVEQGIIDTLDLLGLLPKDIDISLQLEDGSNLLHLSTILGFNKMAIRLVEEGCDFEAQDIYSLTPLMYAVLKGNETMVKTLVMAGASLTGARTPEEYYARLPRGVGSTQVIHYYLSISCTRFSATPFTVGDTVKKKKKTEIGDTEGSYGSYGEECTTADDTDESQTVKAISPRSQSPITTSLPSTQPTPVGLGLEGLPSKEYDIVTELEGGIRDMHVNHNAPPLDQRNHHNTPPLDQQSLPQFRVVQSDGSFLINTGVIRRADVLNASGQGTEQHFESVNQESGYHTGICPGVQAHLDTLHSAILPSQRVRMHVSFKLPPNSFAPMMTKPLSNSSMPMQLLRTGDSFTIELRLTTPSGNQIPMPREFVGIKFPPEMIKRTTGKPAPILENMTYALRVSIRLGEIDVGASSSSNPEPVDTHELSGVALTGSCRSCSKLIHEHKKPPPSRIPSSEPLMYPILQFYVHGKTDPYRIIPSASVVSNPGVVELRNGVCEVKAKVNCSSLHHLQRAMAKRARTRALPELRDPGYVFKFELVHPSLRTVVAQYETRPISFQSYPRGGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SY10</accession>
    <name>A0A9P6SY10_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_001057</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001235">
        <property type="protein sequence ID" value="KAG0010948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SY10"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="366"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="661"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="48"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="198"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="253"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="379"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="429"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="491"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="518"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="556"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="572"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="597"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="663"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="704"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="728"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="751"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0010948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="762" mass="84029" checksum="16DF1483245F6A5D" modified="2023-09-13" version="1" fragment="single">HSFYAEYTGSVATKATSTNQFNVSGAIVEVPKTTTTTATSTILVTSTAHTTTTSATASATQTNQGSGGISGGALGGIIGGAVAFLLLVALIFFCRHRRNARENSQHTRLEDSKESYSESRSGPPSIGTPGRTSGPGPHPSHDEYNVSSRSMHPMQQMNGDKNPFEGSEERIAPPQMMYGGATPLSPRVQHQPQLSPRQYQQQQQYQQQQQYQQQQYQQQQQPYGMPGMPHQQSSFQNRRTSLESEAESAYDPNRMMNRNNSMNVGGSAPVQRNNSNPMMRGGSQTSGRSPLMNGANMSPMNPFQDRELMAAAAGATIVQQHQSPLLRSASPRVREIEMQPLDVQQHQYEQLQRLQQQKQLQQQQQQQQQQQQEQERQAPATSAPVSPTSVAHQFNPTLYDDKAEVDEDGVPVYNGYRDTIFGHYQPQGNEDDEDEEETPTPIVPPSTLAAKIDNDANATEGNVGGATGVQRKKSVKFTVPNSESIEIDVSAVSSTRQENTKAQAQAQHSDQSDMSHSEDDDDEEEEEEEEEEEEEEEEEEDYDEDEDDIKLRLMESEVPSPSSSSSRPFVDTTPSASPMSFHQNQSPNTFSPTQAYSPSTSQFQRQQQQQQQQQLSPTLQSNNNYVAPPPPAPLPVTSLQDTPSLGDGFYEDVLAAVEKNAMTLPSTTAQNTTSHPQPKHLQAIHSEREVFGAPSPRMKPAAPSNPQQSINTSPPQQPVNAKPVLSPRSAARPTAAQQRQQQQQQGRQDYSDDDEFYEASLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYA3</accession>
    <name>A0A9P6SYA3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosome production factor 2 homolog</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Ribosome biogenesis protein RPF2 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">RPF2</name>
        <name evidence="7" type="ORF">BGZ80_000886</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Nucleus</location>
            <location evidence="1 4">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the RPF2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001199">
        <property type="protein sequence ID" value="KAG0011158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYA3"/>
    <dbReference type="OrthoDB" id="407658at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
        <property type="term" value="P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007109">
        <property type="entry name" value="Brix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039770">
        <property type="entry name" value="Rpf2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12728">
        <property type="entry name" value="BRIX DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12728:SF0">
        <property type="entry name" value="RIBOSOME PRODUCTION FACTOR 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04427">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00879">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50833">
        <property type="entry name" value="BRIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Brix" evidence="6">
        <location>
            <begin position="28"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="281"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="291"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0011158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="314" mass="36039" checksum="4E5C9E1DFECC3C3D" modified="2023-09-13" version="1">MLRTITPRNARVKRVLKNREAKTEENIKTAIFIRGSQTSQIVNDALSDLYMLKKPYAINFTKKNQIHPFEDQSNLQFFSQKNDASLFVIGTHSKKRPHTLTFARMFDHQLLDMIEVSIEQGTAMKDFKTPKSAIGMKPCFMFNGDMWDQNPSYIMFKSMLLDFYHGQTVDKVALAGLEYVISVTAGPMTSEGKPGKIYLRTYTISLKRSGVKLPRIELVEMGPSLDMTFGRIMEAKPDVWKQSLRVPKELKPKKKKNITKDEMGDTVGRIHLGKQDFDKIQTRKMKGLKKRTAEDKDDASTDKKQRVDDSDDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYW6</accession>
    <name>A0A9P6SYW6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_011637</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000961">
        <property type="protein sequence ID" value="KAG0012595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYW6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0012595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="148" mass="16980" checksum="7ED7E06B15151C78" modified="2023-09-13" version="1" fragment="single">MIPQPSSDIAGESQGHSRQGSVLFDDQSRIVESGTIYELQLVVRDMEDDTLSFEYTDHLHGTVDGGGPLVSCETIDSILYLKYDDKYLYATNEKEIGLKVDVPERHERLRFLMSDNNTFRISKWDQEVFATLEWIKCSYGAVWFEEGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZ17</accession>
    <name>A0A9P6SZ17_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4110 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_011431</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000919">
        <property type="protein sequence ID" value="KAG0012902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZ17"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025183">
        <property type="entry name" value="DUF4110"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052588">
        <property type="entry name" value="Kelch_domain_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46063">
        <property type="entry name" value="KELCH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46063:SF1">
        <property type="entry name" value="KELCH DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13422">
        <property type="entry name" value="DUF4110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4110" evidence="2">
        <location>
            <begin position="752"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="352"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="586"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="352"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="383"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="395"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="451"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="468"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="517"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="591"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="645"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="670"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="713"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="854"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0012902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="854" mass="96467" checksum="FEC74676446396C8" modified="2023-09-13" version="1" fragment="single">KKKKSKEHKAKVAEKQDRKQSKKEKKAKAKNVEEQEEDIETILANFKKEQEEKVKIIEEIWSGPPSRRANATLTANPLNQNELIFFGGEFFDGARCAFYNDLYRYNIEKDEWRRITSPNSPGPRSSHQIVITSAGTLFLFGGEFASPNETQFFHYKDFWSMDMKTNAWEKLDVKPKPTARSGHRMALWKHMIVMFGGFYDNYVDTRYYDDLWVFDTLEYKWTKVELPDQMIRPSARSGFSFIPCNDGVILYGGYCKEYTKGQRPKGVVHTDTWLLKMNADPKLIRWEKKKKSGSAPTPRSGCAMAPYKNRAVLFGGVYDDDVNEETLESTFYNELYTYQIDSGRWFPMNLKRPKTAKKKKPKKNKQGGESGAGRAGDGDDDEGSGKREKMKWEESTDDEFDYGDFEDSENEGEGALGTGEASTTENQGHPKLLKEEESAFGASTPQEGDETTDKGDNDDLEKQPTKEALAAAALAAAGILPKSAQTPEPTTEPEATKKGTSKSGRQSGRSKENTNNGDDDDEAEEEPLMPCPRYNPMLAVQKSTLFIFGGILEVRDREYTLDDFFSLNLDKMTEYVCLRESEFESQLWLGEESDDEDEDDDEDGDDDDDEDEDGEDEEEEDEEEEEEKEEVIAESSKRGKKSKKEGKEKKVEKVEKVEKEEKEGKEKKDKKEKKEKKEKKEKKEKKDKATAESTPSAGAIDPNTASTESEVKPGATGTPAEGGEATESAPEVVPSQLSGVDLAARLAMTEEEAACTPTIGETLREFYGRTTEFWVLKAFEDSTKTGKALRHDGFLLAEAKFNEWQPILAQMAQMRLDAGLDEDDDDEASRMGGRRGGVLKMGEVYNKLMSRNRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZE4</accession>
    <name>A0A9P6SZE4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">CD9 antigen</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">MRP-1_2</name>
        <name evidence="11" type="ORF">BGZ80_011273</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000888">
        <property type="protein sequence ID" value="KAG0013130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZE4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042626">
        <property type="term" value="F:ATPase-coupled transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000163">
        <property type="entry name" value="Multidrug resistance-associated protein member 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF443">
        <property type="entry name" value="MULTIDRUG-RESISTANCE LIKE PROTEIN 1, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="115"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0013130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="381" mass="42401" checksum="483342690D49E8A7" modified="2023-09-13" version="1" fragment="single">NEKRSDDIVQITNLFFLTNRWLTIRIQTLCATTVFLAAALAVLNVDKLDPSLVGLALSYALNLTNVIAILVRTLGEVENQFVSVERILEYIEKPVEAPAKTAVTVSRDWPSQGKIVFKDFSARYREGLDLCIKDASFTIEPQEKIGVVGRTGAGKSSLTLALFRIIEAADSYWARSSDPSASGHHITDEYSAHINGGSIEIDGVDISTLGLQDLRKHLAIIPQDPTLFAGSVRYNLDPFHDLKDIDLWEALDRAHLKDYISSLPGGLSFEVSQNGENFSLGQRSLLCLARALLRRSKVLVLDEATASVDVETDELIQKTIRKEFRDRTVLTIAHRIKTVMDSSKILVLEKGQVKEFDTPSELIKKKEDSLFYRLAEQAGEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZE5</accession>
    <name>A0A9P6SZE5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Fibronectin type-III domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_011709</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000977">
        <property type="protein sequence ID" value="KAG0012477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZE5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031032">
        <property type="term" value="P:actomyosin structure organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050839">
        <property type="entry name" value="Rho-assoc_Ser/Thr_Kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22988:SF71">
        <property type="entry name" value="CITRON RHO-INTERACTING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22988">
        <property type="entry name" value="MYOTONIC DYSTROPHY S/T KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="7">
        <location>
            <begin position="114"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="230"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="350"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="546"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="604"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="765"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="799"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="915"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="950"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="494"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="242"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="558"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="643"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="693"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="723"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="765"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="802"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="836"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="920"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="968"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="983"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1002"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0012477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1002" mass="110191" checksum="135E9C7D37C2C0A4" modified="2023-09-13" version="1" fragment="single">MCLSNVLVYYTVPFSFTSPFATGVAFGLMVSLIHGLNLKGVILAMTMYMLKPYIERQTLIAALNPPTVPSIVFLAPLASFCSAFGVLWLLYDLFGYLHASTDDLRDFFGITLPAPSIVTLKDVKDRSITLNWQCSSQATISKHLIEIDGVIIGESGKQETSVVIQGLYPDNTYRIRLWAITTRNWKTPSDYIVVRTLASVPVELELSSAENIRKESELIKKLIKESEELQQLSKEQGQNDNADTKSQESKREKSDVASLSDITTEDSKSIALASTNVSFNAALHPTPSLHGGIPSSKSTVTDEQISALRVELEGKEASHALLIQQLSDLEKQYKQQEDQLKGEITTLREQQKLDDEPRQQAKIKQKELEESLRESEAHKSKLEKEHRIEVEKRQKMMTQLGAKQKRLESLQQTLHQCEERLRSEKLSHQRQIQELEAALVQRSEDVKTAESSLKALQDSQKDLCSTIESKELELQKLQATINSPKGYLSWEQKSKDLDIQCAQLTLQLDQCKAENLQLQERLAEVTKNVSKVKLARETRRAQVEARKASRISVAEATAPQTHPDNQIQDHASNWANSGWNSNLGTQLLSGLFQDNISENDVRASPVRKITGPPPGLSAKTNVPEANKAKESNAPGYGRDRKNSGSQGSPTISRSPSRPNSQVGGPSKTQRYSGLRPRSPSTTGLVSPFLDEPSGTSSGRFPNSNGSPILTPDLGTDRNETRSRTSSISSLPGFQSPLFDPSFVFSTHAQSQQDSAMTGQIFQNTAHSRQSGHVRSQQPQGHGLSPRARFQVAGQLNSTPIVQGQPQWGGQNPPRAKPNPMSTNFGGRSPMPDLDSKGSQNKSPAQPLNYHRFFGPPSSIDMSGMLSENGSVSDHQLDEQNVIKSMFESPDTLDLRHHLRTVGSHSSLTTQSKILPSHLRSISTPGTSSPLSSPITSTLLPFQSSPTWDIKPIARPGSLNRMNSQAEGSSSSLNISDSSSPTSPQVMPFSQTGPGFGRKTPSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T002</accession>
    <name>A0A9P6T002_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="21">Lysosomal dipeptide transporter MFSD1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="22">Major facilitator superfamily domain-containing protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="27" type="ORF">BGZ80_010471</name>
    </gene>
    <organism evidence="27 28">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="27" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="27">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="23">Lysosomal dipeptide uniporter that selectively exports lysine, arginine or histidine-containing dipeptides with a net positive charge from the lysosome lumen into the cytosol. Could play a role in a specific type of protein O-glycosylation indirectly regulating macrophages migration and tissue invasion. Also essential for liver homeostasis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>L-alanyl-L-lysine(out) = L-alanyl-L-lysine(in)</text>
            <dbReference type="Rhea" id="RHEA:79415"/>
            <dbReference type="ChEBI" id="CHEBI:192470"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-alpha-aminoacyl-L-arginine(out) = L-alpha-aminoacyl-L-arginine(in)</text>
            <dbReference type="Rhea" id="RHEA:79367"/>
            <dbReference type="ChEBI" id="CHEBI:229968"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-alpha-aminoacyl-L-histidine(out) = L-alpha-aminoacyl-L-histidine(in)</text>
            <dbReference type="Rhea" id="RHEA:79375"/>
            <dbReference type="ChEBI" id="CHEBI:229967"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-alpha-aminoacyl-L-lysine(out) = L-alpha-aminoacyl-L-lysine(in)</text>
            <dbReference type="Rhea" id="RHEA:79383"/>
            <dbReference type="ChEBI" id="CHEBI:229966"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>L-arginyl-L-alpha-amino acid(out) = L-arginyl-L-alpha-amino acid(in)</text>
            <dbReference type="Rhea" id="RHEA:79371"/>
            <dbReference type="ChEBI" id="CHEBI:84315"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>L-arginyl-glycine(out) = L-arginyl-glycine(in)</text>
            <dbReference type="Rhea" id="RHEA:79391"/>
            <dbReference type="ChEBI" id="CHEBI:229955"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-aspartyl-L-lysine(out) = L-aspartyl-L-lysine(in)</text>
            <dbReference type="Rhea" id="RHEA:79411"/>
            <dbReference type="ChEBI" id="CHEBI:229953"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>L-histidyl-L-alpha-amino acid(out) = L-histidyl-L-alpha-amino acid(in)</text>
            <dbReference type="Rhea" id="RHEA:79379"/>
            <dbReference type="ChEBI" id="CHEBI:229964"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-histidyl-glycine(out) = L-histidyl-glycine(in)</text>
            <dbReference type="Rhea" id="RHEA:79395"/>
            <dbReference type="ChEBI" id="CHEBI:229957"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-lysyl-L-alanine(out) = L-lysyl-L-alanine(in)</text>
            <dbReference type="Rhea" id="RHEA:79399"/>
            <dbReference type="ChEBI" id="CHEBI:229954"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-lysyl-L-alpha-amino acid(out) = L-lysyl-L-alpha-amino acid(in)</text>
            <dbReference type="Rhea" id="RHEA:79387"/>
            <dbReference type="ChEBI" id="CHEBI:229965"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>L-lysyl-L-lysine(out) = L-lysyl-L-lysine(in)</text>
            <dbReference type="Rhea" id="RHEA:79403"/>
            <dbReference type="ChEBI" id="CHEBI:229956"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>L-lysyl-glycine(out) = L-lysyl-glycine(in)</text>
            <dbReference type="Rhea" id="RHEA:79407"/>
            <dbReference type="ChEBI" id="CHEBI:191202"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="24">Homodimer. Interacts with lysosomal protein GLMP (via lumenal domain); the interaction starts while both proteins are still in the endoplasmic reticulum and is required for stabilization of MFSD1 in lysosomes but has no direct effect on its targeting to lysosomes or transporter activity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Lysosome membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="27">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000730">
        <property type="protein sequence ID" value="KAG0014405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T002"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052187">
        <property type="entry name" value="MFSD1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23512">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23512:SF3">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0458">Lysosome</keyword>
    <keyword evidence="6 26" id="KW-0472">Membrane</keyword>
    <keyword evidence="28" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 26" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 26" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="26">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="26">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="26">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="26">
        <location>
            <begin position="133"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="26">
        <location>
            <begin position="161"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="26">
        <location>
            <begin position="197"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="25">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="25">
        <location>
            <begin position="8"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00044891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00044898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00044899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00044900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00044903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00044912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00044919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00044924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00044985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00045018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="ARBA" id="ARBA00045709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="ARBA" id="ARBA00046376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="26">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="EMBL" id="KAG0014405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="28">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="365" mass="40845" checksum="F04526B2672BE547" modified="2023-09-13" version="1">MTLSSAALEEEDEAEKENEMAEDDQMRYSEIFTLKTTFWILSLCCISLYGAVVPFIHVSSDFLQKKWYLNDPTKAGAVMSIPDLVSSIGSPLCGYIVDRFGGRARYIPLSAILLIWAHAQLGFTMVIPVPAMLVLGLAYSLFASVLWPCIPFLVKDHQLGTAYGLVTIALNISLTFFPMLVASILDSTNGSYVHVEGLFVCLAIIGLLFSILLNVLDYRQGGHLQLTEGCSSPQSQDHDEDEVHEQRELYSRQDYYNPREPGFEYRRKRRYSQNIFAEEDPDIEDVQNMVTTKPVGEGIIAVIPHRRRHSMAGFAGQTERARLSYYAHHAQGAPSLNEIAGSMSQEPPSYLSTRIASTALDRMEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0A4</accession>
    <name>A0A9P6T0A4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cyclin-dependent kinase 1</fullName>
            <ecNumber evidence="2">2.7.11.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">CDC28</name>
        <name evidence="15" type="ORF">BGZ80_010065</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.22" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010000661">
        <property type="protein sequence ID" value="KAG0015081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0A4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000307">
        <property type="term" value="C:cyclin-dependent protein kinase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030332">
        <property type="term" value="F:cyclin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000082">
        <property type="term" value="P:G1/S transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010389">
        <property type="term" value="P:regulation of G2/M transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07835">
        <property type="entry name" value="STKc_CDK1_CdkB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000281">
        <property type="entry name" value="Cyclin-dependent kinase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000027">
        <property type="entry name" value="Putative Cyclin-dependent kinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF254">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 12 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 13" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="14">
        <location>
            <begin position="4"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00039266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0015081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="310" mass="36077" checksum="03BD335738982A98" modified="2023-09-13" version="1">MEAYQKLEKIGEGTYGVVYKATERATGRVVALKKIRLENEDEGVPSTAIREISLLKELRHDHVVQLLDIIHDENRLYLVFEFLDLDLKRYMDTLPVTTNSGLPLDQVKEYLYQLVRGVEYCHARRILHRDLKPQNLLIDETRNLKLADFGLARAFAIPLRPYTHEVVTLWYRAPEILMGSRHYSTAVDIWSIGCIFAEMVQKKPLFPGDSEIDELFRIFRLRGTPNEELWPGITQLKDWKPSFPQWRRQPLENALPTLCPEGLDLLGQMIEYDPARRISAKRALLHPYFDSIRRGQQNGSTQARIEIRSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0B6</accession>
    <name>A0A9P6T0B6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ferric reductase NAD binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_010482</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000733">
        <property type="protein sequence ID" value="KAG0014369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0B6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043020">
        <property type="term" value="C:NADPH oxidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016175">
        <property type="term" value="F:superoxide-generating NAD(P)H oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042554">
        <property type="term" value="P:superoxide anion generation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.80:FF:000004">
        <property type="entry name" value="NADPH oxidase isoform 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000778">
        <property type="entry name" value="Cyt_b245_heavy_chain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050369">
        <property type="entry name" value="RBOH/FRE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972">
        <property type="entry name" value="NADPH OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972:SF153">
        <property type="entry name" value="SUPEROXIDE-GENERATING NADPH OXIDASE HEAVY CHAIN SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00466">
        <property type="entry name" value="GP91PHOX"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Ferric reductase NAD binding" evidence="9">
        <location>
            <begin position="16"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0014369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="229" mass="26208" checksum="A147BBA990469FD7" modified="2023-09-13" version="1">MIDGPFGAASEDVFKFEVTVLVGAGIGVTPFASVLKSIWYRVNYPTKATKLHKVYFFWICRDKESFEWFQSLLLALESQDLNQFIEIHTFLTGRLRHSEVGNLMINDQGAFADTVTGLRARTRFGRPNLDAEFERIRGHHEDTDVGVFFCGPKKMGKQLHACCAKFSQGTTQFVWHKACELEGLVRKRQTVEDKELTYRFVDFSPVKHECLVFSHKSANLSLKSLNNLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0D0</accession>
    <name>A0A9P6T0D0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Tafazzin family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BGZ80_009956</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a cardiolipin + a 1-acyl-sn-glycero-3-phosphocholine</text>
            <dbReference type="Rhea" id="RHEA:33731"/>
            <dbReference type="ChEBI" id="CHEBI:57643"/>
            <dbReference type="ChEBI" id="CHEBI:58168"/>
            <dbReference type="ChEBI" id="CHEBI:62237"/>
            <dbReference type="ChEBI" id="CHEBI:64743"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:33732"/>
        </physiologicalReaction>
        <physiologicalReaction direction="right-to-left" evidence="11">
            <dbReference type="Rhea" id="RHEA:33733"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Intermembrane side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Mitochondrion outer membrane</location>
            <topology evidence="10">Peripheral membrane protein</topology>
            <orientation evidence="10">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the taffazin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000644">
        <property type="protein sequence ID" value="KAG0015260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0D0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047184">
        <property type="term" value="F:1-acylglycerophosphocholine O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035965">
        <property type="term" value="P:cardiolipin acyl-chain remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007007">
        <property type="term" value="P:inner mitochondrial membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07989">
        <property type="entry name" value="LPLAT_AGPAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000872">
        <property type="entry name" value="Tafazzin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12497:SF0">
        <property type="entry name" value="TAFAZZIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12497">
        <property type="entry name" value="TAZ PROTEIN TAFAZZIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00979">
        <property type="entry name" value="TAFAZZIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69593">
        <property type="entry name" value="Glycerol-3-phosphate (1)-acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="4" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phospholipid/glycerol acyltransferase" evidence="13">
        <location>
            <begin position="1"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU365062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0015260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="251" mass="29042" checksum="A9FA926EB86A34DA" modified="2023-09-13" version="1" fragment="single">ADDPLLWGALPWRCYKDPTKTIRYALGAQELCYPNKPVAAFFRFGQIVPIIRGNGIYQPAIDKSIDLLRTGKWVHIFPEGKINQTDQLIRLKWGVGRILMEYGGPTLAMGGKPMDQIEMPIVIPIYHLGMEDILRLYPDNSSPVFPKLGMPLTIVFGEPIDFTSLMQEYKEGKIQEIEARVKITERVFDAMEELRKATLKLHKEQEDRAKQDRIKKGYWWWIQPVGWGWWSSSDVKLEVTHRDTSVKIEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0E3</accession>
    <name>A0A9P6T0E3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_009749</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000610">
        <property type="protein sequence ID" value="KAG0015620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0E3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051580">
        <property type="entry name" value="ZnF-Chromatin_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23057">
        <property type="entry name" value="JUXTAPOSED WITH ANOTHER ZINC FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23057:SF0">
        <property type="entry name" value="JUXTAPOSED WITH ANOTHER ZINC FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="413"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="455"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="145"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="315"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="552"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="651"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="165"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="315"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="333"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0015620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="698" mass="72834" checksum="354E241C56320E19" modified="2023-09-13" version="1">MPAAIPTPSINITATSSSSSSSSSTPSRQYASGTPVASGSLTHGFSTLSSSALGSSPFSAEALAAATALRRPSLVLSVGSFHSAQLRRPSFLFPYGQSPQQFERGGDVYQRDLEANYCTNFSCCGLTLGDLHALLQHYEESHVRFEEEDDNGHPVPAGFVDEDGWSTSSESASDSPHTHQGHQSKGPSGSTLSANAAAAATVAALTASHQQQQQQQEQKLTPLGFLNARKKSNGVSLSDIYSEDSGFSTADDVVSAFPNSILRTAAQAEFTNLASKKRDLAAYSTSFDTHSPMAKKISNFQNMTLSSATATFNGSNNISGNETLRNGTQSNIGGSSSTGATSSTAAKTQEELLGSVTDYLQLAMKQGLLPDCGEVGSPSYLLAAEDLIKKREELVNIIESIGKTGTSNADKPYRCQVSGCDKAYKNPNGLKYHNQHGHCSASGLADSEGPESKPYVCTFMDCGKRYKNLNGLKYHIEHSHPNLTAALKAHQAGLTSHPLLVNGVFANNQAAALTIAAALSAVEASPMMMAAINAITASAANSNNAAINNTNVINRLSPPSDHTPDSSPSSSPALKASATTATTNAQSATIAAPVPTVFINNVNSNLNTNLTAYRDGNAFSTDVTPMTSPVLSRAALPQLNLLSILTSGLATPSSLSPTTSAPPKSPTGGSQVSTLTAALAAVTVEQQRQQQQQQRPVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0M2</accession>
    <name>A0A9P6T0M2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Glucose-6-phosphate isomerase</fullName>
            <ecNumber evidence="3 9">5.3.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_009453</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">In the cytoplasm, catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:11816"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:58225"/>
            <dbReference type="EC" id="5.3.1.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 9">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the GPI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.9" evidence="3 9"/>
    <dbReference type="EMBL" id="JAAAID010000569">
        <property type="protein sequence ID" value="KAG0016059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0M2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004347">
        <property type="term" value="F:glucose-6-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048029">
        <property type="term" value="F:monosaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051156">
        <property type="term" value="P:glucose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05015">
        <property type="entry name" value="SIS_PGI_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05016">
        <property type="entry name" value="SIS_PGI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1390.10:FF:000001">
        <property type="entry name" value="Glucose-6-phosphate isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10490:FF:000004">
        <property type="entry name" value="Glucose-6-phosphate isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10490">
        <property type="entry name" value="Glucose-6-phosphate isomerase like protein, domain 1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00473">
        <property type="entry name" value="G6P_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001672">
        <property type="entry name" value="G6P_Isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023096">
        <property type="entry name" value="G6P_Isomerase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018189">
        <property type="entry name" value="Phosphoglucose_isomerase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035476">
        <property type="entry name" value="SIS_PGI_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035482">
        <property type="entry name" value="SIS_PGI_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11469">
        <property type="entry name" value="GLUCOSE-6-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11469:SF1">
        <property type="entry name" value="GLUCOSE-6-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00342">
        <property type="entry name" value="PGI"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00662">
        <property type="entry name" value="G6PISOMERASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SIS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00174">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51463">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="5 9" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="6 9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0016059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="533" mass="59742" checksum="7F4A1612771DD6FB" modified="2023-09-13" version="1">MVLANKLHAWNALQAHHDKDADKIVMKDLFAQNPERFHQFSRHFQGPTTKSSILLDFSKNIITEETFKHLIELAREAGVEDMRNKMFSGEPINFTENRSVLHVALRNVSNTPIYSEGKDVMPEVNAVLDHMKSFTESVRSGEWKGYTGLPIKDVVNIGIGGSDLGPVMVTEALKPYATEGGLKVHFVSNIDGTHIAEVFKVVKPETTLFIVASKTFTTQETITNATTAKNWFLEHAKEHAHVAKHFVALSTNTEAVSKFGIDPANMFQFWVWELLTGAHEMDQHFVNTPLDQNLPVILGVLGIWYINFFDAQVHAILPYDQYMHRFPAYFQQGDMESNGKYRNRDGEAIPYGSGPWVVGEPGTNGQHAFYQLIHQGTRITPCDFLAPVETHNPLAGHHDILLSNFFAQTEALMAGKDEEAVLKELQQDKSLSAAQVQQIAPHKIFRGNKPTNSIMFQKLTPGTLGGLIAMYEHKIFVQGVIWNINSFDQWGVELGKQLAKKILPELATGTGEVKSHDSSTNGLINFYKQHKRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0P8</accession>
    <name>A0A9P6T0P8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_009494</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000575">
        <property type="protein sequence ID" value="KAG0016005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0P8"/>
    <dbReference type="OrthoDB" id="2431077at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0016005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="190" mass="21449" checksum="E92AB2EB4129B915" modified="2023-09-13" version="1">MTTTLVRRCVSMFFMEAGLWAGIDWFKRGSGNNEDTFINNLVKPLLSAAFGRLAGCTFRWSRDPLRSGKRKDPDARLLLPDYQVSFGARSIFLAEFKTAVASRKEMENDFIKLTCMGKKAVDALYKDGFHASVVLMHGKGVDIEVFELRLRAEAVYFLQCLGKFQLVTNPQEFPLLLCLGPLISAQVRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T157</accession>
    <name>A0A9P6T157_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008480</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000460">
        <property type="protein sequence ID" value="KAG0017263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T157"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0017263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="421" mass="46254" checksum="AF3AA8DE278ECF2E" modified="2023-09-13" version="1">MRTVQDPNTYGYPRKLGFGQDSIYQFGSIVANNMTGAFKSLLTRIPLNSPNGTVFSPPTNLPVYEIDNFRVISINPGGTASNYTFTYELQPISSGGNSGVWGYDPPRWMSLDPNTIGAFNPDSSTGSVKITEPFEFWPIHNRPTDPITYVSIGVSVFVLLVIVIIVWRNWRHVVKFRTQIWPSWKRKIKTKIIDFASRIDDGDDGSKISDADGSLESGTRYEKSDPTINKIEEMPMQLIDAEEGHKILVTPDMDLSDLDDVITTVAASPSPAVVDVNVEYMMAVNLDTHPRPAIVTTLSDDSILGNGRLDNSSENNLSLLRPDLTVSLAPLSSVSRNIDVLTEYHGQYTTPSEVKASDIPSEGTEDYAPPYIHADDLSMLPPSFPSPAMPSAPPLDAENRHLQSGSGLTDEAIIPSYTITK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T238</accession>
    <name>A0A9P6T238_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007329</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000373">
        <property type="protein sequence ID" value="KAG0018309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T238"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318:SF95">
        <property type="entry name" value="F-BOX PROTEIN YLR352W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="205"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="275"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="211"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="227"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="275"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0018309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="815" mass="91564" checksum="099C268F013573EF" modified="2023-09-13" version="1">MEGLRELRELDITCIDKVNIKQDEVKWMVDSWPKLRRIKGLLELNASKFVAEGEGVVTVHSELEALPAIDGKYFFTKPSNPEDDHVSKENILFAANPNQQYRAPKLQFPWPYGSEIYQAVDTNLAKIQERQAYTTKPLDKLATFIFANVPDPEIRKDIFELLHITRSQLAITARQIQEMRLDNYACATGAEPAFMLEQEIATSEHAPELGTVTSTSTSILGSETGNSSSRSTEGISSSNQASGSEKGMLASHHLTKSGDGISISDHAPVIEAKPVAKKLKASKKSRGSSLAPTRRPKKSSNLLHIPEIKVEIGRYLENSELANCALVCRDWKKTFNQLLYSVVQISGESRTTPSLEALQRNKAFITSLSIMNDGVSTAYTKLVLPNLKTLKLHPRGASVGITWEPTAIILNHSNITSLELSRISTYDNTSFWESIASLRHLEELSVRYQMIYQENAEDSQEQDEEIHAFWDACSRVKKLNLHSFRFHHKDARIPLGGRNIPGPIIVRTLSNRSFPRLTDLTISQGAMHVTGQAMLIMKCPMLENLEWWVLSGQVKIPDMVRPIQDIILYLVSGKAPKLKCLMLESLPVEDLKFAEFISALDRRPLEELDVSETLFGRHAFDALRCHVSTLRVLNLHRCPNLTTPDILELLQTPFPHLEVLAVDRVRAQLIDPQSLWACGETLRSLSIEFELEQQLDPSGGSSMALMRTRHDINMAIFHCLGQLHKLKYLRVGYCEVSNQASIPLEIKLSEGLGELAGLKRLEWFAMGLMANSLGPEEIDWIVANWPNLNVIEGLPDVVRKIPRQTVLKRRGIRVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T282</accession>
    <name>A0A9P6T282_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Pyranose 2-oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">P2OX</name>
        <name evidence="9" type="ORF">BGZ80_005116</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000254">
        <property type="protein sequence ID" value="KAG0019898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T282"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051473">
        <property type="entry name" value="P2Ox-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42784">
        <property type="entry name" value="PYRANOSE 2-OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42784:SF1">
        <property type="entry name" value="PYRANOSE 2-OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="7">
        <location>
            <begin position="296"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase C-terminal" evidence="8">
        <location>
            <begin position="484"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF05199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0019898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="624" mass="69709" checksum="021E2B01D26BBAB2" modified="2023-09-13" version="1">METIHLRRAQDHPMRTSADYSLMHRPQDGSTAEGSSAFYPPALKPPRVQEKLKMGHKECDVLIVGSGPIGCGFARTLLDPAISRLVPEQGPEELKKLKVVIVDIGQHLSNVPGENVKNAYYYQRNVNNFTPIVQGTMQPISIAPNSTPLPYPTDPTVFEVKGANYVINNINPDQDESVNMPAAATTYAIGGMGTHWTCCVPRMAEGVERPPDDMGIPCQEWDELYEKAESMFLKSDTIFDSSLRQKVLLETLENHRSGCVKMPIAGQLNKHDKEQIVWSGADTVLGKLVDMESARRINEKFDLEILDQHRCTRLVVNYSDDGKNGDVVSATVRNLREKKDINIRAKYYVVACNPILTPQLLYNSGIRPEALGRYLMDQPMTFCQILLSKKIVRKIEKEAVDAELIPSDPERRKDPVPIPISDLPPALILKVNESRHWHAQIHKDTFSYGMVPQSIDPRLVIDLRWFGPMEAERHNRVYFDGRSDSKDLMGMPQPTFDITLSDKDKEHLSRMMKDMTDVAHILGGFLPGAEPRFMPMGTSLHFQGTTRYGPQNDGTSVVDPNSKVWGISNLFLGGNGLIPTPMACNPTLTSLGLAVKAARQILRQHYGKVRTPTPEEEGLGVIEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2E9</accession>
    <name>A0A9P6T2E9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_004896</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000245">
        <property type="protein sequence ID" value="KAG0020024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2E9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000793">
        <property type="term" value="C:condensed chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000796">
        <property type="term" value="C:condensin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007076">
        <property type="term" value="P:mitotic chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43941">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43941:SF1">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="290"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="381"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="462"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="41"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="294"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="305"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="389"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="464"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="491"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0020024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="829" mass="94199" checksum="15129A602F856F39" modified="2023-09-13" version="1">MDATQSEAASSSTLGDQLTTSENVKNLKRKVISVSKLMEVFKNKEIETAALKKQVEEAQKEIAELREKANDKTQLEQAQLEAKRAKAGQKAAEENLSRVTQRLRSVEALNTQLEAKTSGLDHVNNEVAELQKKLINMQKEHDQANRKSRQEMSEMRERLMRAEADKANRLEWLAEQKKKWEIDEKLRQSKQQQELQDKVDELEHQLEDIGTERYLETEMAKEELKSAEDKLRTAHQKLEENSLKLRSLNQTVLELRKENGTLERKLATFESERDTRDCDSISMEEFEEIIPSQDRPSTSKTTCTDQRRMSTSEATRVDHDLPRNQLDRALGTIEDLMTQFSVLRMFSGSQDDKQRMASLVEQVKTLTKEKQALQNELTRRLVEPPPTPHTSLTMSLPSTNPNTLATNASISAPISSDTIARAEPPNNVGRKRRVIESTPEVTPEIIPEPAKEPDMEALDHGISIDNSTTNASVNKRKRKSTVPAAPSSPLKPRKPRVSKKATKRPQPYTKLDAIAKVLPEKLGDLFDAVQAKTKEITDTVSAFRAKHDILQDDTETWTLEDFEPIVISNSLCTAEVYIVQLLCLLQERFPEISSPKASLVLCEGIASIWPSVFVMPSDVEPDDLQRPILKAFQAVLSTHQEAIKNVEIPFGYDTFIQKCKWPSLADAPFVDELVEEMMNVVRAPEFMDVCSKKHGYNFALRKALELLIVHGFEWIEIYNQFIKPELFKMMIDESLYAFALPLVAAITRETRYKPSEASEPADDTSPIRELLEAILDSEATLSHQTQSVLAILELSNGREDQISMAKKWHSNLNESDRRQLPEVLHEIFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2S1</accession>
    <name>A0A9P6T2S1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein transport protein S9 plasma membrane t-SNARE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">SEC9</name>
        <name evidence="4" type="ORF">BGZ80_004249</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SNAP-25 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000219">
        <property type="protein sequence ID" value="KAG0020398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2S1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048500">
        <property type="term" value="C:signal recognition particle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008312">
        <property type="term" value="F:7S RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019905">
        <property type="term" value="F:syntaxin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006906">
        <property type="term" value="P:vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15857">
        <property type="entry name" value="SNARE_SEC9C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15886">
        <property type="entry name" value="SNARE_SEC9N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.30">
        <property type="entry name" value="Signal recognition particle, SRP54 subunit, M-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036891">
        <property type="entry name" value="Signal_recog_part_SRP54_M_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004125">
        <property type="entry name" value="Signal_recog_particle_SRP54_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19305">
        <property type="entry name" value="SYNAPTOSOMAL ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19305:SF9">
        <property type="entry name" value="SYNAPTOSOMAL-ASSOCIATED PROTEIN 29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02978">
        <property type="entry name" value="SRP_SPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47446">
        <property type="entry name" value="Signal peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="3">
        <location>
            <begin position="337"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="3">
        <location>
            <begin position="491"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="274"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="444"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="284"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="295"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="306"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0020398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="557" mass="60049" checksum="5388EE10189ABDBE" modified="2023-09-13" version="1">MDSMNAKELDGEGKEFVDDPKRLVRVARGSGTTVAEVETLLQQYKTFAAMVKKMGGQNGLLKSMQGMQQGGAGNPMMNPNRMQQAMKQLQSGGIPNIPGMGGMDIQGMINQMGGMSGVQNMMKNMMGGGGFPGMPGMGAPGGAGGMPDISQMAKMMKSMASPLNSLHQIEKVFAMSLALSLFSYIQPSSFQYTYHSHFHLTLTTSMYNNNNNNSSGYGGNANYGGNNNYGANRPNNSGYGGNSYGGNSYGGNSYGGNSAGSGYGGNNSGYGGNGGGYNSAPRPGQYGQHTQQYGGNYGNNYGNGYGNNYDNNYGQQQGPIPGQETEEDVDRVAQQIRDVRQESLQSTRNAIRALQEADESAGRTLQQLGEQSEQLGRIERSLDSAQIHADNAQEKAGELKTVNRSMFAIHIKNPFNSTKRKERELEEAKRKAAEEMAQREAIRHEEYASKQRVNAAMGQGPYGRGPTDSNGYRGGPGEQSMYSFENTAEDDEAERELDQNLDALGGLLGRLNQSALAMNTEVNRQNERMTGITQKTDNVHGSVSHNTQLLQKIAKRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T335</accession>
    <name>A0A9P6T335_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_002537</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000163">
        <property type="protein sequence ID" value="KAG0021372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T335"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="301"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="312"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="343"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0021372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="692" mass="76865" checksum="83D9390C0327F2D2" modified="2023-09-13" version="1">MADDASSNVDDAVIVVFQLEGLANEAHHCAVFTVKNVEFVLSCYRIKKKIHVEAVTSANATNATFGVFRQLSILDRDNIIRSVNKIEESALSVRAVVKAKQALSQDRYMFSILLQARTNEKCYDLKSRYTVPRNILTPVMLKPRLEHPTLFLGTAQASYPTPTVSHLVNDIFIAAIQLEGPEAKSHHRAEITVQNMRFAFCCYKKKVTVQVEITTGANTTNSAFGMFRRYYILDCNNKVLSIRKFGESDNSLKAFVNLVDVLSMGRYMFRILLQAKANKRYYSVESYYTVPSSAPIPLILKPDGEPEYPESLPLPTPIPTPLSDPHTTAAPTSTGLELSRPHQPSSKSDQQPIPISISSDSGCEAKVDTAPTSTNLDLPRSPPLSSEDDQESISMSISSDPGCDAKAGTIPTGTNLELPQSPPLSIENDQESILMSISSDLSYEPKADSPLDMVEDDPFDVHFFHCDQTRRVNIIGAHKKKILEVSPKLHLFVTKTEAARDVLAADMSFTSHNDSHFPSQAPVTVDISYLSLPAFRAVMIYIYTRSVEAIFSNSSAVTVTSSSVNAEYDSSQNGRTEVHDDLTVLCMDQVLYLAQRFDVTDLVEAFTRLTLFSTKIDDVIEILVRNADNAEFESIAMDLIKSHFHEIFGGYVSNEVFEKFRDRLLCHGLKSKIMEMMGTIEETKVPSLVPPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T382</accession>
    <name>A0A9P6T382_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_002650</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000166">
        <property type="protein sequence ID" value="KAG0021327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="344"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="468"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="564"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="782"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="837"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="945"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1060"/>
            <end position="1093"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1117"/>
            <end position="1233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1299"/>
            <end position="1318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1419"/>
            <end position="1501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="114"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="374"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="468"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="491"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="567"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="782"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="802"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="841"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="960"/>
            <end position="979"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="989"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1064"/>
            <end position="1087"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1118"/>
            <end position="1129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1159"/>
            <end position="1173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1202"/>
            <end position="1213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1301"/>
            <end position="1318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1427"/>
            <end position="1447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0021327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1535" mass="166039" checksum="28395AF8AFF7319B" modified="2023-09-13" version="1">MSSENPTGRKSIEEMNGYLSDPPHIPGSDTSSQFSKESSRKKKGWTKSLKKATNSILYMAMPPTSADQMPMVVAQTPMSPDRLIPALHSPLLQTPLMSALESTSSLASTVITTTPFTPGTAASSTSSIGSSSMASSSSSKHTALRGSKTEYYGPINSEHSDTALRKQGSLPSSSEPRKRSVKGKERAGSISNSSQPFEHAPDSGPADAMGAMSLTSPASSPPSRPPPKHSIGANSTNAVSLSSMIENASQPDGQQVLPSPPPSPSNVARKRSEASVKKEKRRIQSTANSDNAAELAPSDMHSRDSSKQTEVKPTVNDPTLADANVLPMLPLNLSRLSFALGADLEHKEEQPQGSGKKSLATHAEETPQEIAAEVNKEQVNEDESKKTKEKTRPIHKATTITSIPGSFPGLSFSGPEPIPEVALPESFPTRPRYKAPRPPRESIPYVPLPGSFPVKPVLVEPEPMPEPVAIAPPPESPVIAPPPESHAIAPLPEPSPVVPQPPVEEPKPIPITTPIAPQSEPNHVETPVEERPQIPEPVAVSPSISRVPSVSNTPIVIPRESRAEIASQRSPFGSRNQSSEISTEMTGVVAIPRRPLPLSISENPSNRKTVKDVPWLWHQDGIHHQRLESHQILTKEQVFEQFHLDLEQEGPNGFFLFKLVKRFKKQDSSLLAISSSLLDAELSASPSSSPPNATPSSILESLEAVSVSQRLKRQLLLQKRKKQRKSSISNDDDESNLEALLAMSNNNISLQNLNSSLQEVIEAVEHMKVSEEWTSLLSQPGQLAQFQPQSQKPSYPDSDGEYTSRDKDAADIATLEKRRGVYATGRLDGMNLISKKKCMTAQRRPSAAQRRPSAAGNGRKGSVSSSASSGVNGADVGTQDIHGNERRGSEGGDVLQFKKTAVAQLHIYSRNGLKFKFDVMEDNELHFVEASKKYTFMDPLAAHRQPDLDANGTDGLSPLRSPSLSQASSHRLSNGTVATASDVGRAPRRSNSSMSKSTLSSTGSASSRRVYVTRLGRHTLLTYPEYKALAKSASSFTLGAKLLIQRSIAVATPNFYGNGHVKDSSQASVNDNAASASPTRSNLTPTPSGKEENVDYFSAKKKPRGLASKAVAAIKSPLTPSGANQQKSSPRPIVTPYNPNDYKNKPLTVLNSANGNSSGGEESTSPPTTSYTSLAEVDTNNSDSSPFPLPPSHINIPPEALSPLSSTPTAPSVSSPPPTPSSSSSNPYGSIKRQGNQAGIKFQHLFVTVHQRLQKLELDNGSSFYGSALVQWTVIEDPAELRWWRDKIGIQMIGRLDGDESVNSPAAKTSPLSGSNRSTLSSVRASYMSSDSMISDATSSLSSRGYKTHVSVERLGYRFLRVSGHMGTLKVTVSEKVEARAVALAVRAEMIKQKRMAHMNQGYPGHIEDLLEQPWVETEDTSVVSDGDSDLDGYDCGDDSNESENETAESNGLPIKKSKDGSNPYDGFEYDEWTGQTKPKTRPSVDRFSRRKRHNRGDKVQEPLIERTTMIVCQSKVFKGDWYMKNVYKFYPEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3H3</accession>
    <name>A0A9P6T3H3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_001041</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000123">
        <property type="protein sequence ID" value="KAG0022112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3H3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040180897" description="Secreted protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0022112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="190" mass="19290" checksum="A51B9525DA332098" modified="2023-09-13" version="1">MRFSVIAIVAAIAAVAHAQTDYYPFKPNGACVKSCLLTVGQKIDPQFTDDPTNPYFIASLAYAHERGTPKYIAYMTETGPCIGKCPADEQALYNLDYPAKNDWYVAHKNDAAATASATAPASSTTSAAAGSSTTFGSSQPTSASSSAANAASSSSTTATPTNTNKDNGAGSLAASSLVGAAVLLSAAALF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3I5</accession>
    <name>A0A9P6T3I5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Autophagy-related protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ATG22_1</name>
        <name evidence="9" type="ORF">BGZ80_000656</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation. The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Vacuole membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the ATG22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000114">
        <property type="protein sequence ID" value="KAG0022259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3I5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024671">
        <property type="entry name" value="Atg22-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050495">
        <property type="entry name" value="ATG22/LtaA_families"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23519">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23519:SF1">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11700">
        <property type="entry name" value="ATG22"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="7" id="KW-0072">Autophagy</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <keyword evidence="7" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="66"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="130"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="161"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="186"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="361"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="401"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="435"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="465"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="499"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="566"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="245"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="279"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0022259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="631" mass="69624" checksum="74BF0C88F6672D79" modified="2023-09-13" version="1">MADEMNVLSQTQSRKPFIESERAPPPMSTLSSDPISPSIPYRAENGLPLAEAKIVPLKKTEVRAWYFQNATYCVYGWVSAVMMVPLLIQDIAAKGGVEASNHAIPCDTSIPGYKCVKRIFGDHYLDPGTISLYISSLSAIVSFVVSLSIAAVADHGSYRKILLVVFAIIGCIASVAFFLVQSPSTFWLTAVLSPLAWACYNVSSVFSNAFLPIYVRAHPKVLEAVERATTCRIMHEIDEKNKIHSIDDNDYGSGSVDRRVGSHSNSSSSTQPGEALTAPTDTNTSVFSTSDQRKVEEQVSNDLSAWCTVASNVGSVVVQGEFGGSYGLLQSCRGWMRGQDHHCQKGGIGSYTHGLKVSSKVYLFFPVLGVLGFGNPIVLRANPSDFKTLRSMRQLSQVTKFIFAWFILSDGVNTVTSLLYVITYQDLNFSHTKSLVMTILVSIMAFVGAYLFLFIRQYWKLSTKFMIMLTLGLYALLTAYFVIPSYFTTRFGLRHEWEVWASVVYLGLIISTFYGVARVMVAELCPEGDENEWFSLFQLADKGSSWIGPFVTGAIQSITGEFRTGFWFPLALFAVGAVLLITVDMNKGKDEAIAYVKSEETKRQLTLPIPSVTITTTAENTTHHEAHKSQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T408</accession>
    <name>A0A9P6T408_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_010054</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000066">
        <property type="protein sequence ID" value="KAG0023232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T408"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000219">
        <property type="entry name" value="DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051492">
        <property type="entry name" value="Dynamin-Rho_GEF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22834">
        <property type="entry name" value="NUCLEAR FUSION PROTEIN FUS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22834:SF20">
        <property type="entry name" value="SH3 DOMAIN-CONTAINING PROTEIN"/>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
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            <begin position="36"/>
            <end position="215"/>
        </location>
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        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
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            <end position="290"/>
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            <begin position="444"/>
            <end position="596"/>
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            <end position="470"/>
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            <begin position="475"/>
            <end position="486"/>
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            <end position="508"/>
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            <end position="548"/>
        </location>
    </feature>
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            <begin position="568"/>
            <end position="577"/>
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    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
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            <begin position="578"/>
            <end position="592"/>
        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
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        <source>
            <dbReference type="PROSITE" id="PS50010"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="KAG0023232.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
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    <name>A0A9P6T4E9_9FUNG</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name type="scientific">Entomortierella chlamydospora</name>
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        <lineage>
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            <taxon>Fungi incertae sedis</taxon>
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            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
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            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
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        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
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        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000039">
        <property type="protein sequence ID" value="KAG0023873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <source>
            <dbReference type="EMBL" id="KAG0023873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="172" mass="18744" checksum="45CF005C78543C2B" modified="2023-09-13" version="1">MCYEPNNTGQASHTSGVPQEVWLFVAEQLGGKGALKCMTAHPSLKVGFNPEDWKRINLLDFNVLSRGCDKDDRCFGVIDNLIPGYDRDISDKTKYIQDLTIASPESLAKLGPGCINLLRFVCLQIPATYNPFAIVDALGTRPELKELGVSGEVPGMPDNGSPNVSYCPDVQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
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        <submittedName>
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    </protein>
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        <name type="scientific">Entomortierella chlamydospora</name>
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            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
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                <person name="Liber J."/>
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                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
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                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
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    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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        <property type="project" value="TreeGrafter"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16099:SF5">
        <property type="entry name" value="NUCLEOTIDE TRIPHOSPHATE DIPHOSPHATASE NUDT15"/>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T5S7</accession>
    <name>A0A9P6T5S7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">BGZ80_008895</name>
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    <organism evidence="2 3">
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            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
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                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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        <property type="protein sequence ID" value="KAG0024737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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        </location>
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        </location>
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            <end position="1261"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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        </location>
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        </location>
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        </location>
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        </location>
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        </location>
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        </location>
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        <location>
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    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
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            <end position="906"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="954"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1146"/>
            <end position="1155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1246"/>
            <end position="1261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0024737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1261" mass="138339" checksum="AE4E77DA54C5F1D5" modified="2023-09-13" version="1">MSSNGQSDTPMTQPTTKKISSIKSESENDMPSSERNGHNDSAGQSSTQIGDLDDHMDYTDETPVHPFAQAPQSSTALADSDSLIASQAHTPYMSSMQPQQHQQLLKLKTEHGFSSAPSPVNTPDIIMTNDETEGPSSVEPNRRQSSEASMGSTEPAEGDDQQQGRLAADTAMQGGRALTPNITATPTSSQIDAPSTAASSAPSSRRPSLRTMPATLPRSALQEETIALFKQYRNLIPCAKCFCRNTIQRDGMSDGNLRFKCRPPVSMSLICNKSYSESKIRNMIAGVVYGNSLPDSNTSASTGSGDNVLALAPPPMKSSRRGSKVDNSKSPRIGSEISPERLQQRLQQEDIQGRDQIHDERDPEEAHSTHPMDPMDARRPSQSHLPPHMQQQGSSSRRGSVQQHYQQDVRRPSLVGDESMMMDYDDQGPQMPPSHSSHLQVPGTPPMEGEDPRFYRSRNSYSHQSRAVTPTGPAQQPPPQQAGGRQLHKLHHSHSHPNIGQLRQQQYLEQQEHQREHRGSVSGMGYPSQQRATPRQIVRRDSSQYMSGPERRSSHPSPVLNASGSKYTAEAHSPVLSSSPRSSPGRESAHHNQAKGPSTHDSVLSMPTLRLSSRYDESYFQRRMSQPHPGHAYGMPPPLPSPLSHSYDRRPSEVEEYPQMHREKYERLNANTMLTPSSALGSSRQQQQKGRPHYPSGSPSGGLHPLDGDGVDEASSRQPLTPPMKSSYPPSLASASAVSSPWIGSNGGHGSTSQNATTPQFSHSVPMGNQARPSLRHHYSSSSLYYQSPRPDDRDRFERDHERDMSPEYQEVDADGRPNARMRPQGVKRKSLGQPLSRSNSNQNLYSTNAQHYHHHHQNQHLRGNADHYSQRDLNEAMPRSSIKLTCYPKNNGNNNDAPLSPTSRTLDTSDALALQLEQTSKLVIEIRQPRSLQSYTSAASLNDREKSIHRSSSHPNLSLARSSSSILGHRRSPSIDQSECEGSSSKKRRSDSDSVPSGGNSNGGDQGSASSDSSPVAEVAPSNGGSAVQVFGIDYISKSDRAKDTVGLGLSTSPLTSSPTMEALQVAKGSSYVVLEDQKEMGIDYSLFTRVETAGWRILIPPNVVASFRSEDFGLMLKPKGMEELDDGEESEEQSLEVGKKSVSEFENQSLEQRQLQRDVEKDEDEEDVNVEGVRRIALRDDDKNEPRTALAAEGVKSMVLRQSIQDDDQEMQEMSASTSAATVECKSAVVKTVGPAQNAGQEQGDVEMDKEQDELLDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MCY5</accession>
    <name>A0A9P6MCY5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">WD40 repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_008440</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004572">
        <property type="protein sequence ID" value="KAF9992720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MCY5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848:SF8">
        <property type="entry name" value="F-BOX AND WD REPEAT DOMAIN CONTAINING 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="41"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="84"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="126"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="168"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9992720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="260" mass="28068" checksum="4395AD569F12A8AE" modified="2023-09-13" version="1" fragment="single">GHSGDVFNIAYSPNGDQIASGGEDETVRLWNVETRGIIHILGGDVGEVYSVSYSPKGDQIASGGRGDCSIRLWDVKTGNLTCVLQGHDNCIFSIAYSPNGNQIASGSGDETVRLWDIETGNCIHTLQSHHDSVSSVAYSPSGGQIASGSWDKTVRLWDIETGQCLAIISGFNGYVNDVAWRNTLNGQYLVTGSNDKSVRHWEIIKEQDEYKVQLHWSSSHDSLTVTEASFNCVQGLSQTNQRLLSQRGAGALSPTSSLDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MDT5</accession>
    <name>A0A9P6MDT5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007877</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004116">
        <property type="protein sequence ID" value="KAF9994251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MDT5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="36"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="137"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9994251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="163" mass="17827" checksum="D505DFB5553429BC" modified="2023-09-13" version="1" fragment="single">MQYEKSRRSMEERIRTHPSLEEEGYDQYRREHQHHVNSPQSQNNSQSYQVARRSSQTPYVTDHRGRLPSLLNPDGQDQDYKDPEIKKMAFADQTVPAPVPAPVPAPAPGAPAVSTALAPVPRRGSGGTTRIAPFPAPGIIQAPSSSSSTTGSSIPSSRTGRRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ME29</accession>
    <name>A0A9P6ME29_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_007747</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004011">
        <property type="protein sequence ID" value="KAF9994690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ME29"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF309">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14510)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="9"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9994690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="99" mass="10568" checksum="4FE43C80D77EB96C" modified="2023-09-13" version="1" fragment="single">MSSETTKPKVLIVGAGIGGLTLGAILEKANIPYEIFERASALKPLGSALAVGPPVMPMFIQLGIFDQIIEKGIPYRESNMYSEKNELLLHSNNVAGAPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MEU7</accession>
    <name>A0A9P6MEU7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Eukaryotic translation initiation factor 4E</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">TIF45_2</name>
        <name evidence="7" type="ORF">BGZ80_007415</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the eukaryotic initiation factor 4E family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003795">
        <property type="protein sequence ID" value="KAF9995788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MEU7"/>
    <dbReference type="OrthoDB" id="590761at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016281">
        <property type="term" value="C:eukaryotic translation initiation factor 4F complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000340">
        <property type="term" value="F:RNA 7-methylguanosine cap binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.760.10">
        <property type="entry name" value="RNA Cap, Translation Initiation Factor Eif4e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023398">
        <property type="entry name" value="TIF_eIF4e-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001040">
        <property type="entry name" value="TIF_eIF_4E"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11960">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11960:SF8">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4E1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01652">
        <property type="entry name" value="IF4E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55418">
        <property type="entry name" value="eIF4e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6 7" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5 6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0810">Translation regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9995788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="204" mass="23317" checksum="51FA82A8FBEC1294" modified="2023-09-13" version="1">MAQNDSLAVPSGDKYVTVFNDPVNFNVKHPLHNSWTLWFDNPGKKSNANTWEQSLKELITFDTVEDFWGVYNNIMKTCDLSISSNYHLFKQGIKPMWEDTANKHGGKWSIQLPRNKTMNDIDGIWLNTMLACIGEAFEHENEVCGVVVSVRRAFFRIALWTRSSDNQNVAMSIGTTLKRETGIDGMFEFQPHHETKSSGKPWTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MHD7</accession>
    <name>A0A9P6MHD7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_006376</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003146">
        <property type="protein sequence ID" value="KAG0000366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MHD7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0000366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="101" mass="11313" checksum="010B8D9469B27D15" modified="2023-09-13" version="1">MPKTETAQIRTQLNNSEVLIRNLVIFSRTKAVRTLSSDFGQVSISLTAGLTDKSLPSETSRHQTSRRLYVTKNLNLIVAKALTINGFTVFPHLHKFTTIDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MHF7</accession>
    <name>A0A9P6MHF7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_006244</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003076">
        <property type="protein sequence ID" value="KAG0001058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MHF7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0001058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="386" mass="43253" checksum="5E53B16A6F0A6D75" modified="2023-09-13" version="1">MLDYIQAIAETRGHLNRAGIPDRIWTIHHITENHQKRAMASILNSAAGTDSARIVNGGLNGIVLKRGRIIWVCNECYDLLLARRPISVEDLVSTAEFVSLTSQEPSTDVVLRSSASVIIFQNTLSNSPDLESIKVEIKPEFFEKKDLNSTSNLFKELGAAIRGCRKLKSLEIICHSLDDRPYQGLKSVFECSKLERLILRGMKNLLQGPQISMKCKSLKELILDSVLVNTEEAATNLRELVGRNHDLTSLRVTRAKITSESAVVLSSYTPRDSRKQIERLVTLDLSDNNLESIEAVSLVELALGENKFAGLGESHKLRHLDLSKNPRIDDTCCRAILEKFEKKSHPLETLNVESTSVCPQTTSDINNYLHKCKKNKATHGLHWIHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MHG8</accession>
    <name>A0A9P6MHG8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Heat shock 70 kDa protein 12A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">HSPA12A_6</name>
        <name evidence="1" type="ORF">BGZ80_006311</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003107">
        <property type="protein sequence ID" value="KAG0000741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MHG8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10229">
        <property type="entry name" value="ASKHA_NBD_HSP70_HSPA12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187">
        <property type="entry name" value="ALPHA KINASE/ELONGATION FACTOR 2 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187:SF5">
        <property type="entry name" value="HEAT SHOCK 70 KDA PROTEIN 12A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0346">Stress response</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0000741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="502" mass="56470" checksum="8C1C857B52063888" modified="2023-09-13" version="1" fragment="single">MTLTDFDPEDYPIVVAIDFGTTFSPKQNIQYAKTPTLNLYQEVNGKYRMIEWGWKSKLQMETPAASKYIQLYKYKPHLDENLALVPWNDKVSVPDAISDYLRALHEYVVEKILQEFGRSYSRKSFRYCLTVPAMWSDKAKDVMRKAAVRAGLISGDDHPDRLTLVSEPEAAALYCEKACKQYDLGHGDRFMICDAGGGTVDLIVYEISMTAQGRHLSEVTKGHGASCGSMFIDLNFGNLLIKKFKRQGAEFPKSVIQTLVETFAYQLKPQFDGEEDMYLALPRNDCFDDIKDPRSIGIDGGYMCLKATELKKVVFEPVVMNVLALIQEQLDGAKNCSAIFMVGGFGSSSYLLQRVKQRFSNMVKTISAPHKPEMAVVCGAVYAGLNPKIVTARVTRRCYGVGVNERFEEGVDPISFKIMKPDGARCKNRFSTFVRKGQKVQVDECVTNSYHFTKSDSTSNFSINIYAIDGYPPRYTTDYGVSKLAEISIPDPFNPWDSIGHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MHV7</accession>
    <name>A0A9P6MHV7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_006138</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003016">
        <property type="protein sequence ID" value="KAG0001670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MHV7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0001670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="455" mass="51910" checksum="CA640F74D6431578" modified="2023-09-13" version="1" fragment="single">MNQSRLAKWDSNCLDTYILLPLDYGFVNNRDCFFISHFWRTRSHPDPEGIDMSLFRDDLRDQQWSYVWIDWTCLPQAPRSKEEDRYFRKMLRSIPLLVQDCGFGWRFPTFEARAWVLFEVATFLLNHKPPFPITDDLETFFIHVNEMVRDGVQPTLKKHGYQCTNQSDLSLVTGWMEILVILFKTVPNVRDRQEIIDAIYAPVAGSLKHFGLNLEIDKSAGTITIDGTIHKFTPIYQLTRETSEQQPPNSALQPPLPGSLVKIAEIDKAIAATDSLASGIDSDIQADFDYLSGPWGCEELLVLDKAALSELLYKVLQDDQTAGLRSRSMDTHKGDKQHPPYVQLNSIGKTFRPYRITKRQDGRLVLYGHEALYRAKRALDRAKNPSVTPSTADLITELIDIGSELQGRVRSIGSMLNDAGGMMLMQQVHKAIRDRLGVSRARELEYAWDGVGDWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MIN3</accession>
    <name>A0A9P6MIN3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Homeodomain transcription factor ste12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">STE12</name>
        <name evidence="12" type="ORF">BGZ80_005915</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the STE12 transcription factor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002912">
        <property type="protein sequence ID" value="KAG0002791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MIN3"/>
    <dbReference type="OrthoDB" id="1095242at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990526">
        <property type="term" value="C:Ste12p-Dig1p-Dig2p complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990527">
        <property type="term" value="C:Tec1p-Ste12p-Dig1p complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:002343">
        <property type="entry name" value="Zinc finger protein 33A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003120">
        <property type="entry name" value="Ste12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052127">
        <property type="entry name" value="STE12_transcription_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47427">
        <property type="entry name" value="PROTEIN STE12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47427:SF1">
        <property type="entry name" value="PROTEIN STE12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02200">
        <property type="entry name" value="STE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00424">
        <property type="entry name" value="STE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="12" id="KW-0371">Homeobox</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="377"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="407"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="228"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="316"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="423"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="237"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="327"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="357"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="447"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="484"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0002791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="753" mass="83326" checksum="F594AACE57D9B7D8" modified="2023-09-13" version="1">MELSKFLLPTGETISCVLWNELYHITGTDIVRSLVSRFESFGRPVRNIKKFEEGVFSDLRNLKPGADACLEEPKSPFLEMLYRNNCIRTQKKQKVFYWYSVPHDRLFLDAMERDLKREQAGTEPTSQAVAEPALSCTLETVRDLVERLSRRTIEMNTITETLQSFTPDGVAPMTRQLPTVISPLATSPTQAQLVPEGGMTTTNVTTAVNTRSDSNGSSFENRLGHSFIEDVGSDDNSESKVPTDREGVHLTGSEPLNHASDANAGLFGSFTLFEGSPTYKKRRRRSTANPSHLSEQIERHADIISNGGDAVLHSGSRNGSFDFDQDSSDRYLDGAHKGNGYPGGFHDSSRPLHHHGSSSISSMQSIHGGSSNSSRSYACPVQPCGRLFKRLEHLKRHWRTHTLERPYACNICSKRFSRSDNLAAHRKTHDKPSWANDDDSSAPRGDGEDDEIEGDDQDNDDPRISKGYTSDQSMTRKRPRMHRDRGMESMSERESISGLSSGDEDDDLNMASMMKLSSLTQEQQQLLQQHRQGFAKATTPMLQAQHPPFALSSQRPNVFPELASQNFMPTMSMIANQQYAPFSVGPLSAGFGGFLANQPMQQPPLFTLEEEEDENEEITDMEKLRYKYEYEIKAAIDSTPVLSEVTKMMATPYGAGAFGYGGAIPDYVAYNQYPLATPVGLGGRFPFDPTATAVASNTFATPMVPSSATSNGSFSTTPAAPSNYPVVHTAALPPSHHHQEYLEFTLGSMLPTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MIT7</accession>
    <name>A0A9P6MIT7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_005831</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002870">
        <property type="protein sequence ID" value="KAG0003246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MIT7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015606">
        <property type="term" value="F:spermidine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="entry name" value="Sodium/glucose cotransporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050277">
        <property type="entry name" value="Sodium:Solute_Symporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48086:SF10">
        <property type="entry name" value="AGR155CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48086">
        <property type="entry name" value="SODIUM/PROLINE SYMPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="110"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="177"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="215"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="256"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="301"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="344"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="369"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="398"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="439"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="490"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="497"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0003246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="510" mass="55708" checksum="1DF8B703C7538E68" modified="2023-09-13" version="1">MSLVSITYGLAVSTIVFFGLTALYLAHRRHKIKEDDTEFFLTARHSVPLRTIAWVIFSMPAFVVSAGIIGLIAYSISCGLPILIVARVGAVLHRKYPGVLSLGDFVQWRFGTIPTIIVTLVMLLTMSLALCAEYTSIGNLMELVIGGPRLPIIVCVAFVTSIYTAAGGLYVSILTDVGQGVFGILLLIIMYIYVAATYRPDHLPIPLPEELGPNYWGWAAMVAMPISMTCATFFSEAPWQRIWASADEKALRKGSLWGAIALMAVCFLYGFGGFLALWAGFPRTSTDGSTAFFDLLNAGNATAPPWIVVLAALATVTMNEGCVDSLQNGIVDTLASRFFRGKSVWYPRVLVFVINVPIVFVSLKGYNIINLFLVGNLVCAICSVPLLLGLVERLEGYVTGWSMVFGMITGFFSIVVFGYFKTGNLADGMQYTFIDYYDWPSFVLPLVFSFIGVFIAAAIEGAIRKACGFAYPVPLTPPPRAHVEQKEEMSIGSLEYGTEKPIETEGKQSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MJG2</accession>
    <name>A0A9P6MJG2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005629</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002772">
        <property type="protein sequence ID" value="KAG0004373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MJG2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="135"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0004373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="226" mass="25503" checksum="A6199B11526E5D1E" modified="2023-09-13" version="1" fragment="single">PELDIFSREATDKTPPQVRRESSLLATGFGVTPPQLERKLPLLDTYGLPPKVGVAPPQARCRSTSFDSDKLPPQVRYDLLFQSLVSELPPRDDLLLHAKDDLSQQAKRELPPKVGQRLPHFKNLVSFLLNDDWPDSSSDSSNDGSSVGNSDSSDDEGDSEDRKPEDSKEFDPTNWTPQRKMQFTSEKAARECLQEWAWKKGFDVHLGRTKRNEGINQRGTIVNIYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MJP5</accession>
    <name>A0A9P6MJP5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_005490</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002700">
        <property type="protein sequence ID" value="KAG0005242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MJP5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="467"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="71"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="555"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="623"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="659"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="773"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="969"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="497"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="71"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="88"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="563"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="574"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="626"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="782"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="801"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="815"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="978"/>
            <end position="991"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0005242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="991" mass="110199" checksum="886AA53C54250B34" modified="2023-09-13" version="1">MDTATWTKIGNQNSVGLSGATAVFHEVTASIYFFGGMVNQTTRNVITYQFSLEQELWYALAPRVDPFTASFSTTSSQSSPSPSPTPSSDDDGDDDDDGDSDSDTDSQFLEPVWYDTVSGVWTPAGLMGDDAVVMYGGMKPYGVGLSIQDPNCYIRKVTVFDLSCRSWTTYDFYNQSSVMKPRVNHTMVLRPPGASGGNKTAWTAYIFGGFDGKDEQDLLVVTLDIPTTENSVVNNCRAKTASSPTDSPDYLLGTTADIPKNGTVQELLLQRPDLSSDVSTLETCPMRTSLNLLTTYTSTIRPGEEITFKTYIDAYELDIEFNVETNQSLPLDFRTQNVWEGFMNMYWRADHGLTDGSSQASSPTPSDVQSNETAIDGPIITYSGTLNTSELMDRWTKYSGLDSSPTWSALRASTSSSIVFSAGDPRRFSGYYIYSLKNSNPSTLTFNITVNLLNHSSGSKQGSGANLATLGIVMGGFILGVILLVLVAIKVRKRLRKRRALRAAERLRLMEEREEQEEEERRRLANLALASPENLKNMKPIYRVILGFDRQQQQQQGFENSTLRHRTLGRTKKSSATGATKTAVGLSGADTEVYSIPRLRLDPVESHPEYGKRSSRARSDFIRDLGSSSSTSGGSHLDESSETCTIRSDMRESIGAAGSLSTELEEPRGMLNDNSSNFSSLPCDSSLRSFDHLEMMKPSTELEIESKGQGDHLGTTNLTRERRSGIWNEGSVGDSDVIKLEVLKPYDVSGPETISNTRRRNPIGVQPISIEPLPFHGGLVPRTKRHYRRYQRSISRRYPRTSNRTSPQLSDRSVSRSSTGRGTQTTPLQGSLRRAKKAATRMALESRTGSASGLDMPMDNEDEPWESIEMDQYDTTASTVQEQQKPENTWTTPLARMREEKEYEPGPLLAVNVLIVFPGDSETIPVNPRGSSTEISEVKCLPPMAIGTVFAPDPVRWWAYKARQQQDRRRYEREMKRLYHHQGHQRSRKPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MKE9</accession>
    <name>A0A9P6MKE9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_005422</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002674">
        <property type="protein sequence ID" value="KAG0005590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MKE9"/>
    <dbReference type="OrthoDB" id="1882547at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006004">
        <property type="term" value="P:fucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11296">
        <property type="entry name" value="O-FucT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019378">
        <property type="entry name" value="GDP-Fuc_O-FucTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10250">
        <property type="entry name" value="O-FucT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2" id="KW-0294">Fucose metabolism</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="49"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0005590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="547" mass="61857" checksum="533852F6CF50C66D" modified="2023-09-13" version="1">MKNSHVSLARAILMICIASMMLALIHIHYTSFYSREQSVANNRTFENNDNQHEIYDNSTPPSDPDSEPGTIDLPTPQPKPDTQSKLDTQPKPDTQPKPDTQPKIDIPPASPKPEIITAETKLSFTTSYSNGTVTKVFKPAFYKDPQGARNEMGSFLDTLAERYSQETIASKGFFSYLPMGGGNNQFSSLEKAALLAKDLNRTLVIPPISPSSHIKLWSGPRYSEFYDLKEFSVKSGISIVEWHDIKHTPEKPTADLTRHWTEYSEDFPCIPNGAIGIKNKNLYDHFRPQFLMNFKAVEPPVKDRTMGRATKYAYAKDVLLQDKDARNPDVWKCLSCPYFLKGPSLMDRAWKEVGLHMRFTDKIEGMVDDILDTLLPKSKDVNRRHPEFIVIHLRRGDIVTKCKKGQSEQECLVQIEEIAERVDAIEKKRRIKALHATNGNNANVVLERLPVLVATNEKRQSELKKLEELGWILLDHGDKKFDSKGIEIPSKAIKLGTMSSLGEFYPPMIDAVLLTRGDYLIGMAKSRMSQLATQRGAAWYGHTTMLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MM54</accession>
    <name>A0A9P6MM54_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004993</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002491">
        <property type="protein sequence ID" value="KAG0007167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MM54"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0007167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="150" mass="16395" checksum="1193E6D541165921" modified="2023-09-13" version="1" fragment="single">QDYLKDQDYPKDLNCNPCDGNPHSMEYSDLLSDSELPCEDETVDYSTGPQDRSFYQDNTMGNVTNGVLPISVAISEIDASTVTVHENNKVVELTDDRAQVAATDLNKRKRSEYEQIVPESPERKRMALVAAALAGVVVGSIGTIVTLASI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMH1</accession>
    <name>A0A9P6MMH1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_004093</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002127">
        <property type="protein sequence ID" value="KAG0007903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMH1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0007903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="75" mass="8247" checksum="87B9CE57FA64CDDA" modified="2023-09-13" version="1">MDRTHGSRGGHSSAPRSADSIVQSFIRYSVPSHRIEQTMEAMYRTFEIDGSFAFLRGLTMIPFGDSDTHTPAGGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMS2</accession>
    <name>A0A9P6MMS2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein bL34m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_003971</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL34 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002085">
        <property type="protein sequence ID" value="KAG0008003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMS2"/>
    <dbReference type="OrthoDB" id="431691at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.3980:FF:000001">
        <property type="entry name" value="Mitochondrial ribosomal protein L34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.3980">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00391">
        <property type="entry name" value="Ribosomal_bL34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000271">
        <property type="entry name" value="Ribosomal_bL34"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01030">
        <property type="entry name" value="rpmH_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14503:SF4">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL34M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14503">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN 34 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00468">
        <property type="entry name" value="Ribosomal_L34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0008003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="108" mass="11978" checksum="CD4D4953C095A6FA" modified="2023-09-13" version="1">MFAAFTSLRTKLAPVARTQFTAIASAPSPAVGVSSTNLSSSIFASLTGFRVPSVFGSNQARFVTYGREYQPSQRVRKRRHGFLARMKSRGGRKVIQNRLLKGRKYLSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMY3</accession>
    <name>A0A9P6MMY3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004082</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002121">
        <property type="protein sequence ID" value="KAG0007918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMY3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0007918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="123" mass="14480" checksum="9C9012F60AAD54AE" modified="2023-09-13" version="1">MQTTAASNVGHAANFDRSMMANVREIRYETELERALREIDECEEEPEREGEDQLDEHYYLDAYKTMDQRLYRRPVLPVPPPPRPMSSEMYKKHHRMSLPIQNLMSKRISLGNTLRWKGRATAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNQ3</accession>
    <name>A0A9P6MNQ3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_003680</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001994">
        <property type="protein sequence ID" value="KAG0008225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNQ3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0008225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="282" mass="29742" checksum="C7651A141DBE6E8D" modified="2023-09-13" version="1" fragment="single">MNRAPNSIASTAFRGGVLYVQVSTPENILGNIYAVNDPNASRGGRGGTNGISNTLYYTLQTVHGLHNFTVPGNQNLVSMVSGTTIGNSIPNGIRHDIFLAFTPSGASTAPVLVRLQPSSTGPVSVSNTDWILYQDEGGIQSPVLAPVISSMAQIASGQKDLSSTPYSTSVEAEGSAIYEIYWNSLSTGDFQLQKVDMSTLGTPSDPTSSPAITVLWVQTFSLLDSISSPKLLRLSDGGYFDGVVIGKCAGSSQTCLVFFNDSNNPSMAVTNLQFYSDNCFAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNX8</accession>
    <name>A0A9P6MNX8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_002891</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NADH dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001738">
        <property type="protein sequence ID" value="KAG0008939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNX8"/>
    <dbReference type="OrthoDB" id="3244603at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003954">
        <property type="term" value="F:NADH dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045024">
        <property type="entry name" value="NDH-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054585">
        <property type="entry name" value="NDH2-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706">
        <property type="entry name" value="NADH DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706:SF50">
        <property type="entry name" value="NADH DEHYDROGENASE (UBIQUINONE)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22366">
        <property type="entry name" value="NDH2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="EF-hand" evidence="10">
        <location>
            <begin position="478"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="10">
        <location>
            <begin position="519"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="40"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="41"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0008939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="663" mass="73779" checksum="AB4DCB513AB53A4A" modified="2023-09-13" version="1">MLRLISPRGQTIHTLTRVTAPALQQSLNFSHRRLPAVARTFSPQSTHRFTSKSFSTTGPSLSSQAPPPPSPPKPKKRSLIYRAGRALLIIVAVPVAGSLAYATYDAVSYEVDELHKRPPRRVIGGPKNLVMTHGCKGSVLKAEEIHENDPRQRLVILGSGWGAVSVINQLDHKKFHVTVVSPTNYFLFTPLLPSATVGTLELRSLIEPVRRLLAKLGGYYLEARAEDVDFENQLVEVSGVNKSEGRKFYGMSDYFPYDKLVIAVGSESMTHGVEGMEYCNFLKSITDARDIRRKVMENFEKASLPTTTDEERRQLLSFVICGGGPTGVEFAAELYDFLNEDLVGYFPAIPPEEVQVHIIQSAGHILNTYDLKISEMTEAKFKRDNINVITGARVGKVNPTSVIYKDKATGKEVEIPFGVCLWSTGVGMTPLVKTLVAKLPTSQSNKHAIETDAYMRVLGTPKETVYAIGDCATIPQPQFVGKVMEYIKEHDTNNDGTLSYEEFKSLANKIVAKHSILKVFLAHIDEVFEKYDMDHNGKLDFDEIQAFLRDAEKSCTALPATAQVANQQGTFVGKRINTIYDLTSAEEIEKLPPFKYTHLGSLAYIGGNDAVLDMGRGMVYSGLGSEYMWRSVYFTEQVSMRTRLLLLLDWSKRAVFGRDISKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPV7</accession>
    <name>A0A9P6MPV7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">26S proteasome subunit rpt4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">RPT4_1</name>
        <name evidence="12" type="ORF">BGZ80_002641</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001659">
        <property type="protein sequence ID" value="KAG0009192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPV7"/>
    <dbReference type="OrthoDB" id="1664597at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008540">
        <property type="term" value="C:proteasome regulatory particle, base subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000008">
        <property type="entry name" value="26S protease regulatory subunit 10B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000027">
        <property type="entry name" value="26S protease regulatory subunit 10B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000034">
        <property type="entry name" value="26S protease regulatory subunit 10B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050221">
        <property type="entry name" value="26S_Proteasome_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032501">
        <property type="entry name" value="Prot_ATP_ID_OB_2nd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23073">
        <property type="entry name" value="26S PROTEASOME REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16450">
        <property type="entry name" value="Prot_ATP_ID_OB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7 12" id="KW-0647">Proteasome</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="11">
        <location>
            <begin position="172"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="25"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0009192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="395" mass="44278" checksum="57BCC03E496CF490" modified="2023-09-13" version="1">MASASQDSDPRANALANYRKKLLEHREMEAKVKDLRMGLRELDRAFNKSEDDIKALQSVGQIIGSVLKQLDEDRFIIKAASGPRYVVGCRNKLDKSKLKLGTRVALDMTTFTIMRMLPREVDPMVYSMGMEDPGSVTFAGIGGLSEQIRELREVIELPLMNPELFIRVGIKPPKGVLLYGPPGTGKTLLARAVASTLETNFLKVVSSAIVDKYIGESARVIREMFAYAKEHEPCIIFMDEIDAIGGRRFSEGSSADREIQRTLMELLNQMDGFDHLGQTKLIMATNRPDTLDPALLRPGRLDRKIEIPLPNEQGRMEILKIHALGITKQGEIDYEAVVKLSDGFNGADIRNICTEAGMFAIREERDYVIQEDFMKAVRKVADAKKLEGKLDYEKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPX8</accession>
    <name>A0A9P6MPX8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MULE transposase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_002713</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001680">
        <property type="protein sequence ID" value="KAG0009132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPX8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031052">
        <property type="entry name" value="FHY3/FAR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018289">
        <property type="entry name" value="MULE_transposase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31669:SF251">
        <property type="entry name" value="PROTEIN FAR1-RELATED SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31669">
        <property type="entry name" value="PROTEIN FAR1-RELATED SEQUENCE 10-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10551">
        <property type="entry name" value="MULE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MULE transposase" evidence="1">
        <location>
            <begin position="34"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0009132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="197" mass="22739" checksum="3318C2FC1B5B3EA2" modified="2023-09-13" version="1" fragment="single">LCGAVYIDSDSNELRRIFWMSPRQRRIYRRYHDVIVQDNTAKTNKLFHLAVFVAVDTNGKSRTVVTALALRETSLDYEWLLMQLLDGSKGDDGRKLAPKVILMDEDLGMDLALRHKLPDTHIVNCIWGLATINLPTNLIRRLGGAAFKTFMVKLWLAQKSLTSGEFEARCEVLREEALAKNKRTARYLRRVFKHKHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQU0</accession>
    <name>A0A9P6MQU0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_001633</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001377">
        <property type="protein sequence ID" value="KAG0010269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQU0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051694">
        <property type="entry name" value="Immunoregulatory_rcpt-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549:SF6">
        <property type="entry name" value="MID2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549">
        <property type="entry name" value="PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040360842" evidence="7">
        <location>
            <begin position="23"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="126"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="183"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0010269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="306" mass="31848" checksum="52620330924DAF16" modified="2023-09-13" version="1">MKFKSNVIIPLLALALAPVATAAIEIPPLFGTATSSTSAATSAATTSEIPTSTSPVITTSLPTANITIPTTPISNTTTTISTTDTVKKTTTVTDTATITTMNATTTTTAPAATTSPAETTKSNVPLAAAGIVVGSVVIAAAIGIWVFRKWKLSPSRDFQSKIRGDDYSDYPRTYEADTLHLRQMGDQSGDPTPIKSPYNAQTAFPTPQDEFYDPNYASSKDHGGYGQGNYGGQDYGMGGAAPGFDQGYGYNHEYGHADYAQPQAGGYGHGDYAPSQVGGYAPTQVGGYNQGGYPHQNAGGGYQHGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRA0</accession>
    <name>A0A9P6MRA0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thiolase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_001585</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001364">
        <property type="protein sequence ID" value="KAG0010326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRA0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0010326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="61" mass="6444" checksum="1A4E06EC4681D693" modified="2023-09-13" version="1" fragment="single">MASRLAQIVSHLAIQSTSAFSEAPSVLTRIGVKSSEDVVIVDAVRTPMTKSKKGGFKDTVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRE3</accession>
    <name>A0A9P6MRE3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_001311</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001298">
        <property type="protein sequence ID" value="KAG0010621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRE3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0010621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="153" mass="17865" checksum="C5B1D87946EC1E1C" modified="2023-09-13" version="1">MLERNRTQLVSRLSQPRVVKHIFMDHQYHKDFVELFQRIQEEAPKLQRNLDAMAWKDEFLGSTRSLEQLSYLVNKQRSPMQPKGCSQISIPYCNVPNKPKFIYLQMVHDWDLVLFRVIAAQSVRDGSITDLLAHHVRLGGSVNNTMVFLKLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSD6</accession>
    <name>A0A9P6MSD6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_000439</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001091">
        <property type="protein sequence ID" value="KAG0011765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSD6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047429">
        <property type="term" value="F:nucleoside triphosphate diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017111">
        <property type="term" value="F:ribonucleoside triphosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009141">
        <property type="term" value="P:nucleoside triphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16018">
        <property type="entry name" value="Enpp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002591">
        <property type="entry name" value="Phosphodiest/P_Trfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10151:SF120">
        <property type="entry name" value="BIS(5'-ADENOSYL)-TRIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10151">
        <property type="entry name" value="ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01663">
        <property type="entry name" value="Phosphodiest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0011765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="361" mass="40807" checksum="5A2B02CAE4C58A4B" modified="2023-09-13" version="1">MISVGNKGVVAEYMKPSFPTLTFPNHHSMSTGLYPSSHGIVANMFYDPHLDEDFNYKIPDKSWDPKWWGGEPIWETAVLQNQRSGVIMWPGGESLRPVRPTYHERFRPATSVSEKMSTLLGWLDKPREERPTVMTVYIGEVDTAGHDFGPDSRRCAKALGEVDSALGELLEGLRERNLEQVVNLLLVSDHGMSYVTPLKCIYYDDYIDTSDLLLEESLQPHLGIRTKDPKRQYEMFHTLKSVQQKHNLPFKVYTREEMPARYNYAANDRIAPVIVLADPGYVMTRRDMGLSVVGVHGWDNESKDMRAIFMASGPSFPSQGPTKLQPFENVELHEIIARTVGLKVKPGSTDGVLNGYVSRTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSI2</accession>
    <name>A0A9P6MSI2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">beta-N-acetylhexosaminidase</fullName>
            <ecNumber evidence="3">3.2.1.52</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BGZ80_001069</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.</text>
            <dbReference type="EC" id="3.2.1.52"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.52" evidence="3"/>
    <dbReference type="EMBL" id="JAAAID010001237">
        <property type="protein sequence ID" value="KAG0010940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSI2"/>
    <dbReference type="OrthoDB" id="428480at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004563">
        <property type="term" value="F:beta-N-acetylhexosaminidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030203">
        <property type="term" value="P:glycosaminoglycan metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06562">
        <property type="entry name" value="GH20_HexA_HexB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000063">
        <property type="entry name" value="Beta-hexosaminidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.379.10">
        <property type="entry name" value="Chitobiase/beta-hexosaminidase domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025705">
        <property type="entry name" value="Beta_hexosaminidase_sua/sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015883">
        <property type="entry name" value="Glyco_hydro_20_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029018">
        <property type="entry name" value="Hex-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029019">
        <property type="entry name" value="HEX_eukaryotic_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22600">
        <property type="entry name" value="BETA-HEXOSAMINIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22600:SF26">
        <property type="entry name" value="BETA-N-ACETYLHEXOSAMINIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00728">
        <property type="entry name" value="Glyco_hydro_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14845">
        <property type="entry name" value="Glycohydro_20b2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00738">
        <property type="entry name" value="GLHYDRLASE20"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55545">
        <property type="entry name" value="beta-N-acetylhexosaminidase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="96"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-hexosaminidase eukaryotic type N-terminal" evidence="12">
        <location>
            <begin position="144"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 20 catalytic" evidence="11">
        <location>
            <begin position="333"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="248"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="38"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="48"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR625705-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF14845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0010940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="741" mass="83434" checksum="73396ADE123475DA" modified="2023-09-13" version="1">MSKKNVSHSYTPLSLQDPNESGKIGTTSDKLNRGQEIENPNSDQGRASMSDENSSSSFEMDSIDYLPQRRHLSKFRDISRFGVGSIFNSTHWSRYWVRYLVVACILAVVAILVPLLVIKPWEYHYRLAPVTNDNVKAMPDEQPVWPIPRSFSFGNEKATLTPTFQIKVQSSSNNEPLDPTLYPVLHKAINRCMDRIQIKRSTTIIETNGYPKHSQDASSLSELIIVIDNALAPLEYGMDESYLININNQPGPQPNQESSTVHEELKRQKRAPTKEAIAVLKANTQFGVLNGLETFTQLIVATPGSGTLVPGQTVENTLEIPNVPWQIQDEPHFSHRGILLDTSRNYFPVKDILRTLDAMSVVKLNVFHWHVLDQQTYPLVSKSFPDLTAKGAQRPDYVYTEHDVATIVQHGEELGIRVLPEFDSPGHAASWGRSYPNLTVCLDAQPHQKYAAEPPAGQLDPLEPFTYTVLDSLVKEWTAQFPDKQAHMGGDEINFDCWKTSDRLRDYIEHADRRAQYENALLPTLTNAAPENNMRRTTSGKQSGEDKLLEVYLNRTFGMFLAQGKRPIVWEELALEHNLALPDSAIVQVWKNAANAKKVIAQGKPVILSSSEYWYLDCGAGQWLIGAQGHSWCQFASWQRVYSYSLTDQFNVEQQKMVYGGEVCMWAEQTDSSNLDSNLWPRSAAAAEVLWSGSRDEQGNERPLMDAAKRLAAVRDRLVQMGVTAAPMYPSYCRHHPEGCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSZ2</accession>
    <name>A0A9P6MSZ2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_000645</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001138">
        <property type="protein sequence ID" value="KAG0011491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSZ2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055496">
        <property type="entry name" value="DUF7068"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46312">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46312:SF2">
        <property type="entry name" value="NUCLEOTIDE-BINDING OLIGOMERIZATION DOMAIN-CONTAINING PROTEIN 2-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23238">
        <property type="entry name" value="DUF7068"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05729">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50837">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NACHT" evidence="2">
        <location>
            <begin position="180"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0011491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="549" mass="62909" checksum="8548E92880D54A66" modified="2023-09-13" version="1" fragment="single">MTRDTAQKRQYHTQKASSGREQAIGDHPVNAQEPLLSERSLKRKAPHNFPAGRETPTKSAKHISSPIPDNQATSTSASSPTLLSFNHVKAALQTYYEPHLNIKRVSGDTLSLESCYINLAIVEAPDQRRKDKKELEAQAAAFHRMPSYEEIYKTNMEEPIPLKELFDKRKLRDGREDVPKTILIQGRAGIGKTTLCKKVVNLYQNGLWRDRFDAVLWLPLRQLKGFRARDIEDLLRKKYFAQCPDRERKMFVSLLAARARSGKVLFILDGLDEILTDTQKNGGDALEAFLKHLLRQEHVVVTSRPSGVDNSTLPKLDIELETVGFSTQNVSDYIINVLTPDYARDVQDFIKRTPSIQNLVNIPVQLDVVCYSWDSLSSNEQSIAMTGLYQTMIRKLWRKDIEQLQKEVGTSLTSQQIQRLSSYQIDKLMATVSEYLSFLAFKGIHNHQIEFDESTLQKAMEELDEFRKRVNQEHLPYQLLDTLKRTSFLHTADAELDTGKDDPQRAWYFLHLTFQEYFAASWIARHLQVKQKSPKPSSAPMMTVEETKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTY5</accession>
    <name>A0A9P6MTY5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RNA helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">MRH4</name>
        <name evidence="8" type="ORF">BGZ80_011386</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000909">
        <property type="protein sequence ID" value="KAG0012964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTY5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47960">
        <property type="entry name" value="DEAD-BOX ATP-DEPENDENT RNA HELICASE 50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="6">
        <location>
            <begin position="338"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="7">
        <location>
            <begin position="601"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="94"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="470"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="668"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="140"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="470"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="680"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0012964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="779" mass="85157" checksum="DF67393289D2A4F1" modified="2023-09-13" version="1" fragment="single">LQSLLRNSAKASPSLLSHRAYYTFGRNHTFLLSSSFRPHFPTTPTLAQPTFKQHFSTSWPAAEYAKRTPRPKQRLVKEQKLKASWKSASKLSKQSVHKAKFGGKTPTPEQVVRSKTRQWKVDDNTKGSSSSSTLHRKRIASTSVSVTSLEKGSRNPQFEHSFAPGFASVYRPKNVRNGPPLKTGNAGRDKAAAAERTLIEAGAKRKSAPNVRGFVPVRFALKPIASDVNLNLVSNRKMPLSKYKLYAQSESTGATTESKEEIFAKTENLKDILERVANSRFQDMGLHPDVEKGIVELLANTTARGSSKASASPVVTEDASTANVKPSEIQALTIPASIDPHKKSPYTLCAAETGSGKTLAYLAPVLHQLKVQEDDAVRRYQSEGGIDEEGSKVRALNTIRQFNQPRAIVLLPSRELVSQVAGILKELSHSIKLRTLAISHAMTPKSIIQRLSSGPVDIIVATPTSLLDYLPKDADQRSGSGRDSRRRDEEERRVRGSASLFDENRLSLDSLIHLVIDEADSMFDRGFGDDVSKIVKQAKAVTSAGGPVKITVVSATLPKKVSDTLDETLPGMLKITTPSLHKSLPGLHQTFLDLKPYFGNRPKAILDILAKQQQVEGSRGKENTLIFCNTKHSCEILYEHLKTNKVPGLLGVLHGDATDRDEILEKFTNDDFIPPPPPQSSSSSSSASSNSKATAFASKSYRGGKILISTDIASRGIDTTAVNHVVLYDFPVTIVDYLHRVGRTARGGRGGRATSLVGRKDRNLAERIMMGIRLGKVLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUJ6</accession>
    <name>A0A9P6MUJ6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_010662</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000768">
        <property type="protein sequence ID" value="KAG0014070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUJ6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0014070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="50" mass="5247" checksum="4CFB9BBA39799645" modified="2023-09-13" version="1" fragment="single">DTPSKDPAATSQEDLKAIDLLATERLIAVYGSKNAAPSAKTASTKWVESV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUQ3</accession>
    <name>A0A9P6MUQ3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein kinase C</fullName>
            <ecNumber evidence="2">2.7.11.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">PKC1_4</name>
        <name evidence="19" type="ORF">BGZ80_011072</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.13" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010000845">
        <property type="protein sequence ID" value="KAG0013446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUQ3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004697">
        <property type="term" value="F:diacylglycerol-dependent serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20822">
        <property type="entry name" value="C1_ScPKC1-like_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20823">
        <property type="entry name" value="C1_ScPKC1-like_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05570">
        <property type="entry name" value="STKc_PKC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000210">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000103">
        <property type="entry name" value="Protein kinase C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046349">
        <property type="entry name" value="C1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011072">
        <property type="entry name" value="HR1_rho-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002219">
        <property type="entry name" value="PKC_DAG/PE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017892">
        <property type="entry name" value="Pkinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24351">
        <property type="entry name" value="RIBOSOMAL PROTEIN S6 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00130">
        <property type="entry name" value="C1_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00433">
        <property type="entry name" value="Pkinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02466">
        <property type="entry name" value="Tim17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00109">
        <property type="entry name" value="C1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00742">
        <property type="entry name" value="Hr1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57889">
        <property type="entry name" value="Cysteine-rich domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00479">
        <property type="entry name" value="ZF_DAG_PE_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50081">
        <property type="entry name" value="ZF_DAG_PE_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9 19" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2" evidence="15">
        <location>
            <begin position="296"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="domain" description="Phorbol-ester/DAG-type" evidence="17">
        <location>
            <begin position="501"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="domain" description="Phorbol-ester/DAG-type" evidence="17">
        <location>
            <begin position="567"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="16">
        <location>
            <begin position="830"/>
            <end position="1090"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="18">
        <location>
            <begin position="1091"/>
            <end position="1158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="413"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="632"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="676"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="723"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="132"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="751"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="433"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="636"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="660"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="686"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="725"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="859"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAG0013446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1158" mass="130951" checksum="8C3564BCAE9372F5" modified="2023-09-13" version="1">MSASEEVVYHAKAPIKEGLQAGAIGAGVGLLVSAVQNSIGSHSQGATGVIARTGGTIGVFAAMAGVFAATDSAVANVRETKDAWNSVAAGCASGLVAGGFQRNAQTMVFGCVGMGAMMGVFDLSGTSLKIIKMNDEQKLEDLRKRLERENEILIATRNIRKIQQSEAAKATTDATIEETQQRIEYFQNEMNKLLSKVLDNSQGVNNASSNSIGSLHPHQSSDDLLKSSRIITTNKVVYKMHELAYKLDVEKKLKLASEKLEQLGMNAKDGNEESAEKVILLKRALQKYQGLYIPGQDGDDSPGTAPRRPMTGLLQVRIAGIKHQSNAPTRDARPAESMAVIKIDGALKAKTRMARNGPQGIRWNEDFEIPVRKASEIEITVYDRPEYTAIPIGMFWLKISDLVEELRRRKVEADNDAARSAQDVQDLAVKSPGSRQGSLAGGETSTNGVDGVDAWWDLEPTGQIGLKFNFVKDVAVRKRPSKLGRQGAVRKRREDFQEIQGHKFSSQKFYQIMCCALCNELFTGRGAQCEDCSFTCHTKCAEKVFIKCISSNMVEDPDEAKLNHRIPHRFETFINLSPNWCYHCGHMLTFGRRHKTCTECPVFAHEGCSDLIPDHCGMPAETANKLMEEIRRRNQTAKAQKTSPDTKRGPQTTVPALEGEQAHGHTEDRLKQDMEKLQLQQQQESEQQRLAEEQRKQQQQQQKALLLQQQQAYQQQLQLQHQESDSAYKQASEQAVPAQSSRPHDNDLFRREQQRLELLRLEQERTKQYQQQQQQQQQQQQQQQQQQQQQQQQYQQQRPFPVMPKPHTPTLKIVNKQSTQPARKIGLNDFHFLAVLGRGNFGKVMLAEDKKGGELYAVKALKKDSIVQHDEVESARSEKRIFQIANKERHPFLTTLHSCFQTETRLYFVMEYVRGGDLMMHIQRDRRFGERRAKFYGCEVLLALQYFHQNDIVYRDLKLDNILLTLDGHVKIADYGLCKENMPYGTTTRTICGTPEFMAPEIIEEQPYDRSIDWWTFGVLMYEMLLGRAPFSGEEEDDIYDSIMDDEPMFPQGFGRNEQALLQSLLMKVPHLRLGAGPGDAEEIKAHAYFRDVNFDDVYHKRIPPPFLPKVTSAKDVSNFDPEFTRESTSETPTDYRLNHVEQGVFQGFSYVSPWLQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MV44</accession>
    <name>A0A9P6MV44_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_011099</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000850">
        <property type="protein sequence ID" value="KAG0013414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MV44"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0013414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="444" mass="50475" checksum="A93748FAE8A816B5" modified="2023-09-13" version="1">MSVEPIYLGSDVFEPNEVKGVHTFFQKHEVAKWTATSFLSEYPSDLKEFSESLDLIVSVKSVGRPIRTYCYKIMQFLDSIEGQTHIRILQAQSRTSQNSTLIRENTFEAFQKDIIDDQTAKLKARHAKRARQESSVPLSPTRNETKGTESRYSTEEPWHSLTHSLMEVRQFHVDIDRVAMSCCLNVMSDRACKHFENHDKDGLLDAARTSSVIEGFELHECTNIAKRYTPFLAENTVEDLKKKLSIDIGALNQKYVNTELPASAKLEEKVLEILKQLDEKALEASKIMRQHQASEYNEVSESARKVDCLFMYEGLELSNIEFKKPDTSVHDLAIQNRKNVRLGRCIQEAHIAVGVQEPSVMMADVAGFVGIFYQVKKMGDIAIAGKTTSTTVALPQDAESFDRFLEDGSLAIMWNFISHLEKQGQKVLRAKQRYDAMSRSTKFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MV48</accession>
    <name>A0A9P6MV48_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">S-adenosyl-L-homocysteine hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">SAH1_3</name>
        <name evidence="1" type="ORF">BGZ80_010808</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000795">
        <property type="protein sequence ID" value="KAG0013838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MV48"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004013">
        <property type="term" value="F:adenosylhomocysteinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033353">
        <property type="term" value="P:S-adenosylmethionine cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1480">
        <property type="entry name" value="Adenosylhomocysteinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042172">
        <property type="entry name" value="Adenosylhomocyst_ase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000043">
        <property type="entry name" value="Adenosylhomocysteinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23420">
        <property type="entry name" value="ADENOSYLHOMOCYSTEINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23420:SF0">
        <property type="entry name" value="ADENOSYLHOMOCYSTEINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05221">
        <property type="entry name" value="AdoHcyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0013838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="69" mass="7438" checksum="A9B1FF71A330DDF2" modified="2023-09-13" version="1" fragment="single">MVFKVADISLAAFGRKEIELAENEMPGLIALRQKYGPQQILKGARIAGSLHMTIQTAVLIETLTALGAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVK1</accession>
    <name>A0A9P6MVK1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_010643</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000762">
        <property type="protein sequence ID" value="KAG0014115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVK1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026508">
        <property type="entry name" value="TMEM164"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20948">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 164"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20948:SF2">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 164"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0014115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="148" mass="17248" checksum="A58223D976396A64" modified="2023-09-13" version="1" fragment="single">MFENLGNLLLAVAAEMPYETDWNSSLKGSWYLSPRRHTVEFFIYNIVFFYATRFFYRRALAPGSRISQEFAKYVPPAKKSKIEISVVVTLLATLLITMVHKYMRGGLIYMLQPCHMSALLLIIILLGPKDKQWPHILLNIYFHIMWGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MW40</accession>
    <name>A0A9P6MW40_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">RNA polymerase II transcription factor B subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">TFB2</name>
        <name evidence="12" type="ORF">BGZ80_010073</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA.</text>
    </comment>
    <comment type="function">
        <text evidence="1">Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the TFB2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000663">
        <property type="protein sequence ID" value="KAG0015066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MW40"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000439">
        <property type="term" value="C:transcription factor TFIIH core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005675">
        <property type="term" value="C:transcription factor TFIIH holo complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001671">
        <property type="term" value="F:ATPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040662">
        <property type="entry name" value="Tfb2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004598">
        <property type="entry name" value="TFIIH_p52/Tfb2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00625">
        <property type="entry name" value="tfb2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13152:SF0">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13152">
        <property type="entry name" value="TFIIH, POLYPEPTIDE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03849">
        <property type="entry name" value="Tfb2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18307">
        <property type="entry name" value="Tfb2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 9" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Transcription factor Tfb2 C-terminal" evidence="11">
        <location>
            <begin position="371"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="444"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="448"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="458"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF18307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0015066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="468" mass="53074" checksum="FDC726D14B88C973" modified="2023-09-13" version="1">MSSLYVDTPIPIEDMKLWFKGSAGLHKHHEAMQRLKALHIFSEEKGCYKMNATFLEQFRNALTGGGDSQSFGLATSTPDKHHVDIAFLDDYATKQWEAILHFMVGTTEGRPPCKGVLNLLGRSGLMTGGSDIPQGDNMDARDFANQMARHDFGVPKITHKGFQFLLQDINTQVWAFLLQYLNMAESLFMDLVEVLTFFFQLGSLELGNDYSSETLTPTQTHLLEDLKAYGIVYQRKRGSRRFYPTRLATTLTSGTPVMLGSHTNAAKIAATAVAARKTEEEEEDDHGFIVLETNYRLYAYTDSPLQIAVLNLFVHLRDRFPNMVTGVITRDSIRRALSKGITADQIITYLTAHAHTQMRKHTPILPLTVVDQIRLWEIEKNRLRPTASWLYSQFSRQQDFESTLQYASEMGVVLWSDQKKRLICVSSDGHQAVGNYVRKLINRHKEQQAQQAQSQQQPHHHHTTSVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MW51</accession>
    <name>A0A9P6MW51_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_009587</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000588">
        <property type="protein sequence ID" value="KAG0015859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MW51"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="505"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="674"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="253"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="336"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="600"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="262"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="345"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="376"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0015859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="697" mass="76617" checksum="92A9B33E11D038EF" modified="2023-09-13" version="1" fragment="single">NPTPIIKKARKRAATTSADTNRPTFAISPSSLEYQLTANLLNYNPSTAAASSASSRPRQKPRRGTVGSDARIDSSKIVATSSQSTGHGHNRSRDKNTVEASSEIYGRNNLQESEQRKRSRTVVERLTPTGSLPSSPKATQDPVGYFPSSDENIEHPAHSTPSIPHPPLPPKSPRSLIAHYFPGPLPPPPSRGRVPTGHKEPLVAPTPFKTPTFGPASVLTSFQDNNAPPMPSPSSSFHYIPLTNNISRCSTAQTHNHEDSDLVSSSRPSPCTSALGLSAPVSKAQQQQLQTHRIPSDLDLLMANNARGRFHNHQHNNFNRNHPINNFSVHNHTLDTNNSNHLHHHTNDDENDDHPAESGEVAFSNPVPGTRRGPITTTATATTTTTATPPTAPIYPRGLMSTAGSPLVEQNNPIVARVQQKAVPYIRELVPGKEPTGPPSSNTSRDLEIIIDKITGRLRTNRTSMEPWPYYDSPWDEKPLPPVRREKGNRYWVFRDVDGLVPGPFFFILGHLLPFLWWIGSVYPLAEHPDDIRALERAQAQAQAAAAAAAAAGNDVDAESNQNLRNDGMIQRLKNQLRKIAGKKQEPIMIIEMARVSQDTDREGSTIAPPPNPNHHLLHHANPADLDNDITQAPPVDTHGPWSAEIHAPSLFEQRLEHDRKVLRYELNQRWKKINLIWSVGSFVIAIIATALVVSFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MW62</accession>
    <name>A0A9P6MW62_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RHO1 GDP-GTP exchange protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ROM2_2</name>
        <name evidence="7" type="ORF">BGZ80_010025</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000656">
        <property type="protein sequence ID" value="KAG0015136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04435">
        <property type="entry name" value="DEP_fRom2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00160">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001180">
        <property type="entry name" value="CNH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000591">
        <property type="entry name" value="DEP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000219">
        <property type="entry name" value="DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041675">
        <property type="entry name" value="PH_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052233">
        <property type="entry name" value="Rho-type_GEFs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46572">
        <property type="entry name" value="RHO1 GDP-GTP EXCHANGE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46572:SF2">
        <property type="entry name" value="RHO1 GDP-GTP EXCHANGE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00780">
        <property type="entry name" value="CNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00610">
        <property type="entry name" value="DEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15405">
        <property type="entry name" value="PH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00621">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00036">
        <property type="entry name" value="CNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00049">
        <property type="entry name" value="DEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00325">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50219">
        <property type="entry name" value="CNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50010">
        <property type="entry name" value="DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DH" evidence="5">
        <location>
            <begin position="631"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="4">
        <location>
            <begin position="852"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="domain" description="CNH" evidence="6">
        <location>
            <begin position="1016"/>
            <end position="1318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="222"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="299"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="379"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="588"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1382"/>
            <end position="1404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1440"/>
            <end position="1466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="31"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="47"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="73"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="126"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="157"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="228"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="299"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="335"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="389"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0015136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1466" mass="163139" checksum="3DC786C35EC9403C" modified="2023-09-13" version="1">MNPNTAQGYPPDFVRGTVRPSTYSLRQDGAMGPGGAGNPGQGMGPGAPGPSMGPRPVRPIPSQQGSGYPIANRFSTQSLSGWEQESYNSSGPVGHHPNVRPPPATWNDPAGQSGPGPGSMNHRRATSTQLQPTYYSQQQELDRHGSIASRYNGGPYQPNSGSSYQPQLQYPTSPNRQLVRHQLSDNPSSPVPRIHNVLPGHSDGYFHPNTPFRKLSISESLDGGRLSMDSTGSLDSTYANRQPTLYPASNMYNREADAEMDTFPPNRQRSASKSSTYSAHSVNSDYYDYADFDSIAVQRSTTPNGGTPQISIQSAQGYPASRADPFSMRARTPSPGRTRQGSNPPMVNRAANPPVFLVTSLPQPESSRRSAEFVRMQPAQPKISRLQGERSQSFSSYSTPTFDPIARQAALPSSASSGALGPPAVRKPPIVYPALLSRVANAFVQRITTSSRIKDSIEYKDCFDGRDAVDKIAFIIKTTDRNLALLLGRALDAQKLFHDVTYDHRLRDSVNELYQFRNNLITGGPRIRSIESREHRPSYSASEPVDDTDAVNGVFTLLTDCYSPTCTRDRLCYSIACPRRLEQQSRLNLTPNGGLKRTLSRSSTKEKKDQRLWITSVPKEVSDGVSSDEKKRQEVIYELIYTEKDFVNDLKYLNDKWITPIRNLDLLPESRREAFIDRVFYNIKDVYNVNSKLGEALLKRQQAYAVIPEVGDIFLEHVVNFSPFVLYGANQIEAKYEFEHEKNTNSAFSKFVEETERRPESRKLELNGYLTKPTTRLGRYPLLLEAVLKYTPDDNPDKKAIPQVITIIKDFLQKVNLESGKCENAFNLRQINKGLQWKGEPMELNLLAKDRQLIMKGPLKKKGTSSEHADLYVFVFDHVLLLTKEKKGKGGEGYKVHKRPIPLELLTLSTMEEPIMKNSRRTSSLIPHKNTSTSTVVSKITPASGPLSKITSDSKSGYPIVFTHIGRYGGSFTLYATTHAGRKNWMDKIQKQIQALKNKADAWRLLPVSERFFTAGNKVNCSATLENGRRLVIGTDTGVFVGRPKGQFTKIIARERVSQVDVLEDERIMLVLAEKHLFAYGLEALDPSDPNSPNKRAKKLGSSVSFFKTGVCQNRTLVGIVKNSSNALNQSSTIKTLEPIEQAGSKKNKHSFRTILRGGNAELFKLYKDFYIPRETNSLHFLRNTLCVGCSKGFELIDLSNLNTQDLLDFSDPTLDFVHKKDENLKPLAIYRIGTGDSFTFLLCYEEFSFYVDKTGRRARNGWIIHWEGVPTFCALSLPYVIAFDPSFIEIRHVETGDLVQIIPGNNIRCLYHLANFPGGIHVVMTDEEGEFQTIAQLCRESEVATILGNSEEDDIPPPYSTASVIEEDEDAYEDEKAGAMLDEEEDESGNYSPTDGAYPHHPSGLNKVVNRLTLDFGEGFDFGCNSPDSPQSFTEILDIGSGPAHSEGSMTSLTLKDEGDGPTYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MW92</accession>
    <name>A0A9P6MW92_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-haem dioxygenase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_009971</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000648">
        <property type="protein sequence ID" value="KAG0015213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MW92"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48420">
        <property type="entry name" value="NON-HAEM DIOXYGENASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48420:SF1">
        <property type="entry name" value="NON-HAEM DIOXYGENASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0015213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="338" mass="37693" checksum="BAA3EB24E0F1B077" modified="2023-09-13" version="1">MTSNPNEVVVIDYQDLVTGVDVSAKIEKAFGAHEHCLGLLLVSNLPKEYLALRERLLKLASTFAALPEEAKDKTVHAASRYSFGWSCGKEIMNGKPDVSKGSYYANPLMDEPESSKDLQEQFPEYCHPNVWPSDDLPELEEAFKELGQFIVEVGKQVAKKCDAFDVIQESKTTKARLLHYYPQTGVTEGEKRDDMDSWCGWHLDHGSLTGLTSAMYIDESKEGLTEVSCPDSEAGLYIRNRGQEVVKAGIPRDHLAFQTGEALQLATRGLLAATPHCVRGATAPEEDPKRYATLARNTFAVFMQPSLETIVTEDGRNFGQWTKEVLDRYYDKEDKGGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWH6</accession>
    <name>A0A9P6MWH6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">PAN2-PAN3 deadenylation complex subunit PAN3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">PAB1P-dependent poly(A)-specific ribonuclease</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Poly(A)-nuclease deadenylation complex subunit 3</fullName>
            <shortName evidence="7">PAN deadenylation complex subunit 3</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 10" type="primary">PAN3</name>
        <name evidence="10" type="ORF">BGZ80_009873</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1. May also be involved in post-transcriptional maturation of mRNA poly(A) tails. PAN3 acts as a positive regulator for PAN activity, recruiting the catalytic subunit PAN2 to mRNA via its interaction with RNA and with PAB1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer. Forms a heterotrimer with a catalytic subunit PAN2 to form the poly(A)-nuclease (PAN) deadenylation complex. Interacts (via PAM-2 motif) with poly(A)-binding protein PAB1 (via PABC domain), conferring substrate specificity of the enzyme complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">Contains a pseudokinase domain. The protein kinase domain is predicted to be catalytically inactive because some of the residues important for catalytic activity are substituted and it lacks the equivalent of the binding site for a peptide substrate. However, it has retained an ATP-binding site and ATP-binding is required for mRNA degradation, stimulating the activity of the PAN2 nuclease in vitro. The nucleotide-binding site is juxtaposed to the RNase active site of PAN2 in the complex and may actually bind nucleosides of a poly(A) RNA rather than ATP, feeding the poly(A)-tail to the active site of the deadenylase and thus increasing the efficiency with which this distributive enzyme degrades oligo(A) RNAs.</text>
    </comment>
    <comment type="domain">
        <text evidence="7">The N-terminal zinc finger binds to poly(A) RNA.</text>
    </comment>
    <comment type="domain">
        <text evidence="7">The pseudokinase domain, the coiled-coil (CC), and C-terminal knob domain (CK) form a structural unit (PKC) that forms an extensive high-affinity interaction surface for PAN2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily. PAN3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000630">
        <property type="protein sequence ID" value="KAG0015427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWH6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031251">
        <property type="term" value="C:PAN complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008143">
        <property type="term" value="F:poly(A) binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000289">
        <property type="term" value="P:nuclear-transcribed mRNA poly(A) tail shortening"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.3700:FF:000001">
        <property type="entry name" value="PAN2-PAN3 deadenylation complex subunit PAN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.5160:FF:000002">
        <property type="entry name" value="PAN2-PAN3 deadenylation complex subunit PAN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.3700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.5160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03181">
        <property type="entry name" value="PAN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030844">
        <property type="entry name" value="PAN3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041332">
        <property type="entry name" value="Pan3_CK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12272">
        <property type="entry name" value="DEADENYLATION COMPLEX SUBUNIT PAN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12272:SF11">
        <property type="entry name" value="PAN2-PAN3 DEADENYLATION COMPLEX SUBUNIT PAN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18101">
        <property type="entry name" value="Pan3_CK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 7" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="255"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Knob domain" evidence="7">
        <location>
            <begin position="538"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="499"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="8"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="284"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="333"/>
            <end position="340"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="400"/>
            <end position="401"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0015427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="631" mass="70587" checksum="0F6E34F2E3E42112" modified="2023-09-13" version="1">MAPPSTVSANGDDTTSNNNSNASNNNAGSSVSATNAWAPKTTAKTSALNPTAKPKLHVNSPIFKPSSLSTSSVKADAINAPEFVPKSAQDNSLAASAYSDRQLYGRKYAQTAVSALWYLERDERNPYAPPIQNNLISSMSNLSNNFSQFGMNDISMPGSIQGSYYGEGSMSGYYYQGSGAMLHQPLQYHLYNTPLPHVSNLLPHQKTIHGFFISDTLREELHRKNEMILQTVSAQEYGLPEELHEYHSLYPLDLTQEKSTEVFGYQSSVYKSMCSVDGRTYALRRIEGFRLTNELAMQTIEGWRRIRHANIVSIREAFTSKAFGDHSLIFVYDYHPCSKTLYDVHFGPQAQLASQVVVGAPKNTDHSIHERILWSYLIQLTSALKKIHSAGLAARLIDPTKILVTGKNRVRLNCCGIMDMLTFDSAPNIAHLQQDDILNLGQLMMTLACKSLTATHNISKSVDYIAQHYTQDLKNMILFLMSQPVPMKTVDQIITMLGPRVLQEINDVQNANDILESDLGRELENGRLTRLLMKFGFINERPEFDMDPAWSETGDRYIIKLFRDYVFHQVDEAGLPVLDVAHVLTCLNKLDAGVDEKIVLMSRDELSCLIVSYREIKACIESAFRDLSKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWQ6</accession>
    <name>A0A9P6MWQ6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_009168</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000527">
        <property type="protein sequence ID" value="KAG0016510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWQ6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045004">
        <property type="entry name" value="ECH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058841">
        <property type="entry name" value="HTH_76"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36855">
        <property type="entry name" value="CHROMOSOME 10, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36855:SF1">
        <property type="entry name" value="PEROXISOME MEMBRANE ANCHOR PROTEIN PEX14P N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16113">
        <property type="entry name" value="ECH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25871">
        <property type="entry name" value="HTH_76"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PEX14-like helix-turn-helix" evidence="3">
        <location>
            <begin position="23"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="PEX14-like helix-turn-helix" evidence="3">
        <location>
            <begin position="97"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="domain" description="Enoyl-CoA hydratase/isomerase" evidence="2">
        <location>
            <begin position="394"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="732"/>
            <end position="782"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0016510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="782" mass="86066" checksum="F5EAD11523CE8233" modified="2023-09-13" version="1">MATDSGIYVQQDSLPFSSEELGAFHRFHAHKWDQDEQFQAGLRTITQAQAASPSTSELLKMKQYYFSTRMDTKINLDNYLAWRRHLEKPSDDPNAPIFKRFDEYDFDNDVKFQKGLPSIIGQLIQDGKSTLDKAALEKEMTKAKAFYYARLIELFDFPAYLEWKEMEKSQAGPACPFAHLWQNKGTGSGNELAEDAQKFLTTTSPVSTGAFKVHLHSPATRNVWTGLRLAKLSQAISHVQSEATVTSILWTVNGGTSSLDQRDPDSMIASRDEKWFTGGIVSNGSAETPSTCDPSKANELLRQYYSVVNQLSDINNKHQKPVVAVVDGIVSLSAAYLVFGSGAQRVITENATLSFTPSESIDPTPNELENPFAGLYLLSLIQSYAKNDTSARPIPKGIAHYLAFCPNYILRGPDLRKLGLADFFVSSSKKKDIEKAVLSVAGCPPPHTTHAIRMALNAEIVYPGPAKIDVWRSEIDECFGDVKSLKEIVANLEKYDNNWSKSIRTYIASLDSVFANLMFEATKKVSELGSFLECARLEYRLIQRYKEYTSSLPENKQDGSHDANLDSFFEPIDGEEDLINFPFAKWIQEHGHEVEFSSVSTTTDSEAQDPTKACPYLASKANDNKVPSDHPSIAGVDMSDPDAAKACPFLSAKNSQGTSSVAPEAVPSDHPKIPGVNFSDPDAAKACPFLSAKKTQENNSAVQHETVPQDHPNIAGMNLSDPEAIKGCPFLSAKHNEKESTPSETGSTPVDHPKIPGVDFSNPEAAKQCPYLASQKASDSAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWR3</accession>
    <name>A0A9P6MWR3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">rRNA-processing protein EFG1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">rRNA-processing protein efg1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_009756</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EFG1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000611">
        <property type="protein sequence ID" value="KAG0015613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWR3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030688">
        <property type="term" value="C:preribosome, small subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019310">
        <property type="entry name" value="Efg1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050786">
        <property type="entry name" value="EFG1_rRNA-proc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33911">
        <property type="entry name" value="RRNA-PROCESSING PROTEIN EFG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33911:SF1">
        <property type="entry name" value="RRNA-PROCESSING PROTEIN EFG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10153">
        <property type="entry name" value="Efg1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="62"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="159"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="99"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="161"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="180"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="206"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0015613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="229" mass="25935" checksum="43C0733FF072E4C4" modified="2023-09-13" version="1">MKVTKTEGNKKFERRVAPSKAPRRLLKKKLRDLERLIKNKNSLKDLPEEVVQETEKKMADVKKQIEALGPEEPAAAQTSTNEDGSSKSKGLKFTELRRAGRRISAFKRQHPNYETSEEESKAMEDLELDLLYIKHFPRDEEYISIYPESPLEDEAQIKTQTEIRERIAKARASGELKKPSGSSEGSVAEEAPKAVTGKHPVSNWSDESDESDDEEGEEDTKHGQARRTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWV6</accession>
    <name>A0A9P6MWV6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_009565</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000585">
        <property type="protein sequence ID" value="KAG0015889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWV6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0015889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="134" mass="15043" checksum="776B5A661B19C7CC" modified="2023-09-13" version="1" fragment="single">TRSLLEARKTIADSLQSMINLCKNETTRNAFRFDKTPVPPSLIDKPRQKLEFVILVNLVPLLAVPSLSSIHRDFVVNALQVVRHALSLSEDESAFIAAPGTLQRTKAFNRAILGILKVQGPKFSLRLSRQDEFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MX78</accession>
    <name>A0A9P6MX78_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BD-FAE-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_009211</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000530">
        <property type="protein sequence ID" value="KAG0016484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004061">
        <property type="term" value="F:arylformamidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049492">
        <property type="entry name" value="BD-FAE-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF33">
        <property type="entry name" value="KYNURENINE FORMAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20434">
        <property type="entry name" value="BD-FAE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="BD-FAE-like" evidence="4">
        <location>
            <begin position="121"/>
            <end position="353"/>
        </location>
    </feature>
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    </feature>
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        <location>
            <begin position="551"/>
            <end position="571"/>
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    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="582"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF20434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0016484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="582" mass="65170" checksum="5777CB4C487089D1" modified="2023-09-13" version="1" fragment="single">MPNTYSRRQRMWLAFVASFFLPVWIALTYAPQSYPFLPYHPIRVYKVVSTYATLQFNKLMRLVPLFGHFARFQITNSKKTDMIKNIVYGRGNNLLDVYMCSPAVSSSGHADDDAESDHTVESNGCPVIIYVYGGAWDSGHKSMMMPMAQNLANQGYIVVVPDYTRYPHAKIEEMVRDIQDVVNWTTQNAMRYGGDPTNIYLMGSGSGAHVALLAIMHDAVEQLGGVPAPSVEGDETPLVQLPSWPESESEKQQSILKERVRGLILFSGVFDITFYYAYLHKRGIEEVSAMPRVMHQSANNFLACSPSWILSAATATLERPELLEQVLPKSTLLIHGEHDRLIPAHSSQTLFNLLCAAEIPNTKFKVYTGQDHLDPAIDLILPSNAITAALLGDIDDVIRNSSAANESMNGSFSGSGSNSGTNTPNDGLVEEDRQLLQQQQEKLQQQDLLQKESLGKFKAKELFQARWVCTSLEGLNFPIAGVYSDDDIDSISGQGDWRQELYSQLSQLTSLQKLNVGFKKQIWNREQVIATKTNVGKVELEWMVESWPQLEKNKKDDEAPGSQWWKPRSGYDSELSEKALAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXA8</accession>
    <name>A0A9P6MXA8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_009130</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000522">
        <property type="protein sequence ID" value="KAG0016570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXA8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="124"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="330"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="375"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="467"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="686"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="785"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="843"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="933"/>
            <end position="1229"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="165"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="621"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="33"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="69"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="125"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="375"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="398"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="409"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="691"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="789"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="843"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="981"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1005"/>
            <end position="1040"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1041"/>
            <end position="1055"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1081"/>
            <end position="1102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1109"/>
            <end position="1122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1154"/>
            <end position="1200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0016570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1229" mass="137877" checksum="287FE429B28CAB28" modified="2023-09-13" version="1">MGNSPSSAAQSDSASSGKPSSSNSSKTNKQTQPTPSSSSSSSASTGTAASPARGSHSNIPIMSAVPVSQHLSQQQQQQQQQQQQQQQQPPHHVQQPHYQQPQQQRPLLQNQNRPVSHYVPTTIYQPNQNNQRLQQPSQSRPSSSLSQAPTVNDEDIPTSVLQDQMETMLVEIATTEYRVRELREELDTFESHPKFKEMMVIWLYSFNLGDYNMQNLESLQREALKAWKPVVTTFLQDNSNQGISEIDGQLFDSIINDVISHANMIVGSTLPPEDLIENLIKIAKAELESARKTLEQKRNAFQDCQFTLQARGIIPDSVLQMQRQIEDERKRELEAKRAKEQQEELKAQRLKDLETQRERARRLEELELEQKTKEEALRRRQEEARRNQEELRKKMEAKAAATAASISANRDNQSASHVSGRPKSSTVSAPNEPPLYGSLHNQRMHVESPAAFGVNITEDETILTDNDHEGAQAGDSANHHQGYSGSLPGRYPVDLDDADVPSTPLLRRPRPYPKVPDADADPAGRRKSMYNTHLEASNHPEQQHLNYSSHQTNYQQSHNPIPVAAVHDIQMPMSMPRPFIPDPLQQEYGIGHGHSKGTSQTQDHSHLTTEPGLYPPQIITEQDLQQRLANEQLEMMKKQKEEIEREILRNHEQHRRHTMVNVFQGYGQFSPEEYQNMQAQFPAGYPPFPQPQVFLQQHQQHQQQQQQQQQHGFQHQHSNQQLYPGYSTEYVDNIAQPYNGPALNNQDQHFNQGDFYNYPQYGGYGNQTNSTATANWGQAHQLHPGYVHQQQQQQQQQQQQQQQQQQHNQYTSSLLAAQQQQLLQQQQLQQQLQQQHQEQQQQQQQQQQQQQNLHHQQQNLSPGHQQNGYVDPGAHRNQSNVTYLSSPYASEYDFDPAPSSVDSGVAATAAVATPATPVSASSDGQVYENDASSANVLPQIRANPAKVPVRRAPQAILPEAHSDEASNSQNTKKDEEEDSPESTSLPTSSVEASSVNQTRTVTSRQSDRSLKETTREDSSTGKEGDKAQERTVEKEVKTVEREEEEEEEEEEEEEEVLQRSVRNMRVSSKPAPARTNTGPITSQTPTPTPTQAPATTPSQAPTLSRPLAPSQSPASQQANRISQVFAPFPGQRPPLRAAPRPAPRPAIGGMAKISQESVSMVAKNTQKDVTANTAVVQDSRSSNNDTQADQPSKNPSIVTSENKRPAVPKKPIALRSPPSPTSERSLRIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXC9</accession>
    <name>A0A9P6MXC9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">DNA-directed RNA polymerase subunit</fullName>
            <ecNumber evidence="14">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BGZ80_009237</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Forms the polymerase active center together with the second largest subunit. A single stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol I. A bridging helix emanates from RPA1 and crosses the cleft near the catalytic site and is thought to promote translocation of Pol I by acting as a ratchet that moves the RNA-DNA hybrid through the active site by switching from straight to bent conformations at each step of nucleotide addition.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 14">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Component of the RNA polymerase I (Pol I) complex consisting of at least 13 subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the RNA polymerase beta' chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="14"/>
    <dbReference type="EMBL" id="JAAAID010000534">
        <property type="protein sequence ID" value="KAG0016430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02735">
        <property type="entry name" value="RNAP_I_Rpa1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01435">
        <property type="entry name" value="RNAP_I_RPA1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.40.20:FF:000019">
        <property type="entry name" value="DNA-directed RNA polymerase II subunit RPB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.390:FF:000005">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.180:FF:000003">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.860.120:FF:000006">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.180">
        <property type="entry name" value="RNA polymerase ii"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.860.120">
        <property type="entry name" value="RNA polymerase II, clamp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.100">
        <property type="entry name" value="RNA polymerase Rpb1, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047107">
        <property type="entry name" value="DNA-dir_RNA_pol1_lsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015699">
        <property type="entry name" value="DNA-dir_RNA_pol1_lsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045867">
        <property type="entry name" value="DNA-dir_RpoC_beta_prime"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000722">
        <property type="entry name" value="RNA_pol_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006592">
        <property type="entry name" value="RNA_pol_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007080">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007066">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042102">
        <property type="entry name" value="RNA_pol_Rpb1_3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007083">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007081">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044893">
        <property type="entry name" value="RNA_pol_Rpb1_clamp_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038120">
        <property type="entry name" value="Rpb1_funnel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376:SF11">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04997">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00623">
        <property type="entry name" value="RNA_pol_Rpb1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04983">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05000">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04998">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00663">
        <property type="entry name" value="RPOLA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 14" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 14" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 14" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="RNA polymerase N-terminal" evidence="16">
        <location>
            <begin position="379"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="260"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1369"/>
            <end position="1477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1482"/>
            <end position="1501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="265"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="279"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="15">
        <location>
            <begin position="303"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="1370"/>
            <end position="1386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="1387"/>
            <end position="1396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="1404"/>
            <end position="1415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="1440"/>
            <end position="1451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="1452"/>
            <end position="1473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00053996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU004279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0016430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1722" mass="192976" checksum="523DFD223DD0F318" modified="2023-09-13" version="1">MNIAKPNGTEVTSVAFSLYDAEEIKQISVKQIVNPVLFDNLNHPTKGGLYDPALGPFSKHHVCATCSLDHFSCPGHFGHIELPCPVYNPMFFPQMYQMLRSSCLFCHQFRMSRSETHRFIAKLQLLNKGRFLESKDVDAIPVVGKKSKRGESDMDVDGEEEVLGEDEYIAKLDAYVQKCLKKSTYGHEDYKTTVVNDERKRVIAEFYRRATNKKKCDNCASFSPTFRKDGYAKIFEKPLTKKQQLYNTAQGRVQTNVLATPIKKATSASDSESASSEHTEDEDENNEDDDADMSSESEEDAKKKSKKTKATKTKKSRNIVDSDDEDAMELKDNNKYLTPLHIRNILRRMFAVEQQMCSLLYGANGPQMQKKYSKVVQADIFFLEILPVAPTRFRPASVMGDKLFENPQNQHLGKILNTCERIRDLTSTSKTDEAALKNDRHNSFKYLIDAWIQLQHDVNSLIDSTKNPTIMRGGKQPPAGIRQGLEKKEGLFRKHMMGKRVNYAARSVISPDVNIETNEIGIPPVFATKLTYPEPVTHYNVKEMRRAVINGPSKWPGAAYVQHEDGALSSLANLSLESRIALANQLLTPQDSHSGVSTTSPYPTRTQPTNKKVYRHLRNGDLLLLNRQPTLHKPSIMAHKARILPGERTIRMHYANCNTYNADFDGDEMNVHFPQNEIARAEAKLIANTDSQYLVPTSGAPLRGLIQDHVVAGVWMTIRGSFFDRAEYQHLLYGALRPEIDNTGNGKILTLPPTIWKPVPLWTGKDVITAILHNLTIGRPPLNMTAGAQVKAQYFGKGGEEESIVQIMDGVLVTGVLDKSQFGAKSYGLVHNCYEIYGGDIAGKLLSILSRLFTRWTQRWAFTCRMDDLRLTPEGDKWRRDLQNGGKDIGTKAALKYTKMDCTVEQVRSSKRLQKEFKNKLEVVLRSDEQLAGLDATMKSTVNELTTSVQNACIPNGLLKKFPDNNMQTMTVSGAKGSYVNVTQISCALGQQELEGRRVPIMASGKSLPSFAPFDTSARAGGYIAGRFLTGIRPQEYYFHCMAGREGLIDTAVKTSRSGYLQRCLIKHLEGLKVGYDQTVRDSDGSILQFHYGEDSLDVIKQAHINQFKFSAENSLALIAKYRPAQVLPLLDQTEAMAYNKKVARKPHKYDPTLSLFSPSSYVGAVSEAFEKKLNEYVEKNPDGIIQNPDGPVTKKSERFKGLDKKKFKAMMYLRYMNSLVEPGEAMTLNTFHFAGFGAKNVTLGIPRLREIVMTASTKLKTPTMTLNIKPGVTDSQLQSFCQDTSRLTLAQLIDNVQVTERLISKSSVNNQKRYKVFAVRLNLFREEEYREEYGVTSEEVEDVIERQFVKKLETAILRDIRRVYRKTKGAGEDDIGKPTKAKDTDGGDDEVDDGAEVSRQDAGGEESDDGDGDATSEKISKRGKQAASYEEPDSDDEEVIKAADKAQKELDGEDSEVSTDSSDDSDDEVEDEADKRKRLAREAKQAEKRGKMAEENRRDREERILATSPYVKKYSFDSEEGSWCEIEMHFPADTKKLLMVNLVTAVAPVCIVHEIKGIERVFMSEDETGKPQVATEGVNLKGIWDYSDIIDVNSIYSNDIGAILRTYGVEAARSAIIQEISGVFGAYGIDVDRRHLTLIADYMTFESGFKPFNRMDTESSTSPFLKMSFERTCHFLTQATLHGDFDGLESPSARLVMGKVVEGGTGAFDVMQPLVPETMDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXQ9</accession>
    <name>A0A9P6MXQ9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_009073</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000517">
        <property type="protein sequence ID" value="KAG0016616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXQ9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="22"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="117"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0016616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="216" mass="22417" checksum="EEA8F43A16B79454" modified="2023-09-13" version="1">MTDVAAHAEPHVEVDVSAQPVEENTAAAEQEATFSTAVEPSDAPVLNADDTPLEAAVVEETTTTEVTEVAVAAEAEGEEAPPTSNGSDKKSKSWIAKLTSNIKKLADKKPKAEKPAATDAETPAATEDAAAPAEAEAEAETEAVAETTVTETVVVEESPVPVVVEEAAPAAAEAPAAEEKPQTTGTELTVEEPAPQKLGKRLSFNFFKKSNKADKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MY09</accession>
    <name>A0A9P6MY09_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Calpain catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BGZ80_009119</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000521">
        <property type="protein sequence ID" value="KAG0016576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MY09"/>
    <dbReference type="OrthoDB" id="424753at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004198">
        <property type="term" value="F:calcium-dependent cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00044">
        <property type="entry name" value="CysPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.70.10:FF:000010">
        <property type="entry name" value="Calpain 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022684">
        <property type="entry name" value="Calpain_cysteine_protease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036213">
        <property type="entry name" value="Calpain_III_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000169">
        <property type="entry name" value="Pept_cys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001300">
        <property type="entry name" value="Peptidase_C2_calpain_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10183">
        <property type="entry name" value="CALPAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10183:SF379">
        <property type="entry name" value="CALPAIN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00648">
        <property type="entry name" value="Peptidase_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00704">
        <property type="entry name" value="CALPAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00230">
        <property type="entry name" value="CysPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49758">
        <property type="entry name" value="Calpain large subunit, middle domain (domain III)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50203">
        <property type="entry name" value="CALPAIN_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00139">
        <property type="entry name" value="THIOL_PROTEASE_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="3 11" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="8 11" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Calpain catalytic" evidence="13">
        <location>
            <begin position="95"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="562"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="593"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="active site" evidence="10 11">
        <location>
            <position position="124"/>
        </location>
    </feature>
    <feature type="active site" evidence="10 11">
        <location>
            <position position="282"/>
        </location>
    </feature>
    <feature type="active site" evidence="10 11">
        <location>
            <position position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR622684-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0016576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="637" mass="71870" checksum="21DFEF90382A2C9C" modified="2023-09-13" version="1">MVSKTKKRVSPAAKIAKANKLKEELLRPSVPLVATAAMKAARKACAAKVDAIIAECHENNTKFRDLKFDLLDDFSNCLYSSAVGMHEFERIDGSKRVGDLFRNTVFFEDGATPQDIKQGNVGDCWFMAALAVVSNIPGLLEQLCVKWDEEVGVYGFIFFKDGDWVSTVVDDQLFYTIDPYSFKNKLFFSSCSSERETWLPLMEKAYAKIHGDYQSISGGYTAEGIEDLTGGVSSMIYISDILSKDRFWETEMKNVNQSVLLGCWITHVDGGVMEKNGIQMGHAYSVLKVAEFEGERLVQVRNPWGDVEWNGDWSDDSDRWTPEAKAQLQHKQCDDGVFWMSYRDFLRTFTMIDRCKTFDSSWSVVSNWIPYNVVPRSSGKFEFHTRKGGDTVIVLTQPDTRYFGALVPEYDYQLSFHVYDIDKKLIKRSRRTGVLSNRSVSCEVNLNAGTTYTIIPYISRTANDIRGALKGIEGDFKGNAVLPSQGDENIKVDNEPTKISPEEFMFKQRKVENIRAVSIARLKGQILLGVDDDDHLEQEALKEKSWEITIGLRIYSHDHKATLDGIPGEHPVKTGVSPESEPDTPEAVTATLADKKSDKDGKDNKDGKDGKDDKDDKNDKDEKKIKEKIVSDDHREE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MY28</accession>
    <name>A0A9P6MY28_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">MULE transposase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_007811</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000407">
        <property type="protein sequence ID" value="KAG0017884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MY28"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47718">
        <property type="entry name" value="OS01G0519700 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47718:SF13">
        <property type="entry name" value="OS09G0290500 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0017884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="316" mass="34845" checksum="A83D0CB6EB5CB4CC" modified="2023-09-13" version="1">MSFKEESTFNIPLRCFVAVDSNFKTRLVACVLTCTERTEDFKRILTQLLLSSGGELTSNAQDRTRSSQNIEETGVVAGGFAPKVIMVDEDLAMDLACKTVIPESRIINCKWHIDQNIDKNLRKALGPAWEAFQGRLNAICAALTPEAFETGWNDLKRYLQDNYLDICDPANVDSDEEGNDDKGSGKTKAGGKVGKCLAKLYKQRYHGGGLCISACFTAVNSGLAVDNSPIAKPEDRMKALIAAPMTHIFFESKATQTDDKEETSPKHASLESKVTVTPLDDHDENFCFDEICEAEILDAMNEINGLEESITVQDQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MY74</accession>
    <name>A0A9P6MY74_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Kelch repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_007467</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000383">
        <property type="protein sequence ID" value="KAG0018194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MY74"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23244">
        <property type="entry name" value="KELCH REPEAT DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23244:SF497">
        <property type="entry name" value="WALL ANCHORED PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="325"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="356"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="397"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="416"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="444"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="470"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0018194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="483" mass="51341" checksum="D8D0897BCAE43266" modified="2023-09-13" version="1">MAYATVDESTLYVQMGILPGGTMSTNMFYALDLQSNWNAANPPWKNLVSSSTMQRAPSGFGPSMTVSANKQSLIIWGGFFSNISTYDIETGSWSVNTQSPTNSSPQMGLKAVADPSSGLVYIPSGANQGNNMMEYDPTTGASRSLPMPSEFAGYGLAYYSVVWSTQRSSILLYGGHLITANYSSNEQLFEYKPSINTWSLINTTGQSPGNVENHCAVSANSGAKMVVFGGQNPTTTQLGGIYILDVPSLAWVEGADIGQALSRSNMACTVSGDNFVAWGGDRFGEISEAMGTPVIYNLKNNQWTTQFSLSGAEAVPTGSSNKTKVGVAIGAVAGALAIFALIGYFVFRRIQSGKNSQKDIESSSATGAGGYSEKSPPVNMDIKEGFVSDIKVPIDAAPDSTAPLSQSPASDKEANKQSNLGTSSPRRLSMLSGDQEYLEQLSQLEKRDKSPDRRSNGSQNRRSRTPSVASSSSQSSQQGLLNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYR8</accession>
    <name>A0A9P6MYR8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">15-hydroxyprostaglandin dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_007834</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000409">
        <property type="protein sequence ID" value="KAG0017862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYR8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44229">
        <property type="entry name" value="15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44229:SF4">
        <property type="entry name" value="15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0017862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="254" mass="27516" checksum="B3A1D3F5214280E8" modified="2023-09-13" version="1">MHVENKVAIITGASSANVEFMWSPFHSRAKVILGDIDKQDGSRVENDLNHGKKDKVAYFVPCDVTKYDQIAALFEAANKHFGGVDIIVNNAGIAENCPLWQDDKGVWKKVIDIDLSAVIEGTRLGVEVLTKQGRGGVILNTASLAGLYPQLMTPVYTAAKFGVVGFTRAFKDFPDKSIRVNAVAPSFAPTKIIAPIKDAVTKLGPLVSVEMVTDAFMLLIEDDSCRGDIARITPKYGINVMGRPIPSADKKAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYT1</accession>
    <name>A0A9P6MYT1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transcription initiation factor TFIID subunit 10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">TAF10</name>
        <name evidence="7" type="ORF">BGZ80_006494</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TAF10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000320">
        <property type="protein sequence ID" value="KAG0018974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYT1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990841">
        <property type="term" value="F:promoter-specific chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07982">
        <property type="entry name" value="HFD_TAF10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003923">
        <property type="entry name" value="TAF10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21242">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21242:SF0">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03540">
        <property type="entry name" value="TAF10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01443">
        <property type="entry name" value="TFIID30KDSUB"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="107"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="68"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0018974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="308" mass="32819" checksum="A1DD3C5C01C924C0" modified="2023-09-13" version="1">MSDGSNSSNSTIEDTNMESPSQASGTSTPAQAHNDSDSNMTPARQDTPSNLTPGHVANSAVASPAGAQSVETQQQQPQGSPISSAPSTPSNKAGLVCLPITKAAEPSSSATIASTSTPTAQSSSQPTQRDEQLQQQQNQEQQLLLLQKQAQAQAQAQAHLAQLQLAHAASLGSSSAAVASVAQHNLAVGAALQSRKEEELNRKDRTLAEFLPMMENYNPIIPDAVTDYYLSRTGFDCDDVRIKRLLALAAQKFVSDIATDAFQYCKVRQQSQKRAAPGKEKKTVLTMEDLSDALGEYGINVKKPDYFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZD4</accession>
    <name>A0A9P6MZD4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">D-arabinono-1,4-lactone oxidase</fullName>
            <ecNumber evidence="3">1.1.3.37</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">L-galactono-gamma-lactone oxidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_007655</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; D-erythroascorbate biosynthesis; dehydro-D-arabinono-1,4-lactone from D-arabinose: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.3.37" evidence="3"/>
    <dbReference type="EMBL" id="JAAAID010000396">
        <property type="protein sequence ID" value="KAG0018011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZD4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003885">
        <property type="term" value="F:D-arabinono-1,4-lactone oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2520">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007173">
        <property type="entry name" value="ALO_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010031">
        <property type="entry name" value="FAD_lactone_oxidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006093">
        <property type="entry name" value="Oxy_OxRdtase_FAD_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43762:SF1">
        <property type="entry name" value="D-ARABINONO-1,4-LACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43762">
        <property type="entry name" value="L-GULONOLACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04030">
        <property type="entry name" value="ALO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000136">
        <property type="entry name" value="LGO_GLO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00862">
        <property type="entry name" value="OX2_COVAL_FAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="6">
        <location>
            <begin position="47"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00033418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0018011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="512" mass="57358" checksum="89B4D8C3CCE79D24" modified="2023-09-13" version="1">MLYLIYKDILKGWDGREYSEPSVAPLEKRLLGISTKSHAWSNWAGNQVADPAQIFTPKNVNDLIAIVAQAKAANKKVRAAATGHSWSSTSVVNQDGYLVNVKSMNKIYQPVQGADGTWTVEVETGVTLQELDDILRKHNPPLAVSSNIVIESVRYGGVMSMGCHGAATNARTMPDLVTQVKIVDSNGTLNTFTKDKDPVEFSAATVNLGLLGIIYSYTMEVEPMFNLKMTDTHSLVDDIFSDPKVGGPKLKSMVLNNDQTQIFYWPFNTPLLGASNDHLWVKQWQRTNLTATDNLLKDGLQDVFETLETSLGSNAYSFMALNPASTPFIVPILYQAVSRDTSVVLHAPNAIHYRAGIEKMPCLDVEMIFKVDSNFENVVKAWRYVIDEIYNYAKVDKYPINLTMEMRFIKASSMLMSPAYDEDPEAIYCTIEVLSAVNTKDFSDFSIKMAQYWMDNFQAKPHWAKMWEHVPGIVPYLRQKAGARYDKFEAVRQKYDPNGMFMTGTFAGVLGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZF6</accession>
    <name>A0A9P6MZF6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BGZ80_006565</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000325">
        <property type="protein sequence ID" value="KAG0018913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00160">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000219">
        <property type="entry name" value="DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051092">
        <property type="entry name" value="FYVE_RhoGEF_PH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12673">
        <property type="entry name" value="FACIOGENITAL DYSPLASIA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12673:SF159">
        <property type="entry name" value="LD03170P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00621">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00325">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50010">
        <property type="entry name" value="DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DH" evidence="11">
        <location>
            <begin position="438"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="10">
        <location>
            <begin position="755"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="domain" description="FYVE-type" evidence="12">
        <location>
            <begin position="951"/>
            <end position="1012"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="198"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="375"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="560"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1017"/>
            <end position="1055"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1091"/>
            <end position="1124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1175"/>
            <end position="1229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="35"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="63"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="114"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="198"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="217"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="255"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="273"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="304"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="320"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="386"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1022"/>
            <end position="1046"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1095"/>
            <end position="1109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0018913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1313" mass="142435" checksum="8387A1487B96F211" modified="2023-09-13" version="1">MSNKGAQTIVADPQDMLNGTLPGPRIDASPSIAASTTTTTTTSSSHPPPVHCRPYNIQRRIRQNNGHANGRGNHSPSIRQSWLFPTNRASPSTASETTSVIARSQRPPSVRIEAPSSTSSSATAQSVPPVVTMNHKERRIFSGSARTRLHNIDRMSKMLLNPNAPAPNLLDGPQGFPNPTAPRRARLSLQPAVPVTETLPSSVMATNPSNLPQRTLSTSTTPHTPSSNNYPRHIIVPSTSHHNIEDQLDNGTTDPLSSSLPSSSGFAPGVDTLYNSEYTTTSNSEKSNKHSSMPLPRPGWRLYDLPDHEEPELQHGQGDGSCNNGEERNNFQYSTSNASSTTNLDNHPYAYHAHTRQDSTSTCYTATPNASALDLSSGSGAADPSSMYSPESNLGQAQSPGSFALLPPLPKIVKNTKSPLALRRSSTISSAISSSPSSMFINKGSYVDGLIILQTCFYEPLNAPYATGSNPGMNTATSANLVGGNTTFGSGTGAASLSPHYASSTMGSNSTLSASAAPLLSKKSVGMIFSNFSEILQINIELLTQLENRICGSTLSTGWESDVEEVDEEGCHQGDEGQGSPSTQQADEQKPKQVWVTVGGQGGEQEELLVLDMDWCVGDIFIEIAPFLKMYSNYVKAFESALTHVNECMKSSDRFTEFLKTTARRPECKNLDFQAYFMLPIQRIPRYKLLLESLLRHTPSNHPDHRKLQIAFESMEQTAGFVNETIRQHEMFGEMINLQSKITGMSEPLVVPGRVLLKRGRVWKVCRRNIQLREIILLSDCILWTSPSMNPLEDTLTFHRKVGLENCTVIGAEDPDPTKNAFQIMSSEKSSQVFVDTAKEKEDWIAAIRIATQEYFSAKRTLKPTPTPLENLTSITTGFGLLRRETVLRSPTFGNDSRANTFSIPMCIDPEVAGDGIGTLPSLDNRYQSEKRQQQPLRVVENYNAPVWVPDHSATRCMICTEEFGTFFRRRHHCRVCGKVVCHSCSSRTILIKGTTSEKLGRACDDCFDAMPPEEVNMIDSGISTTGSPESSPVGQQHQQPRGANSNHERHASSQSLDGIMIRSEDYSQESNPSGGATGMVRGFVEAGLSRMKSRSNQPVNQDSNTNDTNPKENTRGSNRNSIDYQNAAHVKECGLCKTEFSMFKWRAEREAKARGIDISAEDAIASLALQNGSSETQDGLAAPGIPQGASESAAEAGTNDGAARPAAAPRSQSFNSDTNNNNNGGYGSFGNGWQRIRGNTDSGHGQAEKLCDPCYLGLSADQIKVLESGGGWQYYQATLGKHHAPGLAAALALSNMSLDDDDGNGNGQQTED</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZK7</accession>
    <name>A0A9P6MZK7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidase S8/S53 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_007114</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000359">
        <property type="protein sequence ID" value="KAG0018480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZK7"/>
    <dbReference type="OrthoDB" id="206201at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase S8/S53" evidence="5">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0018480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="305" mass="33267" checksum="BDCF15461C60B3CC" modified="2023-09-13" version="1">MYGTSMATPYIAGSAALLLEAEPTIDRNEVLSWLQTHSKPGLYRDTSIPDAVSGQGAGMVNNIDGIQGKAFVQPAHLALKDTVHTQESYTITLTNNYDTGETFELSSWPATSILGYTSYGQPTGDVVYNQTSAEVSFAEEDSVYLGPGGTRMYGAYGSVDMLDLQDGYPVLLGPTVDSRLVPILNEAGQSPQVFPMSSNKTVTLVLKISNPLRNLQVYVLNANKKEVLGMVPVDWEYIGWTDSVRSKFFAIHWPGRTIDVYGEVARLPDGDYSLAVVTPKPFSESDNLDDGAHESWVLPVIRIKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0F7</accession>
    <name>A0A9P6N0F7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006318</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000311">
        <property type="protein sequence ID" value="KAG0019095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0F7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="198"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0019095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="234" mass="25773" checksum="F0246F9440D3E2DA" modified="2023-09-13" version="1">MPRTVDTVDVRLTCKIKRQPALETGQECPSSATTTDDAAAAAAVAEHQASQKIITTQETPKGSLEIDVDLTTGEQTSSSSSSSGENTDYLSKKFGFRKHLFRGNTQGYSTPPSSSLHPESETLAQRHRQHRRDMIKTLFLATLDYTNRTLANATMTVPTNMNDTMQDSTTATQDWKDLNLTQLLDVLYHNSSLSVTAPATHSISGTQLGRNFTQEDDGDEAEQIQDRSHPNLER</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0M6</accession>
    <name>A0A9P6N0M6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pantoate--beta-alanine ligase</fullName>
            <ecNumber evidence="3">6.3.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Pantoate-activating enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Pantothenate synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">PAN6</name>
        <name evidence="12" type="ORF">BGZ80_005220</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>(R)-pantoate + beta-alanine + ATP = (R)-pantothenate + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10912"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15980"/>
            <dbReference type="ChEBI" id="CHEBI:29032"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57966"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.2.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; (R)-pantothenate biosynthesis; (R)-pantothenate from (R)-pantoate and beta-alanine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the pantothenate synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.1" evidence="3"/>
    <dbReference type="EMBL" id="JAAAID010000259">
        <property type="protein sequence ID" value="KAG0019817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0M6"/>
    <dbReference type="OrthoDB" id="2020436at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004592">
        <property type="term" value="F:pantoate-beta-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00560">
        <property type="entry name" value="PanC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000013">
        <property type="entry name" value="Pantothenate synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1300.10">
        <property type="entry name" value="Pantoate-beta-alanine ligase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00158">
        <property type="entry name" value="PanC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003721">
        <property type="entry name" value="Pantoate_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042176">
        <property type="entry name" value="Pantoate_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00018">
        <property type="entry name" value="panC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21299">
        <property type="entry name" value="CYTIDYLATE KINASE/PANTOATE-BETA-ALANINE LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21299:SF1">
        <property type="entry name" value="PANTOATE--BETA-ALANINE LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02569">
        <property type="entry name" value="Pantoate_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0566">Pantothenate biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0019817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="314" mass="34999" checksum="8E4C4757DACB62DA" modified="2023-09-13" version="1">MTDITAGEIPVFDSIAAFREWRKEMIRQNKTVGFVPTMGALHEGHLGLVQTAKQECDVVAVSIFVNPAQFAPHEDLDQYPRTFDTDYASLVASKACSAILLPKVSEMYPVGITLDRSQQRGTFVEVQGLSHQMEGIPRPHFFRGVATVVTKLFNIVQPDRAYFGQKDAQQCVVLRAMIRDLLLPIRMRSIPTRREADGLAMSSRNRYLTPEMRNVATLLYRAITAAKEAIIERGVSDREEILAPAYKIIDEVSQEVKAQGLPFDIRLDYLSLVDVETLSELTTLGKSQAAILSGAIYVGTTRLIDNVLINTNEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N100</accession>
    <name>A0A9P6N100_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003031</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000178">
        <property type="protein sequence ID" value="KAG0021098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N100"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0021098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="135" mass="15231" checksum="3F01E29396F4A84E" modified="2023-09-13" version="1">MSTQANNQGADASKNAPRQSDTRVHPQENSTSFTTTDASGYPDKHDGLIAHSTPTVIQDPHEHHKHNQTSKRVQWGHTFHNVLHDKSNVPFYNTLHHKHRHEDHSHGEKPVLGHSISGQLRNHKFPIGTLVEITE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N155</accession>
    <name>A0A9P6N155_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Amino acid transporter transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_003586</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000196">
        <property type="protein sequence ID" value="KAG0020790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N155"/>
    <dbReference type="OrthoDB" id="40134at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF692">
        <property type="entry name" value="TRANSMEMBRANE AMINO ACID TRANSPORTER FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="60"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="106"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="208"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="245"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="289"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="334"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="360"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="391"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="9">
        <location>
            <begin position="29"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0020790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="427" mass="46519" checksum="44ADF467CF97F2DA" modified="2023-09-13" version="1">MEKKETYDANSINSDKESLVDLLAERPEQGSNFLAFANVVCVVAGTGTLGLPYALRVGGWIGAGIVVLSLIMSIYTAILLMKCLYYNGKYRLSSYQEVGRHAFGRVGLIAVWFFHTSIVIGAPVMYLILAGTELKALIPTDALSIKAWVWISAAVVAVPFIAMKTLKEVAVMSVFGALATLVLVIVAVRGSIVDQHNPDYANVGHSGVILANLPTTIASISICFGGNVVYMHVEEAMRYPKSWNRVVATALGTCSLFYLATAIPGYLTYGDKAKSPILENLPDDAFTKVGTVLIIIHVILAAPILLTSFALEFERLVDITVARRGKVMERVYRTIDRLVIIGVVGGIACLVPYFGDFLSLLGALGNCTLIFVLPILCYFKLIGWRHLKWYELIWCAFIVIIGLISAVIGSIDAIKALKNDFQRDNSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N229</accession>
    <name>A0A9P6N229_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001282</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000129">
        <property type="protein sequence ID" value="KAG0021988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N229"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="70"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="179"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0021988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="214" mass="25033" checksum="64D33DB0E3AC761F" modified="2023-09-13" version="1" fragment="single">KELSAAVEKANKELEQQRLQQIHVPETLEPDLIQIPESIASLQAQVEQHRRQVQISYSSVERIESIPREMSTILEMMNDTLEMLEKLQKEALQADSVKSQIEKKRLEASTLETKLKQNERQTKGLEEKLKALNLNQQPRRAQQEAELTDQERIGLEIETKLLESRRVLEERRRKHAEVLQREEKFAQDATAALEKLKHQFECYTTEVLQAMRLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2D0</accession>
    <name>A0A9P6N2D0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Arrestin-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_002783</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000170">
        <property type="protein sequence ID" value="KAG0021253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N2D0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0021253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="527" mass="59201" checksum="ADC17F43D4F4195C" modified="2023-09-13" version="1">MFRRLFNMDGGSNKKSKRLTIYIEPPAQQDYNNNFDDKVQPLIVVRGTREKPGMVEATVTLEVDTACEGDEVEIQFRAVIGSKISVKGGGFSVSLSEQVLQRKRWILPVTKLGPHVIAAGVYSRQVCTMIETNWPSSCTEHSEGFVQYSFHAQITKVSAAKVAMPILTASQEFLVLNLNNSCENYSNYNNYNQYNNFSKFNFHGKENYSKSDISNISYIPRNKHNYSNSCLSNISYSNLNRQNLSNSCLSNVSHNNHNKHSYGMSNVGHNNYNNGINSNAYNIRTKHSFFILPNPTVGVLPGTSTPHSVSVLSPEKSVPIEMSIPSETLVFGQRVPITIAVNPFSEWTPFAGQEIVVMEARFGIEQKRHARSANRIIKDKIVKNFTEIHVPSTRMGSWPQSRNGWKRTVSIKLPAAASFTEKSKPVRPGQHNSPLLLSQSLQSRYYDISHKLIVSLKVRTSGEKDKQAEEIELHLGFQVVHPAPAPDAGEPPTEYRPVAAFSFESDEIPLIFDQMDPRQEKNSQLIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2I0</accession>
    <name>A0A9P6N2I0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Rho-GAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_002708</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000168">
        <property type="protein sequence ID" value="KAG0021287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N2I0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00159">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050729">
        <property type="entry name" value="Rho-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23176:SF134">
        <property type="entry name" value="RHO-TYPE GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23176">
        <property type="entry name" value="RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rho-GAP" evidence="3">
        <location>
            <begin position="379"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="95"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="564"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="736"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="98"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="113"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="564"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="590"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="646"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="754"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="772"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="819"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="843"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="859"/>
            <end position="873"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0021287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="873" mass="95918" checksum="62B320243F063939" modified="2023-09-13" version="1">MSRHSRIPSDAERDNFTPASGGLTRANPIKPQLAIPAMTKEAKESREQTQLWDVSLNKVFQNMHGDDTARFLSYFKARLEIEETYSRSLEKLAASAKGGSRNSNNNNNSNVSGGPGGAGGGSGGGGQGNGGNNSYIDPEEIPTTLRVALDALIDTTQQLHIGRRSFVKLLKTLTSALATLKESHEKQRKSHKETVKPVFQIYAETRLSTVPKLKRAYEQRCRDVEQVLSNEESDHLPVLEKLKNMTSSTGAAGRLLKCKRDMDEAGKCEYKLAVQNLEVYRQKREQFYDSSFQAMQNMINERGTSCHNCLKAYVNGERDIMAKAKEDIDRLSTVVSCIKPSGDVDQISMTFVKDINSHPKQVHYENYYQKNAPVSIFGTSLTEYVRKYNHAIPLVVLKCSEAVDRSGLRREGIYRVSGRHAQIMKLKKQFEQNEESVDLTDPVYCDDSASIAAVLKIYLRELPEPLFPFPLNERIAYSAITDKNMRFGELRARLKRLPDCNIDTLQYLIQHLRRVYAHVEDNKMTLDNLSMIFTPAIFHDFNSAMVTGPQGGATAPGVGDTSLSFASTATSPSSGSPGLQTAPWSAFQPPDQQQSGQLSHQTTQPFFMPQNPTLGYGHGSGPSSPMMIPDPTSSPLSYPQAPGIVQNDQWGNPSSNMAAPKMNPASNIAGSAVTSTSSFTPPSNTVSAAASWSNDLVLADLILNSDTIFNVLPKIPSRSNTAMTIDDRVMAGTTSAFANTSLRPDPNNYAPGRSYSASRKSSSSSLGGNGATPASPTDSSGQLRPRMDSLGPNSSARTTPPVVSPTMGADQYQYHLPTPHQQQQYSYNDVRQAARANTPPSPSSSKGLTRSMSNMDMRQQQQQYQHQYQHQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2T2</accession>
    <name>A0A9P6N2T2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_000034</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000100">
        <property type="protein sequence ID" value="KAG0022530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N2T2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BHLH" evidence="2">
        <location>
            <begin position="40"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="75"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0022530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="251" mass="27935" checksum="6D59ABAA189F9E67" modified="2023-09-13" version="1">MTATSSPTTPPPKNVFRLHGVNVLNRKNVDSISRLTALEKRRTTHILDERQRRDTMNQLLGELANLVRESAAEAQQQQQQQQHQQKQYNPDGTEKKPPVKSNSITTLRNAISEIRRLRACAGLETITPPCAASLVVSSPSVSRSSSPMEVSVSSNSKQQFQQQQHLLPPLAPMAPQYSTSDSRHSAAMATPESYPVQYQQIYGHSLNKTQYRYESPQSFSRPPSPGLSAPMALPQPYIQHSSYQSSPYALV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N319</accession>
    <name>A0A9P6N319_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_001683</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000139">
        <property type="protein sequence ID" value="KAG0021804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N319"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16461">
        <property type="entry name" value="RING-H2_EL5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46171">
        <property type="entry name" value="GH10160P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46171:SF3">
        <property type="entry name" value="GH10160P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="3">
        <location>
            <begin position="686"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="185"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="303"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="459"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="574"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="14"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="37"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="85"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="200"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="221"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="250"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="303"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="359"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="376"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="400"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="487"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="579"/>
            <end position="595"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0021804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="752" mass="80166" checksum="0C1B08CDD4B14844" modified="2023-09-13" version="1">MSNSNADTSRTALNGGNASSGNGRSTVARPERPPSRSGISPTGSPGLISRSSTRSPGLQAPNPTSNGRTPRGLTRVQRMYDEQSIRSTRSSSRASSVIAASPSLNSPSNEASLQGHVVEYMDIDSDTNDIVPHEQQRLSAAQHHNRSHAHNTQTGSAFTEHYHHHQLTSVPSDNAMNFRADQSFARPSITTRSRIRASQEPVSSASSAITGSDNNSFYAGLSNSRGGTSISSSLLPIRPDSDDDDDMENDLNSNATHGGAQTRSRSRRYPDPDVVADLIHHQFVQSLREVNDNVVSSAPAATTTVTTTTTTTTTTVEPFENNSDINNTNNSASVDNAQGRETVAPTSHPNGSVAVDSHTGITSDDTPTTPHRMRLRSSSMRGLLGFQPTEESATDERPVTQDSSSNNTVGADTETQPEGDSRPTNPTDAMDRSQFLLSQLPLFMRLLVDFNRGLRAPVEPVTDDEDRANEVGESASNMEDGSPGLDTANTSGTDNASNQTLDSDTPNPDPAARSRRRHTTIRFIQIGGGLGPSHRARSSSTTAEHENEGDEGDDNQAGQAGEEFGEAVIMLLTGPSSDSDLDTDDSSTPEGSDDAETPRARTRHRSPWVVMTLSGAYLNSLMAAGSGGEGGSNYDDLWMLSNLIGPARPITTTQEAIDNAGFAVGRFEQEAQGMRNISTLGDGTKCLVCMSDYEEGESMRALKCKHGFHLECIDKWLTTGANKCPVCRAAAVSNEPPVLEPQVQVNSGAGDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3M7</accession>
    <name>A0A9P6N3M7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_011586</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000095">
        <property type="protein sequence ID" value="KAG0022641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3M7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="91"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="269"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0022641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="306" mass="33412" checksum="4E715B4D1732E537" modified="2023-09-13" version="1">MYGNNCLLIPVLANSFISNSNQSIFALYQDDNCQSYLYSVEASLASLHGAKSLMWVDNDPSQSHTAGVQFTDPLLSDDQNSGTNRSRTLQIAMISFGIAVIFIILGLYLCYVDNKRNQRRGYVPEPDDPTRNRAMAEVSGPGRSVYQYNSHQRSASSTSSIVTYLPPYASNGYEKSGGKFSSVAYPDEAKIANTPSEKKSSRYDLPTSRSRSFSNLTNQVGTGAGLEPGSVQQGRNEGFGYGLGCDLEDSWKRDSKRNSDIILRDAVMTSPHSPQLRPSSAISDDFGQVAGRGGVMNDPKEIYMSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N419</accession>
    <name>A0A9P6N419_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">60S ribosomal protein L31</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RPL31</name>
        <name evidence="4" type="ORF">BGZ80_003727</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000020">
        <property type="protein sequence ID" value="KAG0024382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N419"/>
    <dbReference type="OrthoDB" id="9739313at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00463">
        <property type="entry name" value="Ribosomal_L31e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.440.10:FF:000001">
        <property type="entry name" value="60S ribosomal protein L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000054">
        <property type="entry name" value="Ribosomal_eL31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020052">
        <property type="entry name" value="Ribosomal_eL31_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023621">
        <property type="entry name" value="Ribosomal_eL31_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10956">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10956:SF0">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01198">
        <property type="entry name" value="Ribosomal_L31e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01380">
        <property type="entry name" value="Ribosomal_L31e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54575">
        <property type="entry name" value="Ribosomal protein L31e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01144">
        <property type="entry name" value="RIBOSOMAL_L31E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0024382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="120" mass="13829" checksum="70694C32CAD05F12" modified="2023-09-13" version="1">MAKESKGTKRSTIHDVVAREYTIHLHKHVHGRSFKKRAPHAIKAIKAFAQKTMGTADVRLDPSLNKQIWSQGVKTVQHRIRVRLSRKRNDDEDAKEKLYTYVSYVPVTSFKGLETQVCDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4A9</accession>
    <name>A0A9P6N4A9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_000903</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000012">
        <property type="protein sequence ID" value="KAG0024602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N4A9"/>
    <dbReference type="OrthoDB" id="2323998at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040409173" evidence="1">
        <location>
            <begin position="27"/>
            <end position="589"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0024602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="589" mass="64286" checksum="C1577A27FC935161" modified="2023-09-13" version="1">MTMIQPRHVGVFMCIWLACLAVLAQSTSPELEEFQPGVPMKSIPVHRLPRSYAGRKRTLTKFQPKNSIQLRFIEAEKYEYYGSCHHVDMLVELKTDDGNHTVQSLNPFAFQNAVKSFSCSGSPAQINIQLSPEYAQQARRWSMPSTRVFGIVIPHDHVDLKNNPACFSDLSASAKKYTQEHPMETVVKMVKNPQFLDTKNPNTLSLTVVKTDIWSNMNRAQSVQIYHKPIEDMISEVFKKRSTAEQDGPMWDFEHSLSAATENVNSKTTADDVNNVNTDLDQSTVKGYAQASMAWKQTCIKNIFTGKMNCLNWGITQSKISGMTQVNHQAKVSVKANSGNIQTRSVNVENKNKTQPLLTLTKVNFTTPSFNLMAPIPLLGFTVPGVFDMGANVGLGGSVSLDVLVQATKDLLVNTGSSTSCPWVIEWDGSFLDLPTIQFGTCTLPGTPKFASDSSSILRRSDSESILYFGPDPESMPEGKTVSLSARSTGSRETAFVSIGMTVSPSLGMGLKVFGFTALSAGISAPISLGINSNWDTDKTTTCPANHVELNSDGSASLQINGGFFGFSKSIPIVQGPTLTTPSTCVPHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N650</accession>
    <name>A0A9P6N650_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Vacuolar protein sorting-associated protein 27</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">VPS27</name>
        <name evidence="15" type="ORF">BGZ80_003089</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Component of the ESCRT-0 complex composed of HSE1 and VPS27.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Endosome membrane</location>
            <topology evidence="1 10">Peripheral membrane protein</topology>
            <orientation evidence="1 10">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the VPS27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000018">
        <property type="protein sequence ID" value="KAG0024421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N650"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033565">
        <property type="term" value="C:ESCRT-0 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032266">
        <property type="term" value="F:phosphatidylinositol-3-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043328">
        <property type="term" value="P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16979">
        <property type="entry name" value="VHS_Vps27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017073">
        <property type="entry name" value="HGS/VPS27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003903">
        <property type="entry name" value="UIM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002014">
        <property type="entry name" value="VHS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47794">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47794:SF1">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00790">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036956">
        <property type="entry name" value="Hrs_Vps27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00726">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00288">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50330">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50179">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0967">Endosome</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="VHS" evidence="14">
        <location>
            <begin position="19"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="FYVE-type" evidence="13">
        <location>
            <begin position="167"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="252"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="349"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="496"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="567"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="620"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="253"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="353"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="378"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="498"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="567"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="621"/>
            <end position="681"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR036956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0024421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="704" mass="77631" checksum="CE111ED60329E67F" modified="2023-09-13" version="1">MSWLWSASPIDELVDRATSENLPIGSEDLALNLEICDQIRSKQVQPKDAAKALKRRLGHKNPNVQLLALGLTDTCAKNGGHHFLVEIASREFIDNLTSILKAPSGCNFEVKNRILGLIQTWGILFRGKHGLGYVCDTYMILQHEGFQFPPKDNIGAALVESEAPPDWTDSDVCTRCRTAFTLTNRKHHCRACGSTFCGQCSSKTMALPNFGVTQEVRVCDGCWMKKKLGPKSVVALESHGLGGGLEYVSGMGSKSATTATSSATKTSSTPASVAAITNTSTNNNSKSDTDAEDADLLKAIELSLKEANNHPGYSAPKRSYTEPVKKTIPTEEEEDADLLAAIEASLRETSIHSSSSTPAPRSSQRQSSYSSYTYSKKPVTNTVSSNELTDTEKSNIEMFSVLVDRIQMMQGDVAGNREVQALYEQISKLQMKVALNLEEAARKQQEFVTFNEKIDHAVRIYDHLLQERLNSSYQRRLNSNNYGNQGIMTQPDFRAGFTQQQQQQQQQQPYQYQPTQPQQPSGTASFAVTSPGPVQQPPLQNQYPYQPQLQQQPQQPNGVVMPVSAPAQVNGQLPTPNNVYQQPSGQTVQSPPPEQQQQQQQQQMAPTLSGPVIQQAPYVPYDPQLQQQQQQAPVAQQFSGQQQAPATQPFSGQPPVTQQFPAQQQFAPQQQQQPIQSVQPIQPIQQQSFAIAQPKIEEAPLIEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N6W6</accession>
    <name>A0A9P6N6W6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003711</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000002">
        <property type="protein sequence ID" value="KAG0024852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N6W6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="305"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="440"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="39"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0024852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="653" mass="72988" checksum="FAF4E0E0B136D4FE" modified="2023-09-13" version="1">MNQMKKKLGLPLDNLPTVGNTSLPATQIASTSNSTSRAFSNNFVNTSNSSSSSNNNNVNGTSKNLWSNPQTAVRAQDSIPSTTSTNGSIWSAPVVVNDTPNPWKSFKPHQSTSPEPDLRLQDERDDYMRTLEEQQPQWDFHQDMEMDDIGLPGNDVDWDAGSNLSMDDARQDLDRKIKEVSPHLADTKLPLKRGLQVRRSLSLKSPFSRQQDRRRADSLEVDTSSPMDHKASNNGGSDGDMDMSRESPCRGIFDTNDLSQEIDKFDIKIERVADISRKSSPGVISSSNVGQDPGRFERLIDAEMQSQRNADKTRGSKRRVSPEYDSGDQDYSTNRRRSRSFVPSPHIEGDDDQIKVKLEKYNDPLLNIKKEVDKFVLGRYSRAEEIIPREPSDEFSRNPVVADDTPFSDSDMQSVNIKIEKTEIKKSDGASYHAAIELISDDDSDDNNSGGKFPSPDQDISEPDIRMKIKSEPDSTSFIPKKVIVKSEPETTYSQSYVSQSKVYIKQEETLLEFDMDDDCDFGGLTEVVHVVPEVELDKVETSVREGKEVKAQARVHKLGKFSLTTLAVSIPITLLPVVSSPRGENPTTEGITPAILTDSKVEAVLDQPVVELLLDYSITQFRELVRVNEPEARKVKTTHKGFMGIHLEEMVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SRQ1</accession>
    <name>A0A9P6SRQ1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_007887</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004121">
        <property type="protein sequence ID" value="KAF9994233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SRQ1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050231">
        <property type="entry name" value="Iron_ascorbate_oxido_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47990">
        <property type="entry name" value="2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="2">
        <location>
            <begin position="33"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9994233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="209" mass="23319" checksum="8D290B8AF79EB520" modified="2023-09-13" version="1">MNQLENLSHTIMEAVALSLGLKASYFRDLFGETPYYRLKCAKYPSVNKAATIGCGAHKDTGFLTVLFQDMVGGLQGQDPATGQWLDTKPIPDTFIVTMGEAIEKMTGGLYHATVHRVLNNTSGRDRYSIPFFFDPSLNARIPFEIENLDTSAELDYTTAKQDQVDELVHSLSTSSIDDSTSQGWSSGAHIFETVHRCHPEVYARWYNKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SRY6</accession>
    <name>A0A9P6SRY6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Alpha subunit of the F1 sector of mitochondrial F1F0 ATP synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ATP1_3</name>
        <name evidence="11" type="ORF">BGZ80_007684</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003982">
        <property type="protein sequence ID" value="KAF9994821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SRY6"/>
    <dbReference type="OrthoDB" id="9805536at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18116">
        <property type="entry name" value="ATP-synt_F1_alpha_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.20:FF:000001">
        <property type="entry name" value="ATP synthase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023366">
        <property type="entry name" value="ATP_synth_asu-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005294">
        <property type="entry name" value="ATP_synth_F1_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036121">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48082">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT ALPHA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48082:SF2">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT ALPHA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50615">
        <property type="entry name" value="N-terminal domain of alpha and beta subunits of F1 ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0139">CF(1)</keyword>
    <keyword evidence="4" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATPase F1/V1/A1 complex alpha/beta subunit N-terminal" evidence="10">
        <location>
            <begin position="63"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9994821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="114" mass="11995" checksum="95FD7DD44AAB603A" modified="2023-09-13" version="1" fragment="single">MLRSLSRAARPAAIALARSTPVVRANVGAISAIRNYATAKPATSEVTSILEDRINGLNSSVDIQETGRVLSIGDGIARVYGLKNCQAEEMVEFSSGVKGMAMNLEADNVGIVVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ST49</accession>
    <name>A0A9P6ST49_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006617</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003276">
        <property type="protein sequence ID" value="KAF9999192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ST49"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9999192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="482" mass="54839" checksum="3C1FCE59BB0ACB05" modified="2023-09-13" version="1">MAECYSSAGAPLNALANQLLGESSFSAKSSPFRPGQQHQQHHQHQQQQQHLQQHHPQHLHQRQGLFPRYVPQQQKPGIDTIDSFEQAWASSSHSAFNHHQQIPSSNFAVPEQYRQFQPQRHIPDLDLISAWEQQELMQLKQDHADGQLHKVQTTASGVTTASHPEFSTLEFEIFTYTPATTEDIHNTGDSAWAQEWSRHKGVETDEDEDDDEYREEWSNDYFTQAYISSHQSKFREIEEQDRLKEARLEEEREKQRQASGGPPRSAWMMAGAVATVTETAGASMYDPKRLRVPGLDSFEHSQSQQDTAFSVDEFMGYSYYDNNIDPQIQQSVQQQQAPKPTRSDDRFLSLVSDLHMAEQIYYPGATSATLPELSEMDPENILTASTSAMQPPTSTGGWAQEFAVEDRQRQQKQKYMGAEWNWEKLFGKDPRRQASSTLSSRNDVEGTVVDENDRLRAVALTRLQALFGHLSLTSPQGPNPTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6STF0</accession>
    <name>A0A9P6STF0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_006389</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003153">
        <property type="protein sequence ID" value="KAG0000303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6STF0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040154043" evidence="2">
        <location>
            <begin position="23"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="179"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="199"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0000303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="210" mass="23320" checksum="1484E110EA487E8A" modified="2023-09-13" version="1" fragment="single">MKFSATIASLIVITVAVLTAEATPVELKKKSRKKCNIDCSGLTLDLINIGAKLFIRDRIGSAIALYRELYYDIGNDVHASRNVEFPEVLLFLLRVSSIAWNSSSYSSNKLHLLMGQLAQELGENAYHRSDDENEKVESDEEEEESEEEEEEESEEETNDGTQESEELPVPIGKLSLANLSQLDQQSGSGSRDNSNPGSDNDDEEDEENDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SU43</accession>
    <name>A0A9P6SU43_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005920</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002917">
        <property type="protein sequence ID" value="KAG0002736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SU43"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="224"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0002736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="373" mass="41243" checksum="0A9D2EB9FF0D6957" modified="2023-09-13" version="1">MRSFVRGAHWVEGVSGVPNMDHMDIYQLPGFRRSDDEYDLEILSDLQVHQYFKINHAREWHPLHYILSPNATTVQAFLDNLKTIAKLQRPPGAYAKSLMRYLLNDNNGKVLMTEAITALEMHRAAVENQMVFSKIQAQFSKDALKGISASADGRSASATSFNTQPSMSPQKPGSSTALPSTTTTIDLGATDDQPQPKKSYVCLSPTLHGASSAASCCTPPYAGSSESSPELSTISPPSPPLFTLDNKAAEQEADSFFTNAGTTQDILFNSLQEGKSIPSWAKNRPLYTFKLHFKEDWGPRVTSLYEAAKTKSILDHTRVDEIALLSGIVHLNQKHIGFSQSEISKISGEVLNMFYSKEMEDADMRRAEYATIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SUT9</accession>
    <name>A0A9P6SUT9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Catalase</fullName>
            <ecNumber evidence="12">1.11.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BGZ80_005345</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 13">Catalyzes the degradation of hydrogen peroxide (H(2)O(2)) generated by peroxisomal oxidases to water and oxygen, thereby protecting cells from the toxic effects of hydrogen peroxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 12">
            <text>2 H2O2 = O2 + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:20309"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="EC" id="1.11.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 12">Belongs to the catalase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.6" evidence="12"/>
    <dbReference type="EMBL" id="JAAAID010002640">
        <property type="protein sequence ID" value="KAG0006142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SUT9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004096">
        <property type="term" value="F:catalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042542">
        <property type="term" value="P:response to hydrogen peroxide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08156">
        <property type="entry name" value="catalase_clade_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.180.10:FF:000001">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.180.10">
        <property type="entry name" value="Catalase core domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018028">
        <property type="entry name" value="Catalase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040333">
        <property type="entry name" value="Catalase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024708">
        <property type="entry name" value="Catalase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024711">
        <property type="entry name" value="Catalase_clade1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011614">
        <property type="entry name" value="Catalase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002226">
        <property type="entry name" value="Catalase_haem_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010582">
        <property type="entry name" value="Catalase_immune_responsive"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020835">
        <property type="entry name" value="Catalase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11465">
        <property type="entry name" value="CATALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11465:SF9">
        <property type="entry name" value="CATALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00199">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06628">
        <property type="entry name" value="Catalase-rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038928">
        <property type="entry name" value="Catalase_clade1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00067">
        <property type="entry name" value="CATALASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01060">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56634">
        <property type="entry name" value="Heme-dependent catalase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00437">
        <property type="entry name" value="CATALASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00438">
        <property type="entry name" value="CATALASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51402">
        <property type="entry name" value="CATALASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 11 12" id="KW-0349">Heme</keyword>
    <keyword evidence="7 12" id="KW-0376">Hydrogen peroxide</keyword>
    <keyword evidence="6 11 12" id="KW-0408">Iron</keyword>
    <keyword evidence="4 11 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 12" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Catalase core" evidence="15">
        <location>
            <begin position="1"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="339"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="360"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="29"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="102"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="11">
        <location>
            <position position="312"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="non-terminal residue" evidence="16">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR038928-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR038928-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM01060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0006142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="456" mass="52193" checksum="6BD7A5479BB7865D" modified="2023-09-13" version="1" fragment="single">MSSPPAMDFHLIDKLAHFDHERIPERVVHAKGAGAHGYFEVTEDLSHLTSAKFLQKPGIKTPIFARFSTVGGEKGTSDSLRDPRGFAVKFYTEEGNWDMVGNNTPVFFVRDPLKFPDFIHTQKRNPQTNLKDPDAYWDFLSLSQESLHQVTILFSNRGTPYSFRHMDGFSSHTFKLVNAEGVAHLVKWHFKTDQGVKNHTQEEAAELDSSNPDSNTEDLFDAIHKGEYPSWTVYLQIMKEVDAATYRWNVFDVTRVWPHSDYPLKKIGKMTLNRNPSNYFAEVEQAAFSPAHLVPGIDVSNDRMLQGRLFSYSDTHRHRLGPNYLQLPINQPYRAKVSNHQRDGPMTFSQNFGDQPNYEPQSQDPSGPQQQLEDIRAKVSSVKLDGATGRFPHRKSDDDFIQPGNLYRLLKGKEQDDLVKNIVSHIKKVKNPEIIRRQIGLFSKADPEWGRRVEES</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SVN6</accession>
    <name>A0A9P6SVN6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004877</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002440">
        <property type="protein sequence ID" value="KAG0007268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SVN6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="43"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0007268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="81" mass="8745" checksum="1D9397A7129E1FF7" modified="2023-09-13" version="1" fragment="single">MSQVKTQQRISLQALGAPRSPTTFVASPGRPRRININLPQHSATSAAFTSSSTGSSTLTQEAVHEERTRYTMLVAKNATSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SW03</accession>
    <name>A0A9P6SW03_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_004490</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002288">
        <property type="protein sequence ID" value="KAG0007575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SW03"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0007575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="254" mass="29508" checksum="31E72E4A80D9B56A" modified="2023-09-13" version="1">MLKARKLARETELHRLFPYTQKWDSPAMHQLHLELTGQLLRKTLVRRDYNRAFKLYSTLTATSKVCEDFVWKKVSILIETALYQLRFGKLEDAHTTLEPYINIYPYNENPLLLGYAGVVEFALWSKNIRMKYSNGLENNQDIDIDRVSGVNDKAGTHDDWMEDEEDESNDARQWNSRISRHGNAAANLLEQALEKDPKNDMFLTYLVRLRCGKVGMAGLGSKSISRKRKLAIHDMKGYLKRFYTNNNDSILSLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SW67</accession>
    <name>A0A9P6SW67_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_004241</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002184">
        <property type="protein sequence ID" value="KAG0007774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SW67"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050562">
        <property type="entry name" value="FAD_mOase_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356:SF2">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356">
        <property type="entry name" value="FAD-DEPENDENT MONOOXYGENASE ASQG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="11"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="419"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="707"/>
            <end position="786"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0007774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="842" mass="94122" checksum="337C6B874012BA87" modified="2023-09-13" version="1">MSNPMDTPIPTVLIVGAGLGGLMLGAILESANISYHILERATELRSLGSAIAMFGNILPAFEQLGIYEELKAVSLPHISSDFYDAKLNDLGSMSTKDHKIVCGYDILVTARPKLYDILRRKVPTHKISMRKKVLRAKEQDSKVTVYCSDNTIYECSILVGADGAYSAVRQSMYKELEKEGNLPLDDKEAFSIGYITMVGVSNPPSPEKYPQLIDNSRSYFRTVLGENSDSCYVVTAPDNQICWGIQIQIPENKAKEQHFRNSEWGPESVDATLEEFQDFPCAFGGTMKDIFDATSKNLISKVFLEEKVFQTWYHGRAVLIGDGAAMAMKDAVVLANCIHNMRDMSDKSIKTAFASYYRQRYLEADNLTKNSAIFTKIMFGHYRAVVRDMLFHKKEGRKDAERKRVQPRAMTEPTNDPSITVLIVGAGLGGLMLGAVLERTNISYHILERATELRPLGTAIGILGTILPIFEQLGIYEELKSISLPHVSMDFYDTQINQLGSMYTENHKTVSGYDVLVTARPKLYDLLLRQVPAHKISMRKKVLRASEEDNKVTVYCSDNSIYECSMLVGADGAYSAVRQNMYEKLEEEGNLPLRDKDGFSIGYITMVGVSNTPKPEKYPELIDNRTHFRVVVGEKSESCYVVSAPNNQLCWGFQLQLSEEKAREQCFRNSEWGPESVDAMLMEFQNFPCPFGGTMKDLFDATPKDLISKVFLEEKVFQTWYHGRSVLIGDACHKLLPGGGQGAVMAIKDAVVLANCIYNMKDGSDKSIKAAFASYHKQRYPEAENVSVQSAIITKVMFGHLKEAHNGFAIRPQINWLPLVENRGSGKVLPQEGREDAATRAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWV2</accession>
    <name>A0A9P6SWV2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Eukaryotic translation initiation factor 4E type 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">EIF4E2_1</name>
        <name evidence="2" type="ORF">BGZ80_003584</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic initiation factor 4E family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001959">
        <property type="protein sequence ID" value="KAG0008318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWV2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016281">
        <property type="term" value="C:eukaryotic translation initiation factor 4F complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000340">
        <property type="term" value="F:RNA 7-methylguanosine cap binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.760.10:FF:000043">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.760.10">
        <property type="entry name" value="RNA Cap, Translation Initiation Factor Eif4e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023398">
        <property type="entry name" value="TIF_eIF4e-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001040">
        <property type="entry name" value="TIF_eIF_4E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019770">
        <property type="entry name" value="TIF_eIF_4E_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11960:SF18">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4E HOMOLOGOUS PROTEIN, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11960">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01652">
        <property type="entry name" value="IF4E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55418">
        <property type="entry name" value="eIF4e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00813">
        <property type="entry name" value="IF4E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="1" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU004374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0008318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="168" mass="19245" checksum="C2FFF599641FDDCD" modified="2023-09-13" version="1">MHRAPGSKILSYESSMKKIATFGSVEDFWAVYSHLRRPHELPHVSDYHLFKQGVRPVWEDATNINGGKWIVRLKKGLASRYWENLVMAVVGDQFEVGSEICGVVLSIRGAEDILSIWNRSANEGRINLKIRDTLKRVLNLPADTIMEYKTHNDALKDNSSFRNTDVFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SX17</accession>
    <name>A0A9P6SX17_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_002554</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001634">
        <property type="protein sequence ID" value="KAG0009280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SX17"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0009280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="531" mass="60637" checksum="DDAF4768F5A4FAB1" modified="2023-09-13" version="1" fragment="single">ETKSPEGQKFPFSLRRLCLEGNIYDQGKYHLFSLLQNSPQLEELSLPKIDDRCARNVVDTLHQFCPGLRKISIDNEGYPGGSYIGLWGPAAAVLLLPDLLTRVRGGHKPDLLNLRQSNLREIRLSLWQDVDNIFYRAILGSHTIASSSPSRLQVLHIVDAALNSTALPTQILGRCPHMKDLYIDGGQESPWEGGSRVGVDLEALVEQDWVCTGMESLKLDIGIKPQNDDGYSTRLMEFADLLWRLYQKLCSLKSLRKLELVWIGLGKLHSTPVEILLSVMNNNGEDGQKGQRIKITGSDLECMGLGGWPTTSQLNEHHYRNIAYPIALKCHQALEKLDDAHVIGYYFGSFPDNTQNRAKYYKSWDGLKNPWYFCDGDDEWLDEPWYRNCKTYIRTGKCHQRIILTGMTSLEKALASELWWVCSKLEYLKLDIEVKSRHLGDHAESDVKDGNKHVRLLRRLHQKHQSLKSPQELELPWVDAIDELQQEYDEDSHSVMNVIEEKTGPDTEKSQMTVFTRSELEWMGLGCFPSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SX34</accession>
    <name>A0A9P6SX34_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_002697</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001676">
        <property type="protein sequence ID" value="KAG0009141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SX34"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040198754" evidence="1">
        <location>
            <begin position="27"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0009141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="205" mass="21267" checksum="E727515F9AA6DDE9" modified="2023-09-13" version="1">MLASKVFQSVILAVAAMAMLGSSTEAAPSNAKCIQCFAPPTCPPCDVGYKCEITPATCNDCGSGKCVKETEEKCIQCFAPPMCPPCDAGYECKITPATCNDCGSGECVKSASLKTKETKAAKCIKCFAPPMCPPCDAGYECKITPATCDDCGSGECVKSASLKTKDAKFIQCFAPPMCPPCDAGYKCEITPATCNDCGSGKCIKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SX97</accession>
    <name>A0A9P6SX97_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_002200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001536">
        <property type="protein sequence ID" value="KAG0009638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SX97"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052981">
        <property type="entry name" value="Ingression_C2_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47052">
        <property type="entry name" value="CONSERVED SERINE PROLINE-RICH PROTEIN (AFU_ORTHOLOGUE AFUA_2G01790)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47052:SF3">
        <property type="entry name" value="INGRESSION PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2" evidence="2">
        <location>
            <begin position="14"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="359"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="359"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="423"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="440"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="474"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="492"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="522"/>
            <end position="540"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0009638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="586" mass="63723" checksum="37036FC5EC99175B" modified="2023-09-13" version="1">MHKLFHGRHAHHINKPLPEPLVDPDEGKTPIGELVIVPIQGRDLPNRERFGKQDAFILFKLGNVTKRSTTDVRGGQRPRWNNDQISILMYESDAKDATSLYVSCLDEDHQKNELIADCVINLAKVLEKGEQDDWFELSFKGREAGALMLQLTYFSYDPTHPTSKVNRPYKAPGPSNGAPLRRPIFPNATDRPVSQPAVSHEPADNEHVYKPPVVTEPVQSPPPAPTATGYPSNNNGRISPSGYPQDNNGRISPSGYPQDNNGRISPAGGMGTPANGRISPSGQNQYGGPQVPINAAHPYPPVNNFGYPNAQAPYPPVGYPNNISGGYPPQQIPQNNNGGYPPQYNTMNGYPPQLNNNQFNNGYPPQNFNNNNNTINGYPPQLPFNNNVYPPINNGPGGLYPPVQQPLNRPVSPNGGGYPPAGYPYSASNLYPPGVGGGYPPQQQQQQQQQQQQQQQQQQQQQQKSRPVPPPPTSSESGLNTLESESEPSTLPGSFPGSFPSSPPRDSNNSNNNFSALAGHKQSYNAGQPTSSNVPRSTSPMVPGEYPQARTPSPQPPALPPRDGGNNNNFHSHAPQAIMSPAYGRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXI8</accession>
    <name>A0A9P6SXI8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DnaJ sub B member 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">DNAJB5</name>
        <name evidence="4" type="ORF">BGZ80_001782</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001413">
        <property type="protein sequence ID" value="KAG0010114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXI8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051787">
        <property type="term" value="F:misfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051948">
        <property type="entry name" value="Hsp70_co-chaperone_J-domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44360">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY B MEMBER 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44360:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY B MEMBER 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="3">
        <location>
            <begin position="4"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="69"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="73"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0010114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="101" mass="10609" checksum="FED3EAA560C3EE20" modified="2023-09-13" version="1" fragment="single">MGKDYYNILGVSKDADEDQIKKAYRKLALKYHPDKNSEPEAKKKFHDISEAYEVLSDKNKRAVFDQFGEEGLKGGAGGPGGPGGPGGAGGFPGGFSGFPGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SY26</accession>
    <name>A0A9P6SY26_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_000970</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001213">
        <property type="protein sequence ID" value="KAG0011077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SY26"/>
    <dbReference type="OrthoDB" id="200415at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051916">
        <property type="entry name" value="GPI-anchor_lipid_remodeler"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14859">
        <property type="entry name" value="CALCOFLUOR WHITE HYPERSENSITIVE PROTEIN PRECURSOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14859:SF1">
        <property type="entry name" value="PGAP2-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="2">
        <location>
            <begin position="173"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="536"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="14"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="94"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="118"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="539"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="577"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="596"/>
            <end position="613"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0011077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="911" mass="101651" checksum="888017869038E56F" modified="2023-09-13" version="1">MSPFNETQPPEPLPEALSSPSSSSAPLSSNNRTVPTPRPGELLIYDCRPPSSSPQALGSTASLLDRDTANPIAIAHHASSPPTPTPNTGEATFQSQSSPRSTTNSNSSINMQGSLATSPLSEDSGSRPSSSTPSAVLNSGAGSSSSSSAHTTMTTSLSHDSTDVLFDRPIRCLQWNIERNYKAQEILDTLTELNADILCIQEIDIGCRRSGYDRDHFLEICKSQGLYGGFVPEFCELEHPKRKDRDQGGGVHGNAIFSRWPINGFRVLDHVHHAYEWERDGLKLNEPRLGRRFTIVADIQTPSGPLLCYSAHLEVFTGIVGRISALSDVLADSALYADKYPYQILFGDLNTISHSIARLAKAISNDQYRVASLGSQESEWWDNNLWSWHVQDGEFNLALATGGWSWLRRLGLLGLGTGRGQQGDKDAQKSSNLWPADIKYTHWLRSLVEAGIDNIKQARQDQLLTDKFITVEHQENYSYQLTAAGSEHPVIAHGHLDSDEFESEKSYHEDGSVVLVGRPRSPSIITLESSLIDRNECMSSSSTWSSPSTTSTRRYRRHEDSDDESEFDHQRGSGLNRTSSTPSTPSPTLRLIPPTPKEDKRNSFSKSREEDRGIPLLYDGEYDDDEDGVHDIGDELRDSLLRQQFGFYDNDTLYRNDQHINDTVMTTETTSQRDFTSTTTTITSTTTTTFTTTASVTASSAITKEDIFKDPQPPFLLSSLKMMHPFFSTQRLWSGFTPLVLHQARNPGFYDPWSSCNDVTLHNPNFFGLLKAKLDYTLLMNLKCVGRHVGNHDYSASDHKWLLVEVEFEREFETKATLANAEATDVVEKEKKPRGDKFVMPSKEQQYLWWRERRQEWGQSVQPIASEVDRHRGKKSHHGHEQGSSLLAKSLLTATLTTVAVGGFWLWSRGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYG4</accession>
    <name>A0A9P6SYG4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_000663</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001140">
        <property type="protein sequence ID" value="KAG0011477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYG4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="82"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="204"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0011477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="258" mass="29935" checksum="3A4FB8196A2301EB" modified="2023-09-13" version="1" fragment="single">MADHGFPKDVKVNITEDDRNDAPPPFTENELTQPLLAAEKDQAPTDKVPAEPRSFCPFRNRFRRGGCNSERRAKCRNKARKIFRRLFAAIALFWVYLTFFSDNNYEDDWGFEPYDNDDLPREFTPTWRNPVSPFHRSFDAFDFNDVSSGKCTDDLVPWDGPSFIETNLRTIRLGFGRGHIESNVTVRSGDVEVPTILIRANVTKVDDEGDDDRDDDDDDYNDYNDYDDDEHPHGRKGLHLEIKESDEALDLKFWADRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZK8</accession>
    <name>A0A9P6SZK8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phosphodiesterase</fullName>
            <ecNumber evidence="5">3.1.4.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">PDE9A</name>
        <name evidence="8" type="ORF">BGZ80_010804</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="5">Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the cyclic nucleotide phosphodiesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.-" evidence="5"/>
    <dbReference type="EMBL" id="JAAAID010000794">
        <property type="protein sequence ID" value="KAG0013845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZK8"/>
    <dbReference type="OrthoDB" id="546632at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004114">
        <property type="term" value="F:3',5'-cyclic-nucleotide phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1300.10">
        <property type="entry name" value="3'5'-cyclic nucleotide phosphodiesterase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023088">
        <property type="entry name" value="PDEase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002073">
        <property type="entry name" value="PDEase_catalytic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036971">
        <property type="entry name" value="PDEase_catalytic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023174">
        <property type="entry name" value="PDEase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11347">
        <property type="entry name" value="CYCLIC NUCLEOTIDE PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00233">
        <property type="entry name" value="PDEase_I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00387">
        <property type="entry name" value="PDIESTERASE1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00126">
        <property type="entry name" value="PDEASE_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51845">
        <property type="entry name" value="PDEASE_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 4 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDEase" evidence="7">
        <location>
            <begin position="1"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="208"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="270"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="441"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="585"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="757"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="208"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="219"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="239"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="278"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="447"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="67"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="330"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0013845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="829" mass="91315" checksum="CFD1FDDC2AC15B6F" modified="2023-09-13" version="1">MLKFRSGKFKTMDAHFKIWEHTIPEIYGIILGMFVKLGLIDCLGITEGELLDFIIDVDRGYLATFYHSFYHAADVTAVLYHILLDMNASQYLSKPEMAALLLAGLCHDIGHPGLNNLFQINAKTELVKKYGEASVLETYSCSLAMDLVAKHRLFRNVSKSPAAILPEGNHATEESMKASMIKAIMATDMSFHYDMLNNLNTLIEFISTPSSTPSSSDNETTETESEMDFESSPPPSPTQPNGTHNNTIPDISPSLVEAVNNIRPRFECTITRSHHRQSSISSTSSESSDISIDSDGSTQTTRSVDIPRSPCDLTPELRQSFANCLLHAADISNAVKPWEICKHWSDLVVQEFFRQGDIEKSQNLPVSPNMDRAQHNQPQISLGFSDFVVQPYFETFVEFLPEAAPFLVSLTSNREQWALQKAAMEAAKESPLAVDATTIAETNAENQSSESPSEQPLTSGRRVSVAAGVVILDDTRPQRPALHRKLRHTTNMDNSQYHTVRKIKRSLSGRSLSTSLRDFQVNSPQPLLSTNLSPNKAVICTEAAASALRLEEALSGKNSAGPKFYIGAQEGSADQYLLPPMPLLQQRSDRQDDPPRLSYSDSDSAPYRQRRHGSLQLENRHPSIRQEYGNGYVILNHPDTALESSCSRPDQDINTKHIPLDPPHTFPTPGVWPTSLRSMDPEPPLENIAFFHQGHHPLDERNGHEKLSPHPSQNLVRLHQASSRCSTPAVLFGSIHYDWAHNADQYGLGPLDMSPDASVAGLSGGQDQKQASKDEKAPLSSNEETAGCIVGTPGLKSEEKEPWLTDSSISGVDGMVNISTAATGLSLTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZX2</accession>
    <name>A0A9P6SZX2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_010214</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000689">
        <property type="protein sequence ID" value="KAG0014805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZX2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00065">
        <property type="entry name" value="FYVE_like_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036361">
        <property type="entry name" value="SAP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68906">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="150"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0014805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="171" mass="19329" checksum="AD5883ADBE6EBA32" modified="2023-09-13" version="1" fragment="single">MVCDDCSKYKAKLEKFGWYRDVRCCGYCAHFLNVYKLDDAKLAKLQVRTLKRYLSAYNISTAGMIEKSELIKAVQERRPVPESSEIYFRENMPKTVEDWKLLLEELPSTSDITGSSEGLISDLDRFFSKIFGGDDAKSRKRIQSNAGAMPQSQQPSKPQAQPTPSHSSSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0B9</accession>
    <name>A0A9P6T0B9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_010012</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000653">
        <property type="protein sequence ID" value="KAG0015168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0B9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY MULTIDRUG TRANSPORTER MFSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718:SF9">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY MULTIDRUG TRANSPORTER MFSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01036">
        <property type="entry name" value="TCRTETB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="80"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="110"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="142"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="169"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="202"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="227"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="269"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="298"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="333"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="365"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="397"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="434"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="14"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="486"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="491"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0015168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="529" mass="56726" checksum="F8DAC03AA3D496E4" modified="2023-09-13" version="1">MLVVTPVKVPKWAILIVFCLAQFLDVANLAAVNITLPTIKAELHFTENQLPWIVNAFTLTFGTFLLIGGNLGDKYGHKRLFLVGVIWFSIWSLVCGLSRGVVLLCIARAMQGLGAASTIPNAMALIQFTFTEEVEKSKALSIFSSSGALGFGIGLVVGGVFTATIGWKYIFYISAIMGVAIAITAYFVIPESSAESRANVKLDYWGAITITAALLAFVYGVSDGHWASPQVIVCLILSVILLAVFVWIENKVEAPMLPMSIFRTRMFSAMLIVAALYQTWYLVYNLYCTLIFQEIMGYGAMNTAFAFFPLAFPGLILNPIAGHLIPKVGAKPLLVLGTGCMAVSAALFALANANTSYWPLPFPSMFLGEVGIAMTYTSAMVAALTMAKSGEHGLNSAVFQVAMQAGSGVGLAITNAISNAVIDATGSRLKGYQVGLWIGFAVTLLCVLITLVFVPSKSTLEKKKLAKAEAALRGLKDIEHASASNFESIEEEKGVDGSASERTECQEEASEKPQVKDRKGADLDPSLMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0I9</accession>
    <name>A0A9P6T0I9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_009748</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000610">
        <property type="protein sequence ID" value="KAG0015619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0I9"/>
    <dbReference type="OrthoDB" id="2448399at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0015619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="194" mass="22373" checksum="6194E36E5D643463" modified="2023-09-13" version="1">MTDDIEEHNDQLRFNTASDNQSSRDRLTNTAILVKKKLYKLLKSPYQAQSRTSPSKEDEDEEVKLNDPSRSVSSVYSVTSSLRAKMPLTPKTKTVLRQVKRRINTAARTVMSEASKAANDVTPILRSNTRKKSSTTYPRRFWPCTPQYEHGYDSENYYDPESIEDPGMDYQEQYHRYHSGYNNEGITGHPQNAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T155</accession>
    <name>A0A9P6T155_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">rhizopuspepsin</fullName>
            <ecNumber evidence="3">3.4.23.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BGZ80_008156</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of proteins with broad specificity similar to that of pepsin A, preferring hydrophobic residues at P1 and P1'. Clots milk and activates trypsinogen. Does not cleave 4-Gln-|-His-5, but does cleave 10-His-|-Leu-11 and 12-Val-|-Glu-13 in B chain of insulin.</text>
            <dbReference type="EC" id="3.4.23.21"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.23.21" evidence="3"/>
    <dbReference type="EMBL" id="JAAAID010000434">
        <property type="protein sequence ID" value="KAG0017568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T155"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.70.10:FF:000115">
        <property type="entry name" value="Lysosomal aspartic protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF51">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 10" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Peptidase A1" evidence="12">
        <location>
            <begin position="92"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="15"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="15"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="110"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="301"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="123"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0017568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="915" mass="100556" checksum="DC7FF9314E2DAB8A" modified="2023-09-13" version="1">MAFMAKLSTLNIHQNNTSSEPALSSTLTAPSSGPTNIPPTQEIKRQLTSSYNNDQEESSPISLLDRLHDEIIQKRAFVGVAPVRGNSLDTQWVAAMLIGTPTQEFSVVFDTGSSDLWVSSVNCQTSTCMSLRRFVPSRSKTFQQGNQEWSISYADNSQASGLTGTDDVTVAGIEITNQTFGLASVNTGSTATSGADGILGLGFDSNAEISDAKTVVSNMLDQGQIDQQIVSVWLNKAADQDASLSNGGEFIFGGMDPSLYTGPITYVPVTSSKDWQITIDQVFIGKKQLSLSSSASNAIVDTGSSYILFPDYLATAFHRAIPNSQFDSKLGWLIPCSLASSRTVGDLIFVLGGQKFSVPISDIVILKSAYNGYCLSAIDSWGELAGHGSQGLDSNKAVNTPTVNKQPPTPGHQTPHQVIIHTDTSISFLPYLYKSVTITDYIQYLPPCLEKPPSNEFELEQGDLQELLESGEEELAFISDERLPVSVPLTSLRAYGHLVESLTFQFLENLEFGPEMYTFEDSEPETYSGLKQAEVFIEILQNCSFYRLNTLEIRGLNPAAVIRPLYGQCGSSYMWQEYSLSLQQTSDRAVGQVIEAAAAAATASAETTLAAISGSGITMKERPRGIRRIVVSGSSCFGRHSLRTIVDTASLSTTLEELDVQCCGYFRSEEMHFALSKLPNLKVADFRCRDKSADLDPYSGLLPKKLTDEEEVKYGCNSSSSTRAANDTVPIIPPAQWACRDSLESLRIGVTNASMEEELKYGFDCYGYNSWICGAKIYWTKDHPETKKAYPERLHWFFDQIATLTQLKELCLVSAKPKGHRSRSLELSLKTGLTKWSTLTALECLDVEELEHGIGLEEVRWMVDNWPALRMIRGLVFENEDPSDAVFWLTKARPDISLPVSPLRAVKVSNEYEDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T162</accession>
    <name>A0A9P6T162_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Vacuolar transporter chaperone complex subunit 4</fullName>
            <ecNumber evidence="3">2.7.4.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Polyphosphate kinase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">SPX-dependent polyphosphate polymerase VTC subunit 4</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">Vacuolar membrane polyphosphate polymerase catalytic subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="primary">VTC4_4</name>
        <name evidence="18" type="ORF">BGZ80_008280</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>[phosphate](n) + ATP = [phosphate](n+1) + ADP</text>
            <dbReference type="Rhea" id="RHEA:19573"/>
            <dbReference type="Rhea" id="RHEA-COMP:9859"/>
            <dbReference type="Rhea" id="RHEA-COMP:14280"/>
            <dbReference type="ChEBI" id="CHEBI:16838"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.1"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:19574"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Vacuole membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the VTC4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.1" evidence="3"/>
    <dbReference type="EMBL" id="JAAAID010000444">
        <property type="protein sequence ID" value="KAG0017438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T162"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033254">
        <property type="term" value="C:vacuolar transporter chaperone complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008976">
        <property type="term" value="F:polyphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006799">
        <property type="term" value="P:polyphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07751">
        <property type="entry name" value="PolyPPase_VTC4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14480">
        <property type="entry name" value="SPX_VTC2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.100.30:FF:000001">
        <property type="entry name" value="Vacuolar transporter chaperone 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.100.30">
        <property type="entry name" value="VTC, catalytic tunnel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003807">
        <property type="entry name" value="DUF202"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051572">
        <property type="entry name" value="VTC_Complex_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018966">
        <property type="entry name" value="VTC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042267">
        <property type="entry name" value="VTC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46140">
        <property type="entry name" value="VACUOLAR TRANSPORTER CHAPERONE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46140:SF1">
        <property type="entry name" value="VACUOLAR TRANSPORTER CHAPERONE COMPLEX SUBUNIT 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02656">
        <property type="entry name" value="DUF202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09359">
        <property type="entry name" value="VTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="692"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="719"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="759"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="domain" description="SPX" evidence="17">
        <location>
            <begin position="1"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="554"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="627"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="561"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="630"/>
            <end position="644"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00050204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00061390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00067464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00075894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00080494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00081313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAG0017438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="830" mass="95618" checksum="56561EB2D8163A64" modified="2023-09-13" version="1">MKFGEHLAQSIQQEWSFNYISYDELKNVIKSRTSMQAWTETDEGYFVELLERELEKVYSFQSVKIGEVHRKLSFYNTQAQEFKKGGAQEETWRALEIELYRLVAEIDVLAKYTRLNYTGFLKIVKKHDKQTGWMLKSIFHVRLNTKPFHKESYDAVIVRLSSIYHVVSARGQKLKGDNQFSNWDSSAFVRDTTKYWVHPDNITEVKLVIMKHLPVLIFNTKKEYEENDSAISSVYVDNEEFECYQGRLEKTDMAQAIRIRWYGPTPTDNGQCFLERKVHREKWTGEQSVKERFPIKTKYINPYLAGDYTMDVKFAKLRARGQKSVKDVEVMQKLANDVQTSIVTKKMRPTIRAFYRRTAFQLHNDARVRISLDTELALIREDDFNGRKRAGDNWKREDIGIDWPFKQLPAEDITRFPYAVLEVKLQTHHGQEPPAWIIELINSHLVESCPRFSKYIHGVATLLEDKIQILPFWLPQMDQDIRKPPNTDFGLSAFLPRAWPVGTPQVGPRPTLVPRALIEGSSESTIKGAKSLSEFEPKKPKLMDKATYHQKMAEKNANRRPPNSETNFYNQPSGMASSKTSVSISHPLVDNGSTVSNQPLMAPPARPWIDRLNRDSMLSMGESFMTEKSQAANNNGNNPGQNNNDQGVLRKKSTIRRKHFGFREKRSATNPKRATAPIKIEPKIFFANERTFLNWLQFSVLLGSISLTLLNFGNYMTRVSGAVLTVITLLAMLYALGVFHVRLSNILSANPNRQFHDRIGPTVLCVFLFGAYFLNFYNLAIARASRLKIGITFRDINCSFKTNRIPRACLSGLRTSRQRVNDLRHDDPVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1G5</accession>
    <name>A0A9P6T1G5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Centromere/kinetochore protein zw10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ZW10</name>
        <name evidence="6" type="ORF">BGZ80_007616</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000393">
        <property type="protein sequence ID" value="KAG0018050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1G5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990423">
        <property type="term" value="C:RZZ complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007094">
        <property type="term" value="P:mitotic spindle assembly checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046362">
        <property type="entry name" value="Zw10/DSL1_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048343">
        <property type="entry name" value="ZW10_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055148">
        <property type="entry name" value="ZW10_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048344">
        <property type="entry name" value="Zw10_middle"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12205">
        <property type="entry name" value="CENTROMERE/KINETOCHORE PROTEIN ZW10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12205:SF0">
        <property type="entry name" value="CENTROMERE_KINETOCHORE PROTEIN ZW10 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20666">
        <property type="entry name" value="ZW10_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22766">
        <property type="entry name" value="ZW10_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20665">
        <property type="entry name" value="Zw10_middle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Centromere/kinetochore protein zw10 middle" evidence="3">
        <location>
            <begin position="259"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="domain" description="Centromere/kinetochore protein zw10 C-terminal" evidence="4">
        <location>
            <begin position="473"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="domain" description="ZW10 C-terminal helical" evidence="5">
        <location>
            <begin position="618"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="22"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="312"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="45"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="22"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF20666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF22766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0018050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="785" mass="88180" checksum="53131D8AB71E23BE" modified="2023-09-13" version="1">MATSVISSHVFARFVTSQLSESESTSPATLQSLQHGEGDNTPATSEDLTQALSSLDTEIQSIKAQVYKKLLANYNAFSESFEYSLELRDKIDELLLQADNMTSQTIHPETGLRQKVMSALVDHHEISYKVQENNAVLEGLNHFSRVEDILSQYEDYMDAGKILQAGHCIQQAVKTLAQPPNAGVAASKITKSLTEQCAMMTEAIDQMLDELVAGALHIEQPEDMDAHKFNLSLSYNIKVPPLSLPRSSSASTPGTIRWHELVRALTLLDVAKEKLRPLQKALTRQLLQPLIQLHQQVHLQLESSGNYATANGSSISMSTTEGQNTGGYSDSEFNADGSSSDTEILTYFIGRNIAKEACSMISKHYLSKVVPADVEGLSNFSSIATAATQFEDELIAIGFLTETDRVLRDFVETIDVHYTNRKRDTLLKTGRYVIMNDDFKTIQVRDLDRQDELEIEEDGWGRVVDMDTDLKESSISTKSKQIVEIVLKTLNEAGSLSEAAAPHLYQATRSLIDLYRALTPVHHARTLLNVPALTILFYNDCMYIARELGKVPARMEEGIPGMDEVQYDDVIPSLKELAKKWLDIQVQKQSEELMQSIDDAHEFRDSSLDSNYSAYERSMKQIVLVFRHLGKAWKPTLSPMTFYKVLGKLLDNVALRVIKELEGLKDISEKESHKLASLCGVLFECEDQFDSAGPLVEQIKGNSYNDEDPIHFFVPSWEKFQLLTDILELSFAEIMTRFRAGQLHMFRERELSNLICALFADTPLRQHNLHEIEQGHPLPLNRLRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2B2</accession>
    <name>A0A9P6T2B2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Rap1 GTPase-activating protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RAP1GAP2</name>
        <name evidence="4" type="ORF">BGZ80_006804</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000338">
        <property type="protein sequence ID" value="KAG0018740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051056">
        <property type="term" value="P:regulation of small GTPase mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1120.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11210">
        <property type="entry name" value="Rap/Ran-GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035974">
        <property type="entry name" value="Rap/Ran-GAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000331">
        <property type="entry name" value="Rap/Ran_GAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050989">
        <property type="entry name" value="Rap1_Ran_GAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15711">
        <property type="entry name" value="RAP GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15711:SF22">
        <property type="entry name" value="RAP-GAP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02145">
        <property type="entry name" value="Rap_GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111347">
        <property type="entry name" value="Rap/Ran-GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50085">
        <property type="entry name" value="RAPGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rap-GAP" evidence="3">
        <location>
            <begin position="1877"/>
            <end position="2096"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="40"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="77"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="355"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
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            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="525"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="566"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="602"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="670"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1059"/>
            <end position="1089"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1164"/>
            <end position="1189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1207"/>
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        <location>
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            <end position="1410"/>
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        <location>
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            <end position="1802"/>
        </location>
    </feature>
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        <location>
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        <location>
            <begin position="2242"/>
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    </feature>
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        <location>
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        <location>
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        <location>
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        <location>
            <begin position="3019"/>
            <end position="3102"/>
        </location>
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        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="40"/>
            <end position="55"/>
        </location>
    </feature>
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        <location>
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            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="89"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="134"/>
            <end position="148"/>
        </location>
    </feature>
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        <location>
            <begin position="160"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="186"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="214"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="247"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="258"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="273"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="301"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="364"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="489"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="525"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="576"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="632"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="642"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="672"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1065"/>
            <end position="1077"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1164"/>
            <end position="1182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1215"/>
            <end position="1228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1377"/>
            <end position="1388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="1712"/>
            <end position="1723"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1783"/>
            <end position="1796"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2120"/>
            <end position="2139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="2383"/>
            <end position="2402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="2489"/>
            <end position="2500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="2572"/>
            <end position="2582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="2757"/>
            <end position="2767"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2840"/>
            <end position="2866"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="2885"/>
            <end position="2901"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="3078"/>
            <end position="3090"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0018740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="3140" mass="336606" checksum="84E13492DBE00B4A" modified="2023-09-13" version="1">MNTFSTTQQDTPVDTNPTITPISPLTTITPLIPLTSTTQMSAIPPISTPSSPTATLEQCLPSTTEKPSTLATLVHNQTSSSQFCDSPESTSDSASINSSDSSDQNIIQPLPPTDVLDLEADNASPAQNTKSRPGSKSFGFFGSLSSKNSKQKMSKRNKESPSSTAILTADSTPPSSSAKLIFSEHGVNNVSNQSEASINGTNELKDGSQQPRPSETKRQKDKENNHPHLGLRISKAMGLTSSSPSKDQQRGIRESEENLSNTDGNSQPSTPDESSRQRESQNPDKDRKGGLVSQFLRHKVMSSSDGNLPRNQTPSSATRKVEERRPSFTPALKSTIQGNHFAIPAQLPSLPFFTTGGDVSSQSRSKEGDESRGIKGEKPWQEIPSRYGFGHGGGKLVMNPSLFNHRRGSLQIQIPQMHPQSVADIMESSREAHPHHNPDDLERQDLCSSLGLTVGERPIGSMNNHMYNILARRRGSLNPVSADIRVHTPSQSNNLSTSNSSIDSSKPPSRLARLTRFKFPSISVGSMNRNKSSTALGSDGSSQEPILNNIRRGSLPALKFSSQLESSKRKLPVIRSSGSDSTSASVNNTALAGMAPGSITYNGIHNNRHDPDVTNVGDGKKSRQSLSGFLEESSHHPHHDSTAISNTEQTSATPSFPHRQIAANHEKGIHNTLPQFHRSTSKNNFGSERFTSSTSGSHDREQGLPNVQGNGFGGGIRSSILKRTSRRTVSASHISSDSIFAVCEPETAEDPDSKNRTSRLSMGKQFRSEWNMQSAAAPQTDDDPNTILPAQKTNGDAGSVGQYLFGDELRNISFGEADTVASLTATPQLEGVPSSTGLLSSQSKAAAPLNAKKSSSSIKNSVETLVASVRPSFDSMIKDHTVATKSASTAPGDLPFGTNGKPLLSSVNVNARSERNGGLSQYTFPPMQPTASSASSTPVLKPKFSIIGSGNNHTTLSSLISGRNSSNHNNSFASATTTSVSNLATSTAANASTKLTTYHTPTPSQLRNPNVPHLEPRSAVADYTPIIHYKQQRSMSLQDADLLTADQFIALMPDDMPTKRRFSSEEASPENNWNTAPRTKKAPQPDPSSVLRSLLSTLQSKCGLIIKHLDAMSPPTSDFPVINPSVDTGIEEDVSVSMAADIVSDSNEVSAISEAPVPRTKVSISSPAILSNPPSHITTNHSESQKHVTETAIPADQMKAAEILHAGSTGSKGTGGDKDHGYPERNADSNDFDGQIEFSEDSLDIVTTLFDEMDHTVSQMTEVLAKYISTERFSKLSKELDEMCFLAQTVIRTEIDKRGIHNEEFEKFDDHYTFGESTFETPRIKREHIPTQRSLDFGTSATAGIATSSTAAAVVGTSSRPETSLEVDISEERQVRNKTSMDMASNRQDPGHCKHQYQQHPDSQKSEDSSNIDLKMTNEEQKLVVKNYVSSLLSAAESCVAEYMREYNRMFVVPTTGYRIEGCNDLVKIERALRPDHPHAPALPLSMTASEGASQPSLLSRASIVQNSIEPATQDSADNNKSPMGAQLDLVTYLHSTTSLSAINLSGQPMARVQSLPESNEWAELQKLKEMGESAGVAGAISMGTPVGAGNLGIISGPDISTLDYSQEHMGHEAYYYRNWFLGKEHRTYVGQVEGLGTVIISIIKDMVVPTESRPPLPGRSNTGPLISSSIASSSSMASILSSPAAHAAGSSSSARSELIQASHNLYPGRGTNLGGGGGGGGNLVASPRPSSEAMRVILSASTAVVAGSGNTLDYISLQSTVASALNGFPPAPTTHSSQALKSVSSSPVPVPTSTSHGNQSSATSRWQYRCILRQKDVDNLRITLPEPESGPLNNLTRRVGKPQWKTILTSIHPAITQQVASKLKKVETNPQFEKELAKFDETMLRFNYKFGVLLVLPGQAKEEDWFSNQMTSSPRFQEFLESGALGQKVTLKGFERFSAGLDTRSNSGAYSYFDTWGEGFEIMYHVSTLLPFNTGDRQQIQRKRHIGNDIVCIVFVDGDHPFVPNTIKSQFLHIFVVIHPIVLPDGTRGYSAAIACDDQVPPFGPPLPHPPIFRTPQELRAFLLSKMINGENAAYKAPRLIRPHQRARSGMLETLVAKANCLTKDKDSDKKSAKQKATAAAAVTTTAPPTSVTPSTSQLAGALPTGQPMAPGSHHATSTPIAAPISFHQGYTYQYIHGHDHHGYQDQQVNRGSYENYGMSDELQYHSHRANGKKVVSAPPGPRIGARASLVSLGSETAASIFRTRRRNSNSNESKPDAGVQTGGISKEKEGNETSETIGSGGSRVEGPGYIENLQSSSPSPLPSPFMTCAPTSSFGNEQPPFETPLNGDQDRDGCCSCCGCCCTVNYSSYIPSPPSSYAHYKFPPSRPTSASEADKTPKSGAPQSQNTSGNSTPWARSEASSPAEIQFAVNRNSFPNLERPHIRHSVGAVESLRAASSEKEDSAGILGMSIGNYKGRSKSEIDLLLKTTPEGSQATMPKGPIAKAISSSLPSSYQSHNHGQGPYEVQQHHAGSSGPIGIPQANTNSSSAIAAPAHSSMKGRAHYFLATLVRRRASSNDTSALGPTVHLGSKPSNLSSASPLGTWNSAAEHNVQAQSGNCSHHHHCHGCQLHHQKHHHHCVRSRIGSTPSPHLHHQESTNQEPNMEQPLRFKEGYSLKSKAPIHINTSIASSPNFQNPGYYQTPSTLSSTSSSSHYTCSPLTSASLRSSAGTNGAFNFASGMPPQLLRRFSSRDALKRTSLSTDRRGSIDILGLSRGTASPSMSWGSHRSAREESNDASVMDSKSDTSSVAIIPSSELAVTPIGPMDAAIRTDGVFSESPSAYTTPFMIPTNSSNFIEADSASGTTPASASASVSGLSSSFPGSKADYTNFNPGTSPRGPIPRHNNGSGDSASEPHVTSSAAMPTHPFAVSAADQNIEKHLPMECLTSCNSYQGMAIENDPECLQSATTFASIPSSTSANTTAAGDSAVTNGGSSANFYDEALMENPIASKVVKRAASVESFLRRDGLLSRITSLRSKGTGLQESVANARRPNSEILPSHSSRVDHHHQPNLDPLMLGDHGSSSKATPVPVKKDAVTDKQSLLTPQSQSLEAKDTETRATTLNSIQSRTETRLRRISESQNSYCSLEVEQLDVKFDVVID</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2I3</accession>
    <name>A0A9P6T2I3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Maltose acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">CAS91</name>
        <name evidence="6" type="ORF">BGZ80_004631</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000234">
        <property type="protein sequence ID" value="KAG0020193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2I3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016407">
        <property type="term" value="F:acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008374">
        <property type="term" value="F:O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03357">
        <property type="entry name" value="LbH_MAT_GAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.160.10.10:FF:000025">
        <property type="entry name" value="Hexapeptide-repeat containing-acetyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051159">
        <property type="entry name" value="Hexapeptide_acetyltransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024688">
        <property type="entry name" value="Mac_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23416:SF23">
        <property type="entry name" value="ACETYLTRANSFERASE C18B11.09C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23416">
        <property type="entry name" value="SIALIC ACID SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12464">
        <property type="entry name" value="Mac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01266">
        <property type="entry name" value="Mac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="Trimeric LpxA-like enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Maltose/galactoside acetyltransferase" evidence="5">
        <location>
            <begin position="53"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="249"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0020193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="270" mass="29935" checksum="7CF1A13ED563703F" modified="2023-09-13" version="1">MTFHSSDIVGSNEASKPEEKPSLENTSVEAYAEKLEKEYNFTSLYLELDHTQKQRMLDTKTYDASDPLLFKERLRARDIVRVYNKTTANTPEELFKRQALLHLLTRGQMGTGCYIEPPFNCDYGCNITLGKGVYMNFNCVILDCGYVEIGDNTFLAPNVQLFGATHPINPQIRSKGVELGMPIKIGNDVWIGGGSIICPGVTIGDGVTIGAGSVVTKNVPPYTIVGGNPAKILKVLDKEKCQEEFREYEEHRALDDWTPPPKGTLALPSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2U4</accession>
    <name>A0A9P6T2U4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Twinfilin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BGZ80_005257</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G-actin.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Interacts with G-actin; ADP-actin form.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cell cortex</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000260">
        <property type="protein sequence ID" value="KAG0019801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005884">
        <property type="term" value="C:actin filament"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003785">
        <property type="term" value="F:actin monomer binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030042">
        <property type="term" value="P:actin filament depolymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051016">
        <property type="term" value="P:barbed-end actin filament capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11284">
        <property type="entry name" value="ADF_Twf-C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11285">
        <property type="entry name" value="ADF_Twf-N_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.20.10:FF:000042">
        <property type="entry name" value="Actin depolymerizing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.20.10:FF:000007">
        <property type="entry name" value="Twinfilin-1 isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002108">
        <property type="entry name" value="ADF-H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028458">
        <property type="entry name" value="Twinfilin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13759">
        <property type="entry name" value="TWINFILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13759:SF1">
        <property type="entry name" value="TWINFILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00241">
        <property type="entry name" value="Cofilin_ADF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00102">
        <property type="entry name" value="ADF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55753">
        <property type="entry name" value="Actin depolymerizing proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51263">
        <property type="entry name" value="ADF_H"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ADF-H" evidence="12">
        <location>
            <begin position="1120"/>
            <end position="1252"/>
        </location>
    </feature>
    <feature type="domain" description="ADF-H" evidence="12">
        <location>
            <begin position="1368"/>
            <end position="1504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1315"/>
            <end position="1378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1505"/>
            <end position="1538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1358"/>
            <end position="1368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1507"/>
            <end position="1527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00056419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00069496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0019801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1538" mass="170408" checksum="74A675CBEA1C7574" modified="2023-09-13" version="1">MSLTDVSSQDANNVDVAAICQAFHPIEGDDSLTVLSVKVPPFVAPEKAEDFTKAKKKEAFFDICLDTSGSMSGSGLRCAKMAMRRLIDHLINNCGVPPSKITVYLYSHVCTVRRLGQPGDDQWINSISTNGGTSFACVFNEIINHTKAHIREVERDLQRDDVDIDTTLFFLTDGQDMDAKNLQTAKDNLGQLLQHTPRLESTVHTFGFTGDHDAKLLSWLTSVGTNSGCFQYIRESPGIEKSMSTTLELLGTSAMVAQRKIEILITNADDSAQDWIPIKLDGDDVTGSTVVRQKPFNGGFILWREYQGADSESSNAESAIRELPVKWLAEDSFQRILRMTTFIQHELLRLVEAINNIGNNAGTADQKRAKLLEIDAETEAYSKTLGTMAFASARIKTKLARESCMTACQRTRSLLQSFLAVKADAHKQGGSISNTSLATFNSLAYGQITEAKLKAKLDSRAGKNTALFADLDNKVTEVVAGLDLDALEAAESQDTLRELSCAFSTNNFIEALRDGDCLCMTLDVSRSPGAIADPSQLVIKSIFPTFLTSSMFTLALGHSLSQNSPEDVHGGFDRNIDASIAPGVAQESITAVLPLYINKEHWQVAKLRMKPILGYVVTLDATGYTYSQSITVPFLVLIKALESYPMTEFNQRQIKLILETCDAIYQNSRSLRENTKNMVEQFCASHQQRTVDVITNIYVFMGHVICALRAGDITPAEMSSLMPKFEVAAIEEQIRRDMSWKVSDSLMGNIMDWLNIDRNRDVLVPGRRYREQHDAYVRALEDGDGNGNSGKESVYRSIFDDAREQQGIKSASSSQSVSSVAAIVPSLSISATAPTVKPVFSVPEFDPLAWELSQASLDRLDSIQNVISPTVDKIRRLLAVIQAPLDSDLPEVLTSRLGGISPTGLSDEFFARYSPKIRLATLLQAYAHTKNSDRRSVQSLMTPFERELAAGQDSASDEALQYMKSLYHTKMSHMINEIVADVEEKYLDSKKDEAAAIFTSTSDLKVAAGVLLEAKSRGGAGGRLATTCATSRMRLPREKIQMLLAGKFKGVRLFADQSSKGEILRWNPCKKILYRMFSNYHDKFSLDEWRQFHPHRYDEYFACRYVIDGYLNELSKDDQNEALVSQKLADAWKQATSGNTVRAVKVSIINESLEDDGIFDIKGTFEQDFSTVYDNLAENQPAYFLVRFDGARSSEWIFLCYVPDVAPIRQKMIYAATRASLTKDLGDSHFKDSIYGTNKRDFSLDGYKKHVASMAAPKPLTDRERQLAEIHANEKLMVENMKGGAYRKSHAPGMSFPLTERAVAALKKLSTPTRKLVVSPASTPLPKSPAMSRQNTVDETKKATSSEANVDEDEWDDADTKAEKKEPEVTSAEPEAEEELVVSDIAERTINFVKLSIDAENERIDLASEARITAKELVANIDQESPRFTFFAYEHTHNGKAHDSLVFVYTCPSKSKIRERMLYSSCRAGVLQAAKDDARLDVEKKLETTDVSDLAEEFILEELHPKTQSSLGSSSGGTTSTGTRGFSKPARPGARRVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T366</accession>
    <name>A0A9P6T366_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein phosphatase 1L</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PPM1L_1</name>
        <name evidence="3" type="ORF">BGZ80_004108</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000213">
        <property type="protein sequence ID" value="KAG0020505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T366"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832:SF668">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="2">
        <location>
            <begin position="287"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="803"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="200"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="825"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="902"/>
            <end position="923"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0020505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="923" mass="101756" checksum="2811CAE31EC4251A" modified="2023-09-13" version="1">MQLPEPLAALPPSTKLPDLEDFNLRAVQLKNPLFVAICKVLIVYGNAWQSAMDLVDGIRHFNLASLGGRTPKGTIQGAISTGLALAAALRTFDPIEKQRMNSTTYYRMDTRALEPPSAETMESHATDLAKCSGQMDNNLTQTKAAAADARRKSAPTPSSKQKKRKQAVGWDSDSMSSGSSDDEMRKLPNGNSKSSKRARTGSPSSSSSRSKTPAKQELPNGLKKLPKGYVYDTEINQSALMGLSINPSQTGEGQQQALENDFPDRRSQYGVDLSREPSMFAVEQQTGYTYPRLRTSGRERLPKIDCEDGYAVVDLKHSEGYLGRLFCITDGHGGRACSSFVIATIPGAMQVILGKYKPSDLSLPSIQDIIKTQITEAIRLIDKEYLDYKKQQYLLFKAKKILQDPGSDGTTLIVNIFIDKWMICINVGDSRSILGSRDSAGRWNVDFHSEDHTPSLERLAQTIYANGGEFVTHDDKVIKFDPNIKNDKKHRQSLKEARIRVRDGASNLYGIPYRTRNGQCASINLGACIGDVLYKLDPVNPVLSCKPDITFIDITTIQHGYLLMASDGLWDYVLRGGKVQDQNATVCQFVGDKIDRGWNHQRIVCTLSDREGITGLYSDSIQEYDDFTAILVTINNQHLMEGPREEGVQQMQNDGNGLDQQVIDAEQKSDLQMQDDQCQWNEETSSSTQMSEIAQETVQEDVQEDAQQTAPEMTMAETVQETSMPETAQHTSTSEIVETATAEIVEGVTTVKVVEETTTIAEQEEVTMSEAVQETMTATSISEPVEETISEAEAVQEISMPENVQETVTQESKPEATVSEIAQEPTASEVVQDTSKSEEAQALLVPEQDPKQAHTQTNGDIIEQPIDRDERMEVDDDGTGDSTLSEIDIDDSGLEQQASQSEDIDVDLTDAELSEDIDVDSTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3D1</accession>
    <name>A0A9P6T3D1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Acyl-coenzyme A oxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">ACX5</name>
        <name evidence="19" type="ORF">BGZ80_001450</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2,3-saturated acyl-CoA + O2 = a (2E)-enoyl-CoA + H2O2</text>
            <dbReference type="Rhea" id="RHEA:38959"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:58856"/>
            <dbReference type="ChEBI" id="CHEBI:65111"/>
            <dbReference type="EC" id="1.3.3.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Lipid metabolism; peroxisomal fatty acid beta-oxidation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 12">Belongs to the acyl-CoA oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000133">
        <property type="protein sequence ID" value="KAG0021909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3D1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003997">
        <property type="term" value="F:acyl-CoA oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005504">
        <property type="term" value="F:fatty acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033540">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA oxidase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055088">
        <property type="term" value="P:lipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.10:FF:000005">
        <property type="entry name" value="Acyl-coenzyme A oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.10:FF:000007">
        <property type="entry name" value="Acyl-coenzyme A oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.110.10:FF:000003">
        <property type="entry name" value="Acyl-coenzyme A oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055060">
        <property type="entry name" value="ACOX_C_alpha1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029320">
        <property type="entry name" value="Acyl-CoA_ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012258">
        <property type="entry name" value="Acyl-CoA_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002655">
        <property type="entry name" value="Acyl-CoA_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10909">
        <property type="entry name" value="ELECTRON TRANSPORT OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10909:SF250">
        <property type="entry name" value="PEROXISOMAL ACYL-COENZYME A OXIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01756">
        <property type="entry name" value="ACOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22924">
        <property type="entry name" value="ACOX_C_alpha1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14749">
        <property type="entry name" value="Acyl-CoA_ox_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000168">
        <property type="entry name" value="Acyl-CoA_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12 14" id="KW-0274">FAD</keyword>
    <keyword evidence="8" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="6 12" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-coenzyme A oxidase N-terminal" evidence="17">
        <location>
            <begin position="22"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="16">
        <location>
            <begin position="112"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase C-alpha1" evidence="18">
        <location>
            <begin position="254"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase C-terminal" evidence="15">
        <location>
            <begin position="467"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="13">
        <location>
            <position position="407"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR000168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR000168-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR000168-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF01756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF14749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF22924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAG0021909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="650" mass="72435" checksum="088A4A8C9A85B74D" modified="2023-09-13" version="1">MAQTQACKDLAAARAKTTFPVIDLTRYIHGSDENIAKRRKIAALIANDPVFNKETRVGKSRVQDVNIGLAMSRRLYQLQEEHNLSKEDLLLCTDEQAKYWGPLAENHQIIGCYAQTELGHGSNLSQLETTATLNRDSDEWIIHSSTFTASKWWIGGLGAIATHALIQARLIIDGKDYGAHGFIVPIRSLKDHRPFPGVKVGDIGPKAYGGFSKIDNGFVRFDHHAIPRENMLMRFAKVTRDGQYVKPPHSKLSYGSMVLLRSQMVRGAALTLARAVTIATRYSTVRRQFNVPTSRRDTDNLNLETQVINYPMVQARLFPMVAQIYAILAAGKKMTSMYNGMLSELMQGDISSLAEVHAISSGLKSTCTTMAATGVEDCRKLMGGHGYSYFSGISHLWSSYVPSNTYEGDNFLLTQQSARYLLKQFKLAISEPEKVTPYSKFVINAVDQGAFQSERSSVQVATDWLKPEAQLAAFGHRAGRLVAELAVVVQEKDTVWSDFNIECWKLCHAHSQYVLARCSIEAVSQATAQGMSPSTVVVLKRLSDLFSLHTIQASLGDYLEDYYLSPKQCQTLRQQIKSLQESLADDVVGLVDAFDFSDYYLNSALGSSDGNAYQHLWDRAQREEINQTEVVDGYKEYIVPILTQHGTTKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3R3</accession>
    <name>A0A9P6T3R3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">40S ribosomal protein S27</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RPS27</name>
        <name evidence="6" type="ORF">BGZ80_011494</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the eukaryotic ribosomal protein eS27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000093">
        <property type="protein sequence ID" value="KAG0022682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3R3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.100:FF:000001">
        <property type="entry name" value="40S ribosomal protein S27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.100">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00371">
        <property type="entry name" value="Ribosomal_eS27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000592">
        <property type="entry name" value="Ribosomal_eS27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023407">
        <property type="entry name" value="Ribosomal_eS27_Zn-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11594">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01667">
        <property type="entry name" value="Ribosomal_S27e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01168">
        <property type="entry name" value="RIBOSOMAL_S27E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0022682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="107" mass="11481" checksum="F02B8849836AB2F7" modified="2023-09-13" version="1">MSLVAAGPRSSTAAVSGWTQAGFFILAVDLLNPSHAHEQKTHKLKRLVQSPNSYFMDVKCPGCVQITTVFSHAQTVVMCSSCANVLAQPTGGITRLTEGCSFRRKQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3R4</accession>
    <name>A0A9P6T3R4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 10">Mitogen-activated protein kinase</fullName>
            <ecNumber evidence="2 10">2.7.11.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">MPK1_1</name>
        <name evidence="12" type="ORF">BGZ80_002243</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.24"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="10">Activated by threonine and tyrosine phosphorylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.24" evidence="2 10"/>
    <dbReference type="EMBL" id="JAAAID010000155">
        <property type="protein sequence ID" value="KAG0021504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3R4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004707">
        <property type="term" value="F:MAP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000013">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000647">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003527">
        <property type="entry name" value="MAP_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050117">
        <property type="entry name" value="MAPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24055">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01351">
        <property type="entry name" value="MAPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 10 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="19"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0021504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="416" mass="46968" checksum="D40270454C90C715" modified="2023-09-13" version="1">MPTHSFPVLNQQFIVDTKYQFIREIGQGAYGVVCAAKNTQTGEDVAIKKVTKVFDKTILAKRALREVKLLRHFSGHENITSILDMDITNVMDFNEIYLVQELMEADLHQIIRSEQPLTDAHFQYFIYQICRGLKYIHSANVLHRDLKPGNLLVNADCELKICDFGLARGFSDDAESNVGFMTEYVATRWYRAPEIMLSFQSYTKASGKPLFKGRDYVDQLNQILQILGTPDEATLRRVGSERAQAYIRSLPKMPKIHFQQLYPRASPLAIDLLEKLLDFDPAARITVEQALAHPYLAAYHEEDDEPSHDQIFDFSFETTDRIDEMKRLIAQEVMSYKASKEQALGSQNAGLRRAASLSAADRNATTAAAKNTPQSCQQIQEEPAMAEEAPVANHLAAAMEVDEDLERELSGQAMQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T419</accession>
    <name>A0A9P6T419_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Programmed cell death protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">PDCD6</name>
        <name evidence="8" type="ORF">BGZ80_009594</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000059">
        <property type="protein sequence ID" value="KAG0023367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T419"/>
    <dbReference type="OrthoDB" id="186625at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048306">
        <property type="term" value="F:calcium-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd16180">
        <property type="entry name" value="EFh_PEF_Group_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000003">
        <property type="entry name" value="Calmodulin A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051426">
        <property type="entry name" value="Peflin/Sorcin_CaBP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46212:SF3">
        <property type="entry name" value="GH27120P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46212">
        <property type="entry name" value="PEFLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="137"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="175"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="205"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="63"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="26"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="63"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="128"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0023367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="306" mass="35291" checksum="74B634E31455AC59" modified="2023-09-13" version="1">MATQQYYNPHQHNQQFAPAQNGVYAQQYQQQQQQQPQQQPQQQYSHHRQHSTYIGTSTSQLNMAQTTPYTPHPSATMTPQHQQQPPYQQYNHYNTYQPGPPSEMEFQRQQYHQMQQQQQQQQQQLQQNGGRPSSTLPALNSLRDWFDAVDTDRSGGLSCEELQRALVNGDGWTPFNMETVRMMMNMFDRDGNGTISFNEFIGLWNYIEKWKTCFQAYDLDGSGTIDASELQKALRGFGYNLSEATVALIMTKYDVRGRGDISFDNFVQSCVTVQTLTDSFRRIDVTGTGIVTMTYEQFLGLVISNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T4F7</accession>
    <name>A0A9P6T4F7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 19">Pre-mRNA-processing factor 19</fullName>
            <ecNumber evidence="5 19">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="primary">PRPF19</name>
        <name evidence="22" type="ORF">BGZ80_007281</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="19">Ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 19">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 19">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subunit">
        <text evidence="19">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 19">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 19">Belongs to the WD repeat PRP19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="5 19"/>
    <dbReference type="EMBL" id="JAAAID010000037">
        <property type="protein sequence ID" value="KAG0023919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T4F7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071006">
        <property type="term" value="C:U2-type catalytic step 1 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031124">
        <property type="term" value="P:mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070534">
        <property type="term" value="P:protein K63-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16656">
        <property type="entry name" value="RING-Ubox_PRP19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12398">
        <property type="entry name" value="RRM_CSTF2_RNA15_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000027">
        <property type="entry name" value="Pre-mRNA-processing factor 19, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.70">
        <property type="entry name" value="Transcription termination and cleavage factor, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025742">
        <property type="entry name" value="CSTF2_hinge"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026896">
        <property type="entry name" value="CSTF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038192">
        <property type="entry name" value="CSTF_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038959">
        <property type="entry name" value="Prp19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013915">
        <property type="entry name" value="Prp19_cc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055340">
        <property type="entry name" value="RING-Ubox_PRP19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003613">
        <property type="entry name" value="Ubox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43995">
        <property type="entry name" value="PRE-MRNA-PROCESSING FACTOR 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43995:SF1">
        <property type="entry name" value="PRE-MRNA-PROCESSING FACTOR 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14327">
        <property type="entry name" value="CSTF2_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14304">
        <property type="entry name" value="CSTF_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08606">
        <property type="entry name" value="Prp19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24814">
        <property type="entry name" value="WD40_Prp19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00504">
        <property type="entry name" value="Ubox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 19" id="KW-0227">DNA damage</keyword>
    <keyword evidence="15 19" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8 19" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="14 19" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="16 19" id="KW-0539">Nucleus</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0677">Repeat</keyword>
    <keyword evidence="17" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="10 19" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="9 19" id="KW-0808">Transferase</keyword>
    <keyword evidence="13 19" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="7 18" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="RRM" evidence="21">
        <location>
            <begin position="5"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="18">
        <location>
            <begin position="652"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="18">
        <location>
            <begin position="756"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="18">
        <location>
            <begin position="790"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="18">
        <location>
            <begin position="873"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="82"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="246"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="129"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="20">
        <location>
            <begin position="163"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="20">
        <location>
            <begin position="248"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00015618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="RuleBase" id="RU367101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAG0023919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="908" mass="97554" checksum="77E45EEA7BBD4186" modified="2023-09-13" version="1">MSGSKVVFVGNIPYEQTEEQLIEIFSEVGPVVSFRLVFERETGKPRGYGFCEFQDERTAASAVRNLNGREIGNRSLKVDYAETDPARNGGRDLEEGSFMRNIGPGSGPTGPPPSMPLLQQQQQPPPFMPLQGGPPRLDPRIANNPNVAPPPVNRPSMQQPPMGGAPPLAPPMAPGPSSADAISAVLATMTPQNVFDLISSMKVLGASEPDRAKAVLKENPQLSYALFQALLMMNLVEPSSLQRMFPAMPGPKAPAPNVPAPQQHLPPPQQHLPPPQQHLPPPPPQHMGIPPPHMQPPPHQFAPPAFPTMPPAAQPPVPQQSAPLAPSLEQQKALVAQVLALTPADIASLPEEQRANIIQLRAQLMGANVGKATNVENMSDCSAKKGAVVIFSVTKNIILSPHPPSALSRNMFCAISGEAPEQPVVSKKSGQVYERRLIVKYIEDNGKDPVSGEELSVEDLLDIKTSPGTVKPRPPTMTSIPSILSVLQNEWDSIMLETFTLKQQYQQVRQELSHALYQHDAACRVIARLMKERDAAREALANVQAHLGTKAPAAESSDVAMEDASGLSAEVLAKLDATMTALSKTRKRKPNVTAEAVQTYNQRKVFPGLHAARSPGITSLDLDAKNGLILTGGNDKNALIFSQSEEKVLATLKGHSKKITHVSWTGRSEVAGKDLALTASADHTVKIWSASGDNSYNYSAAHTLSGHTADVTGLCTHPCKDYVATASMDSSWAFHDLETGATLLTARSDDVTKGYTSAAFHPDGLLFGTGTADSTVKIWDVRTKEAAASFDGHTGAVKTMTFSENGYLMAAAGENNEVSIWNLRTMEVVQKLKVADQGVINTLAWDQSGTYLGVGGTDIRIFKVKTWQELANLTDNTAEITSLKFGPLGDYLVAGGLDRSIRVFGINE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T4T4</accession>
    <name>A0A9P6T4T4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008897</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000005">
        <property type="protein sequence ID" value="KAG0024739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T4T4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="180"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0024739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="195" mass="21477" checksum="4A3F7C3477D08F8F" modified="2023-09-13" version="1">MPIKPCIAKGQRECVGGFHRDQCFKCTKGSITCNMCNPDSSVPSPCIYCFNGRRECSDCFGLGHVQRICRPCIEDHYRRQSRKNTVTRVKSQLALAQNQFSRSMVSITNVIAPTSPKQGPSLHKSNHHSDTDVSKISISISSKLEKFSSKLAGKGLDTSVYDSTDSTESIGDKTHRRKWSWSSSPSNAPSSMVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ME07</accession>
    <name>A0A9P6ME07_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Arm-like repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007862</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004104">
        <property type="protein sequence ID" value="KAF9994302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ME07"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056251">
        <property type="entry name" value="Arm_rpt_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23948">
        <property type="entry name" value="ARM_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arm-like repeat" evidence="1">
        <location>
            <begin position="11"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF23948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9994302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="397" mass="44210" checksum="DC9F94B98DC3878B" modified="2023-09-13" version="1" fragment="single">ELDQSENDWLQAISNNSDEQERLRTIATDITRAFVRDELKTSDVVAETLSLAAVLKQDESRKLLEAFVDGIDQSLLLKVNLLDGLSRLMKNIPLGNLDSDDLVKILELLSSRLKNTHQQSTEHTYQLATAVSRVLDSMVDSQVEGIEREQLHEPLSQYLKDLQQSSDPCLVYQAAYAYQALQYIPDDETILQTMLRRTGKVVKGISGVVSAVKALDLNGFIDGLHHIQVGLNGASEAISMVSDAYQNAKTLIENGQGLLQSLQESFSFTRKSAWYPALRGLDALLQEGKVAEFEKLTREAPCRQDPAFQWGVCQRLGELAANTLWDVDIRQCAISFLGEMYSNDTIWGQHGSVKQLVLQTLSKLTESSEGTVASHAKRLLQNLETDGDSKKCDFYQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MF52</accession>
    <name>A0A9P6MF52_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Redoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_007320</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peroxiredoxin family. Prx5 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003721">
        <property type="protein sequence ID" value="KAF9996199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MF52"/>
    <dbReference type="OrthoDB" id="195498at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008379">
        <property type="term" value="F:thioredoxin peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037944">
        <property type="entry name" value="PRX5-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013740">
        <property type="entry name" value="Redoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10430">
        <property type="entry name" value="PEROXIREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10430:SF16">
        <property type="entry name" value="PEROXIREDOXIN-5, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08534">
        <property type="entry name" value="Redoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="5" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Redoxin" evidence="6">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9996199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="79" mass="8169" checksum="6D77C83F54F88F31" modified="2023-09-13" version="1">MDAWGKWTNTNDKIILAADGNGEFVTATGLVQDLTKIGFGAIRSKRFALVADDLKVTYVGVETGPGVSVSGADAVLAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MFX2</accession>
    <name>A0A9P6MFX2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 10">Peroxisomal membrane protein PEX14</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 10">Peroxin-14</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">PEX14_2</name>
        <name evidence="14" type="ORF">BGZ80_007119</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the PEX13-PEX14 docking complex, a translocon channel that specifically mediates the import of peroxisomal cargo proteins bound to PEX5 receptor. The PEX13-PEX14 docking complex forms a large import pore which can be opened to a diameter of about 9 nm. Mechanistically, PEX5 receptor along with cargo proteins associates with the PEX14 subunit of the PEX13-PEX14 docking complex in the cytosol, leading to the insertion of the receptor into the organelle membrane with the concomitant translocation of the cargo into the peroxisome matrix.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9 10">Peroxisome membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the peroxin-14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003596">
        <property type="protein sequence ID" value="KAF9996928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MFX2"/>
    <dbReference type="OrthoDB" id="5549158at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990429">
        <property type="term" value="C:peroxisomal importomer complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005102">
        <property type="term" value="F:signaling receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016560">
        <property type="term" value="P:protein import into peroxisome matrix, docking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025655">
        <property type="entry name" value="PEX14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006785">
        <property type="entry name" value="Pex14_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23058">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23058:SF0">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04695">
        <property type="entry name" value="Pex14_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 10" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="3 10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0811">Translocation</keyword>
    <keyword evidence="2 10" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Peroxisome membrane anchor protein Pex14p N-terminal" evidence="13">
        <location>
            <begin position="5"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="245"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="313"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="134"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="187"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="249"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00046271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU367032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9996928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="340" mass="36145" checksum="742C7CDC63B97D5B" modified="2023-09-13" version="1">MSGMREDILASAVKFLQDPKVQASPLGKKVAFLESKGLTSQEIEEAMARANGTSTGAATTVAAAGTTPGTVQQMAVPYQGQGQVVMAPSPPPPLPAKYDWKDMFIAAVVAGGFSYGMWQIAKRVIGPKLQWPSQEDLELDKKKLDEQFEEIEKSLAEVKTSTTVVAKSVDDQTSHVKESLESMSGVLEGMKNNNDKREQELVGLKTDIENIKDMIPKLIEKNKESQANTLNDLQSEIKSLKSLLMSRRPGPTGPSTPGGSTPTTPWASVPAGYGSLQNNTSISSASASTATPTPASSDLAMNFLNTRTSIPSWQLATNQSAAPAKADSTLEEGSETANNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MGL5</accession>
    <name>A0A9P6MGL5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ubiquitin-like protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">UBL3</name>
        <name evidence="3" type="ORF">BGZ80_006614</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003274">
        <property type="protein sequence ID" value="KAF9999210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MGL5"/>
    <dbReference type="OrthoDB" id="1043111at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040015">
        <property type="entry name" value="UBL3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039540">
        <property type="entry name" value="UBL3-like_ubiquitin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13169:SF0">
        <property type="entry name" value="UBIQUITIN-LIKE PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13169">
        <property type="entry name" value="UBIQUITIN-LIKE PROTEIN 3 HCG-1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13881">
        <property type="entry name" value="Rad60-SLD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="2">
        <location>
            <begin position="23"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9999210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="128" mass="13831" checksum="9ED4D85BA3484D1D" modified="2023-09-13" version="1">MSDSPTSANSPTAPGSSVDPNTVALTLLLVSGSRATFEFNGTETIQAVKNKVYENWPKEWQEEKPASPQSLKILYLGKFLADVSSLESNKIQPGTTTIVHLTIKAPEQEIHGHSKSDSAAKCKFCLIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MGZ8</accession>
    <name>A0A9P6MGZ8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Beta-lactamase/transpeptidase-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_006428</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003175">
        <property type="protein sequence ID" value="KAG0000085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MGZ8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.600">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050491">
        <property type="entry name" value="AmpC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021860">
        <property type="entry name" value="Peptidase_S12_Pab87-rel_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46825:SF15">
        <property type="entry name" value="BETA-LACTAMASE-RELATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46825">
        <property type="entry name" value="D-ALANYL-D-ALANINE-CARBOXYPEPTIDASE/ENDOPEPTIDASE AMPH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11954">
        <property type="entry name" value="DUF3471"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040294144" description="Beta-lactamase/transpeptidase-like protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase-related" evidence="3">
        <location>
            <begin position="45"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S12 Pab87-related C-terminal" evidence="4">
        <location>
            <begin position="404"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF11954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0000085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="505" mass="56160" checksum="210D52FEEA594EFF" modified="2023-09-13" version="1">MKIIPTSILILQSIALIHGAQRVFSGEGPRQYNAATPHADLHQILEDARVKTGIPGMSVAVLHRGKLVFAEGFGKRNELDPFTAETLMPIASVTKAFTAAAIGELVGEGKVDWDTTPVSKYLPEFELADPVFTSQLTFQDLLSHRTGFPPVDSAWTGETVPRKELIKRLKYIKTGSKLRSYVIYNNVMYGVAGEAAANVAGIPYEDLVLEKVLKPLGLNNSGFSTKEMSEHFNYAMPYQADSLEDAQNGKFKQAPLDDYTRVDAPAGDMYSNVLDLVRWGRAIMKYGEVDGKQILNRDSVTEMLSGQSIYKRERQSPEFGPISGYAGHVPGFTSNLALFPDSDLVVAHLSNIFTGSLTSFSAYLIADELLGLTKTLDWISVAIKTSQDYFDLVDESTRGNFPKRIENKPPTHDLAGFVGDYQSPSHSDISVHLKTNSEDKEELYIRFRDYDSKLDHYHYDSFSTTWEVSLFRIAQLVTFTTGEDGNIAGIQTEMDDSMIVFKRKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MHL8</accession>
    <name>A0A9P6MHL8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_006321</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010003112">
        <property type="protein sequence ID" value="KAG0000689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MHL8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004673">
        <property type="term" value="F:protein histidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.20:FF:000099">
        <property type="entry name" value="Sensory box sensor histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052162">
        <property type="entry name" value="Sensor_kinase/Photoreceptor"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43304:SF1">
        <property type="entry name" value="PAC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43304">
        <property type="entry name" value="PHYTOCHROME-LIKE PROTEIN CPH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAC" evidence="7">
        <location>
            <begin position="765"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="147"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="245"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="434"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="516"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="631"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="96"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="120"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="249"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="294"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="322"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="362"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="445"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="555"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="643"/>
            <end position="662"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0000689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="875" mass="97831" checksum="8A8B18E9250E3DE2" modified="2023-09-13" version="1">MDSSSSRYDSEGSYFPPVESAKDRLHGNSTAYSKTGYADFVQGLNPTWSQSPTPSPNIIKEDPTINPFFFQPLTSYPAMDDDAFDPPDPTPESTEDDHSFSSEQFKETRNHVRSPPRPRPSTSTSQTPPSLPTSAFANSRSLIHLPLYRSTDHNNQRYMPSDVRSNRPPAMPIGIISLLSDQVPYPPEALDVLTELNPFLANQVTNALRLEEMVTRSSRWGDISSLSERSRVNEPFTESVLRKMKESNNDTATPRPNQTLNQTQDYRYSTSSDKQYTRSKQSSKRRSADPIAEKSSNNSDQKTPASQQSSKKPGRTKKTFGSDFSTSRAPQQVSSEGGNRSTNPSQNQRDPTKPPKSRAAESGTSATSERKQNTFNFLSPDLERLDQDASSLRGKQPETCFNLDSTTDEIHRRLNMLNLDVTGSATCPLAPQTKKMLGRHHSPRSSHSTDGSLSSSWSHDRRRTESSPSLADIEKLEDVDAMWQTLQMEGISSRTRSLPNTLIENEFDIPSSESPFLGSMHSISPSSVPKRHLFSTSKRSGVRRRRKSFKDQAKNHQSQLHPSDSPVPNSPYTPTTPGFPSLRPEILSGNSSFGAPALSSDPSPIASPAVHQSGVFNQEFPVIGLGLSHNRTESGNDRMPLSRQGSGYSLNSDDTSLASPSLQHEKHYAGRKNKKKNAAFSERTGVNPFPRTRLLRLIVDSIAHHVFTLSPQSGCLTWLNQRSLQYTGTPLTQLLHSPWTRILHDDDKATFQPLFKDCFDRGEMFNAQYRVRRFDGQYRWFLGRILPVRDCGGNIVHWFGTSTDIHDQKLAELQLNRQVELELNEKKYRLLAEAIPQIVFTATPQSGLTYANAKWFTYSGQVFEQASGLGFLDHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MHQ4</accession>
    <name>A0A9P6MHQ4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003204">
        <property type="protein sequence ID" value="KAF9999830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MHQ4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="321"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="211"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="321"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9999830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="371" mass="40452" checksum="99B0D97F95EFA0A7" modified="2023-09-13" version="1">MATAPSFVTAPATAAPHSEYPSMTSSITYNPPYPATPLAYPTMPVHSLASPYPLSYPNTQVLQPEQHQPSAPFALIEDPVPSPPTTHQSTFEEAVTLQDSEDIQHKEQDLINLNDWPSPGATTAVLTPPSSTTSTMAAPAIELVTSYRCKKCGAILESETAACKRLHTPATILTERQIRNAINIDQDERTRNQIELVSPSSSSATLGRQRSNSGSTGSSNSLRVDRYENNHGTNDIYLRRRSHGHELTTAVQTIPSIENNYGTNSTYIRRSISVQTPVTALKKFWRDAKKEVNYKITQSQQRSVQPEIVAPPPLPYPIYQDTTSLNRSNTYAGSSTPAYNPSHAPSISSVYNPSHAPNGSPAYPVPDARLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MIK2</accession>
    <name>A0A9P6MIK2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cytochrome p450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_006056</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002994">
        <property type="protein sequence ID" value="KAG0001911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MIK2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF166">
        <property type="entry name" value="CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0001911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="334" mass="37393" checksum="425E357298F33AF5" modified="2023-09-13" version="1" fragment="single">MPLASTLIGTASVNPMTTLGTAVTLLSSYIFYIAYIYPIYISPLRHIPGPPNKSKNNKYNIPFLGLFLDLLKEDAGVPQLKWVEKYGGIISYVGLFNSRRVFVADPKAIQHVFNTNSYNYIKNPRTVHLLSQIIGLGVLLVDGDVHKKQRKMLNPAFSVKHIKEMAPLMCIPAELMANIWLERVDQSEGKSIEFDITTDLGRATLDIIGLAGFGYNFNALTEPNNELSTAYRKILYTGSRLTQLMRLYVPYYTSLPTSDNNRRWEAIATIDRVSTRLIAEKRAQALTKDPTFGPDGELIESRDLMSILIKGNESVGSLEDGKLTDTELKDQILT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MIP4</accession>
    <name>A0A9P6MIP4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Crinkler effector protein N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_005972</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Host cell</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002943">
        <property type="protein sequence ID" value="KAG0002468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MIP4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043657">
        <property type="term" value="C:host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045379">
        <property type="entry name" value="Crinkler_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20147">
        <property type="entry name" value="Crinkler"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Crinkler effector protein N-terminal" evidence="5">
        <location>
            <begin position="6"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="108"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="121"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF20147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0002468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="241" mass="26419" checksum="FF035E6D766A0D97" modified="2023-09-13" version="1">MTDNKLTLFCLVDGESTFNAFLVEIESTKTIGDLKKLIKTEKTPRFDDLLMSLLFGQSRMTTKKIPTLLDDLNGKKKLGPATRISKVFPGELPEETIHVIVQRPPPQVHAPVPARSLTPVPGQQSDGSRPSSPLSGDLQEDIKRIRDKFFAAGSKHAGFLVSYVQGQGSLPITETGLRGLPKVLRRGAVESEEAKPSLLFLDLPDPPSNTGDPVPERFKTNILLGVLEKMQAQDLPIFGVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MJ33</accession>
    <name>A0A9P6MJ33_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_005650</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002782">
        <property type="protein sequence ID" value="KAG0004243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MJ33"/>
    <dbReference type="OrthoDB" id="2347164at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="115"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0004243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="734" mass="83614" checksum="FAACA9509B251BD4" modified="2023-09-13" version="1">MSNTQKIESGEYSSWSEPEEGFYDEDRDQDYTDGYDDDDDGYYDDEDDVYYYYDNKGNMCSDVYGDFSVRAKAPPAHTRSRPFPAQKPMSKSSKPRSTNSTSPSDQLPRHDDNSVTTTLTLPPEVLHLIFSYLDNATLCHGISYASHQFNAIAKHYIECLWTLGTQRDEDILLEKLRLGKVNVLRIRYSTSPPEDSGRSQPFDKWDQAWKRFRDIVTQPINITEGATDGALHEQSVVDRLSVATETMAISAEKDQAPCLLWGVRKLIMDGGDLWTPGFLPTLLPFTRSIHKLVLNPWGWSQTRRIQSQWPLIYEIPLHSVLNACPSIRTLVIHGAASLCLNKEAPATSTQGTGHTFQLSRFILRNVTATQETLGNFLSSCPQLVSFKAKNIHIRTQGTPHHHLLNTPSLAVEPLLQRAAFLCPNLVDLSVIPDASAPINTFEHLLAKFAQYFPQTKHLVVQTPLCLDSSWVPTPTVAKFLAQVTSLGFSDSATTHSAQNLDRLLRHTHALERLCSACLPYSRKRKTEYPKQQYISLKTSWRCLHLREIELSVPDVARQEGVFRYLRYACPNVEHLTLYLFELRIGQAEPAVQVTYETYKHRALGRNWCGRLPLHRLWRERGIYTARREVCTEYWTKKDSTLWALGGLLRLETLVLRCQNVKGVLCPKDFKFMQIRRGGRGGSGDERAFCPRLKELQVISTPVPRCGLTKEEPLENRTVFMTILKSMRPGVDFRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MJP2</accession>
    <name>A0A9P6MJP2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">assimilatory sulfite reductase (NADPH)</fullName>
            <ecNumber evidence="4">1.8.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BGZ80_005553</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">This enzyme catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>hydrogen sulfide + 3 NADP(+) + 3 H2O = sulfite + 3 NADPH + 4 H(+)</text>
            <dbReference type="Rhea" id="RHEA:13801"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17359"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.8.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Sulfur metabolism; hydrogen sulfide biosynthesis; hydrogen sulfide from sulfite (NADPH route): step 1/1.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.2" evidence="4"/>
    <dbReference type="EMBL" id="JAAAID010002736">
        <property type="protein sequence ID" value="KAG0004791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MJP2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004783">
        <property type="term" value="F:sulfite reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06207">
        <property type="entry name" value="CyPoR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.80:FF:000033">
        <property type="entry name" value="Sulfite reductase (NADPH) flavoprotein alpha-component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.990.10:FF:000010">
        <property type="entry name" value="Sulfite reductase [NADPH] flavoprotein component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.990.10">
        <property type="entry name" value="NADPH-cytochrome p450 Reductase, Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003097">
        <property type="entry name" value="CysJ-like_FAD-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023173">
        <property type="entry name" value="NADPH_Cyt_P450_Rdtase_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384">
        <property type="entry name" value="NITRIC OXIDE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384:SF109">
        <property type="entry name" value="SULFITE REDUCTASE [NADPH] FLAVOPROTEIN COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00667">
        <property type="entry name" value="FAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0274">FAD</keyword>
    <keyword evidence="6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0288">FMN</keyword>
    <keyword evidence="9" id="KW-0521">NADP</keyword>
    <keyword evidence="11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="14">
        <location>
            <begin position="114"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00052219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00059320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0004791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="507" mass="57118" checksum="411778116812B67A" modified="2023-09-13" version="1" fragment="single">RHYETSNRKVLQDLISTLVERVDKEVIEVPQNPNWLTIELGEADKEALALPKHVQPTVRDTPSAFGGSLTTADEDTEISESEAVLGKTSNWHRAAWQLLFSEAYDTKQALADEGHEYLVTITENRRLTPTTYDRNVFHLEFDTSETGLKYEISDALGIHGWNDTQEVLDFIEFYGEKPETIVVVPRALPKNAPEGTLARSQTNSLFQILQQTLDLFGRPSKRFYADLIPYAANAAEKERLSYLISSEGAAEFKDRVDETLTHADILREFPSAHPSIPQLINMLPPIKPRHYSVASSQKAHPNSVHLLIVAVEWVTPSGKTRFGQCTRYLTSLGAGSKVTVSIKPSVMTLPPSPHQPVIMAGLGTGMAPFRAFIQERAWQRAQGMEVGPMVLYFGSRNRSNEYLYGEELEAYHADGLLTHLRLAFSRDQKEKIYIQHKMNEDGKLLHKYLLDSQLSGHFYLCGPTWPAGDVKDAIVQSFMDGEQCAAIDANRIVNKLKEEERYVLEVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MJU4</accession>
    <name>A0A9P6MJU4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Sepiapterin reductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_005732</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002818">
        <property type="protein sequence ID" value="KAG0003808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MJU4"/>
    <dbReference type="OrthoDB" id="153074at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004757">
        <property type="term" value="F:sepiapterin reductase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006729">
        <property type="term" value="P:tetrahydrobiopterin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051721">
        <property type="entry name" value="Biopterin_syn/organic_redct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44085">
        <property type="entry name" value="SEPIAPTERIN REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44085:SF2">
        <property type="entry name" value="SEPIAPTERIN REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0003808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="281" mass="30561" checksum="53E0859E32198FE1" modified="2023-09-13" version="1">MSLSHHLVIITGANRGFGASVAHSYVTHSGANAISFVLVGRNQKGLEEVLSQLQHNASGSNVEVKGLVVGDVDLADIEKLDSNLPRIQAAATELRQESIQAKKIVTKSVLVNNAGSLGNLSKTAKDVTWQEARTYFDFNVVSLVGLCSAFLKSTQATFPKEQYPDHKTVVVNISSLLAVQAFSNWSLYAAGKAARDRLLGVIALEEKANNVKTLNYAPGPLDNDMQADVRRTLGDKEQLEIYDGMHKNGSLVKMDDSSRKLVMLLKKDEFASGGHIDFYDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MK05</accession>
    <name>A0A9P6MK05_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 9">Histone deacetylase</fullName>
            <ecNumber evidence="2 9">3.5.1.98</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">HOS2</name>
        <name evidence="15" type="ORF">BGZ80_005531</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>N(6)-acetyl-L-lysyl-[histone] + H2O = L-lysyl-[histone] + acetate</text>
            <dbReference type="Rhea" id="RHEA:58196"/>
            <dbReference type="Rhea" id="RHEA-COMP:9845"/>
            <dbReference type="Rhea" id="RHEA-COMP:11338"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
            <dbReference type="EC" id="3.5.1.98"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the histone deacetylase family. HD Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.98" evidence="2 9"/>
    <dbReference type="EMBL" id="JAAAID010002723">
        <property type="protein sequence ID" value="KAG0004959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MK05"/>
    <dbReference type="OrthoDB" id="1918432at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070210">
        <property type="term" value="C:Rpd3L-Expanded complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034967">
        <property type="term" value="C:Set3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141221">
        <property type="term" value="F:histone deacetylase activity, hydrolytic mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0040029">
        <property type="term" value="P:epigenetic regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.800.20:FF:000007">
        <property type="entry name" value="Histone deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.20">
        <property type="entry name" value="Histone deacetylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003084">
        <property type="entry name" value="HDAC_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000286">
        <property type="entry name" value="HDACs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023801">
        <property type="entry name" value="His_deacetylse_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037138">
        <property type="entry name" value="His_deacetylse_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625:SF36">
        <property type="entry name" value="HISTONE DEACETYLASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625">
        <property type="entry name" value="HISTONE DEACETYLASE HDAC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00850">
        <property type="entry name" value="Hist_deacetyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037913">
        <property type="entry name" value="His_deacetylse_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01270">
        <property type="entry name" value="HDASUPER"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01271">
        <property type="entry name" value="HISDACETLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="3 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 9" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Histone deacetylase" evidence="14">
        <location>
            <begin position="62"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="435"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="11"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="443"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="462"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="175"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="210"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="299"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="338"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR037913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR037913-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR037913-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR037913-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0004959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="476" mass="54289" checksum="611D23EDEA3B28E5" modified="2023-09-13" version="1">MSRRTVVNYEPDSTTSTFSTRSNALPTTRNSVASKRIGNHSNDIVAYFHDEEVGNYHYGERHPMKPHRLTLTNHLVISYDLDKKMEIFQPRRATEEEIMSFHAADYIDFLKRVTPENMNNFSKVFSRYNVGDDCPVFDGMFDFCKIYSGATIDAARKLTNGSADISINWSGGLHHAKRVEASGFCYVNDIVLGIFELLTHYPRVLYVDIDIHHGDGVQEAFYTTDRVMTVSFHKYNGDFFPGTGDIDEVGSGLGKHYSLNVPLKDGIDDESYIYLFKSVMEAVINSFRPSAIVLQCGADSLGCDRLGCFNLSIKAHGECVRFIKDFKLPLLVLGGGGYTIRNVARCWTYETSILVDHEVSNDLPYNEYIDYFQPDYKLHPHLSGKVENMNTRQYIRNLRIKVLEHLRFLDGAPSVQMQEIPPDIQGFLEMNDEEEAEILADSAKGKEEKEKQRGRDHGNDYYDNEQDVDMDMDIES</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MKA7</accession>
    <name>A0A9P6MKA7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_005265</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002602">
        <property type="protein sequence ID" value="KAG0006503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MKA7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="70"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="100"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0006503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="145" mass="16222" checksum="ACF528B65C49013F" modified="2023-09-13" version="1" fragment="single">MLKLYHKAGVLVYILAFVATFTTKYPKQFSVLMFTLKAALALTVIEVFFADDLSDEQWKLLENSWKVLQMWMVIFVAYLKFTFASSTKEESSDESAQTQTTDDTNNNIDNNNGSNNNDSSSNTNEQSPLLPSVKSNEPKSAGVDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MKU1</accession>
    <name>A0A9P6MKU1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Carrier domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_005370</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the NRP synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002651">
        <property type="protein sequence ID" value="KAG0005970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MKU1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043041">
        <property type="term" value="P:amino acid activation for nonribosomal peptide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05930">
        <property type="entry name" value="A_NRPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19544">
        <property type="entry name" value="E-C_NRPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.30:FF:000010">
        <property type="entry name" value="Enterobactin synthetase component F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12780:FF:000012">
        <property type="entry name" value="Non-ribosomal peptide synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.980:FF:000001">
        <property type="entry name" value="Non-ribosomal peptide synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1200.10:FF:000005">
        <property type="entry name" value="Nonribosomal peptide synthetase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.980">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.38.10">
        <property type="entry name" value="Luciferase, Domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001031">
        <property type="entry name" value="Thioesterase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF1">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00975">
        <property type="entry name" value="Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="958"/>
            <end position="1033"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0005970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1269" mass="140707" checksum="56DAF752D3D0B555" modified="2023-09-13" version="1" fragment="single">DIDLIVNQVEGGVANVQDIYALSPLQDGILFHHVMATKGDPYLLVTKMSFDSKDILDRYLDAVQKVVDRHDILRTAIVWEKLSTPAQVVLRHAKLLITELALDPADGDILDQLAKLTDPREHRIDLSQAPLIRFIMAQDVNGDHSTFEIMTAEIQAFMENKAQDLADPQPFRNLIFHVKSGISLDAHEDFFTKMLSEVDTPALPYGLSNVHHDGLDVTESHIMLPQDLNNRLRGHARRMGVSLASICHLAWAQVISRTSGQERVVFGTVIFGRMQGGSGSDQAMGLFINTLPIRIDIGERSIEESVRKSQIDLAALLEHEHASLALAQRCSSVPAGTPLFSSLLNYRHNIVSTAEVPDDIGVRVLDGEERTNYPFSISVEDGGSTLGLTAQVIKPFEPSRICEYMQQALQSIDDALQNNPEMPTRDLEILPPNEQQLLFQTWNATEREYLGSQCIHRLFELQALVAPTSRAVVFEDQELTYNELNGRANRLAHRLIELGVKPDMRVALCVDRSLAMIVGLLAILKAGGAYVPLDPAYPSDRLEYMLADASPVILLADDRGKAALRNASLDSLKILDPNLPSSQVVENPDVIGLTSRHLAYIIYTSGSTGKPKGVMIEHQGVVNQICTRPEIAGVGPTSQVLQFSSLSFDGSADEIFSALFYGGCLHVLPDRIRLDRAQLWEYLGDRSITQAELTPTFLQECSEFAPLSTNLTLILGGEALPPKLLRVMRTLIPHGTIVNAYGPTETTIEAIVWKCPDNFDGDTIPIGRPLPNKRAFVLDSYRKPVPIGAVGELYIAGAGMARGYLNRPDLTEKVFVPELFSTDKNSRMYKTGDLVRYDPDGSLVFLGRNDHQVKIRGFRIELGEIEERLCEHSTVREAVVLALGEGTSKRLVAYVVADYTDGLAHTLRAHISAKLPDYMVPTAFVRLDELPLNPNGKLDRQALPEPDMDSFVSQEYESPQGEIESSLAKIWAEILNVDRVGRHDNFFMLGGHSLLAIKMSSHIRSRMGMSMQLNALFEAPTVAELVPRILQQDATHENAFDVLLKLKPQGSRPPLFSIHPVFGLGWSYINLSKHLHPDQPLYALQSRGIGGNGKLAASFEEMVADYIDQIRHIQPRGPYHLLGWSFGGSVAQSMAVELKRLGEDVALLALMDTTAEYSSLPGDADITFDHDGDAYAEHLARSGNKNTLEEGRELWEKTRYVIKNNVKLSNEFSPSVYYGDMIFFSAIQSARVPDPSSWKPFILGKIEVHEVECEHLEMDRPGPMAEIGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MM35</accession>
    <name>A0A9P6MM35_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Malic enzyme</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_004905</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="7">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="7">Divalent metal cations. Prefers magnesium or manganese.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the malic enzymes family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002456">
        <property type="protein sequence ID" value="KAG0007238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MM35"/>
    <dbReference type="OrthoDB" id="5365701at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004471">
        <property type="term" value="F:malate dehydrogenase (decarboxylating) (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006108">
        <property type="term" value="P:malate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000182">
        <property type="entry name" value="NAD-dependent malic enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10380">
        <property type="entry name" value="Malic enzyme, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015884">
        <property type="entry name" value="Malic_enzyme_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012301">
        <property type="entry name" value="Malic_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037062">
        <property type="entry name" value="Malic_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012302">
        <property type="entry name" value="Malic_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001891">
        <property type="entry name" value="Malic_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF010052">
        <property type="entry name" value="PRK13529.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23406">
        <property type="entry name" value="MALIC ENZYME-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23406:SF32">
        <property type="entry name" value="NADP-DEPENDENT MALIC ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00390">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03949">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000106">
        <property type="entry name" value="ME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00072">
        <property type="entry name" value="MALOXRDTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01274">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00919">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00331">
        <property type="entry name" value="MALIC_ENZYMES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Malic enzyme N-terminal" evidence="10">
        <location>
            <begin position="78"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="Malic enzyme NAD-binding" evidence="9">
        <location>
            <begin position="280"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="101"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="184"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>(S)-malate</name>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="255"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="256"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="279"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="423"/>
        </location>
        <ligand>
            <name>(S)-malate</name>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="469"/>
        </location>
        <ligand>
            <name>(S)-malate</name>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000106-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000106-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000106-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0007238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="585" mass="63731" checksum="7857B4F82AB56B13" modified="2023-09-13" version="1">MTTATASQLNPQSIQQISKSSYLNQSTATPAELRAALNIQGLSPSRIETFDIQKKRALAQLRSKTSDIEKYIFLAWLRNTNVRLFYGLIADQLEETLPLIYTPTVGTACQNYSSIFPFLAPPGQPDGLFLSINDLPNLKQIIQNYKPYPQDPSLTPQITVITDGSRILGLGDLGVGGMGIPVGKLQLYVAGAGVDPRRTIPITLDLGTNNQAKLDDEFYLGLRQKRVGDDQFFPFVDAVIEALTSLYPKILIQFEDFSSEHAFQLLEKYQPKKFCFNDDIQGTGAVILAGFMNAIDLAGIPAKNHKILFFGAGSAAVGVAKQLADYFRNEHGMPEDEARGMVWLVDSKGLVTLDRGDKLAEHKLYFARKDNDGKQFPSIASVIDYVKPTALFGLSSQSGAFSEDVLKSMAALNERPIVFPLSNPAYQAECSFEQAMVHTKGKVIFASGTAFPKYTDPETGVVSAPGQGNNMYIFPGLGLGGILAQPANISDRLIYTAARACAHALTKEERSQGLLYPVLPRIRQVSAEVAAAVISEAVAEGTATNEEAINIVKKNDQKALLDYVHGNMWTTDGVHGDISDFAPHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMF9</accession>
    <name>A0A9P6MMF9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Transmembrane osmosensor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">SHO1_1</name>
        <name evidence="12" type="ORF">BGZ80_004736</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SHO1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002385">
        <property type="protein sequence ID" value="KAG0007365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMF9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007232">
        <property type="term" value="P:osmosensory signaling pathway via Sho1 osmosensor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030833">
        <property type="term" value="P:regulation of actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11855">
        <property type="entry name" value="SH3_Sho1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000213">
        <property type="entry name" value="High osmolarity signaling protein SHO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035522">
        <property type="entry name" value="Sho1_SH3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15735">
        <property type="entry name" value="FCH AND DOUBLE SH3 DOMAINS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15735:SF21">
        <property type="entry name" value="PROTEIN NERVOUS WRECK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="7" id="KW-0346">Stress response</keyword>
    <keyword evidence="5 10 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="30"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="11">
        <location>
            <begin position="132"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0007365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="191" mass="20929" checksum="59EB06D39EEDEF67" modified="2023-09-13" version="1">MIWVDIFYNLFLLLGVTLAVSTQSVQNYRLVILTFIGGSLSLLFGCISTAINAYGSQKYSAAGAGLIFQSFVLIFWVIYFGAEEDSLAKRSINGFTIPRTPLGAGSSGSANHDVVTPQQQPLNTVTVVPAKEYAYKARALYTYDANPEDNNELSFVKGEVLDIVDNQGKWWQARKQDGTVGIAPSNYLQLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNF5</accession>
    <name>A0A9P6MNF5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003602</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001964">
        <property type="protein sequence ID" value="KAG0008303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNF5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="487"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="268"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="288"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="318"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0008303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="912" mass="100739" checksum="92E13ACFB285B205" modified="2023-09-13" version="1">MKTPGTSSESTGPGGAESLDGTTLRPSLKRDASLIIPSMIPTQEVLQNLNLYRDNGMIQLGGDEDEIDDDIDSEDYHHSNHSPHSRNSDNGFVPSTYNDPDPVIQPNISKAKGATPLPPSSSGPSLFLRTYPRKRALSPRRAQAKLEAEDSDPIIDFDESDEDEELLHRTLPVSPHRPSKSLQGRSPQSPQLRRPLIPAESPSRRFIIPLATQPIRGNRHSPARASSATTVTRFGGERPAPDSPSKRLRPLSEIPRPIVPMHLQAQQSPSRRNSSSGSSGSPRKQRAGQLQPSSAVKSPSSRGMSTGMVVTTKSSSMAKPPKAIQPPAALGPQLQQIANEMRNGHAGEEQEQEEQEEEPLVRRRKGMGEARVEHESLFLSSPGMALLTSNFNSEPYAGSPELGPIAKKESGINQILGEHSLPVSSSSSAMELKKEALESPFWVPGPPAISSSKTTGQVCIKREESLTPVLARPEKVQKEVSSWTNLGAESSNTSRTPIHQQKLGQRADTPSLSDEIPLPGLILEFASKLTPLDHIKWPPAKVGRFHILGLVIFVNAEEKVVTKKGPTIAKREITICDQSATSFKLNLWAECCKWADCQFKAGDAVLITANSESTMSVMASTITGASLRASVTYKMLVIPGDEENEWEIGAVMQNGRSVKIQCCNYYIVKVLLVILYNNVNSINYRFVGMLVYIDASARKPSLLRESSWDDSLKSVKSRKFQSIKSLREHKFMGDAILDAYILAISSPDFFLDDGDERAKFDFIQCYCTVCQSIAVSSPQNPSILFCRECQLSQKRDPPLEWRYPAFELSLGDKPRMGANLTSECIQLRCQSEIGDQVFVSVPARRWMRDREGFWESRARWKRLVELMNRQGENVVGDDERDSEASDNNAQKLRVEVKVGVNMMVKALKVEYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPI1</accession>
    <name>A0A9P6MPI1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_003017</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001776">
        <property type="protein sequence ID" value="KAG0008819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPI1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myb-like" evidence="2">
        <location>
            <begin position="317"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="244"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="294"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0008819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="451" mass="51240" checksum="31D24D7DBDB57EF6" modified="2023-09-13" version="1">MPGSWTQGPSSLHPSGRDQCSDLTVNGEGERSTIFSNISSFRDTLPKALPPRVAKENLERLRQRLQRRRARARETILVDLHQGVRSVEAEVHRQVEMVFSRLKEAPASKYAFALTNSFLAQIPATLSQSISGSGPTDVETSVAAERKRNEDRITTERLSKEFDSIALTSHSERSPQSRMIEISDEESRVSISRLGASEVLSASMHTSYSTACSQVLSAALPSFIPSMVAPLVCVFAYPGPLSAANPQAEHTDDRTGPKHHHHQQQQQQQQQQPSKELNLPWGSPGRSPFPSTTVDDRRQDPKRQIPDPGILILDSRSWTQAEQEALYLAATRFHLSGQWSKIREMMNLHRTDEEIEVEYTRLYGHREDKDTDNDEDEDDLQVGAMDEDADDEAEIEINAVFMKFGGQRRQHQYHHTPRLRCDGREKEPIRLFRRELMIDKRFTLEEIPTRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPZ4</accession>
    <name>A0A9P6MPZ4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Oligopeptide transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_002034</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001490">
        <property type="protein sequence ID" value="KAG0009814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPZ4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035673">
        <property type="term" value="F:oligopeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004648">
        <property type="entry name" value="Oligpept_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22601">
        <property type="entry name" value="ISP4 LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="153"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="216"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="251"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0009814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="272" mass="30493" checksum="9DBB96C0F3EC04AA" modified="2023-09-13" version="1" fragment="single">MSEQKHEYTTEKEFVDEKFDIERSSVVLEEEENSPIPEVAAIVPNTDDPSLPTLTFRFWVMATGFSVIISFCNQFFWFRENPITIGMSVVQLLAYPLGKFMARILPSGILNPGPFNIKEHVLIALAANCAAGTAYAVDIIVIQRVFYEQNFGFLANFLLILTTQMLGFGLAGVLRRYLVYPAAMVWPANLVQVALFNTLHQDEQLAPGQWSRYKFFLVAFAAIFVYEWIPTFLFPVIGSIAWICWAKPDSILAAQIGGAYGLGVGAITLDWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPZ9</accession>
    <name>A0A9P6MPZ9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">JmjC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_002663</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001666">
        <property type="protein sequence ID" value="KAG0009177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPZ9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02373">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="1">
        <location>
            <begin position="71"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0009177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="291" mass="33365" checksum="130E0A746BC58EAD" modified="2023-09-13" version="1" fragment="single">MGKNFTPVQRININNMGDLELIDKVNEIVVKNGTPLILENLKKNNKWNAKLFTLEHLERHHGEEEIICRDLTNSVDKNSYNIESAAENLMVYIGRHGTWTPTHFDHCGAIGHNVMLWADKGSSSIWFMIATEDMSRAETLWESFGQNIEFENYFASVQDLAQADFPIHVLEQHVGDLVLIPSLGYHQVGKTTIKAAWNRLTTHCLNAAINVVLPRYKRATSSMTFTEHFTMDTLQTLYLSAIKKWNTSSVLASCESYSQITEEWIYSMVNYKYSDTSLAYLKHQQLKLPKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQ81</accession>
    <name>A0A9P6MQ81_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">[histone H3]-trimethyl-L-lysine(4) demethylase</fullName>
            <ecNumber evidence="4">1.14.11.67</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BGZ80_002474</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + 3 2-oxoglutarate + 3 O2 = L-lysyl(4)-[histone H3] + 3 formaldehyde + 3 succinate + 3 CO2</text>
            <dbReference type="Rhea" id="RHEA:60208"/>
            <dbReference type="Rhea" id="RHEA-COMP:15537"/>
            <dbReference type="Rhea" id="RHEA-COMP:15547"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:16842"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:61961"/>
            <dbReference type="EC" id="1.14.11.67"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the JARID1 histone demethylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.11.67" evidence="4"/>
    <dbReference type="EMBL" id="JAAAID010001611">
        <property type="protein sequence ID" value="KAG0009360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQ81"/>
    <dbReference type="OrthoDB" id="1678912at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034647">
        <property type="term" value="F:histone H3K4me/H3K4me2/H3K4me3 demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16100">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.60:FF:000016">
        <property type="entry name" value="Putative Lysine-specific demethylase 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.60">
        <property type="entry name" value="ARID DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001606">
        <property type="entry name" value="ARID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036431">
        <property type="entry name" value="ARID_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003349">
        <property type="entry name" value="JmjN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048615">
        <property type="entry name" value="KDM5_C-hel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004198">
        <property type="entry name" value="Znf_C5HC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10694">
        <property type="entry name" value="LYSINE-SPECIFIC DEMETHYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10694:SF33">
        <property type="entry name" value="LYSINE-SPECIFIC DEMETHYLASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01388">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02373">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02375">
        <property type="entry name" value="JmjN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21323">
        <property type="entry name" value="KDM5_C-hel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02928">
        <property type="entry name" value="zf-C5HC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01014">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00501">
        <property type="entry name" value="BRIGHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00545">
        <property type="entry name" value="JmjN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46774">
        <property type="entry name" value="ARID-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51011">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51183">
        <property type="entry name" value="JMJN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 12" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="JmjN" evidence="16">
        <location>
            <begin position="64"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="ARID" evidence="15">
        <location>
            <begin position="129"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="14">
        <location>
            <begin position="321"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="JmjC" evidence="17">
        <location>
            <begin position="457"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="226"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="287"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAG0009360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="756" mass="85803" checksum="3B15957B3E56D192" modified="2023-09-13" version="1">MMKKAVPRPAVQAVDTATTSVPLDIPHVPVQKAPALDMSTVNTTAPPENPRTNPPTRIFGLQDAPCFYPTAEEFVEPLKYIEHIRPEAEKAGICKIIPPEGWKPPFALDTEVFRFKTRIQKLNSMEGQTRTNLNYLEQLYKFHRQQGHPVYKIPQLDKRPIDLFQLRKEVTARGGYHKVTASKKWAEIGRGLNYTRKQCTSMSNALKNAYLNIILPYEIYLAKHKPANSASSSPGVTAGTKREASTDESIDGGQGLATPAASPPSCNDILPAPTRRSKRIKKEPTSYADSTPSSPARSQSDRMSTEPSPVKGEENMADNPKAICELCHVGGHLNKMLICDGCELGHHTFCLSPPLQHIPKTDWYCPKCLIAGEDFGFEEGEEYSLSSFQQKCDKFKKEYFEKDGYADGKVPEDVIEREFWRLVENAFETVEVEYGADLHSSQYGSGFPMKTRDPHDEYSTHPSNLNNMPVLQESLFRHIKSDISGMMVPWLYVGMCFSTFCWHNEDHYTYSINYMHWGATKTWYGVPASDALKFEDTMRQAVPELFEQQPDLLFQLVTMLSPGRLVENGVKVLALDQRPGQFVVTFPQAYHAGFNQGFNFAEAVNFAPPDWCQFGVDCAMRYKEHRKHPVFSHDELIITTALKDDSVDTAKWLRHEMKDLLKREMELRRKALKQYPSMRVVVEEVDRPEEEMQCQFCNSYIYLSQVACSCGPKVVCSDHISELCKCDESEHFLRLRLSDEQLESIEKRVSDIAAST</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQ99</accession>
    <name>A0A9P6MQ99_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001822</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001425">
        <property type="protein sequence ID" value="KAG0010058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQ99"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0010058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="57" mass="6286" checksum="C8E111279E509CB9" modified="2023-09-13" version="1" fragment="single">MSQQIDNPGLDYQVDHHQPIQSTVTEVAPETTPADPIARRERSSSDSAEKPKNDIPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQA7</accession>
    <name>A0A9P6MQA7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">MHD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_002390</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001588">
        <property type="protein sequence ID" value="KAG0009435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQA7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028565">
        <property type="entry name" value="MHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018808">
        <property type="entry name" value="Muniscin_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10291">
        <property type="entry name" value="muHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51072">
        <property type="entry name" value="MHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MHD" evidence="2">
        <location>
            <begin position="193"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0009435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="470" mass="50175" checksum="EF0A9E77B191761D" modified="2023-09-13" version="1">MLMEIKQDTVAESTDEARAALERVASTLKQTKTVSRRHPGRREVRSMYQSEDSVNAFNSLHSSPLSSTYTPDSPFANSPASRVINTAGTHQSSTAFSPAGSRATTLGLPIGSNPAQSQFPPTLPLPPTNGTETGTGAVAAAAAVPAVIIDQSLSTEPGSVFSSGSSVPGSPTAASPIAATPSNGAVVAGAGQKQTWVVSVIEKVHVHTQSGEVAKMMVTGDVIMNLEGSDIDPELPKRAVLRLGQLQALDKYVPNHIFLTAKDGTEGAYWVNLEMVSQAMQQNGQSQGMPVLKYQVKINDEESKHKMMPLLIQPNWKCEPHQTSLLVNYKANAHCGLSMESQGENGDASGNVYLSDLSFLVPVSGEVVNVQSKPTGVWSRDSKKMLWDVDNVLMSRTSPEPHKLLARFEMNPSGGASQPSPTAAKFRVHGKLLSEVNIHLEKEAEGEEETNVALGQVRLQVQSGRYLAMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQG5</accession>
    <name>A0A9P6MQG5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BGZ80_002417</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the OSBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001597">
        <property type="protein sequence ID" value="KAG0009408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQG5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097038">
        <property type="term" value="C:perinuclear endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032934">
        <property type="term" value="F:sterol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120009">
        <property type="term" value="P:intermembrane lipid transfer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030011">
        <property type="term" value="P:maintenance of cell polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000061">
        <property type="entry name" value="Oxysterol binding protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.160.120:FF:000001">
        <property type="entry name" value="Oxysterol-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037239">
        <property type="entry name" value="OSBP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000648">
        <property type="entry name" value="Oxysterol-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018494">
        <property type="entry name" value="Oxysterol-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972:SF205">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01237">
        <property type="entry name" value="Oxysterol_BP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144000">
        <property type="entry name" value="Oxysterol-binding protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01013">
        <property type="entry name" value="OSBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="7" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="ANK" evidence="8">
        <location>
            <begin position="90"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="11">
        <location>
            <begin position="151"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="269"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="426"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="520"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="295"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="489"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0009408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1030" mass="115652" checksum="C6CD2A82CFA965EA" modified="2023-09-13" version="1">MGRLDVVKLLLSKNDVNDGILDHKGKSAFDVASTAEVRVVLKAHRTEYLTQTTALMHQFAESGDLTSLMSLFDHPRAAFVLNISHQNTETGSTILHAASRRKDMAMVRWCLDQGIDTLLRDKKGKTAADVSKDSKIKRSDAPLVPTTPGQPPKLEGTLFKWTNYASGYKARWFVLEDGILSYFHNQEDAGNACRGSINLGIAKVWIDSSDKQRFDIIGKGSIRYHLKAGHANEAKRWILAITQSKQWIEDTSGNDRLSLVESRQSINLSATDYPRQKGNESTLSRGRTLLKERTPSATRSQRSRSSSTSPEDNQMEENTLPHAESFVTMNNYIQTQIQIQSEFTENLIRLQRAAEVSEGSEIMKLTLAAHESSLAVKSSIQKLYEMTQDRENYWKKILQQESQKRELWEESLRVLSEEQLEMQRILKRTEETNRKMRKNRSVRSRASTPTLNAGKASTPGSSTVTPAPEATEAGKLTSVPQKAPSEGEQSVEDESDVESGDEFFDAVSDDDIVEFDNDDVEEGDHVSDAGDAEGSGKEGGALATVTSSKPGEPYIAPSFKGYPEKLRERLPTKQTSLRPDVSLWAILKNSVGKDLSKITLPVYFNEPTSMLQRMAEDAEYIELLDKAARQRGATERILFIAAFAMSNYSSTIGRVAKPFNPLLGETYEYCREDKQFRYISEQVSHHPPISACYCDSPNYNFYAEVDVKSKFWGKSFEVLPKGTSHVELKVPKAFAEGSSELLTDPDDENKFIEHYSWRKVTTCVQNLIVGTPWIDSYGDMIITNHRTGETCKMTFKPRGWRGKDAYEIRGFAADGNGKEVWEVAGRWNDRLVARLAGKGNGEDLGSDAVAAGAVHVTDDHSGVPHHSKSRSGVYASSISPKQVLLLWKRDPVPPNPTPFNLTPFAMTLNDCPEELKKHLCPTDSRLRPDQRAMENAEFDLANTEKQRLEEKQRAKRRLLPPGKEHQPRWFKRNAQDDGWDFIGRDLPGQPKGSGAARDGRTSYWVERERCGATADYPEQLKWDIDDDDIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQN9</accession>
    <name>A0A9P6MQN9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HECT-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="4">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BGZ80_001828</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 16">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the UPL family. TOM1/PTR1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="4"/>
    <dbReference type="EMBL" id="JAAAID010001427">
        <property type="protein sequence ID" value="KAG0010054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00078">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1750.10:FF:000026">
        <property type="entry name" value="E3 ubiquitin-protein ligase HACE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2410.10:FF:000004">
        <property type="entry name" value="E3 ubiquitin-protein ligase HUWE1, variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2160.10:FF:000001">
        <property type="entry name" value="E3 ubiquitin-protein ligase NEDD4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1750.10:FF:000003">
        <property type="entry name" value="E3 ubiquitin-protein ligase UPL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2160.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050409">
        <property type="entry name" value="E3_ubiq-protein_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025527">
        <property type="entry name" value="HUWE1/Rev1_UBM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11254:SF67">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE HUWE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11254">
        <property type="entry name" value="HECT DOMAIN UBIQUITIN-PROTEIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14377">
        <property type="entry name" value="UBM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <keyword evidence="7 11" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="HECT" evidence="13">
        <location>
            <begin position="1706"/>
            <end position="2042"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="34"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="291"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="828"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1281"/>
            <end position="1387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="338"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="390"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="404"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="436"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="449"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="466"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="485"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="501"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="828"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="877"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1285"/>
            <end position="1302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1309"/>
            <end position="1343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1345"/>
            <end position="1369"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="11">
        <location>
            <position position="2009"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="2042"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00034494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0010054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="2042" mass="225626" checksum="5AB6D8CBF4581F58" modified="2023-09-13" version="1" fragment="single">AKKYSSEISETVIHFLVSQLLSVRAVPTVTFASQSPTTTTAGGLPAKATSSHTAGADKDPKATEDIPHDADFVHRCFLLQCLNELLLSYPSCKVDLMNYSRRRGSKDATSAASKPRANWLSYLLNDLIPYKGTVTQSSETELRKHSIESNFASSVLVAMCSNSNDEEEKKPFSSLVQVRRFIIDGIIRSFKEAIASSDPVEVKYGKFLSLSELSYKIFGSSSSAAAAGTKASEDMSVNIVKVMLEKNFIMTLTNVLADIDLNYPHARVLVNAVLKPLEHLTKISLKMSRAAEPGATKIHRQATPLSRTGSGAGSGDDADTPDLYRNSSLGMFDGANMESEEDEEDDDSAGEDDIFEGDEYDEETASDASDLSEEDFSEDDEDDGEALEEVIDRNPFHHQSHEISDDEDNDDEDMGGDEDDLDEEMEAELQEALGNGDDDEDEEMMEWDADSRPVTIRESDIAEIIGGDDEPQVADPEYYDEQDRAHRHHTHTHNPHLHAADEDDGMDEDEDEDGDEDEEGDEDEDVDEDDLDEEEDDIVLLDDAEGFDPVRGPGRGGPWDMTSTFVLNDQDGLMNGAQIIDLRGRRPRSSGRRIDDRGFLWNDAGIDQGRFSYIDDDEFPSLGAPARNPFLQVSDNVITHPLLSQPRAASTSATGNAHRRGGSRGVGLTDWQAFGELLTGNTSQILGTLMNGGAIHASHGAFRVEVGNGNAAIVTPIDRSIPHGNIIGNGTAVGVPANSPADTASTNKADMFSIVHDFVPFSTSQRWSQECRMMYGGAAQDKASRLVNHIINALIPAAKEEHRLKLERDAKELERRRIEAERRRAAEEKRKAEEEAERLKAEEAEKARLAEEAAEAEREAARRAEEAAARAARGEVDEPTTTEDSAMEVEGSAAAAAEEEAASEPAAPERRTVMIDGELVDITDSDIDPEFLEALPEDMRREVYNDYLQTHRPAPTSSQPPVSSSETQAINSDFLDALPQSMRSELEDIIHAQGAASSNSSGSDQLLSAFNEYTLSRLVPQLRQLYQGRGGGSVMPSAILAETSALLDQIPRHYPGLREARDILAGASGSTSAAAKKTVVPRDAIQLVDKSSLATLVRLMFLPQPLSKNILNKLLVNLCENSKTRAELLSLLLSILQDGGADLAAVDKSFAQMSLRGKTVIKAHHHHKGKGTATLPTQVPVAMDNVPNLVARRCFEALYYIVSSNSQAVLFFLTEHENVTLKRSPSKKGKGKEKAVSSKYPIVLLLDLLERPIFVENSALMEQLMTLLSVICKPLAVLAKDEEEEKRKKEEEEKEKKEREEQQMEEQTESAATTSADVTTDATAGSESTAPAAAEQGAAVPAESSGPTPATEEGSSSTIEVVTSEQPASESKPDAKAVDAEPPTLKPPAIPDHCVQLIVRVLTAGECSSRTFQYTLSVIQNLSVLEGTRDVITAELVRVARELGAGILEDLHELSQTLANAMSGVDVQGVALEKFSPASSGQAKLLRVLKTIDYMYSRKQGLTPPATTQVNIELAPTLDPEEADAVTPRSMRDVNQGIFKLSKDEEKVSAIYDSLSFQSLWTTIGDTLEQIRERSDMIHVATVLLPLIECFMVVCKYVGQRYSTLEVDDAVVKADSNATEELFLQFTEKHSKILNIMVRNNPALMSGSFSLLVHNPKMMEFDNKRNYFTQQLHKRNPTREHYGTLQMNVRREMVFVDSFNQLQSRSGDEFKYSKLNVHFHGEEGVDAGGVTREWFQVLARQMFNPDYALFTTSAADKLTYQPNRASSVNSDHLLFFKFIGRVIGKAIYDGRLLDAYFTRSFYKHILGRPVDYRDVEAVDPEYYKSLVWILENNITDIVEETFSVETDDFGNNRIVDLKPNGRNIPVTEENKHEYVKYITEQKLTLAIKDQIHAFLQGFHEIIPAHLISIFNEQELELLISGLPDIDVDEWKNNTEYQNYTPGSPQIQNFWRAVRSFDQTERAKLLQFVTGTSKVPLGGFSQLQGISGIQKFQIHKDFSSTKRLPSAHTCFNQLDLPEYETYEELRQQLLTAISECSTGFAFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRQ8</accession>
    <name>A0A9P6MRQ8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transcription initiation factor IIE subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_001557</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Tetramer of two alpha and two beta chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the TFIIE beta subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001359">
        <property type="protein sequence ID" value="KAG0010351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRQ8"/>
    <dbReference type="OrthoDB" id="3907302at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005673">
        <property type="term" value="C:transcription factor TFIIE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001097">
        <property type="term" value="F:TFIIH-class transcription factor complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054600">
        <property type="entry name" value="TFA2_E-tether"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040501">
        <property type="entry name" value="TFA2_Winged_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016656">
        <property type="entry name" value="TFIIE-bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003166">
        <property type="entry name" value="TFIIE_bsu_DNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12716:SF8">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIE SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12716">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIE, BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22254">
        <property type="entry name" value="TFA2_E-tether"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18121">
        <property type="entry name" value="TFA2_Winged_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02186">
        <property type="entry name" value="TFIIE_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016398">
        <property type="entry name" value="TFIIE-beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51351">
        <property type="entry name" value="TFIIE_BETA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 7" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TFIIE beta" evidence="9">
        <location>
            <begin position="66"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="37"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="40"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR016398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0010351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="284" mass="32609" checksum="102FC59A6FB40178" modified="2023-09-13" version="1">MAHFKNATSEFKKRLADQPIIKRAVVTPLASSGLDDGPLYTSSNANPNNNGTQVFRSSKKKKTEIYSQPQDTGIGKHINSLLLNAINFLKTSDEPLSIEDLKRKGNIDLEAKPELFQLLKANEKVLYDQMNGTFVYKPTYHIKSKEDLLMILEKRKNEGGMDFKELKDSYSKLAQSVEELANEGRILVIRNKDGNPRVLFWNDQRYNTAMDKEFRDIWHSLRITDEIDLSKELQKAGLTHMQVYDKKGPGEAPKRKPVRRNRKVKITNTHMKGLDLTKDFVMQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRT7</accession>
    <name>A0A9P6MRT7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 10">Fructose-bisphosphate aldolase</fullName>
            <shortName evidence="10">FBP aldolase</shortName>
            <ecNumber evidence="5 10">4.1.2.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">FBA1_1</name>
        <name evidence="11" type="ORF">BGZ80_001344</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 10">Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:14729"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.1.2.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="10">Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the class II fructose-bisphosphate aldolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.13" evidence="5 10"/>
    <dbReference type="EMBL" id="JAAAID010001300">
        <property type="protein sequence ID" value="KAG0010611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRT7"/>
    <dbReference type="OrthoDB" id="35652at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004332">
        <property type="term" value="F:fructose-bisphosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00946">
        <property type="entry name" value="FBP_aldolase_IIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000013">
        <property type="entry name" value="Class II fructose-bisphosphate aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000771">
        <property type="entry name" value="FBA_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006411">
        <property type="entry name" value="Fruct_bisP_bact"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00167">
        <property type="entry name" value="cbbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01520">
        <property type="entry name" value="FruBisAldo_II_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006628">
        <property type="entry name" value="PRK09197.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30559:SF0">
        <property type="entry name" value="FRUCTOSE-BISPHOSPHATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30559">
        <property type="entry name" value="FRUCTOSE-BISPHOSPHATE ALDOLASE CLASS 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01116">
        <property type="entry name" value="F_bP_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001359">
        <property type="entry name" value="F_bP_aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00602">
        <property type="entry name" value="ALDOLASE_CLASS_II_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00806">
        <property type="entry name" value="ALDOLASE_CLASS_II_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="9 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU366023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0010611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="358" mass="39377" checksum="197A8BC576111E67" modified="2023-09-13" version="1">MGLLDIVPSGVITGDDVRKVYSYASKHGFAIPAINCTSSSTINAALEAARDVKSAIIIQFSNGGAAYYAGKGISNKDQQASILGAVAGAHHVRAVAKSYGIPVILHSDHCAKNLLPWFDGMLAADEEYFAKHGEPLFSSHMLDLSEESKEENIEICVRYLERMAKINCHLEMEIGITGGEEDGVDNSDVDNASLYTQPQDILDIYNAFSKITDLFSIAAAFGNVHGVYAPGNVKLHPELLGKHQAYVKEELKLESDKPVWFVFHGGSGSTEEDIRVAVSLGVVKMNVDTDTQWAYWEGIKQFYEAKKAYLQGQVGNPEGENKPNKKFYDPRVWVREAEKTMVTRVQQACKDLGNVERL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRZ9</accession>
    <name>A0A9P6MRZ9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">G-protein coupled receptors family 2 profile 2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_000564</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor Fz/Smo family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001119">
        <property type="protein sequence ID" value="KAG0011592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRZ9"/>
    <dbReference type="OrthoDB" id="26203at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007166">
        <property type="term" value="P:cell surface receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.2000.10">
        <property type="entry name" value="Frizzled cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000539">
        <property type="entry name" value="Frizzled/Smoothened_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036790">
        <property type="entry name" value="Frizzled_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017981">
        <property type="entry name" value="GPCR_2-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053247">
        <property type="entry name" value="GPCR_GPR1/git3-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42058:SF1">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 2 PROFILE 2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42058">
        <property type="entry name" value="G_PROTEIN_RECEP_F2_4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01534">
        <property type="entry name" value="Frizzled"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63501">
        <property type="entry name" value="Frizzled cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50261">
        <property type="entry name" value="G_PROTEIN_RECEP_F2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040346104" description="G-protein coupled receptors family 2 profile 2 domain-containing protein" evidence="8">
        <location>
            <begin position="25"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="237"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="268"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="309"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="350"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="390"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="452"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="517"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 2 profile 2" evidence="9">
        <location>
            <begin position="228"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0011592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="574" mass="62709" checksum="C7BE22442A5415DB" modified="2023-09-13" version="1">MSRLMTKVATLATLALGFFNTIDAIGSAANYNGTLCADYVDYVVWVAPGLNMSYIEQSLVAQGMTKDALALLPESCLGTLMQYACSSAYPRIEATNQTGTYDVRFACKSTCEADVSACSSILTLAGKANLVPNCDSYIPGTTTTVPPGVLFQPDGTCNVVTSKSAPKTTTGNQTTGTTTGTATSACPAPFITDPMSGAGNTTANSDYCDLGCCLPCPAQYSLYHTDVLKTGYTITNIMRLISMILSFVVMVSYIFLPDKRSHPSALILYFSTCVFLFSVVVIFPLVNTRGMQCFDAINPSTQQNNLKCAIQGAILIFASIGTCSWCSALILNLHMHTVWNSAWFAKKYWLIHFVCWGYATAITAAALGMGQVKWEFATLCLISQEKSSSMFFYPMAAIIFPAFLVHVATFIHIARISAQAGVDSETMSRSTLSAGAAAVISHRRHVMMAIKIQWRAAVMAIFAILCVMFYWLFYFLQLKKIKPDTLKPHVRVFAVCLAQGTAHNTCADQLAPYLPPYGLMIAAEFLVSMIGSVIFIVFFKMTLFQEWGDWFGSISYLLGGKKRQQKEQDQFFVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MS17</accession>
    <name>A0A9P6MS17_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA repair protein xrcc2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">XRCC2</name>
        <name evidence="2" type="ORF">BGZ80_001287</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001291">
        <property type="protein sequence ID" value="KAG0010654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MS17"/>
    <dbReference type="OrthoDB" id="420422at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005815">
        <property type="term" value="C:microtubule organizing center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033063">
        <property type="term" value="C:Rad51B-Rad51C-Rad51D-XRCC2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005657">
        <property type="term" value="C:replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000400">
        <property type="term" value="F:four-way junction DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042148">
        <property type="term" value="P:DNA strand invasion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030547">
        <property type="entry name" value="XRCC2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46644">
        <property type="entry name" value="DNA REPAIR PROTEIN XRCC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46644:SF2">
        <property type="entry name" value="DNA REPAIR PROTEIN XRCC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0010654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="474" mass="54253" checksum="00F92CA3C32BA627" modified="2023-09-13" version="1">MLPSHRERLFQVQQESGLDFIQSLHEPAEYAPRLHHSRIVEPTTTASRADLNVAYHATAQPRTAHTSSLAGIPPGTSSIHATAGQNLGLDGIDSILDRYGLLQPGDMIDFYGPSCCGKTLYLYAIIISTILPRSWKYSKSKPAVLLNGKARSVIFLDMEQGFSVDRLRSLLYLEIIARLGLYEENEKTKAQNQPNNGGEKDETHDRQEILDVEEGRNIEQTGEREDNEVSREEQQYRWQESYHIDTQSPEMQSKIEQLMLSCLRNVHLFRPQDAISAIVILRTLDQYLASNTRVGSSSTSISNASPPFAILMIDSLSSFYWQERASNNHTRFTTVLIDALNRLVPRWKLIFISTTWSLPSRTLATDRTVTDALRARFRYRFLMQPRTLDRFDSEDDLVREWIKRQRERQQQKHMQRERGAKENVTGVVDNRDEYTGSVFQAQMLIPSVEHTRQELFRFSISDAAGVCSFNVPVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSG5</accession>
    <name>A0A9P6MSG5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_001106</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001247">
        <property type="protein sequence ID" value="KAG0010895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSG5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="142"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="443"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="464"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0010895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="479" mass="53311" checksum="4F56CEF2489112D3" modified="2023-09-13" version="1" fragment="single">MAAVHALDCGTRVDIVGRPGPDYFAQLRQFLRRNFKAYVLIGSVHYLVNRRGIFAWPSIILGLLATQQYLRYKGVQHSLFKLVFVTIFIGPRWAVWLVQVSIQQQLFLHELLQPYLARVQFKVWEEKAWWAEHELELQGFAFGVWIVCSIPVIGVAAIPVMFPAVAFLLSRSCGLMENSGNGVSGDIIEKRTPGIKAVALNKSKAVAGNWNSTRVETFVQNLTLKTNKPVQHLEVTAVYHDVDDGVEGAVSGDQALAEKELSIAKKTELYLARQRQEKQREQNRAIYEYMAERQANAPLPRVAPIASTTFNGTTTQALGVALASAPTLTPSTPVAINETAAQESPASSEYVEATRLNDLTSYNFSDRKTLETAPSAPPEPSFIPPLISDDIQGWTNYLSENDVYRVESATDDSLPISSANPTVDSVDSAFLDVEQETQKRIKVQEIGIQEDANRQREGANQQPEEARRQQEARQQRGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MT04</accession>
    <name>A0A9P6MT04_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Actin patch assembly and actin polymerization protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">LSB5_1</name>
        <name evidence="6" type="ORF">BGZ80_000455</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001096">
        <property type="protein sequence ID" value="KAG0011735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MT04"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051666">
        <property type="term" value="P:actin cortical patch localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007034">
        <property type="term" value="P:vacuolar transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd21383">
        <property type="entry name" value="GAT_GGA_Tom1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16980">
        <property type="entry name" value="VHS_Lsb5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004152">
        <property type="entry name" value="GAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038425">
        <property type="entry name" value="GAT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045007">
        <property type="entry name" value="LSB5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002014">
        <property type="entry name" value="VHS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47789">
        <property type="entry name" value="LAS SEVENTEEN-BINDING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47789:SF2">
        <property type="entry name" value="VHS DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03127">
        <property type="entry name" value="GAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00790">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00288">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89009">
        <property type="entry name" value="GAT-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50909">
        <property type="entry name" value="GAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50179">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0653">Protein transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="VHS" evidence="4">
        <location>
            <begin position="25"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="GAT" evidence="5">
        <location>
            <begin position="161"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="360"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="371"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0011735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="393" mass="43328" checksum="26F4C0791A70A5A8" modified="2023-09-13" version="1">MGLFAKNNTIDALIDIIVEQVVITNWETLQTLCQQVNSTDDGAKQASKALRRKFREGSAQKQMNAITVTQGLIDRCGSKFKAQMVTAKFMEALRVALFSSDTNQYVRARLMERLFAWSQEFSQDPGMVAILQLYSRAKGDPELASLIPAQSPPRSTMPSEQRTVQILQDIEVANNNAHMLIEAISFADPELEAVEENELIKEFHSKCQTLHGGIRIYLNEVTASVAPNEKCLAGLLNSNEELIRALAAYDHMMERNSLDKASRIINTEHVPPALEYQIVEYLDNGAGVGAGYITISSNGKDKHTIGGQATFDPFADDAYYVSDITTAIKNEYGKRPAFAEESDRIINSEQEQRMIQLTKERSLMDESRNGSSSSSSAAPATTAVAHPVVASTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MT58</accession>
    <name>A0A9P6MT58_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Carboxypeptidase</fullName>
            <ecNumber evidence="7">3.4.16.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_000237</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase S10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.-" evidence="7"/>
    <dbReference type="EMBL" id="JAAAID010001042">
        <property type="protein sequence ID" value="KAG0012058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MT58"/>
    <dbReference type="OrthoDB" id="443318at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018202">
        <property type="entry name" value="Ser_caboxypep_ser_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802:SF472">
        <property type="entry name" value="SERINE CARBOXYPEPTIDASE CPVL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00724">
        <property type="entry name" value="CRBOXYPTASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00131">
        <property type="entry name" value="CARBOXYPEPT_SER_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040544421" description="Carboxypeptidase" evidence="7">
        <location>
            <begin position="22"/>
            <end position="590"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0012058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="590" mass="66364" checksum="2CB9B92BCD8A39BD" modified="2023-09-13" version="1">MFGEKPLAFAILVLSTSCTLAFVADKPQSAFLKNGAGDFYESSASEHAVFKHAAWSQPCANGYHNNGYEFKNCASLLREEHRVGTLPWEDGHEPIFESYAGHLPIRSWKQDGYHGETNIWLQGGPGSSSMIGLFFENGPIRVNAKMKLERVPVSWADEYSILFIDQPVGTGYSYVTRLKDADNLEVTDDETIQKILAKLDDELHRDQLEEQELFEGLSGQDLYFKSAVSRDHQLKTQAPLYSYGYVKNERGVAADLLVFLDKFYQRYPEVQKADLYLTGESYAGKYVPALAYGIMESNKDRRRRHEGYESGDGDDDDMAGNQIIFPLKGIALGNSLTDPVTQVQIHADHAYFLGLITHSQSEVMRALQDQSVEEALKGRFLESNKYRGSVFELFENATGNLNPYDIRKGSIPNDWSRMEAFMNLDDVKNSLNIFGPRTEFLKENDVPEEEIKRIQEGRAKVKFSKDPVVLKTMSGDIMKSASWMVSSLLKQGIKVLAFQGVFDFRDAVAGSNSWIEMLEWPGQEEFLDAEREIWINDGKLAGYVTQVEGLSRVVILGAGHLAPMDQGENSFAMIKSLVEGTRLNQESFSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MT85</accession>
    <name>A0A9P6MT85_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">[histone H3]-lysine(36) N-trimethyltransferase</fullName>
            <ecNumber evidence="3">2.1.1.359</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">SET2</name>
        <name evidence="16" type="ORF">BGZ80_000278</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
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        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
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            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">NRRL 2769</strain>
        </source>
    </reference>
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        <subcellularLocation>
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        </subcellularLocation>
        <subcellularLocation>
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        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTB4</accession>
    <name>A0A9P6MTB4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RNA polymerase-associated factor</fullName>
        </submittedName>
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        <name evidence="7" type="primary">PAF1</name>
        <name evidence="7" type="ORF">BGZ80_000231</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PAF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001041">
        <property type="protein sequence ID" value="KAG0012061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000993">
        <property type="term" value="F:RNA polymerase II complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="PIGH-H_dom"/>
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    <dbReference type="InterPro" id="IPR007133">
        <property type="entry name" value="RNA_pol_II-assoc_Paf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23188">
        <property type="entry name" value="RNA POLYMERASE II-ASSOCIATED FACTOR 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23188:SF12">
        <property type="entry name" value="RNA POLYMERASE II-ASSOCIATED FACTOR 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03985">
        <property type="entry name" value="Paf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10181">
        <property type="entry name" value="PIG-H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040280754" evidence="5">
        <location>
            <begin position="18"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatidylinositol N-acetylglucosaminyltransferase subunit H conserved" evidence="6">
        <location>
            <begin position="26"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="338"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="339"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF10181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0012061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="503" mass="56466" checksum="C1C7AF4CA6D6E4BE" modified="2023-09-13" version="1">MTCYAIIALLIVSRLMVKFFMVTEETILVIRDVGVQVKTVYLGGRSSSRFIDRSKISDIIINEAITMLHIRVYMAIIVEGEDKMVVVFQLHFPHMSQPVHKKKFGSEFLCKTRYRNTLPLPPFAPKLLALPSSTERCIKFQSTGLNESTANEMILDNQLAIPIDLIEMRENYFGEGRQHHHENGSLANGTLNQIDEMLLTVPLKAASGIPAANGVIAGGSSAGLVVPNKHRLPVVSWLRRTEYISSETPTGAGKGAYKENNVGKKKNMVIDNSREGQIAAIEKTFERFSKVSEEKFLAGLRHPTKPGLTAVESLPVFPDFSIWGNDYTLVTFDVDPEMTNDRSSRSQDEGNRAQRSSNALIKPMHNANDPETWLAYYLPDMDTAKEINHRKRSRAQLAASGLNADDDDEDSKEISFSLQRDYTYTTIPCASLSQLVFTFRDDAETKQKAAFYNPMQSKLMLRKKRAKRYEDDDPPITHIDVTGRRMNSDELAAKRDALEAIGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTU7</accession>
    <name>A0A9P6MTU7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Guanine nucleotide exchange factor vps9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_011126</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000857">
        <property type="protein sequence ID" value="KAG0013355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTU7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030139">
        <property type="term" value="C:endocytic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14279">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.80">
        <property type="entry name" value="VPS9 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003892">
        <property type="entry name" value="CUE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041545">
        <property type="entry name" value="DUF5601"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003123">
        <property type="entry name" value="VPS9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045046">
        <property type="entry name" value="Vps9-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037191">
        <property type="entry name" value="VPS9_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23101:SF25">
        <property type="entry name" value="GTPASE-ACTIVATING PROTEIN AND VPS9 DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23101">
        <property type="entry name" value="RAB GDP/GTP EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18151">
        <property type="entry name" value="DUF5601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00167">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109993">
        <property type="entry name" value="VPS9 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51140">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51205">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VPS9" evidence="3">
        <location>
            <begin position="374"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="domain" description="CUE" evidence="2">
        <location>
            <begin position="727"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="506"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="565"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="620"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="515"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="576"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="632"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="663"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="680"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="697"/>
            <end position="725"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0013355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="769" mass="86238" checksum="E0D6ACF3AEF0D0DD" modified="2023-09-13" version="1">MSLRDDDIQDQLTETLQQTRLSNSSDSQIATTDTKTDTSIAGAEMNSAKNSDEQREEANTHDKDKNSDEYRIEDSNNKDSSSVSFVTPLEATSSSKDSAQTSKLERRKSSLSTTGSRLKRSQSAEKHVTIIDSEATKGHDEQTSEVKAQEEAATKEELSKILMQFDPLVESNQKKADEEETTVTIMDRGLFFNDTRSNAKSAAISPSLTPSPQILDSPKSSHDVLVATSEKTKSSSSKKKSESRQRSSQSQDSSRGGDKESTSSPVSRSEPSKPKDIPFDFHKFLEQMGHRSAIPITRYFRSFLKEFERKPWTVNEQIKIIQDFLDFIAVKMEACDLWKNSTDQEFENVKEGMEKLVMNRLFIHTFSPSTTDDAERDEVLSQKIRIFRWIKEEHLDIPHSPHNDSYLNNAQAELKKINGYKAPRDKVICILNCCKYIFILRSNPPNLVSNVQNPDKLQAEAGYYLASLMGAISFIENLEASSLSISPEEFDQQIGKTMSELNQEKVDAMATETASRASSPDSQSSGHRKQGSKLATLVAGTAATRGNRQQQQQQQPPINEKQYLAAESAHQEKASSRSSHSPTGSSILNPATLIERGANFATKTIQKPLDLIEKMFQDSGDHEEMAKPYPPRSSQQHYQQQSANAPPPLPNRYNQQQQQQLQGPSNADGNDSFTEFVYVPAGQQAQQLSPQQPNPMHPQQQQQYYQQGYPAEQAAQQQQQQQRSEPQYLQELEMLTEMFPKCEREVCRVVLQANDGRISPSIDTLLAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MU14</accession>
    <name>A0A9P6MU14_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_010908</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000811">
        <property type="protein sequence ID" value="KAG0013709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MU14"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005834">
        <property type="term" value="C:heterotrimeric G-protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001664">
        <property type="term" value="F:G protein-coupled receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031683">
        <property type="term" value="F:G-protein beta/gamma-subunit complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007186">
        <property type="term" value="P:G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000750">
        <property type="term" value="P:pheromone-dependent signal transduction involved in conjugation with cellular fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00066">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000563">
        <property type="entry name" value="Guanine nucleotide-binding protein alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.400.10">
        <property type="entry name" value="GI Alpha 1, domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002975">
        <property type="entry name" value="Fungi_Gprotein_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001019">
        <property type="entry name" value="Gprotein_alpha_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011025">
        <property type="entry name" value="GproteinA_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218">
        <property type="entry name" value="GTP-BINDING PROTEIN ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218:SF242">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-1 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00503">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00318">
        <property type="entry name" value="GPROTEINA"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01241">
        <property type="entry name" value="GPROTEINAFNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00275">
        <property type="entry name" value="G_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47895">
        <property type="entry name" value="Transducin (alpha subunit), insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51882">
        <property type="entry name" value="G_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0807">Transducer</keyword>
    <feature type="binding site" evidence="7">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="124"/>
            <end position="128"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="193"/>
            <end position="196"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="250"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0013709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="277" mass="31873" checksum="5AFE8EE66F72CDD9" modified="2023-09-13" version="1">MVGAMQAILNAMQEHGVSLTYQENYKYVPVFATSPRISNGAPYPPQYQQALKALWSDPSVRQAYHLGHTYALADNVKYFFDAVDRLYAPGYVPDDSDILRCRVKSTGITETTFYIGSLTYRMFDVGGQRSERKKWIHCFEGVTAVLFLVAISGYDQCLVEDKDANQMEEAMMLFDQICNSQWFVETSMILFLNKMDIFRVKIKYSSIKNYFPDYDGPDDSVAEATEFFRKRFTRLNRSEHKEVYVHQTDATDTNLLRNIMSSVNDIILARNIRALAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MU18</accession>
    <name>A0A9P6MU18_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_011314</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000898">
        <property type="protein sequence ID" value="KAG0013048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MU18"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0013048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="230" mass="24600" checksum="B1351F310F0B734B" modified="2023-09-13" version="1">MDSPARKGLRDHSQSSNGHGQTLSVSSSTAGTATDTCNNNTTTTGILPDLALFSPSDPNLQPYSTNSAAIFHDAIAARMARIKRSFLPSTSSSAFSHSSTNSSSFPLSSSSSHELHSPPGCVLPVQIDIYSLGVMFYYTWASYSTFLREDLTPGTIAEGLNSFASGHGLTVAGSGACLPSTPIRLANVIHKMVAKSSRDRFLSMIQVRKELTAIRDQEQEAQKKEAELKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUI3</accession>
    <name>A0A9P6MUI3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_011209</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000874">
        <property type="protein sequence ID" value="KAG0013242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUI3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="213"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="29"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="159"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0013242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="280" mass="30507" checksum="424A24DC5D3BAF8D" modified="2023-09-13" version="1">MAREINVELGSDESMASLLESVAAERRSATTTQTRTSQHPPFSSASRSFWSSSNSGVRLHRTLRRSARLLEASTSVFASAASRPTSSPSYPYASTTQEPRISEDFNRYVGSHGIQSDQHPRLVQHIAQKLSESRRVVNQNFVAIEKFYISFQFGRDSTKASATASGSSSNSKTTNQALTPWTCPPNIRSLNIQGKLPRYLDPPEVVVLSANHSGTQHQTGGNGATTSSSSSPPKGLTNGKGHGTKLESWLRAAFIRLWHGWIAVAAGILDNISYIEMPKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUJ2</accession>
    <name>A0A9P6MUJ2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF2433 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_010590</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000753">
        <property type="protein sequence ID" value="KAG0014189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUJ2"/>
    <dbReference type="OrthoDB" id="3918848at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018829">
        <property type="entry name" value="DUF2433"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052743">
        <property type="entry name" value="Glutaminase_GtaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31987:SF11">
        <property type="entry name" value="DUF2433 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31987">
        <property type="entry name" value="GLUTAMINASE A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10360">
        <property type="entry name" value="DUF2433"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2433" evidence="1">
        <location>
            <begin position="254"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0014189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="382" mass="41907" checksum="579D970371850403" modified="2023-09-13" version="1">MNSPTPQAINTPAGKVLCVADLRGNISQLNDLVDQTGAKLIIHCGDFGFYERDSLNRISDRTLKHLVQYSTLIPPALRTRLLQSTVTPDSLRTQIRASATNILSELPLYLSGQKSLKVPVYTVWGACEDVSVLEKFRSSEYSINNLHIIDESSTVVIDIGGVKLRLFGLGGAIAQHKLFDIGEGTTTIAGGSGTMWTTALQIGQLVDTAQKVFDATETRILISHASPGREGILAQLALVLKADFTISAGLHFRYGISYNEFGVQGDQELYRNKLLNSQKNFMDMWEGIKTQVESNISDEQKILLENCLSVVNRLPAVNTLPNDKDEAAFKNMWNFNLPDAASGLLLLDINQGKIATETRSQGFNFSYRRNNVSLRSGSPAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUY6</accession>
    <name>A0A9P6MUY6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ion transport domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_011124</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000856">
        <property type="protein sequence ID" value="KAG0013361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005216">
        <property type="term" value="F:monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098703">
        <property type="term" value="P:calcium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024862">
        <property type="entry name" value="TRPV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10582:SF2">
        <property type="entry name" value="INACTIVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10582">
        <property type="entry name" value="TRANSIENT RECEPTOR POTENTIAL ION CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1311"/>
            <end position="1334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1360"/>
            <end position="1383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1428"/>
            <end position="1446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1467"/>
            <end position="1483"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1495"/>
            <end position="1519"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="411"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="924"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1001"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1656"/>
            <end position="1773"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1911"/>
            <end position="1960"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="944"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1006"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1682"/>
            <end position="1698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1712"/>
            <end position="1727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1745"/>
            <end position="1754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1917"/>
            <end position="1926"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0013361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1960" mass="220813" checksum="90B46A611563F7B6" modified="2023-09-13" version="1">MFWKNDKASDSTLQLQVINYSPDMNPVNTSSPPTESQSVPLQNIDRMDVATEKAPKSRRINDPCSTAYESWVAFVLHSPATFLLLESFGYFTSENRYLHWQERLVTHHMILVQHRPDIVAHIPIKTSAFKFVANFPGFSTGHYTIGWRVKATKDFCIPNGLHFVVNVSYDTEPDISGTLDVIMPAHKLNMLVKERWYNLVLEEKLVIQPHIGKSRVQVILRNNENVERVDFFGFVIEHVEIRPISLPKENQVWDMSVVKNPNNPNKGIKNVYSGCATVAIDHIGVGDLPIGLSISSNGDQVAIFQEPKIGEWAEGSNVEKATFPFKLFNNPLVPQSSFVLNIDTPSDNNANEKTATVPADNSFASNIATPIEPMQLTEVRSNYGILRTFIGYGQFLPEMKKGDWEKNDVNSALNSTADGEGEGGDARASSSKNSASQMNSMFVACNGLYLDAFEISSEKKWKRKHTITLADLLPTLSRRITCKLMMESISSGTFMWLEDGGRSCTIWNLLTGSNITHISSIENAAFKGPTFRGHSKMAISPHESIVALASVDGSLTTYFANTGMAIDDINFPGYKIEYVGFHSQDDQLFVILRNSTTFELTAKILDTLQLKSQTMTNQVPIPSIGQTILAFFYTKGFWNRGIICEPDAAKINFYISYQPTSSKVAKGNPKVVKASPDDVVYESRHHENIQYRLMTGIHRELLPEGDGVSYWVLRVEVVEEDLEKRSQRVIFSFVPEPWMRISTSEVSHPENLQSVFFVPCGTRFAVVGVQTLQIWNLPTRENPKCSLQFFWSQPRDEDSFESGDIEHKSGRVRDYYMETQGITIFMDTETSNTTAEVKMNDKFRKLVVPLPGIGTISARLAILHCFRSIHLLAAAFAFSHRESAKVARTEAQVTFTYEEHCDAIVRFTREHINRMMSIGVYSPKKRRLSPAISSQPNPSRPRKDKGDELADPDTPKPDDPDSSRLADPDTTKLADLDTIKPVASTIGEARKPTIIGENITIHANANRHDDDDHDQDDRIRPAPKRVKHKHVLHGRSGGPKPRNSEVVTILTLLLDHPYLQRANHIFVEGLLNTANGDWIPRDNKVLNPIKRAIEARNGQLVMAFIDYCIKNAKKYHPSYLMPAVQCLNELSDRYPTILADMFRRASYVPAHNHVYVSSHAIIANPQMGSWLAFKLKFWNMFLGKKWEKSNIVNDYQKPVFSLRSQLPFRASSRFNVLSIETSARERRVERFPPKMDMVMEKEREMKSEYSHKIYVAPFPKLSMYGPYRPWFKDLAKAKSAFVEIAGQDYFDSPAMIATLAFKWHKFGFKFWLLRFSVAMIFFVLVIIITARQIYTSTLPDPITDLTYSNLISRYLDDDGWPAVIMTTIGIGSILVIYEFLQFLDSPRNYVTSPYNYTDLAAYVTPIIGCILLVRQDPNPDPSQEQGPSQVWVMSFAILFLYMNILFELRVIRELGIVVNIILNITRRIVWFFLIFALFLAGRWDPVDTSFDNNNASFHIMMVIFFFFTTILLLNILIALMNDAFNESKDQGQLVWLKQWSEVIAEVEVFLMTQSTRQNRNYFPDFIYYGASEQEAELYESKFSITDKSNLSIENRYLVETLEDEQSAAQQTQRALLRDVQALTKELKGMKQTQDGFNNDLTKITELMAAFIAQTSGMSPLSPRTEPSSQVSPIENDPHPSNASPTTPPGTAVGTPSTPGGFGLATPGGSTPGGASKFAAAAQRRAGGTLNEPTIPASVRRKISPSAPQTESPTAYSPLVQFNPPRSSTQSSTATAELTSLSGLPGREATTLPMMASSSAPYRVGSVPEPGASALDGRTLAKQRIQQKLAEIHTMDDALRGGYRSVEDNNASHPIYVKAPDRRLNDDDMLYDSDEERVETEIRKMTPVHHQTYYASSSSSHQHQDMFQYHFQTQSQSETHEHPKRTQSDTVVPVVPHETIPLHARPPQASPEDPPRNEDRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MV52</accession>
    <name>A0A9P6MV52_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BGZ80_010719</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Nudix hydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000779">
        <property type="protein sequence ID" value="KAG0013989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MV52"/>
    <dbReference type="OrthoDB" id="410307at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004081">
        <property type="term" value="F:bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006167">
        <property type="term" value="P:AMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006754">
        <property type="term" value="P:ATP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051252">
        <property type="term" value="P:regulation of RNA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd03428">
        <property type="entry name" value="NUDIX_Ap4A_Nudt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11561">
        <property type="entry name" value="W2_eIF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.1000.10:FF:000003">
        <property type="entry name" value="Zinc finger CCCH domain-containing protein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051325">
        <property type="entry name" value="Nudix_hydrolase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003565">
        <property type="entry name" value="Tetra_PHTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003307">
        <property type="entry name" value="W2_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21340:SF0">
        <property type="entry name" value="BIS(5'-NUCLEOSYL)-TETRAPHOSPHATASE [ASYMMETRICAL]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21340">
        <property type="entry name" value="DIADENOSINE 5,5-P1,P4-TETRAPHOSPHATE PYROPHOSPHOHYDROLASE MUTT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02020">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00515">
        <property type="entry name" value="eIF5C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51363">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="13">
        <location>
            <begin position="3"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="11">
        <location>
            <begin position="215"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="11">
        <location>
            <begin position="278"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="domain" description="W2" evidence="12">
        <location>
            <begin position="537"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="9">
        <location>
            <begin position="215"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="9">
        <location>
            <begin position="278"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="146"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="187"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="249"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="314"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="193"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="257"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="368"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="386"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="442"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="489"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="508"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0013989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="691" mass="78577" checksum="31611475F4412B5B" modified="2023-09-13" version="1">MDKSLHVTGILIYRHQRNSTEILLVNDSFNHKRHWTAPKGRVIGDEDELKAALRETLEITGLSVKDLKVEDSFRAEIKYLSGTRPKRVVYYLAELIDSAKVLPTGEGLQFAWCNLQQATDKALYRTMQDVLRSAFTAAETSRARALAAAPPKMHRNHSNNGDSLESNMKNLNIALPLDSQRQAITRDYNNRGGSRDRDHNRDGGSGGHSHADNPNYKTRLCERFEAEQFCPYYGKCTFAHGLAELRQRPVNPDQDKPQSAVQASYQNRAKRETTENEFHKTRLCERFMNDGECPFGSRCTYAHGREELRQRAGYQNNNNAGNNGGYGGNGQNRTYPRDGQSGERSYRSNNEGYQDRNLRHQQQQGEGSEDRPYRTNRSEGPYRSTFADRENRDGPYRPPQALEQERSLRSQSDSSSPTGAYRVPQARNQVPDEGSMSRSVLAPRATISSPAATPAATNATSSAAPSPKGTSPAGTPVLGSDKSTNNRRRVQEVDNKPRAKVVEMTSEDMEKFQLRRPETPVAAKPDSKQAQRDQLIQDLQKFFQNNQQQGVTQDKKQQQQQLQDEIKEVTRLEMRNALTKAQLYYILIASLFTETSVETWKKVLQEKEKLLANFVRSSEDQLTLMRAWEQLFVKHRPNMMARAPIVMKGLYDVELVEEDVMLSWYDLPTTDAELKKKCVVFVEWLRSAEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVD2</accession>
    <name>A0A9P6MVD2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Nucleotide-binding protein-like</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BGZ80_010092</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the Mrp/NBP35 ATP-binding proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000667">
        <property type="protein sequence ID" value="KAG0015027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVD2"/>
    <dbReference type="OrthoDB" id="1741334at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140663">
        <property type="term" value="F:ATP-dependent FeS chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032981">
        <property type="term" value="P:mitochondrial respiratory chain complex I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02037">
        <property type="entry name" value="Mrp_NBP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000709">
        <property type="entry name" value="Iron-sulfur protein NUBPL isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02040">
        <property type="entry name" value="Mrp_NBP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019591">
        <property type="entry name" value="Mrp/NBP35_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044304">
        <property type="entry name" value="NUBPL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033756">
        <property type="entry name" value="YlxH/NBP35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42961">
        <property type="entry name" value="IRON-SULFUR PROTEIN NUBPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42961:SF2">
        <property type="entry name" value="IRON-SULFUR PROTEIN NUBPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10609">
        <property type="entry name" value="ParA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="38"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00081370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0015027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="335" mass="35975" checksum="26E932BDFD21DFA1" modified="2023-09-13" version="1">MSSTIAFRRAALRLEGRPLPLWTCKAKRFISTSGSILHENPLGIPRKPPTPAPGRGSGPAPSIPRMQRGLPQKMPIKGVKHIIAVASGKGGVGKSTTSVNLALAIAGMNKRVGLLDADIFGPSIPRLMNLSGEPELTGTEDRLVPLTNFGVKCMSMGFLVGEEAPVVWRGLMVMKALQQLLHQVEWGDLDLLVIDMPPGTGDTQLTISQQIPLSGVVIVSTPQDIALIDARKGVNMFKKVNVPILGVVQNMSLHVCPNCNHESHIFGDGGAERTAKEMELDFLGDVALHSEICQLSDKGQPVVVSRPDSKHTQYYKAIASKVVAKLWPETKLASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVD4</accession>
    <name>A0A9P6MVD4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_010190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000684">
        <property type="protein sequence ID" value="KAG0014852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVD4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0014852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="203" mass="23500" checksum="8B69F98E639F7C95" modified="2023-09-13" version="1">MSYPQFTISTTFTREIQGLDKYFSDFNSPTKSVKKQAEEVLRLKLANHKKSLAQARYFINNETGLYEELDRMQEESNPEDSEVEQETEPEDLDDEQDELESEELQDEQQSDLQDVQDALQCFLSNPKGHELNSLSRTKCMQTVSTKRVVEPKPGSIRNTEFTQDDPVDNDESVNPLAISCRSYVVSRYFQKDTRKGSQKRHSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVR2</accession>
    <name>A0A9P6MVR2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glutathione s-transferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_010526</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000741">
        <property type="protein sequence ID" value="KAG0014296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVR2"/>
    <dbReference type="OrthoDB" id="414243at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050213">
        <property type="entry name" value="GST_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571:SF150">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14497">
        <property type="entry name" value="GST_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="23"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="2">
        <location>
            <begin position="106"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0014296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="243" mass="26867" checksum="7E1A54566A935C58" modified="2023-09-13" version="1">MVHPFFDPAQAAAFNELALKRDSTFELKYFGFHGLALTSRIILVVSGAKFTNVIPTDWAAEKTLTPFGVVPLLKEISVDGKITINVAESDAIDRYLAKKFGMAGDNAFEETVINSYLNNSIGMILQIYLKVFAVRDPALKAEAKEQLSNGPIPTWIKFFEQHLSDNGSNGHLVGNKITLPDIKTAHLVDIINVVKEGTITEESHPSLMKVKTTLDSIPALKAWRATDEYKAFSEFNLQHLGFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWM7</accession>
    <name>A0A9P6MWM7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_009169</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000527">
        <property type="protein sequence ID" value="KAG0016511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWM7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0016511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="170" mass="17024" checksum="B6807CC02EC9D8A8" modified="2023-09-13" version="1">MFFNLTNIARLYACYVFCTFAAIASPLSVIPGGPNLGGPNPGGPILGGPILGGLGSPGSIIGPTTFATTQSNVIANTDVAPQVDVAPTIPILCSDPYSVPVPVASGYPYPVPADSCGQWGSGGAFGNCGGFGSGFAFSQQPHGSEFCDFGDLDSLWGSGNFGSFGKFGGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWZ7</accession>
    <name>A0A9P6MWZ7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_008871</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000498">
        <property type="protein sequence ID" value="KAG0016834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWZ7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0016834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="134" mass="15143" checksum="600157E2081A7809" modified="2023-09-13" version="1">MFVVSFNEDNTIRMIGAPNQILPPIKEAIKKHWNLISGMGYTQHYDSWQLILDGQPFRPHGKDTVQLRMMLLQLLATIKARGYRLETGFSKNTDVDGCRFARGGCVDIIFENVASSRSKYVDDKEGSFAAAFLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXC8</accession>
    <name>A0A9P6MXC8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_009350</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000550">
        <property type="protein sequence ID" value="KAG0016247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXC8"/>
    <dbReference type="OrthoDB" id="1367865at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034967">
        <property type="term" value="C:Set3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.960.30:FF:000001">
        <property type="entry name" value="F-box-like/WD repeat-containing protein TBL1XR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.960.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045183">
        <property type="entry name" value="Ebi-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006594">
        <property type="entry name" value="LisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22846:SF2">
        <property type="entry name" value="F-BOX-LIKE_WD REPEAT-CONTAINING PROTEIN EBI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22846">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08513">
        <property type="entry name" value="LisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00667">
        <property type="entry name" value="LisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50896">
        <property type="entry name" value="LISH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="172"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="92"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0016247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="239" mass="26674" checksum="B3A792C075D99F08" modified="2023-09-13" version="1" fragment="single">MSVTSEEINYLIFRYLQESGFVHTGFAFQNESHIHKSDYRNANVQPGALVSVLQKGLLYMDLELHVNEDGSERECTGPVALIGPHRCDKQLKKAKRDELGGRGNKRDRKESKRSQKQQDREKRTKLEVDEDANEEDMMDTDQIEDVSVVGTPAETADIPEVKVIPASDAISLRGHTADVFVCSWNPASPSLLASGAGDATARLWQIPTSAEETLQDPIVLKHLPSLTDNNRDVTTMDWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXE8</accession>
    <name>A0A9P6MXE8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">NEDD8-activating enzyme E1 regulatory subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">NAE1</name>
        <name evidence="7" type="ORF">BGZ80_008267</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 5">Protein modification; protein neddylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000443">
        <property type="protein sequence ID" value="KAG0017453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXE8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019781">
        <property type="term" value="F:NEDD8 activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045116">
        <property type="term" value="P:protein neddylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01493">
        <property type="entry name" value="APPBP1_RUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000475">
        <property type="entry name" value="NEDD8-activating enzyme E1 regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030667">
        <property type="entry name" value="APP-BP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953:SF29">
        <property type="entry name" value="NEDD8-ACTIVATING ENZYME E1 REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039099">
        <property type="entry name" value="APP-BP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="THIF-type NAD/FAD binding fold" evidence="6">
        <location>
            <begin position="8"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR039099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0017453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="539" mass="59664" checksum="6C784858C88B504E" modified="2023-09-13" version="1">MDAKTQKYDRQLRLWGNSGQDALESAHILLINATAVGCEILKNLVLPGIGQFTVVDQGTVTQNDIGSNFFLDYESLGKSRAERACGLLGELNEDVKGHWVAKDILTVLKENPGYLAQFSMVIASDITRETAEKIAALCWVNGHDANANPGSSSPAGKKRTAFVWVKTVGLVGAPRIAVPEHAIVETHPDNVADLRIDTPFPELSEYAKSFNFETQDGLEFGHIPYVAILLKYMEEWKQAHGGKIPSTYAEKNQLKANIRSGMRSADDENFEEAINSVLRSCQPTVVPSAIKELFSDSKCENLTAESSNFWILTRAVRDFVNDDSKSSGLLPLSGTIPDMKAQTDSYVTLQSIYKTKAKQDVQEVSKNVESLLESLGLAPGSISLQEIESFCKYSAFLKVIRYRSLEDEYRQPKTNNIASWLSDPDSVFPHYVLLRASDSFYDDHGRYPGEGENWEDDVDQLQANVNTLLQSWGIEGNTISKDLTHEICRYGNGSIHNIASFIGGVVSQEIIKLITHQYIPMDNTFIFDGARSVSAVFAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXW6</accession>
    <name>A0A9P6MXW6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_007694</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000399">
        <property type="protein sequence ID" value="KAG0017969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXW6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0017969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="86" mass="9510" checksum="7F7D5C15A09D2CD4" modified="2023-09-13" version="1">MVPKVQAEGVEWDLEGGEGENRLDNAEKAPLALMLYYYNCCCESSLKALAHQVCQKDDMVDEVIAVDFEQKDVPSPLGPGSGFERM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYU8</accession>
    <name>A0A9P6MYU8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Prefoldin subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_008270</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the prefoldin subunit beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000443">
        <property type="protein sequence ID" value="KAG0017456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYU8"/>
    <dbReference type="OrthoDB" id="2015447at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016272">
        <property type="term" value="C:prefoldin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044183">
        <property type="term" value="F:protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002777">
        <property type="entry name" value="PFD_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009053">
        <property type="entry name" value="Prefoldin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20903:SF0">
        <property type="entry name" value="PREFOLDIN SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20903">
        <property type="entry name" value="PREFOLDIN SUBUNIT 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01920">
        <property type="entry name" value="Prefoldin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46579">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0017456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="124" mass="14344" checksum="598063313E1033B5" modified="2023-09-13" version="1">MSINEQALGKIVHDLQSKLQEATRMVASVQAQIQTREREKRLSELTNKELLALQPDTVTYKSVGKMFIQEPLTDLTKELSTRSKEMESDMEALDKKRIYWERNKTEAQGNLQELIRQIQQAQAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZB8</accession>
    <name>A0A9P6MZB8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ubiquitin-like modifier-activating enzyme ATG7</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7 9">ATG12-activating enzyme E1 ATG7</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Autophagy-related protein 7</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Ubiquitin-like modifier-activating enzyme atg7</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ATG7</name>
        <name evidence="12" type="ORF">BGZ80_007167</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATG7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000362">
        <property type="protein sequence ID" value="KAG0018442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZB8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000407">
        <property type="term" value="C:phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019778">
        <property type="term" value="F:Atg12 activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019779">
        <property type="term" value="F:Atg8 activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006995">
        <property type="term" value="P:cellular response to nitrogen starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032446">
        <property type="term" value="P:protein modification by small protein conjugation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.140.70:FF:000001">
        <property type="entry name" value="Ubiquitin-like modifier-activating enzyme atg7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.100">
        <property type="entry name" value="Ubiquitin-like modifier-activating enzyme ATG7 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.70">
        <property type="entry name" value="Ubiquitin-like modifier-activating enzyme ATG7 N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032197">
        <property type="entry name" value="Atg7_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042522">
        <property type="entry name" value="Atg7_N_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042523">
        <property type="entry name" value="Atg7_N_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953:SF3">
        <property type="entry name" value="UBIQUITIN-LIKE MODIFIER-ACTIVATING ENZYME ATG7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16420">
        <property type="entry name" value="ATG7_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0072">Autophagy</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Ubiquitin-like modifier-activating enzyme Atg7 N-terminal" evidence="11">
        <location>
            <begin position="3"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="domain" description="THIF-type NAD/FAD binding fold" evidence="10">
        <location>
            <begin position="339"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF16420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0018442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="622" mass="69083" checksum="76E17B2E3F29396A" modified="2023-09-13" version="1">MVLQFHPWASAVEAPFWQVLTQRKMDIFKLDDSLKPIQGYYFTGQQARIPGTDTTVDMPARLCLGTGAFPDDHNQSNRTPAFTFPAPGIVKNTNTIEDFKSIDKTALFKTTVDQIWDDITSGRAVADPSLLNKFLLLTFADLKKFKFFYWFAFPALQSDPAWTADAMQDITAIWSPAKISNLNTQIDQYRQTNLPSQSGFFLVKETHDTVAVARLQDWASFFAGCDESQIIVGFADPSSLDSNPGWPLRNLLALIQYQWKITKVRVLCFREVPGRQDINASKIFTAQVPFYVPVTGCPKAVGWEKNAQGKLGPRLADLAPLMDPTRLADTAVDLNLKLMRWRLLPDLQLEKVQETRCLLLGAGTLGCYVARSLLGWGVRNITFVDNAKVSFSNPVRQPLFEFEDCLEGGKDKAKTAAASLRKIYPGVIVINAALGFDTFLVMRHGIGQDHEHHASAGSLPLGCYFCNDVVAPTDSLSDRTLDQQCTVTRPGLSAIASAMAVEMMVSLLHHPDGVRAPADKADGEGDQDSAQDRIGSALGLLPHQIRGFLSRFKNLLISGQAYDRCTACSDAILEAYDQRGFEFLARVFQDAKHLEDVTGLTKMKEESEDLDMEWAEDSEEDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZZ8</accession>
    <name>A0A9P6MZZ8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004537</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000230">
        <property type="protein sequence ID" value="KAG0020246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZZ8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BHLH" evidence="1">
        <location>
            <begin position="77"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0020246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="106" mass="11798" checksum="11EB6F14B5064B8F" modified="2023-09-13" version="1">MSGFNDIEQRRSSYPARHELVHQGHGSVPQALDSAMDVYGHQRTTDLHHVSRPGPVSATARILHKSSTREVAAVGPNRRLAHILSEQKRREKINGGFDELKSVVPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0G1</accession>
    <name>A0A9P6N0G1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zinc fyve domain containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005540</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000273">
        <property type="protein sequence ID" value="KAG0019613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0G1"/>
    <dbReference type="OrthoDB" id="5407799at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032154">
        <property type="term" value="C:cleavage furrow"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030496">
        <property type="term" value="C:midbody"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032266">
        <property type="term" value="F:phosphatidylinositol-3-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009838">
        <property type="term" value="P:abscission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044878">
        <property type="term" value="P:mitotic cytokinesis checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19817">
        <property type="entry name" value="Bbox1_ANCHR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044553">
        <property type="entry name" value="Bbox1_ANCHR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46603">
        <property type="entry name" value="ABSCISSION/NOCUT CHECKPOINT REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46603:SF1">
        <property type="entry name" value="ABSCISSION_NOCUT CHECKPOINT REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22586">
        <property type="entry name" value="ANCHR-like_BBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57845">
        <property type="entry name" value="B-box zinc-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0019613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="384" mass="42705" checksum="2F971BF5FD273497" modified="2023-09-13" version="1">MSSSNNLPDDSISDKELELRLAKLKATEAENIPSSDHDLAVHFSKVFGHSPAATHLSPSLENTHYQQNFEDETGEGQTRPKLGSTPSQQSTSSYFIPATSDLSQEEVRVDFEHIDRILADSKDLLVDESDNDDLGFLDDLDTFSPTQTQQLKETLRGENKKLGEQELNNVTKDLERTLSKFLQTHQQPSIDFQNSAGTELMGINNNSISIHQAEDSDQERAFGNQLDRIAGVSLSSGMGDDDEASRLITQAREAAQLEDKYGDIDEGLLKDLNSRHEELKKGIQSLSYILPQNSTRSVRFTIEDLGLGPPPAAVGLDELRGGDDDNENPDNWCCICNEDATWTCPGCDNDNYCEGCFRESHIGADSDWEMKKHRPRPFVKNVAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0N3</accession>
    <name>A0A9P6N0N3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="6">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_005719</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the PPP phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="6"/>
    <dbReference type="EMBL" id="JAAAID010000281">
        <property type="protein sequence ID" value="KAG0019511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0N3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07415">
        <property type="entry name" value="MPP_PP2A_PP4_PP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000047">
        <property type="entry name" value="NADP-dependent L-serine/L-allo-threonine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047129">
        <property type="entry name" value="PPA2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45619">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0464">Manganese</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="7">
        <location>
            <begin position="91"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0019511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="508" mass="56960" checksum="8FD91A21D743443B" modified="2023-09-13" version="1">MSLTDVSDVEGWIQHLMQCKQLPEADIKRLCEKAREILMEESNVQPVRCPVTVCGDIHGQFHDLMELFRIGGNSPDTNYLFMGDYDRVTILRGNHESRQITQVYGFYDECLRKYGNANVWKAFTDLFDYLPLTALIEDQVNDKAMLAVLIFCLHGGLSPSIDSLDHIRSLDRIQEVPHEGPMCDLLWSDPDDRCGWGISPRGAGYTFGQDVSETFNHNNGLTLIARAHQLVMEGYNWCQDRNVVTIFSAPNYCYRCGNQAAIMEIDEHLKYTFLQFDPAPRRGEPHLLSARRKERLDKLKQELESRHPNIKVSTFELDVRNRAKVQATAANFGDVDVLVNNAGLVIGLEKLEDITEEAMDTMIDTNVKGLVHVTQSVLPGMRARNKGHIINIGSVAGQQPYANGSIYCASKAAVASITRALLYETVDTAIRISEINPGMVETEFSVVRFKGDKDKADSVYKGLQPLNGDDIAETIIFVANRPEHANIAEMLVFPTNQAAATTVYRKAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0Q3</accession>
    <name>A0A9P6N0Q3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Peptidase A1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BGZ80_005624</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000277">
        <property type="protein sequence ID" value="KAG0019550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0Q3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.70.10:FF:000008">
        <property type="entry name" value="Cathepsin D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF51">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="7 8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 9" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0865">Zymogen</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="491"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="12">
        <location>
            <begin position="158"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="456"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="461"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="189"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0019550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="516" mass="54452" checksum="DED9EFAE444BA372" modified="2023-09-13" version="1">MSTPWTPTRTLRQQRTKPATHPVASRSSERIPTSMASDPITCNCNIGSQSSVNSPLYPTSSSLYPSSTSSLVSAEPLSSLTSRTKHTVVQRSRIYVPPNGATLYSVEDLSSSSQSSPKKQLLTVTSKAKVSSSAKNSTKSNPNIISIQLQDLTADTVYIGTISIGTPAQNYSVVFDTGSSDMWVPSQACNTTVCMSLLRYNSSASSTYRIENKSFEIKYGDGSQVSGLTALDRVLLSDVSVANQSFGMASVDDSTIAKKGIDGVVGLGFGRAANIKGYTTIVESMLARKIILQPIVSIWLGRQRMGGSSEGSGGAIIFGGVDTTKYVGTSLIVVPTKAASTLHQHIPGAIEEPQVGWILPCNTSAGDLNFTIASQQFRVPAEELVVLYRIPGYVDYCKSAVDVATSDSQTEWILGASFLKNLYTVYDYEALSIGFAQPSNIYNSLANVTLLPNLSSSPSGQGNGTNGTQGGDGGSAGGTNGPYNQNGSAQFLLGSHVVFFTCVATIVTTMLLASGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0X1</accession>
    <name>A0A9P6N0X1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Presequence translocated-associated motor subunit PAM17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">PAM17_2</name>
        <name evidence="13" type="ORF">BGZ80_003218</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Component of the PAM complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Mitochondrion inner membrane</location>
            <topology evidence="1 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the PAM17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000184">
        <property type="protein sequence ID" value="KAG0021013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0X1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001405">
        <property type="term" value="C:PAM complex, Tim23 associated import motor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013875">
        <property type="entry name" value="Pam17"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28021">
        <property type="entry name" value="PRESEQUENCE TRANSLOCATED-ASSOCIATED MOTOR SUBUNIT PAM17, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28021:SF1">
        <property type="entry name" value="PRESEQUENCE TRANSLOCATED-ASSOCIATED MOTOR SUBUNIT PAM17, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08566">
        <property type="entry name" value="Pam17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 12" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="6 12" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="9 12" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="88"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="121"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU367146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0021013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="220" mass="24428" checksum="F1EE38938F27E734" modified="2023-09-13" version="1">MAAATFTIRFISIQSHASSIGKGMLLSRSSAHLPVIRTSSCLSSGRTTPSFSSRRWTSTGTNATSENNTMDWSSYFLLRGTRRTYERVFMVPCGLLSLLGAGAYFAQKDFDPTPILGMDQVIVYGLGTVAAGIVGLAVGPVVGNMVFRVTHSKAKPLVDMMDKEFHKHIVKNRADPTANSVRNPVPDYYGEKIKSVSDYRKWLRKQREYRRKATFFVGDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0Y0</accession>
    <name>A0A9P6N0Y0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Smg-9, nonsense mediated mRNA decay factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">SMG9</name>
        <name evidence="2" type="ORF">BGZ80_004726</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000238">
        <property type="protein sequence ID" value="KAG0020136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0Y0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039177">
        <property type="entry name" value="SMG9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14270">
        <property type="entry name" value="NONSENSE-MEDIATED MRNA DECAY FACTOR SMG9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14270:SF0">
        <property type="entry name" value="NONSENSE-MEDIATED MRNA DECAY FACTOR SMG9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="104"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0020136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="386" mass="41900" checksum="E74B188E1A2A72F0" modified="2023-09-13" version="1">MMSVAGFQTSGIDMHITPERMILLDTEPIFCLSNLENALRNERITDGVPLDVWLDHQALTMATFLISVCNVVLVMTGERESGSDRIFKLLQRVEVFMKALSASSSNSSNAPIQGAGTSASSTGQSGLGQDGVQREGLGDWCADIVLISNKLFGSINMAGIYPRFEDCFNTVSSDAANSSNSVASSLRKKRLSALSVSAESLSSDAEVSQEKETTSVPTEQIQPQQQDILNDERKSAPYFNFVILPFDSIIASGTSSTTNPSTAGPVAAKPSALSSNSSLQSAMSNLSVTINRYDILGASLRRPYHDVFGTVVQDQERWGVWAKGLRNKILSLSMRPQGGPALGPRNRPGIVSEREWLRYASRSWDSIRKADFLAEYVRASKLSREG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1G9</accession>
    <name>A0A9P6N1G9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_001897</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000145">
        <property type="protein sequence ID" value="KAG0021686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1G9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005227">
        <property type="term" value="F:calcium-activated cation channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045122">
        <property type="entry name" value="Csc1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027815">
        <property type="entry name" value="CSC1/OSCA1-like_cyt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032880">
        <property type="entry name" value="CSC1/OSCA1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018">
        <property type="entry name" value="PROBABLE MEMBRANE PROTEIN DUF221-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018:SF5">
        <property type="entry name" value="RE44586P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14703">
        <property type="entry name" value="PHM7_cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13967">
        <property type="entry name" value="RSN1_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="137"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="201"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="600"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like N-terminal transmembrane" evidence="3">
        <location>
            <begin position="126"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like cytosolic" evidence="4">
        <location>
            <begin position="244"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="492"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="91"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="511"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0021686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="647" mass="70137" checksum="A9D08CF16D19760F" modified="2023-09-13" version="1">MKDDEAFRQQEEALASASISHSNSDGELISNLQPQASTRHTHNTASGFEGRIDSMGHPADIDYTQNKVNSNSVEESEDTKTGKTYPQNKDTSTASPTCSTSSYPNNQDRLQDSQPSGDISKPVRDILISKIGLDHYLLIRFLGMLTSLSVISAVLAIAVLVPVYNIGQSGEDMDTIGTNSLSRTPGVEALHIGNATNNERLFATVMVTAVVSALITLWTWTELMMFLKLRKDFLFRSSSRYSSKVVLLQHIPKDLQSVLALKQALSTAPGGGVEHVYLVRDVSTLEKAVKRRQVVLDMLEEVESRYMAAIARASALVSVTSLSMRSRSELGKGLDRLKACFGYGGVDIGLVGNQSEGDYVGPLKMYQLEGVPKISLTDLSTPGVASSCTLSGIKADSGVGTQTQHHSNLGGSSSSMLTALRWFQKPKRPTHYNGIPFLSKRQDSIRYYRGELCRLNKVISQEYEEQALAMAADQEYQGPGQRQAIARRHGITNTKGVPAQETGKNSAVLHSDTNSDSTPSGTTEKREIDLITSKSNGVKVLSSAFVLMKTRAGAKAVASGTIASDKLPSSARTMGIPPHDIEWRALGQSESGWSSFISQVMITVVGILLLVVSGLVVFAISSMSVHNGWERNYPSAGVESQKYKQSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1M9</accession>
    <name>A0A9P6N1M9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Chromatin-remodeling complex subunit ies6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">IES6</name>
        <name evidence="7" type="ORF">BGZ80_004078</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000212">
        <property type="protein sequence ID" value="KAG0020517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1M9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031011">
        <property type="term" value="C:Ino80 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029525">
        <property type="entry name" value="INO80C/Ies6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013272">
        <property type="entry name" value="Vps72/YL1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31200">
        <property type="entry name" value="INO80 COMPLEX SUBUNIT C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31200:SF1">
        <property type="entry name" value="INO80 COMPLEX SUBUNIT C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08265">
        <property type="entry name" value="YL1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00993">
        <property type="entry name" value="YL1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Vps72/YL1 C-terminal" evidence="6">
        <location>
            <begin position="83"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="15"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0020517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="134" mass="15040" checksum="3A141321CFBE85BD" modified="2023-09-13" version="1">MASSITASPSSSSSGTLDQPNQVGGITNMAHIHKPFKKPGWHASKKTKNLKQIITLEKAKEWKTSQPTYWNIEALPSMTPQKKYCDITGLEARYTDPKTRLRYHSTEVYQLIKNQPIGVVQQYLGLRNAAVVLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N218</accession>
    <name>A0A9P6N218_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">E3 ubiquitin protein ligase</fullName>
            <ecNumber evidence="15">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">BRE1_1</name>
        <name evidence="19" type="ORF">BGZ80_000650</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">E3 ubiquitin-protein ligase that mediates monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 15">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 15">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the BRE1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="15"/>
    <dbReference type="EMBL" id="JAAAID010000114">
        <property type="protein sequence ID" value="KAG0022253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N218"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033503">
        <property type="term" value="C:HULC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16499">
        <property type="entry name" value="RING-HC_Bre1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058643">
        <property type="entry name" value="BRE1-like_CC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013956">
        <property type="entry name" value="E3_ubiquit_lig_Bre1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23163:SF0">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE BRE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23163">
        <property type="entry name" value="RING FINGER PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08647">
        <property type="entry name" value="BRE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26095">
        <property type="entry name" value="CC_Bre1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13920">
        <property type="entry name" value="zf-C3HC4_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 15" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="11 15 16" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 15" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="9 15" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 14 15" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="18">
        <location>
            <begin position="841"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="47"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="804"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="98"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="266"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="368"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="446"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="47"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="65"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="804"/>
            <end position="820"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00059679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU365038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAG0022253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="893" mass="102544" checksum="7DD6F73857E0E3CA" modified="2023-09-13" version="1">MRMPLPSQFKISPSRDSSVAAFMDDRGNRKRRLNEDSGQHGQVVASAAAAANGSPAPFIPPANKRQFTGSGSSSPLNNTKEDTENMTAAEGVLLNFQKEAIWRQMQEYKREIARAQERIDQLEDKQADYDSQINSVDAYWNKLLEELRTLVSRSRISVQKDDMFLKDGSSFASLLCQGSDLQQENQDIRELTENATKPTVEASCERTKEIVLKLLRIIEAWTTQRGSFWTGYRESDTAIQESSVIQQLVAEYNNITRQFKKGQTDIDSLQAKCHEYSGQVLRLKNELEITKHRIEETSENLDDSSEKIRQIERRIDREKNALGSTISSSQSITNIANITAATLNDMSEASRDELLQFRRLAISRLAEIEETNLQKTQMKDDLDKLRAQLDQLSDEKIQDSQYVRTLLVQMQSARHEGEFYRGEVLRLRADLEDLHASRRRFVDTLETEEKNRRATLEAELKKLESDISRVKDIRDRFQQMYENRCSKDDYEIQQNQEIRKIANTRKDRITTLSTEISRLQTMLATTSDDWDSYAFYLKNPDDVATLKDLKSKLSESGELINKLHMELESTREASLQARDLEAVRSSESQLKEQVDALSTRLAHLDSIVGPEADDEIKALMTAIEARDAAIKRLELKVQAHEAVQTPLLNELHTVANAWGQLEEATSRKAIDLAQKEDLIFKLLSDKTRQESKCNNLIRAKDQSANMMAVMKRQSDMQLDQISRLEERERSLNQQMTTLEKEQTVLSSEVTAQKTKLQEYTQINSGYKEKFSRQEERLLELQSLLKERTDAFENETAVRKRLVGESESMKRKIEEHAKKSEGGSGDSEASKQAARYLKLLKCPACDVNFKSHVILRCMHVFCKNCMDKQMEFRQRKCPTCRENFGAKDVKEIYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N279</accession>
    <name>A0A9P6N279_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">leucine--tRNA ligase</fullName>
            <ecNumber evidence="3">6.1.1.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Leucyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">CDC60_1</name>
        <name evidence="14" type="ORF">BGZ80_003036</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>tRNA(Leu) + L-leucine + ATP = L-leucyl-tRNA(Leu) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:11688"/>
            <dbReference type="Rhea" id="RHEA-COMP:9613"/>
            <dbReference type="Rhea" id="RHEA-COMP:9622"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57427"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78494"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.4"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.4" evidence="3"/>
    <dbReference type="EMBL" id="JAAAID010000178">
        <property type="protein sequence ID" value="KAG0021102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N279"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004823">
        <property type="term" value="F:leucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006429">
        <property type="term" value="P:leucyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07959">
        <property type="entry name" value="Anticodon_Ia_Leu_AEc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00812">
        <property type="entry name" value="LeuRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.740.10:FF:000001">
        <property type="entry name" value="Leucine--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.740.10">
        <property type="entry name" value="Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004493">
        <property type="entry name" value="Leu-tRNA-synth_Ia_arc/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055416">
        <property type="entry name" value="RBD_LARS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00395">
        <property type="entry name" value="leuS_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45794:SF1">
        <property type="entry name" value="LEUCINE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45794">
        <property type="entry name" value="LEUCYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24810">
        <property type="entry name" value="RBD_LARS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="ValRS/IleRS/LeuRS editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 14" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class Ia" evidence="11">
        <location>
            <begin position="23"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="domain" description="Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding" evidence="12">
        <location>
            <begin position="635"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="domain" description="Leucine--tRNA ligase RagD-binding" evidence="13">
        <location>
            <begin position="785"/>
            <end position="857"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF24810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0021102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="923" mass="103880" checksum="8E5EFE06641FC837" modified="2023-09-13" version="1">MEQIGVPRGEIHKFADPLHWLSYFPPIATSDVKKIGYKIDFRRSFITTDANPYYDAFIRWQFNKLKALNKVKFGERYTIYSPKDGQPCMDHDRSSGEGVGPQDYTCIKLKVLEFSPEAQAVLAGNKDIEGKQIFMVAATLRPETMYGQTNCFVGVDLKYGVFKTNKADELFLITERAARNMAYQNLSPSTGEVVKVADFVGRQLIGTQVKAPLSSYPSVYVLPMDGVLATKGTGVVTSVPSDSPDDYATVMDLKKKPDYYKIKAEWIASYEPIPIINTPTYGNLAAPTICAQMKINSQKDKTQLALAKEAVYKDGFYNGVMVIGDYSGKPVQEAKPLIRQTLIDTNQAVPYNEPENLVMSRSGEECVVALMDQWYLDYGEPEWRKLAEECVEGMNLYTDETRNAFEKNLAWLNQWACARSYGLGTRLPWDHNFLVESLSDSTIYMAYYTIAALLQGGSIDGSVPGPLGIKHEQMTDQVFEYIFAEGPVPTDSNISKASLDKLRREFEYFYPFDIRNSGKELIPNHLTFAIYNHVALFPKKYWPRSIRANGHLTINGEKMAKSTGNFMGLAEAVDKYGADATRLALADAGDGGEDANFEDGTANAAILKLHTLTEWIQETLASKDQLRTGEFNFYDRVFESQMNKLINQAEADYEATFYREAVKNGFYELTAARDFYREACLLMDITMNKDLIMRYIEVQTLVISPIVTHWSEHVWGKLLGKEGLVVNARWPKSGPVDEAVLLEIDYLRRQVASVRATETQAIKKKKKGKADVFEPSKPKKITILIASKFPEWQENAIEVLKGSFQPDGKDGKFFDDDKVKKELAAKGLMKDKKVMPFVHDVKKKAEQHGASAFVQTLPFNELQILKDQSEYLRKVLGYETLNLIKSDEVVKATEGDADQEDYVRAAEQSVPGLPTFIVKNIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N364</accession>
    <name>A0A9P6N364_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Topoisomerase 1-associated factor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">TOF1</name>
        <name evidence="7" type="ORF">BGZ80_000485</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000110">
        <property type="protein sequence ID" value="KAG0022344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N364"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031298">
        <property type="term" value="C:replication fork protection complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000076">
        <property type="term" value="P:DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043111">
        <property type="term" value="P:replication fork arrest"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044998">
        <property type="entry name" value="Timeless"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006906">
        <property type="entry name" value="Timeless_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22940:SF4">
        <property type="entry name" value="PROTEIN TIMELESS HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22940">
        <property type="entry name" value="TIMEOUT/TIMELESS-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04821">
        <property type="entry name" value="TIMELESS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0236">DNA replication inhibitor</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Timeless N-terminal" evidence="6">
        <location>
            <begin position="32"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="515"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="864"/>
            <end position="891"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="953"/>
            <end position="1097"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="517"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="540"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="558"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="869"/>
            <end position="891"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1002"/>
            <end position="1011"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1016"/>
            <end position="1027"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1042"/>
            <end position="1054"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1067"/>
            <end position="1076"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1079"/>
            <end position="1089"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0022344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1097" mass="126920" checksum="AC45F0254A8B3C8C" modified="2023-09-13" version="1">MDPDTESLLVSTCLALGGYEDISEDMNDDRQVYVMGDECLGCLKDIKKFIKYYDEPGDNVALTFLGKLGILEKDLIPIMLLNSPPNNPVKERLVLACIEVIVPMTWIIDYKELQKLAVMEEDHSVVGNLHQRLEILRGYKRAFLKPGVLRTVFDVLLRPLEVEHRMRTTRDQAIIRLGLSLFRNLVAIPDTESPVSGTMDQFISSIMQEELLARFQDENIMALLITLASSASEPQLSEFNAMTLEIFYYIFTGIDADDLIPSVTDGTRLVLHKKGALFSSFETHLDSIKKPRAPVRRKKEADDYKKTVTKSGLGILRGLALTLLESCFNPLFGSMRGDIEMEREKIKGYHRSQYHCLMAFLLRFQRLYLDYVNRECNEQKKNATPEQQLLLEEEYRKNVLQCDFDLVAKALEVVSVYQVIGYMHRLNEEPYNGRVMTLHIMFKSPNETYRDASDIVQNNLYYQEATLEVFLELAKRYKLQSKLMIHILLKTLETYSNSKSYMSTLKRKRIIAKKRKEANAKSKDGQETTEERTADQNGIENGDGNQAQGEEQEQRQGDEDEEREDESALTMKEHQFVFKDYERRFATERIIDTYCVFLENFEDLDEAQLHWAASLFHRVAVNAGNIAIFYKLSTLHLFHRILQSGREETKRDMVPFVSYVIHQFFKKMQEYPLLVVEVLFPRSSKACLDINVGREEAEKELRIQETKKEKRMMATELEIDPNRSEEDQIKIVVTAFIYDDQTELVEWAVEILKGAVISRQLMTLRSEEELAENPDLMHSVENVEDIPVVADNPARNRGIRLVPRLRLLFKLLHFTREDHEMKFKIPKEIPTDTLSDYQDMIETILKEDPEHFSQYDYSQLIVTKKKPKRTDQRREGGGGRRKKEELKETHTAEYVIDSEDDDDDAYFESEKGLRERTHIDFTRAEERHRKMVIENEKNKSRTQKDMLVKKFGPQSVATEDEQDDTVQQNIKKPPLPKVVSDLDSDSEEEETRKPPPKSTSDVESDDDDSDDISLSRPTPRQQYSSQRKTVRLDDSSDDENNDGATQPLSFTQRMAQAGNKRRIILADSDEDEDAYDSDNQNGSQESNSGPAKKKFAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N395</accession>
    <name>A0A9P6N395_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">40S ribosomal protein S19</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RPS19_1</name>
        <name evidence="4" type="ORF">BGZ80_000998</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eS19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000122">
        <property type="protein sequence ID" value="KAG0022129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N395"/>
    <dbReference type="OrthoDB" id="428974at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000028">
        <property type="term" value="P:ribosomal small subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000118">
        <property type="entry name" value="40S ribosomal protein S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001266">
        <property type="entry name" value="Ribosomal_eS19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018277">
        <property type="entry name" value="Ribosomal_eS19_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11710">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11710:SF0">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01090">
        <property type="entry name" value="Ribosomal_S19e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01413">
        <property type="entry name" value="Ribosomal_S19e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00628">
        <property type="entry name" value="RIBOSOMAL_S19E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0022129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="146" mass="16052" checksum="6831AD61C7C8F9C0" modified="2023-09-13" version="1">MAALYSVTVKDINAHDFNRAYAAYLKRSGKLEIPKWVDLVKTGTNKELAPYDPDWFYVRAASVARHIYLRRSVGVGALKKLHGGTVNRGSRPSHHKVSSGSIARKVLQALEKINVLEADENGGRKITVDGQRDLDRIAASVAQAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4F8</accession>
    <name>A0A9P6N4F8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008898</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000005">
        <property type="protein sequence ID" value="KAG0024740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N4F8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38848">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 3 PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38848:SF3">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 3 PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="178"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0024740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="303" mass="33786" checksum="BC68D51E9C9A7E4A" modified="2023-09-13" version="1">MSTLFGRKTAGTKLGTINYARGLVIALYLVSWAFSFMATMLVQTNNFNIISCRMSIYTCIILYAISKIIIYLFLMEKVYVVTAVGSTRRDFTLYRVNMFLLSPYLAILGLMIRFENSSIQPNGECSIGLDKPASLPLIIYDIFLSCWLTALFIRPLMSSTSLLQGPTKGKLRDVARRTLMGCVIALILSSTNVFTLVYFNGHERGLICLASCTLDVTLNAITIHWVTSRGGGRIAGNVRQTSRDRRISNGFHGVHSGGYNYAPHEKQVAPLDSHLSITVESYVEEYHQLHCNGNPESSSSHHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4K4</accession>
    <name>A0A9P6N4K4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Small COPII coat GTPase SAR1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Small COPII coat GTPase sar1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="primary">SAR1_1</name>
        <name evidence="22" type="ORF">BGZ80_004017</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasmic vesicle</location>
            <location evidence="2">COPII-coated vesicle membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
            <orientation evidence="3">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 21">Belongs to the small GTPase superfamily. SAR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000021">
        <property type="protein sequence ID" value="KAG0024351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N4K4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012507">
        <property type="term" value="C:ER to Golgi transport vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00879">
        <property type="entry name" value="Sar1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000161">
        <property type="entry name" value="Small COPII coat GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006687">
        <property type="entry name" value="Small_GTPase_SAR1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45684">
        <property type="entry name" value="RE74312P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00328">
        <property type="entry name" value="SAR1GTPBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51422">
        <property type="entry name" value="SAR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="16" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="10 21" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="11 21" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="13 21" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="14 19" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="17" id="KW-0460">Magnesium</keyword>
    <keyword evidence="15" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 18" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12 21" id="KW-0653">Protein transport</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 21" id="KW-0813">Transport</keyword>
    <feature type="binding site" evidence="19">
        <location>
            <begin position="27"/>
            <end position="34"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <begin position="129"/>
            <end position="132"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00021124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR606687-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR606687-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="RuleBase" id="RU003926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAG0024351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="189" mass="21372" checksum="72A4B47DFA6C814E" modified="2023-09-13" version="1">MFIIDWFRDVLSSLGLFNKNAKILFLGLDNAGKTTLLHMLKNDRLATLQPTLHPTSEELSIANVKFTTFDLGGHQQARRIWKDYFAEVNGIVFLVDTQDHQRFLESKAELDALLAIQQLERVPFLILGNKIDAPGAVSEEELRSVLGLIQTTGKGKVPLKDMRPIEVFMCSVVMKQGYGDGFLWMSQYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4M8</accession>
    <name>A0A9P6N4M8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein-serine/threonine kinase</fullName>
            <ecNumber evidence="8">2.7.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_001334</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-seryl-[pyruvate dehydrogenase E1 alpha subunit] + ATP = O-phospho-L-seryl-[pyruvate dehydrogenase E1 alpha subunit] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23052"/>
            <dbReference type="Rhea" id="RHEA-COMP:13689"/>
            <dbReference type="Rhea" id="RHEA-COMP:13690"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the PDK/BCKDK protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.-" evidence="8"/>
    <dbReference type="EMBL" id="JAAAID010000013">
        <property type="protein sequence ID" value="KAG0024577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N4M8"/>
    <dbReference type="OrthoDB" id="241648at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004740">
        <property type="term" value="F:pyruvate dehydrogenase (acetyl-transferring) kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010906">
        <property type="term" value="P:regulation of glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16929">
        <property type="entry name" value="HATPase_PDK-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.20">
        <property type="entry name" value="Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036784">
        <property type="entry name" value="AK/P_DHK_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018955">
        <property type="entry name" value="BCDHK/PDK_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039028">
        <property type="entry name" value="BCKD/PDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11947:SF3">
        <property type="entry name" value="[PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING)] KINASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11947">
        <property type="entry name" value="PYRUVATE DEHYDROGENASE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10436">
        <property type="entry name" value="BCDHK_Adom3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69012">
        <property type="entry name" value="alpha-ketoacid dehydrogenase kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="9">
        <location>
            <begin position="286"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0024577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="422" mass="47892" checksum="1294753990F9BACC" modified="2023-09-13" version="1">MYRISPQLSEKIKHFATFPQTGVSLRQMVMFGQNPTQGTLFKASQFLSEELPIRLAHRVKELEELPHNLSDMPSIIRVKNWYAQSFQDIVEFPNKEMTSGLKEMAKSMNRQADMQALPGNSPNLAVPNGSNSNGRRGVSLSHRYHSAMDGVEWPAEMHSYNEKFTRMIEAVKRRHDPVVTTVAQGILEFKQSKPSYIVDTDVQAFLDRFYMSRIGIRMLIGQHIALNKGPSRKDYVGIICTRTNLADMAQEAIDNAKFICEDYYGLFRGPEVHLHCKKDLEFMYVPSHLSHMLFELLKNSLRAVVEQYGTECDEYPPIKLIVALGKEDITIKVSDEGGGIPRSGVPLVWTYMYTTAPSQHLDPTFDKSDFKAPMAGFGYGLPISRLYARYFGGDLKLISMEGYGTDVYLHLNRISNSDEPLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N5K9</accession>
    <name>A0A9P6N5K9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">LSM complex subunit LSM5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10 12" type="primary">LSM5</name>
        <name evidence="12" type="ORF">BGZ80_004772</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">LSm subunits form a heteromer with a doughnut shape.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000024">
        <property type="protein sequence ID" value="KAG0024258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N5K9"/>
    <dbReference type="OrthoDB" id="429711at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990726">
        <property type="term" value="C:Lsm1-7-Pat1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005688">
        <property type="term" value="C:U6 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01732">
        <property type="entry name" value="LSm5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000003">
        <property type="entry name" value="U6 snRNA-associated Sm-like protein LSm5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033871">
        <property type="entry name" value="LSm5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20971">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20971:SF0">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0007">Acetylation</keyword>
    <keyword evidence="3 10" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7 10" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 10" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="11">
        <location>
            <begin position="21"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0024258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="98" mass="10659" checksum="B28440D3DB1AE99B" modified="2023-09-13" version="1">MSAPNSSGSAAAPAVASIHQLPLELIDSCIGSKIWVVMKSEKEFTGTLKYFDDYVNMVLEDVTEYENTPEGRKTIKLEQILLNGNNICMLIPGGEGPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-10-08" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N7B1</accession>
    <name>A0A9P6N7B1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Arm-like repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_007713</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000004">
        <property type="protein sequence ID" value="KAG0024778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.80">
        <property type="entry name" value="E3 ubiquitin-protein ligase SopA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056251">
        <property type="entry name" value="Arm_rpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879:SF9">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23948">
        <property type="entry name" value="ARM_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="16"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141571">
        <property type="entry name" value="Pentapeptide repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Arm-like repeat" evidence="4">
        <location>
            <begin position="216"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1196"/>
            <end position="1237"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1238"/>
            <end position="1279"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1280"/>
            <end position="1321"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1322"/>
            <end position="1363"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1364"/>
            <end position="1405"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1406"/>
            <end position="1448"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1449"/>
            <end position="1490"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1497"/>
            <end position="1531"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1535"/>
            <end position="1572"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1573"/>
            <end position="1614"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1615"/>
            <end position="1656"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1657"/>
            <end position="1698"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1699"/>
            <end position="1740"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1741"/>
            <end position="1782"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF23948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0024778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1872" mass="208694" checksum="969290B4A9BB9C9C" modified="2023-09-13" version="1">MVWSPFSSPSSRLPLEDVLEIVKKYLDNARKESNPTKAYKLCKDAKSQIKIAEKIFAAKNAKGLATNDGIATAYYEHGDLLESLGYHEKAQKSHRKAVKWGYIDMLTHQVESIFLSLFTPDDLPTASSVTAARPQGNSQPNTVQLTRQSHQETTTKVKNGPSTLNDQEVASAVAKYALPKVGERIANTPQLAYCLSLLHPSLMSKEGLGNIGYDWLQANVNDPNEKKRLQTMATDVVRAFVRDELKKPNVVAEVVSLAAVLNQEDFRKLLQTFVDGIDKSVLLEVHLLDGLAQLIRNAEQDYIDADDLVKILGLLNTRLKSTHKQSTRHIHRLALTMSNVLDSMVDSQVEGIGYEQLHEPLSEYLKELQESSDPYLVYQAAYAYQALQYVPDDETILQTALRRTGRVVQGISGVVSAVKALDLNMFLEGLKSIQGGLAGAGDAIVLVKDAYSKTLTESSFLENLKENLSCPRKSVWYPALRGLDMLLQENRFTEFRQLFQDVPCKQDPAFQWGVCQRLGEVVANTFLQAETRQCALSFLGELYKDDTIWGRANIKQWILRILIQMASLPKGSIANQARELLQELKTNGSAEKRLLYQSCGKDRAGSGLIIVTLPPQESPLLDRVQGKPDVEIPLRQLKRERLKDQGGDVYISPRAKSGLRATDDFDLTSKVQEFLDSDKKVFLILGDSGAGKSTFNRTLEIKLWDKYGKTDRRIPLFIHLPTVKEPERDMIAERLRKANFTEKQIWELKNQYEFILICDGYDEKYNGADYRDCFQPNDRNNNGRPELFQEAVITPFNKSQIQDYIDQYVSLRNPEWASMDYQEAFKQIPNLQDLVKNPFLLKLAMDVLPRLLNTSSNFSAARITRVGLYDEFLAQWIERAKIRLRELDLSSRDKETFMELSGSGFKQNSIEYLKELVTAIYDNQNGNPVVIYLERRDRKTWKEALFNKEDGRHLLREAIPLSRNGDMYRFIHKSVLEYGLALAVFDPSGHEESLEPTSVTSRRMSTNSALSFEISTSMEKTTIATEQPLLDSPLGRKNLVGEASIIQFLTERVRQQPGFKDQLLAVIERSKTDKMARTAAANAITILVRAGIQFNGADLRGIQVPGADLSFGVFDSSQLEGADLRKANLRNIWLRRANLSGAQMTGVQFGELPFLQEDSEVTCSVYSPNGRLLAVALEGGYLHLYETASWNRIWSLGSHSSGAEQVAFSPTSHQIALKDDGKAVLLWDIDTRNCTHALQGHTHGITAIKYSPKGNRVATGSFDKTVRLWDVETGDCVHILQGHSDGIWSIVYSPDGNQVASGGDDSTLRLWSTDTGDCIHVLRGHTNKVWSIAYSPKGDRIASASFDSTVRLWDVDTGRCIYNLVDHKRMALCVAYSPRGDQIASGGMDFTVRLWDVVTGNCIHILPGHGGGVTNAIYSPKGDQIASSGRFDKTVRIWNVETGDPVYVLQGHNFKINSIAYSPNGNQVASGCNDKTVRLWDVNDSEYAHTIHGRLDVSSVVHSPNGGQVASTSLDHKVRLWDVENGDCLHTLHFNDSVYSIKYSPKGDQIASGSFDKTVTLWDVNTGDCINTLQGHDNAIMSIAYSPKGDRIVSGSYDKSVRLWDVATGNCLHNLQGHDEQVSIVVYSPKGNQIASGSQDKTLRLWDVDAGDCVRILRGHSNWVTIAVYSSKGNQIASGGYDKTVKLWDVDTGDCIRTMQGHNGHITGIMYSPKGNQIVSGSKDYTIRQWDIETGECVHILQAHTSEVTSVMYSRDGNLIASGSNDRTARLWDASNGECVVTISDFKENVSSVSLETTFNGQYLVTGSIDKSMRRWQIIKEGPEHKALLCWSSLHEVLTVSGATFKDVRGLTQPNQKLLSQRGANISISPSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SS28</accession>
    <name>A0A9P6SS28_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Oxidoreductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_007384</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003768">
        <property type="protein sequence ID" value="KAF9995933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SS28"/>
    <dbReference type="OrthoDB" id="1933717at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760:SF37">
        <property type="entry name" value="CLAVALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9995933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="290" mass="31588" checksum="C098AB32E3BBFE93" modified="2023-09-13" version="1">MPPHPDPTAKNFTSTLHTDTYPAIAHSNHQARTVLITGASKGIGRATAISFARSGAANIVIAARSGLDEVEKELHAAAPSSSSPPRIIKIQLDVVSEASVADAAERVKQECGYLDILVNNAGYLEDRVPIAESNPSEWWKTWGVNLKGVYLMTRAFLPLLLQGKVKTIINVSSGGAHFTTRGASAYQTTKFALLRFTEFIAVEYVDQGIISIAMNPGAVPTELALNLPKGVHQFLVDTPELAADSVTWLTQHRLPWLSGRYVSVNWDLPQLLAKKEEIIEGDKLKMRIVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SSQ2</accession>
    <name>A0A9P6SSQ2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006810</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003385">
        <property type="protein sequence ID" value="KAF9998320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SSQ2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9998320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="73" mass="8343" checksum="3CD114AE7EC21236" modified="2023-09-13" version="1" fragment="single">KTAQDKADFGRMMKAAALSRIELAIRIQDELCRRESEKVPASYPTRVELNNALRRIQSTTPTPEKPKKRKSES</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SSS9</accession>
    <name>A0A9P6SSS9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Zinc finger domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ZFAND3</name>
        <name evidence="6" type="ORF">BGZ80_006758</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003351">
        <property type="protein sequence ID" value="KAF9998563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SSS9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1110.10">
        <property type="entry name" value="AN1-like Zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035896">
        <property type="entry name" value="AN1-like_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050652">
        <property type="entry name" value="AN1_A20_ZnFinger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000058">
        <property type="entry name" value="Znf_AN1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10634">
        <property type="entry name" value="AN1-TYPE ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10634:SF67">
        <property type="entry name" value="AN1-TYPE ZINC FINGER PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00154">
        <property type="entry name" value="ZnF_AN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118310">
        <property type="entry name" value="AN1-like Zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="AN1-type" evidence="5">
        <location>
            <begin position="119"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="57"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="57"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9998563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="188" mass="19753" checksum="4D45EE401BCAC3AA" modified="2023-09-13" version="1" fragment="single">NPINNNLCSKCFKELSQKNGTLQVENNTAAVSSAATTTTTPSEKSTTATTLVVPAPSSSSAIPIASPAPSTPAFSAPVAAQASTPAPDSGASTPTSIASDAQEGLAPGERPPQVNKGRCYLCRAKIPLAKQAINKCRCEFVFCDTHKATTKHDCDFDFAKMGKDLLTKNNPKLNDKPRGGRSFTRIQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6STH3</accession>
    <name>A0A9P6STH3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HIT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006274</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003094">
        <property type="protein sequence ID" value="KAG0000873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6STH3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033699">
        <property type="term" value="F:DNA 5'-adenosine monophosphate hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990165">
        <property type="term" value="F:single-strand break-containing DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000012">
        <property type="term" value="P:single strand break repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12486:SF4">
        <property type="entry name" value="APRATAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12486">
        <property type="entry name" value="APRATAXIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11969">
        <property type="entry name" value="DcpS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0000873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="230" mass="25585" checksum="1E33964BEF3EF388" modified="2023-09-13" version="1" fragment="single">MTNRGKLIDTEDLIRHKDGRIDLFNTILARKDTDAQIPVLSDTKSHHGTTSSHPYHRPEPTSQGGGPSLTKRHHTETSTSTGGPVKGSWDGTAGSIKAPDSTKNDSSLSERKKLPSVPTMGTAVTAKTNKITGGKQLSFQMIFISYVNDPSSVPKDIQYWHDENHLIIRDAYPKAKVHMLVLPRQRIDKVTKLSGPSGIKIVEDLMNRANWLLERLKKESPNLEFKMGFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6STN3</accession>
    <name>A0A9P6STN3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">D-3-phosphoglycerate dehydrogenase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">SER33</name>
        <name evidence="6" type="ORF">BGZ80_006042</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002988">
        <property type="protein sequence ID" value="KAG0001977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6STN3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000025">
        <property type="entry name" value="D-3-phosphoglycerate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050418">
        <property type="entry name" value="D-iso_2-hydroxyacid_DH_PdxB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43761:SF1">
        <property type="entry name" value="D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE CATALYTIC DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43761">
        <property type="entry name" value="D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_1G13630)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase catalytic" evidence="5">
        <location>
            <begin position="67"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0001977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="173" mass="18444" checksum="0E4199CCD80808CE" modified="2023-09-13" version="1" fragment="single">MSSPPANHPLSTSTPSTTRVMPTSTNSTTAGADTPTVEIRGRERQGSFGGSTKAKVLKPFNTANIKILLLENVNETAVSALRGQGYQVETHAKALAEDVLIEKIRDVHCIGIRSKTKLTKKILDAAEKLGVIGCFCIGTNQVDLEHATQKGIAVFNSPFSNSRSVAELVLAEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SUG0</accession>
    <name>A0A9P6SUG0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_005577</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002748">
        <property type="protein sequence ID" value="KAG0004656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SUG0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0004656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="209" mass="24500" checksum="61D13C56978F3F16" modified="2023-09-13" version="1" fragment="single">YLNNRDVTQVHWESFFVHYKYSSSEKQAAMSKYRQMIKEMEPNDEAIKKGLLQQFNEDKSKMNSYWSELEEKENNFLISLHVLTYYYWNEYREITPEKQSRKSQRTKLEEKDLLVAMSGIINSRMEGSNEIFGEDIVNSINKSCLLPQAHMPSVELELILEPLRIAFKAGGESGLLDQIEEFIGDDARARKAKNETSQLRAQVLDIIRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SVY6</accession>
    <name>A0A9P6SVY6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_004639</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002344">
        <property type="protein sequence ID" value="KAG0007456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SVY6"/>
    <dbReference type="OrthoDB" id="2373574at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0007456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="255" mass="29594" checksum="627E132118C3F010" modified="2023-09-13" version="1">MGNKHDYNNEMLREFIKRVSRVICLDADLTNDDVQLVKSLRNDVRVIHNTFKLQEGDQVVMYEKKSLLTLKVIELLKEGKRIWISSTLSAERTETLHRQLQQEGFRGECITSNTVDDIKKHAAENINKAIADLDYFIHTPTISVGIDCNLEYFDYVAGFFSTQSQVTVESCRQMMRRIRHVKSKTYLVYVDRATNNLPTTVEDIDNWINEQGHILMGDKKVEGLRVRLGYGGRFSLPTCFYSQLWCQRFISEVLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SW93</accession>
    <name>A0A9P6SW93_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Inorganic phosphate transporter pho84</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">PHO84_3</name>
        <name evidence="8" type="ORF">BGZ80_003828</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002032">
        <property type="protein sequence ID" value="KAG0008127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SW93"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24064">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 22 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="104"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="165"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="239"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="1"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="5"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0008127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="284" mass="31159" checksum="F52B8EE250B85EE6" modified="2023-09-13" version="1" fragment="single">TPRYVLDIENNLNKAEREVATVLENRNHLQSDDDNEVAHGPATAKGSFSDFCSYFSTWQNFKVLFGASLAWFSLDVAFYGVGLNNSFILSSINFGSVKGSTYATNWNAAVGQIIIVLLGSVPGYWATVFTVERLGRIKIQLIGFFMSCVLFAVLGFAYDEIRNKSTVLFIILFALTQFFQNFGPNATTFIIPGEVFPTRYRSTGHGIAAGSGKLGAIIAQVGFAQLKDHGGSNKGIPDLLKIFALFMLIGLLVTFLIPETKGKTLEELSNEGDFAISNEMEEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWA1</accession>
    <name>A0A9P6SWA1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Exosome nuclease subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">RRP6</name>
        <name evidence="11" type="ORF">BGZ80_003805</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the exosome component 10/RRP6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002023">
        <property type="protein sequence ID" value="KAG0008149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWA1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003727">
        <property type="term" value="F:single-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000467">
        <property type="term" value="P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071044">
        <property type="term" value="P:histone mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071040">
        <property type="term" value="P:nuclear polyadenylation-dependent antisense transcript catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071039">
        <property type="term" value="P:nuclear polyadenylation-dependent CUT catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071035">
        <property type="term" value="P:nuclear polyadenylation-dependent rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071036">
        <property type="term" value="P:nuclear polyadenylation-dependent snoRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071037">
        <property type="term" value="P:nuclear polyadenylation-dependent snRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071051">
        <property type="term" value="P:poly(A)-dependent snoRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071038">
        <property type="term" value="P:TRAMP-dependent tRNA surveillance pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06147">
        <property type="entry name" value="Rrp6p_like_exo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000059">
        <property type="entry name" value="Exosome complex exonuclease Rrp6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.80:FF:000001">
        <property type="entry name" value="Putative exosome component 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.80">
        <property type="entry name" value="HRDC domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002562">
        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012588">
        <property type="entry name" value="Exosome-assoc_fac_Rrp6_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010997">
        <property type="entry name" value="HRDC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002121">
        <property type="entry name" value="HRDC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044876">
        <property type="entry name" value="HRDC_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045092">
        <property type="entry name" value="Rrp6-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049559">
        <property type="entry name" value="Rrp6p-like_exo"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12124:SF47">
        <property type="entry name" value="EXOSOME COMPONENT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12124">
        <property type="entry name" value="POLYMYOSITIS/SCLERODERMA AUTOANTIGEN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01612">
        <property type="entry name" value="DNA_pol_A_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00570">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08066">
        <property type="entry name" value="PMC2NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00474">
        <property type="entry name" value="35EXOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00341">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47819">
        <property type="entry name" value="HRDC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50967">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="5" id="KW-0271">Exosome</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="HRDC" evidence="10">
        <location>
            <begin position="450"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="720"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="720"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="765"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="858"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00043957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0008149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="858" mass="95467" checksum="3633B6632EB634E6" modified="2023-09-13" version="1" fragment="single">MATHNIVADFEAWQTALFATLVRATKAANAIPANDVSFYRTLDRSFAANMDDVSTTTIDLCNGLLRQAGGPENEELNDSDDVNDRFDIITDVVDNMIEKVDVTIDEMKAPRKKGAAVVPQSAPVVALAKSNKLEYKLIHAQNIARPQLRFPDPVDNSSAPFIRKIKYKPNAKVDLNYQMDGASTDASSSDQIIQPHPYEYEIKNLEYPEHMFEQSPEQLYLPFDTTSAIWVDTEEALVDMCRTLEMQREIAIDLEHHNYRSYQGFVCLMQISTRDQDYVIDTLELRGSLHLLNQSFTDPKIVKVLHGAESDIIWLQRDFGVYIVNMFDTYHASKLLEFGSHSLAHLLKLYADYDADKRYQLADWRIRPLPKEMLSYARSDTHFLLYIYDRMRNALLDKSNPTTHNLLHATLLRSSETCLKRHEKEVYDAESGDGPNGWRNMYSKWNRALNNMQFAVFKALHAWRDQTARDEDESIRYVLPNHMLFTLAEKMPEEAAKVLGCCNPVPPPVKMNASDIAMLISRTKASVAPVLGGFKPVAIDVPVHVRFDPKTGLQGTQEIKKVEESSMASISSTPLEKAAQAQGGKVVAAASSGMFGKGKVQITDVTKPLANPTSLLATQSSLFGDRGKFNFSAAEEEGKELAKRIMLQLSAKPTESTPVFKEITNVVATTELVNDVVVEEKEKKVEEENEILFTPQEERVTKQKRTDVLVLSSMNKKRARAIDEDRAELANESGPSVGSSDVEDGENTEVVSVKKKKKAKKDKSLSGASSASGTPASSAPGSGDETPDAFKPFDYNSVRSVVDENVEDLTSGKRKKKKKGGANASGAESPAPFDPYSQLVEGAELKKKDATFSRNPKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SX54</accession>
    <name>A0A9P6SX54_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_002384</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001587">
        <property type="protein sequence ID" value="KAG0009437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SX54"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0009437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="170" mass="18535" checksum="EFE139978C68B42E" modified="2023-09-13" version="1" fragment="single">MISRLLAEAPIVGKASYTRTGLQYTRTQLPRPLSTAAILRTAPRPAFLSTTTPSTALKQDATGTHQRFYNSNGTSRMRLLSLTSGSRLVSRAFSTANTHHPRQIASSGPFTIPRRQSALQFYRTRRGNLIARRGIAVSAAPRILLHALRLPMGALTASLAGLSYAQYKVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXX6</accession>
    <name>A0A9P6SXX6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_001195</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001269">
        <property type="protein sequence ID" value="KAG0010767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXX6"/>
    <dbReference type="OrthoDB" id="2413106at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040481983" evidence="3">
        <location>
            <begin position="41"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="187"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0010767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="384" mass="40553" checksum="CDD4519306D3E89B" modified="2023-09-13" version="1">MRFSATSSPPTHPSSRSPSRKLKTLTLLLSFVATLSLVSAQKQTILLTFQDDNGAAIDNPLTIPLSECIPFNTTTLLPDTEGSYASAVASDTQAALNLYSGPYCQILQTGAVGMWNNTDATAGIASIRWEGSSTDLPGTLNPAGFPLINPPKSNETGSETGSDTKHNGTKTSNSDDTFIMDPSKGRVLVGLVSAILAVGIIIGVYLVYEAAQYIPPPKKPKKTAGEGGGIVGAKKVKKGQAYYKKPPKEDFGAGIGGSASAVENNRSNSMLLAPTSMQERPRHDRSSFASVASATVPTFVPRIPPRPTSTFTPNDSVLINILQDPVPSSNNNNTWASDLIQFGNDTPPYNTTPSTSGRAGEVLVPMHLLDGQQSPTRRIPGRPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SY08</accession>
    <name>A0A9P6SY08_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_001043</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001230">
        <property type="protein sequence ID" value="KAG0010977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SY08"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="867"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="242"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="328"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="487"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="745"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="750"/>
            <end position="762"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0010977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="891" mass="99237" checksum="15181E2EE57C938F" modified="2023-09-13" version="1">MSIQPSAKSILNSLVHRFGGTISDQLYSENFANSGSLPNNLHNPRSIPTATTNGISSSFSTTFQDSAVSARRSIGFNPVQDDTVYRRRTLSMGASSSNSSGASMSRSWSLTEAIHSANFWRRDEKLKQSDSAFDDFESSTESDERRDDFDSSVHLALPFQLLLVSSRFADAAVQSLWRNLVFHGQDAYQMQSLLSALSMDDGTPLVSLDNEPGCSMSGLEKLGEANEEEDEDGEVKEYRLMDRASDTSRSRHTVEDAKTGPAAKFNVYSPKYGSSEHPSPPPLRINENRETNMGWFDSWNNSLKQFSRFQGVAGVYGSNTETVTTPTATSAATTAGPSYIKGQRRHTSAGSGPKYRNGYPWLSSTDNERSRPNQSGPSVIKLDKSRWSYRVHVRRVILNFSHPQASPQMFRKVLECLRARCPDQIVALDLHANEKMRDSGLDNSEELERYFGSGFSKLRYLRLQGGFVDNQLLCALIKGLGSPERAPTEESSVDYTGYHYPPARSQRPTSMHSIYSAPPCRLSQVFLGPGSVTDSAVEKLIVAAGHCLEVFTVTSCVDVGGGALANLLTKCPKLRVLGVHRSLARDKDLLEGLGIEVDNATSNTHQVNEQPVTGNIENTNAGNCPPVQSARVRKIIVAPLQRLELGTVKLTRVGITEILKGTCETLRFLVLETQHFSEELLTDVITPFCSKLEGLYFDDPEYLQKQQQQMQGLGFSAGRRGAHLPNRHFEFGRSKRTFYSDPSHLYQHVPQQPSGQRRQQNQFSRAESKERQGAMRSQAPKISAWLGETRSAASAGFYAINSNLFVNEYEDVLARLQVTRAAIENVIQTLRSLTAFTVMQVDFIEESQGQSELKMMMREDEAWVQSAGFRALQLFYLFLFLSMIYFGTLRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SY64</accession>
    <name>A0A9P6SY64_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Grainyhead-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">GRHL1_2</name>
        <name evidence="3" type="ORF">BGZ80_001061</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001235">
        <property type="protein sequence ID" value="KAG0010952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SY64"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007604">
        <property type="entry name" value="CP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040167">
        <property type="entry name" value="TF_CP2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11037:SF20">
        <property type="entry name" value="PROTEIN GRAINYHEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11037">
        <property type="entry name" value="TRANSCRIPTION FACTOR CP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04516">
        <property type="entry name" value="CP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51968">
        <property type="entry name" value="GRH_CP2_DB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Grh/CP2 DB" evidence="2">
        <location>
            <begin position="1"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0010952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="411" mass="44874" checksum="151968D77798BDB7" modified="2023-09-13" version="1" fragment="single">MQRQDETPMTYLNKGQYYNVGLKDIEDYDGEVTSVIKVTFHEPSHRRLAARYWSFWLSQQPNPKTARALDIEKASSAGMLEVQSKTFDRISFKWNGKTGAKLMVRFNCLSTDFSRIKGVKGIPLRVHVDTYLEGIGDNNKDGRGERVPMERAFAKIKLFRDKGAERKNKDDHKQLEKMWDKMRGKNADTNPLVSILAPVQSTMIFSECLDHEETGEDETLDLSDTLTNDMAIEEGGGSPSYDVNEGEEVNGGGSHNDSRSSSRLDSEGALGSPSSVGGGGGGEDLGPVAPTSKKRRRITEAGGSPASPGTNINSSNGGLYSPHQSHVSAVPSISSPNAHVTAGADSGLPVTSTGQIMGRDENYVPLLPILSEKLEIQSSTISCVFRKTLKKELLVRVDDAMVAQMTDELDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYN3</accession>
    <name>A0A9P6SYN3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Carbamoyl phosphate synthase arginine-specific small chain</fullName>
            <ecNumber evidence="3">6.3.5.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Arginine-specific carbamoyl phosphate synthetase, glutamine chain</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">CPA1</name>
        <name evidence="14" type="ORF">BGZ80_000165</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-glutamine + H2O = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>hydrogencarbonate + L-glutamine + 2 ATP + H2O = carbamoyl phosphate + L-glutamate + 2 ADP + phosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:18633"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-arginine biosynthesis; carbamoyl phosphate from bicarbonate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Heterodimer composed of 2 chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CarA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.5" evidence="3"/>
    <dbReference type="EMBL" id="JAAAID010001029">
        <property type="protein sequence ID" value="KAG0012150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYN3"/>
    <dbReference type="OrthoDB" id="434at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004088">
        <property type="term" value="F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01744">
        <property type="entry name" value="GATase1_CPSase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.30.20:FF:000003">
        <property type="entry name" value="Carbamoyl-phosphate synthase arginine-specific small chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.20">
        <property type="entry name" value="Carbamoyl-phosphate synthase small subunit, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01209">
        <property type="entry name" value="CPSase_S_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050472">
        <property type="entry name" value="Anth_synth/Amidotransfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006274">
        <property type="entry name" value="CarbamoylP_synth_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002474">
        <property type="entry name" value="CarbamoylP_synth_ssu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036480">
        <property type="entry name" value="CarbP_synth_ssu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035686">
        <property type="entry name" value="CPSase_GATase1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01368">
        <property type="entry name" value="CPSaseIIsmall"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009475">
        <property type="entry name" value="PRK12838.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43418:SF7">
        <property type="entry name" value="CARBAMOYL-PHOSPHATE SYNTHASE SMALL CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43418">
        <property type="entry name" value="MULTIFUNCTIONAL TRYPTOPHAN BIOSYNTHESIS PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00988">
        <property type="entry name" value="CPSase_sm_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00097">
        <property type="entry name" value="ANTSNTHASEII"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00099">
        <property type="entry name" value="CPSGATASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00096">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01097">
        <property type="entry name" value="CPSase_sm_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52021">
        <property type="entry name" value="Carbamoyl phosphate synthetase, small subunit N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carbamoyl-phosphate synthase small subunit N-terminal" evidence="13">
        <location>
            <begin position="76"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM01097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0012150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="473" mass="51301" checksum="1D1DEF74BF1D99C9" modified="2023-09-13" version="1">MSAFRQATATTLTRAMALSAVARPMISRAAFKAAAPQRCLATVADTVFPANKAAPKPVQVQHSTPYQFDSAAPKAVPAALKLKSGHVFTGTSFGAQNSTFGEAVFTTSLVGYPESMTDPSYKGQILVFTQPLIGNYGVPGQVKDEFGLLKYFESNKIQCQGIVVNDYATKYSHWTAVESLGEWCAREGIPAISGVDTRAIVHLLRDQGSTLAKLEVGDEVLENKEVVEFPNPNTRNLVAEASTKEVYELNPMGDVKIALIDCGVKENILRCLVARGAAVTVFPWNYDFNKVLDQYDGLFISNGPGDPRAAMPTVQNLATAFKNPAPKPIFGICMGNQLMGMAAGLDVYKLQFGNRGHNQPAINMQNGRCSITSQNHGYALVDSVLAPGKTMNGWEKYFVNANDGSNEGIRHTTKPFSSVQFHPEAKGGPQDTEYLFDDFLKLARAEKVKSSNKPFFVTEPLSKDVTKPIEVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYQ0</accession>
    <name>A0A9P6SYQ0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Chitin synthase activator</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_000449</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001094">
        <property type="protein sequence ID" value="KAG0011747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYQ0"/>
    <dbReference type="OrthoDB" id="272077at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="30"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="30"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="57"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0011747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="683" mass="75715" checksum="35BD3A117618E079" modified="2023-09-13" version="1">MVGPLTMSASHILHRGRSVFSKLNKKYRLPSTSSSSADGAPASSSSSVRSFSTTPSCDSLLSSATSIDNTSNKNPVTTPQDPQDVARAQRHFDLAQQLLFGRHDHTKDETAAVEYYRIAMQLGHLEAQGALAFCYEFGLGIQADFVESERLYILAAEKGNGLAMSRLAFLRKYGRPSVKIDRIESEYWQQKINQQGPSALAWLMEAASVDGHDCCQYALGVCYHDGVGVEKNAIEAFYWYQKSAEQGNARGQGILGYCYGEGFGVERDRQKAMHWYRIAAEQGESVALYNIGYCYEDGLGVERNAFEAVKWYRRSAELGNAFAQNSLGYCYEDGVGIEQNLELAAEWYTKSAEQGYPWAECNLGYCNQNGIGVPKDDAKGAYWYRKAALQGHARAQHNLGFCYQNGIGVPKDPVEAVKWYMKSAERGNIFAFHSLGYCYQNGIGVQQNLDEAVYWYYLSAEENHAPAQLSLGYCFRNGVGVPKEPKEAVKWFYRSAIQGNALAQNSLGFCYEEGLGVEKNREKAVFWYEKSAAQNNPWAQCNLGFCYANEIGVAQNYEMAVKYYSLAAAQNHARAQDKLGVCLQLGQGITQDVKLAVRYFRLAAEQGHLAGQYHLANALEKGLGCDVDLEEASMWFERAAANGCRTSHERLQRLLARACLENGLESNYNGLFLGAIGHCAPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZA9</accession>
    <name>A0A9P6SZA9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_000073</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001008">
        <property type="protein sequence ID" value="KAG0012281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZA9"/>
    <dbReference type="OrthoDB" id="1914839at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd24142">
        <property type="entry name" value="ACL4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="254"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="259"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0012281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="279" mass="31109" checksum="CB1E812EC4ED7095" modified="2023-09-13" version="1" fragment="single">HFLECVEIQPNSGYSKFMYLGQLSEQLESISYFQQGVKLMMEERAAMPIDLTRGSAYLALSNKISSALCSMADIYLTDCCFEANAESQCEAYMIQAMQIEPVTPEVYQTLASIRLSQQRVDEAKAALAQGLALWLGSDPTDEDGPTPAYETRIALVKLLLEVAMIDEAFTVLNGLLEENDQVPDTLYLFGYANLIAADDVDPSSPSAEDEKKEQFENAREALNTCVKLWHATESTDEPMLQHCQELLETITQTIGPEVEQAEPEGGEIEYEDDEDEEMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZD8</accession>
    <name>A0A9P6SZD8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_011103</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000851">
        <property type="protein sequence ID" value="KAG0013404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZD8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043332">
        <property type="term" value="C:mating projection tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031097">
        <property type="term" value="C:medial cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990528">
        <property type="term" value="C:Rvs161p-Rvs167p complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051666">
        <property type="term" value="P:actin cortical patch localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097320">
        <property type="term" value="P:plasma membrane tubulation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000100">
        <property type="entry name" value="SH3 domain-containing YSC84-like protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046982">
        <property type="entry name" value="BIN3/RVS161-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007461">
        <property type="entry name" value="Ysc84_actin-binding"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47174">
        <property type="entry name" value="BRIDGING INTEGRATOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47174:SF2">
        <property type="entry name" value="SH3 DOMAIN SIGNALLING PROTEIN (AFU_ORTHOLOGUE AFUA_5G07670)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04366">
        <property type="entry name" value="Ysc84"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01887">
        <property type="entry name" value="SPECTRNALPHA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="161"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="36"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="43"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="68"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="82"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="96"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="115"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="150"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0013404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="218" mass="23297" checksum="C6A2186B079256D0" modified="2023-09-13" version="1">MERKDANETFYRRPVTAAELLGGVVPPPPQADILYRALNAKTSSHGSSHLSSHVSSHGSSHVSSHANNFEHDKDSNHHPTGINHSVTTSYSKGTDNFDSNADANDDPAPAYTPSAVPNIQETAITNSGHGRSSSDNPSLGSYSSTDTRPRAPPPPPPPVSTKPDIVTALYDFSGEQATDLSFKKGDIITVIKKTPSKNDWWTGRCNGSEGSFPANYTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZW5</accession>
    <name>A0A9P6SZW5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Adenylate cyclase-associated CAP C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_010440</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000726">
        <property type="protein sequence ID" value="KAG0014440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZW5"/>
    <dbReference type="OrthoDB" id="2522835at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007010">
        <property type="term" value="P:cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013912">
        <property type="entry name" value="Adenylate_cyclase-assoc_CAP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016098">
        <property type="entry name" value="CAP/MinC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036223">
        <property type="entry name" value="CAP_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08603">
        <property type="entry name" value="CAP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69340">
        <property type="entry name" value="C-terminal domain of adenylylcyclase associated protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Adenylate cyclase-associated CAP C-terminal" evidence="2">
        <location>
            <begin position="40"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0014440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="247" mass="27595" checksum="DD2DD494986E0596" modified="2023-09-13" version="1">MISVKDQAKALSNSATRPNAKENATHLIRDAKDDTQEVQVPDRKALYFLNCENCEYTVQGKPIKLSIENCKNLVLKVEDKILTGTVDIWKSGNLSLHFDRSVSTFQLDNIQSIAVRLPDAEHFGSMVWAGCEDVNLHLGRLFVAMLVLDGGLSDRTDLILTFIRLETSMETGGDVHTLSYTDLQSRNPSLRPETDQFKTTVVDGSIMTEAVVRLDNGFPATRAEQANLRQLEKQKDELLRGSQAEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0C4</accession>
    <name>A0A9P6T0C4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13">Branchpoint-bridging protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BGZ80_009816</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Necessary for the splicing of pre-mRNA. Has a role in the recognition of the branch site (5'-UACUAAC-3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the BBP/SF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000621">
        <property type="protein sequence ID" value="KAG0015512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0C4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000243">
        <property type="term" value="C:commitment complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045131">
        <property type="term" value="F:pre-mRNA branch point binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048024">
        <property type="term" value="P:regulation of mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02395">
        <property type="entry name" value="KH-I_BBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1370.10:FF:000024">
        <property type="entry name" value="Branchpoint-bridging protein-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045071">
        <property type="entry name" value="BBP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055256">
        <property type="entry name" value="KH_1_KHDC4/BBP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032570">
        <property type="entry name" value="SF1-HH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047086">
        <property type="entry name" value="SF1-HH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11208">
        <property type="entry name" value="RNA-BINDING PROTEIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11208:SF45">
        <property type="entry name" value="SPLICING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22675">
        <property type="entry name" value="KH-I_KHDC4-BBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16275">
        <property type="entry name" value="SF1-HH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 13" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="9 13" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="10 13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="13" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="7 13" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 11 13" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="15">
        <location>
            <begin position="224"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="15">
        <location>
            <begin position="249"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="130"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="297"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="440"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="321"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="356"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="387"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="14">
        <location>
            <begin position="440"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU367126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0015512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="461" mass="49796" checksum="3E1D7BFD3E049275" modified="2023-09-13" version="1">MPTALPTNMTEEQLGMFLLHTRLEEISRKLKTGDVLPADRERSRSPEPVYNAEGKRVNTREYRYRKKLEDERHSLIEGAIKKYPDFRPPSDYKRPTKTMDKVYIPVKEFPEINFIGLLIGPRGNTLKKMESESGAKISIRGRGSVKEGKSSRTDSASSANQEEDLHCLVSADSEDKVAKAIQLINKIIETSASVPEGQNELKRMQLRELASLNGTLRDDENQTCLNCGALGHRKYECPEIHNVTINLVCGICGGHGHATRDCRERNNPEAAEKAQQRNQKIDSEYLNLMAELGEQVPAGLTGSSGAPSASERDGSNGGSSYGPSSARSSSGSAPPPWANRESRDSPNQNSAPPPWAARAAATAAAHSSAPPPWQQHGAPGTNPSPSPSSAAAPWQQSSVPPTSNPWNVPAADHSAPPPPPGYPGTAYSYPYAGYYTPYGAPPPPPPVAPPGWVSSTPDKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0L4</accession>
    <name>A0A9P6T0L4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_009301</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000543">
        <property type="protein sequence ID" value="KAG0016319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0L4"/>
    <dbReference type="OrthoDB" id="5667at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF284">
        <property type="entry name" value="EG:103B4.3 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="71"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="167"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="199"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="231"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="320"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="347"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="385"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="417"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="4">
        <location>
            <begin position="232"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0016319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="446" mass="47655" checksum="E0A7300FD30481C0" modified="2023-09-13" version="1">MLDQDAAMIEKQVELPIEEVVPASLVAPVIIHSTEETQEQDSENKDEKTHTVEKIDKTHDGHDDVDNEQPFGWVVVAAAFFVQALVIGTVNGYGVYQDRYEHHEYSTASTFQLSWVGTLNVVGMDLSGPLTGQFADHFGYRISAFTGALIMGASLLATSFSTQVWQLYIFQGIVYGLGASLAFFPSLSLPSQWFKRRRGFATGIAVAGGGVGGLVISPVTTALFGVIGYRWTVRVMAILHLVFIVPASILFKARVESGRDRAKRLKREQQDREKTNPTLAYAQNHGASLSTASLLIGVLNGASAIGRVSMGLASDHIGDINTLLISSLCACLSVLIVWILAGTSIPAMAVFCVIYGFFSGSFVAIVPTVAAHLCGIGRLASVTGIVYGGIALGTLIGSPVGGALLDLSDGVDYRPTQLWAGLVMAVGTVLTLTLKLMMNPKLFGRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0Q2</accession>
    <name>A0A9P6T0Q2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Restriction of telomere capping protein 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">RTC5</name>
        <name evidence="3" type="ORF">BGZ80_009480</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000572">
        <property type="protein sequence ID" value="KAG0016030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052766">
        <property type="entry name" value="S41A_metabolite_peptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005151">
        <property type="entry name" value="Tail-specific_protease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006571">
        <property type="entry name" value="TLDc_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37049">
        <property type="entry name" value="PEPTIDASE S41 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37049:SF4">
        <property type="entry name" value="RHODANESE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03572">
        <property type="entry name" value="Peptidase_S41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07534">
        <property type="entry name" value="TLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00584">
        <property type="entry name" value="TLDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51886">
        <property type="entry name" value="TLDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TLDc" evidence="2">
        <location>
            <begin position="392"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="537"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="602"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1029"/>
            <end position="1049"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="77"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="537"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="604"/>
            <end position="633"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0016030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1400" mass="157277" checksum="F432B80CE3B08076" modified="2023-09-13" version="1">MGAIHSSLTSNDNNGPNPATRPSPTPIDSSPPSWISNKLHRDFAAKFSELELLSLRQVFQQLKQNQEKTSNSSESPALQHLHQLQQSHLSKQAKKDTRPVHLPPGITEPTFMEYLGFPSEKTRAGHLFFRSFCNLSLYPDSPHALPGHGQPPTLTLKDFIKPLALFCQKVNQETLMDVNPLKAIFESFAETGVSSPALHDTTIPAPAATTLVTDNSAPLNDQTSLKRTKTMEDSLRDLASNSNFEWSPDDEDTVDTGPSVKALDLIEVINGLLWLIQKIAVIRSNNNLGALQTEVSDSHLRRRATSIVEQMIQYSRTSDVLAPVDLSLELIDVETFSKYITRNAPNIFEVLSPYFYNLFLIGNTLSLSDATPESKFILPGVSSIPEMDSPSSIITPEHIALISWFLPLKKSTPSLTKLYNGSQHGFSMNQFEVHVCKYPAPTLFLLLVERQKTVAPTLNRRQSISFGNTTLRHKNSINNNSPTYSHYSTWGSDSRKSFDKLIGRSPTTPVSAGSVLSTIFDNVPPSTTNAITAQPNEVQSSSFAQRDSLGNTSAIAKPRRLEKERLILGAYVTETWKVSKAGWGNDAFALFEISPCFEVFPARKSSSSTTPSSSTKSLPIRTGARGTSTATTSANQQNRHYVHFLKNVGVGFGGQESESCMLYMDDNLQYGSYRQDFAGGNIYMNAGGTRQSGFEINFEIIECEVWGLGGPDAKARQKKEWDFEQREANRRASIHIRGKGDQEIDMDLLEEPDPVLLPGTEPNVEEDPCKTLGQLEEPDITFTHVKKCYENIPFNATEASNALSTLYTFFKDYYIFLDAAMLDNHPKPFTTPSVDILAGFDILSRQQYHGDFEFQTTVDNLVNTLNDAHANYLVNCYRHYLFVQPFELYAPVVNNVQTVRILTDNSYMDFEECEVLTIDGVNALDAIQNYADKYTGFSKDAGVRLNKALSANSFNAATKKWELNPGLFTTRSTLPERQTMIYRLKCPASTAYPEGLDRLVESNWEVYRLVSWNSFDSSESFLEQNCYKDTDPRKQDKRRADTFQADNEKTRRHDWNVQAAIEPPHRDTIHPLRKIRKRQYEEGQVAWLIYNGSSTAFYQLTKRPSIGVVVIPTHSVDLEKESVIMEEGFARLYSSGVRNVILDLTSNGGGYVNFAYDLVDWMFPVDNQTSVYQSDLRASASLKALAEADLANEDYSGYYNPGSFSDVITKKDYDTNFFMQDRLVKRAQRRIGYTPLVYMNHNLGAFEMDMPWQNDAERIVVLTDGACGSACGMSLNRLKNTHGVKSYAVGGRVGEDLSLFSFPGASVYSLDAILEDFENLGVDSPMQPMRYKGMYRVPILEFYQEGETMPIEHNPKLYKADFHLDYTPITARYHEVLWEIVANNHWQQDNQTGDDPSIEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T103</accession>
    <name>A0A9P6T103_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="20">Phospholipid-transporting ATPase</fullName>
            <ecNumber evidence="20">7.6.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">BGZ80_009046</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15 20">
            <text>ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.</text>
            <dbReference type="EC" id="7.6.2.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-L-serine(out) + ATP + H2O = a 1,2-diacyl-sn-glycero-3-phospho-L-serine(in) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:38567"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57262"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="17">
            <dbReference type="Rhea" id="RHEA:38568"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out) + ATP + H2O = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66132"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="16">
            <dbReference type="Rhea" id="RHEA:66133"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 19">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endomembrane system</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Golgi apparatus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 20">Membrane</location>
            <topology evidence="2 20">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 20">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.6.2.1" evidence="20"/>
    <dbReference type="EMBL" id="JAAAID010000514">
        <property type="protein sequence ID" value="KAG0016656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T103"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140326">
        <property type="term" value="F:ATPase-coupled intramembrane lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032456">
        <property type="term" value="P:endocytic recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045332">
        <property type="term" value="P:phospholipid translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006892">
        <property type="term" value="P:post-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000010">
        <property type="entry name" value="Phospholipid-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006539">
        <property type="entry name" value="P-type_ATPase_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032630">
        <property type="entry name" value="P_typ_ATPase_c"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01652">
        <property type="entry name" value="ATPase-Plipid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092:SF150">
        <property type="entry name" value="PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092">
        <property type="entry name" value="PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16212">
        <property type="entry name" value="PhoLip_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 18 20" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10 19 20" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14 20" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 19" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 18 20" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 20" id="KW-1278">Translocase</keyword>
    <keyword evidence="6 20" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 20" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="344"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="377"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="427"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="470"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="508"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="531"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase C-terminal" evidence="21">
        <location>
            <begin position="313"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="261"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="267"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="287"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="290"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="291"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="291"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00008109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00034036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00049128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00051303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="RuleBase" id="RU362033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF16212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAG0016656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="639" mass="73103" checksum="68537D3A33D5F4A7" modified="2023-09-13" version="1">MGYKFTTRRPRSVNIQVGHHDLEYEILNVCEFNSTRKRMSTIVRGPDRKIKLYCKGADTVILERLSPDNEFVDATLQHLEDYATEGLRTLCVAMREIPEKDYQSWSQVYDRAATTIQNRSEELDKAAEMIEKDLFLLGATAIEDKLQDGVPETIHTLQQAGIKVWVLTGDRQETAINIGYSCKLIQEDMSLIICNEPTHWETKEFLETKLKAIRSTLQRGDDIEPLALIIDGKSLGFALEKDIEKVFLDLAVMCKAVVCCRVSPLQKALVVKLVKRNLNSILLAIGDGANDVSMIQAAHVGIGISGLEGLQAARSADFAISQFRYLKKLLLVHGAWSYQRLSKLILFSFYKNICLYTTQFWYAFYNGFSGQTVYESWTISLFNIVLTVLPPLSLGIFDQYVSARMLDRYPQMYMLGQKSEFFNVRTFWGWASNAIYHSVVLFFAVAFIFSNDLILSNGTIGGAWVMSVTLYTAVLATVLLKAGLITEYVFFAAILWNKYAYISIPGSMIFWMGFFPIFAVVGAKIGLTPEYYGIVAALYTQPTFWLSIVLLPIFCNLRDYTFKYMKRTFFPRTYHYVQEIQKLNIPDYRPRMERFRKAVHKVRNIQRLRRNRGFAFSQNESGTGRLIRAYDTTAQKPRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T175</accession>
    <name>A0A9P6T175_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008629</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000473">
        <property type="protein sequence ID" value="KAG0017089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T175"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318:SF190">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="490"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="618"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="699"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="844"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="922"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="507"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="628"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="659"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="928"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="940"/>
            <end position="974"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0017089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="991" mass="106834" checksum="FCA17F8801E0A808" modified="2023-09-13" version="1">MVGEISINESSETAEVTEIVEEVDDIPETGDAITGILDPAINGTINGTQGIQDQPATQPLSPILASTSAAAQLSISSDAHLSYDPHQTLVSVLTQNHSRAATSSSSSSPPRPFLASWPLTMEQTQSLVYLDLRHAVVTDSLVVSLSLNCHRIEFLKVATHWQHHPHCYSVTDHALACLVAAQQGLKLVHVENHREVSQGHELVRTIDVLASHHGSTLETLVLKLHDFQNCNLAALGKSCQKLTKFAAPGGMHLFREEVTKLTDACKLTLEHLDFSNSDIETDCLTSIMKGTSTPAAARGVLKALVLLGMEDTLNQETCLAIGEYGSGLDCFRLDILESEAKDVSLMLSRPCGQNLRVLTLGCHDVHGDLANNILEQIALNCRNVELLDVNHWQFSAKAIEDVLRDCGMLRYLNVSYTDITESTADVICRCLGEVKMRLHTPVGPSSDDSLSTPLPIDVVSSQLQTLAPAHSEEGLALDAIPAQEEWIDEETHARDVETEGEISGNLDEERPDSMRKRGTEMRVKDGEETDEAYVDTNMDSDLQHVIPVFSANGGGGSGVKKQSQLGLVHHYSNVMDLRTIMNLDLDEAIEMDISAGIDGDTDMDLDMCLDLQRYHRNNSYKNEGCGDDREDDDDDDDDGDDGTVERDEDIEMMSEDDEAIARPKEPKGKEVYVGPDYDDSSQNGASSIFSAIGPVYSSSYGSTSSSSSSSSTSGSCSSSTFVTSVVETNQTQSGQVPLTAEASMQDSFLCTPLLPPLPIPSKQGGILGTDPVAVLTCTSVPSVNDQIQSAASPIPEVSSNQSKILNGFDSSNLHTPTHPMTTGAEVDDLETPLLVDGGETTQSLAPAAKQSLEPETESEESLSLSLAWTKTSRLEQGRKKSRIWVENEHDMMMTRLAMERGPELPVTTSRINEVAAETNSGASIVTVSNDSNANGNSDSQLPPTSGSEESMETADQQEAVQGSQLYQESTNGLSTHEDESMTAATTVEVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1G9</accession>
    <name>A0A9P6T1G9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HCP-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_007379</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000376">
        <property type="protein sequence ID" value="KAG0018280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1G9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="94"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="13"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="100"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="122"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="155"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0018280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="549" mass="60787" checksum="795583E65CDE62D4" modified="2023-09-13" version="1">MSDAKQEQHPLIRQSNESNDLIGMTSSPGIEITTDLESNSEEDSTPRNDIDLVSSSLSNDYINSVHVIVDTQEVETGIESSIALSMNQGDYLKPTTELDTNTTAPQTTTTTTTSAIDEVEQDQTVPQNKGSPGSTVLYSTDSITQVPESNPDPKNSNDDRNDQTRRSTEGSVSIIPIEGHIAAEDHERRDMEDNYNQGITYYHGKDVAVDYPKAFEYFLKAASHGHLDAHNKLGYMYSRGQGVKKDLDEALKWCQIAADNGYAKSQYNLGVKYQEGQGVPKDYVKAAEWYQKAAGQGFVGALNNLGIMYENGYGVAQDFAKAMEWFEKGANLGDTKAQYNIGTLHYHGKGVARDPYKAVEWYEKAVSGGEPVAQYNLAIMYQYGDGVAKDYTKAVELYQMAGNGGHVVAQYTLGTMYQDDSDIVRDYSKAAMWYQKAADQGHIKAQSNLGLMYQNGNGVSQDYRKAIELYEMASSQGDSEACCNLGFMYENGHGVTQNYSKAVEWYRKAASQGHTKARHGLGLLYYYGGGVPRDISKAMEWWEMAAIQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1Y3</accession>
    <name>A0A9P6T1Y3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">pyridoxal 5'-phosphate synthase (glutamine hydrolyzing)</fullName>
            <ecNumber evidence="3">4.3.3.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">SNZ1_2</name>
        <name evidence="12" type="ORF">BGZ80_005982</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>aldehydo-D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + L-glutamine = pyridoxal 5'-phosphate + L-glutamate + phosphate + 3 H2O + H(+)</text>
            <dbReference type="Rhea" id="RHEA:31507"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58273"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
            <dbReference type="EC" id="4.3.3.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; pyridoxal 5'-phosphate biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the PdxS/SNZ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.3.6" evidence="3"/>
    <dbReference type="EMBL" id="JAAAID010000295">
        <property type="protein sequence ID" value="KAG0019327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1Y3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036381">
        <property type="term" value="F:pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042823">
        <property type="term" value="P:pyridoxal phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008615">
        <property type="term" value="P:pyridoxine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04727">
        <property type="entry name" value="pdxS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000001">
        <property type="entry name" value="Pyridoxine biosynthesis protein PDX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01824">
        <property type="entry name" value="PdxS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001852">
        <property type="entry name" value="PdxS/SNZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033755">
        <property type="entry name" value="PdxS/SNZ_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003215">
        <property type="entry name" value="PRK04180.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00343">
        <property type="entry name" value="pyridoxal 5'-phosphate synthase lyase subunit PdxS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31829">
        <property type="entry name" value="PYRIDOXAL 5'-PHOSPHATE SYNTHASE SUBUNIT SNZ1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31829:SF0">
        <property type="entry name" value="PYRIDOXAL 5'-PHOSPHATE SYNTHASE SUBUNIT SNZ1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01680">
        <property type="entry name" value="SOR_SNZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029271">
        <property type="entry name" value="Pdx1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01235">
        <property type="entry name" value="PDXS_SNZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51129">
        <property type="entry name" value="PDXS_SNZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0704">Schiff base</keyword>
    <feature type="domain" description="PdxS/SNZ N-terminal" evidence="11">
        <location>
            <begin position="31"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with D-ribose 5-phosphate" evidence="8">
        <location>
            <position position="105"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="259"/>
            <end position="260"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR029271-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR029271-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0019327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="318" mass="33947" checksum="096867058EA930C0" modified="2023-09-13" version="1">MSFSTPTNLVPAQESTNGLSASSEVPEVASFNVKAGLAQMLKGGVIMDVINVEQALIAEAAGACAVMALERVPADIRKNGGVARMSDPKMIREIINAVSIPVMAKVRIGHFVEAQIIESLGVDYIDESEVLTPADEANHVHKHDFKVPFVCGAKNLGEALRRINEGAAMIRTKGEAGTGNVVEAVRHCRTVKAEIRKAQLMDDSELFTYAKEIQAPYHLLKETAKLGRLPVVNFAAGGVATPADAALMMQLGCDGVFVGSGIFKSGDPAKRAKAIVQAVTHFKDPKVLAEVSEDLGEAMVGINISELPEDQLYSKRGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T260</accession>
    <name>A0A9P6T260_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ATP-dependent RNA helicase DED1</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">ATP-dependent RNA helicase ded1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BGZ80_006301</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">ATP-binding RNA helicase involved in translation initiation. Remodels RNA in response to ADP and ATP concentrations by facilitating disruption, but also formation of RNA duplexes.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the DEAD box helicase family. DDX3/DED1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="JAAAID010000310">
        <property type="protein sequence ID" value="KAG0019111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T260"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17967">
        <property type="entry name" value="DEADc_DDX3_DDX4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000397">
        <property type="entry name" value="Probable ATP-dependent RNA helicase DDX4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044763">
        <property type="entry name" value="Ded1/Dbp1_DEADc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 14" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="16">
        <location>
            <begin position="83"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="15">
        <location>
            <begin position="114"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="13">
        <location>
            <begin position="83"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00025161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0019111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="394" mass="45196" checksum="F236480D834B7887" modified="2023-09-13" version="1">MNDTIGGWGRRETGPLIPLSWASEQRVYEWRSNYTEETAPHDPELESELFSFENRINSGINFKNYAYIKVSVKDGPPGMHPLENFEDSNIHPTILDNIHKMRYTEPTPIQKYAIPILLKGYDLMACAQTGSGKTAAFLVPIISALVTKIFQGRLQTKRRQPGSGYLKASPLYLIILPTRELAIQIFEEARRFTYRTPLRPVVIYGGSEARVQRDQVTRGCDILIATPGRLQDMMERGAISLAHVRYVVLDEADRMLDMGFEPQIRKIMLNSDLPRDESLQTLMFSATFPREIQVLARDFLKENCSRLRVGRIGGTTSDITQRVLLVEEYEKRDILVESLLQYPPSRTMIFVETKRTADNLDDFLYNMKFPTCSIHGDRTQAERELSLKAFRQVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2Y7</accession>
    <name>A0A9P6T2Y7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004859</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000243">
        <property type="protein sequence ID" value="KAG0020058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2Y7"/>
    <dbReference type="OrthoDB" id="5404599at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="423"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="565"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="664"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="767"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="423"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="441"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="457"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="484"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="566"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="595"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="607"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="620"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="635"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="673"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="688"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="767"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0020058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1034" mass="115091" checksum="4AE521C00ABCA684" modified="2023-09-13" version="1" fragment="single">ALDRNSKDVAQTFDDITVEPPKPIGLTVLSSRALSKLPQRTGQASHGPAGSSSEFSQTLDHRPSSLTRLEQNASISRSQARLIESSKYFECSDPSTCPLPPIPSSSLPRQRRKSSAPKLAVHPHHQPPKQIPGSAGGLAAVRHDVKVLSNVERRQRNNSINVKESRPSSWFDQDATIYCSYRTRESVCDKIHDRGDISRLEFNPSSSLEPDDDRFSSASAASAASQLSPLSPLSPLAVLQNRLSRDKGDYVEPRHCMAENFLCWPTKFIHPTAATTTSTVGHGIHISVVEYEQAQLINALVALEKLDSHPESTCRFPQQLFDLLKRILYIAHDELLFAGSNLDLVPRRRVIAKVPFEKRAFNPSSIFTGTTTVFTHNHLDPTSFIINRQSGGILALFNFQHAGFLPSYTENVQTPFIETTHSSFWNVGNPPESSSGDSFGDETKKKSRLSLDKRPKFMSFMTTSSSSSSSSQRNQALQIKERSSISSSHQNFSLVFSPQPCPQRQQEQQEHQKRKQPQGQRQQETEKDFSSSVLRRISFSASYPVINHYPAKGFHATCESIEYSESRPSNSVTESSSSGTTALDTLKRPRFTGEFNRKNSSDKNSVRIRTSIQGRHSLSTLDPTTTPNQPPDQEGSLSPKSPRVNQSGWTEFMECYRDLEQKGNRRSRIRKASTASMVSTITRTSEQNNSVSSLPPSLSVGKTKDSAHFENGHDSKALEALVSISKTLQNLVVVLEAGGIVLTPDQLLDAVARKKEEWEQEQFEKIKMDQERQHSETAAEGSTFLGIQPPISNTTTTTTTAATTVINNERLQTPTSRPSGFLKTIFQMITKKKSKRESSSIMSMYRPERTSSDNILYSAPGVQRDPLPSELPDHLFLQRHLSSPSLSSSESSATTESNLNSSMIGLRLKPNEHEEIIVPITSNPILGSITARKMPAFGIQLSNLERTKALAQIEMEKIEAQERQFWREFEGLCDRLEDCNANDNNNVRETYPGLALLRLDDLESCLEIVEGYVSSLEVQAAKYYSSLEKKSKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3D4</accession>
    <name>A0A9P6T3D4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF3020 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_001611</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000137">
        <property type="protein sequence ID" value="KAG0021837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3D4"/>
    <dbReference type="OrthoDB" id="5595797at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021386">
        <property type="entry name" value="SPP41_DUF3020"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11223">
        <property type="entry name" value="DUF3020"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3020" evidence="2">
        <location>
            <begin position="51"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0021837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="259" mass="29228" checksum="22EC0C5D0A3A1CE1" modified="2023-09-13" version="1">MIRDDTAFQTQDLIAATANATSAVTTGATASVDPVQSLKRELNSEKVRTENRERKKRWREQNEDRNKDNDLRCRVNKRANTLLGTHDSEHKTRWIEEEFAKRQLKRKEKERRRNPNAASLEPLPAPPKSTVSLNEHIALQRQAQQAHVQHQSQQLHAQLAHPQFDPNTVKTALALNDLVKKNGSHLDLAQLTGVLTDPNLARQLIEIEANNPVAPPPTVMVMNTPAKPDHEPKGNHMLEADYPMDAVLTLMQLNGSWKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3X6</accession>
    <name>A0A9P6T3X6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tyrosine specific protein phosphatases domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_009595</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000059">
        <property type="protein sequence ID" value="KAG0023368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3X6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43180">
        <property type="entry name" value="3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (AFU_ORTHOLOGUE AFUA_6G11210)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43180:SF63">
        <property type="entry name" value="DEHYDROGENASE_REDUCTASE FAMILY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G03520)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="4">
        <location>
            <begin position="81"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="142"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="142"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="162"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0023368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="454" mass="49709" checksum="B38369132E55985A" modified="2023-09-13" version="1">MARFNISPIKVDSLSFLILDCPSDETLFKYIPVLEEHNTTDLVRVCEGFPYNIQPLTDIGIKVHDDMKFEDGTVPNERIVAKWLELNEEIFFDTPTPDRCIAVHCMSGIGRAPDAIAFIRATRRGALNSTQIAYLNRRRKKGFNKKSRKRNGRSKSPSGRICGKEDPSREKLTLGPSTTTLTLEEDENCSKKKGGFLGIGLESSVLFASEGAQVVCADINEKGAAATVEKITSLFGAGRAVSIRADVSKEEDVKKMIHLAVSQFGKISVLFNNAGIMHPADDNALTTPESIWDLTMNINVKGVWFGCKYAIEEMRKTGGGSIINTASFVALRGAATPQLAYTASKGAVLAMTRELAVVHAKENIRFNSLCPGPLRTPLLMEFLNTEEKKNRRLVHVPMGRFGEAIEQAKAALFLASDDSSYMTGTEFVVDGGLCSAYVTPEGETISNSPHVSYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T463</accession>
    <name>A0A9P6T463_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Protein kinase C-like 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">PCK1_1</name>
        <name evidence="1" type="ORF">BGZ80_000301</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000106">
        <property type="protein sequence ID" value="KAG0022407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T463"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004612">
        <property type="term" value="F:phosphoenolpyruvate carboxykinase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.228.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001272">
        <property type="entry name" value="PEP_carboxykinase_ATP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013035">
        <property type="entry name" value="PEP_carboxykinase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30031:SF0">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYKINASE (ATP)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30031">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYKINASE ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01293">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53795">
        <property type="entry name" value="PEP carboxykinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0022407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="133" mass="14647" checksum="C83E4FE952B8150D" modified="2023-09-13" version="1" fragment="single">PFLVLHPTQYATMLAQKIQQHTADVWLINTGWNGGVYGTGKRIALKYSRAIIDAIHSGELKNAQYETYPIFGLEIPKAVTGVPAEVLNPAVAWQGTKEEYNATVTKLANLFNENFAKYQDQATQDVIAAGPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T465</accession>
    <name>A0A9P6T465_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_009597</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000059">
        <property type="protein sequence ID" value="KAG0023370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T465"/>
    <dbReference type="OrthoDB" id="2349664at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="299"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0023370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="545" mass="61358" checksum="949F167D7086588B" modified="2023-09-13" version="1">MKIYLEAVPRLPRLECVEFYDIRNWDSGNVEEAITFVREHDRFAIRSQRRFQKDATQAVVGQASSHDNVHEEGSEKMMMAKLIEIKLGGSGDSGIIQTTELYKILQAMQHPKVVDLTEWKGAVMDIMQIPVKTLQVLKMRLDRPLPKTCPLGNFLLRARSLRELQISIAPTHGRLFRWAVKRMQVRKQMYKMARESQNGSQGRTSEVRDLTGTVSMDGAKRRQGRFQQCISDVKEEGLEVLSLAGETATVVQALNAAAWGFSNTLKTLHANTWKENSGLQFEDVAVGVAPQADNTIEPGLDDNMDPTDGDDDNTDEGSSDGSTGVANNPAGPLSSIVRFSFNHKIPMIRLHTLELKGEVATIALDFQSLRHCPQLCTLRLNTRPCRVEPDIDAVDKILANVPGSLTDLEFIGLWWITDHHLNQIAKCLSKLRRLRIGHAPSFYTITPMSTPIMSYQSPESLSCAGIAHAVEQLRELRELWLGVDMDYYRRRRERNSGSSMLSFFSRRIAGNEKEEDIWATLVDTIGHQSEKRVIPLAIEIQHCPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MC53</accession>
    <name>A0A9P6MC53_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_008853</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004954">
        <property type="protein sequence ID" value="KAF9991845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MC53"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9991845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="75" mass="8308" checksum="F798E6B4782A429C" modified="2023-09-13" version="1" fragment="single">EPSADLTWAIIRGALKVIGIQTRYFEIAILGVDARKNFGKNLTDGVAFAGKQQIYLAEASPLYDTTAEKNRTIHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MDN7</accession>
    <name>A0A9P6MDN7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Alternative oxidase</fullName>
            <ecNumber evidence="13">1.-.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">AOX2</name>
        <name evidence="15" type="ORF">BGZ80_008044</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="12 13">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="12 13">Binds 2 iron ions per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the alternative oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.-.-.-" evidence="13"/>
    <dbReference type="EMBL" id="JAAAID010004248">
        <property type="protein sequence ID" value="KAF9993743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MDN7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098803">
        <property type="term" value="C:respiratory chain complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009916">
        <property type="term" value="F:alternative oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010230">
        <property type="term" value="P:alternative respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.140">
        <property type="entry name" value="Alternative oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002680">
        <property type="entry name" value="AOX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038659">
        <property type="entry name" value="AOX_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31803">
        <property type="entry name" value="ALTERNATIVE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31803:SF3">
        <property type="entry name" value="ALTERNATIVE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01786">
        <property type="entry name" value="AOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005229">
        <property type="entry name" value="AOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0249">Electron transport</keyword>
    <keyword evidence="10 12 13" id="KW-0408">Iron</keyword>
    <keyword evidence="11 13 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 12 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 13" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="5 13 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="60"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR005229-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAF9993743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="255" mass="29533" checksum="DB5CAA05C2CDAC63" modified="2023-09-13" version="1">MRDEFMGKKRLSTKDLEAIPIDLGFHREPSNASDWVAYQVVKSMRIPVDFFFRKKYIHRVVALETVAAVPGMVAGLLRHLRSLRRCSHDGGWISHLLHEAENERMHLLTWMKVAQPTILERLLVTAVQGVFFNVFFTLYILSDRTAHRVVGYLEEQAVISYTHMLDEIKAGVLENGPAPKIAIDYWNLEETATIRDVCLAMRLDEAVHMHTNHHLSDRIALKQEDLRVDIHKLQEERGMIPKDNAEEVWSKPNKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MDR0</accession>
    <name>A0A9P6MDR0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Condensation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007977</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004199">
        <property type="protein sequence ID" value="KAF9993928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MDR0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043041">
        <property type="term" value="P:amino acid activation for nonribosomal peptide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19544">
        <property type="entry name" value="E-C_NRPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensation_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF1">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Condensation" evidence="1">
        <location>
            <begin position="23"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9993928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="372" mass="41312" checksum="66631B604CF0459F" modified="2023-09-13" version="1" fragment="single">MATKGDPYLLVGKMSFDNRDILDRYLDAVQKVVDRHDILRTAIIWKNLSVPTQVVLRHVKLSIVELSLDPAHGDIIDQMTELTDPRRHRIDLTQAPLVRFVIAQDTDGCWFAVELLHHIIGDHSTLDVMGAEVQAFYYNRGDTLLQPQPYRNLIAQARSRTDSSSVHEYFFTKMLGEIDTPALPYGMSDVHHDGLDVTESHLTLPQNLNDKLRGHSKRMGVSLASLCHLAWARVVSKTSGQERVVFGTVLFGRMQGGSGSDQTMGLFINTLPLRVDIGSSSVEKSVRQTQADLAALLEHEHASLALAQRCSSIPTGTPLFNSLLNYRHNTKQSSEASDIRGVKMLDGQERTNYPFTISIEDGGSTLGLTAQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ME81</accession>
    <name>A0A9P6ME81_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_007748</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004012">
        <property type="protein sequence ID" value="KAF9994683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ME81"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="323"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="380"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9994683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="467" mass="50783" checksum="F7A1DF788F30677D" modified="2023-09-13" version="1" fragment="single">NIPGAVAGQRYTPKSYPYVTGCDSMNLDLLLNADSDLTFPISGGCATAGIAFSSNFIPNISTVRVANTSENRLSITVDGTNATPDILSMISPAPFLIKDGFMCGTADDSIDVFIPTNRLTSLPQTLVTKCVLPSGEVRVISLSTIKFSPTGPEVFRAVTETILDGYDELLQAMEFALGNAAYASTCTMFLEVKSNNSSIDAVSCYSLKSQLLNTNGLSCVYFNINMLILEQQEISLDITNAREGMPLQLQPNITLAMAIRHVPKISLTALERTPISMMKGASLAAAQYMASLGQNVYADYLEEQLYVVFDVADIEEGLLIPDWLVAVVCTLTGLCFLLWGWTKKYLDIVYTSSLYGIVSKSIKGESHVIMRSKINPLQVDDRHIVPDNDDDNDNDTRSDGYNGNDTHSDFAETMAERIPQVENATSMEEIEMADIAVSMEETEMTDTAVSMEKIGTTSVEGASELNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MEJ6</accession>
    <name>A0A9P6MEJ6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007471</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003836">
        <property type="protein sequence ID" value="KAF9995582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MEJ6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9995582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="227" mass="25211" checksum="C34ED04A74053DFB" modified="2023-09-13" version="1" fragment="single">MSKEGEYEPLQIFRAVYKDKTSGTFIPLTETVKIKPWSVSESGEHIILWSDIKAAFGNPVHTMRKDVILPFLADENSEALQPLRISVHPGDVIDVMIEDPGIDITMRSLRIQNPPATSSSSEIPAAANSSSPSTKLENIRQAQQRGKSRQDGGEPLENTTCTLQEPRSSDRAHQLASDYKDNGLCCCDETEPAIDSQHHNDVFVYRGDEGKADEDYVRGLAYYEGKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MEM9</accession>
    <name>A0A9P6MEM9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_007686</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003985">
        <property type="protein sequence ID" value="KAF9994807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MEM9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9994807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="469" mass="52327" checksum="A59D287CE5690FF2" modified="2023-09-13" version="1" fragment="single">IGTGAHRAIHEPSKAAMLKTPRVDQTLLPEEQATYPRGNCDEHENPARPEKALDIMAHNAVHKYESLNAVILKTPRVDQTLLPEEQATYPRGNCDEHENPTRPGNICNIMEIGTGAHHAIHEPSKAAMLKTPRVDQTLLPEEQAIYPRGDCDGHENPVRPEKIFNIMEIGTGTRHAIHEPSKAAVLKTPRVDQALLPEEQATYPRGNCDEHENPAHPEKVFSIMEIGSGDRHAVHEPSKAVMLKTPRVDQTLLPEEQATYPREDCDGHENPARPEKALDIMAHNTIHKYEPLNAVMLKAPRLDQTLLPEEQATYPRGDCDEHENPARPGKVFNVMEIGTGARHATYKPSKAAMLKTPRIDQTLLPEEQATYPRGNCDEHENPACPEKALNIMAHNTIHKYKPSNAVMLKAPRVDQTLLPEEQAIYPRGGCDEHENPARPEKVFNVMEIGTGVRHAIHEPSKAAMLKTPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MEX2</accession>
    <name>A0A9P6MEX2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PAS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007481</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003844">
        <property type="protein sequence ID" value="KAF9995536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MEX2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAS" evidence="1">
        <location>
            <begin position="19"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9995536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="135" mass="14974" checksum="F5766DD0631C73D2" modified="2023-09-13" version="1">MPPKSKTFISIHDLTPSIRFLWASPSVYDVLGYTPDEIVCMNAADMIYPEDVTNSSDALSENIKNDLVASQLVNKLRRKDGTPAHLLHVFSTCYDVLVNCSTLLDEEDDEYQQLRAHSTAMTSIVGSKEESAPPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MFC7</accession>
    <name>A0A9P6MFC7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_007194</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003640">
        <property type="protein sequence ID" value="KAF9996660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MFC7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9996660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="197" mass="22019" checksum="24B54442E7740D1E" modified="2023-09-13" version="1" fragment="single">MAGRDACWVHWAIGGCIKSMAPPSYTGATDSLPKGIETVSYFKTTKVAEWGLEGFMTATGRNEKIFLSKILNLSKFKPVPLDVSLFAKDLYDFYNGVFGEEVTTIAKDQAQSLMNRKVFRGKEQLIVQRQYKHDLENDSVCQNQTITESSAGKLESTQSSLGIPSVPSFTPMSAQSENTLMHTTIIKQEERRRKPQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MFH7</accession>
    <name>A0A9P6MFH7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Carrier domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_007183</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003631">
        <property type="protein sequence ID" value="KAF9996726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MFH7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043041">
        <property type="term" value="P:amino acid activation for nonribosomal peptide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19544">
        <property type="entry name" value="E-C_NRPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1200.10:FF:000005">
        <property type="entry name" value="Nonribosomal peptide synthetase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF1">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="4">
        <location>
            <begin position="32"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="624"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9996726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="624" mass="69323" checksum="55D39FC045FD76A6" modified="2023-09-13" version="1" fragment="single">MDAFPLTNNGKIDRRALPKPDDASLVGSVYEEPQGEIEVELAKVWSDLLKIDRVGRQDNFFMLGGHSLMAIRMIELLRQRGLSLSIRALFNKPVLHALAASHGRQQSDLEIPSNLITTETTKITPNMLPLIDLSQEDIDLIVSQVPGGVANIQDIYALSALQDGILFHHMLATEGDPYLQVACTAFRDKELLDRYLHAFQKVVDRHDILRTAFVWKNLSTPAQVVLRQATLSVVEHSLDPSNGPVVDQLMELYNTRNYSMELNSAPLTRFAYAQEGDGRWILIQLLHHLIDDNTTFKLMSAETKAIMAGQDGDRQSPQPFRNLIAQTRLGVSAEEHEVFFRKMLGDIDNPSLPYGLSDVHNERQSVTESYQVLPQDLNDKLRAHAQRLGVTLASLCHLAWGMVIAAISGQTQVVFGTVLFGRMRGSGSDSTLGPYINTLPFRVNVEDSSVVDAAQRVQADVAALLEHEHASLAIAQRCSGVPSGMPLFGALLNYRHRANEVNETGTDTGVEHLGFHERTNYPFVLSVEDFGSSLGLTPQATQPYDPSRIGGYMQQALYSLAEALEHTPEVSIHSLRILPMEEYNLVVHSWNNTDALYPSNQCVHQLFEDQVEMAPEAVAVVHDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MFL6</accession>
    <name>A0A9P6MFL6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Transmembrane osmosensor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">SHO1_2</name>
        <name evidence="12" type="ORF">BGZ80_007035</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SHO1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003530">
        <property type="protein sequence ID" value="KAF9997334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MFL6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007232">
        <property type="term" value="P:osmosensory signaling pathway via Sho1 osmosensor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030833">
        <property type="term" value="P:regulation of actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11855">
        <property type="entry name" value="SH3_Sho1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000213">
        <property type="entry name" value="High osmolarity signaling protein SHO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035522">
        <property type="entry name" value="Sho1_SH3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15735">
        <property type="entry name" value="FCH AND DOUBLE SH3 DOMAINS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15735:SF21">
        <property type="entry name" value="PROTEIN NERVOUS WRECK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="7" id="KW-0346">Stress response</keyword>
    <keyword evidence="5 10 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="48"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="76"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="11">
        <location>
            <begin position="153"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9997334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="212" mass="23213" checksum="C63FBBB0523B78CF" modified="2023-09-13" version="1" fragment="single">IGWFISFVSLCTIGAYPHLIWVIIFYNLFLLLGTTLAIATQALHNYRLVILTFLGGSLSLLFSCIDTALIPRNSKFDALSAGLIFQSFVLVFWVFYFGSEEESLIKRSINGFTIPRTPGAASATTNGAATAVASPNQQPLDNLSSVVVAPAADYAYKARALYSYEANPEDSNELSFVKGEVLDIVDNKGKWWQARKQDGTIGIAPSNYLQLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MFV7</accession>
    <name>A0A9P6MFV7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_007150</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003604">
        <property type="protein sequence ID" value="KAF9996882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MFV7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myb-like" evidence="2">
        <location>
            <begin position="179"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9996882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="255" mass="28808" checksum="928D904ECAEBA2D0" modified="2023-09-13" version="1" fragment="single">IRKAPVNTAPKSVQPVRVSNRLRGLAVTPLEIGENDSLDRTAPQLEWGASDISQGDAKGNDDSDDESAANLMSGDLFFDQETREKAIRVDGHYKGWLNSTVMERYGFEKSAQEAWEANGGGAFSFKDPLGLNDETSSPRSKSSKRPKYDAKLVAKAMFKKNPNAFFYRHNEPGQEQWTGDWTEEEGELFLRVAREFGCGDKWGLFASHIPHRVGYQCSNYYRQVVLPQGLVFDANYEYTSRGKPIYCGKYNQRRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MH17</accession>
    <name>A0A9P6MH17_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_006408</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003161">
        <property type="protein sequence ID" value="KAG0000215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MH17"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051726">
        <property type="entry name" value="Chitin_Synth_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46430">
        <property type="entry name" value="PROTEIN SKT5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="122"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="248"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="48"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="122"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="189"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="259"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="281"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="298"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="330"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="379"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0000215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="495" mass="52825" checksum="2FCECFC919C8ED9D" modified="2023-09-13" version="1" fragment="single">MDRVNTVHTEYPQEKLAPLSHDEVDYDSYDATAQTFYKPPPPSSRHNSQTISTPTSASSSNSNWTISNGRKSSPNPGYPYEDDSNIKVQAPLDLDFGSLSLSGSDSPPGGGLVSLPLRFAEGESREPVERVGYVDDTRFSGSDYGGVDGAAVRTSTDSPRISYGSGVVLPGQDSRSRTPRRTTSIGSTHSSTKSYASPNLNSAYANSPVSQPASGEGEYVRPYIQNQQAYSYGSSVAGQDYHRQSVQIIPGRPPFRPSPTGQPYNQQYPNHDPRYQQHPGGYVGGPNGYPGGYDGSEYGQEYYQDPQYQQYYGAGYPPGPGNGPGYRPCGPGGYGPRGYGSPGQQYRPRPNGANLQPSPSMRGPPPGRGGPRPMMVGPGGPPGGPYGGRPPPHRGEFVGRPNGGPPPGSAGPRKRPLSIEVLDEMRVRAKTSNDPAAQLDYAKTLISAAASFGNDDPDPKRQRKNKEALLMEGLKIVKRLATSGVGAGRPPYPEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MHB6</accession>
    <name>A0A9P6MHB6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Magnesium-transporting ATPase, P-type 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_006357</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003135">
        <property type="protein sequence ID" value="KAG0000481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MHB6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030001">
        <property type="term" value="P:metal ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42861">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="195"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="224"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="658"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="728"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="795"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="832"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="9">
        <location>
            <begin position="8"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase C-terminal" evidence="10">
        <location>
            <begin position="682"/>
            <end position="853"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0000481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="862" mass="94398" checksum="6A299788D557FBBD" modified="2023-09-13" version="1">MNKAIVKVDIPIEDVVPGDWIQLSAGDLIPADVKVIESKDLFISQAALTGEAMPVEKFSSSSEAMAAWNTSEKNSYDCMAKDAVPIDASAITIEKNSNANLDNAPVAETGSFKDTAKRALYACFGVRLFDAETTQNAPDVGLDRPDLCFMGTSVVSGTATVIIEKIGADSFFGSMAEELSKRRPENAFQLGVRNISWVFFGIMFLMVPPVLLINGLLNKSWTDAALFALSVAVGLTPEMLPMIVNSNLARGAYLMSKKRCIVKNLDAIINFGSMDVLCTDKTGTLTENKVVLVRHLDYHGKASIHSLQLAFLNSRFQTGLKNLLDVAVVQYFEKTASVLPMYESLANDKEAGSGLTPAAVTFASRYLKIDEIPFDFVRRRMSVVLKDLANDKGLLVSKGAVEEMLSICTKIVIPRGQRSDSVDIVMGSESDNISNLDMLEEIQEDQIQTLIPEMIEHLLEMNKDLNVDGLRIIAVAYRNMESVNNNYGISDECGMTFAGLIGFLDPPKESTGPAIAELMSLGVEVKVLTGDSAAVCKKVCAEIGLPVKSVVTTTDLIGLDDEQIVELARSATIFAKLTPLQKSVVIRGLKRSGCVVGFLGDGINDAPALSEADVGISVDTATDIAKESADVILLEKSLTVIADSVILGRTTYGNTMKYIVMAISSNFGNVFSMLIASSWLPFLPMQPIHILTQNLIYDLSQTTIPWDTMDSEFLKVPHRWSMKSILRFMVFMGPWSSPFDIATFLFMWFHYRIQTADNPLVTMFQTAWFVEGSLTQLLVIHIIRTPKIPFIQSIAAPPILASSIVFSAISLSLPYIPTFQDLLSLIPLPGLYYAYLVGALCAYFTITQIAKLIYVHTFKAWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MIK5</accession>
    <name>A0A9P6MIK5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005939</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002927">
        <property type="protein sequence ID" value="KAG0002635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MIK5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040212350" evidence="1">
        <location>
            <begin position="19"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0002635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="280" mass="31368" checksum="B4C01ADD38B9436A" modified="2023-09-13" version="1">MKIQFLSLFLVVASVAMARPAPMDQASASSELAQRSLLGDLFGGDSTSISNVDDNSKHTQTMNQHGNKHITITETFKETRGGEEFFDRRDLARVSSEEGNGNAPLARRGLLFGGDPMSISNPKDEPAWKQGFVDHEKDCSSNSSSSHQKKMTRTTTRFFDRRDLLAENEESGPGIERRSLFGDLFGCSGMTINNVNDNSQTMKIYNSHGNKNVRINSWVHKNIRDNKRGLLSEWKTMSISNENDNSKETKTFNSRGNVDKKIASKVDKSFGNNNDEDEWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ML06</accession>
    <name>A0A9P6ML06_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_005187</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002576">
        <property type="protein sequence ID" value="KAG0006654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ML06"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myb-like" evidence="2">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0006654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="92" mass="10321" checksum="3DC0022D4D5A98C5" modified="2023-09-13" version="1" fragment="single">MTGKWDGDEQRRLVEAIRSQVGDEYEICLGVKEEGPKGSNQLATTTSGLDSKPALTMGSHVLRSLNWEKIASEVRTRTASQCHTHFYRSMHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MLW7</accession>
    <name>A0A9P6MLW7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_004981</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002488">
        <property type="protein sequence ID" value="KAG0007175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MLW7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0007175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="358" mass="40946" checksum="2C58213F21E1377F" modified="2023-09-13" version="1">MQIKGGCVTCQEEWPQNLDGIHLSLYKFIETKLHHPLSLSKISEKDIVTMSGIVNTRMDGARKVFGDETVEKEAYRSGGLDELLYKVEEGVGIEAKERREKRSHDQLKGRIVDAVRHIAIKSPTKDMSEAELVSVWSYVINALTGHTLALRSGEPASKATKWQRILLQQELDHDSGAATYGRKPDLQCRSEELCGATPHEFKANGRSKEQVELQYRKNLRINQSMMFYLKHHVGIGLEDLEVLALDVHGTLHFSLRYHDNVFVSDLATKHLLRLPDSTVSWKQFLSGSTLSVLLAYVEHLEHLIERIEEHTLLQEQQERIEDRQTTERELRRIGKFSFFNPAKKQCRDGSQSSNQYAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MM12</accession>
    <name>A0A9P6MM12_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphoribosylglycinamide formyltransferase</fullName>
            <ecNumber evidence="2">2.1.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">5'-phosphoribosylglycinamide transformylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">GAR transformylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_004491</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>N(1)-(5-phospho-beta-D-ribosyl)glycinamide + (6R)-10-formyltetrahydrofolate = N(2)-formyl-N(1)-(5-phospho-beta-D-ribosyl)glycinamide + (6S)-5,6,7,8-tetrahydrofolate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15053"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:143788"/>
            <dbReference type="ChEBI" id="CHEBI:147286"/>
            <dbReference type="ChEBI" id="CHEBI:195366"/>
            <dbReference type="EC" id="2.1.2.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; IMP biosynthesis via de novo pathway; N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide from N(1)-(5-phospho-D-ribosyl)glycinamide (10-formyl THF route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the GART family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.2" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010002288">
        <property type="protein sequence ID" value="KAG0007576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MM12"/>
    <dbReference type="OrthoDB" id="5575075at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004644">
        <property type="term" value="F:phosphoribosylglycinamide formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08645">
        <property type="entry name" value="FMT_core_GART"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.170:FF:000009">
        <property type="entry name" value="Phosphoribosylglycinamide formyltransferase (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.170">
        <property type="entry name" value="Formyl transferase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01930">
        <property type="entry name" value="PurN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002376">
        <property type="entry name" value="Formyl_transf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036477">
        <property type="entry name" value="Formyl_transf_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004607">
        <property type="entry name" value="GART"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00639">
        <property type="entry name" value="PurN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43369">
        <property type="entry name" value="PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43369:SF2">
        <property type="entry name" value="PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00551">
        <property type="entry name" value="Formyl_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53328">
        <property type="entry name" value="Formyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Formyl transferase N-terminal" evidence="10">
        <location>
            <begin position="4"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00041324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00041682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0007576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="206" mass="22192" checksum="8CAD0EAC4034C705" modified="2023-09-13" version="1">MAPRVVVLISGTGSNLQALIDAVNSGALTAEIPLVISNRSKVFGLERAEKAGIPSKVLALKPYTAAGRTRVEYDLDLAQLVIDAKPDLVVLAGFMHILSPEFLNQFPTTPLINLHPALPGQFDGAKAIERAFEAYQKGEIKHTGVMVHRVIQEVDGGEPVLVKEVEIKPEDDLAALQERIHSVEHVLLVQGAAIVLEEEAKKKSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMM6</accession>
    <name>A0A9P6MMM6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003960</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002080">
        <property type="protein sequence ID" value="KAG0008017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMM6"/>
    <dbReference type="OrthoDB" id="5511684at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010530">
        <property type="entry name" value="B12D"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14256:SF1">
        <property type="entry name" value="GEO09626P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14256">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE MLRQ SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06522">
        <property type="entry name" value="B12D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0008017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="90" mass="10181" checksum="0E4AB4AFEA155942" modified="2023-09-13" version="1">MSAAAHAAKKAPTFFQTWFRVEVIPIYAVLGVACGGAAWYVSRLARGPDVTWDRKNNPHPWLNIDQETQLKLMTVKEGQGFTKTYSRDRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMU0</accession>
    <name>A0A9P6MMU0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_004600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002329">
        <property type="protein sequence ID" value="KAG0007490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMU0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0007490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="133" mass="15190" checksum="1A2A410F9F95BA4C" modified="2023-09-13" version="1">MSSRRISCQTAAALSKIAKEELEDNHTNENGPSKLVGKVEMKLEDEVEIIRSRVAKRLTQNEAAKIDMVVDVTLQLLEEHGGLDMRVQPSSEDEHLHLPRNASYRLRRWSLGNEFQISSTRWKSSSRLFAMVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMV6</accession>
    <name>A0A9P6MMV6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Succinate-CoA ligase, alpha subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">SUCLG1_2</name>
        <name evidence="9" type="ORF">BGZ80_004145</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Carbohydrate metabolism; tricarboxylic acid cycle; succinate from succinyl-CoA (ligase route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Heterodimer of an alpha and a beta subunit. Different beta subunits determine nucleotide specificity. Together with the ATP-specific beta subunit SUCLA2, forms an ADP-forming succinyl-CoA synthetase (A-SCS). Together with the GTP-specific beta subunit SUCLG2 forms a GDP-forming succinyl-CoA synthetase (G-SCS).</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the succinate/malate CoA ligase alpha subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002144">
        <property type="protein sequence ID" value="KAG0007861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMV6"/>
    <dbReference type="OrthoDB" id="1664372at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009361">
        <property type="term" value="C:succinate-CoA ligase complex (ADP-forming)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004775">
        <property type="term" value="F:succinate-CoA ligase (ADP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004776">
        <property type="term" value="F:succinate-CoA ligase (GDP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000002">
        <property type="entry name" value="Succinate--CoA ligase [ADP-forming] subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.261:FF:000005">
        <property type="entry name" value="Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="entry name" value="Succinyl-CoA synthetase domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01988">
        <property type="entry name" value="Succ_CoA_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017440">
        <property type="entry name" value="Cit_synth/succinyl-CoA_lig_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033847">
        <property type="entry name" value="Citrt_syn/SCS-alpha_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003781">
        <property type="entry name" value="CoA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005810">
        <property type="entry name" value="CoA_lig_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005811">
        <property type="entry name" value="SUCC_ACL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004230">
        <property type="entry name" value="PRK05678.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01019">
        <property type="entry name" value="sucCoAalpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11117:SF2">
        <property type="entry name" value="SUCCINATE--COA LIGASE [ADP_GDP-FORMING] SUBUNIT ALPHA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11117">
        <property type="entry name" value="SUCCINYL-COA LIGASE SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02629">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00549">
        <property type="entry name" value="Ligase_CoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001553">
        <property type="entry name" value="SucCS_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01798">
        <property type="entry name" value="SCOASYNTHASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00881">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52210">
        <property type="entry name" value="Succinyl-CoA synthetase domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01216">
        <property type="entry name" value="SUCCINYL_COA_LIG_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00399">
        <property type="entry name" value="SUCCINYL_COA_LIG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="CoA-binding" evidence="8">
        <location>
            <begin position="22"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="6">
        <location>
            <position position="271"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00061754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001553-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0007861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="318" mass="33291" checksum="FFD25C89023479C5" modified="2023-09-13" version="1" fragment="single">AQRLFSSSSKVANYDKTIKNMLINKNTKVVCQGFTGKQGTFHSKQAIEYGTKMVGGVSPKKGGQTHLGLPVFSTIAEAAKELKPDASVIYVPPPMAAGAIMEAVEAEIPLVVAITEGIPQQDMVRVVKALKAQDKTRLIGPNCPGIIAPDACKIGIMPGHIHKLGKIGIVSRSGTLTYEAVNQTTNVGLGQSLCVGIGGDPFNGTNFIDCLTLFLEDPNTEGIIMIGEIGGSAEEEASEFLKKYNLTREKPKPVVSFIAGRTAPPGRRMGHAGAIIAGGKGGADDKIKALESAGVVVSQSPAKLGVLMRAEMEKAGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MN48</accession>
    <name>A0A9P6MN48_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Pumilio domain member 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">PUF6</name>
        <name evidence="5" type="ORF">BGZ80_003882</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002054">
        <property type="protein sequence ID" value="KAG0008076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MN48"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012959">
        <property type="entry name" value="CPL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033133">
        <property type="entry name" value="PUM-HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040059">
        <property type="entry name" value="PUM3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001313">
        <property type="entry name" value="Pumilio_RNA-bd_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13389">
        <property type="entry name" value="PUMILIO HOMOLOG 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13389:SF0">
        <property type="entry name" value="PUMILIO HOMOLOG 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08144">
        <property type="entry name" value="CPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00806">
        <property type="entry name" value="PUF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00025">
        <property type="entry name" value="Pumilio"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50303">
        <property type="entry name" value="PUM_HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="PUM-HD" evidence="4">
        <location>
            <begin position="76"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="40"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="14"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0008076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="595" mass="67155" checksum="9BFE61E91689BFC0" modified="2023-09-13" version="1">MAVVKRKSASITAEKPERKVKAAKVEAPAPQKKTLFGKAIDEDDDEEMATKEANAQKKALRDERRSHKPNAELIYPAKKLWEKLRLKELPKAERQAVMNDMMTLITGKVQEIIFKHDMSRIIQSCLKHGNEAQRNVIAGELVGHYLTLSKSMYGRFIVVKILHYCQKYREAIIKEFYGKVRQLIKHKEASSIIEDAYSIYANSAQRAALIQEFYGPEFRLFKVEDKKTLTEILEQNPAKKENIMKHLMETLTGCLEKGTIGFSIVHRGLLEYFEHADAKGIQEMLDVMKEQAVEMLHTKEGAQVAMLCLLYATPKDRKAMLKTMKPFVVKICKEEYGHMVMLRMFDVVDDTVLMSKAIIAEIVKEMEDIAKDKFGRRVILYLLAGRSPRYISPQNIELLAKGDIIRANTSKKDAQVRSAELRGYISPALISLVATKTRSLTSEPLACQVVLETMLHATTDRKAAVDALLELASADPAEATSEEPNPLLVMPTDRLYKTLVQSDYKAPLAEPSLHFGKALLSKISPFIGHYVLKSSSGAFVVLALLENPETADETKKLLTSKSKSITLQKEMEKLIKDKPENEHKAVRLILDVLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNH0</accession>
    <name>A0A9P6MNH0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_003557</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001948">
        <property type="protein sequence ID" value="KAG0008342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNH0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="93"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="210"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="93"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0008342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="276" mass="31819" checksum="349E8DB3A6EDCE1D" modified="2023-09-13" version="1" fragment="single">MKNKIERMQSAFKRGHALAKQAGFDIKGSESWKNKIKEICSYYFDMMDNWAVAWSDDVPEYCNSTKNLDDPFIDDVMPRRAVVDLTLDTNIRPDGEIATEEDQRMSERGGEDGEWSRKQRGKRWREDDEEDDEDGCPVRILQHPSRRRLKATRNCTRSDLAHLDATGANRRASTSKAQSKAKDKSKIESSNGSNGGKSQDLVEADRANLRDDMMAKLEELKIKRAKLMLEIMETKLKMGKQVVGERKLVRQMRLALEEMHLEMEAAKRRQQQANDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNU6</accession>
    <name>A0A9P6MNU6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Homeobox domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_002864</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001729">
        <property type="protein sequence ID" value="KAG0008965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNU6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.10">
        <property type="entry name" value="Conserved domain common to transcription factors TFIIS, elongin A, CRSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035441">
        <property type="entry name" value="TFIIS/LEDGF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017923">
        <property type="entry name" value="TFIIS_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08711">
        <property type="entry name" value="Med26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47676">
        <property type="entry name" value="Conserved domain common to transcription factors TFIIS, elongin A, CRSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1 2" id="KW-0371">Homeobox</keyword>
    <keyword evidence="1 2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="4">
        <location>
            <begin position="9"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="1">
        <location>
            <begin position="11"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="69"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="274"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="75"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="291"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="352"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="414"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="443"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0008965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="597" mass="64592" checksum="48F01E74211F08E8" modified="2023-09-13" version="1" fragment="single">MNVTFGNVVEGQKTRFTFAEKHVAKLEKVFKTEQYPNRALKAELSEFIGCSEKQVANWFDRRRIFERKTNQASANPINTSSSPSGPSVPQNGPSPSPVPSVEEDTPTDGVLGTAAFTENNSPQPKSAPVPSKLSSNKIAHKLTRLTQGNVIRKPSDVKAAIELMEEAGDSKGRIYILNTLISTKRLQPILKEFVRLKGHGLLSDWMVEAREDPGTPENRDLMRKTIEVLNELPLELDDIMVRGVGKVMNRIARNKDETVDKDTSERAAKVVKKWKDLVQGPAGSSSGSKPNGDRNGRGVKRERDDAEDRLHESTSRSLPKFNKGTPVGPAETIKKPNIVENTSFFDQLRGRPSNISTSSSTSTTNSSSTKPSSSPVSTTPVATITSPAQPSPAPATSVSKENTEAASDNVPSITEATTAPTPAEIVDTPMNLPLQHSPAAETAGNTNSSDALGATPSTDMEMDTVAADPPKKGKGKRVWWKADHELVAIRFIEPRGEVLEHEEEEVEALVRGDMWRPPPLLQLDAGCPERGSKSVEKGVQEQRESETLSVNYLQIAYIPPSPAEPDPEPIREGTINTAAVLAALSAVATARSNANAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNW5</accession>
    <name>A0A9P6MNW5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_002830</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">In the C-terminal section; belongs to the trehalose phosphatase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">In the N-terminal section; belongs to the glycosyltransferase 20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001719">
        <property type="protein sequence ID" value="KAG0009010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNW5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005946">
        <property type="term" value="C:alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003825">
        <property type="term" value="F:alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004805">
        <property type="term" value="F:trehalose-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005992">
        <property type="term" value="P:trehalose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03788">
        <property type="entry name" value="GT20_TPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01627">
        <property type="entry name" value="HAD_TPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000052">
        <property type="entry name" value="Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000036">
        <property type="entry name" value="Alpha,alpha-trehalose-phosphate synthase subunit Tps2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001830">
        <property type="entry name" value="Glyco_trans_20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006379">
        <property type="entry name" value="HAD-SF_hydro_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003337">
        <property type="entry name" value="Trehalose_PPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01484">
        <property type="entry name" value="HAD-SF-IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00685">
        <property type="entry name" value="T6PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10788:SF15">
        <property type="entry name" value="TREHALOSE SYNTHASE COMPLEX REGULATORY SUBUNIT TPS3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10788">
        <property type="entry name" value="TREHALOSE-6-PHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00982">
        <property type="entry name" value="Glyco_transf_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02358">
        <property type="entry name" value="Trehalose_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0009010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="791" mass="89582" checksum="3797FB9CFD8C96BC" modified="2023-09-13" version="1">MKNPNVFPEVEPRPTLNQPRSRASGLPSVSTQKGQPHRRPSIDSAKVFADAAWTVEKASSGNIGLYNAVNSIQDQLAKTIWIGTLGMATDTLPDRTRGDIKAELALNHSSIPVFILWPTFHYVLPDNLRNKSYEDGSWKHYVAVNRAFADAIVENYRQNDTIWVNDYHLMLVPNMVRERLPDASIGFFLHIPFPSSEIFKCLHVRKEVLQGLLGADLIGFQTYSFVRHFLQTCSRILSVESSPKGIQLENTAVSVGIFPIGIDTKGLNVRRQDPEVAQWVNVLKEKYSGMKLIVARDKLDYVKGVRQKMLAFERFLDLYPEWQGKIVLIQVALSTTEQNEFQGQVSDVVTRINSRFSSLSYQPIVFLHQDITFSQYLGLLTVADLCLITSLRDGMNLTSHEYIVCQEQQKNPLVLSEFAGTYGSLGACLRVNPWNYAEVAEAIHEGLTMKDDEKAIRWNELRKHVCTNSAQFWASDFVSELVKVHGDLQRRYSIHIPLFNMGVVLPEFQAAKRRLLLLDYDGTLVPFERTTSVRSRSQTSSEDMMRIVKQLADDPKNVVYIMGGRTRESLDRTFGHLENIGLCAEGGCFLKFPGKSNWESQLQEGTDMPWRKKVMEVRKKEKSTTDDNECIQASNEMFEYYKERTPGSEIEVKTIPIVWHYRQADNPSYGLWQARECQNHIEEAIGSIYPIHAVVGRKFLEVMPRDINKASACKTIVESLQQQPGVEPIDFILSIGDDRSDEDMFAYCNGLDIGGENRVVTCTVGSKSSQARWFVPGVSSVLQGLQKMIGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPA0</accession>
    <name>A0A9P6MPA0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_003199</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001834">
        <property type="protein sequence ID" value="KAG0008659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPA0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0008659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="88" mass="9887" checksum="590B2258796DB91B" modified="2023-09-13" version="1" fragment="single">ECHKGTAQLWKLLQILWVRNTYHKRMTDGKVLQANHAQKTILIEALVETLTNATVCAVSFGDNVNFTKCVVGALDDDFVVLFKSYTMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPE2</accession>
    <name>A0A9P6MPE2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_003137</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001811">
        <property type="protein sequence ID" value="KAG0008714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPE2"/>
    <dbReference type="OrthoDB" id="655030at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46972:SF1">
        <property type="entry name" value="FAD DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46972">
        <property type="entry name" value="MONOOXYGENASE ASQM-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="9"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0008714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="397" mass="43910" checksum="560AEED88A8768A4" modified="2023-09-13" version="1">MSSSNSQLKIAIIGAGLGGLTLARTLQQNYINCSVFELDASPNSRPQGGSLDIHQESGQHALRTNGLWDKIEPHVRYEGEDLRIADKTGKIWLEEINEIDDPSYQGNRPEVDRGVLRQIYIDSIKEGTIHWGTQVKNIIPVEPLTENGRTLYTLVFRNGTEETFDIVVGADGAWSRVRALLSDAKPVYGGVIMIETRLMNVDEDYPEEAKLVGHGTMCALSDNKGIMVQRNGDGSIRNYVTLRIPENGLPEKEFLQESTGRAYLLNQFNDWCQDLRNLIENGQGLTPRPINALPIEHRWTSRPGITIIGDAAHLMSPFAGEGANLAMIDGLELGLVIVKVIKEGGDLAVCQQEFEKAMIDRSQQAAAMSAQNMKDFISADAPRRAVAFFQGHSQCEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPI4</accession>
    <name>A0A9P6MPI4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_002694</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001675">
        <property type="protein sequence ID" value="KAG0009146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPI4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000446">
        <property type="entry name" value="Zinc finger protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050329">
        <property type="entry name" value="GLI_C2H2-zinc-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048535">
        <property type="entry name" value="RRN6_beta-prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19818:SF139">
        <property type="entry name" value="PAIR-RULE PROTEIN ODD-PAIRED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19818">
        <property type="entry name" value="ZINC FINGER PROTEIN ZIC AND GLI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10214">
        <property type="entry name" value="Rrn6_beta-prop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="19"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="49"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="858"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1007"/>
            <end position="1041"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1084"/>
            <end position="1142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="863"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1012"/>
            <end position="1025"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1127"/>
            <end position="1142"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0009146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1142" mass="127345" checksum="5E259404A0A46B9B" modified="2023-09-13" version="1" fragment="single">MFDERLPTHERKHTGERPFKCGHPGCDKTFTQLGNLKTHEHIHDEVKPFMCRLAGCGKAFSQLGNLKTHTAKMHPDVNISDEELAVKTAASTSPITRAQASYSWRTTQEQRAGQVIAHFHPYQRRPVGPQWSERTQLLRDIQTMIQYQEQHALDATSESEIRFLESTFEGDRITDVPLLYDIIAESGYEDYKLSFYDPFIGNLCATGRFVDLPIVVTPGGRTGAELSISLVLHKPQLQPPFNFLAPKSTLLSFASAINQIATPSSGSPAAEQEEQILVRTKEAIAIVAPSDNVPPAISRVYHNYVRVLAQIPTSSSSNAPTDMDDDDMGEDITKSIGSSLRTSGSSNITIIKGEDKSSYDSKDPWRSCAWGAHPSQLAVASRNSLDLIDFRGAAIQTCLYTPRKRETICAIQEDKSLNLAPFQTYIATSHQIACIDQRFTKRPVISWTHQMDRAMPCGIKAMDLISEGSNYSTVLTWSKRNADIIAYNVSLGSNERKPSPMAMKGRAQELPSFQSHVQYTNTNSLRDPLKRYQYSAGPDQTLQQAIKPPLIGLAVLPDSVFDDDDDDGDDEIFDEVPTVKSSSVSKFSLVQYAYTGAVYAQEFEIRTEEEVKSDANNIRKNSILSADYNQGFGAIDGPSQNTLATSIAHDMIMNERLEEEEIIDSLLEAAEGRVAPWKRGVKEAQEQADDAIVNLAELHFHVDLDLQSLLAKLQKYMLVDREASTNSGLIDIDAKVEEAMDFINNSTFPLTMFEILEVIKCINAPSRERSVIAEMIQQNFELDPYATTEDGNITHRKIRKVWPITGRKIDTLIRDVEPNVDTITSYLEDLYPLPEVVLLEPDQVRMNEKAITSQLANLTIPESEQDEGLGMDETADQHSSSEGDVWPTQEIRLIRSRTIRRLAQDLLLANTVVIKTIEPEVSSAQSTTEYETFQYLFQNRDKNDGVSSEPKVRLPPKCKSVLDEWKIGESPFDYVYTLPEVAMNDVYISDDEDPDEVREHKERMIQLRQRRERREEKVRSARRNDPGYNVSAGGSLSQPAGVIAEPQSYSNAYGEADDDGMFSLPTVVSASQPASILRTSSLLRSQTQQKLNPKPIATPKNPVLGTSQPSIKSKKDGLSPIRSTFPSTSLASSLESTLVGSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPZ6</accession>
    <name>A0A9P6MPZ6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_002216</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001540">
        <property type="protein sequence ID" value="KAG0009626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPZ6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="37"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="370"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="40"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0009626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="729" mass="80248" checksum="8DCE2A7922088D05" modified="2023-09-13" version="1">MKSKTIHCNIVSFCWNDASQHQSALVATTDGQIWNIPLSHPTSPDPSINPSTTASSSIDHDPLNTPIKIEDSDEEVEEVELWNDEDGLLDSADVLDSLSPAKRPRIGSPPEIAASARGTINPPTKVKPIVHLVGQEDGVTKIVTALNGLLIFRRNKDLVLWSSQHGFRPGTPVAKTVIVDANRADTTCHVVNGESQQQIFYGTNLGEIYHSQPGKDEGAIEVQKLNTRMQGAISSLVTSPREGNTQAKVITAISSIGDIVTIGLEPSTKTSEHAIVKMTIGAPVRSAFLANDHVYFLTAESRILRAPYSSLDSGKTDDLELLDLPLLHAFVPVPYNTNSTEVCGFYGLNHEGQVLRFQADLSNIGRSKAASDARNNVSEAIRELDKLSERVRQLELESQSILSQSDNESVAHAQSSSYTPIKTTFSTFVQTVAARFNGQRRYFVRLTIESTLNIDWSKGWSVALNLSTNPKTCLHMSEPTSTQNSDVTSSLEGLSPQAPWTQDIEIDMQNFSLPLTITLGLQFDDFSKTSKDNKLRGYFPVESLDLDVIHFSEPVRDRVKQNPAYYTQALAALRDVRKSESDSGNLIERLPTSAHKQEREREECKECARVAIKPLVFDIDTTEIKVAQCLPALLGDGVSHDRVKTLVHSSNRASLSIPDECLPMIKPTRLIRKAPALTQCDASLVWLMLEVKESTGSVVQASIDIRGVDHTRVLAVYHALEKRIFELFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQV4</accession>
    <name>A0A9P6MQV4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001402</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001316">
        <property type="protein sequence ID" value="KAG0010532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQV4"/>
    <dbReference type="OrthoDB" id="2432222at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31639">
        <property type="entry name" value="F-BOX PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31639:SF256">
        <property type="entry name" value="OS07G0242900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="9"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0010532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="480" mass="54551" checksum="336C2EBE3BD65FF6" modified="2023-09-13" version="1">MSKINPLELPEITLRVAEFLDEKDLVRCVSVCKSWHQTLLRSIWKKVAAIDSVLFRIPQGLSDDSLMQHRDLVQELEINESFSRFYTTTYPELHTLTIVDDNPNRETLDRKAYPEELIAFNPSLVHLKVVRLGRNILAPFWTAVSGLSYLKTLTLQDVTMNDTCSLGAFWSACQNLERLCIHQSRISAEGFEISGDLIFHKIQVLELHLPKNVDQKKQLDMIRRCPNIEDLTWNVVGDEDNVLDLFAQDAARELWPKLEGLSLSHSITDETLALVISAIPKITKLDMCNSGFGPESFQALKRHFKTLVKLNLSKCPATTSAMLQEIMCSCPRLEELRGDCLNATQDVVGCLPWICVSLRVLEVCIKFDDHSEDLQPAVFDRISLLVHLRSLAIGSSGLWTTMAFQQALDLRLASGLGSLETLKNIRHFGFYNTTQKFSKVEIEWMIEKWKKLDRVDGIVSDNTKHNALRKMLKDNGIIIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MR67</accession>
    <name>A0A9P6MR67_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Zinc finger, matrin-type 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ZMAT2</name>
        <name evidence="7" type="ORF">BGZ80_002100</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001508">
        <property type="protein sequence ID" value="KAG0009749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MR67"/>
    <dbReference type="OrthoDB" id="30343at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003604">
        <property type="entry name" value="Matrin/U1-like-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040107">
        <property type="entry name" value="Snu23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022755">
        <property type="entry name" value="Znf_C2H2_jaz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45986">
        <property type="entry name" value="ZINC FINGER MATRIN-TYPE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45986:SF1">
        <property type="entry name" value="ZINC FINGER MATRIN-TYPE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12171">
        <property type="entry name" value="zf-C2H2_jaz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00451">
        <property type="entry name" value="ZnF_U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="U1-type" evidence="6">
        <location>
            <begin position="94"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="147"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="13"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="147"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0009749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="218" mass="24603" checksum="B563B70CC76B947C" modified="2023-09-13" version="1">MSSSQKKGAYGTVEKKKSGRWDMEEMERRAKERAQREKELREEDELRALGKSGKKKTKTAPTEEAIAAERSERLVLESAVGKTQVVQGGPAGRAPGFYCKVCDCVLKDSKAYMDHRNGRNHLKNMGVDTKAVREDVSDVIAKLESMKRKAEEPKKNKYDLDARLEEVKRQEDRERAEKRERKKQKKNEKKADDTLDDGGMDPAMAALMGFSGFGSSKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRN1</accession>
    <name>A0A9P6MRN1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">ATP synthase subunit beta</fullName>
            <ecNumber evidence="14">7.1.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">ATP2_1</name>
        <name evidence="16" type="ORF">BGZ80_001748</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Produces ATP from ADP in the presence of a proton gradient across the membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 14">
            <text>ATP + H2O + 4 H(+)(in) = ADP + phosphate + 5 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:57720"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="14">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) and CF(0) have multiple subunits.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.2" evidence="14"/>
    <dbReference type="EMBL" id="JAAAID010001402">
        <property type="protein sequence ID" value="KAG0010149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRN1"/>
    <dbReference type="OrthoDB" id="14523at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042776">
        <property type="term" value="P:proton motive force-driven mitochondrial ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18110">
        <property type="entry name" value="ATP-synt_F1_beta_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18115">
        <property type="entry name" value="ATP-synt_F1_beta_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01133">
        <property type="entry name" value="F1-ATPase_beta_CD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1140.10:FF:000001">
        <property type="entry name" value="ATP synthase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.170:FF:000004">
        <property type="entry name" value="ATP synthase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000026">
        <property type="entry name" value="ATP synthase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1140.10">
        <property type="entry name" value="Bovine Mitochondrial F1-atpase, Atp Synthase Beta Chain, Chain D, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01347">
        <property type="entry name" value="ATP_synth_beta_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055190">
        <property type="entry name" value="ATP-synt_VA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005722">
        <property type="entry name" value="ATP_synth_F1_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050053">
        <property type="entry name" value="ATPase_alpha/beta_chains"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036121">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024034">
        <property type="entry name" value="ATPase_F1/V1_b/a_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01039">
        <property type="entry name" value="atpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15184">
        <property type="entry name" value="ATP SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15184:SF71">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT BETA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22919">
        <property type="entry name" value="ATP-synt_VA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039072">
        <property type="entry name" value="ATPase_subunit_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47917">
        <property type="entry name" value="C-terminal domain of alpha and beta subunits of F1 ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50615">
        <property type="entry name" value="N-terminal domain of alpha and beta subunits of F1 ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 14" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="7 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11 14" id="KW-0139">CF(1)</keyword>
    <keyword evidence="6" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-1278">Translocase</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="15">
        <location>
            <begin position="180"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0010149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="511" mass="55002" checksum="AD10BFF565D99ACA" modified="2023-09-13" version="1">MYALRNISRLSKSAAAIKTAPKAINAAYMKKAGYASEAKSSGQIRSVIGAVVDVQFDQGKLPSILNALEVKNLDRRLVLEVAQHLGENTVRTIAMDGTEGLVRGQPVEDTGAPITIPVGPECLGRIINVIGEPIDERGPINAKQSAPIHCEAPEFVDQSVVPEVLVTGIKVVDLLAPYARGGKIGLFGGAGVGKTVFIQELINNIAKHHGGYSVFAGVGERTREGNDLYHEMMETGVIKLEGESKAALVFGQMNEPPGARARVALTGLTIAEYFRDQEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLSTDMGGMQERITTTKKGSITSVQAVYVPADDLTDPAPATTFAHLDATTVLSRGISELGIYPAVDPLDSKSRMLDPRIVGEEHYETASKTQQILQSYKSLQDIIAILGMDELSEEDKLTVERARKIQKFLSQPFTVAQVFTGSEGRLVKLEDTIRSFKEVLEGKHDHLPEAAFYMVGDIEDATAKAAKIAAEISGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRV6</accession>
    <name>A0A9P6MRV6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Putative lipoate-protein ligase A</fullName>
            <ecNumber evidence="5">6.3.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">AIM22</name>
        <name evidence="12" type="ORF">BGZ80_000978</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-lysyl-[lipoyl-carrier protein] + (R)-lipoate + ATP = N(6)-[(R)-lipoyl]-L-lysyl-[lipoyl-carrier protein] + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:49288"/>
            <dbReference type="Rhea" id="RHEA-COMP:10500"/>
            <dbReference type="Rhea" id="RHEA-COMP:10502"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.1.20"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein lipoylation via exogenous pathway; protein N(6)-(lipoyl)lysine from lipoate: step 1/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein lipoylation via exogenous pathway; protein N(6)-(lipoyl)lysine from lipoate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the LplA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.1.20" evidence="5"/>
    <dbReference type="EMBL" id="JAAAID010001216">
        <property type="protein sequence ID" value="KAG0011061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRV6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016979">
        <property type="term" value="F:lipoate-protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017118">
        <property type="term" value="F:lipoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009249">
        <property type="term" value="P:protein lipoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.50">
        <property type="entry name" value="CO dehydrogenase flavoprotein, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019491">
        <property type="entry name" value="Lipoate_protein_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004562">
        <property type="entry name" value="LipoylTrfase_LipoateP_Ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12561">
        <property type="entry name" value="LIPOATE-PROTEIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12561:SF3">
        <property type="entry name" value="LIPOYLTRANSFERASE 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10437">
        <property type="entry name" value="Lip_prot_lig_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21948">
        <property type="entry name" value="LplA-B_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82649">
        <property type="entry name" value="SufE/NifU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="11">
        <location>
            <begin position="1"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00015925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0011061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="268" mass="30442" checksum="FC79DDE643664C7A" modified="2023-09-13" version="1">MMPREVFDRRTNVELVCRALQELDIPAVVNERHDITLDGKKISLFDTYVSGSAFKLIQRRSYHHGTMLIDTDLSSLGQYLKVDRSNLVTKGVASVRSPVTRLRESSFTIDHLSFCEATRTEFLKRYAFDQWRQNLEGEPIIVDEALVQTIEGVKTIREDMKTWEWMFGQTPEFTYKLNSKFSWGAVDVTITSKEGLITHVDIDAKDETAEDGSMALTALAVGMEGQKYNEQGLDLAIQRVRDEAPEVFSPRGAAEKVKDVAGWLKEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MS26</accession>
    <name>A0A9P6MS26_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_001140</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001256">
        <property type="protein sequence ID" value="KAG0010843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MS26"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47679:SF2">
        <property type="entry name" value="C-TERMINAL OF ROC (COR) DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47679">
        <property type="entry name" value="PROTEIN TORNADO 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="31"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="139"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="34"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="65"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="81"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0010843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="971" mass="110348" checksum="1727A4681B3E345B" modified="2023-09-13" version="1">MTGDDFKDLIPLRIEHHPNATLEVILKSTEDTGDNTNNAYRDFTSKLNTTSPTEAESSNNPSQAGKDRSRMDTFQERSQHHINSPKNHTPSSSVGLIGRPATTALESQAPLESQPLVTDDQANQTTGIMTVMDQHFNNLKIEMQRIKALKTQLVQMQKNIRQVQHQVEEKQQEMTRTQKHLLGPLAAVENRTQSLLSKTYELHENSLPRLFIILPYPEKRQDTFGRLTSDQFRLFFLCECRKHTTTEGGDIPNEIHLSNHEGYHISKPTEFFEKFGSYILTVMQMFKYGITTASVVVQPLEKFSIIDGAEEIQKYIDLTEDTIGTMVDESISFLGQHQKRTVCSTGTTSSIGFDELEDLEYPDLSCLKSYLRIRERGCSLGNLYRIIRAESHVEWICTTHYRTIYREDVIHDLNRIVEVNRGYFLENLGSVCVIVTSRTLAGQLYDAMVKAQCVQELIISMTWQMTMDDLMIFTDAVTRANVKRLEIMGSPIQETAISAHDRNLRHNLFIRLACRGRIQSLYLGGIDDFSKRVSSSSWTISHRLRVFKYSPKITPEDRATKSFISGILDHFPGLAELQLKTSQVESLVELVADKLGLSQFSVVTDLEATCLHNSIATILGFSFKKKQILQAGTVSKSDYNAPTGRPRVNRGISHKDLKLVISFCEPEYFTKDLFSLHSKYDWPLGDLDVVATDLALYPMARFLDFLTEIKAPRHLSLTIKDTSFVSAMDLQYLERVVSRAQAVKKLSLSFKSLEIKAEQEKLKYLHGPIGRRLTKLVFEGNIPGPCIPALLTKDLLPMLKSFKAINMNPPDVASKDWTQYIVAMASRSLKSPDMPHSRALLPNVSSILSSESTTSTCSLREGTPLKKFKISSNQLQSKEWRTLIKALDFMTLESISFQKSNFSLKQLKVLIDYVPGDSEKLFAVSLQSLDLTWTDIKEEDYSVQELFARLKKKIPRIEIMYGNFEDPIYWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MS79</accession>
    <name>A0A9P6MS79_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribosomal RNA-processing protein 8</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Ribosomal RNA-processing protein 8</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">RRP8</name>
        <name evidence="15" type="ORF">BGZ80_000410</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the methyltransferase superfamily. RRP8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001083">
        <property type="protein sequence ID" value="KAG0011816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MS79"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016433">
        <property type="term" value="F:rRNA (adenine) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.2150:FF:000001">
        <property type="entry name" value="Ribosomal RNA-processing protein 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000068">
        <property type="entry name" value="Ribosomal RNA-processing protein 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2150">
        <property type="entry name" value="Ribosomal RNA-processing protein 8, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007823">
        <property type="entry name" value="RRP8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042036">
        <property type="entry name" value="RRP8_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12787">
        <property type="entry name" value="RIBOSOMAL RNA-PROCESSING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12787:SF0">
        <property type="entry name" value="RIBOSOMAL RNA-PROCESSING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05148">
        <property type="entry name" value="Methyltransf_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0678">Repressor</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="8" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="11" id="KW-0804">Transcription</keyword>
    <keyword evidence="10" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="90"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="137"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="233"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="598"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="47"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="159"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="254"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="282"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="317"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="343"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="365"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="643"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00076672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0011816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="643" mass="71155" checksum="56C89B1A878137C8" modified="2023-09-13" version="1" fragment="single">KFKKEPVFEKRPPSEPKLGWGWVPEPVPLKERASWNRSTKAIRKAKAEEEKAKKEKAIEEKKRTVSSISGPGAAVELLLQGSVDMTDIAGLGNKKNKTKDGNDIVMTEAGSATQEPKKRNKRLERKIKRAAYIAALESAASSNTDGASEESKSVPAVTEEPEETTNEASEEVEAEGGEPAKKTKKKKILQAPAPVHPELAKLTNKEKRLLKQFQKKQQQEGVDLAAKALPELLKPAPKKAQEEKPAATVATTSESKKDKKDKNKEKKATATTEIATEVPATQEKKKDAKTNKKADSEVSKKQQQLAKEREKLLEALNRTNSALAELQNSLGDGDEDESPMTKADVKSAVQDKKGKKDKKKEKAAESTPTPASAPAPVAAKATPTAPVAQQKQPKLTKLQEQMKKTLAGGKFRFLNEQLYTTTGEEAFELFQSKPELFDEYHEGFRSQVESWPQNPVDIFISELKKMPKDAVIADLGCGDAQISDELTKKKYKNVLSFDLVAKNERVTACDIAHLPLEDNSVDVAIFCLSLMGTDFLRFLKEAHRVLKPNGQLKIAEVISRFTDVDAFVSALKALGFELKHSDSSNKMFILFDFIKPDPKLANDKSKKSKKGNKKQKVEEETEDIDVEELDGSSLLKPCIYKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSN4</accession>
    <name>A0A9P6MSN4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Nucleoporin Nup120/160-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_000590</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001123">
        <property type="protein sequence ID" value="KAG0011573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="67716at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059141">
        <property type="entry name" value="Beta-prop_Nup120_160"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021717">
        <property type="entry name" value="Nucleoporin_Nup160"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056536">
        <property type="entry name" value="TPR_NUP160_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056535">
        <property type="entry name" value="TPR_NUP160_M"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21286">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP160"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21286:SF0">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP160"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11715">
        <property type="entry name" value="Beta-prop_Nup120_160"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23354">
        <property type="entry name" value="TPR_NUP160_120_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23347">
        <property type="entry name" value="TPR_Nup160_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Nucleoporin Nup120/160 beta-propeller" evidence="6">
        <location>
            <begin position="66"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="domain" description="NUP160 middle TPR" evidence="8">
        <location>
            <begin position="896"/>
            <end position="1141"/>
        </location>
    </feature>
    <feature type="domain" description="NUP160 C-terminal TPR" evidence="7">
        <location>
            <begin position="1198"/>
            <end position="1435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1162"/>
            <end position="1183"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="1397"/>
            <end position="1452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1170"/>
            <end position="1182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF11715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF23347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF23354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0011573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1466" mass="164069" checksum="78B279987B94723C" modified="2023-09-13" version="1">MAPVAPMWWFKEVPVQLDAFVDTQHSVIHSVPCPRQVQPYNLDDHPHQVFENQGGVFAFPNQYAKSVVWRTKDNATVLELISISGKENTLTRQISFQFHAPILPGLHIAALAPFGGISIALLTADSVLYKLHISALSHFLTKDLPEGYSSAAQIKWTTNATPLLFKYLGDRQAAVASTDGALFLIKTALLAEDTNRHGHAEIRVFDLHDDTHHLPRIQDVSAVQKIRSIFQTGSDNGRSFPTGFQDQKTRMDILAMESYTTHDDTLLFTLYQDRTIRVWSTGRRHCLQSMRSAPSPNDAGYVQETIDAASRAHLGIMFNPVMPWVLRLLVYIPTESDAQLIIYTSRIGTSDDIDFAQGPVSTIRPESAAGLGSTPSSLVKMDINLNSSQTGYTIWGLWETDMRISVKYMQIDDPAADREHYQQLATRDLLDGRWWPVAMQAPLSGFVKSMSAVDDSVENVSEYYAEFIFSSGRFSDRTIMRALTSLFQDRVFELDSDLQAHVIDAMSVTPAGSPTVDKEYKRHRQILNWTRFISHCAKLDHEASAPLGLSIAPDTGYMIVVKQDALSFLTACDDSEILYHTFQDKQFEIAQFIATPQSQLRSTYPRLQDPSLRSDVSKIFRAIDFLTRHLTVETSKNLEAIISQLSSSNGPRNFIDAFSQEHLPHFIPKTDMNRARNLVLSCKAPTDVFRFLNAQLLHNADSSSVGLSSHRCILPYEALVASSIQQLAANRYTMAQDFLILLAVSFSAAPSSRPWIQEETEFVSDALRVTQSLLVLKWISNQTVTSSSATSGLERQLSKMQVHDAPPVVPETIHRQSLTGSLLKTLSSETNKYGAVEFPIYLAIPRAVSKFLYGLGITNQGPDEDSKYHAGLAQRLSGRGSMLLLSRFLDIVPVTSSLSYYRGKVLLSQGKPALALEQFMAVAASFGNDVGSVEQELDIMQLDYATGVIRGHAKLEDYYNNVITLFAENDAHEQVVYVARLALSDLLQNARASVTESQIRALLERIIHAALAIGSYERAFNAMMLISSESLKRQILKKFVNKICENGDGAKLALFTFGGLQDDVERILKSNAEQGAVLSKPDHYKVLYAYYVYKGEYKKGAGIMCQYVRRLCDGTNRTESIWRLLTEAGSACLAAINALHLAGPHNAWISIPASDADVESDEPLKRRRLSSATNGSSFTLSTTDRRANTPHRVEIVQLLDLKQEFALIKAKLLLVTDIPAQVIPGAFTMTPRETQLLLVQCGNHEVATSLALLYDLDLDVVFKLLVDKYLCDLRLEQDELLGQGGLQGARSIHVDRSRSASSLQTLQSYLERHDDASSSYKYRLGMVENILTVNPDFDLPPWLSQHYLVHNPEDLIRLYLKFGALEKAAKFALVVIDAAMKKEELISRHSNARWLPYSLLDEIFEELNEQIQQAQDHVPNKKALTQTANAKDKKMERRVLELKDLKAQLDENMRLYLENVERESIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSU3</accession>
    <name>A0A9P6MSU3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">G2 m phase checkpoint control protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_011789</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000993">
        <property type="protein sequence ID" value="KAG0012375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSU3"/>
    <dbReference type="OrthoDB" id="21539at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033962">
        <property type="term" value="P:P-body assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034063">
        <property type="term" value="P:stress granule assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01736">
        <property type="entry name" value="LSm14_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025762">
        <property type="entry name" value="DFDF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019050">
        <property type="entry name" value="FDF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025761">
        <property type="entry name" value="FFD_box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025609">
        <property type="entry name" value="Lsm14-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025768">
        <property type="entry name" value="TFG_box"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13586">
        <property type="entry name" value="SCD6 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13586:SF0">
        <property type="entry name" value="TRAILER HITCH, ISOFORM H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09532">
        <property type="entry name" value="FDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12701">
        <property type="entry name" value="LSM14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01199">
        <property type="entry name" value="FDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01271">
        <property type="entry name" value="LSM14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51512">
        <property type="entry name" value="DFDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51513">
        <property type="entry name" value="FFD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51536">
        <property type="entry name" value="TFG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sm" evidence="7">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="DFDF" evidence="4">
        <location>
            <begin position="264"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="FFD box profile" evidence="5">
        <location>
            <begin position="317"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="TFG box profile" evidence="6">
        <location>
            <begin position="352"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="78"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="335"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="FFD box" evidence="1">
        <location>
            <begin position="317"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="TFG box" evidence="2">
        <location>
            <begin position="352"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="80"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="102"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="123"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="163"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="221"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="350"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="364"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="378"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="418"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0012375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="438" mass="48231" checksum="634FBC0380148ECE" modified="2023-09-13" version="1">MSGGYIGSKISLISRSDIRYVGILHHLNPTDSTVALEQVKSYGTEGRRGNPAEEIPPNDNIFEYIVFRGSDVKDLHVCEPPAPQPPARPQVPDDPAILGTTAPPNYYNQHQQAPPVGYYQPPLQQPQPQPQPQSQPQPQQPVQQQRRTQDQVEPKFSPAADGKAADKDANQLDKSDSETIKPAPPPARSAPKSQPQELRKSVEILAKQVSELNVSKDASEPVQNENENKFSNNRLPGMGGHLLHSNNNRRGGRGGRGGSHGHMNNTRAPAVPASDFDFETANAKFHKDELAKEVGKTDDTQAEVVEEEEVIIPQAEEFYDKSKSFFDNISCETKERMNKAEQSQGNRLSAPERRAKQSEERQLNLETFGQTSVDQGRFRGGYRGGYRGGYRGGPRGGGGYRGNYNNGGMGYNSGRGGHYNSNSSNSRGGYQHQQQYQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSU9</accession>
    <name>A0A9P6MSU9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_000830</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001182">
        <property type="protein sequence ID" value="KAG0011244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSU9"/>
    <dbReference type="OrthoDB" id="431169at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12245">
        <property type="entry name" value="RRM_scw1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000089">
        <property type="entry name" value="RNA binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10501">
        <property type="entry name" value="U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A/U2 SMALL NUCLEAR RIBONUCLEOPROTEIN B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="190"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="562"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="297"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="396"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="8"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="399"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0011244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="680" mass="72655" checksum="FFE39018CF5F50D5" modified="2023-09-13" version="1">MVIHSVDTTSSASSSSSSSPSHSPTTSSSPSLLSSPPSTATTTPLSHSSPTAKDLATVPDKSTSSTYSHSIFEDQDLTSVRAINILNDHHTNNQSTTDGISDPFGLSDYFSSSVPKAGLTNGHQSNSLHIGSLTSGLSGLSLAAQGLSSFGNNSNSKSSLSSGLYGYSNNSNGSLAFSNTPTINPAEEISTIFVVGFPDDMQEREFQNMFVFTPGFEAATLKIPHKDQQEDDALTLGVNGVNPRKQIIGFAKFRSHQEALQAISVLSGRRVDAEKGSLLKAEMAKKNLHTRRGLSNELVATPGPGVTSAAVPPTPIGSTSIHPVNINGKKTPHPLQHRNSLAGSAAYDAFHSVPCSPALPSDLLTPSDYASSYDFYADVYAPNNLSNLSFAESFGGRLQQQQQQQQQQSQQQSELSSSFLGRQSTFDMRVDPLSMGSFSNNIGGLSGSISGSFSNSISSSFTSRNIGFTGSQRFNKSFLDLDPETPTSTMSFLSKSIPAHTERGFNNGLFNSDDMSNNRFQGLPINTAAAAALATTSLPSPNVASPGFRTPINPGDQNPPCNTLYVGNLPMNTSEDELRTLFSRCIGYRRMCFRTKANGPMCFVEFENVECATQALNDLYGNPLSNSVKGGIRLSFSKNPLGVRNSQPSSLANQLHNMNNGTAPYLDRRDSMTAMFEQHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MT53</accession>
    <name>A0A9P6MT53_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_000333</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001067">
        <property type="protein sequence ID" value="KAG0011917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MT53"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0011917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="184" mass="20309" checksum="596424685CABB3F5" modified="2023-09-13" version="1">MEEEQETTVAEVEEDQEAHEDVEIVELQETKEEVSKSEASASNIPNCAVKTRMPIPVQFRGLSTASLAFKKQAAESAPAATKAVAVEIPETDSIASHIKIFGGANPTRSIGLKKLGVRDIVRKYKNVEEQSQDQIAHVVRGHNDSEPRGVCGVYSLSTASRQLLFTSRRKMCHEFGENDTKSYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MU74</accession>
    <name>A0A9P6MU74_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mid2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_011383</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000908">
        <property type="protein sequence ID" value="KAG0012972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MU74"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040338780" description="Mid2 domain-containing protein" evidence="3">
        <location>
            <begin position="24"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="262"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="354"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="174"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="223"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="363"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="394"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0012972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="405" mass="42527" checksum="763A556EC2C76BD3" modified="2023-09-13" version="1">MRISWAIQTVAVFCLVAAHPVLADNHAADNDLTFVSVQDGGHSGVYFYNNAAGVADGNDPHYGRIVARSDDNDNDNNNNNKNNHHDRPRPRPGPYRTHVPVHNKHHHGKNPYHGKGSHGKEHHHGKEHHHSKNPHHDKTTKKPTHKSTESHKPHKTTESHKHSSKTHKSHKPKATTSAVSTTTTTTTTTTTTTTTTTTTTTTTTATTATAAPAAETQNTDVGNSSSSNSNNVPTGPSAAVETTATTSSGQNSKMSGTTSSSVGTIAGAVVGSVALAGLLALGVYRQRERRRAAEESEGMNPEMDEAPRTAFRHESFMALVKDAAQGFYAPGTGSGPGPSPLGVSSAVAATSAGVGSGADELTRNNSVRSQGSQRSLHSRRSISGSVNGAMPPTSTSPPPLAYLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUD0</accession>
    <name>A0A9P6MUD0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_011294</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000894">
        <property type="protein sequence ID" value="KAG0013081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUD0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0013081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="243" mass="26720" checksum="F431945FAE81F34F" modified="2023-09-13" version="1">MELAGAPMDMSILEPDTKDPTSNLGGANQGNYDNASMGRGVVVPDSQDTCDMPSSHSSAQQSLGRKRTLRQRARPEPSMSFERLESRRNTLIAVGASKDVTALICDSPSAIRRHKSYEHVQINFAKFTEDNGCDSNASDPISIMNYLARGFYELGWATATVFNYRSKILRLYDNTDAISSYPGYSSFMGAVAATGVKMIRNIDIDLTPVYRHIIDLGGNRAMLMLGLVKKIEPASRDLYPHAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVB7</accession>
    <name>A0A9P6MVB7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transcription factor BYE1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">PHF3</name>
        <name evidence="11" type="ORF">BGZ80_010601</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Negative regulator of transcription elongation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the BYE1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000755">
        <property type="protein sequence ID" value="KAG0014172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVB7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001139">
        <property type="term" value="F:RNA polymerase II complex recruiting activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031440">
        <property type="term" value="P:regulation of mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031564">
        <property type="term" value="P:transcription antitermination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006362">
        <property type="term" value="P:transcription elongation by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15552">
        <property type="entry name" value="PHD_PHF3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21538">
        <property type="entry name" value="SPOC_TFIIS"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Transcription elongation factor S-II, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SPOC_C"/>
    </dbReference>
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        <property type="entry name" value="TFIIS_cen_dom"/>
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        <property type="entry name" value="TFIIS_cen_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
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        <property type="entry name" value="Znf_FYVE_PHD"/>
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        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11477:SF11">
        <property type="entry name" value="TRANSCRIPTION FACTOR BYE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11477">
        <property type="entry name" value="TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SPOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07500">
        <property type="entry name" value="TFIIS_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00510">
        <property type="entry name" value="TFS2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46942">
        <property type="entry name" value="Elongation factor TFIIS domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51321">
        <property type="entry name" value="TFIIS_CENTRAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="9">
        <location>
            <begin position="237"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="TFIIS central" evidence="10">
        <location>
            <begin position="404"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="19"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="136"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="370"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="542"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="618"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="871"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="980"/>
            <end position="1006"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="38"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="136"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="159"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="373"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="577"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="589"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="651"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="663"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="872"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="911"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="921"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="950"/>
            <end position="966"/>
        </location>
    </feature>
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        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011050"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00021616"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51321"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="KAG0014172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1006" mass="109035" checksum="99E45A6D8B5D06F4" modified="2023-09-13" version="1" fragment="single">MADSTPQPEYYLHLDLTEGELESQPHTDGGEAFLDFSEPSHEEAAHQDITEQDNQWQTSDVKTVLDETVSVAGESLANSAGEFGGLLGAQVVMDTNATHWDGPHQVYGSLMDMELNKLSPPEQVSGCITPDLIFPSSLQSSTPIEENSGQEKAEAALEQPQSTIPEHAITSSASTKQAPSGTSKKVTAIPPADIRRSTRARRQSSIAAQSEEYLLNAQGSAPSVAPVPVERVTRSKKVYCYCQKPDDGEVMIQCDNCRQWFHGACVDITDEIAELMGLKNEKFFCDPCTEKLKVRAKSHPGKGLRGSRLSDARDCALPTCLNEARATSDYCSEECAIKGIELEASQAVKKEHRPSAIVIPSAKALVSHSAKKLSSPVQPTSPLQPTSPLQLKSPSSPKPEQNPVRSTALKGLTESLMVAFDSKTEQKETDAEQASQLASMIEKELYMVTATPGQSGCGKDYKAKYRSLFFNLKDKNNESLRARVLSGELEPHELVRLTPEELANPELQSIAEEVRKRSIHDSVLTIEQEPFIKKTHKGDVSYIPGHSMSSMSAAPDIEPNGSKEQDAEPKTNLTKGTPEEKTVEEMIQEKQSSNKPTPAGSPTTEALDKLLARIQTNKRSGEDILNDALSGGKRQRQAETGQDGSSYLPREPSPYSPSPSPSGSPVIVSTTPPDSPPPFMLEEIERSLKNKAASSAKQVLPVWQGTVEMDQVAKVFTRAIQVGGSRVIPGRVSTNPTADMVAAGWTDILTKNVTIEGRIPVKAVETYIAQQRQSVTKEVLIVRFELNSAPTGSFEQRKAEFEKLFHYFHEKSRNGVVPNKARQVKDMYLVPVGANDPVPQYFQGLVENEALVHGREPRNDALFGVLVVNKASSHHHRHGHGHGHGHSPSHLKSSSSTHRHSSTANSRPYPAHHDRRDSKDSQSGGHTSVSHPAPARPQAPIVVQQHSAAPAPPAPVPPPMPVPIKPPGLEQLQGLVDQLFHSGKPPVPVPTASPNATQGLTPAAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVC0</accession>
    <name>A0A9P6MVC0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_010093</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000667">
        <property type="protein sequence ID" value="KAG0015028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="5428737at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="199"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="107"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0015028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="303" mass="32766" checksum="413FF1EFDDDD4F4F" modified="2023-09-13" version="1">MANQYYKKDIHKSIEGLLTGLYVYEYLLDTSTSGVILRYIVQDQILSLKTKAPTLRFALYVVLGTAFLGFIRHLYSPDRYAVVIDFIGNVVNAQGSTGGQPSGGTGTSTRTLHSRSAAAAARSTPHNSNSSSQSDTQHPGVNDGLMTPGEVSAASSSRTGTQVFSSQARAQASLPLFEYTPQSDSSGNDPAEGYYVDEEETRHSLDNSPPNRTRHSTVGQGSNSSEADSGDTSDNSDSDEDDPLGDDYEEVLEQETFVVQLHFRDMMSYLFSNQETFSFSRIGLPAGSAAVDAEAMRVQNLPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVR5</accession>
    <name>A0A9P6MVR5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein-serine/threonine kinase</fullName>
            <ecNumber evidence="7">2.7.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_010391</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the PDK/BCKDK protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.-" evidence="7"/>
    <dbReference type="EMBL" id="JAAAID010000718">
        <property type="protein sequence ID" value="KAG0014525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVR5"/>
    <dbReference type="OrthoDB" id="407390at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004740">
        <property type="term" value="F:pyruvate dehydrogenase (acetyl-transferring) kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010906">
        <property type="term" value="P:regulation of glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.20">
        <property type="entry name" value="Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036784">
        <property type="entry name" value="AK/P_DHK_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018955">
        <property type="entry name" value="BCDHK/PDK_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039028">
        <property type="entry name" value="BCKD/PDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11947:SF25">
        <property type="entry name" value="[PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING)] KINASE 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11947">
        <property type="entry name" value="PYRUVATE DEHYDROGENASE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10436">
        <property type="entry name" value="BCDHK_Adom3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69012">
        <property type="entry name" value="alpha-ketoacid dehydrogenase kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase N-terminal" evidence="9">
        <location>
            <begin position="191"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="127"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="508"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="9"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="128"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="549"/>
            <end position="571"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU366032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF10436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0014525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="654" mass="72559" checksum="070B78362921F97B" modified="2023-09-13" version="1">MSMPRLPQTLRSSGLRSASKPKSQPFVVTVGCCSGSTYSTLAFTGSTAATRTSLVGAARQTVASTSNSGYMTNALGQCRIAIRNKHQVNLNNKHYSQLATAAHSASPPPSSASNPLQLQHKSQPIHMSASTFPSNSRTATAASVTPESSPLFRMNNPASIVQQRQPRRRYSPQHFYQNRILDPYVNQAANPITLRQLVFFGRNMQEDKLLKSANYVRTELPVRLAHRIRDFQNLPFIVGTNPHIELVYDLYWQAFEKLSKVPEIKTLEENDAFCELIKALLNDHLVVIPQLALGIMECSKHIPPDEVDRFMNKMLRSRISRRVLAEQHISLTANYNSPNHMMTDRGYIGIIYTHCRPRDIVERTALLAAETCRQATGGLEPPIVMLDGNIDAEFSYIPDHIEYILYELLKNSMRFVMQNGIPDPKTGSLPPIQITVCEGTHDIVFRISDKGGGIPPDMEAHLWSYSQSPARFANFEKISKMAATVQEQLVSPSRSVNSGSDNEKITLEADSESEGIILPPPPPTNKSSSTDTPNLLLDRHAPPRVNKTSSTSASSSSSASSSFSTSSSQSQHPHQETVIDPSQRPAPSVKPGHLDPEVRQYKDKSMHLGIGLPMSRVYAEYWGGDLKVFTMHGYGTDAYARFCKFGNIYENFDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MW58</accession>
    <name>A0A9P6MW58_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_010244</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000694">
        <property type="protein sequence ID" value="KAG0014759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MW58"/>
    <dbReference type="OrthoDB" id="2354674at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="49"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="120"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0014759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="422" mass="46885" checksum="6A7044D54711E1C3" modified="2023-09-13" version="1">MQVQEPSYPLAARLSGSQPNLNSNAPRIPPRPDQTSSTYAVFDSPPPTQQSQQQQQLQSEQQPQQYQPPSSTGSSESMPFNQSNTYISQKPPSTSSSTPPSPLGPSAQRTSHRKITTGTSPLASSPLASEAIRPTRIKPKPEMPTTLPPESVCECFICHAASPYSQQPPPEIPVNQRQELLRLAPTCPSIHLFCLASRIPMSLPLDPTQKSPLTRSILDYFYSTWISDDTELRAPRIQCLNFIPIHPITASSFDRYLEGQNWNKRICRPLWHAADLRCKLGMEGMYRNCAQDKCSSCFIFNDGFEDTIAKEKYVHLSPNSSRAHDHFMTSRVSNANGSYDPDNKVRCMVLTFAALGLTYDVPPSNEKIKRPPKGMDVVRRQFEIQGGRDGNSNGLDNVTGEEYGVFAADALVPLVMVLYKVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXA0</accession>
    <name>A0A9P6MXA0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pyrroline-5-carboxylate reductase</fullName>
            <ecNumber evidence="5">1.5.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">PRO3</name>
        <name evidence="8" type="ORF">BGZ80_009292</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-proline + NADP(+) = (S)-1-pyrroline-5-carboxylate + NADPH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:14109"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17388"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="EC" id="1.5.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Amino-acid biosynthesis; L-proline biosynthesis; L-proline from L-glutamate 5-semialdehyde: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the pyrroline-5-carboxylate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.2" evidence="5"/>
    <dbReference type="EMBL" id="JAAAID010000541">
        <property type="protein sequence ID" value="KAG0016337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXA0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004735">
        <property type="term" value="F:pyrroline-5-carboxylate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3730.10:FF:000001">
        <property type="entry name" value="Pyrroline-5-carboxylate reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3730.10">
        <property type="entry name" value="ProC C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01925">
        <property type="entry name" value="P5C_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028939">
        <property type="entry name" value="P5C_Rdtase_cat_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053790">
        <property type="entry name" value="P5CR-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029036">
        <property type="entry name" value="P5CR_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000304">
        <property type="entry name" value="Pyrroline-COOH_reductase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00112">
        <property type="entry name" value="proC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11645">
        <property type="entry name" value="PYRROLINE-5-CARBOXYLATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11645:SF0">
        <property type="entry name" value="PYRROLINE-5-CARBOXYLATE REDUCTASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03807">
        <property type="entry name" value="F420_oxidored"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14748">
        <property type="entry name" value="P5CR_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000193">
        <property type="entry name" value="Pyrrol-5-carb_rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00521">
        <property type="entry name" value="P5CR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 4 5" id="KW-0521">NADP</keyword>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyrroline-5-carboxylate reductase catalytic N-terminal" evidence="6">
        <location>
            <begin position="8"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="Pyrroline-5-carboxylate reductase dimerisation" evidence="7">
        <location>
            <begin position="196"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="11"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>NADPH</name>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000193-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0016337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="305" mass="31615" checksum="33DFD730DEA700A8" modified="2023-09-13" version="1">MPLNRPTICVLGCGTMGIAIIRGTLDSIAGATSGQSDSSQSSQLVSEQEEQEDLLRPGGFIACVSHKDSAAKLSKTLGDQVKVLHGAAGNVQGVSEADVVLLCTKPQIAKAVLSAPGIREALKDKLLVSICAGVTIEQLQSWTTPTTIVIRAMPNTPCKIREGMTVLSCGPNTDIQSMAFTTKIFSTLGRCRTLDEKHLDAVTALAGSGPAFACVMLEALADGGVMMGLPRDVATELAAQVLQGAARMVLTTGAHPAAIKDSVTTPGGCTIAGLLTMEDGRIRSTLARTIQEATTVASTLGRDKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXB1</accession>
    <name>A0A9P6MXB1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cytochrome c oxidase subunit 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">COX4_1</name>
        <name evidence="4" type="ORF">BGZ80_009622</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000593">
        <property type="protein sequence ID" value="KAG0015806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXB1"/>
    <dbReference type="OrthoDB" id="10249250at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005740">
        <property type="term" value="C:mitochondrial envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045277">
        <property type="term" value="C:respiratory chain complex IV"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006123">
        <property type="term" value="P:mitochondrial electron transport, cytochrome c to oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00924">
        <property type="entry name" value="Cyt_c_Oxidase_Vb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.11.10">
        <property type="entry name" value="Cytochrome c oxidase, subunit Vb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002124">
        <property type="entry name" value="Cyt_c_oxidase_su5b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036972">
        <property type="entry name" value="Cyt_c_oxidase_su5b_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10122:SF0">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT 5B, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10122">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT 5B, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01215">
        <property type="entry name" value="COX5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57802">
        <property type="entry name" value="Rubredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51359">
        <property type="entry name" value="COX5B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="3">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR602124-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0015806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="157" mass="17333" checksum="657D9CB4DB8F55CB" modified="2023-09-13" version="1">MFALRSIRAPLARTTLRTTSVARFSALSVRLGGHHEVKVSQGPGAAPGAVATDLDQATGLERAELLGKMQGKDIFDLAPLEFSVRGTKANPTIIRSRDPVRYVGCTGVGEETHEVRWLLIDETHEFDRCDQCGNVYKWAAYEPDENFPAVEKGHHHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXJ4</accession>
    <name>A0A9P6MXJ4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">sphingomyelin phosphodiesterase</fullName>
            <ecNumber evidence="2">3.1.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_009230</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the neutral sphingomyelinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.12" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010000533">
        <property type="protein sequence ID" value="KAG0016437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXJ4"/>
    <dbReference type="OrthoDB" id="40902at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004767">
        <property type="term" value="F:sphingomyelin phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd09078">
        <property type="entry name" value="nSMase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038772">
        <property type="entry name" value="Sph/SMPD2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017766">
        <property type="entry name" value="Sphingomyelinase/PLipase_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03395">
        <property type="entry name" value="sphingomy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16320:SF23">
        <property type="entry name" value="SPHINGOMYELINASE C 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16320">
        <property type="entry name" value="SPHINGOMYELINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040275553" description="sphingomyelin phosphodiesterase" evidence="5">
        <location>
            <begin position="25"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="6">
        <location>
            <begin position="46"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0016437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="316" mass="35150" checksum="D262F2434362BADE" modified="2023-09-13" version="1">MKISTSLLPLALAAVATVPSFTAAKNVTLSVLTNNLYLMSKILYPNWGQDTRAQLIANSDYIKYHDVIVFEECWDSSPCGILRNGLQSQYPYQTPTVGSTKSGWDSTSGSYSSMIPENGGVVIMSKWPITQKRQFIYKDACGADWFSLKGFAYVEINYQGTNIHVFGTHTQSDDSACTSGQAAGDRASQLSSMRSYIDSLNIPSDELVIMAGDFNIDRNSAEYASTLTRLSANQAGTFDGFAYTWDPDTNEIAHYNYPNDPSQYIDFVFTDKKHKAVNSMVQTSLYVKSPEYTIQSVAYHEYSDHYPVQSIIEVDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXK3</accession>
    <name>A0A9P6MXK3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_009476</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000571">
        <property type="protein sequence ID" value="KAG0016043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXK3"/>
    <dbReference type="OrthoDB" id="630188at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040387998" evidence="2">
        <location>
            <begin position="27"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0016043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="511" mass="57665" checksum="D1253C0AC1AECB58" modified="2023-09-13" version="1">MPMPVPTARHVATFLFCVICIQLIFRFHEPIQDVFLHPSRLTNDDESTNGASSSHRVDHPNVPLDIPQLAILNKLAESIVDVEAHRTFAESGLKDIHGSSILGDAGQVKKMRDQIHCWTKHGSWVRDIEGNTTTKPAQWPARQHLGYQTFSQCDHRFTDGLNKLAQEGQGDYHLGEYDQKNGRWIVREAVKYRWVPDETICGPKPLQPSTKDEETTAPLGLGDDRSKYQPFHAEDFCEILKDRNLIIAGDITQYQLHDSILSAAGIPFVSHGELDCLDSLPHPLCPSNSSYLKYARNDFISVPWALNRGDDDFPSGATVEQQWATYDLMLKYKVVLLNKGLVWRSDNEFLTELVFTMKHLWKYYPGTMIIYRATHQISNCTVLKEQGEDEALATPDGLSSIVPGTTIQRPLTQAPERIWEKEDVLRMHRPTMADIARQNKMAKVIVEAAGGIFLDTEEMFAKRPDGRMGDGDCSRFCAPGPIDAYADLIYNTLRILPRDTNPADDVNEVLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MY04</accession>
    <name>A0A9P6MY04_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein CSN12 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">CSN12</name>
        <name evidence="4" type="ORF">BGZ80_008816</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CSN12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000491">
        <property type="protein sequence ID" value="KAG0016903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MY04"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070390">
        <property type="term" value="C:transcription export complex 2"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016973">
        <property type="term" value="P:poly(A)+ mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000973">
        <property type="term" value="P:post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000146">
        <property type="entry name" value="PCI domain-containing protein 2 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045114">
        <property type="entry name" value="Csn12-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12732:SF0">
        <property type="entry name" value="PCI DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12732">
        <property type="entry name" value="UNCHARACTERIZED PROTEASOME COMPONENT REGION PCI-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00753">
        <property type="entry name" value="PAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="3">
        <location>
            <begin position="31"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00025771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00073854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0016903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="222" mass="24878" checksum="64B84A9BB507BD23" modified="2023-09-13" version="1">MVISSQLTNGKKWLSLADLPELDKFPMAHQVSMRYYTGVLASFDEDFTKAEPDLQFALDHTPRRFHSQRRLILHYLIPARLLRGSLPAAKILDEFPELATLYGPLVKGIKTGNVQMFDEALSQGSDQLMAMGTYLTVEVSRGLAIRTLFKKVYTISGGSSKLEVKQFQAALAFVGVVADLDEVECILANMIYKKYIRGYLSQEKRVLVLSKGNPFPSLNSIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MY16</accession>
    <name>A0A9P6MY16_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Enhancer of rudimentary homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007651</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the E(R) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000396">
        <property type="protein sequence ID" value="KAG0018007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MY16"/>
    <dbReference type="OrthoDB" id="7887808at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2260.10">
        <property type="entry name" value="Enhancer of rudimentary"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035912">
        <property type="entry name" value="EHR_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000781">
        <property type="entry name" value="ERH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12373">
        <property type="entry name" value="ENHANCER OF RUDIMENTARY ERH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12373:SF0">
        <property type="entry name" value="ENHANCER OF RUDIMENTARY HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01133">
        <property type="entry name" value="ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143875">
        <property type="entry name" value="ERH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0018007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="72" mass="8592" checksum="5522612A12D61957" modified="2023-09-13" version="1">MDEVIKMYEEYLKNKYPHKERIEFDVNEVLEMVYNLPDCAALVFDAKTASYIPHDKSWIQKQVVVRAQSRAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYK5</accession>
    <name>A0A9P6MYK5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ESCRT-0 subunit protein hse1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">HSE1_1</name>
        <name evidence="5" type="ORF">BGZ80_007671</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000397">
        <property type="protein sequence ID" value="KAG0017997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050384">
        <property type="entry name" value="Endophilin_SH3RF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14167:SF116">
        <property type="entry name" value="CAP, ISOFORM AC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14167">
        <property type="entry name" value="SH3 DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="1035"/>
            <end position="1094"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="50"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="94"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="198"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="271"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="325"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="507"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="980"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1114"/>
            <end position="1141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1175"/>
            <end position="1263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1316"/>
            <end position="1341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="50"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="101"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="125"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="275"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="343"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="365"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="404"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="420"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="459"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="535"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="555"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="575"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="680"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="714"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="745"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="767"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="803"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="998"/>
            <end position="1013"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1124"/>
            <end position="1140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1180"/>
            <end position="1203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1239"/>
            <end position="1263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1316"/>
            <end position="1333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0017997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1364" mass="147842" checksum="73FB0E9796F355FA" modified="2023-09-13" version="1">MAQAACSHIFQSLQSHIIFLNDQGVITDDSLKVILSELCNVDLQVISASKVPSSGTPFHSQPLPQPRPLSIRHGNRASIDADLQMLDLPGRKSISAENFDDSSIPTQNHDSLSHQNISRQRDQAADSESDSEVETEADREYQERLLRQEQQLERTPDHHNVDIVTGELDNLVAASTTDDQDLDENSVAVLEEVDDDDVHSEVKTLDRSISVSSNPKPELPLSSDYLTTSSALETTSVVSSTRSDQGVVASNSDVPVVVATSASATDVTALPHLHQVSQRSEVQPDATSQDKQNEHFGSSATPASNNLEQYEHHNSITQPTVFEHNQHAQPATAEATASVTSPQQQQQQQQQQQQQQQQQQQQQQHYSPEQSHQSYQPAHPPPSRDASNLSITEMLEAMGSSKTAKNDKELPSSRHIHEMSASTANSADGKDSMTSVESGRRLENQPPSPPPKDEFTPVAHHQPATSTTAPPQPIPDNRTVVPGSSPFPDQVIPQHLAMPVQAYQLYQPKPYQPKPKPSVKVAPKNQQLPGQAQDVVSQVATPQPQAQTPVQSQPLAQSQVPTQIQSQSQALFQGQPPVSSQPQPQPQQQQQPLPQQQQQPLPQQQQQPLSQQQQQPLPQQQQQPLPQQQQQQQQQQYHIHQPFQSQEQLQQYQQQMYFQQQQQHPLPHPPIHTGPEVQNASSAGGPPSTTSTNDSAHKSGKGWMSAFRSSLLSKDSKKEGKEGKDSKHAHVTSHENVAPPQLQYGPPQSQFGPPQSQFGPSQGQFGVPTSQYGPPQPQHSQGQVQPSGSYNVGYTMNPVSGAPPTLQNQQQQQPIHQQQQPIQQQQQPIQQQQQPIQQQQQPIQQQQQPIHQQQQPVQQQQQQPIQQQQVYHQQQLAQQPYQAQQQPTQQQPPQQQPVIAQPSGQQVSGQQQQLQPPVSNVEVRQTEPVVAPAVQDKEMTSLNGAGVRHDNLDAASAAAAAIQAARHSTSTSPVVGYNAKADEPAAGPVTGPYQTATQPQQPMVQLPEQQQQPPGSPVSDAGSRVSVVSEVRNLPVIARAKALYDFAGEDEGDLPFKVGDVINVIEFLNADWWRGILRKDVGIFPTAYVQQEAPPANGQYPTISVSVRQSIIAPSPTDSSVDKQQQGSGPQPGQLQPQPSFRANYEPTTLAASSPSVTVPSSGAPFQPMAVALSNAKTEGSTPASGVGSGSTPASGVGSSSSFPAPPPPPVATGAGASVFTYFPGSGNQPPISPPPSLRSGSQGALYSQGPGQVSPVSSFTPSQVASSAAFTSGLGSSVNSFSPDQLQQMQFQQQQQLQQQQNDLFAGYGRQPSFQQQASYQLQQQPPVSVPSDLSGVIGSNSHMTTKQMAAAVKSKKKFGSKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYP4</accession>
    <name>A0A9P6MYP4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Leucine-rich repeat-containing protein 63</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">LRRC63</name>
        <name evidence="4" type="ORF">BGZ80_006789</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000337">
        <property type="protein sequence ID" value="KAG0018752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYP4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050216">
        <property type="entry name" value="LRR_domain-containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051:SF1">
        <property type="entry name" value="RAS SUPPRESSOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00364">
        <property type="entry name" value="LRR_BAC"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="173"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="262"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="423"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="742"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="173"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="275"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="292"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="430"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="747"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="776"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="787"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="832"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0018752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="832" mass="90964" checksum="86709874BCFDA4F3" modified="2023-09-13" version="1" fragment="single">MGSTVSREHAKLPFGYTHAHREDHTCTATASTSLASRRRQRLAHRLLLIKSSDSASITPLQTRRFRLTEDGGIVPTIGESAGIGFPSAPVLSQWSIEDADSEDADSEDAEIVSLSSILNQGPEFELQWHAVGQDYDEGFYSSNGINAIASGSGTRTTVISDAGQDYDSFVCHSRSNTPGSIDHSTCPRSPLEPPLQHPQSKTDRETETDPYVLSGLGSTSSATVNRDVTLEIVEGLEIEKAQDYTIITASAVAATALQLSSPTQSDDFKHNTPAGSNSISSGSGSSSGQDEETQKNDTYLERPRVYPTQHLQKYSFKAIRQDLTDSDEETDEEETLASDRCKMDIISALGIAEAPKDSQESIPFNFFNEEPTFHSIPDQFRPHMTTRRYTTDGSSRGHGTWMDHDYNGGAVHLPQGFFGTQEHRFVDTGDGSDEESDPDGDEGDGDEYLRTKRFYRRKGVGASIPGVSTATLGSNGHSLFNYPATISADEDVSHFSPIPFSELPSLTSIKLCSYGIVKLSSNIRLLTSATCFQVVPIEIGFLRNLTLLDLSRNSLTSLPDSIQFLTKLTDLKLSFNYIEFLPSTIGELTKLTSLCADNNRLTKIPSQIGQLKNLAILDLDENPIRALPVEIGQLRYLKRLRLDGCPLVKEFVHSPLNSPPTLLELAARVIVRHRVNVPRLLPSHLKTYLKTSQQCSFCSGPYFESSFKRGKMIERDDTVIPLEYTLCVPHWNTDMERIKLMFGPRPATSPPPPPPKVNHASSTNSSNSGAKKHTKSASTSKLTSLSNDLTPASSTMLPMVDQSSGSSTPLNWTGSASTLINSDDLLAETPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZ10</accession>
    <name>A0A9P6MZ10_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000426">
        <property type="protein sequence ID" value="KAG0017662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZ10"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0017662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="301" mass="33704" checksum="76C794F43F7DACD1" modified="2023-09-13" version="1">MDSSSTHRSTSLVTPSNKRLRCDNMSSDSEGDEVQLQNLEEKFTIIMGHESTAKLLLDLTVPFGVKFQNGKILEVLALPGEAKKLMADPIVSVWPLKRQTASEAELRHVLWSRKFRDLVDRDLSQYEYLSDDLCQRTFRKDGQEVAQKLAGALIQTETQVMLTLKVELNGRTQSEDPHSHGLAFPTWESYVVEATTYEDTRRILIGTATWSALVTSAIILTTGHVIVGPDNTTFQTSEKLIRAMGDQDGEDVIKVNSSMNGCLESFAKDVQEIIATLNQDCVRKEIEARIKVVTLALMSWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZ99</accession>
    <name>A0A9P6MZ99_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Wings apart-like protein C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005718</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000281">
        <property type="protein sequence ID" value="KAG0019510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZ99"/>
    <dbReference type="OrthoDB" id="78088at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039874">
        <property type="entry name" value="WAPL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22100">
        <property type="entry name" value="WINGS APART-LIKE PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22100:SF13">
        <property type="entry name" value="WINGS APART-LIKE PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040359097" description="Wings apart-like protein C-terminal domain-containing protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0019510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="306" mass="34367" checksum="703F5CF82F0EB76C" modified="2023-09-13" version="1">MNLMLHVLRLLINVTNGYEPCCENLNQSGSIQILIQNFIQFYSHCRNYNPEEANAEVQPVLSSEMQRASESSLLNTGLGMISQDTMETYIEGTNIDIDGPSTSSFPTIKIENDANGWYDILLLSIGLLINMLETNPERREQITRKAMSLDCKAIEDCFHKECRCEKSFDALERLVEIYNTEATISEMTEDHVLAAYLALLIGCIVGGDPESESRLYSKINGQTLVPMLELLTEFTAINQAVQEKHFGFEDDDQVIVTQTSQPSTDSDLLEDPKASSSISFKAEETQHSFLQIISVLQDIEKRFSLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N058</accession>
    <name>A0A9P6N058_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_004476</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000228">
        <property type="protein sequence ID" value="KAG0020275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N058"/>
    <dbReference type="OrthoDB" id="6415790at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008521">
        <property type="term" value="F:acetyl-CoA transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035348">
        <property type="term" value="P:acetyl-CoA transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000289">
        <property type="entry name" value="Acetyl-coenzyme A transporter 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024371">
        <property type="entry name" value="AcetylCoA_trans_1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004752">
        <property type="entry name" value="AmpG_permease/AT-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12778:SF9">
        <property type="entry name" value="ACETYL-COENZYME A TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12778">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 33 ACETYL-COA TRANSPORTER -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13000">
        <property type="entry name" value="Acatn"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="103"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="171"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="200"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="243"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="282"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="337"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="369"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="400"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="431"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="534"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="10"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="24"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="52"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="82"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0020275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="574" mass="63945" checksum="C728B34580162A30" modified="2023-09-13" version="1">MSKKSDAKASSDPSIDAIASDSKQSSTTNGRTTALYQDNYASNPDTMLTQKKRGDTLLRDDEREELMMAPLRDGMTADENVDGEKSPTEEKSATLSGADTWNFILLVILYLLQGVPVGLTFGSIPFLLKAKMSYSQIGIFSLAHYPYSMKFLWSPIVDAVYNKDVGRRKSWIVPIQLMTGLMFFWLGMNIEDWMAQDQIAVGTLTIVFFILIFFCATQDIAVDGWALTLLSKESLSFASTAQTIGLNTGYFLSFTVFLAFNSSEFSNKYFRTIPQEYGLVPLGGYLKFWALMYLAITLWLVFMKKEERAHIDEDDIGIKGVYEIILRIIKLPHMKSFMLVLLTAKIGFIANDAVTALKLLEKGFSKEDLALAVLIDFPFQIIFGYYAVRWSSGARPLKPWLWAFFAHLACCVVAMLLVYGFPADGVVTASYFYMVLITTVTTSFTSTVAFVSMGAFMTVIADPVIGGTYMTLLNTLSNFGGTWPRFFVLEAVDYFTVSNCSVVDSKGQDFSCAAEPGKSLCESLGGECTLQQDGYYLVSSMCVLIGGLLLIFYIAPTIRYLESLSPKKWKLDQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0H2</accession>
    <name>A0A9P6N0H2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 12">Ribonuclease H</fullName>
            <shortName evidence="12">RNase H</shortName>
            <ecNumber evidence="5 12">3.1.26.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BGZ80_004253</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 12">Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 12">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4 12">Belongs to the RNase H family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.4" evidence="5 12"/>
    <dbReference type="EMBL" id="JAAAID010000219">
        <property type="protein sequence ID" value="KAG0020402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0H2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043137">
        <property type="term" value="P:DNA replication, removal of RNA primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09280">
        <property type="entry name" value="RNase_HI_eukaryote_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.970.10:FF:000002">
        <property type="entry name" value="Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.970.10">
        <property type="entry name" value="Ribonuclease H1, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009027">
        <property type="entry name" value="Ribosomal_bL9/RNase_H1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050092">
        <property type="entry name" value="RNase_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017067">
        <property type="entry name" value="RNase_H1_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011320">
        <property type="entry name" value="RNase_H1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037056">
        <property type="entry name" value="RNase_H1_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002156">
        <property type="entry name" value="RNaseH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10642">
        <property type="entry name" value="RIBONUCLEASE H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10642:SF26">
        <property type="entry name" value="RIBONUCLEASE H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01693">
        <property type="entry name" value="Cauli_VI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00075">
        <property type="entry name" value="RNase_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036852">
        <property type="entry name" value="Ribonuclease_H1_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55658">
        <property type="entry name" value="L9 N-domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50879">
        <property type="entry name" value="RNASE_H_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="10 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11 12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 12" id="KW-0540">Nuclease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase H type-1" evidence="13">
        <location>
            <begin position="118"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR036852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0020402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="255" mass="27510" checksum="457AD77E074DBD59" modified="2023-09-13" version="1">MPKVSKPPAKGFYAVHIGKTKGVYFTWPECEKQIRGVVNAKFKKFDSLKEAEEFVKNGPKVFTKPVPKAAVSSTGRPSPYAAAAAARAGESSNSVARQEASSSGKDNYISVNGVRVAASDTIVIYTDGSSLSNGRVGSQAGLGVFFGVNDPRNAVYRALDAVGNDTAPIEIRTDSMYTINIITKWSDGWIKNNWRRGDGGKVQNRDIIEPLITKIKNRPGPIKWVHVKAHVGTFGNEMADKLANEGAVKPMPSTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0J6</accession>
    <name>A0A9P6N0J6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">10 kDa heat shock protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">HSP10_2</name>
        <name evidence="5" type="ORF">BGZ80_003866</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Eukaryotic CPN10 homolog which is essential for mitochondrial protein biogenesis, together with CPN60. Binds to CPN60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the GroES chaperonin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000205">
        <property type="protein sequence ID" value="KAG0020640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0J6"/>
    <dbReference type="OrthoDB" id="184876at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044183">
        <property type="term" value="F:protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00320">
        <property type="entry name" value="cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.33.40:FF:000002">
        <property type="entry name" value="10 kDa chaperonin, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.33.40">
        <property type="entry name" value="GroES chaperonin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00580">
        <property type="entry name" value="CH10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020818">
        <property type="entry name" value="Chaperonin_GroES"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037124">
        <property type="entry name" value="Chaperonin_GroES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10772">
        <property type="entry name" value="10 KDA HEAT SHOCK PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10772:SF0">
        <property type="entry name" value="10 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00166">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00297">
        <property type="entry name" value="CHAPERONIN10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00883">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0346">Stress response</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00056825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0020640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="104" mass="11498" checksum="9B038B6F9A0000E9" modified="2023-09-13" version="1">MAFRMPKLTKTIVPMMDRVLVQRIKPQEKTASGILIPEKAQETLNEGYVIAVGKGSVTKEGKVIPLELKEGDKVLLPPYGGSTVKVDSEEFLLFRDSEILAKVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0K8</accession>
    <name>A0A9P6N0K8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_005604</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000276">
        <property type="protein sequence ID" value="KAG0019563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0K8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039327">
        <property type="entry name" value="CON7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36167">
        <property type="entry name" value="C2H2 FINGER DOMAIN TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36167:SF3">
        <property type="entry name" value="C2H2 FINGER DOMAIN TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="4">
        <location>
            <begin position="136"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="38"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="256"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="181"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="53"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="259"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0019563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="298" mass="33893" checksum="650FAF213DE342E6" modified="2023-09-13" version="1">MGMGMGVPAGVSAVPSVQTGIVRSSPLVGYMDTMSLQHAQQLPPPPPPHSHGHQPSSQISPASSPYATSLIADPHSFTPPQEHQHLQQQQQQLGGTWLTEGDNGLNANKTYSFVPLSGVNTKKRPRRRFDEIERLYVCSWADCEKAYGTLNHLNAHVSMQKHGPKRHPTEFKELRKAWRRQKKAEEEAAKQAAAFQQQQQQQQQQQQQQQQQQQQQQQQQQQIQNQIQHQTQAPNQFQLCDPVLANMHAHPMTLHTMSHHQPQLPLHAHPNQHSHQHQYVQPQPQPQPQPHLHHPMGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0R2</accession>
    <name>A0A9P6N0R2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Potassium channel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BGZ80_005583</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000275">
        <property type="protein sequence ID" value="KAG0019585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0R2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015271">
        <property type="term" value="F:outward rectifier potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022841">
        <property type="term" value="F:potassium ion leak channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030322">
        <property type="term" value="P:stabilization of membrane potential"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003280">
        <property type="entry name" value="2pore_dom_K_chnl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013099">
        <property type="entry name" value="K_chnl_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11003:SF291">
        <property type="entry name" value="IP11374P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11003">
        <property type="entry name" value="POTASSIUM CHANNEL, SUBFAMILY K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07885">
        <property type="entry name" value="Ion_trans_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01333">
        <property type="entry name" value="2POREKCHANEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0407">Ion channel</keyword>
    <keyword evidence="5 8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="162"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="425"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="449"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="480"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="domain" description="Potassium channel" evidence="11">
        <location>
            <begin position="113"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="Potassium channel" evidence="11">
        <location>
            <begin position="432"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="200"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="273"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="568"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="681"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="897"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="959"/>
            <end position="1031"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="207"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="698"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="760"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="983"/>
            <end position="997"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1006"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1016"/>
            <end position="1031"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0019585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1031" mass="115683" checksum="903C28217CABDCA3" modified="2023-09-13" version="1">MVAVALIMAVICNLCVLSRFLERNIWHSVVLSLITATLQDVLSVGAIVPFCLMYRPSAGYYYLEGFWTMIASMIFSLTATAIMSIDFHCTPNFRLQGSGVTHKQRMLIAQAMALCFYLAFGALVMIWIEHWTFLDALFFGMITITTIGFGDTTAKTSGGRVFVVFYGAGGIILFAMAVNAIRYVILEDLHRQFAIRAKERKAKKDARKRERKEQRLIEQEQQRQHLRETLERMSSLENQSETNTVNGTGHLLHFPILHNLTLQRGSTILSLFSRSTSDSPESKSQDHSVPSSANELFAGVGGAKNEPKLLETLQRGTCENRKDVLCTATSGVDGMTDRPIEGNACLGTPRDSASEKDAKSLHSNEDIAVKGHKLSLVWLQFRRLCGLKTASPIEIAAPCQTLKEQREADRKLAYQESMEEYSRRLRLSFIMFMSFWLIGAGIFQVIESWSYGEAMYFCFVAFSSIGYGDVVPHTLAGRSIFLVYCLVGVGALTSLASLISEVISKTMRRHVVETQIRRNERFLRLGVLQRRASDTDLEQGYVVGGEEVAENEFSRDDGSRQQRAQNIHGIVSQDVPVGGDEGDTPSDQRACRGSLQNLVEVTRDFDSLLQKILGRDYQKTEGSLSSTSASAYDASHAKEQSIYDYLEKEEDEDSAYLPSISRDVTSTSTIQRQTINALGPLGRFRNIKPEGTYHGDSSPPSESRFNITAWPSSTPSSNSNIAADKLKPRPPGANSQLFAPSPERHRQQSQQRFDYPPRPSSAQGTSPSHYRSNDGSVTISAAHWQKLIECSATFRTLTDTCEETLKRFLAWEANEKKKSQRRRKSKNRRKRLMQDRKRRFFEFGGSFGAIDDGIEDEEELEEELDEWDEEGSIEEYDGANDETLDRHRQLIANALLGTERPTDYHQSGHSSRARRPSITTRPSYQARMGLIQKSNVRHIPIDVSTDDSSATVVPALADEHTQTNRQVHRRPHEKERAGPRGRSLGKIRARSRGRSTSRNREEVAASCSQNEQPTGRSRSTDSYTRSTSNPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1J6</accession>
    <name>A0A9P6N1J6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mid2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_004296</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000220">
        <property type="protein sequence ID" value="KAG0020390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1J6"/>
    <dbReference type="OrthoDB" id="2449255at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040176427" description="Mid2 domain-containing protein" evidence="3">
        <location>
            <begin position="23"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="169"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="51"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="136"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0020390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="253" mass="26763" checksum="C3655D0C31D740CA" modified="2023-09-13" version="1">MRISRLTLLTLIGALFLSSTLALHDKTFDVVANNNAFENKKRDLIGGLFNSQSSQGSPASAPASTSAPTQPTSNLGSPSTTSDPTNTSTTAQPLPSLISNILNPSPVANPTGTATTTAASMNPKRKPKSGTSSSADGVNNSNDNTDSNINGTSIYPANKSQDETQSSELAPGLIAVMIILVLAILAAVAFSCYKIRQSQRRRRESWSEDILKNHAGSVGYSKGAGYGMYVGDGGFGKEKPDLWRKNLDLFHRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3T4</accession>
    <name>A0A9P6N3T4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Senescence domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_010675</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000077">
        <property type="protein sequence ID" value="KAG0022987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3T4"/>
    <dbReference type="OrthoDB" id="20821at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009686">
        <property type="entry name" value="Senescence/spartin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045036">
        <property type="entry name" value="Spartin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21068">
        <property type="entry name" value="SPARTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21068:SF43">
        <property type="entry name" value="SPARTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06911">
        <property type="entry name" value="Senescence"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Senescence" evidence="2">
        <location>
            <begin position="223"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="460"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="463"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0022987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="500" mass="54031" checksum="C38E2180BBEDD977" modified="2023-09-13" version="1">MSSTPPTSTSPDEKIELPSTIEIVLIVPKATIYQSIAPTSEKKLIGSGELRVYSSILEDSTPSMESTASSAAPPTTFFTLENKETSLNASQSLITHPLMPRSSAQKVSDRVWRFTLPGDGHLELQLPEASEEDITSLEDILTDRIVYTNQHELRNKLALVDGVGEIYGVLDEEDVEMDDDDNISLSENQKSPVVVHAIEPSEEYQDKPLKLKVSVPSGDDMASYITSASQSFGDHMVKGATFVAGGIASSGAYINSRVPEIQKPLVISPIIKKSIRKVTKVSRVTLSVTTRVKSAILSTAFNTGYRALRYWTAKDDREEYSTMQNLCYSVLNSAGILIEATEQSVGIITEPVITATQNFAGRALGPDARDIVTDALEGFKNLYLVYFDSAGISRRAFLRTSRLAALRTAKEVKEGKIKLKERKKDSSNHAQETSISLTATAGAAVSHAKELVFKYVGKTDDNASGSSSPKVSSSSPKVSSSSPKASSSSSSSAQSEKKNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4P7</accession>
    <name>A0A9P6N4P7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_002422</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JAAAID010000016">
        <property type="protein sequence ID" value="KAG0024471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N4P7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005776">
        <property type="term" value="C:autophagosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000407">
        <property type="term" value="C:phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010506">
        <property type="term" value="P:regulation of autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045269">
        <property type="entry name" value="Atg1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24348:SF22">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24348">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE UNC-51-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="25"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0024471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="314" mass="34738" checksum="706AC7F492914B68" modified="2023-09-13" version="1">MMTPNPLQPQPPTKSLPYAIDNGSLIFQEMLGVGAYGSVYRALDTQSGEMRAVKCLSNSGLNSRQRAFQFNEVELHAMVSSHPNIATLHRVIEEDDCLYMVLDCGDDGDLFYAITERGGFVGNDVAIKTTFGQIADAVLHCHSRGVFHRDLKPENIILFPDSIKLVDFGLATSQLISTDFGCGSTFYLSPECQGGFNKTVKSYDSAANDVWSLGVILINLIFGRNPWKQACSRDETFLAYTNNNDFLLTILPMSDELHEIVKAVFCLDPRRRISLNEFARRVQACQSFTNFGRASDNSLPGKSQDSGIGFHSLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N6S9</accession>
    <name>A0A9P6N6S9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_002430</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000016">
        <property type="protein sequence ID" value="KAG0024479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N6S9"/>
    <dbReference type="OrthoDB" id="19657at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050471">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43433:SF5">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43433">
        <property type="entry name" value="HYDROLASE, ALPHA/BETA FOLD FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="38"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0024479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="312" mass="34370" checksum="CD4C48BF4697F60E" modified="2023-09-13" version="1">MTVLPHHEKGHIEVGHTRDKKKPFKLYYEKAGNGPKKLLLIMGLNSPGSAWEPVFEHFSNNPEYTTVFFDNRGVGHSDAPKGLYSTSQMAQDTIELLDALGWKSGVHVAGVSMGGMISLELVLADPARFSSLVLTSTNAGRSPPQLVTISFLTRVILIKDPDARIKLIMETLYPSHWLDSIPTTKGTLYKTNREAMVVSFKKRLEITPLQPLHGNIAQSWAALFHHVSSKRLAQIRSSGIPALVVTGTFDNFVRPSGSFHLAKELGCPLVVFEGSGHALPGEQTETYCRFIEELASKGKDGVFELAKKSYDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N7F1</accession>
    <name>A0A9P6N7F1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NAD(P)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_007715</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000004">
        <property type="protein sequence ID" value="KAG0024780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N7F1"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05327">
        <property type="entry name" value="retinol-DH_like_SDR_c_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF282">
        <property type="entry name" value="WW DOMAIN-CONTAINING OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0024780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="328" mass="36619" checksum="664F04DB864CD1F1" modified="2023-09-13" version="1">MNNSFSQLRFWKTFFTPNRYSHDQIPDLTGKVAIVTGANTGLGYCTTVALATHGAHVFLACRSQQRATDAIERVKAEIKEKYPQAADPKLDFLELDLNDMRKTRDAAKNFLVKGLPLHILVCNSGIMATPFELSADGIETQFAVNHMGHFVFTMELLDRIKESQPSRIVIVSSNGHELTAPGGIDFDTLNDETKTNTIQRYARSKLANILFTKALARRLENERVYVNAVHPGYVLTELARHVGASFGVILKQVLGVMNIVVAMKPEVGCLTQLYAATSTEIEEGDIRGKYFIPIANEILPNEYARDEELQEKLWTFSEKLVNEKIGGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N7G1</accession>
    <name>A0A9P6N7G1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Trafficking protein particle complex 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">TRAPPC8</name>
        <name evidence="4" type="ORF">BGZ80_003712</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000002">
        <property type="protein sequence ID" value="KAG0024853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990072">
        <property type="term" value="C:TRAPPIII protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058541">
        <property type="entry name" value="Ig_TPPC8_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058538">
        <property type="entry name" value="Ig_TPPC8_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057651">
        <property type="entry name" value="Ig_TPPC8_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024420">
        <property type="entry name" value="TRAPP_III_complex_Trs85"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12975:SF6">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12975">
        <property type="entry name" value="TRANSPORT PROTEIN TRAPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24545">
        <property type="entry name" value="Ig_TPPC8_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24544">
        <property type="entry name" value="Ig_TPPC8_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24542">
        <property type="entry name" value="Ig_TPPC8_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12739">
        <property type="entry name" value="TRAPPC-Trs85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TPPC8 first Ig-like" evidence="3">
        <location>
            <begin position="674"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="domain" description="TPPC8 second Ig-like" evidence="2">
        <location>
            <begin position="845"/>
            <end position="962"/>
        </location>
    </feature>
    <feature type="domain" description="TPPC8 C-terminal Ig-like" evidence="1">
        <location>
            <begin position="1227"/>
            <end position="1351"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0024853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1416" mass="158454" checksum="984A3F683318767C" modified="2023-09-13" version="1">MATSQMRTKDISARELVLKVMSPRIAVIASQGATELCQANHLPSVVDLLKPFGEHIEGRVMVHGSMGLPSAIDNFTLRFTEMDQLEEPDSKTTQKWLAEVVRATAIDYTSPFKIQSKENVTLEYLNAPTERVFPWYSRYRDLFFWTGGVSDHETFDHPVACIIAISSLTPDPINEIHELNKMSTPPLVFEKAYMDPALLKYYVLLHDCSRGNLDSAMEVLERMRRTFGLNCSILKINSVDPSQSTLPKDRNVNIWTKSVAMSKLLSIGHTAKDSASTRSSLSSISSTNASGTLIDLASQRSAMSSPVYSTTGNGSPTFAHTPVYTQLGNDDDDRTLDQEPLLLPPTENQGLTSDLLLHPEKIAEPYGCCLSEEDISGITQFIREMLSQSIIPYMERNIAHWNDQVAASRKGIAGRFKRYFGTSNRNPATALQQSPSAGPNGGLIYPHASPEAQMRKLADWAFMLRDYKFALSIYETVKKDFAADKAWKYYGGAQSSDLRNGLFLEQAACCYLRLPRPQVRKYAFHMIMAGHRFSKAEQREHAYRCYMAANDVYESKGWGLVDDHIGCALGRQSFHLGKSEEVLDHYKKLLRESRQSPQQQAVYMKEFLSVYRDYTNKIEADPLRETFPDFPLPVVLGSTARIVLSSSQSMNENNGAWAELEGGMQNSSSSSGGRTVSAVGEHVLATVDIKNPLQIPLILTDIVLGCEHSTSNTTFTVPMEAAEEAHLRLYDQQSPDFEGKVSFSAFTCGRIDRIILEPGQVRTLTFEVLPKLEGQIRVMGLHCNVEGQVHAYKDIVKKGKRLNKTKEQMMSQVYEEDKSLIILVAPEMPLLEVDFNSSPEMLLSGEVCELSLEIKNRGKKGLRNLTVRMSHPTFFCIGEKRIDGDLGLYDKGESNTATETVQVDNSLQSNTTQKILETVLAPGESIKIPSWMRGEKIGKHNFLFVFSYESEQEGTAMGVRTLRHTVTAQVLPSLKINAFTRPSTKGLNEFILGIETENLQTVPIFEFLQISSMSASWVIEAVGKSNDSEENRFIAPRQTVFTYYRIRKGSNVSTPAITPERFMAKALEKLVIGQEKLKDVPPPLDLQHCHLSTTESHINSSSPVLRHFSRASRLGWRQGSLKTQFSSIPANIDRRNLFSVYGSNDIDLALFWNIPKMNRRGHHYIIGINLGVQQNPFQPIDPADELDGEGEETETARRALYEQTMRDQAALVQALTMNPHFRDESPVKISMRSEDSVQHDFAQKRLCSTPVKVVIKNCSWNKHIAYTLEMLSSKDPMVPQKAPGSIDNSSQGAAAILDSTNPHMNARPFFWSGPTFSTGYLEPLAEVEIVYLASFTDYGVYDINRWRLAVQVVKAQRKKKGLNGAGNKKQHEDNILKTAEEDAEEEQRALMPAAAPEAVGKGFMQMPNLAHYIQVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SRW9</accession>
    <name>A0A9P6SRW9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">F-BAR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_007647</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003952">
        <property type="protein sequence ID" value="KAF9994955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SRW9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031982">
        <property type="term" value="C:vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030041">
        <property type="term" value="P:actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016050">
        <property type="term" value="P:vesicle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031160">
        <property type="entry name" value="F_BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054713">
        <property type="entry name" value="GMIP/FCHO2-like_FCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23065:SF7">
        <property type="entry name" value="NOSTRIN, ISOFORM H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23065">
        <property type="entry name" value="PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22699">
        <property type="entry name" value="GMIP-like_FCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51741">
        <property type="entry name" value="F_BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6 7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-BAR" evidence="8">
        <location>
            <begin position="1"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="119"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9994955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="293" mass="33954" checksum="05BD63DCA2441B7D" modified="2023-09-13" version="1" fragment="single">YAAKATPVAKSAAPYQEYLMDLISFMKKRSVMEAEYGTNILKLATGLRDNYRQQPDGANGQAHFKQGTYGDCWTHILEMHERLGNNRLEFSRDLQVVSEELSSIYKETDRSRKQFKEAGAKQERIVQEHEQNLEKAKQKYDTLTEEWERAILQKAADPTASKKTMTKGMSIFRQPKSVNQLQRQEEEARAKASSAHEQYKTQLAKTNDTRQYYFSHTLPSMLKNLKDTIDESDLSLQYYLMRYGYMYEDYMMKDAVILNPINSDLGMRDRVEMVNKDADLQVFVQAYAAKATP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SSU1</accession>
    <name>A0A9P6SSU1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007095</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003577">
        <property type="protein sequence ID" value="KAF9997041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SSU1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9997041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="350" mass="39248" checksum="7F3E3D9D1F368E4A" modified="2023-09-13" version="1" fragment="single">GRDACWVRWANGGCIKSMASPSYTGATDSLPEGIESAPYFKTTKVAEWSLQGFLTATGKDEKSFLSEILDLSKFKPVPLDVRLFAKGLYNFYNGIFGEEVTAIAKDQAQSSINRSVFRGKEQLIVQRRYKDDLENDLNRGVGSATQSKRAKPASELPNIFQNKNNLPNPFVEEEVSSSPSTWTLSSRLKGNRTAAGAKKKLDIAETSEENVQSPELFVDTEDVENDEMAQFESNTNDDAYSEDHTMYNVSANDKEASLVHFKMLNQDTEWVYEGMDMAKKFHEFRSRNCQSFSFARDWIADLTPGSQFEQALPSHIKPVANLVELSTINVSEGPYWQLYSGEFSHQTATT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6STP4</accession>
    <name>A0A9P6STP4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_006206</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JAAAID010003054">
        <property type="protein sequence ID" value="KAG0001290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6STP4"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019819">
        <property type="entry name" value="Carboxylesterase_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00941">
        <property type="entry name" value="CARBOXYLESTERASE_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040547371" description="Carboxylic ester hydrolase" evidence="3">
        <location>
            <begin position="20"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="167"/>
            <end position="660"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0001290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="684" mass="73317" checksum="49E4FCA42D7DB1ED" modified="2023-09-13" version="1">MIFAIFCLMAAASLQTVFAQVLIAPETDMNSTVVSNNIRPSASNPNILNSVRVLVDNNLEVHGAQFPFIYLPDQRLAFGGAASCGKLGERLYSAQSSSLPSVQKMLTRVAPSVTEFWIDTGAGDSRYLTACDTLVLKDGQAAIKTGGSCMRLLSSLCSNTNTSGKITVQAALGRITGARDAKGFRFQGIRYALPPTDNLRFAAPVPVTTRWSNAVDATAPGNKCPQLGEFPGGNEDCLFLNVFTPALSADKKNLLPVMFWFHGGAFVFGSGSDPTFNGANMASRGQVVIVTLNFRLGLLGFFERVDAGISRSTLPGNQGLRDILVALKWVQDNIASFGGDKTKVTIFGTSSGATTVRTLLSMPTITKDLFHAAISLSDVIHLPFNSVKAASTTISGGAMELLKCSDLACMRSKSVDEILNAQQIITGGAIEHSPEQSYIELIKPSIDGILLFNNFDQLLAGKGDFNRVPFMIGTMGGEAFEFLPIMGQVDIMPEAIFGATLMTLLGYRRTMITVGGKAYPFDLSNLDHTREATGLFATDYIFVCPAQFISKAYAATNTPIYHFQFQRGYSPNRPASDLCVTRPCHSDSLAIIFASPPLMGNATSSPWTAADAALSRTVIDRWTAFAISGNPNIPGDSSSPVWPQYDGTTQSVFMIDTTSSVSTGGIHPSGCGFLDQYIGYDFQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6STT8</accession>
    <name>A0A9P6STT8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006324</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003115">
        <property type="protein sequence ID" value="KAG0000654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6STT8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="447"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0000654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="509" mass="57044" checksum="728DE04C01AE085D" modified="2023-09-13" version="1" fragment="single">MTASRNATKELVVLRANSHVRGLVFIQRARKGASNPVYPATNHALGNAFTRGNANYLAEFPVAAYHYCVECTNSTTVNSITDSLYGVSLGNKDINMGPIMVLQCGHTLHMSHLDNLMQLSSYYTAQVDTESGKSTFVGCNRLPVKEDTPVACPHCRQPITGLLRYGRRLKNVELLKEIDAFQGSQVNGMKQTIQTFEAGLKLMARECALFLKSLSDTTVNANSCMIPPKSQMRPLGRFGSHEAQFRAKSFTMISQFYDIPKKQEREWRKFVAPIVHLPQQFTAIHQRACRSSVKQTYDAAIEQIYGKPASLGRRSESNVQRVSEKSAGIVDALDAAHLYVEGCGLPHKGFVGSSYVDSLLERTNVVMLIVSYAFSALQTVGAASGWYWFVEDLIRCAFTHIEALGRAAYRVGDKETLAYATVMRMDVVCRLMQWLVLRKNFRGHFGGEKLAEKLDEFQKEFQKLKKELEGNCADSVRTKCTIRVARLEEKVKRVVESMKTDTLEEILFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SUI1</accession>
    <name>A0A9P6SUI1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005547</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002731">
        <property type="protein sequence ID" value="KAG0004845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SUI1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="185"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0004845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="282" mass="31069" checksum="BFB81A8A3F6CD72F" modified="2023-09-13" version="1">MVSRLSPEHFRRVTSPMFNEDIELIHAMESSITKAGNETFFFNEFKYGNTTFDALVCMSAKSGEAGLMAICSYNSVSAIITGPQDFSPIISAARKGAPFEGPPIEVDASSDSNYTSTTVMTISHIPTVTNTTTQQLSIPGAKNASLASALYLASLGQNMYLYWNTSKLYVIYNIVDIERGLEMPLCLSIVVLVAMILCAGFCCLTHYFLDPIFTGSLYEVMSIQMAPKSNCFVAMIGWSKDHSTDCDGFHTTLNDNSFYDVDLMSEPWMTRSRSSKQATPIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SUP5</accession>
    <name>A0A9P6SUP5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Conserved oligomeric Golgi complex subunit 3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Component of oligomeric Golgi complex 3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">COG3</name>
        <name evidence="12" type="ORF">BGZ80_005426</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COG3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002677">
        <property type="protein sequence ID" value="KAG0005555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SUP5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005801">
        <property type="term" value="C:cis-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017119">
        <property type="term" value="C:Golgi transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048685">
        <property type="entry name" value="COG3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048320">
        <property type="entry name" value="COG3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007265">
        <property type="entry name" value="COG_su3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13302">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13302:SF8">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20671">
        <property type="entry name" value="COG3_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04136">
        <property type="entry name" value="COG3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Conserved oligomeric Golgi complex subunit 3 N-terminal" evidence="10">
        <location>
            <begin position="155"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="Conserved oligomeric Golgi complex subunit 3 C-terminal" evidence="11">
        <location>
            <begin position="324"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="Conserved oligomeric Golgi complex subunit 3 C-terminal" evidence="11">
        <location>
            <begin position="389"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="54"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="503"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="64"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="515"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF20671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0005555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="870" mass="98751" checksum="D1311F92CEBB5082" modified="2023-09-13" version="1" fragment="single">MSVPGRPAQHRTLDWDAIAPLSDLQRQSVLELKEACSELPLPANLSAEYSSPLSYSKAGGDLSPQLNAGANQSHHTSSPSLQPVGLLSPKSHGVKEFGSLPRSRLGSIPSIEGVNVEDYESEKLEPIETTQQFLDWFSGIEGEMERDQEDVYRNYLTVVVLYKEACDGFLKQIDETTECFKSLEGHYAFVEEKTRALQQACEKLLLEQTNLQTLADLMASKLSYFHQLEAVTRLFNSPGDDVCLRTEFIPMLSKLDECLDYVQQNLKYRDSELYQMRFRQCMTRGMTLIKMHLITKLRALSAEVASKKPVLAKGESIKPAMATALFYVKFRAIAPPLRSLVAELEKRCVSHKEYNSLLNDCYNCYFSVRQQHLASMIVSKIQEMGPSQQDKLNGYLDTLIGYLYDYLRPRIIHENKIDILSELCVVMNIQQSDIPIDENSHLAFGHLIRNMLHDAQHRLVYRAQAFIRSEIQGYKPTPNVLDYPARLQVSPPFPAGAENLSRTASSQHIHRPSDAESIAESIPEISSPTPSLASSVTGGYFSSPTIQQFDETSTMYQGWYPTLQKTLWLLTKIYKCVEQTVFDDLSQEALSKCLISLNQAAVAIRDTKDPVDGRLFLIKHLLILKEQIAPFEGNFVHLTKEVDFTRMTDAITTLFRDRTNLLSFGSWFGAVSQTITPTLVDSYLDARQEIDRDLKLVCETFILEMGKSAVHSLTEFMNKVAGFRIRADVEAAQREQDPSVSSGLTKRAPMLLKDRPFANPDELARIMMDFKDKVPPRIQWTVRKLSTYLRDPNTEMILMRPIQSFIIESYQSFYDTILYEYDPALTLKASQQPNGFRNIQHAGIRDLEPVEKIVPWVCDLVRAELKKNNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SVD6</accession>
    <name>A0A9P6SVD6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Clathrin/coatomer adaptor adaptin-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_005295</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the adaptor complexes large subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002617">
        <property type="protein sequence ID" value="KAG0006434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SVD6"/>
    <dbReference type="OrthoDB" id="10254310at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030117">
        <property type="term" value="C:membrane coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026739">
        <property type="entry name" value="AP_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11134">
        <property type="entry name" value="ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Clathrin/coatomer adaptor adaptin-like N-terminal" evidence="6">
        <location>
            <begin position="11"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0006434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="215" mass="24387" checksum="6D8802B2BDB264D3" modified="2023-09-13" version="1" fragment="single">MSDAKFFQRGKIQELRLELNSDKKDRNYTRKKATLKKIVANMTMGNDMSSLYPDVIACMSIPVLEVKKMVYLFLINYAKGKPEMALDAINTFRRDVEDPNPLIRALAIRTMGYIHVDKVTSCLIQPLRHCMRDQDPYVRKTAAICVAKLFMQDRHLVENAGFIDLTREMLVDSNPSVVANAVAALTEMSERSDHIQLKLNMSIASKLVTALNECS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SVY0</accession>
    <name>A0A9P6SVY0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Adenosylhomocysteinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_004399</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002245">
        <property type="protein sequence ID" value="KAG0007655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SVY0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004013">
        <property type="term" value="F:adenosylhomocysteinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033353">
        <property type="term" value="P:S-adenosylmethionine cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1480">
        <property type="entry name" value="Adenosylhomocysteinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042172">
        <property type="entry name" value="Adenosylhomocyst_ase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000043">
        <property type="entry name" value="Adenosylhomocysteinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23420">
        <property type="entry name" value="ADENOSYLHOMOCYSTEINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23420:SF0">
        <property type="entry name" value="ADENOSYLHOMOCYSTEINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05221">
        <property type="entry name" value="AdoHcyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0007655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="69" mass="7456" checksum="F3B1EDF050425C01" modified="2023-09-13" version="1" fragment="single">MTYKVADISLAAFGRKEIELAENEMPGLIALRQKYGPQQILKGARIAGSLHMTIQTAVLIETLTALGAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SW11</accession>
    <name>A0A9P6SW11_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_004243</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002186">
        <property type="protein sequence ID" value="KAG0007770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SW11"/>
    <dbReference type="OrthoDB" id="429813at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0007770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="228" mass="24897" checksum="2B905439CC93A2B4" modified="2023-09-13" version="1">MLSTIQPDHPHNFMVPPCASMRQWDFNHLPLAEQLQALGDDATPPSFSSVYFLKKWARELPDAPCLLVPNATATDYITFSYAQYDSATDIIARYWASKLNPSWLDADRTRAMAALDAPVALLVKDLPTSHFLIIAFHKLRIPVLLISTRNSPAGVSHLVTTGKVSAILVEDSLRSMLEPQIAHTPTYSVVPVNPDELLQAPAVPPVPHCADVDAQDIAIIVHSSGTTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWM2</accession>
    <name>A0A9P6SWM2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_003453</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001914">
        <property type="protein sequence ID" value="KAG0008430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWM2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040227168" evidence="2">
        <location>
            <begin position="28"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0008430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="94" mass="10277" checksum="62D6EF15E566BEA0" modified="2023-09-13" version="1" fragment="single">MTAIAKTTLFALAAALALALLATTTLTSQVRWTNALGKCYGWARKFPYKSKVAFGDLDSADPNRHYQQDPKDFTSCSDGKHGREPGADETRQNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SX95</accession>
    <name>A0A9P6SX95_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">rhizopuspepsin</fullName>
            <ecNumber evidence="3">3.4.23.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">PGA5_1</name>
        <name evidence="15" type="ORF">BGZ80_002528</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of proteins with broad specificity similar to that of pepsin A, preferring hydrophobic residues at P1 and P1'. Clots milk and activates trypsinogen. Does not cleave 4-Gln-|-His-5, but does cleave 10-His-|-Leu-11 and 12-Val-|-Glu-13 in B chain of insulin.</text>
            <dbReference type="EC" id="3.4.23.21"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.23.21" evidence="3"/>
    <dbReference type="EMBL" id="JAAAID010001627">
        <property type="protein sequence ID" value="KAG0009302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SX95"/>
    <dbReference type="OrthoDB" id="2747330at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.70.10:FF:000115">
        <property type="entry name" value="Lysosomal aspartic protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF1">
        <property type="entry name" value="ASPARTYL PROTEINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="9 11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 12" id="KW-0645">Protease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040246389" description="rhizopuspepsin" evidence="13">
        <location>
            <begin position="20"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="14">
        <location>
            <begin position="79"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="97"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="281"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="110"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0009302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="394" mass="40913" checksum="25484E2F86A9500C" modified="2023-09-13" version="1">MKIAAFVSLAAAVLAIADASPIHKPNPKGHAVHLTRNPHFKHNVHAQIAKLNKRYPGLQILAGSSGTVPLIDVSPDSEYYGSVSIGTPAQVLKLDFDTGSSDIWFPSSSCTTSACKAHTSFNSAKSSTYQKDGRSWSISYGDGSSASGILGSDIVSVGGIPVRQTIGLATKESSQFASDPVDGMFGLGFDTIESVSGVKTFMDNAIAAGVLAQPVVSVFLPSERVFNGKGGQYLFGAIDNTKYTGSLTYVPVSQEGYWQIAIDDVGYNGQSQGQSSQGIIDTGTTLIIVSDDAASAIHGNIDGSVNDPNNGWLVPCSLSSSTDKISFTMAGTAFNVAVADLAYQDLGDGSGNCVSGVQGGQDLWILGDVFIKNNYCVFSQTSSPSVGIAPLVGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXD7</accession>
    <name>A0A9P6SXD7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Endoplasmic reticulum transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_002334</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Endoplasmic reticulum membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the BCAP29/BCAP31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001570">
        <property type="protein sequence ID" value="KAG0009504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXD7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070973">
        <property type="term" value="P:protein localization to endoplasmic reticulum exit site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008417">
        <property type="entry name" value="BAP29/BAP31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040463">
        <property type="entry name" value="BAP29/BAP31_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12701">
        <property type="entry name" value="BCR-ASSOCIATED PROTEIN, BAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12701:SF20">
        <property type="entry name" value="ENDOPLASMIC RETICULUM TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05529">
        <property type="entry name" value="Bap31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="95"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="BAP29/BAP31 transmembrane" evidence="7">
        <location>
            <begin position="5"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="117"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU367026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0009504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="208" mass="24508" checksum="C04804A4E0788756" modified="2023-09-13" version="1">MSLPYTMMIIFIFLIIPLPFKWRRGLLRFLDESPMMRSAHYVMKIVFIFVFILFIDSLNRVIKVEEIHDSPHHHHGHGSETSVAARRFYAQRNMYLTGFTLFLSLILNRTFFLILDLLKSEEKVEVIKKQAAQQSKEYERVLESETNLKKEIKDLSEVVANNEGAKRDLENLKKQAKQQQQEYLRLADENNAMEMKLRGTKSEAKKDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXL4</accession>
    <name>A0A9P6SXL4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_002486</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001615">
        <property type="protein sequence ID" value="KAG0009344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXL4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0009344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="65" mass="7108" checksum="9937BCC91ED70E76" modified="2023-09-13" version="1" fragment="single">ASLDDEVDGEDESWIYDDNHRPVEDVTLGSSPLGPDADFYTTESSPLGADDPEVEAMWSDSAFEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXM1</accession>
    <name>A0A9P6SXM1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">W2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001658</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001385">
        <property type="protein sequence ID" value="KAG0010228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXM1"/>
    <dbReference type="OrthoDB" id="1727522at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051245">
        <property type="entry name" value="eIF5-mimic_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057397">
        <property type="entry name" value="HEAT_5MP1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003307">
        <property type="entry name" value="W2_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14208">
        <property type="entry name" value="BASIC LEUCINE ZIPPER AND W2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14208:SF2">
        <property type="entry name" value="PROTEIN KRASAVIETZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25504">
        <property type="entry name" value="HEAT_5MP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02020">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00515">
        <property type="entry name" value="eIF5C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51363">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="W2" evidence="1">
        <location>
            <begin position="251"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0010228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="421" mass="47793" checksum="3785C51DB062B1AD" modified="2023-09-13" version="1">MSSASNAKPVLQGVKIRPRKGVQKATAKFEPTVFRDAFIGVISSAAPGNLDDLSTKLDAAGNTLEYRRYAETLFEILIAGRLLAPGGTFLEDGTPASPFSIFQAQDDLASIRKYVEVFHKLMRRYKYLQRGFEDTLSNLLQYVNKFTSEDSNKLAIATGLFCSSGLASLTVLTVLFKEHLVKEGLSLQFVTTVFKTYLIDQTVDQFGLNLHKAGMSDRLLDFFPPNKRDEDSFARHFEAEDMKQLVTFQTKKQLILRKDSIVENVKTHLEEGKLNECLVYLKTQSKESGLTEPELIPLIWTGMMASVDWGTRVDQIDNQILKQVQQYSKLLGAFCTSPKTEIALMQTIQVNFYEDARFIKQYRAVTQLLYKNDVLSESAILYWAEKGSKTQGRTVFMKQMEPFIHWLKNASDEEDSEEDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXP7</accession>
    <name>A0A9P6SXP7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">1-phosphatidylinositol-4-phosphate 5-kinase</fullName>
            <ecNumber evidence="2">2.7.1.68</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">1-phosphatidylinositol 4-phosphate kinase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Diphosphoinositide kinase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">PIP5K</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">MSS4_1</name>
        <name evidence="14" type="ORF">BGZ80_001776</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14425"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58178"/>
            <dbReference type="ChEBI" id="CHEBI:58456"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.68"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.68" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010001411">
        <property type="protein sequence ID" value="KAG0010117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXP7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016308">
        <property type="term" value="F:1-phosphatidylinositol-4-phosphate 5-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd17303">
        <property type="entry name" value="PIPKc_PIP5K_yeast_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.800.10:FF:000009">
        <property type="entry name" value="Phosphatidylinositol 4-phosphate 5-kinase its3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.810.10">
        <property type="entry name" value="2-Layer Sandwich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.800.10">
        <property type="entry name" value="Phosphatidylinositol Phosphate Kinase II Beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027483">
        <property type="entry name" value="PInositol-4-P-4/5-kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002498">
        <property type="entry name" value="PInositol-4-P-4/5-kinase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027484">
        <property type="entry name" value="PInositol-4-P-5-kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023610">
        <property type="entry name" value="PInositol-4/5-P-5/4-kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23086:SF8">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 5-PHOSPHATE 4-KINASE, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23086">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01504">
        <property type="entry name" value="PIP5K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00330">
        <property type="entry name" value="PIPKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56104">
        <property type="entry name" value="SAICAR synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51455">
        <property type="entry name" value="PIPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PIPK" evidence="13">
        <location>
            <begin position="389"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="117"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="164"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="14"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="33"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="117"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="171"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="199"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="219"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="234"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="303"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00078403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00080374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00082306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0010117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="808" mass="90205" checksum="13DBF80C357E75F0" modified="2023-09-13" version="1">MTPPRISSLSPTQPTFPPFHQPHSPPPSPPRVSSPNGYFYDLNQSNPNGVVKTNGYLSHNHHQRSFELEPSPTLSATETFPVSLTATSSSTPASSISTSLSSQQPNHIDLALAALSASPPRASTSTISSNPSTSATRPRPSSYAPTKVTDVSSTLVNLSTLATLPIPPASSVPTSASSSPMVNLTPTFVPNPESKATAQEPPQEQPQSIEPVSKESDPQPLSISSQPPNMSVSPTTPTTTTTTTPTTPTTPTATTTAAGAAGAGGGYNKARLSHPGHFAPPTRASTMDYRSVRSKSALLGESPASSKQQQLDSQAESSGRSKRKQIYRRNTYSADLASNSFHRSDDELEMDELEEARRRMDALKKSSSRRMSKRKKDDDDRVLIGTRIGEDHVNYVLMYNMLTGIRVSVSRCQAKLQRPLVDEDFTSAHKLAFDITGNELTPSSKYDFKFKDYAPWVFRNLREDFHIDASDYLVSLTSKYILSELGSPGKSGSFFYFSQDYRFIIKTIHHTEHKFMRKILKDYFNHVKQNPHTLLCRFFGLHRVKLPHGRKIHFVVMGNVFPPNRDIHETYDLKGSTLGRAISDEELANNPRATQKDLNWANRNRKLELGPEKRHLFVEQLKRDVELLARLNIMDYSLLIGIHDIERGNKDNIRDNTLKVFQPDTKKQLAREPSRRDKRESKVNALRMAVKESDPVAIGPSALPSYSFSERRRCVFYADDGGLLSTNEQNVQGVDLYYLGIIDILTPYNYVKKVEHYWKSMSQDKVGIPLHNYMLFLESCNIGRMIHALRVNNDVLEVLDKKSHPHSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SY63</accession>
    <name>A0A9P6SY63_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">tRNA binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_001671</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001389">
        <property type="protein sequence ID" value="KAG0010205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SY63"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990883">
        <property type="term" value="F:18S rRNA cytidine N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904812">
        <property type="term" value="P:rRNA acetylation involved in maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032672">
        <property type="entry name" value="TmcA/NAT10/Kre33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027992">
        <property type="entry name" value="tRNA_bind_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10925">
        <property type="entry name" value="N-ACETYLTRANSFERASE 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10925:SF5">
        <property type="entry name" value="RNA CYTIDINE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13718">
        <property type="entry name" value="GNAT_acetyltr_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13725">
        <property type="entry name" value="tRNA_bind_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="3"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="Possible tRNA binding" evidence="3">
        <location>
            <begin position="87"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="273"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="386"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="273"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="287"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="386"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0010205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="406" mass="45711" checksum="9FD772F78C2D5462" modified="2023-09-13" version="1">MTDDIKVRDPKKMPPLLLKLSEKKAEKLHWLGVSYGLTAPLHKFWSKAGYVPVYLRQTPNDLTGEHTCVMLRTLESSQTQTQCDPMWLSSFAKDFHHRFQSLLSFQFRSFSATLALSILESARAAKQANADDEASEEDKNSTGVLVKRLREGQVSRELVDALFSAYDLKRLEGYANQVLDYHVILDLVPLVASIWFDGRVDNSEFKLTNIQAALLLAVGLQRKTIDDFEKEIGLSASQLLAFFIKMIRKFSDLFKEQKTLAYTEEINNARATISAQQSNKSTGGNKAKRDVTKEEQWDPNTEDLDDELGKEGRERLRELQKASLGDVEKMYAIAKDDSVDWSMAEAQIDKKGKSTVVSVKNPESTKKRNLVMGGTANDVLAKEAKELVRGKASRRDGGKSAKRRKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZ58</accession>
    <name>A0A9P6SZ58_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_011615</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000956">
        <property type="protein sequence ID" value="KAG0012629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZ58"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0012629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="87" mass="9589" checksum="7BC9567CDE6E3E20" modified="2023-09-13" version="1">MKETLPGFIADHEFHLKANGSNGHYVGDKVVSRAAIMAEFEKSEELMKVRKAVERNPDIAAWRASDECRKLVQGSIIGYGKSTVPGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZ66</accession>
    <name>A0A9P6SZ66_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Spermatogenesis associated protein 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">SPATA5</name>
        <name evidence="6" type="ORF">BGZ80_011394</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000910">
        <property type="protein sequence ID" value="KAG0012958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZ66"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19503">
        <property type="entry name" value="RecA-like_CDC48_NLV2_r1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19511">
        <property type="entry name" value="RecA-like_CDC48_r2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000661">
        <property type="entry name" value="calmodulin-interacting protein 111 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001985">
        <property type="entry name" value="Chromosome 9, whole genome shotgun sequence"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000069">
        <property type="entry name" value="spermatogenesis-associated protein 5 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050168">
        <property type="entry name" value="AAA_ATPase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077">
        <property type="entry name" value="AAA-FAMILY ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077:SF27">
        <property type="entry name" value="ATPASE FAMILY GENE 2 PROTEIN HOMOLOG A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00830">
        <property type="entry name" value="ENDOLAPTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="5">
        <location>
            <begin position="217"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="5">
        <location>
            <begin position="545"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="319"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="322"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0012958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="781" mass="85718" checksum="9C88B8F7B6969334" modified="2023-09-13" version="1">MKLLAQQSPSARSVRAVRKAFLNGSVAIAWPSFTVSENHIQLSSVSRLNANVAVGDPVEITRIESPIHEASQISLTALHSIPFVSNILFTLFTKEIMTEIRFVIKDNYVEFPYNGRPQRFKVTGILLDLKEQRHGSVFAVGQETVVKVVPFTPSQSALHKEILEEAGAINGDSDKERQQSRPYDQIGGLGAQIKTVREMVEIPLHNPEVFTQFGLRPPKGVLLYGPPGTGKTLIARTVAAATGAYLTVINGPEIISKFYGETEAKLRAIFELSAENSPSIIFIDEIDALCPKRDEAASEMEKRVVATLLTLMDGVSEKKIPSTAKSTTSDSKTTSETSTPRIVVMGATNRPNALDEALRRPGRFDREVEIGIPNANARAEILTALLRKIPNTVTTTQIEHLASISHGYVGADLAAVCREAGLKTINRVTEKHRRVLEMDIDTFQGSQTSSDLQLRFEALTVSGSSGNDQSICQQEQDDELKVSAEDLRAAMTDVKPSAMREIMIEVPKVLWSDIGGQAEIKQKLKESVEWPLQHPDAFIRMGIRPPKGILLYGPPGCSKTLMAKALATQAGLNFIAVKGPELFSKWVGESEKAVREVFRKARAASPSIVFFDEIDALTVKRGSGDDGGSSVADRVLSQLLNELDGIEPLVNVTVVAATNRPDIMDPALMRPGRIDRILYVSPPDLPSRREILRLHIHSKKMACDADVDIEQLAEQTEGCSGAEVVALCQEAAMKAMEESLEIACVSKRHFEQALAGMTRRITKEMIQFYDDFRMRSGLKSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZF8</accession>
    <name>A0A9P6SZF8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_011022</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000836">
        <property type="protein sequence ID" value="KAG0013512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZF8"/>
    <dbReference type="OrthoDB" id="2441498at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="65"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0013512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="154" mass="16143" checksum="061EA0E412306E10" modified="2023-09-13" version="1" fragment="single">MSNPSTHFESNSSLMASQNSAPGPYGGGGYGSLYGTMSHSMNLGHPNSYTVPGPGTPPVLPPLQPNNNNNGGANPYGSHGNHSGFQFSYQSDAGSMTPSPALATPTGIHALNPMDGQLDPSRRSVDDLDTRKQTQPPHSQQIIDGFQKGQQQLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZM0</accession>
    <name>A0A9P6SZM0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_010985</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000828">
        <property type="protein sequence ID" value="KAG0013575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZM0"/>
    <dbReference type="OrthoDB" id="2595509at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="241"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0013575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="300" mass="33117" checksum="8FD98B721FF8FFE1" modified="2023-09-13" version="1">MTSTRPREGRGVRHTAGGEHDRLKRAVLQPVQCWDKKWTDSKNGKQLQVFKWVKSDRQVDFDDDDDDEEIEQAPVPHQAEEIEEVGTPAPALPTLQDADDTTASTPMQTGEEDDEDDGDGPPKTGSHPLSQSYSEADRRPSSSGRLEIMSQKSGRHDKKIIQEDRDGDDEDDTDSSRPLVFTPSLETPIETQANTPQDFESMSPAPVEIDELKREAQVEMVVKGLDEGQAEMEEEMEEVVVKEKEHAHPAGDGIDEAQSVAVDSRRAVSEAIESDSLLSSSDVNTRDNNMDVDPSLGPAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZT9</accession>
    <name>A0A9P6SZT9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">5-formyltetrahydrofolate cyclo-ligase</fullName>
            <ecNumber evidence="5">6.3.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_010715</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(6S)-5-formyl-5,6,7,8-tetrahydrofolate + ATP = (6R)-5,10-methenyltetrahydrofolate + ADP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10488"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57455"/>
            <dbReference type="ChEBI" id="CHEBI:57457"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.3.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.3.2" evidence="5"/>
    <dbReference type="EMBL" id="JAAAID010000778">
        <property type="protein sequence ID" value="KAG0013999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZT9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030272">
        <property type="term" value="F:5-formyltetrahydrofolate cyclo-ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009396">
        <property type="term" value="P:folic acid-containing compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10420">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002698">
        <property type="entry name" value="FTHF_cligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024185">
        <property type="entry name" value="FTHF_cligase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23407:SF1">
        <property type="entry name" value="5-FORMYLTETRAHYDROFOLATE CYCLO-LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23407">
        <property type="entry name" value="ATPASE INHIBITOR/5-FORMYLTETRAHYDROFOLATE CYCLO-LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01812">
        <property type="entry name" value="5-FTHF_cyc-lig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00036539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0013999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="73" mass="8504" checksum="9DFC7FDCE1BE40C3" modified="2023-09-13" version="1" fragment="single">MNPALRTLKNTIRKEMRQKLAALSTEEITRQTAIVTEKLIEMPEFKESQNVSVYISMHGEICTRDIIRELLNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZV7</accession>
    <name>A0A9P6SZV7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_011081</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000847">
        <property type="protein sequence ID" value="KAG0013431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZV7"/>
    <dbReference type="OrthoDB" id="439808at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236:SF95">
        <property type="entry name" value="NUCLEOLAR PROTEIN 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="197"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="302"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="386"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="52"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="91"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="113"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="137"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="155"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="184"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="424"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0013431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="486" mass="53523" checksum="9D2E35F708B94052" modified="2023-09-13" version="1">MDVADEPYDFLTWHSNAPVVKDEKKEKKRLKKLEKETKEKAEKSAKKDSSKSKSKKDTKKKRKSAQSDDESGSDSDADEDEDEDDEENKTPVKKSKEVRKKKQVKESEESGSESESSASDSSSSEESDDPDTQPPPKSKRKKNKKKNKKKAGGGDDGDEAEAPENEESDEGEGGGGKKKSKKGNKSEKAGPGRKGEFGIWIGNLSFLTTEKALRHFFRNVGADITRVNMPSGSGYNKKGNKGFAYVDFASAEAQINAIKLSESELDGRKVLIKSSKSFEGRPALSKGAVQEKATKQKHAVSPTLFVGNLSFQTTRESLQRLFEDCGEIRKVRLATFEDSGKCKGFGYIDYMSPESATAALTNPQKYFLDGRKLNIEYASAEATLKGNPREYRKHKRDEEEAAAVARGEIPASHKEGASAEDADAAAKAEEERRKFNAEQKAKRQRRQPGEAPAKKLQGHQRPGLALANAQRAPQGIVEFKGSKVTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZW8</accession>
    <name>A0A9P6SZW8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 13">Nucleoside diphosphate kinase</fullName>
            <ecNumber evidence="13">2.7.4.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">NME6</name>
        <name evidence="15" type="ORF">BGZ80_011028</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a 2'-deoxyribonucleoside 5'-diphosphate + ATP = a 2'-deoxyribonucleoside 5'-triphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:44640"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:73316"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.6"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 11 12">Belongs to the NDK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.6" evidence="13"/>
    <dbReference type="EMBL" id="JAAAID010000837">
        <property type="protein sequence ID" value="KAG0013508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZW8"/>
    <dbReference type="OrthoDB" id="2162449at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004550">
        <property type="term" value="F:nucleoside diphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006241">
        <property type="term" value="P:CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006183">
        <property type="term" value="P:GTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006228">
        <property type="term" value="P:UTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.141">
        <property type="entry name" value="Nucleoside diphosphate kinase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034907">
        <property type="entry name" value="NDK-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036850">
        <property type="entry name" value="NDK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001564">
        <property type="entry name" value="Nucleoside_diP_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023005">
        <property type="entry name" value="Nucleoside_diP_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46161">
        <property type="entry name" value="NUCLEOSIDE DIPHOSPHATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46161:SF3">
        <property type="entry name" value="NUCLEOSIDE DIPHOSPHATE KINASE DDB_G0292928-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00334">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01243">
        <property type="entry name" value="NUCDPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00562">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54919">
        <property type="entry name" value="Nucleoside diphosphate kinase, NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00469">
        <property type="entry name" value="NDPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51374">
        <property type="entry name" value="NDPK_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 13 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="6 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Nucleoside diphosphate kinase-like" evidence="14">
        <location>
            <begin position="7"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="active site" description="Pros-phosphohistidine intermediate" evidence="11">
        <location>
            <position position="125"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0013508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="166" mass="19141" checksum="DD874C93F6F0793F" modified="2023-09-13" version="1">MPPRPLTQLTLALLKPDLAANSVKVNKVFAHIQQNDFQILKHKQLLWSKSDAEAFYGEHRGKFFFERLCGYMTSGHFHALILEKPNAITDWRALIGPTHPPRARINAPGTLRSLYGMTDTRNSFHGSDAVETARNEIKFFFPEFDIEKWEQDQAKNSQHDHRSIKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T088</accession>
    <name>A0A9P6T088_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_010123</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000671">
        <property type="protein sequence ID" value="KAG0014989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T088"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019034">
        <property type="entry name" value="UPF0390"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09495">
        <property type="entry name" value="DUF2462"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="66"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0014989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="90" mass="9355" checksum="84C06EBF6CDE1C2F" modified="2023-09-13" version="1" fragment="single">RSYAPKSNVLIKQKSTQKKLSAQINKNIETVMATRAGATGKLTIMKGLADAGLAAERKAGGKKKAGGMPKVSTGKTIKAMPTKAKTAAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0H6</accession>
    <name>A0A9P6T0H6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transcriptional activator HAP2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">HAP2_3</name>
        <name evidence="9" type="ORF">BGZ80_010240</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Heterotrimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the NFYA/HAP2 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000693">
        <property type="protein sequence ID" value="KAG0014766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0H6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016602">
        <property type="term" value="C:CCAAT-binding factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018362">
        <property type="entry name" value="CCAAT-binding_factor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001289">
        <property type="entry name" value="NFYA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12632">
        <property type="entry name" value="TRANSCRIPTION FACTOR NF-Y ALPHA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02045">
        <property type="entry name" value="CBFB_NFYA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00616">
        <property type="entry name" value="CCAATSUBUNTB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00521">
        <property type="entry name" value="CBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00686">
        <property type="entry name" value="NFYA_HAP2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51152">
        <property type="entry name" value="NFYA_HAP2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0010">Activator</keyword>
    <keyword evidence="3 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 7" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="78"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="131"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="219"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="11"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="142"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="219"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="234"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="254"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="272"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="355"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0014766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="368" mass="40001" checksum="D0A651E9417789CB" modified="2023-09-13" version="1">MMGPQSPTDSDQDHHHQQQYHDHHEQIPATAPPHALPPSHNAGAEEEPLYVNAKQYHRILKRRAARAKLEEMNRMAKIRKPYLHESRHKHAMRRPRGPGGRFLTSHEIANLDRLQASFEALGGVGPVGGDMHLASSNYTPEQQQQILQQQVQIQRQQQLQNQPGQQPFMPQQQPQQGQQGPQSRQEQQSQQQQMLQQQQQIPLPLQNQIQGGQQQQDLFTTGTFNNQPFGQDGSSSSSSHSLPSMMNGPPGSENGVGGSGGNSNTGPLNVRNLLQGNYHNNNGHPLTPSTSNANTPSAGGVGPDLSSLVHNHHHNGGGVVGEDDQGEGSGTTGQLVNIPESQGGFGEQQDEPQDDNGSSSLLTPTGDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0J9</accession>
    <name>A0A9P6T0J9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Ribosomal L1 domain-containing protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BGZ80_009709</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Regulates cellular senescence through inhibition of PTEN translation. Acts as a pro-apoptotic regulator in response to DNA damage.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the universal ribosomal protein uL1 family. Highly divergent.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000605">
        <property type="protein sequence ID" value="KAG0015689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0J9"/>
    <dbReference type="OrthoDB" id="10251727at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00403">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.790:FF:000004">
        <property type="entry name" value="Ribosomal L1 domain-containing 1-like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050257">
        <property type="entry name" value="eL8/uL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023674">
        <property type="entry name" value="Ribosomal_uL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028364">
        <property type="entry name" value="Ribosomal_uL1/biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016095">
        <property type="entry name" value="Ribosomal_uL1_3-a/b-sand"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23105">
        <property type="entry name" value="RIBOSOMAL PROTEIN L7AE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00687">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56808">
        <property type="entry name" value="Ribosomal protein L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0007">Acetylation</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0832">Ubl conjugation</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="241"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="241"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="252"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00054167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00061550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00070787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0015689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="271" mass="30342" checksum="3A5B5A1CC78700B9" modified="2023-09-13" version="1">MLDIKQADRAVKALLGHISKRGESKDQLIDDDQAVWLIIATKKFSDESKAKPHRIPLKHSITAPDAEVCLFVKDPQKDYKRLLEEKNVKAVSKVIGVSKLRAKYKPYEAKRQLCASYGMFLSDARVVTMLPKMLGKTFFLKKKQPIPVDMTKKDLKKEIARAIGSTYMHQTSGTCTAIKIGLTSQTSAQITANIETAIPHIIAKIPRQWKNIQAINLKTNDSIALPIFNSLPNEGITRITVSGRSSKTSSMEVDEEDGEDEDEDEDEEDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0Z2</accession>
    <name>A0A9P6T0Z2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008560</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000468">
        <property type="protein sequence ID" value="KAG0017160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0Z2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="671"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="745"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="685"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="704"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="759"/>
            <end position="786"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0017160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="885" mass="98438" checksum="3B7FF4FB618280A7" modified="2023-09-13" version="1">MSTQRPPLPHLKDIKAPLFGSWEFWMIDIETELVATLNQLVATKTTAKSFAVPPHTIESLIKISLIAPYQVVAKVVGNAMINRGQSTILLEVLVNLGQLSWLRSDPTEKILLVAVIHDIMLSEHKSEETLSDQKNQHRNFVEFILKAFVKRSPVNQVALDATDFLKECVEPLIDTIVEGTETSFFSPVVAILMKLYQPEFGASVIDEEWLSQDTHLKILLQLLLLRTVKSSWTASQMCGHAKPRTTIRQLPRDKQEDVVGDSLEDISKLSELLVSRLSAHVGSMALRDDNSYEGIDNFLQAIGEQDGSIDLESRLIAAPFIITCQQHLHKNVQLPVLPKEIWPLCRNYLKLFSLCQPTSQHVQGVDLLQALLIVLDVGRMCDDIILDITQAIGQVKDLSLVDQGHLMQALIPLLYRVLSISSRSEGHRLLARGIPAMMKYWGELPDLAFYWDVADEKPRKRLGSYWDAFSLCKFYTAEREESQQGQESWDGFSSEEVVVAVLMTSEMLLRFALEPLTPKSPSMVLQVYRMFVGYDVMVDHMASLVLSSIKFVKVDWSTAPLDFVLFCFMIICRLSNIVSNEHMNKPLKNRFGHTSLDPTLLAATEFGDWTSAYSNFMSQQCDKVEQQELVARSKARDELVLAAMNLSEEIVRRQDNYYKPEDESMDGILESSVGADKNGSATQSKGKKRGNKGNKRGRGGKTKCSLESRDPYRDDDSASLNIVTASNVMDEGTRAWFNSIMSTSNGSAMQGNPKPDTGATLNATPSDSQQHQNQCPQPPISSTAPSTPEPALPDHDVDPSIPIVVSTEAAVPIDSIDLENNENSITLSSASETVKPMLSSDQIDCLTLALDYLPTQERLAVGSRLSRLLEAADENNLPESGSSIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1D5</accession>
    <name>A0A9P6T1D5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">LYR motif-containing protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">LYRM2</name>
        <name evidence="5" type="ORF">BGZ80_007818</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000408">
        <property type="protein sequence ID" value="KAG0017872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1D5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd20262">
        <property type="entry name" value="Complex1_LYR_LYRM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050863">
        <property type="entry name" value="CenT-Element_Derived"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008011">
        <property type="entry name" value="Complex1_LYR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045293">
        <property type="entry name" value="Complex1_LYR_LYRM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006600">
        <property type="entry name" value="HTH_CenpB_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007889">
        <property type="entry name" value="HTH_Psq"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19303:SF73">
        <property type="entry name" value="PROTEIN PDC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19303">
        <property type="entry name" value="TRANSPOSON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04218">
        <property type="entry name" value="CENP-B_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05347">
        <property type="entry name" value="Complex1_LYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03221">
        <property type="entry name" value="HTH_Tnp_Tc5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51253">
        <property type="entry name" value="HTH_CENPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH CENPB-type" evidence="4">
        <location>
            <begin position="242"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="41"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="59"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0017872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="709" mass="81252" checksum="D8A02DEF801F1761" modified="2023-09-13" version="1">MLDHSDHFTYTGHDSNGFNQEGMMPECYDWPLPQSCKYQVQAQPPMNPSPQAEDAASSIFPNPTGQPQTPTYQELTQQCIPPVSLQSHCHESMLFMAQQAEMQFMGNMQILDSNIQIEKPYLQIVQIPSQQQMHEMQKKLPYSHQGVESSGSLQIYCDAKRSSESADSVSVASKRKRTAISLQDKGKVLNYVDQNPDATIIEIADRFQMCRTTIYGIMNSRSRILERLNGVTNLPQASLVHDSYRVSESRFLILEELLAIWLKDLKQQWIQVSDNKIMTQARELYRMLSDRPQVPMDPCRFTSGWLKGFQKRKNINPRGTRKKIGSESLSVEGENHFASLRVRRYKKCDIYSCETTSMHLNFVAPNFLQEKSQDKATVRQGEPLALKAIGYHEMVDDAEAEDLKKGTLIRWLMEFDRTLVHPILLFVDEAIWRLLSFDGEDSGSYLRLIDVIKVPGRHAGSSPMGAGIAKEFKSSYYWHLISALNHRAESLGGVENNSKKLDTLEEHLGLILTAWDKIHSRDIKRLFQKFLEPIGPAADDIASRSQSIQSFYYSTMLPGHIKDSFPEMSNAVIQYFANLDKDTGPSSFMRSKIQQISRHPDFFRYFKHGGVDIVRVAKLYPESRFDLDFLTRARVLSLYRDIQRAIRSVKDPKDRQDLQTWARSDFERYRHETNPDKIKSLISQGKHQFHALQTNLSLSSGQDSKSGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1T4</accession>
    <name>A0A9P6T1T4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_007221</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000366">
        <property type="protein sequence ID" value="KAG0018393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1T4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040403047" evidence="2">
        <location>
            <begin position="26"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0018393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="192" mass="21869" checksum="431F3A2238FAB1A6" modified="2023-09-13" version="1">MRLAKGHLKYFLYLVVQLVILVKHSITPYHGQGLVVAQKKLGFFKQAPLNLENIASETLEEQQRQEKTLGVYWKLWRQSLLKATEAESLSDSSGTDKNVAGIKESKKPTGHDDDIVHNFGHTDNEAYGGIVWYDRLHREDEEEHEEQDDHHHDHDDEAVENDIITVTTTTTTTMRCSSGAHFAHRVLSTPQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T212</accession>
    <name>A0A9P6T212_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Mitochondrial import inner membrane translocase subunit TIM14</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Presequence translocated-associated motor subunit PAM18</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">DNAJC15</name>
        <name evidence="11" type="ORF">BGZ80_005738</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the TIM14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000282">
        <property type="protein sequence ID" value="KAG0019497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T212"/>
    <dbReference type="OrthoDB" id="240298at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001405">
        <property type="term" value="C:PAM complex, Tim23 associated import motor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001671">
        <property type="term" value="F:ATPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.110:FF:000001">
        <property type="entry name" value="Import inner membrane translocase subunit tim14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12763">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12763:SF28">
        <property type="entry name" value="GEO10507P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="J" evidence="10">
        <location>
            <begin position="60"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00040828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00041716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0019497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="112" mass="12027" checksum="8640E75D75840374" modified="2023-09-13" version="1">MSTPLLIGVGIAGAAYGTKIALRTWELHGAKIMAAIPRPGTIGAGKYYKGGFETKMDKREAALILGLKESGLNSAKLKEAHRRIMLLNHPDRGGSPFLASKINEAKDLLDKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2A5</accession>
    <name>A0A9P6T2A5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ima1 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_005305</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000262">
        <property type="protein sequence ID" value="KAG0019764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2A5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034506">
        <property type="term" value="C:chromosome, centromeric core domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034992">
        <property type="term" value="C:microtubule organizing center attachment site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044732">
        <property type="term" value="C:mitotic spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005637">
        <property type="term" value="C:nuclear inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071765">
        <property type="term" value="P:nuclear inner membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042321">
        <property type="entry name" value="Ima1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018617">
        <property type="entry name" value="Ima1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28538">
        <property type="entry name" value="INTEGRAL INNER NUCLEAR MEMBRANE PROTEIN IMA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28538:SF1">
        <property type="entry name" value="INTEGRAL INNER NUCLEAR MEMBRANE PROTEIN IMA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09779">
        <property type="entry name" value="Ima1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="247"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="286"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="316"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="680"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="704"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="763"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="841"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="domain" description="Ima1 N-terminal" evidence="8">
        <location>
            <begin position="43"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="352"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="402"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="566"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="371"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="569"/>
            <end position="578"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF09779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0019764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="888" mass="99694" checksum="71AAFAACD96ECDED" modified="2023-09-13" version="1">MGATHLDWSDQQQGLYSTISLQKRINKNYCSGDQILAKLATANTRSLKNRKRPSSGVSNKPVENDFFCEICNGHQRVVYQLLSNYIPDEEDENYDAYYENADTYKRQLEERYPMACAKCMEKVQKELAQQNYRIKSSLLNATLNKSRGDKIRPTRKYPSVGWLFTGSSWLCAHGALLSVETINFFGPDVLPSSRIFTLPKRLAQSAGSLTLHNLTGALSKLNPPTQLLWSQSSGNPLLRLTEAEQSSVFAITLICLSIWGLYWDPLDFVMQRAPRIKIRARQYYKWVRASTIPLLIIQYYSLFFGRWQLDLNWSRGIPLLLHALYIAAFFNGRYIQEPNEVKFDSLTSYPSTSKTSAHGNVSGDDKRKATAKTSNSHATPSRSPAHSSESYFTSASRSFEDISRSQTSSPEINEINWSPKKSAPLASNRLSAAFGMYRDSNQSTRQDDTMMNTLPKLGHTGSLQEQQSRGFDYKPDNKFRSRAYEPSPLANPSLVTNMGLSNMSLGEMFGFPSAKFQPPENHFAHRSASQQGAGVSDAWSYRRTTEAGSANGHASNHRTRNRFSQSADFDMDEDDEDSQNLTSLSRRSAGPISMDTDHTNDIFSSFGFGSTTAHSTGNSYSKGSGSFAPQRYFPPEPETGLEDNFLGIVKIVDDYLPPQQGPRSIAGRNLMLKKRMARRWLSLLLFCRCIVLWRALSGGWKLDWVTQVIFAGAILHAAAFWFLDEYRLLKRYLDKESSSLETKKTSNDIDPFEPTVIDRVCSYLLLLLLAARILNMISWILVDKVSLGNLSATEDTCLLQDEIPGERCHEPTVGHPSLMDWSPGAIRLVYPGVGREEAAMAVAYFAGWMHDIAMIALFVVLVAFGAGSHTIKTNQSPAQEHKVRRRGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3I3</accession>
    <name>A0A9P6T3I3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Inhibitor I9 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_000083</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protease inhibitor I9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000101">
        <property type="protein sequence ID" value="KAG0022512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3I3"/>
    <dbReference type="OrthoDB" id="5518345at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004866">
        <property type="term" value="F:endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042144">
        <property type="term" value="P:vacuole fusion, non-autophagic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.80">
        <property type="entry name" value="Peptidase S8 propeptide/proteinase inhibitor I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052471">
        <property type="entry name" value="PBI_I9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010259">
        <property type="entry name" value="S8pro/Inhibitor_I9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037045">
        <property type="entry name" value="S8pro/Inhibitor_I9_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28288">
        <property type="entry name" value="PROTEASE B INHIBITOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28288:SF2">
        <property type="entry name" value="PROTEASE B INHIBITOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05922">
        <property type="entry name" value="Inhibitor_I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54897">
        <property type="entry name" value="Protease propeptides/inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Inhibitor I9" evidence="2">
        <location>
            <begin position="19"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0022512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="80" mass="8574" checksum="69FEF08AAEA34582" modified="2023-09-13" version="1">MTNKVIVIFKKGTEPSVIEAAAKDIESQGGKIGHRYNSALLGFSAEVPDVGINALITHANVDYVEPDGEVSAYTKDLLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3T9</accession>
    <name>A0A9P6T3T9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mid2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_010296</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000070">
        <property type="protein sequence ID" value="KAG0023139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3T9"/>
    <dbReference type="OrthoDB" id="2443093at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040372236" description="Mid2 domain-containing protein" evidence="3">
        <location>
            <begin position="26"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="291"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="146"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="185"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0023139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="498" mass="52771" checksum="085535502FDF4DD6" modified="2023-09-13" version="1">MRFTTLSLVLAVSAILSSLPTACNAQEANSASPVGTEGQPRVAFNRQSKVPYIPNSGVEHTQFTPVDYSQAGNVVRRSTTLPEYSGISRSHGTGRTSPSLQSQMEQKRPKRLIKRIGPRRLAGERRDSLLDSLVNEDPPLADDEPVPSSSSSPDPSTTSENSAPSSTDNEDGEPASASAQEQEPTTTTTTTTTTTTTTTTTTTTAAVATATTTDTTTATESPEPTPDASSPSDTSEIVDTTNGNDEDTTTSSKAKDSNSGPTTTDDGQDDVQRPDDNDDNSTVETSNDNKGVTIGILVAAVIVACVIGVWIVRKWKLSPSRHFKSKIAGGAGGAGCAAAGGYHQHDNASDYNSYDNILRHDSATSISIPPQPPMESVATNPAIAAAAMVTPTTAYQPHAHGYNQEYQNQDYAYSHQEHYEECQGYSGYQEYPHHMNAADSTGDYGNYRHSAGSTSLGASSAAAMLPSTGRAPNTGHNINGHMSEDYSQNDHFLRELRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T435</accession>
    <name>A0A9P6T435_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Sorting nexin/Vps5-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_008467</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000046">
        <property type="protein sequence ID" value="KAG0023696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T435"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015404">
        <property type="entry name" value="Vps5_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10555:SF170">
        <property type="entry name" value="FI18122P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10555">
        <property type="entry name" value="SORTING NEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09325">
        <property type="entry name" value="Vps5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sorting nexin/Vps5-like C-terminal" evidence="3">
        <location>
            <begin position="106"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="349"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="446"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="548"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="271"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="353"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="470"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="500"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0023696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="567" mass="62915" checksum="7AE7217CAA0C700C" modified="2023-09-13" version="1">MRSLKVSVPEAASSGGTITFKILVNTANSDMSAFVDYVIPPLPESLSEKQYEDVDQVEQKRVQIERFLQRTHLDSIDSKRATLGFLRFDNIIKPSYDRGMRMYRPSENVEENDQGEFQRRQTYILAMEQAFTGILDTGLRLTKEREKLGDMYSQLGDSTMEVLSSKYRLGDGQRIDNRERHQALDEEMQIFGVLSDDLRLSIRRQAKSETFYFTDLVHEYRGMLHGLKDVMNSRTDRLSEYVSASKSVTKRQARLEQAVQKSETSPAADLVDKAQLSLEGANAKLDEAREEFKKSQEIVTRELLRYEKDRAKEWQASVKDYAEKQVFYEKEKLLALEKAWASIQDLRTNAGGELSGGNSGVRGRGPEPSGRSRSYWPSGLGSPFAPDLTREGLTDSLQSGVASNLTPLVTESATQGRLPQNAGPGSANVSNYNNSGYSSGYNSGYNSGYTSGEQDEGARSEPGYFPATKLSRSGSGPRSSKATQSESTGKSGPRKGSLPEMTSSSNIPILTAAVSSGTRDEGSFVPNYSTSPLHLETHSKLDILSAEREDKNKDGYDPLMVRPGFTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T441</accession>
    <name>A0A9P6T441_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">hydroxymethylglutaryl-CoA reductase (NADPH)</fullName>
            <ecNumber evidence="2">1.1.1.34</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_010053</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HMG-CoA reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.34" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010000066">
        <property type="protein sequence ID" value="KAG0023231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T441"/>
    <dbReference type="OrthoDB" id="310654at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004420">
        <property type="term" value="F:hydroxymethylglutaryl-CoA reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015936">
        <property type="term" value="P:coenzyme A metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.660">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.770.10">
        <property type="entry name" value="3-hydroxy-3-methylglutaryl-coenzyme A Reductase, Chain A, domain 2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002202">
        <property type="entry name" value="HMG_CoA_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023074">
        <property type="entry name" value="HMG_CoA_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023076">
        <property type="entry name" value="HMG_CoA_Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009023">
        <property type="entry name" value="HMG_CoA_Rdtase_NAD(P)-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009029">
        <property type="entry name" value="HMG_CoA_Rdtase_sub-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10572">
        <property type="entry name" value="3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10572:SF24">
        <property type="entry name" value="3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00368">
        <property type="entry name" value="HMG-CoA_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55035">
        <property type="entry name" value="NAD-binding domain of HMG-CoA reductase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56542">
        <property type="entry name" value="Substrate-binding domain of HMG-CoA reductase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01192">
        <property type="entry name" value="HMG_COA_REDUCTASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50065">
        <property type="entry name" value="HMG_COA_REDUCTASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="78"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="589"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="591"/>
            <end position="610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0023231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="797" mass="86554" checksum="CC79F6063DF32A0B" modified="2023-09-13" version="1">MTPPPAVTEGGSSAHHPSLFINTSASFTSEVTGASDAHSRWSGFYKKTIKERRTQLRLAYPHLARPSSLDAFASTQTSAMTSGRSTPNLGRSTPNLGPNMRSLTMTNIARPTSTSQTTTSIAMPRPVPLHVATSEKSSILKNPDNLATLQESNLTDNNRDTINRNQEKLASEEIIITDEIVVRPKESSLSEEEFRDQLRLQFQKAEKERQALVLELGQGQEDVAMTEEEQRDQFEKERRANGISDLEEQRKMIGSSNGHLLEGDLSLNARLDALIAAEQEGTPFPVHGLDEQIANNMIENCIGTLGLPLGLAFNFTINGSPLTIPMSIEEPSVVAAVSSAAKTIATYHGFQAWAPERNMIVAQVQLVDIPDSKMDHVMTKMQENEKSIQEEANEYCVNMVKRGGGVQRITFHRIRRHVNREGFKGQDLLVKYGVIPAESLPARGSSNPSQGRCSEWLLVHLHIDVGDAMGANCANTVAEGIAPFLAKLSGGRVGVRILSNLNVDRIAKSTFRLPFSHMGYKSLSGKDVAVRILEAYEWADLDPYRAATHNKGIMNGIDAVALATGQDWRAVEAGAHAWASGAGTYSERSTDAISTRGSSPSDPVSTHINGNGNGNKRKFEAHSEEAKVYRGDAYKPLTRYWIEEDEDRLQQGFTGQDALVFCGELEMPIMVGTKGGVLSTNPVHAFTLGVMRYPDSKQLAMAMVTVGLAQNFAALRALATEGIQRGHMALHARNIAISAGTPPASVDEVTAYMIDTGKIRLGAAKSYIEKRGLLLYSSGLSSNSSSTSLLGNGANVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MC60</accession>
    <name>A0A9P6MC60_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">WD40 repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_008886</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004993">
        <property type="protein sequence ID" value="KAF9991776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MC60"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879:SF9">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="41"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="83"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="125"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9991776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="188" mass="20269" checksum="CA0472B83A9BE0EE" modified="2023-09-13" version="1" fragment="single">GRSGDANDIAYSPNGDQIASVGEDKTVRLWNVETGGVIYILEGHTDEVYSVSYSPKGDQIASGSRDHSIRLWDVETGDLIRVLQGHDGAIFSIAYSPNGGQIASGSGDETVRLWDTETNKCIHTLQGHLDCVSSVAYSPSGGQIASGSWDKTVRLWDIETEQCLAIISGFNGYVNGVAWRNTLNGQYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MC96</accession>
    <name>A0A9P6MC96_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Condensin complex subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">YCS4_4</name>
        <name evidence="1" type="ORF">BGZ80_009212</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010005301">
        <property type="protein sequence ID" value="KAF9991350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MC96"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9991350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="80" mass="9052" checksum="FDE89D9C93A680CD" modified="2023-09-13" version="1" fragment="single">MEVIDEEFKRRKVATGNEKKKGKKNTVHDELDQVVGTTEDEFGDGMAHIRERELLFGEGSLLQVFGPLIVTICGNNTLYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MCX6</accession>
    <name>A0A9P6MCX6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_008568</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004685">
        <property type="protein sequence ID" value="KAF9992396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MCX6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052945">
        <property type="entry name" value="Mitotic_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43628">
        <property type="entry name" value="ACTIVATOR OF C KINASE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43628:SF1">
        <property type="entry name" value="CHITIN SYNTHASE REGULATORY FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9992396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="259" mass="29034" checksum="76ED2E719D5CA49D" modified="2023-09-13" version="1" fragment="single">NIIESRKVVEHDYSKAYERYLEAANQGCADAQSNLGFLYQVGYGVTKDEAKAVEWYQKATEQGHTYAHCNLGFMYDRGFGIDQDYVKAVELYRVSADAGCARAQTNLGYLYGDGSGITQDHSKALEMYQKAADQGYPKGQYNLGVMYEVGNGVTQDYPKAVEWYQKAANQGDAEAQCNLGVMYINGRGVVQDFSKALEWFHKAADRGNEVALFNLGMVYEHDNGIQDYSKALEWYRKSANKGHIDAQFNAAIMYRDGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MDF1</accession>
    <name>A0A9P6MDF1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008212</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004390">
        <property type="protein sequence ID" value="KAF9993253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MDF1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9993253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="96" mass="10923" checksum="7D865976BFFF01AE" modified="2023-09-13" version="1" fragment="single">SAFEEYYNERFPQAKADLESSRKVAGLVSGQTWKDDIMRKIVLNLMPSSLTKMAVVRTLAYRPQASFLPKVEYHGSGRVDPQKESKRYLQEKAAAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MDS0</accession>
    <name>A0A9P6MDS0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007998</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004205">
        <property type="protein sequence ID" value="KAF9993897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MDS0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="24"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="59"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="80"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9993897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="153" mass="16034" checksum="4D92757668A14FEC" modified="2023-09-13" version="1" fragment="single">SSDLLANDDGQDEQQNSADAFQDPLSSSSSSSPLPVASFSRRAATVSAGSSPMPGLPGRRTSSSTSSTRSSILSKDSIFSAPTSTRRGSSTSESAAGPGRERSASNASKETEEPTPKDVTLMAQGTQAYSLLKRIQEHPIELADIIRMLVTKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MEI9</accession>
    <name>A0A9P6MEI9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007629</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003940">
        <property type="protein sequence ID" value="KAF9995019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MEI9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9995019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="57" mass="6524" checksum="42706EEB4AFD4486" modified="2023-09-13" version="1" fragment="single">MCSWFNPKTTRTEVLPQSDDPKLSSVDSFAYQVNIIITDPLQEGRRRDSIQRNSPGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MGI9</accession>
    <name>A0A9P6MGI9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_006639</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003288">
        <property type="protein sequence ID" value="KAF9999090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MGI9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043066">
        <property type="term" value="P:negative regulation of apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045719">
        <property type="term" value="P:negative regulation of glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000314">
        <property type="entry name" value="Serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017348">
        <property type="entry name" value="PIM1/2/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF72">
        <property type="entry name" value="CAMK PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037993">
        <property type="entry name" value="STPK_Pim-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="53"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="163"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="169"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="255"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="216"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR037993-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR037993-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9999090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="393" mass="43240" checksum="BE5566DAF2F5876A" modified="2023-09-13" version="1">MAAIIDATFDPTTQGPLTPPPAPMDSHADDSKLTVSARHLQHHALVPEFVSEYTLGDELGSGGFGFVVSATRNSDHKEVAVKFIFREKVPVHGWAKDPELGVIPMEIYALRNVSHPNIIGFLGSYQDSRFFYLVMELHGTPWSASNPLLSSKNGMMDAITNATLSQKRSGSGSASTTSSGSTSYSTSTSSSSSSLSHLADDDVPKPALLVRRTSCDLFECIEHHSKFSESQAHMIFRQIVDCVHYLNSRGICHRDIKDENIVIDNDFCVKLIDFGSAVIIPPQGKVFDRFYGTINYASPEILKGEKYRAESAEIWSLGILLYTILYGEVPFNDPVQAISGPYITPRVQSSKECLHLLNWMLAKAPEARATIADVANHPWVLGIRDRFMPLPPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MH43</accession>
    <name>A0A9P6MH43_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_006377</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003146">
        <property type="protein sequence ID" value="KAG0000367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MH43"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="250"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="323"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="361"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="330"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="365"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0000367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="414" mass="46266" checksum="CB05E4665C90C28D" modified="2023-09-13" version="1">MTPGYFTDLTFATINFSPDTFYVSRFLDRPSYTWADLIGAIGGMASIGLAVWIFLFGNGRYKSWGIMQRYVLRTSPDSKKERDNEAPKTMYQRIRQFLRDMLARFDSSTDDEIDNLPLQSAARKRQSLRFSTNMDTAGGAAAVATGSGKGTKTECGEEYNPRYSIDSHGAASNYYFSDQGAPGSYSLRPLAPIGEGEDDAEEQVSELIRLIDLRIDERMWSLERTLSRYYLDGFRLRNYSIQDGSGGDQFYFSRDSESGANPLDDDAPLQPRFDLNKPTPRIPSPPTSSPRYPPRPRLNQQFEVIDQVLSSQLPAVPRASRPGITEAINSSSPPQSSGQLLSSGFPQRRDMRGTIRRAVERLQSEWPQSHTPESYIPRTQYQSGNGDSTGPTPSGYSSVNINPTDEGNNNPPEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MIL5</accession>
    <name>A0A9P6MIL5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005993</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002957">
        <property type="protein sequence ID" value="KAG0002314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MIL5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0002314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="417" mass="48249" checksum="51AD9A7E49DB129B" modified="2023-09-13" version="1">MDIMESCKVILVFNILEILVMISQYLTSHDMAMTMATCKNLSRQLEPILWKHLKDAGWDELQSRQLSLILEDLKNSGDSSGPFRSNITSLTLPTYDTGYPLSFVEPLLKDHLSNIERLTIPMLDRYGNNDEGDEDPEAIQAMEEAIHGLCPKLQHLTIMFDDSNHDISYLRLFISEFNHGGIGLKSYRAYNQDDDTYFDTLETLIDYHFDTLEEVELIDCVVARSENLQYIFTCCKNLRRFWATPGDGGSVELSFADISREEWVCLEMRELRLNLILDDTNNVSYDKAGVASMAKKAYARIGQLVKLEKLSLGCYFDRYVAAGYQLSRNDLTLKHGFLAELAGLSKLRHFHMFTDFWSKMGKAEVKFIHEHWTCLERITFGEDNIVSRAALDQPHWRWLKEQRPGLIFDYDDYDNYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MKC9</accession>
    <name>A0A9P6MKC9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005273</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002607">
        <property type="protein sequence ID" value="KAG0006470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MKC9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0006470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="219" mass="24974" checksum="77418AA1FC3B668C" modified="2023-09-13" version="1" fragment="single">MTGTHPCDPCGSGTTSIDTPGTVNEIFETADPARKETEKRWRKNPVELARESARQQTYQNSASHVSVIDQGSSQALKDSSNQVLQTIMRLEKPNSTVATYRRKYKMWKKFCDKHYDGDYTVNAVRILEFFKAVVFHKQARKKININVGCNEVVGRAPLDLDIRENEEELERREKQKSSCEQEPAMGDDIIDEDEDDIEEVSWRPVTKLTFIGTAADKTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ML12</accession>
    <name>A0A9P6ML12_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Rhodanese domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005087</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002529">
        <property type="protein sequence ID" value="KAG0006924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ML12"/>
    <dbReference type="OrthoDB" id="25002at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022111">
        <property type="entry name" value="Rhodanese_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040503">
        <property type="entry name" value="TRHO_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001133">
        <property type="entry name" value="PRK00142.1-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43846:SF1">
        <property type="entry name" value="TRNA URIDINE(34) HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43846">
        <property type="entry name" value="UPF0176 PROTEIN YCEA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12368">
        <property type="entry name" value="Rhodanese_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17773">
        <property type="entry name" value="UPF0176_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="141"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0006924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="377" mass="43129" checksum="932BEFDD091BFA0B" modified="2023-09-13" version="1">MRDYVQRTPFPPSKDYITLSFYQFRPIAEEDLIKIQYYFLTDLRAMDIVGRIYVSTEGINAQISCPKDRVEHFKEYYATHWSIFDKIRFNPAMSEGRAFKKLHVRIKKQLVSDGIDNSTFDLYNEPTYLTPEEWHNELTSHSKPLILIDMRNHYESTIGHFENSIRPDVTTFKENIDAMLEICKGKEDQDIYMYCTGGIRCTRSGALLKSNGFKSVKMLQGGVTAYGKYIQEKRESAKKSGISDGNGAEEVKSIYKGKNFTFDKRLGEPITDEVLAKCHTCGAPCDSYCNCSNMACNLLMISCPTCLEKHEGTCGSTSCVDMVKELNAKQKQIDKNHPGLIGMKARPGIKPYHEHRLRVRPLVVMEMRKSKPSSRVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MM66</accession>
    <name>A0A9P6MM66_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_004952</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002474">
        <property type="protein sequence ID" value="KAG0007202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MM66"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0007202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="193" mass="21792" checksum="91298F893FF87CE3" modified="2023-09-13" version="1" fragment="single">KHGEEHVSFPNFMKKFDITDKATANESYSSLIKSPCINKTQQKLQNAYELFLKRFEKKIWERRAVIAQNASVKELSSGFERYRLDSKTIEYSDYKIIDDRDTESETDNRSDAGTKIIFAGPSVSDDSLAANAVPLANDSGSVIVLTINCRLVISEMNKKIMTLDRDLEVALDQWAASFKGNIKEAELIASQQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MM76</accession>
    <name>A0A9P6MM76_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_004950</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002473">
        <property type="protein sequence ID" value="KAG0007204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MM76"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="430"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="465"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="614"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="10"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="156"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="616"/>
            <end position="652"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0007204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="735" mass="80209" checksum="DF0ED70B23E290B8" modified="2023-09-13" version="1">MKPSASPSLSPSPKPPVGPPPSPSVSALAKPPSEPPRNPASPIVYVPATTYSPAASKGKPIVDNKKPAVAPSESPESERATPPRPVPMGFPVVTPLEPHVFKRTPPNAEHSPSLLPSPPPSSSSSPGGSVSTAPSLKNSRPIDVKNIALRANSPDLSRKDNELKNSRPIELGKPSMENAGSWSANPSPSPSPSPAASGTNPPARHHQGFFPVVPAVDAMRAGLSKGRDLEGSGENAQDNRVDPREIRHMPKETTPPPHTYGADKPRVQFDNFYSLSDPYKDLNLDDPSDFFTAVTQSNIETVERMLKTHPYLIQEAIGFWPHPTPILVAARSRHPLETMKVLVRHGAALDRGDHNGTTVLHFVCEQYPNPIEAVTFLTKVGADCNSRDGKKRTPLMVLLQNGHIISTKVLIETMRMLFMFGAQTKVVDQQHRTPLHYAIQHCKEPAPVIELLLKKGAEVNAIDSRKATPMHMVLEKMDNEEIVQMLLLYGADPSIKNGNKRNALCVAAEYLRVMSAWFLLENDLMSSAPETVKKASELCSKADGPDKNSKPLFKNLLSDWQGKEGKLRRIQLAQDCVLRVQRTPDMKTIDQTQVALEFLESAGVPIHISEQDHNNHNNNMNNSNNNNNNSVGNINSNNNGTNNNNNNNHNVSGYALANGPGGNTPGLTFANASYKNNHHHHANGNGHVQVKELRLAEGVEPLKQTMLPVKSVQQLEKEREAIRNQVKFTAMNSAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMB7</accession>
    <name>A0A9P6MMB7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RCC1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_004369</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002231">
        <property type="protein sequence ID" value="KAG0007681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMB7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051553">
        <property type="entry name" value="Ran_GTPase-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058923">
        <property type="entry name" value="RCC1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45982">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45982:SF1">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25390">
        <property type="entry name" value="WD40_RLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00633">
        <property type="entry name" value="RCCNDNSATION"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00626">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="RCC1-like" evidence="4">
        <location>
            <begin position="6"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="28"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="81"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="134"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="188"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="250"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0007681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="304" mass="32270" checksum="2BF01DF37CBE9AC1" modified="2023-09-13" version="1">MPVEGLDDVKIVKVACSDSLTVALTSDGHVYTWGTFRSAEGILGHSKEKEVQELPTIVQGLKGIVDIATGTDHVLALASTGRIYSWGNGQQMQLGRRIVARRMLNGLTPESIGSKGMIKVGAGSYHSFAIDKNGKAFAWGLNTYGQCGNDDPNKDNIPTIAPIAAMKSYICADIQGGEHHTIALTKDGQLYGFGRSDSHQLGLGYTELPGSEDTTSHKKAIRRPTLIPGLPTIEAISVGGNHTLALSTDGDVYAWGFGEMLACGNGEEEDVETPLKLTGQQIENCRVLKVAAGGQHSVILATPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNB4</accession>
    <name>A0A9P6MNB4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Crinkler effector protein N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_003519</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Host cell</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001934">
        <property type="protein sequence ID" value="KAG0008381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNB4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043657">
        <property type="term" value="C:host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045379">
        <property type="entry name" value="Crinkler_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20147">
        <property type="entry name" value="Crinkler"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040169685" description="Crinkler effector protein N-terminal domain-containing protein" evidence="4">
        <location>
            <begin position="20"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="Crinkler effector protein N-terminal" evidence="5">
        <location>
            <begin position="5"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF20147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0008381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="445" mass="49410" checksum="D3633A36690F5C43" modified="2023-09-13" version="1" fragment="single">MTVLLKLFCLVDGESTSNAFELTDIPGTCSVSTLKKLIKAEKTPKFDDIAADELTLWQAFVPVTAATKHDTVLITGIDDKEELLPTDELSDIFGDTPAKKTVHVIVTRPPRVLEPSPSLALAHTFQQSRPSTPLYDQDVSVALAKIATNFFQPESEHTKFLKEFVMGIHHLPVTTSGIKGLPKVGKRGPTKSRKAPTLLFFDLPTPGQSNGQLGMAEQILADNPGLRHLPLFGVSGCGKTRTTVELLSRTWGLYFNAGGKDLGSSDMHTIIEALSDRPDIYLSENKEANTDRVRHLTFGLLYARLLILDYCLGVPESDDTFSCQRWMLLQVANPAFKDIFQGLFQVISRYFREHEVSSFIIDLVQDLFDKVQSQLLQRAESTALGHFKFLLVLDEAQVLGRLADKAFLDSDRTTIRPVLAPILHAFRRIAKKQDEENVCVMPCGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNH3</accession>
    <name>A0A9P6MNH3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ATP-binding cassette sub- A member 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ABCA1_1</name>
        <name evidence="11" type="ORF">BGZ80_003181</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001829">
        <property type="protein sequence ID" value="KAG0008670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNH3"/>
    <dbReference type="OrthoDB" id="8061355at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005319">
        <property type="term" value="F:lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03263">
        <property type="entry name" value="ABC_subfamily_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000665">
        <property type="entry name" value="ABC transporter A family member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026082">
        <property type="entry name" value="ABCA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229:SF205">
        <property type="entry name" value="ABC TRANSPORTER A FAMILY MEMBER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12698">
        <property type="entry name" value="ABC2_membrane_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="251"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="292"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="329"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="362"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="395"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="470"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="574"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="534"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="911"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="911"/>
            <end position="921"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0008670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="930" mass="104481" checksum="DAED00C561841AE4" modified="2023-09-13" version="1">MPSIVETPASQGSGASPKRAVENEFSSNIHVTTGAVQSNSYRDGIAIGFRQLWTMLKRNTILQKADTSRQLKSNYHPEPWTLPGIDNCQGRTPKDPCINVMFTPDTAEIRQILTTANKLNQAREPAVNLNFENAMTDVNTLPSSTLGMVPVPDGQFIYNYTLTNPNVTRFGIEFSIVQGPPKNYAYQTWFNFTNAANSTDPFGDSLLSFTRAIDEAILQIAEGSSATLLATLKDFPLVPPTLASDEVVSSLGAMFFFCSTMVIFICVLNQIVTEKELHLRHSMQMMGLKTLVYWLSWWLSNALLVLVNAVIICGFGIAFGFTVFSNSNFLALLITFFLFGLSMVTMAFWITTMVKASRTAILIGIFLFIIGLLFESMVFSNSYVGYIWYDSGTSVVAKYVLMFIPFFNFGKVFLDMSLFATGRLDILTETYIPGPGFHWSDMYNQIPTSYTPTYNAERTRHPDVPAPIQSWYFMLMNIGVFAILTLYFDQVVADDYGNKRHPFFFLDPSFYGFHFRKKLTGRDWIAAQETDKAKRDSRRKKMNKNHELPCEDEDDDDVNAERLLALDPSFETQARICNLQKIFQESAFRKSPLDKIAVKDLCLTLQEGKLLALLGQNGAGKSTTMNMLSGLTKSTGGDAMFYGLSMNSEMAEIRSMMGVCPQHDILFGDLTAEEHIQLYAGLKNVPKHEIPRLAEERLKAVRLWQVKDKLSHTYSGGMKRRLSMVISTLGDPKIIFLDEPTTGMDPTNRRHVWSFIEKFKQGRIIILTTHSMEEADILGDRICVMAHGRLRAIGNSIHLKNKFGAGYRISLVTDPSNTEFVKSQIESRVPDCILKDDSAGALLYQFPPTSMSSIPRLVEWLENNGVTSTNVHPLIQGYGISQTSLEEVFLKLIRDANPDGYQGYETVKKVVDEKPESESTLRNRGSNNNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNI2</accession>
    <name>A0A9P6MNI2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Methyltransferase type 11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_003543</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001942">
        <property type="protein sequence ID" value="KAG0008358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNI2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0008358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="209" mass="23631" checksum="2170271205299219" modified="2023-09-13" version="1" fragment="single">DMATELTTINFVGVDISPIYPTAIYPRNCNFYNENFLQGVSQPNNVFDVVFQRNVQCGLAPEHWQIAMKEAFRILKPGGYYECVEAELLIHNSGPQTELVFEHLRNSLATRNIDPKIARSMNRMMAAAGFVDINVKEYPVPVGDWGGKVGQLWKQNAFAVLETVRPQLARAARISEAQVQEVVNAMHQETYVYRAYQNVYVAYGRKPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNJ2</accession>
    <name>A0A9P6MNJ2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Signal peptide peptidase-like 2A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">SPPL2A</name>
        <name evidence="9" type="ORF">BGZ80_003144</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase A22B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001813">
        <property type="protein sequence ID" value="KAG0008709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNJ2"/>
    <dbReference type="OrthoDB" id="29661at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098554">
        <property type="term" value="C:cytoplasmic side of endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030660">
        <property type="term" value="C:Golgi-associated vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098553">
        <property type="term" value="C:lumenal side of endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042500">
        <property type="term" value="F:aspartic endopeptidase activity, intramembrane cleaving"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033619">
        <property type="term" value="P:membrane protein proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007369">
        <property type="entry name" value="Peptidase_A22B_SPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006639">
        <property type="entry name" value="Preselin/SPP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12174:SF103">
        <property type="entry name" value="INTRAMEMBRANE PROTEASE (IMPAS) FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12174">
        <property type="entry name" value="SIGNAL PEPTIDE PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04258">
        <property type="entry name" value="Peptidase_A22B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00730">
        <property type="entry name" value="PSN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="88"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="118"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="171"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="302"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="330"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="372"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="372"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0008709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="392" mass="43568" checksum="AF9AB32D7355D8B0" modified="2023-09-13" version="1">MNVGRTLTIIVPHLLSAPLLLLAILAITVLTLSTLASADTTVQERQEQRQKEENGEAVALTKYHAIGFGFTASIGLLAMWMWSNVLVYMSLFTFGLGSFVSIQQCMPGIMKRLGLGRGHLWHHSTIAGLLVVSWFWYRNSSLSWIFQDILGGFTITLMLKVLKASSMSTPTLLLLMAFIYDVFFVFVTPYLTKSGESIMEAAATGAAMTVKETIPMLFRIPSFTPHGGEAMLGFGDVVLPGVLVTFLKECDARLEEDQTLEGLTSSGITRSLPTSCPSSSCSTSSSCSLSCRRSWWKRRWSYHLTAILGYSLGLEVTFVAMLWSNKGQPALLYLVPFTVIPVIFLASKRHELSLLWNGWRDIDDDEMQLDVETDGEEEEQDQQEKQTSTVFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPA4</accession>
    <name>A0A9P6MPA4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="20">Rsc complex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BGZ80_003086</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001799">
        <property type="protein sequence ID" value="KAG0008753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902494">
        <property type="term" value="C:catalytic complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd17996">
        <property type="entry name" value="DEXHc_SMARCA2_SMARCA4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10810:FF:000008">
        <property type="entry name" value="Chromatin structure-remodeling complex subunit snf21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000843">
        <property type="entry name" value="Chromatin structure-remodeling complex subunit snf21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014978">
        <property type="entry name" value="Gln-Leu-Gln_QLQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014012">
        <property type="entry name" value="HSA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029295">
        <property type="entry name" value="SnAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10799">
        <property type="entry name" value="SNF2/RAD54 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07529">
        <property type="entry name" value="HSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08880">
        <property type="entry name" value="QLQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14619">
        <property type="entry name" value="SnAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00573">
        <property type="entry name" value="HSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00951">
        <property type="entry name" value="QLQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01314">
        <property type="entry name" value="SnAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51204">
        <property type="entry name" value="HSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51666">
        <property type="entry name" value="QLQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 10" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="QLQ" evidence="17">
        <location>
            <begin position="121"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="HSA" evidence="16">
        <location>
            <begin position="349"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="14">
        <location>
            <begin position="534"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="15">
        <location>
            <begin position="846"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="domain" description="Bromo" evidence="13">
        <location>
            <begin position="1257"/>
            <end position="1327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="98"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="334"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1157"/>
            <end position="1229"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="1010"/>
            <end position="1044"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="1121"/>
            <end position="1156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="98"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="335"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="18">
        <location>
            <position position="1334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAG0008753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="20">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1334" mass="153710" checksum="40CD6FCCC2D83938" modified="2023-09-13" version="1" fragment="single">MNPAPPQPQAQAISHEMVANLSQEQITSVLGAVRTMKAAGATEQTNSQYAQLMSLLRAYQAAQTQRPAPGLAPYQQQQHILQMQQQQQFHQIQQAQQQQLHQLQQQQPPGAPALPNTQGSPFTQDQITDLRYQIIAFKLISANMTVPPHLQEAIFTPKSVEQALNAKEPTASVAGRVVDVARHHLSEQTPTASDYNAYTSPFSYLQKTLPSAAHASRQQRLLIPSISPVGIDPYALAQERDNRLKSRVKYRIEELDGLPSNIASEALDPSGGLLDQENKVPPSGPKLKALIELKALRLLERQKKLRAEIIKGMSKATMLATSTDRAAYRRMKKQSLREARMTEKLERQQRQDREGREKQKHVDYLQNIVNHGRDMIQWHRTQQMKQNKLGRLVLQFHAHVEKEEAKRIERISKERLKALKNDDEEAYLKLVDQAKDTRIAHLLNQTGSYLSSLAEAVTAQQNDSVHADMTTRGGVEMMDDEKEFEYADGTRDDSKRNDYYNIAHKIQEKITKQPSILTGGTLKEYQMKGLQWMASLYNNRLNGILADEMGLGKTIQTISLVTFLIEAKQQNGPFLILVPLSTLTNWTLEFEKWAPQVTKVVYKGVPSQRKHIQQTEIRHRNFQVLLTTYEYVIKDRPILSKIKWVYLIIDEGHRLKNANSKLFVTLTQHYSSRYRLILTGTPLQNNLPELWALLNMVLPRVFNSAQSFDEWFNTPFANTGGQDKIELNEEEALLIIKRLHKVLRPFLLRRLKKDVESELPDKVERVIRCKMSALQLKLYNQMKKHGMLFTQGGEKGRTGIKGLNNTIMQLRKICNHPYVFEEVERVINPSKTNNDQLWRVAGKFELLDRMLPKLFKTGHRVLIFFQMTAIMNIMEDFLHYRQYQYMRLDGSTKSDDRSALLKQFNAKDSPYFVFLLSTRAGGLGLNLQTADTVIIFDSDWNPHQDLQAQDRAHRIGQTKEVRIFRLVTEKSVEEHILARAQYKLEIDGKVIQAGKFDNKSTAEEQESFLRSLLESDNNKEENDIEEEEMNDEELNEIVARTEEEMNTFRHLDTERKAMDDEAFKKTGVRLERMIQESELPEVYLVDEDVQETVQVEEDLGRGQRVRAETRYDDGLTEEQWLEALEDEDKDVNEIIAQKAERRRKREEKRILKEAALAAGEELEPEPKKGRGRGKKTLRDEDEEEIESAAPKKGRGRGTKSSTSAEITKPAAKGKRGRKPEGASAGQDTLSEAERKALTKAMEQCYKAVEDCTTEEETPRRRCELFLQLPSKKEYPEYYQIIERPIAMDIIKKRMRSAYYKTPAQFREDFHQMFKNARIFNLEGSWIYMDSERLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPC1</accession>
    <name>A0A9P6MPC1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_003152</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001818">
        <property type="protein sequence ID" value="KAG0008698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPC1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0008698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="241" mass="27035" checksum="9C9FEB9CFDA74FAE" modified="2023-09-13" version="1">MNISNTPRPLEVNISFQSENNWTRSHLRAFNITVQPVDADDVPWRRDLIPEAQAFLESNADLGARIYRLAPTLEVPGSTTRFKRKALIYTKMKHIEASVGMMQNLLESVLSDMFEVTPGLPNELRVGNNSTDATSDLAVVHFPIGYQRVIVVKDKLDLSTGAAVPRENAEAQMVAKGIAICQKEGSPRDLPMYMMRVNGSRVNVYMAQFDEPYWTALLREHIVRSIQPCTDLTLPTSLSTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPG5</accession>
    <name>A0A9P6MPG5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_002731</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001689">
        <property type="protein sequence ID" value="KAG0009105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPG5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0009105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="251" mass="27552" checksum="331685E496434F59" modified="2023-09-13" version="1">MDLHRGEIVRLRIKGSKLLSGDSFGEVAVWDTTTYTCEGLIDAGSGSIQLMDFSEAAMIMTVISKSGVIHIRSLIVLTDHHLLHMEWEPLFKSPKNNFIIDTHGELPPNLAKTPSVVRTKIPPISTITSIAIGGKHPRVLIANADRPSLDGAVRVCPPTSRYSTQRSRQKQQPQQEQKDEYLELVEELEMASLSGIPTENVGIVLTSQVEGISDYLKTCGLKPSFMDVDDDVIVIGTSKGDIVVMSMTPQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPH4</accession>
    <name>A0A9P6MPH4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_002718</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001682">
        <property type="protein sequence ID" value="KAG0009125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPH4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047139">
        <property type="entry name" value="ANKZ1/VMS1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16036">
        <property type="entry name" value="ANKYRIN REPEAT AND ZINC FINGER DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16036:SF2">
        <property type="entry name" value="TRNA ENDONUCLEASE ANKZF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0009125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="110" mass="12098" checksum="5A403CB528F26DEE" modified="2023-09-13" version="1" fragment="single">MPQDNPTTASSDVAIPSEPLSIFFLPPELVSSLVPKSQSDGLSLDHSLEPTRTTQSQHVPQSAAVATSLDSTVPSCRVCGISQFDSVEKQREHAKLDWHRYNLKQQLLDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQ24</accession>
    <name>A0A9P6MQ24_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">RING-CH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_002270</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001556">
        <property type="protein sequence ID" value="KAG0009549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQ24"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011016">
        <property type="entry name" value="Znf_RING-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46283">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE MARCH5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12906">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00744">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51292">
        <property type="entry name" value="ZF_RING_CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-CH-type" evidence="9">
        <location>
            <begin position="117"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="66"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="95"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0009549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="258" mass="28320" checksum="511285C99CA1693E" modified="2023-09-13" version="1">MEPTPASSSVQGTAALATMHTSRQSSSSTTGNGTNAGPSNTTNINQKQPLGQGSDPAPGNMAIFLKELETIRETSRSKQQPQQQQQLPPPPPPQQQQQQQQQTPSSQPSPTVTNPTPVYQEPNRCYICFGTEEDSVGRWVKPCQCTLISHEDCLLDWIDKNRQQFAKKQVRCSVCNTVYRLAEPNSMLLNIYSSFDSLVHAGIPYLTFLGLTCSVLITSTTYGAYAVLTVCGTEEGEKLLGSPNPWGWRVWVMRLKAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQU8</accession>
    <name>A0A9P6MQU8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_002376</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001584">
        <property type="protein sequence ID" value="KAG0009448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQU8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0009448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="115" mass="12683" checksum="E90B7F31F152275C" modified="2023-09-13" version="1">MPVRLINTSKEVIEFPTVQEAYDFVLSLETPMSFRTDAPNPVCIPIDPESSPKQLTERTYAILPLTEEEKLMIKKKLRNMVNEMKQGGGIPGMSDADSELITALAQAEAPESTSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MR38</accession>
    <name>A0A9P6MR38_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Terpene synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_001351</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001302">
        <property type="protein sequence ID" value="KAG0010601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MR38"/>
    <dbReference type="OrthoDB" id="2324198at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19086">
        <property type="entry name" value="Terpene_syn_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0010601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="269" mass="31307" checksum="8F17FA957A3CE66A" modified="2023-09-13" version="1">MNTLIESFNKTKQAMTSEKITRAVAELNQYWDELELDHFEHVMDFTNYLSVYCEQLPCPETTYIVLAILFSHYLAIDKFLLRDDNSIVDSIHAKYLSLMSRHLEPEELEYYKYSFKTWAASCHEEAILKQTLPATNTPIARHSMWADWRWVNIGVAPFMRLVMMINFPNENLYSAITQSSIVYISMQCAYLNDVGSVVKDKGSNEVNYYLEVAPGMVGKQSDILEQSNKYLEMVDLSHNLKHVLRSAIHGSYLLYTLSERYFGRTESNW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRI8</accession>
    <name>A0A9P6MRI8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">holo-[acyl-carrier-protein] synthase</fullName>
            <ecNumber evidence="1">2.7.8.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_001086</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.7" evidence="1"/>
    <dbReference type="EMBL" id="JAAAID010001242">
        <property type="protein sequence ID" value="KAG0010916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRI8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008897">
        <property type="term" value="F:holo-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019878">
        <property type="term" value="P:lysine biosynthetic process via aminoadipic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.20">
        <property type="entry name" value="4'-phosphopantetheinyl transferase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008278">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037143">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055066">
        <property type="entry name" value="AASDHPPT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050559">
        <property type="entry name" value="P-Pant_transferase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12215:SF10">
        <property type="entry name" value="L-AMINOADIPATE-SEMIALDEHYDE DEHYDROGENASE-PHOSPHOPANTETHEINYL TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12215">
        <property type="entry name" value="PHOSPHOPANTETHEINE TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22624">
        <property type="entry name" value="AASDHPPT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01648">
        <property type="entry name" value="ACPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56214">
        <property type="entry name" value="4'-phosphopantetheinyl transferase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="4'-phosphopantetheinyl transferase N-terminal" evidence="4">
        <location>
            <begin position="38"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="4'-phosphopantetheinyl transferase" evidence="3">
        <location>
            <begin position="149"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF22624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0010916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="222" mass="25302" checksum="C7883332FCC5CFCE" modified="2023-09-13" version="1" fragment="single">MPIALWAFDIRQELLLENIKPLVTPLIDGNRPNIVPITNLLSFLPKIECDRLLQFRFEDDMRRALIGRLMIHAFFVAHHGCRWDELVFSRSSVISSICPVPNSIRSSNGKTDEIIAEPNHLRGISFNISHHGNWVILAGNTSLENTVRLGIDVMDFQEQFTAKEASFLRDAPSDPNAPDSHLRRFYRLWCLKEAIVKALGVGIDFDLTSFEFTINETVETLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRK3</accession>
    <name>A0A9P6MRK3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_001628</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001376">
        <property type="protein sequence ID" value="KAG0010273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRK3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0010273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="100" mass="11288" checksum="641A21B114C4DA6D" modified="2023-09-13" version="1" fragment="single">MFRNLISPRTTNLSLEDALELANKYLENAHKEVDAAKALELSNKAKSLLKDAKNIFASKRVKDLTLSNGIANAYHEHGRLLDDLGHHEKQRKVILRLRSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MS44</accession>
    <name>A0A9P6MS44_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_000646</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001139">
        <property type="protein sequence ID" value="KAG0011482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MS44"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14008">
        <property type="entry name" value="STKc_LKB1_CaMKK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030616">
        <property type="entry name" value="Aur-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24350">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE IAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="1"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="349"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="439"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="453"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="532"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="564"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="598"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0011482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="632" mass="69333" checksum="8A53D1864D4FBE51" modified="2023-09-13" version="1" fragment="single">LEYMEGGEVRWKDVDDKPILSLEDARAIFRDVVLGLEYLHIQGIIHRDIKPANLLLSGDGTVKISDFGVSHFSEKNALEHDLESSPSMEKGGKGLHAHSHSNPFESFFRHSNPHSPLASTFSGHQELSAATQNHQWGDDVELAKTAGSPAFFAPELCYASEISPAMSPAPSSASRASFILSPPTPRTIPSTPSGTVSAGSGQAYAPRPPITKAIDIWALGVTLYCFVYGRCPFIAETEFELFNMIPRKQPSFPDSVPGRDHVNPSLKNILSRLLEKDVSKRITLKEVKEHPWVTEDLSDPERWRIETDPANYQKVHITDDDLKGAVTIMDKIKNRIRRLSVSLSNLTRRRSKSISSAKTPGGPLYDRIESPSGPRSPIPIMRSPIATISQSTAHAVAQPPTFVSPVSLPERFQHFHSFSNSGANLGRLDRLERPNSVYSNTSSIEEVNEGEDQSGSGSSAQNRTSYLGRRRIMRNSRPQSQPGSYESRPLSGASFLSTSSQRDYSDDQIDQSNGPYSGRPVSWGASFNGMPSARSTQSNQSSLSKSWVYCQPSEVESEGSNCKPLPALPLQQPQPQQEQQPSHRSSLSPSSTLVSDSLQEKADQEYLDNSHESLAKPSAIDPPVAPQDLPTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSF0</accession>
    <name>A0A9P6MSF0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Sit4 phosphatase-associated protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_000298</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SAPS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001058">
        <property type="protein sequence ID" value="KAG0011967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSF0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019903">
        <property type="term" value="F:protein phosphatase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019888">
        <property type="term" value="F:protein phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007587">
        <property type="entry name" value="SAPS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12634:SF8">
        <property type="entry name" value="FIERY MOUNTAIN, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12634">
        <property type="entry name" value="SIT4 YEAST -ASSOCIATING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04499">
        <property type="entry name" value="SAPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="381"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="460"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="724"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="778"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="829"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="974"/>
            <end position="1005"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="417"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="475"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="734"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="778"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="857"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="879"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="894"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="928"/>
            <end position="940"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="941"/>
            <end position="952"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0011967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1005" mass="111105" checksum="EDF4CF972DE8EE95" modified="2023-09-13" version="1">MYWRFGHQNASVIDHLLESSSVSLEELLEQDDLIQECKAQNPRLIEYLRDPTVLQQLLSYITSDDLEDRARFKYPFIACEVIACEVWAIFESALSNIDMLVKFWEFLDRPPPLNPVQASYFAKVIGVFLMKKTSEMLQFIKAQPEVVSKLLLHMSTSSIMDLLLKIISMEESPDGKGTVQWLSGEGLMPWLVNRLDPNNDAEIHSVASQVLLDIIAISQSSHPEQPSIGTNVLIDELKSEVIVDKLVGFMLDRNAPHSTSTLINGVTIFIELIRRNNSDYDVEPLPPNSTEHVREAVDLSDLLKVLASRIEDFKGLLVVPRSVTGPTETSIGRQVPLGFERLKICEMFAELLHCSNMAVLNSRPIISVAPDGTVKVPTVKANEPFIHHSQTVREELAESTEEGDPSKDVDLEMNEPAEAKEVKVEAKTEAKTEQEQPAAKPTQSGAEQLEDATAALGLDDQATPRASPPLAPSTEVASNPATPTNRANGVVKIPVGDFLKMQFVDHQIIPTCFDLFFQFPWNNFLHTVVYDMVHQVFHRPMGDIGRPGIDGTYIPPRSDQGVTEGWNRRLTISIFKDGRLTKRITDAQRLCDFECAQPKGVRLGYMGHLTYIADETVKLLELYSQTSLLPTLYEFIDLEDWWNYVSKVLKETKERDAQVLGGSRPNVMEPHKVGLDDVQDDDFMDDHGDEYGSNSGFLGGDAVVSHEGDTASDQFARYLSQQITNNRPEKFGSSDEDEDDEEGNWIGEYGAETDLERRRAVASGLDDTYGNRHTMDFEDSDEDEGANEDAWNSPWPNTFGDSKVSEFGTTTQFNATLTDWSEDFQDGFTEFKTASSGEDSKDNFGFPPFSVDQPKSTDGTTTATTTNEANPFEDDNFVESASNVVDNSAGTEGLDSKETVQKESTESSKSSGVETNMEPVALAPQVKEAPKIEETAKDSSSKSQDTPLNLGVNTIASTSAPTVNIETVPLVDSGAANLKDTGVTSSDNQSDKTPKDASATTLTDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTC5</accession>
    <name>A0A9P6MTC5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_000440</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001091">
        <property type="protein sequence ID" value="KAG0011766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1216"/>
            <end position="1235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="341"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="439"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="709"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="879"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="272"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="296"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="355"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="441"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="709"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="879"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="907"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="932"/>
            <end position="945"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0011766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1294" mass="142438" checksum="734FAAD852AFE25C" modified="2023-09-13" version="1">MSIPIPGAIDPAQLPQGQDTSTSDLARSHTLPLHTLSPAVHPALPTTSTDLISSNSNNGGTHQPLHINPAYQPSPAEQTLPSQQSVPLSTPTLPTVRVNVDGNPLTPANNESSNINHTISDRSKSLPAPLTNRDRANFTSFNPRSGLSKPMRGVSALGALITASSTAVYTGMTNTVQTKPTTENSKNKRRERSEIRPFYRTVSGFIHPRRSMSYSSIPSPRTSPFLTPIETSSLESNSMESYASEEGNPLDCTAPDDTGQSRELRKGQGFGKSRRKALKMKFRRLQRRRGPRESDDCQDEVTSESDPEADVIANRGDGSRGIGLARKLADGLPTSKAEVLNTDPSLLPPSPQPQTRAISGQSRESPIATVPAYAMVYESGSVRTMPLSVVTKGSSIPAAPVVISEQTSRAFSMPSTPWGEPSRGSSTTRFKEMIKRNVGLSSASPSTPTMPSSTATSPSVVKSNYQPWSAIGDFLISGDDQPSSKFSVSRLTGRRKKSKKIRRRRKGFVGAGLGAGVLGVMARRIIGREDASIDEDDEDATFASMRENPHQHHFRAFIPHLLQPVNEGHPHGGLDPVLEEAPGGQAFDLKTMETQRSPISRALAEARQFDRDPNVLLAELEPLPADFANAFSALTAPPVSAETVPTPNAATTKGWSSMPPSSPALATATGGWGGEGVNGGNTLQTPVTNGMSHSATMPSTISALSVPLLTTQGTPPLSTSPSSSISQPKSVKPDPPELRPLAPRSFLFKSYQHSRFHGRYAYYVFRIRENYIEYGKLPVSLDHACAEYFHEADRTYRELENKAKLWHEERRAALMKREKEFEEVRQTGIRLYGEEDEEAGVFTEVSGNESDASSCYKYDEDITDSRSVFEKLLRVTAETNGPNNLDTDPTKSIPNLDGGFFRRDRSPSSFSNSDAASISSAATTPATSHFGTSERSDDPKCRGRDPSPSLVVESEHGSLGTEVDSHNPLNIPNMTEGVWEQTACPRELAGLEEMQRAIDNAYWRKVERNHYEDSRQQLHGLHLYLSNLTENVEYELYEKTCDIEILKAKRNATLFEIINGDKTNPMWLESPSLKQKDEFLNWIAICLVGRENYMIDIANIQITLLQGKLQTKRAETQQTMRELEVTLRKLNHLDDNAKKLAVTLGRTLDTSEVKNALQPSSVTGLTLAQTVECKIKDVNERIMVCSRIMNAARLNLNRLQYEIELEQRSIRLFRQYKIGIAVVTILVIGTLWLLYNRRDIITMNLFKPAMSPVPLSPLEEASQNLQCKPVMENGLTRLSQSSFEVCRYSDQHDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTN4</accession>
    <name>A0A9P6MTN4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Mitochondrial pyruvate carrier</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">MPC2</name>
        <name evidence="10" type="ORF">BGZ80_011743</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Mediates the uptake of pyruvate into mitochondria.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Mitochondrion inner membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000983">
        <property type="protein sequence ID" value="KAG0012445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTN4"/>
    <dbReference type="OrthoDB" id="869189at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006850">
        <property type="term" value="P:pyruvate import into mitochondria"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005336">
        <property type="entry name" value="MPC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14154">
        <property type="entry name" value="UPF0041 BRAIN PROTEIN 44-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03650">
        <property type="entry name" value="MPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="10" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0012445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="117" mass="12605" checksum="124C1364EE8957A9" modified="2023-09-13" version="1">MSSAASAVSQSAFQKFWNHPAGPKTIHFWAPAAKWALVVAGVGDLSRPAENLSLSQNVALAATGLIWSRYSLVIIPKNYSLFTVNLFVATTGLTQLARIFNYRRGLKAEAKPAVASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUK0</accession>
    <name>A0A9P6MUK0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Component of the SF3b subcomplex of the U2 snRNP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">BUD31</name>
        <name evidence="5" type="ORF">BGZ80_011192</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the BUD31 (G10) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000870">
        <property type="protein sequence ID" value="KAG0013272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUK0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001748">
        <property type="entry name" value="BUD31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018230">
        <property type="entry name" value="BUD31/G10-rel_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19411:SF0">
        <property type="entry name" value="PROTEIN BUD31 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19411">
        <property type="entry name" value="PROTEIN BUD31-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01125">
        <property type="entry name" value="BUD31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00322">
        <property type="entry name" value="G10"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00998">
        <property type="entry name" value="G10_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="163"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="163"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0013272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="186" mass="20934" checksum="FCC55F2CC8880614" modified="2023-09-13" version="1">MPKIKSSRTKRAPEGFDEIEPTLREFQQKMKDGKLINLSTFLSGLLIACIQSENDPHEGKRKIEALWPIFRLHHQRSRYVYELFYKRKAISKELYEYLLKQGYADGNLIAKWKKAGYEKVCCLRCIQPKDTNFGTTCVCRVPRDKLEEGKVVECIHCGCRGCSSGSGASSTGSAAGSKEGSSKTTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUU4</accession>
    <name>A0A9P6MUU4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">Mitochondrial escape protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">YME2_2</name>
        <name evidence="15" type="ORF">BGZ80_010481</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10 11">Plays a role in maintaining the mitochondrial genome and in controlling the mtDNA escape. Involved in the regulation of mtDNA nucleotide structure and number. May have a dispensable role in early maturation of pre-rRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Mitochondrion inner membrane</location>
            <topology evidence="1 11">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the YME2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000732">
        <property type="protein sequence ID" value="KAG0014386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUU4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018850">
        <property type="entry name" value="Mt_escape_2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039627">
        <property type="entry name" value="Yme2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32198">
        <property type="entry name" value="MITOCHONDRIAL ESCAPE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32198:SF2">
        <property type="entry name" value="MITOCHONDRIAL ESCAPE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10443">
        <property type="entry name" value="RNA12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 11" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="RRM" evidence="13">
        <location>
            <begin position="226"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="Mitochondrial escape protein 2 C-terminal" evidence="14">
        <location>
            <begin position="372"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="535"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="552"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="734"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU367108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF10443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0014386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="734" mass="82809" checksum="CA44CEB338632443" modified="2023-09-13" version="1" fragment="single">MYRVAATSEATLRRFYTPTSLYSARHRVLVSSPASSFSCRPRILSTISSPSPARGVRSAPVIPRSTQSIPLIQTRRAPSAVSNRGFTSQKEVALTEEEPLQYGLLYIDNAYPLKMGWWDFRYSLLRPGWKTLERKAKNELVPPEDAMPFHFRVGGIEPSSYTTKEALKEIEGRCELYLQSHGHYMWFNFQKVRAFLVKGTPFLEDMASRYPNKKVRIEYSGDLGIEGLYTLFRKYGKVVDITQLPPVKDMPKQAIVQYQFMRSSTSAKNCLHGSELNGVNINVAFERTLKGNAIWAWLSNHPRISVPLGGFLVAGVSFVIFDPIRVFSMRSKITKLFNVDEYPILRWLRKETVGRLTRSPAEPLQATGWREREKEEEKLRAWLRNPPETFAVVQGPRGSGKTDMVEYAIKDKNHKVIIRCEELANARSEGEILTKLAEQVGYVPLFQFMNNLNNVMDMAITAATGQKAGLSATFEGQMEKILDALTIAIQQISPTGNMSTVAPEAIMKKIEITIKEKMRKAENARKAELAYSSDSLPTENLGSKEVVEDEATNSKEDENHHWCDPDDIPVIVIDGYMSREKGPQAKELWTFLAKWAAVLVENHVAHVIFISNNVSASKPLARALPNMTFETIMLSDATLESAMEFVYKHLDGTKYPALSESVKAIGGRLTDLELFVQKVKSGMDPVDALRDILGRAVIEVRKNAFDFENTDKKSLGWTPIQFWCVMRQLAAEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVN3</accession>
    <name>A0A9P6MVN3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein phosphatase 1L</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PPM1L_2</name>
        <name evidence="3" type="ORF">BGZ80_009885</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000633">
        <property type="protein sequence ID" value="KAG0015390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVN3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832:SF668">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="2">
        <location>
            <begin position="278"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="642"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="87"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="122"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="143"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="647"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="710"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="738"/>
            <end position="751"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0015390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="763" mass="86001" checksum="E0D6169A89C38417" modified="2023-09-13" version="1">MNSTTYYRMTPRALEPTLHINGDDSDATESDTNASTKLLKVTSTSGKGQSTNLKSRSKTAVTTARRKPKQPGSDNAASKNRKRKPASGWTSSSLSSDNSEDDTRQHRASNGRLHAANHSHHQQQPQQQQGQQQQEQKEHEEQQQQQQQQEQLQQSETSAKRIRTGSPSSSTSSAKLPGRRNSIPNGLKKLPKGYVYDTEINQSALMRLSVNPSLTGEYMRHLKGKNALENNFPDRRGEYGVDLAQEPSLFALEQQAGYTYPRLRNSRERLPKGDCEDGYAIADLKHNGGYLGRLFSITDGHGGRACSSFVIATIPGAMQVILGKYKPSDLSLPKVQDLVKTQISEAIRLIDKEYLDYKKQQYLLFKSGQLANDPGSDGTTLIVNIFIDKWIICLNLGDSRTMIGSRDSIGRWNVDFFSEDHTPSLERLAQTIYANGGEFVTHDDKVIKFDPNLKNDKKHRQSLREARIRVKDGESNEFGIPFRTKNGHCASVNLGACIGDVLYKLDPVNPVLSCKPDITFIDISKIQQGFLLMASDGLWDYVQRGGKVHDQNATVCHFVGDKIDRGWNHQRIVYSLSDRENATGLYSDSIQEYDDFTAILVTFNPQQLERQKQQHMEFERKQKLLQQQRAQEQQVLLMHQQRLQHVQSEKDKAEQEQLRREQETKPNVIVEKGDDDTDSDVAKSVPESNAKTRKSRVPLSIKADPTPPTVKKENTRDRSPKSPRSPRSPRSPKSPKSGTKDIKHEIEEPKPVKRKKSLTSPKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWB7</accession>
    <name>A0A9P6MWB7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_009457</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000569">
        <property type="protein sequence ID" value="KAG0016063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWB7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040202922" evidence="1">
        <location>
            <begin position="35"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0016063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="83" mass="8978" checksum="6DB38E31460803CE" modified="2023-09-13" version="1" fragment="single">MIFSTPARSPATVMYMVVLSALALLTTMPLTAQADCTLECAAINTKIVFCGNVKNGFQNTMPVIGVDSQLDNCLCTQENVRLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWK8</accession>
    <name>A0A9P6MWK8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Mitochondrial fission process protein 1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Mitochondrial 18 kDa protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_009369</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MTFP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000554">
        <property type="protein sequence ID" value="KAG0016208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWK8"/>
    <dbReference type="OrthoDB" id="424969at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000266">
        <property type="term" value="P:mitochondrial fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019560">
        <property type="entry name" value="Mitochondrial_18_kDa_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11001">
        <property type="entry name" value="MITOCHONDRIAL FISSION PROCESS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11001:SF2">
        <property type="entry name" value="MITOCHONDRIAL FISSION PROCESS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10558">
        <property type="entry name" value="MTP18"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00029631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0016208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="219" mass="24082" checksum="04C51EE94B30BA26" modified="2023-09-13" version="1">MTTGSSTETPIVRRVAEEIKHEVKEDIRELEQGEIDTVETPARYLAYLARYKNLFIASSRYLAYSSDVGEAFRPVTTPFFVNAMYGVSFAYVGFDVAYEGYKAKLAGSSNDVIGMTILKRGIFQGLASLLLPAVTIHTVVHQSGRLFKNTANATLKKWGPTAIGLCIVPALPAMFDHPVETAVDKVFEMLEGGGGKTLPMNPKDKERVMKAALNKEKIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWL0</accession>
    <name>A0A9P6MWL0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_010083</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000666">
        <property type="protein sequence ID" value="KAG0015035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWL0"/>
    <dbReference type="OrthoDB" id="6499973at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17352">
        <property type="entry name" value="MFS_MCT_SLC16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF284">
        <property type="entry name" value="EG:103B4.3 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="89"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="135"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="162"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="220"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="249"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="299"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="339"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="364"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="390"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="425"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="456"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="5">
        <location>
            <begin position="91"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0015035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="487" mass="52488" checksum="A4EA8864BF0D0A14" modified="2023-09-13" version="1">MVKPNLFHATHESKTSDSSTSSVQEKVAHQHHKRPASSRRSSYESAIQGNGVVLAKNERYDAAHDHGHHSRPVSINATFDDGIVMESGWYGYLVVFGGFLIIMVAIGYVSIYGIFQSQYNDIYGTKGASPSSVSFVGSLAVGFQFGFTIISGPVMNRFGHKVILWSGTIIGSLGLLLASWATELWHLYLTQGVMFGIGVSLLNLAATAIPPLWYAKHRGLAMGICFCGAGIGGLAFGFLIPALINKVDIYWTLRIYAILHFVCTAFASLVMRAPRQLSGPPIDTRKDTINLTILKDPGFIIWLLAATLFGFAYVVPFTYLPSYAKDIVGLDPNVQGGQLLSITSAANAVGRVVIGIAGDRLGAIRVASFSFIAAGASCFIWMFAESFGALIGFSIMYGFFSGAFFTLVASITANIVGLTHLGSGLTVIFLTNTPGNLFTLPIAGTMVEGTIDYKNMIGYNSAMFLSGGVLLCFLMFYNHYTKRIDAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWU7</accession>
    <name>A0A9P6MWU7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Inosine/uridine-preferring nucleoside hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_009694</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IUNH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000603">
        <property type="protein sequence ID" value="KAG0015703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWU7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008477">
        <property type="term" value="F:purine nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006152">
        <property type="term" value="P:purine nucleoside catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.245.10">
        <property type="entry name" value="Ribonucleoside hydrolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001910">
        <property type="entry name" value="Inosine/uridine_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023186">
        <property type="entry name" value="IUNH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036452">
        <property type="entry name" value="Ribo_hydro-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12304:SF56">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G11790)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12304">
        <property type="entry name" value="INOSINE-URIDINE PREFERRING NUCLEOSIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01156">
        <property type="entry name" value="IU_nuc_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53590">
        <property type="entry name" value="Nucleoside hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Inosine/uridine-preferring nucleoside hydrolase" evidence="4">
        <location>
            <begin position="8"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0015703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="317" mass="34967" checksum="4F19788239F15219" modified="2023-09-13" version="1">MTKASPCIIDCDPGIDDTLAILHAMGSPKVDVKAITLTYGNTNRDNVTKNLFTILHILGKEVSSERLATLPAGPNRDRLEHIRSKKPVVSVGASKPLVVSPAYGEDFHGPDGLGRLHLNDPSLAPSDWDDILKTLDPEGLGKELAKAEEPSEKLFTLSRRLAHDEILHQLEQSEPNTLTIIAIGPLNNVALAYEKDPVTFARCKRVICMGGCFDIPGLHYTSMHLHDPLCIGFFMDLENEEDLAKVGWKVEGRDVRIESDGTLTRGMLVVDRRVKSTVPAPGKQSLVQVVLKADPERYLVSMLYDIWGVTDYKGREI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MX40</accession>
    <name>A0A9P6MX40_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Galactose oxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_008613</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000472">
        <property type="protein sequence ID" value="KAG0017100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MX40"/>
    <dbReference type="OrthoDB" id="432528at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093:SF18">
        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040494295" description="Galactose oxidase" evidence="4">
        <location>
            <begin position="33"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="355"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0017100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="445" mass="47831" checksum="1AD79C2C25CF9465" modified="2023-09-13" version="1">MSCRTAKFSYTLSILSYISTVLLCISSTPAFAQTYKPNVKSGSLSAFMDGKAMYVLGGTSGSSQSYSYSAQVFMIDLSIPWNVSSPAYKSLPDAPVGFFQMASALSPDGQTWFAQNGNAAFFYDFESSKWNTIPSTTTGNKTLNSNFGLGAATDPDTGIIYVPNGLVSNGGQYMLKVNPDESIDSAEMSPQMSKTPSSTVAWSAAQRSLIYVDESTGDTFSYSPAKGWNQLAVSGTIPPPRSNACFVGAYGGSKMVLFGGYNATLQTSINTIHILDMSSLTWTSGPTFSSKSGRMGAACAASGDYFIAWGGQSSTSDVDLGASNATLVYDMKNITWTFSYIAPPLPSPSKSKTRAIAISCAVLGTVILMLIAGYIYYRIRSKKPKVIDYLHPPPVAEYYDKSASSIIASVRGREEFEFRRPGVQYYPANPPTYSMTIATPGYRYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXY8</accession>
    <name>A0A9P6MXY8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_007783</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000404">
        <property type="protein sequence ID" value="KAG0017919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXY8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1720.10:FF:000013">
        <property type="entry name" value="Related to multidrug resistance proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001958">
        <property type="entry name" value="Tet-R_TetA/multi-R_MdtG-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF191">
        <property type="entry name" value="VACUOLAR BASIC AMINO ACID TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01035">
        <property type="entry name" value="TCRTETA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="174"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="204"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="240"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="274"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="312"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="347"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="378"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="403"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="51"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="451"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="12"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0017919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="486" mass="52474" checksum="F611FC01ADD14C79" modified="2023-09-13" version="1">MTELDVADALQAEERELTPIESDKDTTARSQPKDVVNSSDVPRGYTDQSRLLPPRELALVFVGLDQTIVSVLIPTLGRVFDAPQYIAWVGTSYLLTNTAMQPLYGKLSDIFGRKNTIVLAIFFFLIGSFICGIAPNITALVIGRGIAGLGAGGMISLTMIIISDVVSLRDRGKYQGIIGAMFGISSVVGPLLGGVLAEKSSWRWAFYLNLPLGVVSTIAMVFILKLPAVTGTHREKLMRVDFLGSFTIVIGVICVLLSTNWGGNEYGWGSAQVVAPYCVGALFLAAFLYAEAFIAVEPILPFRLFRNQSVCATFATSFFIGGSFMGTVFYCPLYFQLVRHESATRAGIQLLPLVAGMLVSSIGNGIMISKTGHYRPFIWGALSIYIAGIALVSLWSLESGLNVQIGFLFVVGLGLGGCLQSIAWPSLALISSLFIRHHVLRKNLGVQEAQGDKVEESMEESPGHDTTLVSSHDIEKGNEVKKFGPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MY70</accession>
    <name>A0A9P6MY70_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Nickel/cobalt efflux system</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_008144</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the NiCoT transporter (TC 2.A.52) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000433">
        <property type="protein sequence ID" value="KAG0017580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MY70"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015099">
        <property type="term" value="F:nickel cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004688">
        <property type="entry name" value="Ni/Co_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011541">
        <property type="entry name" value="Ni/Co_transpt_high_affinity"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31611">
        <property type="entry name" value="HIGH-AFFINITY NICKEL TRANSPORT PROTEIN NIC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31611:SF0">
        <property type="entry name" value="HIGH-AFFINITY NICKEL TRANSPORT PROTEIN NIC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03824">
        <property type="entry name" value="NicO"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0533">Nickel</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="93"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="133"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="254"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="281"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="324"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="371"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="187"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="207"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0017580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="419" mass="45723" checksum="E8347F45CD5CC3F7" modified="2023-09-13" version="1">MNDSIFSHRALRRKSLFVIGGLVLVNIVVWVLAAITAKKYPSMLGSMVIAYTLGLRHAVDADHLAAIDNVTRKLMYQESIKSRIEGQELAPPVCVGLFFSLGHSTIVVVASVVIAATAAAIEDKFEAFGATGGIIGTSVSSAFLFLIGFINLVVLIQVAQELRSVHRTGEYRYRDPVKQMVVGATADDTMDDDNNNHSNNNNNKAVSEIDSKTDDDTNAKNGTNNSRFQSGGLFARIFRPLFNLIDRSWKMYPLGVLFGLGFDTATEVGLLGIAATHAEAGFPTAVILIFPALFTVAMSLIDTLDGIIMANAYGWAFVNPVKKLWYNFVVTLMGVIVAFVVGIAELLGLLAAELNLDGPFWNFFTMLSNNFGLIGYIIVGLFAFTWIFAVLFYKYGPIKGLEDRVIIVEEGEHSEKDVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYC8</accession>
    <name>A0A9P6MYC8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Negative regulator of mitotic exit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">KEL2_3</name>
        <name evidence="3" type="ORF">BGZ80_008446</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000458">
        <property type="protein sequence ID" value="KAG0017284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYC8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="674"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="757"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="896"/>
            <end position="1001"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="91"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="189"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="348"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="441"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="494"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="575"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="674"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="687"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="770"/>
            <end position="807"/>
        </location>
    </feature>
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        <location>
            <begin position="896"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="917"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="939"/>
            <end position="952"/>
        </location>
    </feature>
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        <location>
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            <end position="968"/>
        </location>
    </feature>
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        <location>
            <begin position="970"/>
            <end position="989"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0017284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1001" mass="113246" checksum="45E42CBA20AFC25C" modified="2023-09-13" version="1">MIDLERELENGELEGQHLKITKALIRVKEELRNAKMSIATQAQTASSKIKEAERIRTGALQEAAYLKAKLSSLTNAQQDPDALARVETERAVDLEKRLTGALSELESLESKLTKAQEALEQEKISRLSAEERSQGSSLLADQAQSAHTRALAELATLHARATKAETESREYAAQLAEAQAGSTGHQSQSSNLLQKIKSLKQQVEEHEKALEKVQMAYSAANDRAIRAEAQSDEASQKIEKLESERYELSSEASRYKDEAGRLHSKVDELENRLQVSKDEVTTLRKLVEDGLGAFSPRMKAEKGPERKHDSIAILNTVSKVSELEHELGSLKKLHSLSKESASRSATELAEARIQVSRLEQSSMQARAETISLQKMLSQEREGSSQLKSELNRIQLELDAKVKELEDHEVQLGLLKDVMREKGIIAEDVVMQARERSMPGYTASMEEKVRDAEERAHKLQMEIEESRSHYAQQLEKFENQRHATIQHAEKSGILLRKLKDDLGATMREKDEVERELRQLQEEHARCDDYVQQQVSQKEKEEEQVSMLTMRWDEERRDLKSQLSSLQSRLVESEMHSAELSQKVISVTERLQEVENLNEVIADELEALQDETKDFKSKAASQEEQLKADVERLVSEIHQTQEKLHAKQIELDEAFELNEQLGSQLDHALQAQAAAVTSQSDRSSAATQKVEEQRQDLERRLKKAQETIRALERDNSELEGRLAESEKKVALLLEDMHGVASDPNSPLNSANLAGLHQQLDNHLNNGGDEMSVSDSTHISSLNLNSHQSSPATSTNRLVVKNGNNTSSNRSSPSGGGATSSLTSSVYQSSKSAVASNNNYMQSYDQSEHQQQLGQHGNDYSEDEYVYNQQRNHFYQHEHDSVDSITRELELLKVPWNKNTPAFKSTTVPQEQTQRQNAPAQSQQAYQYSGKYNDHNNQFYDYNDDESSDGDNEEEYLAHLRQQNEQQGKSQQHSKDTHSFDDRSPSRLKEYEQMIDEIENTRLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYG0</accession>
    <name>A0A9P6MYG0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BGZ80_008149</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the YIF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000433">
        <property type="protein sequence ID" value="KAG0017585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYG0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030134">
        <property type="term" value="C:COPII-coated ER to Golgi transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005793">
        <property type="term" value="C:endoplasmic reticulum-Golgi intermediate compartment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005578">
        <property type="entry name" value="Yif1_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14083">
        <property type="entry name" value="YIP1 INTERACTING FACTOR HOMOLOG YIF1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14083:SF0">
        <property type="entry name" value="YIP1D-INTERACTING FACTOR 1, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03878">
        <property type="entry name" value="YIF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="263"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="295"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="329"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="354"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="395"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="63"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="101"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0017585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="414" mass="47480" checksum="25E170543ED806D6" modified="2023-09-13" version="1">MNPYSTSGHNAQYQQQQQYQQPQQQQQQQQGSYYTSNKYNPNAYQPQPAQQQQQYQPRNHMGSPPPLQHPVPTHPPVQMRDPAPTPSPRMPYAQTQGGQGQPYQQNQYRPQQQQQQQRSSFDQQHQQQQPYGGSPQTQFMSSQQHFQPQHHQQQQPQQQQQQHGIPSFPFNLNDGTTQLGMQFGKSAVMAGQEYVEQNLNRWVNRAALQPYFNVSNQYVVNKLKLLIFPWRHKLWTRALKRSETTGESIGYLSPRDDINAPDMYIPVMAFVTYVLLIGISMGTTNNFRPDILGPTASSALAVILLEFTMIKLCIYLLNITSEVPILDLLAYSGYKFVGIIVSIIVQLAKAPKSVFWFVFLYTGAATGFFLLRSLRYVILPEASAGTVQAPQRKRRIHFLICLSVLQFGFMWILV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYK2</accession>
    <name>A0A9P6MYK2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007206</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000365">
        <property type="protein sequence ID" value="KAG0018408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="435"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="572"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="815"/>
            <end position="1729"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1791"/>
            <end position="1847"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="62"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="151"/>
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    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
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            <begin position="179"/>
            <end position="189"/>
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    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
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            <begin position="190"/>
            <end position="200"/>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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            <begin position="227"/>
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    <feature type="compositionally biased region" description="Gly residues" evidence="1">
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            <begin position="239"/>
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    <feature type="compositionally biased region" description="Gly residues" evidence="1">
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    </feature>
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    </feature>
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    </feature>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1373"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1404"/>
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    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1446"/>
            <end position="1521"/>
        </location>
    </feature>
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        <location>
            <begin position="1541"/>
            <end position="1563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1587"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1600"/>
            <end position="1615"/>
        </location>
    </feature>
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        <location>
            <begin position="1643"/>
            <end position="1652"/>
        </location>
    </feature>
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            <begin position="1662"/>
            <end position="1672"/>
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    </feature>
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        <location>
            <begin position="1673"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1794"/>
            <end position="1812"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1835"/>
            <end position="1847"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0018408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1847" mass="191558" checksum="6FA5ACB4AECC1CA6" modified="2023-09-13" version="1">MPDRARIGISSAGGISERTLKSRLGDLKSKNGTSATGQNLDCEHLPQCVETTGGHMVDDTDPLSPTSSLLRRTFRRRSGVGSLLEAPLPPRKEHQRPEQQTRSLPAQRATEDESALPSPDHSQSSSSSVSLSPTPVDVDKDSGFERHRDTEEPLDDSSDACKIHSNDNGSNYPEGVVLSSSGRGNTRGRSSGRSRSRARATRAGSSGTRVTRESQRAQSGGQSGRNGDGDRGDGRDSNGDGGNSGGDGNGGGDVTTAAAFASAAASSASAAAASAQAASTSLVSTAASSSTAAAHSAHAAAQLTSIFVQTAHSDAATAGNVTSPVAAARSAVTAAAAAVVAASRTTGPYTRGPAASPATPAVPAPAAVITAGSASGPSVLSPSVVGSAAAPTITTMPVAPLVSTLSVAPMGATALTPALSPAQIQLQVQQQLSTAQAQTRGQPTQFPAQAPVQNQAQVPQSQQTMLDLLEDAHAYGVLDTSTLRTCYPDAVLQLDQSIPNHITRFHRLESLASLYGLGQLQGSVAVASPGNFLSIAQAQAHARVQAQTNILIAQQQLLAQTLAQRQLRAGLGLQSSSSGPGPGGPGGLGVPGGPGPGGPNGSDGSRSGSGSGRSQGPGPGPNSSSGSDSSSNAGPSLGPVQQPGSQSNNPGPNHAPDNTGSSSGLGSAQIQDPTLGPTTRATLASSAHAATAIPGGSVSSQANVPPVSGSAARNPTEDSQASASSSTLQSHSPTRSALLQTVLQSSNRIPGRPETPSMRRSGPRHTSDGDDGARLAPGPGVGYSSSSMTSTYSSPRQSPLQASFNSYRYVLFFDPTEAPQQTSPSNAAPLHQTEQFRHRERRSEQRTRDETHPHVRSRSQPNRNVQRLIERQVQMPRQRSRVHNDIQEGDGQSDGSGFEADDDDDGGSTGESDGNGNEGNGGCDGGGNKDSSSSPSPDSSHNTIGGSSSYGNGSHSHTQANGSSQGTGSQSRRNPPSGSQQCSSTEIDVIVKETSESAQPSGNQVDVKGVEAEEGQGGSDGTSGLGDGSDSAKRDDDNAEDNKEEDDDEAKDKEQQGRSDSDNDRGGESNDDNDDSSDGGRGGSDSNDDSNDSNNDSGDDDRGGDGSSDDSDDSNDSDYEPSDDSDDSDDSEGDDNGGSDADNGSEASGDGEDEDDGERHDADENKACKTGDVASVAIGSSDASEGSTPDIISSQSDEPCTSSKATLETSLEQTNPKRPRELDFLEGFTSGCSSRESKRLRTTEPVPEKEVQILRYDEKEQDEGSKKELDEELKGEQDKKPKGTEKATQPIEGSNNSQNATQPSPKGSKTSSDESNVPPKASDRSPRESKKSPKESSKLPKESNKSLKEPNKPLESGKSLDKPSKPLEGSSKSLDESSKSRDESKPKKGSRRSPKAPKNESSLDPERQPRREPSVEPAESHKEKKQSQESAKASKKISSECPKTLTKKDSEKELEGEASKKLEPREPRKESEKGSKKVSEKSSKRESENSKKEPEKGPKKDTKTERNKEPKKASKRNESGKATDPQEDNVVRISKPKVVATSKTLPSDSVCQSKSSMGILSSTKPPPDQGKKSSTIGSKSPKDLKTKTVSTKAEASTATTDEKDGSSDTDEHSEADSGNDSTEDKSSSQCTASPLDSPIRSEDTDDSSEDDSREDKDKFEISQKTAASNDVTPSSSPSQGPSSSESGPGISSLATGIATPEAIDSTSEGTNDDDLAMKGTKRKRGHGKIEAVAHQAYSTDNMRLSLPCGPSTTLAPAPTSLSFNPSTMAVPFGQAASGSFTFSAAISSARESRTQPNFGTTAVTFTPSQKPLESTDLYDSDVEMDVQKHAGLSKGKGKKPPTKKYKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYN2</accession>
    <name>A0A9P6MYN2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Gem-associated protein 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">GEMIN5</name>
        <name evidence="6" type="ORF">BGZ80_006718</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000333">
        <property type="protein sequence ID" value="KAG0018801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032797">
        <property type="term" value="C:SMN complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003730">
        <property type="term" value="F:mRNA 3'-UTR binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000387">
        <property type="term" value="P:spliceosomal snRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052640">
        <property type="entry name" value="Gemin-5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056421">
        <property type="entry name" value="TPR_GEMI5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46362">
        <property type="entry name" value="GEM-ASSOCIATED PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46362:SF1">
        <property type="entry name" value="GEM-ASSOCIATED PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23774">
        <property type="entry name" value="TPR_GEMI5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="162"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="736"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="domain" description="Gem-associated protein 5 TPR" evidence="5">
        <location>
            <begin position="1128"/>
            <end position="1235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="836"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1001"/>
            <end position="1043"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="836"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1001"/>
            <end position="1013"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1018"/>
            <end position="1029"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1033"/>
            <end position="1043"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF23774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0018801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1390" mass="153565" checksum="A7E11E86532F502E" modified="2023-09-13" version="1">MDTAFPPSPQWHQPHSACLFCISEDAGWLLYSLNSSIHILNPFTLKYEGIMDNGHTAKINAIAPRPPSGAELKHLKGVSTRPIDDHNCETDNRAFKATLSPNNLEVEPSQCPPKSTENTGPRKALIASVGDDLKAICWDITTRRAIATSKKAHQKAIKAVEWTGDGNYIVSELLDQNYTLLASGSADQTIRVWNVEKETSNHVINVPEMEKKQASYQRSNTWVPVAWTSKGQEIVSCTSRGTMVRWSLDRDTRSFTKVIKGKVHNRIVYQVMTWPLGDFAFTISMDRKIIAWDMESGQGVAQIECIGGNVYTLDISLLDPGRIVMGLGNEAIKVWNTLSQDEPYESVVMERLQSRVRAVKWHPAEEEKICYGLENGKIGMVEDILGTTSNQSQKQGKKGKHGAQAKNKICQRQTIFQSYHEGAIVSMAWCTPKVFEAPVPELFDLSLRDSSYCIVSCGVDGKILVTDSTKPTSKSLDLDVVLQRQNSAWYQSYRAIKGIGAPGRRDFAIHPSEELIAIGNDDGSVEVYELQYFKLVYVYQGHGKRVNRVKWNWLGAEASAEHEGNTIARYLLASGSDDGSIAIHRLDGFSAKAIAERRQRERQAATEKQQDTLAVENEEGTLISPSAGDTSIILPTRRVFAYFSYHARGVSDLTWSPHDTSNGPSSASQQKLVSVSYDGKAIVYELQLDDGHEGEIQVGQIATECDRDEQGTAMRVSEETTTPRSVARQHKVLACFSRHEGQILSVHWSMSDVDRIYSGGNDWRVCYWDWKSHTITDTQLEKLRKDSAGSNLQNAAKVPSSTTVKATFQVPSMPPGNLPSTNDQQLEASLVAVTEDTPQSSNGGISERQNSGHVAQRTAMVDEASLPMKRGSEVSSKNEPMMQKRARTGRSNVNNAAIQPPLGNPTATPLSSVSGISTKCVNLFPSSSATFRFQTKEKVHLEIIRLTRNLYCRRLGQGGILISEEEHAAARERWRAMLNFFEKDKDEDGRAISSILGSDVDEMNLDDNEDDGDIGNYNGPTKSTLNSASLAGGDKRESGVKDQDIDTSIDDSAAANSDLIFYGSRESIKALAEMEAQEVVKVHSGTSQTQHHSNVFAVGSGLGVLPVSVYKDVGLTAEKHSRKIAQLGQIPVNFWMGDVQRMVDILSSLSENELGVQDWIGIALSPMGGVAAWREMMSRTAMKFEKRGEVHASALCYLGIGRVFEAVDVYRKQELYREALMLLRIRLWEDEDEEAGDVGHEKERVAASTNTFKDISQESAEGLQLAAATKTLTDLHIQILTEWGQQLERRSSFEQACKCQLTLAAALRRKMQRNSSIGRHPDRAEVMQATPSVGLQTLARRGDIATLRTVAGLAILLGDPSRQERVARYESALAHHKKLEKGSGVTENSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZH5</accession>
    <name>A0A9P6MZH5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Farnesyl pyrophosphate synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ERG20</name>
        <name evidence="11" type="ORF">BGZ80_005454</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Isoprenoid biosynthesis; farnesyl diphosphate biosynthesis; farnesyl diphosphate from geranyl diphosphate and isopentenyl diphosphate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Isoprenoid biosynthesis; geranyl diphosphate biosynthesis; geranyl diphosphate from dimethylallyl diphosphate and isopentenyl diphosphate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the FPP/GGPP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000269">
        <property type="protein sequence ID" value="KAG0019657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZH5"/>
    <dbReference type="OrthoDB" id="10257492at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004337">
        <property type="term" value="F:(2E,6E)-farnesyl diphosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004161">
        <property type="term" value="F:dimethylallyltranstransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045337">
        <property type="term" value="P:farnesyl diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00685">
        <property type="entry name" value="Trans_IPPS_HT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.600.10:FF:000006">
        <property type="entry name" value="Farnesyl pyrophosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039702">
        <property type="entry name" value="FPS1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11525:SF0">
        <property type="entry name" value="FARNESYL PYROPHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11525">
        <property type="entry name" value="FARNESYL-PYROPHOSPHATE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00005">
        <property type="entry name" value="Isoprenoid_Synthase_Type_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01017">
        <property type="entry name" value="Polyprenyl_Transferase_Like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00723">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00444">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0019657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="375" mass="43410" checksum="9D20C97CAA0AF7EE" modified="2023-09-13" version="1">MTDNTPLLFRTRKPVVINPTPSYSKVYDPTMSNPIKEFMDVFPVIAEELLAHLRSLNIPQNAIEWFDRSMRYNVLGGKMNRGLTVAETLRILKRGEPLSEEEIFKANLLGWCIEWLQAFFLVSDDIMDDSKTRRGQPCWFRVEGVGNIAINDAFILESAIYFFLKKHFRKDSYYVDLIELFHETTYQTELGQLLDLITAPEDNVDLNKFSIEKHSFIVIYKTAYYSFYLPVALAMHMAGVKDEAAFKQAEAILLPLGEYFQVQDDYLDCYGNPETIGKIGTDIEDNKCSWLINQALDIASAEQRKILDENYGKRNEANVKAVKEVYVELGIEGRFKAYEEESYVRINALIEKVDHPLLSQDVFTSFMKRIYKRTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N065</accession>
    <name>A0A9P6N065_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004424</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000226">
        <property type="protein sequence ID" value="KAG0020299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N065"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="257"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="280"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="349"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="375"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="385"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="407"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="442"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0020299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="667" mass="73897" checksum="5D9C335687DEDC19" modified="2023-09-13" version="1">MRLTLEEIESYNLSSAERIKIFHLHHAIVTEVRDNRNWDSALKLFTTYLAPIIVASQKAVAAAAAAAAAGDTVAAVPRSNNSRKYPPESSRMIDFDEKHNSNCKKQLNDEDVRLIQYAISAMVRYAPSVTESNILYMFYLNCQPPIRCDEAIDKCLVSLIYQYANSDQEHQAKGKDLIEVALNRGIGLPEYKSVASRKHKMLGVKPQNDTGILRNVSEPILRLLKLRISSDGRSLEPYDWPPRRSRPPQHTPHRPNQPQSTQQQNQPQPPQQPSQPQPPQQQRQSRPPQQQQQQQQQQQQQQQQQHRGPQQQHHGPQQQHHGPQQQHRGPQQQSQSRQHQYQSHSQPSLPRTESFQGQNEGLGRKNMPTQASVRKSPETNEPHVGRGSLGQLSSLPQQQQEKGEPNTIVSKNINLESGTSGNPASRIPDDDQYGYYQKASRRGFEGSHRDGHRGGHNSFIGSSGGKHRKIAFVPASTNPMLKTDSLPTEDLSEVKESIQAPDAKVPATAIVDATEEELPEESQGSSLATSDIPKEEHLEEGQDISPVLAEKLSEESQGSSLATSDVPKEEHLEEGQDTSSTLAEKLPDKSQGSSLAASDIPKEDHSEESQDISPALAENLPEESQSSSLAASDIPKEEHLEDGQDISSALAEKLQLGSQSCDETSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0R7</accession>
    <name>A0A9P6N0R7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Mitochondrial cardiolipin hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_003316</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the phospholipase D family. MitoPLD/Zucchini subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000187">
        <property type="protein sequence ID" value="KAG0020951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0R7"/>
    <dbReference type="OrthoDB" id="5205528at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016891">
        <property type="term" value="F:RNA endonuclease activity producing 5'-phosphomonoesters, hydrolytic mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09171">
        <property type="entry name" value="PLDc_vPLD6_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.870.10">
        <property type="entry name" value="Endonuclease Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025202">
        <property type="entry name" value="PLD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051406">
        <property type="entry name" value="PLD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43856">
        <property type="entry name" value="CARDIOLIPIN HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43856:SF1">
        <property type="entry name" value="MITOCHONDRIAL CARDIOLIPIN HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13091">
        <property type="entry name" value="PLDc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00155">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56024">
        <property type="entry name" value="Phospholipase D/nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="3" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PLD phosphodiesterase" evidence="6">
        <location>
            <begin position="146"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00040549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0020951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="210" mass="23774" checksum="1347B075B77C0CD6" modified="2023-09-13" version="1">MSHSFAAAVGSNASSPLAQLFENARDSASSEQDRDVISKLESAVMDKLRQETQPHHTGGEVFVSPVFFPSEDSFHHLINTLNKAERSLDICVYCITDDQLASAIIRAHERGVRVRIISDDEKADDLGSDAKRLAEHEQIPVRLDGSPSYMHHKYAIIDDELVLFGSYNWTKGARFHNREDLTLTNSQNAVQSFKREFEKLWREFAPNELE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N139</accession>
    <name>A0A9P6N139_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RNI-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004894</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000245">
        <property type="protein sequence ID" value="KAG0020022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N139"/>
    <dbReference type="OrthoDB" id="550575at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="259"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="312"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="325"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0020022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="489" mass="54619" checksum="C3D8A02D7D02CF79" modified="2023-09-13" version="1">MPNLVDLEATWMNVDLLESLPYLQNLERLTISRLQGSHSEDNTYFEPSFEGSRWIRELSMTDSGQMTDRALVSITQACPGIQVLIVSGNRCLTQDGLIEWCHRLTLKAKDSGSLSTFDSLTLGTNPHPPTTTTELTTINFKNCGRIGSAGFKALFERSHHLEHVNLMSTWVEDDALEVLAAQNKGLQIINLNCCPAISDQGLKNLLRTCTKLRTMSFLSCNRVTAQVFFQGLWRCLGLEELRFSLARWHLNLIENGPSGAPVQQHSDNVNPSVSQDDGQGETQESPQALLNALTNNNQPTFYEPQLELMIFGGPEPENADDDKPSNITDNTSNNNGGDSFASSINTTPMLNLESVETSLHAYAASSTTLQEYRQRLILAQIYRQIERLTFLQILDIRDLRLPLDLASGLGRLGGLERLKTLEITGLESPMGEPEVNWLIGPGLEQDSHVRKVHPLPSLRQLAFKKGQGIPKEYLHRLKEYRPHLEVECS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N198</accession>
    <name>A0A9P6N198_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004209</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000217">
        <property type="protein sequence ID" value="KAG0020433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N198"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055334">
        <property type="entry name" value="PEX8-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39214">
        <property type="entry name" value="MICROBODY (PEROXISOME) BIOGENESIS PROTEIN PEROXIN 8 (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39214:SF1">
        <property type="entry name" value="MICROBODY (PEROXISOME) BIOGENESIS PROTEIN PEROXIN 8 (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1088"/>
            <end position="1111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0020433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1111" mass="124072" checksum="DE943F81424A70EB" modified="2023-09-13" version="1">MVEPQITFLTELLDSIPHASERPRPQGIQAIQRWTRLIVNLILHPSQWNKLGFAVQWAKWIEWEGGLDLKSPVRSPGILYLQNPLHPFALNNLLNQLNFSLVDTETLVGCVDTGDWTCLLKEEEQPDPKMREQAIQSLEHLCLLSFYLRSGLASLSRQSSLNVATDPKEQSDDHLVQDLVSRIMNNQTTTTTTTPRNPIWRQAFSDQALRLTAQQDPNNALLAVSDKLSDAEFQQLGKLLSTSFFTIIEFANVSLFLSVENIAFLSKFAAQLPASWYSDEFLRTTIQMAKRYLSTEQLEKVRIPFQVQGLVAVTTLWSYWMRKTGSGDVNILGQELIEIMAEILATPSLFIGTESKGLFGACFSGLATGLDKWSGLMEPKIIQGMVSALEHGRVSAQDTDLDGIQASLATVLRSNVLDKSPESIKKLIKTFLEVFYSSSEELVLPAAATNVDELLQVQRLFQFVVTYKAGLLPVKDGEDTKKKKKRGKPKKAINLKGLTWFEALIHGVQDISTRGALSSLLAVAGVLRAIQHAEDDPPKVDAESLALVQDLFVAKLNGFTEASKTGGSVSMLSSRTQACIVFITSQTIPNLPSCKLEALDCSLLANLLVEYILQPNEGVVPVSEILRVITYETSQERNRLLLTGAAHQLLNKTVKGPIFPEMGRVARAVATLVEKMENWREIEDLLQRMHSFAINIHVDWSRCGLSKVDSFLERKDGEPGLDSDTTKTMGMLFQVFKTILFAYTMIFGSISEKVSSTTVSAGLISNLDYLMLDSYAYLYFITYRLSPGGFQVYEELITSILTRMVTSEELTAAQQQQILRQNGRDDNINRHILLNNTVKSMMPRAELGFYDPVMESRALFFMNLLERLMAAIEEDFLEQHLLPLVYPYLLKNDQRDLFESSHSVVMAVFLTNKKIAKQVAPFYSNLLLQHFPDQINIDQLRAAFTTMIRSLSETEDALAWLCVEKLLERIQYYDDLAEAEMKSLSEEAAASQSEKTTTSKSLAALERQKQRGELLLALFDQLSSLNLVFVETLGEKIRGLVAKEQSLVGRKALLKCILDVVGGSAVDHTKRDWAVKWYLGLVNEFGHSLPSPSSSSPTSVSTSNSLTTASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1E9</accession>
    <name>A0A9P6N1E9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Tr-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_004672</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000236">
        <property type="protein sequence ID" value="KAG0020167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1E9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04165">
        <property type="entry name" value="GTPBP1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03694">
        <property type="entry name" value="GTPBP_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03708">
        <property type="entry name" value="GTPBP_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000014">
        <property type="entry name" value="Probable GTP-binding protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000091">
        <property type="entry name" value="Probable GTP-binding protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050055">
        <property type="entry name" value="EF-Tu_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035531">
        <property type="entry name" value="GTPBP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004160">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721">
        <property type="entry name" value="ELONGATION FACTOR TU-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721:SF9">
        <property type="entry name" value="GTP-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03143">
        <property type="entry name" value="GTP_EFTU_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="7">
        <location>
            <begin position="221"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0020167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="647" mass="69441" checksum="C8F7BD754A807583" modified="2023-09-13" version="1">MLKKDQLKDGNRSAEQSIPDPADGSTTVQLADKLGSLTLNASSSAAAAAAAPGATPLDDFDINDMDDPLAGFEAQRSGIKDLSLKEQFLNPTDSNIESLQTLLAGRIREGSGETLFEIGIEEDGAPMNLTDEEYQTALSTVRTAATAVGAEIAVMYEQIPGALPVPAPDSKAVSPPAEAVSPLAEAVSASSAAPTAEGDQAATFRRSYVMIRKIPKSVEELLEIRVAVVGNVDAGKSTLLGVLTKGVLDDGRGKARVNLFRHKHEIDSGRTSSVGMEILGFDAKSQPVPTMSHGRNAPWDEICGKAAKVLSFIDLAGHERYLKVNPKKFIFVAICNESCAPDFVMLMVGSNAGIVGMTKEHLGLSLALGVPVLVVITKIDMCPPNVLESTVKQLTKILKSAGCRKIPMFVKSHEDVVVTAGNFVSERICPIFQVSNVTGEGLDLLKNFLNVLPISRKYNKDEPVEYQITDTFSVPFVGTVVSGVVMNGIVHAGDQLYLGPDGNGAFQMVTVKSIQRKRLNVPLACAGQSASFGLKKVRRSTIRKGMVMLDKETTPPPRGCREFEAEILVLYHSTTIGHKYQAMLHCGAVRQTARVLAMDKPDQILRTGDRATVRFQFLQPAYLKVGARLIFREGRTKGIGKVSKIVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N238</accession>
    <name>A0A9P6N238_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_003592</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Su(H) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000196">
        <property type="protein sequence ID" value="KAG0020796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N238"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1450">
        <property type="entry name" value="LAG1, DNA binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015350">
        <property type="entry name" value="Beta-trefoil_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036358">
        <property type="entry name" value="BTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040159">
        <property type="entry name" value="CLS_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008967">
        <property type="entry name" value="p53-like_TF_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015351">
        <property type="entry name" value="RBP-J/Cbf11/Cbf12_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037095">
        <property type="entry name" value="RBP-J/Cbf11_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10665">
        <property type="entry name" value="RECOMBINING BINDING PROTEIN SUPPRESSOR OF HAIRLESS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09270">
        <property type="entry name" value="BTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09271">
        <property type="entry name" value="LAG1-DNAbind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01268">
        <property type="entry name" value="BTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01267">
        <property type="entry name" value="LAG1_DNAbind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110217">
        <property type="entry name" value="DNA-binding protein LAG-1 (CSL)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49417">
        <property type="entry name" value="p53-like transcription factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RBP-J/Cbf11/Cbf12 DNA binding" evidence="8">
        <location>
            <begin position="525"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-trefoil DNA-binding" evidence="9">
        <location>
            <begin position="664"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="134"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="233"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="742"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1088"/>
            <end position="1159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="43"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="76"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="103"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="138"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="270"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="306"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="343"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="387"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="449"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="476"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="499"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="746"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="781"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="1088"/>
            <end position="1105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1108"/>
            <end position="1122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1143"/>
            <end position="1152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0020796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1229" mass="138762" checksum="037949C9D8561BD0" modified="2023-09-13" version="1">MKPTFATAAAMEAPYDQHYPAPYSSLRESSPEREYSQHPRQHSSPSSSSSVSYPSSSSSSSSSSYTHRHISDEQQYHQQRQQQSNDYRQYQQESHSHHHSRQSSELSQSKSHASYVSSTHRAYEQYAQSYSNPTYNVKHTEGYEGRVRNTNRDHNDHLVTDSSARDQQHHHDQFRRDPTYGYLKQQPSTASFSPMEDDLPAYKYQLPPIHVPEQPFYRSDLPGRHMRYFSKVTSQDRENSDGYFSSARHVAPSNTTGNFGHGPPINQTLERFESARQRQLEKQRQQAQQEQGHRLPSLYTALPEQRPNTNSSMVSQQHESRQSHPQHQGLQPRARSPLRSPTELPSGSNGHHYQGYSQQQSNKIKPLQPRSIAPAPISGTGPLSPVHQKSMTSPTTPLSQKQALSTYASERQSVVKAEPRETTLPHQHYRPQRPLEHHQHQHQSSESQSEGKRKWVRDHSPVRMGSGPKACVDPAEQQQLSEATSQELHLLSRRPTLSGHGQVQLSKGSSQNQPRTRMQRYQMTTIRCWHGAIAQKSYGIEKRYLCPPPMVHVSAGVNAKQIQSEQSHVTMSILHEKLSNGRHDPAGSENLMEQDCSLDDNLKCSFRNLHVTGTGSDSSKRFKLGLQVFLGKNSTTPTALMDSNPIPIISKPSKKTAKAGNASCFILNGMSVSLLNRINAQTVRTKYMAVDNNAVCAKIGSWSSFTIKMVKPPPAPPVKIAPTGNMGIFRAANHSTKFVPIRMKGDSNQPLTTITHASENLNGPSQMPPMQQYQNHQASYHSQQQRHVPRQQQSSHGHAGLQPTQQVQPEPTYVFSNSEPVLYGSEIILINDLTGVTTDRLIIRKVENGKVIRNGSGPVSQMQKIVLQHPDRVHPEDGRPYYLSASSIGSPKIEGKIPLQAAMDRSPLLEYRTSSKKASILDLTETIEEDEDEYYGDETGNLGKRRMPKSQENVAVDDFVCWTIAGIAKFEYTYFAPIPASIDTDVNPKKVPKVLSRPRYNSQSNMMVMKVKNVFEKLSPAEEEARLRSVYLDDPYERRQTLSEFVYRRCEDVRQPIQDEEGPVQLWLAQHGAIRMRRRLLKDVLPDEAEVDDEQDQDDNEDSEPETVMTNEQTNRKPGQVQTEDKLPKIPTKPSAAAYGRFQQQQQQKQQQPEAKTKRVKVLSRAMGLEAELPHGSEVRTTHDANGNSYIELDILMVERASGIAYPTGYKVAYSHNKESSEWTVEVIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N289</accession>
    <name>A0A9P6N289_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Calcineurin-like phosphoesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_002964</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000176">
        <property type="protein sequence ID" value="KAG0021140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N289"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46546">
        <property type="entry name" value="SHEWANELLA-LIKE PROTEIN PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46546:SF4">
        <property type="entry name" value="SHEWANELLA-LIKE PROTEIN PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040352586" description="Calcineurin-like phosphoesterase domain-containing protein" evidence="2">
        <location>
            <begin position="22"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="3">
        <location>
            <begin position="52"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0021140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="228" mass="25407" checksum="80334E660F4FCEA9" modified="2023-09-13" version="1">MLRPILFLALLCILLIYFRQSTPPPTTSPSSSSASNKLKHPKTSSNPIKSNRVVAIGDLHSDLPQALAVLQLAKLVDEDGNWSGGQDTLVQTGDIVDRGPDTIALYNLFDKLRKQASDAGGKVVNVYGNHEVMNLGGDLRYVTEEDYASFGGRQKRKEAWDVRTGWLGQMIYSNFNITYIHNGHTVFSHGDMEPQWARLGVDMLNHLSREAIWKSNYRYAPIFQGSGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2C6</accession>
    <name>A0A9P6N2C6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">KIN3</name>
        <name evidence="14" type="ORF">BGZ80_011539</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010000094">
        <property type="protein sequence ID" value="KAG0022658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N2C6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08217">
        <property type="entry name" value="STKc_Nek2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000097">
        <property type="entry name" value="Probable serine/threonine-protein kinase nek1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051131">
        <property type="entry name" value="NEK_Ser/Thr_kinase_NIMA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44899">
        <property type="entry name" value="CAMK FAMILY PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44899:SF10">
        <property type="entry name" value="NIMA-RELATED KINASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 14" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="4"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="374"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="444"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="596"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="781"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="300"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="374"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="409"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="444"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="473"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="532"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="596"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="636"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="658"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="703"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="739"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="783"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="813"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0022658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="858" mass="93714" checksum="54EA14594EAC01F2" modified="2023-09-13" version="1">MEEYEALESIGSGSFGLIRKVRRKSDGKILARKEIDYRKMSTKEKEQLVAEVNILKDLKHPNIVEFLERVIDRENSFIYILMEYCEGGDLASVIRRHREKSVLIPEEFVWSIMTQLTMALHECHCGMSRNEETNQPMPRAAILHRDLKPDNVFLDANKNVKLGDFGLSRSLSNPQKAFAQTYVGTPFYMSPELISESIYDIKSDIWSLGCVVFEMCALEPPFLADTQAQLSAKIKLGRIQTLPSQYSYELNVVIRSMLQLSPRKRPTTTELLANPKIKVCKKHLENERRAEELGIRERLVSEWTEKYREREAALASYERKLRAEEQRLREMDTVLMSKEEAIRTREATLIEQEKRLAWERQQLDDKRRELLLEQEKRQSGERKSMSSKLSNEPMAIDNGYLQDGTTEKPSISSATPMSAPTASHPSLASASATLDQYLSTRGSETASVADQAQHTWSVPRRKTGLSAGGRHSLQPSNTYRGPTPSNTNGTSIQHSTPSSEVLETGETHSNSRPTSTPASIQRPSVLGLFGTSNDSQSSSSKSTQGQLHLGLNGKESRLSGKLVPLGGFTTPSSSTVDLQRLRGKSKSASTLIASMSSTSLSSATPTPLLPPSSKPFLVPELPRSAMSTATSGRGFPAGSSNPNSTTSTTAATSNDTPMSFTTETPHQSLQPTVAPNGNGYNRPAPSSNGASSRPLGFHPHPTSLSSSSSAISNYTSRRSLASGVPSVGQPRFNFSPALTSTTTGGTSTTAFTNSANSPSGNNGGGVSLTATSAAATNINSGSHDVSTTLSKPQSTIPFGDERYNRSGTPLRIARQEEGEDSRMEWDNDIPSPFIRKTHMRPSSSSPGGPPFSRNPMGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2R9</accession>
    <name>A0A9P6N2R9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Flavin-containing monooxygenase 1</fullName>
            <ecNumber evidence="14">1.14.13.148</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">Dimethylaniline monooxygenase [N-oxide-forming] 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Dimethylaniline oxidase 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="16">Trimethylamine monooxygenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="24" type="primary">FMO5</name>
        <name evidence="24" type="ORF">BGZ80_002436</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="24" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="24">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="18">Broad spectrum monooxygenase that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including xenobiotics. Catalyzes the S-oxygenation of hypotaurine to produce taurine, an organic osmolyte involved in cell volume regulation as well as a variety of cytoprotective and developmental processes. In vitro, catalyzes the N-oxygenation of trimethylamine (TMA) to produce trimethylamine N-oxide (TMAO) and could therefore participate to the detoxification of this compound that is generated by the action of gut microbiota from dietary precursors such as choline, choline containing compounds, betaine or L-carnitine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="22">
            <text>N,N-dimethylaniline + NADPH + O2 + H(+) = N,N-dimethylaniline N-oxide + NADP(+) + H2O</text>
            <dbReference type="Rhea" id="RHEA:24468"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16269"/>
            <dbReference type="ChEBI" id="CHEBI:17735"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.14.13.8"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="22">
            <dbReference type="Rhea" id="RHEA:24469"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>hypotaurine + NADH + O2 + H(+) = taurine + NAD(+) + H2O</text>
            <dbReference type="Rhea" id="RHEA:74111"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57853"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:507393"/>
            <dbReference type="EC" id="1.14.13.8"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="19">
            <dbReference type="Rhea" id="RHEA:74112"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>hypotaurine + NADPH + O2 + H(+) = taurine + NADP(+) + H2O</text>
            <dbReference type="Rhea" id="RHEA:69819"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57853"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:507393"/>
            <dbReference type="EC" id="1.14.13.8"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="20">
            <dbReference type="Rhea" id="RHEA:69820"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>trimethylamine + NADPH + O2 = trimethylamine N-oxide + NADP(+) + H2O</text>
            <dbReference type="Rhea" id="RHEA:31979"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:15724"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58389"/>
            <dbReference type="EC" id="1.14.13.148"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="21">
            <dbReference type="Rhea" id="RHEA:31980"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FMO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="24">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.13.148" evidence="14"/>
    <dbReference type="EMBL" id="JAAAID010000160">
        <property type="protein sequence ID" value="KAG0021418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N2R9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004499">
        <property type="term" value="F:N,N-dimethylaniline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034899">
        <property type="term" value="F:trimethylamine monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000159">
        <property type="entry name" value="Dimethylaniline monooxygenase [N-oxide-forming]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000960">
        <property type="entry name" value="Flavin_mOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050346">
        <property type="entry name" value="FMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23023">
        <property type="entry name" value="DIMETHYLANILINE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000332">
        <property type="entry name" value="FMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00370">
        <property type="entry name" value="FMOXYGENASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="12 23" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="8" id="KW-0521">NADP</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 23" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 23" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="267"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00029725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00034528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00034536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00034554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00034561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00045957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00047338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00048041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00048088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00049443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="KAG0021418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="579" mass="66589" checksum="5B6848657F4919F7" modified="2023-09-13" version="1">MVDNAQQSDNKPKKRVAVIGAGCVGLTAIKECLDESDRIDVVCFEQEPHTGGQWRYVEVTKERPNPYSSIYKSTIINTSKAMMTFSDYAIPGSWPTYLHNKKVVRYFDMYVHHFRLKEHIRFGTKVVEIRELHDEQNRWMVRFHPVVSWTSAQSPASVTIQEEIFDHVMMCTGHHSVPRYPSFPGMKPDEPDAFTGRQIHSHFYRDAGEFKEKNVVIVGLGNSAVDVAVELSMNQSQVYLSRRNPIWVAPRWLLGKPLDQYTTRFTFWLPLIVFKFISAFLLHLTLPKLHPLMKPNCMMFENHTTINSILHERISTGTIIPQVNIKRIGPGKRVEFEDGTVIDDIDAIIWCTGYHVNYPILDPTIIADGREGLENNRVWLWKYMLPPRHPNLAFIGLFQAVGALMPIAELQCRFLIQTWAGRSSSSSSIPDATRMDKDIQEVQQKIRKQYYDAPRHTIQVDYAPYGDWLAKQIGCFPSFWRLVRHFGVVRGIDLWMETTFGPPIPMHYRLVGPHAWEGDRKKKDDGQSRDGTGEAARQVIWGYKGCKGYTDSKYLRDDGLLLPKDGYQNGVREGMLVEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2S1</accession>
    <name>A0A9P6N2S1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">40S ribosomal protein S23</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RPS23_2</name>
        <name evidence="6" type="ORF">BGZ80_010457</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000073">
        <property type="protein sequence ID" value="KAG0023077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N2S1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03367">
        <property type="entry name" value="Ribosomal_S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000007">
        <property type="entry name" value="40S ribosomal protein S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006032">
        <property type="entry name" value="Ribosomal_uS12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005680">
        <property type="entry name" value="Ribosomal_uS12_euk/arc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003254">
        <property type="entry name" value="PRK04211.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00982">
        <property type="entry name" value="uS12_E_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11652">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S12 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00164">
        <property type="entry name" value="Ribosom_S12_S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002133">
        <property type="entry name" value="Ribosomal_S12/S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00055">
        <property type="entry name" value="RIBOSOMAL_S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0023077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="148" mass="16517" checksum="C2757D8AE935AF9C" modified="2023-09-13" version="1">MYMERKGKPRGLQAARKLRTTRRDNRWADKHYKRQALGTAFRFSPFGGSSHAKGIVLEKIGVEAKQPNSAIRKCVRVQLIKNGKKITAFVPNDGCLNFVDENDEVLIAGFGRSGHAVGDLPGVRFKVVKVSGVSLLALWKEKKEKPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N306</accession>
    <name>A0A9P6N306_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Importin-13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">PHB1_2</name>
        <name evidence="10" type="ORF">BGZ80_010572</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the importin beta family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the prohibitin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000075">
        <property type="protein sequence ID" value="KAG0023032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2016913at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000423">
        <property type="term" value="P:mitophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03401">
        <property type="entry name" value="SPFH_prohibitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.479.30:FF:000001">
        <property type="entry name" value="Prohibitin 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="entry name" value="Band 7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013598">
        <property type="entry name" value="Exportin-1/Importin-b-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051345">
        <property type="entry name" value="Importin_beta-like_NTR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040709">
        <property type="entry name" value="Importin_rep_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040520">
        <property type="entry name" value="Importin_rep_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000163">
        <property type="entry name" value="Prohibitin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057942">
        <property type="entry name" value="TPR_TNPO3_IPO13_3rd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12363:SF33">
        <property type="entry name" value="IMPORTIN-13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12363">
        <property type="entry name" value="TRANSPORTIN 3 AND IMPORTIN 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18773">
        <property type="entry name" value="Importin_rep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18806">
        <property type="entry name" value="Importin_rep_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24140">
        <property type="entry name" value="TPR_TNPO3_IPO13_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08389">
        <property type="entry name" value="Xpo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00679">
        <property type="entry name" value="PROHIBITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="Band 7/SPFH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Band 7" evidence="9">
        <location>
            <begin position="25"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0023032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1302" mass="145244" checksum="5E49F83AE67EFFB8" modified="2023-09-13" version="1">MSAILNTLTKVAIPIGAAVSFLQYSMYDVQGGYRAVIFDRLEGVKPNPVGEGTHFLVPWLQRAIQFDVRTKPRNISTTTGSKDMQMVTLTLRVLHRPDIKNLSQIYQGLGLDYDERVLPSIGNEVLKSIVAQFDAGELITQRELVSSKIREDLAKRAREFHIELEDVSITTMTFGRDFTNAVEQKQIAQQEAERAKFIVEKAEQEKNASIIRAEGEAHAAEIISASLEKAGPGLIELRRIEASKDIAGTLANAKNVTYLPNQKGNNMLLNVPVIQQFYTSQDPAYQKSAQDYLHNLQKETFAWELAPHLLSSQLSVYAIRAIPSYWSDFIPSFCQDLRARVNQSVDGVVMSQQAMELTLLEFFTIIAEEIGRAEIEPPRRSQLVNEVTNGVPLIMSCIQEILVGSNPASKQKALICLKSWVQYGIAFDVIQPILGLALNSLLDDETFDSAAEVWSEIMSSNAAARYQNTICEGLMPCFASEWAKAKHLESIHAESEDVGKSLCQLLSAFGDNFSDWIAARFLRPDIVIYLEMMMGFAGFPGYYAEDEEISDLTLNFWYVLQESLSELQPDDSEDGIGRESLDEDRHVILSSISSASNIVGLNKQSLQAIREASIQVYVKLTEVLRRKLEYPMQKEWMTWTRDIRQEFTGHRQEIADTLINSYHVLHDQILTLLIDTCVMQLDEIQNASLSGTNVTDNPQLEIGLVRLEATLYCLKALSEVVPHNENVQMPRFFSEQIFGRLPKTYVCRASETTLSLIGSYAEWFKLHPQFLLPALNFVIPALEIPQLAPSAAKALKSICDTCRESLVEAIDAFMTVFANVERAIDPAIKGSVVYSIATVIQTLPIERSIGPLVGLLGDIFTRSNECLETRKQRLASGNSGVTATHIQTASGETELEPLSAMMLLQLDFLSSCCKGLQSPLEDEIRTAEERIHLYQRTVEDRARVLSAGGMAVELARSMEQVIQEVVMVWPHEQQIIERVCHIIKTMMTASQLSPLYLPFTTLVRVIENGFQQHAFSCWLDAAAKVVSVYYLETTGGTLASKLGSGLVPNSYNGGAGPDSYTVSSSSTVVDIDSDLPSSANTVARGRTAMELENETVFTHLLSTLISRTLEGMQSMSDMEEHPDVVHSFFAVLSQFVRHAPLAFYSIPPEQTESLMNFSVAGLALQERLALKATLLFLIEFVNQSYDYPVLKQRVDGLMARIGPQMMRGILLGIGGHVPRSMVPQLNDSLYPFVGKYPQECRTWIQALLAEPEFPSKYADQASKEKFIKGILQTRSPKRFKDEVHQFSNKCRQLDGSVFGSAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3A5</accession>
    <name>A0A9P6N3A5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_000218</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000104">
        <property type="protein sequence ID" value="KAG0022446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3A5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0022446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="171" mass="19630" checksum="14E861E0E0E6E938" modified="2023-09-13" version="1" fragment="single">SATASGNLPVAWACKNLKTLELRLAFRQGFTLGLFVDHFMMYCPRITRLHLVMFELNTGQTVGSPDEEGYCKIEPDVKLLVGLVHLEEITLSVRHIRGDLDITGMEFMRLHNSSSRDETVEHDGLRIVWPQLVAFNARYSFPKELDCSEFERGLEAIRPGVEFRIRRPFFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3I5</accession>
    <name>A0A9P6N3I5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glucosidase II subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BGZ80_000484</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Glycan metabolism; N-glycan metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the glycosyl hydrolase 31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000110">
        <property type="protein sequence ID" value="KAG0022343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3I5"/>
    <dbReference type="OrthoDB" id="3237269at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017177">
        <property type="term" value="C:glucosidase II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090599">
        <property type="term" value="F:alpha-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006491">
        <property type="term" value="P:N-glycan processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06603">
        <property type="entry name" value="GH31_GANC_GANAB_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14752">
        <property type="entry name" value="GH31_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000046">
        <property type="entry name" value="Glucosidase alpha, neutral C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000039">
        <property type="entry name" value="Glucosidase, alpha neutral C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1180:FF:000023">
        <property type="entry name" value="neutral alpha-glucosidase AB isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1760">
        <property type="entry name" value="glycosyl hydrolase (family 31)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033403">
        <property type="entry name" value="DUF5110"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048395">
        <property type="entry name" value="Glyco_hydro_31_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025887">
        <property type="entry name" value="Glyco_hydro_31_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000322">
        <property type="entry name" value="Glyco_hydro_31_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762">
        <property type="entry name" value="ALPHA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762:SF54">
        <property type="entry name" value="BCDNA.GH04962"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17137">
        <property type="entry name" value="DUF5110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13802">
        <property type="entry name" value="Gal_mutarotas_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01055">
        <property type="entry name" value="Glyco_hydro_31_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21365">
        <property type="entry name" value="Glyco_hydro_31_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040442255" description="Glucosidase II subunit alpha" evidence="12">
        <location>
            <begin position="32"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 31 N-terminal" evidence="14">
        <location>
            <begin position="101"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 31 TIM barrel" evidence="13">
        <location>
            <begin position="417"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 31 C-terminal" evidence="16">
        <location>
            <begin position="753"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5110" evidence="15">
        <location>
            <begin position="859"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="204"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="204"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00042895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF13802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF17137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF21365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0022343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="982" mass="110504" checksum="B3882DCCA87B339A" modified="2023-09-13" version="1">MDSISSRPSKSKKIILRSVIALGLALGCVSAVKREDFKTCAQSGFCTRNRAYADLAKETPNWTSPYQLTTSSLKLQNGVLTGDLINTQEDKHPSPRPGLSFELHLLDNDAVRVRINERDPVSPRYDGVQDTVLIKPYGLAKDSAYTRLDKDAAGALTIQYGAQDQNKIKVSSAPFKIEFFVNDVPTVVLNDEGLLRFERLRKKEEESKKEEGKEEEGKEESKLVDQDAAGDEVDIKVEKSPLELKLEENLWEERFKDHTDSKPRGPESIGLDITFSGINHVYGVPEHATSLSLKATKGAGAPYSEPYRLYNLDVFEYEIDNPMALYGSIPFMLGHSKNSTAAVFWMNAAETWVDVEKNAEDKDSGLLSWIKSKKAVSTPATKTHWISEAGVLDLFVFLGPTHRDIFRQYSSLVGTTALPQSFSIAYHQCRWNYNSQQDVAEVDAGFDEHDIPYDVLWLDIEHTDGKRYFTWDNAKFPNPTDMQQSLSAKGRKMVTIIDPHIKKDDNYHVSKEGAELDVYIKNKDGNTAFDGWCWPGSSQWIDFYNPKARDWWASQFSYDRYIGSTKSLFTWNDMNEPSVFNGPEITIPKDVIHYGNVEHRNVHNLYGTMFHSATAQGLTQRNETNQRPFVLSRAFFAGTQRFGAIWTGDNMASWEHLEIASPMLLTIGLSGLPFSGADVGGFFGNPDAELLTRWYQAGIYYPFFRAHAHIDSKRREPWLFGEPYTSQIREAVRTRYTFLPFWYTLFHEASVDGTPIIRPMFTEFPEDEAVFATDDQYMVGNALLVKPVSKAGVTRSTVYFAGDEKWFDIKDYSVEQGPGAKEIASPADKIPVYQRAGTIVPKRERPRRSSKAMENDPFTLVIALDSQGEATGRIYLDDGETFNYEQGDYILREFRASNGVLSSHNLKTGSVGKTSEFVQRIGALRIERLVILGSKTKLTKVTVGNGNVAEVECSKAPIGGSYVCTVKEPKVAIGEDFELSWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3Q8</accession>
    <name>A0A9P6N3Q8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">P24 complex component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">EMP24_2</name>
        <name evidence="13" type="ORF">BGZ80_011345</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Endomembrane system</location>
            <topology evidence="7">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 8">Membrane</location>
            <topology evidence="1 8">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the EMP24/GP25L family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000090">
        <property type="protein sequence ID" value="KAG0022739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3Q8"/>
    <dbReference type="OrthoDB" id="62956at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015720">
        <property type="entry name" value="Emp24-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009038">
        <property type="entry name" value="GOLD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036598">
        <property type="entry name" value="GOLD_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22811">
        <property type="entry name" value="TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01105">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01190">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101576">
        <property type="entry name" value="Supernatant protein factor (SPF), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50866">
        <property type="entry name" value="GOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0732">Signal</keyword>
    <keyword evidence="3 8 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040342288" evidence="11">
        <location>
            <begin position="22"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="167"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="GOLD" evidence="12">
        <location>
            <begin position="31"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="118"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0022739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="199" mass="22844" checksum="7C4FE0910981274D" modified="2023-09-13" version="1">MLRKLALFTVAVLVTIQSVAAYNVVVPAQERKCFFEHLEKGDNLHISFQVGEGGNLDIDFWITDPNQVFVEDATKAPAATYNYEAKMSGKHEYCFSNAFSTVTEKTVGFNSLVLKPYKEDTTRKADPLENEIRELAAAIQEVRNEQEYTLARERTHRNTAESTNSRVVWWSLFQSGILFVICVFQITYLKRFFEVKRVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N769</accession>
    <name>A0A9P6N769_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11 13">Cytochrome c oxidase subunit 6, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12 13">Cytochrome c oxidase polypeptide VI</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">COX6</name>
        <name evidence="14" type="ORF">BGZ80_001322</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 13">Energy metabolism; oxidative phosphorylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Mitochondrion inner membrane</location>
            <topology evidence="1 13">Peripheral membrane protein</topology>
            <orientation evidence="1 13">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the cytochrome c oxidase subunit 5A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000013">
        <property type="protein sequence ID" value="KAG0024565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N769"/>
    <dbReference type="OrthoDB" id="5778907at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045277">
        <property type="term" value="C:respiratory chain complex IV"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006123">
        <property type="term" value="P:mitochondrial electron transport, cytochrome c to oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00923">
        <property type="entry name" value="Cyt_c_Oxidase_Va"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.40:FF:000001">
        <property type="entry name" value="Cytochrome c oxidase subunit VI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.40">
        <property type="entry name" value="Cytochrome c oxidase, subunit Va/VI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003204">
        <property type="entry name" value="Cyt_c_oxidase_su5A/6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036545">
        <property type="entry name" value="Cyt_c_oxidase_su5A/6_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14200">
        <property type="entry name" value="CYTOCHROME C OXIDASE POLYPEPTIDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14200:SF11">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT 5A, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02284">
        <property type="entry name" value="COX5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48479">
        <property type="entry name" value="Cytochrome c oxidase subunit E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 13" id="KW-0349">Heme</keyword>
    <keyword evidence="8 13" id="KW-0408">Iron</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 13" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 13" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 13" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00070174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00082700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU368103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0024565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="140" mass="15630" checksum="9802EC3617570FF5" modified="2023-09-13" version="1">MNRFAAISRPLAATARVQVARSAIASRSAVQIRNYSSEHGEETFEHFTERFVKFFDNVDDVFELQRGLNNAFGYDLVPAPSVIAAALKASRRVNDYATAVRVFEGLKVKTGSETVYKQYLDEIAPLKNELGIQTKEELGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SQQ7</accession>
    <name>A0A9P6SQQ7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Subtilisin-like serine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">SUB7_2</name>
        <name evidence="8" type="ORF">BGZ80_008862</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004962">
        <property type="protein sequence ID" value="KAF9991831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SQQ7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.80">
        <property type="entry name" value="Peptidase S8 propeptide/proteinase inhibitor I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010259">
        <property type="entry name" value="S8pro/Inhibitor_I9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037045">
        <property type="entry name" value="S8pro/Inhibitor_I9_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF11">
        <property type="entry name" value="CEREVISIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05922">
        <property type="entry name" value="Inhibitor_I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54897">
        <property type="entry name" value="Protease propeptides/inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 8" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Inhibitor I9" evidence="7">
        <location>
            <begin position="8"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="6">
        <location>
            <begin position="114"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9991831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="195" mass="20595" checksum="F5682945EC6A5CDD" modified="2023-09-13" version="1" fragment="single">DGKPIPDSYIVVLKDGHSAKTFKPKFDDVAKRQNGRGVKPKIHREYKAIPGFHASLNKAALKEIQALPEIAYIEQDAVVKINAQESNPPSWGLTRVSEVDLDLSQPYVYNDDAGKGITAYVVDTGVYAEHSDFGGRATLAANFVDGSANTDENGHGTHVSGTIGGSTYGVAKKVKIVGVKVLDAQGSGSTSGVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SRK0</accession>
    <name>A0A9P6SRK0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Condensation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008041</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004243">
        <property type="protein sequence ID" value="KAF9993764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SRK0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043041">
        <property type="term" value="P:amino acid activation for nonribosomal peptide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19544">
        <property type="entry name" value="E-C_NRPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensation_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF1">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Condensation" evidence="1">
        <location>
            <begin position="22"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9993764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="361" mass="40540" checksum="FE028E415DDDD684" modified="2023-09-13" version="1" fragment="single">MATKGDPYLVIFCAAFDSRELLDRYLGSVQKVVNRHDILRTAIMWEQLSTPAQVVLRQAPLSITELQLDPSDGPMRVQLSNLFDPRERRIDLAQAPLMRFAIAQESDGRWMAVQLMHHIIDDHTSLKQMMDEIQVIFDGHHDNLPEPQQFRNLIAQVRSGPSAAEHERYFRKMLYEIDTPALPYGLSDVSDYGVDIIEHQHTLPQDLNNSLRRHAKRMGVSVASLCHLAWGLVIARTSGQQRVVFGTVLFGRMQAGSGSDRAMGPFINTLPLRVDIKDMGVEECVRRTQADMAGLLEHEHASLALAQRCSNVPAGTPLFSSLLNYRHQSESSSEASDIAGVVYLEAHERTNYPFTLSVEDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SSC3</accession>
    <name>A0A9P6SSC3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_007148</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003603">
        <property type="protein sequence ID" value="KAF9996891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SSC3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9996891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="99" mass="10818" checksum="E52CB702083CEAB6" modified="2023-09-13" version="1" fragment="single">MSGIKAAAIIFNELLSSSIIKKSSLEELRTQLQNNKLSAGSVALQIIEKLIHAFPADEAELDVINNETTKSKLRALADSLCDAIRITNDEKVKPAIQEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SST0</accession>
    <name>A0A9P6SST0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_007118</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003593">
        <property type="protein sequence ID" value="KAF9996946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SST0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="93"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9996946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="227" mass="25737" checksum="EA645CE295C1984B" modified="2023-09-13" version="1" fragment="single">MARRCCYPFLLPIRIILAITTLYCFVAVAIGKKISQDYRTSRSFDLEPGLATEAYFNDPAHFGINITVLISIVFTLYRPDSTYWWLSSPVRRIIFALALASLAQTYGIMLLIRILNVQGRCSNLFFVNTQSRCMVQYSVSGCEILWGVLIIIEAIVTIQQQKDIKWQEQTAERELRTAVIYRPDLSLEAGQGPHDTNNNNRGEFELTSVASQTNERGVGDEEEESLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ST76</accession>
    <name>A0A9P6ST76_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006505</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003209">
        <property type="protein sequence ID" value="KAF9999795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ST76"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9999795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="147" mass="17420" checksum="FC2C6F99BFE38BC0" modified="2023-09-13" version="1" fragment="single">YADAKAPDRPTSAGLEEYMNLNSSTPSLKRDNDPPISRGRRRFGEKLQHIPDTSRSQAVFLKDYRKSLEIQLTVLREEILILDNNLDELVLADERLPWHKPAFDACSARRLVLKEQEAMWDLELRRVRQESLIQKYFQHFENMREFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SV52</accession>
    <name>A0A9P6SV52_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FCH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005263</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002600">
        <property type="protein sequence ID" value="KAG0006515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SV52"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030139">
        <property type="term" value="C:endocytic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032185">
        <property type="term" value="P:septin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001060">
        <property type="entry name" value="FCH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23065">
        <property type="entry name" value="PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23065:SF54">
        <property type="entry name" value="SUPPRESSOR OF YEAST PROFILIN DELETION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00611">
        <property type="entry name" value="FCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00055">
        <property type="entry name" value="FCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FCH" evidence="1">
        <location>
            <begin position="5"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0006515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="262" mass="29738" checksum="46B605A1162C49F0" modified="2023-09-13" version="1" fragment="single">MGYSETFLTERPQDGLDAVQTRLRKAKAIHEQFANYFKERAHIEDMYAKSITKAFQKHFITDTQALGTFAAPWEKLNAETVELATLHGQFSLRISNEIEKMLRDYIKTTEWQTLLAETSCHHIAREFDEKQAKVTKYTKAIEKVSGKKVLITEQKLSEYTQQLESTRTAWKIEGPALLQKYQSLDQNRLENLKQGVSSFEALQTEIALQIVEMSSRTSSSVAEFEPVMDMELFASEASVNLHSIEPHDGASIVSQPSIANGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SVS3</accession>
    <name>A0A9P6SVS3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">W2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_004897</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002450">
        <property type="protein sequence ID" value="KAG0007251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SVS3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052145">
        <property type="entry name" value="Mediator/Homeobox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003307">
        <property type="entry name" value="W2_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24330">
        <property type="entry name" value="HOMEOBOX PROTEIN BARH-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24330:SF19">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02020">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00515">
        <property type="entry name" value="eIF5C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51363">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="W2" evidence="3">
        <location>
            <begin position="660"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="241"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="514"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="846"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="976"/>
            <end position="1055"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="358"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="8"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="29"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="58"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
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            <begin position="241"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="286"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="537"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="557"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="588"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="606"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="846"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="986"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1039"/>
            <end position="1055"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0007251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1055" mass="116633" checksum="0AB02588CB882C64" modified="2023-09-13" version="1">MKSKTPVMMLSQQHQQQQLMPQTSQSMLKSSSYSHVASLHMPSQKNSSFSRTVSPHPQRQQQQQQQQQQQQHLRSPHFRKSSGNVGQKHQYYQQQQYDYHYNYDRNYREPDHPHNEGYMNHHNNRFYCNNHNNNTRRNHNARHADQPRTLALNPAAAASAALAREEASASATVAAEVVPPSSITLAASSTSTVNITPVVSVPTIALTAAAVSGGTSSDAHNSDPEPALGDVEKYLQMQQQHALLQPNNRSNAKENGPRKRSQLGSGDLVGLRRGVPSAPISHTLQESDNMSSNSSMRESPSDCDPFFGTEEEGEGEGSFPVSSDSNNDDTDYSSSVLSSSALDDPLALDRQSRRKRSMQRLIAKNKTLKSSLAQAKADLATERQNRAMIDQIYLKIRKELNMKLDVEEIKVANLTAKLEAMMEEMKVLQEEKESLLTSSKSALSAAGSSPASSSVAATASNLSSSGSAYRIGYDNSNYSLTSGLAGGLMLHHSNFLQGHDEEDEFFTPSNFVAVKEPSTSSSQSPPPPPPPSVTVSLNLPTVQNCDVETSPSPSFSEQKDDEKLEHDKEDEKKVTFLAAPLAIPPRTRSPSPLATAHTANSAQESVDAEGKEEEEEEEEEDDDDDDDDDSDDDAPCTMMEILIKKQQSHSAEDEAQDPPADANETFDSMAHKFLYQALHAKFTAARTILQLDDLLLKYDASSEDLVLVLAQECMKWWEDERIKVGGPLTGGWGTGSVLMPETGDRVSAKVAVETRFKSIYIPLLMHYVASHQEQRVLLDKLEATAKTNDHWMKNHVGQLMTLYKFDVLDADAILEWWQLLKEPQGVSGHVNGLRSMSSKFVAWLQDAEDDSDSNDDDDDDSEDDDDDEEEEEEEEDAHNNNQGEDDGQCGIVGLDLLSSPRDVLHSLDADLAKAQAEKEELMVIGSDDDDAGLDYYYDDDDDDRVSTTSSLERIEECERKRRISFCTNNVIITQNNTCPSSSKKGSAATAIPTTTTSITTSSSSLKDAGEKKDTKSQSYLAVNEGEEDEDHSDNNDNNDNNDEEEEEEEEEEDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SW13</accession>
    <name>A0A9P6SW13_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Amidohydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_004218</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002178">
        <property type="protein sequence ID" value="KAG0007789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SW13"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016805">
        <property type="term" value="F:dipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052030">
        <property type="entry name" value="Peptidase_M20/M20A_hydrolases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30575">
        <property type="entry name" value="PEPTIDASE M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30575:SF0">
        <property type="entry name" value="XAA-ARG DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0007789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="120" mass="12781" checksum="AF6AAEE0933A9B00" modified="2023-09-13" version="1" fragment="single">MQMNPAKDLLAAIDKADADLRHLSLQIHDNPELGYQEHFAHKTLTDFLANEGFHVTRHACDIETAFIAEYVNQGPPPAAGAVVSPMRSVGFCSEYDALPSIGHGCGHNLIAISGVAAAMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWB0</accession>
    <name>A0A9P6SWB0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003975</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002087">
        <property type="protein sequence ID" value="KAG0007997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12254">
        <property type="entry name" value="RRM_hnRNPH_ESRPs_RBM12_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="222"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="514"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="592"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="691"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="864"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1215"/>
            <end position="1275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1312"/>
            <end position="1348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="517"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="881"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1222"/>
            <end position="1236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1237"/>
            <end position="1265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1329"/>
            <end position="1338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0007997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1444" mass="156233" checksum="5F641C57CA1F6AA6" modified="2023-09-13" version="1">MSTFASDASPANATRNIRFAWNDNPNHDAHDSLERNGPSRDLCIPTTSDRSFPSSLGRLQPSSSLFEENEIDMAKLFPNDTAMNKQSTRSFASGVSEMFGRRASLSQLSVFGGIWDQPDPVSLLKHSNSPEVDSFNDVFVFPVATADTSKKTNECVDLVSSLYDNPETDQKGGASGTEQDQNIPITASMSLSAAQDKLNYLASEDSHSQQVPVHLQRQFPNTQQHYQPPPRSLSSHRNSRIHPNPIQPPAVSHAKKASIDELISNNQQLGQEPIQHGGFIPGFDIWSNRGDGQLLGPNTGVRHDIPSQRRKSESILHDLTDFSCVTFNSIYQSNATSDANPSFSVVSASSTRSASPLDANSTCQQSASELFGGGSSLNMCLGSLSSELHLHPQSSLDQDVNSGGQFDSLQTGLHPVNHHGNSSNSHEMCGLCSVQRATVSMGGCGHRVCDVCHRHEKHRSMRLFQSEIPPCPFCAHGVVSTPYTATASDKHSSAQAGVDAIKQSPLPQMNQLSYANQQQQQRYIPQKQPPQNSAQEEIYDRYPHNSQYHYMFPGYNANGASGTTGGLFNHNSQNSHYKLPQGLPIQATAVNSSNQRHSLHFQSQEHTSQSSGLNHHASNFQPANSVSLGATQQEYLNLSAMGRPGMISPPTGMWHEGGVASASSNYGAQDLQYSQQHCPSQAQLTQIQQRRGSQHHIFHSPNSGTGGHHQAHSYYGGVNNNNNNGVGVNMSLSFTILPDLPPAVPPTSPTTKAIQWAVVRVTNIPWDISLQDMHSFFSGFPFPPEHLLSQNVHILMDRATGKTFNSAFIELALTPHQAGMVASARNLKVLKGRLVTVELSSQDELLRAVFPKWIGQFLHGDPMIPGVRQKKNRGNPRSAEEQNNSPSSGQSTLGARGSNPKQQSEVSSTISAIESTTFVTREEINALLVVCRNYKLHFSRKCAERPFENILSIIAKYPWHQPHRILPLHRDHIFELLKLSIESLRTHLNKEYNTIHPTLMTRMVRSAILTPAFTERQKAMVLHVAGCTCPEDIIGWMSPPAPAEAETNDDKINIETKNTPSEDITLEQVPEGVVEEAQKSTLLLNPEDGCHIDGQIESLGISDETKGNVRLINAIVAQQSAKTSGPPTPSPGDVEINVSNLMESSPSISVANTEPANKPENNISSGAPQLNIGMATTTSTVSVSGVTTNPGVSNVPLAPSYAAAVTKRSANLISNGSQALGTPTSSSASDPTPTASKNCTMSSQSTPNETWKQQMSRNMGQQQHQNHSDRPFSFSNFQEFTAPNALLATGAIKSAESALVDTGNCIDDQRLRNGSVPRLGQQPLVQTKSTVSSSATSAREMAPTNTSPRLLSPVIPSVPIHITPASVASDSIVLAVLEEKTKSESILDAIKTITQSTPRLPKPGSSSQMGSFISGTSLSSVAATVSTMGEHANRQQRCEGGETL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWB7</accession>
    <name>A0A9P6SWB7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_004478</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002281">
        <property type="protein sequence ID" value="KAG0007592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWB7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="11"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0007592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="101" mass="10834" checksum="53B2CE9C3EAEF96F" modified="2023-09-13" version="1" fragment="single">MSESVDTPIPTVIIVGAGLGGLILGAILETANISYHILERASELRSLGSAIAMTGNIFPLFEQLGIYEEVKSISLPNISLDLYDTKFNALGSVYAREHNLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWP5</accession>
    <name>A0A9P6SWP5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_003838</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002038">
        <property type="protein sequence ID" value="KAG0008108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWP5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050675">
        <property type="entry name" value="OAF3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31069">
        <property type="entry name" value="OLEATE-ACTIVATED TRANSCRIPTION FACTOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31069:SF12">
        <property type="entry name" value="TRANSCRIPTION FACTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="6">
        <location>
            <begin position="42"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="95"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="335"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="406"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="104"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="413"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="433"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0008108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="574" mass="63124" checksum="66551BFE0086A4BE" modified="2023-09-13" version="1">MATSTLQLLPTTNDIEKLDPSTISNIPGSVAYDLKRLKVYSSCLRCRAKKVKCDRKEPCSRCEKHSVECSYRELASVQLDIRQFQRHLNNPKIRKDGAGILTDTATPVIPTASTTTTTSASPPPSSSEISATASSLARGGSSKNDHTSLPKPSPHNNYECPNPIACGSLAFESNPTISAAGHVRSTADDMEGVRVYKVHRRRYSLKTSKVDHAEDSSRIDNMNVDMTNISEHVDRVRLSDHVADRSMSPNVEEEEDSDNVPIWCAQAVGKHKQTAHEQDMAETFGLAAYLKAKEMEISKDPSRAGETIDFEMELERALTRRMPSSFSRPDRLYSRARKHGQPGHSSATPYARPSHCQLSPYAGKDGHTTSKSHHAQPPPTAQCCCQIAAQQGRALDSCPYSNVSHAGYEKHSTQSLSPSISSPRTTNRDSCDPPRIAYSPSYSPRYSHREVASASPPYSAPHIKTNNWQTTSAPYLSILPPLPSPSTSSGYSSSSRMDVVSPTTELPPIRLSRSSELSALQVGRDGDEPMQIGCKYNEPNVDAWDMIEKPISRKIPLTTKRGRSIKMEMGWILS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWR2</accession>
    <name>A0A9P6SWR2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein phosphatase 1 regulatory subunit 21 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_003043</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001783">
        <property type="protein sequence ID" value="KAG0008801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWR2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005769">
        <property type="term" value="C:early endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.330">
        <property type="entry name" value="Nucleotidyltransferases domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040024">
        <property type="entry name" value="PPP1R21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049372">
        <property type="entry name" value="PPP1R21_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21448:SF0">
        <property type="entry name" value="PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21448">
        <property type="entry name" value="SMOOTH MUSCLE MYOSIN HEAVY CHAIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21636">
        <property type="entry name" value="PPP1R21_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein phosphatase 1 regulatory subunit 21 C-terminal" evidence="3">
        <location>
            <begin position="737"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="368"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="569"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="52"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="141"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="277"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="790"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="368"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="394"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="412"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="422"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="444"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="610"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="627"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="653"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="843"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF21636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0008801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="843" mass="93353" checksum="394A04DC82B0F3AB" modified="2023-09-13" version="1" fragment="single">SLQDLDLLTFHNQRLTKRIENLQNQASTKSGGSWLVGGGTVKKELEKSQSSLEAATIDLQTKIEENEKLHQQLYEINALYPRHVTELQGKIQALEKQNQDLQLDVERAGVANEDTITLIRKEKEATEKELGMIRDVLAGQLQDEQRSNQSLRDNVERLEKEVERLSKAEMELESLQSEHTKLQGELETLKWISSELSQLQQSYSSLERDKMQIEKAHGQLSQQYGALRQAEDNVKRALAQEQENSRAMREMSQQLHRDLEAVRGEAINRERGHIDRIGQLESELEKVRREQGKLQAQYEELKIAEQAAKEGESRTKADLAKDLANMKSSLESAEGKVKELEALKETLEKELADVKVTLEETRASLATEKERKQTVVARAESEHQVEEGEAKTEPEDDHVTEEESVEKEKAPLSKKAKKKKAAAAAAAAAAAAAATAAVVAAEEGGSHEGDDDKDDKEGKGSQDTKRKEEEAAEAAKAKADAEAQEQKQKEEEQARKAVEDSLKAEIESLRQQIKESEQSSESNQEELRVARAALENLKDEKMSLSSSLEMHVELTLQLQQEVDALMADLAKQQKRHGENGAASSKREGDDDESLVRTRQKSPQGAKATKSGDQTPQRASTPVPTAGEEDHAKSASTAKDESTQVDRVEASDKAVQSESVEQVDESTQADLVKEDAAVGASVAPSDVEDSKDGPSGATEASKDVTTSTSAASAGGRSIDNRPSRGSMIIDDSAATAATGTTTMTTTNQSNREYLIKKHYETKIQNITEQLQLSDGRYARLHREFELLKELLMETVNTKEGISKECDELKNRNAVLQEELAAAKEDNRAQVETMTNFMKSLDQRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWT5</accession>
    <name>A0A9P6SWT5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Copper homeostasis protein cutC homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_002918</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CutC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001747">
        <property type="protein sequence ID" value="KAG0008913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWT5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.380">
        <property type="entry name" value="Copper homeostasis (CutC) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005627">
        <property type="entry name" value="CutC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036822">
        <property type="entry name" value="CutC-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12598">
        <property type="entry name" value="COPPER HOMEOSTASIS PROTEIN CUTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12598:SF0">
        <property type="entry name" value="COPPER HOMEOSTASIS PROTEIN CUTC HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03932">
        <property type="entry name" value="CutC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110395">
        <property type="entry name" value="CutC-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0008913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="215" mass="23699" checksum="CC33134413E0973F" modified="2023-09-13" version="1">MIRPRGGDFCYDDDEFEAMLYDIKVISLFQAIGIVLSAIQDIDTLPVLHQLCHSLKVEGVVFGVLLPDGSMDKTRVKKLVDAAQPMQVTFHRAFDMVKDPFQALEDIIEIGGIQRILTSGCERSAYEGLDMLVELSKRANGRIIIMPGAGITDRNVNKIVSAMNAKEVHVGAGGTMESKMEFRNPYCSMGYAISAPEYSLKVTSESKLGGMIQKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWU6</accession>
    <name>A0A9P6SWU6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Protein-ER retention protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ERD1</name>
        <name evidence="7" type="ORF">BGZ80_002856</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001727">
        <property type="protein sequence ID" value="KAG0008975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWU6"/>
    <dbReference type="OrthoDB" id="2159384at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004342">
        <property type="entry name" value="EXS_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10783:SF46">
        <property type="entry name" value="PROTEIN ERD1 HOMOLOG 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10783">
        <property type="entry name" value="XENOTROPIC AND POLYTROPIC RETROVIRUS RECEPTOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03124">
        <property type="entry name" value="EXS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="43"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="EXS" evidence="6">
        <location>
            <begin position="42"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0008975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="153" mass="17204" checksum="308912274B381342" modified="2023-09-13" version="1">MVLINMWMYKWVVNGSDSKDQRNSPTEDVRGGMGLTGNPRVGIMVPILGYLTILVMIFIPFNVLFKKERFRFLRSMKKALFSGFKSEVSFADVILADILTSFARVFGDLTVALCLMFLDRDGTSADACYGSILVPIMTRYKALWWTAKPGGLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXH8</accession>
    <name>A0A9P6SXH8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="15">E1 ubiquitin-activating protein uba2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">UBA2</name>
        <name evidence="15" type="ORF">BGZ80_001814</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein sumoylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ubiquitin-activating E1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001422">
        <property type="protein sequence ID" value="KAG0010069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXH8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031510">
        <property type="term" value="C:SUMO activating enzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019948">
        <property type="term" value="F:SUMO activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016925">
        <property type="term" value="P:protein sumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000618">
        <property type="entry name" value="SUMO-activating enzyme subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.80:FF:000002">
        <property type="entry name" value="SUMO-activating enzyme subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.520:FF:000011">
        <property type="entry name" value="Ubiquitin-activating enzyme E1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.520">
        <property type="entry name" value="Ubiquitin activating enzymes (Uba3). Chain: B, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.80">
        <property type="entry name" value="Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042449">
        <property type="entry name" value="Ub-E1_IAD_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023318">
        <property type="entry name" value="Ub_act_enz_dom_a_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019572">
        <property type="entry name" value="UBA_E1_SCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033127">
        <property type="entry name" value="UBQ-activ_enz_E1_Cys_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953:SF5">
        <property type="entry name" value="SUMO-ACTIVATING ENZYME SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10585">
        <property type="entry name" value="UBA_E1_SCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00865">
        <property type="entry name" value="UBIQUITIN_ACTIVAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="385"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="domain" description="THIF-type NAD/FAD binding fold" evidence="13">
        <location>
            <begin position="10"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-activating enzyme SCCH" evidence="14">
        <location>
            <begin position="319"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="11">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF10585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0010069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="417" mass="46314" checksum="ACF30990BAAFEA2A" modified="2023-09-13" version="1" fragment="single">MPRETHLETTIGKSLVSAVADAKVLMVGAGGIGCELLKNLVMSGFKNIEVIDLDTIDLSNLNRQFLFQKQHIKKSKAHIAKASALGFNPNVNIVSRHQNIKEQEFSVDWFKGFDLVMNALDNLDARRHVNKMCLAANVPLIESGTAGYLGQVTVIQKDKTECFDCQPKETPKTFPVCTIRSTPSTPIHCIVWAKSYLFGLLFGNAEDDDDEVLSKESSDDETAKELAALAAESQALKEILASASDEGFAERVFDKVFHGDIQRLRSMEDMWKTRKAPTPLKYSEIINQTDDLPTAMDVTAQESITLKDQRVWTLRETAEVFSDSLEKLTTRLKDMRASDPEAIVQFDKDDAETLDFVTATANIRARIFGIEEKSRFQVKAMAGNIIPAIATTNAIIAGMMVMLAFKIINKRVADCKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SY85</accession>
    <name>A0A9P6SY85_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_001578</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001362">
        <property type="protein sequence ID" value="KAG0010336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SY85"/>
    <dbReference type="OrthoDB" id="10387014at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0010336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="74" mass="7764" checksum="3B6B065B073E1DFA" modified="2023-09-13" version="1" fragment="single">GHSSLDQALPGVVLEIVVSTVGHVRIGIPMAGINLSYTVIPTEAPPETKVFKAPQVIPAPPDTPIMSILLRLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYB1</accession>
    <name>A0A9P6SYB1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">WD repeat-containing protein 24</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">WDR24</name>
        <name evidence="8" type="ORF">BGZ80_000683</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001148">
        <property type="protein sequence ID" value="KAG0011442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYB1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061700">
        <property type="term" value="C:GATOR2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016239">
        <property type="term" value="P:positive regulation of macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904263">
        <property type="term" value="P:positive regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037590">
        <property type="entry name" value="WDR24"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46200">
        <property type="entry name" value="GATOR COMPLEX PROTEIN WDR24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46200:SF1">
        <property type="entry name" value="GATOR COMPLEX PROTEIN WDR24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 6" id="KW-0853">WD repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="265"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="352"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="616"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="16"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="55"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="616"/>
            <end position="632"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0011442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="690" mass="74093" checksum="6CC14588BFF3C530" modified="2023-09-13" version="1">MNRDMLKLRKDPTIPPSAATVTTSTTNAFPVSPRLGGTGPETRGGSRHRTSPKGPGTGQGIALGPGLGLGTGATSVVAPSSASATSATSMGSNSSPSATTATNVSTSGSTLIGGTNMVMGSSNAGFGVGIAPGSLLGFANGHATRALSGTGGASGAPRQSRIPASSPQAFKFDTGGTLWALSASPDFSMVAVVGRDVLKILNVTDNAAEEAINLKAVAGARNFAGSMDVKWGPTTGRDAKIATIGTNGVIFIWDIGTQNKIDRTIKEHTRAVSRICFSPQDPNLLLSASSDSTIRLWDLRLRDRPGLLMDGKDIVREVQFSPVSVNDIVAGYDGGNIQRWDLRNLSSNVKRFLAHSGFVTSLDYHPSGRFLASGGKDKTIKIWDMEDEKRREMHNIPTIQYTSKVQWRPNKPYQLAASFKDEPTVQIFDVRRPFVPLHILTHHDKDATSILWKDTDVLWSVSKDKTFASTHIKGQTISADLLPSSSGAMSCYGQLAFTVLSKGNFDSFEKDLIPRTGRPNVRSVALDGSVEATVYRTRQTGGVFDCELFNHEAFIYCAQNYSTDANNVREACEHNSNIAWQANRYRDSQTWTAIKLFYSDMAESAAIVSQVDAASTETPNAANKQTDGQAQDGNDIDSDASETQQSRPAVPSLFAIKVSDAPVKRTWSHEETIRSLLEYYAEQGEVQIVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYC1</accession>
    <name>A0A9P6SYC1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_000885</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001199">
        <property type="protein sequence ID" value="KAG0011157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYC1"/>
    <dbReference type="OrthoDB" id="10009287at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004345">
        <property type="entry name" value="TB2_DP1_HVA22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12300">
        <property type="entry name" value="HVA22-LIKE PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12300:SF161">
        <property type="entry name" value="RECEPTOR EXPRESSION-ENHANCING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03134">
        <property type="entry name" value="TB2_DP1_HVA22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="151"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="315"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="490"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="151"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="162"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="179"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="339"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="365"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="409"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="501"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="519"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="546"/>
            <end position="561"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0011157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="561" mass="64473" checksum="67C7B678D6BA265B" modified="2023-09-13" version="1">MASFPRAKVDSSTQTDPPLPFTAFLDRTLDRVEATVPLNLSSITFYIRRHHLSRIEQIEALLSRNFFFKFILYRIGLKPQHVFSFLFLLALYGCRQLYRRSVYLTTNLCAVAYPAYCSIRTINSEPIKPPRGLGLEPTEYSPVYGLRRSSSFYSNTGSTHSNRQRARKRHSRMSNSVLEDSMQSSNSYSSSQEDYESRRSEASSWGRPSEYNYSEDNFTTTSGSISMTVEEKMKQRMRRKWAQFSQTRKDKATRQWLAYWSIYGTVQVVDTWSSFLLDWIPGYNLGKLLFLWWAQRRGATLVFDYFQPLIQSKNKDGREVARKPSNRSLNSEMSQQRGGSSGGADGSGSGRPRSMQMLPSTLAHQQLQQQQQYQQHQFEQQFYTKGSSSRRDTAAFRDLNQNRHRRDDYYDDGEEEDDDEEYHSHNQQRQYILQQQLLQQHQKQQDQPLDLRRELMASSPHDSGSFAEAPLFESAESVWSAPPGSSSVLVVDSEGMGGARSHSNNATPTPMSVQEQYNLRQQLHQSTQKQQTLTPDANSYAVASTMHWNPATSSATSTEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYI6</accession>
    <name>A0A9P6SYI6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_000557</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001116">
        <property type="protein sequence ID" value="KAG0011612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYI6"/>
    <dbReference type="OrthoDB" id="2419989at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="289"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="326"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="436"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="567"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="619"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="766"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="911"/>
            <end position="957"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1046"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1116"/>
            <end position="1159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="447"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="574"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="624"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="917"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1055"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1116"/>
            <end position="1139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1150"/>
            <end position="1159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0011612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1182" mass="129435" checksum="FBBFFE600FCF63EB" modified="2023-09-13" version="1">MSLSTIVGESPTKVTSLSSSSHLVADLDTFLAKAPTVTSPTAPIPQMSAPVDKSDSSHTFTYQVSVTKTARHKKGNVVRSRSIKRVPSQKRSEHGQSVSRDEVARDNIPSMEMLLEILATVVSRAPDQWAPIHLIDFFKQSRGHTIQELLKKLPTTASQYMMFLTLKISSTWIETFIILRAKGMPASNTSTSDSLYGSSSIMEQPSVPVNLKALRNEARCVVSRKLAAYIFLRPPETDVGAPFLQGVELKDPSGMASSSQRSQVTTVIEADAITALEVLIRAYENLSRRRKAGRGATESRKTSVYPTRKSSLASLKRTLTLTPADIPSLSLPPWRKSAPGDPKTMKSNPQGGQPSVARTFLRRQEHHARETPITDSESSMTISEVAPFEVATVNTIQRSSNDSKLSISACIPHPVSAMLAVPVIEATYNPEQLVVPSHPAGSDSETDATPNTFPWSTETPHYPTEECLSFGSQFNSDLLVRAAAAAYNYRSSYRQCLSNEQSQQRPRRSRSKARTCGAIIAQGSTGGMGEFGPISSHHSLPISAPETKSLGMSSTLCFGKAELSEEENFDKTEATTGLSDNISTMNLQDEDEPDEPLKPPPLQKVDVVLAKGADLPPAGALDSSAATPSIDNTTTVTSPKPVMPLKIKSAESKNVKRHRPPPFVLETASLANSLRSPQSPPLTHTMVMPFSVKMTTNPDTQVGATAGSTSTLKRSIVGQMPHASTEVQQQENLTQDIRNIESPSPKKGRQLWTKSSLLLKPRSSSKTDLSVGLTTGNAVSNPNNSSSPIGTPKSLKITNQSELFLNSITNETSDSVMDVTMSSKTRRHMQSRSQDFTRAQRSIDGVVVSNGKSIRHVRSGASLRSSTKAISMPLPEVSSPVLRSPANSAALKASPSVDEISSKTTPSWPSFLWRNPFQPSSPSQTGNESSELLKQRNSPEEPSSPSPPSSVYPDLRRKKSIHEKLFGKWSKKMPSFSSPLSSPQLSSGTLEYAPCNRYSASSFSACGSSATSPTLQHDHGHTREPHWYRLTNETGDSNYDRMNASLSKVRKKGKEIKAISPREKRDSKTGDVSRQDEIWERILDIAMDNSSNTLKPENEEPYTRSKLEALWIDDENDFDGDYEEEEDNDDCDESDDDRFDFETGGYEITNSRRSERESKSEAYICRVMEQWQVWSIAHAAII</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYN8</accession>
    <name>A0A9P6SYN8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_000148</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATP11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001024">
        <property type="protein sequence ID" value="KAG0012183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYN8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033615">
        <property type="term" value="P:mitochondrial proton-transporting ATP synthase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010591">
        <property type="entry name" value="ATP11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014807">
        <property type="entry name" value="Coa1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13126:SF0">
        <property type="entry name" value="ATP SYNTHASE MITOCHONDRIAL F1 COMPLEX ASSEMBLY FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13126">
        <property type="entry name" value="CHAPERONE ATP11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06644">
        <property type="entry name" value="ATP11"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08695">
        <property type="entry name" value="Coa1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="281"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="287"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0012183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="483" mass="53773" checksum="7C5D638445B0E974" modified="2023-09-13" version="1">MSASRCSRLNVSILGLRASPASNQFRVNLLPRSTLLSKSYSSSPSSTTTSSSHASSKTTSAFAQNPAFKSTSSLNQSQHSPNFKAQTTQLPDIKSRTPFFIFFGILGVAFWAGSLAVAANHQRQGTSIVRGTLFNVKFDKKAQELLGENIDFTNKNWPWISGTVAHLKGRVDIEYQVRGDKAEGRVHFVAVRPVKQWITTDFTLTMPDGTSPRLGRSVYPSTQQQSSKLATVTNARIFFRSKHIDYTQKYAEKLKRKAEEEGVASLDELKAKLLPATQTAFKKAQPKDSTTATTTTTTATAKTADQKDKDRANAASEKPYDSGSPSLDKIMKLNLVKDLSADDIGKIWIQKHMEQEDTISAVVPAETYKKMLSRAKEYPMFAFHQVIFTSLLEYQTHLENARPFLTLTHYPELIDSKGIVLMKGVISTEPRLLTADQAQVLTFGLQQYYVSDHKEKLQLLHDFHKKPAQFSHEKLVALTEISG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZ29</accession>
    <name>A0A9P6SZ29_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DDT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_011545</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000940">
        <property type="protein sequence ID" value="KAG0012742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018501">
        <property type="entry name" value="DDT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028941">
        <property type="entry name" value="WHIM2_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35711:SF1">
        <property type="entry name" value="ECTODERMAL, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35711">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15613">
        <property type="entry name" value="WSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50827">
        <property type="entry name" value="DDT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="1422"/>
            <end position="1445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="1452"/>
            <end position="1476"/>
        </location>
    </feature>
    <feature type="domain" description="DDT" evidence="6">
        <location>
            <begin position="383"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="156"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="469"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="716"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1168"/>
            <end position="1389"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="540"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="617"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="17"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="31"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="159"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="208"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="469"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="721"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1189"/>
            <end position="1220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1221"/>
            <end position="1239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1282"/>
            <end position="1298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1314"/>
            <end position="1323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1336"/>
            <end position="1349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1375"/>
            <end position="1385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0012742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1477" mass="164355" checksum="2456D007D1659332" modified="2023-09-13" version="1">MTVPPDSLNSDAKQGKLRPLTSLPMPMLPTEQQLKSTPHQQPAPYRPRGAPQNSLLSSWLTHANSNANNSINDSNNSFNGVNSNTSNIRGSAFGSDQGYHSIGAPSRHWTEPHPQREFHHAIDVDRAHLNYSVGSVGTERDQRQIQNAIDARHCDLSHTSASPTSATTIASPPLQSPDHTVPGAIEKRKRGRKPKSKTEPVEGEDSDPGSKEKKPKVPKEPKPPKEKKIKDPKPTKELKPKKSKKDLNDEASGAGSGIKTERSYFAIRPVAPTVYTVTFVIVVAVLKENRNDSSASSTASLKSSFKQSCLSFDVLDPSKAGDYLNSMAAASREDDKRFGGFVRELPKLTGRAPYEDLLSGMLLRSSKLPNLTKLNLHHPDLDMDMLADVKMVHEFLNTFGTPLGLTKDSGEWITFDLLLSMIRNPRIDSRLLELNCKMVMAAYDEEQSPKINQYNFPYFLAVGPEARSTLEERKDEKKNRYSGSSRKKPAPMNRLGAIEYSVYTIADRIEALVKALHDITSSDRFHRFMRDEVEENITALKRQKRKRAEVRKELETQTHDLEREMKAIEREAAELETKRQAILTSERESGLAEEESGATRITAASRLQRLAQSKDARSKANELLNQQKMLANDLKAKESAWESKKEELEEISLDDTVVQKDHNVPLTQLRGGHVVNADEKLRVICLGSDRWGRKYWFWKEFGGVIVEDRAQVDPKATGDTQKLDDSNKDKKSEGMVATTDNRSETIDESLNDVTRRLKTMAQPELAGDKFQVTRDRMSISNLLSDDGPSHESQLAAPQMPRLEPAKPVPEKDLLDYGPIQTWSLISTSKELASVSRALNAKGIRERVLKASLMAMRKEIEASFCRIKAWAGNEYAVKNEHTVSVMGTVGQPLSEEDLMLLKKKRGRKSKQELADIAATQIELASAGDDSQIMDLDYVRSSDRSPTSGIAHPQDVEMEYDGSDHEQEYTHEGNDMILEKDEVTDGFMATVRDSDSGPLPSEFLESIICAAEEKLKDISRAICNGDANAIPVAIKGVLPQEGQDDCQLLRTVRVLEHCLYLMDGPILDVDDQDNHDDPKVQDTLGNSTINPKPHIGIDTDVAMDDEAVKPLMIAPGKLSITIPVSINPKLLSWLKTCRIDVILKDVKTFGALHAWLDECIDAVETVVYDTDEDDDNEEGLNGIGKKKNEYYEAEEDENEEDDDEGEDDDENDHEDEEGEDASDDKNHGGGHEGDEGGDRDKGRRGRQRKTCKETQLRTTTVRGRALRARSNMPVSYKYDLRNDDNEDNDDEEEDNDDAEEEEHKQEENEEEGIAFRLRRLAKHAHRDRDERTASRVDTTGGTTSGGVTQSGAAPQPTTQAQPGGEGAVTEAPLSGGNNAAARPVARAPKNRRYRVKKAHNLARDLTLMLLLVVTLNTFGLGSGVAVLVLTWIFTGFAIIWIASAIVFEHFILDLVFGFIEMALLLAILITAFVMGWAVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZ90</accession>
    <name>A0A9P6SZ90_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Translation elongation factor EF-1 alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">TEF1_2</name>
        <name evidence="4" type="ORF">BGZ80_011263</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000887">
        <property type="protein sequence ID" value="KAG0013133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZ90"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001857">
        <property type="entry name" value="Elongation factor 1-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050100">
        <property type="entry name" value="TRAFAC_GTPase_members"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23115">
        <property type="entry name" value="TRANSLATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="3">
        <location>
            <begin position="5"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0013133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="144" mass="15772" checksum="080FBC45D4B982E8" modified="2023-09-13" version="1" fragment="single">MGKEKTHVNVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERERGITIDIALWKFETPKYYVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGTGEFEAGISKDGQTREHALLAFTLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZB9</accession>
    <name>A0A9P6SZB9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">sn-1-specific diacylglycerol lipase</fullName>
            <ecNumber evidence="14">3.1.1.116</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BGZ80_011808</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a 1,2-diacyl-sn-glycerol + H2O = a 2-acylglycerol + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:33275"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17389"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
            <dbReference type="EC" id="3.1.1.116"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:33276"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.116" evidence="14"/>
    <dbReference type="EMBL" id="JAAAID010000999">
        <property type="protein sequence ID" value="KAG0012341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZB9"/>
    <dbReference type="OrthoDB" id="438440at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016298">
        <property type="term" value="F:lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019369">
        <property type="term" value="P:arachidonate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046340">
        <property type="term" value="P:diacylglycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00519">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052214">
        <property type="entry name" value="DAG_Lipase-Related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45792">
        <property type="entry name" value="DIACYLGLYCEROL LIPASE HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45792:SF7">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_6G02710)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Fungal lipase-type" evidence="16">
        <location>
            <begin position="618"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="216"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="440"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="856"/>
            <end position="902"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1003"/>
            <end position="1023"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00024531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00026104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0012341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1081" mass="117203" checksum="6767C3531C19CE2B" modified="2023-09-13" version="1">MLLDKYTSLGVYVIHNTFTLAELFTISGLQLVSNTVTAGIRTAEESVRVVDGLFGSTETSRALAAVVGLVKKEVYDDQDVAITNAGRMAVLASITKAITVFACLQAATHKRTQKTIRAMLVYEGVVVAKPKKLGSESTQLATLGQSAMGNEDDEDSGELLKDLSNALVTDPDDVTEDMTTTQIEKVLSADILQVTTTTTLTTTTTQTFIRPGADLSILGKPLPPIQHERESPPPPPLQRQHSHYAASIEAASSSRGASSTVAITARSRRGSVSSIASVATTLTQYATTSIVANPHGSVKSTTRSVPTASSVFAPSESLVTEGNRQANNNLRLMFSTVTKKFKKSQKVQIGGDEDGTVLMRTQEREIRSSEARSSLDWSEDDTDWIEVTKSSETTSSMEMNTTVSYDVPLENENGANAFGLKNGLSSKKFGKSFFSKMTKQSSFGKKTDHRRSTESMAPQLTITEMDESRSGSDNSLSCKVEDDSQAANPALVDVNLNYDDDKDSRPPPPPKEPKEPNPTNFPKDHLVRNIQRFMRYASASYGHNFMRILGIGTIGDTVYSPYGDHPNHHAFAAHTSTPLDSILLSSFTDPGATGNFQAPKMHSLVHYINLDHGAQCIVLTCRGTLGLSDVLTDLCAHYEELVMPTLKPNGERGERHAGSRYQVHAGMHASAQLLSHKTSTVFKTIKEALEDYPDYGLVLCGHSLGGGVASILSLLWSMKSEEFEAYVEQEDGSSDDNDEDEAVLRSKANGARRRQSRNRILYPEITTPFVTSPASGLPAGRPIHCYAYGPPCVMSLPLSKHCEGLVTTIVHQYDIVPTLSLGLLRDFKNVATTLHEEGQVVEDIVKRLIIGASSNRANAERQAAEAKVPSRTYTSPVNGAGPTPPPSPPQKEHPEAPKRSHSMPIYSEYDRWQLQEAEDQDWSWSLIKTMRADMGSDKLYPPTPVYLLESVATTIVPPMPTTVAAHSSAAAAPSSVPLSKSFSASSAISAAGAAAASLANGIRPGSPFGRRSTPAPDVKPAPSYIPQVPKPAYKVSMRRFDHVEDRFGELQFARTMFTDHNPANYEACVERLCQAVFAPDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZJ2</accession>
    <name>A0A9P6SZJ2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ysc84 actin-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_011102</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000851">
        <property type="protein sequence ID" value="KAG0013403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZJ2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051666">
        <property type="term" value="P:actin cortical patch localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051017">
        <property type="term" value="P:actin filament bundle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051702">
        <property type="entry name" value="SH3_domain_YSC84-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007461">
        <property type="entry name" value="Ysc84_actin-binding"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15629:SF2">
        <property type="entry name" value="SH3 DOMAIN-CONTAINING YSC84-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15629">
        <property type="entry name" value="SH3YL1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04366">
        <property type="entry name" value="Ysc84"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ysc84 actin-binding" evidence="1">
        <location>
            <begin position="96"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0013403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="174" mass="17517" checksum="E05BF3FFEBAA4F71" modified="2023-09-13" version="1">MSSLKKSVSKINSPLPKDLAGECKKASKILNAFIDPIAAEGIDNIIPPDILLKAKGLAIFTVVKAGFLFSGRAGSGIVVARLDDGTWSAPSAIGTGGMGFGGQIGAEITDFVIILNNKAAVKSFSTGGNVTLGGNLSVAAGPLGRNAEAAASASMKSVAAIYSYSKTKGLFAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZT1</accession>
    <name>A0A9P6SZT1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_010733</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000780">
        <property type="protein sequence ID" value="KAG0013980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZT1"/>
    <dbReference type="OrthoDB" id="2380458at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040382270" evidence="1">
        <location>
            <begin position="24"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0013980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="280" mass="31325" checksum="CC54B4974832900F" modified="2023-09-13" version="1">MASHSLVTLTCLVLLLLATTINALPAPKAPFNQLPFRFDVSAPKLDTVWRVDSLPRVSWDAAKMPEKSTMDIALLNHERKESVLLRRYVPAHLGSTLVNLRPEITSGTYSLLLTVYKGRTSTAIGRSLIQSLILVDNEAVDPEELLFHADTSNVEKKESVVFKKQNEVTLESELVELTHQPTKGNLVLRAPYTVGWTIPKALENVRNVRVNLLLVNRRGETIRTLVSNIDAKAGFTYVFLPEDTPIEMYRIKVEIVGNGRKFSGYTHRFSTSLPAFSARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T000</accession>
    <name>A0A9P6T000_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_010096</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000668">
        <property type="protein sequence ID" value="KAG0015013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T000"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="322"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="322"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="115"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="178"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="279"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="33"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="120"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="279"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0015013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="383" mass="41093" checksum="3F0465DBA3697F8F" modified="2023-09-13" version="1">MSRVLPPLDINVPPSADGSKKFKRVRPVEGAVATATASTTTTTTTTTSTPGYISMNPTVTPASAKPVVVQMPTATASVASSTPQKPTLAHNSIPYIPSDMAVAAASAFDAPPIVSTPTPASAGNGASTGSTTGTTKKSRKKRKGASGSTGAVATDAAGSIQTPMQGGATLYQEDLSGTNKAQQNNTKKRKKGQNANNQSGTDSKKQLERKNKKIRRKDRQQILVRNLDATPELVGVSTEDDFSTLLVKHVEHSNKMLQRDLEKQSKMMMEEQKKQAKLLATQAAQLSDPQAAQQALEQQQQQQPQQQQQQKKNLQNKNKTPFIPRKDCIYFLRGYCRHGEECTFKHDVEARDAHQAQLSEGGSNVVSTMGASGDLAQVAMYAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T050</accession>
    <name>A0A9P6T050_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_010088</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000667">
        <property type="protein sequence ID" value="KAG0015023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T050"/>
    <dbReference type="OrthoDB" id="2440626at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040481095" evidence="2">
        <location>
            <begin position="19"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="314"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0015023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="469" mass="50452" checksum="8BA6CF361F9EB6BD" modified="2023-09-13" version="1">MVATHSLLLLAILAGSSQQNGLRALAQAYQDSEHYVLPANIYDNLPPGLQTPVAAPTIAAPSPTTLAVTKVSGIVPSVPGPDDTMSLEILTPLLNSIYTPGTGLVVSWTNDEVSFPENWAPEQSILDMITKAPNFSNSSLLTKEDMTNLAKAKLIGLRRAQLLSVLKESSVRLHSLRLLSWPLIPPVTGDDGKASTNSHYISPSILSDPGLPILNFSQIGMLGGAGGQMTWMIPEDWEYEGEFEIRIPSPSGMNGSAAVSAGSAWGGAKSHGFWILRDLATRTSHPQYNIPPMDQQQRVMSGWRGGDSQGQKVLGVFFGIATVMLAFVLIGLGGMIGVYYHKWVAQVASSPESEPLTIDNNLPSYSPSSGLAKNLHQMQGVDPFVIATGDEDAHSPTDLKDLNVSDRAIGGIEAAAMSEKAMAGKDCRERYNPVDRSFVDLPLYEAWESTSTLAASNQDFHEKMHETKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0V9</accession>
    <name>A0A9P6T0V9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_009747</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000610">
        <property type="protein sequence ID" value="KAG0015618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0V9"/>
    <dbReference type="OrthoDB" id="2416556at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0015618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="105" mass="11500" checksum="20D7538594D2684A" modified="2023-09-13" version="1">MRVAITPIVKTLPRVSMARIPVVAFANSHPSAYSSSTWAESAKTKADNLEQAAKNIDQAENSSGLSHHASEAIRLLESHSALKQDKATIHTYHDVDHGEARYVKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0Z3</accession>
    <name>A0A9P6T0Z3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ion transport domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_008858</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000496">
        <property type="protein sequence ID" value="KAG0016857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0Z3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005216">
        <property type="term" value="F:monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098703">
        <property type="term" value="P:calcium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024862">
        <property type="entry name" value="TRPV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10582:SF2">
        <property type="entry name" value="INACTIVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10582">
        <property type="entry name" value="TRANSIENT RECEPTOR POTENTIAL ION CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69322">
        <property type="entry name" value="Tricorn protease domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="809"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="841"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="893"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="962"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="718"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1074"/>
            <end position="1101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1130"/>
            <end position="1178"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1181"/>
            <end position="1219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="729"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1074"/>
            <end position="1086"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1130"/>
            <end position="1145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0016857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1223" mass="137996" checksum="B1228A15A1E9AA48" modified="2023-09-13" version="1">MADNSSNQGGGNVVASPSDEADIKEINEQNETRMVAGQEEEVETPTADILEWRSKMEAMESPNDHIVFGSGRPDQIVSVGPCNPGLSDRPVTIAGYDISGTGGYATTLYFEDDFAHIDVWDLSQNNSNNLPTQPHVVGVPFARTKIELKESQDIEVVISNMGTHVAICSSESDDVSFQLFKTVPSRPADKDFSLPWKLEKSETICDGNCYYPMFFYRKDRSNSNEEDERFFTADRCTFAVYDIQGKWTQIYSTSMQPHLDIGMAGVPLTSIQGGYFAWVTAVGVVSIWNSETGQLVSHIYTGAENQIGNPCISPDGTMIAIPVKNTIQICDVLTGVKLGVFKKGLSNDSIFEVIFGKEYFITLMMNRHSLIVITGTEFIITCLRPFKGEEFIRELEIKVDGKTDIGGARTMKIPLGIDNLSYEGFFIPTTSQLVLITNGFVQVWNLSATATRLCELTLIWKFQEYPKGVKETDYCKREIVSAVACEHGKSIRIDLAAAKWSNEFEGTLNVANQNPDTLTIPITNDDTFKSAKDHRTNKGFLGLIPLYVYGENDCKESVIHFMKQHIRPTVRNPTSCLLALCDKLTPTAITIAKAIMDYCVSRAVRSRNLAFLSPLFGSLREVMKLAPEAALKCLGRIAYIPVIHRSYIVDNCVVAQPPTFRLKFWEPINKPLSEMKDPIMHLDIVSSGLNRSNDKFTRPVFMASFDALWHHTVLESPGKANDTQEANDTQERDDTHETDDTQEGDKLREVQTVQTTTWWKTLYHMIRLKTRLRIHKYVECYDFDFQFFDNPAIAALVAYKWNTIGFTYWLVRFVFQCFFYALVVIVALLQVYDKDHSNQLVGVFIAIIAMAVAFLWLEILQAANSSMRRYTQINESVCKYVTIIQQAVVEIRVFFFILAGGIFAFTIAMQHLFWSCPYGEEGGCKQPTTGFPENFLGALSATYFFMGGITDPVSDEFATNDWGFHLMMAIFFFFTVILMLNVLIALINVAFTKGDDGWRLVWIESRLRYIESAENMSYHIPGFRQTHNWFPKEIYFTATLQEVRDYRKKHTKDKNKDKVDLEVTVDWLHGAVDTDDFENEGVDEDVNGNNGNDGMDGQDSDFEDQIEDLNVANGQASDFEDQIDDIKAADGEESTDKESEAEAKVTDPPNPSTATIEQVEEDKEGNGSTSPRDNSADKFLIRDFNQQIGELKTQVGDLQRQLLAQREQAQSQFDELKNLLLQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T187</accession>
    <name>A0A9P6T187_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Hypercellular protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_009246</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000536">
        <property type="protein sequence ID" value="KAG0016409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058565">
        <property type="entry name" value="Ig_TRAPPC9_Trs120_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058567">
        <property type="entry name" value="Ig_TRAPPC9_Trs120_3rd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058568">
        <property type="entry name" value="Ig_TRAPPC9_Trs120_4th"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058564">
        <property type="entry name" value="TPR_TRAPPC9_Trs120"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013935">
        <property type="entry name" value="Trs120_TRAPPC9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058563">
        <property type="entry name" value="Trs120_TRAPPC9_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21512">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21512:SF5">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26254">
        <property type="entry name" value="Ig_TRAPPC9-Trs120_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26280">
        <property type="entry name" value="Ig_TRAPPC9-Trs120_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26282">
        <property type="entry name" value="Ig_TRAPPC9-Trs120_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26283">
        <property type="entry name" value="Ig_TRAPPC9-Trs120_4th"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26251">
        <property type="entry name" value="TPR_TRAPPC9-Trs120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08626">
        <property type="entry name" value="TRAPPC9-Trs120"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="Trs120/TRAPPC9 N-terminal" evidence="5">
        <location>
            <begin position="4"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="Trs120/TRAPPC9 N-terminal" evidence="5">
        <location>
            <begin position="93"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="246"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="Trs120/TRAPPC9 TPR region" evidence="6">
        <location>
            <begin position="345"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="domain" description="Trs120/TRAPPC9 first Ig-like" evidence="7">
        <location>
            <begin position="655"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="domain" description="Trs120/TRAPPC9 third Ig-like" evidence="8">
        <location>
            <begin position="1140"/>
            <end position="1282"/>
        </location>
    </feature>
    <feature type="domain" description="Trs120/TRAPPC9 fourth Ig-like" evidence="9">
        <location>
            <begin position="1307"/>
            <end position="1430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="220"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF26251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF26254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF26282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF26283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0016409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1431" mass="158711" checksum="DAE4605B17D3DC37" modified="2023-09-13" version="1">MDSVNFTSAARTRVLLVPVGPIKKATFERHVKLLRQHNSVKLEEVWMGPRTDSSFFSQNVPHEGQLYFHFATSYNAEHQYLEEFQMHRRIFGYPSAVANQCFAFDPSEKQPDDLRGGGIIMIPNVGNTSSYLRVLICDMARTILTEFENIAAAIGKRQDIESPSPGISVYSRAQNPMANAPSVPDMTANGIKPLMAPPSAMTSGSANHSRSMSSAGFASMAPGNQYVQPPQPTVVTDPRLRKRTAARAQKLYGDLYLMAGRLTDAVSSFQSVIEVTKSNSDFLWQASAMEGLYCAVVLLAFVQADLTQIQQQQAQQSIMSPTSPTFSETTKVQNTPAIKPLIIDIPEKYQTILTLYNKLPSSSSPAILYVEACMKVTKFIATCFVCGGGILDDRALAAVVNGNMFVNPDGTVIEGQNPMTQVQSGNHSQNNSLASGILRKASTLRSRSGSLTTPSSLGISRTDIMSWVFKTWTGRMDELWIVDQIHYTITIASILGAIQFRRKQSLYLRYAVRMIAPLLHQTRLAAAAAAAQAGGAASKRPKNPDHGVLDCLTQICNIFGVGDNFTSSNNLYMDHGWPELQIDVLYECIRVAEAIPDFKAMMHFTTILLRQLYAYLTREEQAGLYASLPRILAAAKKTNVPDFTEVHYWTKSLIIDIEVCSPSSRKQPFTRTKDTLKSFIPETKLTAKPAEGDPFIYNPFHRKVNNVAKLDLVAEETAYFIVTLTNPHGIDLEVQEIKLSTSGVEFEAIPTSTVIPAQTTVSIKVAGIPKCPGELVIRGCLAQILHCAEQEFFVTNPRNGSVVDTSNKTKAQTLVGSEPFPRFKKRGLESFSLSKSTNDPAAAEPKFATVTVIPTQPLLKISSTSLQHGSVMLFEGEKTTMHLTLENIGSIPVDFVTLTFSDSTSQLAIGNNYGNTNSNGVEVSAEDAYEMELFLKKTNVFSWSREVECHIPVGGTREIKVDVLGKRGCSSGMIQIDYAYLHRENDKEAEESNVFVTRQLFSQVLMTVYKTVESLNFDILYLQSHGGMDIPVTEPNTPVLDGSNDDGNGTFANTEPSVPSIDFSSDGFLAPPKSDTKMVQFQRVAGRRGSRTISKRLSSNFAKVDKRQSVEQLLSKARGDAVLPGEQIEAAISRRVALGTKNEYCLLTLDVRNVWTVPVEVSMLVDDSEDGEGLDINKLIKSTTVIQPGNTQRIILPVRRMVLSTEQLSTPIPTLSNKQFVVARGTALSSEELALERSLFWFREELLKRIVARWSCKDTSGRFGKFDLRTLRLTKPMLNVLKIEDISFLVTLEPTETMAEEKQEANDNGEIVIRRGLEQIGSNRWRCPVDRFAQIRFTVVNRSHMDVKLCLRTQPVQVHGDGTMEYDMGTRMVWHGVLQAPLAKLQPDSTTSHVLPVCFYSRGEFKVLYHAEDVHRRVVYYDHEPLVIEAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1I5</accession>
    <name>A0A9P6T1I5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_007928</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000416">
        <property type="protein sequence ID" value="KAG0017781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1I5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0017781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="251" mass="27961" checksum="F6F555535028DCC0" modified="2023-09-13" version="1">MATAGILAGAAAVSVAFVVGTRKLYKAIIADKDVTLPSLGRLNHSLRESAYPDDFYPDLYSRGYSVGPPVDHNPSLYVTQLTELLEHVGWRKCNLVGYSLPSDLPWVAKIFLLPYSAEILSKDPIKNYFSKKNVESMLSEFKGDVPYCIKQATEIMRLQFASHQGYPRGLMSTLKVFPLTGLDREFSTCQLHSYPVQAIWGTKDTVIPGTSITKLQKLVPRIKVTNVEGATHSIVMTHPTEIIDKLKDFVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1S7</accession>
    <name>A0A9P6T1S7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006589</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000326">
        <property type="protein sequence ID" value="KAG0018894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1S7"/>
    <dbReference type="OrthoDB" id="5552418at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0018894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="194" mass="21524" checksum="67AEDB7CDCD732CB" modified="2023-09-13" version="1">MDNDSLGSPNSNASTISCPNSPTQRSHITEVDEQAASDELAAIQEELQNVLEYVDQGMILKSFDTLCRLTDIIATNCEKLGLASDGGAIDQKAGFWTGLNNCWLFAFWHCGNARSEDQRLQRHHLYHLHDSVKAWADALEKYGLVNYELGLSEQDILEAIEFCLINAAAISPSSKTTKSIEDEENENSEDEDII</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1Y4</accession>
    <name>A0A9P6T1Y4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_006891</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000343">
        <property type="protein sequence ID" value="KAG0018672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1Y4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0018672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="87" mass="10176" checksum="11B90360F3ED930C" modified="2023-09-13" version="1">MMGVARVYGQQYNFYYYVITFDYDLAVEHEILQPLKVIQDFELEMARGSRKKELAVEFGWATQSTIDLRDSLSDNSLSPSCKYSQIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T222</accession>
    <name>A0A9P6T222_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005641</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000278">
        <property type="protein sequence ID" value="KAG0019540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T222"/>
    <dbReference type="OrthoDB" id="2421390at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="22"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0019540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="260" mass="29172" checksum="0F2ED84035DF3CC4" modified="2023-09-13" version="1">MNRKTTVESSSNPTMRREDSNKNSLSAKSSTTNTSNAVSGKSTSDKRSLTQAEKLRAFNLEMAMREGASKDQSRAKRSENREPVPKQAKEVKKELVRPSSIATEMFEINSSSSGYHGAYASAYHYQGFKLTGEQMNFQPTTRRQSLQSTASRQSTYPSLSGQGTQQDADRNMRKSFNQKRNSQSTTNVVPVVNKSTVKMKQVKAAHRQSNTDQKVIGDSYGGCPSGGDFEEKCYEIEELYARRMSIRSNKSVGKRWDEWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2A3</accession>
    <name>A0A9P6T2A3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005450</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000269">
        <property type="protein sequence ID" value="KAG0019653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2A3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="398"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="499"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="843"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="892"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="919"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="444"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="506"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="549"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="580"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="656"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="708"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="765"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="894"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="923"/>
            <end position="951"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0019653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="982" mass="109761" checksum="F49D30AB9B94CCE3" modified="2023-09-13" version="1">MMLILSSQEFDPGKGVNWIAGSEALRVARVISMLKPESTSHIQSHEYLYTLDLPRIHRMLRPIKAKISAIHLAIKSSPSFGYAPINVATTGDVFDEDFPEDSYIVASRNVKQQYGQSRSLRTRHRGPQNYLGYRKNISIDLPSQQIYPNGITATSGSNTQNGSDTLVRRFRSSLIDLFRDVVEKVWWQPFCEDHDLPLNSTPTSILEIGLAPNSFTLAKSCAFAVGRIVAHIQEADSAQMEKYYNIMPDHMRRSGGNTRAESKGGLKDVALGLALHSLYIAVTNPSESNGDEKTQEWVRLLETRMAYGIRQLDFDVVVRSYGTLTNLNALALMLDAVGLYALSMKLMSRMLEDFYTLEKNTRKQLGRYDDVLGDWVERTPKPNKTALIVFDDDRSDSGYIEDSPAPQPENHGDLSYDLPSRSAKAFSLGSLPSEHATRRFPRQDTVTRSSPSVQSNPATEQSSCRRRHTVESSPFILRKKIRYSMTPIRRPVRSSRQRVYYNDFGPELDEDEEEEAEEEEAEEEEGDSDGGTGVDIANIHTLTPSNDMGGEEEGDNGIDLEPRSSALSRLPYLDDDYVQLSGSNSDDSAQEVSDGVVGEDSQDADSGISSEGAPEAIILSGGADDSSCSYENHGPSGGQDSSTGTDSESEQEAKRSRSRRTRAKIRGSRGDDDDYLAPRSARRKRSQDNVYDNQFSAPHRSKYGYNARLSSSKDLATTESEEDSDIIAYQKRQPARPRRPLISTRQSESDDDFQPLRKSKVVIEQTVRPQRQTQRRAVLSHVSNSQALDSSRRTLVRRAPSSTSTFESKKRTSNVIIECLSEDSNDSGVESSDLRRLRGKEASLKSSNSTYSLRSKRSLESSSESDYTEITAKKRIRDNAYYHAEKKIKRTIASEEDTLQDGTDCSDEESDCERNVCAVSESENTEWLEEHSAEDEDNESSDENGDEEDTMDFCKEENAFSVGAPLPLTEPDELAFWICEPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T373</accession>
    <name>A0A9P6T373_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Aldehyde dehydrogenase 8 member A1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ALDH8A1</name>
        <name evidence="7" type="ORF">BGZ80_001805</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000142">
        <property type="protein sequence ID" value="KAG0021739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T373"/>
    <dbReference type="OrthoDB" id="310895at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004030">
        <property type="term" value="F:aldehyde dehydrogenase [NAD(P)+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07093">
        <property type="entry name" value="ALDH_F8_HMSADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000001">
        <property type="entry name" value="Aldehyde dehydrogenase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000026">
        <property type="entry name" value="Aldehyde dehydrogenase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000012">
        <property type="entry name" value="Betaine aldehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43720">
        <property type="entry name" value="2-AMINOMUCONIC SEMIALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43720:SF2">
        <property type="entry name" value="2-AMINOMUCONIC SEMIALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="6">
        <location>
            <begin position="21"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0021739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="483" mass="52828" checksum="24DCEEB0DAAC042E" modified="2023-09-13" version="1">MAQLTIENFINNEHVKPSLGNYFDAFEPARGLPYAKIPDSTKDDVELAYKAAATAFPEWSKTGRPERAKVLYRIADLLESRLDEFARAESRDQGKPVELARTVDIPRAVSNFRFFAGRILHSVEEAGELPGVGFSYTQRMPIGVAGLISPWNLPLYLLTWKIAPCIACGNTAVCKPSEFTSMTAYLLCSVLKDAGLPAGVVNMVFGTGMNAGQAIVEHPRIPLISFTGGTVTGAKIIANSARYFKKLSLELGGKNANIVFEDCDFDLALKTSLRSSFANQGEICLCGSRIFVQRPIYERFLNGLVQGAKALKVGDPTKSDVNLGALVSKEHWEKVVSYIDLGVKEGGKIECGGQKPPSLADEFKNGYFLEPTVISGLTPSCRTMREEIFGPVVTVYPFDTEEEAVALANDSEYGLSCSVWTENGRRARRVAGEIQAGTVWVNTWMARDLRMPFGGMKQSGLGREGGEHSLDFYSELKTICLAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T471</accession>
    <name>A0A9P6T471_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">DNA-directed RNA polymerase II subunit RPB7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">POLR2G</name>
        <name evidence="10" type="ORF">BGZ80_007426</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000038">
        <property type="protein sequence ID" value="KAG0023895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035097">
        <property type="term" value="C:histone methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042800">
        <property type="term" value="F:histone H3K4 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15489">
        <property type="entry name" value="PHD_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45838:SF4">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE TRITHORAX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45838">
        <property type="entry name" value="HISTONE-LYSINE-N-METHYLTRANSFERASE 2 KMT2 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="10" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="9">
        <location>
            <begin position="449"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="9">
        <location>
            <begin position="663"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="78"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="273"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="318"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="369"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="747"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="940"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="100"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="274"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="981"/>
            <end position="1002"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0023895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1809" mass="199391" checksum="FC24DF4B36E67188" modified="2023-09-13" version="1">MNMDRKSSQRLLPPRLTHDRPQSANVHLASLSPVPNNTIPSPLASPITATANSLTALSISQTSAHSAFSGRDLSKITIPRERRKSRPYSISSAESLLVQERGRADRDDDLHQDQSGGGLSDPETSRRNGLGTKPTAKNGKSAEMKSPSLKPASQLRVNLYNLVSTGYLPVDTLVVFREHSATVTAKGTLIPQIKEPNAATLYPWLQSEYETPSAWATAMVKGGRTGKVAVNGWSAIKIPLHQLPEIGKMVEGQGLTEVSLDLLRKRYLADLTEDGSTQTESSSTQTNSLKGSSVLDRKKRKRHVTASVDTIGLRITTQTNTGDQKGRSATMRPRKRTMSDVSGMVGSDLLQDRQLHLEAAGALFSMQDRSLSPTFDTPSRRGAKSQGTRQKAQRHKHRILLESLARHRQEQESVWPHLSPMQSSLRAVKVMSLVPGIIPLDPSSSVSHLEFCVLCGASGQVAGSRRRSSAQSMTSHHWSSVDSTEATFDQDSYEQDAMKRCFDCGECYHIDCIPTDTTNSRLSPSPSEEPWRCPRCNVCSCCQKSIHEAPSSQPKSSVDSKEILVLSCCKCCQFTHLQCQLTHEPTLKGLNRSNAVNEKVEWACFSCRKCVECGYRVQVETQVENSEGRSINNSKSKDQSKVEGRWSNGSALCPACTVLAEKGNICPLCCRVYQDDDYETPMIFCDGCSLWVHVACDKGLQDRDYEELGEDSRQYFCPSCIPTPIPSPAHSSSSSSLISAVNSVEQSPWQGPYSHSRDSSSVTDEDWNHRGRRKKDDILDLIKAAKEISDSESQADSPYNSYSPMFPSNHSRTMSASLESVAEVAAAEALLTIFSGANTPVNSTPYTSYPPSPYEPSFNSMYERRYPVINSPQESPLLTRSMAFTPLPSGQESSTCSTFGCQGEASCQCYRNDGNFSEDYFNSREYPRPTVSYHQIGQEFNVSSENPERPEQLGLTESSRDVIMEETGVGVEQEQMKQGRDANTSMQQPLAKSDPQSSLYQPFSPQYRPLQESMLTEVTPIDESLQKSVDTRECLLCRNRSGSNRGAPCKESQLGRLLPIKWTSNEAGEGLESLSFGWIHSQCALWSSGVTIDSNTGGMSGVGSVVGQCWNTICSACGQPGASIKCKAAASRISDASYACTAVFHYPCLNHHRPSQALHQDPLHQHTNANNAVVMDQKQRTILCSMHYREVSTLNDLRTAAFALQSSVMPANSFAKVPQVRPGISTPGSMKPWSGPIWIKDSLFEDSLSRASIPLTNRIEDHDTKAKSNQEYHLRKGRSSESFRIGGLVIHSIGNFDPPRPVHCETGLGNDIDLDHKYNPGLQKEKKNLQSEVLALPLGFKCERQLLLEGSIKYSVVAEVVLHRFNGDSQSDAEMVDAPVSMSGPLDGAQDHENMCPAWKITVNALGSNPNATMRDCVFYSDSINDVIETLFLSSDTECPEDKSRLRQNKLYLQSPSTFFGLDHPVVRRMILSLKGEKEAASRMWLRYREDQKALERQCRKHGCFSNVSSGRTLSKHEHSLEHIESIGAARARSRPRSQLMRKRVVRVGIALSHGGQRIRQSMAVGDLPMPGLMQDFSKYIVTATTPQKEPHPNGVSSKSDITVKQLQKLHAEQPNNVALYWNGRKVTTIATAPHAQPPVHRKDPTNSVCCYGESSKDDVAASDLTDMEVDCIGGNISENTILNDAESSLPIHADMRVYATRAYQQDEMIMEYVGEVIGPAVAIRRQAAYQKQGRGCYMMWCDLHEVVIDATIQGGLARHIRRDDLGLGSVYAKTVVTSPPSSSQSPKVVICAAKNLLAGDELTMKYCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T4V0</accession>
    <name>A0A9P6T4V0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">E3 ubiquitin-protein ligase PEP5</fullName>
            <ecNumber evidence="9">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BGZ80_008105</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the homotypic vacuole fusion and vacuole protein sorting (HOPS) complex. Component of the class C core vacuole/endosome tethering (CORVET) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Endomembrane system</location>
            <topology evidence="8">Peripheral membrane protein</topology>
            <orientation evidence="8">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Vacuole membrane</location>
            <topology evidence="9">Peripheral membrane protein</topology>
            <orientation evidence="9">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the VPS11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="9"/>
    <dbReference type="EMBL" id="JAAAID010000043">
        <property type="protein sequence ID" value="KAG0023778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T4V0"/>
    <dbReference type="OrthoDB" id="26184at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033263">
        <property type="term" value="C:CORVET complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030897">
        <property type="term" value="C:HOPS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007032">
        <property type="term" value="P:endosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048284">
        <property type="term" value="P:organelle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007033">
        <property type="term" value="P:vacuole organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006904">
        <property type="term" value="P:vesicle docking involved in exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16688">
        <property type="entry name" value="RING-H2_Vps11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057308">
        <property type="entry name" value="CHCR_PEP5_VPS11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000547">
        <property type="entry name" value="Clathrin_H-chain/VPS_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057307">
        <property type="entry name" value="PEP5_VPS11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016528">
        <property type="entry name" value="VPS11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024763">
        <property type="entry name" value="VPS11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23323">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23323:SF24">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 11 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23341">
        <property type="entry name" value="PEP5_VPS11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23356">
        <property type="entry name" value="TPR_PEP5_VPS11"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12451">
        <property type="entry name" value="VPS11_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17122">
        <property type="entry name" value="zf-C3H2C3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF007860">
        <property type="entry name" value="VPS11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50236">
        <property type="entry name" value="CHCR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <keyword evidence="9" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="9" id="KW-0926">Vacuole</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="14">
        <location>
            <begin position="53"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="11">
        <location>
            <begin position="398"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="15">
        <location>
            <begin position="950"/>
            <end position="986"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="610"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="658"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="907"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="610"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="666"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="707"/>
            <end position="721"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR007860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0023778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1043" mass="115794" checksum="7477D17E04357E05" modified="2023-09-13" version="1">MALQRQFNFFEKVEVKDPEDPSKPPEIFKSIESNVATSGRGHMVVADRSGLVHIIDKGLQGESFLAYDSGRVTHVKQLRQRNILVTVGEDDNTGQVIKLWDLDKPDRNRPGPTLERSIRVNQAGNAFPVSALAVLENLSQIAVGLANGTVVLISGDLMRERTTAQKIVHQNDEPITGLGFREQQRGALLFIATTAKVILYNTATKTSQTLDDDQGGSLGCSVMNESTQELAIARDEAIFFYGPDGRGPAYALDGPKTFISFYKSYLVLVSPPNIPAAASRSFGISSATVSANDTTKLTVIDTANKFTAYQATFTQGIRSVICEWGSIYIVENGGKVYRLDEMDTSLKLDILFKKNMYLLAINLAHNQKYDNASISEIIKKYGDHLYNKGDYDGAMAQYVRTIGRLEPSYVIRKFLDAQRIYNLTSYLQELHSSGLANADHTTLLLNCYTKLKDVKRLDEFIKTDSDLTFDLETAIQVCRQAGYYEHAVYLAEKFDEHDLYLTVQIDDVKQYDRALAYMRRLGPIEADKNLQKYGKVLLTHLPEQTTQLLIDLCSGTLVRGEAVRPVHGATIPVVNHIGQAPPPASSMRGAGGAASPPVILSGAASPNISSHAALSTKNRSSHQLDPAKYAPPSPRTFMSLFVDLPSYLITFLEKVSENRWSPPSPSQSSQPTASSSGTSLKHTAGSPGKPGSIGGKKAGGIVDFNDKASTSGASRSGTMTEQDMEERKAVWNTLLELYLAGPPKAPSTQGNKSSTMQVAEMNRKMKEKNIMREKCLKLLNDTEIPYDTNHALVLCHMAEFNEGIVFLYERMKMYTDILRLWIERDDTNKVIECLRKYGPLEPSLYPLTLSYFSSSPGRLTSATPELLKVLDHIDQQDLLPPLRVVQALSQTSVATIGMIKNYIGRRIEAERKERLEDQKLIQNYRAESEKKRREIEELKTSARLFQATKCSSCGGSLDLPAVHFLCKHSYHQRCLSDAADRECPKCMVDQRTVADIRRMQEANAEKHELFLSELEDADDGFEVIAKYFGNNTMAFARLVDSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T4Z5</accession>
    <name>A0A9P6T4Z5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_007134</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000036">
        <property type="protein sequence ID" value="KAG0023947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T4Z5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="370"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="2">
        <location>
            <begin position="754"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="206"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="254"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="303"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="849"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="962"/>
            <end position="987"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="33"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="254"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0023947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1122" mass="125671" checksum="D49D26D002D7C0D2" modified="2023-09-13" version="1">MSATSLSRRSGIRAPSGAARGSSKINPNALPRPTQTSIFDNNTEYGSSVEQSTASTASGQQATNEEKEDIRTRLFDDNFTREYRPSYYSASAPSVINIGTNGDSGGAAIAGVIDTLSPRIERQRPNTLHQDSLVAGKDIYEYHDHEFPAPPRTSNHIAIQQQEQRQQQLQRQQQYIAPPQQLPRPFLQNQQLFARWVHGNMNRALSRSKIPPRSDSMESSYDNANRPALNASESYPSNDAEGVQLPVEYLDLVEESEEGEEEEEEGEELLVDYSDDDSQGSGDYNQGNVQKFQLQDTKIYDSNQGTQEDSQAPIGRSRSPALHSDLPVSTGPVKHYTPEIETQETLKRERTRILQRTVVSSYRQINYKDITNIQPLKKGGFGEIHTAEWSHLKVVLKRAIEGRGEGVEQFDQELEILKRVHDYDFIVPFYGVTTDPVSKVKCMVMKHCTNGNLCSFLEKHHATLSWGERYRLSIEITKGLEFLHKSGFHHRDLHSGNILLDDKRTAMICDFGLSRSSSKARTSDLVAAVGVASFLAPERFPTKRPIYSAACDIYSLGVIFWHISSGRIPFAKRLRDPALLSELMDGRREEIVPGTPREYRDMFVKCWDVNPARRLKIDVVIAILQTLMAKPSEPIHQAHQGLMGFMVPSNTVSAALPVPPELDTKMASLERASNTLNRMVFDIKYPAMRDTVNYIERTRAFFREQRMPAEPYSPTNPPKAPIYFCPLVGDIAGLNYYLSQSRPYNPINESSEQTGDTALHLACLFLESPLDTIKVLVELGADINLENLQGYTPVMILVSSNTQYCYEALKYFVMRGARIPAYIRKPITPMNNAQIYALNLVNESRRGYPSGTEDNEYRWPRNGTGAQNQNRSGRRIDRFYAQGRPLIHVVAAMQDDHRILDCLCEAGLDPAISFGGETALVAAAAHLKIKNIEWLLNNDLDISAKAEVARAIKVVRMLHVSVPTSPTEPGRSRGSPNPSKLNPKEFPDDVRDLGKYSWAGVAYRDSERYSKDMVGPVLQLLEQWTGSRRITARKDVATKLKLMHGATVQTDVTNQPGAISPVAVATSVHNNNANMPYIPPPPPSLGRISSSNGPALRQLSLRKNQRHLIDQVLNDKSPAKFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MCT9</accession>
    <name>A0A9P6MCT9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AMP-dependent synthetase/ligase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008556</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004674">
        <property type="protein sequence ID" value="KAF9992428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MCT9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043041">
        <property type="term" value="P:amino acid activation for nonribosomal peptide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF1">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9992428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="213" mass="23378" checksum="5362353BC4B7F0B0" modified="2023-09-13" version="1" fragment="single">MSMLETLRVVVLTGEAMPPTLPKILKTLAPNSTIINGYGPTETTIGATLWTCTPDFCGDIAPIGRPMNNKYIYLLDGQLKPVPLGAVGEMYIGGVGVAREYLNRPELTNERFLPDPFAVEDGARMYKTGDLARYLPDGNLVFLGRNDHQVKIRGFRIELGEIEARLTDHPLVSKAVVLTLGEGADKRLVAYVIASHDEHLANSLRSHLAERLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MD73</accession>
    <name>A0A9P6MD73_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_008323</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004478">
        <property type="protein sequence ID" value="KAF9992976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MD73"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9992976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="151" mass="17165" checksum="F0042E41033655C9" modified="2023-09-13" version="1" fragment="single">MATPPSMESPLLDCVQNIPDVETPLRQLRLERLKGRGGDVYISPRAKASPRATDTFDLTDKVQEFLNSDKKVFLLLGDSGVGKSTFNRALEISLWDNYEKTSGRIPLFIHLPAIEKPERDLIAERLRKVNFTESQILELKLHREFILICDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ME53</accession>
    <name>A0A9P6ME53_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007636</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003947">
        <property type="protein sequence ID" value="KAF9994979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ME53"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9994979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="56" mass="6980" checksum="A805CB1C87870E17" modified="2023-09-13" version="1" fragment="single">DRDHRDRDRDRERDREKSRRDYPDDEDTNRNRYSKRYSDDDGDEPEEQQQQPAAPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MEU8</accession>
    <name>A0A9P6MEU8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007596</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003914">
        <property type="protein sequence ID" value="KAF9995143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MEU8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9995143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="143" mass="16710" checksum="6FA646928A1F2B9B" modified="2023-09-13" version="1" fragment="single">EDSRCKYHVSLILKRWFKEELQDETDLRTVTGPESFQVAFPHRRSIPSTREHPTDTYMGNVHSLFTAESSIPPSSKESRRRKREYAEVIRAARYIASKIRDDRALYRELVNALKKIESSAKRRREGERSSSGKALENIKDSRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MFH8</accession>
    <name>A0A9P6MFH8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BGZ80_006994</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003505">
        <property type="protein sequence ID" value="KAF9997497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MFH8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003400">
        <property type="term" value="P:regulation of COPII vesicle coating"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045260">
        <property type="entry name" value="Sec12-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23284">
        <property type="entry name" value="PROLACTIN REGULATORY ELEMENT BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23284:SF0">
        <property type="entry name" value="PROLACTIN REGULATORY ELEMENT-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <keyword evidence="3" id="KW-0853">WD repeat</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="266"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9997497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="290" mass="31499" checksum="7937878645801A51" modified="2023-09-13" version="1">MAFGINSAINKIEAGENENCRIFQYVGDKIEAVHNRGTLKSKNPDDYQKVTCFNNDGTMLATGGTDGVIALLRYPTLAAVMPAIQFKEHEILDIDFSSDGAHVAAVSAQTLWIISAATGEVLKTIPSPVLDKNKPSQFRKCRFGKGEFTNILYTVNNGEKKRKPFVCLWDTSNWTKIRSLTVGPKPITACALSPDGSLIAFGSEDLGIRICSGKTLQVLMTVPNAHAWPLTSLAFNGDASLLVSGSFDTTCNIISVPKTFPKNNNLAIMILTLLVLLLAVIFQLYQSSQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MFY7</accession>
    <name>A0A9P6MFY7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rhodanese domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_006935</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003468">
        <property type="protein sequence ID" value="KAF9997721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MFY7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="2">
        <location>
            <begin position="291"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="219"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9997721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="392" mass="41377" checksum="57A10058F3022941" modified="2023-09-13" version="1" fragment="single">QNPASSQPTDSRISTLTSTTNDPATLALLVDPSSPPTQPIASVGPNSTSSSNIATATARPTPSFASGFFAAAQDPSTHLASQLPVETPFFTPQAPWTEHSRSDYFSTASISHTAATATSHIISPDGIHPSQANLFASGFSLPAQTPAAIEIPSFAASSPSYFPSSNQSTNASDQEPRGFQLPPPSTLSSTKDRNGSSASIPRSNLALSMPISSLMMSPTNPSSPFSLHSPTSSRISMSSLSGSHHSPPPAALPAELKLQVMNCETVSRLLEQVLGNNNNNSIGDDSGKGGDRNAIMLLDMRPSILHAASSILTAVNVCIPNMLLKRVSCSLQMVADQLTTEEDTENFSRWRQFSNIVLFDATGAAPVVGSPTYFMIQKFRKEGFNATIAYLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MG20</accession>
    <name>A0A9P6MG20_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_007065</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003556">
        <property type="protein sequence ID" value="KAF9997165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MG20"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF309">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14510)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="19"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9997165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="248" mass="26450" checksum="C96EAE849681A0F9" modified="2023-09-13" version="1">MSDLKNSSTYHTPNPSNPKIIIAGAGLGGLTLAILLEKASIDYEILERATTLKPLGSAIALAPNVMPLLEQLGLMGELKGISMECMGGGIHRDSSDGRSLELLSKTDFSALKGLSGYASIIMSRPDLHALLLSHVPSHKIHLGKRVLSMSQSDDNGVLVRTSDGLTRECDILVGSDGAYSSVRQSLYNLMKKEGCLPSSDGEDMKVCDMSVLGTTNSIDPSIVPLSKDEFSRCDIVLGYKNSYSVSFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MGW7</accession>
    <name>A0A9P6MGW7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006577</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003255">
        <property type="protein sequence ID" value="KAF9999394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MGW7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9999394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="221" mass="24804" checksum="45E055328C23D3A4" modified="2023-09-13" version="1">MVMIEPRFNTKTGEYIILWNDIKAVLRNAQHVQRGKIAVSFHTDDDFEFIKPLRFSTFSDNVLDVVVDTQEAGIAIESLMMQDPPVYTSGPSPANSNYNEKSKKAQASAASFPENRRDDTQNTKTKGDSHDLDESKRNSTSLGPKSTDQAQKPFSDSNDDSHSPCNQPRPGAKRPSDGFSIDPYDVEDMNEDHIRGLAYYEGENIRQDHVKALVYFLKAAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MH10</accession>
    <name>A0A9P6MH10_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_006526</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003222">
        <property type="protein sequence ID" value="KAF9999676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MH10"/>
    <dbReference type="OrthoDB" id="2398144at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9999676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="114" mass="13025" checksum="AE36AC4036899239" modified="2023-09-13" version="1">MTASEPIQIIRFSPHFSPPINGIRNANSNRNNYSTMSNNAPAVTYKIRACFQDPVTKQYFFLWSHVQAVIKDAVFAVDADDGTLVPFMVNETYEEYVIFLSQCILLILHHDKLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MJG5</accession>
    <name>A0A9P6MJG5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005514</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002716">
        <property type="protein sequence ID" value="KAG0005034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MJG5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="431"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="457"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0005034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="543" mass="62345" checksum="262C2F4D9166D386" modified="2023-09-13" version="1">MSILRRHGTNVVSLDYVHAHKSTFHFIRTYCPLVQSLSLRFDNRSPRITYLNLEEFFLSMLHLKILHIRFDASQFSPAMFWSLSQLPKLCRLSIDVFYGDPHNSRHYPPDAYMTILDCCPSLDDFTVYGQFLEPIDSTELFHKTSFIQWIRKKIQFQRENAPSTPHEAIASPMHLRSLSRGSTISRLRRSSKAKNNHIKVPLNSEHKIKKLELRSPRMDDRVFSKLVSCCPLLEELTIDGLWARISAASWQTLSAQCPRLRCLTVRDSGVVHYLPSIPSLLTLFPQLESLTLMSLEFKADPDLSTLGIKLREIEQQTGDRHPLKHIHFSGSILRPIKLLLDILTQSSTVESLSVGFTFNTLRVLQNEPDTPYDFNKEWLCYDSLHHLDLTSIWFKNRDAFKKFFIQVQRLTRLKSLWISVCQLREARSMGSTGRRRSFRPLDRSLSSADNNGGGGSSSNSNNNQVRGSGRRSRSFFSFSTVETIRIGTACYQSKKISELPIVYDEVVDIIEAAPMLKQLELTHMSESGTVKRLSLEYAKIKIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMK2</accession>
    <name>A0A9P6MMK2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_004234</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002181">
        <property type="protein sequence ID" value="KAG0007782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMK2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="166"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="194"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="587"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0007782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="814" mass="90935" checksum="E492A56ED87106A1" modified="2023-09-13" version="1" fragment="single">MSISIDPQEGGPIEGLFGGQVGQRIGHLVEHGDEPSRARRTSESEGRLLGAQRSVSAPPLSPRPGGSKSNWIPGLSWIPWNRGRSSSSSNPYRSQINNNNYRRGSSWWGSRLYNKISFGILPTTSNTATSTAAASKPGVIWYIRINMSALVAFAVGLVSTKRRKSWFLSLILVSLVLTLLSGGYLLSQFQHQQDNMPPAVSVPGSDGGNLLVDPGTGGPRRDRTRGKKHKAPKKQPTSQTRKNETIPAGGQKIAPNSPGSGTGNTDDTNVTTGTRICNLEDVADGQWTHSAQGQSPEWGPNQDMSWTGYGHNGCRSNIWNERYLLTPTVTNDTTSKHRSTSTLQRDWDYAYHLKNSLWQPAQKQRRGQEGGCKQPEMDVEDFVEVLKRAPLVMIGDKFLEQEYLTIECLILGMQGQLVYDYRLENNKNSVDEKTMKGALDYWIESETPPVVEFKVAPQFVAKTDGTSSTGKNRPAVYRKAKPGQMRLVDRASNLTLVTFIRSDVLWDSEMLTRQTTKHTLKSIPQPSNLDAAGGLHPDCKLAGTVLLCEPARIDFAHDRRQEGYKPTKQSTTRHWWQWWIGADGNTETDQLQSEDVDGKDVEDSEEDMSFGSDFDHDMINLEWVQSLDDIVQDAANHRTKEVAGTVERKPVVMISNGHFWEYDPQDAAALFSITKGEGVKMKKRALSKAEQDQLRETQIKRRKLLRQRYTMVVTNVLDYIKATYPDLRVVVQTSVRCNTCEAVVDTKEPVGVGNQEAALLNALTKAVVARMQDPLYSFLDTTFLRLFRDSVASKRYCNNFMMPGPLDTLVHHLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMP1</accession>
    <name>A0A9P6MMP1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004561</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002311">
        <property type="protein sequence ID" value="KAG0007530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMP1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0007530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="264" mass="28622" checksum="1342FDB81A2BC0CD" modified="2023-09-13" version="1" fragment="single">MAIPKQWIDEDNVTKSQEIETAASMNTVDSSSLELKSADDSMVFGDASGNDPSDPAVDRPTSVPALASRGALDNGMSLPSSQDSCLDMTPHRLNEQIACSISADGAAKSAPNNLSDARKDATDVVRFSTEEIGVIDSSFSHVPAAMNGMKEQESTQSLKLKIENNRENGSPRTSGEMALPDSSDIIKPERNAYKIVPISEGDERKIDHELQLRIDYWRKALADAPVLLGLPTDRPRATQQSAAYSHLPIRFDAQLTQLLKNLGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMY7</accession>
    <name>A0A9P6MMY7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_004310</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002209">
        <property type="protein sequence ID" value="KAG0007731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMY7"/>
    <dbReference type="OrthoDB" id="2593073at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090575">
        <property type="term" value="C:RNA polymerase II transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050936">
        <property type="entry name" value="AP-1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021833">
        <property type="entry name" value="DUF3425"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621:SF6">
        <property type="entry name" value="AP-1-LIKE TRANSCRIPTION FACTOR YAP1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621">
        <property type="entry name" value="TRANSCRIPTION FACTOR KAPC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11905">
        <property type="entry name" value="DUF3425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="4">
        <location>
            <begin position="83"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="179"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="23"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="49"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="82"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="200"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="226"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="259"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0007731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="557" mass="62302" checksum="26494F8770986F15" modified="2023-09-13" version="1">MRQLPQLRIIQQQFDRVDKRPYSNVSSSKSTNKPHTSEDDDDTNDGDHNATSNDGGHSSSSEPPFKIRKKPGRKPNPASPAVRKEQNRAAQRAFRDRKERHLQEMEAMIKELKETNSQITQRLEKDTQHFKSTMDALQNENYYLRQVVFSFETALNKGGNITILQEVKAELYRSHYEKHSTKKLSGVPPSSRETRPPAPATSSIFSPDSNLPFQFVPETPRRSHEQTPVASTSSTFSNSAIPPILSTPPSPPSSFGDVSTSPSSNSKDSPPTSWSGPDPDDETVFSMNNDILYKAPPLYCMIDPNGGKLLRSITPCEPPSPPRPLFTRTEYITSVRSVFDELQSSLFPPGTLQSVIHTELASPQEVVSDITMLDQLHDRRPLKDPVISPGHTAITMFASLDAPSPCAPTSILDDDNNEFVLATPSLGLDDGLKQNVIPSKRLQLEIKVLASAPPAVDPNIDPKIYALPHDSRIDLIPCPKLRAQLILHQKKLDLEDLCQLLINGARCHGHPLDPHSWELPEEFFDRYGFLLGEEMLRHRNKVWPKKDEPQLETPIAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MN63</accession>
    <name>A0A9P6MN63_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_004138</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002140">
        <property type="protein sequence ID" value="KAG0007872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MN63"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43503">
        <property type="entry name" value="MCG48959-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43503:SF2">
        <property type="entry name" value="NEGATIVE REGULATOR OF SPORULATION MDS3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="BTB" evidence="4">
        <location>
            <begin position="493"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="229"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="277"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="699"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="749"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="9"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="234"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="749"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="759"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="797"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="833"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="851"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="874"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0007872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="874" mass="95774" checksum="A2D208EA35F93BAD" modified="2023-09-13" version="1" fragment="single">MPAPAPGLQSISDLTTTSRITTGDIPPPLVGATMTIVDDKLYLFGGRLIQTRQMTNSLYILHLEEFRWENVSEVVNVTPTKLPVGDPGAEENEMSPPPAERYFHSANPYKNMIVFFGGMGPSPNLNDGQQQELVVYDDVKVLDLEILKWRQIRIPSSPHAPKPRYAHLSSISGNKLIVIGGQDISNQYIEEINVLDLDSWQWVSSMPFDKHCGSYRSIAVSGSSQGSAIPQIGSEVDQSSTSSQLSPTSVDGFPTSYLRKGSTASSLHYTPSLRRSSSNLALPKKGGPMSRLSGSGFGTSPPSDQRSSIYRLSYIVPPTPVQQEEHPVYLYSNFNFSDVKRELQVLNPPQFQVQDHSQSMSGNLLPPGLRFPTGAIAGQYLLLSGTYLTNTQQSFSIWALNLTSLVWNRIDTGSVFNSGSWNRGLLLESSNAYLVFGNRDRSLADDYQNRQTNFEHVSIVDLEAFGIYQHPPTTMTQTAQELGLGLLNDPAMADFEILTIDGQRIPVNSSILATRWPYFGALLREQEDLDASASVSGTTLEGTEFDSDMFAKRTLSLPEPYTVVLAFLQYLYTDHLVTAQQHHSQVLSQLLLLADMYGLDRLRDLATHALHQMLNMSTAAMVYETAALSQQTGLQIRSLKVMIAAKKMLQQQQLKLQQQQAHSQSISAEHAWRTGNEQHQDDYNGYNSNGYMSQQQNIQGIFQPTPPPPLSPGSMSTSPEYHRLSMSGAQGIALPHPMVRNRNSQLGSIQPQHWNTEPLTPPPASPPPPAAAPPKSAPPAKQSFFSFPGSKSKAEKQAASSSVSSSGASISGSSSNGNSRKIPAFANMGVSPITAQSDTASVRSAKSTGSDPDKKKLDEQHKREVMLRLLDGSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNB3</accession>
    <name>A0A9P6MNB3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_003878</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002052">
        <property type="protein sequence ID" value="KAG0008082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNB3"/>
    <dbReference type="OrthoDB" id="2386345at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0008082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="641" mass="73175" checksum="508A78BF95231A08" modified="2023-09-13" version="1">MHTPGEATAHALSLHEIRTHITQFLSLSDITKAIRVCRQWNDFFNPLVFNAFRIVGNRKNPPLEVLQKYVQYIHRLEFGALSVETPPEYFFLQGCSNLTKLAYVIGNVPRYRVSDLLEKNIKIPMELYDPNGDTKDLDDSDTGFGLFDNFDFVITAKQDPSQPLTSMGLQPGKATTLHPWELARYFVSVHASSLREITLTGSTPTLAFWETLARDCSMTLESLTLASGRIEQRAETAFWMACRNLISLDLSCQFPSCGRNEPTLHVKSTSIPWLDENRPHFFPRMKNIVIRIPQVHPLVELLKNSPNLESLDLTLSPNNIVRVLETLTTIARFDLYSSASSLPSSSTLVRYTTTMSTGEIWTPFHSMSIYCWDISDQQFSALLRFTTRVVNVFACDSGFGDEAMQVMHERFHFMTVREMNLDKCPNVTSKMVNTLLVSCSALEALSADRLYVVDMVQDGSQPWACLNMRELCLNIDLFDPYQGHIESADNDVLEEEGSENDEGANVAEEAGKSMEALQVAERQRLIIAQLAKLRKLKVLCTNRECMDSQDNGPTECVEFILEKGLDQLARLTQLEEIHFSGLERPPRLSEAEWMLKHWKQLRIVHRDRYTVYFDRWDHDLRVMFAAPDGIDNDQKEFDVFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPB1</accession>
    <name>A0A9P6MPB1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_003385</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001891">
        <property type="protein sequence ID" value="KAG0008489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPB1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035673">
        <property type="term" value="F:oligopeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004648">
        <property type="entry name" value="Oligpept_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00727">
        <property type="entry name" value="ISP4_OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22601">
        <property type="entry name" value="ISP4 LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="215"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="285"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="359"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="414"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="441"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="524"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="591"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="638"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="667"/>
            <end position="689"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0008489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="724" mass="81703" checksum="735EF139D6306AB6" modified="2023-09-13" version="1">MSEQKQEYITEKEHVEEKFDVERTSVILDEENSPIPEVAAIVPNTDDPSLPSLTFRFWIMATGFSVLISFCNQFFWFRQDPISIGMSVVQLLAYPLGKFMARVLPTGILNPGPFNIKEHVCIALAANCASGTAYAMDIIVIQRVFYGQNFGFLANFLLILTTQLLGFGLAGVLRRYLVYPAAMVWPANLVQVALFSTLHKDEDLARGQWSRYKFFMIAFATVFLYEWIPTFIFPVIGALAWVCWIKPESIVVTQIGGPSGLGFGVITLDWNVITAWLGSPLVVPWWAQVNIGIGFFLIAWILVPITYYTDVWEAKKFPIVTPGLFRDNGDSYDATAVLTSGVLNETLYEAYGPLRISTFFALTYGIGFAGLTSMLSHTWLYHRHKLVAQWKQSREHSEDIHHKLMQAYPEVPDWWYIAIFVSMIIVAIVTCEVWDYKLPWWGVILAVVICCIFVLPVGLITALTNQMPGLNIITEYVIGYALPGHPIANITFKTLGYISMTQALTFVGDLKLGHYMKVPPRSMFWAQILGTLIAALVNLLTADWLLSSQQGVCTTSVDFPCPYAGTFYSASVIWGVISPQRMFGSGSMYNVVNYFFIIGLILPIPFYYLKKWVKSSWVEFIHLPVLLTATGMMPPAQAMNYTNWLVMGFIFQFFARRYHAEWHLRFTYVLSSALDSGTAFCVLISFFIFTNRNVSMPNWWGTRTDLCPLDGNSYTPPAAIPTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPK9</accession>
    <name>A0A9P6MPK9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_002389</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001587">
        <property type="protein sequence ID" value="KAG0009442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPK9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="92"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="136"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="4"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="94"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="145"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="165"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="181"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="191"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0009442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="210" mass="23977" checksum="DCD691FD375E8E86" modified="2023-09-13" version="1" fragment="single">NDVLLQKLRRINEARRAIAADEERLAEMERAMKEREENLRRSMIEQEERENELRESIQRNIKREQELVAIQHQELQMSQASEIYQNPFASNEPLIRDYSDNDSQHDQIQQTTAAPEVSSRAANAILRHDLSVNHQENLNPFEDPSSLLENASSSSTRSSVHGNDDVDAFADAEEQSMTVHDDDDDLEWTEAEVGSVGSEESDESWGSTSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPN2</accession>
    <name>A0A9P6MPN2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alcohol acetyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_002461</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001608">
        <property type="protein sequence ID" value="KAG0009372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPN2"/>
    <dbReference type="OrthoDB" id="2150604at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052058">
        <property type="entry name" value="Alcohol_O-acetyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010828">
        <property type="entry name" value="Atf2/Sli1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28037">
        <property type="entry name" value="ALCOHOL O-ACETYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28037:SF1">
        <property type="entry name" value="ALCOHOL O-ACETYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07247">
        <property type="entry name" value="AATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0009372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="524" mass="59041" checksum="26ADD84566DE6A53" modified="2023-09-13" version="1">MALQFVRPLDMYARYCVASSVINHYKNFLIAHKIQLNPTEQTKLGGPNYPSWKSPYEWAQLLLYPMAYLLNQHPSLTVTIGDHLGNIPVYLRLKYIDLHRLIRVAPIKTSTEIGRVIEQEHNISFNFSDNTSPLWRLVVAPIEDDESSFYLIFSFHHAICDGRSAAALTEQLIGQLNSKPRQPENTPFSSPYGTTRISITSNKPIPAPMEDRFQLRLSVCTLVKEVAKQFPVPGFVRRAFETKYWAGDIDVSPEAPNETELCLLQLTTQETSRVVQASRRHSTTVQAILYAASVFATKSVFMSNAEDRNSAEETITFGTMISLRDRVPEPISPTDQGNYIAIMPHDGIYIREKSSFWSTASDYRKEIFETISTPQKVRSLMKDLGMMRCLPKKAGAWEKAIKSPRMQHGRSMTIIMSNLGRVLSQSQNNQSSVSGEAPQYLVDDTIMSQSPFVNASAFLISAATTNGKMTISTAWQKAAFKERARGDLFASEFKRILLEAVDDGAETYLFEDAKRTYDSTVTLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MR33</accession>
    <name>A0A9P6MR33_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001883</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001442">
        <property type="protein sequence ID" value="KAG0009990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MR33"/>
    <dbReference type="OrthoDB" id="2571149at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0009990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="323" mass="37416" checksum="7488444D62AAEA10" modified="2023-09-13" version="1">MSAIPFWKHPDHRIPTLGLYRALLKASLALPKTCQDQPGRQRRPIPIKGAGPPGSNEPLPAIKRGYIFALIRDSFRANRYSTSPRITRGYLLEGEEALEKLEKARDGDRAIRRELRDMVNGRTGRLKEVIDHLNDLINFEPGETTQRSRYQRLKRAHEQVWDVRTQSSILRDPYSYYRITLKPSLFTFPPELDYYPPAKYPNQMKNQRGKFKNSGGVFLTEVTTSEGSRFPRIRGGTQPEWISMMLKSRVKKSVKRVNEWKDLEEKKAMMEVEEKFAASLGVKDSGYVEYLDTRLQSLKNLHWRKKFDTNSRNGVEALDDIST</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRG3</accession>
    <name>A0A9P6MRG3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001269</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001288">
        <property type="protein sequence ID" value="KAG0010670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRG3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043141">
        <property type="entry name" value="Ribosomal_uL10-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047865">
        <property type="entry name" value="Ribosomal_uL10_bac_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11560">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L10, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160369">
        <property type="entry name" value="Ribosomal protein L10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0010670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="117" mass="12509" checksum="40B85AB7AE1DE8B3" modified="2023-09-13" version="1">MSVPELIQLRTEFAAAGAEMTVVRLGIFSAALRETRYANLAPLMILLGGKVDDALVSVEDMKKMVEMPGIQTLRSQVAGLLSQAGGGRLVQLLNMNPTLLLMNLDAHAKSGEGESKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRL5</accession>
    <name>A0A9P6MRL5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Succinate-CoA ligase subunit beta</fullName>
            <ecNumber evidence="12">6.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">TCA9_2</name>
        <name evidence="15" type="ORF">BGZ80_001597</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate metabolism; tricarboxylic acid cycle; succinate from succinyl-CoA (ligase route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Heterodimer of an alpha and a beta subunit. The beta subunit determines specificity for GTP.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the succinate/malate CoA ligase beta subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.-" evidence="12"/>
    <dbReference type="EMBL" id="JAAAID010001367">
        <property type="protein sequence ID" value="KAG0010307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRL5"/>
    <dbReference type="OrthoDB" id="1552at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042709">
        <property type="term" value="C:succinate-CoA ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004775">
        <property type="term" value="F:succinate-CoA ligase (ADP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006104">
        <property type="term" value="P:succinyl-CoA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.20:FF:000002">
        <property type="entry name" value="Succinate--CoA ligase [ADP-forming] subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.261:FF:000001">
        <property type="entry name" value="Succinate--CoA ligase [ADP-forming] subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.20:FF:000004">
        <property type="entry name" value="Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="entry name" value="Succinyl-CoA synthetase domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00558">
        <property type="entry name" value="Succ_CoA_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03220">
        <property type="entry name" value="Succ_CoA_betaA_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013650">
        <property type="entry name" value="ATP-grasp_succ-CoA_synth-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017866">
        <property type="entry name" value="Succ-CoA_synthase_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005811">
        <property type="entry name" value="SUCC_ACL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034723">
        <property type="entry name" value="Succ_CoA_betaA_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005809">
        <property type="entry name" value="Succ_CoA_ligase-like_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001913">
        <property type="entry name" value="PRK00696.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01016">
        <property type="entry name" value="sucCoAbeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11815:SF1">
        <property type="entry name" value="SUCCINATE--COA LIGASE [ADP-FORMING] SUBUNIT BETA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11815">
        <property type="entry name" value="SUCCINYL-COA SYNTHETASE BETA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08442">
        <property type="entry name" value="ATP-grasp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00549">
        <property type="entry name" value="Ligase_CoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001554">
        <property type="entry name" value="SucCS_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52210">
        <property type="entry name" value="Succinyl-CoA synthetase domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01217">
        <property type="entry name" value="SUCCINYL_COA_LIG_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 12 15" id="KW-0436">Ligase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="3" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="ATP-grasp fold succinyl-CoA synthetase-type" evidence="14">
        <location>
            <begin position="19"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-citrate synthase/succinyl-CoA ligase C-terminal" evidence="13">
        <location>
            <begin position="285"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00063570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU361258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF08442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0010307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="427" mass="46334" checksum="72DE2AE53B62E500" modified="2023-09-13" version="1">MFQPRVNLAAQHQKRFLSIHEYLSMGLLEKQGIKTPPGSVAKTGAEAYAAAEKLGTEDMVIKAQVLAGGRGKGTFDSGLKGGVRTVFSPREAQMFAEKMLGHKLVTKQTGPAGKICNSVYICKREYVRREYYFAVLMDRKSQGPVMVASSQGGVDIESVAAEDPKAILQLPIDINKGADHAAVRNLAERMGFTPKCVDQATDTMLKLYDLFIQKDATMVEINPMAETVDSEVVCMDAKLNFDDNAEFRQKDIYKLRDISQEDSREVAAAKYNLNYIGLDGSIGCLVNGAGLAMSTMDIIKLHGGEPANFLDVGGGATAEQVTEAFKIISSDPRVTTIFTNIFGGIMSCRVIAEGIIAAASTLQLRIPLVVRLQGTEEEEAKKLIEKSGLHIITADGLDDAATKSVQLSKMVNMAREAKINVSFELPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRV1</accession>
    <name>A0A9P6MRV1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Septin-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_000678</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001145">
        <property type="protein sequence ID" value="KAG0011456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRV1"/>
    <dbReference type="OrthoDB" id="5340910at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030379">
        <property type="entry name" value="G_SEPTIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18884">
        <property type="entry name" value="SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00735">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51719">
        <property type="entry name" value="G_SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Septin-type G" evidence="3">
        <location>
            <begin position="16"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="47"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="65"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU004560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0011456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="341" mass="39077" checksum="9D180979C10DA8FD" modified="2023-09-13" version="1">MANSHYLLANPFAGQNIGHLRLAVVGDSGVGKTSFARQFVETLPEVLSHDWESGDNGNNNKDNNEDKDNDNDEDQDYTPTDALTEKFASTMMEIPWDNMETDDEVPARNLVFLDTPGYGSVIDARTNFNLFMSYVSQTFEEKSRKISPFIEVSNNELMRSLVTGVGAHRFIDVCFYLIVHRLKPIDIEYMRLISEKANVVPIISKVDTQPEEEVKELKVHVLKTLREQGVPIYTFRIDYDRLINMAETGQFGGPPFAVSNVPAKPVSDDIDDQIPFKHGANELPLLRKLVLETQITNIRQFTVKKFINWRGKHMQQQQQQQQNLQQPYFHNQQAFPQQTIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSA7</accession>
    <name>A0A9P6MSA7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_000714</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001155">
        <property type="protein sequence ID" value="KAG0011404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSA7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.15.10.10">
        <property type="entry name" value="Bactericidal permeability-increasing protein, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027842">
        <property type="entry name" value="HAM1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045967">
        <property type="entry name" value="HAM1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31138">
        <property type="entry name" value="CHROMOSOME 19, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31138:SF1">
        <property type="entry name" value="PDZ DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14613">
        <property type="entry name" value="HAM1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19343">
        <property type="entry name" value="HAM1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HAM1-like N-terminal" evidence="3">
        <location>
            <begin position="13"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="domain" description="HAM1-like C-terminal" evidence="2">
        <location>
            <begin position="406"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="561"/>
            <end position="582"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF19343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0011404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="582" mass="66457" checksum="D7F3D553FF5A5913" modified="2023-09-13" version="1">MASLRDMRQHPRKDFAKRTASKLKNQFNRRDNETTAIIQAKTSEMQGVASDYANQVLTKERQQVIIDRLKLIVGQIQSDPEYQTTIDSIIELVGNWRQQAQDPASSVSTEAGKVVNDPNVAAAATEFKTILERWAQDYSLDPMIDLIKKLWQRARQDPQLSQYLDNVSYFITLVVREPNYVTSDATIDRDVELLLDQGQTLFKAKYRLETDDLLSEVQAYMERLTTDPMAQQVAENLQKVSNDLFYDKKGRLVFKPHLFDDFRYVILPSLRDAFQFIPIPRIEYSDLKIDLMLDNMTLTSTDLIPRLFEIQMNNSIRMVPRGKSKLSDTNKHEFLMLIQGMEVSARHVDYYVKTKEGFIYKDRGVADVLIHRRGMDIRVEGRKTPSDEDDDDDYRTSMITFDKVQVKINSLNVKMRQSEHPVMNTFAQPLIKTTVKNAIAHTIEAELKEALISGDRAVATAVRDARIKTGKNTFGALIETMASLVQNKLSPSKGRRRSSGQYNRTSRVIFDADGFCVLDPVKHMELKVGQPLVEDQNEMANMEVNAPWVSSAFDMHGLQTNDSGTARNELPGMRRTHGTLAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSH3</accession>
    <name>A0A9P6MSH3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_000747</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001162">
        <property type="protein sequence ID" value="KAG0011360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSH3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019900">
        <property type="term" value="F:kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019722">
        <property type="term" value="P:calcium-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045198">
        <property type="entry name" value="CNBL1-10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23056">
        <property type="entry name" value="CALCINEURIN B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23056:SF110">
        <property type="entry name" value="CALMODULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00036">
        <property type="entry name" value="EF-hand_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00450">
        <property type="entry name" value="RECOVERIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="205"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="241"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="34"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="315"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="434"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="614"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="34"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="53"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="71"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="91"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="320"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="343"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="369"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="472"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="516"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="541"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="559"/>
            <end position="577"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0011360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="732" mass="79562" checksum="DBEEA034589D96CE" modified="2023-09-13" version="1">MASTSTPSPIPFLLLGLVTGGALLYVSYWVWPPSQRRNSNSSRSSRRSGRRQTANSGRNTGSSSASQGGLRRSNATRRSNTNRQQQRQQSSRRDDSRRYHSDGTSSDEEPRRGRGYINDSEDGDTTDHEYPSRAKKLPPFYPGVPQGNTTTPDHMLQELLQKTHFDNVELDAMYNQYLSLSTLDQEGGGITRLTFEQALGPLGLEKNLITDRIFKFFDQDNDEIINFKEMACGLSVLCKGNFDEKIDFAFQGYDLDGDGYISREELHEMFKAYFYLSMELIRDVVKTMENDMISNFEYQPGMPISSTFTAPIPREIGVRNNNNNGNNNSNNNNNSNNNINGRTAEERRRSREQASLQAGWPLSAIPSADSGSETPATSPSIHGLVVELEDQFIEEVHEEDVAQIEGADHLVDGGSLPSGTYGLFGSDAYIDEGEEEVETSAATDGGTEKSQDIGSEVASSPVPVALEHENDVSEGEDSGEDSGVESSGWRADALSPTHAHPHDPQISPLSPLSLEVNPQVNESQATANGQSAASRTADPQGSSPSEGSSSRPRKDQPLPATTSSPHVAPPNISNTNLYWDRPHSQTHHRSGSAYFQNTPAAPPSLAPALAIGFGLSQGSEPQPAGTLGSSSSHRENSNSIGVRRPSLGTPYHSFASTSSAPTGSYANASYFSSTFPVMESISQDAIQEMVDKTFTAIKNPSKPGYITLEEFRAYVLTDAGILGWFDALGSIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MT92</accession>
    <name>A0A9P6MT92_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_000314</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001062">
        <property type="protein sequence ID" value="KAG0011947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MT92"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="180"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="320"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="266"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="184"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="194"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="217"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="324"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0011947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="362" mass="42202" checksum="14EE4A51D6893694" modified="2023-09-13" version="1">MELLVFLGQRYQMMQGLENIKTQLSTYFLFRNEYHSLFRNEYHSLFRNECHPLFRNVNPELLADPETWALLDGPGEKNDHYMPKKVVYENLAEKVNTKFSTEEEPVNLDGLQIKNKIENMKAQWKKAKKFHDRTGNGNLPEIDLRKQVADICCFFYVLQEIWSASWSISPRDPIQCTGNLTRPIAHDPGNDARGEDEETAVEQEDVGTEPETSRQAIKTKKQKRGREHVDMQTLLEDTFKAAEEAHDLKRQRLEIDKRRFELDERLADVQIRKLEWEMELEKKKAEAELERQKMLVEVEHLKAMTMLKQAEAVIVIESKRRNDTATVSDSPLDPSNTRSLPRSPSKYASIIANYAAKYNQSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTH4</accession>
    <name>A0A9P6MTH4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Glutaredoxin 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">GLRX3</name>
        <name evidence="8" type="ORF">BGZ80_000331</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters. Binds one iron-sulfur cluster per dimer. The iron-sulfur cluster is bound between subunits, and is complexed by a bound glutathione and a cysteine residue from each subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the glutaredoxin family. Monothiol subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001067">
        <property type="protein sequence ID" value="KAG0011915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTH4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015036">
        <property type="term" value="F:disulfide oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03028">
        <property type="entry name" value="GRX_PICOT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02984">
        <property type="entry name" value="TRX_PICOT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000012">
        <property type="entry name" value="Monothiol glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000092">
        <property type="entry name" value="Monothiol glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033658">
        <property type="entry name" value="GRX_PICOT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004480">
        <property type="entry name" value="Monothiol_GRX-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10293">
        <property type="entry name" value="GLUTAREDOXIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10293:SF73">
        <property type="entry name" value="GLUTAREDOXIN-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="7">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00055846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0011915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="277" mass="30347" checksum="029B657E526BABE3" modified="2023-09-13" version="1">MASTNYIDLTSDQEFATIFDAKSSTVYALNFWASWAPPCTQMNQVFEELAAKNSALKFIKIEAEKFPDISEEYEIAAVPSFVIVKEGKVVDRVEGANAPELSKTIAKYSKSNSYTTLPAQSSAAVGNGGASPSVAAPPTLSPEEMSARLKELTSSASVMIFIKGTPTAPRCQFSRQLLEILTAQNIRFSSFNILADEEVRQAMKTFSDWPTFPQVYVKGEFVGGLDIVKEMVATGEFQALVPAEKDLKTRMNELIHKAPLMIFIKGSPETPRCGFSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTZ5</accession>
    <name>A0A9P6MTZ5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Protein PNS1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">PNS1_3</name>
        <name evidence="10" type="ORF">BGZ80_010956</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">Probably involved in transport through the plasma membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the CTL (choline transporter-like) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000821">
        <property type="protein sequence ID" value="KAG0013635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTZ5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007603">
        <property type="entry name" value="Choline_transptr-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12385">
        <property type="entry name" value="CHOLINE TRANSPORTER-LIKE (SLC FAMILY 44)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12385:SF4">
        <property type="entry name" value="PROTEIN PNS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04515">
        <property type="entry name" value="Choline_transpo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="149"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="177"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="204"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="243"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="283"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="308"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="346"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="407"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="444"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="24"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="24"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="42"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU368066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0013635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="510" mass="57348" checksum="2631904CF9210F72" modified="2023-09-13" version="1">MAQNAPPVQQQQYMYNVQQQPMYNPHHQQQQWGNHQGNHQNYNPPTSQLNHAQPMSGVMPPPDYESAQYGVVNPDSGLPAKFNPRPRYTDCWAFVLFIAQLAAFIVLSVFAISKIVDDANQPAMDYTQPGQTTPYFSGNSNNFFMKQGLIAILIAILIGIITAVIYFIIAQAFPRQIIKLTFALSIMAQIGIAVYYFVRQEWMPAIFCAVFALLYAACWFFWKSRIPFATEMLRAVTSVSKKYPATFVMAFLGLFIQIAYSVYFMVVVTGCYEMYYDRNTRTAPAKLKVLIFFCFFSFYWTSQVIKNIVHVTVSGVFACYYFLMGSPQVQTVRAVAQVLRMDGDGFLAFIACLIDCILACLQGLIAYVNIYAYCQVAIYGKAYIPAARDTWKILKDRGIIQIINDNLIGNVWVMGALMSGMLSALGSFLYLWYATPGFDNNDSIIYVILTMAFVMGFQMLFTVGVVIDSGNATTFVCLAEDPAALATTKPELFEKIRATWPAVVEGVNTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MU19</accession>
    <name>A0A9P6MU19_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_011004</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000830">
        <property type="protein sequence ID" value="KAG0013554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MU19"/>
    <dbReference type="OrthoDB" id="2409114at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="160"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0013554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="457" mass="49897" checksum="BC4621B9EEAA0D4E" modified="2023-09-13" version="1">MVSATSNEAPAGGQSIVKVKAPSPKAGFRNQSLLIRSQPIYLDLDAFPAPTSPLPIPKQPTPPSRGPSCTPPSTPSKVISEKPSSPTGTMPNSLRPPPRPRSIVSQLTLSKPPSESLPPIPTILHSNDNLHISSTPTSPTTPTTPPLYPSFTSRYEDSNPSRPSYSIRSSSLGRLHGNLKNKTPRKTSNASISLVQKETPRGRPAQTSATPLQKQERSDSISNMEGLINKALAPRPETNEEERQSLVNIELPSRPMGLVATRFYGIESSMRWREGVDPIQKRFASSNGSWRCQDRFAIFFRPGDQIGPDQVVTKTFWSEAWPYPIETILYGTGTGTINSLSSNHGLEVGHRSNQDGELSSRLRTGLRLTSSETQLKNAASFPPTSQSKDPRYITSDGVQRIAKVTIPMPDVPIDHVDLVKAPIKVELRIFILEAPLRIHASAFLLSRTVAGTVELYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUH7</accession>
    <name>A0A9P6MUH7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NodB homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_011008</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000831">
        <property type="protein sequence ID" value="KAG0013549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUH7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051858">
        <property type="entry name" value="WD_repeat_GAD-1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16017">
        <property type="entry name" value="GASTRULATION DEFECTIVE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16017:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040364156" description="NodB homology domain-containing protein" evidence="5">
        <location>
            <begin position="24"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="domain" description="NodB homology" evidence="6">
        <location>
            <begin position="1"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="360"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="461"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="568"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="199"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="250"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="725"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="804"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="199"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="251"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="268"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="290"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="306"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="336"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="737"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="813"/>
            <end position="830"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0013549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="830" mass="91815" checksum="A0924588ED60D7CF" modified="2023-09-13" version="1">MSFVRLSMATILLVSPYWAPVLAGAQSAIIYENCRVANTAALTFDGGPWIYSKDIVDILDAAGAKATFFIGSSTWSFRDMTTFSEQEIIDKASKIDKALVKISGVLLATVRPPYGSYNQLIQDVMSSRGQAIVLWDMEIRDSTGATPDQSKITIDQVVSKAPSNVLVELLEIETTAQVVLPYAIESLVIICGYAHPEKSDHTTPKFKGKEKDDFDIPNKTLTSKQPKVAPGPRKAPANEDAMDALRAFMPTSFGKQKTSKSSSTQQYERSKRSEDQDQKETLASASSTATKDKDQEKAVKSKGAESDGDDDDDDDDDDDDDDDDDDDDDDDDDNDDVKGADIDSDRPDSSVIPISHEIVLNEHSKTISAMALDPAGGRLVTGGYDFNVCFWDFAGMDTRFRPFRSMEPCGAHQIHELKYSLTGDKILIISGEAKARVYDRNGVEIAEYQKGDPYIRDLRLTTGHVAALTSGAWHPYTKDRFITSSADGTIRLWDVENIRKQVDVIAYKTKERGGRTSVTALSYSSDGKLIAGAAADGTISLYPSNGPFLRATHTIENAHVKGTETSGITFSRDSQHMVTRGGDDTVKLWDVRNLKHPLSIAEDMVSLNSEVNVIFSPDERLILTGTGVKKNEGYGKIVMMNSENLEIVRTVSVTQSSVVKVLWHDKLNQIVAGNADGTARVFYDPEVSNKGAKLCATKTPKKRAVDDYEIDRPIITPHALPMFKEDKTRSNKRKQEKMRNDPVASHRPEMPISGPGRGGKVGQSAIQHVLTDVVKDRMREEDPRAALLKYADVVEKDPQWITPAYKTNQPKPVYDERVEESEYRELKRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUW6</accession>
    <name>A0A9P6MUW6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ras-related protein Rab</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">RAB32</name>
        <name evidence="8" type="ORF">BGZ80_010959</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">The small GTPases Rab are key regulators in vesicle trafficking.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Membrane</location>
            <topology evidence="6">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000822">
        <property type="protein sequence ID" value="KAG0013618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUW6"/>
    <dbReference type="OrthoDB" id="48625at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04107">
        <property type="entry name" value="Rab32_Rab38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000222">
        <property type="entry name" value="RAB32, member RAS oncogene family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030697">
        <property type="entry name" value="Rab29/Rab38/Rab32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47981">
        <property type="entry name" value="RAB FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47981:SF39">
        <property type="entry name" value="RAS-RELATED PROTEIN RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 6" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 6" id="KW-0636">Prenylation</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="190"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="197"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0013618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="216" mass="24476" checksum="AFE7D260F46EEA62" modified="2023-09-13" version="1">MYEDSPYPIDIREYLYKILVIGDLGTGKTSIIKRYVHNIFSNNYKSTIGVDFALKVIQWSPDTVVRMQLWDIAGQEKFSGLTRVYYKEAVAALVVYDVTRPKTFEAVPKWKADLDSKVSLPGGEPIPVVLLANKTDLQDASSGGLDTEQMDQFCEENGFLKWFGTSAKDNSNIEDAARYLLEEIMKREAEHAHHQEQNAMNDRIQLNQPSSKEGCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MV08</accession>
    <name>A0A9P6MV08_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_010818</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000797">
        <property type="protein sequence ID" value="KAG0013829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MV08"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="194"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="151"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="280"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0013829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="380" mass="41117" checksum="1A8FE8D7B564E666" modified="2023-09-13" version="1">MIEKHCQHLRYIKLGPNLLSTSATMTSSDLNQDENRLQVLYRNISNMGGGDQNNLNNGVQQQDMGGVMELSLTGFQQQGPHETLQLVHTEKRGGALGGHNGTNIGQDDQRGNGMGTLGLGLQIGMNGMLILNGVDASSLPSNNDGQMFVRQQPNQNNQGNSSEIDARSGFISQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHMMMNTHHRSNLSSSLSGPTVHTSMAMSTPGSSATVSAGLMSPIGSSPPFSSTIPTSSSSMIPYTYAPNGNNVDSISQHQQQHQNQHQLHQHHHVRAQPFQHQGPTMTLLSVKTEGSGLGPMMTGGAHMGGGHPGVVAMTMTMGNPSEFEEAMGLGMAMDGMGGPRGRKRAKIEEVIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MV70</accession>
    <name>A0A9P6MV70_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_010117</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000670">
        <property type="protein sequence ID" value="KAG0014993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MV70"/>
    <dbReference type="OrthoDB" id="687730at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000151">
        <property type="term" value="C:ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15067:SF7">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE DMA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15067">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RNF8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17123">
        <property type="entry name" value="zf-RING_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FHA" evidence="8">
        <location>
            <begin position="73"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="9">
        <location>
            <begin position="201"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="291"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="419"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="460"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="532"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="291"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="311"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="335"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="428"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="465"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="544"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="578"/>
            <end position="588"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0014993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="588" mass="62199" checksum="9A96399067CE480F" modified="2023-09-13" version="1">MSSPISSHAIQATPTATSAEAPVSASAAGTSATPANTSSTTPAPHIRIVPHLDAPRSLHFEVVDKDVPEGFVLKIGRFTDKQSLPNRVTFKSKVVSRGHAEIFTENGKFFIRDTKSSSGTFLNHARLSPPGVESKPTPLKDGDVIQLGVDYQGGTQEIYRCVKMRLELNRSWQQHSNPFRENTLKAIRSLTTADASCSTDCCICLFRIASFQSLFVAPCSHVYHYKCIRPMLVSNHPGFLCPLCRTFADLEDPVEIDDPIEENKPVQSSVAAAADHEVPEDNPIEQIVEAEPTSPTQPEQTSTSTDAVSAPTPTSAHAHTSQAPENAAMQLDTAGSGSDSEGSSEAQPVSAPSPSSSPSPVQQQSLTSATVPPMNIAGAGSPTPVDSTAQQSPSSAFFMAPSPPMFGSSLGVSPISFAATSTNSNSRQPSTSSQHQHSSSPTSHMGHMFQNFVRNITIPHRNRSRTNSNPATPTIASNTNSTGQPQISGSEVYGKTLVMTPPSIPLVNNRTGTGHSGSELGVVTEMDVEQSFMNDQPEGDGNESSSSSSGGRNSSRSSSQSRDAHHHLEESAGAALHNSHTITAEATV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVB6</accession>
    <name>A0A9P6MVB6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_010451</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CHEK2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000729">
        <property type="protein sequence ID" value="KAG0014413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044773">
        <property type="term" value="P:mitotic DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006624">
        <property type="entry name" value="Beta-propeller_rpt_TECPR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167">
        <property type="entry name" value="OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167:SF18">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00706">
        <property type="entry name" value="TECPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="1"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="FHA" evidence="5">
        <location>
            <begin position="236"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="120"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="340"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="683"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="816"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="957"/>
            <end position="1101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1114"/>
            <end position="1254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1280"/>
            <end position="1303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1328"/>
            <end position="1365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="120"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="137"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="342"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="706"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="739"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="895"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="957"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1040"/>
            <end position="1058"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1070"/>
            <end position="1088"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1147"/>
            <end position="1164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1165"/>
            <end position="1194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1195"/>
            <end position="1209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1219"/>
            <end position="1233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1280"/>
            <end position="1296"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0014413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1394" mass="153296" checksum="83A851096608F0BD" modified="2023-09-13" version="1" fragment="single">DNIVLFKDVSQQQYKTYIFTEFVDGITLHEYYRNCNYFSELDARHIFQQVCEAIQYLHGNNIVHRDIKSETSLGEGENGYSKPVDIWALGVMLFRMLVGSYPFGEVQDATSTAKVEAIPAENAAAIPENPTNQTETGKPETEPEEQRTERRYSVYDRDWQKMLNRNVPRSQEVRNLLVNMLKPDPSRRIKIDSVLKHDWIRMIDEEMQKFEAAARDKTVILANNSDLPEEQYSGSGREDKWGELTIAQNCVPDAPRRVDVYLGKDRAISSVHCLIIREGDTIFVANADPHNGTYVNSMKVENKRAVQLFDGDDLGIIVPPENREESSNYTLEPPAAKIRNLSISPPSSQSSSSSTSPSNRKRAIPPPNPELIWGTLHPVNANTERRDLVEPRISIGRGFGEDYWVEDDKRAYLSSTGRSGTTVNGIEVDTPEPYQLRHNDEICLVQNRSGAHHNDHNARALALSQSDQESDSTFQVSAAEDGTVVRLDKTFKTWYLVGSQNRVDFENDVIWIDLGHSWKCVSVASVSQIWGLGDNGNIYYGTSDQFVQLKSPITSGAGYDMPKFTQIAVGQDNIVLATDAHSGTVFRLKTHPASSHPPVWAALEGTGPGTAIHMMCCSLSSVEFIVGLSKEGQVFRRCNGNWIPIGGKIKFSCIDVGIDGYVMGVDRVGDLYACQLQNTMGVPRRVPSRNSQLNRSKDEDLDVPKSPQTPNIPNLPSTPRPQNVSKRPSASSRELFEMESSNRASSPGPSRLSQGDFAREYISNSGRSSPGRYTFGRTESQVSYATELGLDTAQLQRSDSLSKKLANRVTPLRIMASRENSSYRNPDGDSYFTSNPTPGLGPSYDASPSAGSPTSRKRNSTDSRGSSRLACSEALPSEDDRKHPFVKSASSLTSKESEGRWISREDVGNKQELPDPEEPLKLLQLQRPSIADENANATNDTTVAAVSAVVLTPNKESSNSLSIHRSQPQEPDNMGHLKSEWNESVDNMPKPPSQVLNNGYFGPRPGDQLGGSPPFFSTNSDYPLAQPSTPNPGAPYSVNRYPTSMSEPWQGVQRQNQAPGILTAYGSFPRNDRRDDQQPPESMSHDKVPGLASRPSDASDLSLKQQQEFLRLTRLHSNPSAAIDNSGGSPEKAGGAAHVDPDDIENSHSYNDTSISRHSSYKPDNSSGKESYSSSNNGPRGNNSSGPYGNNSNRPQVNHVNNPYDNNANGRRVSYNPYSSNNTLPNGTNNVNSTGKAELSDDMGPMNQQKTGPYGRSSIITTTVTFSGEAAGTNAGLIARRDPYSTSHTEDVHETPGRPSYSSSYLQQYVDTTLLPQPAADVRMSSSFGKQEIDGSAGDSSSLVLRQPRRQSKSQGGIQGEDLQGRWVGGATVSDSPIAQFDPEVHKFKCCLIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVI3</accession>
    <name>A0A9P6MVI3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">AP-1 complex subunit gamma</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">APL4</name>
        <name evidence="13" type="ORF">BGZ80_010688</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="9">Adaptor protein complex 1 (AP-1) is a heterotetramer composed of two large adaptins (gamma-type subunit APL4 and beta-type subunit APL2), a medium adaptin (mu-type subunit APM1) and a small adaptin (sigma-type subunit APS1). AP-1 interacts with clathrin.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the adaptor complexes large subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000771">
        <property type="protein sequence ID" value="KAG0014054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVI3"/>
    <dbReference type="OrthoDB" id="28053at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030121">
        <property type="term" value="C:AP-1 adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016482">
        <property type="term" value="P:cytosolic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000030">
        <property type="entry name" value="AP-1 complex subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050840">
        <property type="entry name" value="Adaptor_Complx_Large_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017107">
        <property type="entry name" value="AP1_complex_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008152">
        <property type="entry name" value="Clathrin_a/b/g-adaptin_app_Ig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013041">
        <property type="entry name" value="Clathrin_app_Ig-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008153">
        <property type="entry name" value="GAE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22780">
        <property type="entry name" value="ADAPTIN, ALPHA/GAMMA/EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02883">
        <property type="entry name" value="Alpha_adaptinC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037094">
        <property type="entry name" value="AP1_complex_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00809">
        <property type="entry name" value="Alpha_adaptinC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49348">
        <property type="entry name" value="Clathrin adaptor appendage domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50180">
        <property type="entry name" value="GAE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="6 10" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0813">Transport</keyword>
    <feature type="domain" description="GAE" evidence="12">
        <location>
            <begin position="746"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="722"/>
            <end position="748"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00062546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR037094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0014054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="867" mass="93795" checksum="37E043D1963C6D92" modified="2023-09-13" version="1">MVFYRLKDLIKAIRACKTHADERAVIQKESAFIRTSFKEENTELRHSNISKLLYIHMLGYPAHFGQIECLKLAASPLFSDKRLGYLGTMLLLDENQEVLTLLTNSLKNDLNHANMYIVGLALCTLGNIASAEMSRDLCSEVEKLLGSSNMYIRKKAALCAIRIIRKVPDLQENFIQRASSLLNDRNHGVLLSGITLITEMCLSSQETLLQFRKAVPVLVRHLKNLVSAGFSAEHDVTGVTDPFLQIKILRLLRILGKDDVESSEAMNDILAQVATNTESSKNVGNSILYETVLTIMETPSDNALRVLAINILGKFLSNRDNNIRYVALTTLNKSISLDVNAVQRHRNIILDCLRDADISIRRRALELSFSLINESNVRVLTRELLAFLEIADNEFKPSMTTKICLAAERFAPNKRWHIDTVLRVLKLAGNYVREEMLAAFIRLVTQTSELQGYTVQKLYTALREDISQESLTLAGVWVIGEYGDILVSGGSYEEEELAKEVSESDVIDLLESILAGPFANQVLREYIVTALMKLTSRFTSASSSERVKQMLAGFSTSIEVEIQQRAVEFTNLFQYDEIRPAVLERMPVMQIKETVIAGERLNSAASGNTGSQTSAPAGPSDQDLLLDLMGIGTSGGTTNAQISTGAPASSGNGPANNIDLLADLFGGSSVSSLPTASNPSAAVVSNLFAGIGSPAATSPPVSNAGANILDLLGGGMPAAAAPSTPAPAINRTASSNSNGSASAQSPAQKTFPVYSKNGLSIVFTPQRDSANPNVVNILATFNNDSGVSGGAINGVQFHAAVTKTQQLQMRPASSTEIAPGGNATQLLKIANPQKTPVRLRLKVVYTTVNHGAVTDLSEFAGFPDGAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVI4</accession>
    <name>A0A9P6MVI4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Emp24p/erv25p- protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ERP1_2</name>
        <name evidence="10" type="ORF">BGZ80_009912</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the EMP24/GP25L family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000637">
        <property type="protein sequence ID" value="KAG0015341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVI4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015720">
        <property type="entry name" value="Emp24-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009038">
        <property type="entry name" value="GOLD_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22811">
        <property type="entry name" value="TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01105">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01190">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50866">
        <property type="entry name" value="GOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040114766" evidence="8">
        <location>
            <begin position="25"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="GOLD" evidence="9">
        <location>
            <begin position="34"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0015341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="219" mass="25385" checksum="8225E7F28FF410E7" modified="2023-09-13" version="1">MTNNFTRWSICLLAMLSILPSVFGLYFYLEGSEQKCFTEELPKETMVTAHYSAEEWDEQTKTFTDNKDIMIEVIVDELPSGNRVYSQKLSRKGKFTFTSAESGEHGICLYTSTSGWFSSTKIRVNFDMEITDIMDNDSDTPDSALSDLALRIRELNHKVGDIRREQSYLRDHEMDFRDKSEATNGHTVIWTIVQLVVLAVTCAWQMRHLRSFFESRKMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVL7</accession>
    <name>A0A9P6MVL7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mitochondrial ribosomal protein subunit L20-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_010264</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000698">
        <property type="protein sequence ID" value="KAG0014716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVL7"/>
    <dbReference type="OrthoDB" id="6021263at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024388">
        <property type="entry name" value="Ribosomal_mL58"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28266">
        <property type="entry name" value="54S RIBOSOMAL PROTEIN L20, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28266:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12824">
        <property type="entry name" value="MRP-L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="65"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0014716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="187" mass="20947" checksum="6EEE606FCD9A7F85" modified="2023-09-13" version="1">MFKSSITQSAPAFARGYATNVTRTLFPRHYRLRHKVLSESDATPLKDGSLFIRRPTAGPTTSILSSVNPSPASVSSRAPGSATSTPLSHPDLPPALNANKAPRPEFAKLTPEQIAEMKALRLENPAKYTRSYLAKKYNVSELFVKIYVPASKEVQIARIKAQQRSFDKKGWKAQEIVIQRQKRRELW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVT0</accession>
    <name>A0A9P6MVT0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_009914</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000637">
        <property type="protein sequence ID" value="KAG0015343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVT0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0015343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="157" mass="17602" checksum="9255C4DA01D41991" modified="2023-09-13" version="1" fragment="single">DFRPETYTTKGYYAKGSIRTNSHTLQVLCFKLRELLSVKYKRLPDDSLSPRLTPTTHGTGDFLSEIRNVLGTKEDVANLWPGIDPQNIKTLTLDAGQAYVVGGYAYLPRIDEQERVPFLQRLTPYSLLLYNNTTGSDANTVFGATNNFKVASNYDSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MW17</accession>
    <name>A0A9P6MW17_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_009662</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000599">
        <property type="protein sequence ID" value="KAG0015742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MW17"/>
    <dbReference type="OrthoDB" id="2434237at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0015742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="279" mass="31344" checksum="95D3F4189AD639C8" modified="2023-09-13" version="1">MNHIEVKLDGLDRSLTTIAASLGSSTSFSEDPTDGPQSLPPLRDFLSEQIPALVKLKKLQQTADGISSTLSSLSLITDSSQPPAYRETGPPELVRIRNKIELVKGILVGIINTKPNGPLKPLPPDLASDDDDDIFIVWCIADDRPSYMRALYQIIEDLQVKETEQWRSYMSLNRLGKDASDSLYRKHIRAKINSAKRAISEYHQKTVESKVKLGMPDLPSDPSLLDVDVFKVICLQSNDFYTQYHRPAIPRYDKAIGALIIKLMGMEEEEKRRLLAPRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MW72</accession>
    <name>A0A9P6MW72_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box/LRR-repeat protein 15-like leucin rich repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_010068</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000662">
        <property type="protein sequence ID" value="KAG0015072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MW72"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057207">
        <property type="entry name" value="FBXL15_LRR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25372">
        <property type="entry name" value="DUF7885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box/LRR-repeat protein 15-like leucin rich repeat" evidence="2">
        <location>
            <begin position="77"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="251"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="388"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="476"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="287"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="297"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="390"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="410"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="494"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0015072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="562" mass="61793" checksum="5DF3CD43649AA7AD" modified="2023-09-13" version="1">MEDEEAHVIFSHLLINQSSSNGDDNDEDSEEEQDKEDSVKEEESDRESDASDEDADGEDGNEATNSSPTQHSSTVANTPSQITQEDKDGHQTRLVYLGLSQCRLLTHEALRAIGHLCSQHLRRLELSNCENIGDEGLIQLAQRCSRLRLLDLEDVGNLTDVSLRAFAMYLPKLERICLSYSENITDQGIIRMLRPASNPTTLSTATAMMINAETASLYCRKLVHLELDNCPLITDQLLLEFANVLEERAAASMERQKERERKREERRERIRQKKRAVSPQKQSGYGLEDKGEEHSPRASSDQTGVEQGQDTSAAESSSMASVAGASFASSRPVNIPNRFRHIPAIVGSSLTSYSSSPLQPRSVLASTLLSDEVVIKKTRPGTRIMVPARSASTSSTTSCTSLPPWNSGASSRRNNSSVTIVNGGRRANGVVVNKPIRPTIQVFDCRNITLEGVEAAQTQCSSLTIRSYYSWTHPETSAPTTSAAFGGSSAIEGVDGDEGDEDTDTEHNMNTSQTSLHHLQLQQQHLQQYLQHRSRASDLLRRARLGLIGRTGGTQDAQCTIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWK3</accession>
    <name>A0A9P6MWK3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cyclin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_010100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cyclin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000669">
        <property type="protein sequence ID" value="KAG0015002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWK3"/>
    <dbReference type="OrthoDB" id="10264655at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20532">
        <property type="entry name" value="CYCLIN_CCNL_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20533">
        <property type="entry name" value="CYCLIN_CCNL_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043198">
        <property type="entry name" value="Cyclin/Ssn8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10026">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036580">
        <property type="entry name" value="Cyclin_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0195">Cyclin</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-like" evidence="3">
        <location>
            <begin position="42"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin-like" evidence="3">
        <location>
            <begin position="158"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="279"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="279"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0015002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="317" mass="35731" checksum="5F224D6379A0E47A" modified="2023-09-13" version="1">MHQNKLSLQNALLTLEQLQRTPSREDGITEEQEDDLRQFGCHLIQTAGILLKLPQVAMATAQILFQRFFYQASLRKFAIRDISIGSIFLAAKVEECPVRLTDLANVIDHLQKKFRRSPLDPLVPFGQEFYDLKNAVVIAEMQILKKLGFNVHVQLPYAIMVNYLKVLELTDHPTIPQRAWSFLNDGLRTSIYICYQPPTIACSVIWLAAREAEVPLPTNPAWWEVLDSNLEDIENIAGHIKSLYYKTLPIPDLPLTINEVEPYLQKQKSIALALADAESRTGKKKGQDGEEAEQAPVQGGDSGSVVPPKNTRVSRFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWK5</accession>
    <name>A0A9P6MWK5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Deoxycytidyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">REV1_2</name>
        <name evidence="3" type="ORF">BGZ80_009875</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000630">
        <property type="protein sequence ID" value="KAG0015429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWK5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017125">
        <property type="term" value="F:deoxycytidyl transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070987">
        <property type="term" value="P:error-free translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042276">
        <property type="term" value="P:error-prone translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17719">
        <property type="entry name" value="BRCT_Rev1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10190:FF:000011">
        <property type="entry name" value="DNA repair protein REV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45990">
        <property type="entry name" value="DNA REPAIR PROTEIN REV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45990:SF1">
        <property type="entry name" value="DNA REPAIR PROTEIN REV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16589">
        <property type="entry name" value="BRCT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="BRCT" evidence="2">
        <location>
            <begin position="43"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0015429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="212" mass="24173" checksum="616ABF923732AC05" modified="2023-09-13" version="1" fragment="single">MEREREDDPYEAIQFGDFGTYIRHKKQKLQLQQEEIAALAAPNTAQIFEGIVVYVNGYTDPPIHELKNMIVQRGGEFRQYLSKNSTTHIIASNLTQAKMREFRNYKVAKPEWITESVKANRLLQWHKFSTLNVPTSFSKFGEASLTQSLSMTPSSPSYHTNSGSSADPKHKDRDSVPLELLEYTHVDLPDRRNKDSHMLGKTARACVDGDVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWL8</accession>
    <name>A0A9P6MWL8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">LIM zinc-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_009187</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000529">
        <property type="protein sequence ID" value="KAG0016492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWL8"/>
    <dbReference type="OrthoDB" id="1112565at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08368">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.110.10">
        <property type="entry name" value="Cysteine Rich Protein"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001781">
        <property type="entry name" value="Znf_LIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24205">
        <property type="entry name" value="FOUR AND A HALF LIM DOMAINS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24205:SF16">
        <property type="entry name" value="GH01042P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00412">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00132">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00478">
        <property type="entry name" value="LIM_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50023">
        <property type="entry name" value="LIM_DOMAIN_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0440">LIM domain</keyword>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="LIM zinc-binding" evidence="7">
        <location>
            <begin position="1033"/>
            <end position="1097"/>
        </location>
    </feature>
    <feature type="domain" description="LIM zinc-binding" evidence="7">
        <location>
            <begin position="1106"/>
            <end position="1165"/>
        </location>
    </feature>
    <feature type="domain" description="LIM zinc-binding" evidence="7">
        <location>
            <begin position="1166"/>
            <end position="1229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="102"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="167"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="213"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="268"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="319"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="401"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="468"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="648"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="697"/>
            <end position="1030"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="115"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="140"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="238"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="290"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="330"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="362"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="423"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="470"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="520"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="589"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="711"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="735"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="783"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="813"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="876"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="911"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="927"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="953"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="974"/>
            <end position="995"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1016"/>
            <end position="1027"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0016492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1251" mass="140496" checksum="1B35E510BACA7C54" modified="2023-09-13" version="1">MSSFTVQLPDPRLSKILPVIHCSDCGQDVEYRKLSNHNCIYAPAMPIIPLSLSTQPTSPSDSITTTDRYSIQKKIPSVTKSTTTNTSPLSLIRSASQRSRPALPYLEKYSKRKSTSAPAILSQTTNLGRNSLDSNVNRNSQQGLSQQQQKRALSPIIAAALSDSDQDLVTPRASIDERSSPLTSGRFSPDIDQNKHMMETICNYPVRPARASQQLPLVPKKSAARTSGIAPRRGLEISTDNSKQTLLTTGQSSDARIIFELDQEREREWEKSNRSTPPAIASSAANGLTRPNSFESISSSSSWGTKCSLLERSGSALAMNSLRPERPKRQSSPCQSEQSRYSNELLSAQRQKKEPRQILSPSTTASGESSPRSSTSTYTTHSPPLSPLDELVELEIVNEPQEIEYRPPTPKSSSPSPIPPKDSLSEELKEDSSETQSESDVDVDQFETLMENILLEIKIKAMPALKCDSSRTTRTQVVETVNPARKRVTSPSPDPIPAQTTVVRRADNDRNYPSILSKSTEPKVLCRADDTRKRPQSPTPVLTKTTKATEETRGSLTPAQPRSTRRSEDIRKSPSPVPPQPRAVRQLEDIQNSTLLQTTTVRQTGVTSPTPAPRVKATHRIDIVESAPLSPELRPNVTREAHRTDLVDSTPLSPRLRPNATRETEVTSCTKTVKSAPLSPPLQPKVTRETYRSNVVESTPLSSRLRPNVARRTEATNRTEAVKSAPLSPPLRAKVPRETRRTEGVESAPLSPLRPRASRETEVTCRTKALKSAPLSPPLHPKVSRELRRNEVVESTPSSPPHCPRVTRETEAIKSSPTQFQTRRLRQDENLQRSTTPPPTQFQTRRLRQDEDLQRSTTPPPLQPRAARRSVETRDSPSQAPVQSKATRRTSPLPLTNKLKQSFRQSEDVRSPPPPPAPEPQPMISRRSNETRNQRSVKEDKERVEKTSGSVIRSDKTETSEKSKKTVKVTRFNHVHEQEREQEQSDHSFEREHSRGPTTRSEPIGKVNKELDRSPTSRSVARNQSTKGRGGIERCADCKNDIQPSELADSIKMAYGSYHSECMKCSQCRVFIPSSLDAHEFEGHLLCENDYAKMLEKEVLRPQRRRICAGCETPIESTDQVVYALGKPWHEHHLFCYHCLKPIREAHMEKSGRVYCVRDYNELFLPKCKACGLKIESNIISAKDNKLTGKWHADCFRCRTCRREFPDMKFYVFKDQPYCKRHYHRLNNSMCMRCDEPIEGHCAQTMEVRQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWP9</accession>
    <name>A0A9P6MWP9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_010017</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000654">
        <property type="protein sequence ID" value="KAG0015158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWP9"/>
    <dbReference type="OrthoDB" id="342454at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46620">
        <property type="entry name" value="J DOMAIN-CONTAINING PROTEIN SPF31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46620:SF1">
        <property type="entry name" value="J DOMAIN-CONTAINING PROTEIN SPF31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="33"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="226"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0015158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="236" mass="27030" checksum="11B1999BC332B606" modified="2023-09-13" version="1">MADIDIDRILEVEASAVQKDAEVERIMSCFKLDPYDILELEVGCVEKDIKMAYRKKSLMIHPDKINHPKARDAFDLLKKAETDLMDPAKRSFLISIIDEAKFEVKKAQPLAMAPTDPFFTSPVYKTLVKQKTKDLLIEVELRKRKLIKKEMEAEGEVARKQDEVISERKRKQEAQKVWEDSRDDRVQGWRNFQAGKTSGGKIKKKKPSTFRPPKAVAEDATPYSKRPTTSSASEGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWQ9</accession>
    <name>A0A9P6MWQ9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ribosome biogenesis protein brx1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">BRX1</name>
        <name evidence="7" type="ORF">BGZ80_009067</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the BRX1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000516">
        <property type="protein sequence ID" value="KAG0016632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWQ9"/>
    <dbReference type="OrthoDB" id="1638493at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007109">
        <property type="entry name" value="Brix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026532">
        <property type="entry name" value="BRX1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13634">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN BRIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13634:SF0">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN BRX1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04427">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00879">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50833">
        <property type="entry name" value="BRIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Brix" evidence="6">
        <location>
            <begin position="33"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="272"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0016632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="292" mass="33706" checksum="808F744244D6C27E" modified="2023-09-13" version="1">MATVFKQQKTKRDKAEGIVANDAEEKAIFKNKQRVLLLSSRGITFRHRHLLSDLGNLLPHTKKDAKLDSKSKLHIINELADLNNCNNCIFFEVRKRQDLYMWVSKTPNGPSMKFHIQNIHTMEELKMTGNCLKGSRHILSFDKNFESSPHWMLMKELFTQVFGIPKTSRRIKPFIDHVISFSIVDNRVWFRNYQITQKPVEHRSATDTTDLTLVEIGPRFVMNPIRTFDGSFGGQTAFENPEFVSPNVARAKVRNAKAGRYKDRMEALAKRDQKMKDAVLPDDPLSEKNVFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MX14</accession>
    <name>A0A9P6MX14_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="8">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">UCHL3</name>
        <name evidence="11" type="ORF">BGZ80_009448</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7 8">Belongs to the peptidase C12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="8"/>
    <dbReference type="EMBL" id="JAAAID010000568">
        <property type="protein sequence ID" value="KAG0016071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MX14"/>
    <dbReference type="OrthoDB" id="427186at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09616">
        <property type="entry name" value="Peptidase_C12_UCH_L1_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.532.10:FF:000006">
        <property type="entry name" value="Ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.532.10">
        <property type="entry name" value="Peptidase C12, ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001578">
        <property type="entry name" value="Peptidase_C12_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036959">
        <property type="entry name" value="Peptidase_C12_UCH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057254">
        <property type="entry name" value="UCH_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10589">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10589:SF17">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01088">
        <property type="entry name" value="Peptidase_C12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00707">
        <property type="entry name" value="UBCTHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00140">
        <property type="entry name" value="UCH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52048">
        <property type="entry name" value="UCH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7 8" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7 8" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4 7 8" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UCH catalytic" evidence="10">
        <location>
            <begin position="13"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="151"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="151"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="7">
        <location>
            <position position="103"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="180"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="7">
        <location>
            <position position="97"/>
        </location>
    </feature>
    <feature type="site" description="Important for enzyme activity" evidence="7">
        <location>
            <position position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0016071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="246" mass="27494" checksum="1C73C6878B6A2F6D" modified="2023-09-13" version="1">MSTPATQPSKKIRWLPLESNPEVLDKYVRDLGVPAPWRYADVMGLDEELLAFVPQPVHALILLFPITPKYEEYCKEEQQKIDQNGQIVSSKIVFYPQTISNACGTMGVIHSIANNWAHGGSLKLKEDGIMEKFLKKTVDLSPAERAKALEEDKSLASVHESHASTGQTETPNLADEVNLHFVCLVERDGHLYELDGNKPYPINHGTTSNETFLLDAINVAKEFVKRDPDNLNFSVIAATTAEEEDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MX41</accession>
    <name>A0A9P6MX41_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">glutathione transferase</fullName>
            <ecNumber evidence="1">2.5.1.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_009286</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>RX + glutathione = an S-substituted glutathione + a halide anion + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16437"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16042"/>
            <dbReference type="ChEBI" id="CHEBI:17792"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:90779"/>
            <dbReference type="EC" id="2.5.1.18"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.18" evidence="1"/>
    <dbReference type="EMBL" id="JAAAID010000540">
        <property type="protein sequence ID" value="KAG0016354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MX41"/>
    <dbReference type="OrthoDB" id="414243at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050213">
        <property type="entry name" value="GST_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571:SF224">
        <property type="entry name" value="HEMATOPOIETIC PROSTAGLANDIN D SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14497">
        <property type="entry name" value="GST_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="4">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="5">
        <location>
            <begin position="98"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00047960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0016354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="250" mass="28568" checksum="1E57C9F4579BA4F4" modified="2023-09-13" version="1">MKTFDLDLEGNSKLVASDNLKYTVGYFAMHLGGTSSRGILAYADADWTPVYQVEKSEMPFEFIPVLTVIHPDGKELVLAENVAIDIFLAKQFGLHGQNAWEEALINSFYSSSNTMFFQEVMNNFFWESSGKSDEEKKEYLDKFLNEQLQKWARTHEAHLENNRLNGHYVGNRTTLADIRTTTLLDATEKIVGKERIATIVNETRTPGIIKVRKNVESKPSYQSWITSEEYKKLDVKTASFIKSQHPELVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXH6</accession>
    <name>A0A9P6MXH6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Aldehyde dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ALDH3B2_3</name>
        <name evidence="9" type="ORF">BGZ80_009120</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4 7">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000521">
        <property type="protein sequence ID" value="KAG0016577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXH6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006081">
        <property type="term" value="P:aldehyde metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000025">
        <property type="entry name" value="Aldehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000004">
        <property type="entry name" value="Aldehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012394">
        <property type="entry name" value="Aldehyde_DH_NAD(P)"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43570">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43570:SF16">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE TYPE III, ISOFORM Q"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036492">
        <property type="entry name" value="ALDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2 4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="8">
        <location>
            <begin position="16"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 6">
        <location>
            <position position="223"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR036492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR036492-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0016577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="493" mass="54295" checksum="1C70452D9F64259F" modified="2023-09-13" version="1">MAQNDIPIVEYTPLSDIPTILQDVRATFKSGLTKSLSYRKEQLKGLHNMIAENEDLFREASFLDLRKPPQELFLGETGIIKHECVEAIKNLDRWASPEKVKVSLINKFDDIHIRKDPVGVVLIIGTWNYPVNLLLIPAIGAIAAGNTVILKPSEVSPHVAKLVTELLPKYLDQRSYRIVNGAVPHTSALLDLKFDHIFYTGSGNVGKIIMAAAAKQLTPVTLELGGKSPAFVAKDGNINTIARRLAIGKFFNSGQTCIAPDYVIVERGVENELVKEMKKTLLEFYGAAPQTSPSYGRIVSKGHFHRLVQGLKNTQGEVVIGGDSQEDDLFIAPTLVLNVKPDDSLMQDEIFGPILPIMVVDSMEDGVDYVNSKDQPLALYIFSGNKKLVNHILDNTRSGSAVVNETMVQFTITTLPFGGTGPSGIGSYHGKKSFDTFSHERSTVIKSLGMERFNTVRYPPYSEKKIGWLDWLLYSKVKYAPNAANPGASKANL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXJ6</accession>
    <name>A0A9P6MXJ6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_009492</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000574">
        <property type="protein sequence ID" value="KAG0016016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXJ6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="211"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0016016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="222" mass="25074" checksum="77A0CF6EDF07001C" modified="2023-09-13" version="1" fragment="single">MATNTGKAVTIDSKPSYCDVASNRRRNVEKPATLSTQSQPRQSSGANTSNTRTWQQAHAENQRTINELRNQLEQQKRLWEMQRQEIRDQFAKLDDKLDFFLHQQKFYSPTVRDDDDSMDEEEEDDVMEDAPTRTPSLNSIPPGSLATPSDHITPQDLSNTISQSNATLEFNTTATIIKRPHYSSDAPSEDATASSAKSKIDPEQATSHLQHQLDESRKQIAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MY02</accession>
    <name>A0A9P6MY02_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008374</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000451">
        <property type="protein sequence ID" value="KAG0017354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MY02"/>
    <dbReference type="OrthoDB" id="2405020at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="6"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0017354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="572" mass="64706" checksum="E2F6E68CFD3E16E2" modified="2023-09-13" version="1">MPTFIHTSIFDVPEELFSMIIDLLSPHDITKLMATCKILYYKLEPFLWRHVTIGDHLPEKESLLRNRKHIQTLDVGGKAKDIFDILGSHLPPEGPVSTLHPSIAAYIALPATINLRKLLIPGSVFFCSRSVRKDTRTISHIIPVIRNSPNLMQLHIHTDLIKSYRDIILDTISNKLPLLRILSVGGDSVSLKSGLEFLLTCFQHPRLEDLRCDFSFASTGNSKTFGRTLDSALSPLAPKRRKKSLSSTAPSGSIITAIKLPHFNEKMASIVVRVLYIVRDFCPHLERFEIPNLHFDYDAERDCPSEGWFNHLQHITYPNSYYRVPIYGPSPNFVNSLLEGCSKGAGIKTLDLPDLRDGENASKEANLLGTLAKFYSRTLEEINIDHYVSLTSRDIQDILKTSEKLTKFWIPTTTLVGTLSGDWVCLNLKVLSLVFDASTEQGNGQGGKQSQVLAATHVFEQIGRLTKLETLRLGWTGVTCSCFSNVGPEHPSRLHPSVELETLAGLRNLRHFYMFTDCWQHVGQAEVEFMHGHWPCLEKITVQRLGPGYPIERPHWEWLKEQRPQLRLDGVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYM3</accession>
    <name>A0A9P6MYM3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ion transport domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_006706</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000332">
        <property type="protein sequence ID" value="KAG0018812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005216">
        <property type="term" value="F:monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098703">
        <property type="term" value="P:calcium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024862">
        <property type="entry name" value="TRPV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036930">
        <property type="entry name" value="WGR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10582:SF2">
        <property type="entry name" value="INACTIVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10582">
        <property type="entry name" value="TRANSIENT RECEPTOR POTENTIAL ION CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69322">
        <property type="entry name" value="Tricorn protease domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142921">
        <property type="entry name" value="WGR domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="1137"/>
            <end position="1156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="1176"/>
            <end position="1194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="1227"/>
            <end position="1244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="1256"/>
            <end position="1280"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="8">
        <location>
            <begin position="1141"/>
            <end position="1291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="588"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="849"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1050"/>
            <end position="1074"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1401"/>
            <end position="1477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1502"/>
            <end position="1531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="849"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1402"/>
            <end position="1430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1432"/>
            <end position="1444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1507"/>
            <end position="1516"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0018812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1699" mass="191259" checksum="C7B3C63DA91B2C87" modified="2023-09-13" version="1">MIKPNSKASLDASHDDKPPLISRNCPGFTFDVMFENQVAGRYYIVWKLRLQEKVSIPWDLHAQATVSYEDEPAERSGSLDVVIPKTRIENLELNDWQDIVIQEQLIIHANSGSARVNMTLRNNGELETKDNEDESRTDPIFEVLSVEIHPYSRVHVDDNNLNTAPGNPFKSIDVGITYNTPISCISAATEVEQIAVLCVENNMIHVSTWDYSKIQTQLGDDKHSLFDGKPKVVKDIPCEDGISKLPLGISLSPDGKQLAIFQEPEIGDWGAGAAVKEATFKFQLISLDNPVSKSGLANTEVYVIPMDGHTSQSNVSIQESKISVLQSFVGFAKFLPSIVDSEHSAQPKDSVKNSDANNCQPLFAACDGIYLDVFDCSQTEWRHLHSITLADLPPHLSRRITCRMMMESIGPSTFLWLEDQGQTCSTWSITNGANINHLSSEGDVNFTDRVYRSNLKMAISPDESIIALAGVDGSIRTFFAKSGIEINPANHVRFINSKIEYLGFLGRNDRMLVIVHNNTNHKLESRILDPLDFRFRIKYNPVPIPTAGTTLLLAARNASSTSNGQGMVCAADGKFLRFYSIQEIPLDPPVDPSAKPSNKHADKKLGEISATVDSENREYGDAGFQENGELIYSLHISAEAKPLENGDGKDYLALHVSVLQKTKSSDFDTKVLFDFVPEPWLRCPTSVQNKPDQLLTAYFLSCKKRFVIIGYQSIQIWALPSKKYPMVRLLAFWSKPCDFKSLLKEPLSYSEIYDKFQTIDDAWVFETHSDVTQLTVRLLNGTDEDVILPGLSRSHHGALDCYRSIYLLAASYFFASENEAYGAHASALVRFAVRYINRITTLKDILGDAKPNADEHESGDSKLKMGSPTPNGHEVKLAEIKESEGVDMLRLLIYNRGFQHTSNPFTKAILLTGDWIPREGSAWNPIQQAIEVEDHEIVNDLVNSCIGNAKTRHPAYLTPAIEVLDKLKTRYPSLTSKIFSEASYIKVKNKAYISTNAIVAKPPYQFWRSKSTHWSKYDNPVFCIQTQLPFQAIKPILLINRLLESITQPERTKSFPENQGESNTPGSKKTQQSLHTSSERCYDIYVVPFSKLSTYSGSGKENLSKFTEIAGTSLLDNPAMVATLRFKWYKFGMGPHLIWWISFALLAVYINVMFELKVFQPLGTAIHIILNIARRIIWFMAVFAITLIAFTHAFMHITHTRKNKCLDLTGEEQSQCEALESKYPKNFTALFSTFFFIAGIYDPLSNDLDPNSDTGYSFRIMLSLFIFFTVILLMNVLIAIMNDGYSESRDEGQLTWLKQWSEVIVDAELFMMRRSTRQNKYFFPDYIYYAANPQDVEDYERKEAAKRLLEYQTSDVIMRSVTKDKSKKKIMSVHQDVKYVLENQLKIERLMKTLHSISDLNSGHRRDGVFGTPHQHETAAQDHSATKADHITSASTAEQPTTEHPITHEPGASKGASSVQDLDNVSKPAVPKGGSWFQRKIRQTEAAAREIKNAASNAINDRVGQISKHNTPTHVTNVAHIEDETNEDVEDVEETVKETEVKGGEAFEPAMPTHVATIDKPSVDEFCPLRKTSQVYCDGDIYSAVLTDILRNVTCVIQLLYCDEARAYYIYYRYGESDCHLDGILMDSASAKVAFNVTYKDIFGVEWSERETAYSEHWKYEATSFSESCPSHLNKQKRCDAVTVIKRHGFCENDDLFAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZE6</accession>
    <name>A0A9P6MZE6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ornithine decarboxylase</fullName>
            <ecNumber evidence="6">4.1.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BGZ80_006605</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-ornithine + H(+) = putrescine + CO2</text>
            <dbReference type="Rhea" id="RHEA:22964"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="ChEBI" id="CHEBI:326268"/>
            <dbReference type="EC" id="4.1.1.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Amine and polyamine biosynthesis; putrescine biosynthesis via L-ornithine pathway; putrescine from L-ornithine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer. Only the dimer is catalytically active, as the active sites are constructed of residues from both monomers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the Orn/Lys/Arg decarboxylase class-II family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.17" evidence="6"/>
    <dbReference type="EMBL" id="JAAAID010000327">
        <property type="protein sequence ID" value="KAG0018878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZE6"/>
    <dbReference type="OrthoDB" id="5034579at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004586">
        <property type="term" value="F:ornithine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033387">
        <property type="term" value="P:putrescine biosynthetic process from arginine, via ornithine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00622">
        <property type="entry name" value="PLPDE_III_ODC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.10:FF:000005">
        <property type="entry name" value="Ornithine decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="entry name" value="Alanine racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.10">
        <property type="entry name" value="Lyase, Ornithine Decarboxylase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009006">
        <property type="entry name" value="Ala_racemase/Decarboxylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022643">
        <property type="entry name" value="De-COase2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022644">
        <property type="entry name" value="De-COase2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022653">
        <property type="entry name" value="De-COase2_pyr-phos_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000183">
        <property type="entry name" value="Orn/DAP/Arg_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002433">
        <property type="entry name" value="Orn_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11482">
        <property type="entry name" value="ARGININE/DIAMINOPIMELATE/ORNITHINE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11482:SF6">
        <property type="entry name" value="ORNITHINE DECARBOXYLASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02784">
        <property type="entry name" value="Orn_Arg_deC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00278">
        <property type="entry name" value="Orn_DAP_Arg_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01179">
        <property type="entry name" value="ODADCRBXLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01182">
        <property type="entry name" value="ORNDCRBXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50621">
        <property type="entry name" value="Alanine racemase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="PLP-binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00878">
        <property type="entry name" value="ODR_DC_2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="3 9" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orn/DAP/Arg decarboxylase 2 C-terminal" evidence="11">
        <location>
            <begin position="75"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="domain" description="Orn/DAP/Arg decarboxylase 2 N-terminal" evidence="12">
        <location>
            <begin position="80"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="9">
        <location>
            <position position="401"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="9">
        <location>
            <position position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00034115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00046672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR600183-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0018878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="459" mass="51122" checksum="488276572E2174A8" modified="2023-09-13" version="1">MIDISLQQDQFEVVPTLVQPTLVEVLKMRAKAQMAGLQSSKSLPQVHTLPIADMLAARLASFDPESEDAEAENAFYVADLGEVYRQHLRWKTLLPRIEPFFAMKCNPDPMVMRLLASLGAGFDCASKNEIQSVLDLGVDPSRIIYANPCKQNSFVKYAYNNNVRMMTFDNAEELYKIKRFHPEAQLVLRILTDDSKSLCKLGLKFGAPLDTTASLLATAQGLGLDVIGISFHVGSGCFDANAFGEAVIRARRVFDQAKDYGFDFKFLDVGGGFPSAHVTEGITFEKVASILGSTVDAHFGPEVRVIAEPGRYYVGSAFTLATQVIARRTIQHDADQALDNARNENPSHMYYINDGMYGSFNCIMFDHQVCEPHVLLRDGEFAYQQELMDRRSLASVWGPTCDSIDCITSKASLPLMESGDWLYFENMGAYTITAASQFNGFKKSEILYTTTEQEVTFHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZX7</accession>
    <name>A0A9P6MZX7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Proteasome maturation factor UMP1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_005661</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the POMP/UMP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000279">
        <property type="protein sequence ID" value="KAG0019530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZX7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043248">
        <property type="term" value="P:proteasome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008012">
        <property type="entry name" value="Ump1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12828:SF3">
        <property type="entry name" value="PROTEASOME MATURATION PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12828">
        <property type="entry name" value="PROTEASOME MATURATION PROTEIN UMP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05348">
        <property type="entry name" value="UMP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00043974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0019530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="144" mass="16219" checksum="95DBCC317C705678" modified="2023-09-13" version="1">MSLRLAPSSKPSAAGSASVLDTSNSYGLHDTMRFGMKQIASEITMKHPLENRLTEWEDTQEELKMNLARNLYGMHAPIKMAMERSLVIKARGPSMLPHRSNLGLDILMGKDETIDFEDFLNVPEMSTDFVDPHTVMERQIGLRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N000</accession>
    <name>A0A9P6N000_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_004724</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000238">
        <property type="protein sequence ID" value="KAG0020134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N000"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43119">
        <property type="entry name" value="ABC TRANSPORT PROTEIN ATP-BINDING COMPONENT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43119:SF1">
        <property type="entry name" value="ABC TRANSPORTER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="15"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="212"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0020134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="242" mass="26852" checksum="300B6DC1139A87D8" modified="2023-09-13" version="1">MTNPHSSSSSSHILFRAKGIGKKREDGTWLFRNVDLEVKNGVLTVTGPSGVGKSTLLKCINQTTPMDEGQVWLNNKTPDQLGIPTWRSRIMYIPQRTATMEGTPTDFLEVVRKFGTHKKKDTYDDPVQIALDWGIRPELWHSKWSMLSGGEMQRISLAIGCSFHPDILLLDEPTSALDEESCDKVEKTLKELNCIWVTHNPQQAERVSSAGTFRMRGGDNSSPSSLSGVVVDENGHTSGRAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0R5</accession>
    <name>A0A9P6N0R5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Histone deacetylase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_005771</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the histone deacetylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000284">
        <property type="protein sequence ID" value="KAG0019464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0R5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004407">
        <property type="term" value="F:histone deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0040029">
        <property type="term" value="P:epigenetic regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10001">
        <property type="entry name" value="HDAC_classII_APAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.20">
        <property type="entry name" value="Histone deacetylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000286">
        <property type="entry name" value="HDACs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023801">
        <property type="entry name" value="His_deacetylse_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037138">
        <property type="entry name" value="His_deacetylse_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625:SF17">
        <property type="entry name" value="HISTONE DEACETYLASE 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625">
        <property type="entry name" value="HISTONE DEACETYLASE HDAC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00850">
        <property type="entry name" value="Hist_deacetyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01270">
        <property type="entry name" value="HDASUPER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Histone deacetylase" evidence="6">
        <location>
            <begin position="33"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0019464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="379" mass="42070" checksum="A2D852E43E8A0359" modified="2023-09-13" version="1">MSHPLMKVFTSTLCTTLHTPQYEFLSGAQTHYYESPERLEAILQYLTSNPDSFEIMEHVEDFGYEPIKRVHKQDFLEYLKTAYEEWIKEGGHPNGVLPATIPHFKLARLGKLRPSNILAKSGEFCFDLSAVITKDTFKAAWNAAQVTLTATKDLVRISDEFEKSVAAGTVSRENPPGLYALVRPPGHHAQSDVCGGYCFMNNVAIATQWLIDQPDLKGKDGGPKKIAILDIDFHHGNGTQEIFYTVSNPLYTSLHSNEDYPYFSGSDLEKGEGEGLGFNINIPLPHTTTDDDYVETLEKLIKDHVIPYQADYIIVSLGVDTFKDDPIAGFLVTSEGYPRIGNAIRKIGLPTLFVQEGGYCIEKLGINVGGILKGYLGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1A8</accession>
    <name>A0A9P6N1A8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cyclin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004163</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000215">
        <property type="protein sequence ID" value="KAG0020462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1A8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="249"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="438"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="648"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="250"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="276"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="445"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="649"/>
            <end position="670"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0020462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="793" mass="88227" checksum="C150608CF250926C" modified="2023-09-13" version="1">MTASYHDPLRVIHTGPRISKPPHPRRQNSGHQPQHQSATSNHRNEDRQHYFHHKSHDPFMHNDRSLSSEEQTTPYEQQQHLNEQYDQQEHCVPSPTRLRSLSPRIQSSPRSSTRPPTIFAQLKAKLEAPKRPTITTTPLPQPAHSGKSLNRAPVSPDIIETDLTSPSSPAHDTRRYYSSGNCGHDNAWTTSPSTLFGIPCSPASQRAYSNHNLDIEESFLRLQLEDSGKIEHRTIAFATHLTISRWEPTDASASAAADQNSPESKTASPPSSSGESIEKSRSDRLSSRNPRDSESHPSSPKQQPQPQPQPQQQQQQQRNDPVYAARLVSLANYIRHILSLCSGNSTTNSQIALVQQQQQQQQQQLLRQQKLQACRPTSFSCTQQARNNSGTRIQDAASLSLPSPLSAGPGPIKPSAAMSMRKHRYSSEYYDYHARRQVHQQSRQTLERQDSLGEPMHRLPSPISPTFLAGRRLSQQQAESIATSISPLLRVPFPNLTLTLALIFVDRLKAKFPDAKGEPGCSLRLFLVAYIIAAKYRCSVELAALMRRYNTCVAMCEAEDLDESYDSNNSASIMERLARANSTAPITPVTPNNIPNRSAQTMREHYRDEAARLEQILWDMRSYAELIFSNQEWVRLLCLGSFFRPPPTTQSASSATTAAAASARTSPTQPMDRSIHSATSPEKLEPKPLPIQSIPSTRLAGVESANTLSCDTKIKSMTNLNSAQITATTNVTATATTTTTTTKTSTATPTSILQVEDLNRMETEFLTFLGFDLTAKSQDLDTCWNLLIGNKEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1C2</accession>
    <name>A0A9P6N1C2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_004102</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000213">
        <property type="protein sequence ID" value="KAG0020499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1C2"/>
    <dbReference type="OrthoDB" id="5570013at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0020499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="382" mass="40739" checksum="BA4597B874EBE3BB" modified="2023-09-13" version="1">MFASLVGLVHQPSIAVRFPNDDSSFNPKEFPSITFVAKGKVQGKIRLIHGTEDDSGQAIITTRIWVTKESDKNEVAIRTSFDNKTHTFTLEGPNRFGSFNIYHETSILIPSSLGYMGNLIIEAPNTSFSAEKLDTLSWNIVKCDLSNSTIALQSLHADSIDIRTSNSSVSGLFEAGHIDINTSNGPISAKLIVQRPLDGGQSSVTTKTSNASITLHVDASSASTGLRMGNSTKNSKIVVGTLLGPSSQSSSINTTTANGKIEFNLDASRSGQALEVSNVTANGSIASSIMVPQYQPFKGYAKSSNGSITMNLTEDFSGRFDLSTSNSNTVVEGNNLQFDEDKKTCKRGSHGKGSGDVNIVTSNSSIGLRFYPAGKSLGTDKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1P0</accession>
    <name>A0A9P6N1P0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Vacuolar import and degradation protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003956</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GID4/VID24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000208">
        <property type="protein sequence ID" value="KAG0020585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1P0"/>
    <dbReference type="OrthoDB" id="62at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034657">
        <property type="term" value="C:GID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045721">
        <property type="term" value="P:negative regulation of gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007039">
        <property type="term" value="P:protein catabolic process in the vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018618">
        <property type="entry name" value="GID4/10-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14534:SF3">
        <property type="entry name" value="GID COMPLEX SUBUNIT 4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14534">
        <property type="entry name" value="VACUOLAR IMPORT AND DEGRADATION PROTEIN 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09783">
        <property type="entry name" value="Vac_ImportDeg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00061469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0020585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="256" mass="29075" checksum="815C4FA945E2B3E6" modified="2023-09-13" version="1">MPVFTQICSADPATETTVTLATCTCACLTEGDMIIDSAYDTNSNIRTSLFIRIDGVIHWSNCALYLNATNSNFSLTGDNAPKNAMAMALLKQQQQQKVIGGLAVLRKPPVSSLPRRNDPFAPVRLSPTRTSHLYAGSRFRGKQKSGTVSYDVMVDIKMRFKPFEPMIDTFASEKFKYDFKDKDVIFMRWKEHFLVPDHRVEGINGASFAGFYYICYNKSTGEIDGYYFHRLSEKFQKLMLTHVEDQPLSFGSYEFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1T5</accession>
    <name>A0A9P6N1T5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">uracil phosphoribosyltransferase</fullName>
            <ecNumber evidence="4">2.4.2.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">FUR1</name>
        <name evidence="11" type="ORF">BGZ80_003871</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Pyrimidine metabolism; UMP biosynthesis via salvage pathway; UMP from uracil: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UPRTase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.9" evidence="4"/>
    <dbReference type="EMBL" id="JAAAID010000205">
        <property type="protein sequence ID" value="KAG0020645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1T5"/>
    <dbReference type="OrthoDB" id="106623at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004845">
        <property type="term" value="F:uracil phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008655">
        <property type="term" value="P:pyrimidine-containing compound salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2020:FF:000023">
        <property type="entry name" value="Probable uracil phosphoribosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001097">
        <property type="entry name" value="PRK00129.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14681">
        <property type="entry name" value="UPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="6 11" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphoribosyltransferase" evidence="10">
        <location>
            <begin position="13"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF14681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0020645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="218" mass="24249" checksum="F64AE455D0A00016" modified="2023-09-13" version="1">MSYQPPPQVIQLPQTQQLRALTTIIRDKDTQRADFIFYSDRIIRILVEEGLNHLPVVEKSVITPTGKEYHGIDFQGRICGVSIMRAGESMEQGLRDVCRSVRIGKILIQRDEETCLPKLYYAKFPPDIASRFCLLLDPMLATGGSAIKAIETLIDHGVAEERILFLNLISCPEGISAVVAKFPAMKIVTADIDEGLDAKSYITPGLGDFGCRYFGTDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N334</accession>
    <name>A0A9P6N334_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Nucleosome assembly protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_000652</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the nucleosome assembly protein (NAP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000114">
        <property type="protein sequence ID" value="KAG0022255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N334"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1120.90:FF:000003">
        <property type="entry name" value="Nucleosome assembly protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.1500:FF:000001">
        <property type="entry name" value="Nucleosome assembly protein 1-like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1500">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1120.90">
        <property type="entry name" value="Nucleosome assembly protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037231">
        <property type="entry name" value="NAP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002164">
        <property type="entry name" value="NAP_family"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11875">
        <property type="entry name" value="TESTIS-SPECIFIC Y-ENCODED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00956">
        <property type="entry name" value="NAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143113">
        <property type="entry name" value="NAP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="111"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="274"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="325"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="16"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="115"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="281"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="333"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="365"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0022255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="376" mass="43312" checksum="868887E29530E72B" modified="2023-09-13" version="1">MDQSSANVDIKKKQQEAPTPQNTPIFTAPINSSARPSVPVIEEDMETIQTPGYIQSLSPDVRRRVKGLKSIQKKHTALEVEFQKEILALEKKYLELYTPLYQKRAEFVSGKAEPTDVEVEEGVSEGEEEEEEEKEDEDDEKDAEKVEGIPEFWLTALKSHPQFADIITEKDEGALKHLVDIRLSYFDKPGFRLDFEFSPNDFFTNTTLTKTYYYQDEPGYGGDFVYDHAEGTKIEWKEGKDLSVTVETKKQRHKGTNKTRVVKKTVPAETFFSFFTPPVAPEEDAEEDEDEEEDIDEKLEIDYGLGEELKDNIIPRAVDWFTGKALQYQDNNDQYDDDFEYEDEDEDEDEDEDEDDDDDDNGVPAKDEKAPECKQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N339</accession>
    <name>A0A9P6N339_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_001340</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000130">
        <property type="protein sequence ID" value="KAG0021963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N339"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050562">
        <property type="entry name" value="FAD_mOase_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356:SF2">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356">
        <property type="entry name" value="FAD-DEPENDENT MONOOXYGENASE ASQG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="13"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="290"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0021963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="452" mass="50814" checksum="B52F0E6E88A459FD" modified="2023-09-13" version="1">MSQRPPTDRPVPEVLIVGAGICSLTLAILLEQINIPYQIFERASVVKPLGSSMVFAGNVFPVLEQLGIYEEIKKVSNPYDKGDYYDGNLKKLGSFNVEQCKIATGYDCRVFARPRFYEILLKRVPAHKISFKKKVVRTEEKDGKVTIYCSDDTSYTGDILVGADGAHSETRQNLYKNMDEKGILPKSDLEDFSIGHTTIVGVAAPSNPEKYPQLKSERCYVAALPDNQIGWGFGQQLSETDVKEIQSRNSEWGPQARDTAYAILEKYRDFPSPLGGTMGEIFDATPRDLISKVLLEEKLFKTWHHGRTVLLGDACHKFHPAGAQGAMNAIFDAVILANGLYNMNDTSDKSITTAFEYYSSQRYHRTEAGFNESVAMAKIMNGQANLLSYEYDYSALLKKWSERLIRNVVLNYIPSFIMDAQLRKILAYRPQVAWLPLVENRGEGPVTPQEFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N398</accession>
    <name>A0A9P6N398_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein 18</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_008686</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000048">
        <property type="protein sequence ID" value="KAG0023648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N398"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026721">
        <property type="entry name" value="TMEM18"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14770">
        <property type="entry name" value="TMEM18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="187"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="47"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0023648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="235" mass="25620" checksum="9B5408BF37E0A25B" modified="2023-09-13" version="1">MSSSTGQSPEGTSQFWDDFWNTIYQFTHPFSSSFFDSLLNGDESDTAGSGSSPSSQPVGSAGKGSPSNEATESQGSGTYRFKDRPSFEKFWNDMKKSADGHDSSPSTLLEHIQEAWTDAKTTATGFISSVLLHAIYALLSHFGMITPNPLAAMLFCTILLAALSEPLNGIGSRHWREFSDDNYFDSYGVFTSLVWSAPLLGNAILAVLLLLRATAGLLIKVKKAQIQESKRKKQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N440</accession>
    <name>A0A9P6N440_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_011001</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000083">
        <property type="protein sequence ID" value="KAG0022850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N440"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="434"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="499"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0022850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="508" mass="55150" checksum="952CE5AD751C4455" modified="2023-09-13" version="1">MTPRKLATAADFSALTSSLNALYTNKAARAETTPSITHSKDATDTVDNAICEAEELALPSVVIPDRREPVLESTSHSLTENTTDDDHPLKHPLSDPWQQRSFPDPPGSQEESEEWKSQACNQHSNQSQAIITADDVQIHSRQCKEESISSTISSASDQAGRGPSSRHFCAASDEFTGRLDGKDIPRKKDHDHPILTNIACDEKTPDETVNLHMAEDATGRQASDSAIDCTPKIDSAGDLACSRWANRATEPKIDSVGTCIASTSRFLESKNIISLSEHKWSQPPQQQESRDVRGSALAKIEAIDKVKSKLKMISLTNASTISRLTVAEKLVLIQQGRGIARLKDPFMPLQIRNECSANKPPAAVEHEHSHYRGSTSGKCANDKKKIRYSREFLMSFRHLTTPPRCIESVMATIHGEAGRPLVGDTARKSILATDIRSGESDQALPRSGKPNDAPSGNVHRSSNTSSGGGRVFSFKIRDPKGPPSKSSSGPPLGFRSRVNAPQASLTPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N459</accession>
    <name>A0A9P6N459_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_010674</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000077">
        <property type="protein sequence ID" value="KAG0022986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N459"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24296">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="472"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0022986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="531" mass="60467" checksum="A339B01EA2E7EE48" modified="2023-09-13" version="1">MTSATAAPNSGARSQLIITLAQLLTKVFSRSNISKTLGAYLLFIIFKYRDCAYGVRRRPDLPGPRGDPLLGNTIGMLKRLRTENYQQQTENHEVKYGRCYSVSFPGVGRIINISDPEMIEHVLKGNFWAYVKGPFLRKTLEPLVGQGIFGADGEHWRWQRKLASHIFNVKSFRTYTSDVFCREANLVIDYLSTVADTEKIVDLQSIFYLFTLDSFGEIAFGQAFGCLNDPEREVEFAASFDRLNHSLSGRIISPIWKFRDWWTGNGKIVERDTKIVHEFAYNVIRKRREELANGEKAERNKDLMQLFMDGTDENGQPLSDEMLKDELINMVLAGRDTTAQALSWMFYLLHRGQTSSEIISQLTEEIDSVLNGAHPTYESTKQQKYAEACFYETLRLYPSVPQNLKLCVEDDVLPGGIRVYKGESVGWCSWAMGRLEYIWGPDAKEFKPERWLAGEKPSSSKFVSFHLGPRTCLGQQFATIEALTIISMLLQKFTFELVDPNQEPAYLPSLTLPMSTGLSVRVKRRVESAKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4G3</accession>
    <name>A0A9P6N4G3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_004765</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000024">
        <property type="protein sequence ID" value="KAG0024251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N4G3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="258"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="291"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="45"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="10"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0024251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="415" mass="46146" checksum="B28175DD56DC829D" modified="2023-09-13" version="1" fragment="single">MHSHIEDPHMQTTDDTETLVSSTETLHDAIRNKHFSHISADSIATTTFDDDDDDRRDRHRRSNSGSDSVYSVVTEATEPHSNYKSSPTDIPSTTTITPMLNLQSGEQIDPWGANPYDQDDLAGTLRFKRADSDEDDDANTRNSITGLASTTATADLSSQEKIGISTDTLARLDHEFEMLTKGQAIQITTTSTATGLDFAREQLDDPRGIVGRSITDKDKRIKMCKLFSRASSNGDMNRVADMLDNFRDWIDIEAQDEDGTTPLIYAACFGHTEIAFMLLEAGAKVDARDKFGWTALVWATNNKHENIVRLLLEQGASTSAQTAKGHTIVDFLRHDPNDNAKIVQVFQEPCRRDSVSSNGSLFRTNNSSLGDDFFYQSGIEGFEEIMAENERRYKMAMESANAFEVDMADLSLADQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4I0</accession>
    <name>A0A9P6N4I0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Photolyase/cryptochrome alpha/beta domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_009801</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="6">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA photolyase class-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000062">
        <property type="protein sequence ID" value="KAG0023307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N4I0"/>
    <dbReference type="OrthoDB" id="435881at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003904">
        <property type="term" value="F:deoxyribodipyrimidine photo-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032922">
        <property type="term" value="P:circadian regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043153">
        <property type="term" value="P:entrainment of circadian clock by photoperiod"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.579.10:FF:000003">
        <property type="entry name" value="Deoxyribodipyrimidine photo-lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.579.10">
        <property type="entry name" value="DNA Cyclobutane Dipyrimidine Photolyase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036134">
        <property type="entry name" value="Crypto/Photolyase_FAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036155">
        <property type="entry name" value="Crypto/Photolyase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005101">
        <property type="entry name" value="Cryptochr/Photolyase_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002081">
        <property type="entry name" value="Cryptochrome/DNA_photolyase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018394">
        <property type="entry name" value="DNA_photolyase_1_CS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006050">
        <property type="entry name" value="DNA_photolyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455">
        <property type="entry name" value="CRYPTOCHROME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455:SF18">
        <property type="entry name" value="SI:CH1073-390K14.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00875">
        <property type="entry name" value="DNA_photolyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03441">
        <property type="entry name" value="FAD_binding_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00147">
        <property type="entry name" value="DNAPHOTLYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48173">
        <property type="entry name" value="Cryptochrome/photolyase FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52425">
        <property type="entry name" value="Cryptochrome/photolyase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00394">
        <property type="entry name" value="DNA_PHOTOLYASES_1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51645">
        <property type="entry name" value="PHR_CRY_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0157">Chromophore</keyword>
    <keyword evidence="4 6" id="KW-0274">FAD</keyword>
    <keyword evidence="3 6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Photolyase/cryptochrome alpha/beta" evidence="9">
        <location>
            <begin position="103"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="22"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="341"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="392"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="395"/>
            <end position="402"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="493"/>
            <end position="495"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="site" description="Electron transfer via tryptophanyl radical" evidence="7">
        <location>
            <position position="427"/>
        </location>
    </feature>
    <feature type="site" description="Electron transfer via tryptophanyl radical" evidence="7">
        <location>
            <position position="480"/>
        </location>
    </feature>
    <feature type="site" description="Electron transfer via tryptophanyl radical" evidence="7">
        <location>
            <position position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602081-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602081-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0023307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="593" mass="66737" checksum="8AA26E8A488BC423" modified="2023-09-13" version="1">MPPKKRPAGDDANGDEPRKRPAAATSTAAPKSVTISAPGTATAAKPATTAARSSTTSKTGTVRGAPKPGIRKVGAAALASRSRLPIAGSSTLKKEAPPPIITKNTLMWFRNDLRLRDNKALHAASLRAKLGDEKCLIGLFIISEAEWASHDEAPVKIDFWMRNLAMLKKSLDKLHIPLVIKRASSASNVVGIVESTVKEMDISHVYWNVEYMVDEMKRDAAVKKALEKLPGIYVEQHHDQGVIPPREMADKTGGGYTSFEPFNSTWNTRVETKPHYLQLSASPEANPIEAKQLYAEHFNSMIPSLHSHTLERVETEHLYPAGEEVAHERLRIFIEEKIKRYHLSRDCPHEEGGASLAPYLSSGVLSARQCVAAARAANNNKIIIGNEGVRTWIRELVWMEFYRHVLVYFPRVCKNHAFKPIMESIRWSTDDRKFQMWCQGKTGYPIVDAGMRQLNTTGYMHNRVRMVTACFLVKDLLINWQKGEKYFMGHLIDGDFASNNGSWQWCASTGVESPPFYHAFNPILQSQKFDPNGDYIRQWVPELKSLSDKQIHDPYHTMSAKEFGKLAYPKPIVDHAEAKKRFLEEYKRILVPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4X9</accession>
    <name>A0A9P6N4X9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Peptide hydrolase</fullName>
            <ecNumber evidence="14">3.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">BGZ80_008591</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the peptidase M28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="14"/>
    <dbReference type="EMBL" id="JAAAID010000047">
        <property type="protein sequence ID" value="KAG0023677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N4X9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.10:FF:000008">
        <property type="entry name" value="Endoplasmic reticulum metallopeptidase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053974">
        <property type="entry name" value="ERMP1_1-A_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147:SF22">
        <property type="entry name" value="ENDOPLASMIC RETICULUM METALLOPEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="METALLOPEPTIDASE M28 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22249">
        <property type="entry name" value="ERMP1-TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4 14" id="KW-0645">Protease</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="9 14" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="71"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="420"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="446"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="481"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="514"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="540"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="570"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="611"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="642"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="18">
        <location>
            <begin position="207"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="Endoplasmic reticulum metallopeptidase 1/1-A TM" evidence="19">
        <location>
            <begin position="445"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="143"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU361240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF22249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAG0023677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="907" mass="101922" checksum="4AA2B39CBD5124EB" modified="2023-09-13" version="1">MASISNAALKQRHMKPANDDVNNTQHFGSLDNPFFEDEMMNKKLYPESQNDSFDLQLLYLRFQRRHPYTTAWLLYLGFLFSLIFFACQIHYALPSPVPSELGAVLDPATGLYQHRFSEENVRKIVRHLSEDIGYRIVGTEQDQETQEYLINELKQLKEQAQQESTRLRAMQSDKDVAIEIALPQFDMWVQVEDGSHQFDFMSKECDKNAILLNAHYDTTLGSPGAVDDALPVGVMMEIIRIVSQRPTLKKNMFNGGEESLQDASHSFITMHELRHSIRAVINLEGCGTSGPEILFQANSKPMIEAYSRVPYPHGNVMGNDLFSTGVVLSDTDFRQFVDYGNLTGLDLAVYKNSYLYHTHLDLDELMERGLPQHIGENTLALATYLADEVDLTSSMERTKAVVYFDVFGQFFVSYSMETAIMSHIFIGVLVVITLVTGASRPTVRSLVSVVLSFISALLTPLFSVIMIQALGKSMIWFSNEWLPVVIFGPLSAAGMLYVQWLFHNTRIASGTNELNTLSSIQVSYTIAMAAASVLGIASSYFLAIYSLFTSVALIFNHKRTASQKKSGVDYTAYYVASAIQTFYCSHLAFSLYDLIVPLTGRIGVDAPVDHIIAIMTGFTIVSFSPPLLAFSHRFGCSSLKRAISRLVVLQIVIILVCSAILTPYDTLHPKRVFAQHMRNLTSGESLMYVAHADAGPFYSPYITQIESLYDTKATFRSGNGNNGDWKSVYPFNQFLDSYVFDTTPYIRKHTTNATLSKSSAPLTDLIQRPPVLYSENVSYNPETGLRKLTILCTHPNYIWTVTSFDAEVVSWSMKLEVPSKEKFHYVVRHAGGYKSDGWRLDLEYRAAGIDDKLRVELTAMETEGFGRDIERELEGSGDIGVMRRLVKARPDDVSLTYFSSVLSNFDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N540</accession>
    <name>A0A9P6N540_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_006473</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000032">
        <property type="protein sequence ID" value="KAG0024029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N540"/>
    <dbReference type="OrthoDB" id="2425461at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="54"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="233"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="127"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="338"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="19"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="233"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="250"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="269"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0024029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="372" mass="40888" checksum="11384EC3597FA16D" modified="2023-09-13" version="1">MPSTDSTMQSISAPILVPGTQQEPTMPSISSPVTSNIPTVTNNHRASLPITRASIHNGGSASSSGAGVGNNTNSGLGRFPSIGNTKKLTVENMTLKAKVTELERYVVGMKGELMLFTRKSHTLQSEIKEAEDLHATETRKLEEHINRCEFELGAKVIECEALNDQLIEKERAHQQLLQLLQEQEQKRAQQEQQNEQRDEKIKALMEENTRKDALINELLKKVGHLGTELLNIEREKAHLERDPSPTSADTTMAETTPSTSTHNLTIQTQAEELSDSQSDSSLNASTSTSPTTIQSENEECALTHSDSTATTFVNSVGYDVSLEHPKLLAKFQALRIQHAQTSEYLELLENENQELKVQLLDVSNGSGTVAAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N5V6</accession>
    <name>A0A9P6N5V6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">DUF221-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BGZ80_003730</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CSC1 (TC 1.A.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000020">
        <property type="protein sequence ID" value="KAG0024385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N5V6"/>
    <dbReference type="OrthoDB" id="2150324at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005227">
        <property type="term" value="F:calcium-activated cation channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045122">
        <property type="entry name" value="Csc1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003864">
        <property type="entry name" value="CSC1/OSCA1-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027815">
        <property type="entry name" value="CSC1/OSCA1-like_cyt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032880">
        <property type="entry name" value="CSC1/OSCA1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018:SF149">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G11660)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018">
        <property type="entry name" value="PROBABLE MEMBRANE PROTEIN DUF221-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14703">
        <property type="entry name" value="PHM7_cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02714">
        <property type="entry name" value="RSN1_7TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13967">
        <property type="entry name" value="RSN1_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040136089" description="DUF221-domain-containing protein" evidence="9">
        <location>
            <begin position="17"/>
            <end position="1008"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="44"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="271"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="316"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="364"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="499"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="537"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like N-terminal transmembrane" evidence="11">
        <location>
            <begin position="2"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like cytosolic" evidence="12">
        <location>
            <begin position="89"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like 7TM region" evidence="10">
        <location>
            <begin position="269"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="646"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="796"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="977"/>
            <end position="1008"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="658"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="692"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="710"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="751"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="916"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="937"/>
            <end position="949"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF13967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF14703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0024385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1008" mass="113977" checksum="6A8ADD78ACF93D66" modified="2023-09-13" version="1">MAIVGCFVLIPINVVATKQALQPGEEPSGQVSMLSIAGFSDPKWLWAHVAGSWFFSLVMFFSIYHGYKTFVKFKTRYFESEAYQESMASRTLMLAGLPSSLQTDEKLLKFMNDMGLNEKPVQALVGRKVDKLPELMDKHKKMMKALEKVVAVYYADPNRVPTKRPTVRVGGLCGTKVDAIDYYSQQIEDLTDEIEKTRHEVSKSRPTNYGFVSYGTIQAAHRVAKELSSDITLRKRSKMIDPPEIFLSPLPKDIIWFNVSNPKQLRKSRRIIVNVAFVIGSLFFFIPMGLLTAFAQLNRIIGFFPKTQPFFDSHKFVSSIIQSLLPVLAMDILLLVVRKFIIFLAWFQGNITKSSTDRSTLAKFFLFFTLNNLIVPAIVGAMLGFVSQIKAVLASFSFSADTWHAILSLLNFKENIVDMISQNVVDTSLFWVNYISLRNFSALLDLSQAVSLAMYWAKTMTPRESKALNKPDVFDFPLFFSVHLFLLTVSLLYSVVAPLVLFFALVYFSLASLVYKYQLMYVFRTRVETGGRLFRVIYNRIIVSLVLFQVVMIGILNLKGAHKHSYATIPLPILTILFKIFLAKTYDPKIDYYDYGSAHEERHLFKAKGKGNMLLLNFENPALKSKVVSALVPDAAKKVLSKKVLQGEQDSKEGKNNGGHHGKSHSRGKHSFSQRNGSAEHMDEMESYEMSHVSRDSKERFNENKKSYEPQRSLSPQRQQRFDYRSQQPQHVLETDDPVDDYYDDQKESLTKSATQSYSDTYSTHSRQQSNSHSSPAKVYRAQDMTSFVAGRYKADRAADPYSYSSSNKGGNGDSADSKPSVMELARMHQTDNYKNTGKATQYDDRKPLHLPPVNFQLPKIHATTSRGQHQTRRTGGGHQDPLTDNGADQDIHDQYNEEPTTPTTPRPSRMPLPQRSNPTSSTNTSTRRGYKDGPALHHASSSPSLVSSNKCGNEYSNDTDLAYAPPSVKELTRAFTQGDVQKPKNTYNDNIVSSSRGRNNDYTTRNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N6L7</accession>
    <name>A0A9P6N6L7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Arrestin-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_010827</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000008">
        <property type="protein sequence ID" value="KAG0024670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N6L7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011021">
        <property type="entry name" value="Arrestin-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050357">
        <property type="entry name" value="Arrestin_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188">
        <property type="entry name" value="ARRESTIN DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188:SF17">
        <property type="entry name" value="FI21816P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00339">
        <property type="entry name" value="Arrestin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin-like N-terminal" evidence="2">
        <location>
            <begin position="94"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="428"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="493"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="51"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="437"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="457"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="467"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="499"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="556"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0024670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="556" mass="62269" checksum="2282A1A752EECE56" modified="2023-09-13" version="1" fragment="single">MSEVSPATTVHPSQHLTQVEHHDTSRPHGQRHRRTGSNDSTHTVTTGIPGPSTHHPSSSTSQRSEGLISTLAVKSSPIPKLFKVEISNNGDCKSSNPIFYPSDLIHGMVYLYIDKPMTLPALKIVFRGESNYPRSKQQDQLDHHMRRLFSVAMTLWGTRGTTPEDQWGELPAGNHIFPFTIQLPDKNLPASFDHPWLKNQYHLTAYYRRPNGLSKWQSKAKPVNFMPLSTPGMEHGPIRERCPKMGTVLLLSRPDQTPGGQVHVKLTAEAAIDRCHFSLSRHIRARINETIYREDEVICHYERKSIPKGEFNLVLPIPKITPPTTESSSALKITYSVQVSIWNERFFFKTESHNFDLPIVIRTLPSCDNRACEGLDWCEPSIDRPMFLTEIPIQPLPLYDAEQSPPTYTQDLPEYDQVISAPSALGSMPVNEEEEDHPGHDNDRASTHSIESANSDVEGRETEPNRIRHSHHSRPHHPSCVYYVAPLDRIDDQTTERQSSTLSLESASSSSNASASDDASSSSSQQNNNSLLEGSSCPTAHAQAVDIFKVHTIIES</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N6Q8</accession>
    <name>A0A9P6N6Q8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_002064</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000015">
        <property type="protein sequence ID" value="KAG0024504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N6Q8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="295"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0024504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="339" mass="36348" checksum="65ED78BA3B51B73F" modified="2023-09-13" version="1">MQHYSRSGYGHDDATFKVLVLGDSGVVGTKTITSPSPESSSNTSGAETFIEFYDISGSPAVRSPKSRTMFYSGATYQGLILVHDLCNKRSYENLWRWIGDYMEGSQASGRGPGYNGGEYGHLSIPLLVVGTKNDIPASYDQQGAGPKAHGFNLVEKYGGEAMSVCAVSPADFMPSSSASIAFNMFFSRVIDPSSINVSRQRSPLSSTATYPSGAAPIFARPPPTPTPQEVRSQYPEHHTNDSSSGPLSIPILDFATFTGGSTTDSIEDHRVPTRSGSPMSQGQNPTRPITPTEVSSSAATTTKSALRAQYERNRSVLNQYNNMGVPVYTSRSTTPTGPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SQF5</accession>
    <name>A0A9P6SQF5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008929</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010005006">
        <property type="protein sequence ID" value="KAF9991755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SQF5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9991755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="59" mass="6605" checksum="9CFF1DD71F9227B6" modified="2023-09-13" version="1" fragment="single">MYKQLGEKENLPLGDKDSFSIGYINMVGISTPSNPEKYPELSDKTRSHSRLVMGDNNDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SR55</accession>
    <name>A0A9P6SR55_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008485</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004606">
        <property type="protein sequence ID" value="KAF9992610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SR55"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="47"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9992610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="148" mass="14791" checksum="2A2EA9E70A0F17E9" modified="2023-09-13" version="1" fragment="single">MLAFSGFYLKKRDSSALRRRAAHSSSVQASKTDSKAASKTDSKADSKSNTTSTTSTTTTTTTTTTTTTTADSATTADSTTTTTTTTTTADSSTSATTADSSTTTTTTTTTADSSTATTTGSTTTIGSTTTNSTTTIPATTNSTTVSAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SRT1</accession>
    <name>A0A9P6SRT1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_007618</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003930">
        <property type="protein sequence ID" value="KAF9995061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SRT1"/>
    <dbReference type="OrthoDB" id="41532at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050769">
        <property type="entry name" value="NAT_camello-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13947">
        <property type="entry name" value="GNAT FAMILY N-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13947:SF37">
        <property type="entry name" value="LD18367P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="112"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase" evidence="3">
        <location>
            <begin position="140"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9995061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="323" mass="36742" checksum="40C418AEFD69A27A" modified="2023-09-13" version="1">MPADIDRSAILIRPYNRDDYDQVSSILIQGFKSVNGRFFSSKASHYTTFLSIFIRSTVYTILVEIALTAYFNLQSSDSNYFSLEDLRSLYTVLTQDESAQSLILRFLQPSLLIVWVIVSLATGVSTVLGIYRWAISTGDDYIESAFKDDLGDIEGYYQSTSSTNQKPNRSQFWVACLKDYPEIVMGCIALDDVSAHAESFKKKHLQGGGKESTFEAPKKTDAELRRLSVHPNYRRLGISRMLTEKLVAHAKENKFDRVYFMTTIYQTAALAGYIRFGFDKEKMLTYGDFVKIWCGTLNLNATKEEKEELRRKQESLLAEVGAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SSD8</accession>
    <name>A0A9P6SSD8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CUB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_007254</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003685">
        <property type="protein sequence ID" value="KAF9996396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SSD8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9996396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="156" mass="16741" checksum="7979720F60CB9EC7" modified="2023-09-13" version="1" fragment="single">YFNILPHGVSAASALTSQPGVTTNDNQDVQHVPDLDYNVDHSMYLRTFTSFALRDGADGAYDQSNQELSPEPSSYLPRGWRDSSSYSRPYAVSKETMIAQTICDSNTVQVLGPGWGSTFMSNSQDGNYPSGNRTCIWTIQASTNATGGGGSATPSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6STN6</accession>
    <name>A0A9P6STN6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Class II myosin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">MYO1_2</name>
        <name evidence="7" type="ORF">BGZ80_006429</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003176">
        <property type="protein sequence ID" value="KAG0000072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6STN6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015629">
        <property type="term" value="C:actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051666">
        <property type="term" value="P:actin cortical patch localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097320">
        <property type="term" value="P:plasma membrane tubulation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11858">
        <property type="entry name" value="SH3_Myosin-I_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000072">
        <property type="entry name" value="Unconventional Myosin IB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046982">
        <property type="entry name" value="BIN3/RVS161-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035535">
        <property type="entry name" value="Fungal_myosin-I_SH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47174">
        <property type="entry name" value="BRIDGING INTEGRATOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47174:SF3">
        <property type="entry name" value="BRIDGING INTEGRATOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="6">
        <location>
            <begin position="55"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="119"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="14"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="37"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="119"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="174"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="209"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0000072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="278" mass="27945" checksum="B6A10E4B695DDD0A" modified="2023-09-13" version="1">MNQSQGSRRPPTSTPKATPVSPKAATPASSSTTPAKRQPPPPPPAPVAEAPPAAPAKPMFKAIYNFESQDAGEVSFVKDDIMEILEKDENGWWLAKKDGKEGWVPSNYLVEVPAAKPALPPALPAKRQPPAPPAAPAAPKSNNTPSVTKHTPVVTATERISVAATSNTSAVHTGFGGPGNVGGVPGWKVALEAKKAAAAAAAAGGGGAPAPAAPSTSPTPAARRPGPAVSPKPAVGAKPTLPARAPVAGPKPTAAARPSTGGKSLQEILAARRQQNED</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6STU2</accession>
    <name>A0A9P6STU2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">60S ribosomal protein L3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPL3_1</name>
        <name evidence="5" type="ORF">BGZ80_005950</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002933">
        <property type="protein sequence ID" value="KAG0002571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6STU2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000351">
        <property type="entry name" value="Ribosomal protein L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045077">
        <property type="entry name" value="L3_arc_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000597">
        <property type="entry name" value="Ribosomal_uL3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019926">
        <property type="entry name" value="Ribosomal_uL3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11363">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11363:SF5">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00297">
        <property type="entry name" value="Ribosomal_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00474">
        <property type="entry name" value="RIBOSOMAL_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0002571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="279" mass="32139" checksum="21BC3C3B46F26A78" modified="2023-09-13" version="1" fragment="single">HLSEELKRRFYKNWYRSKKKAFTKYAKQHANGAKPVLRELERIKKYCSVVRVIVHTQVRKLKIGQKKAHVMEVQLNGGSVADKVNFAYEHFEKTVDINSVLEQDEMIDVIAVTKGHGFEGVTHRWGTKKLPRKTHKGLRKVACIGAWHPSRVMFSVPRAGQHGYHHRTEVNKKIYRIGKGEDKSNAKTEYDLTEKAITPLGGFPHYGIVNEDYVMIKGCCAGTKKRVVTLRKSLLVHTKRSALENVQLKFIDTSSKFGHGRFQTREEREQFQGTLKKDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6STY4</accession>
    <name>A0A9P6STY4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005922</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002918">
        <property type="protein sequence ID" value="KAG0002722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6STY4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0002722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="249" mass="27920" checksum="66CD433AE0CC161C" modified="2023-09-13" version="1" fragment="single">MFPTPVQAADTEVGNAIEGLHKFFYEERPAQWTPTHFAKRPDATDYYVYIKGLHRIKNEGPISLSTYCASIIKFLKEDPHGIEEESEAKRSIEVRTTIQIEKEEELIFKSNISTNFLKRRSEEESSTEAQTSWKPKSRFQLAAGCSTSPLSGSPLSYPRTPSPLRSGTAEHNSFLAHFNGFQDSSDSDSARIINSQINTASNLPVINTTPAFEDVEQFFQNEQLLQDAIVDSLQSGKFYGLGQRATRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SV51</accession>
    <name>A0A9P6SV51_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_005439</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002682">
        <property type="protein sequence ID" value="KAG0005502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SV51"/>
    <dbReference type="OrthoDB" id="2343555at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00882">
        <property type="entry name" value="Ras_like_GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="454"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="domain" description="G" evidence="2">
        <location>
            <begin position="569"/>
            <end position="672"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0005502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="771" mass="89080" checksum="14F62DFE7BF1EA83" modified="2023-09-13" version="1">MAIDQDFDKYLGRCFNPISDKECPNYYIDPAMVGSQTINKVRIRVNYYSSSAEYNKNRNVNVDGGVSTPFEIVGLNMKYDKRTHESGRQNTSYYVYNCEVINYRVFEKRAGIKSKSSANSYIYNVQYGGYLRVIAEITKEHANVQLNNFSELDVGLTEIHSSINIFTDFLRTKSDNHRYDTFRYHSSVEHSGHAETSSIDADNMEAVVNTFISNVQHNRRNPVALYYTYNTLDPSVIQINRKNHAFLRRNRDQIKNSSSPNTAPMLNEMDKLLKKLENADIVNQSQFDYHYATICDHHPELSSKLINFQFYTYVTKYKKIKEMPIHLLLLKVLDSARYNSNAADVAKIKTSLIQLEQLCSRHCDGETDKHFKERVNKYIDYADEKLKYANNQIESDGASILSNHTYVENNDIENTFMHGYDVIHNTFYSRHKIMRFLSKDKYVDTAYEFEASDVGWGALAMVLSPFILLASPYFLWQGLKDVRKRRLYSTKEFLENTNISYHNNVQRCRNLARGVYVGNSEYIEDNVANVSNYSVFSDRAKRYKDARDFFDSVKLIKSLRDLEINRFVIAVIGNTKVGKSSFLARLGLKSNARAGVHTKQLTPHMLGGVMFLDFPGNDDTDEVIRNEFLQNYRTVDMCIVVSEINKASTDGVFSLIDKLRIANDIPYLVFLNHCDRVIDDDENDEELSVDTFGEIVNEKTAKVTQQFHQNGIKTLKIYPTSFKRNVRNLAHYGVISVRDVMFIVKQLLDMENIHYNEAQLFEHIGGIKCSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWH8</accession>
    <name>A0A9P6SWH8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">GOLD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BGZ80_004173</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Endomembrane system</location>
            <topology evidence="7">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 8">Membrane</location>
            <topology evidence="1 8">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the EMP24/GP25L family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002155">
        <property type="protein sequence ID" value="KAG0007837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWH8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015720">
        <property type="entry name" value="Emp24-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009038">
        <property type="entry name" value="GOLD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036598">
        <property type="entry name" value="GOLD_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22811">
        <property type="entry name" value="TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01105">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01190">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101576">
        <property type="entry name" value="Supernatant protein factor (SPF), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50866">
        <property type="entry name" value="GOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0732">Signal</keyword>
    <keyword evidence="3 8 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040476838" description="GOLD domain-containing protein" evidence="11">
        <location>
            <begin position="30"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="188"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="GOLD" evidence="12">
        <location>
            <begin position="41"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="128"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0007837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="222" mass="25195" checksum="D4EAAB2D1765DD1C" modified="2023-09-13" version="1">MILTKTASMTMLVMIALISISLLSRTADATALTYTVEAHEKACFYAWVDVPKKKLAFYYSVQSGGSFDIDVEVKNPKDKVLLSLEKDRQGDYVFTANDVGEYSFCFSNDMSTFAEKVVDFEISVENEKRPAQADQKEKGQGTQAQAEAMDESVFRLSSELARIDRMQKYFKARDNRNFSTVVSTESRIFWFSLTESVMIVAMSMVQVYVVRTFFSGSRRSHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWN1</accession>
    <name>A0A9P6SWN1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003151</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001817">
        <property type="protein sequence ID" value="KAG0008699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWN1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="142"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0008699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="387" mass="43441" checksum="45D17699AB91D24E" modified="2023-09-13" version="1">MFPAPPPKEDLSLNLEGLHEFFYGNEPERWTPTQFASHSMATDFKDYIRSLHRIKKNGTQCLRVYCSDIINYLETDPHGKDEEEQAKSSIERRKTFRMEKEVELVAKSKTNINLLKGISKDESESRHSSNNQAPKATPSLASRTTSSSSRKPNPISSSRTNPSPTTSIPHIMYDDVSDVEEPGQGHNEELYDNVIDVDESDNGYDVEESDDGYDDDEDKGGDENNSGDDAKELKLISATSPFDDLVAVLFRIYNHRVSTVATISPPLSGTLKELHAYASLNLSQWERIPDTRKKSTMLALSGILNTMDNGMQYFNDFAVTKAACFEEHFTSPSAEMKSIIDEFLGAMGTERSLRTLKTYCREQQLESTKTGCEGSDRARVINAVEYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWS6</accession>
    <name>A0A9P6SWS6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_002976</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001761">
        <property type="protein sequence ID" value="KAG0008870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWS6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0008870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="225" mass="25867" checksum="11CA05590737E150" modified="2023-09-13" version="1">MNTGNMDNFLAMNSIWNTEFQLKDLDTTTHTKIKEEYNQSRVELPDEIIMLCISLDREMESTGRIKPRSASNDFQEDIIHIYQTLIRKLPRRALSFIQGYEDTFAHSSMDALFTTVFPANDCYELDWANRPADGSKERRGDALKPDATILKSCYELAFVEVKPPKEDRTARPYLEDLWKLANFCKDAIDNHITYGRGFITKTAGIQIYGKSDALTKLLLNLSHDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SX16</accession>
    <name>A0A9P6SX16_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_003290</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001862">
        <property type="protein sequence ID" value="KAG0008579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SX16"/>
    <dbReference type="OrthoDB" id="2390179at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="193"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="229"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="258"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="292"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="330"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="375"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="405"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="435"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="592"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="435"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="465"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="596"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="631"/>
            <end position="642"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0008579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="642" mass="70538" checksum="BA70EF0276C42DA1" modified="2023-09-13" version="1">MPTVDAGLAVRINASTTIDYRSWDPFQGQANYYSISGVMLLGEVQDNCTVNIDTAAGPKARTLMAAVDPQDPIIYTILLLGYDWLNYCSTFDDIFYNVDSTNTQLRSIALPDIGAIVMDGNANSNEDFGSPFTQLADGSRWNKDVHLNISFMGSDDFLSLSSLLAANNQTLLATVVEELGPWNEMWHSIGFNILIRALDVFAAFTFVYGVWVIVYIAKANQEMQHTRRFMILVPGCIYLPLSIAFAPYKTTLPWRNAVYYFSLLFPFISLGLQMIMWGILIYRIHRKKMNKVFSYFAYITILVPSVSAFLDGIGWLVPSVPTIRMIGERGFSYATPAVILVQAVVIFYYAITFFKSLRGVAVSQTTRTALTKITVLNLAMISFFILMLLSRIVSVMGLDMKSCSAYIVELAVFRFSFLLFYACCFRTMSLRQPTGSTVDSKGASSADANHSNGATKNSSKNHTHYHMDTLSKDSSTKSGQQGGNDGDESKSGTHYNKHLSNHVSKGFTISDPSNYGTAAYGGPILSPKLPQGFTSQQQLLQIDAADYPDPYKFDEFGHTNAQSTTSAPTDAGVLGDSYIDIDGAGEDKDSVYGSHRFQSSPNSKHVQIGNGNGGRVVGGKATNSEGYTRFDVSDEEHSASAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SX31</accession>
    <name>A0A9P6SX31_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_003220</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001840">
        <property type="protein sequence ID" value="KAG0008642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SX31"/>
    <dbReference type="OrthoDB" id="1918565at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0008642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="205" mass="22977" checksum="7109091943225E55" modified="2023-09-13" version="1">MKVFPAEMQIAHLDDAKKVQIPRKSNISHWELINHPVHPQDGGPKVANLETVSWLDVAAVFKNQQAGKYKVQWRLNQISAYPDRVFVGTEFRAVVFNKDENPTTDPTISQERAPATRLIPLSVQEFMQHTDRPNTIPARALRMAESMALQGMPGYDPNVQGFFTLTLPDVVQVEQGGGVLAQIRNHEGNLKSGLQIEYAQLVRAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SX32</accession>
    <name>A0A9P6SX32_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_002489</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001616">
        <property type="protein sequence ID" value="KAG0009342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SX32"/>
    <dbReference type="OrthoDB" id="2434096at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040331978" evidence="2">
        <location>
            <begin position="22"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0009342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="173" mass="17400" checksum="C4438F024F492395" modified="2023-09-13" version="1">MYIKSTLVAALAFAASVSAQAKTVFTSPVGGSQVYSAGSNQTFTWLNNCVAPSNLTATDPTKVPVQLLNATVATNAFFLKAITTVDCSTGNQGNVAWTVPTLDNYDGLFSLQMVFIQGNAYSGSFKITPPAGTTTTTAPPATTTTAPPSSGANGVAPALSGAAAAVAVAAMLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXC6</accession>
    <name>A0A9P6SXC6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_002054</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001499">
        <property type="protein sequence ID" value="KAG0009780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXC6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005324">
        <property type="term" value="F:long-chain fatty acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015910">
        <property type="term" value="P:long-chain fatty acid import into peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007031">
        <property type="term" value="P:peroxisome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042760">
        <property type="term" value="P:very long-chain fatty acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03223">
        <property type="entry name" value="ABCD_peroxisomal_ALDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050835">
        <property type="entry name" value="ABC_transporter_sub-D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11384">
        <property type="entry name" value="ATP-BINDING CASSETTE, SUB-FAMILY D MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11384:SF59">
        <property type="entry name" value="LYSOSOMAL COBALAMIN TRANSPORTER ABCD4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06472">
        <property type="entry name" value="ABC_membrane_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="150"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="261"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="362"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="575"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="577"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0009780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="616" mass="70303" checksum="90D1EBD1B964307F" modified="2023-09-13" version="1" fragment="single">MYRLIPTEDEARDEDRTVSGSVREQSEFMDDSSTTKKSRLQFIKDKLKFRPSFLSSTSSCGTHSTTGTKTKGANSTGFTLPKKKKEYLIDMLFVKRLWEIFRILFTSSKVAWLYISMTIFCIVNEAIVYYVGTIPSKYYKVLGDKDSEAFMKLFVTSLLTVFTAGFLFYRILYMHDEEIDNPTVVSRILINPIVDAVFYKESAEGYFRYLHVRFRQFAEPITFSRGEGEALESANEMLELVLKTQLDVIHKELPLKFLQQCVSYFGSILSYVIVAVPIFWGVYDGLPPSDISAVISKVSFVSMYLTFQFTKIIQCTSDFSDLAGYTSRLGQLMEALNEINIEMENIAIDFPHEEALSRDTSIRFENVSFTTPTGDLVITDFDFRFEVGRSTMIVGPNGAGKTSLLRAMGGLWPVSKGQIIMPHEYCKDVIFIPQTSYMPYGSLREQIVYPLTDTASSVSDADVVRVMKLARLENILELIDDFDYTYTHDWNKMLSPGEQQKLAFARLFYSCPMFAVLDEATSSMDTTSESEMFRQCRLLNITCITVCHNPRLERFHQQKVVLDARGGGWSFVQIQEQDQDQDDQDDQDGRDDRPDNSSIARTASRRIDLSLPEDAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXH1</accession>
    <name>A0A9P6SXH1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF924-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_001875</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001440">
        <property type="protein sequence ID" value="KAG0009999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXH1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.320">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010323">
        <property type="entry name" value="DUF924"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06041">
        <property type="entry name" value="DUF924"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0009999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="212" mass="24571" checksum="735A72006F7B734F" modified="2023-09-13" version="1">MNNVAAAAANTSKRLMDTWFKGFVPGQPLGPEMFTLWFGGSKEVDDMLRERFEQDAERALVDREFREQMKSTGEGIIALTVLLDQIPRNIFRGTPRPFVEFDPLARETAKEAISKKLCTHVHPIYRHVLYLPLEHSENVEDQAACIKEFSREYEEVEPIYKDMFKSFLTYAKEHETVIKKFGRYPHRNAVLGRIPTEAERIYLESGGAKWEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXI1</accession>
    <name>A0A9P6SXI1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 15">Pyruvate kinase</fullName>
            <ecNumber evidence="5 15">2.7.1.40</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">PYK1_3</name>
        <name evidence="18" type="ORF">BGZ80_002015</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14 15">
            <text>pyruvate + ATP = phosphoenolpyruvate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18157"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.40"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 15">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 5/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the pyruvate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.40" evidence="5 15"/>
    <dbReference type="EMBL" id="JAAAID010001484">
        <property type="protein sequence ID" value="KAG0009831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXI1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030955">
        <property type="term" value="F:potassium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004743">
        <property type="term" value="F:pyruvate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1380.20:FF:000001">
        <property type="entry name" value="Pyruvate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1380.20">
        <property type="entry name" value="Pyruvate kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001697">
        <property type="entry name" value="Pyr_Knase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015793">
        <property type="entry name" value="Pyrv_Knase_brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015795">
        <property type="entry name" value="Pyrv_Knase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036918">
        <property type="entry name" value="Pyrv_Knase_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11817">
        <property type="entry name" value="PYRUVATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00224">
        <property type="entry name" value="PK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02887">
        <property type="entry name" value="PK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01050">
        <property type="entry name" value="PYRUVTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52935">
        <property type="entry name" value="PK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12 15" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="9 15 18" id="KW-0418">Kinase</keyword>
    <keyword evidence="11 15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13 18" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyruvate kinase barrel" evidence="16">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="Pyruvate kinase C-terminal" evidence="17">
        <location>
            <begin position="99"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF02887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAG0009831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="219" mass="23914" checksum="83FD37879B716B31" modified="2023-09-13" version="1">MMISKCNLAGKPVICATQMLESMTYNPRPTRAEVSDVANAVLDGADCVMLSGETAKGSYPLEAVRTMDETCILAESAICYPPLFNELRQLQKRPTETTETVASSAVSAAHEQNAGAIVVLSTSGDTARLVSKYRPQANIIIVTRKASTARAIHLSRGCYPFIYTEPKVEDWQEDVDRRLRWGMDQAIDVGLLKPGQTVIVIQGFRAGYGNTNTMRIIVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXJ9</accession>
    <name>A0A9P6SXJ9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_001743</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the prefoldin subunit beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001400">
        <property type="protein sequence ID" value="KAG0010159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXJ9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016272">
        <property type="term" value="C:prefoldin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23163">
        <property type="entry name" value="Prefoldin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.370:FF:000002">
        <property type="entry name" value="Prefoldin subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.120">
        <property type="entry name" value="BAG domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036533">
        <property type="entry name" value="BAG_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003103">
        <property type="entry name" value="BAG_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027235">
        <property type="entry name" value="PFD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002777">
        <property type="entry name" value="PFD_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009053">
        <property type="entry name" value="Prefoldin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13303">
        <property type="entry name" value="PREFOLDIN SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02179">
        <property type="entry name" value="BAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01920">
        <property type="entry name" value="Prefoldin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63491">
        <property type="entry name" value="BAG domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46579">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="4">
        <location>
            <begin position="154"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0010159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="344" mass="38493" checksum="A8827DF5F3FA69E9" modified="2023-09-13" version="1">MSSSGSSSSAAASKRPSDQELTQTYNTMKSELNQLAQKIGELETESDEHTLVVETITPLDPERKCFRLVGGVLVERTIKEVLPALKTNQEGIKTVTMQLVQKYKSKEDEFMAFQKKYNIQKKEKAMTVLNIKWGREKKAIDFKDRTLADVKLGELRQKCHEWTKVPIGGLTLIYAGATMKDDNAPLSCFGIKPNGQIAMMGTRPTKSDIRTLTTNGDPEEYAVIVRIQTSLQKAMDLAAEHFPRYQQAVEDYIHSNPGPVNLNQETLPPARKALQDAYTLLSENFLQALLVFDGAVCKPDFEVARGTRREAVKETQKLLDVIDELNARVKACDRGQATQAQVQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZ12</accession>
    <name>A0A9P6SZ12_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glutathione S-transferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_011616</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000956">
        <property type="protein sequence ID" value="KAG0012630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZ12"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050213">
        <property type="entry name" value="GST_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571:SF150">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14497">
        <property type="entry name" value="GST_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="25"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="2">
        <location>
            <begin position="107"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0012630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="256" mass="28795" checksum="FAE3F2A3483E5B21" modified="2023-09-13" version="1">MIQPDATHFSRESTSELSVALNKPESFKLMYWPINAVGAISREILAYGQAKWENLAPGNWQEEKLKTPFQVVPILYIKSQNGQDLVLSESSVIEQYLAKTFGLLGDNDYEEYLIKAFHSSSAAIQSHFAQGVTWEGIEVAKAKHFEFFKSHTLKIWVETHEKHLSDNGNNGHYVGNKLSLADIRTACAIEHFALLPEAPELMEIINKSEALLKVRETVAKDPKIAAWRDSELYKKLSHGSVAFFANPFAFIKAPSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T058</accession>
    <name>A0A9P6T058_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transcription initiation factor IIA large subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">TOA1</name>
        <name evidence="7" type="ORF">BGZ80_010066</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TFIIA subunit 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000661">
        <property type="protein sequence ID" value="KAG0015082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T058"/>
    <dbReference type="OrthoDB" id="6275927at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005672">
        <property type="term" value="C:transcription factor TFIIA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07976">
        <property type="entry name" value="TFIIA_alpha_beta_like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.100:FF:000001">
        <property type="entry name" value="Transcription initiation factor IIA subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.18.10">
        <property type="entry name" value="Transcription factor IIA (TFIIA), beta-barrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004855">
        <property type="entry name" value="TFIIA_asu/bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009088">
        <property type="entry name" value="TFIIA_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12694">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12694:SF8">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03153">
        <property type="entry name" value="TFIIA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01371">
        <property type="entry name" value="TFIIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47396">
        <property type="entry name" value="Transcription factor IIA (TFIIA), alpha-helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50784">
        <property type="entry name" value="Transcription factor IIA (TFIIA), beta-barrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="66"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="140"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="250"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="88"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="158"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="257"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00074154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0015082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="328" mass="35332" checksum="12642157ED925796" modified="2023-09-13" version="1">MANNTVTAVYRFVIDDVITNVRRDFEDMGVDETIMHELQRSWETKIAQSRVTTFQAPEPSAAVEPYSFEEPTYEQPAPASAPAPAPAPTSASAPAPAPTSAPAATSAPSTYTPAHPAASYNYRVEQTPAANLANVASATLPGDNSNVGRPQPHVAPRASNAAGNNNNISLPGGGRNGTGDFSNIPQTDGAADMTELEFMTTEELDDYVEKKFKEAREAERLTGQAPGEVTFTLTLSDRAARKAKRDGLEGFSIGQVDGEDDEDDDTGLGSDLDDSDGDMDDESDNIVLCQYDKVSRTKSKWKCVLKDGIMLINGRDYLFHKANGDFEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0E0</accession>
    <name>A0A9P6T0E0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_009518</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000579">
        <property type="protein sequence ID" value="KAG0015961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0E0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="334"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="341"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0015961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="359" mass="40165" checksum="3B85A8D1EB884294" modified="2023-09-13" version="1">MFSSCDLKPERKVGFTWATDVTTATLADLEAKLCEEYFDSENPYKSTPETFVYAGHSVPVFVKDDDTLHSVLKVCGANFKNRLTISLENHSKGFSDWKFGQVCQMYGLSFSPNLDLMGLLPEFDEIEAAPLNTESRKAFQSLVTEVEAKTQALQLIGSNEATRSLAVASFLVWTTGLFQANMLLACEKTLVGRRGKGSVDYSVHARKNPDFTLSVTEVKKEDFKQRVGQNIVQLDSALSAKKRKRSAYDVGDDEAQNLKSYGIVTDAKEWWFLECTMDVDEQVSLRISKLCDELNFSSNWQDNAKAIFQKLIWLFSRIQEQILVHDRRNKTNLNKRSKAVASSPPASSASASSASTEKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1C1</accession>
    <name>A0A9P6T1C1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Sulfate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_009076</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000517">
        <property type="protein sequence ID" value="KAG0016619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1C1"/>
    <dbReference type="OrthoDB" id="5402974at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015098">
        <property type="term" value="F:molybdate ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031563">
        <property type="entry name" value="MOT1/MOT2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31970:SF9">
        <property type="entry name" value="MOLYBDATE TRANSPORTER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16983">
        <property type="entry name" value="MFS_MOT1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="65"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="108"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="176"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="199"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="247"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="282"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="323"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="353"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="384"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="464"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0016619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="484" mass="51786" checksum="BEBDDC798A174DAF" modified="2023-09-13" version="1">MSEVLPTTHESRNASYGAIVKDNIKDRLSSFKSGFRLGELSGSLGDLGTLLPILLSLVLTGQVDLTASLIFGGVWNILTGIIFRIPMCVQPMKSIAAIALANEMSRGSVMAAGMSVSIAIFILGATRTIHLVKRYTPMAVVRGIQLGTAISFAGKAAKLVKTDGTFWGSSWDWADNYEWAILAFVIVFLFYYRAKRIPVAMIIFFGGLIIAFIKLYTNPPEGVNYPKIGVYTVSVTVPTSEEFKHGFLSAGLGQIPLTALNSVIALAALAQDLFPERPASTPTISISIGLMNLVGCFFGSSPFCHGSGGLAAQYRFGARSEVSIIVLGSLKIFFGLFFGSSLTGLIKCFPSSILGVMLFISGIELGAAARTVNDGVYDDQKRHANFIIMITTAGMLSGFSNDGIGFLGGMVVALCFYLGSRIGGTMDNDNTGVHKEEHLEQSQLEVAAASSGNHDDPSIRKTAIHESEHATEPVQLEETRPARV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1H5</accession>
    <name>A0A9P6T1H5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Fructose-1,6-bisphosphatase</fullName>
            <ecNumber evidence="6">3.1.3.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">D-fructose-1,6-bisphosphate 1-phosphohydrolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">Fructose-1,6-bisphosphatase, cytosolic</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="primary">FBP1</name>
        <name evidence="19" type="ORF">BGZ80_007328</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>beta-D-fructose 1,6-bisphosphate + H2O = beta-D-fructose 6-phosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:11064"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="EC" id="3.1.3.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="12">Carbohydrate biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 16">Belongs to the FBPase class 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.11" evidence="6"/>
    <dbReference type="EMBL" id="JAAAID010000373">
        <property type="protein sequence ID" value="KAG0018308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1H5"/>
    <dbReference type="OrthoDB" id="10256725at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042132">
        <property type="term" value="F:fructose 1,6-bisphosphate 1-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030388">
        <property type="term" value="P:fructose 1,6-bisphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006002">
        <property type="term" value="P:fructose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006000">
        <property type="term" value="P:fructose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005986">
        <property type="term" value="P:sucrose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00354">
        <property type="entry name" value="FBPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.190.80:FF:000001">
        <property type="entry name" value="Fructose-1,6-bisphosphatase class 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.540.10:FF:000008">
        <property type="entry name" value="Fructose-1,6-bisphosphatase, cytosolic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.540.10">
        <property type="entry name" value="Fructose-1,6-Bisphosphatase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01855">
        <property type="entry name" value="FBPase_class1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044015">
        <property type="entry name" value="FBPase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000146">
        <property type="entry name" value="FBPase_class-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033391">
        <property type="entry name" value="FBPase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028343">
        <property type="entry name" value="FBPtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020548">
        <property type="entry name" value="Fructose_bisphosphatase_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006778">
        <property type="entry name" value="PRK09293.1-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006779">
        <property type="entry name" value="PRK09293.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11556">
        <property type="entry name" value="FRUCTOSE-1,6-BISPHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11556:SF1">
        <property type="entry name" value="FRUCTOSE-BISPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00316">
        <property type="entry name" value="FBPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18913">
        <property type="entry name" value="FBPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500210">
        <property type="entry name" value="FBPtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000904">
        <property type="entry name" value="FBPtase_SBPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00115">
        <property type="entry name" value="F16BPHPHTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56655">
        <property type="entry name" value="Carbohydrate phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00124">
        <property type="entry name" value="FBPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 16" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fructose-1-6-bisphosphatase class I N-terminal" evidence="17">
        <location>
            <begin position="10"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="Fructose-1-6-bisphosphatase class 1 C-terminal" evidence="18">
        <location>
            <begin position="203"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00032973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00040159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00070480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU000508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF18913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAG0018308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="339" mass="37271" checksum="7A998D762B3B0B2E" modified="2023-09-13" version="1">MSDHTKTNLITLTRHVFQDQVENHKEASGDLTLLLTAIQLGCKFVASNVRKASLISMTGLANTSNIQGEEQKKLDVIANEIFVNALRSSNKVAIMVSEEDEEAIIVEDKNRGKYCVVFDPLDGSSNIDCGVSIGTIFGIYKVKEGSTGQISDVLRPGSEMVAAGYCTYGSCSTLVLTTGQGVNGYTLDTEIGEFILTHPDIQIPTRGKIYAVNEGNSKYWDEPCKKYFHSLKFPEDPKKSPYSARYVGSMVADVHRTMLYGGIFCYPADSKSKNGKLRILYECFPMAFLVEQAGGRASTGLKRMLDVQPQTIHSRSPIFLGSKSDVEDIEALYQAEQKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1Q6</accession>
    <name>A0A9P6T1Q6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Checkpoint protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_008198</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the HUS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000438">
        <property type="protein sequence ID" value="KAG0017513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1Q6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030896">
        <property type="term" value="C:checkpoint clamp complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044778">
        <property type="term" value="P:meiotic DNA integrity checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033314">
        <property type="term" value="P:mitotic DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031573">
        <property type="term" value="P:mitotic intra-S DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.70.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016580">
        <property type="entry name" value="HUS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007150">
        <property type="entry name" value="HUS1/Mec3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12900:SF0">
        <property type="entry name" value="CHECKPOINT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12900">
        <property type="entry name" value="MITOTIC AND DNA DAMAGE CHECKPOINT PROTEIN HUS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04005">
        <property type="entry name" value="Hus1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF011312">
        <property type="entry name" value="Cell_cycle_HUS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR011312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0017513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="227" mass="25815" checksum="3E3E0D0A3955BE5D" modified="2023-09-13" version="1">MRMTGRLADAYLSFNITSEDHLGNSRVITQNVPIVKVLTSDGASNTTVFEEPMIPTPEVHIMLPHLERLRHVMVSYKSLADYVVISANLDGEMVFTTSDGVQHQFDGTFRNNNDTGDEEEMVMTPIRYGMAEKAHVETRFTNLNHPVMKDDDEGDHPHLERLHNRPKEFASVLVKVLDLQKVLQSHYVKPSNVICSIVPNHCILFYVYMKKDAQEAALTYFIPEISL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T247</accession>
    <name>A0A9P6T247_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Arp2/3 complex 20 kDa</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ARPC4</name>
        <name evidence="9" type="ORF">BGZ80_005774</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ARPC4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000284">
        <property type="protein sequence ID" value="KAG0019467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T247"/>
    <dbReference type="OrthoDB" id="336240at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005885">
        <property type="term" value="C:Arp2/3 protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030041">
        <property type="term" value="P:actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034314">
        <property type="term" value="P:Arp2/3 complex-mediated actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1460.20:FF:000001">
        <property type="entry name" value="Actin-related protein 2/3 complex subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1460.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034666">
        <property type="entry name" value="ARPC2/4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008384">
        <property type="entry name" value="ARPC4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001206">
        <property type="entry name" value="Diacylglycerol_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045540">
        <property type="entry name" value="YegS/DAGK_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22629:SF0">
        <property type="entry name" value="ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22629">
        <property type="entry name" value="ARP2/3 COMPLEX 20 KD SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05856">
        <property type="entry name" value="ARPC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00781">
        <property type="entry name" value="DAGK_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19279">
        <property type="entry name" value="YegS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69645">
        <property type="entry name" value="Arp2/3 complex subunits"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="NAD kinase/diacylglycerol kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50146">
        <property type="entry name" value="DAGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAGKc" evidence="8">
        <location>
            <begin position="175"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00054835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00082270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0019467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="467" mass="51941" checksum="F5D28E74B902BDD7" modified="2023-09-13" version="1">MSNTLRPYLNAVRQTLTAAMCLENFSSQVSERHNKPEVEARASKEVLLNPLVISRNDKERVLIETSVNSLRVSIAIKQADEIERILAHKFTRFLMQRAENFVILRRKPIEGYDISFLITNSHTEQMYKHKLVDFIVQFMEEVDKEISEMKLSLNARARIVSESYLSKLKPTVEQKLSGIKWKVEYTQRSGHASDLAREFVQEDYTIVVAVGGDGTISQVVHGYMLADGFNKGCSIGIISTGTGGDFVRTTQTPKDPIKALDIILNNESTAVDVGHVTCSKSNAPSVQIEQHFINICSVGLSGAIIKRVESSSLAKYLSGGLVYWIYTYLTALTYRSPRVKYTLSEDTTPAKDEKQIELYIMAMANGRYFGGNMHIAPNADISDSKFDVVCLHNLSLAQVISKGSPALKSGNLMSLPPHQAFTQRDSKVTMSPVNPLDKVYVEADGEIAGILPATWEIIPNGCRMILP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2S6</accession>
    <name>A0A9P6T2S6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">mRNA 3'-end-processing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BGZ80_003644</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Component of the cleavage factor I (CF I) involved in pre-mRNA 3'-end processing.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the CPSF4/YTH1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000198">
        <property type="protein sequence ID" value="KAG0020762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2S6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031124">
        <property type="term" value="P:mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.1000.10:FF:000012">
        <property type="entry name" value="cleavage and polyadenylation specificity factor subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045348">
        <property type="entry name" value="CPSF4/Yth1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23102:SF24">
        <property type="entry name" value="CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23102">
        <property type="entry name" value="CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14608">
        <property type="entry name" value="zf-CCCH_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18345">
        <property type="entry name" value="zf_CCCH_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 11" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="9 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0677">Repeat</keyword>
    <keyword evidence="8 11" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7 10 11" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 10 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="12">
        <location>
            <begin position="41"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="12">
        <location>
            <begin position="70"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="12">
        <location>
            <begin position="98"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="12">
        <location>
            <begin position="127"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="12">
        <location>
            <begin position="156"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="10">
        <location>
            <begin position="41"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="10">
        <location>
            <begin position="70"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="10">
        <location>
            <begin position="98"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="10">
        <location>
            <begin position="127"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="10">
        <location>
            <begin position="156"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU369008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0020762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="226" mass="26272" checksum="1778F77AB53DB0A6" modified="2023-09-13" version="1" fragment="single">MAVAYSILPSEIDFQDYTFDFEEFVRNEVGLDINSAKRNGETGDNICRFFLKGHCSKGNNCQFRHIRTDPSKAVVCKHWLRGLCKKGDNCEFLHEYNLRKMPECWFYSKYGECNNGAECIYLHIDPESKIKDCPWYARGFCKHGPNCRHKHTRKVICQNYVTGWCPQGPNCPNGHPKYELPPPNWDDGQGARPIVPDRTFVERHEPSRPDNETPTFRNVEDVTCFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T377</accession>
    <name>A0A9P6T377_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">MTOR-associated protein MEAK7</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">TBC/LysM-associated domain-containing protein 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">TLD domain-containing protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BGZ80_002673</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Lysosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000167">
        <property type="protein sequence ID" value="KAG0021304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T377"/>
    <dbReference type="OrthoDB" id="26679at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006571">
        <property type="entry name" value="TLDc_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23354:SF131">
        <property type="entry name" value="MTOR-ASSOCIATED PROTEIN MEAK7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23354">
        <property type="entry name" value="NUCLEOLAR PROTEIN 7/ESTROGEN RECEPTOR COACTIVATOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07534">
        <property type="entry name" value="TLD"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TLDc"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TLDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
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            <begin position="335"/>
            <end position="536"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
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    </evidence>
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        <source>
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    </evidence>
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        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00022490"/>
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    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00039594"/>
        </source>
    </evidence>
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        <source>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
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        <source>
            <dbReference type="PROSITE" id="PS51886"/>
        </source>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="583" mass="65214" checksum="4693106A2EC90E8B" modified="2023-09-13" version="1">MGSQTSKHDTAIEACLADFSDQERTHLLELFDKIRGSQNNGSKEHTTSADDDDTIDSQHFNSYFEPLLPPTLLTCFRVTMQMHSVMHIPSEESTDSGAAGGSNIQASKSKNRRSAMTRSTSIDANSRISKYGWIMTIHRLSKTNIEEQAGLSFMLQTHDESLESFIKNVTRAVMPFWLAGEVSSWKDIPEDSTTTEFLLTRHLGPGNSGTGSDFEDIFGTHESTDDLGATTSKDKAAQDWLEAAQKRDSQGNPSTKELSRSAFVNWYQHTVEYQILFTILIQNLFLSPSTLANSETSSTPRKRIKMTTEQENKLCQKNYIAPRIKGLDVAPYFSRLLTVADFFQLRYALPTPIYNTPPPPGPSKKQGTSGSSASPDGADQISESKSTPPLRLLFSSKTSGESFSTLMQKITFQGPTLVIMKDEDGYIFGAYADQDWEQKPNFYGSDRSFLFTIQPKFRIYRPSRVNNNFQYLDYGTKTLPNGIGFGGQLRYFGLWLESDFSTGQSAAEPLCSTFQSPSLSKKQDFKLDEMEVWQVHPSTVERDEGPKRSAMDAHPDAVALLEMANRKMYSKDVRGPDVSYDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3K3</accession>
    <name>A0A9P6T3K3_9FUNG</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">BGZ80_000489</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000110">
        <property type="protein sequence ID" value="KAG0022348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="entry name" value="alpha/beta hydrolase"/>
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        <property type="entry name" value="AB_hydrolase_fold"/>
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        <property type="entry name" value="alpha/beta-Hydrolases"/>
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    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="116"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="149"/>
        </location>
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    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="194"/>
        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0022348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="300" mass="33410" checksum="EDC8666863B15626" modified="2023-09-13" version="1">MPPNKLESGETYIRYFTNVLKTSIETDHSFYPPILIAHGMHVAQKYVESNPVSALVLVSPFIPEIIKGRFWGLSRKLQLQKLLEQNVLAQDGFRETFVLPKKAVYKIDQIAKELQEKEKSKEKEHSEKEALHTKEEEADPKSKHEHEDISSSNPTTSTEASAEQEIEVLGTDSDPVWGSAEDGSTTKDSTNDGNQDPLPIMTVESEASIPSPLEQLPLAIYDSIPTSKFEPTFPILLVTSNADEIVSTADVKEHHVLSGHVDHIELENLDDGGHLIMVSDNTEWEQGIQGITAWLDSEGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T427</accession>
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        </submittedName>
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        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
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                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
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                <person name="Bonito G."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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        <property type="protein sequence ID" value="KAG0022199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0022199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="242" mass="27396" checksum="9DF49F1202E97CB8" modified="2023-09-13" version="1">MALMMGIMNIFRGLAREYPLIFSPRDINSYIRRSRNIASWSDSLCRISGRAVNPRVKQSLSATFERISTFYPGAPKDDKQLLIECALEFVIYAGIKKGCKLHGDSKIDQDEIERQYWNHCGEKSPAIEDDDQNKDILVISHTANGCIESQDINIHGASRQMYSPDNSLSDFCVPSDEDDEMEYNNNHWSLSDDVNPYSMDLGEDPVGTRQIPSHISRADSSVINFSDLVFSSDSTFTSPMYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T4A0</accession>
    <name>A0A9P6T4A0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PA14 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_007562</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
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            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
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            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000039">
        <property type="protein sequence ID" value="KAG0023870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T4A0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.182.10">
        <property type="entry name" value="Toxin - Anthrax Protective Antigen,domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037524">
        <property type="entry name" value="PA14/GLEYA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011658">
        <property type="entry name" value="PA14_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07691">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00758">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56988">
        <property type="entry name" value="Anthrax protective antigen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51820">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PA14" evidence="3">
        <location>
            <begin position="452"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="50"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="159"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="259"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
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        </location>
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    <feature type="region of interest" description="Disordered" evidence="2">
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            <end position="815"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="700"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="13"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="57"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="172"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="297"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="649"/>
            <end position="663"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0023870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="945" mass="104323" checksum="C65DFBF0D3756480" modified="2023-09-13" version="1">MSSRPINMLRPKASSASISSNTSISSNTTAQTFMTSFSFSTITGSHDRSVTQEDLLSSSAGSYSSTGAPAHYGENYDEGREEKEVDVESLDIAITTPTDNIHINPFDYQHDPVLQPQSSTWSKGHNKSFSQQSAVTIKGRQFGGSSSNMTAVLLPSPLTSSSSTAFHQQVQRVDEETAKDTEDTEGAAEDMMFASPDYRKSVALSDHSDLALDSSSPSGEASSGNTSEMAQYTNLLRDATTIIEQQHIQDHITSMPLEDHESEGAGIDSNNVHDSGYLRHNAEPSIGSSCGRDMRSSSRISDAGSTAEKTSVSSGRSTLTRSQSRRFSAPGHPGSSHTSLISIANASEASQASTESTASQGPVAFLAPVSGSRGPQSFVDNDEPSGVNNRMYLPGLYSNNSHLAEGTSFKRAFHPLQHHTTMQAYPEKESVAPEPSVITSSAAQHQPHLHRDYRPGVVFEYYEGEWDWLPNFDEMRPDNVGIVGNFMIDDTTEQDLFRARYSHQTRRQFKESGNFAVRFTTYIDITQDGVYSFWLSSNDGSVLYVSNRLVVENDGMHYATEAEGRIMLQAGKHAMTVEFFHKNGKMLEGFRSTGPSLIVSYRAPGPVWSFGLKPGPKKIIKSNNLFFDHGDVRLKNLLREFGVDDDSSMENNSHLSSNITRNTGPGVDFWPPAANDNQQNSRRSRYRVASGDMGHLQPSARELNVQMENAKATIRDLEQIIRDQADSHKKKMAEMYSMLQDTQAQVDRMVAGLKKATLFETPRTTITPNFHLGENHPSTWRNTVMSVYVDAQEDYPLDNDLDASGQGDSGKENAVDSDDILAKHIADVEKLKQLYFFSMALSVKMNSEMMGKKTAEYTSTSVQKLYEDCAINSKVPVEGWPGLDLSHKDDDDSDDDDERELLKYSMLGGYYIRPRAMGGLDYRRYSKATRILDDCPASYSDTSSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MC03</accession>
    <name>A0A9P6MC03_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_009191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010005292">
        <property type="protein sequence ID" value="KAF9991362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MC03"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9991362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="78" mass="8989" checksum="C1BCCB7149C52430" modified="2023-09-13" version="1" fragment="single">GQGRDHNLVLHSVERCTRRYSREGRVVDGAVWSLARQGLLHSHKARPIFGGERRSYTRNALEGSLRFFVLINLDQKPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MCF5</accession>
    <name>A0A9P6MCF5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">HAT C-terminal dimerisation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_008680</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004793">
        <property type="protein sequence ID" value="KAF9992151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MCF5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008906">
        <property type="entry name" value="HATC_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052035">
        <property type="entry name" value="ZnF_BED_domain_contain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46481:SF10">
        <property type="entry name" value="ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46481">
        <property type="entry name" value="ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05699">
        <property type="entry name" value="Dimer_Tnp_hAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="HAT C-terminal dimerisation" evidence="6">
        <location>
            <begin position="108"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF05699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9992151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="185" mass="21327" checksum="C5BFDF159EB13703" modified="2023-09-13" version="1" fragment="single">MINYLEDFIAKESDSMLNKAADQGLQKLLSYYSKTDSTPVYAVATAMDPRMRFDWWEANEWGTYIQLSKDMVKNVWESDYKGKEGPIELDAEVAKQMKLFGIKTKAGELEEYIREGSSLVPCKNEPPELMYWRSQTERLPNLANMARDYLAIPVTSTPSERCFSQAKFVLPPERNSLHPNTIQRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ME55</accession>
    <name>A0A9P6ME55_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="5">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">PPIL2</name>
        <name evidence="10" type="ORF">BGZ80_007774</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the NOSIP family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cyclophilin-type PPIase family. PPIL2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="5"/>
    <dbReference type="EMBL" id="JAAAID010004032">
        <property type="protein sequence ID" value="KAF9994591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ME55"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16663">
        <property type="entry name" value="RING-Ubox_PPIL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000079">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016818">
        <property type="entry name" value="NOSIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026951">
        <property type="entry name" value="PPIL2_U-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003613">
        <property type="entry name" value="Ubox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031790">
        <property type="entry name" value="Znf-NOSIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13063">
        <property type="entry name" value="ENOS INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13063:SF10">
        <property type="entry name" value="NITRIC OXIDE SYNTHASE-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15906">
        <property type="entry name" value="zf-NOSIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00504">
        <property type="entry name" value="Ubox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51698">
        <property type="entry name" value="U_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="U-box" evidence="9">
        <location>
            <begin position="16"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9994591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="140" mass="15958" checksum="5B1169EAEE54B81C" modified="2023-09-13" version="1" fragment="single">MTFGGAGGRKKTQIFRRLPFDCCSLSLQPFEHPVCTEDGIIFDLVNIVPYLKKFGTNPATGEKLDAKSLIKLNFFKNANDEYHCPISLRVFNENTHIVAIKPSGNVFAYEAVERLNIKAKFWKDLMTDEPFTRKDIITIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MEW6</accession>
    <name>A0A9P6MEW6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Lytic polysaccharide monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007402</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003781">
        <property type="protein sequence ID" value="KAF9995864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MEW6"/>
    <dbReference type="OrthoDB" id="2342176at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36182">
        <property type="entry name" value="PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G10930)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36182:SF1">
        <property type="entry name" value="PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G10930)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040205123" description="Lytic polysaccharide monooxygenase" evidence="1">
        <location>
            <begin position="24"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9995864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="238" mass="26022" checksum="5DEE99D427D00C3C" modified="2023-09-13" version="1">MTAFRNWTALFAVVALFIQSTVAHMALLYPMPRGGVLDKKQFDGKVHAFIGFESERTMPCNGYNKPGPVTHLKAGETINVRFWGPALPEKYFNTLPPIGSASSQYNQARHDGGTCQFSLSYDNGKTFHLIGQYTKSCPDFYYDWPVKIPEDAPSCEKSDQCLFVWSWTAANVDQFYINCADVTIAGKSGGKLNKKGITIDDVKGYKTAVAPGDAAGDKRGKGPIASQVKANKNGAFSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MFV9</accession>
    <name>A0A9P6MFV9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Carrier domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_007055</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the NRP synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003549">
        <property type="protein sequence ID" value="KAF9997207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MFV9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043041">
        <property type="term" value="P:amino acid activation for nonribosomal peptide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12117">
        <property type="entry name" value="A_NRPS_Srf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.30:FF:000010">
        <property type="entry name" value="Enterobactin synthetase component F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12780:FF:000012">
        <property type="entry name" value="Non-ribosomal peptide synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.980:FF:000001">
        <property type="entry name" value="Non-ribosomal peptide synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.38.10:FF:000001">
        <property type="entry name" value="Non-ribosomal peptide synthetase PvdI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1200.10:FF:000005">
        <property type="entry name" value="Nonribosomal peptide synthetase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.980">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.38.10">
        <property type="entry name" value="Luciferase, Domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF1">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="540"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="671"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9997207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="671" mass="74777" checksum="A5E2171522B87AE2" modified="2023-09-13" version="1" fragment="single">MPVRHLQILPAVEREMLTQSWNTTDTAYPDNMCVHKLLENQVDQTPDTIAVVYENQTMTYRELNAKANHLAIQFRELGIQPGGFIATLLERSFELIVVQIAALKIGAAYVPIDPKAPIDRQSFIINDCEAQLLITDKNIKAPEEFHSITHRLDNIYQDEIDLMAHDVDFNPTCSSLDTAYVMYTSGSTGTPKGVIIPHRAIARLTINNSYIDIGSDDHVAFAANPAFDASTFEIWAPLLNGGRVVIIDTDSFTDSRRLSEIIDRHKVTTMFLTTVLFNQFVSSIGSSLAKLKNLLCGGEQENLESFNTLLQHGGPKHLIHCYGPTESTTFATTYEVKKVDVQQNRLPIGRPISNTKAYVLDERCQPVPLGVVGELYLGGDGVAKGYLNRPELTKERFVPDPFSTKADSRMYRTGDLVRHLPDGNLVFVSRNDHQVKIRGFRIELGEIETRLLEHPMVRDATVLALGEGSGKRLVAYFVAGNSNELIHTLREHLVARLPEYMIPTAFVRLDALPLTRNGKLDRRALPEPNSDAFAIQGYEAPHGEIESSLALIWSELLKIDRVGRHDNFFMLGGHSLLAVQMIERLRRVGLEFSVRALFETPTLIALAQTLNKFQNTAAAPANQITTDTVLITPEMLPLIDLTQHDIDTIVDQVPGGVSNIQDIYALSPLQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MG91</accession>
    <name>A0A9P6MG91_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006864</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003418">
        <property type="protein sequence ID" value="KAF9998081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MG91"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="224"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="100"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="249"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="275"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9998081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="362" mass="39160" checksum="756B147504964AB3" modified="2023-09-13" version="1" fragment="single">DIVSVNENFRDVAALINSLNSEHTLAEWDSALRQPFEHLTSYDEWLQRIDPQSKFCKDYRSQLNGVIHKIKMATDANPQSHNMFQRLSIVARGVVRRRSSAQTLSSGSSAPQTPTTPNTPSSIYSTDSSSIPSPIVDKDLSCQSAESNSSVSLPMPETVRDLAVTDHAMATDAVMESASSPDVRNNDQKGPKEKELPAISTTADSDMKMPSTLIADTFLTPVHPARQPQYHSSTSSGLGNSRALAMGTSPSMVSSSASSVYSKSSSSAEALQDKSTASTSSSLSKQTFLAEKENRKTTLRIGTSVAIKAKAESLQPPTYATKTTVENLRKIPPIKNVTVKKPPVKSLISFWEQVKVSNPLDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MGK0</accession>
    <name>A0A9P6MGK0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_006633</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003282">
        <property type="protein sequence ID" value="KAF9999145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MGK0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF309">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14510)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="20"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9999145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="183" mass="19407" checksum="96418E05FD5F9B89" modified="2023-09-13" version="1" fragment="single">MSDIKSSSIHHTPNPSNPKIIITGAGLGGLTLAILLEKASIDYEILERATVLKPLGSATGLAPNVMPLLEQLGLLDELKKISLECMSGSIYKDLPNGESLELLNMTDASALRGLSGYASIIMSRPDLHALLLSHVPSHKIHLGKRVLSMSQSDDNGVLVRTNDGSTHLCDILVGCDGAYSGVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MIM2</accession>
    <name>A0A9P6MIM2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005918</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002915">
        <property type="protein sequence ID" value="KAG0002739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MIM2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101447">
        <property type="entry name" value="Formin homology 2 domain (FH2 domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="296"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="353"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="412"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="65"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="175"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="303"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="366"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="412"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="422"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="437"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0002739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="465" mass="51124" checksum="5C67E76BA5CE0AF2" modified="2023-09-13" version="1" fragment="single">LPPPPPPPPPPVTLSRSAPSPTSTLLKNQKNDPSVLWDQHLAFLERLEAGSRAGDSQLSLKPHSRFGSRFGSRSGNPELDSSISKTNNNNNNDSYNHDQKLAQHLSTRRASLPVTLSSQATWMGSQSWPRPYPSRSRSLTRSRASSITPYVPRSSRLFREAFKKAMTVRSPVLTSTSSGMGTLSDLSSSSSSSSSSSSMSPSALQPVQTDTKLGERNLEVRKGQEDMWGTRSCLTEMLGDDRSRILISDIDQVDPINDQLSTEVEVKVKREPLEDDMDGLLLYDDTSSDALLTGTLKSETRNNRQQSVSANRSASVLKENGKEEEDTTCHMPPPSSTPVLAASVVGSKMCSTSRVSSLEDTPSSPPSMSLSPSCSQPSQSFIQEHVTAHDISLMTASFGALTPQEIQSRFYAQREQQQQQKRWQKSRRLSRRKAITKNMNNQQQQSLSAPNNANTAAVEEEEEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MIU0</accession>
    <name>A0A9P6MIU0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_005912</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002910">
        <property type="protein sequence ID" value="KAG0002813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MIU0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040048">
        <property type="entry name" value="ZNF277"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13267">
        <property type="entry name" value="ZINC FINGER PROTEIN 277"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13267:SF3">
        <property type="entry name" value="ZINC FINGER PROTEIN 277"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="27"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="56"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0002813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="284" mass="31325" checksum="B4B55107D8B04464" modified="2023-09-13" version="1" fragment="single">MSNEGEWTTVTSKHSTGHKPQRPLSTVGVGASSSASSSKADPRAATDKSSGSATKAGHHYPHHHKKPPRKESSSSPANAAVSGSSTQKDSSIKTGNKQTSRSRSSSISSDSDSSQSDDPSSLGSGRPPYHAVIMIHCSFHSCDLTEPLTDSTSLVAHLKEAHKIAFKNIHHMFILLERYLNHWAEEIEAKGIENVAVKENVDDDYYTIDPTVSAADRTLRDEIQREKLNEILKVQEKERNEDAKLKRKTILFKHMFAEHNFNIGLPDNLVNVNEFLDMLEAKLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MJ17</accession>
    <name>A0A9P6MJ17_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_005788</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002848">
        <property type="protein sequence ID" value="KAG0003482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MJ17"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040345758" description="Secreted protein" evidence="2">
        <location>
            <begin position="23"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="21"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0003482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="58" mass="6274" checksum="68FADD47A54A0087" modified="2023-09-13" version="1" fragment="single">MRSSIAITIFAMLLIGITRTHSAPTSPTTPTTPEPTERCGYVCKDGKIIDTNPGDKMH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MLJ1</accession>
    <name>A0A9P6MLJ1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Pre-mRNA-splicing factor SYF2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_004934</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Involved in pre-mRNA splicing.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">May be part of a spliceosome complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the SYF2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002469">
        <property type="protein sequence ID" value="KAG0007214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MLJ1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013260">
        <property type="entry name" value="mRNA_splic_SYF2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13264">
        <property type="entry name" value="GCIP-INTERACTING PROTEIN P29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13264:SF5">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR SYF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08231">
        <property type="entry name" value="SYF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 8" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0747">Spliceosome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="26"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="72"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="127"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU367148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0007214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="331" mass="38444" checksum="B1C1ABFB58B0EA5A" modified="2023-09-13" version="1" fragment="single">QNETKEEIAEETVKVKTTRTTKTKKTTVTVTTTVIPQDEQVKEVEEKLEKPDSEMKAEEEQQNDSEMTTPAIEERSADQDQEMKETDASQPEEKTSSASLTMAERMEKLKGLRQKMNASKQANRADLMTEHQKSKINKREEAKKERLREEAEKLIAKRDAEEAGEDYERSQFWNYSAESVEKWNEKQEAKRIRMDNKFTDWDQVNHKKYLKQVGELKPNLAAYNAKKEAAMHTNEDGELVVASDSGFYRDANSVAFLSDDKPDTLAVDRLAADVAKQIDARTRFSKRRAQRDDEDVNYINDANRRFNQKISRFYDKYTKDIRDDFERGTAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MM34</accession>
    <name>A0A9P6MM34_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004440</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002265">
        <property type="protein sequence ID" value="KAG0007619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MM34"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="226"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="356"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="173"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="357"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="388"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="405"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="435"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="446"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="511"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="531"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0007619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="596" mass="64585" checksum="C6A2E8CC8367A58C" modified="2023-09-13" version="1" fragment="single">MDVELVDASPYHDVKNVQMIASPLFNVPVPIPPPYDTHPLPDDFKQRRYHDFSLEHRIVQEYQRIMAEEAAVMEAKESAYRLYSEERQARLKQERINRARKIAPGFLDNEDRRILTPTLATSQVKDASVANEGSKAFSEKNNHIDYSEFEFSDGPSGEVTGAVKESIEDEQQLHQQQQQQQQADSNYTSSSQDYHQEAGDVVEEEEIIIQAVPLSTITGMLRDSCLDEDVSSPGPRAWTERDAASEKTSVPSFNATARLDFREFEQGLGPPDPWDTPVDDLTALKDVISQQMGHSSSSQSQQVQQQQQQYQQHQQQQQTSYLYQQQTQQQQQQQQQQPQVSNSFQQQNADQQMLNQYPYNSTPNRTGFNSSPLPVASYVPQPKLTGIAQQQQALQHHQQQHQQQRHSTGSTIGSPLSNTGMTAAQQQARFGAASPSPPPLPPPPRALTSSPGLGTGTPTSTVTVGGGGAAGGLNRPPVPARPGRPSDQADLATSGGGSADHVTTMERTMTPPRPPLPPPPPGSQGAGGNGIVSSSATSSSIPVSSGAATSVGGQLPSSLGVGGPTSATASRPALKPRPPKEHEILQGIIGTKKTPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MN20</accession>
    <name>A0A9P6MN20_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">DNA replication complex GINS protein PSF1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">GINS1</name>
        <name evidence="10" type="ORF">BGZ80_004090</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the GINS complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the GINS1/PSF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002125">
        <property type="protein sequence ID" value="KAG0007907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MN20"/>
    <dbReference type="OrthoDB" id="10252587at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000811">
        <property type="term" value="C:GINS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902983">
        <property type="term" value="P:DNA strand elongation involved in mitotic DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11710">
        <property type="entry name" value="GINS_A_psf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21696">
        <property type="entry name" value="GINS_B_Psf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021151">
        <property type="entry name" value="GINS_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036224">
        <property type="entry name" value="GINS_bundle-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005339">
        <property type="entry name" value="GINS_Psf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056783">
        <property type="entry name" value="PSF1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12914:SF2">
        <property type="entry name" value="DNA REPLICATION COMPLEX GINS PROTEIN PSF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12914">
        <property type="entry name" value="PARTNER OF SLD5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24997">
        <property type="entry name" value="PSF1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05916">
        <property type="entry name" value="Sld5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158573">
        <property type="entry name" value="GINS helical bundle-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0235">DNA replication</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GINS subunit" evidence="8">
        <location>
            <begin position="139"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="DNA replication complex GINS protein PSF1 C-terminal" evidence="9">
        <location>
            <begin position="229"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="62"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="84"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU368085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF05916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF24997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0007907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="280" mass="32548" checksum="B56EF97A8585CE99" modified="2023-09-13" version="1">MYGEEASKLARETKRTIDHFPPYNDSLVRSITREIRHLYETCQALINDYNLQKERIESEIKQQWHQQHGTSTSTIQGSTELTSQQQQQQQQQQQRDPNYTTLEMLDELALPSSSSSATLYSNVSLANLQDQVERALQPVKEVFWTKYLVHSTPLQRNKRILMAYHHQRIEKIKELSWAHNTLPESSRRLLSPDEIIFFNEYEKHCRNKYTSDPALGEIDLSLGMIYPPKEVFITVRVIKDCGDIVTESGATLSLKKNSEHFVKRSDVERLITQGYLLHVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MN25</accession>
    <name>A0A9P6MN25_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_003945</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002079">
        <property type="protein sequence ID" value="KAG0008019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MN25"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001210">
        <property type="entry name" value="Ribosomal_eS17"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10732">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10732:SF0">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00833">
        <property type="entry name" value="Ribosomal_S17e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0008019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="66" mass="7545" checksum="62AB05A2594F10CB" modified="2023-09-13" version="1" fragment="single">EEERERKDNYIPEFSALDTSSIEIDTETQNLLKSLNFEDLAGVTAVEVKQAPIETRKPRGPRPERS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MND1</accession>
    <name>A0A9P6MND1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_004439</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002264">
        <property type="protein sequence ID" value="KAG0007621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MND1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF309">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14510)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="19"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0007621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="285" mass="30934" checksum="E94F4B632BA926D0" modified="2023-09-13" version="1" fragment="single">MSDLNNPSIHYTPNPSNPKIIIAGAGLGGLTLAILLEKASIDYEILERATALKPLGSATGLAPNLMPLLEQLGLLDELKKISLECMSGGIYKDSPNGESLDFLSKTDISALKEFSGYATVIMSRPDLHALLLSHVPSHKIILGSVSCLYHREVKMAYSSGLEGCLPKSDGEDMKVCHMSILGTTNSIDPSIVPLSKDGFSRCDTVLGYKNPHSSDAFKNSDWGSESSGSIQEDWRAFKLPLGPDNPYITIGDLINLTENDNVTKVMLEEKLYTTWHHGRTVLMGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNQ8</accession>
    <name>A0A9P6MNQ8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphoribosylaminoimidazole-succinocarboxamide synthase</fullName>
            <ecNumber evidence="3">6.3.2.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">SAICAR synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ADE1_1</name>
        <name evidence="11" type="ORF">BGZ80_003297</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SAICAR synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.6" evidence="3"/>
    <dbReference type="EMBL" id="JAAAID010001865">
        <property type="protein sequence ID" value="KAG0008566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNQ8"/>
    <dbReference type="OrthoDB" id="9991235at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004639">
        <property type="term" value="F:phosphoribosylaminoimidazolesuccinocarboxamide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01414">
        <property type="entry name" value="SAICAR_synt_Sc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000392">
        <property type="entry name" value="Phosphoribosylaminoimidazole-succinocarboxamide synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.20:FF:000015">
        <property type="entry name" value="Phosphoribosylaminoimidazole-succinocarboxamide synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00137">
        <property type="entry name" value="SAICAR_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028923">
        <property type="entry name" value="SAICAR_synt/ADE2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001636">
        <property type="entry name" value="SAICAR_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018236">
        <property type="entry name" value="SAICAR_synthetase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF010568">
        <property type="entry name" value="PRK13961.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00081">
        <property type="entry name" value="purC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43700">
        <property type="entry name" value="PHOSPHORIBOSYLAMINOIMIDAZOLE-SUCCINOCARBOXAMIDE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43700:SF1">
        <property type="entry name" value="PHOSPHORIBOSYLAMINOIMIDAZOLE-SUCCINOCARBOXAMIDE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01259">
        <property type="entry name" value="SAICAR_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56104">
        <property type="entry name" value="SAICAR synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01057">
        <property type="entry name" value="SAICAR_SYNTHETASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01058">
        <property type="entry name" value="SAICAR_SYNTHETASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAICAR synthetase/ADE2 N-terminal" evidence="10">
        <location>
            <begin position="15"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0008566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="298" mass="33380" checksum="4EFA0FE1D1E08C14" modified="2023-09-13" version="1">MSAIVTTNCPDLELIARGKVRDLYRVDANSLLFVATDRISAFDVIMQNGITNKGKLLTEISIFWFSFLKDVLPNHLITANFDEMPAKVKQYRDQLEGRSMLVKSLRVLPIESIVRGYITGSAWSEYKKKGTVCDIALPAGMQESQAFPEPLWTPSTKAEIGDHDENIHPSKAAAIIGEKHAAEMARVSVELYTKARDYALERGIIIADTKFEFGVDENDTLYLIDEVLTPDSSRFWPAATYKVGAGQDSFDKQYLRNYLESIGFDKSTGITLPDDVVKNTMSKYQEAYKLLTGKDAQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNW6</accession>
    <name>A0A9P6MNW6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcription factor spt8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">SPT8</name>
        <name evidence="4" type="ORF">BGZ80_003192</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001830">
        <property type="protein sequence ID" value="KAG0008668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNW6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057544">
        <property type="entry name" value="Beta-prop_SPT8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879:SF9">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23798">
        <property type="entry name" value="Beta-prop_SPT8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Transcription factor spt8 beta-propeller" evidence="3">
        <location>
            <begin position="141"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="188"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="Transcription factor spt8 beta-propeller" evidence="3">
        <location>
            <begin position="253"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="15"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0008668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="419" mass="45806" checksum="A656E75D72947D0E" modified="2023-09-13" version="1">MDSEHESEDEFNQNDDNRSDDGSERGGDAEDDSGVNQTPATGPEESATADRTHVPLKLQPNILDCKTFDIMPCAGILTSYWENEEQPNKLASAVGENGVPIAGPSSSSGMANSTDMDLDTNVVKREGSAEPGMAHANLRASSPEESKMSAVYSLDCHSEAVFAISGLESGSINLWTPRHEEGTCHHVFRQHTAPVSALKLTPDEQGFISGSWDHSVLQWDLNYGAIVRTYNGHGSQISSLSFQPTEMPTPTMDLSSPTANCSNDAVLMSTSVDGTICLWDRRDPTQIPRKFMPPEKVPPWCLSACWSADVDEWDFAEGKFIQSIKMPANSGPVSFVKCLPNNKHLICASQDNIRLWNTTELESKSSLRPFQIIAGHHGGLISNIHIDPTCKYMITTSGNREWEGPSTNGCLFYDIQPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MP58</accession>
    <name>A0A9P6MP58_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_003741</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002002">
        <property type="protein sequence ID" value="KAG0008201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MP58"/>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016460">
        <property type="term" value="C:myosin II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000001">
        <property type="entry name" value="Calmodulin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050230">
        <property type="entry name" value="CALM/Myosin/TropC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048:SF48">
        <property type="entry name" value="CENTRIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048">
        <property type="entry name" value="MYOSIN LIGHT CHAIN 1, 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="30"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="185"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="221"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="84"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="85"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="120"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="137"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0008201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="255" mass="28538" checksum="CD7D21FC0B1B9239" modified="2023-09-13" version="1">MVTHKKTTPSFSSSVLGISGGTDLSEVSPAYYQELQDTFQLFDTEHKGVLSIKKLRLAMRTLGFEASIDDIQEIIQEMPELSVHMTKKKKQQGRKAKNKGKESGSSTLDKESTGARRSSRVAAAASKTSSKPKYADSDVEVSSGDDDAYEDEETGADMDDEKDDMELYFTMEDFIIIMTPNEEQHGQDEISRVFQLFDTQSKGSIRFEDLRRVATELGIPMKDEELREMIEEADRDGDGAVTEQEFGKIVKKTGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MP59</accession>
    <name>A0A9P6MP59_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Chromatin remodelling complex atpase chain isw1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BGZ80_003319</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001870">
        <property type="protein sequence ID" value="KAG0008550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MP59"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140658">
        <property type="term" value="F:ATP-dependent chromatin remodeler activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031491">
        <property type="term" value="F:nucleosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034728">
        <property type="term" value="P:nucleosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd17997">
        <property type="entry name" value="DEXHc_SMARCA1_SMARCA5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000082">
        <property type="entry name" value="ISWI chromatin remodeling complex ATPase ISW1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10810:FF:000002">
        <property type="entry name" value="ISWI chromatin-remodeling complex ATPase CHR11 isoform A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1190">
        <property type="entry name" value="iswi atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.30">
        <property type="entry name" value="ISWI, HAND domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044754">
        <property type="entry name" value="Isw1/2_DEXHc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015194">
        <property type="entry name" value="ISWI_HAND-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036306">
        <property type="entry name" value="ISWI_HAND-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015195">
        <property type="entry name" value="SLIDE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45623">
        <property type="entry name" value="CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45623:SF49">
        <property type="entry name" value="SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A MEMBER 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09110">
        <property type="entry name" value="HAND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09111">
        <property type="entry name" value="SLIDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101224">
        <property type="entry name" value="HAND domain of the nucleosome remodeling ATPase ISWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0804">Transcription</keyword>
    <keyword evidence="9" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="13">
        <location>
            <begin position="174"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="14">
        <location>
            <begin position="471"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="15">
        <location>
            <begin position="832"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="108"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1010"/>
            <end position="1078"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="130"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1010"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1025"/>
            <end position="1046"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0008550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="18">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1078" mass="124372" checksum="83C41D5B3E08F591" modified="2023-09-13" version="1">MNREEVVDHVSEDETMHSSDEKHEKLSKKELEKIQKEERRIQREQDRALIQQQKETFERDIIEMDKAKLVDTSNRISYLLGQTELFKHFIDLKKAKDPEFAKLLKERGEEQKEKIKAPKGSRVGRKTEKEEDQELLNDEENENDSSSFVFTESPAYIKNGTLRDYQIQGLNWMVSLYKNGINGILADEMGLGKTLQTISFLGYLKHIEGVAGPHLVIVPKSTLHNWKSEFSKWLPDSDVFLLHANKDERADMIQTRLLTQKFDVCLTSYDICLLEKTHLKKFAWQYIVIDEAHRIKNENSQLSQIIRAFNSKNRLLITGTPLQNNLHELWALLNFLLPDVFSSSEDFDAWFEKQGGDQDMVVQQLHKVLRPFLLRRIKSDVEKSLLPKKEINLYVGLTPMQRKWYQRILEKDIDAVNGAGSNKREGKTRLLNIVMQLRKCCNHPYLFDGAEPGPPYTTDQHIIDNAGKMVVLDKLLKRMKEQGSRVLLFSQMSRVLDILEDYCVFRGYEYCRIDGQTNHEDRVTAIDEYNKPDSSKFIFLLTTRAGGLGINLVTADIVVLYDSDWNPQVDLQAQDRAHRIGQKKQVYVFRFVTENGIEEKVLERAAQKLRLDQLVIQQGRMTQQQKTANKDELLTMIQHGAADVFKSTTDNLSYDPDIEQILRRGEEKTAELNQKYSSLGIEDLAKFTNAEGSAYDWQGEDWSNKRKADGSLLWITPAKRERKANYAVDDYYRDALRVAPKAPTTKAPRPPKALNIQDFQFYPSRLHELQEKEILYYRKSIGYRVPKAVGPEAANMTEEELEEQQQQEQALIDTAEPLTEEETTEKEDLMQAGFENWSKRDFISYYKACEKFGRSNLSEIANEIEGKTLQEVKAYSKVFWKRYSEIADHERIIAAIEKGESKIQRQSDIQDQLSAVIHRHRVPLQQLKIAYNQTKTKNYTEEEDRFLIVLLERLGYGTDDVYDRIRDEIRKSPIFRFDWFLKSRTPLELQRRCAYLIKCLISDDKADEPVKAVKKEDAPAKKSKAAATSSSRASPASSLKASPAVSRKGSPAVSGKASPVPNHKASPASTSSRSSRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPM5</accession>
    <name>A0A9P6MPM5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_002948</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001753">
        <property type="protein sequence ID" value="KAG0008889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPM5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052980">
        <property type="entry name" value="Crinkler_effector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33129:SF1">
        <property type="entry name" value="ATP-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33129">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0008889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="223" mass="25525" checksum="3EF5FAA29FB36400" modified="2023-09-13" version="1" fragment="single">MCTLVGTKDLYIREEYRELYDRIKSQFTLPAKSLRQNRLILTGTPGIGKSAFLVYFTIRLLVESDENDPPIIVFHEKESLTCYVYGGTSILLRGNISDFRDLLSEPETWYLVDSSKSPVLDRAKTVFSASPKTLKGRFDGVAKEVSKYYHMSPWTQNELETCRSKVKFFNDVDYNFMERLYLRMGGVPRYVLQTPADILNNDKNAVEAAEKAACSRVDEAIET</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPM8</accession>
    <name>A0A9P6MPM8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_002829</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001718">
        <property type="protein sequence ID" value="KAG0009014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPM8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0009014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="355" mass="40819" checksum="5C22F37970FB6567" modified="2023-09-13" version="1">MSTDLATSQYPEATKRVDVVFSQPTITMRWIESTTECRHMEALFLLVDDARDAHITQLMAAFPHLTDKNRVVRFANVKLDQENRRPRPKQLFRVETRFTFMGNTSAKFNHRFLTVPKSQAKRDFNNRDEDHLYTELKEGDEPERCFASAEGGLVFVKWQADEKGHRFFRPTPGVFVGLDLTAPPVIEFLGQKAPEMRPIGSTRPRNAFKVQIHLRKSDEDQLGHVTNSRYVGLLHDVLTFGLRTGYYSNGSGEDETETDLPVVPSYNMTTSQDVAVPAGSRFYKRGKIMELYVGYERELKVKPETYVWSWVEPTKIQDAYDVIRFEICSTENGQEQVVSLCRAIIKENTHQRASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPT7</accession>
    <name>A0A9P6MPT7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Septum-promoting GTP-binding protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">SPG1</name>
        <name evidence="2" type="ORF">BGZ80_002689</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001673">
        <property type="protein sequence ID" value="KAG0009152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPT7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47978">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0009152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="124" mass="14161" checksum="F9E5A0C305987E15" modified="2023-09-13" version="1">MLPLVCNDAVAILFMFDLSRKSTLNSIKEWYRQARGFNKTAIPFLVGTKYDYFSTFSKEEQEEVTKQARKFARAMKAPLIFCSTAHSINVQKIFKIVLSKAFDLKCTIPEISESGAPILEYATY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQ92</accession>
    <name>A0A9P6MQ92_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_002337</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001572">
        <property type="protein sequence ID" value="KAG0009495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQ92"/>
    <dbReference type="OrthoDB" id="2391627at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006122">
        <property type="term" value="P:mitochondrial electron transport, ubiquinol to cytochrome c"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019182">
        <property type="entry name" value="Cytochrome_b-c1_su10_fun"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28254">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28254:SF1">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT 10, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09796">
        <property type="entry name" value="QCR10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0009495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="73" mass="7834" checksum="B0CE6777918DFE47" modified="2023-09-13" version="1">MAGPRIISHSVRVLGANPENVSRWAGSAVRFGVATGAGVLFIAECLPPAKTDLFCKLPIIGSYWKAYEAKDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-10-08" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQL0</accession>
    <name>A0A9P6MQL0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">SMP-LTD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_002187</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001531">
        <property type="protein sequence ID" value="KAG0009661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032865">
        <property type="term" value="C:ERMES complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990456">
        <property type="term" value="P:mitochondrion-endoplasmic reticulum membrane tethering"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015914">
        <property type="term" value="P:phospholipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21675">
        <property type="entry name" value="SMP_TEX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031468">
        <property type="entry name" value="SMP_LBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13466:SF19">
        <property type="entry name" value="NUCLEUS-VACUOLE JUNCTION PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13466">
        <property type="entry name" value="TEX2 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51847">
        <property type="entry name" value="SMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="7" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SMP-LTD" evidence="10">
        <location>
            <begin position="313"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="108"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="520"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="608"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="712"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="800"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="917"/>
            <end position="960"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="981"/>
            <end position="1022"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1047"/>
            <end position="1121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1137"/>
            <end position="1165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1211"/>
            <end position="1235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1462"/>
            <end position="1755"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="108"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="136"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="548"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="731"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="835"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="981"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1004"/>
            <end position="1013"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1048"/>
            <end position="1061"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1090"/>
            <end position="1100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1108"/>
            <end position="1121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1217"/>
            <end position="1227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1478"/>
            <end position="1495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1566"/>
            <end position="1582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1592"/>
            <end position="1605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="1609"/>
            <end position="1622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1649"/>
            <end position="1662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1673"/>
            <end position="1689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1706"/>
            <end position="1719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1720"/>
            <end position="1731"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1745"/>
            <end position="1755"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0009661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1755" mass="193161" checksum="1B172F19080A6ECA" modified="2023-09-13" version="1">MSFFLGFLCGLLIIPSSILIGLYYFFNYSGSFAKKRQQELEDDRRAELELWSELEDSARYASYLSSTRSQGSNGVSGLAAGLEYLDARYQFAGWISVKRVPDVDHRVIEPSLKKDSKKNSSKNGQAKGSGSNMMDGGYGRGVGGSIGAGTTQDPRSTYLDTQNLHLALPPSLQARFKDSKYCVVRGTVMFVYENEKMEECFGVITLANYEVSVPGKLSDGDMFAKRHPLWLKYQHIHHSSQGKSETITNPAKDYYLSMVSCVDKEDLYFTLIRCTKLRPGSQSFLREIPKRDSTQFDKSAMNTLIRSIHSNEHQFHMAWLNAMIGRIFLGVYKTPKVKDAIFEKLEDKLSRIRLPNFINHLRMKSVYLGDGVPLITRPKLLALKPNGDMIMDLNLLYQGGFRAEIEAEAVVAVTKKIQPVISLVLVVTLDRLEGRLQAWIKPPPSNRIWYGFYHVPQVEMKIEPVVSDKHIKSNLIIKAIENKLMEAITETFVLPNMDDMPFAETDGMGGIFGEEISPPSSEPIQPAVRQHGSKLQPNGRHIPGPRSATFSLGDGTSSPRSAIEIPSDLPRRNESLPSGIYRMPAASRSYGSLGEEIMMYDSHTSIATLDDDPMRSGTPRVGQTSDGSGVKVLPVPGGRGIKVVNEQGSNGSRLVNRIYHSNTGEPIRGRRGSLDPNVSLSYSTATSMGNNYNESLFSAMDEARKMEKHLSPYGISEYDPMSGNSKKKSKSKSDKNDGDHISVHSKDSGDSGSINTEHTGQSSTFFAYSNSSHSTFDTNSVAHSGKSDKFSLSRMFHGLRKKHTKGANSGSSIQQSIEESEAHAEGGHEGGSVLTRDDESTIQERDDSVYSPIERSSGETGASSVLEVQEEYEQKESPTPSIYAASLFGGEEHNGKISPTSPHQNSLGNFGATFRRLQSRSRSRSGSSRADLSIPEDLDATIGQFPSDEDPGQTEADNSSQIGLQMAEGYENHVFAERIDNDTYSDGHRPTEPNSPPSICISPSEEKERSPRDSKRKSIPLPKLQSGFDYMSQSVITSTPLIVLEMPSSHTEISTDGSYGRSSMDDSRLRQSTPDRQLQVLHGGGASSPVYGNQSDSSKANPRRHSLSHGSVLSSSASTTSSKGYTIHRHIHVQTHGLGKVGKAPTSPLRREFSRDDDDVPEATMGYNEDMKRNTETYSAMSRTPLLPPYDPSEPYSHHRYGLRNIFTSIGHKGKNKQPSSPITASPTDLDPNGNSVDVDLVEVMEMDRTYTTPGANDDPFACAGGANGFADQRQSEQSSIHAIHLKAVGNSQEIADAVGKMEPGLGPLLESLAATPTQSIMGKAVALDVDYREVALHARPGHIGEFPTPIRMHSMLDKEEEESILALAEGGKDVVPGIEQVDQTNKVHSLQLPLHGNLVYSEMLSESPMSSRVSIPLLEAQMLGEETPEGKPFSMPEVNVHEPYEAPLEVLPKDLDIQGVLEPHDKNSTHNAPPEVPPKDLDTHGFLEPKDENGTHNAPPEPSHEQSNLDSSGEAMTRREYEAKALSPLELHPYIGEPSLKESSPMEPSIEKPQLEELQSGAPVAEDHASEEHVQDTRRSIESYVGVGQSPLLSAQTSTRSATLGSPKKSHNRNIFKRLIRRKSEDSMKDQQPLYKSPGMSRSQTLVSAASSGSNSPRSLSFFHRHHGNNNQQQQQQQQQQQQQQQQQGENQESDQNGYEYIERITQQIPEGYSSSDVNSGRPRSNSSGNLAKEGLTPVRSRPRSSTIHTTLRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQY4</accession>
    <name>A0A9P6MQY4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF962 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_001657</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001384">
        <property type="protein sequence ID" value="KAG0010237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQY4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046521">
        <property type="term" value="P:sphingoid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009305">
        <property type="entry name" value="Mpo1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28026:SF9">
        <property type="entry name" value="2-HYDROXY-PALMITIC ACID DIOXYGENASE MPO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28026">
        <property type="entry name" value="DUF962 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_8G05310)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06127">
        <property type="entry name" value="Mpo1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0010237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="100" mass="10788" checksum="3CC219D2426083A2" modified="2023-09-13" version="1" fragment="single">MSQSKVFDLKYQLLQYGSHHHNPWNVGIHLTCIPLILWTGLVFAAKTGPLIAAPSASAVASGAPLAVALSKVYRFCPPNLALLTMVGYTSYYIKLDKVAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MR63</accession>
    <name>A0A9P6MR63_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phospholipid/glycerol acyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001173</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001262">
        <property type="protein sequence ID" value="KAG0010802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MR63"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004366">
        <property type="term" value="F:glycerol-3-phosphate O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016287">
        <property type="term" value="F:glycerone-phosphate O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052744">
        <property type="entry name" value="GPAT/DAPAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31605">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31605:SF0">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69593">
        <property type="entry name" value="Glycerol-3-phosphate (1)-acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="447"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="495"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="458"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0010802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="820" mass="89766" checksum="4D89C205EAEE85A6" modified="2023-09-13" version="1" fragment="single">MSNLAIAIPVGLGITMDSVGPLSAVCTPLTTIHEEEEEHNITVTATTQDNYNSTCEGLSAKSAGLSINMPLLSPTMSSSSPLSASYSSCSSAVSSPLTLSPVLSPFQWTSDIRQYIMADIGPQPSNSEVPGMRNQMYLPRRRSSTKLGGLRSPGLGWSESDGELKGLGLTMPNYDAFHTAFIPQDEPLLVVSNHGNYLLDGLALLSTFPGQISFLMAQPNFQTAIGGIARKIGAIPVLRPQDATKYDSTSLVTITQDGTSITGDGIGIELDVGDTVYIECGSFEDITKDNRVTQCYGVVSRIVSDNEVDIKPPGLKWIPATLTSERDISYIKSRKIVRYGSLRIRVERGNTWVGINNALKEQEQEQQNGIATMASSATGTIGKFVQKIFSKSPEHESIHREFENGAFTGADIPGSLTAPPNFHTNESTPLLRKAMSIASSNHQVYSNAKRADSNARLSSFSTTRSSSVAGDADEEDDHGHAQAYDILLEQTLGRNSTTQETGSSSNNIRDATTYSALTSPTSTTIPMAAANKSRFPTIPCSFQYSRPIDHSVIYESVWKNFEDRRTVAVFPEGVSSDDYHLLDFKYGCTIMVLGYLAQHPSKTLRIIPCGLNFFNRHRFRSRFYADYGRPLTVPDHLVQLYCEGGESKKRACTELLQLIHSAVEGLTLNAPNYDELQLYKATRRLYGTGMKLSVPQKLELTRRFAKGYANLVMTPSMAALKRDITAFDKHLAHHRIRDWQLTADPSFLTALVLTLPSLFLLPALFLLSFPGTLLFGPVGLLATSAANYKGRQAMLAFQTYLPVSRWPGRDVIATWKIVVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MR97</accession>
    <name>A0A9P6MR97_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CDT1 Geminin-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_001104</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Cdt1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001247">
        <property type="protein sequence ID" value="KAG0010893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MR97"/>
    <dbReference type="OrthoDB" id="341730at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070182">
        <property type="term" value="F:DNA polymerase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000076">
        <property type="term" value="P:DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071163">
        <property type="term" value="P:DNA replication preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030174">
        <property type="term" value="P:regulation of DNA-templated DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1420">
        <property type="entry name" value="DNA replication factor Cdt1, C-terminal WH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045173">
        <property type="entry name" value="Cdt1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032054">
        <property type="entry name" value="Cdt1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038090">
        <property type="entry name" value="Cdt1_C_WH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014939">
        <property type="entry name" value="CDT1_Gemini-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28637">
        <property type="entry name" value="DNA REPLICATION FACTOR CDT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28637:SF1">
        <property type="entry name" value="DNA REPLICATION FACTOR CDT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08839">
        <property type="entry name" value="CDT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16679">
        <property type="entry name" value="CDT1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01075">
        <property type="entry name" value="CDT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CDT1 Geminin-binding" evidence="4">
        <location>
            <begin position="294"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="73"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="467"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="16"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="73"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="111"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="148"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="195"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="467"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0010893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="645" mass="72144" checksum="58D9998ABD7A9C4F" modified="2023-09-13" version="1">MTAGNQTRLGFVQKKPGSKRPLHSKHNKAGSDTSTVADANVTTLPTPAEESLERTGTLAQSMEEKLAAYKKAKEEKAALKTSRVSETRLLRTRTSTRESTKETITQRTTTRNSVNKSQTLLEFKQRTVNESQDSTTITSKPDDVPAESSDNGVSVQGNGEEVTPVAESPKSNIEGNTIPDVEAPTVEPKIDNDSVKSAATSSQITSERETEKLVSEDIILRRVSDHSDDDESDIHPLARTVVKAAPRKSLGRIISEESSESNHRREEVYKSSSTLSKISRKPIIQGPIVKPLPLPSHMSVLLANFKALENVLTFTKRQGQLCFYHKIKRHVELQSSRNFEIKHLAQFKTILPEGYQFMAAPCIFEGTKTRSILIEMLELKDDVEGNFIPQEEKRRSLFTKRLYDHIKQHHQNFLSSTTPSRTDTYPHSWHPDFDLESVAPIEESEVPLLKPAVVDISNVNLKDLGSRKDLAQRTSGEKSSEAPSSDTKEKQHETAEEPANETPESSGVKVLSKLEQLKERIRQKQLEKKEAGQKVATPEEKRQALIASRLPAVFDLIRFKRVDVMPLKTLAEQVVKSSRMPISEDEGRESLEMLAKVLPEWCDVFSLGAAGRYFKVLRDDDKGTKIVHDEKALRARLVANSMSNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRG9</accession>
    <name>A0A9P6MRG9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">YCK1_1</name>
        <name evidence="14" type="ORF">BGZ80_001460</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010001333">
        <property type="protein sequence ID" value="KAG0010469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRG9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14127">
        <property type="entry name" value="STKc_CK1_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000160">
        <property type="entry name" value="Casein kinase I 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050235">
        <property type="entry name" value="CK1_Ser-Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11909">
        <property type="entry name" value="CASEIN KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="19"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="324"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="355"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="410"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0010469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="440" mass="50174" checksum="F8B5B1BAF602DC5C" modified="2023-09-13" version="1">MSSSSHSTHSSSNVVGVHYRVGKKIGEGSFGIIYEGKCINLLNNQQVAIKFEPRKSDAPQLRDEYRTYKILAGSIGIPNAYYFGQEGLHNILCIDLLGPSLEDLFDMCGRKFTIKTVVMLAKQMLYRIQTIHEKNLIYRDIKPDNFLIGKPHTKNANLVHVVDFGMAKQYRDPKTKQHIPYRERKSLSGTARYMSINTHLGREQSRRDDLEAMGHVFMYFLRGGLPWQGLKAATNKQKYEKIGEKKQSTPIKELCEGFPEEFGIYLNYVRKLSFEETPDYDFLRDLFTKALKSMNEVEDGVYDWMLLNNGKGWESEMDGMRDIYGDGHVPSASQQYSANPLHPSGHHGTRDPHSQSQRQQGKVQQPALVHSNSKLKHKQSQSRGHGAGNTEQDLLRDHAYNRTAPNDGNMRPEDDQNAESQKKGFWDKLIGIITCGTCRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRZ4</accession>
    <name>A0A9P6MRZ4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001475</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001337">
        <property type="protein sequence ID" value="KAG0010440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRZ4"/>
    <dbReference type="OrthoDB" id="6375174at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14501">
        <property type="entry name" value="PFA-DSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004861">
        <property type="entry name" value="Siw14-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31126:SF18">
        <property type="entry name" value="PROTEIN-TYROSINE-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31126">
        <property type="entry name" value="TYROSINE-PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03162">
        <property type="entry name" value="Y_phosphatase2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="223"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="71"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0010440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="258" mass="29347" checksum="72F1F2CCBFC5BC2D" modified="2023-09-13" version="1">MLTPPEQFGIVEPGLYRSDTLHPSHFPFIRSLNLKTAILLTPELPSRAMSNFFEENQIRLIDLALGSWKNNTNNPSSNTNANNTNTSDGQTGQGLTTEAGGSNSVALATPSVPAALFQTSWWKPLSEELIKDGLEMILDANNYPIIVMDTSGIHEIGTFMGCLRRLQHWNFSSIIVEYRAYAGSKARYVNEQFIELFDIDWITLPDCLPTWWIEQEQMWREEQEEKDLQLEQEREAEAQRQNDLRQRQLTIAAEAAKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSE9</accession>
    <name>A0A9P6MSE9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ribosomal protein S5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RPS5</name>
        <name evidence="6" type="ORF">BGZ80_001145</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001257">
        <property type="protein sequence ID" value="KAG0010839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSE9"/>
    <dbReference type="OrthoDB" id="10264639at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14867">
        <property type="entry name" value="uS7_Eukaryote"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.455.10:FF:000002">
        <property type="entry name" value="40S ribosomal protein S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.455.10">
        <property type="entry name" value="Ribosomal protein S7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000235">
        <property type="entry name" value="Ribosomal_uS7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020606">
        <property type="entry name" value="Ribosomal_uS7_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023798">
        <property type="entry name" value="Ribosomal_uS7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036823">
        <property type="entry name" value="Ribosomal_uS7_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005716">
        <property type="entry name" value="Ribosomal_uS7_euk/arc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003106">
        <property type="entry name" value="PRK04027.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01028">
        <property type="entry name" value="uS7_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11205">
        <property type="entry name" value="RIBOSOMAL PROTEIN S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00177">
        <property type="entry name" value="Ribosomal_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002122">
        <property type="entry name" value="RPS7p_RPS7a_RPS5e_RPS7o"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47973">
        <property type="entry name" value="Ribosomal protein S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00052">
        <property type="entry name" value="RIBOSOMAL_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS7" evidence="5">
        <location>
            <begin position="40"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0010839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="201" mass="22296" checksum="13CCA7A5F86A995F" modified="2023-09-13" version="1">MATLALPAGIETDGAVRLFNKWSYEDVEVKDISLIDYIQVKAPVYLPHTAGRFASKRFRKAQCPIVERLTNSLMMHGRNNGKKLMAVRIVKHAFEIIHLLSDQNPIQVLVDAIINTGPREDSTRIGSAGTVRRQAVDVSPLRRVNQAVSLLTIGTRESAFRNVKSIAECLADELINAAKGSSNSYAIKKKDELERVAKSNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSR4</accession>
    <name>A0A9P6MSR4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ATP synthase complex assembly protein atp12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ATP12</name>
        <name evidence="6" type="ORF">BGZ80_000551</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATP12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001114">
        <property type="protein sequence ID" value="KAG0011623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSR4"/>
    <dbReference type="OrthoDB" id="5673at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033615">
        <property type="term" value="P:mitochondrial proton-transporting ATP synthase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3580.10">
        <property type="entry name" value="ATP12 ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2180.10">
        <property type="entry name" value="ATP12-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011419">
        <property type="entry name" value="ATP12_ATP_synth-F1-assembly"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042272">
        <property type="entry name" value="ATP12_ATP_synth-F1-assembly_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023335">
        <property type="entry name" value="ATP12_ortho_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21013:SF10">
        <property type="entry name" value="ATP SYNTHASE MITOCHONDRIAL F1 COMPLEX ASSEMBLY FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21013">
        <property type="entry name" value="ATP SYNTHASE MITOCHONDRIAL F1 COMPLEX ASSEMBLY FACTOR 2/ATP12 PROTEIN, MITOCHONDRIAL PRECURSOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07542">
        <property type="entry name" value="ATP12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160909">
        <property type="entry name" value="ATP12-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0011623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="271" mass="30522" checksum="DB6BA9F88AB0146F" modified="2023-09-13" version="1">MLRTLTARLASPSKAAIRSFHKTASLRDQMSRAEVSGKRFWENAGVKDMGDRVAVTLDGRILKTPAGNQLILPKDQKHIALMIAGEWHGQKTLLKSHSLPMTSLVARAIDGFIGNQQGRTETLNRLTKFLDTDSICYQQDFPDSIVKAQKEHWDPILKWVKDEYGLDIKVSQGIAYVQQDDEVKQKLWDIVNDMTDIELSAFERATLTAKSFLIGLAVVKRHLSVEDAWKAAQLEVLDQIDRWGEVEDSHDVDREFIKSQLASARLANLGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MST6</accession>
    <name>A0A9P6MST6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Methionine aminopeptidase</fullName>
            <ecNumber evidence="11">3.4.11.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">METAP1_1</name>
        <name evidence="13" type="ORF">BGZ80_000511</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 11">Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 11">
            <text>Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.</text>
            <dbReference type="EC" id="3.4.11.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <cofactor evidence="11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="11">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="11">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="11">Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="9">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <cofactor evidence="9">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="9">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="9">Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with zinc, cobalt, manganese or divalent iron ions. Has high activity with zinc; zinc cofactor is transferred into the active site region by the ZNG1 zinc chaperone.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Associates with the 60S ribosomal subunit of the 80S translational complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9 10">Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.18" evidence="11"/>
    <dbReference type="EMBL" id="JAAAID010001105">
        <property type="protein sequence ID" value="KAG0011678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MST6"/>
    <dbReference type="OrthoDB" id="3209743at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004239">
        <property type="term" value="F:initiator methionyl aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01086">
        <property type="entry name" value="MetAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.230.10:FF:000010">
        <property type="entry name" value="Methionine aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01974">
        <property type="entry name" value="MetAP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001714">
        <property type="entry name" value="Pept_M24_MAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002467">
        <property type="entry name" value="Pept_M24A_MAP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031615">
        <property type="entry name" value="Zfn-C6H2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00500">
        <property type="entry name" value="met_pdase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43330">
        <property type="entry name" value="METHIONINE AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43330:SF7">
        <property type="entry name" value="METHIONINE AMINOPEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15801">
        <property type="entry name" value="zf-C6H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00599">
        <property type="entry name" value="MAPEPTIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00680">
        <property type="entry name" value="MAP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52013">
        <property type="entry name" value="ZF_C6H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9 11" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 9 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9 11" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C6H2-type" evidence="12">
        <location>
            <begin position="6"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>a protein</name>
            <dbReference type="ChEBI" id="CHEBI:16541"/>
        </ligand>
        <ligandPart>
            <name>N-terminal L-methionine residue</name>
            <dbReference type="ChEBI" id="CHEBI:64731"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="222"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="222"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>4</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="285"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>4</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="292"/>
        </location>
        <ligand>
            <name>a protein</name>
            <dbReference type="ChEBI" id="CHEBI:16541"/>
        </ligand>
        <ligandPart>
            <name>N-terminal L-methionine residue</name>
            <dbReference type="ChEBI" id="CHEBI:64731"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="318"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>4</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="349"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="349"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>4</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS52013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0011678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="366" mass="40079" checksum="F27DBDCF89EF61E9" modified="2023-09-13" version="1">MSTSSEQLCQGLNCSKPAALQCPTCLKLGIPNSFFCSQSCFKENWGNHKAIHKIASLASGPPAEAGGSDPWPGYKYSGSLRPVYPLSPRRTVPDNIQKPDYADTGIPLSEQNIRSSSTIEALPKKDIDVLRKVCKIAREVIDIGVAAVKVGVTTDEIDRIIHEATIERGGYPSPLNYNGFKKSCCTSVNEVICHGVPDMRPLRDGDIVNLDVTVYKDGFHADLNETVPVGNVDADGLRLIKNARECLEKAIAMVKPGALYRDLGNVIEKHAKSEGFSVVKTYCGHGIHRLFHCAPNIPHYARNKAIGVMKVGHVFTIEPMINEGTWKDEMWPDSWTAVTQDGKRSAQFEQTMVVTETGVEVLTARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTF0</accession>
    <name>A0A9P6MTF0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NADH-ubiquinone oxidoreductase 21kDa subunit N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_011570</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000948">
        <property type="protein sequence ID" value="KAG0012692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTF0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053229">
        <property type="entry name" value="NADH-Q_oxidrdct_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019721">
        <property type="entry name" value="NADH-UbQ_OxRdtase_su21_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34062:SF1">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 21KDA SUBUNIT N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34062">
        <property type="entry name" value="OXIDOREDUCTASE 21 KDA SUBUNIT, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G04750)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10785">
        <property type="entry name" value="NADH-u_ox-rdase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="NADH-ubiquinone oxidoreductase 21kDa subunit N-terminal" evidence="2">
        <location>
            <begin position="10"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0012692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="86" mass="9347" checksum="BF61EAB72D4D772E" modified="2023-09-13" version="1" fragment="single">MSSAEQYIRTQYPVIDSDPHFTRVVSYMRHTDYIAWGGLTVAAPGILLAFERARPSGAPKGINFALGLAASIGFMGGFLFAYQKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTS3</accession>
    <name>A0A9P6MTS3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_011711</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000978">
        <property type="protein sequence ID" value="KAG0012468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTS3"/>
    <dbReference type="OrthoDB" id="9993796at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050562">
        <property type="entry name" value="FAD_mOase_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356:SF2">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356">
        <property type="entry name" value="FAD-DEPENDENT MONOOXYGENASE ASQG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040116495" description="FAD-binding domain-containing protein" evidence="6">
        <location>
            <begin position="21"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="7">
        <location>
            <begin position="6"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="7">
        <location>
            <begin position="291"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="429"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="440"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0012468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="465" mass="51792" checksum="6DD453F0249CA211" modified="2023-09-13" version="1">MSQRPKVMIVGARLGGLLLGLLLEKMDVEYDIYERYDSLKPYGAGMSLGANILPMFEQLGIYEDLLKISLPCSQMELYKEDMTPVSKVNISGENVGYDTQFFSRPDIHNLLLLKLPSERIHYGKKVLSIGQSEHGAIIRCADGTSYEGDILIGADGAYSAVRQGLYKRLEKDGKLPKGDSEPMEVGYTCLVGTTLPLGPEKYPVVKNNFSRFAIVIADKGLYSIVVISVPGNRVCWGVVIQLTPEEQEAALRNSEWAAKTIENGITPFAHHKTPFGCTLGNLVNETPKDYISNVYLEEKTFETWNNGRIALLGDACHKMLPSAGQGAINAMQDAVIIANCIYELGSSTSNEDIEAALQDYKEQRYAHAKGQVRNSSLSGQLFFSQTWFSRLVRWVALIFMPKEFDKASITKTAAYRPQATFLPLRERRGTMEIVPQKPSKRYEEEQRKKKTECDSPIPGTSPHAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MU08</accession>
    <name>A0A9P6MU08_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Exonuclease mut-7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">EXD3</name>
        <name evidence="3" type="ORF">BGZ80_011358</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000902">
        <property type="protein sequence ID" value="KAG0013023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MU08"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002562">
        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052408">
        <property type="entry name" value="Exonuclease_MUT-7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47765">
        <property type="entry name" value="3'-5' EXONUCLEASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47765:SF2">
        <property type="entry name" value="EXONUCLEASE MUT-7 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01612">
        <property type="entry name" value="DNA_pol_A_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3'-5' exonuclease" evidence="2">
        <location>
            <begin position="868"/>
            <end position="1060"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="12"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0013023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1065" mass="119817" checksum="2FF3025D754381ED" modified="2023-09-13" version="1">MPNPRYSGNTAPPTARQPHRQTTPRPPRSGSHSSDSTTKAFRSTKAATRSKPSKQRVVYMNYPSDCHVLEQKITQPVSATLQGAWNDSVLKDIQRMVATNNAFEVVHILLSSCQNIRTFQREIEIGNVDRVRQAIGDSMLRHIEDHGLFTIHAIISVGVISESRSLDRMLEKAISKLLSDPLRRILSSRRSDIQNQESRLLSSNSQQHSLQCPASKSAIAGIRGGENDLIIWDDDIMSEPDRTSPAQGRKSNNINLLDDDDNSISGTDCLPPLQPIVPPHRSLASKEPCREAISPQIPGSTMSRSGGNFRGNVYHTDRKDDDKLLDFWSGDRNALNSPDANRLSQVIALDPQHQRTSTITSEQPCGQQSANTNVSDAKEQNILISTYSSIQCDRPKGFGECPALIQPKHQQLLLNEIAAGKSILQVCAVLDIFNMRQCLSDTIPNIEHRVNDTFGSSLVRQLLDMEELDEAIAVVKGFIETRDRDIDLEILAQLMIAGDITRIHEFVGELHEVCTVALQYIDMRFSALIARWDQAGYFDHYSNPAYIDPLPTAVPSTEMLDQMLESKTGVRVALVEIAMSLIIRFDLEDSLLQSNTLFHGISFFAQYCTAITLLHGMSASGVLKTNSRHGKQAMENEGFTMLQSSWMILPYVIRLVRDDRRVQCMIIRHCILEQHDQVIAGFLAAKLDLGSVYQKWMHESDTVVNSAETTRGQRIVKPGVTEATEMIGVNNASSLDASPPNSRRHSNIIADPDDIKALFWSSNTEKSSPQISKPPSTPNLLSTHQTVNLSSTSTVPRGTSQKMFYSLPPETKVVIINHLDQFDQLRNSLSRSRVVGMDSEWLPTEGQNSWLQVHNLEMLRGSGEDGIKTKSSTPRTALLQLACDYMDCVYVIDTTKFDEDPSNRLGILLGDMFSNPAIQKIAYNWEHDKRLLERTFPILAQKRYRLQNFIDLRFIWLRFRDVQQTLPENMDRFDISKNNSNNENGYANPLEAWSKVPQGPPMRRFLFGGLSNMVQMLCGKPLDKTEQCSNWERRPLTKNQLHYAVVDARCLLDIHEILERAQRID</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUA4</accession>
    <name>A0A9P6MUA4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">E3 ubiquitin-protein ligase herc4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">HERC4</name>
        <name evidence="5" type="ORF">BGZ80_011369</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000905">
        <property type="protein sequence ID" value="KAG0013001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUA4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058923">
        <property type="entry name" value="RCC1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051709">
        <property type="entry name" value="Ub-ligase/GTPase-reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45622:SF70">
        <property type="entry name" value="SECRETION-REGULATING GUANINE NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45622">
        <property type="entry name" value="UBIQUITIN-PROTEIN LIGASE E3A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25390">
        <property type="entry name" value="WD40_RLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00633">
        <property type="entry name" value="RCCNDNSATION"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00626">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="3"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="RCC1-like" evidence="4">
        <location>
            <begin position="5"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="160"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="243"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="320"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="97"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="107"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0013001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="445" mass="48874" checksum="4E56247C46F8FD85" modified="2023-09-13" version="1">MPQSLFAFGSNGNGQLGIGSDEDTSIPLQVQFIPSLPSHIQQQHVHEDSIQTPFHDFAAGGNHTVFITRSEKRLYMTGSNKDGELLLQEPAQVFTRHEFSSDLQSKNNHDSSINKKEKEGEDLQRWRSVACGWAFTIAVTEPESTTKPDSTTRCRVKCINKAYAWGSGAFGELGLGPSVTKTGRKPIAIEKGLLGANTTTTIASSTSAIPSQIEILKVRAGLRHVLLLARENFLDGQEETSRILLMGWGSNRQGQLGVLERLDRSSEPFTEKELRDKFMEPTRIMIAKEQLTNNHNPQPAPVIIDMACGQNHSLVLFSDGTVYSSGLNKYGQLGPSATLDQETRDFRIGFKRIHGLPFVNSITCGWNHNAAMDSSSLQGKTTIYLWGRNDHGQLGSDIPLVLVDEIAMPGGGTSMETAAVATVAAMIDRMYLRRAKSASQIRFQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUD3</accession>
    <name>A0A9P6MUD3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphoinositide phospholipase C</fullName>
            <ecNumber evidence="7">3.1.4.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">PLC1</name>
        <name evidence="12" type="ORF">BGZ80_011260</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:33179"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:58456"/>
            <dbReference type="ChEBI" id="CHEBI:203600"/>
            <dbReference type="EC" id="3.1.4.11"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.11" evidence="7"/>
    <dbReference type="EMBL" id="JAAAID010000886">
        <property type="protein sequence ID" value="KAG0013145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUD3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004435">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate phospholipase C activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048015">
        <property type="term" value="P:phosphatidylinositol-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051209">
        <property type="term" value="P:release of sequestered calcium ion into cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00275">
        <property type="entry name" value="C2_PLC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16207">
        <property type="entry name" value="EFh_ScPlc1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13360">
        <property type="entry name" value="PH_PLC_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08558">
        <property type="entry name" value="PI-PLCc_eukaryota"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.190:FF:000039">
        <property type="entry name" value="Phosphoinositide phospholipase C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001192">
        <property type="entry name" value="PI-PLC_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037755">
        <property type="entry name" value="Plc1_PH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000909">
        <property type="entry name" value="PLipase_C_PInositol-sp_X_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001711">
        <property type="entry name" value="PLipase_C_Pinositol-sp_Y"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336:SF36">
        <property type="entry name" value="1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE BETA-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336">
        <property type="entry name" value="PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00388">
        <property type="entry name" value="PI-PLC-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00387">
        <property type="entry name" value="PI-PLC-Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00390">
        <property type="entry name" value="PHPHLIPASEC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00148">
        <property type="entry name" value="PLCXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00149">
        <property type="entry name" value="PLCYc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50007">
        <property type="entry name" value="PIPLC_X_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50008">
        <property type="entry name" value="PIPLC_Y_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="4 7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0807">Transducer</keyword>
    <feature type="domain" description="EF-hand" evidence="11">
        <location>
            <begin position="466"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="domain" description="PI-PLC Y-box" evidence="10">
        <location>
            <begin position="772"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="9">
        <location>
            <begin position="895"/>
            <end position="1017"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="134"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="728"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1092"/>
            <end position="1266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="11"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="195"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="220"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="245"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="742"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1092"/>
            <end position="1108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1109"/>
            <end position="1151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1158"/>
            <end position="1168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1170"/>
            <end position="1182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1183"/>
            <end position="1210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1236"/>
            <end position="1245"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00059664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0013145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1266" mass="140804" checksum="D23BA4A77375A593" modified="2023-09-13" version="1" fragment="single">MFDKIKKAISGWSQDSMPQSSSGPRPVDPSLSKTKRNHSFRNSLPARLKPPFYRQESSSSSEVLPLPPPKDNVYNTAALSQPRTTFIRRTSSFHSQKESSESGKVEVPDEDIIMFTSTPPVSIIPSSSARIPRGAANLPAGSPDQAVLSSSQESPVVQWPRGGTSAANRSQEHFLRTHHRTSTSSEASLKEMQANMATTPPATSVLRQDSQRPSLDRQISRSNVVGGSSATTEPQQTQNAGHTKASSSDCSAESTESHAVAASGAVAAAGSIATPPSDNTQQLIAQESDATKASSTETLPPLSPTVVRQLSAGILMLKISAKKQHSRNFKLDLEQGRILWDSRKFGRINVEQIKELRKGKAARMYREQLGVKPEHEERWLTIIYSAMGKYKTLHLVAPTKDKYEDWIMAVERMWSVKREEADGLPQLQRKTSQWLKEHWMDADKNVDSKLGYEEIVRLCYRLNINFSRKEIRARFDQADEKKQGSLDFSDFTRFVKLLKERKDIIGLFYKISKSDSMTLGEFTDFMVTTQKSKLDEDQIKEIYGKHVDKTIEKFSVDSLASFLLSVDNSIVSPKHMYVHQDMTQTLSSYYISSSHNTYLLGHQLTGISSIEGYIRALQSGCRCVELDCWDGPDGQPIVYHGHTLTSKILFRDVIEAISTYAFVNSPYPLILSLELHCDIAQQEIMANIMRTKLGSWLVVAPIDSNTTSLPSPDQLKYKILVKSKVLPPGNSSQELSTDTESESEKESESDSEGAKVQKPKTKTKKVRVARALSDITIYCQSRHFSGFSHEDCSPYKIVSLSERVSLRLAKQSLQEYINMNKTHLTRTYPAGFRINSTNYDPHNHWAAGAQIVALNYQSYDRGMQMNTAMYAMNGRCGYVLKPQSLRLAPGEFCNHDKAPSFSKTHPVEITLQIISAQQLPRPYEAVSGDIVDPVCEIELHVPGLPYIKQKTRHISDNGFNPMWNEEFKFRVDYEHHELVFFRFVVQDEDIKFSDLVASYCISLDCMEEGYRHIQLVDPSGDPYLYSTLFVRINIEPVPQLYTLDAALSSAPHRDGFSLTRPIEEYSHMAVDSYHSAQNAIMSAVEVLHSSQGMTKSSEVQQTPQGTIKSSVEVQQSSQSSIKNSVEVQPSSQTTTTSSTEVQQSSQTTTKSIVEGQHSSETTTTSAAEVRQSSQTTTKSSAETQHSSQTTTRSVVQVQHSSQTSTSSTTTKRVAEVRHSSNVITKGGLEADCNRSLPDLPGTPLALTPPPPSQTPDIVALPPSPPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MV69</accession>
    <name>A0A9P6MV69_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">L-asparaginase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_010755</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000785">
        <property type="protein sequence ID" value="KAG0013933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MV69"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004067">
        <property type="term" value="F:asparaginase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006528">
        <property type="term" value="P:asparagine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1170">
        <property type="entry name" value="L-asparaginase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036152">
        <property type="entry name" value="Asp/glu_Ase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006034">
        <property type="entry name" value="Asparaginase/glutaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020827">
        <property type="entry name" value="Asparaginase/glutaminase_AS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027475">
        <property type="entry name" value="Asparaginase/glutaminase_AS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027474">
        <property type="entry name" value="L-asparaginase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037152">
        <property type="entry name" value="L-asparaginase_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11707:SF28">
        <property type="entry name" value="60 KDA LYSOPHOSPHOLIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11707">
        <property type="entry name" value="L-ASPARAGINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00710">
        <property type="entry name" value="Asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00139">
        <property type="entry name" value="ASNGLNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53774">
        <property type="entry name" value="Glutaminase/Asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00144">
        <property type="entry name" value="ASN_GLN_ASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00917">
        <property type="entry name" value="ASN_GLN_ASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51732">
        <property type="entry name" value="ASN_GLN_ASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="L-asparaginase N-terminal" evidence="3">
        <location>
            <begin position="36"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="45"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="218"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0013933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="236" mass="26067" checksum="2AB56419F1C74917" modified="2023-09-13" version="1" fragment="single">MQRPSIQLDTIAFENAAVDYQLSQFIDEMLPCEVSRVLVIYTGGTIGMKNTKQHGYIPVPNYLADTLSSQARFHDLLSLNTVFGRLSRTSSGVNLNTLPVTSLNKHLDPAMNGLHSHHTIPPEQATINGTASGATLPPNTPVNKIRLPCFAHLPNKQGKIPSLITPPSLYGKRIRYSILEYDPLLDSCNMTMTDWVRIATDIEANYELYDAFIVLHGTDTMAYTASALSFMLEDLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MV87</accession>
    <name>A0A9P6MV87_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ricin B lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_011019</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000835">
        <property type="protein sequence ID" value="KAG0013524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MV87"/>
    <dbReference type="OrthoDB" id="1887033at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901136">
        <property type="term" value="P:carbohydrate derivative catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041036">
        <property type="entry name" value="GH5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052066">
        <property type="entry name" value="Glycosphingolipid_Hydrolases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31308">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31308:SF3">
        <property type="entry name" value="ENDOGLYCOCERAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18564">
        <property type="entry name" value="Glyco_hydro_5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00652">
        <property type="entry name" value="Ricin_B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00458">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040446556" description="Ricin B lectin domain-containing protein" evidence="5">
        <location>
            <begin position="23"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B lectin" evidence="6">
        <location>
            <begin position="488"/>
            <end position="624"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0013524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="631" mass="69164" checksum="6D43FD70FF6DBED3" modified="2023-09-13" version="1">MKTLSITTAIGVVLSALQVVQADLSKIVRVNPSTQMFIDAEGRSRFFHGTNMVSKSPPWHLNVDTFVPGRSIVEKDIEFLKSINVNSIRLGVHWAGVEPVRGQYNQTFLDISNGIIQKLQDNGIYTLVDQHQDVFAEQLCGHGVPLWFVKPGWVTASHGFPVPQTSSPFSVDANGIPAESDCNSIDWSTSYLSYAVGNAFGRLYNNYDNLGDSWAAYWNKVASSYGSLPGVMGYDLMNEPWVGDHMADPTLLIPGKADGVNMEPLWNKGNTAIRAVDNTTIVFFEGSTFDILNGFNNVPGGDGSKTAQSYHYYKPPQLSTIDVTIKNRITDATRLKTTGMLTEFQFWDSSPASLALIQQAVYEADNYLQSWQGWAYENLWRSDGTFDPLLARTYARTYAEATAGATKTLYFQDVTGKYWVSWAADTSITAPGLIRIAPQYYYPDGIRVFFTPANAGTYTMDGTNTVQLHYTSQAQNGQTIQASVQPFFPTDVVKNGASGKCMDNSKSAVTPNNLILLWTCNSTANQIWKFKNGTISLAFDPNNNSDTFCLDTQTISGKTYQSAVLNPCNGSATQQWTVNSSGNIINGATGNCLDITGANYSEGTPLISYPCGNPTQGNQVWTLPRGANGVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVD1</accession>
    <name>A0A9P6MVD1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_010919</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000815">
        <property type="protein sequence ID" value="KAG0013674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00821">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45615:SF80">
        <property type="entry name" value="GRIP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45615">
        <property type="entry name" value="MYOSIN HEAVY CHAIN, NON-MUSCLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="3">
        <location>
            <begin position="403"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="103"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="167"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="226"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="305"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="696"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="833"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1366"/>
            <end position="1500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1777"/>
            <end position="1801"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1830"/>
            <end position="1852"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1932"/>
            <end position="1986"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2005"/>
            <end position="2064"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2065"/>
            <end position="2127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="40"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="103"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="167"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="235"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="260"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="305"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="373"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="696"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="833"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="857"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="881"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1370"/>
            <end position="1385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1394"/>
            <end position="1407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1417"/>
            <end position="1432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1440"/>
            <end position="1460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1470"/>
            <end position="1495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1777"/>
            <end position="1796"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1840"/>
            <end position="1851"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1934"/>
            <end position="1962"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1970"/>
            <end position="1980"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="2015"/>
            <end position="2024"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="2034"/>
            <end position="2044"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0013674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="2178" mass="238485" checksum="5AD2A4664E3BE11A" modified="2023-09-13" version="1">MNTTKQYDQQQQQGYRPPPNMVATGRPLPKTPGVQQQLDPSMPTSTSLGSSSIGNSIFQNIGNAINDSNNKNDGVSARRVSIHFNQPSFALAPASSNNFNTTTTTTITGTGTTTNNNSNTTNSRNAHWIQPKVTPSTSFSNIQTTYPAGVNSNTGSSYSNTPLCRKSQQYLSQSQQHQQQQQHEQQQQQQHEEQQQQQQQPLPRLSQDEESSYYAALTRPISPTMVMGYIPPPTSSGANSSVQNGSTLGSPGHPIPPPVTSTISPATASSFGPHSATAALSSSFNTLGPGSQPKPAIHQSARNSYVHPTTTVPGPGSNRTQQGTNSIDPEDSTSSSSRFARRGPLMMSHDVGSFGDGTRSRRESAAYSDNMDSPASYQQQFQTQQQAFSPSSQRTDGSGAHLQVAKEGWLWRRGNLLTWKRCYAIGRYRGDANPGIMTLFKDNEHLFPIKSIDMAECLEVQVKGQDAKATGRFEFKVVTRKEEIWFATDTMSERTGWIDALNSLMAKVVGASLMKLEAKLNNIRQRNNSFEYTQTSAGAPSNEKATVLEGQLQLVQQDLVSREQLLSQREQELDRKRAESLLVQLEAWRAAAKVTVNQHYAVRDQLLERVMKTARTVQELIERARIHLETGSDQITEIVNSHLECLKVHAGESSMNSTSYKMLKSILVGLSVNLDTRSSEIKRVLLTLDQYISATKSSTSTSTPASPTSALSPASTKDRRMSVGASFHSSGPPPPASSASVGITVYLIQVRGKYKETLEILEDHSRRLKRILEHADINDPETARRFHEEAKDLLKGLLKLPSYVFTPCLPDQPLPGAADTFYREDLVQIQQKSKELQRKSHTFEEPSSFRQASGHHIKQDGSEPAAKESATEGSTPKIKQVPTTPATASANSVAPPKSALALPAYLSSFLSTDNNNDNITHGFSTADLTQKLRDTILPEFDHLSVKQEESLQSMTSLLNQISSVLVSKLAEVKDATAGQRQEFEELKDEIIDMMQLSATDPSAHQRDVSALSEIRSKLAEITEQLIKVQSSNSQAQQGFLGSGNNASYNSNRRLIGQSGSDNATGSSAAIKTGFSLLQRSASTMAPSSFRGAHPFYHTIDSGPRQHLQRVNSTSLQNRLQIPSSVSLTAGFAGTGLASLETPGAASTATVGGKHPKIAGMARLFEDGDGLGTNDNDHQHPSRVSYFQDYDYDQDSRQHSVNNQEVVSKLDQLLLLLEFVNTAQCRMMAYQDLEFDRNKSQGSSNVDDGRMMAVQDHMEQMDRKMNMQIHLLRRLAALHDSGGANAEEPLAIPSAQIQEIKDEGVSGEFNDEIDNAHLESVADMRGVKPATVNQPGDDLSFLDVLSRLDLQVIPFVKDQSSRIQELSDQLSEMKRQLDEQQRRQEQPRSPLPPRVSTSIGLGRSNSLENPAVPILRSRSPSQTFVQQQQSINPLSPALEDSPSSWRASLRPSHSTGSSSASFKDRAFSAVNASPLNNSTSTNSMPSSSASGIGSQSNQDGLILSKTSDRIAEILDRMDTRMGQMIDEQLSRYEKGNKVLLAKVHELLETDGDEAEGRVVANRREKPQEDDGLIAMNASSSAVISESDLAPLQQKLEGIEQILTLQTDRNELQQVENKALWKEIGTSLDELHGYQAISKESQQQLTKDVRETLEQVLRGQEELLSKSAQNRGVGSIHETIQESVESAAKLDLAESFEKIKSLIQQEADRSEFSLNEQRDEILEKMNQIMSSIQESQADVGSRDAAVKEELQEMREWIVKHSSMQTENLREIVFASISTHTGPETSGTTENGIASGSVDSESDTVVIGGNGSGFGSEEEYTKVDILDDLGRDSLIHDNPHATPLSSRNQSQPLSGATKEIQELKEQLEMFTKLQMATFSELADNVSGIEKMMLDMSKTMGVRRGGTILRKKEADQDRAMLAAEVKETIEEVMTRMKSSSSVPLLSGVSSNSLSGSQKGSASRSSLDSGDDKASPVSPTSSAPANGLSRGEGGLLKYLYQPRRLASVAAAGAGAPQPPSRVTASSPLPTVTGKPLMNVDTSFSLTDATRSPPPLTPSPSMDYSEDEGQSRDMEAQLNLYHDQMEQLYRRKARVEIEVENLQSEKSQLSKENEDLRNQVEQLKREKQDLLLSRRSGSSEETIVEQSSSTSAILEKALSDRVAMLLQETARLEALKKQLESETA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVV4</accession>
    <name>A0A9P6MVV4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 16">Phosphatidate cytidylyltransferase</fullName>
            <ecNumber evidence="6 16">2.7.7.41</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">BGZ80_010443</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 16">
            <text>a 1,2-diacyl-sn-glycero-3-phosphate + CTP + H(+) = a CDP-1,2-diacyl-sn-glycerol + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:16229"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
            <dbReference type="ChEBI" id="CHEBI:58608"/>
            <dbReference type="EC" id="2.7.7.41"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 16">Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 16">Belongs to the CDS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.41" evidence="6 16"/>
    <dbReference type="EMBL" id="JAAAID010000727">
        <property type="protein sequence ID" value="KAG0014434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVV4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004605">
        <property type="term" value="F:phosphatidate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000374">
        <property type="entry name" value="PC_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016720">
        <property type="entry name" value="PC_Trfase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005226">
        <property type="entry name" value="UPF0014_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13773">
        <property type="entry name" value="PHOSPHATIDATE CYTIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13773:SF8">
        <property type="entry name" value="PHOSPHATIDATE CYTIDYLYLTRANSFERASE, PHOTORECEPTOR-SPECIFIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01148">
        <property type="entry name" value="CTP_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03649">
        <property type="entry name" value="UPF0014"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01315">
        <property type="entry name" value="CDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="13 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 16" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="15" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 16" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 16 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 18" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="15"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="145"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="176"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="525"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="619"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="648"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="672"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="710"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="793"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="206"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="249"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="294"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="351"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="212"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="299"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="312"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="353"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="373"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="386"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="402"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="427"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="446"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="466"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU003938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAG0014434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="913" mass="101916" checksum="28025BBEAD3F472D" modified="2023-09-13" version="1">MGLVLQHIFDADSPILVILMALLLTLLGANEAVFNVSKRRHIYMFPSVLVSMGCSCLIIGTFGTRLAMGVDPLRSPKEFIPALGMLLGNTMTGITLGLDQCLSQLSDNKEKIELYLSMGATRWEACRPVAVEAMRRAMMPTINQMSIIGLISIPGMMTGQLIAGASVMNAAKSQQIIMFLISGAAAFGTLSSVLIYFTPVISIMTKSKSPRRNSSNNRSPPSPKSNGNPNASPNASIGAAAAALHLATIGNTTPPTSPPPSPKRVKDNHPSTSNEVKSKVLSTLGEVKEISMEAHAETGVSNRKQSSVKSASLTTISTTISSSTSTTRGGRSNTLSPSVLSYTSNNLFSNLRLDQRTNENSNDNRNDIKGAESDTESESNYDSELDYSSSSSESSNSIHSTDDEDSEEEVDDDEDSEEEEEEKTKPHVQQNLATNDNIATRKTKQQKQQQKKQQQIQKEEIKNPIQQRHTPPQEEQQQREQQHQRTRSKSQSPVRQGKEPEKETVVLLADESAKTKWANWSVRTLWTLIMIGGFFACIAAGPLFVILLVVMVQSLVFKEVIYLAHVPSKEKKLPWFRVTNWYFLFSTNYFFYGESLIHYFQHVVFVDAFLLPFATHHRFISFTLYVIGFVFFVANLKKGHYRFQFSQFAWTHMTLLLVVCQSHFIINNIFEGLIWFFLPASLVISNDIFAYIFGFFFGKTPLIKLSPKKTVEGFVGGWVMTIVFGMLFATLFLRYPYMICPVKDLRATAFSGLTCELNPVFVPVKYYLKPWMVALVRHLGIRSNHVMIAPLQLHTAVMACFASLIAPFGGFFASGFKRAFKIKDFGHSIPGHGGMTDRMDCQFMMGLFSYMYYQSFIKTTALSVGVVLQSAINNLQGQEQMELFNHMRQYLIGQGLLDEESCLVVPPKEAWIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MW14</accession>
    <name>A0A9P6MW14_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_009633</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000594">
        <property type="protein sequence ID" value="KAG0015799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MW14"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050508">
        <property type="entry name" value="Methyltransf_Superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42912">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42912:SF80">
        <property type="entry name" value="METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase" evidence="2">
        <location>
            <begin position="136"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0015799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="275" mass="30694" checksum="2905A6E741F4094E" modified="2023-09-13" version="1">MGVIPPSPQVLDIKDAAMSANHDQHLPSPSDSESEEPEGMGDRKGSKIEEPCSIGHADADPICYGRVKDPEAMVSKTWWKSVFGDGLYLQTDGDVVEDPAITLDEVRMLESRPAVRAILERSNKMPLSDQDKPVRVLELCCGQGRHAIQLAELYPNLHIYGHDQSQYLIGLARSRAQAANLIPRNEDSPQASPPSPTYDDRVQFTVGDCRFIPHADNQFDFILMMGNSFGYFSNDQEDVELLKEIYRVLRPGGVVVLDLVDGAHMRENYSPRSWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWT5</accession>
    <name>A0A9P6MWT5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_009083</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000518">
        <property type="protein sequence ID" value="KAG0016607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWT5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="238"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="297"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="466"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="318"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="496"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0016607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="623" mass="65969" checksum="67A5211C0A6815DB" modified="2023-09-13" version="1" fragment="single">VAQQAAENQLGEERLQRLALAEEQFRERVQNGIRKLERKKRGEPTNAPPLGISTGKVERSLTESKLGIDRQIVNIIAESSTIYGPDKNLDKEPDLDPDQDLMILFGLDPEYTSMKHGKVEAEDEKTLQDQQPTGISFAESTVRGGRRARIRSRIKARMQGNLALSPSSSDLKPAEHISRPPQSQLSSLQRLEAMVIRYIKWLHILIQCRQLLCRKAVTPAMALLGSHLQPTVATTSYFDNPTSLSSTVGSPTISITESSDPRPPPLERRPSDLMSVGSSSTVVPAHKGLQKAIATTATTTAESVTPESGLTGARGSEDSSLTSSPTTAADSASNTTTPSISSSLSSLSSSVLGAGPVSVTLSQPASGTASGRIIGSRTLLSATAALEAAANSANHAHTSGAGQGSGSSGMHHPFINDMLTNHLDPLSASVSEAIRKSSAKIKKSVVDPLATNTNNLFKYSPMMVVGGHHQQQQQQEHQESRATTSTSAPVKGFYRPPTATSSDASSVVSLMRPGSSGIRRSLSSSSSSTFHSASVAVPSSTDGGYVGVKPAAGSSVGRDSEDHSTLNDSSYPASRLNAIEADDDENFLSILDVGHPGHQMDDEVFRILETLGLATSSVYTTQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MX05</accession>
    <name>A0A9P6MX05_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_009475</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000571">
        <property type="protein sequence ID" value="KAG0016042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MX05"/>
    <dbReference type="OrthoDB" id="2442223at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="265"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="344"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="407"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="153"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="275"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="344"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="449"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="469"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="494"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="509"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="521"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="546"/>
            <end position="555"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0016042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="555" mass="60194" checksum="30599EEE19E5DE9F" modified="2023-09-13" version="1">MIPAEAIVGIVLGSVFIVVACGAVLYYFWDHIISEFSQTQQQAQEQMRQVVDQTVPPDYNRHELDPVCVFEHELHPYVVAGAQPILVHSSSADFIIPPEEDPLVIASTPRASFMPFPEPTSTFSADVQENTNNIPASIATPAAAAAAATATATATGDSNASEIQESQSPESQISITPNPSTPTSGLSTGPPRFVNQSMLNMAHLASPPSYDVPNRVVAVSPLSIPHSRHHHSRSASDVPQFMPSPANTLGMQQSYYGQVRTRSHTISHPEPYQPPTTTVTSATQEETPDTPRYSLEFPSNVPHERHLEEHQRARAQYEQWELFHRQEHSILMQGQPFSQFYSPSVSTTSSFTPNTRDAVFGSGSPSSSSSILGRGRANSGGRPRASTIGESSKLLIQRMQALLRRTSQSAGGAGENGGFSPRFENSLTPNLQQQQRQRQEMESGFVGLGIEQQQAQQQGEHQVQQAGEAETEAETEAENSNDVAIVVEPEEESNGSSSPSSTSPSSSEQRQEEQDHHEDSSVASVHSTQISITRTRHSEAMDLSIPTISAPLTAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MX96</accession>
    <name>A0A9P6MX96_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">FKBP12-associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">FAP1_2</name>
        <name evidence="12" type="ORF">BGZ80_009653</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NFX1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000598">
        <property type="protein sequence ID" value="KAG0015747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MX96"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06008">
        <property type="entry name" value="NF-X1-zinc-finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd02325">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.50">
        <property type="entry name" value="R3H-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034078">
        <property type="entry name" value="NFX1_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001374">
        <property type="entry name" value="R3H_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036867">
        <property type="entry name" value="R3H_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000967">
        <property type="entry name" value="Znf_NFX1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12360">
        <property type="entry name" value="NUCLEAR TRANSCRIPTION FACTOR, X-BOX BINDING 1 NFX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12360:SF12">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR NF-X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01424">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01422">
        <property type="entry name" value="zf-NF-X1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00393">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00438">
        <property type="entry name" value="ZnF_NFX"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82708">
        <property type="entry name" value="R3H domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51061">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="R3H" evidence="11">
        <location>
            <begin position="524"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="793"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="27"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="59"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="73"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="86"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="101"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="138"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="794"/>
            <end position="807"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0015747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="852" mass="93421" checksum="8264355A2160D746" modified="2023-09-13" version="1">MPTTTGQPVAQVDLLPKDLNPEAINATKLSSQSSTTNKMNLRGNSNNSKNSNADSTRLRNSHPGRRRPAGRIDNADNNKEIATDHSQSSRGSASGSGSSSRSDDIRQKGKTVDRSGISARVAAHRQEENASAPGLHIPSSSDNKINANGTSRRQRRASHTAKFVHKVEEDRDLMEALTVGLTKSTYDCMVCWDVIRPAHKIWSCQVCWAAFHLDCLSTWAKKSSEGKNYRFCPCHPGPCPPCGGLGPIQSCYCGSESFQLRCVDTDFTFQSGKSCNQVCGELLGCGKHSCSSVCHPGLCSPCEEEQVQKCYCGKHERMARCGDGIPKATLIDGEEQTGYYECKYICKSEPCPPCTLLVTKQCMCRKSKMPSVPCYTTQTSCGKTCGKGLDCGSHKCNRSCHSGECTISPSEACSQSCLKSRKSCGHRCKVACHGQDPCPEGQPCQTLVVTSCKCGNLTKEIVCGASAENPWDGKPRIIKCNDFCLIAERNKRVALALDIDDSTIGGPRIPHFDDYVLDYASANMEFTLKIEKRLAEWVSDSTLQTLNLQPMKGHHRKFVHELASHYNVTSESVDVEPYRSVVIHKKLNTSVPDVLASQACRQRRSNTSTISTSGSGGGIEQLRKSNIKDPINAIYLHDLANGLTRAELSAQLAPIFGNIKYGIRWLTDDDAVLVPHPGNMSMDEFEILLVRLRTGIKSLVTNGQLCERVELCWMNKEGEVIGHTSVGQPKRFFNAAQGNQLLKKPAPPKVENTFSILDDDERVAAAKKAEEEVIMKAKEAAGTLSLEAWEEDANNSFSSSTQKTTRPPSAIDAYRSDGSFSSLKSKITRKADRNVVDDWQELLDDDVDDDQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXJ0</accession>
    <name>A0A9P6MXJ0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Vacuolar protein sorting-associated protein 54</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_009324</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
            <location evidence="1">trans-Golgi network</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VPS54 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000547">
        <property type="protein sequence ID" value="KAG0016277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXJ0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000938">
        <property type="term" value="C:GARP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019905">
        <property type="term" value="F:syntaxin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006896">
        <property type="term" value="P:Golgi to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.860">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039745">
        <property type="entry name" value="Vps54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012501">
        <property type="entry name" value="Vps54_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019515">
        <property type="entry name" value="VPS54_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12965">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING 54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12965:SF0">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07928">
        <property type="entry name" value="Vps54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10475">
        <property type="entry name" value="Vps54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Vacuolar protein sorting-associated protein 54 N-terminal" evidence="10">
        <location>
            <begin position="180"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="Vacuolar protein sorting-associated protein 54 C-terminal" evidence="9">
        <location>
            <begin position="896"/>
            <end position="1027"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="45"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="506"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="603"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="862"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1153"/>
            <end position="1184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="20"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="47"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="514"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="608"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="634"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="862"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1164"/>
            <end position="1184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF10475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0016277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1184" mass="130566" checksum="9F2D6BAB3920809D" modified="2023-09-13" version="1">MAAGPSRPFRPSHIPRRDSTSSTYSTLSEASQPWTRADIGFNAISGVLNNPTKRPSSTAKPTKTDIPPVTPAPVRKVKVSEFDSYIKHITPVFERYQSNRAGAKPSDETNVHSPRTPFGSSLESLATHLQPQIMSPSSNQLAMDTIDRTESARNPYSVPDMPELDEPVPMKPTLPDTPALNSVPSIFFDPDFNFENPRTFDLVCEQTGPSLEGKNNTTSIVTNSILQEKLSHYLDTVEIHLMTEISRRSTSFFEALSNLQALHSQTLECVSQIHVLRAQLARIDHTQSKQGLEVVRLKRRRRNLGLLHNGIRIVKEIRSTQPMIQVLLGKSDYFGALDLIDGAQSVLIDGDMKHLESTPGFDPSLTLVPSSSAITPSPRSLDIRGVLALVHFGGQLTEMRRMIGKMMESDFVNLLLDDFRVRIGKLDVATLLTDLSKVDTINTKFTKPNFNRGINPLLSTQVEQESDLQDKMLPLIQGLFRANRAEIALQSYREQILQEIKNIIKSQYPPPDPNSLNSSGSTSAKKKDQMAALTKQLREMDSLTFYKMLSYIYAFLLGAFQRVSLYHQLTLLCIRKAEAQGIGELIMADSASDTDSIQESISIREMKDEENENDENEESDDNEDQSDGEGTGFSLGTNTPGSTPLQTTMGRKRLVQSSKTMSPGTPLTGGARSPPIHGFRALQLNEEEEDGHLSASTVAQLFRQLETESEAILFAVADLAHSRCAKLMGMRSEQTAKLLPAEVYRLLKLTWSFVLQSELLSGYMCYGLRTAILSQSKAFLLQFHMEKTSQLALSVGEDQWAQVEVPWSSQATANELVAISMLSLQEARNKDFTMTFNILTLSAPPAIQGLDDHESYIPSLLGSKGSKGSNGSMGSSKGGAKAEVPAPTRVLSIRDEVFFVVGCSLVLLDILAEYLDILNNISLLTTDVMQRVIELLKLFNSRTCQVILGAGAMRSAGLKNITAKHLALASQSLSVFATLIPYIKDWIRSKMTDKQVVMLTEFDRILRDFQEHQNEIHAKLVTIMTERLALHMRSMTNPAVVDYDALNKPAQQLANGGGNVNAFMDGLVKDVITLHKVLSRFLPAASMRRVIDEVLQIFTTRLEEEIQKLPIATPLGKTRLQADVAYFGQKLGPVDPNGIIGSRLMKQVKELTLEDKKNATSPPTGGAAQTNASAATTAATSTDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXV1</accession>
    <name>A0A9P6MXV1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_009072</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RRP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000517">
        <property type="protein sequence ID" value="KAG0016615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXV1"/>
    <dbReference type="OrthoDB" id="2019504at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030688">
        <property type="term" value="C:preribosome, small subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010301">
        <property type="entry name" value="RRP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13026">
        <property type="entry name" value="NNP-1 PROTEIN NOVEL NUCLEAR PROTEIN 1 NOP52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13026:SF0">
        <property type="entry name" value="RIBOSOMAL RNA PROCESSING 1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05997">
        <property type="entry name" value="Nop52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="223"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="333"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="226"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="244"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="278"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="334"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0016615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="355" mass="40880" checksum="C0BC3ED6B112024E" modified="2023-09-13" version="1">MVVVASAKDSSSPFGKKLAANDKKTRDKAVKALGKWVSKKKDFTHLELMKMWKGLFYCVWMSDKPIVQQQLSETLSSLIIRVPREGVMDFIATFWETMCAEWHGIDRLRLDKFYFLLRRFLSYSFRMLKENEWELETIEEFSNVMINGPLNATSTKVPDGIRFHLIEIYLEELEKIVDVAHSGEVPTAHILQPMFHILGHTINGKVFKMVAEEVFESILKKTAAGEGDDSDFEEDANLTVFDKTEDDDEDEDDENISDEEMAEDDSDDDEEAKAQAEMEMEMDDEIADQDSTTFDYDLIGIKERLSKVSADEETVEQNRRKVLVLYKAYQDFCPLEEDDSEEGEGEGEESEEDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXZ1</accession>
    <name>A0A9P6MXZ1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008832</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000493">
        <property type="protein sequence ID" value="KAG0016879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXZ1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="233"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="308"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="116"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="208"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="321"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="334"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0016879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="359" mass="39693" checksum="0CA4B1B3C28FF347" modified="2023-09-13" version="1" fragment="single">MESQLSGSLPRQHQQHFLVQQYQLFTQNQFPLQQQGILPHQQQQQQQQQQVLDAQLQWGNSPSPNTLTGSISARNNQLPSRQSSSKFPPGSFPLLPSKGSAPGQQPLNHQQERPRSISIQSGSIIPSSTSNNSVSYNNHRFSRTPSPNRSNAHSPPPPLTLNNTSGSGYSTGRLSPVSVFSNTQPMYGQGQGLQDHVVSPMSSNPSVQQQQQQQQQQQQSINVASLATARIANHSTSDNTTRFDGLARSNSNSQWYQTSPHPDQTPLSIPQTLFLGQPELLQSPYGSSGPLEPVFRPPPTLMPYPAYQQQQPQLQRMGRPLSTQMGYSGTPMATPQTTQQRMVQQSQPHTPVFDAQKQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MY79</accession>
    <name>A0A9P6MY79_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AP180 N-terminal homology (ANTH) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_007624</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000394">
        <property type="protein sequence ID" value="KAG0018033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MY79"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005905">
        <property type="term" value="C:clathrin-coated pit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030136">
        <property type="term" value="C:clathrin-coated vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005545">
        <property type="term" value="F:1-phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032050">
        <property type="term" value="F:clathrin heavy chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005546">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048268">
        <property type="term" value="P:clathrin coat assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072583">
        <property type="term" value="P:clathrin-dependent endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006900">
        <property type="term" value="P:vesicle budding from membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.150">
        <property type="entry name" value="ANTH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011417">
        <property type="entry name" value="ANTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014712">
        <property type="entry name" value="ANTH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045192">
        <property type="entry name" value="AP180-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22951">
        <property type="entry name" value="CLATHRIN ASSEMBLY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22951:SF5">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-BINDING CLATHRIN ASSEMBLY PROTEIN LAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07651">
        <property type="entry name" value="ANTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89009">
        <property type="entry name" value="GAT-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AP180 N-terminal homology (ANTH)" evidence="2">
        <location>
            <begin position="21"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="194"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="494"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="202"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="502"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="514"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0018033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="534" mass="58396" checksum="86DCFD9FE38BB533" modified="2023-09-13" version="1">MEKAVLGATKPKCMYPKQKYLDSGHSATIRTYAAYLIEKVHVFGELQRDPVRTGVEGRDGYLRTLPLSKGLLHHVSCLQKQIGTLLACKFYVDELSNEVTIGAFALLVQDLLRLFQAMNEGVINILQHFFEMGKDEARLGLKMYKVFAEQTTKSMEYFSVAKRMEAIIHINIPQLKHAPLSLVRTLEEYVNSPDFEEEQKSAAKTKSVTPSKSTVKSPTPKSPVTTKPSAKDDDDPWSPKKTTEESKQSSSKKDMIDFFSSIDNEETTIQQTSDTFQAQMLAGNDFQQFQLQLQQQSQLFQMQQMQAEQNMMLQNQFTGMAGSQNFQPNMLAAQPTGFNTNPFSSGQQQPGLFQNNMSNNGSMVDMMGANSMNNGGMNSIAPQNTGNPFRLGPSAIGSLPTPSMPMMTGSNHFNTMPNLSSHTTGATNPFAPSTNPLNPFSPNFGKVPAQPTGMMGMNNSIGSGMNGGLNAGSDPMGGMNNNLFGNNSANNNNNMGNMGMMSSQPTGLNGNPWGQQQQPQQTGFGHQGQGSSFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYW4</accession>
    <name>A0A9P6MYW4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006493</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000320">
        <property type="protein sequence ID" value="KAG0018973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYW4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3180">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="300"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="355"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="427"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="220"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="309"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="368"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="389"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="401"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="433"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0018973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="468" mass="51962" checksum="A482F7D46A807525" modified="2023-09-13" version="1">MAFSGTGHRLGDGEWDATGTGTTLAPGVGAVPTLKDICLSTLDRYIDLLEDIGSTPYYLIESVLRKCNVKQLTRVELHTELFERNGRIMTEAGYGGRNTMYDIDHWDFLSMKQEDEDKLARKRELLRQSYSQHDKFKQDRRVIMDPNLRLPNRMRTSSSSNSWPSTAPKKKSLFEKARIEARKVAQMYSSNPYPPPRSRTNSSNNDGIHARTSSGRLMASESGTSSTSSNARRVLAPTRPSASHNTHIPLGSAASRNDSALAARDAVVNGLSLPAQLSTSTMASRGKRYSYKSRPVVYTPLSRSMPAQSPENSTSPTSTSPMSTRAPAGHKLITPSAPGAIVNFFKEINPAHSHATASYRNQDEESSRSPSSPIHQPSKTIQMLREDAGTTTRYHQPSDQLPRKRGDKGKLIVDTKNKSDFRWLEEDDDDEINDHGKTEKFPHKSPANKTPLSLEEAGRQFFNQLIGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZ00</accession>
    <name>A0A9P6MZ00_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">R3H domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_008068</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000427">
        <property type="protein sequence ID" value="KAG0017650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZ00"/>
    <dbReference type="OrthoDB" id="434258at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12253">
        <property type="entry name" value="RRM_PIN4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.50">
        <property type="entry name" value="R3H-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034186">
        <property type="entry name" value="PIN4-like_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001374">
        <property type="entry name" value="R3H_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036867">
        <property type="entry name" value="R3H_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01424">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82708">
        <property type="entry name" value="R3H domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51061">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="183"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="R3H" evidence="5">
        <location>
            <begin position="357"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="143"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="419"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="284"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="75"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="94"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="143"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="425"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0017650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="565" mass="63439" checksum="16401E084CFF7067" modified="2023-09-13" version="1">MNFDAMSIRDNGPASPIDQHQQQSYQQHQRRYSQYGSERGPASPLTRKPTNGGGAGNGMNGYQSQRNSVGMAMNGGQSINGNQSLNGKRHSHSNRMSLASVNWSPPQPSPIQSPVLQQDPRQQQYYQPQAYYQPMMQPGPILGQFQPQPYTQPPQHMQHHQQLQPQQLQQQQLGEEPVDTIPTAIVIKNIPFSVKRDSLLAILDNLDIPKPYAFNYHFDNGIFRGLAFANYRTAEEADLVFHTVNGFDVQGRKLRVEYKKVMPAAEQEKRDQEKAAAAALAAQEALQRREMEIMEAHLQEQQERQERQRELMELQSREFDRTRNRASTALLERRDSGRSLLDREDSSASLNQLDLNDGETLAFYDRLLMFRGDNTKDDMIFPENLSARQRRILHLIADKLSLYHFMEGEGNLRRLIIMKTPPPNSSLESSGNSPGPGTPTKQRPMSFAGRGSLRSESPIYKSRSPLQDISSSSAIGSNSITTTASSALPSSYATYTSTTRSTGSSSPTRSLYRKSMVFDAAAGSSVANANLIYPIRQPKGPEPGKVFTIREQKQLRDATMIKSFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZC7</accession>
    <name>A0A9P6MZC7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_006670</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000330">
        <property type="protein sequence ID" value="KAG0018833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZC7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="134"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="178"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="281"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="344"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="368"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0018833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="379" mass="41947" checksum="BA9EE4DF09D19D3E" modified="2023-09-13" version="1" fragment="single">MIRIATAVYTSRRNLKSVANQPLDYVVVEAPTSRPSSPPIQSLPITEILQPQEHITERQSGHVHLSSRETPTFASRGLDIPAIYGGSAQTESPFNNPQSQTQDDPQSARITTPNVIGVSHSESIAILRAKERPFFVAILRQSLYPITISLSGCLQIIADLTLIDPNNYNSTFGYVSNVATSIQGFLFFLVFMFDPAMIQTRKQWRKYWIWRYYIEFYYGLGMPQEGRNFGDRFMEKCRSLNQYGNETKFDELTKPPSYSWTLQDLNTVTPDFQTTHPLANPFPNTTLNTAPGIAFSPQSYGASSSGGRRGSSRRVLNSDGHGVGYLSTSLSKTREGGGLYLNPSPGSTSNNGEGSSPVESISMGEKLSNNNNSNDTNNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZI5</accession>
    <name>A0A9P6MZI5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aldose 1-epimerase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_005415</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000267">
        <property type="protein sequence ID" value="KAG0019687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZI5"/>
    <dbReference type="OrthoDB" id="274691at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004034">
        <property type="term" value="F:aldose 1-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033499">
        <property type="term" value="P:galactose catabolic process via UDP-galactose, Leloir pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018052">
        <property type="entry name" value="Ald1_epimerase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008183">
        <property type="entry name" value="Aldose_1/G6P_1-epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10091">
        <property type="entry name" value="ALDOSE-1-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10091:SF0">
        <property type="entry name" value="GALACTOSE MUTAROTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01263">
        <property type="entry name" value="Aldose_epim"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00545">
        <property type="entry name" value="ALDOSE_1_EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0019687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="523" mass="57844" checksum="691EF7373B33DE5A" modified="2023-09-13" version="1">MPVKTTTFQTSPVLVQQHNLSIELDSALDSKVNIPPKARVISATILTFGAALTHLTCFDRWNQPQDVVLGFDHWQDYLAQAEPGALNPYFGSIIGRTASRIARASFILENQQHAPSTGEYGRKKLGSVSETYFPFSTSLPDQSVHALKVSNGVDCHHGGPCGFDKQHWTTICTSDAEQKEDDKNECEPFVTLQLVSPHGQNGYPGRLVTTVKYQLTKLGELVVEYWARLETDSASNSTKDEEFRQLDLHSTIVSLTNHTYWNLDGVLNPHDNQFQDLIGEEEVNPLVIQNACSVKDHTLWLGTSKLVELGEQHPVPTGRIFELSKGSGTGAQGDKREILDFSSSSNAKPHKRLGLGLDQIPGGYGYDHVYALGPPASMPQSVSDVGIQGYFPFTPHVATLKSPRTGIRLDISTSEPALVLYAAGYLDQKMLPRTKSRSFGLPTSSSTFFISPSATPLERNDTKLGQEGKSLLINAEMGKFAGVCLEPIRYPDAIHHPDWRNMVILHHDQVYRQKSVYKFSVEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZQ6</accession>
    <name>A0A9P6MZQ6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HCP-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005074</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000252">
        <property type="protein sequence ID" value="KAG0019923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZQ6"/>
    <dbReference type="OrthoDB" id="2384430at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052945">
        <property type="entry name" value="Mitotic_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43628">
        <property type="entry name" value="ACTIVATOR OF C KINASE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43628:SF1">
        <property type="entry name" value="CHITIN SYNTHASE REGULATORY FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0019923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="504" mass="55591" checksum="75B78F7E79B57F0E" modified="2023-09-13" version="1">MSEAKPPGYPQAFRLLPNDALSTQPCSQSDIVSIKPRFDSKTGDYIILWNDILMTFKNASHIRNNGVAVPFLTDDNFEFLKPLRISTHPGIVLDVVLEESPKTDLSVESLRISDTPNQPPRSTTPSNSTPPPVTPSSGNQEQRTTRAPQYRGDSLDTKTTSPAVARSPQFIPEDYVSKDNLYAYTQPPTVDNDGQGGVSQKEIVTAYKEGLSYYYGDGVTQDYFRASTFLIKAANLGHASAQRLLGLMYRYGKGVPQSYPKAFEWYYKAAQQGHAEAQREVGSSYRDGFAVAQDYSKAVEWYLKASENGDVAAQVNLGSLYAVGRGIPRDMTKAMEYFLAAAEKGHAYAQHNIGVSYYNGNGVKQDYSKAVEWFTKSADQGNADAQCNLGLAYHSGKGVPVNYSKAVEWYTMSADRGNPRAQRSLGEMYQKGQGVPRDAVKAFELTRKSAMQGNAFAQNLIGNMYYNGEGVQRDHAAAIDWWSKAAKQGNTTAQTNLQKFSWSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZS4</accession>
    <name>A0A9P6MZS4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Poly(A) polymerase</fullName>
            <ecNumber evidence="11">2.7.7.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">PAP1</name>
        <name evidence="18" type="ORF">BGZ80_006771</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Polymerase that creates the 3'-poly(A) tail of mRNA's.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>RNA(n) + ATP = RNA(n)-3'-adenine ribonucleotide + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:11332"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17347"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="ChEBI" id="CHEBI:173115"/>
            <dbReference type="EC" id="2.7.7.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="13">Binds 2 magnesium ions. Also active with manganese.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the poly(A) polymerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.19" evidence="11"/>
    <dbReference type="EMBL" id="JAAAID010000336">
        <property type="protein sequence ID" value="KAG0018762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZS4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990817">
        <property type="term" value="F:poly(A) RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031123">
        <property type="term" value="P:RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05402">
        <property type="entry name" value="NT_PAP_TUTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.460.10:FF:000002">
        <property type="entry name" value="Poly(A) polymerase alpha, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.590">
        <property type="entry name" value="Poly(A) polymerase predicted RNA binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011068">
        <property type="entry name" value="NuclTrfase_I-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007012">
        <property type="entry name" value="PolA_pol_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048840">
        <property type="entry name" value="PolA_pol_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007010">
        <property type="entry name" value="PolA_pol_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014492">
        <property type="entry name" value="PolyA_polymerase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10682">
        <property type="entry name" value="POLY A POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10682:SF10">
        <property type="entry name" value="POLYNUCLEOTIDE ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04928">
        <property type="entry name" value="PAP_central"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20750">
        <property type="entry name" value="PAP_NTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04926">
        <property type="entry name" value="PAP_RNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018425">
        <property type="entry name" value="PolyA_polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55003">
        <property type="entry name" value="PAP/Archaeal CCA-adding enzyme, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81631">
        <property type="entry name" value="PAP/OAS1 substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 11" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7 11 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Poly(A) polymerase nucleotidyltransferase" evidence="17">
        <location>
            <begin position="13"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="Poly(A) polymerase central" evidence="16">
        <location>
            <begin position="201"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="Poly(A) polymerase central" evidence="16">
        <location>
            <begin position="234"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="Poly(A) polymerase RNA-binding" evidence="15">
        <location>
            <begin position="320"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="390"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="476"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="398"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="507"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="210"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="228"/>
            <end position="229"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR018425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR018425-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR018425-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF04926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF04928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF20750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAG0018762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="523" mass="59216" checksum="F807FA5BF8EC0478" modified="2023-09-13" version="1">MNANQNGKPQRLGVTMPISEAYPTKEDEESTERLRKTLMDQGLFESEEESKRREIVLGKLSTMVKEFVYVISLRRNLPESSAREAGGKIFTYGSYRLGVHGSGKHVQREDFFGELHDMLRRRPEVTELTAVPDAFTPVIKMSFSDIPIDLIFARLSLTSIPDNLSLSDDSLLRNLDDRCIRSVNGSRVTDEILRLVPNIQSFRLALRCVKLWAQRRAVYSNMMGFLGGVAWAMPWPQPVLLKPIEEGPLQVRVWNPKLYPADKAHKMPIITPAYPSMCSTHNVTDSTKAVMLSEFKDAAELVNRIMVERAPWSDLFAKDDFFSRYRHYLQVIASSDSEERHLRWSGFVESRIRHLVTKLERVENLILAHPYIKGFSKVISYKTAAEKEDAAHGIVHTSPADQSDPASDSAETQTMYTSIYYIGLCIPAREAGSTGHRKLDLFRPKEEFTEIVKSWDKYDAQINHASLLSALPPELTEGVDQKKTKRAKSGKKSAVDNRPPTKKRRGSNSQNGALQDSTESIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZU3</accession>
    <name>A0A9P6MZU3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Probable cytosolic iron-sulfur protein assembly protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">CIAO1</name>
        <name evidence="3" type="synonym">CIA1</name>
        <name evidence="5" type="ORF">BGZ80_006689</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the WD repeat CIA1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000331">
        <property type="protein sequence ID" value="KAG0018819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZU3"/>
    <dbReference type="OrthoDB" id="284782at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097361">
        <property type="term" value="C:cytosolic [4Fe-4S] assembly targeting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000136">
        <property type="entry name" value="Probable cytosolic iron-sulfur protein assembly protein CIAO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03037">
        <property type="entry name" value="ciao1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028608">
        <property type="entry name" value="CIAO1/Cia1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19920:SF0">
        <property type="entry name" value="CYTOSOLIC IRON-SULFUR PROTEIN ASSEMBLY PROTEIN CIAO1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19920">
        <property type="entry name" value="WD40 PROTEIN CIAO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="10"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="59"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="106"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="151"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="195"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="254"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="323"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0018819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="362" mass="40366" checksum="596D5822BA9F4D2C" modified="2023-09-13" version="1">MPRLEQLAELQGHEDRVWCASWHPTKPILATCSGDKTVRIWQATNAQDPTKWQCVNVLEGGHKRTIRSVAWSPDGRQLATGSFDATTGIWERDEDESGDYECVATLEGHENETKSVAWSKSGALLATCSRDKSVWIWEVEQDNDFECLSVLQEHTQDVKMVAWHPNEELLASASYDDTIKIWRDDDDDWYCSDTLQGHESTVWAIDFSPEGNHLVSASADQTLKIWQRFEPGNPLGIVTPRRGEPVWKCVATVTGQHDRCIYSVSWSKTHGFIASAGADNTIRVFEVSSASAEAAGRLAEDQQKALNEPGVLLEAKLVTETKNAHGTSDINSVAWYPNEEHGDWLASGGDDGTIKIWRVVKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZY9</accession>
    <name>A0A9P6MZY9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ras-GEF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_005620</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000277">
        <property type="protein sequence ID" value="KAG0019546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007265">
        <property type="term" value="P:Ras protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.840.10">
        <property type="entry name" value="Ras guanine-nucleotide exchange factors catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008937">
        <property type="entry name" value="Ras-like_GEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023578">
        <property type="entry name" value="Ras_GEF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001895">
        <property type="entry name" value="RASGEF_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036964">
        <property type="entry name" value="RASGEF_cat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113:SF368">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113">
        <property type="entry name" value="GUANINE NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00617">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00147">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48366">
        <property type="entry name" value="Ras GEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50009">
        <property type="entry name" value="RASGEF_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ras-GEF" evidence="4">
        <location>
            <begin position="1091"/>
            <end position="1332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="235"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="363"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="478"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="580"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="676"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="718"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="767"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="834"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1290"/>
            <end position="1330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1388"/>
            <end position="1407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="410"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="478"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="580"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="676"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="720"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="768"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="856"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1307"/>
            <end position="1321"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0019546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1503" mass="167591" checksum="F47D6B85AA92B287" modified="2023-09-13" version="1" fragment="single">ATRYQIATSILQPPEPNLTDVAQPTVRTPTNISLLGEPALSTIAASAAGSPNPTLDNSSSGPQLAESNKILISKLLSLSNNFKGAIRTLYEQQNEKVLRFDDYMILDLLMRWEQEADKEVPDPELKDNIATSLVTLGATNALERYQITVGRVWEETEVILSSIRKIRDLVELGRIYHHNDFDADDSEEDAVERDEEAKRTLYSTLLYHANGLVTVLGEFLECVSGIQRLVGTIKTQRKSSDGDQDDVSLSNRRPASEYNYGAQDTAMNFLSDEPRPIKHLDLALMRKLKRKTPFKSIADKVRRSFSDFAKRSTNQLLTIFPPLGDGTNDGFNWDSYSDNEYDSEEWAPTDMDSSVIGDEDAYTLALSPPDSPSVTSEKPRHQLHRRLSSKDSSGQPEQYWPGSIRVGLSDDSQSPGNPSSPVTTFSTTGTVIGGQTMAMSRSRSSERSVDAINMRFIPGPDTPPVPKLPETASYFPIAPESPASPSPSAKERRRSVQLFRKNSQASNIKGAYISSPIPTAPRPFSVYSSGSESQTPSRHNYRVCPPKPPTALPPMPPMPPSTIHSSSYFKADEIMQDSANFKRQPSNKQANSYLATRSTSPQQATPPTLESHFVRRTSIRMANRKRYSIKMPSDEVSDQEVADINNIPSTVFWRRRSYNDALEKSWQALQLETLNSNRSENSVQSTPVTTEFAPGSRSSVRLSSFEFSIPYGPKDPKFNRLSSRSISSSPRSSLYSKYDNRRHSSPLTPSAENALTEALSHRASVPFRQSMQSSSPMSPNNRNSISMMSTLNEDTAHKRHIPRPSRSIDQLNFVEVDSLNIPVRTRLYQRDSSFEGARINSKSPMQDSKDSRENDVQPTPETPQQPISPSRYNDMKRAWEILNLDVKRVNQYSDLRAYAKINNVQNNSWAYSHPNAHQSTSRPHAIVIREKGEDVLILEKMDERLQVVAGVLENLIERLADQNEQDGEYIQFEDFELNQELLKTLRKFLEGDVRKCGFVIEADCIEKNITIRSRSPKKNCSVIMEQGRFCLQRTRTRKISISKSQSRLQSPTYLGLMTTLMEPTPALPMEQTSEYGHPPDLLSTSPILSLTALELARYLTLADMKAFRCITVFELMSGWWKRRRSAESKNADDAEGSEHTDDGAIEAFTRRANMLSYWVAHEIVSLASTKHRKQLIKKFIEVAKICRDLSNLHTAMFIISALISPPVRRLHASWKMVSSTDMETLRQLEKLFDFSGNMRYYRQIIGEAQAPMIPFLPILLKDITFILDGNPTMTTSKSYVDQTPLPVSGTATAEAEAVSTGPNAEVSSETSTSSLPTSPEKSGTDADKSSAEKGLLVNFEKFRQLTQYVENAVDMAKCLDYWFEPQLLRQAQVFRPIHCSTSNDTDSIYGSISSGRGGSNSPLDSSRGALDHVSEIVEHRLVKASGLYGAPQKVVEVEFSSKPKNTSLWKGVVNVGGIVSSGLGSGGSNICTNGSSVSETVIRAVQGEEEYLMGLSLMCEPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0E9</accession>
    <name>A0A9P6N0E9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_004100</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000213">
        <property type="protein sequence ID" value="KAG0020497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0E9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051615">
        <property type="entry name" value="Transcr_Regulatory_Elem"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313:SF81">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="10">
        <location>
            <begin position="13"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="66"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="182"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="625"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="853"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="966"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="880"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="66"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="82"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="140"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="182"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="200"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="629"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="654"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="678"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="765"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="858"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="966"/>
            <end position="979"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="987"/>
            <end position="1000"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0020497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1100" mass="121931" checksum="040A78B68D08BECD" modified="2023-09-13" version="1">MTKIKPRLIARISCQECRRRKTRCNFDGQSQKCSTCARIGTPCIFSQKNGVILDIDKVMEENNPHLLHQREKEQRAKERAKLSAISPSTSSSSSSTLHSTLAPAPVPNTSIYSKSTPSSSYLSGARFSHNKPNRSNSILSASAGHSGRSSSNEETEELSSVLDRLQIDAFGIAPHTLRSFSQVAGDNDSAQVSAESSETESEHPHKSEAHDEAKPTLNKRNSTGSGCHRSSRSRSLPLVDIQPDLIDLYFKHIHPYLLVLHKPSFFRRLHDPRDPVPDFLLAAMYAVASHYAPGREQDGRQYFEFWLSRLDDALDKPRLSTIQSLLMVIKYQEGVKSTGFYFRTYMYTQMVIVLARELQLHKTTPVNAKLDPESHEVRRRLFWAIFVLDQFLSVSQGRTMSFREVEPEADLPRTDNEDPNDLEEIEVIENAVEYIKLVKIDHQALILVRKFLTKVVTPEETIPQGLFLHQAMLAWKANLPARLQMAPNMTARNPFVAMLHVLYHACAIMIQRCYCEDPSVSHLEVSTVSRNTCIVAATNITIIIDDVYTNYGIVPMTYPLRGCYFVIYCLIAAATIQVNDIRNGGNGTVMFKRSLTLLNHLLRKSSAVDISKEVEILKNSMDTTTDGFSTPVSSSSSTPHYDHRPPLKPILPMSQKYSSKLNFSSSSVTPIRPRKISPKANSSSSINSNYSSTGNSAQTSRSSGSNQTSSSSQQSSQGATPAYSSPSSSSLCGSKGSSDQAFDSSSQSPNSSVAVDDDLDITIKSSPSPDLSSRSISICLSDSNNDDASTSTPQVGTEPYLQSVPTFTAPASLPSDFNAFALAQQAARGGNHNPPPLMSLTQFLAFQQEQQRLDLRKQQQAPASTSLDQMTASQIQVQHLDNQQGQAMQFQQQQQQQQQQQQQQQQQQQQQQLLQQDPALFNSFLNSFSNLGNYQQLNSDQAQSELLSMLDSSMFNYNNNSDSFGLASSTGPTFMPQQQQHHRHQDSISSISPTSTTISSAFSPDTQNSFGSFFLSSNEQNQQQQQGTAISDETLLANSALERNHLQDTPSPEAFQVLDMTSSFPSYIGSDNSVPFGVRQNISDVEKIFKFQAEAELTTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0H4</accession>
    <name>A0A9P6N0H4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_004786</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000240">
        <property type="protein sequence ID" value="KAG0020096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0H4"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047146">
        <property type="entry name" value="Cyt_P450_E_CYP52_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24287">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24287:SF5">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7 8" id="KW-0408">Iron</keyword>
    <keyword evidence="3 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="458"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0020096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="513" mass="59140" checksum="8B9AEA9C6CFA1603" modified="2023-09-13" version="1">MKRSRANPGMAMLALTAILYFWLGRLRAGRKPPPRGVAVPRLRTRFSMVDVAYQYIKARIEGNELQWVQGLSKQGLTLTTEAIGHCLIVAFEPSSVQHMLVKNFENYPKGPTFHKTLFPFLGTGIFNSDGAAWKNQRALARPHFQVTEYKGAVHIEAQINKVFGIIDEVIATGGGKEAIDVQDLWSRYTMDTSTGFLFGSCINALDVPQSRFMNAFNYTQRVCGWRMRLCDYQMFLPAPQFKQKIREMDEVLMPIVDAAIAKEMARHANDKDSEGEEGGGKKNRQHDNLLMHFLCSADENGRPFDRVYLRDMLMNFLLAGRDTSTNLLTFMCYNLGKHPDVMERVRQEIFEVIGRERKPDHEDIKKLKYLKQVINETLRLFPPVPFNIKTCLEDDVLPNGHFIPGGSLVVHSAYVTHRMKEYWGEDAEVFDPDRWGPERVKDIRPFMYFPFHAGPRICLGQNFAYNQTMNTIIRLIQRYTWKVANGFETKIDSDITMYSRNGMQIVFEEYREQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0Q0</accession>
    <name>A0A9P6N0Q0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Vacuolar transporter chaperone</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">VTC4_2</name>
        <name evidence="9" type="ORF">BGZ80_005433</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000268">
        <property type="protein sequence ID" value="KAG0019674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0Q0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033254">
        <property type="term" value="C:vacuolar transporter chaperone complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006799">
        <property type="term" value="P:polyphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd14480">
        <property type="entry name" value="SPX_VTC2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.100.30">
        <property type="entry name" value="VTC, catalytic tunnel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003807">
        <property type="entry name" value="DUF202"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051572">
        <property type="entry name" value="VTC_Complex_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018966">
        <property type="entry name" value="VTC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042267">
        <property type="entry name" value="VTC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46140">
        <property type="entry name" value="VACUOLAR TRANSPORTER CHAPERONE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46140:SF2">
        <property type="entry name" value="VACUOLAR TRANSPORTER CHAPERONE 3 COMPLEX SUBUNIT 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02656">
        <property type="entry name" value="DUF202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09359">
        <property type="entry name" value="VTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="646"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="670"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="domain" description="SPX" evidence="8">
        <location>
            <begin position="1"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="491"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="589"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="510"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="529"/>
            <end position="538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0019674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="722" mass="81601" checksum="2EF7401759813D3D" modified="2023-09-13" version="1">MKFGDNLENSIYPAWKEYYVQYNVLKKQLEDGVSKPAGWTERDEGIFGQTLDTDLTKVFNFTNEKFEELLERTTKAELQTATFQESYDQKAALTSTISDITDEVNQLSKYCRTNYAGFLKIVKKHDKNVPYRLRPVFMVQLKSRAFYDVNFDSLIVRLSKLYHILGAESLPLPFGTPITPSVLTAMAAQEGIDRRSFKFWVHPDNIMEVKTTVLKHLPVILYTPRGPNKTESFDPSISSVYLDNSSFDLYNNKLERKEGAQAIRLRWYGSPTNNEISVERKIHHEINKFGEYHDRFTIKEKYVDAFLKGEYTMDRQIAKLREQGAKSATEIAQFEEMVKDVQNVIVDMKLKSVLRTIYNRTAFQIPGDKRVRLSLDTDLCMVREDNLDNVTRSGSHWRRMDVDYPMLPKTAYEQDMARFNYAILEIKLELPVGKSAPSWVDELMNSNLVESAESFSKYVHGVAVLLERHVALLPFWLAQLEKDSVRTADSMRGHLPTDTPSLSRAGSTYEIQSINSRRSSIASRSESEGGTSTRPSSKGKQKSMDIVVDSNYGQNGGQPGYGSTSKPASRASSVKKSFGFKGFGGVFKQSGKSKDSRDTSPLLGPNDGNGTVPQIKIIPPKPKKVVGPLKVEAKVFFANERTFLKWMNFAVLLGTLGIALFNAGDSIGRFAGILLSITALATLIYAIWLYERRLDMLRNKDPGPYDEPLMPTLMCSSVKSKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N125</accession>
    <name>A0A9P6N125_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">3-oxo-5-alpha-steroid 4-dehydrogenase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_003797</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000202">
        <property type="protein sequence ID" value="KAG0020683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N125"/>
    <dbReference type="OrthoDB" id="541710at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003865">
        <property type="term" value="F:3-oxo-5-alpha-steroid 4-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006488">
        <property type="term" value="P:dolichol-linked oligosaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016095">
        <property type="term" value="P:polyprenol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001104">
        <property type="entry name" value="3-oxo-5_a-steroid_4-DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039698">
        <property type="entry name" value="Dfg10/SRD5A3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14624">
        <property type="entry name" value="DFG10 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14624:SF0">
        <property type="entry name" value="POLYPRENOL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02544">
        <property type="entry name" value="Steroid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50244">
        <property type="entry name" value="S5A_REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="24"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="101"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="170"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="208"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="353"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="3-oxo-5-alpha-steroid 4-dehydrogenase C-terminal" evidence="6">
        <location>
            <begin position="265"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0020683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="411" mass="46819" checksum="81406C3C560E562E" modified="2023-09-13" version="1">MHDHQHLKTAGDPSTWIPSFSQLIQLYFVIITATAFLAATLPFLRDSILSYGKLDYPSSTTNTATATNASPAQKKPLAATPVADHGQFFVVLKTLRVPKTWFAHFYVFATLWMVYLSLDLLVYTLSSTSSTSPVLQIVPSIFISTYPSWSFLTLLNLLGIMPSHPHSLSWTPPPALLLAMSCYLIQVVRRWYESWFVERPSPQATLHIGHYLIGITFYAAMAPAIWVDTYESWVKSTVLQNQTDQHEHQSQHAIEHENLFGSLPLQTWIGFALFLWGSLHQYRCHVILANLRKPSSREASAGVQRQQEYKVPFGDWFQYLVTPHYSAEMVIYLGLYLMVSSSLSLSTSPTVPTMLYSWVWVIVNLGIVARETDQWYRTRFGDNYAEPKETVTGQQRQPKTARRAILIPFVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N194</accession>
    <name>A0A9P6N194_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Adhesin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_002501</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000162">
        <property type="protein sequence ID" value="KAG0021386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N194"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="331"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="331"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="366"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="380"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0021386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="447" mass="48740" checksum="7A07282CF27EC56D" modified="2023-09-13" version="1">MGLFSKPLLSAHFENEDVQISAELCPNISVKVVGRAKGDITILSGNEDMVQIHTSVQAKEVLIKNAAALEPIQDGDQYTYTIHTPLEEKLEKAVTFQVFITIPRHLDSLESFKIEGHHIEVAVGNIGHTFIRKLEIANIKGDISIDNFYGECATISSAQEGGIKGKFSVARLNTSTKSGRIISSAHLLNTDDQQPPPKVICQAMNHCIDLKVDGTDLFGPFSVEAKTQVAPLDVKILLSSEDQRFLGNFINFGGVSRVLLSDNYQGRIETRTHYGKIFIDEPRFVRLKDAMLSVPSKSDRDYYNHLAGDPMAAPTPGSSSLLSSMSHISNKITSKGSSQGTTMSLSDDHPSHHRRHPSTRSQNRQPSSPGSINSSGSNSRAESTTGSYLDNMSPPASPVSPGSDRQKWIEDKDKDSIITRELIGTVGEGPGLVICKNSSEDIFVKLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1B3</accession>
    <name>A0A9P6N1B3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ACB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_002246</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ACBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000155">
        <property type="protein sequence ID" value="KAG0021507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1B3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000062">
        <property type="term" value="F:fatty-acyl-CoA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.80.10:FF:000010">
        <property type="entry name" value="Acyl-CoA-binding domain-containing protein 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022408">
        <property type="entry name" value="Acyl-CoA-binding_prot_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000582">
        <property type="entry name" value="Acyl-CoA-binding_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035984">
        <property type="entry name" value="Acyl-CoA-binding_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014352">
        <property type="entry name" value="FERM/acyl-CoA-bd_prot_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23310:SF62">
        <property type="entry name" value="ACYL-COA BINDING PROTEIN 1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23310">
        <property type="entry name" value="ACYL-COA-BINDING PROTEIN, ACBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00887">
        <property type="entry name" value="ACBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00689">
        <property type="entry name" value="ACOABINDINGP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47027">
        <property type="entry name" value="Acyl-CoA binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00880">
        <property type="entry name" value="ACB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51228">
        <property type="entry name" value="ACB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACB" evidence="3">
        <location>
            <begin position="3"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0021507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="87" mass="9729" checksum="C268149FF3BBC56A" modified="2023-09-13" version="1">MTTVAEFEAAAAEAKNFKTSPTQDELLKLYALYKQATVGDNTTAAPGMFDVKGKYKWNAWNELKGTSPEDARKQYVELVTRLATEHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1R6</accession>
    <name>A0A9P6N1R6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GTP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">RHB1_1</name>
        <name evidence="3" type="ORF">BGZ80_002498</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000162">
        <property type="protein sequence ID" value="KAG0021383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1R6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020849">
        <property type="entry name" value="Small_GTPase_Ras-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24070">
        <property type="entry name" value="RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0021383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="91" mass="10185" checksum="C61E46DDCA09E728" modified="2023-09-13" version="1">MIGVIRDKILNFTGTDWVPIVIVGNKTDLQGQRQVSREDGEELAARWKCLSCETSAKTNMNIGRAFELMIAEIEKSTDQVPEEKKGECSIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2R5</accession>
    <name>A0A9P6N2R5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_011237</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000088">
        <property type="protein sequence ID" value="KAG0022757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N2R5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052982">
        <property type="entry name" value="SRP1/TIP1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40633:SF1">
        <property type="entry name" value="GPI ANCHORED SERINE-THREONINE RICH PROTEIN (AFU_ORTHOLOGUE AFUA_1G03630)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40633">
        <property type="entry name" value="MATRIX PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G05410)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040229711" evidence="2">
        <location>
            <begin position="20"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="346"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="356"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0022757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="436" mass="45629" checksum="E6B56F1A96DA267F" modified="2023-09-13" version="1">MRSVATTIITLIMSALTTADTTFQVFITDPSSSTVWIAGRPAIVKWILSISPPNATLTGSLPVELVGGKSLTDLDLIAVLGSGSFDANSLIVEVPDDANRGPDYVYSVRFGEGSYSELFTIKGPIIIGDPKPKITATKTPTTYTFLTTTQTNKTTKTASTINIQTSTTKTKSSSSTLSDTTIRTFLPTITMQFPAPPTTPMFPTFTSLDISPSLTSAVPLIDGPSTDSIPMSNNKNVVMRFSTFSIAAIATLASTVLAQVSPSHPRQGDIWILGRQVTMYWSPRPTTDLPIQLLTGETLTAQKVVADLGTAKADTLSLTIDVPDEPVGWYTVRIGTSYSHVFAIQKDSTTPPTTPEPTEASNATTTANASATVTGVPTANATGATTTIALPTYSSSSASAKSTTAASTSAASYLKVANVMPLVAVAAATFLSSMAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3V0</accession>
    <name>A0A9P6N3V0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Protein with SprT-like domain at the N terminus</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BGZ80_007979</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Spartan family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000042">
        <property type="protein sequence ID" value="KAG0023797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3V0"/>
    <dbReference type="OrthoDB" id="5236983at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031593">
        <property type="term" value="F:polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006642">
        <property type="entry name" value="Rad18_UBZ4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044245">
        <property type="entry name" value="Spartan"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006640">
        <property type="entry name" value="SprT-like_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055220">
        <property type="entry name" value="SPRTN_ZBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21220">
        <property type="entry name" value="DNA-DEPENDENT METALLOPROTEASE SPRTN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21220:SF0">
        <property type="entry name" value="DNA-DEPENDENT METALLOPROTEASE SPRTN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10263">
        <property type="entry name" value="SprT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22934">
        <property type="entry name" value="SPRTN_ZBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00731">
        <property type="entry name" value="SprT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00734">
        <property type="entry name" value="ZnF_Rad18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51908">
        <property type="entry name" value="ZF_UBZ4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7 15" id="KW-0227">DNA damage</keyword>
    <keyword evidence="12 15" id="KW-0234">DNA repair</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <keyword evidence="8 15" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="UBZ4-type" evidence="17">
        <location>
            <begin position="451"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="218"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="354"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="422"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="238"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="259"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="291"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00030396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAG0023797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="482" mass="54248" checksum="F68221CF6AD15602" modified="2023-09-13" version="1">MEQSDEEFARLLQEQEYMNAAGNIDWQGDTSKTSITIPDDDADVQFGHDIEAPFKDLHQLFLVFNDQYFESKLSACEVRWSPRMTRCAGLCYYQSKAQYCSIRLSEPLLKFRPESDYIDTLLHEMIHAYLFVTQAIQDHDGHGADFQYHMNRINEAAGTSISIYHTFHDEVQHYQTHVWKCNGPCRTRPPYYGIVRRSMNRPPQPADKWYAEHQGKCGGTYTKISEPEPTKKKTSSKSQKDSKQESESKERTLMDNYFSVSKSPESASPSSSQASPPQRKIKRRGSNTTEKSIHGDHGHIEKKGHSISDIAKPSTIVIDPDSEECDDRPPPRVAAAAAALERFERNLRLKNLSSTIKPEPLQSKRREPGFAGRIEIDDEKSKRIKSEGSAPIEKTQPGVIAVKQEGNGLSARSKSQLIGTKAQPIKLEDNDTSHVGSNPPSVAVDADAVPRVQCPICSVEVEERTINDHVDLCIWRSSGNSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4H2</accession>
    <name>A0A9P6N4H2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Bromodomain and WD repeat-containing protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">BRWD3</name>
        <name evidence="8" type="ORF">BGZ80_009799</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000062">
        <property type="protein sequence ID" value="KAG0023305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007010">
        <property type="term" value="P:cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052060">
        <property type="entry name" value="Bromo_WD_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057451">
        <property type="entry name" value="BRWD/PHIP_AD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16266:SF17">
        <property type="entry name" value="BRWD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16266">
        <property type="entry name" value="WD REPEAT DOMAIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25313">
        <property type="entry name" value="BRWD_AD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="15"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="57"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="252"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="439"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="domain" description="Bromo" evidence="7">
        <location>
            <begin position="1072"/>
            <end position="1142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="197"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="340"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="621"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1170"/>
            <end position="1372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="220"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="354"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="621"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="645"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="669"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="698"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="722"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="760"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="781"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="823"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1188"/>
            <end position="1221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1231"/>
            <end position="1247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1248"/>
            <end position="1259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1275"/>
            <end position="1284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1288"/>
            <end position="1306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1311"/>
            <end position="1320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1353"/>
            <end position="1362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0023305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1372" mass="153838" checksum="F1A58C5BB3C51BC9" modified="2023-09-13" version="1">MPRFVPSLFQELVVMNGHRFPTYCILFDRTNSRIITGSDDYLIKIWSAQSGYLLFTLRGHSAVVSYIDLSTDNTMLATASHDGIVRVWDVKTSAPVAVLPTGTNPRNRKHLTTVSFSPSPIPQIRYLIATSIDGYTWVWKYDRDTKKFQTPPTMLDCKTFNDSKLKCSTWNLTGSQFAVAGTDLFIRVFSTIQGGPEAIKNGKRRKSHDKSKAGQEGTADGSSSNANATGGPSSSSNFSKQNWGDPVLIAQLDGHSGVVTSLSYSRHGNRLLSGSVDGFVRIWKYDQQSKMWTSMAIDVRDEHTQADATITAARHMMPSPVTGSSLPNPFLVEASASNTTNNETTNADSGMNDSTSANQTQTSSQPGTDADPRPTEPSAEDSRIIPTMAIWSLDDSAVILTTSLGEIKIFDSTTGGLIHTLKGHVRGSSIYVVDVHPYDKNILMTAGYDGQVILWDIAKGTQLNSWTYAEHEFLDGRFSPDGLMFAVTDQEGKCILFGAGMNPEDYKDARSFVEQTFWSDYAPVRYDADHNVVDDTTQIAPHLMERTPILDNNGRDYARQKGPRFGLDLPVALPPGVLEQEEAMKRGLLDRELENLAEQTLAILPTTDKKALYKRRREFILEEEEDDDDPMTTEVPIVPLPNDSSGEDESDDSDLAPEDGVNPVSEFVVNDDDDDDDYAAGSQGSRKRRTASSGGTPRRQRAVIDKRRRGGRARKRMRLRDSDEDDDLDIDGIEYSDESDGYDTPSTTTRGKRSQGGSHGTPSGSKSQRSARPKSFANDDYPSDEALESSGHEDDDEGVFSGSSAGGSFSGVPNFDTSMPMSPKKKKQWRGNGRKKGKAVVRDEKAAELYKWFPSDWIKVNEPRKTPYHPQIGDYVVYFRQGHSIYLKETPLRSKLNLKIVPYIKDTRLPWATFGRVSRITYNVGPPTWCTITLEEQFLTSTFGLPPNPEFTASRRRFEVEFHDLGDVPDFIVLYDVFQEGMNAHYVVGEQIWASFDGSAYPGTISNQVIEDENLPDSMWMAFEISWPDNNEVTNLSPWEIQREEQEDESPQIETIPPEEYERIEEIMQHLLQMDEFQIFKSSVDFEAYPDYCKTVAYPICLESIQERLSSNFYRRSRAVQYDIELLEKNALTYNDPKSGIAMYAKHLSRIFKTSLANYSKPLPSQIFVKRSRNDEDDEFDGSGSENEAVEIESDPEPEFDDEELEDEEDDNAFLDDDSSNDDSRTSSRSRTSHRRSKAGRTSRSNRKSASSSIAAVASPGNGSRKKYTNGNGRGRGRKSRSKRNNSDEEDGDEYNEEEDDDDDDGEWGKRRGGTRRGRRSNAANLDDEADYGQVEERESDEYGNSEDTYSKRPSRNKRKKTQIVDSDDDFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N504</accession>
    <name>A0A9P6N504_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mitochondrial import inner membrane translocase subunit TIM54</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">TIM54</name>
        <name evidence="13" type="ORF">BGZ80_008348</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TIM54 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000045">
        <property type="protein sequence ID" value="KAG0023723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N504"/>
    <dbReference type="OrthoDB" id="5598305at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021056">
        <property type="entry name" value="Mt_import_IM_translocase_Tim54"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11711">
        <property type="entry name" value="Tim54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0811">Translocation</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="226"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="249"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0023723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="395" mass="43241" checksum="B09B635460575491" modified="2023-09-13" version="1">MDNTTAPSTSAATPEARPKLTPNTPKPVPTTFAGKLRAKLPSRGWMIFWGTVGTLGGLVVRDHYLTVDAKKRVADKVDVLSKQSCGVQEMPRKVTVYIMPPPGDGIHKTRHYFKQFVKPVFDAAAMDYEVREASNEGQIREMVAADVRRKRQVAAGKEPALTEQEQNAPLVPMKSVSDGIVVLGRIALGEVLKGYNDGCLQSLDDPEPVVQVESAKEVSLEGEAASLVKEATGSVETTGDNDAKKEESSTAQTTETTPATPEASATPAVAEPVVIPQDEAYFSLPPTGLEPIGYIPFKNLVGFRNFHKKLYALFNSYDCVEYAGGSVMKVAFAETKDMEKDDLEIGRDEEPLFQKYRGPVEIDILDRVRENVKLYVTPQHIPEQKKADGEEENSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N5A7</accession>
    <name>A0A9P6N5A7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">60S ribosomal protein L32</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RPL32_2</name>
        <name evidence="4" type="ORF">BGZ80_005014</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000025">
        <property type="protein sequence ID" value="KAG0024232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N5A7"/>
    <dbReference type="OrthoDB" id="268693at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00513">
        <property type="entry name" value="Ribosomal_L32_L32e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001515">
        <property type="entry name" value="Ribosomal_eL32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036351">
        <property type="entry name" value="Ribosomal_eL32_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23413">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L32 AND DNA-DIRECTED RNA POLYMERASE II, SUBUNIT N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23413:SF1">
        <property type="entry name" value="RIBOSOMAL PROTEIN L32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01655">
        <property type="entry name" value="Ribosomal_L32e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01393">
        <property type="entry name" value="Ribosomal_L32e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52042">
        <property type="entry name" value="Ribosomal protein L32e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0024232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="131" mass="15138" checksum="591E228A5D14A3D2" modified="2023-09-13" version="1">MVTPLKKHTIVKKHTATFKRHQSDRYKSVKESWRKPKGIDNRVRRRFKGQIAMPKIGYGNNKLTRHLLPSGFKKFVVSNIAELNLLLMHNRTFAAEIAHNVSSRNRIAIVERAQQLNIKVTNANARVRTEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SR31</accession>
    <name>A0A9P6SR31_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AMP-dependent synthetase/ligase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008567</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004681">
        <property type="protein sequence ID" value="KAF9992408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SR31"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043041">
        <property type="term" value="P:amino acid activation for nonribosomal peptide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF1">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="1">
        <location>
            <begin position="15"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9992408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="209" mass="22805" checksum="74418E5FE65A5FE7" modified="2023-09-13" version="1" fragment="single">LLDGYLKTSVSSLYTAYVMYTSGSTGLPKGVLVPHRGVVRLVINNGYADIRSDDCFAFVANPAFDASVFDVWMPLLNGARIVIIDRDIYLDPHRLEAAIESHQITSILLTMAILNQYAYIIGSALSKLRFLVCGGEQGLTEVFSEVLRHGGPVRLINAYGPTEMTVIATTYEATDTVGQLDRLPIGRPISNTKTYILDNHCSPVPIGVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SRH4</accession>
    <name>A0A9P6SRH4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004366">
        <property type="protein sequence ID" value="KAF9993326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SRH4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="275"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9993326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="295" mass="31892" checksum="B9CC2A0ACC2F1021" modified="2023-09-13" version="1" fragment="single">SLLGETRVSKYILEQISIVNATVRSFRTGHLLFPTVFPQVLESTGYEYSSSSASNDQNTQMPFQWFYNSAYNQEVDVIEFPLSASDEDGEMNGDFYAPGAGGYPDGSYAWNQYQCIQMMAKYGTQYTFLIHPTSHIVLGLGSTTFADKLAFQQTLTSLVTNVSYFDTMSGRGDFHKARINAGIDVSVFGNVATVTLTLTQKIIDLTLRIPAAWVFIYSTVSVDTSTPGAVILMNVVPAGTVTLKFQTSGTVTATTNPAPGPAPTTTSIDLVSPTIPAPTPTPTNPLTIDDFSNPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SSM8</accession>
    <name>A0A9P6SSM8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_007243</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003677">
        <property type="protein sequence ID" value="KAF9996441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SSM8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9996441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="139" mass="15934" checksum="5BC6FDBA0245C941" modified="2023-09-13" version="1" fragment="single">MALQELGALQDYRIRMLFEQLIVNLPRKEQEEQSEETLVANIVAPILRTFLNHVDDDIFTHFPNTESNTQRKQGLKADKPDFKVVIGDKEASFGEVTGRTQRSNKAKNGWDIYRLVRFGKSVLDEGAPMVPLVQIIYDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6STA4</accession>
    <name>A0A9P6STA4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Ras- protein Rap-1b</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">RAP1B</name>
        <name evidence="10" type="ORF">BGZ80_006343</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the small GTPase superfamily. Ras family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003127">
        <property type="protein sequence ID" value="KAG0000553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6STA4"/>
    <dbReference type="OrthoDB" id="5976022at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000080">
        <property type="entry name" value="Ras-like GTPase Ras1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020849">
        <property type="entry name" value="Small_GTPase_Ras-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24070">
        <property type="entry name" value="RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0488">Methylation</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0636">Prenylation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0000553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="187" mass="21298" checksum="504BAD844CC3C497" modified="2023-09-13" version="1">MREYKLVVLGSGGVGKSALTVQFVQSVFVDRYDPTIEDSYRKQVEVDNQQCMLEILDTAGTEQFTAMRDLYMKNGQGFILVFSIILASTFEELGELHRQILRVKDVDKVPIVLVGNKCDLEGDRKVPREKGELLSQKWGGTPFYETSARTRINVDEVFYDLVRMINRQNPIKVDKSKGNKVKKCAIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6STT2</accession>
    <name>A0A9P6STT2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">tRNA(m1A58)-methyltransferase subunit TRM6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">TRM6</name>
        <name evidence="8" type="ORF">BGZ80_006026</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRM6/GCD10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002977">
        <property type="protein sequence ID" value="KAG0002104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6STT2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031515">
        <property type="term" value="C:tRNA (m1A) methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.330.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017423">
        <property type="entry name" value="TRM6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12945">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12945:SF0">
        <property type="entry name" value="TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE NON-CATALYTIC SUBUNIT TRM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04189">
        <property type="entry name" value="Gcd10p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038170">
        <property type="entry name" value="tRNA_m1A_mtfrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="421"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="421"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="443"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="493"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0002104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="512" mass="57294" checksum="6FB31F07E6DF4A4E" modified="2023-09-13" version="1">MATTITSSDTINAGEHVFIKMPSDNVKCLVLKPNTTVSLGKFGTFKANDIIGRAWGHTYEIYDKDNKTRVYHLDEINEVEETENNNREIIDDGSSQKLSLEEIKALKSEGLKGELTGEEIVNKLKESHATFEKKTAYSQAKYLQKKGKKFHRIFTPIKPTTYSVNEYFYTKNPAKIRDIRMDTLSQLLSYSNVHAGCKLLVVDDTQGMIVSALAERMGGMGTILGLYDGDNPHYDVLKYMNFSQEILDSVKVLSWLRIHRPADETSSISPTNQPTTANQQQILQMTLTGKDLEGYHRRLKAYTIVEEARKILFQADFDGLIIASQYQPESILPKLLPYIRGSRPVVVYHPHKEALLETSTWMRKCPDLLAPQLTESWLRKSQVLPGRTHPEMSTWGSGGCLLTATRVLDQPVQAALTKRERAAMEKKNAEAKKLKREREESENNAASSSSSSSLSVEATPSTTTTTATASTTTTTTTTTTTVLETEVVVESAEAIKEENDGDERAVKRVKQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SUM2</accession>
    <name>A0A9P6SUM2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_005575</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002746">
        <property type="protein sequence ID" value="KAG0004671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SUM2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050562">
        <property type="entry name" value="FAD_mOase_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356:SF2">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356">
        <property type="entry name" value="FAD-DEPENDENT MONOOXYGENASE ASQG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="27"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0004671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="350" mass="39175" checksum="E3C620A1CE19DAB9" modified="2023-09-13" version="1" fragment="single">MSDTAERSPTGNVYGTTYHTPDPSNPKVLIIGAGLGGLTLGILLERAGIDYEIFERARAIRPIGSATGISPNILPLFEQLGLIDELRAIWKEFMSITVYKEMSDGETFEELSKTNNAPIEKLSGYHPVVMSRPGLQNTLLSRVPQHKIHLNKRILDVTQGTDSGVQIRCSDGMSHEGDILVGCDGAYSSVRQAMYRRMKDAGQLPSSDDVDLKVVHMSILGTTNPLDPNVVPFPEDGYGRFHAVLGHEKPYAWRIFETPDNCLCWRIDLQLQSTSFSDNDSFRSTDWGSKSNKKEIKEEWRKFRMPVGSGKTVSLGELIDNTTEENVTKVMLEEKLYTTWYHHRVVLLGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SVR7</accession>
    <name>A0A9P6SVR7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Coronin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">CRN1</name>
        <name evidence="12" type="ORF">BGZ80_004666</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="7">Binds to F-actin.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the WD repeat coronin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002359">
        <property type="protein sequence ID" value="KAG0007427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SVR7"/>
    <dbReference type="OrthoDB" id="1850764at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000197">
        <property type="entry name" value="Coronin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015505">
        <property type="entry name" value="Coronin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015048">
        <property type="entry name" value="DUF1899"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10856">
        <property type="entry name" value="CORONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10856:SF0">
        <property type="entry name" value="CORONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08953">
        <property type="entry name" value="DUF1899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16300">
        <property type="entry name" value="WD40_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01166">
        <property type="entry name" value="DUF1899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01167">
        <property type="entry name" value="DUF1900"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="5 10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 8 9" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="DUF1899" evidence="11">
        <location>
            <begin position="3"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="125"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="168"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="417"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00062568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU280818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0007427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="458" mass="50825" checksum="39409635C5E86F4B" modified="2023-09-13" version="1">MSRFVRPSKYRHVYGTAARREFSYDNVKVSGNAWDTNLIKVNPKFFSLNWNSSGGGAFAVIPLSMTGKISDALPLYRGHSAAVLDTDFSPFNDHLIASGAEDSKVFIYTIPEELGEEDIEPVVRLTTHGRKVGQVLFNPVAENVLLSASADLTMKLWDVEKGAEKQEITGHLEVIQSVAWNYNGTLVATTCRDKKLRVFDVRSNKIVMQGDSHSGVKGSRVLWMGNSDRLATTGFSKMSDRQVNIWDATNLEKPLRSNNLDTSSGVIMPFYDGDSNMLYLAGKGDGNIRYYEYENDELYTLSEFGSNVPQRGLGFMPKRGLNVNECEIARAYKVSNGFVEPISFTVPRKSDSFQADLFPDCIGDEAALTADAWFGGETSNPKLISLEKGFTATTKKEFVASVAAQAAETIVTAPKSDKDYQEAYHKLRQENEDLKNQIAQKDVKIRLLEVQLEQLSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SVV0</accession>
    <name>A0A9P6SVV0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">TFIIH/NER complex subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">TFB3</name>
        <name evidence="6" type="ORF">BGZ80_004825</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002415">
        <property type="protein sequence ID" value="KAG0007312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SVV0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005675">
        <property type="term" value="C:transcription factor TFIIH holo complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061575">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004575">
        <property type="entry name" value="MAT1/Tfb3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015877">
        <property type="entry name" value="MAT1_centre"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00570">
        <property type="entry name" value="cdk7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12683">
        <property type="entry name" value="CDK-ACTIVATING KINASE ASSEMBLY FACTOR MAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12683:SF13">
        <property type="entry name" value="CDK-ACTIVATING KINASE ASSEMBLY FACTOR MAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06391">
        <property type="entry name" value="MAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MAT1 centre" evidence="5">
        <location>
            <begin position="47"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="203"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="153"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="213"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="231"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF06391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0007312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="326" mass="37165" checksum="9A978608433E1168" modified="2023-09-13" version="1" fragment="single">MSLLDDDVCPYFDTYNTCGACLSRCENCIERLFAHGPAPCPTCRQTLRKATFSEQTFEDLSVEKEVRIRKQMSSKFNKRREDFKTLKDYNDYLETVEDLTFKLVNEIDVETTKAAIDKFAAENRDLIRINADRLLNESRMATQKQEMLRLERQRRAEAYLKELEEEQAAKNEDRKNLIQELATSDKSAKTILAARQAISLKKTSMRKTEVKASSSGSSNTPSLLSDSYWRMQRDEEMDRHRDEEEDETSDTFDPVQSQYMDVDLGVGYVNSVNNNKAHAGGLVYPLLSSSIGVKDLYVEPIGVGSLSRTSKAGGYRLGFGYERAIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SW41</accession>
    <name>A0A9P6SW41_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">GRF-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_004112</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002131">
        <property type="protein sequence ID" value="KAG0007894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SW41"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006307">
        <property type="term" value="P:DNA alkylation repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14279">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.590">
        <property type="entry name" value="Alpha-ketoglutarate-dependent dioxygenase AlkB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037151">
        <property type="entry name" value="AlkB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032854">
        <property type="entry name" value="ALKBH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010666">
        <property type="entry name" value="Znf_GRF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31212">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31212:SF4">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06839">
        <property type="entry name" value="Zn_ribbon_GRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51999">
        <property type="entry name" value="ZF_GRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GRF-type" evidence="6">
        <location>
            <begin position="271"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="344"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="357"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="379"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0007894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="407" mass="45600" checksum="80793876DE857049" modified="2023-09-13" version="1">MSATPIHCHSLEPKVPKEPQTLSKLSSPGTGNGAGTAGCSEDEWDFKLATLISIFETTSEQVLQRALIDTQGDLEQAIPLILSINSSGNSSNSTGGSTPSVLSSSFSSSVYSRSSSLESLNSGKGDLPNRKKQKLIQPRFPEDVSKHCPCTLILNALDKDLATRLLKAMLIDAETWNRNRWWLFERMVESPHKTSYFAERDDDMEEVSGWTYNGMKQDKPKKFLPEMDEAKMVVRRIVNELRKSRDIGTARINITFRLRREGFSPTDTPVCKCGVAMVLRCVFKNQANYGRYFYMCYAAGSNEGRTCGAFHWVDMEEKLKLKKPAGDELEDDAMVADKECNSRSYLKRPCDSPQPEGENKSEETTGKVERHQTDVKDESELDLADELEDNDLENIPLEAIDEADLLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXE5</accession>
    <name>A0A9P6SXE5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_002279</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001558">
        <property type="protein sequence ID" value="KAG0009544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXE5"/>
    <dbReference type="OrthoDB" id="2439248at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0009544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="211" mass="23094" checksum="4206DAE6028EDA68" modified="2023-09-13" version="1" fragment="single">MNPTDLHAADNADTVISVEQVASNDEAVVPNSLEDTRQHHLQSEADNINVGEEIRPTSPPFPLGFRYPNHSLRGDYTPSIRSAHYPGHQQSMRPFSPSYRSDSHPPLGGHRFADGSQSAGRDASKLPIIDYAGLDASVTEATFIEHGFEKTTFTESTNLPESGNTKEPKKSLDRAASTASSVKRAPSSGSNVEFRRRSARKASFYSERAPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXH7</accession>
    <name>A0A9P6SXH7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Septin-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_002131</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001517">
        <property type="protein sequence ID" value="KAG0009716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXH7"/>
    <dbReference type="OrthoDB" id="416553at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032156">
        <property type="term" value="C:septin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01850">
        <property type="entry name" value="CDC_Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000328">
        <property type="entry name" value="Septin spn3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030379">
        <property type="entry name" value="G_SEPTIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016491">
        <property type="entry name" value="Septin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18884">
        <property type="entry name" value="SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00735">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006698">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51719">
        <property type="entry name" value="G_SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Septin-type G" evidence="3">
        <location>
            <begin position="13"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0009716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="295" mass="34263" checksum="B5166F4F4D5FF44C" modified="2023-09-13" version="1">MAHRIRGRKNAKKGFQFTLMVVGASGLGRTTFINTLCDADVVPKRECDEPEMAHVEESIKIKPYTVELDEDGIKISLTIVDTPGFGDMIDNEYCFQEILGYLERQYDDILSEESRIKRDRRFRDNRVHALLYFIAPTGHSLREIDIELMKRLSPRINIIPVIGKADTMTPSELVDFKKRVMEDIEHHNIPIYNFPYDPEEDDEETVEENSELRSLLPFALIGCEEEIEVNGRRIRARQYPWGVVEVDNSEHCDFAKLRFALLSSHLQDLKEITHDYLYENYRTEKLSLSSGEESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXS4</accession>
    <name>A0A9P6SXS4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001636</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001378">
        <property type="protein sequence ID" value="KAG0010263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXS4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="500"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="651"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0010263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="651" mass="75018" checksum="558B3326088274C6" modified="2023-09-13" version="1" fragment="single">MEPMRLSLASLGPWAYPAKFGNNACISSSSWAAMTTVDPSVSSPAIQYNILSLDIHPSILFRKHVHEQIPKHKALIVGTDKYDIVNDDFWCLQSTDACIRLIQLNPNLNSLAESWDDMSSFHRIRFANQLCHLETRIVQMHLSKWEVTPEMFNQLIENSPMLKVLRFSKLTVKKGMGLAVGLREDQPQQSKEPIIPTSVLNFRQLKVFAVSHASIHIRDLNVEAPDLIVLCLSFSQVNFTQPNLPQSSIWSSSSSSYAYHHPPKVFWNTPRLERLVCNRTETSVANPTLSETPHTLHTISMANYEIESRLVAQFVTAQGSHLETIRLACFSGITARDIRLILTRCPNLVNLFAPEIMMWAGDLLAIQSEDKHSEDNDLSRNECKRLEPWVCQKLERFSVYICLDASAVEDISGSHDIPYQQQAFPSRDASSSPNSVILCPMDVDKSAQQFQQHQQHQRYQQYPQYPQYQQYQQYQQYQQYQQYQQYQQYQQHQPMAWQQPMQSQALTSHQEEDQEQNQHQDHHIQDLHIHIRHALLDQLAMLTRLRHLDLSGEHVEKVDHVQIGLPWTLKDGLERLSLLQSLEHVALTGWIDEMGIPEIEWMKQSWPNLKRISVLKSNAASMSRFKSLVAEVWPELTVQDKDRSNAHCPPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SY07</accession>
    <name>A0A9P6SY07_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001913</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001454">
        <property type="protein sequence ID" value="KAG0009941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SY07"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0009941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="218" mass="24603" checksum="9B680900D336F8A4" modified="2023-09-13" version="1">MTSEVISIRDLLGERSLEDQVKDICNFYNAMTGIWTSWELNDGKTLQLTGNRLTTPHSNHDTSRRSSYGSDECPTIIKQEDPGSSRMEPIPQVPPAAAMSSKRKFDANSDAMSTLGALTFEMKKAHNLKRRKLDMVNQRLALDAKNFCEATVHVLDVKLELMDAKDHCQDELREALLETQIGKLNAKIEIMQAETNAAIAMKRTMLEIELIKAYSMRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYF0</accession>
    <name>A0A9P6SYF0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_000462</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001099">
        <property type="protein sequence ID" value="KAG0011716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYF0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="214"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="754"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="226"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="754"/>
            <end position="771"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0011716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="942" mass="109117" checksum="4CB561D6C55B52F8" modified="2023-09-13" version="1">MDSMDNQDDGISIRDEYLCTDIKTLRNLLTVNRFFFHAILPRLFGDGDPLVVWDMNYVSSKYETNRDKLFAVAFVSFMQARLDESQCDPEDDQQVDRILSGILKQYGLKMTTSFKPFLPSGLDMVEKIFWHTRNAYSKEFKEFRRNTAQRMTVDYSKLMTVLWMDEWRFFPPGSMIRLCKLPDDLRRREAISSPSDALSETHDEEPSGIVLTTIATADIPEKPEEDHSDDSDKDDDEELVLEYQHDSRYTWELRYALREMWIHYNCDCITSFVFEMAKAHKYLPLSAKMAKLQVIHIRRLDAMPDSHLENTILFIKQNLTAFPEKRQLNIEFDGTWYLLDEDEEDNITDHSLTDLNTYNAGRRNYRERCSRFMQPAIKIYEALGRPEQMQASYIPKFYDLTKHIDLDRLRSFSDEDLERIDQGERAGMEAFLRRCDDLKELNLGVGNHDVLSWAAADTRITTSPPFRRALKNLETLELRTSRSYNFVIHALSDAVDAFSTSLRKIQVKFRNDFDDQIPYPLRNAQTMESLRLQRLAPATTIGDWSVLLPNLRIFKINLKGVASINVGSFDQCPNLSILEIRFGCLDSDECRPRGSAPLSIPEHEPLSLKWRQPEIDCTLFPKWSLPNLKQLKLYDLAAMRFNLTSLTTMARLQTLIIEIDPRLCCGQDLDIRSHRLNIPMLQPTATPDSRSWRRCYLPELKEISLKGPHSALIDLDCLRSLPRLESIRLNNFGGKQEMRRHITDGFDSIFCPTDSQAEGENTDYSPQSNGARSVDNDTPFLESRLRKFKLEGDWLMSGQVATSLLTTYAPLLERLSVYGLTNGTRDGYTFLEAIHNADKINKAYEVAARSTSKDYISSRPPDMKNNQRGSLPGRNLITAKCRYSVSKEDMRSLGLREIMYGERTKYKKNGVRMYSLLDRHVIRQEDYDSLDEKTRQESDSSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZ41</accession>
    <name>A0A9P6SZ41_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_011666</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000968">
        <property type="protein sequence ID" value="KAG0012545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZ41"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="529"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="806"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="846"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1129"/>
            <end position="1166"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="661"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="935"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="68"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="123"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="173"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="185"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="234"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="258"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="313"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="390"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="571"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="809"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="850"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1130"/>
            <end position="1166"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0012545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1166" mass="129629" checksum="F09FC218612FE4AC" modified="2023-09-13" version="1" fragment="single">MNTESYLDTPQYRHPTGGTISSADYEAGEESETSSMDHQNTAGFKNNSSSSLGYPHDSVKSKQFALQHRQQTPPTQLPNSSQPLSGFATPQSSPQSQGSNHQRNDNDANSYQYSSGSDDDQDHEPASLEDLSHSTSYRVRRDSGLPPIKMTAAKRLPPFNASLSSIPAGSQIMEEEEEEEDFEDEANRHYHEEAKSLHDDEQQSMQLRDRDTDARQGNGLSRIVTKGGLKQRAVPSTSASVKSSPSPLTSVPPSTQPIRTQHTSTPQTTRPTEPDRGPADLSNPSMALAEALIAARSKAEGKPKNQQQQQSSLGSMSTNQSRSTPGHSFSYSDGGRKQAPPTTPDANGLLSNNQVRIPVPDLSPNLRGYPAHTGRQQDFDRNPEGLLYTGRTNLTLSPTSSNPDLAEYQSDSHSGSYGAARPNIGGGRISATAKYNGGNRPANPSISSSMSKYSDDYQQQRNQHQPQRYRESSLLGTSYDSANSVQQLDGEMYSRFGFAEREPDQGPHPSQSYSDNHQEDYINHRRFRTSVGSDSHPYPGNQGRGSSNSFQKLRDQSGRVEPSVPAATNGHPATSSTHSLGLSEDLHDQLTTEAEYIMNRNTELLKILSIRDDEILTLQQELEHTLKVMHEYEDDLMAMHTAAAKPYESYHQTLDQIGHEMTQQEAIVKGYQQENEKLATQLKSSVELRQEAEKRHLKIVDGLKNEMAQLRSELDNSDQERYGNADLRVLLKQSQESHERSRKNFKDKEEEYQAEISDLKERLKMTEQVLDEERRLKVEDMQKLERDIQDFRAGYDGMLARSFGSSYRGASHSKIGSSSSSADGHADTTIDMELEGDISLITDSLLKSPGKSSVGTKSTTPSPPLLDAQQQKATRPKVFDRKLASTDTLTTANAHDGTDVEQLDLEQRISKFEADNGSSRDDLRLSGLSEEHKLANKLRDRINTLNVENKRLHTELSSLSLVLRQQQAERQRRVTQLEELLDMHENTANEKLDDSNTDEGQDRIRKVIQGLLVRIRTKEAEAEFYHNAYLDKVLEMDQMALANGKHQVMANNEENQTQNVVEGLAITSASGTGTSIEAIEARRRAQAAESENSSLIREKLTLARTLEDQVDQLQSKLSAAEIAKARLQDENNALRQQGAKDQQQRRLSQNSHTNGSQDDGNNSMNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZD2</accession>
    <name>A0A9P6SZD2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA topoisomerase I</fullName>
            <ecNumber evidence="7">5.6.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">DNA topoisomerase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">TOP1</name>
        <name evidence="11" type="ORF">BGZ80_010973</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6 7">
            <text>ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.</text>
            <dbReference type="EC" id="5.6.2.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6 7">Belongs to the type IB topoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.1" evidence="7"/>
    <dbReference type="EMBL" id="JAAAID010000825">
        <property type="protein sequence ID" value="KAG0013600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZD2"/>
    <dbReference type="OrthoDB" id="47179at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003917">
        <property type="term" value="F:DNA topoisomerase type I (single strand cut, ATP-independent) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00659">
        <property type="entry name" value="Topo_IB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00660">
        <property type="entry name" value="Topoisomer_IB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.41:FF:000001">
        <property type="entry name" value="DNA topoisomerase I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.11.10:FF:000001">
        <property type="entry name" value="DNA topoisomerase I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.15.10:FF:000002">
        <property type="entry name" value="DNA topoisomerase I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.11.10">
        <property type="entry name" value="DNA Topoisomerase I, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.15.10">
        <property type="entry name" value="Topoisomerase I, Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.41">
        <property type="entry name" value="Yeast DNA topoisomerase - domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013034">
        <property type="entry name" value="DNA_topo_DNA_db_N_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013030">
        <property type="entry name" value="DNA_topo_DNA_db_N_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001631">
        <property type="entry name" value="TopoI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025834">
        <property type="entry name" value="TopoI_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014711">
        <property type="entry name" value="TopoI_cat_a-hlx-sub_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014727">
        <property type="entry name" value="TopoI_cat_a/b-sub_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013500">
        <property type="entry name" value="TopoI_cat_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008336">
        <property type="entry name" value="TopoI_DNA-bd_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036202">
        <property type="entry name" value="TopoI_DNA-bd_euk_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013499">
        <property type="entry name" value="TopoI_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018521">
        <property type="entry name" value="TopoIB_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051062">
        <property type="entry name" value="Topoisomerase_IB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10290:SF3">
        <property type="entry name" value="DNA TOPOISOMERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10290">
        <property type="entry name" value="DNA TOPOISOMERASE I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14370">
        <property type="entry name" value="Topo_C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01028">
        <property type="entry name" value="Topoisom_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02919">
        <property type="entry name" value="Topoisom_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00416">
        <property type="entry name" value="EUTPISMRASEI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00435">
        <property type="entry name" value="TOPEUc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="DNA breaking-rejoining enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56741">
        <property type="entry name" value="Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00176">
        <property type="entry name" value="TOPO_IB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52038">
        <property type="entry name" value="TOPO_IB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 6 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 6 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="DNA topoisomerase I eukaryotic-type" evidence="10">
        <location>
            <begin position="374"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="324"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="707"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="39"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="71"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="108"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="161"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="205"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="active site" description="O-(3'-phospho-DNA)-tyrosine intermediate" evidence="6">
        <location>
            <position position="809"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0013600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="850" mass="96831" checksum="7C8D0D213B261E59" modified="2023-09-13" version="1">MSDSEDMPLAARKRQQADNAPTTDDDNIDSGSDSDTPLGKRRRPAVRKKVIEDDDVVQSSDSEVPLVKRVRTAERKSYKEDSDDDGDASYKSSDSDTPLAAKKAPSAKTNGTSKSSPSTSKTNGNKGTSGKKVAPKIKEESSSDSDAPLAKKASTKKDTPSKSAAKSSKSTKVKSEPIEAKLSSKKRAKDDTDSKSKVKKVKKEEEEEEEDDDENENAWWLNNTEQDDTVKWKTLSHNGVYFPPPYVPHGVKMLYDGKPVTLAPEVEEVASFFGALLYTEHAENPTFQENFFKDFSKLAKKHKTVPEIKSFAKCDFTLMYEYFQQEKEKKKLMTKEQKQALKDEKQALEEMYGTCYLDGRKEKVGNFRMEPPGLFRGRGKHPKTGCLKLRVLPEQVTLNLSKDAPIPKAPEGHKWQKIVHDDTKTWLATWKENVNDSTKYVFLAAGSSLKGQSDFKKFETARELKKCVAGIRKAYMADLKDKKMFIRQRATAMYLIDRLALRAGNEKGEDEADTVGCCSLRFEHVTLEKPNIMHLDFLGKDSIRFQKTMEVDDQVFKNIRLFKREPAQEGDELFDRLKTSELNKHLQSLMKGLTAKVFRTYNASFTFQDQLQKLTPAKGTVAEKLLAYNRANREVAVLCNHQRAVSKGHALQMDKIVDKIRALKYQKMKLKQTILTLEPKLKKKRPEFTEPESDLEDDWIGEHEVQLMAKEREKVKAKWEKENEKRKENKEKPMTEKELKEMLKEVDAREKELAKERKSGVVPGGKGATVEKCEAQLLKLDERIAATRTAMVDKEENKQTALGTSKINYIDPRISAAWCQKYDVPLEKIFTKTLRDKFKWAMTVDADWEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T070</accession>
    <name>A0A9P6T070_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_010175</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000681">
        <property type="protein sequence ID" value="KAG0014880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T070"/>
    <dbReference type="OrthoDB" id="2448738at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0014880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="539" mass="61709" checksum="92947630FE1B1C19" modified="2023-09-13" version="1">MPAHSIFDIPHIKDGITRFLSISDLAHCVLASKEWSSLFMPVLWRTINFNGSIINTKKRLPVLECHPEFIQSLIDFDNKLLSRIDLSYQFPNLRSLDYSSTQFHSMKDCRVSDFLAASPRLEFIGLQLCISKRVDLERLINLLSSHNSLRRASFGLRCAWDPALLPQLLQVCGRFDSLKLHLEEVRGSEKAAKKELRACDEIDAALENMQPMQVRDLSIRLTMLKRRPNMLSSLLKKCTLLERLELIELRDIERLQQVLAVFQNTDFHHLKHLNLSDGTFQHGKADIAMDLIRALGTRSRDYDGGSTDCGRGLESFETYSPFAFGRKCARALVEYHSKTLVALDQSRQQSRDLQLFLDIVCSLPKLRSLRVGIWLGFGLGYFGRCISSEDSTLQSPWLCTGLATLDLDLGFPPGAQREDSSAWDDSQLDRRLVYLFEQIGRLINLREMSLKFGINLLELRRGYLSRLSGLKQLRGLDIRGSSCFHLGEMEAVWVDENWSRLVHLLLPSQILSDVNIPIENGLEDFKATMQARRPWIWIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T168</accession>
    <name>A0A9P6T168_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_009320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000546">
        <property type="protein sequence ID" value="KAG0016286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T168"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="333"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="338"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0016286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="518" mass="60281" checksum="5CE291D4E7AABE58" modified="2023-09-13" version="1">MENQGWGFEFDVEAMAKDSVTPPIRPTETIQHKDDRRVNNNSRSSDSGTSDWFRQVDPTYQDNRSSSSEDIEGFRKQGRDWDLAVEHGPDNWGRQHHWFSEATSSRFKDDVHVKEEEEDVWDIGGIEQWSVSETNLPQDQGNGNNEEEEPPLDELTKYWVTENDLDKIRLNSKRPHRPFSDTPKVNQYDGDSWGSVPEPVMSYNGEDYISDVLIEQSKRKFFTLRDGTWELLNQSTDTKITYNRRHPLPEDMAGSSRQIDSFNPNKNFQLEPYDFESEGFVGEDDWKKPKIELGAGSREDEGEEEEEEEEEEEEEPPIKTEMIESLLDMDLQEEEADEHVGNERNNFNHEQKDNFNNCSTGLLVDLTTSPPTTPEPRRDTPLELASPHDWLNQIAKKNQEHFQESQAIHKEEWSALMEKQEQDSKRLHDFIQQTSKPKTRKKTKVSTPISLTIVIETKEFGQQEIHVTGEEDLKLLVDDFCQKFKMESYEMALWVTVARAVHKQKKKLRGQQRAEGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T198</accession>
    <name>A0A9P6T198_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">V-type proton ATPase proteolipid subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">VMA3_2</name>
        <name evidence="13" type="ORF">BGZ80_008200</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.</text>
    </comment>
    <comment type="function">
        <text evidence="9">Proton-conducting pore forming subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10 11">V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1). The decameric c-ring forms the proton-conducting pore, and is composed of eight proteolipid subunits c, one subunit c' and one subunit c''.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Vacuole membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the V-ATPase proteolipid subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000438">
        <property type="protein sequence ID" value="KAG0017515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T198"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033179">
        <property type="term" value="C:proton-transporting V-type ATPase, V0 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18175">
        <property type="entry name" value="ATP-synt_Vo_c_ATP6C_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18176">
        <property type="entry name" value="ATP-synt_Vo_c_ATP6C_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.610:FF:000001">
        <property type="entry name" value="V-type proton ATPase proteolipid subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.610">
        <property type="entry name" value="lithium bound rotor ring of v- atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002379">
        <property type="entry name" value="ATPase_proteolipid_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000245">
        <property type="entry name" value="ATPase_proteolipid_csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011555">
        <property type="entry name" value="ATPase_proteolipid_su_C_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035921">
        <property type="entry name" value="F/V-ATP_Csub_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01100">
        <property type="entry name" value="V_ATP_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10263">
        <property type="entry name" value="V-TYPE PROTON ATPASE PROTEOLIPID SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00137">
        <property type="entry name" value="ATP-synt_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00122">
        <property type="entry name" value="VACATPASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81333">
        <property type="entry name" value="F1F0 ATP synthase subunit C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7 11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <keyword evidence="11" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="64"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="94"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="134"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="V-ATPase proteolipid subunit C-like" evidence="12">
        <location>
            <begin position="25"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="V-ATPase proteolipid subunit C-like" evidence="12">
        <location>
            <begin position="101"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00045519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00046480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0017515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="169" mass="17170" checksum="6B923F50AB5B016B" modified="2023-09-13" version="1">MCPIPLPLLQIAVFSPVYSPFFGVMGATSAIVFCCFGAAYGTAKSGVGLTSMGVLRPDLIMKGVVPIIMAGIIGIYGLVVSVLIGNGFSQTMSLYAGFIQLGAGLSVGLAGMAAGFAVGIVGDAGVRASAQQPRLFTGMILVLIFAEVLALYGLIVALILNTKASDSKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1A1</accession>
    <name>A0A9P6T1A1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein-S-isoprenylcysteine O-methyltransferase</fullName>
            <ecNumber evidence="5">2.1.1.100</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_007855</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>[protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine + S-adenosyl-L-methionine = [protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine methyl ester + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:21672"/>
            <dbReference type="Rhea" id="RHEA-COMP:12125"/>
            <dbReference type="Rhea" id="RHEA-COMP:12126"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90510"/>
            <dbReference type="ChEBI" id="CHEBI:90511"/>
            <dbReference type="EC" id="2.1.1.100"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Endoplasmic reticulum membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.100" evidence="5"/>
    <dbReference type="EMBL" id="JAAAID010000410">
        <property type="protein sequence ID" value="KAG0017845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1A1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004671">
        <property type="term" value="F:protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007269">
        <property type="entry name" value="ICMT_MeTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12714">
        <property type="entry name" value="PROTEIN-S ISOPRENYLCYSTEINE O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12714:SF9">
        <property type="entry name" value="PROTEIN-S-ISOPRENYLCYSTEINE O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04140">
        <property type="entry name" value="ICMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="148"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="175"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="222"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="255"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0017845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="311" mass="35155" checksum="DC11CBF4CE3AA5C4" modified="2023-09-13" version="1">MDELALVLVDLEKDDARCDEESNLISKNVDLIAHVIDHPKNAPVNTNPIQISNSNRQALVIRVSIARTDNAKSQPRRYGLIQPMRASADSSKDTADIMYAKAACITAHTLAVIFSIRHPRSSSTKEKADKVKDEGLFSKVMIDFLPRFGQSAAAAVAGLYIFLMSRGIIPEQLKTWQIATTAVGMFGFFLRMWSFRTLDRFFTFSLTIRPNHRLVQDGPYRLLLHPSYTALMLVGTTYLFSLANEGFWTKIIKPYMLIPVPGSVLVAIGIMTAISLAMYRVRGEEKMLEQHFGSEWKQHASQRWRFIPYVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1E0</accession>
    <name>A0A9P6T1E0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Aminopeptidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BGZ80_008199</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000438">
        <property type="protein sequence ID" value="KAG0017514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1E0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042277">
        <property type="term" value="F:peptide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043171">
        <property type="term" value="P:peptide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09601">
        <property type="entry name" value="M1_APN-Q_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.390.10:FF:000001">
        <property type="entry name" value="Aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.50.20:FF:000002">
        <property type="entry name" value="Aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="entry name" value="tricorn interacting facor f3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045357">
        <property type="entry name" value="Aminopeptidase_N-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024571">
        <property type="entry name" value="ERAP1-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034016">
        <property type="entry name" value="M1_APN-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001930">
        <property type="entry name" value="Peptidase_M1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050344">
        <property type="entry name" value="Peptidase_M1_aminopeptidases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533">
        <property type="entry name" value="PROTEASE M1 ZINC METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533:SF174">
        <property type="entry name" value="PUROMYCIN-SENSITIVE AMINOPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11838">
        <property type="entry name" value="ERAP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17900">
        <property type="entry name" value="Peptidase_M1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00756">
        <property type="entry name" value="ALADIPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="Leukotriene A4 hydrolase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Aminopeptidase N-like N-terminal" evidence="14">
        <location>
            <begin position="8"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M1 membrane alanine aminopeptidase" evidence="12">
        <location>
            <begin position="220"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="ERAP1-like C-terminal" evidence="13">
        <location>
            <begin position="509"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="903"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="978"/>
            <end position="1003"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="903"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="978"/>
            <end position="987"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="988"/>
            <end position="1003"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="292"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="291"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="295"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="314"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="10">
        <location>
            <position position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF11838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF17900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0017514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="17">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1041" mass="118672" checksum="4EA767F9AB09AF71" modified="2023-09-13" version="1">MYRVIICIAEPTFGITLNAKELNIQTATARDHLNGHSVIATSVSYNVEEETITLEFPQVLHVGSSWILDVTYIGLVNDKLNGFYRSVYTDADGNVHQLTTTQFQSTHARRAFPCWDEPAIKATFSLTLVAPQGMACLSNMSEQSRTLLENGMQEVTFLKTPIMSTYVRFDKYMKYLQKDIYAWVIGDFDYIEAYTSGEFNGERIRCRVYTPVGLADQGRYSLDLAVKSVEYFSRLFNIPYPLPKLDLVAVPDFAPGAMENWGLVAFRTYALLIEEYGSQDRRNEIAITVIHEMSHQWFGNLVTMEWWSDLWLFEGFATHLAYIVVDELFPGWNIWTDFYKQIQEVLKHDSLRTSHPVEVGVANPCEITQIFDEISYMKGASVLRMLSAWLGQDQLLLGIRKFIHKYMWSNANTEDLWATLAEECKVDVPGFMSKWTRQTGYPVLSVTELDESTILVRQNLFLSTGDVRDDEDTLIWPVPLGLVTASDPTPRNIMLDTKEMILKVDTTRWYKFNMEQTGFFRVSYPSKTLDLLGQTFGTAQLSAVNRVGLLTDVAALVTSGIAPTSSFLTLLKYFEDEQDYMVWAEVSIRLQELLAVWLEQPEPIMNGLKEVQRRLFTKIVKRLGWEFPEGEDPSTGNLRAVAIRFAGRAGDPDIVAEARRRFRSFMKDRDMTAISPDLRFPVFEIVLRSTQGVEEYEDIVNYYRETFVPAEKMVALSVLGYGNSQELVRRTLALAMSPEVRTSDILSAIATLRSSVIGRAELWNFMRHHWDVLYERHFGDIGFLDYFVSLSIESFSTLERYHEVQAFFANKDTSAYDRILATCLEGIRMNILWLGRDCKDVEEWLRVNGYLIDEATADNHVGEITNGTQGGTTEAHGGIAKGLLGINVNPLVLPSSSINGGSSITGTSSGASSGASTPPGGLQYPQGSIYSQHGAHVRSQVYLDGVGQASEEQTLQLLQLQQDQQQHELRMQREYQLQLQQQQQQQHQHQHQHQHQHQHQHSLNHNHNHINHTQLSRHQEQRPRTLEREMELLSMSGDYEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T255</accession>
    <name>A0A9P6T255_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Karyogamy protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006332</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000312">
        <property type="protein sequence ID" value="KAG0019075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T255"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="221"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="453"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="547"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="667"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="769"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="840"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1013"/>
            <end position="1050"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="222"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="474"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="561"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="674"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="770"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="840"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1013"/>
            <end position="1030"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1031"/>
            <end position="1049"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0019075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1089" mass="119430" checksum="959D97AA2B178BE4" modified="2023-09-13" version="1">MAAVSLRLDGLSEVTELESIPLPYKTLYHTLVFKNEMPIDLLRERRQTGSEQLMTWIKAALKLLESVSESQQYQQRQQLDEDEDEELEAEIQDVVSGFGQYEPTIESSIQILVELEKAIAHRSSSSSSLSSSAYDVDEGFNESRDCLTPEMEILQERWSHLRGIIGDLTGSVREHQRLRDGIQSVRNTSELAQQAIGILEKCLKDIASDRKRTAEIALAEASSRNNSTSSLGSNDSTASLRARAQSSGVDSNDMLELDSRIGLLMVQIDALQKTYPECTRSHRSHRKSRSIKQQETGSIAEKKQLIYKLFKELCKSWHSLRTRRDQLWRDLEECDRWRTRIEKMAKQIETMLEPVEVFHRMCLNLLTTLNGQVSTEELSAHGSQLSLTIANLDITDAGAPRILRGSNGDMTDEPVDLELLSSTLQELDEKQNTVAPAIENMFWVQEGEIQHRTKTAPTTPTTAHSQAPHSHQFPPESTTSVTPPSSDTSPMYPSLDMLERQRNLKSRWSNLKTSLDTVGTKLHAHHAYLKEKANLALKKEEPAEDKTLIGSGNSVDGGDWTSATRPTSPTLRRSMTSISQKSTLSTIPPNWSESSNRFLRGKLVSSISTDSPAVKKFMLVKSDAPALDRPRPWCPSVSTSSPSMPGFPLQTSTWGYFILSPGGENGEQIIATPAPLPVRPPTPPKPEPPKINRPPFSPGGNRRYTSLSKPPPSRSALPSRSASVAGYNHVNKSNASVYMTASGDAMEWTQTLRRSTSSSTVKPMVFASRSHNANASTTSFASSKPRRSFTTDPRTIDRRQSISVGSRRRSESISSNYTIQSWKGHELAATGYQGQQYNYNNGDNYTSGNNYNNGNNYTNVNNYNNGNNYTNVNNYNNSNSNGNGSGNSNGNSNNNKANNGRMSSLSSISDTSEDGTIMGTTRHNEHVGVRAMFTKNSSTSSVDSMLSDVSSSLSSVIAGIGNTFGPSMASSLGGSSSNARSPSPYNNMFGSSFAAARSSAALHSAYMASMSSSSSASLKHRSNSSLSGCESRSRSRQEQGRDRSREHISKIVGGMTPIPSASSWMSSMNTGSILSALSFTVPTYNGADT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T286</accession>
    <name>A0A9P6T286_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_005644</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000278">
        <property type="protein sequence ID" value="KAG0019543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T286"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0019543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="631" mass="71789" checksum="99600F58A1080D4F" modified="2023-09-13" version="1">MSVPPTRSPALAVFSIPELAAHIGLYLRPTQRQRLCLVSKTLYVAFPPSLHISMSSSFLPLSKPPLNSTEIQALVSRIRGLSLNIHDDQTSQIQIDLLNNVYKHCATLETLNIEYQGKDVAVLKDVLVILPRIRNLSLTFMDNITTKIAVQTLVGTRNMISDGNESGCLQSLEIDFGAQGDRYLAWSHLKQLLRSYPDLKSLSLSGVSFWKRTRGPPTSDDDDDNDNDYEEILEHDKSSQWPRRLRQYPKMERLKFNRCTLAEDRLIDMDKLFPWLQTLEIIGCGGTWQTVLERPLPTPWRHPSAATTPLNSLPQTKYSFSELRRLVIWLEFQSGRSELVNLVRGRPYLSTLETDLLPLRRGGLLALAEYSSDHLSAESTTKVATAELEKDGDAAPAQNRFKRLGIQTYSSPPLTTEVLDQFYGSACFKELDYVFMQCRILTMKRFPFAKTLRSLYLGGVEECLSHDEEATLRNILLQLPVLEVLRIDRYIDSYKLFSGLGREPSSTLPDSDQADLTAGSGINNIQDWTWMNESPFLYDLEFYVRLPPELAGDTSEPTSLAKSDGHTMSLENLQRQVLDRFRFLERLKLHMKAGNRRFELPAADELVAWKKKVQEERGEGSRLPLVEFAMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2R7</accession>
    <name>A0A9P6T2R7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC transporter ATP-binding protein arb1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ARB1</name>
        <name evidence="7" type="ORF">BGZ80_003765</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000201">
        <property type="protein sequence ID" value="KAG0020705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2R7"/>
    <dbReference type="OrthoDB" id="2110130at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03221">
        <property type="entry name" value="ABCF_EF-3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000549">
        <property type="entry name" value="ABC transporter ATP-binding protein arb1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000618">
        <property type="entry name" value="ATP-binding cassette (ABC) transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032781">
        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050611">
        <property type="entry name" value="ABCF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211:SF15">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY F MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211">
        <property type="entry name" value="ATP-BINDING TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="86"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="399"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="156"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0020705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="619" mass="68658" checksum="8877451F79BEB9D0" modified="2023-09-13" version="1">MSALSASKQKRLAAKAAKEAAKKSSSASSPATTNGRNTPALSEGAPEADDADALIPGLNAMDVAKQKSNDRNSTGVLTSQPLSRDIKIESFSLSFHGRELISNTDIDFNFGRRYGLIGANGSGKSTFLECLAAREVPIPEHIDIYLLQEEAAPSDHNAIEAVVIEAKHEVERLEKQVEDMLAEVDGAENPLLDDVYDRIEQLDPSTFETRAATLLHGLGFSKKDMLKATKDMSGGWRMRVALAKALFVKPTLLLLDEPTNHLDLEACVWLEDYLSKYDRILVLISHSQDFLNGVCTNIMNLNHKRKLVYYGGNYDTYVKTRAELEVNQMKAYYKQQDEIAHIKKFIASAGTYSNLVRQAKSKQKIIDKMEAAGLVEKVDPPALFKFKFSDTDKLPPPVLAFDEVGFAYSGNMKDALYRGVNLGIDMDSRVALVGPNGAGKSTLLKLMTGELTATEGRIQRHMQLKLGKYNQHSADQLDMELSPIDYLRKRFPDMPQDIDHWRQQIGRYGLTGSHQTSPIGHLSHGLQTRLVFAELALSRPHMLLLDEPTNHLDMESIDSLADAIKNFSGGVVLVSHDFRLLKEVADQIIVVDKGVSVFDGTILEYKKILQKKSRESNLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2X7</accession>
    <name>A0A9P6T2X7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PIN2/TERF1-interacting telomerase inhibitor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PINX1</name>
        <name evidence="3" type="ORF">BGZ80_003768</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000201">
        <property type="protein sequence ID" value="KAG0020708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2X7"/>
    <dbReference type="OrthoDB" id="29523at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010521">
        <property type="term" value="F:telomerase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050656">
        <property type="entry name" value="PINX1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23149">
        <property type="entry name" value="G PATCH DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23149:SF27">
        <property type="entry name" value="PIN2_TERF1-INTERACTING TELOMERASE INHIBITOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01585">
        <property type="entry name" value="G-patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00443">
        <property type="entry name" value="G_patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G-patch" evidence="2">
        <location>
            <begin position="26"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="240"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="302"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="311"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="329"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="349"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0020708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="382" mass="42316" checksum="7D3B8B0C74A2301E" modified="2023-09-13" version="1">MSLKAVRHPKQRLAPDPRNLHWANDTNKFGFKMMEKMGWSQGKGLGAKEDGAQEHVKVRLKDNNLGVGATKKSIDNWLGNTDAFSKLLEDLNERVAKESQEKASESSSESESEKSDSKEDEKKSSKKSKKEAKEKKSKKEKKEKKEKKEKKSKKSEKSSEEDSDDKSSEDKTCIAAAISGRKASRHKYLKNKHAAIQNAERLNEILGIKSETASPITSGMSTPVAQEPMTSTDIFAARMQQNSAKTSSGDDEEPARPMFGGLGFATSAGIGSSGFNKTGLRGLGFVKATVSVMPATIETKVEEQIVEESTSEAASTTSETLVKEDKKSKKEKKDKKEKKDKKEKKEKKGKKDKEDKENSSIKKDKKRKAEDTDRSSSKKSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T312</accession>
    <name>A0A9P6T312_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_004603</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000233">
        <property type="protein sequence ID" value="KAG0020203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T312"/>
    <dbReference type="OrthoDB" id="10693578at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0020203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="154" mass="16711" checksum="9D34C01ADCEB2725" modified="2023-09-13" version="1">MTEGGDGGGHGLSLAVGSESGDVSYWKLVEIESLDLDTSHSDRTIPSRHDVYHGNKHENNSDKVGERVCEKTYKLLMQWTTAYGKLNAEGAIIEGTKGLGRSNLRLLKQHGACGEAAAPLDFHQAVTQVMRSKNVLSKFGARQTTENVNQVNEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3G0</accession>
    <name>A0A9P6T3G0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">TatD DNase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">TATDN1_1</name>
        <name evidence="6" type="ORF">BGZ80_001242</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000128">
        <property type="protein sequence ID" value="KAG0022013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3G0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008296">
        <property type="term" value="F:3'-5'-DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01310">
        <property type="entry name" value="TatD_DNAse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018228">
        <property type="entry name" value="DNase_TatD-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001130">
        <property type="entry name" value="TatD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050891">
        <property type="entry name" value="TatD-type_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10060:SF15">
        <property type="entry name" value="DEOXYRIBONUCLEASE TATDN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10060">
        <property type="entry name" value="TATD FAMILY DEOXYRIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01026">
        <property type="entry name" value="TatD_DNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005902">
        <property type="entry name" value="DNase_TatD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01091">
        <property type="entry name" value="TATD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR005902-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0022013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="256" mass="28839" checksum="26C0EA0A42C4D0B3" modified="2023-09-13" version="1">MPPRLIGDLAQVLSRAKQAGVNRMIVTAGNLSDCKEALDLTRGHDGLFMTVGCHPTRCSEFESHGDGPEGYFRELKAMLENPEARQKIVAIGECGLDYDRLQFCPKETQLKYFERQFELAESTGLPMFLHNRNTGSDFGKLISEHRSRFTNGVVHSFTGTLEEMQHYLDLGLYIGINGCSLKTEENLSVASRIPLDKLMLETDGPWCDIRPTHASYRYLSKMTAEQHAIYNPPAKKKERFELGSMVKSRNEPCTMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3H5</accession>
    <name>A0A9P6T3H5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Eukaryotic translation initiation factor 3 subunit B</fullName>
            <shortName evidence="8">eIF3b</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Eukaryotic translation initiation factor 3 90 kDa subunit homolog</fullName>
            <shortName evidence="8">eIF3 p90</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Translation initiation factor eIF3, p90 subunit homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 12" type="primary">PRT1</name>
        <name evidence="12" type="ORF">BGZ80_000176</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.</text>
    </comment>
    <comment type="function">
        <text evidence="8">RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8 9">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the eIF-3 subunit B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000103">
        <property type="protein sequence ID" value="KAG0022474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3H5"/>
    <dbReference type="OrthoDB" id="10250414at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005852">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031369">
        <property type="term" value="F:translation initiation factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12278">
        <property type="entry name" value="RRM_eIF3B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000419">
        <property type="entry name" value="Eukaryotic translation initiation factor 3 subunit B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000235">
        <property type="entry name" value="Eukaryotic translation initiation factor 3 subunit B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03001">
        <property type="entry name" value="eIF3b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011400">
        <property type="entry name" value="EIF3B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034363">
        <property type="entry name" value="eIF3B_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013979">
        <property type="entry name" value="TIF_beta_prop-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14068">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 EIF3 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14068:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08662">
        <property type="entry name" value="eIF2A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036424">
        <property type="entry name" value="eIF3b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 9" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="7 8 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 8 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="RRM" evidence="11">
        <location>
            <begin position="35"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="700"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="711"/>
            <end position="720"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR036424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0022474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="735" mass="84478" checksum="9F8FDA2B02EA6E12" modified="2023-09-13" version="1">MARFDLNNLPEREEDIDFSDIEERYQLSFEEGFDNVVVVDNIPLVDETKEEKLIQFLRKIFKNVGEIRDNHFVMPKAVNEKGKLMSKGFMFIEFETAEQASLAVKLIDGFKMDKSHTLAVNRFTDVEKYSAVEEEFHAPPEEEFVEKEHLKSWLADELGRDQMVIYRHNDVQVLWNMQKEQPQVAHSKTNWTETYVQWSPLGSYLTTFHAPGVALWGGESWKKIIRFSHPGVKLVDYSPNERFLVTWSNEPIVVPEENYDGPFGPEDEGNQIVVWDVKSGALLRSFPSINTQSSNARSTVSWPVFKWSPSERYFARVTPGSQISIYEAPGMGLLNKKSVKIDGVVDFEWAPSSTADKSGKIKDDMLAYWTPEVDNQPARVTLLNVPSLDIVRTKNLFNVNDCKLHWQNQGDFLCVKVDRHTKNKKITYSNLEIFRVREKDIPVEVVEVKDQILAFAWEPKGERFAIITSNDPNLTAATPGSTTLKTSASFYYLDKGKGKDTLQSFKVIKTLTGKSCNTIFWSPKGRNVVLATLRSQTVWDLEFYDLDFEPLESAASKVPTGGEKDPAAYLQLLTSGEHYGVTDIEWDPSGRFVATSASMWRHTMENGYQIWDFKGQLLYKENLEKFKQLVWRPRPKTLLSKDQIKAIRKNLREYSAKFDEQDMESSSQVSTAERQRRRQLLEDWANWRKRVEADLALERAASGQQVSTATAEDEEAEEVDEWIEEVIDEKEEIVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3S5</accession>
    <name>A0A9P6T3S5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">26S proteasome regulatory subunit 4 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">RPT2</name>
        <name evidence="13" type="ORF">BGZ80_010515</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000074">
        <property type="protein sequence ID" value="KAG0023054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3S5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008540">
        <property type="term" value="C:proteasome regulatory particle, base subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19502">
        <property type="entry name" value="RecA-like_PAN_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000067">
        <property type="entry name" value="26S protease regulatory subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000007">
        <property type="entry name" value="26S proteasome regulatory subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000039">
        <property type="entry name" value="26S proteasome regulatory subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050221">
        <property type="entry name" value="26S_Proteasome_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032501">
        <property type="entry name" value="Prot_ATP_ID_OB_2nd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23073">
        <property type="entry name" value="26S PROTEASOME REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16450">
        <property type="entry name" value="Prot_ATP_ID_OB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7 13" id="KW-0647">Proteasome</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="12">
        <location>
            <begin position="227"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="94"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="24"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="94"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00068880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0023054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="449" mass="50488" checksum="C0DBCE69921B8DF1" modified="2023-09-13" version="1">MRSSLDLRLLGNQQSQPPNANKGQKKDEKEPKKKWEPPLPTRVGKKKIRKGPDASSKLPAVFPTTRCRLKMLKMERIKDYLLMEEEFVVNQERLKPQEEKTQEERSKVDDLRGTPMSVGTLEEIIDDDHAIISTSNGPEYYVSILSFVDKDLLEPGCSILLHHKTMSVIGVLQDDADPMVSVMKLEKAPTESYADIGGLETQIQEIKEAVELPLTHPELYEDMGVKPPKGVILYGVPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEENAPSIVFIDEIDAIGTKRYDSNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNQIESLDPALIRPGRIDRKIEFPMPDVKTKRRIFNIHTGRMQLADDVDLEEFVMSKDELSGADIKAVCTEAGLLALRERRMKVKADDFKKAKEKVLYRKNEGTPEGLYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T423</accession>
    <name>A0A9P6T423_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tetratricopeptide repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_009519</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000058">
        <property type="protein sequence ID" value="KAG0023395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T423"/>
    <dbReference type="OrthoDB" id="5587616at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="15"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="54"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0023395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="102" mass="11559" checksum="6AAC2777CA77E009" modified="2023-09-13" version="1">MVEKYLSPEERAMVAANSVQDGDKYLNEGGFDEAIKCYKKALECHPDKARNRIGDAYILKGNVYRDRGNFGDADKYYKRALEYSQDEAMNPPRGNTSEKVLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T459</accession>
    <name>A0A9P6T459_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">biotin synthase</fullName>
            <ecNumber evidence="4">2.8.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">BIO2_2</name>
        <name evidence="15" type="ORF">BGZ80_009201</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; biotin biosynthesis; biotin from 7,8-diaminononanoate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the radical SAM superfamily. Biotin synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.6" evidence="4"/>
    <dbReference type="EMBL" id="JAAAID010000053">
        <property type="protein sequence ID" value="KAG0023519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T459"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004076">
        <property type="term" value="F:biotin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009102">
        <property type="term" value="P:biotin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01335">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000011">
        <property type="entry name" value="Biotin synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01694">
        <property type="entry name" value="BioB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010722">
        <property type="entry name" value="BATS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002684">
        <property type="entry name" value="Biotin_synth/BioAB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024177">
        <property type="entry name" value="Biotin_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaA/NifB-like_rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00433">
        <property type="entry name" value="bioB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22976">
        <property type="entry name" value="BIOTIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22976:SF2">
        <property type="entry name" value="BIOTIN SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06968">
        <property type="entry name" value="BATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01060">
        <property type="entry name" value="BATS_domain_containing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00272">
        <property type="entry name" value="biotin_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01278">
        <property type="entry name" value="biotin_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00876">
        <property type="entry name" value="BATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="10" id="KW-0093">Biotin biosynthesis</keyword>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Radical SAM core" evidence="14">
        <location>
            <begin position="104"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0023519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="409" mass="45084" checksum="F5E773AFB6B4D75A" modified="2023-09-13" version="1">MSFTSLRLLSSRAIQISHTKNAAFQLSRAYTVASSPTKFATIDESARAQKQMAFGRELSAAALNAHGELRFDWKKEEIEAIYHSPIMELLYHGANVHRMHFDPLAVQQCTLLSIKTGGCSEDCKYCPQSSSYSTVVKAQKMLDTDEVLNAARAAKAAGSTRFCMGAAWRDLAGRKSNFKKIVGFVKEIRAMDMEVCCTLGMLNDDQANQLKEAGLTAYNHNLDTSREYYPKIITTRSYDERLETISKVREAGISVCSGGIIGLGETDTDRVGMLHTLSTMPAHPESVPVNALLAVEGTPLEKQEPVKVWDMIRMIATARIVMPKTMIRLSAGRVRFTEAEQALCFMSGANSIFTGDKLLTTPNNRFNADQQMFETLGLVPKAASFKVDLSAESEVNEKKECCGGNHDHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MCS1</accession>
    <name>A0A9P6MCS1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">mitochondrial processing peptidase</fullName>
            <ecNumber evidence="4">3.4.24.64</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Beta-MPP</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BGZ80_008706</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalytic subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins. Preferentially, cleaves after an arginine at position P2.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of N-terminal transit peptides from precursor proteins imported into the mitochondrion, typically with Arg in position P2.</text>
            <dbReference type="EC" id="3.4.24.64"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.64" evidence="4"/>
    <dbReference type="EMBL" id="JAAAID010004814">
        <property type="protein sequence ID" value="KAF9992114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MCS1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006627">
        <property type="term" value="P:protein processing involved in protein targeting to mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.830.10">
        <property type="entry name" value="Metalloenzyme, LuxS/M16 peptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050361">
        <property type="entry name" value="MPP/UQCRC_Complex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11851:SF149">
        <property type="entry name" value="GH01077P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11851">
        <property type="entry name" value="METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="LuxS/MPP-like metallohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M16 C-terminal" evidence="13">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00045757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9992114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="140" mass="15866" checksum="B92C6850A7884B83" modified="2023-09-13" version="1">MSFNTSYTDTGLFGIYFITENKDCQDDLIHFAQKEWARLTTSVTSAEVERAKQQLKSSLLLSLDGTTAIAEDIGRQLVTTGKRTSPQEVEQLINKITAADVHRVASQYLWDREIAMVGIGPIECMPDYGRVRNNMSWNRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MDU3</accession>
    <name>A0A9P6MDU3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007999</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004209">
        <property type="protein sequence ID" value="KAF9993883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MDU3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9993883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="369" mass="41431" checksum="DED2E22321185C86" modified="2023-09-13" version="1" fragment="single">MHTQRAMSASNLHQVDQHGKLSEEDFEKACLDVASSLRLRIADMKIAEQEKTGNDVDPDLMDIASFSLGHPSTNTEQEDDEIEDRASRGTETEDEEDESSPSDNVGPGDDDIGDGAAGEASTVEGAESIEKRKALLEARLRGGVRDAIRDSLMYDPYISETAEAFGIPEDERITVDKDNRLTFYLKANYFEDWKERHQVNIGTSFSPHGNPHTYSVKVHKDSAQSKKERAGQTVTYYDCHCRGKKSEQKLSPGGKSGKTRMRTPSIRCGCSSRFSAIYQPTPTSDGMPGNSYRIEYNYQHNHVLGDKSAIGTQRKSKAVRERIRAMILRGMTIQVIMDQLTIDHARFTRIMTSDDNQRLSRDDFITYDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MFD2</accession>
    <name>A0A9P6MFD2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_007324</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003725">
        <property type="protein sequence ID" value="KAF9996177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MFD2"/>
    <dbReference type="OrthoDB" id="294295at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052178">
        <property type="entry name" value="Sec_Metab_Biosynth_SDR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43618">
        <property type="entry name" value="7-ALPHA-HYDROXYSTEROID DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43618:SF17">
        <property type="entry name" value="RHAMNOLIPIDS BIOSYNTHESIS 3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9996177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="262" mass="27639" checksum="97049229F9F4B4E5" modified="2023-09-13" version="1">MQSSSLFDVKDKVVLVTGGGRGIGLMIAHGFVVNGAKVYISSRSAKVCDQVAEELNKLGQGQCISIPADLQSLDEVKRLVAEISKRESKLHVLINNAGANWGEAIATYPDQAFEKVMNLNLKRVFSLTQAMIPLLEAAATAATPSSIINIGSIDGIRVPPQETYAYSASKAALHQMTRVLAGHLGARHITCNAIAPGPFESKMMAETLRKMGDQIIAGLPLGRIGQPEDIAATSIYLASRAGAYTTGAIIPVDGGSLVRAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MG01</accession>
    <name>A0A9P6MG01_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_007011</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003518">
        <property type="protein sequence ID" value="KAF9997410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MG01"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.50">
        <property type="entry name" value="R3H-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052145">
        <property type="entry name" value="Mediator/Homeobox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001374">
        <property type="entry name" value="R3H_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036867">
        <property type="entry name" value="R3H_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24330">
        <property type="entry name" value="HOMEOBOX PROTEIN BARH-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24330:SF19">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01424">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00393">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82708">
        <property type="entry name" value="R3H domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51061">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="143"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="R3H" evidence="4">
        <location>
            <begin position="318"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="22"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="279"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="394"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="28"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="52"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="410"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9997410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="497" mass="56688" checksum="8F038404A882113E" modified="2023-09-13" version="1" fragment="single">MTTNDLSFDAMSLRDNGIASPIDRRYSQYGSARAQTNPVTRKPTTGSQRNSVRADGRDVRRQSNRLSLANVDWNPSQASPVQSPMLQQDPRQLQQHMNTFGYQQAPLMQQTSYMTQQQQQQQQQQQQQQQQQVVEDQADTIPTAIVIKNIPFSVKRDALLAILDNLDIPKPYAFNYHFDNGIFRGLAFANYRTAEETEIVVNAVNGLDVSGRKLRVEFKKVMPAAEQEKREQEKAAALAAEIQHRRELEMMEAQILEQERREQERRELELQNREFERDRRNRSSVMLERQSSVRSAERDDSDSRYSLSASSSQLDLNDGETLAFYDRLLMFRGDPTKDDMIFPENLNARQRRILHLIADKLSLHHFSEGEGNLRRLIITKTPPPNVALETAVNRSPKQRPMSFAGRGSLRSESPVTKTKTPIADTPPVSASPTRSLYRKSMILNPESAGNVIYPIRQPKGPEPGKVFTVREQKQLRDATMIAPGFEVHPQPTRTFSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MH97</accession>
    <name>A0A9P6MH97_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_006346</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003129">
        <property type="protein sequence ID" value="KAG0000528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MH97"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0000528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="149" mass="16511" checksum="E19AC187986BB6A7" modified="2023-09-13" version="1">MKQAGWTIHVCQTETDVAIAVDCQPDDVVISQDSDMLAYKSVSTIWRPISGYLVLEYKLTDVCQQHSLTRDHLTAIAVVSSNDYTATIVAAYLTHITVLTKNTTGEALDASLKVFVEMKQTVIDPKDTPVASLSFNDLSQRLNDLRSLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MI01</accession>
    <name>A0A9P6MI01_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GATA-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_006275</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003095">
        <property type="protein sequence ID" value="KAG0000862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MI01"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00202">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GATA-type" evidence="3">
        <location>
            <begin position="114"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="164"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="424"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="165"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="196"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="219"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="247"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="272"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="289"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="434"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="446"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0000862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="629" mass="68544" checksum="8192ACEAB19BAD60" modified="2023-09-13" version="1">MMLQSQFQQQHHYSRQQHHQLHSTMNDEDPFGEYVVMDMSHGQMMAEGFRPMDDSNLALGMNNEITSSPDVNNVGMPQFNANNPSVPNQAWSLAAALQKPSAKSTKTKKASTRPPRALECFNCKVTQTPLWRRTLDRKHSLCNACGLYYKQYNGHRPLHIRHKPSLSQSQQRENASPYTLSPPNGGAALNQKKESSSSPGSTSPVMSPNESFKGDEPESASTTPANEAMTESANEKSAEGSMPLEQEASQPEQDAESQSQDANGDSSADGATKSSSVTFKTEGTRVKRSSSNGNSKSQKMLSRHRQTRSFTGPIHTDTYAGVPATMAHSAEWRTYAPMGEVSNAMMLGQIPTPVQDAAYGNYPAGLLSEDLNGVSDSPLLMCDGGPFSPTSTLCSPLTASTVPSMAHGPMAPYSLPPTAIGGTSPAPADGMTKTTSAAAGAGTASEDNQSGNQKSPIFDDMRFHVLVDNMRPGQMFRFLNILESRCHVLRHRLGMPPSPTTPGPLSPQQQQQHMNVLMAQQQQQQQQSMVNTPTTECGFQSLSLSSPPAKDEHLSYPWHSMNTTATTFQQQGQQAMPYLYSNEAHIQRDNSADGEDVKEEDDCAQRQFQQHFWQPNATTASMAIYATSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MIX4</accession>
    <name>A0A9P6MIX4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005817</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002865">
        <property type="protein sequence ID" value="KAG0003287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MIX4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040441384" evidence="1">
        <location>
            <begin position="19"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0003287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="76" mass="7938" checksum="6AF0ED821760B966" modified="2023-09-13" version="1" fragment="single">MQFKTLALAAVAAVAVSAQTFDNNPCTQCVYSSFSKDSVCATLNATQLTEITSAFENNTVNAIQIATASKDSAIKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MLT9</accession>
    <name>A0A9P6MLT9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Succinate dehydrogenase assembly factor 4, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">FMP21</name>
        <name evidence="4" type="ORF">BGZ80_004660</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SDHAF4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002354">
        <property type="protein sequence ID" value="KAG0007434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MLT9"/>
    <dbReference type="OrthoDB" id="201362at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034553">
        <property type="term" value="P:mitochondrial respiratory chain complex II assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012875">
        <property type="entry name" value="SDHF4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28524">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 4, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28524:SF3">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 4, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07896">
        <property type="entry name" value="DUF1674"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="73"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0007434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="127" mass="13572" checksum="ACEEB9ED33F194D8" modified="2023-09-13" version="1">MSSSFATFALRSSANPVLLRTPRTSTLSSPATGALTALVLQRSYSSTGIRPRAPAPIPLGSAKDQAEFEQLVKEAESAPLTSHPDARTPVPEEFEGDTNPITGEVGGPKREPVRFGDWSFKGRVTDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MLZ7</accession>
    <name>A0A9P6MLZ7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_004547</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002305">
        <property type="protein sequence ID" value="KAG0007543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MLZ7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="3">
        <location>
            <begin position="59"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="95"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="240"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="108"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="118"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="136"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0007543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="290" mass="33287" checksum="6B463AF8113EB07C" modified="2023-09-13" version="1">MAERFLQDRATRLSSPTIQEDGDGDESGQSHPPPNYAADKVWNFLQPISASLFGHKDSANCILRAGPLKFYIHVPVLASRSPTFRGIFNEMIDKDAWGPRGDGSSDGSCEDSDMDTDDVLREGPSDQEMQESKDPNEDDDCDDDDDDDDGDDDDDGDDEDEDMPVLNIDLVDPVGSHFEELLRWIYTNDGERWMQCFTPTNYCNILQNICFLNIRTQEVLEICQRFEDSLVPEYDIRGMAVEVMERFVEAQQLLRQEQQQQQQQQLEQMELELELEKGQLQTEQQEQDQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MM94</accession>
    <name>A0A9P6MM94_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fungal lipase-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_004303</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002206">
        <property type="protein sequence ID" value="KAG0007738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MM94"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051218">
        <property type="entry name" value="Sec_MonoDiacylglyc_Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45856">
        <property type="entry name" value="ALPHA/BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45856:SF24">
        <property type="entry name" value="FUNGAL LIPASE-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fungal lipase-type" evidence="2">
        <location>
            <begin position="143"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="484"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="506"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0007738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="524" mass="60048" checksum="81AFD0ADC2B96A9D" modified="2023-09-13" version="1" fragment="single">MRTYSSATYYSRALRALLGGDERSLAEMSSSNVEVEVVENLFRETWESDSQGPSHNLFGFGASVLAFKGTESLGEFLRSLLAAVILICITTFLTRLEEAQADAAIQFHRNKNEKCGPACTKVCYRHEPTGEKCSKRCNRGCDTHAKYLDGGVHQGFYNLLFKSCPADKSHRYLTEGPVNVIAVILEKVLYEALEHDSGRWQTGLWITGHSLGGALASLVMARLQTIVREDDPLVRGLNKDAQERFTGSTVLSVMASQVINNFPAAHACESCVEPECESNDWKNCSKCAYCRMMRSKVRRRMDWVDKRRHCCIKLWDNKFKAACTGCKNFMDNEVNTTTCEKENEEKKCFCGECGNCDDCKRLESCRWCKMGSKNWPVVLRGCYTFGSPKVGDEEFAKTFDENQKLFVKRIENDRIEADKLDEDRKEADNENYRGEEYNGWDQEKIQADRREDIKLRFQAYWPVYWRIVNEKDEDYRHVGYRVQLPSDPKQPPIIAYPKVRSSTSESTHHSDFDKQERDRIKGST</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMJ9</accession>
    <name>A0A9P6MMJ9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_004644</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. MetX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002348">
        <property type="protein sequence ID" value="KAG0007447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMJ9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008220">
        <property type="entry name" value="HAT_MetX-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32268:SF15">
        <property type="entry name" value="HOMOSERINE ACETYLTRANSFERASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_1G15350)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32268">
        <property type="entry name" value="HOMOSERINE O-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000443">
        <property type="entry name" value="Homoser_Ac_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="70"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="136"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="324"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000443-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0007447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="382" mass="42219" checksum="2631732F78E2628A" modified="2023-09-13" version="1">MAPTTDPNIKYHQLGDFELQSGEILPSAYIAYRTYGSPSNPCVVYPTWFSGTIVAGNEWLISTSEHTRRGLDPERYYIVVPAAFGNGESMSPSNTTGPKGGVNMPKTTQYDNVRAQHNLITKGLGITDQIAVVGWSMGACQTYQWASQYPSMVKLAIPFCGSARTSLHNLAFLEGVKGAILADTEGYCGGRYMEEKGQQPVVGLKTLGRVYAGWGFSQAFYREKGFEKYFGLIGIEATMVGFWEKWSTSKDANNLLHMLWTWQHADISAQPLYAGESRLADADARLLDRGTGKPGAGNTLDEEAFERALKGIQAKVLIMPCSHDLYFPPEDSQIEKSYLGENGELKVIESIWGHWAGGPGDSKDDAKFIDDSIHDFFKKNRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MN42</accession>
    <name>A0A9P6MN42_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001934">
        <property type="protein sequence ID" value="KAG0008382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MN42"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="101"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="140"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0008382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="307" mass="34116" checksum="F6CA80A0A4421273" modified="2023-09-13" version="1" fragment="single">MSKRKAGEPSDPNSLPGSSYFLGIEPQNLNPRDYVEHRMKETPYLRIKDAIKEWHDWSQFFCEKPMWKDAFASVEVFTLNTYRTWQASTSKDPIRTRSLSKRAAVSSSTSASHTPNMEDLPLGLPSLPPPPPSPPPPILPSSSSPPLSSHQASSPASSGSSPSGSSSSQASTKSLPPAVLSQMRNDFTRSFNGYRGNQWKLSSGTIVDDVFYSYVMNMRSESSLHSLIITGEPDLEPFSPDDGLLIKEFLKESDLAHIDVCLSSWKKAELLQYQLGRDEMITLLKNGLGNLRPLEDNDIDKNEFDTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MN65</accession>
    <name>A0A9P6MN65_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DJ-1/PfpI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003687</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001996">
        <property type="protein sequence ID" value="KAG0008221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MN65"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052158">
        <property type="entry name" value="INH-QAR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43130">
        <property type="entry name" value="ARAC-FAMILY TRANSCRIPTIONAL REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43130:SF15">
        <property type="entry name" value="THIJ_PFPI FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_5G14240)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DJ-1/PfpI" evidence="1">
        <location>
            <begin position="26"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0008221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="152" mass="16654" checksum="B74D0D989064FAB2" modified="2023-09-13" version="1" fragment="single">MSPPPPPHGPLPKIPEGSGKLILGALVYDEMDLLDLMGPMRIFGEKLNTLDIQIIFIGTSMRPARSSQQVEVTPHYTLENAPKLDFFFTPGGIGSKAIWDNEEVMKLITERIKESTWCMSVCTGAGILAKTGLIDGYRATTNKAVFQFAANE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNL3</accession>
    <name>A0A9P6MNL3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003053</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001787">
        <property type="protein sequence ID" value="KAG0008790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNL3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0008790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="147" mass="17200" checksum="AAE6D2A32C21349E" modified="2023-09-13" version="1">MFIRFIRPSVPASIIDDRTESRNEDPDVDTDDDTNNNTNDNANDDNTHNSDIDVFEQGSFRDQLAMFNPQVYTQLQYERARKEEEERHHRKEQKKRDLNEAEEELSKNGCMIVELMNKKPETCSLEEMQAAVDSSKTLVQQLKDLFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNP1</accession>
    <name>A0A9P6MNP1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Armadillo-like helical domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_003916</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002069">
        <property type="protein sequence ID" value="KAG0008048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNP1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039868">
        <property type="entry name" value="ARMD3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013636">
        <property type="entry name" value="ARMH3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13608">
        <property type="entry name" value="ARMADILLO-LIKE HELICAL DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13608:SF3">
        <property type="entry name" value="ARMADILLO-LIKE HELICAL DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08427">
        <property type="entry name" value="ARMH3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01158">
        <property type="entry name" value="DUF1741"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Armadillo-like helical" evidence="6">
        <location>
            <begin position="449"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="608"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="738"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="609"/>
            <end position="624"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0008048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="805" mass="89758" checksum="9AEB77B00AFAF5E9" modified="2023-09-13" version="1">MKLKEKFVEIYDTFLRGQDPAQGKDPDVFWDELFLIKINEEYLSTSLRQINEDQLLAIKDRINSIFLHAVQAMRDPLPQRRLHAMQTLTIVLGEIFRKKFHNWSFDVIHLLTGLTHADLVFRTLVQGINDILGGDESLAIKVVALRLAVALACGNDNVNKNSLNEYFMQKDIFASLIKVRELSLFDLGTNRMTRADQNLKNLLQFFVMVDSVDLAFEAMALLGLLANYNKYEIQNPYLAHLATLNDDSVFQKMAMVIVHTCDSMRRGYMEVIDDDEMSAMSKLTSALSYVTGMLWNPKAQDSSVTDAAFGLLPDGRVTLMLVFYDLVNSNKRFLHVFLNYSTSKAAAAAASTNPQAKPAEQLTPETTETGLGSFLSFSSYLLQHNRTHRTTPYAHLCLIIMLILVEDPNSYPLLCIIPLSQDQPSAPSANSVSPIVSVRLCRQRQPVLPMVKQARPMAAVLLDVILGFLKHNMKKKLQIDCFRIAIAILFSLASRFKSLRVRLPYHWVEVWNTLQGLVKFLQSNAKVFEHHQDARDLVAETIDLVNYFVTYGDLIMPDPASLYALYYEIVRSGIEPFTDLTEQFSFEVLPPLPAPLPHHDLTSRNRLNLASSPTTTTPPGSALPSPTPSPGPGATSMIGSPPMSPYQSYSGFRSTSPAAASVSSALQQQRMIIIDLSNINQVYTFFFTHLLAWRDANPTRSLGPDLVSTIIKNHYQDLTLTPIPLDAFLTQQRQANASGLGMRGGAASPGPTGGSGPHPGWDGYSEVPGKVHFFRQLTRFVVADLRDVSRQHAAQQGKTSMTTMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MP45</accession>
    <name>A0A9P6MP45_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">rRNA adenine N(6)-methyltransferase</fullName>
            <ecNumber evidence="10">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">DIM1</name>
        <name evidence="13" type="ORF">BGZ80_002743</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>adenosine(1779)/adenosine(1780) in 18S rRNA + 4 S-adenosyl-L-methionine = N(6)-dimethyladenosine(1779)/N(6)-dimethyladenosine(1780) in 18S rRNA + 4 S-adenosyl-L-homocysteine + 4 H(+)</text>
            <dbReference type="Rhea" id="RHEA:42780"/>
            <dbReference type="Rhea" id="RHEA-COMP:10234"/>
            <dbReference type="Rhea" id="RHEA-COMP:10236"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74493"/>
            <dbReference type="EC" id="2.1.1.183"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="8 9 10">Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="10"/>
    <dbReference type="EMBL" id="JAAAID010001690">
        <property type="protein sequence ID" value="KAG0009101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MP45"/>
    <dbReference type="OrthoDB" id="74991at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052909">
        <property type="term" value="F:18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.480:FF:000002">
        <property type="entry name" value="rRNA adenine N(6)-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000007">
        <property type="entry name" value="rRNA adenine N(6)-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001737">
        <property type="entry name" value="KsgA/Erm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020596">
        <property type="entry name" value="rRNA_Ade_Mease_Trfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020598">
        <property type="entry name" value="rRNA_Ade_methylase_Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011530">
        <property type="entry name" value="rRNA_adenine_dimethylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00755">
        <property type="entry name" value="ksgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727">
        <property type="entry name" value="DIMETHYLADENOSINE TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727:SF7">
        <property type="entry name" value="DIMETHYLADENOSINE TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00398">
        <property type="entry name" value="RrnaAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00650">
        <property type="entry name" value="rADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01131">
        <property type="entry name" value="RRNA_A_DIMETH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51689">
        <property type="entry name" value="SAM_RNA_A_N6_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 10" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5 9 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 9 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ribosomal RNA adenine methylase transferase N-terminal" evidence="12">
        <location>
            <begin position="56"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="11"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00061109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0009101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="325" mass="36650" checksum="00BE73641AD8D6C2" modified="2023-09-13" version="1">MPKVVTKKFSQRTEKKGDKKDEKAASSASAASAASRAFGPLFNKDLGQHILKNPLVAQGIVDKAYLKPTDTVLEIGPGTGNLTVKILEKCKKVVAVEMDPRLAAELTKRVHGTPDQRRLEIMIGDFMKTTLPYFDVCISNTPYQISSVLVFKLLEHRPIFRTSVLMFQREFALRLVAKPGDSLYCRLSVNVQLYAKVEHIMKVGKNNFRPPPQVESSVVRMEPRNPPPPVDFKEWDGLMRILFVRKNKTLSASFKTDSVMEMLENNYKTFCATHDRMIEDPLDMKAKVQAVLTNTGLAEERAAKMDQDDFLKLLAAFNEEGIHFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MP94</accession>
    <name>A0A9P6MP94_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PAS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001806">
        <property type="protein sequence ID" value="KAG0008735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MP94"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="190"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0008735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="386" mass="43647" checksum="92B6E702D1FB5C68" modified="2023-09-13" version="1" fragment="single">EFERISRHHKTVSAGTWNPTSLNLELRACLLLNRFTRNLSVMYASPSCQLIFGIDPDDLLGKPILLYIRADEIASFVEQGDRARSSSSIRHMRFWFQSPNCHEEIPCEAVFYGASDALIMILRKCLPFKRRQLITDSNPSSSSRRLSAYSDMANWRCSSDLDSDSEDSRPYGRFQNTHSIRGDTTETVESTDSQSMYSSSLDESLSSSFTSFQSTASQDSRGARVHRASLGGISVGSISTIRNLDREQHRLRPLTSLQEENSDIAETGDTLTAGYLLREFNSQELEVIESEVEEGIEEMNLRSGYRSDVLEDEEAMFYSEEEYRSEGNHYSEGRHYSKGKYYSGEHYSKENHYSKGKHYSEGENHFKANYGGGIGGTAESGEMEVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPR9</accession>
    <name>A0A9P6MPR9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Alpha/beta hydrolase fold-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_002492</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001618">
        <property type="protein sequence ID" value="KAG0009331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPR9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF8">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="2">
        <location>
            <begin position="1"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0009331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="235" mass="26814" checksum="BE52718F4EB87CFD" modified="2023-09-13" version="1" fragment="single">LAPQKKFPSQRDQYLSAYNFLINEIKWNPNKIIFGGDSAGGNIVLNACYSLRENQLTLPRAIICLSPWVRLDADETTSPSMAHNSNTDYMPAHVFKKIAGSYAGSREIGDPRISPFYVRDHSGFPEMAIIYSSSEVLRDDCARFVDVYQTTGGRVTLHYEREGMPHVYPVLRELGGKTAVKDAERRLMEWINMIVEENRVTFDSRRHPDAIPQHYSAPDDFELHEVVTEKPSRYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPV2</accession>
    <name>A0A9P6MPV2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Pre-mRNA-splicing factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_003140</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in mRNA splicing where it associates with cdc5 and the other cwf proteins as part of the spliceosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Belongs to the 40S cdc5-associated complex (or cwf complex), a spliceosome sub-complex reminiscent of a late-stage spliceosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CWF11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001812">
        <property type="protein sequence ID" value="KAG0008712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1879at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005684">
        <property type="term" value="C:U2-type spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd17935">
        <property type="entry name" value="EEXXQc_AQR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000507">
        <property type="entry name" value="Pre-mRNA-splicing factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:003210">
        <property type="entry name" value="RNA helicase aquarius"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048966">
        <property type="entry name" value="Aquarius_b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048967">
        <property type="entry name" value="Aquarius_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032174">
        <property type="entry name" value="Aquarius_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026300">
        <property type="entry name" value="CWF11_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF5">
        <property type="entry name" value="RNA HELICASE AQUARIUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16399">
        <property type="entry name" value="Aquarius_N_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21143">
        <property type="entry name" value="Aquarius_N_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21144">
        <property type="entry name" value="Aquarius_N_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038901">
        <property type="entry name" value="AQR_cwf11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="1" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNA helicase aquarius N-terminal" evidence="5">
        <location>
            <begin position="56"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="domain" description="RNA helicase aquarius beta-barrel" evidence="6">
        <location>
            <begin position="525"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="domain" description="RNA helicase aquarius insertion" evidence="7">
        <location>
            <begin position="739"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="3">
        <location>
            <begin position="846"/>
            <end position="1148"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase-like C-terminal" evidence="4">
        <location>
            <begin position="1157"/>
            <end position="1349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="790"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1391"/>
            <end position="1424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1463"/>
            <end position="1515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="21"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="799"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1410"/>
            <end position="1419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1472"/>
            <end position="1490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR038901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF21143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF21144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0008712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1515" mass="173307" checksum="DE55067F7B4757E6" modified="2023-09-13" version="1">MSPNETQEGAQQSTQDVNNDQQQAMSQVQSQNGTNAGAYRPTVKEMQNDSVATLAEAWTKGEKAAQDYDAEVVERVYKDELVKNNFSITKLTLLEVSQYLEKYLWRHYDPSQSPTIHVLSIVLMVNEKFRSRVEAWGAFEELPDHFPAFFGEVLRLCLQDSDDVDLRMKRYLLMFIINCFQSLENPLIRSECMRLVSLSTWHSLVSSEKRDVEFKEYPQLLKFWKHLEKKFSALDSDQQQKAVFERSWLSEMMKNFVRILETIDDSDQEKIAYCERFMEFLIDLEAQLPTRRYFNTLIDDHQIVAICKLSKFANNKKTGTLFGQLLDILAFYTGFEINSHTGLALTKEEMTEIHASKLTKLQRIAFTSFKDELIDLAMTNLRAIEDRKSLSKHFENLTQEQLVQLCGLLNIRTTKITDPSVEHSREMLLEVLFIQFEKRHSQIEQINALPLYPDEHALFEDAAVKEEMYNAERPLALPKLNLQFLTLHDYLLRNFNLFRLESNYEIRQDIEDAVVRLGPRPGPTEGTTAFSGWSRVAAPITSFRMVELAKPNLGEDRLSLITADVTFNVRKYTDAIQAEWEAIREHDILFLLTIEAHDDIDEQWDGKVSFRKHYGLKYVRGCEVVSVIGPNGKPFDYKKSDPQMIQDHRTGNTRTFRVALDANQYKIDQSNAHTNGTPDVYQTFNIVLRRKPQENNFKPVLETIRDLMQSDLMVPEWLHDVFLGYGNPNSAHYSQLQRQVREIDFRDTFLDLDHLKESFPGMTVKAKDGDESILAAPFVVSFPGAPEAAAAGTKKRKGAEKSKKEKSNQEQEQAQDELIVSTYKTPNMGPYPEDIPNRNQVRFTPTQVEAIKAGTNPGLTLVVGPPGTGKTDVAVQIIANLYNNFPNQHTLLVTHSNQALNQLFEKIIALDVDERHLLRLGHGEEELNTELSFSKYGRVTSFLEKRVSLLAEVDRLAQSLEIGGEHGSTCETAGYFNSYHVVPMWKEFERQVNSKEEAERSKELVEGLFPFSVYFSNAPAPLFSDCTSFDDAMEAARGCFRHLAKLFEQLEEVSAFELLRTSYDRANYLLTKEAKIIAMTCTHAALKRRELVNLGFKYDNIVMEEAAQILEVETFIPMLLQEPEDGVNRLKRVVLIGDHNQLPPVVKNTAFQQYGNMEQSMFTRFVRLGVPAIELDAQGRARSDMADLYKWRYKNLGDLPNISERDEFKFANPGFLYDYQFINVNNYKGQGETAPRPHFIQNLGEAEYVVAVYQYMRLLGYPAEKITILTTYNGQKDLIRDVLNQRCSWNPIFGRPARITTVDKYQGQQNDYVLLSLVRTKAVGHVRDVRRLVVALSRARLGLYIFGRQKLFQDCHELEPAFKRLLKRPTKLWLKTGEMYPNTVRLVDIESAGEKEEGDAGDEEAEKKSGSKKKKKSKKAKADEEAAKAEADAEARKNYEIEDVGQFGEYVFGMMKEQQQYAVQQQKAYLQSLQPPSDSPINSEVPTTSGVVAADADTEMGESSAPDSAMDVDQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPV5</accession>
    <name>A0A9P6MPV5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome b subunit of succinate dehydrogenase, Sdh3p</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">SDH3_2</name>
        <name evidence="9" type="ORF">BGZ80_002905</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001741">
        <property type="protein sequence ID" value="KAG0008929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPV5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006121">
        <property type="term" value="P:mitochondrial electron transport, succinate to ubiquinone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03499">
        <property type="entry name" value="SQR_TypeC_SdhC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1300.10">
        <property type="entry name" value="Fumarate reductase/succinate dehydrogenase, transmembrane subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034804">
        <property type="entry name" value="SQR/QFR_C/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018495">
        <property type="entry name" value="Succ_DH_cyt_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014314">
        <property type="entry name" value="Succ_DH_cytb556"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000701">
        <property type="entry name" value="SuccDH_FuR_B_TM-su"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02970">
        <property type="entry name" value="succ_dehyd_cytB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10978">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE CYTOCHROME B560 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10978:SF5">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE CYTOCHROME B560 SUBUNIT, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01127">
        <property type="entry name" value="Sdh_cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81343">
        <property type="entry name" value="Fumarate reductase respiratory complex transmembrane subunits"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01001">
        <property type="entry name" value="SDH_CYT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="165"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0008929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="186" mass="19734" checksum="312DD8C3969CE470" modified="2023-09-13" version="1">MLAHRVARTPLSAAGTSMQFLAKSKTAVYKAHVMAPVGTRILSTSQSDPKKVVVAPIIQQRKDRPLVPTFSIYEPELTWCLSGLHRVTGAAVAVGFYGGAIAYTLGPLFGLGFDSADVTSMIATIPDAAKIAGKFVIAFPFTFHSLNGIRHLIWDTASALTLKGVYTTGYTVMGLSIASAAILAFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQI2</accession>
    <name>A0A9P6MQI2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pentatricopeptide repeat-containing protein-mitochondrial domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_002379</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001584">
        <property type="protein sequence ID" value="KAG0009451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQI2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031930">
        <property type="term" value="P:mitochondria-nucleus signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057027">
        <property type="entry name" value="TPR_mt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47936:SF1">
        <property type="entry name" value="PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN GUN1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47936">
        <property type="entry name" value="PPR_LONG DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01535">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13041">
        <property type="entry name" value="PPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13812">
        <property type="entry name" value="PPR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23276">
        <property type="entry name" value="TPR_24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="115"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="Pentatricopeptide repeat-containing protein-mitochondrial" evidence="3">
        <location>
            <begin position="309"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="413"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="448"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="483"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0009451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="548" mass="61405" checksum="6A78CA7DF10AC1AB" modified="2023-09-13" version="1" fragment="single">MLMRYSISRSAGLQHFTQKFNRIHISKYNICTRQQPQHRYSGPHSISSHCQATTTPGARQGVAGVYSRGIITDTYPSTQLHKFNRKLVDLVRDPQACMVIFDKCRDILELNLKPDQTTYHVLLEAYARNNDLDNILRTFEEMSLVGIPPNITAYNIGLRVAATHGDTVMLERIKEQIENAGLKMNLNSYEIIIQGLCVNQELEHALDLLGDMTVSVNEKGLPDENGKPVIDVRPSLSCYKPVIDLALSLHESETAYLVLKMAEIQSGLSKIPAVIYIDVMARAAEDYVLNAVEYCWRKSVNELGACPDEGTCMLALNCAGHEKAPRLAAEVIQYMGENKMEFQEYHFAPLLQAFSLAKKFKSAFNVLSIMRASGMKPTILTATSLLKVLDEPENIEEAFISMQEMHREGKKVDVVAFNILIEACGRINELTRAMTIFDAAASLGVETDTNTYNALLTGCITDRNMVEGKNVIAMMQGAGVDPNVDTYQSLISLCLTQINYEDAFMYLEEMKSHNVIPSEPIYTSLVRKLARENDPRIKYAIEEMESFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQU6</accession>
    <name>A0A9P6MQU6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_001714</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001398">
        <property type="protein sequence ID" value="KAG0010168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQU6"/>
    <dbReference type="OrthoDB" id="2373827at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0010168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="149" mass="15694" checksum="76702CB5A795D7EC" modified="2023-09-13" version="1">MGILSPVCMTSDGTRLYAFAYGSNGSGRSFSYVLIKSNSVPSYTLNDLSWTLVSTLGGPNVYSMSLNAYSCVVDDMGVFTIVSSAFNGTGTASKGMTLGLQYQPPGDTSGGSGTWSNVYAPSGYTYSSTNTLFFLKDSSGKDTLMKAYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRE6</accession>
    <name>A0A9P6MRE6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SGNH hydrolase-type esterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001919</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001458">
        <property type="protein sequence ID" value="KAG0009930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRE6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004622">
        <property type="term" value="F:phosphatidylcholine lysophospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00229">
        <property type="entry name" value="SGNH_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051532">
        <property type="entry name" value="Ester_Hydrolysis_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30383:SF5">
        <property type="entry name" value="SGNH HYDROLASE-TYPE ESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30383">
        <property type="entry name" value="THIOESTERASE 1/PROTEASE 1/LYSOPHOSPHOLIPASE L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGNH hydrolase-type esterase" evidence="1">
        <location>
            <begin position="10"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0009930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="210" mass="23486" checksum="39E557C35FDE6EF0" modified="2023-09-13" version="1">MDPLPINVLCLGDSLTNGHIRARAHTPYSDHIQSLLNGNGQNHVTLFNAGVDGDTVPRMLSRLPTLLQQVQFHHVIFLGGTNDLAFVSNAGDITPEQATAHISFKPIYDILVAQQSIKSFLHLTVPYNTFDRLDPGYKSYKDALNNRIISDPCPKKSLLDLNNPALNFNHLLMTEDERDELWSDALHYSSLGYKRLAACIYTELNKMLVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRX2</accession>
    <name>A0A9P6MRX2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_000634</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001134">
        <property type="protein sequence ID" value="KAG0011508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRX2"/>
    <dbReference type="OrthoDB" id="2449920at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="134"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="275"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="19"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="182"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="291"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="305"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0011508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="374" mass="38720" checksum="90DABDEF452D9DA2" modified="2023-09-13" version="1">MALVAPTTAPITEAPPPTTTTEAPTTTTTEAPVTTTAAPPETTTTNVPTSDASPATTTTDGSVANPSPSPDQSGNGGGSSGGKATKTKSSVRTATGSGLYPTQVSGSVGNSTGSDTANSISGGPSDNDGSSKSLAGPIVGGIAGALVLAFLVAVFVMRYRKKSKARQRRLDILLDPEQAQALGLSGGSNASGKPRPTSVNSPIPKPSTQLEMAPITSGPAPPGAGGPIHHSDGGYNGYDYQQGYQNVSYGGYQDQYEQYDQYDPYYQQPIPTAQPVMGQLQPTGYYPDSPRQQQQLAHLQQQRQPYGSGSPSICHSSPASQNAYPQQIYATGSSPLVPHQQQAAPAESYERFNKVESSDYIASQSPARNPQIIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MT36</accession>
    <name>A0A9P6MT36_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">SURF6-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_000376</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SURF6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001076">
        <property type="protein sequence ID" value="KAG0011858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MT36"/>
    <dbReference type="OrthoDB" id="444809at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029190">
        <property type="entry name" value="Rrp14/SURF6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029188">
        <property type="entry name" value="Rrp14_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007019">
        <property type="entry name" value="SURF6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14369">
        <property type="entry name" value="SURFEIT LOCUS PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14369:SF0">
        <property type="entry name" value="SURFEIT LOCUS PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15459">
        <property type="entry name" value="RRP14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04935">
        <property type="entry name" value="SURF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribosomal RNA-processing protein 14 N-terminal" evidence="6">
        <location>
            <begin position="13"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal RNA-processing protein 14/surfeit locus protein 6 C-terminal" evidence="5">
        <location>
            <begin position="191"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="39"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="168"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="322"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="93"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="198"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="231"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="322"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="384"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="406"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF15459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0011858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="415" mass="45833" checksum="81DA3B9167A0F145" modified="2023-09-13" version="1">MSTSFTLDGLEERIKAHGSSFDSLLKLIPAQYYITKELTEEEQNSKYQHNKKRNAPKQEIKERTKKAKKAKLDPENNKSVMDIQSEMATQASDNEDDDEDDEEDGDDDVNMAGSDDDVAEDDSEAPVIAKSSTHNFEGLLAQVQTAAQTPAQAPKSITELRAKLEERLSKLRGRRGANDPNGASAKPISRQAILEARLKRKKDKKASRKLAKEKLAAGGSEGLVVKEHAAPTSSGRPSASSINEKGEVRFSKFEFEGLQKKKRGPTDAQGQLKMVEAHKEKLAALQVSDPEKANALKDKDTWRKALQLAQGEKVKDDVKLLKKTIKREEIQKKKSSKEWGERKSTITKAKDQKQKKREENIKARIDAAKNKGKKGDKKGDKKGKGAPKGGKGGKPKARAGFEGKIGKKQSKPSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTI9</accession>
    <name>A0A9P6MTI9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">AP-3 complex subunit beta-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">AP3B2</name>
        <name evidence="8" type="ORF">BGZ80_000116</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the adaptor complexes large subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001018">
        <property type="protein sequence ID" value="KAG0012223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTI9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030123">
        <property type="term" value="C:AP-3 adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026740">
        <property type="entry name" value="AP3_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026739">
        <property type="entry name" value="AP_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11134">
        <property type="entry name" value="ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037096">
        <property type="entry name" value="AP3_complex_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Clathrin/coatomer adaptor adaptin-like N-terminal" evidence="7">
        <location>
            <begin position="46"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="279"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="612"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="720"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="293"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="612"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="740"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="772"/>
            <end position="830"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0012223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="843" mass="94705" checksum="195C09E305C81FC9" modified="2023-09-13" version="1">MYNMDAYLKTLTSNAVKLSKKMQDNLAEGTRDFRFENQAHFLDTNEDKMREIRKNLDSKYEKEKLDGLKRLIAMISKGRDVSEFFPDVVKNVASNSLEVRKLVYIYILRYAEQEQDLALLSINTFQKDLSDKNQLIRAMALRVMSGIRVPVISPIVMLGIKKCVTDLSPYVRKIAAHAIPKCYQLDPAQKDALIDIISTMLGDNSTYTIGSVIMAFNQVCPDRLDLIHPQYRKLCKMLVDMDEWGQITAMDLLLRYSRTQFLNPIGKLSATPTTRVKKEKSNVKSFYSDDDSDVSHHSSRSSDSESDDENNSVDPDLAFLLKCALPLLQSRNSQVVLSVAKLYMHLAPAQDSYKIGRPLIRLLRTHREIQYVVLNNIVAIASQRPYVFDQFYQHFFVRSTDPAFIRNLKLDILTLIASESNITFILRELQEYVKSSNKDFVTQAIEAIGRCASNIPAMAESCLGGLLKLSYSKSDSVAAQSVVAIRRLLQQRPGDCIYMITQLTKALDEITESLARANIFWLVGQYCSQLSTVAPDVLRKAAKSFCSESESSKLQILTLGGKVVAQEGTSSKTINLLFQYVLNMARYDLDYNVRDRARFLRVLVYGEQKSKKISSGDHGQEVHEDEDHEEHEDQVEDVGGFEYNEKELKLSDHVKAILLSDKPAPVQENPSHGREQYKIGSMSLVLNRAVAGYEPLPDWPTTQPDPSVRRLAATMEAPGYMNDRTGFGSDSVYAQSRQGQSGGFGGSGNNGSRYGQTTAGPGAQSLDKFLESSEEETDSSDETDSDEDETSEEEDSSGEEETSEEEEDEDEEEEEDDGDKDEGSSSEEEAILPPSSKRSNSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTS2</accession>
    <name>A0A9P6MTS2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_011084</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000847">
        <property type="protein sequence ID" value="KAG0013434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTS2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0013434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="83" mass="8936" checksum="2EA0E8DA62E84353" modified="2023-09-13" version="1" fragment="single">MGREHQGENNEGAKSHSTTTSNLLNLTISDKPVSPECVLQALPKGRDGLRRGSLGTVVLSDEETLPYMSTEDAGPLSSMEYTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MU96</accession>
    <name>A0A9P6MU96_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Annexin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_010871</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the annexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000804">
        <property type="protein sequence ID" value="KAG0013766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MU96"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005544">
        <property type="term" value="F:calcium-dependent phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001786">
        <property type="term" value="F:phosphatidylserine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.10">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018502">
        <property type="entry name" value="Annexin_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037104">
        <property type="entry name" value="Annexin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10502">
        <property type="entry name" value="ANNEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10502:SF102">
        <property type="entry name" value="ANNEXIN B11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00191">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47874">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51897">
        <property type="entry name" value="ANNEXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0041">Annexin</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0013766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="366" mass="41337" checksum="AEB39601376F7B61" modified="2023-09-13" version="1">MAPAIPPEILHDIESIHMALNYSVPDVEALVNIIGTFHACVVQFNPRSRSTPSPEKNVNFSEQNQAKTQLIIDFDYMYHPTTLIGRRENHQLIAIARQYKAAFGVDLPTELDRRIIGSVGSLLSYACMHKVLAEAHYLHNAGKSHRKYETLRKKDTVAEILVGRTPEELRELHEAYKALYKGDLKEHVLSLCKDDIDKDFFSGILLDKEDKPLENVEGAIKAFNKLLVAQDLSGSLHYVSTLTTSQVRTLVKSYNEHFKEAHVVSTIEKTIGHKHKREHVEILLFAVMQASGPSRHVALLFEESMAGVGTNEDQLSRLVVIHRGKFMDEVKLSYSVDFDRTLADRIRGDTSGPYCNLLCHLINQTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUS1</accession>
    <name>A0A9P6MUS1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Guanine nucleotide-binding protein subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">GPA1_4</name>
        <name evidence="11" type="ORF">BGZ80_010575</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000750">
        <property type="protein sequence ID" value="KAG0014223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUS1"/>
    <dbReference type="OrthoDB" id="5817230at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005834">
        <property type="term" value="C:heterotrimeric G-protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001664">
        <property type="term" value="F:G protein-coupled receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031683">
        <property type="term" value="F:G-protein beta/gamma-subunit complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007010">
        <property type="term" value="P:cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007186">
        <property type="term" value="P:G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000750">
        <property type="term" value="P:pheromone-dependent signal transduction involved in conjugation with cellular fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00066">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002307">
        <property type="entry name" value="Guanine nucleotide-binding protein G(k) subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.400.10:FF:000007">
        <property type="entry name" value="Guanine nucleotide-binding protein subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000692">
        <property type="entry name" value="Guanine nucleotide-binding protein subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.400.10">
        <property type="entry name" value="GI Alpha 1, domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002975">
        <property type="entry name" value="Fungi_Gprotein_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001019">
        <property type="entry name" value="Gprotein_alpha_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011025">
        <property type="entry name" value="GproteinA_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218">
        <property type="entry name" value="GTP-BINDING PROTEIN ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218:SF302">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-5 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00503">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00318">
        <property type="entry name" value="GPROTEINA"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01241">
        <property type="entry name" value="GPROTEINAFNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00275">
        <property type="entry name" value="G_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47895">
        <property type="entry name" value="Transducin (alpha subunit), insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51882">
        <property type="entry name" value="G_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0519">Myristate</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0564">Palmitate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0807">Transducer</keyword>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="43"/>
            <end position="48"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="150"/>
            <end position="151"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="175"/>
            <end position="181"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="200"/>
            <end position="204"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="269"/>
            <end position="272"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="325"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0014223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="353" mass="41087" checksum="AB9C9D9A67C66475" modified="2023-09-13" version="1">MGCCVSQEDKEGRSRNEVIENQLRRDRMQMRNEVKMLLLGAGESGKSTILKQMKLIHDGGYTKDEREAYKEIIFSNTVQSMRVILEAMEKMELPLYHEANRNYGIIIMSLPPQIEGEYMPHEVAVAVQNLWVDPNVQQAFQRSREYQLNDSAKYYFDSIERISKSNYIPTDQDVLRSRVKTTGITETRFVIGDLTYMMFDVGGQRSERKKWIHCFENVTAIVFLVAISEYDQLLFEDETVNRMQEALTLFDSICNSRWFVKTSIILFLNKIDRFKEKLPISPMRKYFPDYEGGDDYDQASQYILNRFVSLNLSDTKQIYTHFTCATDTSQIKFVMAAVSDIIIQSNLRDCGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MV07</accession>
    <name>A0A9P6MV07_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Kelch domain-containing protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">KLHDC3</name>
        <name evidence="3" type="ORF">BGZ80_010892</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000809">
        <property type="protein sequence ID" value="KAG0013727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MV07"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093:SF18">
        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00612">
        <property type="entry name" value="Kelch"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0013727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="346" mass="39587" checksum="83F5F6BA197189FC" modified="2023-09-13" version="1">MTTLTFRQVETLDPSTQPLPRQGHASVFHKGCLYVFGGRVQGSGRIYVNDLWKYDTAQNRWEELIAADPSHMPRKRHNHSCVVEMNAIYVFGGQTVSDEYLGDLWRFDLDTRQWSELATSQPRHSHSALKHERSMVIFGGRTGLKPAVYSNEILVYDFDSNAWDSLYAGDDQNPTTVAPHPRSYTSIVQCGQYLVVFGGYWWNGKEHYFDDTFSFCLNSHEWVKLSPLRDERVPHRRNRHSVLSLPATDVGSMSGMIIFGGNYYGNRRATDKFFGDAWLFGSLMGESLTSGRWSKVTLLGDIPCPRGHHTWVNDDQDTGRTWMFGGEANRQRFNDLYEVRVEVPAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVG2</accession>
    <name>A0A9P6MVG2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BGZ80_009962</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010000646">
        <property type="protein sequence ID" value="KAG0015237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVG2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045719">
        <property type="term" value="P:negative regulation of glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14004">
        <property type="entry name" value="STKc_PASK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000320">
        <property type="entry name" value="Serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000314">
        <property type="entry name" value="Serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF51">
        <property type="entry name" value="PAS DOMAIN-CONTAINING SERINE_THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="7 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="14">
        <location>
            <begin position="712"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="134"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="619"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="138"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="619"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="646"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="667"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="745"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0015237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="981" mass="108704" checksum="08577681520442E3" modified="2023-09-13" version="1">MPLASSATPSSNPTNDPLQGSSSNGSVPPRPPIMASTSDELAKFSNESLHSYSFTNGTHDKTFVEGRRSIFYRSIDFMKQKIKGWQVPISNVFPTSPSTTPTDNFSIGAYPSPPNPFSSIFADSADINQKPKLKRTMTDVSSKASSELQQTKERPPRPLSVATISTAGNYSSLHSPTRFVPQNQAMITTDRNWNIVMANDVSSLVFGYHGSELASMSILDLTASPYKEKLEALLQQLQDGSSDGKDEHVLLCGKVIRIQKRNSHSAAASLWLKQRKDPNGKLVYIWVFEEISESVVSLVISSSGEILNIEGAIELYDYDYMELLGRSVTTLIPALEKLQTVDPDTSFATLDVNQINVIKFFGSRTKNGSTFPIICKVLNPSEQIDPEANPFNLDEDSMDGYLLRIISMPAIAGVITTHDSGLIQSANTVFTKFLFGYPATELNGKRSINDLIPQFQPILDKLLDDADKPQGGDYVHLTEGAVVTATIIRRTAAEAEKPSILSPDFFAKPQDGSSNSSASSTSNKQSLVFKRNFGMSALRRPNNHFVSNSGIVALHRDQTPLDVDIQIRMIESPQGRLFAVWITYDREISFTREPNRKAVTPSLTPVQYIASAMEGVLPTGTSDSNAEQVVPDTNKTNNVSIKNGLSSKSSKSQPPSVKTTPNRHLSSDSGSSPSSCASPSSPAPSTPSSRLSIDMIKSQYSAVTHQHSITDYDILDSLGQGAYGQVKLCCLKNGSNKVVMKYIVKSRILVDCWTNDRVLGMIPMEVSIMHTLRMIPHPNIVHMTDFFEDEEYYYVEMTLHGTGMDLFDYIELTPYMTEDEIRAIFKQVCDAINHLHSNKIVHRDIKDENVILDQKGNIQLIDFGSSAYLKEGRKFDTFCGTLDYAAPEVLTGKKYEGRKQDIWALGILLYTLIYKENPFYNIDEILSRDLRVPFVLSEDSIGLIRLMLSRDIEKRPFIEEVLAHPWMTAPPKTQEPAKVDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVI9</accession>
    <name>A0A9P6MVI9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glutathione s-transferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_010475</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000731">
        <property type="protein sequence ID" value="KAG0014392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVI9"/>
    <dbReference type="OrthoDB" id="414243at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050213">
        <property type="entry name" value="GST_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571:SF150">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14497">
        <property type="entry name" value="GST_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="48"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="2">
        <location>
            <begin position="131"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0014392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="269" mass="30425" checksum="ABCFED66E043FB25" modified="2023-09-13" version="1">MTDTTATTTPSLHHTFTTKTRPELANAAGTIIRIAPDKSDRDHDQSDVTYKILYLKLHGLAATTRIILAVAGVQWESIYPTDWNNEKQNVPLGVLPVLYEHHASTGLVIEIPESEVIERYLARKFGLLGRDAWEETAINVFYSSSNAIMSLYVNKVLLAFPDTKARELAKFVERDVPAWIKQHEKWLMKSDGYYVGDQLSLADIRSVVCLDRFLTIPECKEMFSSSLTPGLFRLKRTLETNTRYSAWIASDEFEAINISTRQRLAVLSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVQ6</accession>
    <name>A0A9P6MVQ6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_010414</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000721">
        <property type="protein sequence ID" value="KAG0014494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVQ6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="3">
        <location>
            <begin position="127"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="177"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="456"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="518"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="558"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="632"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="150"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="24"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="39"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="85"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="115"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="183"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="222"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="295"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="336"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="380"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="559"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="576"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="632"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="675"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="701"/>
            <end position="711"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS00036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0014494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="718" mass="77793" checksum="FED6801735F9DB78" modified="2023-09-13" version="1">MEYLQGMHPIHHGHARQSAGGGSSTTTGSTTGNSYGYNTAGGSGGSTTSGGHHFYSQQHHSSGPGRANLNAAVNQHQRQVHEPGSSPNSSGTSATGPSPRTAGERNGSGGGRSGSSGTEQQGRNSTKRAAQNRAAQRAFRQRKDLYVRELERKADLLQQAEGKIMALSARNRELELALLAQGVPPPSQQPQQPQPQPQSQSQPQPPHHASVAPASGPTGQSREQDREPIDYNRERGREERAPIERRGSQDAYENCISSHPAISRHASSHQLHHAFNSASPLLANGSLEHQPLSKQHQQQQQQQHQQQQQRQRPESDYGFDGQDNNPHVRLHRHPSESSLRTGRGESNSADSGDDYGAGRASQYTRRGSSESKNEYSQSSARGSHQNNSMIPEYSEIFPPSARSWSYQLEDGVKPHSPMTAAASSPIVPGGIVSATSTSGNGYVDHPGTRAEMEYLSDERSSEPGSGYDSVNKRPSDGAISWTSNTSTGTIGGGHEGNYTSRGFQEHVNGEVRKQQSWSSFSATRNGPSLINAPSTPSPMTTAVREGINDMDTQDSFHQQQHRMLHHRASTGSVSIRDTDRQHPRENQSRMIMSDSPEMSPLDGRLGSSVAAAAGNTSPQMSRHQHQYFPAIGQQQRQQGLQQSPGQEHPPGAYGNSPRSHLYQRHYRQAQGLNDSGEKLGRHPDAANSDMDTVYDQPRDIGNGNNNGAGYNEASTRSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWD3</accession>
    <name>A0A9P6MWD3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_009903</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000636">
        <property type="protein sequence ID" value="KAG0015355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWD3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="432"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="312"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="364"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="35"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="331"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="373"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0015355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="471" mass="51674" checksum="D822B25BB8165C62" modified="2023-09-13" version="1">MTTSSVLTPPYSPFLVPSDMRNTKTLAFAAPPPLSSSSSEISESASAPASGTSTPTSSTTSSLLPHDPSSNNPFSRILVLYHKATSTLLLRQLAIAYSTCVEALELLATTNKAYGLDQVTESLSTRRSYFLLKQKLWILNITVFEAMLSDRVEVKHDIANRGRAGLRRRLLGTSKENPEKLIKDLWRRVMEDYGGLEGDVDGQVMVAFTLLCINQKLHILARQATEAYLATIPEGMLIHLEAAAGALTIVQRGIKDPLMVQYERLIELYVVHVLSKLHEWEYARQFLESNSVLSDSTKQVYSTILNRLQKKSTRPKKAVVKDHTAATLNPSTSASSMASTSSSVNLGSVKASILSPVATSKMESTLPKKEVNSPGSLTRAHSQGLPSKEHVSAGLVPSRTTMGEVSASTFQGRFWILLQHYVDQIRSARSRIGANQMMVIVGIVVFLSTLSQSRLRASNAMQIVVERLMQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWF4</accession>
    <name>A0A9P6MWF4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_009329</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000548">
        <property type="protein sequence ID" value="KAG0016269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWF4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="226"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0016269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="380" mass="40850" checksum="59521BDC681B4D95" modified="2023-09-13" version="1" fragment="single">MTGDDMTTCEAAKSGYPVVLLMNVLIAIMNDGYSESRDEGQLAWLKQWSLVIVETELSMMGNTTRGSRDLFPDYIYYGANQQDVEEHAKKTSEKRNLEVSKIQGPQPYVVTHKLMQRNFTSVRGELDTLMYNQDQIQNEVTQMSDLVRRLIDRLDQHVPASQYDQEFSLMESNFYSPSPTMSSLTAASVISSSIESRHMMRDRSCSELVPNTLSRPRMPMAESQKKHFGSQYRRRTSGSTHGAVINPGSSLPTSAQKAQPPPTFASPESSNAGATATLTCEADEVKKTGKVTKPAASNGSSWFHRVVSKTEATAYDATGAVRDDTGAVGDTAGVAKSPASGATGAVVHGAESAARGVGHISEVVAIGTGAVVVGGGLLAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MX88</accession>
    <name>A0A9P6MX88_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">mannose-1-phosphate guanylyltransferase</fullName>
            <ecNumber evidence="3">2.7.7.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">MPG1</name>
        <name evidence="11" type="ORF">BGZ80_009419</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>alpha-D-mannose 1-phosphate + GTP + H(+) = GDP-alpha-D-mannose + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:15229"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
            <dbReference type="EC" id="2.7.7.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Nucleotide-sugar biosynthesis; GDP-alpha-D-mannose biosynthesis; GDP-alpha-D-mannose from alpha-D-mannose 1-phosphate (GTP route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.13" evidence="3"/>
    <dbReference type="EMBL" id="JAAAID010000562">
        <property type="protein sequence ID" value="KAG0016129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MX88"/>
    <dbReference type="OrthoDB" id="1733332at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004475">
        <property type="term" value="F:mannose-1-phosphate guanylyltransferase (GTP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009298">
        <property type="term" value="P:GDP-mannose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06425">
        <property type="entry name" value="M1P_guanylylT_B_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000013">
        <property type="entry name" value="mannose-1-phosphate guanyltransferase beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056729">
        <property type="entry name" value="GMPPB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045233">
        <property type="entry name" value="GMPPB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050486">
        <property type="entry name" value="Mannose-1P_guanyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22572">
        <property type="entry name" value="SUGAR-1-PHOSPHATE GUANYL TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25087">
        <property type="entry name" value="GMPPB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="Trimeric LpxA-like enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Nucleotidyl transferase" evidence="9">
        <location>
            <begin position="2"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="Mannose-1-phosphate guanyltransferase C-terminal" evidence="10">
        <location>
            <begin position="255"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF25087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0016129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="363" mass="39592" checksum="8818B4023BDD3A54" modified="2023-09-13" version="1">MKALILVGGFGTRLRPLTLTLPKPLVEFANKPMILHQIEALAEAGVTDIVLAVNYRPEVMVDILQKYEDTYNVKITFSVETEPLGTAGPLALARDILGKDDSPFFVLNSDVICDFPFQKLKAFHAAHGNEGTIVVTKVEEPSKYGVIVNKPDSSVIDRFVEKPVEFVGNKINAGIYIFNPAILDRIELKPTSIEQETFPLMAADSQLHSFTLEGFWMDVGQPKDFLTGTCLYLSNISKINPGSLAHPDCGYVHGGNVLVDPTAKIGKDCRIGPNVVIGPGVVIGDGVRLQRCVLLQGSSVKDFAWVKNSIIGWHSTIGRWARIEGTSVLGDYVTVKDEVYINGGSILPNKSISSNITEPQIVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MX92</accession>
    <name>A0A9P6MX92_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_009507</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000577">
        <property type="protein sequence ID" value="KAG0015987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MX92"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0015987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="92" mass="10384" checksum="53E925395056F17B" modified="2023-09-13" version="1" fragment="single">QPEGWMSTEALVKGFLAPNKDILNASELGSLAVNHGGKTHVSIIETKAMLNLFKRRERKTLLIVDEHGMLFQRKPFAPNKFKFLSDLSDFGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXC0</accession>
    <name>A0A9P6MXC0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_009359</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000552">
        <property type="protein sequence ID" value="KAG0016221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXC0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025332">
        <property type="entry name" value="DUF4238"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14022">
        <property type="entry name" value="DUF4238"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0016221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="335" mass="39359" checksum="8FEA8ECA27AFDCE9" modified="2023-09-13" version="1">MRNQEITQADVGRSYGIQNMYRDLDSNDCMEFEKLLSKSESSAATFVQMIVSGSKDISLTRAKLLELKKFLFIMMYRCESRRNQYFLEIFDIITRRSIEKHMRFNNIHNIHEVWFENLKWIIKTPFDGIMDEIKRASPNGNIFAGSPLDIVSSYNGPIHIVELLDFNLLIMHYVCIWQAPEGSEFILTDNCFGCYEGPMGITLHFIYYAVVLANRSFMSSVPYDEITEMSLFKDHGLHVDPSCVYVKKCPRSHEDYTPEDVFKYRRIVIPKQKVWLVNGVFLDAAHKSVTYKSDASMYRSLLFYDKNKKKVRWIGRDYSRLKRKLFAEMNRTHSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXV8</accession>
    <name>A0A9P6MXV8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Aminotransferase class I/classII large domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_007867</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000411">
        <property type="protein sequence ID" value="KAG0017830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXV8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050478">
        <property type="entry name" value="Ethylene_sulfur-biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43795:SF39">
        <property type="entry name" value="AMINOTRANSFERASE CLASS I_CLASSII DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43795">
        <property type="entry name" value="BIFUNCTIONAL ASPARTATE AMINOTRANSFERASE AND GLUTAMATE/ASPARTATE-PREPHENATE AMINOTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="2">
        <location>
            <begin position="26"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0017830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="190" mass="20601" checksum="36081D48C8CFCDF8" modified="2023-09-13" version="1" fragment="single">MVVKSTLSLRAQDNLQGSNVMLDGVIKVNSNKFDAKSNPSGIINLGVAENQLMTKELAEILFGYGESPSGSKILRKHFANNIFNRYFNPHEPVHGEHIVLAAGCSAIVDNFTFSVCDPGDGILITTPYYGGFNTDIMVKSKCKVIPAHLGEISAFGVEQIEVMQQAVDKATHEGTRVRAFVISNPHNPLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MY40</accession>
    <name>A0A9P6MY40_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_008233</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000440">
        <property type="protein sequence ID" value="KAG0017485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MY40"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019419">
        <property type="entry name" value="AIM19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28177">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 19, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28177:SF1">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 19, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10315">
        <property type="entry name" value="Aim19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0017485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="155" mass="16360" checksum="B1EEB81A8F33C9E7" modified="2023-09-13" version="1">MSSAPVQAPEAGGPPSSVELYRRSTLHKLATSPFPDWTLAAIAAACLPTSARATPSPSGVVAQTASTAAVVTTGLPRLGVMMVFTGMWTFAGYMKYMKDPDNGTGTTTAWCLLYAFLNARRTFTQPRPLPSLLMAGVLANIAISGRKQLDVHFGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYQ1</accession>
    <name>A0A9P6MYQ1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 14">Lysophospholipase NTE1</fullName>
            <ecNumber evidence="3 14">3.1.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Intracellular phospholipase B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="primary">NTE1</name>
        <name evidence="18" type="ORF">BGZ80_008444</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Intracellular phospholipase B that catalyzes the double deacylation of phosphatidylcholine (PC) to glycerophosphocholine (GroPCho). Plays an important role in membrane lipid homeostasis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>a 1-acyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15177"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16870"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
            <dbReference type="ChEBI" id="CHEBI:58168"/>
            <dbReference type="EC" id="3.1.1.5"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the NTE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.5" evidence="3 14"/>
    <dbReference type="EMBL" id="JAAAID010000458">
        <property type="protein sequence ID" value="KAG0017282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004622">
        <property type="term" value="F:phosphatidylcholine lysophospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="term" value="P:phosphatidylcholine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="3"/>
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        <property type="entry name" value="Lysophospholipase NTE1"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="2"/>
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        <property type="entry name" value="Jelly Rolls"/>
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        <property type="entry name" value="NEUROPATHY TARGET ESTERASE SWS"/>
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        <property type="entry name" value="NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER"/>
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        <property type="entry name" value="cNMP_binding"/>
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        <property type="entry name" value="NTE_Ploop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
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    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="2"/>
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    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="3"/>
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        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="3"/>
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        <property type="match status" value="1"/>
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    <dbReference type="PROSITE" id="PS01237">
        <property type="entry name" value="UPF0028"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 14" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 13 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 13 14" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="11 13 14" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12 14" id="KW-0472">Membrane</keyword>
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    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
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            <begin position="93"/>
            <end position="112"/>
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    <feature type="transmembrane region" description="Helical" evidence="14">
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            <begin position="124"/>
            <end position="144"/>
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    <feature type="domain" description="Cyclic nucleotide-binding" evidence="16">
        <location>
            <begin position="201"/>
            <end position="256"/>
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    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="16">
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            <end position="756"/>
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    <feature type="domain" description="Cyclic nucleotide-binding" evidence="16">
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            <begin position="544"/>
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            <begin position="652"/>
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    <feature type="short sequence motif" description="GXGXXG" evidence="13">
        <location>
            <begin position="1220"/>
            <end position="1225"/>
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    <feature type="short sequence motif" description="GXSXG" evidence="13">
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            <begin position="1247"/>
            <end position="1251"/>
        </location>
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    <feature type="short sequence motif" description="DGA/G" evidence="13">
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            <begin position="1367"/>
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    <feature type="active site" description="Nucleophile" evidence="13">
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            <position position="1249"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="13">
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        </location>
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            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
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    </evidence>
    <evidence type="ECO:0000256" key="14">
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            <dbReference type="RuleBase" id="RU362043"/>
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    <evidence type="ECO:0000256" key="15">
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            <dbReference type="SAM" id="MobiDB-lite"/>
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    <evidence type="ECO:0000259" key="16">
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    <sequence length="1520" mass="168265" checksum="22788C81A0346A00" modified="2023-09-13" version="1">MDSTPENPLFGALGDIVPDTLLSTATHSVLAKATAATATAAAVAAAITNNFHTDHASNQIHGYSADSPHLHNAFAADTVEHTPFGTIPFLRSLFSFSFSVLGFMTMTLPTAVYRLLSWSFTLRLTFTTLLIASVLVCIVTWAVFRYRVLTKYSRLPKTDPGKHGSSFDLHPDNPFKSPQEEKESMTYPDEFLSAFLSSIKIFGYLEQPVFHELARHLQTRRLPAGDTILQHPDLERSFYIVVDGCVQVFEQVDKDEVDDHGVEDMSDPWNDPDHDYQLLNEVKNGGTLSSLFTILSLFTENVKLRHEDEPLKEFKRSDSRSKSNDDSTSPVESDQHRKSESTSPAHSPPTSSSGKWKHSPAHGSGLRTKSNIHTPTSPLSNPDHMAVFDDSAETTEFSFEDTDNAPTQPSAEEFDAMEDQDLQHYKTPNTKRRIIVARAMVDTTLAVIPAEAFHRLTQKFPQAAAHIVQVILIRFQRVTLLTGHKYLGLTKELLRMERSINEIGSYGLPPNFFRPKTMEYLKSKFSTVREESDDDEQPLAIRMKGSKKLGNPMKGKRPGMGRSKNSSSNALSPKIESTDHIRHGSGFSALLDDHSEEEDSYLRDQVMECLSRSIGLVQTPPPPKSNNSLRSELKPTGSSEYFSAMFQASLTGGNGPGGYPMKKTTSSNTNSDSTSLGVDDFNTSNSSSTVPSVMSEMENDVEIIYFPAGANLVEEGERNAGLFFVIDGILDVSISPKQDFKQPTSNMNEAPRNMFGHHLSSLDLKTNIPSPLSTKSSAHKRSASIHTKSPHALFSIQAGGLAGYLSALSGYPSFVTITARTNAYVGYLSKAALDRVMERNPTVLLTLAKRLITLVSPIVLHLDYAMEWMQVSASQVLHRQGDDCDSIYIVLNGRLRTIIESEPGKIEILNEFSQGESVGEMEVLMGTPFASTLHAIRDTEVARMPKTLFNALAHRHPEITIRISRLIAQRASDAMDSGPNSKARGVTPDSAINNSNLRTVGIIPVSSNVPVNEFAERLRNAMIGIGSTCTLLNQSTVMNILGKHAFSKIGKLKLDNWLNEQEEMSQIVLYLADGGLTSPWTQTCIRQSDCILLVGLGDEDPAVGDYERLLISMKSTARKELVLLHANRHCAPGSTAAWLKSRVWVHAHHHVQMPFKGPTMLSDTSRKKTIMNLKDHLEKFYTNIRSNNSQKSPAFHGNRSDFARLARRLTGRTVGLVLGGGGARGIAHIGIIKALEEAGIPIDIVGGTSMGAFIGGLYARESDNVAIFGRAKMFAGRMAAKWRMVADFTYPVTSWTTGHAFNRGIWKCFSDTQIQDFWLSYYCNTTNITFSRMEMHQAGYAWRYIRASMSLSGFLPPLCDNGHMLVDGGYMDNLPVQFMKSLGAQTIFAVDVGSDDDTTLHNYGDSLSGWLVLLNRWNPFSNVYRNIPNLADLQSRLAYVSSVKQLEAAKATPGSFYLKPPVQDYGTLEFSRFLEICEVGYEYGKEILEKWKKEGKLSHLLSASETAKSIRAKRVRRNSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZA4</accession>
    <name>A0A9P6MZA4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007189</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000364">
        <property type="protein sequence ID" value="KAG0018417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34491">
        <property type="entry name" value="A-TYPE INCLUSION PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34491:SF74">
        <property type="entry name" value="DUF4456 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="448"/>
            <end position="698"/>
        </location>
    </feature>
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            <begin position="507"/>
            <end position="537"/>
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            <begin position="538"/>
            <end position="550"/>
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            <begin position="595"/>
            <end position="619"/>
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            <begin position="1139"/>
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            <begin position="1175"/>
            <end position="1188"/>
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            <begin position="1219"/>
            <end position="1254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0018417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1307" mass="138499" checksum="A177BBD79FA1788C" modified="2023-09-13" version="1">MQQPPPHHFQALTPLQQQQLQQQQQQQQKFQQQQQQQQLLLMQQQQQQMQLKQFQQQQQLMQQRAALKNQTPLQQQHFQQQQYQLHQMQQQQQQQLLQQQQLQQQQLHQQMMSRPPIMQPQLQLPQQQTLPPSIPMQMQQTPISGPHPMQTNLILQQQQQQQQRMLAQMQQQQQQHLHMAHAGKPRPNGMPGMPGMPGMPPVPGMPGMAGMPGMQGMQGMQGMQGMQGMPGMPGAPTSSVMPGMPGMQGIQTMQTMPGISGMPNMPGVPAMPGMPGVPGVQGIPNVSGVSTVPGVSGVQGMPGMPAMPGVQASPGVTVRPPAVPNGTPAPSAPTKEYDVDIDKQVVQALLELNRELICVCIDYQNCGLNNDPDFLKYQTRLQSMLSYLATWTEISKILPLSKEPPPKPDLSPLPPARFPSATRAMVALPKVAVAFAAAQKVIIEKQEEEKKAAESTTKPEVAATSPPSNTKTAAPVPIATPSTTPSTTANGTTSNPAGPSSTPVVPAATINTTGIAGAAGSPMSPASQAAPAVASQPAAPPSQRPAPNAPPQQQWIQQQQWLQQNAQQSPQPQPGQAQLSLASSSLPTSIPPTNPSTMSLLHTTPQSAASSAPSLQSPTVVPTGQFQGPTMNASVDNSISAAPSVSSAPTTQNVDSPTSLVSASSTPTPLVISTPNGASNTGMMQAGPGSAQSSPALGGFALLKQGGSAVNSPAMAQAQAQSQPHTPASPMTGAPNVGSPAPQPLQQQVQSLQQQNSGSRNNSPLVSHQMLPMQRAGTVSATSSPSVSHAAIPPSGLQDPSGGQRLASPAPSSASIQHGSPSVPVPFVSQFQAHALSPTTAQPRPPMVPGPMGQGLQQPQQFPQQNMPMGMGMPMGMGVNMSQPMGIPMNVGFNHMGQPMQMTMPMQMPMQMAGGMQLPVGGKPMMGMGPGGVQMQLGPHQQHQMSQLQLHMMQQQHQFQQQQQQAQQQQQQQQQAQQAQQAQQAQQVQQQQQQQQQWHNQQQLLQQQQQQQQQQQQQQQQQQRPQSRQDSPLMSPGRGSPAMFSPTPMMNQQSQSRGPSRAGSMDLSSGTNLMSNGSQQGSPAPAPRLGLQTLPGSGPGSLDFSQQQLQSPQGGPGTSVSGISFGSNTNSNQSSMLGTPTLGNSNTNTSNSVQNTPTPNFGGSGGFNNSNNNNNGGGSSGTNVGGASTGLDDTSSYIADEGSDMLNLDMGLEMDEMDMSMGMGHNGSSNDDIYDSSNNVNSSNNNNNSGSGNNNVGGSGGYNNNDQDQDHHHHLQQQEQQGGLEGLEMDSMVNEDEDDVMSGFLNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZN3</accession>
    <name>A0A9P6MZN3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005283</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000261">
        <property type="protein sequence ID" value="KAG0019782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZN3"/>
    <dbReference type="OrthoDB" id="2447874at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040478600" evidence="1">
        <location>
            <begin position="22"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0019782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="252" mass="25161" checksum="4785E6943C134FBC" modified="2023-09-13" version="1">MTRIHFTPLLAAVALLALTTAAPSPSHLLSDQDLSALAPPDLSTLSAPIVAPVAAPIAPVAAPVASASPQVIPPQDISVGSETGVFPVTGVYPSLIYRPAIQLYDPLVSFQSGDDGSSDYGVYGGYGGYGFGGYSYDASPYIANGPAGVINRRQVPTGPSGQPSGVVGSSSDVATNTVIQPIVRIQPHALQPVPVPSLGIRDVMIANMASTGAVIATGGEIATGEISAVVGTTAAATATAIGSAKDRFGGVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0Q2</accession>
    <name>A0A9P6N0Q2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_003339</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000188">
        <property type="protein sequence ID" value="KAG0020923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0Q2"/>
    <dbReference type="OrthoDB" id="3044029at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040108747" evidence="2">
        <location>
            <begin position="21"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="229"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="194"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0020923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="280" mass="28592" checksum="597E500A1EC9ED16" modified="2023-09-13" version="1">MRATTLLLASAAVLAMGAQAQINGQIAALDSADSYCFFLPPMLGGDIAANEDKAIAFCNKANSRAPGAKIFPSGFVLSAHWATGNNWVQITGQIDPVQYALNPCDTGGQYDIKAPVGATCAGYKHFVNVIEPEIGVYGMRCCQEKADCDVTHSTYGVKRIYGDYDFSGPRADGPLPLSLKCVNGSLPAGVEVPTPSSGGSNTTSTASTTSTTSTVASTKTLTTVANTTSTISSAAPQKTTESAGSEAGTDNKVSQNAASGKDVMMAATAILAAAVGLIMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N132</accession>
    <name>A0A9P6N132_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004448</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000227">
        <property type="protein sequence ID" value="KAG0020286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N132"/>
    <dbReference type="OrthoDB" id="1259151at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031490">
        <property type="term" value="F:chromatin DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13214">
        <property type="entry name" value="PH-GRAM_WBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044852">
        <property type="entry name" value="WBP2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31606">
        <property type="entry name" value="WW DOMAIN BINDING PROTEIN 2, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31606:SF1">
        <property type="entry name" value="WW DOMAIN BINDING PROTEIN 2, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0020286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="220" mass="23483" checksum="59228CB3AC10F7F3" modified="2023-09-13" version="1">MSVNWVLVTTDGKDIVPLENETIFFREQGVRFELDCSNGGYPGAGASYASKDGTLLLTNQRVVYLCAEPTAFFSSASLPIGNIHDSKLVQPWFSAAFFKAVAMPVPRGGLTQPARLSITFSSKKMDGAAPQHLEQLPVYVPPSEPVPEPTATTDLTSTLDPSRTTSASTPLPEPSSTSNPVQSSVQPTAASTGPPPPQPLFQAQPHAIPSDLPPSYDQFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N165</accession>
    <name>A0A9P6N165_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">BRCA1 BRCA2-containing complex, subunit 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">BRCC3</name>
        <name evidence="3" type="ORF">BGZ80_002679</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000167">
        <property type="protein sequence ID" value="KAG0021310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N165"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040749">
        <property type="entry name" value="BRCC36_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050242">
        <property type="entry name" value="JAMM_MPN+_peptidase_M67A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10410">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18110">
        <property type="entry name" value="BRCC36_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102712">
        <property type="entry name" value="JAB1/MPN domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MPN" evidence="2">
        <location>
            <begin position="10"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="233"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0021310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="339" mass="37945" checksum="729B02CF80284C76" modified="2023-09-13" version="1">MSRSSSLSRVLVQSNVLHILLAHALSTEKEEIMGMLMGDWIKEGATEIARVDGVSLLTRSEKRKDRVEIGPEQLTMAAIEAEEITKATGKTTRVIGWYHSHPHITVFPSHVDLRTQLSQQLMDERFIGMIVSCFNTDSELSNKIQVTCFQSRPSDGAACQHIKLPFSVLNENPLESLTLPKLLEIPERIFDEQRQSFYKSIPMTAASSLPTKSSAKSGRENSKSPFLARAFSFSSTSSQKDREGDTIMSPISDGELEEQIIGKSRSDRGSMDDIPSEELSTKYIQKTMSIPDRMTFIRNSGVYVQSLSSLVDNLVGPTLQMLVDREQYNQSLVKMHPWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1A0</accession>
    <name>A0A9P6N1A0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_004893</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000245">
        <property type="protein sequence ID" value="KAG0020021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1A0"/>
    <dbReference type="OrthoDB" id="655030at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050562">
        <property type="entry name" value="FAD_mOase_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356:SF2">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356">
        <property type="entry name" value="FAD-DEPENDENT MONOOXYGENASE ASQG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="6"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="413"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="249"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="612"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="249"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="288"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="319"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="330"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0020021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="634" mass="69808" checksum="5103CBE086C00878" modified="2023-09-13" version="1">MAPQQFKVLIVGGGIVGLSLGVMLDRAGIDFLILEAWKEDRPLGAVVHLGAPVLRAFEQLGLLEDVTRQSNRMGGVTLWDHKLNKICHISTEHAKDRYGYDTLTIIRPKLHDILLARIPAYKIFFGKRVVSMAQNGDGAKVRCEDGSTYSGDIIVAADGGASPIRKAIYEEIKNRSKKAPHPSDYAPPKLDQRCISGITEPLSVKQYPVLASKSHEVMMVMPKESNCMIWMAPVGPERRFGWGITSSLPSVDTSSSTDTKLSTFNTRGSLESGFTIPGSPSVGNTQRTFSTISSTSYSPPSSPNPTAFSEGRDYITYNGLGSHQSPSNALRKRQSTSRLSKHSSSSSGSQKTFQQYPAVLQMSESTTLDLRDLPNDRVWGKLDERYTIEDSIREQATPYGGTLGDLIDATSKKMISSVVVEEKFYHTWHFGRTILVGDACHKFLPSSGHSTTQGILDAISLASLLTELPSNSITDVDALFRVQYERRGPIAKAAVISSKQQDQVLFNRKLSGKIVRKIASTWLSDWAIIKMSDRIFETRPILPFLKPVPDRGSHKYKDNTVPLTKDKRFELARRKSIASGYLTGGTGSYKLGEKDSDDTKDLDFEIEVSLFSTSTPSINGPPPPVPSLTRPRHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1U9</accession>
    <name>A0A9P6N1U9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Nudix hydrolase 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_002366</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000158">
        <property type="protein sequence ID" value="KAG0021449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1U9"/>
    <dbReference type="OrthoDB" id="510307at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.540.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039461">
        <property type="entry name" value="Peptidase_M49"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23422">
        <property type="entry name" value="DIPEPTIDYL PEPTIDASE III-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23422:SF9">
        <property type="entry name" value="ZN-DEPENDENT HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03571">
        <property type="entry name" value="Peptidase_M49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0021449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="553" mass="62187" checksum="4FA47F3A64809968" modified="2023-09-13" version="1">MATAASTPLEKQLARFQEIQVGGSKYLGRISAGDREAIPLLIQVGKLIDQIFIRQYWSSNEALHTHILNQTPRDTKLELGLQLFKGPWGLDEERFIDSIKEHNHNGDVHKAIHIPHEPPRHANYYPDDIDKQEYLDWVSGLEGQEKINAESYYYVIKRDAATGKLYSVPYSEEYKEFLIPASQLLKQAADLVSDKSLSKFLKSRAEAFISNDYVDSDVDWLRISKESPLDVTCGPYENYADKLFSIRAAYEFYLHARDFESSDILAKFSSRLQDMEDQLPVGELYKAKGLQPPAIVTVNQLYSGGDVAVPMTAAYNLPNDEAPIKIAGSKLVIIKNVQEGKFEKVLRPIAQQVLEPEQLEKVEFEAFFQHVLMHEVAHSLGPHFLVRDKETKVRSALQEYHSAMEEAKADIAGLYAVGLLLKDGTLAGGPNAESFYITFLASAFRSIRFGITEAHGLGQAIQFQYLREQGAFAYDPETNKFSVVMDKIEDAVKSLTARILILQGDGDKGKVKEFVDKYGIISPEVKQALSNLENLGVPVDVYPKYRILEDGTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1Y2</accession>
    <name>A0A9P6N1Y2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Eukaryotic translation initiation factor 2C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">EIF2C4_1</name>
        <name evidence="3" type="ORF">BGZ80_003869</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000205">
        <property type="protein sequence ID" value="KAG0020643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1Y2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02846">
        <property type="entry name" value="PAZ_argonaute_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04657">
        <property type="entry name" value="Piwi_ago-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.260.10">
        <property type="entry name" value="paz domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014811">
        <property type="entry name" value="ArgoL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032472">
        <property type="entry name" value="ArgoL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032473">
        <property type="entry name" value="Argonaute_Mid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032474">
        <property type="entry name" value="Argonaute_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003100">
        <property type="entry name" value="PAZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036085">
        <property type="entry name" value="PAZ_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003165">
        <property type="entry name" value="Piwi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045246">
        <property type="entry name" value="Piwi_ago-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22891">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08699">
        <property type="entry name" value="ArgoL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16488">
        <property type="entry name" value="ArgoL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16487">
        <property type="entry name" value="ArgoMid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16486">
        <property type="entry name" value="ArgoN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02170">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02171">
        <property type="entry name" value="Piwi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01163">
        <property type="entry name" value="DUF1785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00950">
        <property type="entry name" value="Piwi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101690">
        <property type="entry name" value="PAZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50821">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50822">
        <property type="entry name" value="PIWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAZ" evidence="1">
        <location>
            <begin position="231"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="domain" description="Piwi" evidence="2">
        <location>
            <begin position="528"/>
            <end position="829"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0020643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="865" mass="96824" checksum="7DD56339B3607AEB" modified="2023-09-13" version="1">MSQLQLTDFVKRPGQGKSGREIQVRTNFFEITQLPNITIHHYDLTVTPDVPPPVNRRIFEALMNHYRDTDLEGAQPVFDGRKSLFSPKKFSFDSRVLDCRNDDNTNFHVSYNKVILPGDVNNKRSPIPVFKVKIKKAAVINLEELHRFLQGKCAMTNNCLTAIMSLDVLIRHKPAMAHVTIGRAFYTSAARQALSGPLEAWRGYYQSVRPACDKMMINIDTTATAFFQSGPLIEIVVKILGLRTPEDLRRTVPPVNWLRVEKAIKGLCIQVSHRQRAKKTLKIFGMTKTAARDTLFKLNVDPKDGSAPSQQREIDIVNYFKETYNITLSYPSLPCVTVGKTAILPLEVCTVIEGQRYMKKLDERQTADMIKFTSQPPAARANNIKDGVKLLNYEDNEFIKDFGMKISNEMATIRARILQAPTISYHGSSREANFVPRNGSWNLRDKKVAMGAVLGSWGVIVFGSEREAPESQIRNFIRELGISFVETGMNVANKSPPFMYANPQGNIESSLKNAWIQAGNAVKSQPQLLVCILFNTGTPLYAEIKRVTDTILGVSSQCIQVKHTREPKKQYCANVCLKVNVKLGGMNSYLAQGMIPFCTTKPSILIGGDVSHPQPGDTTRPSIAALVGSMDSKASRYAATIRVQTARTETIADLGDMMIDLLRTFYQTCGEKPTRILFYRDGVSEGQFAEVLKNEIAAIRAACQRLDINYKPDLTFVVVQKRHHTRFFPLKPSEGNQLGNCHPGTVIDTHIVHPFEFDFYLQSHAGLIGTSRPAHYYVLLDDNKFAPDELQELTYKLCHLYARCTRSVSIVPAAYYAHLVAARARFHARGDHFSDTVSSNSAGGAGEASSYASVKPDLMKVMWFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2C0</accession>
    <name>A0A9P6N2C0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Zinc finger C3H1 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">ZFC3H1</name>
        <name evidence="13" type="ORF">BGZ80_002807</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Centromere</location>
            <location evidence="2">Kinetochore</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000171">
        <property type="protein sequence ID" value="KAG0021239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000178">
        <property type="term" value="C:exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000444">
        <property type="term" value="C:MIS12/MIND type complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007128">
        <property type="entry name" value="PMF1/Nnf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019607">
        <property type="entry name" value="Putative_zinc-finger_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039278">
        <property type="entry name" value="Red1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21563">
        <property type="entry name" value="ZINC FINGER C3H1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21563:SF3">
        <property type="entry name" value="ZINC FINGER C3H1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03980">
        <property type="entry name" value="Nnf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10650">
        <property type="entry name" value="zf-C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="9" id="KW-0137">Centromere</keyword>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="5" id="KW-0498">Mitosis</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Putative zinc-finger" evidence="12">
        <location>
            <begin position="1707"/>
            <end position="1726"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="218"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="301"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="415"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="454"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="775"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="845"/>
            <end position="1017"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1033"/>
            <end position="1144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1177"/>
            <end position="1211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1228"/>
            <end position="1286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1441"/>
            <end position="1490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1524"/>
            <end position="1549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1587"/>
            <end position="1606"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1804"/>
            <end position="1827"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="2449"/>
            <end position="2486"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="1293"/>
            <end position="1327"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="1355"/>
            <end position="1403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="218"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="301"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="338"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="354"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="415"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="464"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="543"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="845"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="866"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="907"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="926"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="937"/>
            <end position="971"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="980"/>
            <end position="1011"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1033"/>
            <end position="1049"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="1050"/>
            <end position="1063"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1114"/>
            <end position="1127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1188"/>
            <end position="1211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1235"/>
            <end position="1258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1259"/>
            <end position="1271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1441"/>
            <end position="1462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1524"/>
            <end position="1537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1594"/>
            <end position="1603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="2449"/>
            <end position="2465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF10650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0021239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="2486" mass="274751" checksum="88C677391F8D8FDC" modified="2023-09-13" version="1">MVATGTAFPNQTGEEELMDIVHGQDVEEQEEPEGPRMTRLRGILDKSLKETLKACNYAAICECFPALAAANPRDLREAHEKVCQFLNIEVNNEFEQIIKERNVIFKLNGLDRLIADARGKGNTAGSRTILDLSPEVAVRARTVPTKEAEIERLKAELERVQLDNRRIGGALNHSKAEQAAIKLELLESYNEFQEDTMSKTPAELDALRAAVLMTRRQPAQTTQIASNVEQSAPETSSERSTMPVIDSSINLGPSVIFAPVSTETSNLNTYPTPLSTALTGKASPSTLGSLTVATSATAHVPTTYNTTNKPSNGAVAPPKTHSSQPTDREDGEISDEELGVKPETETEHDLESAASRSRVSDTRSNQPTGLTIEAQTGAIPAPLPLHGRPQLPSHQALMERVPRYTQRLLGTIRPSITTNTATSKGKSKSLDIGGIKLGQDPDFNSLIEEYQLQKAKSDSKSHPAATNQDQTLDSEIPGLGHLKTLSPDFSLSDRNFRRQPNIGRRPGDQVRQLAPRNQRGDRVTKRRSRDMSLNIKQQPTPPVHHEMQRHRSDPNPGFVTLSPQTANGQINDFTQVPPTHQASSQGQIYSLVEELLSYGVTPEYLLQSGIDPAVVYHVSSTRTPLASPIVPVGPTQGFHLNPQALAVASMQLATQYPQPSASAPISQPFIPQFGQVHQQPHLTGYSMRDTSMDVSQPQSIQQQHTQVQQTPQTIPQQLCTPTPTAIVSEDDASRKLEMILAYAAKILPQGWHSLVPQGGTDTNVTPVNVESLESARGLDPASTPYQDNAHEKAPESLRAVKVEQDGDRWAPLKQNLSQENGQIARPGWNLSEEARFTTAKFQDLSISPNQQMQNQQTTISSTTSSGAHISVQSIDTSPSLKQHNTEELRPINNDSMSTKIAPPSVLYERKYPRDNGQSHDTGPSISTASTNTSRSPSRPPPPPPPAHPPPSPPPPPTSAPPSPPTSTPPTYSPHLELGTGATSESLSSKANLESNRSNVLDNTMPSNLNNIDHSRSDNDESINLFYLDSVPKEQNSTEVGSQRGSSASLDDTDMDIDIDDDSTEPTILKGSWKTTEDIPPTTPASSTQPVPKRPTHIRFDRMGNTLPSPVHSASMLTTSTQADNQDANGHFLPTVSRPQRNGRRVTAKDFMLKPLSSTPFIQERALSYLIDIDDEDDDEYEPRVDTPTAKSSTPISRADSINSPQESRTLQDIQQQLKELNERILAKQRAKRSALSASATDGSTPKNTPTGLTSRSETGSPAQPSGSSSNSEDQMMEKVSDTNSIGQEAYVKAEELRRTINEHKASLEGLRSQKQQYEQDRTEAMNLLADALSSNANNQDYGKLQRSIDEAAEKVAIKMREFEDAKRHLEEIKARTGPILSQQSDLQKTKERLQGRIDLANEKTAGLKSSIGSLQQNIIQMRTQLMILEGKYAPKLDATNSEACLPSTPNTNSTTQDINSDTVPKRGIDPQGQTPPMNAKKPRTQAREEFSALSKRMQELEREKDLLRSASAPSTVTNGISTVSIQQPGKTNTTQLPSLYPSPHGSVPSHSKVNLGVPAGDGNVAPAVTSKTLSRLDEFLAQDKSLPITPVADNDNQSPSPSGRPTAGIKKLYLAESCLFELDQLCMPSELIKYVIPDRQNGSQVDSSAVLYKPSASDSKSSKDALDYVSPLSMFRSFRFSPRFRDAVRDGYKSLTYSNKIDPMKPMCLYELSGGSCNDDSCKSQHARDYELTDEELVIDMARYAEGNTPESRQVFAEMQSAKLAHLRAAGIHNVELLVDSIVKNHRDFVQDSSRTVKFGERIVTDNDATDSPATRNKPKGHSGSRAVDRLVESSKASFNSLDQSPISMVILSKALTGSLAKNRRYHEQRHPDNFEKQVLADPSNETLWIEYAISHLSTMSVDETNGAGDHSIHNALSVLSRALGVHPSSENLWGLYLDLYTRHGAESETRQMFEQCLHYVPDAQLIWFRYFLWEKDRDERVYVLDRMLERACQEPRKADDEAARSRFTLDVVLQIVKTMVSENFVESAKNWMQNFLTCTAWESIVPSSLSYAQLDDVWIEQDMVENIAGTLAAKLLKPNDHCILWLAFVYLIWFHELPDQLFQDYPNGYISDNSLFVIHWPEIEEPEQESELHSIVHDIFLGLTVYFVDCDARSPLVATVKNFVGFLIARGQQQEEILELVNPSQFPESFPEIRDLFCQVRMPAESKQACLEQCAYEFFKVESSHEVGIGRSELALRLYRKLLGLSLPYSYEAPVARSDITSIRTNVFMWLNYLSLLALGSGSYSQLEAAFSSAMEALPADKISVIQTEFAIHSIMKELHKATNASAINSLVAMAISDINILRPNPYDHSVAELTKVLALRDFSQLNRIIEAVWNRTVECSRQLQVDLVDSFLRLHPENPDFYLWLITTFAGPGSQGSMDLILKASLFSPLAAKLSRMPTIHDVSKQLKSMETEERAHEEKALDNHNTLESQGFDSGSDMDMDDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2P7</accession>
    <name>A0A9P6N2P7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosome-releasing factor 2, mitochondrial</fullName>
            <shortName evidence="6">RRF2mt</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Elongation factor G 2, mitochondrial</fullName>
            <shortName evidence="6">EF-G2mt</shortName>
            <shortName evidence="6">mEF-G 2</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">MEF2_1</name>
        <name evidence="6" type="synonym">MEF2</name>
        <name evidence="9" type="ORF">BGZ80_001680</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.</text>
    </comment>
    <comment type="function">
        <text evidence="6">Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Not involved in the GTP-dependent ribosomal translocation step during translation elongation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000139">
        <property type="protein sequence ID" value="KAG0021801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N2P7"/>
    <dbReference type="OrthoDB" id="198619at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032790">
        <property type="term" value="P:ribosome disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01886">
        <property type="entry name" value="EF-G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16262">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03713">
        <property type="entry name" value="EFG_mtEFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.870:FF:000007">
        <property type="entry name" value="Ribosome-releasing factor 2, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000514">
        <property type="entry name" value="Ribosome-releasing factor 2, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.870">
        <property type="entry name" value="Elongation Factor G (Translational Gtpase), domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03059">
        <property type="entry name" value="mEF_G_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053905">
        <property type="entry name" value="EF-G-like_DII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030851">
        <property type="entry name" value="EFG2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009022">
        <property type="entry name" value="EFG_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035649">
        <property type="entry name" value="EFG_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005517">
        <property type="entry name" value="Transl_elong_EFG/EF2_IV"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43261:SF1">
        <property type="entry name" value="RIBOSOME-RELEASING FACTOR 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43261">
        <property type="entry name" value="TRANSLATION ELONGATION FACTOR G-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22042">
        <property type="entry name" value="EF-G_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03764">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="8">
        <location>
            <begin position="63"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="601"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="804"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="812"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="72"/>
            <end position="79"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="136"/>
            <end position="140"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="190"/>
            <end position="193"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0021801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="888" mass="96004" checksum="61052BB922F69EB0" modified="2023-09-13" version="1">MQLPPGSAFRSVLASGNGRPFSKWTACSRALVNTGRFKARTVVPLQSSQWYSSHAHKTDVAIKNCRNIGIIAHIDAGKTTTTERMLHYAGFTRRIGDVDSGDTIMDYMKQERERGITITSAAITFGWKDHRINLIDTPGHVDFTIEVERSIRVLDGAVTILDAVAGVEAQTETVWQQAARQGVPRIAFVNKMDRAGAGFGRTVREMRTRLGCRPVVIQIPLMESPTGASGSGANDAEFSGVVDVLSMEILRWDADSKGAKVIRSPLDPSYPDQELYQEAVKARVAVVEQISALDEKIIDLFLTLEDHMAIETKDLRAAIRRLTLSSTIVPVLCGASFKNIGVQPLMDSVVDFLPSPDERPAAIARMPDGKMVEIGSGGPKERLCALAFKVIHDARRGPMVFVRIYAGQLNERAQLWNSTTHAKERANKLLQMYAMDVEEITHITKGNIGVVLGLKDTRTGDTLIDAHDSRKGLALSGIKVPSPVFFAAIEPMSTSDEKPVEEAIKALIREDPSLGMRIDEETGQTLLGGMGELHLEVAKERLVSDFKVNAEMGKMRISFKETMRGAGIVSEVPNWEYDREILGKRGRARVGISVERLEQFEDTGDNTSASASKVENGKESKDSNLASEEYEGNEIVISLAEQPTKSDEAGAQSAAEKAASTGTVILSGSTDLPIPAIRNAVKNGILSALSRGPLLGYAQTYLKVRLTDLHLYGGDSTPAAISSCVSAAVTEAIRLGGNSSTKENDSNSVLLEPIMDVRVEVAEKDVGTVIGDISGTRRGRVLSLDGSSHEASHEADDLGEFNIYAPPDPTYTGPGASPSSPKSSSTGIATMADRKSIRAQVPLSSMLGYDAALRALTGGTGKFAMEVIGYGEMDFDRQRELIREMRGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N317</accession>
    <name>A0A9P6N317_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_001927</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000146">
        <property type="protein sequence ID" value="KAG0021668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N317"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051350">
        <property type="entry name" value="WD_repeat-ST_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22838">
        <property type="entry name" value="WD REPEAT PROTEIN 26-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22838:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="234"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0021668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="328" mass="37040" checksum="73A4B9B1128D5A47" modified="2023-09-13" version="1">MGRKHLHFSRLKHALLIQHLQCPDPSIHFSTNLSRTITAVAWSPDSKYLLINLGYDKKNPCYTPTVKLIDVQSGEIVFKKHYMKNGDNFHANAVCWFPDSKRFLTAVEGVYCIWDLNGNVIREYPVNNELTGLHLTAIPGTEKFIINTFDTIEIISFDDTVSTKLLDRNICTKFSMTVSNDGAYLAVTLRGEKCVDRPAQIALYDLKSMTFLRFFEAETYIDEAFVIVPTFVGPNMELLCAGSENGKLHYWDIETGELVSVLEEHSLHVGGVSANPGHPGMVASCSDDSLVIIWATKQLQRELKEDDDKWMREHPAVAMPTVNIKKGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N356</accession>
    <name>A0A9P6N356_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_009276</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SCC4/mau-2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000054">
        <property type="protein sequence ID" value="KAG0023501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N356"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007064">
        <property type="term" value="P:mitotic sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019440">
        <property type="entry name" value="MAU2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21394">
        <property type="entry name" value="MAU2 CHROMATID COHESION FACTOR HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10345">
        <property type="entry name" value="Cohesin_load"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="5" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="4" id="KW-0498">Mitosis</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="172"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="176"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0023501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="412" mass="46388" checksum="B337550F26844475" modified="2023-09-13" version="1">MTQLDKAKSGLRLAQILFEETESLERSEEEVNKAIIIADSIQGSSALDIQLRLYELQILIQMEMKKYRFAKNTLRIASSIAAKQELHWWTYQFYLLKARVFFLTNDFAGSLTTLNQGAALADQRGDFDLKMAFWIVAGQYSLMLSNWDQANIYLQKLMPHMGLDETLALSSSSTVTPPLKDPSSSSLDSPSTPPVPQQSVKQELCQTKQLRVFFLILYISCMLRSGAVAKALVALTALHSALDETRPKDTEELQGVFRIPLKVNQYNDMQHQPRHVPPQDTPCSYISIKWMSFSQVYCLTYLLSGICSKADMTQPMKCQQFLLEGIKVVDRNVYLQTHDDQAEKMLMAGYMHAAKTGNQVIAAATGSCLKDLYLATSQGIKASQQTKQNMPILETVDRVFQSRPMGPLLSQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3R5</accession>
    <name>A0A9P6N3R5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">50S ribosomal protein L9, chloroplastic</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_005881</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000029">
        <property type="protein sequence ID" value="KAG0024116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3R5"/>
    <dbReference type="OrthoDB" id="5555409at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.430.100">
        <property type="entry name" value="Ribosomal protein L9, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.5.10">
        <property type="entry name" value="Ribosomal protein L9, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000244">
        <property type="entry name" value="Ribosomal_bL9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009027">
        <property type="entry name" value="Ribosomal_bL9/RNase_H1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020069">
        <property type="entry name" value="Ribosomal_bL9_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036791">
        <property type="entry name" value="Ribosomal_bL9_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020070">
        <property type="entry name" value="Ribosomal_bL9_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036935">
        <property type="entry name" value="Ribosomal_bL9_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21368">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03948">
        <property type="entry name" value="Ribosomal_L9_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01281">
        <property type="entry name" value="Ribosomal_L9_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55658">
        <property type="entry name" value="L9 N-domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55653">
        <property type="entry name" value="Ribosomal protein L9 C-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal protein L9" evidence="7">
        <location>
            <begin position="3"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein bL9 C-terminal" evidence="8">
        <location>
            <begin position="101"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0024116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="164" mass="18351" checksum="93FD00D6F5E6DA78" modified="2023-09-13" version="1">MAEVRGLGKQGDVVSVAPGLMRNRLLPMRFARYIDRNARHIRAEAIAGQDALKSAQEVNKAYQQTIKREQRIVQLQELRHRLQVLPPLVFSRAVNEVLPGSKTIFGSVQAEDVVKELKEKHGIVVDHSKVTVNGTKIKSIGDSWARIDLGELGSVELKVVVERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3S4</accession>
    <name>A0A9P6N3S4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DDB1- and CUL4-associated factor 12 beta-propeller domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_010723</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000078">
        <property type="protein sequence ID" value="KAG0022957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3S4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056151">
        <property type="entry name" value="Beta-prop_DCAF12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23760">
        <property type="entry name" value="Beta-prop_DCAF12"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="DDB1- and CUL4-associated factor 12 beta-propeller" evidence="3">
        <location>
            <begin position="264"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="307"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="domain" description="DDB1- and CUL4-associated factor 12 beta-propeller" evidence="3">
        <location>
            <begin position="376"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="23"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="44"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0022957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="488" mass="52803" checksum="0CD0F95DB5E0045D" modified="2023-09-13" version="1" fragment="single">MAQELRDIRLFGTQPGGGDRRMSTSSIPITPKQSTQSRFEDSESSSSSSSSSSSTLCHNTSTTQPLSSSTPGESSGSDPIANYVSTRIPSIIREHEYSVVGYDKVFAATWITGEDVLFGTKCNKIVLLNTRTDKQVPIGRLDEHVLEDTNRALSRIEGMTSKIMASNSSQVSRGNSTTAYTHPLENTTVNYLSDNLSDLDFASRAMERNLRLFNPGRRSSTPSFPSTGNSGYGGVVAPAAAAAVSPSPVANTTTSPSGLFGIGMASVSTGIRSMSINPSRTLLAIGSGEPFQVTIYSLPGLEPVGIMYGHTDLVFGLTWISDTVLATGSRDGSMRIWSMGSPVITTLPTVSREIQVRLPSITRKEERTRVRDLAFNKRSEMFKFRLNHPMETVCLTSSVEANLFAVGSQSHISIVDPRASTIVHEAESCDEGCGVRSLDFKSHIITTGDGYGRIGFYDLRAQNYLDVSSVSDDDSKTRRYHEIGPGWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4A7</accession>
    <name>A0A9P6N4A7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Penicillin-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_000899</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000012">
        <property type="protein sequence ID" value="KAG0024598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N4A7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.600">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050491">
        <property type="entry name" value="AmpC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021860">
        <property type="entry name" value="Peptidase_S12_Pab87-rel_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46825:SF15">
        <property type="entry name" value="BETA-LACTAMASE-RELATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46825">
        <property type="entry name" value="D-ALANYL-D-ALANINE-CARBOXYPEPTIDASE/ENDOPEPTIDASE AMPH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11954">
        <property type="entry name" value="DUF3471"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase-related" evidence="2">
        <location>
            <begin position="11"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S12 Pab87-related C-terminal" evidence="3">
        <location>
            <begin position="382"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF11954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0024598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="477" mass="53604" checksum="1DE3F577F517B39A" modified="2023-09-13" version="1">MNEALETAKLSCGIPGMSVAILYKGEIIYAKGFGKRNESGDPFTKETVMPIASVTKAFTSTTIGELVAEGKMDWDKTPVSRYLPEFELQDPILTSRLTMADLLSHRTGFPDIDIAWFRNATPRRDLIKRMKHVKMETKLGSDALYNNVMYAVAGEAAANVAGVSYEKLVVDKVLDPLGLTNTGFGPMEMKQRQNYAMPYGAASLDDAKKGLYELGYLDEVYAADSPAGDMYSNVLDLVRWGRVIIKHGELDGKQVLNKQSVQETLNGYTFMNKKRRGPEFAPVQSYGLGWCLDSYKGQIIYRHNGSVPGYRSELALVPNSDLVIACLANIDAALLTNISYHVLDEILDLPKTQDWITSEFVKDTLRIYEDYANIAKGDLPERIENRPPAHGLGAYVGDYSHPVYGNISIRLEEELLFFKMRTFDNEMEHYHFDSFKAFLHDFATKLTILVNFQTGQDGKVEGFKVDFDHGPLEFRRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4B2</accession>
    <name>A0A9P6N4B2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Actin-like protein arp8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ARP8</name>
        <name evidence="3" type="ORF">BGZ80_009343</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000055">
        <property type="protein sequence ID" value="KAG0023476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N4B2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10206">
        <property type="entry name" value="ASKHA_NBD_Arp8-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="271"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="424"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="848"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="17"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="52"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="96"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="115"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="126"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="146"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="158"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="188"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="279"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="335"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="351"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="428"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="454"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="472"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="855"/>
            <end position="875"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0023476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1049" mass="114404" checksum="A07FA027592E877A" modified="2023-09-13" version="1">MEDVHMEDAGVAVEAGSTLNASSSSPSTHSQNLSPQQQDSKDAINANVDNAVVSQSGDQATTITSQTESDVSTPATASITTNSLTANDSNLHETKQSSAANESSTMDVDASMPVDEVKNEPKDIQQADNDNSGSSHSKALDTVTSEPKEQEREKVEVTATAESSATAQASLSSDQLQPNGIDGAKGNQLDNSTASTDAQAVKGQGEETQPTELSATATPAPQPQPQPQLLRSYIPQFKFTTFTAMTPLPTRNVTSNFLRTEKNFVLKEMATKRKRRKRKVEDNTNVEEGKGTEGEIEGEEKPKGDEGVVLKKAKNDEFSAIRRGIFAEDNDEEDKDRSDNEDGDDDQKREDDDEYEYSSESDSEASIVNETDENGETKSSSDAGKKIIVIHPGSRILRIGRASDAYPVATPHCIARRMHVKATVAANGKQSSVTTTAPGSSEDAATTATANGVETSTEASTEEALPSTVEGDNVDVEDENAMDVDGDDDAPDSEVPDIVNDRYLQEIEYDLKLRMKAAKRRPVPNAKTQVRSFNTSTRPERILDHNDPYKVEWTDPASEGEYIIGQKALNLPPSKNHSFKLFWPVLGGKLNDQDYTTPRVVVSDLETIWTKVIQEDLGIEPNKFRKHYALLVIPDLYNKLYVIELVNMLLRSMQFRGVMVQQESVCASFGAGVSAACVVDIGAEVTKVACVEDGICIPNSRAVLKYGGDDITRCFTALVKRTGFPYQELDLAQTYDWRLMEELKEKWCTMNEADLTVQVYNFFVRRPEKQTEKYQVKVYDEVALSPMCLFFPGVIRRWIEEREINPTFAKITNYEDINEDAPPISLTNQSQKKSSAAAAIAAAARAGTPSLMVPGEENNTNTNGNATPSVGTPGATPVPTPTPSAVPTTPAASAAILAPTVIPFAMEPSVTTTDKSWEIAGTIGKDHFSSLVALDVVVAQSISNCGSEERSKKLYGSIILVGGGGMIKGFDRVLEDRLFQALPATLTTVEKVEVLPSPRDMDPRLLVWKGASVLGKLETAKELWIKPLEWELMGRKILRDKALFVWSKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4C8</accession>
    <name>A0A9P6N4C8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Probable RNA polymerase II nuclear localization protein SLC7A6OS</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BGZ80_004534</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Directs RNA polymerase II nuclear import.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the IWR1/SLC7A6OS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000023">
        <property type="protein sequence ID" value="KAG0024294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N4C8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032502">
        <property type="term" value="P:developmental process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040218">
        <property type="entry name" value="SLC7A6OS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013883">
        <property type="entry name" value="TF_Iwr1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31196">
        <property type="entry name" value="RNA POLYMERASE II NUCLEAR LOCALIZATION PROTEIN SLC7A6OS-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31196:SF2">
        <property type="entry name" value="RNA POLYMERASE II NUCLEAR LOCALIZATION PROTEIN SLC7A6OS-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08574">
        <property type="entry name" value="Iwr1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Transcription factor Iwr1" evidence="11">
        <location>
            <begin position="390"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="137"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="195"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="354"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="428"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="8"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="27"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="137"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="147"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="195"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="359"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="428"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="469"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0024294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="478" mass="53966" checksum="FE6CBF667B8561D5" modified="2023-09-13" version="1">MSKTDFMTLHTNTSESTSSTPTLGLAATNSDIARQSPPHQQQSSIFLKKKKPTVASVGSKPLIRPFNNKFIDYNNPGKHDPIPLKPTKGTVILLPGSSPNAPEITNVFSLDANSSSSFSSVPFIFDNHTPESMTLNQTKTRAQQDNATSTSTGSPAAGGSTTSGPNNDAFTILRIKRKRYEEPLDTLVVQEQMEKLSGKKQKKIEDSIQQERDNTQAGQVSLPKPPPAVFRLATTVNKESFKDPTQSIQLRDKITHMAENRRPRSRMSERIQDLESFAQKNRAELTERMQKDARSSVEAEAEAALDVFKMYDAVREDEPKSEKQPSVTNAEESDIMCNFLPMVREYLSISEKTPEPRIINTSESGEGSTTPLPRTRRNFDDDSDFDDSEDEYVYDIYYRDLHADHQQESKHRAIGALLWFSDDENNFMNEDDSSDDDFEDSDSNAEDYYQNDYPEDELSDNDYNPYDLSDTDDDDYLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4T9</accession>
    <name>A0A9P6N4T9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 16">Pyruvate kinase</fullName>
            <ecNumber evidence="6 16">2.7.1.40</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">PYK1_4</name>
        <name evidence="19" type="ORF">BGZ80_008919</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15 16">
            <text>pyruvate + ATP = phosphoenolpyruvate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18157"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.40"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 16">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 5/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 16">Belongs to the pyruvate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.40" evidence="6 16"/>
    <dbReference type="EMBL" id="JAAAID010000050">
        <property type="protein sequence ID" value="KAG0023594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N4T9"/>
    <dbReference type="OrthoDB" id="108365at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030955">
        <property type="term" value="F:potassium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004743">
        <property type="term" value="F:pyruvate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00288">
        <property type="entry name" value="Pyruvate_Kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.33.10:FF:000001">
        <property type="entry name" value="Pyruvate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.60:FF:000001">
        <property type="entry name" value="Pyruvate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1380.20:FF:000001">
        <property type="entry name" value="Pyruvate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.33.10">
        <property type="entry name" value="PK beta-barrel domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1380.20">
        <property type="entry name" value="Pyruvate kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001697">
        <property type="entry name" value="Pyr_Knase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011037">
        <property type="entry name" value="Pyrv_Knase-like_insert_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018209">
        <property type="entry name" value="Pyrv_Knase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015793">
        <property type="entry name" value="Pyrv_Knase_brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015795">
        <property type="entry name" value="Pyrv_Knase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036918">
        <property type="entry name" value="Pyrv_Knase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015806">
        <property type="entry name" value="Pyrv_Knase_insert_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004491">
        <property type="entry name" value="PRK05826.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004978">
        <property type="entry name" value="PRK06354.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01064">
        <property type="entry name" value="pyruv_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11817">
        <property type="entry name" value="PYRUVATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00224">
        <property type="entry name" value="PK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02887">
        <property type="entry name" value="PK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01050">
        <property type="entry name" value="PYRUVTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50800">
        <property type="entry name" value="PK beta-barrel domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52935">
        <property type="entry name" value="PK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00110">
        <property type="entry name" value="PYRUVATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13 16" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="10 16 19" id="KW-0418">Kinase</keyword>
    <keyword evidence="12 16" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14 19" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 16" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyruvate kinase barrel" evidence="17">
        <location>
            <begin position="25"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="Pyruvate kinase C-terminal" evidence="18">
        <location>
            <begin position="385"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU000504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF02887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAG0023594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="505" mass="55739" checksum="7BC23C926E8E794E" modified="2023-09-13" version="1">MKDGIMTNLEWTSSLDIDYQPSNTRKTSIICTIGPKTNSVEMLTKLRNAGMNIVRMNFSHGSYEYHQSVIDNTRQSCAVHPGRPVGIALDTKGPEIRTGLMKDDIEVPISVGHEMIFSTHDQYAEACTGEVMYIDYKNITKVITPGKIIYVDDGVLSFKVLAVEDDQLKVQALNNGKLCSRKGVNLPKTDVDLPALSDKDKRDLQFGVKNNVDIIFASFIRRADDVREIRKILGEEGKHIKIISKIENHQGVKNFDEILEVTDGVMVARGDLGIEIPCEQVFLAQKMMVSKCNLAGKPVICATQMLESMTYNPRPTRAEVSDVANAVLDGVDCVMLSGETAKGSYPLEAVRTMAETCVLAESAICYPPLFNELRMLQKRPTETTETVASSAVSAAHEQNAGAIVVLSTSGDTARLVSKYRPQANIVIVTRKESTARAIHLSRGCYPFIYPEPKVDDWQEDVDARLRWGVEQAIEHGLLKAGQPVIVIQGFRAGYGNTNTMRIVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SR46</accession>
    <name>A0A9P6SR46_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine/threonine-protein kinase HAL4/sat4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">SAT4_5</name>
        <name evidence="3" type="ORF">BGZ80_008699</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004800">
        <property type="protein sequence ID" value="KAF9992136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SR46"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="95"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="200"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9992136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="214" mass="24141" checksum="B2C3ED944EA591C4" modified="2023-09-13" version="1" fragment="single">MVTFSTDYWAPAMEVNVRRRQEKSVLYTQKDKKHTSQDEHWSTLRQVPTIDSTTSATSATNVESQNALKKVLFPKPPPVAITNKKQTLIHKIFHHESKSTSPSPPSSPIFTNSPIEQDPHLLNTSSSLEKKNIFNFSNVLGRTASSFGSERSDTKKANCTLLEKYGICDKGNIGQGATAVVRLAHKLSDEDDSEKLFAVKEFRKRRKDETEKEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SRB7</accession>
    <name>A0A9P6SRB7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_008130</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004313">
        <property type="protein sequence ID" value="KAF9993489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SRB7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY MULTIDRUG TRANSPORTER MFSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718:SF9">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY MULTIDRUG TRANSPORTER MFSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="89"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="118"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="148"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="23"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9993489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="174" mass="18652" checksum="C329D17DF4E02753" modified="2023-09-13" version="1" fragment="single">MADSIVKPTLPWYRRLNQMKGLMLVIVSCAQMLDLINVTSVIIILPKIMIDVGYEFDKLQWVSSAYALAYGAFLLLGGRLGDIFGHRNIYLFGVTWFSIWAVINGFAKDPVMMSVGRALQGVGAGFTIPSALAILTTSYPEGPERHKALSIFGGTAAVGSVLGVLLGGILGSTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SRZ5</accession>
    <name>A0A9P6SRZ5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007581</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003906">
        <property type="protein sequence ID" value="KAF9995186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SRZ5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040313572" evidence="1">
        <location>
            <begin position="22"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9995186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="174" mass="19986" checksum="98BC63D84BC56078" modified="2023-09-13" version="1">MVAISNLSILLLGTLAMLASGTTTPAKLTKKQMAQVVDCQVQCIYSKPPFGNKPDFRVDQFMRVKSYGKMPYLVKNMQPIVDPCHDKFVTFHKNITKITEKNFNEYVLCDSKTLTKNEDVYYAKNFNYKKAGFTNKEWTVFRNHTVPGFRRALHNCRGGCRRVHVAHKKVNFKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SST2</accession>
    <name>A0A9P6SST2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Had superfamily phosphatase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_006911</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003447">
        <property type="protein sequence ID" value="KAF9997869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SST2"/>
    <dbReference type="OrthoDB" id="198652at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008962">
        <property type="term" value="F:phosphatidylglycerophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006549">
        <property type="entry name" value="HAD-SF_hydro_IIIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027706">
        <property type="entry name" value="PGP_Pase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010021">
        <property type="entry name" value="PGPP1/Gep4"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01662">
        <property type="entry name" value="HAD-SF-IIIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01668">
        <property type="entry name" value="YqeG_hyp_ppase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19288">
        <property type="entry name" value="4-NITROPHENYLPHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19288:SF25">
        <property type="entry name" value="PHOSPHATIDYLGLYCEROPHOSPHATASE GEP4, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09419">
        <property type="entry name" value="PGP_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9997869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="222" mass="25190" checksum="A7D0B10788AA12A4" modified="2023-09-13" version="1">MGQSFNFQGIIQSFRVLVSPRLMVPNVVVRDIRDINFEQLHKSGVVAIAFDKDNCLTRPYGNDLHPPFKDAWKSCRDVYKDQVIIVSNSAGTNDDKDYNQAKAIEKALQVLVLRHEHKKPAGGEELLKHFSGINPERIAFVGDRALTDVVFGNNYGMFTILTKDIVSEEGDNPMAVKIRKMEHRVLGFLDRMNIRREAHSIPIDKHAVVMQQTPPPQTKEQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ST41</accession>
    <name>A0A9P6ST41_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_006575</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003254">
        <property type="protein sequence ID" value="KAF9999404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ST41"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053013">
        <property type="entry name" value="LAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34815">
        <property type="entry name" value="LYSINE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34815:SF2">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9999404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="171" mass="18191" checksum="07EE1F58D696B79D" modified="2023-09-13" version="1" fragment="single">MSAQVSTTAPVAEKLVGKAKGKPIGPAPYLHEDLILVRATVPEIIQRTWTNNMEEWAKGVPLPQYHAREKHLASTAFSSDNRLITWVLVPKPDADVTDAYKEWASNTSSSTGTGGGGAIVGVSGGFDPSDISQENLERILGAVETYERPGIVATVGDEELKDVSSMSVASV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6STH1</accession>
    <name>A0A9P6STH1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Oligopeptide transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_006355</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003131">
        <property type="protein sequence ID" value="KAG0000515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6STH1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035673">
        <property type="term" value="F:oligopeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004648">
        <property type="entry name" value="Oligpept_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22601">
        <property type="entry name" value="ISP4 LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="52"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="80"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0000515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="135" mass="15739" checksum="777D8637D65C9E8C" modified="2023-09-13" version="1">MYNSINYFFLVGIVLPIPFYYLKKSAKVSWMQYVHLPILLSSIGYIPPANSINYTNWLAVGFVFQYFARRYRPEWHLRFTYVLSSALDSGTVFCTVICYFIFTYNNISMPDWWGTRSDLCTLDGKPWTPVPEAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SU76</accession>
    <name>A0A9P6SU76_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_005992</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002956">
        <property type="protein sequence ID" value="KAG0002331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SU76"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0002331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="212" mass="24137" checksum="13AB43F14D68A0A9" modified="2023-09-13" version="1">MAATHHRKSLEVIMTFDPCNGFYDGDLVPEPIEYVWETDVAVQQLLHTCPCVKEFQLPELEMDLDEVEKAKWACKNLEVFCARIRGLDTKEKITRTLQLWIEGKSKKKKRKKRRLTDNGEMWRRDLVDSKDVEIFAVAEAVAEAEASLPLVQALAQPLTQPSPVSQPPHIPPPPPPVPAVKGGLSIEERVARHLLRFDELKEVWLGTKVWIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SVH7</accession>
    <name>A0A9P6SVH7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005224</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002591">
        <property type="protein sequence ID" value="KAG0006564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SVH7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="113"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="244"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0006564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="361" mass="38725" checksum="AAB014AB6E1992CB" modified="2023-09-13" version="1" fragment="single">MVSVVHFGSRTRNIHDSGTKHKENVERFLREQTQRGKDKEAETARMNKQMDAIEKAAMKQYQLDVEAGLVQPSGSSPTPGKEPGTPPTKATPEQKPPTLLGSKATATGSNADPVATPVAKAEAATATTSKPTRDETVGQPGEWQTVEVPAPRSIPKPEKGDGGSKNENNEGGNHYVQGADDDEGEADPEDLRGFKIVEKTYPVETDVHGDDGEGESTGAAPKMDDFYQFMSPLEGANNNANDRPSTQPTEPESSSAANSTSASSRTSWSAWGASFNKLIERGKKDMNEFVDVTRKDLTELVHTVQQERTTAMETLTKKVEDLKTTLPPIPASVNTASADILGRVSSVVEGIKHELTEAAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SVL1</accession>
    <name>A0A9P6SVL1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AMP-activated protein kinase glycogen-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_005056</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002511">
        <property type="protein sequence ID" value="KAG0007047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SVL1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02859">
        <property type="entry name" value="E_set_AMPKbeta_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032640">
        <property type="entry name" value="AMPK1_CBM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16561">
        <property type="entry name" value="AMPK1_CBM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-activated protein kinase glycogen-binding" evidence="2">
        <location>
            <begin position="275"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="360"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="479"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="818"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="857"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="183"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="379"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="479"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="857"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="883"/>
            <end position="893"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0007047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="893" mass="97703" checksum="4BB666FCF67ED270" modified="2023-09-13" version="1">MLTTQIQLLFYIGKIQIVSCSVFVPVPDIVVKSHQTLENLLPFLPLSLTAAPDPKEEQLQQQQEQQQQQQLLIAPYNDTSSTSLALTTREDVNLSLRGRRQRDSSAVAAITAGAAVTSAATAGGNNGHSQQSNVSTNRISPESSIPATTCIKISLQPVPKFKLVKPKCPHLHQRNKNQRHFRQQQQQQQDPQQSHSHRSQSHSHSHSHHSHSHSHSHSHSHSHSHSHSHSHSHSNRRSTSAMALEYPASSISGRRTVTVKFVYPIGASSPIPEIVQVTGTFNDWQRTDPLTRNLETSQFEGDIVISLDKIVNNNSTTPNIKVLYKFVLDDSNWVTDPKQETDRDYAGNLNNVIYINTAISDQDDQQHTRDGSAAAAAVGEDDEDEEEDEEERLARLKREAEDDATIRELGGGMWGTPFFSVNDPPNLPEHFVNNPNQDLIDVTPVEEPSIEIASVAAPIEEQPQVGVDVEAETTEEVKAEQEEAKAEQEDNQVKERYEGEDEDDRIIRELGGTMWGTPYFQVNDSVQLPEHFTEALGDSNPEDDNTDAEVSVVDRDATTPLPENLYKGEVLSDEINVSMEGTLLETVVETTEDTAIVAPDGTLLEESITTNIQETLSGQVEESVTEVVETVEDIEPATPTTVVVATAAEHSTPEVTMTETESTTAIQGEDGAETLVVEDTLTFSENSGIDSTPTAVVVEEPAVAQQEASAAAETELAVVEDTIKYTDGPEVNSNSLHKLTTAIKPVLRGESLIVEQSPEVNLIISIPEPFMATTGYKLPLIDIISLYTQHNDSSKSKIAINDDGRDSDSVLLLQGQPAILSSSPPSPAPSSLPFSGDEKRPISQRLSIATIESSDTAFTPTSAASTVSTAISQPNEKPEKKKSIWKKIRKVLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SVW4</accession>
    <name>A0A9P6SVW4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004735</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002384">
        <property type="protein sequence ID" value="KAG0007371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SVW4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0007371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="134" mass="14966" checksum="FAE439E97699C9A1" modified="2023-09-13" version="1">MSLLRHTARRSFNAVLANNTTAFSRLTIARGFADHSPQSRGQDNEIKHAPGWRSEDASESEANVKADREDRTPDTNTEHLQRESVEHLMNQVDHAIHGLKEEVQSAKTNVVKNAKEYANKASETVGSVADKFKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SW14</accession>
    <name>A0A9P6SW14_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004494</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002289">
        <property type="protein sequence ID" value="KAG0007574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SW14"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0007574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="456" mass="51526" checksum="4C6BD9FD0D454D0A" modified="2023-09-13" version="1">MAPEENVMSGNESEDNSDDNSDDDSGNEGDYEEDQQAGDQPIDAERPKKRAFKKITYTKSSRMARDADVPVNENAVARKINPTNLMADVVASLYPMRAMKPGRIESCLIHSLKESFLCMNDQDRSLLSGHLLETMHERSKHTLQLMEAGDKSIGTKEWNTNNILLKVIAADTIFQQYLKITSQLQVPLFRLKGRDICDGSFMSQCARTLSDMSRIKTEAGITEIEDRLVQRQSVEAKLGVDDSDVVMEGDSGIPSSSQYAVESFATSVEEAIRNYESAVKAHLVNVASEASTLRSFYGSTRFKQDKYDYREAQRHDLDKAAAAILRMWKHVPDRQPSDEELEKVLDYIDEDIKSVMEVVNGLLNVKGYDWASYLQLMDEIKEHSGIERETFLKSKSVMRRRKKIALSLYKRGFLDLNTLPDDKRNAFLQSPLVIGLGDGDFCSWRDSESRQGLGKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SW33</accession>
    <name>A0A9P6SW33_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_004397</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002244">
        <property type="protein sequence ID" value="KAG0007657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SW33"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015606">
        <property type="term" value="F:spermidine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="entry name" value="Sodium/glucose cotransporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050277">
        <property type="entry name" value="Sodium:Solute_Symporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48086:SF10">
        <property type="entry name" value="AGR155CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48086">
        <property type="entry name" value="SODIUM/PROLINE SYMPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="198"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="243"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="286"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="311"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="340"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="382"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0007657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="450" mass="48618" checksum="8EF3B79C9F1CB70D" modified="2023-09-13" version="1">MPAYVVSAGIVGLVAYSVSCGLPIFLVARVGAVLHRKYPGVLSLGDFVQWRFGTIPMIIVTLVMLFNMFIALCAEYTSIGNLFEQVIGGPRLPVVVVVAVVTSVYTAAGGLYVSILTDVAQGVFGILLLLIMAVYVAVTYRPESLPTPLPEELGPNYWGWAACGAMPISMTCATIFSEGPWQRIWASADEKALRRGSIWGSIALVVVCFLYGFGGFLAMWAGFPLSDPFGSTGFFDLLGAGKATAPGWIVVIAALSVVTMNEGCVDTLQNAIVDTIASRFFRGKSVWFPRILVFLINAPIVFVSLKGYSIVILFLIGNLVCTICAVPLLLGLVTRLEGIVTGWSMVTGIITGFFSIVVFGYIKMGSMSEGLHYTFVESYDWPSFLLPLVFSFIGVFIAAFVEKIIRISFGFSYPVPLNLPPEAAGSEDEVKESLQDAEYANGKAYPHEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-10-08" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXX9</accession>
    <name>A0A9P6SXX9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Elongator complex protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BGZ80_001407</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the ELP1/IKA1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001318">
        <property type="protein sequence ID" value="KAG0010526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="40048at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033588">
        <property type="term" value="C:elongator holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002926">
        <property type="term" value="P:tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056167">
        <property type="entry name" value="A-sol_ELP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056164">
        <property type="entry name" value="Beta-prop_ELP1_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056165">
        <property type="entry name" value="Beta-prop_ELP1_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006849">
        <property type="entry name" value="Elp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056169">
        <property type="entry name" value="HB_ELP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056166">
        <property type="entry name" value="TPR_ELP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12747">
        <property type="entry name" value="ELONGATOR COMPLEX PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12747:SF0">
        <property type="entry name" value="ELONGATOR COMPLEX PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23925">
        <property type="entry name" value="A-sol_ELP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04762">
        <property type="entry name" value="Beta-prop_ELP1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23797">
        <property type="entry name" value="Beta-prop_ELP1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23936">
        <property type="entry name" value="HB_ELP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23878">
        <property type="entry name" value="TPR_ELP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017233">
        <property type="entry name" value="IKAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="ELP1 first N-terminal beta-propeller" evidence="8">
        <location>
            <begin position="1"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="ELP1 N-terminal second beta-propeller" evidence="9">
        <location>
            <begin position="399"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="domain" description="ELP1 alpha-solenoid" evidence="11">
        <location>
            <begin position="704"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="domain" description="ELP1 TPR" evidence="10">
        <location>
            <begin position="928"/>
            <end position="1091"/>
        </location>
    </feature>
    <feature type="domain" description="ELP1 three-helical bundle" evidence="12">
        <location>
            <begin position="1100"/>
            <end position="1277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1187"/>
            <end position="1214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1187"/>
            <end position="1196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1201"/>
            <end position="1214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00029535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR017233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF23797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF23878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF23925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF23936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0010526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1358" mass="153521" checksum="7D15465FEE0B4D69" modified="2023-09-13" version="1">MKNLTLLSQIHLARFGRPVGKDIHHSVDPETGHVYVAYSTGPAEGVLIRISDLQSPFPDITELVTFPPENDVNAEQWGQVVGVKFLVDIQAICVIFSHGDVVLFHNEPTESGDTLEIVGSVDSGISCMAWSPDEELVIMVTGEGSILEMTKDFDVIAENPIDVEETGEDVSVNVGWGKKETQFHGTEGKQAAQRKIDTSTFTYSPDDDDNHRLSWRGDGTYFCCSSKDKRLGRRVIRVYNREAILQTTSESVDMLEHGLSWRPSGNLIASSQRLPHRHDIVFFERNGLRHGEFTLREPNDTVVKELSWNCDSSVLAVWLQRTTGSCIQLWTMNNYKWYLKQELLYNDEGSAVASFQWDVESALVLHVVTESGSYQRNQYCWDNYSNEMLSPENLGTAAVVDGANLMVTPFRVMNVPPPMSAFTLTVPYAIHHVSFSTLHGGDDMAVLLADQRVAFYEVADKTTRPLPEPKLLGLIELADVPSVVVRQIAWARSDTLIGLQYDSDISADSIVIVKLAFDEESKVPKIISKANVPLEGLYQRLYFNQTYGDILLQQADGNLMSVKIEGEEEPTLERWKEIHRLPEGCVWMGTTRIGAGHVEYREKAVIGLARNNRLYVNDRLISSETTSYCLHNHFLVFTTATHSVRFLPLETSLSEFKIVDNSMLPYDESIRRVERGSKIVLALPYSVNLVLQMPRGNLETVAPRAMVLSVTRDALDKCDFRTAFLTCRKHRIDLNILYDHNPKVFMDNVAEFVKQVKEVDHLILFLSSLRSEDVTQTLYPLSGSGSLLKQQPTQNYTRPNGTKGNYKKVVSPELAEKVNQICDAVRKELQTLDRNTYINAVLTTYVRKSPPDLESALLLLAELKDKDQALAEDALKFAIFLADVDRLFDVALGMYDFTLVLMVAQWSQKDPREYLPFLNELRTLEKYYQRFKIDDHLKKYQSALQNLSQAGERYFDDCIAYIKQHNLFKFALKVFGSNPVKHKSVLQIYGDSLSVNGDHQQAAVAYSMAGNKEKALESYKEAGLWREAVVLAQQLKYDPSATAYLARGLAEHLKLDKRYTEAGTLLAEYAKDSEEAVSALLEGRLWSEAIRIAYLYNRHDLMATHITPGIADGHHDLMESIRDMQEQFDKQIKRLKEVRDLRIEKALAEAAEDMAPDDGLDNVDLMSDTTSMASGFSRYTAANSVLSKSSQSSRSSQYTARLKKRNDRKRARGKKGSAYEEEYLISSLRKLIIRVDTTKSDVHALLKCLATSMSLERARVLQQEFGKLLQDIDGHMHIIFVPPTEEYLAKKKAAEDAKNERKKLIRQNQINAHLMSRHEEAVAQAQIAQLEEIAEQEIADIYGEPPVMSKENWDVDLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SY13</accession>
    <name>A0A9P6SY13_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mediator of RNA polymerase II transcription subunit 10</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Mediator complex subunit 10</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">MED10</name>
        <name evidence="8" type="ORF">BGZ80_001027</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the Mediator complex subunit 10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001227">
        <property type="protein sequence ID" value="KAG0011000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SY13"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019145">
        <property type="entry name" value="Mediator_Med10"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09748">
        <property type="entry name" value="Med10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0010">Activator</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="172"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="10"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="201"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0011000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="221" mass="23763" checksum="7EA52CD119FE8932" modified="2023-09-13" version="1">MAPQSTGPISAVPGAAATASAQQQQQQPDASDAASVQNEQIRQDLELKLQEMIECLLELSITVYDFQSESNSLVHQKIQELITQLSDIEGFKDKLDMMVPWEVLGYIEDGKNPDLFSKSFVEAVAGENQFTNGKITALKAGSFESALTQNLGSFFPDEMMDYNQLVASASTSDNTTAPRLEHPNDVSTTVKQEVEDGSFLTVNNTVSTTSSAGSSSVSPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYC7</accession>
    <name>A0A9P6SYC7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ubiquitin-like-conjugating enzyme ATG10</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Autophagy-related protein 10</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_000799</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATG10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001175">
        <property type="protein sequence ID" value="KAG0011287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYC7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061651">
        <property type="term" value="F:Atg12 conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032446">
        <property type="term" value="P:protein modification by small protein conjugation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1460.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007135">
        <property type="entry name" value="Atg3/Atg10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14957">
        <property type="entry name" value="UBIQUITIN-LIKE-CONJUGATING ENZYME ATG10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14957:SF1">
        <property type="entry name" value="UBIQUITIN-LIKE-CONJUGATING ENZYME ATG10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03987">
        <property type="entry name" value="Autophagy_act_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0072">Autophagy</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0011287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="99" mass="10741" checksum="B752549308FAEC78" modified="2023-09-13" version="1" fragment="single">GAAISLNEIYGSLVPEEWRSSIMNAGLNGGISQQDHPILNVPYFYMHPCETVPLMETVQSNQSFENATSFLDSYIMTWLSFTGQAIGITIPTGVVAGTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYE8</accession>
    <name>A0A9P6SYE8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein-tyrosine-phosphatase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_000518</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001108">
        <property type="protein sequence ID" value="KAG0011658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYE8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140096">
        <property type="term" value="F:catalytic activity, acting on a protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990444">
        <property type="term" value="F:F-box domain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062026">
        <property type="term" value="P:negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070372">
        <property type="term" value="P:regulation of ERK1 and ERK2 cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052449">
        <property type="entry name" value="STYX-Interacting_Phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46588">
        <property type="entry name" value="SERINE/THREONINE/TYROSINE-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46588:SF1">
        <property type="entry name" value="SERINE_THREONINE_TYROSINE-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01908">
        <property type="entry name" value="ADSPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="2">
        <location>
            <begin position="35"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="3">
        <location>
            <begin position="101"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0011658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="174" mass="20392" checksum="AF3061655EAD36D2" modified="2023-09-13" version="1" fragment="single">MEQAENTFTNKPDLYRHLISQNTPVLEWRYEQRREMQEILPSIFLGPYSATRNLDELKRAGITHIITLWDISESRILKVHHPEHFKYLQLEISDAATQNLITLFPSVKQFIDQAILEEDGKVLVNCMSGISRSPAFVVAYLMEATGMEYEVVYRYVQNKRFCMNPNPGFRHQLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYE9</accession>
    <name>A0A9P6SYE9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">diphosphoinositol-polyphosphate diphosphatase</fullName>
            <ecNumber evidence="1">3.6.1.52</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_000717</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>1,5-bis(diphospho)-1D-myo-inositol 2,3,4,6-tetrakisphosphate + H2O = 1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate + phosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:79699"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:74946"/>
            <dbReference type="ChEBI" id="CHEBI:77983"/>
            <dbReference type="EC" id="3.6.1.52"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:79700"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>3,5-bis(diphospho)-1D-myo-inositol 1,2,4,6-tetrakisphosphate + H2O = 3-diphospho-1D-myo-inositol 1,2,4,5,6-pentakisphosphate + phosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:56312"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:140372"/>
            <dbReference type="ChEBI" id="CHEBI:140374"/>
            <dbReference type="EC" id="3.6.1.52"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5">
            <dbReference type="Rhea" id="RHEA:56313"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate + H2O = 1D-myo-inositol hexakisphosphate + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22384"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58130"/>
            <dbReference type="ChEBI" id="CHEBI:58628"/>
            <dbReference type="EC" id="3.6.1.52"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="4">
            <dbReference type="Rhea" id="RHEA:22385"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>6-diphospho-1D-myo-inositol pentakisphosphate + H2O = 1D-myo-inositol hexakisphosphate + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:79703"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58130"/>
            <dbReference type="ChEBI" id="CHEBI:230534"/>
            <dbReference type="EC" id="3.6.1.52"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:79704"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the protein-tyrosine phosphatase family. Atypical dual-specificity phosphatase Siw14-like subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.52" evidence="1"/>
    <dbReference type="EMBL" id="JAAAID010001156">
        <property type="protein sequence ID" value="KAG0011400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYE9"/>
    <dbReference type="OrthoDB" id="6375174at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052840">
        <property type="term" value="F:inositol diphosphate tetrakisphosphate diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14528">
        <property type="entry name" value="PFA-DSP_Siw14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.190.10:FF:000024">
        <property type="entry name" value="probable tyrosine-protein phosphatase At1g05000"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020428">
        <property type="entry name" value="PFA-DSPs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004861">
        <property type="entry name" value="Siw14-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31126:SF48">
        <property type="entry name" value="INOSITOL PHOSPHATASE SIW14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31126">
        <property type="entry name" value="TYROSINE-PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03162">
        <property type="entry name" value="Y_phosphatase2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01911">
        <property type="entry name" value="PFDSPHPHTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="8">
        <location>
            <begin position="77"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00044949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0011400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="243" mass="27634" checksum="C07880404B692C2F" modified="2023-09-13" version="1">MTSVLAPTAAPDTFAASNVISTNYDNNNTNDTHNPNLAAQEVSTSISIPKTITIDPMDLGATGESLSYPEDLCPPDNFNMVSTWIYRSSFPKKKNFSFLKKLGLKSILTLILEDYPDQNMKFLKENNVKLFQFGIAGNKEPFVQIPDDKICDALAVLLDRRNHPILIHCNKGKHRTGCLIGCLRKLQHWSHTSIFDEYRRFSHPKSRSMDQQFIELFDSREAWKVIDPKWIPDWKTLGHHAGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYT5</accession>
    <name>A0A9P6SYT5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_000313</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001060">
        <property type="protein sequence ID" value="KAG0011958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYT5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0011958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="274" mass="30422" checksum="2112E6124B89C105" modified="2023-09-13" version="1">MENEIATTTSTPAFSSPESLSYSGMTSVSHVQKLSYESGREMTEARNLFNGDNSDKRQHIQHYLLHYGADQPTLPNKDNSIISSSTALPRYDIQSRSNLQRGPPGGGYAFKRSMKRKATWEDEEMMMDSLDAVDPGSVSAPLSQQSIQTASAQDRRMSQVTEIQDQEMNCDRYDCEPMTATPEDCSSGQMSVDIGTPSSVDQQDFERSDSNNHNEGDSGMMGPIWSAKRTKPRLELVAIPGSAFAEMEARRREAGQIELDIFQQCFYNAAATSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZD3</accession>
    <name>A0A9P6SZD3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">UDP-glucose 6-dehydrogenase</fullName>
            <ecNumber evidence="3 8">1.1.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">UGD1_3</name>
        <name evidence="13" type="ORF">BGZ80_011115</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>UDP-alpha-D-glucose + 2 NAD(+) + H2O = UDP-alpha-D-glucuronate + 2 NADH + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:23596"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58052"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="1.1.1.22"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Nucleotide-sugar biosynthesis; UDP-alpha-D-glucuronate biosynthesis; UDP-alpha-D-glucuronate from UDP-alpha-D-glucose: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.22" evidence="3 8"/>
    <dbReference type="EMBL" id="JAAAID010000854">
        <property type="protein sequence ID" value="KAG0013372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZD3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003979">
        <property type="term" value="F:UDP-glucose 6-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006024">
        <property type="term" value="P:glycosaminoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.100:FF:000001">
        <property type="entry name" value="UDP-glucose 6-dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000032">
        <property type="entry name" value="UDP-glucose 6-dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000114">
        <property type="entry name" value="UDP-glucose 6-dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.100">
        <property type="entry name" value="Cytochrome c1, transmembrane anchor, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
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        </submittedName>
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        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="4">NRRL 2769</strain>
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        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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        <property type="project" value="InterPro"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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    </dbReference>
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        </source>
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        </source>
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        <source>
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    <sequence length="459" mass="51355" checksum="D2D024045B7811E1" modified="2023-09-13" version="1">MGPLLDRSLKALVSWRLSFGENEQLENDGDIDDDEEDLDAFGERGANIRGLLEHIVGAHNQQRKTSRSKSSQSTSKGSGKKKKGKKQIQDFLSIQDVKEEIRQLEPDFDSALVNATAGALYKSLVQNLKDRNRSVVLNQVQEDEEEEEKHGDQTLESKQDTKEQLGVEHLPPAIHSLAKRIELSSKGIDVFEDASVKNSLSKYLLQSWCVELLDLIILHLASLEKVSSTLVTDTLSEVFETRERHCKSYAEHCSQTSTVSGGQGPFVIPTEDATVLLKLVSQDMIDSLKKLRKLTAGSCKQKSLVEYLDVWSILSKESKLELGTAEAGKDDSQLLTEHLKELSQVLRGIQPFADTALMLHIVTLIAFQRWTGSMLHASGKFVPRILRQLRLSVEQQPELKQTAESQLGSLEKMMDFVLSNVKQQQQQQSEGSEQEDEQLNPDQMWQSVYDIGASLSTPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZK5</accession>
    <name>A0A9P6SZK5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">W2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_011483</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
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            <taxon>Mortierellomycotina</taxon>
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            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000929">
        <property type="protein sequence ID" value="KAG0012822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZK5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003307">
        <property type="entry name" value="W2_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02020">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51363">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="W2" evidence="3">
        <location>
            <begin position="399"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="290"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="356"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="590"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="647"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="707"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="140"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="290"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="309"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="336"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="357"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="652"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="745"/>
            <end position="759"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0012822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="759" mass="83646" checksum="72D86935B80D5023" modified="2023-09-13" version="1">MTLVNTDSTKPNLSIAKNARRGQPKQTCAATESLSSPVTDAAAVVVSVVDAQPEHPSKNVILYSSVNPSISSEEVDDLSSPMGTSVDSNTNDVFDADEMELQHSNDLDSLMTEVETPQYPLPMHVARRPIIDSSLKLERKSRLRRKIDRLQAKNAALKSTVTQVKSDLALERQKRSNMDQIYSNIRKDLSQKLENEEIKVLNLKAEMEQMAAEMKKLKNQLATAKARASAGGKGSSMGYKIGYDSSAFSLSSGISNVGGLMLHHANLAMISCQDDSEEFLLSHSYSSATIRTSPSLSTNPGIAAMSCSDNEDEGMDDEGQSDDEEGTLLFTQNPKSSTPSSSRRASISSVSSLLTLVEEESEEQSEDDDSDDEHEDAPCTMMEIILQRQQARSPEDDMENPPADANETFETMAQNALFQAIQSKSTVGQAHLQLEELVLKYNARLEQAVDVIAKEVSRWWEDERLATGGPISGGWGTENVVINKETGELANPKVSVEKRMESFFGPLLLQFVASLAEQKMLLEKLGNYARVDSRWLKNHNAMLVALYKFDVVEAEAVLEWWKALEEPQGVFGHGGNNLRSLNSRFVAWLEDEEDDSESESDDEEDGSDNDSCSDSDDSDDDSEEDDSDDDEMEQDDNVVDAILDMAYPPTSTREDTGMAKESNSNRDQESKSSPRSSGDDNAGMAAGPTKRRISFCTNNLYYSYDGRICRKKDPSVGEDGEQQENANKKKYQQCPPFRAPGSEAPESDVESATEEDRSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZK9</accession>
    <name>A0A9P6SZK9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_010657</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000766">
        <property type="protein sequence ID" value="KAG0014084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZK9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="6.10.250.3260:FF:000001">
        <property type="entry name" value="60S ribosomal protein L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3260">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0014084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="50" mass="5596" checksum="CDF7D740B2533181" modified="2023-09-13" version="1" fragment="single">ENAAAKLKAKTDGVKVNLKRQPVQPREARFVTIKHNIPTTLNPIPYDTLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZM1</accession>
    <name>A0A9P6SZM1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PAS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_010597</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000754">
        <property type="protein sequence ID" value="KAG0014179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZM1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="299"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="303"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0014179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="346" mass="40072" checksum="E271362B4A8B4D7A" modified="2023-09-13" version="1">MASLMGSEKEELERISRNHKNVSSTWNPAKLDMELRACLFLNRFTRNLCVMYASPSCEMVLDLDPDDLLGKPLLLYIRADDLASFVAQADLAKSTATVRHLRFWFQSPNCRQEIPLEAIFLGAADALVAVFRRCLPFRRKQFITNFSSQEYSTRRNSGKFSRNYSFSSRISRSRGSSFERSEPYGRIRHVYSIRDSPTDTFSSSSSSISSTQNQGTRSYQASLQNVPVGSISSIRSLDKEQARLRPLTSFHEEETDVLKSKAKHLLREFRTQDSEVETCLVEEFEKVRLVPDRTKAIRRERGTEEEEHSEVEDDDYYDEVPEITIPDESIEEILMPYSMRRHWKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZM7</accession>
    <name>A0A9P6SZM7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Peroxisomal trans-2-enoyl-CoA reductase</fullName>
            <ecNumber evidence="13">1.3.1.38</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">BGZ80_011409</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Participates in chain elongation of fatty acids. Catalyzes the reduction of trans-2-enoyl-CoAs of varying chain lengths from 6:1 to 16:1, having maximum activity with 10:1 CoA. Has no 2,4-dienoyl-CoA reductase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>(2E)-decenoyl-CoA + NADPH + H(+) = decanoyl-CoA + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:44960"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:61406"/>
            <dbReference type="ChEBI" id="CHEBI:61430"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="19">
            <dbReference type="Rhea" id="RHEA:44961"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>(2E)-dodecenoyl-CoA + NADPH + H(+) = dodecanoyl-CoA + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:44964"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57330"/>
            <dbReference type="ChEBI" id="CHEBI:57375"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="15">
            <dbReference type="Rhea" id="RHEA:44965"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>(2E)-hexenoyl-CoA + NADPH + H(+) = hexanoyl-CoA + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:44956"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:62077"/>
            <dbReference type="ChEBI" id="CHEBI:62620"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="17">
            <dbReference type="Rhea" id="RHEA:44957"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>(2E)-octenoyl-CoA + NADPH + H(+) = octanoyl-CoA + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:44952"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57386"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:62242"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="20">
            <dbReference type="Rhea" id="RHEA:44953"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>(2E)-tetradecenoyl-CoA + NADPH + H(+) = tetradecanoyl-CoA + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:44968"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57385"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:61405"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="16">
            <dbReference type="Rhea" id="RHEA:44969"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>a (2E)-enoyl-CoA + NADPH + H(+) = a 2,3-saturated acyl-CoA + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:33763"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58856"/>
            <dbReference type="ChEBI" id="CHEBI:65111"/>
            <dbReference type="EC" id="1.3.1.38"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="18">
            <dbReference type="Rhea" id="RHEA:33764"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Interacts with PEX5, probably required to target it into peroxisomes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.38" evidence="13"/>
    <dbReference type="EMBL" id="JAAAID010000914">
        <property type="protein sequence ID" value="KAG0012933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZM7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019166">
        <property type="term" value="F:trans-2-enoyl-CoA reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052388">
        <property type="entry name" value="Peroxisomal_t2-enoyl-CoA_red"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24317">
        <property type="entry name" value="PEROXISOMAL TRANS-2-ENOYL-COA REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24317:SF7">
        <property type="entry name" value="PEROXISOMAL TRANS-2-ENOYL-COA REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="21" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0521">NADP</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="21" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="21" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00037124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00038622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00038849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00041063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00049108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00049251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00049386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00049559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAG0012933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="303" mass="32290" checksum="C78C55A35E2AC441" modified="2023-09-13" version="1">MVLIGSHPILGFAVYFYSLGATVILAARKMDQLKSTAKEIELLGGKCDVMQLNIRDANQALEAVNQIVAKHGKLNGLVNNAGGQFHSPASKMTPNGFATVVDLNLMGTFYLCKAAFDGYMGEHGGTIVNIVADCRNGFPGMVHTGAARAGIINMTKTLAIEWGPYNGIRINCVAPGMTISSGMKNYPEKVLDGFIANGWMNPSGRFGTESEMAASVVFLLSPAASYITGVNLPVDGGYSLSRSDAKGPEAMYNPKGSLMRPYIGWPSDEKAAIQEVDAPTGIVKLFEKYKALAVNGINRDSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZR8</accession>
    <name>A0A9P6SZR8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">small monomeric GTPase</fullName>
            <ecNumber evidence="2">3.6.5.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BGZ80_010420</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="11">Endomembrane system</location>
            <topology evidence="11">Lipid-anchor</topology>
            <orientation evidence="11">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.2" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010000723">
        <property type="protein sequence ID" value="KAG0014468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZR8"/>
    <dbReference type="OrthoDB" id="5976022at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003925">
        <property type="term" value="F:G protein activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04139">
        <property type="entry name" value="RalA_RalB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000203">
        <property type="entry name" value="Putative ras-related protein ral-a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020849">
        <property type="entry name" value="Small_GTPase_Ras-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24070">
        <property type="entry name" value="RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0488">Methylation</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0636">Prenylation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00046278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0014468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="194" mass="22195" checksum="987156EED1819F25" modified="2023-09-13" version="1">MGKKAKQDLPLHKVIMVGSGGVGKSALTLQYMYGDFVEEYDPTKADSYRKKVTLDGRDCQIDILDTAGQEEYAAIRDNYYRSGEGFICVFSLCEYESFMHTQEFKDQISRVLDDDKIPFILVGNKADLTQLRKVNQGDAAARATEWNCPYYETSAKTRLNVDEVYTVLMRKIQQRKESAKDRERKGKKGKCMIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T024</accession>
    <name>A0A9P6T024_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_010205</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000687">
        <property type="protein sequence ID" value="KAG0014824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T024"/>
    <dbReference type="OrthoDB" id="2442713at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="135"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="376"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="213"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="295"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="323"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="384"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0014824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="418" mass="44482" checksum="7ED4FF7D8C48906A" modified="2023-09-13" version="1">MAHCSDVKTTGVSKQTLTNDAFTYSTTTTSNGLCVVHGQGSSGSCVATATMSCKSISIVNLAPAPTTSASSTIATGLAITQSSGSGPASLPSQTQSTITTLPLAMPAPIEPSAAPASPSGDANSNSNNHNNNNNLPAIIGGSVGGAVLLIAIVAFILVRRRRRMRKHGRDRYMVQVKGEPDLDEKLVGPQKQQHTGSNVSDGGFNGVAMSPFQQQQQQQQQQQQQQQQQQYQRAMSPPIPPRTESRLSNKSGNLNSQTQLRPGTPSSTLSYNKHSGGPGPGPCPGQAATKIDYTPRSTYIPATQKNNPNPRKVPPPSVPPHLQGTQSGNNNGQESTELYIDLIPVEETPRIANAILPEDPNANQAYHQMREEQINRNRSMGRNAGYGGNSGGGEYYSKALIDDDEEVNEDDIMYLPIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0A7</accession>
    <name>A0A9P6T0A7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_009656</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000598">
        <property type="protein sequence ID" value="KAG0015750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0A7"/>
    <dbReference type="OrthoDB" id="2432201at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="9"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="77"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0015750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="157" mass="16187" checksum="8032670E100CF8EC" modified="2023-09-13" version="1">MDVVRITQALRQQQQPGRLHSSRGGNNTHSADISASSNEPIPIRRPTWDNTLNINTASATASVLGHEVSHMEQNNGASPSTSTSSSRVTPTSASPSSSFFNLPSPLSLAAGFFSGGNTGGVVASASSAATASGANMGEIESLLLRSMPMFGNLVSRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-06-18" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0Q6</accession>
    <name>A0A9P6T0Q6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Multidrug resistance-associated protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">ABCC1_2</name>
        <name evidence="13" type="ORF">BGZ80_009135</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000523">
        <property type="protein sequence ID" value="KAG0016560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18579">
        <property type="entry name" value="ABC_6TM_ABCC_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18603">
        <property type="entry name" value="ABC_6TM_MRP1_2_3_6_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000001">
        <property type="entry name" value="ATP-binding cassette subfamily C member 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000006">
        <property type="entry name" value="ATP-binding cassette, sub-family C (CFTR/MRP), member 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000997">
        <property type="entry name" value="Multidrug resistance-associated protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000163">
        <property type="entry name" value="Multidrug resistance-associated protein member 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044746">
        <property type="entry name" value="ABCC_6TM_D1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056227">
        <property type="entry name" value="TMD0_ABC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF443">
        <property type="entry name" value="MULTIDRUG-RESISTANCE LIKE PROTEIN 1, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24357">
        <property type="entry name" value="TMD0_ABC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="26"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="64"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="92"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="126"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="164"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="282"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="319"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="394"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="422"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="499"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="992"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1095"/>
            <end position="1115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1187"/>
            <end position="1206"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="281"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="651"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="960"/>
            <end position="1236"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="1273"/>
            <end position="1545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="625"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="880"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="625"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="910"/>
            <end position="923"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0016560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1552" mass="173608" checksum="81E3F23675651048" modified="2023-09-13" version="1">MSDSYCRDQEGWGPTSSERVDLTPCFEYTILATLPACIFIVAFIYRIQYLLRYGKPHNYGRTNLIFWCSQVLMLTAAVILFVRAGLTGKETYGSTAAILVSALMGVAWTLAIPLNVLEHRYEIRSSTAIFSYYVISVIAGAITTRTLSMTQNASQATNSATTNTLYYIYFGVISLGLIVEAWPRGRTKVQQKSGAGPYEKANIFSRYWFHYLQHVIALGYKRPLQQVDIQDMMPKRINTKFSYIYLSEQWDRHVAKRKAKGKEPRLVTLVLKAYGSQWIPIVIYRVLASALGFVAPVLMNQLLSFTASYSTDSPQPVPLGIVLSFGMFFSTIVSALLEGQFLQLVTNMGIEARTALVSMVYRKALKLSPAARQTQTPGEITNHMSVDAERWAEALPLLPMWGSIPLEICIALWLLYLQLGWASLAGLATIIAVAPLQAWIAAFFSVAKEQKLEAMDNRIRITSELMSSMKIVKLYGWESSFLSKVAVYRKRELSILRKMGVAFSFMTIMFSSITLLMALVSFSIYATVGGPGRTPGEIDSQTIFVSITLFGLLNRPIGMLSHITGETVSLIVATRRIETYLLEEELSDDQIQRFDDIPSDASQPVIDIQDGVFAWDKEGPTVETEKQIKAREKKEAKKRKQEAKEAKEAGLHVPIAVESVKRSYEATLKNINLTVQKGHLTAAVGRVGQGKTSLFDAIIGNMYKRQGTVKIYGKVAYVPQQAWIINSTLRENILFGAQFDQERYDTIIHATGLIPDIDMLPAGDQTEIGERGINLSGGQKQRVSLARAAYLDADIYLLDDPLSAVDAHVDQHLWQNLIGPKGLLKDKTRVLITHGIHHLSEADQIVVLKDGMISETGQYQELLDAKNGFYQLIEDYSVKESTSKEQDDSLSEEGTVQETRIESESGPASRGEEKHVEKVDEKLDDNAGLTEEEKMKIGSIQWAIYKIYAKAASYRNVVQILSLFVVLEGCQIGTNIWLERWIGIADTSNRGVGYFMGVYAVLVVTFMLLVVWTSYTTMVTAGVRAAAFLHDRLLNNVLRLPMSFFDTTPVGRIVNRFSSDCYSADEEICWAFHDMFFCFVSVFGSIIVIAVTTPLFLVIIPPIIFVFTLLQRYYIASSRNFRRIESITKSPMYQHFAETLSGASTIRALQCSERFIEQSATRSDQTSNAHFVWATGNRWLNVRLESLGSVIVLGASLFAVFGRNSLSPSMVGMSLSYALNITQDITWLVRCMCEVQFQMVAIERIDEYCNKNQEAPNFTDVQLPESWPTHGHVQFKNYSTRYRQGMDLVIRNVSFEVQPGEKIGIVGRTGAGKSSLTLALFRIIEAANSYWAKASHNGFDSDADPDKLGGDIAELEKVQVDVDEDGGSIWIDGIDISTVGLEHLRRHLAIIPQDPTLFVGSVRNNLDPFEEATDAEIWEALERAHLKDYISSLAGGLSHEVTQNGENFSVGQRSLICLARALLRKTKILVLDEATAAVDVETDELIQKTIRSEFKDRTILTIAHRIKTVMDSDKILVLEKGRVQEYQAPLELLKRKESLFYKLAEQAGEVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-10-08" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T197</accession>
    <name>A0A9P6T197_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">PHD-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_008498</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000462">
        <property type="protein sequence ID" value="KAG0017240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="436852at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048188">
        <property type="term" value="C:Set1C/COMPASS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037869">
        <property type="entry name" value="Spp1/CFP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46174">
        <property type="entry name" value="CXXC-TYPE ZINC FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46174:SF1">
        <property type="entry name" value="CXXC-TYPE ZINC FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
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    <keyword evidence="4" id="KW-0862">Zinc</keyword>
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            <begin position="258"/>
            <end position="309"/>
        </location>
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        <location>
            <begin position="1"/>
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        </location>
    </feature>
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            <begin position="135"/>
            <end position="169"/>
        </location>
    </feature>
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        <location>
            <begin position="196"/>
            <end position="251"/>
        </location>
    </feature>
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        <location>
            <begin position="320"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="403"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="651"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="857"/>
            <end position="987"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1011"/>
            <end position="1067"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1103"/>
            <end position="1149"/>
        </location>
    </feature>
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        <location>
            <begin position="1221"/>
            <end position="1349"/>
        </location>
    </feature>
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            <end position="1426"/>
        </location>
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            <end position="1612"/>
        </location>
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            <end position="1806"/>
        </location>
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            <begin position="1"/>
            <end position="27"/>
        </location>
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            <begin position="35"/>
            <end position="63"/>
        </location>
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            <begin position="106"/>
            <end position="118"/>
        </location>
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            <begin position="223"/>
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        <location>
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        </location>
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            <end position="701"/>
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            <end position="714"/>
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        </location>
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        </location>
    </feature>
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        </location>
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        </location>
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        </location>
    </feature>
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        <location>
            <begin position="1246"/>
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        </location>
    </feature>
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        <location>
            <begin position="1263"/>
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        </location>
    </feature>
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        <location>
            <begin position="1276"/>
            <end position="1302"/>
        </location>
    </feature>
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        <location>
            <begin position="1303"/>
            <end position="1332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1542"/>
            <end position="1554"/>
        </location>
    </feature>
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        <location>
            <begin position="1673"/>
            <end position="1686"/>
        </location>
    </feature>
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        <location>
            <begin position="1699"/>
            <end position="1713"/>
        </location>
    </feature>
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        <location>
            <begin position="1778"/>
            <end position="1796"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0017240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1910" mass="206308" checksum="E456F410F77535CD" modified="2023-09-13" version="1">MLDSDSGSSELSDASSLSSDNSSGSEADVSKDKPQSTALRNKQQYSTLNRPSLNPSHPPLTSTHRIRQHGAHASLSLSASGSDDGSNSEESSGADEDIAHNRKNAKSSSPNAPISLSASKPVYSQEVMNRSMMLMPANAKYNAHSQTPTSSRGRGRGRGRALLSGHRPHKYDATSTTVIDFEGFSTALEDSKETKELASSKAATPASVSDAASTTDVVRKKKGADQSKLKDSRSTSGTNGKQKLGSRKVGRPKSVSKDVYCVCRGPYDGVEFMIACDRCEEWFHGRCIEMKPQEAKKSSHYYCDTCQKIRRMFGVVTAPEEYSKPSKSTGKIKKSSEKRSGKQHAGVSSSEDRLPLLKIKVESSSRNSQSYNANPISSFANSTSAQAATDPTPFLHRTQIQPHFSSKPASSPSRDHIQSSAALKQIPDMVEDRDVRYVTHYDTTSITSVSRVVIHWGLTNKDDHFRTSIADTNYFLPDRVSQDDDEEDICPICDFECTCNANNNEDSMRVTSPVAKSMSNADDVHALTAIKVPFQPSLGLQSGSATHDSDAVDAENHRSFLNAEKRPVIRAESSSTTLDEAFHTSAKNPMSIPSTQRRLSVIRRGGKSIGKYPMKESRSQYGAYSRGKSIKSGKANIFIYKDSRIDLESDISNEFSDDDDDQDALDSDQGGFSHSLDDVTPTQTPTRYESDAESDGADDMNDSLSMGSSSSLSDVEGDSARPIGDLSPRPKGSGKIVIGKKWSRPHVSNSTGLSFVESNSTAERSQVVKKRGPGRPKKIRDPLIVSREDEMTLYTPAVAARKLIATYPQKGESSKPIRVTVKPKARAELPFIAYDPEVAEDVMALNSLDNENEVRDGTAKAAIATPQASGSRSEAFSEGDIFGDGDLSDELSGDLSDIMSEDFDDLSGESLDFSSSDEEDETSSSSPREFNYSEMEEQDESLVDSDSSLNSITSDSSDSSDLETETASDEDEEIVVYDHEGSEESIDEEELLILEEQERLILAKAHGLLDVFSEEDSDPDRNPFESSEDDDDDEEDERVFDGDDDDVYSDEYYDDDYPDDEYEEMDEQAILAQLKGVQSDIQALMMIPPEQQEQLLLLQHYEEAHRQQQQQDRLQPQGQEQLSQDQFQNSQSQETQSQELDPQQGAQMANLLETSSFLPQFDINVPDLDAVSQQLAASLADSIAKSMAGAKQALEGSLLSEAAMDGDISIQPIDPISTESSIGAPLNVSPRSTSSLSPGPLEETWSAPLPSSPNSLDSNSASIPTPANTPTPSGAITGTSPSIPGSSGMESQQQSPGGSSSGLAQKQLVSQGKIQSLSHSPTYKPLTSTAVSTIGGPSIQPIQPRLSSGEKFPESFTRIQDAGSAAFKEEAQKALDGIGGNCSNLDKSIIPESEMGTIDAPKIGLDSGNTSDDTSLDAHTAETRKRKGEDIMLKETRSCQGKRRHLLIGSTKGDLKNETLISVPTPESEVSLPSSSLSSPPVSSLSVESITPFHVTTTNSSVDSPSSFSVTPTAELTPPLVYDFTKAVMPFMDPSARIFSSNVTQRRGSASQSLRMRKNSLKGKEPKQQTDVMPMDDLLDTSALYGRSSSRSPSPDRAEVGEEGDNEISRSMLKDLNRWERVPIGTFRRSRRPSSPYVGLQGALKFGNATMPATLLADHQQHQQQLHRESQRRIHKRPPGARKHRNPTPLVSDVGSQGRRPEDLSQSLHGDKLLRRRRRAGSSSNGSLTHIPRLGSIGGLHMPSSGRRISKYAGSGLSSDMHVGLGVGLGGLTDSGITMDSTSNSSSSASRTISSSGVGGVGVGKDTDNTSGIEALKDLMTDSSQLPSSACPTPLHSPLFSATTAGSRVLHHSSGEPVVMSEDQSMGKVDGIDSRGEDSIVSHLELDIGKEMDGFHESLLAKTKAKSDKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1D0</accession>
    <name>A0A9P6T1D0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_009021</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000511">
        <property type="protein sequence ID" value="KAG0016687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1D0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.510">
        <property type="entry name" value="Single helix bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051694">
        <property type="entry name" value="Immunoregulatory_rcpt-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549:SF30">
        <property type="entry name" value="MID2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549">
        <property type="entry name" value="PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040219189" evidence="7">
        <location>
            <begin position="36"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="153"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="38"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="124"/>
            <end position="149"/>
        </location>
    </feature>
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        <location>
            <begin position="197"/>
            <end position="218"/>
        </location>
    </feature>
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        <location>
            <begin position="380"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="41"/>
            <end position="109"/>
        </location>
    </feature>
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            <begin position="199"/>
            <end position="210"/>
        </location>
    </feature>
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        <location>
            <begin position="380"/>
            <end position="402"/>
        </location>
    </feature>
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        <location>
            <begin position="434"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="509"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0016687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="527" mass="56150" checksum="C7F41C22980637F5" modified="2023-09-13" version="1">MIKMNLQRRKNFSSSSAMTLAAYLSFLVPAGLAQGQSPDLTTPVHTTDPTTTVATTTTTTTTTTTTTTTTTTTTTTPSPTTISITSSPSISPSTTTDLPTSSLVPTTSVPTTSAITLPFTSTTSTTTFSNPTTTSTNTPVPSSKDSSSSNVPVIVGVVVGVVAVIVVVAITIICFRRRKRGSELTFDTLQGMSAAGASTAPSRQHFNNKAGNPIGRASLGSGAYDDGYDYESQVGAGQGYPSQSGGYGSDIGYDAYGAPHQGYQNPSIFQEDSLAYSNNMNRSRAQGYDQQNLPEIMYRNGNDINEYPGGATGYYDDSAYGQGTWNQGLWVANPEAEKQYQQQPQYQYEQYPEQYPEQYPEQYPERQGDIELQQPRVSYEKSSMNQFDNSSDTAVGSISSPNSKHHGQNPQAIPESPRQLRGGDLFGQDANSNASMSPRIAAATAASGAGIGAAGSQDSSSSPRLASRAEMRSFESARITPPRSSVEGAQSYATEFAAPSRPSLSGDRPSLEGVKKSLRTQRREDWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1M2</accession>
    <name>A0A9P6T1M2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cyanovirin-N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_007401</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000378">
        <property type="protein sequence ID" value="KAG0018249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1M2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.60.10">
        <property type="entry name" value="Cyanovirin-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011058">
        <property type="entry name" value="Cyanovirin-N"/>
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    <dbReference type="InterPro" id="IPR036673">
        <property type="entry name" value="Cyanovirin-N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08881">
        <property type="entry name" value="CVNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01111">
        <property type="entry name" value="CVNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51322">
        <property type="entry name" value="Cyanovirin-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyanovirin-N" evidence="2">
        <location>
            <begin position="549"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="490"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="490"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0018249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="650" mass="68463" checksum="0F53D57D31510C1C" modified="2023-09-13" version="1">MGDSAVITQEPDHFASARWLSSQLHTRDDSNIKLNYTIGGLSPVTQGVSHKASAPSVYQGSILISGPASRVNDLGHRSSPWTIVGCNSSPDLINGQTVLAYCSSTNPKVKCAGVFVGGAKNTIITLPATCGAPFGRIVTLVPTSTSKLPRSVLAQLGRSAKDVSVFTLKFDYNYENIPYKSGDAKVNFAIDIGTLHGGVNPTSVSKRSDSDLQIQKRSDHDKEKDIKVEKEIKYILADVHEKKKGVKVDLKATVEGKFEGSLAFGYHITGTIIPPKLKQHSALMKSDSSISAKLSLTGLAKYTFPKKDVKVVPKTGLPGFSVPGLITLDPFVEADLKFSGDIDLNGSAVASTFATLPSIELSIGDSGLKKPTIKGVESGGLKVTQHLDLSATLKMDLEPKLAIGIKVLKKVVDAEIALVPNFALIAKGEVELGDGPISAINPCIELDGKLALGYEISGKMGGWGAPKSGDFWSLKEPLYKKCLQKPTPTTTIVSHTPTTTTTTTTTATPSPTTTTTTTTTTTTTTTTTTTTVPPTPTNPPCAAAGGDTALMDTCGFYMDGTVVTGFCQNLSCDTTTSTIDLNNYIGNNNGILTFGGSDFIATCSIDWLHGPALQAECQDSITGTTVTANIDISSNIGNINGMLTYIASNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T287</accession>
    <name>A0A9P6T287_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Chromatin remodeling complex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BGZ80_005434</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000268">
        <property type="protein sequence ID" value="KAG0019675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140658">
        <property type="term" value="F:ATP-dependent chromatin remodeler activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056616">
        <property type="entry name" value="Chromo_MIT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003226">
        <property type="entry name" value="MYG1_exonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
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        <property type="entry name" value="SNF2-like_sf"/>
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    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
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        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
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        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45623:SF17">
        <property type="entry name" value="CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45623">
        <property type="entry name" value="CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Chromo_MIT1"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MYG1_exonuc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="3"/>
    </dbReference>
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        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="11">
        <location>
            <begin position="675"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="12">
        <location>
            <begin position="981"/>
            <end position="1133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="63"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
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            <end position="495"/>
        </location>
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        </location>
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        <location>
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        </location>
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        <location>
            <begin position="1921"/>
            <end position="1984"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="63"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="195"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="325"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
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        </location>
    </feature>
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        <location>
            <begin position="362"/>
            <end position="372"/>
        </location>
    </feature>
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        <location>
            <begin position="483"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
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        </location>
    </feature>
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        </location>
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        </location>
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            <end position="1817"/>
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    </feature>
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        <location>
            <begin position="1852"/>
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        </location>
    </feature>
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        <location>
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        </location>
    </feature>
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        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1946"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
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    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="KAG0019675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="2350" mass="261870" checksum="6448EBA7DF1FDF91" modified="2023-09-13" version="1">MESTDTTSMDRSSTSRGEVLKILDQTIHDGGAVKYTVLWENGDTTEESVEALGKWDDLVQEYEHSQFSKSEVKSHTPSPPPSRKSQQSSVKSDSDASKRGQPAASRPARTKARANVQYYEPEDSDDAAEYSGPRPNKRTSSKAKKPASSGDDAQDQDQETTPTPALSARGYTRRAQATIKPQPSLDSSEDSSDEVAPKAKSERKAPSAPKPKKTLVATSTESGFVQAHHPFCTRCGQRGEIAKRKSKKKSDDEDDDEPLGSLLLCECCSAGYHRLCLRKTYTDSLIGTGFRCESCIKNKGAECLECHEWVGRVPTATVAKVPDTAESSSSNGQSLGEDPSADITSESKQSLKETSSVPNSESSKDMDIEKDTTVATSPSKSEDSLEPAQEADAILFRCFRCTYTAHDKCLKPPSSMDNQVDRAQIVKYYRKEWKCHQCLEWDRELDQILAFRDVPIRKNGSSTLDGDTEMVPAGSTKSEETSTESSTKDGSTFPQASNTTRELLVKWKNMSYRKVTWVPSYWVSQVVSSVKIKSFWRKIQGPAGVSDVVLPQWTQVEKILDVVFDADYDGAEDDMDALDHIQSVFVKWKGLDYDQATWDEPDEPDSPDYSSFKQSFKDWVAAQKIEIPVRAKKGRSGLQPRPSNQLPFDELKEQPSYISGGTLKDYQMDGLNWLRYNHWKNVNSILADEMGLGKTIQMVAFVTTLFHQLRAFPCLIVVPNSTLTNWVREFAKWAPDLRVVAYYGPQTSRSVVRDYELFHRGTQDLKCHVVVTTYEMIVNPVDSALFRKNSWECLVVDEGQRLKNENSMLFVKLNELAVENRVLLTGTPLQNNIRELFSLMNFLDPVKFSDVTELEKKYENLDKNAVEELHGLLKPFFLRRTKDEVLKDLPPKSEVIVPVGMSALQKEIYKGILARNHKLLQSITNRGGTSSNRKASLHNILMELRKCLNHPYLIDGVEPRYLETAELVHKSLIEAGGKLELLHNMLPKLKQNGHRVLIFSTMTRLLDILEDYLNGEHYNFVRLDGSTSSSDRQARIDRFNAPNSDVFVFLLSTRAGGVGVNLATADTIIIYDVDFNPKADMQALSRAHRIGQKNKVLVLKFMTRNSAEERIVQIGKKKMILDHLIVERMEDDNLDPVDVESILKFGAKALFEEDSNTNEDLKYDDAALDALLDRSKIEHNWDENDNGETKVSGFGFAKVWTETKGLVDEDIPIDAPPETEEEGFWSTLLRDRLAMAYAQEEELLGRGARRKTVLSYAENGNNNESPPNKKRKAGKEAPSKEEEDYVDQDIGGSDVDSGESDPDVDPSSIMGELDLGKRAKKSRVPLDPNQLQSGEMELVMDEDGRQGSDAFGPQDGSNPLLGHGGKVKKARMQPASPYQMQGAVSTSGGRAMSAIDAANRKTGRKPQPCLVCHRSHRDRCPESQDIPLVLERRQQIATSNYPDNYKNLALATLDRFLLDKQITPAELPKGKTAKNLTAAAARLGGAAYQDSLRSMSIGKAFVPTITPGACIVCNQGPYHLPFNCPESRNIQFMQERCRSITLDPTIPDVKKQEYVSNIKGLISRESPRSNPPPAAAAPNSRRHGAWGTAGNSTSGHSASSRNVPTSAAASVILAAAQASGGQLNTSSKHTSSGQRSSHGHHSHSQHQAYTSPIPPQFMSSRPKEQQHQGSVPASVATQGSGRSDVQRRDYGPPSYHPRNTPQHHSSSSHMTSGARESSNYQPRKPSYRNDDGSIVAPPGRGSGYSNTSSRGGQEYVHDSSQGNDTLYGQERDRVGYGRPEGSRHELHLERERTYTHHEERGDDMSRAQQEYSRTDNGSYSSSHDRVSRHHSTQASSHYQEHSNHPSQHYRHNQQAPSQHQHQLQQQQQHGHASSRPRTVSMSPRDEHRVIGQQSRPSSQYTMDRHGSHPQQEAVVDLVMSSPKLDSSPPSMQQQSRRLQNEENEHVQTMITSPGASPQMDRGNSALSERHAKMEAPEASPTYGQGGFVAAARETDHADTTATSKLSSGAYGVGLKEKYHPMRAGEPTKMDLTAEREEDMAPELIGTHNGHFHCDEALAVHMLHQTKEFKNAGKITRTAGWEHIMSEAIEKKRSWAHHFFTEVFGGKFETKLSSAGLVYKHFGKEIMASILSLEESDSRVDLLYNKVYENFIEALDGGDNGISQYPADIKPKYRVGTALPQRVAGLNPWWNQENVDVDAQFMKAVAMTGEDFVSSVKYLGLSWLPARDLVVKALDQRLDIHPSGKILVFDRSCPWKEHLFNLEKELCIKEEALYVLYPDDNGQWRVQCVPPSPDSFECRKALPQAWRGFRDDELSERSGVPNSVFVHMGGFIGGNKTKEGALEMAVKSLEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2H4</accession>
    <name>A0A9P6T2H4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005157</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000256">
        <property type="protein sequence ID" value="KAG0019870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2H4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019176">
        <property type="entry name" value="Cytochrome_B561-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21780">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 209"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21780:SF0">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 209"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09786">
        <property type="entry name" value="CytochromB561_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="320"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="382"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="523"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="299"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="341"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="400"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="460"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0019870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1233" mass="135918" checksum="BA62E7D8EFFABEFE" modified="2023-09-13" version="1">MAEQAPSRLSKSRLNHEADEEEETFLREPAPVPPPEDFFKAPAKSFDINSIPHHKDEFGIAIRKQQNDELGEDNEEEQSLQSSLPGSLKVHPFASAIQTNRTRSESSVQGEQEVENDLVGMRHQFPGSLIDPSFRGDQIGAVNTIRKSTNWNTQSSTRGDATLETTEDIYPNIQKDQSSNEHLNSNGVQQEATTSTSLFPRTQDDQRLVLSGPLGSIPYQEPNDEEEDIMAPLPPLSEISIMPPLRDETGLPFSSTVAAESTFLENANLQRWDLFDNSQSDVYLDDGFIFPRNQGSRSLETHDTKHDANSRISPFAAYISSDSQKEVESSGKPNGGLEATSNRDVDRRDDGTGDDKVDVAHILETLAGAAASSELMKKFLDKDSGDETNSTGNAEEVGQPQPSSQKKVTPSSGSALDNHSSSEDGLTFDEGAGVGVGFKPIQETHPVHESIESDSMESEPLSRRFTAAEKGKQVDRDSLPTAEIRDRSVHDFPLIGSINDSDLNEIKEIGGAIFSMLKPSDISKPTAVSPRVSQSEELRTQIYPTAPPEPWASKPLDNRLSQRRPPSATTRTEVSEHDPNLGFMSSARKHTPVVQPAPTGTKSLLSDYPDAASKSATVAQPTVTLPSDPSKAPVLRGHYELPSIKKIDQWKSKHSLAPNSFRRLLINIGALIASNIIMKARIYRSVVTFLSSLLSPLVFYWIEWAVLLLLLFNIAEVIYSYTQSTNNFENLPLTPSQRSLLGLDPIVSKVPGAVPVFKKSATLPHNLAERPIMSTYVSPSHGAFTPTKPSFQKASVASAGLEYKDATIILNKSMSRSFNQSAVQDKADLSRLMRNIEAREELQAEWKSSDADPAKRPFGLHGSFGAPQGSLQTGVDMSVPDLLASVNSRGPVNRYQPALRTTLSKDHTSKTDLQKDGLYVVGYGKVLKNLKVSEHQLDRWAFNLRKWLWNKVVKHVCSEMEIVDAELARQGLSYLDCKSATMFYASVPLPQNTVNGTSSTAAAAPTAPAPLSSSLAWGAASIANTRLPSAFATTQPQQPQLPTSLQDLEARYGESRIVKQRIYLESYLAVPGYANRKYVVERLQAMGPLLTHFIWDSHGVTWDGGKKTWSPDLPSDSQIIMHLFMTYIDSAMPSHPSQVYDRFPFTYKHYVPVDNKPDPTTALQIKQTSKSPPNYSLVVEGSMWEVVPKRLNVWYTMVLFIYMVMKENSGYIGQINIGTQMIGLGDVVEGYDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2J0</accession>
    <name>A0A9P6T2J0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">HotDog ACOT-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_005027</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the acyl coenzyme A hydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000250">
        <property type="protein sequence ID" value="KAG0019949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2J0"/>
    <dbReference type="OrthoDB" id="331699at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047617">
        <property type="term" value="F:fatty acyl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006637">
        <property type="term" value="P:acyl-CoA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03442">
        <property type="entry name" value="BFIT_BACH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033120">
        <property type="entry name" value="HOTDOG_ACOT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12655">
        <property type="entry name" value="ACYL-COA THIOESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12655:SF0">
        <property type="entry name" value="ACYL-COENZYME A THIOESTERASE 9, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51770">
        <property type="entry name" value="HOTDOG_ACOT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="HotDog ACOT-type" evidence="6">
        <location>
            <begin position="149"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="52"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0019949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="256" mass="28104" checksum="F799E2FEFAEDEC11" modified="2023-09-13" version="1">MQRFSCPSSSSISSSLTRVSRSRSTGVVRSKAVIASVLWRDFNRNNTLYFSTSTSHARQDDKKPGSNDMLDEIGTSMHNKSKPTIITAAGIDPSSMSASAASTASAEGNKVFTVRPVTSWIDKLAQMHGSPTLSADPIKKYEKRDLILKTMHDSYTEIILPFAKDKALLEEYINFGGHVRHGKIMEDLDALAGAISYKHCDDGKTNSQPIIIVTAAVDRIDFLRPFGVRDLRLSGHVTFVGYSSMEGKEGPLFLQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T456</accession>
    <name>A0A9P6T456_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_009807</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. NIM1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000062">
        <property type="protein sequence ID" value="KAG0023313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T456"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14081">
        <property type="entry name" value="STKc_BRSK1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000956">
        <property type="entry name" value="CAMK family protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000003">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF82">
        <property type="entry name" value="KP78A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="1"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="348"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="622"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="807"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="871"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="936"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="365"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="383"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="434"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="461"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="630"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="811"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="839"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="936"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0023313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="959" mass="104702" checksum="711B4B7B70162A2D" modified="2023-09-13" version="1">MLGKTLGKGSSGCVKLARHRKTNEQVAVKIISKASLANRAAVHRGIEREIAIMKLINHPHVIRLYDVYETDKELFLVMEYVSGGELFEYLVNKGRLEETEALRFFQQIIVGLAFCHKRKICHRDLKPENLLLDDQRNVKIADFGMASLQKSGRLLETSCGSPHYASPEVVTGMKYDGSSSDIWSCGIILYALLTGHLPFDDENIRQLLSKVKAGKFYMPPDISTDARDLITRMLTVDPKRRITMQGVMSHSWFRMVDPECNTLGEPAQDPENGQPMLTEELDAEILRHMRWLFAPGPSHSHPEAKEVFDEEALLLEIQEKMTSNDENMEKLFYHLLCQHKTELLENYSGDESDIDPDAPRRRTDSFPNSAGSVRSATPEFGRTSLSPRDSPITSPKSLSPTAKGVEPTPLSLNPEPIIASSTHSGYTNELREGQSPSKLNGIISNKDTQTPCSEEAQGDSLLKKDDSERCDDGVKDENKAIMSRRVSPSNGSMHEGFNNQVATTKAEKVHQSTITISDPMAQPPPVYPAETINATNPVSSVANEAKRSSALVNSEIAAATAPSIESQVLSTQISEINNNTTSAHSTQAALRSQPIEGDIVVSPNASSTEKLRFETLTTLSQKPTFHPSEVKTTAGTVATNASASQHSRKHSEGASSVISSTALSPKRHWFARLFDFKPQPLAFKSSVSASEAQERVEVILQSLFTSSIHIDSHRKSSSGVKCRFDGGVIGDQIARPVKFKVDISEKPGLLQSSTSTLGRTNSSRNVSSSAVTTLLAAADPNNSSATSNNSTKYNSANSNINVEIFKHEASDSSSSSSPSSSTENVIVEGGGEAPTGKKKSSEDLPNRRASDGGSILSAFTSHFAAKFSFTNHSNHSSSSKHRHSVHGMTPNSGRPPTPQMQPIRIVKITLHQQQGANSTLKMIFEQLCAAWDQPFDQQQQNPEPQVQQAPVATPMTAVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T476</accession>
    <name>A0A9P6T476_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">60S ribosomal protein L35</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RPL35_1</name>
        <name evidence="6" type="ORF">BGZ80_007279</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL29 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000037">
        <property type="protein sequence ID" value="KAG0023917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T476"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
        <property type="term" value="P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00427">
        <property type="entry name" value="Ribosomal_L29_HIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.310:FF:000002">
        <property type="entry name" value="60S ribosomal protein L35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="6.10.250.3450:FF:000001">
        <property type="entry name" value="60S ribosomal protein L35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00374">
        <property type="entry name" value="Ribosomal_uL29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001854">
        <property type="entry name" value="Ribosomal_uL29"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018254">
        <property type="entry name" value="Ribosomal_uL29_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045059">
        <property type="entry name" value="Ribosomal_uL29_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036049">
        <property type="entry name" value="Ribosomal_uL29_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00012">
        <property type="entry name" value="L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45722">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45722:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL29-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00831">
        <property type="entry name" value="Ribosomal_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46561">
        <property type="entry name" value="Ribosomal protein L29 (L29p)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00579">
        <property type="entry name" value="RIBOSOMAL_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="41"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="71"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0023917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="187" mass="20476" checksum="7207195808D9B819" modified="2023-09-13" version="1">MDAGQETRKPNLIANYGDVAGMYQIQVAIIDADNAIVGVNVVVGVVGVIGAVGTAIVGIAVAAGEAAVKAHELRTKNKAELTKQLEELKQELSSLKVQKVAGGSASKLTRISAVRKSIARVMTVITQTQRSQLRLFYQKKNFLPLDLRVKKTRAIRRRLTKNESSIKTLKQQKKDTHFPLRKYAIKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T4D4</accession>
    <name>A0A9P6T4D4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_005246</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000026">
        <property type="protein sequence ID" value="KAG0024208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T4D4"/>
    <dbReference type="OrthoDB" id="2210at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009069">
        <property type="entry name" value="Cys_alpha_HP_mot_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017264">
        <property type="entry name" value="Ribosomal_mS37_fun"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28066">
        <property type="entry name" value="37S RIBOSOMAL PROTEIN MRP10, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28066:SF1">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN MS37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47072">
        <property type="entry name" value="Cysteine alpha-hairpin motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0024208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="88" mass="9926" checksum="B194F8DA1EB855C1" modified="2023-09-13" version="1">MLFSYSPTKGSVNMRLKYLRTKPRKVIEASPCIAEMGAMIQCWTASGVDDAKCMQTAKMLADCMKNLPTKVKKVNTVNYHLARLQKQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T4D8</accession>
    <name>A0A9P6T4D8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006087</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000030">
        <property type="protein sequence ID" value="KAG0024078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T4D8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019956">
        <property type="entry name" value="Ubiquitin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050158">
        <property type="entry name" value="Ubiquitin_ubiquitin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10666">
        <property type="entry name" value="UBIQUITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00348">
        <property type="entry name" value="UBIQUITIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="1">
        <location>
            <begin position="77"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0024078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="351" mass="39655" checksum="E600306EA82E7083" modified="2023-09-13" version="1">MPATLDILIASEPGKSVSIPYKAEEPIFFLIQRISNQLGENTNNSLWRRLYVNGMYIEEEQQSIENYRIFGNVFTYLSSGNNGIPPDQQRFVFAGVQLKEHRTFQDYRIAKESVIHLILRLEGGGAVLPSVTFSDVSDAAGVRKYEFSDSAPPGRVVYPGTNIECSCECTKGYRVICPKYRGVIELSKERFTCPNCDESSRIVPVTVGFSECKYRFHGIKANGEQYTSDWKEVKPEDCYQLFSPGNQITWKRLVIESAGLEDCGDFWEHLFRLTQVVLHHAPIPITEMSLSPADDPVPEQFGVGQWMHYIIGDQNNQVQVKTLSAFHDFIAEIRSGLSDDDCEAQICKGSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T4N1</accession>
    <name>A0A9P6T4N1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_002056</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000015">
        <property type="protein sequence ID" value="KAG0024496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T4N1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="2">
        <location>
            <begin position="19"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="2">
        <location>
            <begin position="55"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0024496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="84" mass="9461" checksum="81337DC3F6A375FC" modified="2023-09-13" version="1">MVVINTALLAKKFPQLPANDVDNLVNQFRRFDIDGRGQIDQKDLVKVIQEIGEGDSYDQIRATIKTVDINATGKVEVDEFLEVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T4Q9</accession>
    <name>A0A9P6T4Q9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Nucleoside transporter family</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_009009</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000051">
        <property type="protein sequence ID" value="KAG0023576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T4Q9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005337">
        <property type="term" value="F:nucleoside transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002259">
        <property type="entry name" value="Eqnu_transpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10332">
        <property type="entry name" value="EQUILIBRATIVE NUCLEOSIDE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10332:SF88">
        <property type="entry name" value="EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01733">
        <property type="entry name" value="Nucleoside_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016379">
        <property type="entry name" value="ENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="179"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="321"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="357"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="401"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="438"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="478"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0023576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="508" mass="55562" checksum="6F1EA344C3C940F4" modified="2023-09-13" version="1">MPASADETTPLCSEIAPNNSLHLEVPPIDNDDDADDLETHSLLRHTTVEDEPPSDPWHLSYWIMVLQGASMLLPWNVFITAQGFFKLKFTGSPFENNFQNYFSVAFMGTNLLVVGGSILIQKKGLAGAGVAISQIVTQILSPPKGSTYKEDYLSVSSLAGRGDFNGGRKGKSEGLEHSAFLFFSFALAFTVISVLAQALLIRLPIYEYYTLDRPCQPIEFLAPPSTTSDSHAVDEAVEGVLNSTHGRRNSDSSAVTTVTITPAMIAEANRRHAEEAAEREAAERVSHYRSTSLGATVLATDASAEQLMEEIYPKKKHHPLVILYITITLVFGLTLSLFPSLTALVESTNTDPKRPRIFGDLFVPLHFLIYNVGDWSGRTLPSISYFTPNTRHPTRKQQVRYLLSALGRLAFIPIFLTANLPIPQDKRLLPFLIQNDAVWFLLLFLFALSNGYIGSIVMMVGPSCVLGGENKSRAGVKLGFWLTTGLALGSVASFGVRQLMCAKGGCSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T4W9</accession>
    <name>A0A9P6T4W9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Era Like 12S Mitochondrial RRNA Chaperone 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ERAL1</name>
        <name evidence="8" type="ORF">BGZ80_010280</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000007">
        <property type="protein sequence ID" value="KAG0024701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T4W9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043024">
        <property type="term" value="F:ribosomal small subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000028">
        <property type="term" value="P:ribosomal small subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04163">
        <property type="entry name" value="Era"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22534">
        <property type="entry name" value="KH-II_Era"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00367">
        <property type="entry name" value="GTPase_Era"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030388">
        <property type="entry name" value="G_ERA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005662">
        <property type="entry name" value="GTPase_Era-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004044">
        <property type="entry name" value="KH_dom_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00436">
        <property type="entry name" value="era"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42698">
        <property type="entry name" value="GTPASE ERA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42698:SF1">
        <property type="entry name" value="GTPASE ERA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07650">
        <property type="entry name" value="KH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="Prokaryotic type KH domain (KH-domain type II)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="G" evidence="6">
        <location>
            <begin position="126"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="KH type-2" evidence="7">
        <location>
            <begin position="347"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="46"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="10"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="64"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0024701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="408" mass="45803" checksum="823043082944C04E" modified="2023-09-13" version="1">MSHSIPLIRATQTNKSSPGEDTTTPTSKSLELLKKTLYEKRKKLQEITERQASQESVAAAGSISGPTSTTPQSPALTKHEATPTSMDQRSVPDRSMPVFASPADMTVRLPKVVRNFNQPENAEIAKIAIIGSPNVGKSTIVNDLVKSTVSIVSIRPHTTRERIKAIMTHENKQLVFYDTPGVVPEKNISRLNRELVTASWKAINDADHLLVVMDCNKLLEHTLVTESYIFQRLKELENKVPATLVFNKMDLVKGRDEKLQEFVREYNQQYPAFIKTIFTSAETPKVGIQELRSHLLSLTQPGPWLYPANQKSEQSDLSRVEDMIRSEIYAILKVPYNVKQVNVGWTELVDNVLRIDQNLIVDRPGLKKILVGTDGSVIRDLTLNARQLIGKALQRRVLLNLQVKVKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MCW1</accession>
    <name>A0A9P6MCW1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008405</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004540">
        <property type="protein sequence ID" value="KAF9992801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MCW1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9992801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="147" mass="16644" checksum="B44F3AB7F842BE4D" modified="2023-09-13" version="1" fragment="single">KDTVKRPGTKSTPSNNNKRRKGSSSKPTTEPTIALDPYMNPQMQSRVKRYNELDQHGFWRLARGRAVETVLFECSLKGRASFKSLFTDLEWAEISQFNKFDLPALPRSTVEYIKEVQSALVSGKHAVSVPVPEIRFSCDQILKSLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MD24</accession>
    <name>A0A9P6MD24_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_008398</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004537">
        <property type="protein sequence ID" value="KAF9992810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MD24"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9992810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="94" mass="10543" checksum="37D419591C0C86FB" modified="2023-09-13" version="1">MFGETLAKEEPEVTTVSIRPGVVDTEMQSAIRTKGVGNMVPDQHAKFVNYHTSKELLHPDEPGHVIASLSVKAPNSINGRFFSWNDEELKEHRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MD51</accession>
    <name>A0A9P6MD51_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Micro-fibrillar-associated protein 1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_008447</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004580">
        <property type="protein sequence ID" value="KAF9992699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MD51"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033194">
        <property type="entry name" value="MFAP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009730">
        <property type="entry name" value="MFAP1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15327">
        <property type="entry name" value="MICROFIBRIL-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06991">
        <property type="entry name" value="MFAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Micro-fibrillar-associated protein 1 C-terminal" evidence="2">
        <location>
            <begin position="16"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9992699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="180" mass="20928" checksum="65C74B3D1AEBD7D5" modified="2023-09-13" version="1" fragment="single">DSEGSSEYTSGSEESSEDELAPRRKLMKPVFVPKSQRITIDETTNPDVAAELAEKARLEAIEERKKESHQMLKEYVARQANVEEVPDVDNLAEVDDTDGIDEEAEFEQWKLRELKRIKRDREELEAREAEKAEIERRRELTEEERVKEDMEYLAKKAKEEAASKASVPIEKYHHKGAFFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MD95</accession>
    <name>A0A9P6MD95_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008276</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004437">
        <property type="protein sequence ID" value="KAF9993099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MD95"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9993099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="154" mass="17036" checksum="4BC8841AC0E155D4" modified="2023-09-13" version="1" fragment="single">ETVVVLAGYKNEELTADSCDIDQAINILAKQTSNGALLELYGMGIEPNRTDVPSHTPSGELLTRVPSKASTTSTLHASESESKFSPDKKFKTAQPEYSQSGELPADEYEMVVHTWNSTDRPYPSDRCIHELFEEQVVETPDAVALVHESRSMTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MDF6</accession>
    <name>A0A9P6MDF6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PAS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008206</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004383">
        <property type="protein sequence ID" value="KAF9993271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MDF6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAS" evidence="1">
        <location>
            <begin position="13"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9993271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="226" mass="26023" checksum="B1ECB4A375E732A5" modified="2023-09-13" version="1" fragment="single">MFYDNNFLAFHDLSAAGLFLWASSSVTHFLQYDPSEIVGMSPFSLIHPDDLEACRVTHKEHVLNEIVGTHMSFRLRRKDGSYAPCMIFGCLCYQYIISCYSFEEEVNERPRKPIVHGVHSAVMTRIVGSEKEEFERISRNHNTLKSDTWNPANLQLELRACLLLNRFSRNITIMYASPSCELIFNIDPDELLGKPLLLYIRADDLGNFVDQVDQVKSSTALRHIRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MDN6</accession>
    <name>A0A9P6MDN6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007942</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004175">
        <property type="protein sequence ID" value="KAF9994023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MDN6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9994023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="156" mass="17281" checksum="AB58F0BD46BE8AC8" modified="2023-09-13" version="1" fragment="single">QRATIYEGRNSARNTKLMSSSSKKRDSAENVVSTKAKMVEQSQAPVAVVPTPPRINAKSSRRRAQSRQYDNVPSEAAIIAAAAAAAASNDDYLDTNRHEQNPDAYFETSMDNHGYGGGQTYGNQSENYYNHHHHHPHHPHHQARTAAATVNPEGYW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ME00</accession>
    <name>A0A9P6ME00_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007839</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004096">
        <property type="protein sequence ID" value="KAF9994333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ME00"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009247">
        <property type="term" value="P:glycolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051276">
        <property type="entry name" value="Saccharopine_DH-like_oxidrdct"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12286">
        <property type="entry name" value="SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12286:SF5">
        <property type="entry name" value="SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9994333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="177" mass="18791" checksum="583FA1CE0B93932A" modified="2023-09-13" version="1" fragment="single">MSSANEKIVKRSHGLKFESDGVGYGPQFTYRESMSTPGFLSATITTIGLAIGGAALSVGPLRRFIQKRFLPAPGTGPTDESIAKGHFTIKVVGESGAPENAPSGRAKAGHQKPTRVMAVIQGGDPGYSETCRYLAEGALCIVQNEDRIRSENKIKGGVLTPAFAFGDILIERLRAQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ME61</accession>
    <name>A0A9P6ME61_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007664</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003969">
        <property type="protein sequence ID" value="KAF9994874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ME61"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9994874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="107" mass="11026" checksum="95BB5DA69D228370" modified="2023-09-13" version="1">MACAVTEVEGDALLSVGSIEKKKRSADEVGGFDGTDVDADIEGAAATGLLDVDADVDVDVNVDTDADADADVDVVGTNATDDVDNDADLREEDVGIDQDESPVRVLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ME86</accession>
    <name>A0A9P6ME86_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007777</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004037">
        <property type="protein sequence ID" value="KAF9994565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ME86"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9994565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="82" mass="8172" checksum="5D74C7B55917E8C6" modified="2023-09-13" version="1" fragment="single">SDRVVMIESALQHHVVDVATAPAAPADLAHPAAPADHADLADLDDSADLADSVGPADPVDPVDPAAPASPITVLLGSHSARI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MEZ6</accession>
    <name>A0A9P6MEZ6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007393</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003774">
        <property type="protein sequence ID" value="KAF9995901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MEZ6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9995901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="194" mass="20882" checksum="7BE0D70886DD5382" modified="2023-09-13" version="1">MGNALCHSKTDGASGPVNGSVALSNGSEKKVIQKTQRNRTASTTSATKGKSKISKIKTKDSHPAQSSLFSSSSTTDFSESNPSPVLTANQTEQRLASLPQRNESVAQSLGSGTGSSGIVFSRSPEGSNDTTLINHQIFNNNRNSTIASSDNNTSYSLEKMHERNQVSIEYQWLEGRRYHNTPGASYLLPNDIDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MF29</accession>
    <name>A0A9P6MF29_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007304</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003710">
        <property type="protein sequence ID" value="KAF9996261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MF29"/>
    <dbReference type="OrthoDB" id="3210850at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38848">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 3 PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38848:SF3">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 3 PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="178"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="204"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9996261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="289" mass="32279" checksum="DDBC3895E09429AD" modified="2023-09-13" version="1">MSFLLGRKTSGMSISSLNYARGLVVALYITSWLFSFVVALLAQTNNNNWISCEASCFVCIFLYAASKVLIYLFMVERVHVVTDVGVTRWNSRIFKFNIALVAPFSVILALALKFRVAEIDDLGYCKIGLKTQSSVPLIAYDTLINVWLTFLFVRSLNSSTSKLQGSRANKLRTVARRTLIGAILSLILSSANITTFVIFNGHETGALCLALCTLDVTLNAVTIHWVTSPRRSPKISVKSTPKRDWPSKVDSVTVERQEVSPLRSHFSISIESYVEEYHPAHGPSREYNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MG31</accession>
    <name>A0A9P6MG31_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006794</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003375">
        <property type="protein sequence ID" value="KAF9998388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MG31"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9998388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="212" mass="23983" checksum="E39788C7B1F991AC" modified="2023-09-13" version="1" fragment="single">MIDGNSKNPSAHQQHDGQDEKKTKKLKPNQDNAGPSHDQGNNPTTTPVGGSVVGKAGGFVYKRDRGMQGLNEVEDEDMEDMEDSEDQNMVSNEWHQVQRAKDRCFSAVVPLDYLFGTTAREKKQELEELMINNYVHCTEGPTKIKMETGDPCFKFSVETKDELEKLLEIPMEIAHPDGIVEQVMMFTRVDNSRRVSELERTVEVYGLHPRTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MI05</accession>
    <name>A0A9P6MI05_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005974</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002944">
        <property type="protein sequence ID" value="KAG0002453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MI05"/>
    <dbReference type="OrthoDB" id="2445692at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0002453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="61" mass="6526" checksum="A6C1F6F73D782747" modified="2023-09-13" version="1" fragment="single">MSLFKSNKNKSASADSTPAQTPRTSMHEARPTKVNTMTFEDALQLTLSKSIPCGAKATGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MIM1</accession>
    <name>A0A9P6MIM1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Actin-like ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005801</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002857">
        <property type="protein sequence ID" value="KAG0003375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MIM1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10229">
        <property type="entry name" value="ASKHA_NBD_HSP70_HSPA12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187">
        <property type="entry name" value="ALPHA KINASE/ELONGATION FACTOR 2 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187:SF5">
        <property type="entry name" value="HEAT SHOCK 70 KDA PROTEIN 12A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="92"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0003375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="671" mass="73739" checksum="37D72A25DADE285C" modified="2023-09-13" version="1">MGSNMGNNMGNMGNNMGNNNMSNMGGGMGGGMGGSMGGGMGGGMGGGYDNNNSNGYDNNANGYDNNNNGGNNFNANQSYQAGALDYQRTIYNQPPSSQQSGPGMSPNSNASTATPIRAQAPQPEKEYPVVMAIDFGTTFSGVAYALKADGEVHDITKWPRHLAQYPKTPTLSLYKKDSQKILDWGHAARLAMLKPTARDFCLLRKFKLQLDETLHSAPLENGITALEAVTHYLKKLHGHVMSELMKGFIKNYEASQFQYCLTVPAMWSDSAKNTMRRAAIGAGLIQEGDPPNRLILISEPEAAAMYCERMVDRFSLKHGDRFMICDAGGGTVDLIVFEVSEPPGQARHLKEVTRGHGASCGSVFLDANMERLLERKFRRYRKGIKACGWASLMDTFVDMVKPMFNGQEDVLMQIPQATGLEDLNDPDIGLEEGVLCVPVEEMKEEVFEPVISDVLDLIQKQLHQSQSCNAIFMVGGFGSSRYLEERVRQEFSHLVGLIAVPQRPELAVVRGAVYAGLNTKTINMRVARRWYGVDANMPFEEGVDPESKKIISHDGHVRCKERFSVYVRPGQQIGVDECVSKEYVTWSYPKGLDSPLYVCNSPTQPKYITDPGVQKIADFHIPMPEIPGAQPRTRVVFRLNMYFGLTEVRAEAVINGNTYTTICSFGGGGSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MKJ6</accession>
    <name>A0A9P6MKJ6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005524</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002720">
        <property type="protein sequence ID" value="KAG0004989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MKJ6"/>
    <dbReference type="OrthoDB" id="17798at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="475"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="475"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="503"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0004989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="780" mass="87432" checksum="D142C09C651608D9" modified="2023-09-13" version="1">MATIAILGLTFDPKDASIGRAADRSFVVSSSSPAIIFHSSIKELKEVAINGSVLVTQQYFEKLEKTEYNAKQMANVRRYIRPGAEFMPLESYGAHVVLMNATPNPMKLHLELQLPQGSICIYNPIESGQDVQLAAHGTFQYEYHFYFPDEGDFPHYPAHISDYENIIAFANPSVLKVRKPEKGQAKDTADFTSWSHVIARGTQEEVLEKLKSDPLESIRVELLMPRLYRDKNFLKLVTDVLRGRHEYNDRIWSVSLMIKETEEKEVLNLVSEYLANKPIVQKLGYWFTSTLVTRKPRNRYETARGVFHYLEYFPLINARVHKANKNVTILNDRFKEQYIRFLTLLSQKPKHDVEDLLVLTVYLLAQDRILEAKEQFVKLSALVKEGHLDELNDSQEQRLEGEHTSFQAIQYDYLRAYLSLCVEVQVDNSNPNLVVDLDDIQAIANKYQNYPVQRWNKLFKDLKTYVDEILRTTSGRNKTSPAQSGANAEQGSDTAIATEKVPSESSTSGNSNKTASRKPVRATVDFKIGSDSEITIHHRGVEQIIVEYYAIDAETMFSASPLTFSDQGESEINVAANGAITAGAVEITNAKPAAFGGGSPVSDTTSYRLVKPNGVDKHTVEFSSDDAVLKVPILEKYLNTNVMISVLTSPPAATKTWKAFYSQTMSVLCQEGRGTIKVVTKPAANNDYESQPIRGGYVKVYAEMKSNRERVGQTLFWKDGYTDLVGRFNYAIVSTATGSPSKSLFNGSFSSSLMDVKRFVLFVDGGKEGCVVKTVPVPPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MKY2</accession>
    <name>A0A9P6MKY2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_005205</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002581">
        <property type="protein sequence ID" value="KAG0006621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MKY2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990189">
        <property type="term" value="F:protein N-terminal-serine acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008999">
        <property type="term" value="F:protein-N-terminal-alanine acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051908">
        <property type="entry name" value="Ribosomal_N-acetyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43441:SF2">
        <property type="entry name" value="FAMILY ACETYLTRANSFERASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G00850)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43441">
        <property type="entry name" value="RIBOSOMAL-PROTEIN-SERINE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="39"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="257"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0006621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="276" mass="31589" checksum="8F7309ECA1A0D90A" modified="2023-09-13" version="1">MTISKTISYTRLPSSEFSQSSLGVNNGTIIETGQVKLVPILLERDTPLLWEVYKDHPKLFDWMPHGPLHTYEEFFAIQARFCSSNDHFNWACYVSASSSNTNEKEKKWVLCGSICLLDISLIHRRFEVGGIWFHPSVQGTFVMLETTYALLRFSFERLIAGRVQWKTHHKNIASQKAAIKLGFDLDGIHRKHIIHSDGTWRNTYYYSMTDDDWFGKDVTTDGQPKLEVEKAIRALEQELLLSGAQGRQKRLEELIENRKQEGKPLPSAVVGGESLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MLX8</accession>
    <name>A0A9P6MLX8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Malonyl-CoA decarboxylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_004570</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002315">
        <property type="protein sequence ID" value="KAG0007520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MLX8"/>
    <dbReference type="OrthoDB" id="426718at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005782">
        <property type="term" value="C:peroxisomal matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050080">
        <property type="term" value="F:malonyl-CoA decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006085">
        <property type="term" value="P:acetyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001294">
        <property type="term" value="P:malonyl-CoA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.150">
        <property type="entry name" value="Malonyl-CoA decarboxylase, catalytic domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.90">
        <property type="entry name" value="Malonyl-CoA decarboxylase, oligemerization domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038917">
        <property type="entry name" value="Malonyl_CoA_deC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007956">
        <property type="entry name" value="Malonyl_CoA_deC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042303">
        <property type="entry name" value="Malonyl_CoA_deC_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035372">
        <property type="entry name" value="MCD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038351">
        <property type="entry name" value="MCD_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28641">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28641:SF1">
        <property type="entry name" value="MALONYL-COA DECARBOXYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05292">
        <property type="entry name" value="MCD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17408">
        <property type="entry name" value="MCD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Malonyl-CoA decarboxylase N-terminal" evidence="3">
        <location>
            <begin position="128"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="Malonyl-CoA decarboxylase C-terminal" evidence="2">
        <location>
            <begin position="224"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="Malonyl-CoA decarboxylase C-terminal" evidence="2">
        <location>
            <begin position="348"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="9"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0007520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="579" mass="64676" checksum="14A493D57978FDAB" modified="2023-09-13" version="1">MASTGGNNGSHNNDDSNNNSNFASMGGGGGGAGSGTLQALRPNVVDRYWNDIAEHFREPGFSTFDKEKSSMVTRDPEFMRKLLLAVITDRPGQGDILPSVIAKSSCDFFTSLDKTGKTEFLKLLAHDFGVLQEDVAKAARQYTDYSRLEPESKALLRAEQLLRHALIPGHNKFFDRVSRLPGGLKFLIDLRHDLIDILHENRGDFYLTALNDSLKEKLQNWFVGFLDLERLTWQSPAALLEKVTQYEAVHKFKDFNDLKRRVGPGRRVFALMNKSLPNEPLVFVQVALVETLSDNVQDILNDPSPGHKDPAKTIKCAIFYSITTQADHGFHDHHLGFSHHRGFFLGNTGLSGIELGNFLIKRVVRSLKVEFPQIETFSTLSPIPGFRKWMGQCQKLGQALLLPQENRIVAQLGENLLKNGGDADPEEQFNALLQHPSAFSDSETMGKLRPILSRLCARYLLLEKRRILALDPVANFHIRNGACVHRLNWLGDTSEKGMEESFGMMVNYLYSLDHIEMNNQQYLRDGTISVSSRDPAFESALASVKSQTQAVDEGGLGNDEGQLVQLNGVRLRLLEVTTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MM58</accession>
    <name>A0A9P6MM58_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NAD-dependent epimerase/dehydratase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004976</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002483">
        <property type="protein sequence ID" value="KAG0007183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MM58"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050177">
        <property type="entry name" value="Lipid_A_modif_metabolic_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43245">
        <property type="entry name" value="BIFUNCTIONAL POLYMYXIN RESISTANCE PROTEIN ARNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43245:SF11">
        <property type="entry name" value="LD23561P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="1">
        <location>
            <begin position="10"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0007183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="279" mass="31479" checksum="8503D4E886A3A6ED" modified="2023-09-13" version="1" fragment="single">IYEDRIYKLSINCAKEAVKKNAKVFVQLSTGDIYESTGTASKEDSKTKPWNEIAKYKLKVDEELQNMAGLNLVILRPAVVYGVGAMGGLTPRLICGRVYQHLKKKMEFLWTEDLRINTVHVHDVVRAVWHTANWYVSSDNPQQGSPVTFNLADENDTNQEAVNTHIRSIFGIETGFTGSVIAGLAQKLDLIDMKEVTEETNDMHLAPWAELLKKEDIKNSPLTPYLDQELLYNNALSLDGTKICVSTGFTYEHPKLTTESLREVITDFQELGIWPKDSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMA2</accession>
    <name>A0A9P6MMA2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_004262</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002192">
        <property type="protein sequence ID" value="KAG0007762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMA2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001080">
        <property type="term" value="P:nitrogen catabolite activation of transcription from RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903833">
        <property type="term" value="P:positive regulation of cellular response to amino acid starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12193">
        <property type="entry name" value="bZIP_GCN4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050946">
        <property type="entry name" value="AP-1_TF_bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11462">
        <property type="entry name" value="JUN TRANSCRIPTION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11462:SF35">
        <property type="entry name" value="TRANSCRIPTION FACTOR JRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07716">
        <property type="entry name" value="bZIP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BZIP" evidence="6">
        <location>
            <begin position="366"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="137"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="297"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="385"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0007762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="442" mass="47307" checksum="9ECB418003DFF122" modified="2023-09-13" version="1">MNMSHVNPVFGATERLLKSADSLDFALTNQDKKSASLTRQGLPDSGSLDSVFASTELSTSLFDDWLSGDLHQAGFTGYQDFSSDSDSSNGHSPVLSCRSESPAFGFDSIASDTDLIRSPGFEPTMASFPADSQGSSINLFGNNANGDNNSSNNNSGNSASTTPMLPLTPEAVQQAAAALNIPWSKALEQAVMAQSLLASLPLALPNLALQQQQSVAPQLAMLMPQLTGANNFMPTTATTTSTTTTATAAASLANLKLNHGASINIAHDNAMEISPPCTPISTIAPSLPLQAERAASTAPSTPRLSILSSTQTSLPVSGASTPTVKTMTYKSSYRSASLMKRNREVEEPPSVLDGKDLSEMDEVSLKRAKNTDAARRSRYKKMVRMEGLEQRVAELEVENSMFESKLNEVELERSLLADKDQMQQARIQELEAMLASIRERLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMH8</accession>
    <name>A0A9P6MMH8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Aspartate aminotransferase, cytoplasmic</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">AAT2_2</name>
        <name evidence="6" type="ORF">BGZ80_004563</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002312">
        <property type="protein sequence ID" value="KAG0007527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMH8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004069">
        <property type="term" value="F:L-aspartate:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006532">
        <property type="term" value="P:aspartate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000796">
        <property type="entry name" value="Asp_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11879">
        <property type="entry name" value="ASPARTATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11879:SF55">
        <property type="entry name" value="GLUTAMATE OXALOACETATE TRANSAMINASE 1, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0007527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="96" mass="10500" checksum="85C73038983F6345" modified="2023-09-13" version="1" fragment="single">MASVFENVPAAPADVIFALTADYKADTFADKVNLGVGAYRTEEGKPWVLPVVHKVNRTFQIRVFSLHIPDVVIVKRTDQPEAHGDPQGGGCYSVFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMW0</accession>
    <name>A0A9P6MMW0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_003748</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. NIM1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002006">
        <property type="protein sequence ID" value="KAG0008194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMW0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF82">
        <property type="entry name" value="KP78A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="23"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="282"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="282"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0008194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="312" mass="33607" checksum="BFB3BE764EDE8B9D" modified="2023-09-13" version="1">MSPSTQPCVTAPQLPLYIDNGRLVLHQILGVGAYGSVYRATDTQTGQTYAVKSLNKTGLDSRQRAFQIQEARLHGAVSGHPNIATLHRVIEEDECLHMILDCGSEGDLFYTITEREGFIGNSLAIKSIFNQIARAVMHCHSHGVYHRDLKPENIIMFGESVKLVDFGLATTNETSSDFGCGSTFYLSPECQGGYNEQVKSYDSAANDVWSLGVILINLVFGRNPWKQACLRDDTFAAYVANNDFLQTILPIRGGGGPTTVAAPIDAMAATAATAAVGDVKVSKADDKKATKPDDTLCGNGDKDSGIALRSLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MN41</accession>
    <name>A0A9P6MN41_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_003664</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001989">
        <property type="protein sequence ID" value="KAG0008237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MN41"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0008237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="169" mass="18912" checksum="AD527149C79C2BFE" modified="2023-09-13" version="1" fragment="single">MAYQRKFLATATEDNGVWIFADINGNGSHDLDNTKVRNTSSSRIEGHGPHNESRFQQHSLATGTAFNIKDNGIWLMQEWTCNGKVDLVYIKTRNTASKRAASGVLHGDLTDLYYIKTRNTESGMVKVHVVSASSGWKSRLFYATTSSVPEDNGQWLMVDFIHQKQSDLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MP23</accession>
    <name>A0A9P6MP23_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003267</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001858">
        <property type="protein sequence ID" value="KAG0008590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MP23"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0008590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="77" mass="8217" checksum="E4A8D2E7C6C506B3" modified="2023-09-13" version="1" fragment="single">MISHGDLPLDVVTIGIETVVQFEQGLQDTVWSAASRSSCKDVADIAATRSSAVGCLKKKNDDQDHYNGHGDGDNNIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MP77</accession>
    <name>A0A9P6MP77_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Glutathione S-transferase 3, mitochondrial</fullName>
            <ecNumber evidence="15">4.4.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="19">Glutathione peroxidase MGST3</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="20">LTC4 synthase MGST3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="primary">MGST3</name>
        <name evidence="22" type="ORF">BGZ80_002818</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>15-deoxy-Delta(12,14)-prostaglandin J2 + glutathione = 15-deoxy-Delta(12,14)-prostaglandin J2-S-(R)-glutathione</text>
            <dbReference type="Rhea" id="RHEA:75963"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:85236"/>
            <dbReference type="ChEBI" id="CHEBI:194498"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="17">
            <dbReference type="Rhea" id="RHEA:75964"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>leukotriene C4 = leukotriene A4 + glutathione</text>
            <dbReference type="Rhea" id="RHEA:17617"/>
            <dbReference type="ChEBI" id="CHEBI:57463"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:57973"/>
            <dbReference type="EC" id="4.4.1.20"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="16">
            <dbReference type="Rhea" id="RHEA:17619"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="14">Lipid metabolism; arachidonate metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="13">Lipid metabolism; leukotriene C4 biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.4.1.20" evidence="15"/>
    <dbReference type="EMBL" id="JAAAID010001712">
        <property type="protein sequence ID" value="KAG0009031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MP77"/>
    <dbReference type="OrthoDB" id="410651at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004602">
        <property type="term" value="F:glutathione peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004464">
        <property type="term" value="F:leukotriene-C4 synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.550:FF:000004">
        <property type="entry name" value="Microsomal glutathione S-transferase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.550">
        <property type="entry name" value="Membrane associated eicosanoid/glutathione metabolism-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050997">
        <property type="entry name" value="MAPEG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023352">
        <property type="entry name" value="MAPEG-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001129">
        <property type="entry name" value="Membr-assoc_MAPEG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10250:SF26">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10250">
        <property type="entry name" value="MICROSOMAL GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01124">
        <property type="entry name" value="MAPEG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161084">
        <property type="entry name" value="MAPEG domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="11" id="KW-0456">Lyase</keyword>
    <keyword evidence="9 21" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-0564">Palmitate</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 21" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 21" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="78"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00037884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00037916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00039056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00049298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00051411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00069748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00075145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00076908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAG0009031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="147" mass="15660" checksum="3952D6B2681ED116" modified="2023-09-13" version="1">MTTITIPAEYGYTLAVSVVSSILVTALGVKVGTYRKVAGVNLPQMYADDEEAKKDKKKMIFNCKQRVHQNTLEGFTTYMASLLIAGIQYPTAAAGLGLVWCAGRILYSMGYSSGDPAKRSWGGFGHIGGLGLLGLVGKMAYDLIVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPB8</accession>
    <name>A0A9P6MPB8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_002716</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001682">
        <property type="protein sequence ID" value="KAG0009123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPB8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="240"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="362"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="55"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="137"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="277"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="242"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="379"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="449"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="464"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="482"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="496"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="541"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0009123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="556" mass="61828" checksum="67B56C35F968890C" modified="2023-09-13" version="1" fragment="single">MEDPSDGCYCSQELACPHWIAAKMDSRLTTAKEHSHTRTKTFERELLQEDHRPVVSELQRELRSAMLEIEKLAKTSRDLAKINQELEESRLLAVSDQARTAKRLILVSSQLEHTEQQLFDLTKEVNIGQRDSELLRIERIKREALQEREDAGRLKIEALQDELQEVQRSERAMQQRLTAIQSKYESLSKRHDNLKKQQQELELARESKEALAWLKETTDRLCSPPQGSLGQAIQQERSSLGSGAISIHRSSPSSSPPYPSSFIDPPLAAQNQLISLIKELATTNSTLRSELNEYRDLLQDTRNEMLALRSQVEDYEQGHAFANCCGGRIDDGESFRTSRSAWSTLDIPAGGGLDAVSHIGTLGSIPGSPPPYMTTPKASSRHRSHHHSHTSGVRGSVFGELERLYSQSHQDSSAPVAPKRQGRDNSRKNKQRVLNVDEIPTPTQGDSLATTVSTSASTSEAGRGSTSVMSSARSPVNPTPSKLHDQYDLDKSSPNSTTSRGRRSMSMDAELDIPGSSTNSDEDNGRHHQGMDSFNPLSDAADSKEDQNELVDRFAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPH0</accession>
    <name>A0A9P6MPH0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003044</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001784">
        <property type="protein sequence ID" value="KAG0008797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPH0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="174"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0008797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="401" mass="44758" checksum="EA39B1D48B629576" modified="2023-09-13" version="1" fragment="single">MDTTNQSKDMEKSKRNDTETITRLDISWFEESHDKTPAAFFEHFGILKCDEGHLRYTRVLRQSTVNEQERTLLISKFEVWKNSEGCIFWERRNAKVVAEKSAWKTAGNLIEGSEPFAATIMAENAKEQRQRSALGNPAGSGQSSDGFLESTVQESEADGPTLDKELSSGLPVITSSSTQAASSTVGQQVNVPPSDLSDSQEHILTGETEESEIIDDQEKQNLIDSIENSKHEHDDCTWKIGDTCIACKFQVYQKSCIEALYNHELKKTEIADAMAVIGVFDPFNPTPRMASIISSEILEEISMQEPLDVLELDFNNIMKATQLAQNGNITGAIQAIYSSSLDTKTQIMIATLPNTDCETQKKQGVKPDRPDIALKVYDREAFFGEVTGPHLQSYNVKNQWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPQ2</accession>
    <name>A0A9P6MPQ2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FHA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_002882</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001734">
        <property type="protein sequence ID" value="KAG0008949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPQ2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051176">
        <property type="entry name" value="Cent_Immune-Sig_Mod"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15715">
        <property type="entry name" value="CENTROSOMAL PROTEIN OF 170 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15715:SF37">
        <property type="entry name" value="LD47843P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="436"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="domain" description="FHA" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="67"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="147"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="217"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="67"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="83"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0008949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="461" mass="51137" checksum="573F0CEC6F9627CF" modified="2023-09-13" version="1" fragment="single">VFIRDLKSSNGTFLNGKRLCPENVESEPFILNQNDHLEFGIDILDENGSLLHEKVACKVYISRMSSYPTPGGSPQESPTKLHSGSPTGSGPSSIRSNSVSAGQSTNIDLIISRLQNELTRSQETNADLGSLKQGLGELERTITVPVKEDEQSQVAEYQRLLEENNKIHAMEIAKLNRQLEETQSGLNAYVQKIQFLEPLVAEDEILKRDIAQSTAELSKVKLERDLAKDSLNELINEHQQTMNAFQKEQEAMMAALEANHKEALERMAREAALAQEIMIQKHQEDLAKALQSAAAPETESTLTSLKEKVDTLQETVENQTKLIQDLNTEKRTLSQALSETKAEVIKVEKKLEEVTLPTQEDLSSLTPASPSSTSFICKNPECRDKVAITKSVSRTSTAPGTSSRESKDLTTKLEFSWAQFVFPNSRKNSLQLNQPSTMLVSGGFMLVGIGAYAFWHKGSFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQC2</accession>
    <name>A0A9P6MQC2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">3'-5' exonuclease</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Werner Syndrome-like exonuclease</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BGZ80_001792</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001417">
        <property type="protein sequence ID" value="KAG0010096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQC2"/>
    <dbReference type="OrthoDB" id="1920326at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06141">
        <property type="entry name" value="WRN_exo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002562">
        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051132">
        <property type="entry name" value="3-5_Exonuclease_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13620:SF109">
        <property type="entry name" value="3'-5' EXONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13620">
        <property type="entry name" value="3-5 EXONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01612">
        <property type="entry name" value="DNA_pol_A_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00474">
        <property type="entry name" value="35EXOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3'-5' exonuclease" evidence="11">
        <location>
            <begin position="187"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="62"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="120"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="657"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="72"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="700"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="762"/>
            <end position="783"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00040531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00042761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0010096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="793" mass="88451" checksum="E4369142AF477C2F" modified="2023-09-13" version="1">MLRCKFGTAIVSRQTTAIPSPVLATRHYTLKSTQYHKQLAGSYRAPTTTARPPSFPFRCCRPSAPSSQHHATYTTTSETSSTFTSKTPDPSSVEAYVISDPSKTRKSQSKSAAVGHLLNSSHPKVARKSTRIRSTIDAKQHPPHSRIGSTSKPITQVHREQISETVQILIESMQEANVTLARDKPPVFLCSTYEQAEAAMELFTEYYKTLKGTPGPVGFDTETTTSFVPRKGSGVSLVQIATQDVCLMFQVFRITKNNTSPDLFPPRLKAFLEDPEQIKAGVASFGDASALRRSYGIECAGIVSLESMAREKEIIARSLASLDAMFGRPGREVVKTKAMLVWDWDKEDLDPKWVWYAAKDAFAGVAIYENMVNNVLKESYMPYEEQYPMEEREIADDIFEFLTQRMGGKGKRSTLGAVEKFITKEYPRFLRIYRPVERIGPSRKYVKMLLEGGRMRLIGGKKPTSFLSDSDIVELPGRSLSSMLVTPEGIDIISPYFNGKKLDPSTLSVKGISPYDKEFVAADQDLADMKLFLELSWVWDQPRRKSALYGIYWSSRLNAEKRKILQAAIEKETEEKGHENAIEKEIEEKGHEDAINAETSLDRRLLPKATLNRHEASQYWEPFMERLIQHGVIRERRGNIEMNPLIEEQCLERVPIPPYSPEHYPSRKQIRQDNSDGPSPPVESEDIPKGDESVPAVSTEGANISSTSLGIPPNDVESEPLPETPTSGVKEEVSARPSEIPSSGAEPVSLTDVPNPVAVEEVNSSLLDTLQSEPTKPLETTPSDPIKTEKESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQT0</accession>
    <name>A0A9P6MQT0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RlpA-like protein double-psi beta-barrel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_002191</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001532">
        <property type="protein sequence ID" value="KAG0009658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQT0"/>
    <dbReference type="OrthoDB" id="623670at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22191">
        <property type="entry name" value="DPBB_RlpA_EXP_N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051477">
        <property type="entry name" value="Expansin_CellWall"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009009">
        <property type="entry name" value="RlpA-like_DPBB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836:SF22">
        <property type="entry name" value="RLPA-LIKE PROTEIN DOUBLE-PSI BETA-BARREL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03330">
        <property type="entry name" value="DPBB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="Barwin-like endoglucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040317083" description="RlpA-like protein double-psi beta-barrel domain-containing protein" evidence="2">
        <location>
            <begin position="24"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="RlpA-like protein double-psi beta-barrel" evidence="3">
        <location>
            <begin position="90"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0009658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="170" mass="18930" checksum="624860BE7C034EC2" modified="2023-09-13" version="1">MKFAQLSVLIMAMVIAFVSLSEAKSSDEKKKQTVKFGKKISGHSTWFNGHDLKAVACYGDLENNSHVNAKDDWHIGAVHMDFYKSEKSVCFECVKITANKKNKKSATRSIVVRIIDDCAGCHPTQIDLTASAFKQLATLDDGVVYTEYEFVRCPSKGSLKWPKSPKPLSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MR77</accession>
    <name>A0A9P6MR77_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_001797</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Host cell</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001419">
        <property type="protein sequence ID" value="KAG0010084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MR77"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043657">
        <property type="term" value="C:host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045379">
        <property type="entry name" value="Crinkler_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052396">
        <property type="entry name" value="Meiotic_Drive_Suppr_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37171">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE YRZF-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37171:SF1">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE YRZF-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20147">
        <property type="entry name" value="Crinkler"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="424"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="355"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="355"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0010084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="588" mass="66110" checksum="2F2F3034C14BB411" modified="2023-09-13" version="1">MSRQETPETTSDSTMGTLLKIYCIVDGGTTAFPIDISSEQSVGDLREKICTPARFGNIAPEELTLWQTKIPDSGQAVILDDIESKVKLTLSSRKLSAVFPSGFEDETVYIVVEPPTQGEPVRLTTLVSEKTFVQYITDAITPFEGAEHSQASTTNRAYSVTPTSITPWNDFIGNVRNMQLAEEPLHDTPVFCDERRFSMEADIQEIFKRDFGSVKCLPPFAETFRCPGMDYGLPDLICLRHGGNVCNRESTLFPIEIKQPKDLNLNESLPDAATHQLISGCLTGPLDIVRQIFGYMYCNGFRYGILSTFNQTWFIVRREDDPNSILVSPSISFNDTSPTMLSCYLWFIREAESDEKPKLDPPEENAVKKTLRSEKKIEARRRKRSKGSLAKRLAAAVLPRSLSGGRRSSARSHSASSVDFVPAFKDMKPITFSNRARTFKALWRGEVVFVKKCDIWNERPFIDELQNEIEIYSVLRELQGIWIPEMKLEGIMNGFEIVLVTEYVGDNINNEHLNSSDCDKIRRALAAIHNIGILHGDIKPDNIVVKRDGVNSRFMIIDFGLSTFTLDKGILDCEQKELDSMLAALSQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRC7</accession>
    <name>A0A9P6MRC7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001225</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001277">
        <property type="protein sequence ID" value="KAG0010727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRC7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0010727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="240" mass="26839" checksum="20B2D8E8EF65ECF7" modified="2023-09-13" version="1">MRGRGLEKYEDVVGSNADRIDSPRSFEQSSHAEALKEFSGSQKKGQVEEKTENDEWGNNKEEKGSEEIKQPEPKVLTMQTTALSMYRNGRLATPVASPVTMSHDPAEEAQSPTKDDDSLKNPIVCSSDYGHQDGHDTKEHEDQKDDSDGWDDPVDEDEEDFKRPRVIGMKDSNVTVSPTKVEESLEKKLGDMTFGDKLSRGHGLSESRDTIADKDKTVDEDEWDTTPSGDFNRREIVAGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRD9</accession>
    <name>A0A9P6MRD9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Squamous cell carcinoma antigen recognized by T-cells 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">SART3</name>
        <name evidence="7" type="ORF">BGZ80_001134</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001253">
        <property type="protein sequence ID" value="KAG0010861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRD9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003107">
        <property type="entry name" value="HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17204">
        <property type="entry name" value="PRE-MRNA PROCESSING PROTEIN PRP39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17204:SF25">
        <property type="entry name" value="RRM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23240">
        <property type="entry name" value="HAT_PRP39_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00386">
        <property type="entry name" value="HAT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="453"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0010861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="483" mass="55262" checksum="62140DC8B7754E66" modified="2023-09-13" version="1">MGKKDEFSDSEDDFEMDEIAASEDAISPETLELISTLKKSLEENSNQYEQHTQLISLLKASEKLQELREARESMSKSFPLSEELWMEWIKDESNMATSKDEKIHVLELYERATSDYLSITIWESYLEYAIQEYTESMDLPEIEVVVNGEYLNSLFQKAKKFTGYHTSQSHVVWNIWIDFELGKLASQEVPSAEDVDRVKEIYLERIAIPHSELEDTFSGFSSFISKYCGQDYEESMVQSNKIVNATRELLENLVPFEEHLETYLKPEGEVNGVLAKALNDLASVPNPQELSKVLLASCSYKFRRSADQGEAGGDPYCKLERLWIELESTVLGDHEQARKLWKSIETKQMSMSDFWIARAEMEKKFDNVKGARQIFVRACSTAETLDWPEKIFDSWLLFERECGTLQTYKDALIRTRVALKNVEAVRTQAYASQVASDAIQQAEITAAVAADNVPKAGSKKRKLSVQDENNVSKIPKTKDDQKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRG4</accession>
    <name>A0A9P6MRG4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001091</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001243">
        <property type="protein sequence ID" value="KAG0010913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRG4"/>
    <dbReference type="OrthoDB" id="2439785at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0010913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="319" mass="34566" checksum="E9D57A8B432E945F" modified="2023-09-13" version="1">MNILLPASYGHTYFPVPVPTILALRSPLDLGSKKQSLESHKVSEILHLPLRIGEKPSNPGFASPENVSTSASETNKGSDQDSSSNTITSLPNLIDIGSDSEDSASIVNKNSRLPSALADLLEIDFTIGVENTVAKPPGVAIESTNGLWDPFLSITAVPTLPKNDDLIDLMDNQDYTHTPQNPRDLNEFFDPTSRNSGKIQSSGGVQDLLGDCNDDSIGRTRYENDGESQSYIDDDDDDDNDDDDDDDDDDDSNNGDDGSGDSDSDSYSDSDSYSDSDNEYNEGFNGLWHTIGESKILLDLATLDVIKAELDKSDLYNSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRL1</accession>
    <name>A0A9P6MRL1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_000989</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001219">
        <property type="protein sequence ID" value="KAG0011040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRL1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="153"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0011040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="282" mass="32543" checksum="4EB7657FBF3612C8" modified="2023-09-13" version="1">MVLKGSPAHLFQTCLLEGCPRLQRLYLNLDQVPRSLSISRDMTKTANSFQSSVRSLILKGWWVATETADLPLFIRAWFNNLQYLKTDVAQFSCNKSLIESLKSMRSLRKANFLRHSLSKYDAWKLGLEEVEFKCSREWDLDHRIEISIADARERRMLARKQQLAEEAERMKRARRILEFQDALDIMSEAFSILNIMNESGTHPDDGSADHDIELSNTSSNTSHCSAVDSGCKIGMESESTDEKHRRITEDEVQDEQEANEDLISIMKSVCVFKGKRYHFREN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTC4</accession>
    <name>A0A9P6MTC4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">Mediator of RNA polymerase II transcription subunit 13</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">Mediator complex subunit 13</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="primary">SSN2</name>
        <name evidence="16" type="ORF">BGZ80_000359</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 11">Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of the SRB8-11 complex, which itself associates with the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the Mediator complex subunit 13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001071">
        <property type="protein sequence ID" value="KAG0011890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009401">
        <property type="entry name" value="Med13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051139">
        <property type="entry name" value="Mediator_complx_sub13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041285">
        <property type="entry name" value="MID_MedPIWI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48249">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48249:SF3">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06333">
        <property type="entry name" value="Med13_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18296">
        <property type="entry name" value="MID_MedPIWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0010">Activator</keyword>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0678">Repressor</keyword>
    <keyword evidence="7 11" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 11" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="MID" evidence="15">
        <location>
            <begin position="1142"/>
            <end position="1318"/>
        </location>
    </feature>
    <feature type="domain" description="Mediator complex subunit Med13 C-terminal" evidence="14">
        <location>
            <begin position="1337"/>
            <end position="1533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="280"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="312"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="337"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="446"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="718"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="773"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1504"/>
            <end position="1546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1640"/>
            <end position="1683"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1761"/>
            <end position="1861"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="193"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="317"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="337"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="358"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="378"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="389"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="778"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="1504"/>
            <end position="1520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="1532"/>
            <end position="1546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="1645"/>
            <end position="1657"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="1762"/>
            <end position="1779"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="1780"/>
            <end position="1817"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="1818"/>
            <end position="1830"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="1849"/>
            <end position="1860"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU364134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF06333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF18296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0011890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1916" mass="208416" checksum="9602992F9E3FF0D4" modified="2023-09-13" version="1">MYLSSSNLVFQPTFQHHRLRTLDALDLDPRQSSEKELSVLLSPHGTRAVLKLGGTTEFTDDQTQKCLEDWANIFGTNLDIVNDMTLSLPRLVTVSIKSGVNEILLQYPTERVFVPVSCKESPSDVGQLDGMGSRNLGFIEDLGAKFAMWSWQEKTRNTIISPAVPKLVQPASEHTPILAEPRNRLKAGSSAWLQQQQQMQQQQLQQHQQQQQQQQQQEQFQQQQQDSLARRDTSDTNHIDYWSYTDPHAYLTSIVLNSCANAEPKGADSPSAIDNQVSLVVPPASSKPSKSKKTMSSKTGESVEADGWIRKKPKRNTAISPKFNNFGSMDQPDAVQSAWSTGLNSGSMQASDIESGFNNNDSSNNNQYSSSANAESSIQQEPIATDAQSSNTTTNNNSYPIDLPNDDSDMMSGLIDMNSILGLYGAGGSDDLGDWGEVTKDDFSFFDEQPRSAPPRSLPKTTAPAFDSQPIQSSIPVTSLATMTPGTSTMGSSDALMNTFSDMRSPFGKVVTTSSPMNDDSLFANMDLDLASFAQPTPPSSAVVSLTVADKLSVNPSEGSAALPSTDQLITNQVPQDIGIPTTALHGMISDKDSSHHSLQLHMATAEQSVMKRSSILVEQVHSPIQSYIPSSFAPLKIIGDYFVDDSKYQAGGRYVYKRLYKRRKSSVPSSNNIYRRESKMLPFYQPGKDQEWIMPARKEKQQRKLKSRVFTFGINWSPTKKEESTPSPRTKNDVVAFKQEEDNTSGILGKNKATISTAAWGISALSLQYGKRKNENDSSSGDSDSESTSTSSDGDSDGNDSISFNSRQPAFGKLTRGYQTGDDKDSGSSEFWSIQGINSSKFVDAILTQSTDHSVGGILLGLSPFAEAATKGLTSTTRIAEQDSGRGRIKPWTSAEAYHAEVEYDTPFMPAILSAAPPALVNESLMVQESLATEYFLDAVKTLCEQAIIGDYPFAGSNEATGTSGEITEGESFHVMLARRKTMSDFLHRGVATVPALGDESFRNMMEMKTIIFELFDRLRGNQSDNVVALPVPSDASQDMTMSMTGIHGHHHHSSQSNISPPVIMKGPLTLFQYFTLAEAQQMPSKYGKYQVKKKKPAEPALLQLQPPDIVVGHNEEWLEASPTILRFWEKLSLEPYSSKKNISYFVVFPEGADLESSVSKFWRELSVVFESSLLGKHQPGTLQDYKPGLVPIPLLDALAGESAEARQVRSYVDGCQRLGSILGGISLQRDVHIVIYMVNPFSHGAGYFDLCRCFSIMMTQFRTAAMGSLLTPLEQQRERLVLQLVPIQHVIYPSMFGGYLRFGLKDIAFTVYTKCKLFLERPTYSQNMMARINTYAPSFALAKTAPSSILFDASQKPNSLPKPPATLHVGYGLSLDGRWLICVWTDHRGEMLEHMALDLENCPSNIMMSTRTNGDLNSINNGDIDRSLMSCLQEIWTRTKVYQKRGSFSWKTVVCKLGLMSHQELQEWKRLISGAGYTAIVAVNIDSPLRLYPHGRSTDYLSSGTPGASGINTPSNLGTGQGTPLAGPSTPLSQSLGLNNINNSTPDISTAPVTPMGLGNTGNSAGLNNVGAGLGIAGTGTGGNTASQGGSGNMGGIGGLSGNEVLENGAGQVYAIILNHRIPLIVPRREAGLGRYGNAQLAHSDRQRSNLDSKSDTNMGDINMGDASPLSIPKSNHVQDQGQDVDMGYKLKLEEQGKSEETISLSSQSKSHATGESDVILPLSTGYLIQVPIQSNSVMREKHSLEALGIEVHLLHLQRTPTTTPSSASSSNPPNASGVSTGVLLSNINSSSPYQQHSTAYHLQRHSAASPSAPGQQYRSSSYSTSQYPGSPLMASPSAVLLGGGQNQTPANQQQQSNAGTTIKATVAANTTREILKQFHALSYLSLSPVQTNCLPNHLVLVERLSRVLLLVQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTV3</accession>
    <name>A0A9P6MTV3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_011445</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000920">
        <property type="protein sequence ID" value="KAG0012888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTV3"/>
    <dbReference type="OrthoDB" id="531564at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045271">
        <property type="term" value="C:respiratory chain complex I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044980">
        <property type="entry name" value="NDUFB2_plant/fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36987:SF1">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36987">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 2-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0012888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="65" mass="7160" checksum="3D22A419F940DC0D" modified="2023-09-13" version="1">MAGFHPHMPATRYSVTAKALGAAMWFWVMYKAKEEGPVVLGLRHPWDGHGHGHGHGNAHAEGEHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MU27</accession>
    <name>A0A9P6MU27_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_011473</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000926">
        <property type="protein sequence ID" value="KAG0012842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MU27"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="322"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="334"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="345"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0012842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="412" mass="45058" checksum="96AFC0CD78F4A13E" modified="2023-09-13" version="1" fragment="single">LLVIGLAPVIVFGIVHSGSSTIAIISQGSCFLLPIILVIWVRIRSGLYTRARNNFKYQSQKLLRTWTIQDAELYAVQWKLRQRPRRVAKRWLGGYRSSEQDSRTNPTNNVTQERGQPDGRNAGTGLNHVQADQTHVSRGTLSVIHSEPLSSQQSNGHSTTNLYQQESISIITEPLPVANTNQTIRFNTQLHITVTNDSIVGTDDVATEALLDDTNQTLPTTTSISASTTGENRENTTVFGYLRECFRGPSHFSRVLQERKVWLIEISIRDCQLDDYALTVPTPVYCGYRLPEYEDAVVTGSGDGSPTGTLARLGASASRLGLNRHIEEPPAYESDTDEDSDDDDNGRSGHGQDTERANVDDVVVACPLPSGSHQAPEMIMIQRSEVASAVVLSLAGQTADTSITIPTPGSSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MW49</accession>
    <name>A0A9P6MW49_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">10TM putative phosphate transporter extracellular tail domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_009512</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000578">
        <property type="protein sequence ID" value="KAG0015971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MW49"/>
    <dbReference type="OrthoDB" id="1076608at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022257">
        <property type="entry name" value="PHM7_ext"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12621">
        <property type="entry name" value="PHM7_ext"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="48"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="10TM putative phosphate transporter extracellular tail" evidence="3">
        <location>
            <begin position="248"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0015971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="318" mass="34531" checksum="8D39D1ED241480AF" modified="2023-09-13" version="1">MFLYVYRQPFDLGGLILPRIIDQMYIGLVIFELVMLGLFILQKAVGQSVVMFIFVVLSLFTIVISRNSVYKPLIKYLPVEAFEAQAVHAAASGNATGVVSASDTAPANAGTRDIARMPDLEKGNPTANFGGATERREGSTTGLEHIEPIPPNSADSTRRGATPNESRHLRDESVTRSPLPSVRIEKTGDGVPGSTKEEASKLPQHRALLSLRGSEFDYPGTGSSLQVLGANHSVLSSSDSAADRIVPENLAYFNPLLWRQVQPIWLPKDPRGFAELETVELNDAGVPCTTSDATMDMKGHISVDVSRRETAPGEEVWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MW94</accession>
    <name>A0A9P6MW94_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_009499</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000575">
        <property type="protein sequence ID" value="KAG0016010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MW94"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0016010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="60" mass="6568" checksum="53B9081D81019F67" modified="2023-09-13" version="1" fragment="single">MSGRLRDEFRMENNLDSEVSDVLKGYAPGDISNMFLTPVGLGPIMGSKSGYQRQTTTVTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWL1</accession>
    <name>A0A9P6MWL1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Leukotriene A(4) hydrolase</fullName>
            <shortName evidence="12">LTA-4 hydrolase</shortName>
            <ecNumber evidence="12">3.3.2.10</ecNumber>
            <ecNumber evidence="12">3.4.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">LTA4H</name>
        <name evidence="14" type="ORF">BGZ80_009630</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>an epoxide + H2O = an ethanediol</text>
            <dbReference type="Rhea" id="RHEA:19037"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:32955"/>
            <dbReference type="ChEBI" id="CHEBI:140594"/>
            <dbReference type="EC" id="3.3.2.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11 12">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="11 12">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the peptidase M1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.3.2.10" evidence="12"/>
    <dbReference type="EC" id="3.4.11.-" evidence="12"/>
    <dbReference type="EMBL" id="JAAAID010000594">
        <property type="protein sequence ID" value="KAG0015796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWL1"/>
    <dbReference type="OrthoDB" id="79562at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004301">
        <property type="term" value="F:epoxide hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09599">
        <property type="entry name" value="M1_LTA4H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.390.10:FF:000003">
        <property type="entry name" value="Leukotriene A(4) hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.320:FF:000001">
        <property type="entry name" value="Leukotriene A(4) hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1730:FF:000004">
        <property type="entry name" value="Leukotriene A(4) hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2010.30:FF:000001">
        <property type="entry name" value="Leukotriene A(4) hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2010.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.320">
        <property type="entry name" value="Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="entry name" value="tricorn interacting facor f3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045357">
        <property type="entry name" value="Aminopeptidase_N-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012777">
        <property type="entry name" value="LTA4H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049980">
        <property type="entry name" value="LTA4H_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038502">
        <property type="entry name" value="M1_LTA-4_hydro/amino_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034015">
        <property type="entry name" value="M1_LTA4H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001930">
        <property type="entry name" value="Peptidase_M1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015211">
        <property type="entry name" value="Peptidase_M1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02411">
        <property type="entry name" value="leuko_A4_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45726">
        <property type="entry name" value="LEUKOTRIENE A-4 HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45726:SF3">
        <property type="entry name" value="LEUKOTRIENE A-4 HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09127">
        <property type="entry name" value="Leuk-A4-hydro_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17900">
        <property type="entry name" value="Peptidase_M1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00756">
        <property type="entry name" value="ALADIPTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01263">
        <property type="entry name" value="Leuk-A4-hydro_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="Leukotriene A4 hydrolase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 12 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 11 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 12" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4 12" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11 12" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M1 leukotriene A4 hydrolase/aminopeptidase C-terminal" evidence="13">
        <location>
            <begin position="462"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="290"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="9">
        <location>
            <position position="377"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="132"/>
            <end position="134"/>
        </location>
        <ligand>
            <name>a peptide</name>
            <dbReference type="ChEBI" id="CHEBI:60466"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="260"/>
            <end position="265"/>
        </location>
        <ligand>
            <name>a peptide</name>
            <dbReference type="ChEBI" id="CHEBI:60466"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="289"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="293"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="312"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="563"/>
            <end position="565"/>
        </location>
        <ligand>
            <name>a peptide</name>
            <dbReference type="ChEBI" id="CHEBI:60466"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR612777-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR612777-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR612777-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU361141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM01263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0015796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="611" mass="68772" checksum="8B3E7389CF7E1D88" modified="2023-09-13" version="1">MPYDPNSLSNLDEVKTNHIHLDLAVDFIAKALTGSAELDIEAIADNVSKVVLDTSFIDIRSVSAGGAALKHSLEKRHEKFGSALTIELGQTLAKGGKAKIVIEYATTQECTACQWLEPSQTVGKKHPYLFTQCQAIHARSLVPCQDSPSIKLTYSASINAPLRAVMSAVPTGEEKQANGTTTYKFHQKTRMPSYLIALAVGNLEGREIGPRSTVWTEPEVIEAAAWEFVDTETFIKKGEELLTPYDWGRYDLLVLPASFPYGGMENPCLTFVTPSLLAGDRSLVDVVAHEIAHSWMGNLVTTENWEHFWLNEGFTVFVERKILGRMQGKEHSEFSAIIGHKALVESVELYGKDHPFTALRPCLRGEDPDDAFSSVPYEKGFNLLYYLEKHLGGAEVFEPYLRAHVQEFAGRSINTDDWKAFLYSFMEKNFGQEKVDLLNKVDWEAWLAGTGMPPVENKFDDTLAKACNCLCKKWNESRHENKPTGFSAKDIEEFSSNQKVVFLERVSEIEPLPHSHLDLMDELYHLTEVRNSEVKFRWQMICLKANYEKIYPEVVAFATSMGRMKFCRPLLRSLYLAKNGAELARTTFQNNRSFYHPIAATMIAKDLGLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXD5</accession>
    <name>A0A9P6MXD5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein YIP</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_009576</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Golgi apparatus membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the YIP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000587">
        <property type="protein sequence ID" value="KAG0015868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXD5"/>
    <dbReference type="OrthoDB" id="440385at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048280">
        <property type="term" value="P:vesicle fusion with Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045231">
        <property type="entry name" value="Yip1/4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006977">
        <property type="entry name" value="Yip1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21236">
        <property type="entry name" value="GOLGI MEMBRANE PROTEIN YIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21236:SF2">
        <property type="entry name" value="PROTEIN YIPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04893">
        <property type="entry name" value="Yip1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="156"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="214"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="243"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="Yip1" evidence="8">
        <location>
            <begin position="117"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="31"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="34"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0015868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="262" mass="28570" checksum="7410F92CB4A4D20E" modified="2023-09-13" version="1">MSVLFDQNNGYYDQQSSQTSDNLQFYQSQYADPSSYGSHQHQHQQRSTSFHSNTLTSTPDIGYGGYTPGIPGSQMNSQPISWLAAFSAGGLEGEPPLLEELGINFSHIKTKSFTVLNPLRPVDRNIMDDTDLAGPLLFCLAFGTFLLLSGKQHFGYVYGVAVVGCSTLYIILNLMSPQGVDIPKTASVLGYCMLPLVMLSSLSTLFVLNGGLGYILSVLAIVWCTYSSSGFFTAVLGMNDQRFLVAYPVGLFYGCFALMTVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MY97</accession>
    <name>A0A9P6MY97_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Calcineurin-like phosphoesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008540</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000466">
        <property type="protein sequence ID" value="KAG0017186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MY97"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07379">
        <property type="entry name" value="MPP_239FB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051693">
        <property type="entry name" value="UPF0046_metallophosphoest"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12905:SF0">
        <property type="entry name" value="CALCINEURIN-LIKE PHOSPHOESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12905">
        <property type="entry name" value="METALLOPHOSPHOESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="1">
        <location>
            <begin position="57"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0017186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="350" mass="39529" checksum="362CA0CEB19F0D6C" modified="2023-09-13" version="1">MFSKPRPPPQNFRVIHQPVQDDKDTNMDVDKPTTPLPPNVYMVPNVPVEKPGPNWLRMVCISDTHNTTDINNYSIPEADVLIHAGDFTKMGTTAQIDQFICWMKSLTNIPLKIIIAGNHEVTLEKEFYETNWSKFHPAKEDQDAAVNMLRTAGHGIVYLDNESCNIDGAKILYKKWRKNEKQNMKGKTLQQIHAEGAAAATASETAAVDPRQDWIEGYKVWGSPWQPEFFNWAFNEERGKLHEIWKLIPTDTDILITHGPPEGHGDIVPENNNLHAGCSELLARLKDVKPLYHIFGHIHQGYGVSQIEWPPEPTIDGHQLVSPTVCINASTCTVRYRPLNSPIVVDLPPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYE4</accession>
    <name>A0A9P6MYE4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Chaperonin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">HSP60</name>
        <name evidence="4" type="ORF">BGZ80_007031</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the chaperonin (HSP60) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000353">
        <property type="protein sequence ID" value="KAG0018557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYE4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03344">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000001">
        <property type="entry name" value="60 kDa chaperonin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00600">
        <property type="entry name" value="CH60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001844">
        <property type="entry name" value="Cpn60/GroEL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02348">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000592">
        <property type="entry name" value="PRK00013.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009487">
        <property type="entry name" value="PRK12849.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009488">
        <property type="entry name" value="PRK12850.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009489">
        <property type="entry name" value="PRK12851.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45633">
        <property type="entry name" value="60 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00298">
        <property type="entry name" value="CHAPERONIN60"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0018557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="588" mass="62028" checksum="203DCD21DF8262E5" modified="2023-09-13" version="1">MLSITRALKAKAPIARQVTSAFSIPSRLSNARLYSSHKEINFGIEGRAKLLKGVEVLAKAVAVTLGPKGRHVLISQPYGTPKITKDGVTVAKAITLEDPFENLGAKLIQDVANKTNETAGDGTTTATVLTRAIFAEGVKNVAAGCNPMDLRKGVQMAVDAIVEFLRENKREITTTQEIAQVGTISANGDKAIGNLLAQAMEKVGKEGVITVKDGKTTEDELEITEGMRFDRGYISPYFVTDTKSQKVEFEKPLILLSEKKISVLQDILPALEAAATQRRPLLIIAEDIDGEALAATILNKLRGQLQVAAVKAPGFGDNRKSILGDLATLTGGVVFSDELDVKLERLTPDLLGTIGSITITKEDTILNGTGAGSNEAIAQRCEQLRSLIADPSTSDYEREKLEERLARLSSGVAIIRVGGQSEVEVGEKKDRIVDALNATKCAVDSGVLPGGGTALLKSLKVLDTLKGDNFDQQLGINIIRSAIQVPSKTIISNAGGEGAVVIAKVVENDNFHFGYDASVGEYGDMYSRGVLDPFKVVVTGLKDAAGVASLLSTSEAMIVDAPSNDKSPMGGMGGMGGMGGMGGMGGMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZN2</accession>
    <name>A0A9P6MZN2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">[4Fe-4S] proteins maturation</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ISA2</name>
        <name evidence="7" type="ORF">BGZ80_005200</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HesB/IscA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000258">
        <property type="protein sequence ID" value="KAG0019838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZN2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120510">
        <property type="term" value="C:mitochondrial [4Fe-4S] assembly complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.300.12:FF:000006">
        <property type="entry name" value="Iron-sulfur cluster assembly 2 mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.300.12">
        <property type="entry name" value="HesB-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016092">
        <property type="entry name" value="ATAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000361">
        <property type="entry name" value="ATAP_core_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035903">
        <property type="entry name" value="HesB-like_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00049">
        <property type="entry name" value="iron-sulfur cluster assembly accessory protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43011">
        <property type="entry name" value="IRON-SULFUR CLUSTER ASSEMBLY 2 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43011:SF1">
        <property type="entry name" value="IRON-SULFUR CLUSTER ASSEMBLY 2 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01521">
        <property type="entry name" value="Fe-S_biosyn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89360">
        <property type="entry name" value="HesB-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core" evidence="6">
        <location>
            <begin position="121"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0019838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="229" mass="24909" checksum="714F6C57D617FE95" modified="2023-09-13" version="1">MASCLKNIAMLPRVFAPGTRLSKQTLTSIHTRACAANVSVLSASASQMTPAIKTCFYSSTALRSWKTLSQKSHMPLSLISRTQLRFNSNTATAVAATDNTSLTSLKVHNPQYDESGNELTVDITERAVKQLKHIAARDQNPMQALRITVDSGGCHGYQYLMDLTDTVNEDDVIFEKDGARVVIDTITLPMISGSKIDFIEELIGSAFKVLANPHAAHSCGCDTSFEIKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZX6</accession>
    <name>A0A9P6MZX6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Threonine--tRNA ligase, cytoplasmic</fullName>
            <ecNumber evidence="3">6.1.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Threonyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="primary">THS1_1</name>
        <name evidence="16" type="ORF">BGZ80_007015</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>tRNA(Thr) + L-threonine + ATP = L-threonyl-tRNA(Thr) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24624"/>
            <dbReference type="Rhea" id="RHEA-COMP:9670"/>
            <dbReference type="Rhea" id="RHEA-COMP:9704"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78534"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.3" evidence="3"/>
    <dbReference type="EMBL" id="JAAAID010000352">
        <property type="protein sequence ID" value="KAG0018571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZX6"/>
    <dbReference type="OrthoDB" id="5423599at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004829">
        <property type="term" value="F:threonine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006435">
        <property type="term" value="P:threonyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01667">
        <property type="entry name" value="TGS_ThrRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00860">
        <property type="entry name" value="ThrRS_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00771">
        <property type="entry name" value="ThrRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000009">
        <property type="entry name" value="Threonine--tRNA ligase 2, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.800:FF:000003">
        <property type="entry name" value="Threonine--tRNA ligase 2, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.30:FF:000006">
        <property type="entry name" value="Threonine--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.980.10:FF:000005">
        <property type="entry name" value="Threonyl-tRNA synthetase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="entry name" value="Anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.980.10">
        <property type="entry name" value="Threonyl-trna Synthetase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00184">
        <property type="entry name" value="Thr_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002320">
        <property type="entry name" value="Thr-tRNA-ligase_IIa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047246">
        <property type="entry name" value="ThrRS_anticodon"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033728">
        <property type="entry name" value="ThrRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00418">
        <property type="entry name" value="thrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11451:SF46">
        <property type="entry name" value="THREONINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11451">
        <property type="entry name" value="THREONINE-TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02824">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07973">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01047">
        <property type="entry name" value="TRNASYNTHTHR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="TGS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="ThrRS/AlaRS common domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TGS" evidence="15">
        <location>
            <begin position="70"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="14">
        <location>
            <begin position="342"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00073157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0018571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="721" mass="82214" checksum="00E2417D533F9011" modified="2023-09-13" version="1">MAEIENKVEDLSLNAPAQDKAQGKGKEKKPKKTVPEGAFPLEVSPAPEYIAHRIAMFDELKKKADEADAAQPRVPITITMPDGSTREGTSWETSPLDIAKQIAKSLAERVVIAKVDKVLWDLERPLVASCKLELLDFENEEGKAVFWHSSAHVLGEACEKHYGCHLCIGPPIEDGFYYEMSMTDERVVSNSDYTNLETVAKNAIKEKQQFIRLEMKKEELLEMFKHNPFKIQLIQSKIPDGTSTTVYRCGPLIDLCRGPHIPHTGRIKAFAVMKNSASYFLGDAKNASLQRIYGVSFPDTKQMTEHKKFLEEAAKRDHRKIGKEQELFFFHDLSPGSCFFLPHGARIYNALMDFIKAEYHKRGYTEVMSPNMYNVKLWHTSGHWQNYQENMFSFNVEKETFALKPMNCPGHCLMFGIRERSYRELPLRFADFGVLHRNEASGALTGLTRVRRFQQDDAHLFCRLDQLGDEMDATLDFLQHVYGIFGFEFSLALSTRPEKFLGAIADWDTAEKHLTDALNRFGRPWTINPEDGAFYGPKIDILIRDSLRRSHQCATIQLDFQLPERFGLEYRNSGGEASDFSRPLIIHRAMLGSLERMIAILTENCAGRWDFWLSPRQIQVIPVAAALIPYAEKVQKQFHDAGFYVDVDTSDSTLNKKIRNAEIAHYNFIFVVGAEEESSNSVNVRSRDDIDSKAKGQVRPLEEVLPKLKELKEKKLKGSRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZY5</accession>
    <name>A0A9P6MZY5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006903</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000344">
        <property type="protein sequence ID" value="KAG0018659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZY5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="402"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0018659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="461" mass="53524" checksum="370965B8FCD56418" modified="2023-09-13" version="1">MYYNNNLGGLKYNLRTLVYDKPWIECLTRLRIMSWTPFERQVLSVIYRNGQTLRELRYEYLEQDWLRGQDLPEMPRLQTLELGNFKLTKDRLRKFILAKCPKLETLGLVCVKVFPKDTVVPPRGRPDLDQFVRAQSHNIVRDGEGRPRTGDVRLISSGAKQQQCQQRQKTNSGKSNVTSHSTPRTSKDDQYVRGVKRYLVYDKVYAVLDLFPDLESIVFRPEKPFHTVWDWPPTSEYEGMIKSTCHNLHSLTVETFPPHQETWGRLIRSISQLTHLSLEGIAEYDRMIVGEAIQYHFPMVESVHVGTSMTNPAIVLQFLEKCPRLQRWSCSENVAISATSLKMSLLRVDRKTRWVCEEMREMIWPKNVAGFGPQEIDRLVASLQNKSSTLRIESPLELPAIETPGGLRDQEEKNKGVNVSRMQKDSETESRERIFKLLLSALESMKYLKCISFGSQMHRIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0C0</accession>
    <name>A0A9P6N0C0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">chitin synthase</fullName>
            <ecNumber evidence="2">2.4.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">CHS3_1</name>
        <name evidence="13" type="ORF">BGZ80_005720</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.16" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010000281">
        <property type="protein sequence ID" value="KAG0019512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030428">
        <property type="term" value="C:cell septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004100">
        <property type="term" value="F:chitin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006031">
        <property type="term" value="P:chitin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04190">
        <property type="entry name" value="Chitin_synth_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004835">
        <property type="entry name" value="Chitin_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054295">
        <property type="entry name" value="CHS4-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914:SF16">
        <property type="entry name" value="CHITIN SYNTHASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03142">
        <property type="entry name" value="Chitin_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22997">
        <property type="entry name" value="CHS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="439"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1037"/>
            <end position="1059"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1071"/>
            <end position="1091"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1098"/>
            <end position="1122"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin synthase 4-like" evidence="12">
        <location>
            <begin position="349"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="511"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1183"/>
            <end position="1230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1257"/>
            <end position="1339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="511"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1219"/>
            <end position="1230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1258"/>
            <end position="1272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="1293"/>
            <end position="1302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1303"/>
            <end position="1333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF22997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0019512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1339" mass="148632" checksum="A1557515FBCA818D" modified="2023-09-13" version="1">MDSSYHDLENPSVTIAEPQNRRQSQGGLIVDTTKRNTNFRRQKSLVRPERERVDRNHPQYFYRNVTQNLDSSHIMIQASTTGTDPTGVPPNRTTGGGVRRGKSVLGREIEKPGHVRVKPTSKRKKFVEIKDPLKKEKWEWPSKWIMYYSAVTCCFPAAVLSKCGGMRTPEIQRAWREKIALVSLIIMMVFAVAFLTFALQKALCQDEESGKFVAGSRPEDVIVDGMGYYFNAEDSGNGETVWMHPSLNKDISSEPVDIMNAPGNSAKGMDASFLFQDVAGGACDGLITRTTAASPSDTQANYYFPCIMRSIDGTTAPNTTEGTAAACHIPTADRVFWNSLKSQFNAPTYYTWDNITDPNRNLFAYDGDVIDADILKFIKTDFTLDDSLLALRNGSIRLQRDLSFLFVQRKMTNVGACLKQIARVGAMDSKTIGCVTSDVITYVSLVIILAVVFIKFFLAVFFGWFLSHKLGGFENETYEDRMKRSEQIEAWSSDIHRPAFANAKRSTFFPTSSRFTPTTNNPGSSTSLGSPALGAPNARPVSSFIRPTSTFVRQTPPGSPAINPAFLSASSASNTSLHRASYLNQSFGPNGTPPPSPPPVPHPMRPVSAMNLSGVRNISRRSSMSSSTAIQQSNCPMPVSPHVIPQPPASFQPFNFPLIHTMALVTCYSEGVDGLRTTLDSIATTDYPNSHKLIVIICDGMIIGAGNNMSTPDICLSMMQDDLIPRDEVVAHSYVAIADGTKRHNMAKVYAGFYKYDDETVPDKKLQKRVPICLIVKVGGPTEQNMPKPGNRGKRDSQIILMSFLQHVMFDERMTSLEYEFFNSIWRLTGVSADRYEIVLMVDADTKVYPDSLSRMIAAMAHDHEIMGLCGETKIANKTDSWVSMIQVFEYYISHHQSKAFESMFGGVTCLPGCFCMYRIKAPKGGNGYWVPILANPDIVEHYSENVVDTLHKKNLLLLGEDRYLSTLMLRTFPKRKMMFVPQAICKTVVPDTFKVLLSQRRRWINSTIHNLMELVLVRDLCGTFCFSMQFVIFMELVGTVVLPAAISFTFYLVGISIYRAISHNDSIPDTTVPLLLLAAVLGLPAVLIVMTSRKMVYVAWMLVYLCSIFVWNFVLPAYAYWHFDDFSWGQTRMVAGEVAGEDHGGKEGQFDSSHIIMKRWGEWEKERRQKAAILAGLPTPQFMVSDSEDWPREEELSDESSSSRRTGDSSQPFARQMTTGSGSTGYTLSDNPVYTGPVMDSIPLLNMHVPAPGGTIGRQSFITPDRMSTLTPPVMGPNRQFTPSPKLGPTSYAPPPLPPSGPRLASVDTRAASPTPLLNSNNNSTPSRPASPMQRQDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0G5</accession>
    <name>A0A9P6N0G5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PROP1-like PPR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_006269</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000309">
        <property type="protein sequence ID" value="KAG0019124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0G5"/>
    <dbReference type="OrthoDB" id="411857at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033443">
        <property type="entry name" value="PROP1-like_PPR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47932">
        <property type="entry name" value="ATPASE EXPRESSION PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47932:SF44">
        <property type="entry name" value="MIOREX COMPLEX COMPONENT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01535">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17177">
        <property type="entry name" value="PPR_long"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PROP1-like PPR" evidence="4">
        <location>
            <begin position="533"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="552"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="587"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="696"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="809"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="36"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="104"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="342"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="36"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="111"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="362"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0019124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="879" mass="99091" checksum="F237BEB78A395284" modified="2023-09-13" version="1">MMNLKTTALLGNLTRQNVSRQLLPLSNSKNQVITLSQRTAQPTSANTPSNPVRSFSSSQANRENNNNANATVHHTQQHFYTSHHLTPNHRLQSPIATNLAFHNQQSRHNHQSNGRGPEDASTTKPKPKHSELCKNVLEAINGQDARAVFPFLQEMRHQGFYADSALSSRIVTHFLNMDCPQDAEKALAMLCDCFFNYNHGRGMPPLQKQTYTSLAKDIANYSSDFSQTLSLARLMDRHDLLASSGLSDGTLKTYRHIKSTLGLEHMKGMLSNLDVETLLAMQASLTKSIARYRQLIEILLDAKDMHLVPSREICSRISLSFVELNDYSGQLAWDTAVQEIHPGFKPSAPQDMQAEPQRRQYKNQNQKQHHQSQQNRSSNVNRRDNSRANPDPRAQIALRSGDPSEAIIRACRFGYAAVALDEISKMLNKNLLPSPQAIADTIQVCAKREKERTTNYQDLYDLAMRSLDAIQDKTHRRAAEYEVYNAMLVANATLGDMNSAKKNYDDIVNLGQFPDATGYATLLIATTTGAVDEAHDALRILEEVKRHNIKPNIFFYNVVIGKLSRGRKIERVLEVYEDMMMNNIRPNAITYGSLISACTRVGSEDMARNLFREMTSSPNYHPRQGPHNAMIQFYVRQKKDRDAALEYYNDMLQRKLPPTEHTYTLLIEAFACIAPFDMTEANRLVQSLKHGPVRASEAHYGALIHAYGVEHRDPSTAEVVFNNMLEAGITPKGPAYQSLIESYITNGNVRRAVKLRDELLASGHASSAYIENSLIRGYGQERKVAAAEKVFNKMTDPHEPKLPGAIVKEPSTYQSMVSVYLENKKLDKAYATLEMMRDQRYPELVIKPVEEAIQAAAMGMTFNMTYYMDKNDTLQFTNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0U4</accession>
    <name>A0A9P6N0U4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phosphatidylglycerol/phosphatidylinositol transfer protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_003636</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000198">
        <property type="protein sequence ID" value="KAG0020754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0U4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003172">
        <property type="entry name" value="ML_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010308">
        <property type="entry name" value="TRP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040241">
        <property type="entry name" value="TRP_Flc/Pkd2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31145">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_7G01610)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31145:SF6">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_7G01610)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02221">
        <property type="entry name" value="E1_DerP2_DerF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06011">
        <property type="entry name" value="TRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040486438" description="Phosphatidylglycerol/phosphatidylinositol transfer protein" evidence="4">
        <location>
            <begin position="16"/>
            <end position="1196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="453"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="domain" description="MD-2-related lipid-recognition" evidence="5">
        <location>
            <begin position="16"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="TRP C-terminal" evidence="6">
        <location>
            <begin position="164"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="317"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="551"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="697"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="944"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1042"/>
            <end position="1121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1139"/>
            <end position="1196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="329"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="944"/>
            <end position="958"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1051"/>
            <end position="1069"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1085"/>
            <end position="1106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1139"/>
            <end position="1148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1168"/>
            <end position="1182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1187"/>
            <end position="1196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00016056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF06011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0020754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1196" mass="128491" checksum="9709ABEFCB7E2375" modified="2023-09-13" version="1">MVVLACTLFPAATTAWPYADCSGSGDYPVYNLDAVTAHFDPTNKIVELTIQGNFSNVYQYPAAETSQWRARVTADILNTQLHASEGPACSIITGGCPATSGPATISTNFTIDQAAPFAELMIFLQIQSANNQMIVCIGVLLEQSKDNINTIVSYLPLAVALYSGAVSLASIILRATTGNGFMGALATYGLPSTSDVINVHTPGLFDVIFYTQFMVMTGQLSINYPSFYVTFTSLFHWSFLEFRKSFAGDGPANSTSVLPYGGAGSVNQINGPRNGFSSSLRKRFLPEPWNVETSPFLTVPTEPGFLIDGFPSTTPSAYSSSRLLKRQNPKTTSPATHTTIPSSPSPSSSDNVSTDTSSPSPTTTADSTSSTSSTKTKSKTTTSALSSSSSSSAPSPTSTTSPPPVVPNVTDPFSNKNLTFVKYNVSKYGVEAYAAAFGANPSSLFLCTLINTIMAGGASLFISAFLLVVAWLIAKESHQKGKTLEHAFNFVADHSETGGDWTLTNRPPSQMPESSQVMPIKSRQYTVQPYSSIGDINALSEDNLIGRHSLYQQPHQSPGYRRSAFPSNGVPHAASDLRSEAVVPLSISAGPISAQSSTSLPRSPSIDSVDGPAIPLQPTQLSSIRFQTPRESYAKTQRMTHQQAVPDLRNRRMSEIFRDGGYLYEPTINSTSTKAPEEKRSMIKSIKESLGGLFSFSRRTKNNPVKDGSKPKAFEVIRPPRPSTVMEITDDISQAGDDNLRELNSLGISRFFEESGLNNKRDRSLFIANPETMISRTGSVRSSASEVPRASPELIRQTSIATSIHTVSRQIPKPALNTGADMNSIYSGVGSLASEPANTENKRVSATSAQYTYSQTSAESSIADVLRSETPFKLHSGETIKVSKGPEKAVQYWSKISGQYVESTSDPLSERKQTTVLPHVSPPLLLLPTARGYFDTIHVDSSKAAATTQLTRSRTGSRPESPAESHHSSNVAASAGKMHEILDRMFSDEDDDDSETISDGEETCSTFSGRVSATIMALQKREQEECFADAQSLYRSETLEPVQEHFNSETGISSRAGGSGDGSDSVSGAMKLPYKPTRTASGTILRTYSGTSASSSSALQPRPSKSGASSRPLAQTPLYPPSMLSFTGSATSLLLPRTLSRQSSRTSLGEGFVMTKQEHDVNATQPVETRDTKVLDPLHEEPVATSKIHTNNETPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1W8</accession>
    <name>A0A9P6N1W8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_002247</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000155">
        <property type="protein sequence ID" value="KAG0021508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1W8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0021508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="232" mass="25888" checksum="B0898516D227C9E1" modified="2023-09-13" version="1">MLHDHHHDSPMQDHHHDSPMQQHRHDSPIQQHPQQQQQDTARVTAIDFLDPQPGRSARHRTINAESGRSSVGMLPPPSFAESELLTIQRRRINPRFLEVNEDGRMIKWVEPKSAGPKDDEWEFAGWGSTYFLDVTRADADRGSQRKGRTLVGVLQGIGIAGNDVVGSVFYAVGPVTVAARQYAPISMLLVSILLRPMKAIMNELAASLPFNGGLFSFWFSGSDINMNNNVGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N204</accession>
    <name>A0A9P6N204_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_003377</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000189">
        <property type="protein sequence ID" value="KAG0020906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N204"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0020906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="179" mass="19641" checksum="0AA1B515D469E539" modified="2023-09-13" version="1">MLHNNVTLKKFDNLCVDFEDIYPSELEGSISRLLGSQYLQQVSDSGTRKLARGGVLGVNFRPIISLHVQISDAITTMSGTPLPVNVHFLFLAASPQTYMSGEALRAIGVEDMVVVGEPMDDPESIRLPLLINGFKVFVQRSPSKSHFAHLNILGEDFIHASGAHVFFGGETPLFEIVFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N212</accession>
    <name>A0A9P6N212_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Pre-mRNA-splicing factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">CWC2</name>
        <name evidence="17" type="ORF">BGZ80_003344</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RRM CWC2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000188">
        <property type="protein sequence ID" value="KAG0020928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N212"/>
    <dbReference type="OrthoDB" id="10251848at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071006">
        <property type="term" value="C:U2-type catalytic step 1 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071007">
        <property type="term" value="C:U2-type catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036002">
        <property type="term" value="F:pre-mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017070">
        <property type="term" value="F:U6 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12360">
        <property type="entry name" value="RRM_cwf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000502">
        <property type="entry name" value="Pre-mRNA-splicing factor cwc2, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039171">
        <property type="entry name" value="Cwc2/Slt11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034181">
        <property type="entry name" value="Cwc2_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032297">
        <property type="entry name" value="Torus"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14089:SF2">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR CWC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14089">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR RBM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16131">
        <property type="entry name" value="Torus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="9" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="7 13" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 13" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="16">
        <location>
            <begin position="71"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="15">
        <location>
            <begin position="134"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="13">
        <location>
            <begin position="71"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="240"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="343"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="346"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0020928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="399" mass="43889" checksum="0D5DE3FDAED5C31E" modified="2023-09-13" version="1">MSRPARRQIAKEKVLGPQASGPNKGGKPGQTYNIYYGNWSGGGNRSENSHEKAQYRCDPARDSGTTKGTYNPNAYFCAFFAKGCCPNGEDCSWLHRIPTRQDQVDAGLDVFGRERFDEHKDDRGGVGSIRSDSKTLYVGQIRPTPDIQTIVEKHFKLWGEIERIKVLKDKGVAFVTYQSRLNAEFAKVAMMNQALDHDETLNIRWATDDPNPGVQAMNKRKAVEMTRQAIESKLSEDYKRVEHLPGSEEAGDLESGKRFKQPTVVDAKDTSNETQEPVPTLYVGVDGQYYYDYGSYGYNYETQQYDPARLSNYSGYTNSGNTNQASAATVPSLQDRVKASLLPSAPSKTPLASQSISKPVTPSLSSAATLGTKESEVKPVVSALGALAAYESDSESDAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2C3</accession>
    <name>A0A9P6N2C3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001281</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000129">
        <property type="protein sequence ID" value="KAG0021987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N2C3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="198"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="358"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="778"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="847"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="968"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1018"/>
            <end position="1043"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1083"/>
            <end position="1232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="780"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="868"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="884"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="912"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1020"/>
            <end position="1043"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1085"/>
            <end position="1110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1111"/>
            <end position="1125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1151"/>
            <end position="1161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1166"/>
            <end position="1183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1184"/>
            <end position="1204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0021987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1232" mass="130284" checksum="66BD77103E0B4096" modified="2023-09-13" version="1">MQCDEGTLEMPGSFKPARDHNTFENDENEIHNGNSSIAYHTPPATVMRASSVANPHESDFDISNSPTSGSPDSYDIMRYGASNSLHSQEAKRGHSPQLSLVDTVKAGATSTANSAAAAGASVIDAAKKFMNLKDDDEENEFDPYDGNEGVLPTTNYSAGPTRKNDNSHGLEFSHRSMANQSFALPVLQSTSTEPTIAASIPEVKRIPIDQPSPEPLSPHYTHTNNNNDIYASAAAGTAAVAGGLGVASIHHGHQSHVGLDNHSESVMNRARDTSNTLSIPKDNTFLVALTQAKVLLAQQEFLKRHHSLTPSMESTSASYNAPKENIHNRDHNHPEAAVVAAPVAVTTAAGVANNLRSWKESPTEDELAPVPAPAPVPSMDRVAHDTKTLHFTDPSTLRPLTEIRTFPTVEETHKPTLVDRVKDAIHRSSEYGPADPNDLTFTDPKTIGLLDRELSVPAAVGTTAGVVGAGEAIKAHSTATRGPVSDNSLASEASHDAFPADPVAAISDNKTLVFSDPKALRPVAEIRAFPVAEDTYTLTDKVKDIVHRSSEYGPADSGELQLTDPRTLGRLGEKAVVHDSGKSASRDVKPAAIATAAAGTAVATGVGVATMTHPKVETAAMSTPVLDSKTLNFTDPTTLRPLTEVRTVPPVEEPQRRSLMDKARDVTHSSFEYGPADPSHLQLTDPRSLGRMGTAAGAPVFVVPPPQPPADMKTLEFTDPKTLRPLTELRILTVVEETHKSSLVDKVRDALRRSSEYGLADPMDLQLTDPRTLRPLGEKAAAPVAAPEAVPISTATRQADTAASSHMTDHHDHSSAKPSIAAASAGAAVAVGTAGTAAMATPKHVVSPVQATTQTPMRTEISAPPRPATTTTSATTSAPDADNVNLSDIKSIQPSTDSRTIPPRPSEYGSADPRDEGLADTRPLHPMRKKVDVPAKEDLVGSQSTRSDIPTLAPLPAVAPLDIPLAHGDKTEDSMARRPLSADAAKPAPVPAPRPRRSTNAFANPITTGGAAAVVDSTAPDATSTMPTVANRSTNPFAATADTDNVDMNTNIMDPDASVAPPKMSHPEIHNTNMDISAAGVAPTMPQSRTQADNAGTYPTHQNHYTLTDNSIAAESPSSSASVPANTLATVPENHDGPIPKVQPGEENAWMKTTSTPTYPQDQDGAAPATTTSATSSTDLSPAQTQKLQQQQEGSDSSPIQSSSTKKKRRFSGFFSRLFHRHKTTDKGKQRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2L3</accession>
    <name>A0A9P6N2L3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_010779</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000079">
        <property type="protein sequence ID" value="KAG0022942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N2L3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0022942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="488" mass="56027" checksum="26E5AA2E2E70394E" modified="2023-09-13" version="1">MLCQPDSSLKITQLTVEGNLPVTKTVEQLLQDVPILATTLTTIRIEKCHIESFVYIDNILSTCVNLIDLHLEAPQPERDNPVRLELRECSDFCKDRMETPLKLQRLTIKLFWISNRVKEIVLPRCPFVKSLEIVGAYCDCGPPFCRLHAIISRCMPSLEHIHVSSGTYHAAGDKLWVSRQAYNSAKSWSFDSRQINLKTFDRLEIPPNPIPGYFLLEIESPILTSLEINIGFNGWSNADVKSALHNYLVSPAAVSLVHLRGDGATYHYARLDLGKDQNQKLWTCRLLETLHLDIRDLDILKDRDNEKSASVTRSIFGYLTQLLPRIRELRLKFNQFDFDLEGGLCLLKRLRYLESARFVFFKHGQLRERDLYWLDKYPTSPQDILRQNWIAELQDQLNLDQEALDENDPQGSSNTLKDVIECLKDDGGSSVGHHSENQGALVCLPYLESFVLEDRRKGSKLEFKDPDNSIIQLMKSIRPGCEFRITRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2Q1</accession>
    <name>A0A9P6N2Q1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_010627</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000076">
        <property type="protein sequence ID" value="KAG0023007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N2Q1"/>
    <dbReference type="OrthoDB" id="2449527at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35711:SF1">
        <property type="entry name" value="ECTODERMAL, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35711">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="383"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="439"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="493"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="383"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="408"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="441"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="495"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="513"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="540"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="562"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="592"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="667"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="721"/>
            <end position="738"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0023007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="785" mass="85949" checksum="EB79BEB25C3B2487" modified="2023-09-13" version="1">MTVTRSRRLASSTVSTSRPTPRQSGSTQRAAARGTDSITDVKINNNNNGSSNDGDDDEEKEEEDDNNIHGKRNLGTSSRIPEQADNLVLKSHPPSESKKITSLTARGTRGTRRRINKRGLAPRGKANTKPGFFSDGDDDDDVEEPRLHYLESVVVPDYHRTTKGIDIFKEVAGRARKAQKDYKAIFSVNEETPSSTTKTIEPDTALLGDSSIQLPESQQTEQIEHDDNDDPNSLLFSRLSLTPPPMMFELEEGFESMETPWQMVFDSAQSSSSLDPQPRIKIAELTLADLGNPQEDGRLDDIIDDFEEHDDDPFGFTKVERQLEKTKKLRPKLLAINEVNNRAFVTAAAGTTIDTKGSTSGNRRDSNLGNRLDRIVLERSAARKRGDVKNKGKAVDRGVPTSSDINNASGAGSDDAGGVADLDLQKAIQLSRGLDIASGEGCSSTAIPASSSGTAGNEAQSTVLTEQPSITQNDVATPSIAAIRSSRRISRMYGKSTSVHDSQDTQIASKDPSFSTENNSTTSDNNNDLSDFAFTFTNLPSTPQKPSSNNNNKNTSRTSQQDFRLSISSDDLSPIVIETTPPKKPEAGMPSSLESPSTSKTNRNARPKKYMLTEQLEALLPRRRRPKERLGLTRKGASSARLVLSSGADIESENDSDDASASSELSSSEEEDDDKEEEEAQHRGRVRKRPAKSTTSNQISSKKRRTPAESKIPQAKHTLPSSKSNVSTAATTNSSSLKSKGKEREKEKEEDEDKSGWTAAQLEAHRERIKYFQQVDDFELEVETL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N338</accession>
    <name>A0A9P6N338_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_009337</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000055">
        <property type="protein sequence ID" value="KAG0023470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N338"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052207">
        <property type="entry name" value="Max-like/E-box_TFs"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15741">
        <property type="entry name" value="BASIC HELIX-LOOP-HELIX ZIP TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15741:SF27">
        <property type="entry name" value="TRANSCRIPTION FACTOR AP-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BHLH" evidence="8">
        <location>
            <begin position="47"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="131"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="91"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="135"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="147"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0023470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="177" mass="20502" checksum="83B620C0D46062F8" modified="2023-09-13" version="1">MTFELDDVLRKYSPEQFKTCEAYDVGGVNILNKKPVDSKTALDKIKRRRETHNRVERRRRDCINQLIEELTSLLPRDDDDSQSKCHRVNVLRTAVAHIQKLTQQNEDLNRQLAVLQSDQSMSPPSIVTTPAPVMNHDHENKDDLHSQRTYNSETSQPHRINSPIFTNNQQLTCKAIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N340</accession>
    <name>A0A9P6N340_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="2 6">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">FKBP1</name>
        <name evidence="8" type="ORF">BGZ80_001567</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the FKBP-type PPIase family. FKBP1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2 6"/>
    <dbReference type="EMBL" id="JAAAID010000136">
        <property type="protein sequence ID" value="KAG0021859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N340"/>
    <dbReference type="OrthoDB" id="1902587at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.50.40:FF:000025">
        <property type="entry name" value="Peptidylprolyl isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050689">
        <property type="entry name" value="FKBP-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10516:SF443">
        <property type="entry name" value="FK506-BINDING PROTEIN 59-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10516">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="7">
        <location>
            <begin position="20"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0021859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="108" mass="11732" checksum="48C7F82792F21279" modified="2023-09-13" version="1">MGVTVTTITPGDGINFPKPGDVVTMHYVGTLENGSKFDSSRDRNKPFETQIGVGRVIKGWDEGVPKLSLGEKAVLSITSDYGYGDRGYPPVIPPKAHLNFEVELLKIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3E6</accession>
    <name>A0A9P6N3E6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NAD-dependent epimerase/dehydratase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001115</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000125">
        <property type="protein sequence ID" value="KAG0022075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3E6"/>
    <dbReference type="OrthoDB" id="2735536at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051783">
        <property type="entry name" value="NAD(P)-dependent_oxidoreduct"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48079:SF3">
        <property type="entry name" value="NAD-DEPENDENT EPIMERASE_DEHYDRATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48079">
        <property type="entry name" value="PROTEIN YEEZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0022075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="330" mass="36056" checksum="64B7493E719E8A24" modified="2023-09-13" version="1">MVKVLVIGAAGYIGLRVVQQLRRANHIVYGTTRTSSKENTLLVNEVIPIVGPLESEHQQTPPWIDAVRDENIEVVVDLSGTQDGAKVILEPLIHLSKERQSARLPKIGFIYCSGIWVHGSDVSPTSDLTGVGIETSARKTPPLVAWRPEHERQVLASYEHLNAAVIRPSLVYGGSGDIWDLYFAQIYHDIKNKASTISLKADPNAAISLVHVDDAASAFVAVVEKLELVAGQKDQYPVFDVASSHESLAFVLRRFAEELGHQGKVEFTGVPEGSSFPELFIQAFNTNINSGSTRAKTLLGWSPTKTGFAAGISIYAKAWEGSFLERNKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3I6</accession>
    <name>A0A9P6N3I6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_000734</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000116">
        <property type="protein sequence ID" value="KAG0022221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3I6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050562">
        <property type="entry name" value="FAD_mOase_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356:SF2">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356">
        <property type="entry name" value="FAD-DEPENDENT MONOOXYGENASE ASQG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="3"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="253"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0022221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="390" mass="43289" checksum="8BC2748F5953ECFD" modified="2023-09-13" version="1">MSINPTVMAAFEQLGLYEDFLKVSNPISNSHIRNADAKIESSFNISDSKELVGYEYLVVGRSKLYELLLSRVPLEKIKPGKRVISFVQNKEGVMARFQDGTTTHGDILVGADGAYSAVRQHLFKELSKIGKLPKSDSKPLSKGFICMVGHTNPLDPEVYPIFKWNRGVCDTMISNNSPWSWLTLNLPGNVMAWSATKQLDSETFADMNLRNSEWGSEANEALIKEVSDFKTPYGTLGSLIDATPRSSIAVVFLEDKFFETWTHSRTVLIGDACHKQLPSAGLGSANAMQDAIVLANCIYEMKANSYDEVVAALNGYRDQQYDRTKKQCDTMNCLSPSARAQGIAKTMMYRPQIAFLPLIPNRGTADVKPQKPSAKYLEEQANVSDYEVAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3I8</accession>
    <name>A0A9P6N3I8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Bud site selection protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">BUD6_2</name>
        <name evidence="5" type="ORF">BGZ80_009275</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000054">
        <property type="protein sequence ID" value="KAG0023500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3I8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051286">
        <property type="term" value="C:cell tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005519">
        <property type="term" value="F:cytoskeletal regulatory protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030010">
        <property type="term" value="P:establishment of cell polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1540">
        <property type="entry name" value="Actin interacting protein 3, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022782">
        <property type="entry name" value="AIP3-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005613">
        <property type="entry name" value="AIP3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056279">
        <property type="entry name" value="Aip3p_Bud6_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051825">
        <property type="entry name" value="SRCIN1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22741:SF10">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN CG32809"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22741">
        <property type="entry name" value="P140CAP/SNIP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03915">
        <property type="entry name" value="AIP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23153">
        <property type="entry name" value="Aip3p_Bud6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00806">
        <property type="entry name" value="AIP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Actin interacting protein 3 C-terminal" evidence="4">
        <location>
            <begin position="396"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="142"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="182"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="208"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="623"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="709"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="154"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="226"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="253"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0023500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="849" mass="93862" checksum="67BF0AB056712368" modified="2023-09-13" version="1">MDTATESSPTGAPVRRRKADHGPINPIETTVTKLLVATKQLLEGLTLWSTRKMTEEQVSDIFVQLATQFNLASQAFHDVNIDTSELAHIPDDLRNCLETALGEEPSPSSLDQYLPRIKEVIINLLQGLRLKQNLYREQYEAKAARSQPAAGSARSKSSGNNYRQPGSVKSPEQEGVARNQSLNTGATPAFPISTPSDEQGHAETLASLRKSDAITRRASSRRHSQRFSTVIEQNTPPVPRRNFMNDPVMLSSYPGNISSQGSTPGASPNIPLSYSQFPPMPTYDLPTSPPLSSPGVNRPLDAMSQPPTIPVPLPPSALPPIPPSTTSPLLGSSSMIHNAHNMEAAQHASLMTNGSSETIQGLNTVINSGVVDGSSALSLPLTDVPAESLDQNLTLFLQVGKSVKKTKFEGELTHSGLRMLFMEKFQYNPGQEDFPTIYVKDPNTNIHYELESMADVKQNAFLSLNVDDLENIQRKMDQGFAAISKELYEIKKVQEASEAARHKAAAAASAMANSIPERSTPTNPESSQMLRSVVQKVLTKNKTASASTSPTPSQTKISAAELKSQYDEVQTLRRDLGVVRQLYTELQSETKAILGNLAGYTTQIRKQALEQPVSSRLLIESGKVKLDKKSEDLTNKIEELQDVVEDMKINVTQRRGRPSDSSIAFADKQCNGIGQEIEELSNFIQALRPSWKKTWEVELQTIVKEQMFLKEQEALLEDLKEDRNSLLQTLVNLKKVLELQLKSGGPSREFVFQPAVDESFEGLKTVMEEVKLIEPDSDRRLKAMAQMEKLRHIELSNRIDEFEEELTTFVGASKLRKTGGALEVERQRQQRDLENLKAMFAKKDEGLPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3N7</accession>
    <name>A0A9P6N3N7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Histone acetyltransferase type B subunit 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">HAT2</name>
        <name evidence="4" type="ORF">BGZ80_000221</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000104">
        <property type="protein sequence ID" value="KAG0022449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3N7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050459">
        <property type="entry name" value="WD_repeat_RBAP46/RBAP48/MSI1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22850">
        <property type="entry name" value="WD40 REPEAT FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="30"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="32"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="49"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0022449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="432" mass="48034" checksum="E55018EC488784C2" modified="2023-09-13" version="1">MKCLFGLNPDFWVPSKAPEKTEKARGNLIDVPTNNTRTTSGTHVIPGQQAPNKPKNQSGAAKSNPYTISSKYKRDIGSAEEQRAFKTLSPISVEELSFQPGEIKGASCNPHLFETKCTMYDSSMIRSVAYTRLGSSFTPSGSERQYPVLSSLTVEMRQYGDKDSAAGVLAIRNNGQLPDSCDSSLTEGINVTTRAPILSMKCLESGHLVASSGSRNTDYTLQVWDMRDQREKAEVPVAIYDSTVLVGSGEHAQIARWDPRSPKDAFTSLACRRTEASSYHRRQFDPIYDISWNPSNSNEFITVHANAIRVWDARKMDHDGCSTLHIFEGRRLRRARWSPHHSDCIASLSLDGQVKIWKINKFDNQTDIITGAQTPELLFVHQAHELIVSDFSWCPYDEDVIATVSPGIANTAGNIQVWRPRNLHDSDANGEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4P8</accession>
    <name>A0A9P6N4P8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">cystathionine gamma-lyase</fullName>
            <ecNumber evidence="4">4.4.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Gamma-cystathionase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_009344</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-cysteine biosynthesis; L-cysteine from L-homocysteine and L-serine: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.4.1.1" evidence="4"/>
    <dbReference type="EMBL" id="JAAAID010000055">
        <property type="protein sequence ID" value="KAG0023477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N4P8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004123">
        <property type="term" value="F:cystathionine gamma-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019343">
        <property type="term" value="P:cysteine biosynthetic process via cystathionine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00614">
        <property type="entry name" value="CGS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000008">
        <property type="entry name" value="Cystathionine gamma-synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000009">
        <property type="entry name" value="Cystathionine gamma-synthase homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808:SF15">
        <property type="entry name" value="CYSTATHIONINE GAMMA-LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808">
        <property type="entry name" value="TRANS-SULFURATION ENZYME FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0198">Cysteine biosynthesis</keyword>
    <keyword evidence="5 8 9" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="8">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001434-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0023477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="343" mass="36790" checksum="4EC7F7F2ED383AFD" modified="2023-09-13" version="1" fragment="single">GFDYSRSGNPSRRAFETAVASLEGAKYGLAFSSGSATTATIVSSLPAGSHIVSVNDVYGGTYRYFTKVASAFNIEVTFVDLKDAANVASVIRPNTKLIWIETPTNPTLRLVDIKAVAEIAHKHNAKLVVDNTFMSPFFQNPLQLGADIVVHSVTKYINGHSDVVMGVAVTSNEEIYTKLSFLQNSIGAVPSAFDCFLANRGLKTLHLRMRQHAASAQAIAEALEASPRAENVIYPGLPSHPQHELAKRQQKGFGGMISFRIKGDLATANAFLRHVKFFTLAESLGGVESLCELPATMTHGSVSAEDRATLGITENLIRLSVGIEDTEDLVADVLAALEAAVKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N546</accession>
    <name>A0A9P6N546_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SWIRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_000022</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000001">
        <property type="protein sequence ID" value="KAG0024894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N546"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070210">
        <property type="term" value="C:Rpd3L-Expanded complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000087">
        <property type="entry name" value="Transcriptional adapter 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007526">
        <property type="entry name" value="SWIRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12374:SF21">
        <property type="entry name" value="SWIRM DOMAIN-CONTAINING PROTEIN FUN19-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12374">
        <property type="entry name" value="TRANSCRIPTIONAL ADAPTOR 2 ADA2 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04433">
        <property type="entry name" value="SWIRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50934">
        <property type="entry name" value="SWIRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SWIRM" evidence="2">
        <location>
            <begin position="608"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="383"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="449"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="118"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="269"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="286"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="500"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0024894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="706" mass="77951" checksum="6F7CC76085BDF2BB" modified="2023-09-13" version="1">MIMDHSIMTDHAQQLQLPSLAAMYSKDHHTHKYHAVQSREPSSFSLPKPQPGRLPVRLGLSDPRVHIYLNPPKPMSAPSHDRSQDSTLLRQGHVTLPQSRSTHSAAPTSRYPPMNFVSSSRLAPSRSSIDIAQPIRRDFELYGSTATSPRKLSHGHYAHGSTSGNGNVLESGPGAYSRSSTVPSTSPSPLPSPAPSATLSPDWHLTCNRQHHSHAQQQESQLDLLSPSSSEADLGSDTRTMPPLFSSSPPPLFPSELHASRLSPQPMVNSLSRSSNISSGSSNPSLENQAALTLPNNQSHHKLPPIRAPERAGQEVIKTSSLDTTSSEYLNMDYYSIYRQNPRLLRPEGGRFDERRHHTHAHSHSEDVTASITGDQMHHISHLASKTKPKPRMTADSTGLSRRQSMPLISTGTSRILRHEDAKMETLNKPSYNSSQDLVRSLGIHSAVSRSRPSKYHPETHSAAASSTRPVAMSIHHLLSDDSSVDMPQSDRRFYYPDNSSVSIGSESGSDSGIKRKKAHENIDDEKDGEPKKRRRMSKKRAAELGLLDEDGNFIKKRKRTKKIQDPDHVSASGFRHGGERTVQEPEEVVTLGPDVGPISLLDVKQPPMVVWKGQPLSVAGKPGYELLHPHEARIASTLRLSPAQYLNCKQTLILASRAYLANPDGKQFRKSDAQKLCRIDVNKTSRLWEVFAKIGWLAGITEKDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N673</accession>
    <name>A0A9P6N673_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Endoribonuclease YSH1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Endoribonuclease ysh1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8 10">mRNA 3'-end-processing protein YSH1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">CPSF3</name>
        <name evidence="15" type="ORF">BGZ80_005476</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000027">
        <property type="protein sequence ID" value="KAG0024170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N673"/>
    <dbReference type="OrthoDB" id="10249535at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005847">
        <property type="term" value="C:mRNA cleavage and polyadenylation specificity factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004534">
        <property type="term" value="F:5'-3' RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:RNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006398">
        <property type="term" value="P:mRNA 3'-end processing by stem-loop binding and cleavage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16292">
        <property type="entry name" value="CPSF3-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10890:FF:000001">
        <property type="entry name" value="Cleavage and polyadenylation specificity factor subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022712">
        <property type="entry name" value="Beta_Casp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021718">
        <property type="entry name" value="CPSF73-100_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050698">
        <property type="entry name" value="MBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011108">
        <property type="entry name" value="RMMBL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11203">
        <property type="entry name" value="CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11203:SF11">
        <property type="entry name" value="CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10996">
        <property type="entry name" value="Beta-Casp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11718">
        <property type="entry name" value="CPSF73-100_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16661">
        <property type="entry name" value="Lactamase_B_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07521">
        <property type="entry name" value="RMMBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01027">
        <property type="entry name" value="Beta-Casp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01098">
        <property type="entry name" value="CPSF73-100_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="12">
        <location>
            <begin position="30"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-Casp" evidence="13">
        <location>
            <begin position="253"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="domain" description="Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term" evidence="14">
        <location>
            <begin position="483"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="604"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="613"/>
            <end position="625"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00069466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00075008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM01027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM01098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0024170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="719" mass="81153" checksum="DB9FB4E1BD672632" modified="2023-09-13" version="1">MAYKRKADLPVGDVNDLMEVTPLGAGSEVGRSCHVLKYKGKTVLLDCGIHPGQGGISGLPFFDEVDPASIDVLLITHFHLDHAAGLPYFTERTSFKGRVFMTHPTKAIFKWLLSDYVKVSNVGSNEMLYDEAQLAACYEKIETVDYHQEMNVDGIKFTGYNAGHVLGAAMFLIEIAGIKILYTGDYSREEDRHLMAAEKPTNVQTDVLICESTYGVQSHEPRIDRERRFTSTVHDIVQRGGRCLLPVFALGQAQELLLMLDEYWAAHPELESIPVYYASSLAKKCMTVYQTYINMMNSKIRKQFAVSNPFVFKHISHLKNMDMFDDTGPCVMMASPGMLQNGLSRELFERWCTDKKNGLLITGYCVENTLAKDVMNEPDEIQTMNGQKLKLRMSVDYISFSAHVDYTQNSAFIDEVKAPYVILVHGETNAMGRLKSALMSKYSERDEDIHIFTPKNTETVKLYFRGEKLARTIGQMAATFPEKDKLVSGVLVIKEFQYTIMDTSDLEEFVGLQTTSIVQRQVVPYHASFSLLKYHLRQMFGKIQELDCDINKLERVRIFDTVDVKEYNANHVLLEWTGNSVNDMVADSVLAVILNIESSPASVKLTKSDHTHSHAHGQPHNHSHGHASSSKADNSEWGNDIPLVERDLSDEFQDLVMFFASQFGAENVEQHEKTRTIEITMDGVQATVDCVQFQVKCEADALRHRAQNVLERAVRTCVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N6L6</accession>
    <name>A0A9P6N6L6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_004274</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000022">
        <property type="protein sequence ID" value="KAG0024312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N6L6"/>
    <dbReference type="OrthoDB" id="10280266at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0024312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="211" mass="23962" checksum="B41A8317C2ADFFD0" modified="2023-09-13" version="1">MVLFEASILPQFSHSTSKAIKNTTNPTKMTRSLLSLLVAVLALVTFVQAAFPTGLRRIHRHGEVLTALNKAVNAPVNIIPGKSQGQASWEIIETKNRHMVHIYQVDSGLFLSPQDPQDPMPYSPLVLSPFPQEWKLVKCDRCRNEDEDMYFIELGEKVDGKIMVLGNSRIHVYPPMAGLVPKEEGSKKQLWELDSSDDREYRSQRVFSQWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SQ54</accession>
    <name>A0A9P6SQ54_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_009194</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010005297">
        <property type="protein sequence ID" value="KAF9991355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SQ54"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9991355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="155" mass="16307" checksum="E8E6307E38AD0A17" modified="2023-09-13" version="1" fragment="single">VPSSMLRRVFASAARPSLSASVTFLPPRTVASLFPSPSSGSWSPAKSPLRSRSVVSLPSGPLVPPSPPSLRISLTAAPTPFTPCLSSLWLLPLSSMSLNSPRPTKRALASKSTGIPLSRTPWISLLSSPTLLVASTKTSSERVPRLPLSILTRIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SR35</accession>
    <name>A0A9P6SR35_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008739</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004845">
        <property type="protein sequence ID" value="KAF9992056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SR35"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.920.10">
        <property type="entry name" value="Pyruvate-ferredoxin oxidoreductase, PFOR, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050722">
        <property type="entry name" value="Pyruvate:ferred/Flavod_OxRd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002869">
        <property type="entry name" value="Pyrv_flavodox_OxRed_cen"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32154">
        <property type="entry name" value="PYRUVATE-FLAVODOXIN OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32154:SF0">
        <property type="entry name" value="PYRUVATE-FLAVODOXIN OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53323">
        <property type="entry name" value="Pyruvate-ferredoxin oxidoreductase, PFOR, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9992056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="184" mass="19868" checksum="7ED00A424432904B" modified="2023-09-13" version="1" fragment="single">IVQQAIGSKAPLDLGSVIADTEQPQEDVSQAIFWETASSSAVSAHVAKHIQAVLGHRIRHSSRVNSYRHKAVIETRLQFSKSTTIEFTEPALADYATVQDVSVLAEYNVVDSLKQGAVLVLNAPWSVEELETKTSAAFRFALGAKQIQVLLIDLNLVSKELGLSGAGKTLLGQITFSKTHSSNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SRA5</accession>
    <name>A0A9P6SRA5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_008450</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004589">
        <property type="protein sequence ID" value="KAF9992677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SRA5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9992677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="262" mass="29934" checksum="85EEB47ECC9C70E5" modified="2023-09-13" version="1" fragment="single">APCQHNPAFRLGVCQRLGEISANPIWYLKIRKCAVEFLRQLYKDDANNDQQVNINQWILYILSRLAESSKDIIEGPAQELLQEAQSNVSYVKGAVLHDRKNDILVLYSIMVTPPSTESPLLGCVQNKPDVETPLRKLRRERLKDRGGDVYISPRTKATQRATDHFDLTTKVQEFLASDSKVFLVLGDSGAGKSTFNRALEISLWDNYKTNGRIPLFIRLPAIENPEHDLIDKHLHKAKFTEAQIFELKAHREFIMICDGYDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SS23</accession>
    <name>A0A9P6SS23_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Condensation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007840</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004097">
        <property type="protein sequence ID" value="KAF9994328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SS23"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043041">
        <property type="term" value="P:amino acid activation for nonribosomal peptide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19544">
        <property type="entry name" value="E-C_NRPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensation_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF1">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Condensation" evidence="1">
        <location>
            <begin position="24"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9994328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="426" mass="47482" checksum="1F85BE5B290EAB8B" modified="2023-09-13" version="1" fragment="single">MAAKGDPYLLVVKMVFDTRDVFDRYIEAVQKVVDRHDILRTAIMWENLTTPAQVVLRRAVMSVTELSLDSADGPIVDQMMKLTDPREHRMDLTRAPLIRFVFAQDVDGRYIVFELSHHSIGDHSTLELMADEICAFYNGSDAKLAPPMPYRNLIAQIRSGPSAEVHEQFFTKMLAEIDTPALPYELSNVHHDGMDVTESHLELPQDLNTKLRGHAKRMGVSLASLCHLAWAQVVSKTSGQERVVFGTVLFGRMQGGSGSDKVMGLFINTLPIRIDVGEVSVDESVLKTQIDLAALLEHEHASLALAQRCSSVSPGTPLFSSILNYRHNVDGASEMYHIEGINTLDGQERTNYPFTISIEDGGSTLGLTAQVVEQFDAYRVCEYMQHALQNLSDALDHKLGMQVRCLEIIPATEREMLIQSWNATDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SS45</accession>
    <name>A0A9P6SS45_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BGZ80_007411</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the krueppel C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003790">
        <property type="protein sequence ID" value="KAF9995813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SS45"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000621">
        <property type="entry name" value="FLT3-interacting zinc finger 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000188">
        <property type="entry name" value="Zinc finger protein 787"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24394">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24394:SF44">
        <property type="entry name" value="ZINC FINGER PROTEIN 271-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="126"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="154"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="182"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAF9995813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="271" mass="30468" checksum="07E77104C44F3149" modified="2023-09-13" version="1">MAVQINGTTTSCGDNDSIEGTDDDDHEIRKQFYEASCLSPSTPPLSPQSIDYNGQGGLSRFHVPSFSNGPHYANDLGNGGHTFGDAANVPCSVRKIKAEEEVDENKKRTSIKKVKEEGNDSELRPFQCEFCQKDFRRQYNLNAHLKTHLEERIHACNECPKTFLRPYDLSRHQRIHTLDKPYKCRICSQIFIRNDAIWRHYRKAHKGHPEVPTSRRDKKKHIGSSNVGALVTRVVSAAASNSRAKSASRKAKSKAMMAATLNTKLTDNTQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SS53</accession>
    <name>A0A9P6SS53_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">chitin synthase</fullName>
            <ecNumber evidence="2">2.4.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">CHS1_4</name>
        <name evidence="10" type="ORF">BGZ80_007322</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.16" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010003724">
        <property type="protein sequence ID" value="KAF9996179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SS53"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030428">
        <property type="term" value="C:cell septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004100">
        <property type="term" value="F:chitin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006031">
        <property type="term" value="P:chitin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004835">
        <property type="entry name" value="Chitin_synth"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914:SF9">
        <property type="entry name" value="CHITIN SYNTHASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="173"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="204"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9996179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="234" mass="26187" checksum="50394A80178722BE" modified="2023-09-13" version="1">MGYMLFGAGYMTVAGIEAVGEEIKENGSGQSTVAGYLSNDMFRNTVISLASTYGLYFLASFIFFEPWHMFHSFLQYLFMVPSYVNILNVYAFCNIHDISWGTKGDTSVATDLGVAKKTAEGGVEVAVPTDSQDINNAYEEALTSLSVKTVEVKQHRDAKTKQEDYYREIRTRVLLTWIMSNALLVSLVTSIGNFDKNSKTYLGIVLWSVAFLALFRFIGSVTYMILRLFNGRLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ST28</accession>
    <name>A0A9P6ST28_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006697</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003310">
        <property type="protein sequence ID" value="KAF9998914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ST28"/>
    <dbReference type="OrthoDB" id="2414619at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9998914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="273" mass="28276" checksum="64F706E579B0183F" modified="2023-09-13" version="1">MSHQRASSTSSISTAFDTHINSNNQNLKRGMANPAGNSSTPVATPPSPLSVSIPRQRSFSSSLSSRGAFTGSSIIANPSNGFLNSPSVGATTPFSAAFNGPLASPTSASFSSATTTPTNTTTASSSLPTSQTAPVLHRRFSSSFNQLNQIVGSPSSTQIPDRGRRASLFGGSSPPMTPLTPTTQSSNEGNTKPGLFRKFSSSGRSAAATGQHPFDKNDVGPANVVPQPNGGHHQISTANAHLSPIDKLKPSQDKHSRSSSPMRSMILNGQMLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6STL9</accession>
    <name>A0A9P6STL9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006114</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003003">
        <property type="protein sequence ID" value="KAG0001813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6STL9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040309261" evidence="1">
        <location>
            <begin position="17"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0001813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="367" mass="39138" checksum="FD61242C06A8162F" modified="2023-09-13" version="1">MTTAATLRITIALALAALISQAAPCDIGGTSDIGTATDMGFNDLGTPVSLQSVNSGSTSLGSTVNAIPITNVNPINRYQPVIQAFAPIVQSECYGDYDGSILGPDYGWGSQLYRRDSGLSDTSSYSTLNAPYSSPLDSSSSDYGMGLWGQGQSDCDTSVPSQNVDLGSSVSVIPSTQVAPSTFYQPHVSSLESNIQAASAQSNYLPQQDVDLGSNVSIQPTTQVLPQTTYQLGVHQLTTSIEAASQDDQSLPQSSVQLGSNVLITPTVDLVVRTLVDLHPTPPSLIICHHPMGCTEARPMDLVQMTKTILKIIKVKIAKAIQLINATKITKTRLVYLTLAIRAITKARRPMDLSLMFLQIKDDFKNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6STX1</accession>
    <name>A0A9P6STX1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CMP/dCMP-type deaminase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_005900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytidine and deoxycytidylate deaminase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002903">
        <property type="protein sequence ID" value="KAG0002890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6STX1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004126">
        <property type="term" value="F:cytidine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055086">
        <property type="term" value="P:nucleobase-containing small molecule metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072527">
        <property type="term" value="P:pyrimidine-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01283">
        <property type="entry name" value="cytidine_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050202">
        <property type="entry name" value="Cyt/Deoxycyt_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004064">
        <property type="entry name" value="PRK05578.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11644">
        <property type="entry name" value="CYTIDINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11644:SF2">
        <property type="entry name" value="CYTIDINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0002890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="103" mass="11430" checksum="D1936870B9459FF1" modified="2023-09-13" version="1" fragment="single">LRTVDGKTYQGCNVENASYGGAICAERTAFVKAVSEGHLRFVAIAVSCDFNHFITPCGICRQFMNEFGKNLEIFFVNDDRTYKHAVLADLLPYAFGPEDMPGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SVD0</accession>
    <name>A0A9P6SVD0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Band 7 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_005160</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the band 7/mec-2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002560">
        <property type="protein sequence ID" value="KAG0006741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SVD0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08829">
        <property type="entry name" value="SPFH_paraslipin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="entry name" value="Band 7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050710">
        <property type="entry name" value="Band7/mec-2_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032435">
        <property type="entry name" value="STML2-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43327">
        <property type="entry name" value="STOMATIN-LIKE PROTEIN 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43327:SF10">
        <property type="entry name" value="STOMATIN-LIKE PROTEIN 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16200">
        <property type="entry name" value="Band_7_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="Band 7/SPFH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Band 7" evidence="2">
        <location>
            <begin position="62"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0006741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="322" mass="34943" checksum="FA390A3042783A77" modified="2023-09-13" version="1" fragment="single">MLRALPKFSQLSAAAPNSALLRTVHVGLPTSSAIVLRRSYATHPEKTNGSWGGSRKTLPANTIIKFVPQQEAWIVERMGRYHATLEPGLQVLMPFLDRIKYVQSLKEVAIEIPSQSAITQDPYKASYGVENAQFSVSQLAQTTMRAEIGQLTLDRTLAERAYLNANIVEAINVAAADWGIQCLRYEIRDIHPPDKVVQSMHQQVSAERTKRAQILDSEGSRQAAINVAEGLKQSTILQSEADKAEQINKASGEAEAILLRAQANAEGIRRIAEAIASTPGGHHAVSLTVADKYVDAFAQLAKETNTLILPANASDAAGMVAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SW31</accession>
    <name>A0A9P6SW31_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">KRR1 small subunit processome component</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">KRR-R motif-containing protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">MIS3</name>
        <name evidence="14" type="ORF">BGZ80_004151</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. Essential for vegetative growth.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Component of the ribosomal small subunit (SSU) processome composed of at least 40 protein subunits and snoRNA U3. Interacts with snoRNA U3. Interacts with MPP10, KRI1 and with ribosomal proteins RPS1A, RPS4A, RPS4B, RPS8A, RPS8B, RPS11A, RPS11B, RPS13, RPS24, RPS25, RPL4A, RPL7B, RPL8, RPL23, RPL25 and RPL28.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
            <location evidence="1 11">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the KRR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002147">
        <property type="protein sequence ID" value="KAG0007855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SW31"/>
    <dbReference type="OrthoDB" id="441223at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd22393">
        <property type="entry name" value="KH-I_KRR1_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22394">
        <property type="entry name" value="KH-I_KRR1_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1370.10:FF:000011">
        <property type="entry name" value="KRR1 small subunit processome component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1370.10:FF:000014">
        <property type="entry name" value="KRR1 small subunit processome component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041174">
        <property type="entry name" value="KRR1-like_KH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048550">
        <property type="entry name" value="KRR1-like_KH1_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048548">
        <property type="entry name" value="KRR1-like_KH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048549">
        <property type="entry name" value="KRR1-like_KH2_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024166">
        <property type="entry name" value="rRNA_assembly_KRR1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12581">
        <property type="entry name" value="HIV-1 REV BINDING PROTEIN 2, 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12581:SF0">
        <property type="entry name" value="KRR1 SMALL SUBUNIT PROCESSOME COMPONENT HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17903">
        <property type="entry name" value="KH_KRR1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21800">
        <property type="entry name" value="KH_KRR1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006515">
        <property type="entry name" value="KRR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 11" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="6 11" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 11" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="K Homology" evidence="13">
        <location>
            <begin position="146"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="250"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="24"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="250"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="294"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR006515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0007855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="343" mass="40020" checksum="E6CBADB43D3B6894" modified="2023-09-13" version="1">MSAEPAESTFQEDQPGVEQEVTQRKGKQGKYRRDKPWDTDDIDHWKVEEFKPEYNPAPFTEESSFATLFPKYRENYLREVWSHVTRALEKVGIACVLDLVEGSMTVKTTRKTWDPYMILKARDLIKLLARSVPLPQALKILEDGIACDIVKIGNIVRNKERFVKRRQRLLGPNGSTLKAMELLTQCYIMVQGNTVSCMGPYKGLKEVRRIIIDCMNNIHPIYHIKELMIKRELAKDPKLAEESWDRFLPHFKKKNTKPQKKKVSKKDKKDYTPFPPAQTPSKIDLQLESGEYFMKPKEKEARALEKKKEEQKENSLKRQAERELAYVPPVEDTPKKKKKKAEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SW80</accession>
    <name>A0A9P6SW80_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_004641</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002345">
        <property type="protein sequence ID" value="KAG0007453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SW80"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0007453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="108" mass="12351" checksum="323EF0052F65E862" modified="2023-09-13" version="1">MSLDYYDFLIGMDTFYRLGFSIGGIELPSNNDEACEDYEIEKEQPSLFPNTPTNEESSPEFQELKKSFLDKIKVLLDNNAKIDPKSHCPLDIMKVVLDVKNVATLKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWE0</accession>
    <name>A0A9P6SWE0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Crinkler effector protein N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_003913</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Host cell</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002066">
        <property type="protein sequence ID" value="KAG0008054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWE0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043657">
        <property type="term" value="C:host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045379">
        <property type="entry name" value="Crinkler_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20147">
        <property type="entry name" value="Crinkler"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Crinkler effector protein N-terminal" evidence="4">
        <location>
            <begin position="5"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF20147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0008054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="331" mass="36372" checksum="3AF5F8C4DA1983EE" modified="2023-09-13" version="1" fragment="single">MTSVIKLFCILNGDSSSFSVTIPLDASVGDLKDAVKEKKNPRSDDYAADELALFQISVLSSRKRQIILSNYTKELDDPTSDISEVFGTAPAKRTIHVIVQRPSADTTISHPAVPSPLSPISRTTSPSATPFSSIFIPQGKIEVELVDILKGINYNHVRTAHPKEVEASQREKLGRFYKRPLPYNETAEDISLVMLELELDKQAKTSEGETLREIIDSDVGKYNDHRVVAMVAPSGSGKTATVVDLASRHFVIYAVCCIPSPTVSPGFKDPNFMNLSKDVESIYAGIINGELGSTRDPVDINNEVKSLVGDRVDVEFLARLLFLQHLLWCIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWG5</accession>
    <name>A0A9P6SWG5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Elongation of fatty acids protein</fullName>
            <ecNumber evidence="10">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_003803</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>an acyl-CoA + malonyl-CoA + H(+) = a 3-oxoacyl-CoA + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:50252"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:50253"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the ELO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="10"/>
    <dbReference type="EMBL" id="JAAAID010002022">
        <property type="protein sequence ID" value="KAG0008152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWG5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009922">
        <property type="term" value="F:fatty acid elongase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034625">
        <property type="term" value="P:fatty acid elongation, monounsaturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034626">
        <property type="term" value="P:fatty acid elongation, polyunsaturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019367">
        <property type="term" value="P:fatty acid elongation, saturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030148">
        <property type="term" value="P:sphingolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042761">
        <property type="term" value="P:very long-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002076">
        <property type="entry name" value="ELO_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157:SF169">
        <property type="entry name" value="ELONGATION OF FATTY ACIDS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157">
        <property type="entry name" value="FATTY ACID ACYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01151">
        <property type="entry name" value="ELO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5 10" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7 10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="49"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="208"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="241"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="276"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0008152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="320" mass="36668" checksum="E940106CF59C4AEF" modified="2023-09-13" version="1">MAQILKDLGSKYLSLNFEDDRRIFLNTDNWAIAPQPKGILFPEYHDVLINWRTPFTVAALYVLMVVLLNPKQGKVSRVVAADNAAKEAGSAKKQKEELSQSTPFITALVFVHNTILCVYSAWTFYGMFFAWRKALATHTFMDAVCDTDGTFWDSLGYYSYYFYLSKYYEIVDTIIILLKGRRSSLLQTYHHAGAIITMYMGYNYRAHPIWIFTTFNSFVHTIMYAYYAATSVGLKPPGKKYLTSMQITQFWTGVLLAFWYQLGAPEGCFSNPGSRFAIWTVLFYVFPLIYLFMAFASKMYGDRNKRIKAASADAKAKKAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWT4</accession>
    <name>A0A9P6SWT4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_003654</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001984">
        <property type="protein sequence ID" value="KAG0008252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWT4"/>
    <dbReference type="OrthoDB" id="2415345at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0008252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="116" mass="13491" checksum="8E7363E49DA47ACA" modified="2023-09-13" version="1">MTSLTPNPPMEEVDYEGALHFLFSIAKHNPAAKELCNEIDLPMTPPIEAGILQYLFRLQAIGRIEDWPLLFGYGNSFILHLLEKMSKAEVLNDSENERMIWDLRRKETTDWLMIKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SX42</accession>
    <name>A0A9P6SX42_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Arrestin-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_003173</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001823">
        <property type="protein sequence ID" value="KAG0008682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SX42"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011021">
        <property type="entry name" value="Arrestin-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00339">
        <property type="entry name" value="Arrestin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin-like N-terminal" evidence="2">
        <location>
            <begin position="103"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="253"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="80"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0008682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="624" mass="68069" checksum="3704C5CC1FD945B8" modified="2023-09-13" version="1">MATMKIQLEDNYFVLPYTAPALQALRLQDNEAPANSVPGSPSSSMTMTSPERTLSFGAVSVASTLPSSAASVRSSFEIEQQQQQQQQQQSVSDSSSSSTTTSLKGKLLLTLPKPTKVASLAISLNGSTHIAFLGTGKRSHYSRHHIRSQQFLIEPRPDSEQYTLLGGNDGNNNNNKEFVLEFPFSIEVPNHLPASVTTPQGGTIYRLTAVLTLAKSAGIMSFLSTSSTITASTPVQIYRAPRPRYLSLEDAAAFEGEGEEEEGEEGEEHASKPGQERGVTRTEPRDLADGDELMPATVHHIWPGQVETTVVIPFTQLPSQSKPDLRIRVRVLRENLAIKSFQAALWERAIFRVQKAGAPANSKKYTIGVRERVVSAQRCDAGWVNDAITTQLPHTFEKVVLFSIPNAVRSHNELYSSRICNVSTFTSASKLKKRHLKVDRELKDSEFGEVSIEIQHFIRYSLFVTGSVDLKGKTITTPVERYIGDVPVIVRGMPSGPECDRTGLPTYLYSFSTSRVSYEEAQDYEIEAAGMAGGDEALFAGYDGTGPIYGDYENDDALMALMGYRGSRTPPSYEDTVGSPSLDTSISDLQNMHISTMVPTTTVTHGLGIRGGNNGSNNALGLTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SY16</accession>
    <name>A0A9P6SY16_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_001008</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001221">
        <property type="protein sequence ID" value="KAG0011031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SY16"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000054">
        <property type="term" value="P:ribosomal subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01857">
        <property type="entry name" value="HSR1_MMR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043358">
        <property type="entry name" value="GNL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45709:SF2">
        <property type="entry name" value="LARGE SUBUNIT GTPASE 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45709">
        <property type="entry name" value="LARGE SUBUNIT GTPASE 1 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G" evidence="6">
        <location>
            <begin position="402"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="267"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="689"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="273"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="290"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="321"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="359"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="691"/>
            <end position="702"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0011031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="710" mass="80140" checksum="34E9242E7C435FFB" modified="2023-09-13" version="1">MPLPKSKKNVGLGNAIIKARFQGRSRPRDGDERLHSADVDDGASWTRLQSVTQEGDLESFLSTAELAGTEFTAEKLNIKVISNQYENPFMLSADKEKETLAKHKEFKSELTVPRRPHWDSNTTASELQRMERQSFLDWRRSLATLAERESLLLTPFERNLEVWRQLWRVIERSHLIVQIVDARNPLFFRSTDLETYVKEVDPRKKNLLLINKADYLTVKQRKRWADYFDSEGIHYTFFSAALAKERQEKEQAERDRIEQLAQELAELKAENSDYSEEEEEEDEDAEEEKEAEKTPVAEAEKAVETSSVPSNEETKVQKQEQEEEEEEEEEEEEEEEEEEESDQEEDSKKPNKTHSHWKAIKETEKDDERTRIRDTKELYELLLKETPIINDPRDPLNGIMSIGLVGYPNVGKSSTINALLGEHAVSVSSTPGKTKHFQTIHLTPKMILCDCPGLVFPSFATTQGDMVCNGVLPIDQLREFTGSVGLIGKRIPKEVLEAIYGIKIAVLSEEEGGTGVPTAEEFLIAYAVARGFTKAGQGNPDESRAARYILKDYVNGKLLYCTPPPGFEPLEFNQEHNQLDRFKKRKQLPTRRLPASASTYINMNAVTPLSHTGSGTGKTAAIDNTFFTPARSTAYLPKITGKTAIDVSGGISRVQLYPHQKNTDNQGYVSRKMRSQAGQADVEGVAGALGSKKHKKGKKNVKQRSGGGLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SY67</accession>
    <name>A0A9P6SY67_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_000836</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001184">
        <property type="protein sequence ID" value="KAG0011231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SY67"/>
    <dbReference type="OrthoDB" id="2369256at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="3">
        <location>
            <begin position="25"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="213"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="440"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0011231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="515" mass="58807" checksum="C02D832487305412" modified="2023-09-13" version="1">METNVAAAEPPPTQAITPITATAIPEVTSIIASYLTKKDLSSCTLVCRTWCIAYTPLIWKTLNTRIPTPKNASLLPGLLAKNGRYIRSLTITDLPETYTDNPNPSTELVFDCPAVQNIVHLTINTEREKKQAMKNIIYHSRHTLRFLRLNFKMDKSKKPAGWRGEPWLGFPDMVPYLHSIFLDNWNMTRQELIALLKACPNLKVLSFSSTFLDQEPPPTSTTAKDQESLSDDSDGSLDRPETKDTFQHFGIRNFRMCSKLYHVLDLMPNIEILEFYRFDRSIEGQELERFCQTIKEHCKRLNQIWAFGFECSMLPPVLESLSQLVAYRGCSDIETELSILDHANSLEEANLSDYTERNFLPLKFMESCPRLRSFITGHSSTTMNEVQGSLRRGWACQNLQELRLFIFKLSPALIEAIMQDLGAERETDSRTRTRRSAVWIASQLEQRQQMQAAMNALTREQRDFQDEFSRFLRGFRKLTRLNFGTGWYSISRSKVVSSSTVSATADPSALGVVKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYP2</accession>
    <name>A0A9P6SYP2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Chromate ion transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_000136</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001021">
        <property type="protein sequence ID" value="KAG0012204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYP2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015109">
        <property type="term" value="F:chromate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014047">
        <property type="entry name" value="Chr_Tranpt_l_chain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003370">
        <property type="entry name" value="Chromate_transpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33567">
        <property type="entry name" value="CHROMATE ION TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33567:SF3">
        <property type="entry name" value="CHROMATE ION TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02417">
        <property type="entry name" value="Chromate_transp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004810">
        <property type="entry name" value="ChrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="106"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="162"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="280"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="317"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="350"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="389"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="421"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="453"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="190"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="190"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0012204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="491" mass="52871" checksum="4196A0DF5E253E40" modified="2023-09-13" version="1">MTTMPNSSNPYNLPPLKDRLKETFYTYFKFGYTTFGGPSAHIAILYDDIVTKRKWISSEQFTELFAICQALPGPASTELAYSLIPGAIVMTVAGVLIGNIKGTIPLWATRLEQGLASAAIGLVALAAYRMSTALATDKLTRILALVAGSVSVLYTAPWLLPVMMIVGGITSYIYDAFLTPFVDNWKKKREQQNDAEKAGEKDLEQGIIEPSDSPDSGNTRGGEESDTIQVQSAETNAEKALSVNGSIRSRGKNEPATPMESLEDIKMDTTRKAFSYTKKLGLVFFLIFLALLIAAILARALIPVSEKATYGQLVSTFYFVGSIIFGGGPVIIPLLKTYTVDSHWMTDQQFLVGLAIIQSLPGPNFNFACFLGAVAMVNANQSGVAGATLGYLAIFFPGLILKNAIIPFWQYVREHPSVKMVFRGVNACALGLVFSATWLLWIQTNSMGGNSGYHAVIASAAFVAAGYLDIPSPLVIVLGGGMGAIEYAVSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYU0</accession>
    <name>A0A9P6SYU0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Galactose oxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_000094</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001012">
        <property type="protein sequence ID" value="KAG0012259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYU0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093:SF18">
        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00612">
        <property type="entry name" value="Kelch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040125060" description="Galactose oxidase" evidence="5">
        <location>
            <begin position="32"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="359"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="517"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="518"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0012259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="557" mass="59268" checksum="771A34A250F579CD" modified="2023-09-13" version="1">MNANKTTTPWRKRLSLAKALALVALISVTHAQSPPVSSRRMGFTMLDDTLYIEGGFDTDTSSQFNALDLSTSWSTDSPAWRNLKSGQSTSHLALTPISSASNGGAKGSLMAIGGMESPAFYSMFDIDAGTWTNLTIKAPYVSLEGQSAVSDPNTGLIYILGGVGINNTVYNQLTVYDPKAKNTVSQQTSSAAASIIDQGAVWSTTRNTIITFGGTRAPPADPKGLGTGDLNEYDPSSKSWKIMSTTGDIPPSRLDHCMAASSDGSKIVVFGGTAGDSTYFNTIYILDVKSGKWKQGQSAPVARTRMSCAFHSYQFIAWGGSSGANRATMLNNLPVVYNLNKNSWTDNYNADEVEKKTPVGAIVGVIFGVLIVAGGGFFFYKRQQRKKQENDAYYNDAVAAAAVTSCEDDNVKVLADEIYIGYDNSSGFSGYGNEYPLSNVSTGSPLGSEKYGNSYSPSTNPYSPSPTYYGGALIGTPIIQSPSAAFVAHQNPFVSPEDYYPPASNIQNPYQQYQQPSATNYAGSQSPSTGARSPQVIPDSTTTTTTTSGGYIPPPPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYW0</accession>
    <name>A0A9P6SYW0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Tyrosine aminotransferase</fullName>
            <ecNumber evidence="5">2.6.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">L-tyrosine:2-oxoglutarate aminotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BGZ80_000197</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-tyrosine + 2-oxoglutarate = 3-(4-hydroxyphenyl)pyruvate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:15093"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:36242"/>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
            <dbReference type="EC" id="2.6.1.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 14 15">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid degradation; L-phenylalanine degradation; acetoacetate and fumarate from L-phenylalanine: step 2/6.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.5" evidence="5"/>
    <dbReference type="EMBL" id="JAAAID010001034">
        <property type="protein sequence ID" value="KAG0012105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYW0"/>
    <dbReference type="OrthoDB" id="7042322at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004838">
        <property type="term" value="F:L-tyrosine-2-oxoglutarate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006559">
        <property type="term" value="P:L-phenylalanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006572">
        <property type="term" value="P:L-tyrosine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000048">
        <property type="entry name" value="tyrosine aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005958">
        <property type="entry name" value="TyrNic_aminoTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005957">
        <property type="entry name" value="Tyrosine_aminoTrfase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01264">
        <property type="entry name" value="tyr_amTase_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01265">
        <property type="entry name" value="tyr_nico_aTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45744">
        <property type="entry name" value="TYROSINE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45744:SF2">
        <property type="entry name" value="TYROSINE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000517">
        <property type="entry name" value="Tyr_transaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="11" id="KW-0585">Phenylalanine catabolism</keyword>
    <keyword evidence="10 14" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0828">Tyrosine catabolism</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="16">
        <location>
            <begin position="43"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="15">
        <location>
            <position position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00015959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00031696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRNR" id="PIRNR000517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR000517-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0012105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="414" mass="45766" checksum="670C954C1ABB2871" modified="2023-09-13" version="1">MSASNTSPRKAWKVNASIVAKRTSNPIRAIVDHIKVKPNANKSMISLALGDPTLFGNFKIHESCTEAVSKQLHSYKSNGYPPSTGYLEARQTVAEKFTIPEAPLTAQDVIVTSGCSGAIDMCIGVLCNEGDNILLPRPGFSLYQTVADSKGVEVRYYDLLPEHNWEMDLKQLESLIDDRTATVVMNNPSNPCGSVFRKQHLLDFLAVCERNHLPVIADEIYCDLVFSGNEFFPLASLTKTVPVLSVGGLAKKYLVPGWRLGWIFIHDRNNIFDAEVRDGLNSLSQLILGPNSLIQASLKDILHNTDPAFHTETCAQLEANAKLSTDILSKIPGLKVIVPQGAMYVMIAINVQEFKDITNDIVFTEKLLGEESVMCLPGSVFQCPNFIRIVFTSPPNILEEAYNRMAEFCARHHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZ71</accession>
    <name>A0A9P6SZ71_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_011371</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000906">
        <property type="protein sequence ID" value="KAG0012992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZ71"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="224"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="234"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0012992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="243" mass="26940" checksum="7BE8092D4DBE6E4A" modified="2023-09-13" version="1" fragment="single">MIHTDLSKTGFVDSISPRSGLMPPSAEILSRSCHEDIQSVLEILGIISYPSLQVHATNGQEQSLDSPVSVEESDEPHQLGHGKDSSSSSLNTKQQRRYDAVAIDIQAALTVTEMLSVLEQESRIHDNDGNYIHPEDCCYARLSFGDLEEQRSEMKKYLTIVQEQIFKPQVETSKTQLEQLLIANSAPGSSALPKWMYDNEGTSGTSGESSLDRCHAFLEFFRSDTRNSLPSPSDNKDGFLDDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZ84</accession>
    <name>A0A9P6SZ84_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Alpha-type protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_011507</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000933">
        <property type="protein sequence ID" value="KAG0012795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZ84"/>
    <dbReference type="OrthoDB" id="2871286at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.200.10">
        <property type="entry name" value="MHCK/EF2 kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004166">
        <property type="entry name" value="a-kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051852">
        <property type="entry name" value="Alpha-type_PK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45992:SF11">
        <property type="entry name" value="ALPHA-TYPE PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45992">
        <property type="entry name" value="EUKARYOTIC ELONGATION FACTOR 2 KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02816">
        <property type="entry name" value="Alpha_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00811">
        <property type="entry name" value="Alpha_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51158">
        <property type="entry name" value="ALPHA_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Alpha-type protein kinase" evidence="6">
        <location>
            <begin position="1"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0012795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="236" mass="26873" checksum="319692400A784611" modified="2023-09-13" version="1">MAESRYNNSTSAAIDSSVEYARGAFKKVHKGEYTEGSRTGQPCVSKVFISGSVFEDSYFQHEMDVVKKATEIVRAFNGLELINKRIIINQPEIWVFRESRALTLIEPLIENFEKFNSNSGWTQDTTSWGQAMQALAHYSFHYSNGQLTLCDLQGGVYTDGIILTDPVVMSTDRRFGPTDLGKDGIDSFFHHHVCNNFCRSSWTRPTRRMRLFPVVKGTTMMEVKTQTGRNLLTQRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZT4</accession>
    <name>A0A9P6SZT4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Histone H2A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">HTA1_2</name>
        <name evidence="14" type="ORF">BGZ80_010533</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="10">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the histone H2A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000742">
        <property type="protein sequence ID" value="KAG0014282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZT4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00074">
        <property type="entry name" value="HFD_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000008">
        <property type="entry name" value="Histone H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002119">
        <property type="entry name" value="Histone_H2A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032454">
        <property type="entry name" value="Histone_H2A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032458">
        <property type="entry name" value="Histone_H2A_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23430">
        <property type="entry name" value="HISTONE H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16211">
        <property type="entry name" value="Histone_H2A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00620">
        <property type="entry name" value="HISTONEH2A"/>
    </dbReference>
    <dbReference type="SMART" id="SM00414">
        <property type="entry name" value="H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00046">
        <property type="entry name" value="HISTONE_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0007">Acetylation</keyword>
    <keyword evidence="4 10" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0488">Methylation</keyword>
    <keyword evidence="9 10" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="12">
        <location>
            <begin position="35"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="Histone H2A C-terminal" evidence="13">
        <location>
            <begin position="115"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="19"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="35"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF16211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0014282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="154" mass="16657" checksum="1C8384C5EA0FED7D" modified="2023-09-13" version="1" fragment="single">DYFSEKTYNNLHNTLKETTFTMSGGKSGGKSASAPKNSTSRSSKAGLQFPVGRIHRHLRKGNYAQRVGAGAPVYLAAVLEYLAAEILELAGNAARDNKKSRIIPRHLQLAIRNDEELNKLLGHVTIAQGGVLPNIHDSLLPKKTKKGGVASQEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0P2</accession>
    <name>A0A9P6T0P2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Vesicle trafficking between the ER and Golgi</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">SLY1</name>
        <name evidence="2" type="ORF">BGZ80_009217</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the STXBP/unc-18/SEC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000531">
        <property type="protein sequence ID" value="KAG0016471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0P2"/>
    <dbReference type="OrthoDB" id="10251230at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.830.10">
        <property type="entry name" value="Syntaxin Binding Protein 1, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043154">
        <property type="entry name" value="Sec-1-like_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043127">
        <property type="entry name" value="Sec-1-like_dom3a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001619">
        <property type="entry name" value="Sec1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027482">
        <property type="entry name" value="Sec1-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036045">
        <property type="entry name" value="Sec1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11679">
        <property type="entry name" value="VESICLE PROTEIN SORTING-ASSOCIATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00995">
        <property type="entry name" value="Sec1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005715">
        <property type="entry name" value="VPS45_Sec1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56815">
        <property type="entry name" value="Sec1/munc18-like (SM) proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0016471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="641" mass="71984" checksum="9A076C2EDA2985A8" modified="2023-09-13" version="1">MAQAPRDPTLREQQIAAIAAMLNLNKKPEPISQVDQVIPMASDAEWKVLVFDSFGRDVISSVLRVNDLRENGVTVHMLLKNERQPIPDVPAVYFVEPTSENIRRISEDLSNHLYDSYYINFSSVIPRPLMEEFAASTIPSGSSAQIQQVYDQYLNFICTEPNMFSLNDRQSYLALNDPTAPETAIEASIDKAASALFSVLATMGVIPIIRCPRRGAAEMLAKKLDGRLRDHVMNSRNNLFSDSNTVNFQRPVLVILDRNMDLVPILSHSWTYQALVHDVMDMKLNEIVVQTEENGRTVKKKYDIEAKDFFWNKNASAPFPQVAEEIDSELTKYKKDAAVISQMSGVNNLDDVSQLDFSSGAKHLKNAITALPELTARKATLDMHMNIATGLLQGIKDRQLDTLFQMEESITKQTKANIMEAINDPEKKVPEDKMRLFLIYYLSIQEDISNELMQEYEDALVKAGCDLAPLRYVKGIRAFTRMTNMTQQPPQSFGRPDYLLNRLGTIGNKLSDHLGSGGLGGGFENLLAGVKNFLPAKKDLPMTRIIESIMEPGGGANETNEDFLYFDPKVSRASNAKMPRTRTPFQEAIVFVVGGGNYVEYQNLNEYAQRQTIKKKITYGSTEVLNPKEFLQQLASLGKEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T169</accession>
    <name>A0A9P6T169_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FAS1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_008402</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000454">
        <property type="protein sequence ID" value="KAG0017322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T169"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.180.10:FF:000032">
        <property type="entry name" value="Fasciclin domain-containing protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.180.10">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050904">
        <property type="entry name" value="Adhesion/Biosynth-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036378">
        <property type="entry name" value="FAS1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000782">
        <property type="entry name" value="FAS1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900:SF124">
        <property type="entry name" value="FI05614P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900">
        <property type="entry name" value="PERIOSTIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02469">
        <property type="entry name" value="Fasciclin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00554">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82153">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50213">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040140446" description="FAS1 domain-containing protein" evidence="3">
        <location>
            <begin position="27"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="737"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="4">
        <location>
            <begin position="27"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="4">
        <location>
            <begin position="172"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="4">
        <location>
            <begin position="395"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="4">
        <location>
            <begin position="544"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="779"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="784"/>
            <end position="804"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0017322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="812" mass="88853" checksum="FB027863FDD95EE2" modified="2023-09-13" version="1">MKIQTNAARLLLLLTTLLFAATPVLATTKVIDLISSDASFSRLIKELQRLRLVVFLNDRKTCTFFAPTNAAFSKWDAANPGRRIDRGTLLYHILPDSVLTPDMRDAMLLETMYVREGYLGDHKEGQIAQVSKPIWRPGRKVQLLIGGAEILKNDWQADNGVVHVIDRLLTPPVDLADTIQKHAELSTIYNLIHSTGLDDLLHHHLPFTLFAPTTDALKKLNDIQVRYLRHDQGRKDLEITFHHHIHVGTIYIQDIQKGSSSISTLEGQELMVNLDDKLLVDNAEVEKKDIIAANGVIHKVSRPLLPSALVWTAGKYLVGLNATKFVDALREAGLSHYVDDPEAKLLNGRAQRSKVNVRREDKQAVILIDDVEIKGEPVQVGKSLVYLVARPLEPPIPLIKKIKKEQSLSVFAQALSATGLSRRLSDARGVTVFAPNAEAWTDLGVVTNYLMLNDSVARDALEAVARYTIVEDVIYTPDIKSGRTVLRTSQGSELVMEKSNGAIYVGEGRLERSLQVGGKITGKDTLVDSGVIQAVSAVALPPTLSITLFNVLQGAGTQDFLQAFQTSNITQILTNWEQDFTIFAPTDEAFRKAGLEGALNDKDFVARLVRLHVLPGKILNLEEDMGDDEASMLNTDARLSVRDIHGDGKNFGVRVKGARSRREANIIGSGRAHPAWPTDEYGRRPKVVNGMRQQNAADDDQDSYITSEMLAPQPSGVIYVIDRVLLPGDPEPLGGTWFWIAVISVGVLLTINLFAFSGFLLHALVKEIRQLEGYQPVAADEEAGAPASGDAAPASDDTAPASGDVAAAGGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2G2</accession>
    <name>A0A9P6T2G2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Queuine tRNA-ribosyltransferase accessory subunit 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Queuine tRNA-ribosyltransferase domain-containing protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">QTRTD1_2</name>
        <name evidence="8" type="ORF">BGZ80_004812</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Heterodimer of a catalytic subunit and an accessory subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000241">
        <property type="protein sequence ID" value="KAG0020086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2G2"/>
    <dbReference type="OrthoDB" id="27601at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008479">
        <property type="term" value="F:tRNA-guanosine(34) queuine transglycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.105">
        <property type="entry name" value="Queuine tRNA-ribosyltransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03043">
        <property type="entry name" value="QTRT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028592">
        <property type="entry name" value="QTRTD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050852">
        <property type="entry name" value="Queuine_tRNA-ribosyltrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036511">
        <property type="entry name" value="TGT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002616">
        <property type="entry name" value="tRNA_ribo_trans-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00449">
        <property type="entry name" value="tgt_general"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46064">
        <property type="entry name" value="QUEUINE TRNA-RIBOSYLTRANSFERASE ACCESSORY SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46064:SF1">
        <property type="entry name" value="QUEUINE TRNA-RIBOSYLTRANSFERASE ACCESSORY SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01702">
        <property type="entry name" value="TGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51713">
        <property type="entry name" value="tRNA-guanine transglycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="4 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="tRNA-guanine(15) transglycosylase-like" evidence="7">
        <location>
            <begin position="18"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="121"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="183"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="245"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="519"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="124"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="188"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="245"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="543"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="430"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="432"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="435"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="463"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0020086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="571" mass="64932" checksum="E9A6BE67C7F29619" modified="2023-09-13" version="1">MSPIKFEIHSSIREPNSNARTGTLSIVKASQPDQDAVKRVIETPGCFMFSIKGSVPHLTPDNMRLQDFGGVNVSLEQLLQMDQPASFASKWPSKSFTLADYLYLKDLILLCDMRDYSSLSSSLTPKTSQQDPHTQRISPNTDRHVNLSTLRGARPLTLDDYLSVVRQFRPDIMVALADNIVESSSRNNESKTEVDVKKEKNDGSRGKADEKRIRKSIDRTLKWLDQILLERQGRDGRIEDRRIEEEKKRKKEKEKIRQARKQEHGQQEQQGEEEVPVEIPEIETEPWEDVALFAHVQGGQFEEERIRSAEETSKREGVNGFIIDLGVYSNGDNSKEERLAHLKTSVDHLPAQKPRMVYGIQTPEDVLKVVALGVDLFDTSYPFILTEEGKASMYSFGPNSTSDETNNNNRWINLWDDEHGDKFVPILESCECYSCKGGKHTRAYINHLLKTHEMLATVLLMSHNLYQYSKFFSAVREAIKTGTLDQYTQDFERQFGVEPVRTGEKHKAQIVVEEALTKRNQRLEPTEPAVVDAIGSGDGDGQSFKRPDDDGGENEKEKKKQKKDSSEQSNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2M7</accession>
    <name>A0A9P6T2M7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cyclin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004341</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000222">
        <property type="protein sequence ID" value="KAG0020372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2M7"/>
    <dbReference type="OrthoDB" id="286814at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000307">
        <property type="term" value="C:cyclin-dependent protein kinase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20557">
        <property type="entry name" value="CYCLIN_ScPCL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013922">
        <property type="entry name" value="Cyclin_PHO80-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615:SF27">
        <property type="entry name" value="PHO85 CYCLIN CLG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08613">
        <property type="entry name" value="Cyclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="189"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="313"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="392"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="313"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="338"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="393"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0020372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="514" mass="56727" checksum="36557AB38535E5A2" modified="2023-09-13" version="1">MFRKFCLDVLSATLLSPSVILLSLKYIQQLMINLKESNKIVNTGDGAEYRFFTGALILANKFLDDNTFTNKTWADITGMKIKDVNHLEMQFLNGIDFRLFTSSHHYSEWLASLTQFTSVHMPSQHQVAYQQQAAAAQSPVSPMDHTNSFTESVSVRQHGSGSESRHSTQSLSMASISQYIDSVKHFQQKSTSSSRYQRVPSTAYNQTPASSTAHSSQQQFMSLPPPSQGPHSIQQVQSNLSPSTHTHAYQQEAQEPARRKRSAINAFDDSMERSPCYDLGSLPYSNHVPIRRQSHKRFSSSSSLATLMGISTGQDVFQSNGPSPSVQQQRHYQRSHRASSGSLSTPFRGQHQRSVSGSYYIDMTGYASNYGQESSQINLPMPNTFSRSGGIHPLERDQELGHRPPSRTDAYHAPLSMHQGSMATGGRSQAYHPSTPPQYSPNKCETTCHSSGCGSNISTGSTASYDVDPRLWGPLDSLSLYAITTQAAKRVVAQSKALSSSANGLHMYYPTTLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2P4</accession>
    <name>A0A9P6T2P4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_003985</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000209">
        <property type="protein sequence ID" value="KAG0020561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2P4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040317831" evidence="2">
        <location>
            <begin position="26"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="244"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0020561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="264" mass="26894" checksum="6FD95F07314F8DA3" modified="2023-09-13" version="1">MKSTFFVSTIAVVLGSFLLPSTTNAVVVDTCTLAIAGLTSDSGLNTCLPITKLSTLATSNITASLVDSTLAAFCPLPVCPSASITLVENTVKQSCVNSTDSSTSDLIAGVASLYTPAKEGLCQTVSSTNATYCATVLTQSMLNYWSTNPATTGVSIFTNSTALLAYVNAMPTSLLCTSCNKAIINPLVNYVSTNKTSLSSGILSWASVIESGVKSKCGSDFVNGAATTTPSTGSSSTSAALSGYNSPATTVFMVVLLSAVALLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2V2</accession>
    <name>A0A9P6T2V2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RWD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_003379</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the IMPACT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000189">
        <property type="protein sequence ID" value="KAG0020908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2V2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140469">
        <property type="term" value="P:GCN2-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006446">
        <property type="term" value="P:regulation of translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23821">
        <property type="entry name" value="RWD_IMPACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.30">
        <property type="entry name" value="Impact, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023582">
        <property type="entry name" value="Impact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001498">
        <property type="entry name" value="Impact_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036956">
        <property type="entry name" value="Impact_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006575">
        <property type="entry name" value="RWD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16301">
        <property type="entry name" value="IMPACT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16301:SF25">
        <property type="entry name" value="PROTEIN IMPACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01205">
        <property type="entry name" value="Impact_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05773">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00591">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50908">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0678">Repressor</keyword>
    <keyword evidence="6" id="KW-0346">Stress response</keyword>
    <keyword evidence="5" id="KW-0810">Translation regulation</keyword>
    <feature type="domain" description="RWD" evidence="8">
        <location>
            <begin position="9"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="156"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="373"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="57"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="156"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="167"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="191"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="211"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="384"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0020908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="396" mass="43532" checksum="7875D4C1FC7B0F7F" modified="2023-09-13" version="1">MDNTSALEEESLAIVSIYGPSSFYPLAGTATSPDSPPVYTLKVSLEDPNFDFDPASTDENQNNTGTGSSNFSRNRKELEFRIYFPEGYPETNSSAPVHEIVSIYYGTLRLTDSIIQEIDQGLDQCFVPGEVVVFSWIEWLRSFLEELEARIEKDGLHGNAKTGHDEDNVDQDSDGEENKDEDEDESHSSEAQRTASDYFSTDDSSQDPQGSAALSSSLASLSLLHSPASPSDNHSLRVPRVSGTPEFNIRSGPPIIDRKSVFVAHLAPITQPTQVPLMIQQLKQENKKVVKATHNIMAFRVENENGTISQDNDDDGETAAGSRLLHLMSILDVKNVVVVVSRWYGGIPLSADRFKHINNAARLLLDECGYIKPSTPEATSNANSKKKGHSKKAGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2Z8</accession>
    <name>A0A9P6T2Z8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Hemolysin-iii channel protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_003504</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000193">
        <property type="protein sequence ID" value="KAG0020834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2Z8"/>
    <dbReference type="OrthoDB" id="5585746at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038023">
        <property type="term" value="F:signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006882">
        <property type="term" value="P:intracellular zinc ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004254">
        <property type="entry name" value="AdipoR/HlyIII-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20855:SF97">
        <property type="entry name" value="ADIPOR-LIKE RECEPTOR IZH3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20855">
        <property type="entry name" value="ADIPOR/PROGESTIN RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03006">
        <property type="entry name" value="HlyIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="190"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="229"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="255"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="284"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="316"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="356"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="14"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="210"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="354"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="358"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR604254-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0020834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="425" mass="47861" checksum="666EB22B63584A64" modified="2023-09-13" version="1">MAPTLRQRPNRAPSSSSTTTTTTSSIPLVAPSLISSSKTATHSHSLTPDAFIEVESDLLHDMQDTLEESISKTNETVAATWRSTKASANETIRVVENQMSETWDASKAAFEGAKRLLRFEELPEEWQSNPYILTGYRFLSSKRQCLWSIFKIHNETCNIWTHMLGLVGLIGLGLYIHTTFLKHGSFWDHAVFFFFFLAASKCLICSTLYHTFLCHSRLPVMRCAATLDYIGIGVLITASVMATLHYGFFCDVERWIFLAFSFGMGVVGCVLPLYPFFDLPSFRYFRIFIFLGMACSGVIPLSYVAYMKGVVNTWNYIAPFFKSGLAYLFGLLFYGHRFPEKQFPGVFDRWGHSHQVWHVAVVAGIYYHYMAMVHFYNSRFSFGCQSVYGGYEHEHLFTGGQGIQDQLMGGASASWFPTASASASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T309</accession>
    <name>A0A9P6T309_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_003420</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000190">
        <property type="protein sequence ID" value="KAG0020888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T309"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0020888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="341" mass="39083" checksum="19D83280A965C02C" modified="2023-09-13" version="1">MSPSLKNLVQHLLASKDIQRYRKWVNYLWIGTLPPGQYAFHYPNLRTLFLRQVEGRSVNKPELCPQQLIRFNATTLTSLELHGQNEYYTSKFWNAVGELPNLKSLYLEGSTIRKDQSSDFWRACLNLESLRLSSTSISLVDDFGSLNLTFPKLYRLSIIFVGGQIGWEQLELIKRCPRLEELRWKLGEWYSSAELQGAFTRLAIGKAWPRLKRLGLSDGCIRVKDEVLADILDALPRVTMLEVGFTRFGVLGFQVLRRHFGIISILDVTECPAFSRAMFKEVLYSCPCLEEFSGGGILVRDIAESGPWVCLRLQRLHIQFAADPMDTNLNEKVFEKLSRLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T320</accession>
    <name>A0A9P6T320_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_002361</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000158">
        <property type="protein sequence ID" value="KAG0021444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T320"/>
    <dbReference type="OrthoDB" id="2436092at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0021444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="124" mass="14228" checksum="91736420AB8A6699" modified="2023-09-13" version="1">MSSLTLAAGPPPPPADDIMVVTEPNYDNYTVGETLYAKAFLRSEEFKELNPKVTITIQKSIRYPKLNQRLGSIRAQLLEGPGFAFKLKEEWLIEEQKNVPFRIRVSWSSPKSGYQDSEDFYFHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3K4</accession>
    <name>A0A9P6T3K4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">UTP--glucose-1-phosphate uridylyltransferase</fullName>
            <ecNumber evidence="3 7">2.7.7.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">UGP1</name>
        <name evidence="10" type="ORF">BGZ80_011535</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Plays a central role as a glucosyl donor in cellular metabolic pathways.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>alpha-D-glucose 1-phosphate + UTP + H(+) = UDP-alpha-D-glucose + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:19889"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="2.7.7.9"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the UDPGP type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.9" evidence="3 7"/>
    <dbReference type="EMBL" id="JAAAID010000094">
        <property type="protein sequence ID" value="KAG0022654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3K4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003983">
        <property type="term" value="F:UTP:glucose-1-phosphate uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006011">
        <property type="term" value="P:UDP-alpha-D-glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00897">
        <property type="entry name" value="UGPase_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.160.10.10:FF:000001">
        <property type="entry name" value="UTP--glucose-1-phosphate uridylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000002">
        <property type="entry name" value="UTP--glucose-1-phosphate uridylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002618">
        <property type="entry name" value="UDPGP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016267">
        <property type="entry name" value="UDPGP_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43511">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01704">
        <property type="entry name" value="UDPGP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000806">
        <property type="entry name" value="UDPGP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 10" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="9">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>UTP</name>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>UTP</name>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>UTP</name>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>UTP</name>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="390"/>
        </location>
        <ligand>
            <name>UTP</name>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000806-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000806-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0022654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="502" mass="55814" checksum="F35E90CDFC4C89AE" modified="2023-09-13" version="1">MSSTLNTPNPSHHPHTLSTLDFQGASSAAAANAMRTELNRLISQVKDEKERLLFQNEMGNFFLLFNRWLADRSKGTKINWDKVNSPPEDQVVPYDSIPKVESSAHLNKLAVLKLNGGLGTTMGCVGPKSAIEVRDGMTFLDLSVRQIEYLNKAKNVNVPFILMNSFNTDEETKRIVQKYATHNIEILTFNQSRYPRINKDSLLPTPRHPNGDIADWYPPGHGDLFDSLNNSGLLDQLIADGKEYVFVSNVDNLGATVDEGILNHMVESGAEFLMEVTDKTRADIKGGTLIDYEGQIRLLEIAQVPSEHVEDFKSIKKFKIFNTNNLWVNLKAIKRVVEDRELSLEVIVNNKTTDSGEKVIQLETAVGAGIKHFHNAHGVNVPRSRFLPVKSTSDLFLVTSDLYSLTHGELSVNPKRMFNTVPLVKLGDHFKKVNNFLSRFNNPPHILELDHLTVTGDVSFGSDVVLKGTVIIVANAGSHIDIPSGSILENKVVSGNLHILDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3R2</accession>
    <name>A0A9P6T3R2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Chromatin structure remodeling complex protein sfh1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">SFH1_1</name>
        <name evidence="8" type="ORF">BGZ80_000267</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000105">
        <property type="protein sequence ID" value="KAG0022428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3R2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000228">
        <property type="term" value="C:nuclear chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006939">
        <property type="entry name" value="SNF5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10019">
        <property type="entry name" value="SNF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04855">
        <property type="entry name" value="SNF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="GATA-type" evidence="7">
        <location>
            <begin position="459"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="155"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="519"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="83"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="521"/>
            <end position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0022428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="553" mass="62615" checksum="E89B6F693E43EC7D" modified="2023-09-13" version="1">MHLQQHQMQQQQQRPPLPQQQQQFQFQPQKGFPMQQQPHLQQLPMQMQMQQPHPQPQQQQQYTQFRPPAVAAAQPRYPMNGGTPLQQHSYHQQHQRPGGPGSAASGALGAMPHVQGTYSTYASRIRDASNALVLPPALGRKAKRAAVASMMESDEDDWDFEEGGSSRSTPNKVQRQLEKERLEREKKAWVRRARKTRHVHNSQQALEASAEQDAILVPIRLDIDTDEIRLRDTFTWNVNEQLMTPEQFAEILCDDLDLNFNKFVPEIAQSIRNQIAEFEPIAEAQVPTEGARTVIQLDMHVGGINLRDRFEWDVGSDLTPEEFSKQMAADLGIGGEFVSMIAHEIHEQLFRFKQDRILDRGFEPEPLFTGFRPVDDAENWCPALETLTAEEYEKILEANDRSVRRNRRETSRYGNRRRGGFGAGSGSIFSYGGGGRSFYNTGNNRRGRPSKSATMNMEPYEGWQCQQCGLGAFSTVMLRSGPAGEKTLCNTCGLHWMVHDSLPEDRKGLFMFKMEEKSIEATPTSNNTATIENADAEPSTEPKVEPVEPTTAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MD46</accession>
    <name>A0A9P6MD46_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AMME syndrome candidate protein 1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AMMECR1</name>
        <name evidence="2" type="ORF">BGZ80_008369</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004507">
        <property type="protein sequence ID" value="KAF9992892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MD46"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.150">
        <property type="entry name" value="Hypothetical protein ph0010, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023473">
        <property type="entry name" value="AMMECR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036071">
        <property type="entry name" value="AMMECR1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002733">
        <property type="entry name" value="AMMECR1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13016:SF0">
        <property type="entry name" value="AMME SYNDROME CANDIDATE GENE 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13016">
        <property type="entry name" value="AMMECR1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01871">
        <property type="entry name" value="AMMECR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143447">
        <property type="entry name" value="AMMECR1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51112">
        <property type="entry name" value="AMMECR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMMECR1" evidence="1">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9992892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="98" mass="11432" checksum="D5D028CFFA371781" modified="2023-09-13" version="1" fragment="single">VSLLTDFEVAENYLDWEVGVHGIWIEFRDTNNRKRTATYLPEVAKEQGWTKEKAIESLLRKGGYKGTITQEVLDSIILTRYQSQKAQATYQEYLDSRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MD91</accession>
    <name>A0A9P6MD91_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Crinkler effector protein N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_008312</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Host cell</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004465">
        <property type="protein sequence ID" value="KAF9993012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MD91"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043657">
        <property type="term" value="C:host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045379">
        <property type="entry name" value="Crinkler_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20147">
        <property type="entry name" value="Crinkler"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Crinkler effector protein N-terminal" evidence="4">
        <location>
            <begin position="19"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF20147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9993012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="80" mass="8899" checksum="4C70681D0AF37858" modified="2023-09-13" version="1" fragment="single">MANQPPSLETEDSAKGVELEFFCILERESTAFPVKIFSSQNIGNLKKAIKAEKKPDLDNIAADKLTLWKAEIPIPDIDEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MDQ9</accession>
    <name>A0A9P6MDQ9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ubiquitin-conjugating enzyme E2 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">UBC8</name>
        <name evidence="2" type="ORF">BGZ80_008043</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004247">
        <property type="protein sequence ID" value="KAF9993748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MDQ9"/>
    <dbReference type="OrthoDB" id="269518at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24068">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBC core" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9993748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="52" mass="6137" checksum="4157382E2F18410B" modified="2023-09-13" version="1" fragment="single">MQEFYVRFHGPADTPFANGVWKVHVELPDQYPYKSPSIGFMNRIFHPNIDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MDV4</accession>
    <name>A0A9P6MDV4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">AMP-dependent synthetase/ligase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_007837</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the NRP synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004094">
        <property type="protein sequence ID" value="KAF9994340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MDV4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043041">
        <property type="term" value="P:amino acid activation for nonribosomal peptide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12117">
        <property type="entry name" value="A_NRPS_Srf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12780:FF:000012">
        <property type="entry name" value="Non-ribosomal peptide synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.980:FF:000001">
        <property type="entry name" value="Non-ribosomal peptide synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.38.10:FF:000001">
        <property type="entry name" value="Non-ribosomal peptide synthetase PvdI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.980">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.38.10">
        <property type="entry name" value="Luciferase, Domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF1">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="4">
        <location>
            <begin position="19"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00029454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9994340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="442" mass="48849" checksum="8459B382902691D7" modified="2023-09-13" version="1" fragment="single">SWNATDAVYPDDICIHQLFENQVKKSPDTIAVVYEDQSLTYRELNARANRRAIQLRDRGIEPGCFVVTMLERSFELVITQIATLKVGAAYVPIDPKAPVDRQSFVINDCGARLLVIGEKTKIPVEFEPMSMRLSNDCTDGNDSMEHVADLNLAGSTRDTAYAMYTSGSTGTPKGVLVPHKGIARLTINNGYADIGPNDCVAFAANPAFDASTFEIWAPLLNGGRVAIIDSDSFTDSRRLSEAIDRYNITAMFLTTVLFNQFVSSIGSSLAKLKYLISGGEQESIESYKKLLGYGGPQHLVHCYGPTETTTFATTYEVTRIEEHQTRLPIGRPISNTKTYVLDTLRRPVPMGVVGELYIGGPGVANGYLNRPDLTEERFLPDPFCGHADARMYRTGDLVRYMPNGDLLFVGRNDHQVKIRGFRIELGEIEARLSELSIVKEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ME42</accession>
    <name>A0A9P6ME42_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNA binding protein, heterogenous nuclear RNP-K like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">HEK2_4</name>
        <name evidence="5" type="ORF">BGZ80_007689</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003988">
        <property type="protein sequence ID" value="KAF9994793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ME42"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd22456">
        <property type="entry name" value="KH-I_Rnc1_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22457">
        <property type="entry name" value="KH-I_Rnc1_rpt3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049786">
        <property type="entry name" value="Rnc1_KH-I_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10288">
        <property type="entry name" value="KH DOMAIN CONTAINING RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="140"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="89"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="89"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9994793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="230" mass="24817" checksum="A871D3A9BEABE1AB" modified="2023-09-13" version="1" fragment="single">TSSVRLLISHNLMGTIIGRQGLKIKYIQDASSARMVASKEMLPQSTERVVEVQGSIDAIRIAIYEIGKCLVDDWERGVGTVLYNPSAPITGNSSGAASGSRPKYTSRTGNGSDFTRTRTEAFGGGGGSGGYPNNNVNNANLRTQEISIPADMVGCIIGKAGSKISEIRRLSGSRISIAKTPHDETGERLFTIVGTMESNEKALYLLYGQLELEKERRLNMAGDQVEEDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MF02</accession>
    <name>A0A9P6MF02_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">DUF914-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_007203</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC35F solute transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003648">
        <property type="protein sequence ID" value="KAF9996612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MF02"/>
    <dbReference type="OrthoDB" id="429955at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009262">
        <property type="entry name" value="SLC35_F1/F2/F6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052221">
        <property type="entry name" value="SLC35F_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14233">
        <property type="entry name" value="DUF914-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14233:SF4">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER F2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06027">
        <property type="entry name" value="SLC35F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="120"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="143"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="175"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="239"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="270"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="301"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="328"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="12"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="23"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9996612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="378" mass="42965" checksum="519D290BA74E0A4C" modified="2023-09-13" version="1">MSSEHQIYSDAPDSKLEHEQQRQFESQVSPQETGPATFRERYASLFSKKFLLILAMGQLLSLCITATTIFSTELTQGDNPVSIPTTQSFLNYLVLAIVYTSITIYKKGFFGWINIMRRRALYYIIFALIDVEGNYFVVKAYNYTSLLSVMLLDAWTIPCVVLLSVFFLKMRFVRWHYLGVFLAMVGLGLLIWSDMVAGENYPGTDYVKGDILCIIGASLYAFSNVGQEYLVRQMPMYEVVGQLGFWGTIINGIQLAILERNELKNITWTGSVIGYIIGFDIAMFILYSVSPLLFRLSSATFFNLSLLTSDFYGLLFGLFLFQSKINKIYPIAYVVIIVGIIVYNIYPAPEPKFKSRLVEDPIVEELEQVEAKDNSTMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MF68</accession>
    <name>A0A9P6MF68_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NmrA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_007117</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NmrA-type oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003590">
        <property type="protein sequence ID" value="KAF9996964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MF68"/>
    <dbReference type="OrthoDB" id="3358371at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05251">
        <property type="entry name" value="NmrA_like_SDR_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051164">
        <property type="entry name" value="NmrA-like_oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748">
        <property type="entry name" value="NITROGEN METABOLITE REPRESSION PROTEIN NMRA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748:SF11">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="3">
        <location>
            <begin position="2"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9996964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="310" mass="34054" checksum="A47D5B6B69C971F2" modified="2023-09-13" version="1">MSKVLVVFGATGQQGGAVANYVINDPVLSKEFKVRGVTRDASKPAAQALKQKGIEVVEGNMDNIESLKKAVQGAHTVFAITSSIHDENLKKREIAQGKAMADAAVSQGAQYIIFSTLPHAGRMSSNKYTKVDHFDGKAEVEDYIRTLPIKSAFFLPGFFMQNFKSIVAPQPNGDGTYTLSNVVSPKTELPLIDIIHDAGKYVGAILADPEKYEGKVLTSATKVYTFEEIVKIMSEATGKTVNYKQIPESVYRGFLPPSAAEELIQMFLLYQDFGFNGPKTRELVEQTAQIARGKLTTFEEFVVNEPFQLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MFE1</accession>
    <name>A0A9P6MFE1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Mitochondrial inner membrane protein oxa1l</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">OXA1L</name>
        <name evidence="12" type="ORF">BGZ80_007309</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the OXA1/ALB3/YidC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003716">
        <property type="protein sequence ID" value="KAF9996226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MFE1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032977">
        <property type="term" value="F:membrane insertase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032979">
        <property type="term" value="P:protein insertion into mitochondrial inner membrane from matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20069">
        <property type="entry name" value="5TM_Oxa1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001708">
        <property type="entry name" value="YidC/ALB3/OXA1/COX18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028055">
        <property type="entry name" value="YidC/Oxa/ALB_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03592">
        <property type="entry name" value="yidC_oxa1_cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12428:SF66">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE PROTEIN OXA1L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12428">
        <property type="entry name" value="OXA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02096">
        <property type="entry name" value="60KD_IMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="3 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="195"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="Membrane insertase YidC/Oxa/ALB C-terminal" evidence="11">
        <location>
            <begin position="35"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAF9996226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="298" mass="33033" checksum="8D2920EFB6B7EBD0" modified="2023-09-13" version="1">MQYGDLKAMGLVHFTPVGGLETILEAVHISTGLPWWATIAATTVMIRTALVPFIVKLQGNTARLHNVKPQLDRLTENMKLAKESNDSAALARFSAETQELFAKNDCNPLKSLMLPLMQAPVMISFYLALRDMAHLPVPQFKEGGIAWFTDLTVADPIYVLPVASSLGFLAIMELGSEAGGVSQPKGVKNIMRFMAVAMVPLTMHFPSAIFVYWLTSNVFTAGQIMFFRVPAVRRFFNIPQLISHPKPKAVGKQPGFMESFRASYEGGIAAKEKEIALAKERESKLAAQKLRRQNRKRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MFL2</accession>
    <name>A0A9P6MFL2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ferritin</fullName>
            <ecNumber evidence="6">1.16.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_006941</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>4 Fe(2+) + O2 + 4 H(+) = 4 Fe(3+) + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:11148"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="1.16.3.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the ferritin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.16.3.1" evidence="6"/>
    <dbReference type="EMBL" id="JAAAID010003470">
        <property type="protein sequence ID" value="KAF9997711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MFL2"/>
    <dbReference type="OrthoDB" id="186462at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004322">
        <property type="term" value="F:ferroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006826">
        <property type="term" value="P:iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01056">
        <property type="entry name" value="Euk_Ferritin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1260.10:FF:000002">
        <property type="entry name" value="Ferritin, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001519">
        <property type="entry name" value="Ferritin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009040">
        <property type="entry name" value="Ferritin-like_diiron"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008331">
        <property type="entry name" value="Ferritin_DPS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11431">
        <property type="entry name" value="FERRITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11431:SF75">
        <property type="entry name" value="FERRITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00210">
        <property type="entry name" value="Ferritin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="Ferritin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50905">
        <property type="entry name" value="FERRITIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="2 6" id="KW-0409">Iron storage</keyword>
    <keyword evidence="3 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ferritin-like diiron" evidence="7">
        <location>
            <begin position="7"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR601519-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9997711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="172" mass="19061" checksum="ECE73336A0396859" modified="2023-09-13" version="1">MSALAKQNFASASEDSINNQISQELQASQVYLSLSAWAGSGQALPGLEKFFKKSAEEEREHAQKLIDYQNRRGGKVVLQTLSAPEIDWSSARNAIEATLQLEKDVNKSLLNLHKVSEENSDAQLSDFIASVYLPEQVEGIKKIADLVAQLNRVGNDGLGLYLWDQELLRSLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MFN3</accession>
    <name>A0A9P6MFN3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Translation elongation factor EF-1 alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">TEF1_1</name>
        <name evidence="10" type="ORF">BGZ80_007081</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003566">
        <property type="protein sequence ID" value="KAF9997101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MFN3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03693">
        <property type="entry name" value="EF1_alpha_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03705">
        <property type="entry name" value="EF1_alpha_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000003">
        <property type="entry name" value="Elongation factor 1-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000005">
        <property type="entry name" value="Elongation factor 1-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054696">
        <property type="entry name" value="GTP-eEF1A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44830">
        <property type="entry name" value="ELONGATION FACTOR 1 ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44830:SF1">
        <property type="entry name" value="TR-TYPE G DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22594">
        <property type="entry name" value="GTP-eEF1A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 10" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Translation elongation factor EFTu-like" evidence="8">
        <location>
            <begin position="104"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="GTP-eEF1A C-terminal" evidence="9">
        <location>
            <begin position="183"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF22594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9997101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="306" mass="33333" checksum="DF826EA3BC28324F" modified="2023-09-13" version="1">MDTTKWSQDRFEEIVKEVSTFVKKVGYNPKAVAFVPISGWHGDNMLEESTNMPWFKGWTKETKAGSQKGKTLLEAIDAIEPPSRPTEKPLRLPLQDVYKIGGIGTVPVGRVETGIIKAGMVVTFAPSNVTTEVKSVEMHHEVLTEGIPGDNVGFNVKNVSVKDIRRGNVCSDSKNDPAKEAASFNAQVIVLNHPGQISNGYAPVLDCHTAHIACKFAEILEKIDRRTGKAMEEFPKFIKSGDAAIVKFIPSKPLCVESFQEYPPLGRFAVRDMRQTVAVGVIKAVEKTDGKGGKVTKAAVKAGGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MFR9</accession>
    <name>A0A9P6MFR9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_006894</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003430">
        <property type="protein sequence ID" value="KAF9997981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MFR9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="118"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="179"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="53"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="118"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="134"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="196"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9997981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="361" mass="42037" checksum="C09AD1E751D22DB4" modified="2023-09-13" version="1">MQEQRHELKNTWQGERLKDEQRVQQIKQQHHQAQLERQVCLKQLQLEHEQRLAQELQARGLAMKERKEVLQRELNEERLKEERNLDIMKEGQQKQRLEREQRLHALWEGYEREFKQEHNQRQLAIRNRERTAEATRSFSNARSSTQELHDIQLKEQYLQQLKKNQLEQQLKEEEHLKQLDKGHKQQRTEQSNQQKGVREQLLREKELPAKEHSETLVVKERRQVPPQQLLHQDHTPSSKSQQAVKSIFRRRRNSVSEADRDEAAVSAVPAVPVVPVIPGADACAAAHHHQSLMSSGSGATINSNKATYTPSHAEELSGAAGPEDQIMWVKTAVETHNYNGNNGQEIANMVESHQDLVNPDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MHA6</accession>
    <name>A0A9P6MHA6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006239</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003070">
        <property type="protein sequence ID" value="KAG0001108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MHA6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0001108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="114" mass="12614" checksum="9A0886594EE71133" modified="2023-09-13" version="1">MDNSLTATEASLAMHPSVDGPASWTTSQGEDAEGVMGMHGDDGDMQDSDDPDTTDNFDQELDESQDQEDEDDLEAKMDELYHQLQTETKAKESAESLLEARVGYENFDNDFDAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MHR3</accession>
    <name>A0A9P6MHR3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ubiquitin carboxyl-terminal hydrolase 35</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">USP35</name>
        <name evidence="2" type="ORF">BGZ80_006133</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003012">
        <property type="protein sequence ID" value="KAG0001717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MHR3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="USP" evidence="1">
        <location>
            <begin position="120"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0001717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="298" mass="33236" checksum="8C3A49CA7BE165A3" modified="2023-09-13" version="1" fragment="single">SALTEEDKQNITQDMKTLQKFAEKCCISANPPLEHAVQEDNAFATEVCNLAQILVIHFGDSDDVGTKVQKARTFLDLPVVTRPEALRTMNEFSWKKSLHIQNTSAGFRRKPAFTQPLGKVGLVNLGNSCFMNSALRALFCSTDFKQAILNDTSKVDSSKIMTTRLRETFSGLATPRLSIIKPSTLYKALPDWLNDGHQQDAAEFTKILFSRLEDEDPISKKALASFHGVVVNQIKCNACGTVSSNKEDFYDLTIPLPRSESADLQSIVDIFPSTEELNEENNNKYFCDNCKSLQAAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MIN2</accession>
    <name>A0A9P6MIN2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005967</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002940">
        <property type="protein sequence ID" value="KAG0002507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MIN2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="269"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="512"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="279"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="512"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="526"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="863"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0002507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="863" mass="96229" checksum="015D8A20998956D5" modified="2023-09-13" version="1" fragment="single">IASGELYEEKFGQPEAHPTLNIGNILPPTFILLEGFETDLNVAPILPLLQAHLESFEDNQRLKKDDIALLMSHYHLQHLNSTFLGVNRERRSAAEGTTNTSTTKHPLWDKAADLIRQSSNTKDIPINPSGVSCTITEHIGEFATATTNLWDGSIYKKSLDYLLRILLRVNLAPVRESKNKERTKAETQKRHDRSEKTIKMTLGLWRSKVWGLCDQLDKALHSSNPTAKSKNRILAITKRLSTLQREKLEVSHTRLPSLKAQLSQLGGSIASAGSGEPSLFDDEDDMDDDDDDDGDDGNLGDVDWVRKNDFSDRECEEVARIAIILRPYVPKRQKSSGKSGTKEAVAHVALRAPIVLIANKILRATGYHDFARKISPQVPATSIHSLHLGSVGFYEVLCSSRPERFDVMDADGNPLTYVKNVTLHQRNKEAVLGAFLDLEKVKKICNSYGLTFGNSKFDQRKKTRADGENKWVKEYIERGLTKSEVQTQAETCSTVVKQKEAQVKKLRKAVSNKQALQTSASQSHRKAQDKASKSDAYAKLRAARETLRDGRKALSLKKRLSETSAKSNKISSSAEKAAVSDEDYAVQVETRVTVPTWIHPASEDKAEFFDISELVANARGKNRLITFAGTDYGLHRMSETVAMTQSQIESHINRYHALFGYEGEASSEYLSAPVGIGIDLPSISPSPLPESLSDLKLPKSNKITAAQVNSLSRSRKVSKKRERRLKKDEKVVEVFGVVSDKINSLTTADSMTAIDLAHDARKKVRDTLREFEASNPRQKELHTQRIRTKRTWSAMCANERRYVQQYAVQEHARNQKPIQSSSQAVELATGISRGSISDSRLMTQGLNLVDKQVILSDVSPIDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MIS0</accession>
    <name>A0A9P6MIS0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_005923</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002919">
        <property type="protein sequence ID" value="KAG0002719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MIS0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="73"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="268"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="331"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0002719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="411" mass="43944" checksum="71B1120165DA9DBB" modified="2023-09-13" version="1">MATLATTTTQSTSTSQSTMAPTSSSSSASSTSLSSAAAVSPSTSLTSPAPTRRPDTGDNQLFGRPSVIGEYNLTLGILICSGITLVFLITVAIATFKRAQLRKQFRIDEEKTGRVAAIGKGGKGGKGGKGSDAKNADVKDAKPEVKEKDTSREAVTLPSRQATIRRALLEDARRENEARARTPENKLGGQDSPIDRNGSFKRQQQPQPQPRSDRARIEMNTRFQDREVNYDDVYQDDYSLPPLTASSTDDAYYSGGFSNAIQAYHYDSPQIPNPAYQQQQPTRPLQPVKRTGSGRSSNGNAPALSTKSVNRVPSLRNERPRPKVSTQGFDNSGSSSSSRSNSSSGSNVSSPVDRIGQRFGRGGGSPVAQIEMDSYPSPVARSNSSRLPFEMRGASSGHGQAQNGRSVGAYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MJ21</accession>
    <name>A0A9P6MJ21_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_005820</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002868">
        <property type="protein sequence ID" value="KAG0003262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MJ21"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035591">
        <property type="term" value="F:signaling adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052574">
        <property type="entry name" value="CDIRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47566">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47566:SF1">
        <property type="entry name" value="PROTEIN NUD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="150"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="337"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="363"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="419"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="535"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="605"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="9"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="22"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="91"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="150"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="172"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="193"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="256"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="270"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="377"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="426"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="605"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="616"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="665"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="873"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0003262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="873" mass="97165" checksum="6CE5482CF95B423A" modified="2023-09-13" version="1" fragment="single">MLRAPVPTYTPSVRQSTPGRRSSPSASLSSAESSPASSLSTKEQRQQQLQALQRQQQLQYKIQRRQQRQLQELEEQQQYLSTDRCDKDRQQAVSGQPTWASQEIKDTWINVADEIGDKDISAQWERHHSRLSDKHMDTSATKLLEDETPPKIMDGWHLDDLDDDHRSPTPPTATTTTTATNTRFNEQNDRNIAKNNNDNTASNENNIKTKTAHGYVHMGTERATKGTVRPRSRDEAQDLKNGNSNVHGDHEHVRKNSSTPHKGSNGSKYPWRDSKHETIFTDLTDEQSNKTQLRDHGALATTPRPQPIVRKSSQQDDQISEADSYLSLGDIIDAVNNGDGSMDPARSSKFKQAKQRLAELSLSQQDMQDDQDGLSSPLTDSTASRTFQNNQEAFRQQRLRVISAASRIDLNDNRSFALSGEKRDAANTNTNPTGSRDTEIGDRGSTTSRDSVYRDSLSGSTLGSAGFQAQLEGIKKHELATVLTVLNSATVAQLFPESEENASRILPYNVNAKSPIPNTKQEDVSVTRQLPGAAATPDVILSEDADATPRPRTRIYNSSSRRINPENDIARAKQYANLASRGLSKQASSFVEELANATAMKSATDISFKNNTPSPESRKSERQAVSDHIPSTINERRESAEVDADQQEQLKREVAFRGVSSLQQQEDKNVGVDDAERSDTEVDDLGLLAGSRAMEIAFKSLQDLDVSIDLNSIRRAQTDDEDGDGYLSEVMLPSKPKRRGEYSLKWENQLDADTSSRHGFNTSFSRSRSFSNPASGGMVAEQSSFSHAEEKLVHFITALNPWDEWDQVKSLDLTKRQVESTIKLNNLVPNLEVLILNDNQVPYLTGVPKSVKTLQVRSNLLDDLTNFSHLSNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MJ57</accession>
    <name>A0A9P6MJ57_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_005800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002855">
        <property type="protein sequence ID" value="KAG0003394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MJ57"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0003394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="287" mass="33338" checksum="E2832DDA07127BA5" modified="2023-09-13" version="1">MRKIYFTFKYDIRFAFEPRRLSDKHLNILACFPNLVNLRLSFMNSKFNLNGFEKVAGVWTQLQELTAPGCEISDENLALVISNMNRVKRLVVPGADFGPLALAALRPHFPHLKELNMSLSAINMGAATVEILASCSQLQSLTADRVAGWRVREGEEWACQQSLKSLEVCFVLSRPNPKYRQQQLIFERISELRNLERLDISNRKIPDRDLRYTLDFRLGRGLGVLKTLKALREFHFEYTKQWMETEEVEWMLENWPQLEVVMGPLNVDNDIDARLKSLFCDNYIDAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MJC5</accession>
    <name>A0A9P6MJC5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_005588</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002750">
        <property type="protein sequence ID" value="KAG0004631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MJC5"/>
    <dbReference type="OrthoDB" id="10335669at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0004631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="129" mass="15299" checksum="82275E979CAA8621" modified="2023-09-13" version="1">MHFLRVVLPRRHRSAGAQQLRTHRGQYRDRPYDEMRKSMDLLYTTEVVPFLEKRAEAQALEAMKRIKTKICKVAVEEAKKARVTCHFQDSISDLEDSIEKGLKENWRKDILAFYDLSDDDFAELQELRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MK56</accession>
    <name>A0A9P6MK56_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Reticulon-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_005313</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Endoplasmic reticulum membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002623">
        <property type="protein sequence ID" value="KAG0006407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MK56"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003388">
        <property type="entry name" value="Reticulon"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02453">
        <property type="entry name" value="Reticulon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50845">
        <property type="entry name" value="RETICULON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="Reticulon" evidence="7">
        <location>
            <begin position="1"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0006407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="142" mass="16280" checksum="099845D386725EA3" modified="2023-09-13" version="1" fragment="single">KYYSRSAEFLHLDADRLHRRVDYVTDGLNVVLTELAKVVLIEDNKRSLKFIGIFYVIWTLRTWFSTTTLLSLILVSLFAAPRLYLDNQALIDAHVAKTNDLVQAHVGKGRQVAQEHFNSVYSKAEQFAKDKGLLKKADKKVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MK95</accession>
    <name>A0A9P6MK95_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_005271</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002605">
        <property type="protein sequence ID" value="KAG0006487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MK95"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0006487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="379" mass="41969" checksum="77B5B3C265678DF7" modified="2023-09-13" version="1">MSCTANLLSNDTSKYFEKEFIAKASNVCKDGTFDHDDEIVNLLAKLKGSIDNGGPSMVRDDATIMRAEMVRKRREQGQSTRSRTEKILEAVETACDLVSEKPFGKAPSECDCLNAWVNIFKLLLPDGLTCHTGETSLGSSKPVQSELASEYGNELSESGRRVDLRFSYKGIEVANIELKSPTEKRTSRAKQTRKSIRLSRCIQRSLEKKGLESPTIMSADIAGYMALFYSVAKVEDIYVSSMISNHSVCLPTSKHTLSKFLDGKSLSCMSNFVKYLAELGEMAFDAAEEQQADFAINEFVDDIKYTAPTEQCVSKSFEATIILSPKRKRASPGDPSSLNLRTPKWTQSNLVWDGEVETGAETENGFTSFQNMIAMSPKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MLF1</accession>
    <name>A0A9P6MLF1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">GTP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">SEC4</name>
        <name evidence="6" type="ORF">BGZ80_005146</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Endomembrane system</location>
            <topology evidence="5">Lipid-anchor</topology>
            <orientation evidence="5">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002555">
        <property type="protein sequence ID" value="KAG0006772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MLF1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01867">
        <property type="entry name" value="Rab8_Rab10_Rab13_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001728">
        <property type="entry name" value="Ras related protein1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001447">
        <property type="entry name" value="Ras-related protein Rab-1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050305">
        <property type="entry name" value="Small_GTPase_Rab"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47980">
        <property type="entry name" value="LD44762P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00046278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0006772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="240" mass="27196" checksum="34B251A42F7B7028" modified="2023-09-13" version="1">MSTPKSASYDYLIKLFLIGDSGVGKSCLLLRFSDDSFTPSFITTIGIDFKIRTIELDGKRIKLQIWDTAGQERFRTITTAYYRGAMGILLVYDVTDERSFSSKYKDRIAQVIRIILYWSYVWDKTCINMQCHTNLDIRNWFSNIEQHASEGVNKILIGNKCDMPDKKVISKDQGQALADEFGIKFLETSAKSNICVEEAFFSLARDIKKRMIDTQTNQTQSPNTLVVDDKGGKAGNGCCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MLS1</accession>
    <name>A0A9P6MLS1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_005055</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002510">
        <property type="protein sequence ID" value="KAG0007054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MLS1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00083">
        <property type="entry name" value="bHLH_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47787">
        <property type="entry name" value="CENTROMERE-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47787:SF1">
        <property type="entry name" value="CENTROMERE-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BHLH" evidence="2">
        <location>
            <begin position="292"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="444"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="21"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="97"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="131"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="183"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="253"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="445"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="459"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0007054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="471" mass="50680" checksum="EDA1931DD0362BB1" modified="2023-09-13" version="1">MSPEDPKLQSPGDSGSMVEHSNASSGRTSSKSSTGSQQLPTFGDLSKPSTTSGFSSSSSSSSSRSLHTLYPNSTPPMSPGHVLISPVSRPHCGITDPSQYSSSSSSSFYQLPPPLQPFAPRQSPHQSPAIQPQSSQGHSLPSLPPLPSSAHPNGYSPRTTPQIPNNDPLILKQSIPAMILPDSALSSSPSSHETTSRSYSTVMPHRDTEMSSPTSAPVADQSAPSSPRRFVMLPPQSIPTTTTSHRSSRSQTRKASVGSSTGSSSTSAPTSPPARRRTSSVKLIDQETRDLMRKVSHSAIERRRRERINDKILQLKHLVPACVDEDHLHKLSILQSTIEYIQHLKSILPPSVANAKVGKATNNNPKNKTTDMLEAMGGSISAKSPLTPLMTTGLNHIYSKRIKVEKQEIRALLKDHAMSMSSSSSDEDAKDGLLLLAGQSSVAFVDDDDDDEQEDSRRSPRRKVPGSRKHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMA0</accession>
    <name>A0A9P6MMA0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Oligopeptide transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_004904</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002454">
        <property type="protein sequence ID" value="KAG0007241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMA0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035673">
        <property type="term" value="F:oligopeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004648">
        <property type="entry name" value="Oligpept_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00727">
        <property type="entry name" value="ISP4_OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22601">
        <property type="entry name" value="ISP4 LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="88"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="195"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="221"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="297"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="352"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="377"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="417"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="459"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="527"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="577"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="608"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0007241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="671" mass="75572" checksum="11AC9427176B8623" modified="2023-09-13" version="1" fragment="single">FFYLRQANIVISYSVVALLSLPMGHFMAATLPTRQFKIFGAKCSLNPGPFSIKEHILIGTMVACNSGTAYAVDIVILQKLYYGSEKPFIAGMLLVVTTQVFGFAVAGAVRCFLVRPAHMIWPQTLVVASLFRSLHSTQVQDNSNRMSRMKYFLLVSGGMFLYYWLPGFIFPTIGVLSWMCWIAPDNIVLAQLTGSYGLGIGTIALDWAAINSFVYPLITPWFAQVNILVGFVMLTYVIAPWAYYSNLWGSKNFPIVVPYLYTEDGNEYNISMVMKDGGNGLDVAAYRAYGPIRMDSFFALSYGVGFAALSATVVHVLLYNGKDIFERWRYSRVESEDIHTRLMSVYPEVPDWWYGLLFVSMFALSMFTCVMWDFMPWWALILALAIALLFVLPVGIVQAVTNQQPGLNIVTEYVIGYLLPGHAIANVTFKTYGFLINIQAISFITDLKLGHYMKIPPRVMFMVQLISAVISCIINLVVAIWLIDTRPNVCTEEGYPYTCRSTITFYSASIIWGAIGPARTFGSTDGAIYGPVQWGFLIGAILPLVFWLASRKFPHVEWLKYVHWPVLLAATSNLPPGFPYMYSNGLFVGFIFAFLLRRYRYNWWARYNYLTSAALDTGVAVSALVIFFAFQAWEIQFPYWWGNPDPSNPDLNAASLDHCYQGGSNFYGEQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMI5</accession>
    <name>A0A9P6MMI5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004850</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002429">
        <property type="protein sequence ID" value="KAG0007286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMI5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0007286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="99" mass="11391" checksum="58D1A6913CCB93ED" modified="2023-09-13" version="1">MLSRIFKDGAPEDTIHVIVEQPKDNSNREPEKAICPEYPDREGGEAVITVEHCKGTPQHEDGRVERPSDDAYFRNIIQQYRKTNTKTITDFTLTEMNNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMM3</accession>
    <name>A0A9P6MMM3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Threonine/serine exporter-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_004092</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ThrE exporter (TC 2.A.79) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002127">
        <property type="protein sequence ID" value="KAG0007902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMM3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010619">
        <property type="entry name" value="ThrE-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051361">
        <property type="entry name" value="ThrE/Ser_Exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31082">
        <property type="entry name" value="PHEROMONE-REGULATED MEMBRANE PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31082:SF4">
        <property type="entry name" value="PHEROMONE-REGULATED MEMBRANE PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06738">
        <property type="entry name" value="ThrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="Threonine/serine exporter-like N-terminal" evidence="3">
        <location>
            <begin position="6"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00034125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0007902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="96" mass="10424" checksum="6FFB0839FF72007B" modified="2023-09-13" version="1" fragment="single">MFGVGASILVAFVAKALRDYVCFTGVVLSAIVMLLLPGLSLTTAIMELSSRFIISGSVRMFYSLMYCLFLGFGISIKSNPWDAINEPPPGDMKMGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MN03</accession>
    <name>A0A9P6MN03_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">40S ribosomal protein S4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">RPS4_2</name>
        <name evidence="2" type="ORF">BGZ80_004036</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002102">
        <property type="protein sequence ID" value="KAG0007961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MN03"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06087">
        <property type="entry name" value="KOW_RPS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.30:FF:000005">
        <property type="entry name" value="40S ribosomal protein S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000876">
        <property type="entry name" value="Ribosomal_eS4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032277">
        <property type="entry name" value="Ribosomal_eS4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041982">
        <property type="entry name" value="Ribosomal_eS4_KOW"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11581">
        <property type="entry name" value="30S/40S RIBOSOMAL PROTEIN S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11581:SF0">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN ES4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16121">
        <property type="entry name" value="40S_S4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="KOW" evidence="1">
        <location>
            <begin position="19"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0007961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="105" mass="11673" checksum="69DB9DF6CC95FBD7" modified="2023-09-13" version="1" fragment="single">VNDTIKLDLESGKFTEFVKFEVGNVAMVTGGRNTGRVGVITHKERHVGGFDIVHIKDVLDRQFATRLSNVFVIGEGNKPWVSLPKNKGVKLTIAEERDRRRAAAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MN93</accession>
    <name>A0A9P6MN93_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001970">
        <property type="protein sequence ID" value="KAG0008285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MN93"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0008285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="187" mass="20537" checksum="08E46FE00E026819" modified="2023-09-13" version="1">MAQPPGLPEKNGMAKTATSRTEGLSFSQGNQPDQPYAALNSSQLSLLDVEDAIESIVSKNTSLQTKALYELTEDMAEAADDDVVVLGRRKVEEEEESRNTSSTSNRDGVSARVLKRTRLTSNEKADMLDAGCKMIRKSRLKTMAQFMLIRSMLVMNDQTASALNANKIPRSISSLKSPCRSSPRRSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MN97</accession>
    <name>A0A9P6MN97_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003773</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002012">
        <property type="protein sequence ID" value="KAG0008176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MN97"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="276"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="136"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="167"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="306"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0008176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="322" mass="36181" checksum="348561751D3B7220" modified="2023-09-13" version="1">MDEVPSLIMKEGNNQGSDNLQNVTKYARHMLLRNDITEQELKSVNVALSRIISSTMLEGEKFFGPIIQEFKSKISLHEYSLPVLDVEGQEQLVLQSRVKNGLREELAEERQPSEPWIASSSATVEEITAISTPIILTPQTSTLQPTSTATRSNPSFEGKNEDKSAKPKSQSQSQSISLHNSSLKEPSVNENDDIDPPNMMDDDDNIRHELPNSFYSGDYELANCEFKLPGASDIDSVELPRTKSGLKIFLGGETLELLFTFVDHLRQMLEGLQEEAEEKKELDVRRKHQHNFTSSNSPPQKERRISNNGFLSPTSPGKKLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNC9</accession>
    <name>A0A9P6MNC9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">mRNA export factor GLE1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Nucleoporin GLE1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BGZ80_003296</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GLE1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001865">
        <property type="protein sequence ID" value="KAG0008565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNC9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044614">
        <property type="term" value="C:nuclear pore cytoplasmic filaments"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000822">
        <property type="term" value="F:inositol hexakisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031369">
        <property type="term" value="F:translation initiation factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016973">
        <property type="term" value="P:poly(A)+ mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.510">
        <property type="entry name" value="GLE1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012476">
        <property type="entry name" value="GLE1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038506">
        <property type="entry name" value="GLE1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12960">
        <property type="entry name" value="GLE-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12960:SF0">
        <property type="entry name" value="MRNA EXPORT FACTOR GLE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07817">
        <property type="entry name" value="GLE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="7" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0811">Translocation</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="97"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="277"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="118"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="277"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="297"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00026227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0008565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="548" mass="61552" checksum="093CBA486C6A48EA" modified="2023-09-13" version="1">MATNELPLELILRRSITDGPINPDDLELTKLRLSQKQGLSSPLDEEEEQDYILHHNNHIPLSKNPSIYYQKIGLTSTQRTKPTKSIYLNTFNSRASRSRSGEDAVSHRSGYGLSEFSSSEEEVSSEDDNYSYDTSDSEEEAFPLSSRRYANPGRVLPDADGRSQEMAHYVAHITGRIDPWELKRVAPHIAQKIADDFKSLETLAKKPTVSWDNGDIAQRLKAMTLDTEAIKEKRKKETEAKNQALTKEIENCLARIKEERETAIRLREEAIKQAQQEKERLAKEQEDKAKALAAQKEAQEKKASEEAAAKAEKAKKAAEAAAQKASAGASAIFVSEAANAEYQRYIKVLEHIRSVVLPAVTGNPQLKKFCFGARREIVASIGQLVNRRSEILRVATEIDGFFNTTKSQNESAYNWVLNCTAKKLVKQAETEALVKSAPTFPLAHVAVLLFTNHPLFLDVLMARFAKKCPYVTPMYIQKDPNDTAEEYMEKLAYKKTGKGHETEAQYNARQCAMFTLYCAILQTNPPGKLFSLWSSTGSHFIFYVAAVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNH7</accession>
    <name>A0A9P6MNH7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_004061</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002114">
        <property type="protein sequence ID" value="KAG0007928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNH7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0007928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="67" mass="7478" checksum="897DB191117C909B" modified="2023-09-13" version="1">MADVNGNVAKIYKIICMNDIHACGEVTDLPVYIPSNEGELLEFICDGGRQLAILWNFVVNVQRVEKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNT8</accession>
    <name>A0A9P6MNT8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Golgi apparatus membrane protein TVP38</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Golgi apparatus membrane protein tvp38</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BGZ80_003233</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Golgi membrane protein involved in vesicular trafficking and spindle migration.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TVP38/TMEM64 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001847">
        <property type="protein sequence ID" value="KAG0008626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNT8"/>
    <dbReference type="OrthoDB" id="166803at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000022">
        <property type="term" value="P:mitotic spindle elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051076">
        <property type="entry name" value="Golgi_membrane_TVP38/TMEM64"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032816">
        <property type="entry name" value="VTT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47549:SF1">
        <property type="entry name" value="GOLGI APPARATUS MEMBRANE PROTEIN TVP38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47549">
        <property type="entry name" value="GOLGI APPARATUS MEMBRANE PROTEIN TVP38-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09335">
        <property type="entry name" value="VTT_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="148"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="177"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="315"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="domain" description="VTT" evidence="12">
        <location>
            <begin position="168"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="70"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="352"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="397"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="501"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="18"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="70"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="92"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="357"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="454"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="466"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="525"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF09335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0008626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="560" mass="60824" checksum="E9088924ED7FABBE" modified="2023-09-13" version="1">MNPYDTDNFEEEPPPLFSTNSATNSSSSPYTPTTKNNNTNNSNNNSLRLDRQGSTNSVAAATSLNTSIFGSASPLTPTPRSGQFSRDGFTPLNGSKDSTSEENPNSRIFLGLWIAFVALMIGLFTGFHSKIFALLEALAGSIKGLGPWGPPVIMLCLFATSFPPVIGYSSVITMAGYVYGFLFGFTIVFLAALSGAIVCFYFCRRWFKPQVRELLAKDKSLKSVVRTVERSGFRLLVLIRLAPYPFNIMNALLSATHISIQTFALATALSLSKLTVHVYVGSTLSSLTGENGDGNDDGTGEPGNPSNGHGKALKIVVMVLGVFLGFGVGAYVWMVTKREIAIAEADRLERRRRRRREQSLRRELNSDRSTTGAGNAIELSDHIPGVDLTGRELSFDRMARGRQTSGSSEHVGGYREGYRDEEEDVHEGQSLFGRLGLGRNSQNQRGDEWRNAGANVNSLSGTDNSDFSDDDDGDDEEEEAEVGEYGADLNVLERGSNFRGEIGQDDGEGALDFSAHHMGLVESPWQDDEEAEGGDSADLLNTNREEGGRPGGGDLWDRGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNU3</accession>
    <name>A0A9P6MNU3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">60S ribosomal protein L38</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPL38</name>
        <name evidence="5" type="ORF">BGZ80_004045</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL38 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002108">
        <property type="protein sequence ID" value="KAG0007944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNU3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022618">
        <property type="term" value="P:protein-RNA complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.720.90:FF:000001">
        <property type="entry name" value="60S ribosomal protein L38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.720.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002675">
        <property type="entry name" value="Ribosomal_eL38"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038464">
        <property type="entry name" value="Ribosomal_eL38_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10965">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10965:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01781">
        <property type="entry name" value="Ribosomal_L38e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0007944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="102" mass="11467" checksum="F0413304104A43B0" modified="2023-09-13" version="1">MTALIVDAPKTKGGLIHKPYRTLSNSALLLSQPKQIQDIKQFLEIARRKDAKSGRIKKNGSQTKFKVRCSRYLYTLVINDAAKAEKLKQSLPPTLSIETIKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQ38</accession>
    <name>A0A9P6MQ38_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Folliculin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BGZ80_002476</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell projection</location>
            <location evidence="2">Cilium</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
            <location evidence="4">Cytoskeleton</location>
            <location evidence="4">Microtubule organizing center</location>
            <location evidence="4">Centrosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
            <location evidence="3">Cytoskeleton</location>
            <location evidence="3">Spindle</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
            <location evidence="5">Cytosol</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Lysosome membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the folliculin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001612">
        <property type="protein sequence ID" value="KAG0009356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQ38"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005819">
        <property type="term" value="C:spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904263">
        <property type="term" value="P:positive regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037521">
        <property type="entry name" value="FLCN/SMCR8_DENN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021713">
        <property type="entry name" value="Folliculin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037520">
        <property type="entry name" value="Folliculin/SMCR8_longin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032035">
        <property type="entry name" value="Folliculin_DENN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31441:SF2">
        <property type="entry name" value="FOLLICULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31441">
        <property type="entry name" value="FOLLICULIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11704">
        <property type="entry name" value="Folliculin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16692">
        <property type="entry name" value="Folliculin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51834">
        <property type="entry name" value="DENN_FLCN_SMCR8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0966">Cell projection</keyword>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="13" id="KW-0458">Lysosome</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDENN FLCN/SMCR8-type" evidence="17">
        <location>
            <begin position="149"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="22"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="278"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="510"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="28"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="58"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="84"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00004656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00009987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00021824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAG0009356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="705" mass="77352" checksum="D01D3ECC12EA5400" modified="2023-09-13" version="1">MNALIALAVWCQPHGPVTILTTQHRRPTSSPSSTSSTSSLPNGISLAKDSTPAPDCNNDLSNTPVSTALSANDTLPLTPAQPPLDTTQGAPDTSASTSNPPHSLEPKKSRRSLQPSPGGTCHSPVGSRPSSAHPALSPSTNNSSCECQFSIPSGEKSLHSVDPLNSEISYISQPVPVDASLFAPIRIACIRSLNAETYCGREGSVFFGDGVNGYVLSYMFTVYDAQSRGHRVKYTIMTMMTDRVYLVANMEYLISQFQVIASNLQSMANALCPPQQSPATRSLSYSSSHHRGSIMPENAPTKRGRPLTDVLAKPDIFVQLHAAFVSVLSNCSRRLTERHIQGRLVVEQKQETQSSESGKQQPAINSLRDLRQVLGKQQFNRLVWNTVVGNQVIVRGDNSSIVNEIIRLLEDILPKDCCTVITEGSAYEPSYACNILGLDRSVPIPTDLDPQDFILLDICTNTLSYQDITPPGSLQADNHKKDGSVAEPPIYQADWSTATLVADMKELSTRTEKDGLENGDPPYIQTGQLRPPASSPGAVDSTGATFQNQKYLLQAGEEPPELLQPNSRNVNELDTVGRKIPSPQNQQCSLYVETINEILDYKFPRTLESKRLSLLREEWIRQVKNFYMTVFKSIQFHNLYKAGKASDEGVVDGFLQSMRVDKRDLKILRFFTRCAKSSSFQSQKYRSEDPVVSGTHTIIHGIPAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQ83</accession>
    <name>A0A9P6MQ83_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_002355</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001578">
        <property type="protein sequence ID" value="KAG0009473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQ83"/>
    <dbReference type="OrthoDB" id="5399166at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031083">
        <property type="term" value="C:BLOC-1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0099078">
        <property type="term" value="C:BORC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032418">
        <property type="term" value="P:lysosome localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017246">
        <property type="entry name" value="Snapin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31305">
        <property type="entry name" value="SNARE-ASSOCIATED PROTEIN SNAPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31305:SF2">
        <property type="entry name" value="SNARE-ASSOCIATED PROTEIN SNAPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="75"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0009473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="237" mass="26523" checksum="4AE3091A6EE8D9AD" modified="2023-09-13" version="1">MSFFRKDYSAYPQPVVVTPDPRYAGGSISEAVAEAIDTEHTSKYRNNTVDNHQTESIRAPRSSGGTGDDAEQDNSSEQQLPPRQLQQENTQHESSSQVTTTQELQQKDSAKLADGIMSLLGPIVQEMDFNIVSVRKSQSELEKEIERLMAGMYRELPIYELLSTELLVDGSLTFLFTFDASAVELQLFMASSAAPPDVEPAVQKLLKARRQIMTANSTLKTVQDRVDRMHLQIARRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQN6</accession>
    <name>A0A9P6MQN6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">WD40 repeat-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_002269</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001555">
        <property type="protein sequence ID" value="KAG0009559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQN6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848:SF8">
        <property type="entry name" value="F-BOX AND WD REPEAT DOMAIN CONTAINING 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="37"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="79"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="121"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="163"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0009559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="190" mass="20578" checksum="98495F4B6CE06206" modified="2023-09-13" version="1" fragment="single">MVICSAYSPDGKTYAAGLYNGSINLYETSSWNRMQRLKGRSEGVSSLSFSATGGQIASGSGDKTVRMWDVDAGECVHASHGHSSTVWSIVYSPKGDRIASGSEDKTVQLWDIDSGECIHILQGHYGAVQSVVYSPKGDRVASGSVDKTVVLWNVETGKRAHTLQGHRYWVRSVVYSPNGDRIASESKDKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQV2</accession>
    <name>A0A9P6MQV2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">MIR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_001547</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001356">
        <property type="protein sequence ID" value="KAG0010363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQV2"/>
    <dbReference type="OrthoDB" id="5588846at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036300">
        <property type="entry name" value="MIR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016093">
        <property type="entry name" value="MIR_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46809:SF2">
        <property type="entry name" value="GH21273P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46809">
        <property type="entry name" value="STROMAL CELL-DERIVED FACTOR 2-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02815">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00472">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82109">
        <property type="entry name" value="MIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50919">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="MIR" evidence="3">
        <location>
            <begin position="128"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="3">
        <location>
            <begin position="193"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="3">
        <location>
            <begin position="253"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0010363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="304" mass="35835" checksum="A29760A675A922F2" modified="2023-09-13" version="1">MPTPQITQKFRSPIDGRIVAIRAWDDVGYKFVLWKHILQSFGDDVRVLRAGDVDIHCMLNKKFEDLLPLRIQYVPDTILDVILNEEPSLSVKDKNEEPPLSVKEKNEEEKKLSIEKSVLPAYSSAPNDDYIRFGSRIYLRHVDTCGFLRTPNLHYRVDLGQSDQYIVYNFHSLEPDREDWWEVTAPKDEKDHVYKLPYGSRLRLFHVDKRRWLHSHYYKSPVTPNQQEVTGFGNAETSDANDVWIVERVEGCSEFWRTSDVFILRHEATNRYLHSHPVRCYGEKEVVAFDKRNDINNLWRAQFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSG1</accession>
    <name>A0A9P6MSG1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Epsin-3, clathrin recruitment and traffic between the Golgi and endosome</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ENT3</name>
        <name evidence="3" type="ORF">BGZ80_000766</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001168">
        <property type="protein sequence ID" value="KAG0011330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSG1"/>
    <dbReference type="OrthoDB" id="4033880at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030125">
        <property type="term" value="C:clathrin vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030276">
        <property type="term" value="F:clathrin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006895">
        <property type="term" value="P:Golgi to endosome transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16992">
        <property type="entry name" value="ENTH_Ent3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.90:FF:000006">
        <property type="entry name" value="Clathrin interactor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013809">
        <property type="entry name" value="ENTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12276:SF45">
        <property type="entry name" value="CLATHRIN INTERACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12276">
        <property type="entry name" value="EPSIN/ENT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01417">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00273">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50942">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ENTH" evidence="2">
        <location>
            <begin position="25"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="291"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="363"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="388"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="475"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="388"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="407"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="479"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0011330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="500" mass="53308" checksum="5F02B13E87C97232" modified="2023-09-13" version="1">MENFIENVSGYSMWDIRNAIEKVTAKVMNYTEMEQKVREATSNDPWGASGTLKQELAQATHNFQYFNEIMPAIFKRFTEKEPREWRQIYKSLVLLEYLVTHGSERVVDEARSHISTIKILRNFQYIDDNGKDEGINVRNRAKEFAEMLSSVDRIKEERKRAKANRNKYVGSEGSGGGFAGTGSKYGGFGSDSYFDGGSGGYGGSGSGSGSGSSFRDQASSRSGRYDDEDRDPSTSPPARRNPRIKNEAAKASPKPEPVKEVNLFDFDEPAVSAPVGQNAFVSNVSKPADDGWDAFQSATDDFDDFQSAPPVEQNASAPAPLFSTYNPAVANVLPPVRTNSTSSNANNGFGNFGAKSTTGGGIDLLGSSPIKTSPMPPFGNSAIPPLASSSVAPNSSSKSASSFAAPINNSKPASNPNDIWASASGLISLDGLGKAKPKEAAPSMNALAANSWNSGAWASKPAAPAASSQAPMAFGNLGSMATSNNQPAKKNNYNFDDLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSG6</accession>
    <name>A0A9P6MSG6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Leucine rich repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_000579</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001120">
        <property type="protein sequence ID" value="KAG0011587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSG6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15454">
        <property type="entry name" value="NISCHARIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15454:SF69">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE 11-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52075">
        <property type="entry name" value="Outer arm dynein light chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="22"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="420"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="686"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="910"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1014"/>
            <end position="1038"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="32"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="43"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="431"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="708"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="744"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="772"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="810"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="840"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="857"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="917"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="936"/>
            <end position="945"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="972"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1022"/>
            <end position="1038"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0011587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1038" mass="112995" checksum="2AC7DCA0F6C35BED" modified="2023-09-13" version="1">MDQPIDGDKYVRTLSHYFRHNHKRLVPIDPPSTTNDNNTNNGNGNGNGSGSGSGRSTKSTSPMSHGVRSFITPADPMAAAYSGMVNSLWSVGSAVVDVVATTAHLGSDKHGAATTATEGQVLKPGVSSAAQDRDSFHGAWDGTGTILSDSSPRERQLYLQAQLKAPIFPMDLYYLLYLLDRFELEGINIDGWDGSTPRAVGDSKPRVLNNGTGLPDPSTYSSFPPPTATRPQSIRSFSSTALSTLTLITGWKQWSTAASSSSNNAMTIADDVHFIHKFLKKITGLRLVSKIPPGFDVPVKGRIEGYSGEGISSLLRVLQPDQDSIIFRQSPPPQLLLPLGATFSSLTHLELHKIPPRSIDGWECLMPQLKSLVVIQSGIEDVHDVIVTAVVESERRRRERVSKEKNRAVLIRQEQREALKDAAMTSRSRRMGQGSTSSTSSLSPESSQASSPSSLSQSGGTMFGSDFANDDDLAILNSIKMWPVLRHLSVSDNALAALQNDDTFSYTQAIVTLDLSNNLLVSPPPCLIHLHNLHNLNLSYNLMTNVQAIYQILGNVTELNLRGNRLESLCGLERLWNLEKVDVRENNLVEAAEIGRLAALPGIREVWSEMNPFCTIQPKYRLEILAVFKANGHDLLLDGTFASFIEKRTLANMSPASFSSTISSIVNLANIPAASVPSAVLAKELASPPPRITRPDTATTGSGAGSSERGDSTDRRSSSTRSRDDSLIATPPPGSRPSSQPQKLVKKKLVKSSKRVKRIVNLDSDHEHDEDGNSIEEEDGDEQSHDHHHHHHHDEDAAYSKVLGPPVTIGKKKVIKKKPATTESGVGATATEGGAEEKKTKKKVVKKKKNQGPVSFANNNDENNNGNTANNNNNNNNTAAGNGDDDETSCLDKRCKDNRHVHRLALLEESMNGVKLHNNTNSNSNHNHSARHPHHDSHSHNNDHGHNHHNHNHHDNDSNSHGSIHHHHHGDANSLRAPSPLLDYSSSDDGGAEGYRRKIEAIRNEAGPNWLKVWAEMGGGSETQQPQEAQRNSSSFGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSI1</accession>
    <name>A0A9P6MSI1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_000835</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001184">
        <property type="protein sequence ID" value="KAG0011230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSI1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050562">
        <property type="entry name" value="FAD_mOase_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356:SF2">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356">
        <property type="entry name" value="FAD-DEPENDENT MONOOXYGENASE ASQG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0011230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="293" mass="33702" checksum="519ED4AD39866980" modified="2023-09-13" version="1" fragment="single">MKDQSERTGYEYLICSRSNLYELLLTQLNAANVVIGKKILWYEENELGVNLCCSDNSIYSGDILIGADGVHSRVRHTLHKVLAKKNMLSKSDSQPIKPSYVLVAGVTHRQSAERYQCLKDPFVHFCSVVGVQGRGWNVINIPDDQICWAMWVQLDSAKYAQIEDTEDVELGVENTEPIVEWFRDMPCPYGGTMGNLVNSTSEDLKSKMYIEEKLFNTWYHGRVVLLGDACHSSWRDRFSRYAVFNWAPQSYFQRMLEEGITYRPQASFLAHAENRGMAPVVPQRPWKQWSEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTM5</accession>
    <name>A0A9P6MTM5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">MTHFR SAM-binding regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_011154</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the methylenetetrahydrofolate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000863">
        <property type="protein sequence ID" value="KAG0013321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTM5"/>
    <dbReference type="OrthoDB" id="16284at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004489">
        <property type="term" value="F:methylenetetrahydrofolate reductase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00537">
        <property type="entry name" value="MTHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.220:FF:000002">
        <property type="entry name" value="Methylenetetrahydrofolate reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029041">
        <property type="entry name" value="FAD-linked_oxidoreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004621">
        <property type="entry name" value="Fadh2_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003171">
        <property type="entry name" value="Mehydrof_redctse-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053806">
        <property type="entry name" value="MTHFR_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00677">
        <property type="entry name" value="fadh2_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45754">
        <property type="entry name" value="METHYLENETETRAHYDROFOLATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45754:SF3">
        <property type="entry name" value="METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02219">
        <property type="entry name" value="MTHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21895">
        <property type="entry name" value="MTHFR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51730">
        <property type="entry name" value="FAD-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0521">NADP</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MTHFR SAM-binding regulatory" evidence="9">
        <location>
            <begin position="300"/>
            <end position="580"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF21895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0013321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="623" mass="69845" checksum="1323E394E169162B" modified="2023-09-13" version="1">MKIIDRIKKGQEEGRPLFSFEYFSPKTAQGMVNLHDRIERMCYLGPEFIDITWGAGGSRPAATIEVVSNAQKVYGVETCMHLICTNNPTDKIDKALKEARACGNQNILALRGDPPHGQSEWSACEGGLNYASDLVRYIRQTHGDYFGIGVAGYPEKHPESPSMEQDLLYLKEKCDAGADFIVTQLFFDVPLFLDWVKKCRAIGITCPIIPGVMPIQAYASFKKNIVGLSVPQWILDGIEPIKNDDQAVRAFGVEVGIKMTKELLAGGVCGIHYYTFNLERSTRLILEGAGLVNKMDYIKKNMPWRSSFDEKRKEESVRPIFWSNRAKSYISRTDNWDEFPNGRWGDSRSPAYGDLDRYGVYLKYTSDEAIQNWGSPNSVDDICQLFVKYCNGETLTLPWSDQALALESGTIKDRLVELNSLGYLTINSQPPVNGAKSDDKVFGWGPKGGYVYQKAYLEFFVSPETLEKLKQRIGKFPGFTYMAINKAGDLHTNTNANKPNAVTWGVFPGREVVQPTIVELSSFDAWKDEAFALWEQWSKCYPQGTSSREVLAELGQTWYLINIVNNDYHEKEGVFELFKEDLLVLQASKAAAMEAISEQIKEIGINGAEIQAESAAITPVVTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-02-05" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTT0</accession>
    <name>A0A9P6MTT0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_011169</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000867">
        <property type="protein sequence ID" value="KAG0013297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013694">
        <property type="entry name" value="VIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45737">
        <property type="entry name" value="VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45737:SF6">
        <property type="entry name" value="VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08487">
        <property type="entry name" value="VIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13768">
        <property type="entry name" value="VWA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SMART" id="SM00609">
        <property type="entry name" value="VIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51468">
        <property type="entry name" value="VIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VIT" evidence="3">
        <location>
            <begin position="644"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="2">
        <location>
            <begin position="919"/>
            <end position="1098"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1324"/>
            <end position="1370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1420"/>
            <end position="1510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1355"/>
            <end position="1368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1426"/>
            <end position="1447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1453"/>
            <end position="1465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1467"/>
            <end position="1510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0013297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1652" mass="183359" checksum="897D7DC00DDCD14D" modified="2023-09-13" version="1">MPETGLEERPQAFRAVHTDQSGICSSVSNTLSIMPRFDGKTGEAVILWNDILMTFKKASYIKNDYDLKPLRIKSTPDVILDVVIEPSDSDTATNSFRSMDSPSLTIRASVTPTARNFQSPPPMEPYVIGSVSPPTTLTKCNQISRDRSATPHLDEALHGNDLSSPEHTVAALRFTSADGVVMDNFAAPVESTIPSVEMREGDEHMPIDVKEDYDQGLMYFEGKGVPQDYVKAREYFVLAARQGHQDAQNKLGFIYNYGKGVPQDFYIAAGWYFKAASQGYAKSQCNLGFLYDSGQGVKQDYTKAIEWYMRAARQGNSKAQCHLGLMFENGKGVPKDYYLAFDWYQKSARQGNSKAQCNLGFLYESGNGVAQDSSKALEWYRKAADQGNAKAQCNLGLMYENGIGVAKNYTKAMEWHTKSAMQGYAKSQCHVAILYESGHGAPLDYSKALEWYMKSAEQGFAMAQCNVGYMYEIGKGVTKDYGKALEYYLKAAARGFPTAQTNIGIIYYNGYGVAQDYAMAMEWYLKAAYQGDPIAQCILGLMYENGTGVPRDFDQAFEWYHRAAKKGNAIAQCNLGGMYENEKSPKRDNSKALEWYLKAANQGLARAQFNVGAMYESGRGVQTDLEAALEWWEKAASQGDEEAQRMIDQINGSRRQYLPLVDIEVHTTILETISRTKLTQTFFNPPENGDIQELQYTFPLYDGVSVVRFACHIGDRTIIGLVEEREKAKKKFKDAVSRGEKAALLEQLPSSSDVFITTIGNISSGAEVIIEISYIGELMHDAQVDGIRFTIPTTILPRYGEHPVEIAQGTVSEGHIQITVDVVMAATSVIQQIQSPSHPIAVSIGTTSIAPAAAPVMSKASATLSLGSAELDKDFVIQVVAKDMGVPTAILETHPIIPNQRAVMTTLVPRFSLPPGKPEIVFICDRSGSMEGDSITLAKSALRVFMKSLPVGIKFNICSFGDSHSFMWDKSQSYTQENLNAAIRYVDAIQANMGGTEMYNPIKATIERRYKDIPLEIMLLTDGAVWNHQKIFNYLNGQVIENKAAIRVFTLGVGRGVSHALIRGVAKSGNGFAQTIGQGEKMEGKVVRMLKGALSPHVVDYTLELKYSRENRVDEANDDDEEFVMVERVADSLNVKLELVDDLEDKFEPPQQEQKPTSLYDATVDLDKEKSDPSIDINEERYLRLPSLTPPKLLQTPHIIPPLYTFDRTNIYLLMGPECNQMTPSSIVLRGTSKHGPLELEIPIQVLDTPGETIHQLAAKKAISELEQGRGWITQAKDEDGLLNKSKFESQFTEMTEREAVRLGVQFQVQGKWTSFVAIKVQPADDTPTQDRAGDTTSQTPARDYKEATAPTLYTEDNQQQPTVTSNLSRREELEVKRMRLAELRCSRESRRASLATREPTTGRVIDDLVLSLIAAKPYTPKTSDECDYESNSDENDCEESDSDDSDMGIRRNTASRSRLSANIFSSDDDDDDDDDDDDDDDDDDGDGSGNDDGDDDGDDDDDDDDDDDDSEAFTAMRKCKKKKKVSCFFGMEAEVDDEVDEGAVATMPRLNGSKLEILIDLQTFQGSWDWAQMLFDCIAVAATDAEKVAKDDGWDENVVATALAILFFEKKLVEEKDTWELVVDKARGWLEEQIGKDGAVAVFQEATKLFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MU35</accession>
    <name>A0A9P6MU35_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PAS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_010964</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000823">
        <property type="protein sequence ID" value="KAG0013614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MU35"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAS" evidence="1">
        <location>
            <begin position="19"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0013614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="386" mass="43453" checksum="A50CAF7F2332EE07" modified="2023-09-13" version="1">MFQPYSYIAFHDTTPRATFLWLSPAISYILGYEPEELIGTSPYDIILREDIDMTQSAHKEVAMDDLVAGQVSFRFIAKNGSYVPISLLMNVCYDIGITCGTLLNANDYVQFAAPSTAMGYNLGSRKKEFERIKRHHKAFQADSNLWNAHGFETEPRVCMILNRFTRNLIVMYASSACEIIFNIKPEQIEGKPILLFVRADELGSFVEQVDVSKSSGAIMQIRFWFQSPNMSHEIPCEAVLFGSTDGIVAVMRRCKPFVRRHLIGNGSANSEYYSPASSHTTQNASWSSCSTASSSLPSSFSMSRSLTQAKLKSIKIVDRNDGNIRPLEEVLPVHASEIDIDTQRLGIRDISKQDYVDDYDDDDNDDDDYNGVGDGTVYIQERMREL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MU56</accession>
    <name>A0A9P6MU56_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_011699</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000974">
        <property type="protein sequence ID" value="KAG0012498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MU56"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="149"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="292"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0012498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="327" mass="36847" checksum="AFFCDBF66E1ABBEB" modified="2023-09-13" version="1">MAKDHPYWEKALQVFWAISTYGCVFSLMGIIWFIATWVMYELQGNDRPFNILQHKALQGNGTPTPMIRYAATHLYQAYRPNANDPLSSKIKAFIGYGGQTESYSYESSVDHIPFTNGTYDNTTTIIVIRPSTNIESIMYAVDETTFRDTLAKIGGLIGIIASVIIFLFGHTRLSPWGILARFPPFRTKIINGIEGRCKKNEEDKMSEDDEKSEENENNENEKDGVNEKDGESEKNGENEKNEKNEKNVRPGAIFTKRYSTTDSANELGQLHKRLDELEVVLEDYYLDGKFFRESFKKSGRGESSTGRGPSTGGGRAEENSNTQQPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MU73</accession>
    <name>A0A9P6MU73_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_011607</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000954">
        <property type="protein sequence ID" value="KAG0012647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MU73"/>
    <dbReference type="OrthoDB" id="2432222at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0012647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="465" mass="52693" checksum="EA470E3AB35A65E9" modified="2023-09-13" version="1">MATALELPDITRLLGELLDKKTLKSCVLVSRSFYASYAPFLWRKVTLNGPEKLMDLAILKAQADHVQELNINNSIPSEYYDIKFKRLKAVRLSMDNSSFFSDRPADDAIDNVYPDYTPFARLNPTINTLLFFDMQLPSSSAFWDAVATDWDDPKVTTLTLDFVDRNKPDIFRPLDQLTLVKACPHLTTLGWKAVADEASSLAFKQEFDNASWPELTSVSLSGSVFDDEIIASIIKAAPSLKKLDNPSGMFGPEAHASIIQSQYNKLEWLSVKNCSSFTSAMAQEILSRCLLLKHFEAPSIHLKDIARSGLPWVCLELEKLTIQFEKQPEDPIEWERDVFGRLSRLTRLKHFDMGFGYRGFHRNGSPVVSKQSIDLSLASGLGSLASLKEIQTFHFEGTVQEMGKDEIQWMLDHWKKLTKSRGRFSQDKSQHQELAVLLNERGIECDLEEDEGIVICRFSHDVVMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUC2</accession>
    <name>A0A9P6MUC2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Proteasome subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">PRE3</name>
        <name evidence="11" type="ORF">BGZ80_011510</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Cleavage of peptide bonds with very broad specificity.</text>
            <dbReference type="EC" id="3.4.25.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">Component of the proteasome complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the peptidase T1B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000934">
        <property type="protein sequence ID" value="KAG0012787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUC2"/>
    <dbReference type="OrthoDB" id="7854943at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019774">
        <property type="term" value="C:proteasome core complex, beta-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004298">
        <property type="term" value="F:threonine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03762">
        <property type="entry name" value="proteasome_beta_type_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000010">
        <property type="entry name" value="Proteasome subunit beta type-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000243">
        <property type="entry name" value="Pept_T1A_subB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016050">
        <property type="entry name" value="Proteasome_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194:SF0">
        <property type="entry name" value="ATP-DEPENDENT PROTEASE SUBUNIT HSLV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="METALLOPROTEASE TLDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00141">
        <property type="entry name" value="PROTEASOME"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00854">
        <property type="entry name" value="PROTEASOME_BETA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="6 10 11" id="KW-0647">Proteasome</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0888">Threonine protease</keyword>
    <keyword evidence="7" id="KW-0865">Zymogen</keyword>
    <feature type="active site" description="Nucleophile" evidence="9">
        <location>
            <position position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR600243-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0012787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="211" mass="22669" checksum="31B99789AEE992D0" modified="2023-09-13" version="1">MAGLKAGEVNLGTSIMAVQFDGGVIIGADSRTTTGSYIANRVTDKLTEVHDTIYCCRSGSAADTQAVADIVHYYLQMYTVQNGKPTVPLAASLFQEMCYQNKDNLMAGIIVAGWDKDNGGSVWNIPLGGSLHRQPFAIGGSGSTYIYGYCDANYKDGMNQEQCIEFVKNSLALAMDRDGSSGGVIRLAVITEKGVQRLFIPGDKLPVHWQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUX5</accession>
    <name>A0A9P6MUX5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alpha/beta hydrolase fold-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_010417</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000722">
        <property type="protein sequence ID" value="KAG0014482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUX5"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF8">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="3">
        <location>
            <begin position="234"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="3">
        <location>
            <begin position="432"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0014482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="592" mass="67134" checksum="BAB5D40F0754D7AB" modified="2023-09-13" version="1">MVSAQAANDFATDSISSHTNALSPQIPKPSLLQRAYLKGILHRPRDIIFLVRLIVAAVWAMVRLHCIELPFMIVTFFKYPTKQHALGWPWWLTISMSFIRAIGPQIRTIGHLRFVGLFIEAALPLQVLFARNVKVERNVQFRVRLNALLRPERASLAQIRQELRSCGYSDDVTNPSKEYLDSMHLPAHGPQARLSNIPEEVGHLDKDGTYVLKGEWIEAVYSSNEGRPRNNTVVLYFHGGGHGFLSPASHREFLCRLAKDIGPGARIFSVDYRMGPEHPVPAAIHDAFAAYLYLTEPTHEALILDDKKSCKERVPVDPRDVVVGGDSAGANLAAAFMLYMTKYVQPSTSPKFVLPHATILVSVWADPTSSLPTAHSDDCYCYCPGPIGVHPFNKSDYVNFHITNKMNFASNYICGDFHTSPNPRNSFGLDREWEWYSHLAQHPLVSPVHRANLSELGNTLVHTGTHDRLVDDNRLFAHRLGKENPEKLIRIEVYKDMVHVHHVLSRLKLSRIATRNISRFIERSKHFRDVEEGAVPKDEYRQFDYKDMVKARAADGVEWVMVDQDGMEEAKDEGWPMNVLIKSWPPSYIPEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MV64</accession>
    <name>A0A9P6MV64_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Leucine rich repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_011060</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000842">
        <property type="protein sequence ID" value="KAG0013469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MV64"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd00116">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052410">
        <property type="entry name" value="DRC5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24107:SF2">
        <property type="entry name" value="NLR FAMILY CARD DOMAIN CONTAINING 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24107">
        <property type="entry name" value="YNEIN REGULATORY COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0013469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="822" mass="90901" checksum="810167B60AD12A21" modified="2023-09-13" version="1">MEETQLFRLIGSAVTVEIPVSHVGGQNIVFWEDVEQVFPGMQHVQNGKVAVNVLRDSDGNRTVMLSNYFITVPSITPHRIKHLPGVVLDVIKSTGPSTEESKFREYVVEKVDKLDDNVIKVLHNQRLMQDRLALIQQKAEAILVQNYELLEYTIPRLFIVLPETSMPWDPAKMFRTKFRLYFIYECGEHTKVPGSTFPNHLHLAKHEGYTVNKPTKFFEKYGPFLMAMLHLIKVGAGIAGHLVPALANLKVVDVIDSTLSAVDSVTKQVIDDVDYSIKYLEENRTQIQKSNGVDTEGGEVALRYLESYFSRVEGLEGVDLRQLGSYLKANSPDNLLGNLYCITTDKGHVKWVCIDHYRQAYNERDQQDFEKAVQVNDGSYDPQLGKVVISLGSKIIAEEFFYALTKARRVDDLDITFNWVCSRSDLEKLENALKESRVSILRLDIRKFRTSFGRKLIAASTQYETLFHIVELPNTKRVHVVLPNELAKLSDFKPKRPSDLHKLSCRLDSDSLALRNSLIGDNGAQALSEALKVNSTLTTLSLYNNSVRDNGAQALSEALKTNSTLTTLDLTFNSIGSDGAQALSEALKTNSTLTTLDLTNNSIGSDGAQALSEALKTNSTLTTLDLYDNSIGSSGTQALFEALKTNSTLTTLNLYGNSIRGNTVQRLLKALRTNLTLAILDLTYNSIESNGAQALFEAPKTNSTLTTLIWWNNTIRDDGVQTLSEALKINSTLTTLDLSFNSIGFNGARALSEALKTNSTLTTLNLRDNSIGDSGAQALSETLKTNSTLTTLDLYNNSIGSNGAQALSEALKANSTCRINGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVP0</accession>
    <name>A0A9P6MVP0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_009978</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000649">
        <property type="protein sequence ID" value="KAG0015209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVP0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015112">
        <property type="term" value="F:nitrate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042128">
        <property type="term" value="P:nitrate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17341">
        <property type="entry name" value="MFS_NRT2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044772">
        <property type="entry name" value="NO3_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23515">
        <property type="entry name" value="HIGH-AFFINITY NITRATE TRANSPORTER 2.3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0534">Nitrate assimilation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="102"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="137"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="278"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="314"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="342"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="375"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="409"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="1"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="182"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0015209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="438" mass="46656" checksum="E3FAB9A3C92FE638" modified="2023-09-13" version="1">MPTIKADMNLTASQISNANLTSVGATILARLIVGPMCDRYGPRKVMASLLLIGSIPIGLIGLISDANGLITIRFFIGIVGATFVPCQYWASKMFSPEIVGTANAICGGFGNMGAGVSYFLIPLFYNAIAKSLPLHQAWRVTFVIPACLCIIMAAADYFLGDDCPSGDWKNSGSKPEVFDVEQQGKPQSDLDIDSIHGSQSDDEKSISKGQANDAVIVPVSSPVQQPTGFKALLSQLKNPTVLILMVQYGCSFGLELAVDNVIGDFFHTQFGLSQTTSGMLGSIFGLMNIISRASGGFLADYVNRFIGEGVQGRMLVHICMFLLEGCFLVGFSFAAATLRSSLIVLILFSFFVQAGCGTTFSLVPFVNPRSSGSVYGLVGAGGSAGSIVFNYIFKIYGTNYPGAFRTIGYIAFAAALLTSLIQIQGRMLIGLVFKRMNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MW02</accession>
    <name>A0A9P6MW02_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Chloride channel protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">GEF1</name>
        <name evidence="12" type="ORF">BGZ80_010003</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the chloride channel (TC 2.A.49) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000652">
        <property type="protein sequence ID" value="KAG0015172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MW02"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005769">
        <property type="term" value="C:early endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005247">
        <property type="term" value="F:voltage-gated chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006878">
        <property type="term" value="P:intracellular copper ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04591">
        <property type="entry name" value="CBS_pair_voltage-gated_CLC_euk_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03684">
        <property type="entry name" value="ClC_3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3080.10:FF:000011">
        <property type="entry name" value="Chloride channel protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1280.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3080.10">
        <property type="entry name" value="Clc chloride channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014743">
        <property type="entry name" value="Cl-channel_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001807">
        <property type="entry name" value="ClC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45711:SF9">
        <property type="entry name" value="ANION_PROTON EXCHANGE TRANSPORTER GEF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45711">
        <property type="entry name" value="CHLORIDE CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00654">
        <property type="entry name" value="Voltage_CLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00762">
        <property type="entry name" value="CLCHANNEL"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81340">
        <property type="entry name" value="Clc chloride channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0129">CBS domain</keyword>
    <keyword evidence="7 9" id="KW-0868">Chloride</keyword>
    <keyword evidence="5 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="304"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="373"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="475"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="549"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="590"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="643"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="669"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="716"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="746"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="11">
        <location>
            <begin position="799"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="11">
        <location>
            <begin position="937"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="876"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="993"/>
            <end position="1117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1132"/>
            <end position="1174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1041"/>
            <end position="1050"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1087"/>
            <end position="1108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1132"/>
            <end position="1145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="1151"/>
            <end position="1165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0015172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1174" mass="129897" checksum="CA2DDF483B5F2CF7" modified="2023-09-13" version="1">MQGSLGGAYQSMANQLKQSMEMTQTMSNMMELFLVSSLTISSRIERNDRTDKPLLILTTENKSHFPIPGVSGIIRIGMDNNEERKFESSAGSSATLLSSSMVTIKKGKKESKEKEGTIYVQPHQQMTGGQSQQPSIDVLGPGMRCVDVFELNLERFGEWIILVEASFISPGTGKKLSKKHECCVYLVDQCAIEWLPGNQEKEFESAYTSKMMTGALRQVLKVPMTDGINSFLDRFPAPLHPDLFNEPTGYEKALQEVKQYEDFTTIDWVQDAVRERYRQTTKAAPDGSGSWSSYLYDSYEAGQAWVVVSLVGVVIGLNAALIAICTEWLSDIKLGHCSYAWWLNQKFCCWGFDSEDGYCDDWSSWSSYGIIDYVFYLVFATSFATSAAFLVRRYARYAAGSGISEIKCILAGFIMKGYLGGWTLIIKSLGLCMTVAANLSVGKEGPSIHIACCAGHVVSRLFPKYQRSRAKSREIISASAAAGVAVAFGAPIGGVLFSFEEMSNHFPAKTMWRSFFCALVATVTLQAMNPYRTGKLVMFQVSYDRDWHFFEIIFFILLGIFGGLYGALIIKYNLKVQHVRKRYLADYGVIEAATLAFLTCTFAYWNIFMKIDMAESMGILFRECEGSEDYMGLCKPENTWKMVALLFFALIMRIATCTISYGAKVPAGIFVPSMAIGALFGRMIGLIVRAAQVSYPGFFLFSSCKPDVPCITPGTYAFLGAAAALGGVMRLTVCVVVIMFELTGALNYILPTMITLMVTKTVGDYFGRGGIADRYIRLNGYPFLDKEEHSFGIAVSQVMKKDVTILPASGTRLDRVERLLSDTNYQGFPVVEDSTSRTLIGYIGRSELRYVIDKAKRARNVSPMAHCFFRPGSMESRQHMDQGHVGGVGSLDNDDSSSSRFRHSVEGDVGTSSSGGGGGSGDRGDSETNYVDFGPFIDQTPIAVHPKLPLETVMEFFKKMGPRVILIEHQGKLVGLITIKDLLKYITRTEALDEEEEEMEISGGPFGRRRSDPDTEWASRQWWSSGSSPGGRHSYSRHRQSSSISSIGNGILAGNRNHDRDESPSHSPSGGRDPRGFSASQHHHMKSSTPSAGAGQYTPQTTITQPGRSPSVGGMTLASSIGSFRERFELTENTQPHHGERDVLFDHGGYLDDDDENFDDQDEDEVQLRRHGQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWK6</accession>
    <name>A0A9P6MWK6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Endoplasmic reticulum-Golgi intermediate compartment protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_009951</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ERGIC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000644">
        <property type="protein sequence ID" value="KAG0015255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWK6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030134">
        <property type="term" value="C:COPII-coated ER to Golgi transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045888">
        <property type="entry name" value="Erv"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012936">
        <property type="entry name" value="Erv_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039542">
        <property type="entry name" value="Erv_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10984">
        <property type="entry name" value="ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10984:SF25">
        <property type="entry name" value="ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07970">
        <property type="entry name" value="COPIIcoated_ERV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13850">
        <property type="entry name" value="ERGIC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="domain" description="Endoplasmic reticulum vesicle transporter N-terminal" evidence="8">
        <location>
            <begin position="12"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="Endoplasmic reticulum vesicle transporter C-terminal" evidence="7">
        <location>
            <begin position="146"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0015255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="365" mass="41108" checksum="A1E7FAB939413405" modified="2023-09-13" version="1" fragment="single">MRPMTESNFSRFKNLDAYAKTLDDFRVKTSTGAAVTLASALIIVILFIGELSNYQSIHIESSLVVDSGLNEKMSINFNITFPRVPCDVLTLDVMDVVGAHQPDVLHSIYKIQLARDGTEIKRERTQELGDSGPDLKTFDENYCGSCYGADKPPGGCCNTCDHVREAYERSNWSFNHAENIEQCVREGYLEKLKEQADQGCRLWGELTINKVAGNIHVAPGRSFQRGATHVHDIQQYLSQGLNFSHHIAHLSFGEKTPMTHNPLDDRIVTMKEDGLYMFQYHLKVVGTRYHFLDRIPISTNQYSVTQFNRDLHYKNALGQIQAPNGLPGVFFNFDISPMLVIQKEERKSFVSFLTGVCAIVGGIFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXD1</accession>
    <name>A0A9P6MXD1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein arginine methyltransferase NDUFAF7</fullName>
            <ecNumber evidence="7">2.1.1.320</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_009574</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>L-arginyl-[protein] + 2 S-adenosyl-L-methionine = N(omega),N(omega)'-dimethyl-L-arginyl-[protein] + 2 S-adenosyl-L-homocysteine + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:48108"/>
            <dbReference type="Rhea" id="RHEA-COMP:10532"/>
            <dbReference type="Rhea" id="RHEA-COMP:11992"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29965"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:88221"/>
            <dbReference type="EC" id="2.1.1.320"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the NDUFAF7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.320" evidence="7"/>
    <dbReference type="EMBL" id="JAAAID010000587">
        <property type="protein sequence ID" value="KAG0015866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXD1"/>
    <dbReference type="OrthoDB" id="17415at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035243">
        <property type="term" value="F:protein-arginine omega-N symmetric methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003788">
        <property type="entry name" value="NDUFAF7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038375">
        <property type="entry name" value="NDUFAF7_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12049:SF5">
        <property type="entry name" value="PROTEIN ARGININE METHYLTRANSFERASE NDUFAF7 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12049">
        <property type="entry name" value="PROTEIN ARGININE METHYLTRANSFERASE NDUFAF7, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02636">
        <property type="entry name" value="Methyltransf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5 7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0015866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="518" mass="60346" checksum="D217EF5F794E94D1" modified="2023-09-13" version="1">MSNLPRLSAALAHANVRSRTHYSSRTFRHTITTAASLPRSAVPLVRSSLRNHVHNNSNKPATSMITTKEGFHTSSVRRNLIDDPRFSPEKVAARAKYPIITAKDAAKSNKMPTEVKMLVREFIDDSLYHPHYGYFSKQAVIFSPETDFNFERIKDNMEFLDIIAEKYKEIEDDMDVRDEVARQVWHTPTELFKPWYGYAIAKYIVTEYKLNNYPDKDLIIYEMGAGNGTLMLNILDYIQQFEPSVYERTRYRIIEISKKLAQRQGERQEVRDVTKRHGCVEIINKSIFEWDTLVRDDCFFVGMEVLDNFSHDLIRYDSVTEEPLQGMVAIDEEGDYTEIYTPVQDPLIQKYLAIRKQTGYKPPVLARRFLRRIRNRLPFATNMTGPEFIPTKLLLLLESLKTYFPKHRLVLSDFYTLPEAIPGTDAPVVQTRYSGTMVPCSTYMVMPGMFDIFFPTNFELLKDMYQQVCRPSLGMEKSVKVQTQREFLERYGDLDKTTTYSGENPMLMYYENNKMFLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYH2</accession>
    <name>A0A9P6MYH2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Alpha N-terminal protein methyltransferase 1</fullName>
            <ecNumber evidence="5">2.1.1.244</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">X-Pro-Lys N-terminal protein methyltransferase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BGZ80_006984</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>N-terminal L-alanyl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-methionine = N-terminal N,N,N-trimethyl-L-alanyl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-homocysteine + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:54712"/>
            <dbReference type="Rhea" id="RHEA-COMP:13785"/>
            <dbReference type="Rhea" id="RHEA-COMP:13971"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:138057"/>
            <dbReference type="ChEBI" id="CHEBI:138315"/>
            <dbReference type="EC" id="2.1.1.244"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>N-terminal L-prolyl-L-prolyl-L-lysyl-[protein] + 2 S-adenosyl-L-methionine = N-terminal N,N-dimethyl-L-prolyl-L-prolyl-L-lysyl-[protein] + 2 S-adenosyl-L-homocysteine + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:54736"/>
            <dbReference type="Rhea" id="RHEA-COMP:13787"/>
            <dbReference type="Rhea" id="RHEA-COMP:13974"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:138059"/>
            <dbReference type="ChEBI" id="CHEBI:138318"/>
            <dbReference type="EC" id="2.1.1.244"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>N-terminal L-seryl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-methionine = N-terminal N,N,N-trimethyl-L-seryl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-homocysteine + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:54724"/>
            <dbReference type="Rhea" id="RHEA-COMP:13789"/>
            <dbReference type="Rhea" id="RHEA-COMP:13973"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:138061"/>
            <dbReference type="ChEBI" id="CHEBI:138317"/>
            <dbReference type="EC" id="2.1.1.244"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. NTM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.244" evidence="5"/>
    <dbReference type="EMBL" id="JAAAID010000350">
        <property type="protein sequence ID" value="KAG0018602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYH2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071885">
        <property type="term" value="F:N-terminal protein N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008576">
        <property type="entry name" value="MeTrfase_NTM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12753">
        <property type="entry name" value="AD-003 - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12753:SF0">
        <property type="entry name" value="ALPHA N-TERMINAL PROTEIN METHYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05891">
        <property type="entry name" value="Methyltransf_PK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016958">
        <property type="entry name" value="DUF858_MeTrfase_lik"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="28"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="121"/>
            <end position="122"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00039112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00039449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00043129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR016958-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0018602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="232" mass="25286" checksum="A95F8F9A7A21C2F8" modified="2023-09-13" version="1">MLGGLGQLARPDAVTSLRFLSEFVNPPASSTASSIVSPPPTTANSSGASKRQKLPLPGSGPSHVLDCGAGIGRVTKQVLIKAFDHVDLVENCAAFVKQAKEEYLKEEIELGRVGEVRCSGLQNVNFEGTSWEGRFDVIWCQWVLGHLTEADLIAFFKRCKKGLKPGGMIFVKENNAKVGIVIDEEDSSMTRSDQVWKEMFEKSGLKLLKDDVQKGFPSGLFAVKMYALEPIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZ13</accession>
    <name>A0A9P6MZ13_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Endocytosis defective- protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">END3</name>
        <name evidence="6" type="ORF">BGZ80_006620</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000328">
        <property type="protein sequence ID" value="KAG0018862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZ13"/>
    <dbReference type="OrthoDB" id="1716625at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00052">
        <property type="entry name" value="EH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000261">
        <property type="entry name" value="EH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11216">
        <property type="entry name" value="EH DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12763">
        <property type="entry name" value="EH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00027">
        <property type="entry name" value="EH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50031">
        <property type="entry name" value="EH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EH" evidence="4">
        <location>
            <begin position="7"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="39"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="EH" evidence="4">
        <location>
            <begin position="161"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="404"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="304"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0018862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="425" mass="48048" checksum="B79FB1988B123BD7" modified="2023-09-13" version="1">MDISPAERQKYAEIFQSLNPVGGYITGVQARQIFMNSGVHVVKLGQIWDICDIDKDGNMDFDEFCLALRFVYASINGEISDIPQSLPPHMIPPSKMQYFGGGAGNLGYNQSYMQQAQPTGAYPTSSQSYGQQSSNYSAISELDTVNHNLSDDFDWYIAPSDRSNYESIYSNNVQLSSGEVRMSQFEELYQALQIPRDDINAAWSLVNVHSAPQIGKEQCIVFFHILNSRRLGKRVPPTLPGSLRTSFLGSSNYDLSDNYSVNEIQAGRPSVPLSFATNSAFSSHKGHAMADDYLSRLNQKGHVANETQAQEERLKHELENIKRQIEEAELRSNSNRGDINLAKKELQELLAYKQQQVLNDDESILNRQLLDQDREIQRQRDALKQLDKVMQGLREQKDLLETHLADSEGELRESQREIESVRGSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZ51</accession>
    <name>A0A9P6MZ51_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Tryptophan--tRNA ligase, mitochondrial</fullName>
            <ecNumber evidence="3">6.1.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Tryptophanyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BGZ80_006492</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>tRNA(Trp) + L-tryptophan + ATP = L-tryptophyl-tRNA(Trp) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24080"/>
            <dbReference type="Rhea" id="RHEA-COMP:9671"/>
            <dbReference type="Rhea" id="RHEA-COMP:9705"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78535"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.2" evidence="3"/>
    <dbReference type="EMBL" id="JAAAID010000320">
        <property type="protein sequence ID" value="KAG0018972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZ51"/>
    <dbReference type="OrthoDB" id="15808at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004830">
        <property type="term" value="F:tryptophan-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070183">
        <property type="term" value="P:mitochondrial tryptophanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00806">
        <property type="entry name" value="TrpRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000082">
        <property type="entry name" value="MSW1p Mitochondrial tryptophanyl-tRNA synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.240.10:FF:000002">
        <property type="entry name" value="Tryptophan--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.240.10">
        <property type="entry name" value="Tyrosyl-Transfer RNA Synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00140_B">
        <property type="entry name" value="Trp_tRNA_synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002306">
        <property type="entry name" value="Trp-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024109">
        <property type="entry name" value="Trp-tRNA-ligase_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050203">
        <property type="entry name" value="Trp-tRNA_synthetase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00233">
        <property type="entry name" value="trpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43766">
        <property type="entry name" value="TRYPTOPHAN--TRNA LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43766:SF1">
        <property type="entry name" value="TRYPTOPHAN--TRNA LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01039">
        <property type="entry name" value="TRNASYNTHTRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 12" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00069760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU363036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0018972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="391" mass="43177" checksum="AAEE22A38AC6DD3C" modified="2023-09-13" version="1">MTLTAHSLAFTKQVFRGVKSVDLCKVAIASSQKVQNVRSLATQSKPKATPITFSGIQPTGHPHLGNYLGAISNWVTLQEEAYQAKETVLFSIVDLHAITLPQDPEKLRKERREMAITLLACGVDPKKCILFEQSKVSGHAELTWLLNCMTPVGWLARMTQWKAKMGVTKGSQSLEDVEATKGLQLGLFAYPVLMAADVLLYKATKIPVGEDQIQHLELARDVAQTFNKMVKTPFFPLPQPKITETKRIMSLRDPTNKMSKSDASDQTRINLVDSPDLISSKIKRAVTDGIRGISYDQTNRPAVANLIRIYAAMKRVSVEDVVREHADSSTAAFKEALADVLITSLKPIQDEMARLEKEDAYVQSVLDDGAAKAAEIAIPNLQEAQRLLGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZD5</accession>
    <name>A0A9P6MZD5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Sla2 Src-like adaptor 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">SLA2_2</name>
        <name evidence="9" type="ORF">BGZ80_005645</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLA2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000278">
        <property type="protein sequence ID" value="KAG0019544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZD5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030136">
        <property type="term" value="C:clathrin-coated vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035615">
        <property type="term" value="F:clathrin adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032051">
        <property type="term" value="F:clathrin light chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043325">
        <property type="term" value="F:phosphatidylinositol-3,4-bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080025">
        <property type="term" value="F:phosphatidylinositol-3,5-bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048268">
        <property type="term" value="P:clathrin coat assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17007">
        <property type="entry name" value="ANTH_N_Sla2p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1410.10">
        <property type="entry name" value="I/LWEQ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011417">
        <property type="entry name" value="ANTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013809">
        <property type="entry name" value="ENTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035964">
        <property type="entry name" value="I/LWEQ_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002558">
        <property type="entry name" value="ILWEQ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030224">
        <property type="entry name" value="Sla2_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10407">
        <property type="entry name" value="HUNTINGTIN INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10407:SF15">
        <property type="entry name" value="HUNTINGTIN INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07651">
        <property type="entry name" value="ANTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01608">
        <property type="entry name" value="I_LWEQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00273">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00307">
        <property type="entry name" value="ILWEQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109885">
        <property type="entry name" value="I/LWEQ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50942">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50945">
        <property type="entry name" value="I_LWEQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ENTH" evidence="7">
        <location>
            <begin position="6"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="I/LWEQ" evidence="8">
        <location>
            <begin position="802"/>
            <end position="1046"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="265"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="1005"/>
            <end position="1032"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0019544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1048" mass="119911" checksum="BCF64CF89F62DD8D" modified="2023-09-13" version="1">MTRPLNRDKADTELHQHIRKATNQEETAPKQKHVRACIVYTWDYHSSSPVWQGFRTQPILGDEIQTFKALISVHKIIREGHPITLKEAQNETDWLDQCARSTHQFDVRGYGTLIRSYVDFLHSKLRYHRNHPEFNGTFDYNEYISLKGIDDPNEGYETISDLMNLQDQIDQFQKLIFANFRPSSNNECRIAALVPLVQESYAIYQFATSMLRAMHRRTSDPDGLALLRQRFNAQHYALLKFYYECSNLKYLTSLISVPKLPQDPPNLIGGDSPPLLPTRRAVSPKPVETSRPSSPGVDWAEQQREIARKQREYELEQQRLQQQRELEQQQQQMEALRLQQEFDEQKRLQIERERLQREQLQREQVQRQAEGRLAELEQNVLTLRGQYERDQMLIQQYDRRVKALEQEMQLINMNAQQQLASKDDMIRSIQDQINVWKSKYEALAKLYSQLRQEHLELLTKFKAIQLKANSAQEAVDKMEKMQKEIKDKNLQMADMVRERDRAKNELLRWQNTQNDEVARLKRDLEMANGRVEDLGRSKSSEVGAMVAKFNKEKQDLEDLANRHLREIESLQRQVEDQKMDIERMQIENEEEKSVLEKGLDETLLELATVRDGQSEKSSVLQGRLDAMSSSHKHKMAQIFDSIMETCIGKIEESIYDLESPTQLGNQTATPEFTLSMIEKAHTASTEFELALLQYLRPSHDINQVDAIRAALNLSQTIVDVLGNAKGITRLAKKDEDADDIIRHAKSSALAAQEFFTNVTSTRLGGLSPEGSIRTIERSNEGVQAAMERLAKATEYLIPKSSQLDPSKMDLGDVVEMEMGNAARTIEEATAKLQALMSKPKNEGLSAIEIQVNASILESAMAMMQAIGHLIKCATISQQEIVAQGRGTQTNAAFYKKHNRWTEGLISAAKSVAMATTLLVETADGVISKTHSMEQLLVASNEVAAATAQLVAASRVKANIMSKAQDNLERASKAVTEASRALVRAVKTIMDREMKERESAVDYQNMNAHEFKIKEMTQQVEILKLEKELTLARRVLGEMRKVSYHQSDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZP0</accession>
    <name>A0A9P6MZP0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Heat shock 70 kDa protein 12A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">HSPA12A_3</name>
        <name evidence="1" type="ORF">BGZ80_005174</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000257">
        <property type="protein sequence ID" value="KAG0019849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZP0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10170">
        <property type="entry name" value="ASKHA_NBD_HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187">
        <property type="entry name" value="ALPHA KINASE/ELONGATION FACTOR 2 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187:SF5">
        <property type="entry name" value="HEAT SHOCK 70 KDA PROTEIN 12A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0346">Stress response</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0019849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="491" mass="55020" checksum="0F6AE99679C8395D" modified="2023-09-13" version="1">MVEWGWKSKLLMESPAASKYTQLYQYKPYLDENVAMTPWREKVSVANAISDYLRALHEYAADKILQEFGRSYSRNSFRYCLTVPAMWSDKAKDVMRKAAIRAGLITAFDHPDRLTLVSEPEAAALYCEKACKQYDLGHGDRFMICDAGGGTVDLIVYEISSTSQGRRLSEVTKGHGATCGSMFIDLNFGNLLIKKFESQDAKIPKNIIPAMVDTFAYNHKPQFGEDDELYLALPRNSFFDDIKDPKSIGIDGGFMSLKESELKKVVFEPVVKQVLTLIQEQLNNAKQCSAIFMVGGFGSSNYLLKRVKQEFGSVVNTISAPNRPELAVVCGAVYAGLNPKMVTARITRLCYGTDAGMNFEEGIDPERLKLRKSSGPLCTGRFSTFVRKGQKVQVNECVTKLYSFTKNKHGTSTYSTGIFAIDGDPPRYIDDVGVSELAKISISDPFTPSDQIGHKVSVEMKMYFGLNEIRTEIFVQGTKYIKQLKFDDRDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZP5</accession>
    <name>A0A9P6MZP5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AIG1-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_006852</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000341">
        <property type="protein sequence ID" value="KAG0018700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZP5"/>
    <dbReference type="OrthoDB" id="8954335at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006703">
        <property type="entry name" value="G_AIG1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04548">
        <property type="entry name" value="AIG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AIG1-type G" evidence="2">
        <location>
            <begin position="9"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0018700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="243" mass="27133" checksum="2981CF48CAEFB731" modified="2023-09-13" version="1">MVVHPNNKKIIFVGKMGVGKSSLTNMFVQGDLFKKNVREVSNSADAVTAEIEVVDGLGWTVCDTVGLGELQGKGDSKKDEAMDLLVRVLREGKLGFHYIAYVIKQGRLRTKEHAELFDLFKKTFAGAEKNFILIITHSKESWAEKNKTAISDIFGDIPVFTCDFPFDEDEAELDEHARKESLRKLVKGLSALELKPIAPKLSRESTADEAAKKQFAESFERFLGIGLNILGFVVRILIELYAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1A7</accession>
    <name>A0A9P6N1A7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Arf gtpase activator</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_004584</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000232">
        <property type="protein sequence ID" value="KAG0020223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08204">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000252">
        <property type="entry name" value="ARF GTPase activator (Csx2)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.150">
        <property type="entry name" value="Arf GTPase activating protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045258">
        <property type="entry name" value="ACAP1/2/3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037278">
        <property type="entry name" value="ARFGAP/RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001164">
        <property type="entry name" value="ArfGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038508">
        <property type="entry name" value="ArfGAP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004148">
        <property type="entry name" value="BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23180:SF160">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN EFFECTOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23180">
        <property type="entry name" value="CENTAURIN/ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01412">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16746">
        <property type="entry name" value="BAR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00405">
        <property type="entry name" value="REVINTRACTNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00105">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57863">
        <property type="entry name" value="ArfGap/RecO-like zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50115">
        <property type="entry name" value="ARFGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PH" evidence="6">
        <location>
            <begin position="755"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="domain" description="Arf-GAP" evidence="7">
        <location>
            <begin position="971"/>
            <end position="1112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="78"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="381"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1155"/>
            <end position="1251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1340"/>
            <end position="1393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1490"/>
            <end position="1540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1580"/>
            <end position="1680"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1699"/>
            <end position="1730"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1775"/>
            <end position="1798"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="393"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1164"/>
            <end position="1195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1206"/>
            <end position="1226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1349"/>
            <end position="1367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1497"/>
            <end position="1516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="1526"/>
            <end position="1537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1591"/>
            <end position="1604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1605"/>
            <end position="1630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1637"/>
            <end position="1650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1663"/>
            <end position="1674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1782"/>
            <end position="1798"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0020223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1798" mass="197240" checksum="F0BA66AAEF6952E0" modified="2023-09-13" version="1">MDTLKPSQAQSTLFQSDSTKYGRVRADSITHLVFQRLLSTVAISTITLHDATTSPVMSLAVDQTSSEVSIKFPIQDTMEYIQDPEDSRQRRNSPVSSDSMPANKELPLLLLKIQAREGLRLSFELTGHILDSVQPWPGAQTGTEEPNLDLDKCQAQDCDQDHAIGKEQHTTGPNDRDLIRQNLQSIATLENRGNAILTPSDNEVTSTNAGPCVTTTPNEISTKRYAPTIYFAETQTEQSMHDLCSEIAFQQQLLESPGSISIVQSASLSENNPPSKVHSWEWIYESEDRSERRSQSHKAVFGFMARNHSTGALEILSMFSLWIQHGPDSTVNNGVRSSSTPQNNSAWNARHWRRISTPEKNSNASRLPSFWSRLPAFPPSHSSLPSLQQEAPSRADKEKAPSRADKEKAPPRVDKEKALDESFVPIRISSQMPLANGTEDGPLFRATVVECEQHIRNMKNASKRILKAAYTVLETRKAWLAAEEAFAKELELMRPAESLVDQYWRPVSEHLAEQSEMLSQHMRDLLIEPFTRFYGVDIKAAELHRKAFEEESKEYYSFLSRYMGMKQDNTQKKRDADAKHEKRKRNFELKRLEYWNFLIDMRAGGSKGDELCLHLTNYTEKHCQNVTDMGVIAGELQSSLSAIVTANKQRQERNIGLQGANGTSTTSLPLYKPFGRNSAGLVLAPTAPSTASNASLDSPRTPYFERDSFDLQLEPEVVVHSSMYSAPHNSNGSTQSITGIRDLEHQDIDAGLALGRRKEGFLFATSRPSTHGGTVLEKPNINWHKYWCVLSEGQLHEYSHWKKGVTQPHIDPINLRIATVRSCRDQDRRFCFEVITPKFRRVYQAMNADEMNSWISVISNAIQGLLNGTSSCRNLNLEYMSSGYKVSGSPDGKGLMAGLSGMTRPSVEQVLNATSLPTSLQDRVLPGQAFGRKRGGNAVDGLNELGQIIQPIAAQANLSGDDQKDSNQLGVKLLCLMREQHSANTVCADCGAKNPDWCVINLGILVCIECSGIHRSLGTHISKVRSLNLDTTSYTKDLFEFIRSVGNNVSNEIWEANLAHSKDQQQELGSQEQTTKVIFRKPVVNDPREYKIAFIRKKYAERAFMNQQQYPGTGDKVSRATDALFRAVAANDIPAAITAFVAGANVNAVQRADNECDSGPFVEQDSSPVPTAQQKNTEDTLNSGDNPNTMNSPTPEESVLQPSALDDSTTSETSSQLSRSTESYAVSMTDRNEEVTSTDQRPVGTLEIRPRPLGGRPISSVMVLQTTPLLIALRHGVPFTLEEGFEVYPLAEFLMQNGAASNMSMEVKLLNAEPATALMEPSGPTHMRKVSRVKPEEFPEGMIERDAPLQTSSSIGSRLSAGTSSTGPAAVSPGRASLRSSESNDAEVDKTANRRSVGQIVELRGEDGVSAMEYLRSKGIARGDLAPITVTSPPVVATSNINASAPIGNPYWKEGAKLRPSSLKDMNIASMSTPSMSSVLTNGLTLTPRLRSSRSITTASDSTTGSSTANNGDGSTANQRDHRILPPNPLTSYPPPARYNNQDIATLFQKRRGSDSGTGSGFFSSMKASSFSVKDKEKAAAKAHARRSGDFSMFRPPSMMSSLSQHSEMSTNTGISHYTESSPAAETGSSFFPEGYQLSSDATEANNGSMSIADMTLHPDSNGDISNGGTPSRTQKVKASLTKSIRLSARYIRGSVIKDDSKAKSKGDTQSGISMSAPRLDSDDEDMGGDGEELTMAELLALQDQNPNQKGQQRHNILLHPSTATNRISSKSFFSSMSFSSTPNLSQKQQQPSSGIHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1S3</accession>
    <name>A0A9P6N1S3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HCNGP-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000206">
        <property type="protein sequence ID" value="KAG0020619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1S3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012479">
        <property type="entry name" value="SAP30BP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13464:SF0">
        <property type="entry name" value="SAP30-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13464">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATOR PROTEIN HCNGP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07818">
        <property type="entry name" value="HCNGP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="346"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="132"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="367"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0020619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="404" mass="43557" checksum="975A58531B5BA53A" modified="2023-09-13" version="1">MNRGIGLVAYGDSDEESSGEDTPMTAAPPSKTKELKESGMAINSHFLWILLHETLHDSSQKTGGVVDSVNKDSERPTLQDTIAARSIANTRPSGNESLNKIASTNLMKQGLAVSSENIHTDPSTDTTANDGSSSSNRHSFIRSQSGTPLPPDHSAAADVFNTPTGGRSPQVPSTERVPIADESRAVESGDDKDGDDGEIGSRRWHNNRVNLMKSLLRPKPIPGVENFGIPPNPEGEVNPDVQAKMEQFHHVKVTRGIHFNQSLMKNKNFRNPHIYASLVELVALDETGSNFEKSEFFDFKGYGPESYASGIAEAQKQASEKLAQQQAAARSQLQFVPGSTVGSGVGFPSAAPVVKPQQLPASRLQQSLSNSSVTTASASTQRNRKSKWDQSSDDPSGKKSRHFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N232</accession>
    <name>A0A9P6N232_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">AP-4 complex subunit beta-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">AP4B1</name>
        <name evidence="8" type="ORF">BGZ80_000482</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the adaptor complexes large subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000110">
        <property type="protein sequence ID" value="KAG0022341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N232"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030117">
        <property type="term" value="C:membrane coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026739">
        <property type="entry name" value="AP_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11134">
        <property type="entry name" value="ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Clathrin/coatomer adaptor adaptin-like N-terminal" evidence="7">
        <location>
            <begin position="5"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="406"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="461"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="571"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="407"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="423"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="470"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="579"/>
            <end position="588"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0022341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="898" mass="99709" checksum="7B194EDC10ADC040" modified="2023-09-13" version="1">MDVAELSEAFKDQSLQPSNHAQLMQRMQELMGQGMDVSSLFATIVSSTSTRDISVKKAAYAFLAKYGSTNEELCFLSINTLHQDCADLDPIVRSLALRTICSLGQRSVLRFMLQPLSKGFQDKNAHVRKTAAMACISIFELDPVFVLESEIVDKLYGLLRDRETQVVVSAILALETILVDEGGIVINYNIAAHFLQRYKDWSPSQLQIILGVLCRYKPQTNDEIYEIMNDVDDGLQNPSLAVQMATLRLFIWLCQDLTEIQEDLQKTIEETLIKHLGSPVPDLVYASLCHLSLMIETTGRLHHNTPEHLSAVLCKLNDPVAIKLQKFSLCATIAQKSTSVTVATTLGSTNVSTLILDHLCHVAAMRDIVNLVQKSHRTKTRIDRHSITDNLEVACRAIETIGKIGTFQHSSQSQEKQPMARLSPTSGSQEDGQSGRSISKSCIDRLFQLLILFSSMEHTLEKPRSEGQKDGSSNMKKSQHGQADNSWTHTNIADLGLDESQVALLLSTVLLTIESCWQYELEARQRRTEETARMGGIFEPLQIKSLGILLLRHLDQGELDRLAKKKKPLRFRYDDGNDDQPSQASSVYAHNGSPGDISRLARISGLRMLLLEESAQQLSLRKQIQINSSNPEDEGAKTKAQGIQEALGMRAQYALLLQQQVQDMVQSLDTTITHTTKSDQAFLLTRAEQIATLQLACHLVAFSIDQESEDAGMSTEIQSTDVDILKRRLDILGQAVDQLIPANTAPGSESENSPFGDDLVSFETVNPSTTSQQHDSQIRVQLESVSRDVADRARLVESLFLVPLLSSLASPSTLTDIPTPRSISQNNQFNSPIFKTDAYQKLVKQKFVDQFGIKGKRSPFATATVENGAESDAGLDMDKLILYDWCFQVGFNTLALTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2D5</accession>
    <name>A0A9P6N2D5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Mediator of RNA polymerase II transcription subunit 8</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Mediator complex subunit 8</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">MED8</name>
        <name evidence="3" type="ORF">BGZ80_002931</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Mediator complex subunit 8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000175">
        <property type="protein sequence ID" value="KAG0021169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N2D5"/>
    <dbReference type="OrthoDB" id="5568181at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019364">
        <property type="entry name" value="Mediatior_Med8_fun/met"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10232">
        <property type="entry name" value="Med8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0010">Activator</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="172"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="281"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="174"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="203"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="282"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="335"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU364144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0021169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="351" mass="39027" checksum="1E4979C47FFEF3B3" modified="2023-09-13" version="1">MNTTFPQTEINVEALENVKTRLFQLQESIVFFLRSINPDIIPGTVSWTELHSKFNVLIAKYLHLTNLVNDPHNTLLQSYTVFPNEAPANDQHVQNLSVLLRTKLFPELEQEAEDRISDGSIPGLVNSSGSAAEDRRILQALKLKVTMHDALCQAADEILENQRDMVHVKMRYESDDEDEDDDNDGDEPGEATATEDGENTKTQSKAQPSSNSNSKSKQYSNDVIPVDDFAIGNLDSASSVRYMSDWGGALHDMDGYSSGSDGCIDADELDDSYFEAQRQVIDSDEASDEDDMESIQSEEDIEAEADEESGDVFIEVGAESQDVRAGSSAMTTTEDTFEEEFSDEEDMEEVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2F7</accession>
    <name>A0A9P6N2F7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Anaphase-promoting complex subunit 4-like WD40 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_002808</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the WD repeat AIP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000171">
        <property type="protein sequence ID" value="KAG0021240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N2F7"/>
    <dbReference type="OrthoDB" id="2306at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030864">
        <property type="term" value="C:cortical actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030042">
        <property type="term" value="P:actin filament depolymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000102">
        <property type="entry name" value="Actin-interacting protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000167">
        <property type="entry name" value="Actin-interacting protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024977">
        <property type="entry name" value="Apc4-like_WD40_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19856:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19856">
        <property type="entry name" value="WD-REPEATCONTAINING PROTEIN WDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12894">
        <property type="entry name" value="ANAPC4_WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50960">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="54"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="185"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="231"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="319"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="domain" description="Anaphase-promoting complex subunit 4-like WD40" evidence="5">
        <location>
            <begin position="451"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="482"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="528"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="568"/>
            <end position="603"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0021240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="603" mass="64394" checksum="C2CB4C128472483E" modified="2023-09-13" version="1">MSAIRSSIFACSPATTRGQGVHLDTDPKGESILYTNGKTVFIRNIEKPHIAKEYTQHNCNVTVAKYAPSGYYIASGDERGNVRIWDTVGDEQILKLESHAISGKVNDIAWDGESKRIIAVGDGREKFAHAFMADSGSSCGEIMGHSKVVNTVAIRQTRPFRAVTGGDDNTLVFSNGVPFVFNKTIHDHTRFVQEVKFSSNGEMFASVGSDGKIFLYDAKTGDKLKELSTADHGHTGSIFALSWSADSSRILTSSADQTAKIWDVETSSVVNTFDLSSQDSTFHGQQVGNVWKGSNLVSLSLSGDLNYLDPSTSKASRVVQGHQKAITALAVSNDKKTLFTGSYDGRVMSWDESSGVATPLKEASHGNQVMQMASSGAQLISAGMDDTIRISSKSAPSDVTVVSTNALPKSVSSSDDQTIAVATENEIQIIQGGKKAGSLAVECSATAVAINPQGKVVAIGGQDTKVYIMKLEGNKLTTVHTLVKNKSPISALAFNSEGNLLAAGDNSGKIYVYDVATGEAVVHQWVFHTARITSINWSPSGRYAVSGSLDTNIYVWSVEKPSKKIAILNAHALSVSGVAFIEEDKIVGTGADACVKTWKLTHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2L5</accession>
    <name>A0A9P6N2L5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_011731</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000098">
        <property type="protein sequence ID" value="KAG0022585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N2L5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1720.10:FF:000013">
        <property type="entry name" value="Related to multidrug resistance proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004638">
        <property type="entry name" value="EmrB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00711">
        <property type="entry name" value="efflux_EmrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF191">
        <property type="entry name" value="VACUOLAR BASIC AMINO ACID TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01036">
        <property type="entry name" value="TCRTETB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="58"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="126"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="151"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="184"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="212"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="252"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="277"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="321"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="360"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="386"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="417"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="448"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="521"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="61"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0022585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="564" mass="60821" checksum="55DD6B283A7E156B" modified="2023-09-13" version="1">MGAQEQAPSISSSNTYMASNITTDPQNPLNKEVSIDIPSSEANNDSDGGVVTLPFKELIVVFIGLMLGVFLSSLDQTIVSVCTTKIANEFHALSDIAWVGTSYLLTSTSFQPLYGRFSDIFGRKSTFLFSITVFLIGSALCGAAQNMTWMIVARGIAGIGAGGVMSMVMIIITDIVSLRDRGKYQGMIGAAFGFSSVIGPLLGGVFTDKASWRWAFFINLPIGAITVATAIKVLRLPHTRGSFKEKIKRVDFFGSLTLICGLVMILLPLNWGGSTHAWNSPLIIGLFCGGFAILVIFCLIEWKQAAEPIIPFYLFKSRTNTAVFLSYFFFGMAFFGVMFYMPLYYQIIRQESATTAGLEMLPLIVGLLIASITSGALVSKWGQYRPFIWSGLTIAAVGIGLLTLLEENSSRGAGIGYLFVVGLGVGLSIQTIAIAIQSSVAPKDIAVATANATFFRTVGSVFGVAVIGTVFNNSVKNNMAPLILINPDVANVLSDSYLAPTFGAEMETQILHAYMLAIRTGFRVCIPFMCLAFVCSLFIEKNKLHKTDTPIAMDATNSTRELGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2W7</accession>
    <name>A0A9P6N2W7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Lipoyl synthase, mitochondrial</fullName>
            <ecNumber evidence="9">2.8.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Lipoate synthase</fullName>
            <shortName evidence="9">LS</shortName>
            <shortName evidence="9">Lip-syn</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Lipoic acid synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_010838</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>[[Fe-S] cluster scaffold protein carrying a second [4Fe-4S](2+) cluster] + N(6)-octanoyl-L-lysyl-[protein] + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine + 4 H(+) = [[Fe-S] cluster scaffold protein] + N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + 4 Fe(3+) + 2 hydrogen sulfide + 2 5'-deoxyadenosine + 2 L-methionine + 2 reduced [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:16585"/>
            <dbReference type="Rhea" id="RHEA-COMP:9928"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:14568"/>
            <dbReference type="Rhea" id="RHEA-COMP:14569"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:33722"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:78809"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="EC" id="2.8.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="9">Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="9">Protein modification; protein lipoylation via endogenous pathway; protein N(6)-(lipoyl)lysine from octanoyl-[acyl-carrier-protein]: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the radical SAM superfamily. Lipoyl synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.8" evidence="9"/>
    <dbReference type="EMBL" id="JAAAID010000080">
        <property type="protein sequence ID" value="KAG0022923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N2W7"/>
    <dbReference type="OrthoDB" id="3231at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016992">
        <property type="term" value="F:lipoate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009249">
        <property type="term" value="P:protein lipoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01335">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000036">
        <property type="entry name" value="Lipoyl synthase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00206">
        <property type="entry name" value="Lipoyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaA/NifB-like_rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031691">
        <property type="entry name" value="LIAS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003698">
        <property type="entry name" value="Lipoyl_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00510">
        <property type="entry name" value="lipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004019">
        <property type="entry name" value="PRK05481.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009544">
        <property type="entry name" value="PRK12928.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10949">
        <property type="entry name" value="LIPOYL SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10949:SF0">
        <property type="entry name" value="LIPOYL SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16881">
        <property type="entry name" value="LIAS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00271">
        <property type="entry name" value="lipoyl_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01058">
        <property type="entry name" value="lipoyl_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6 9" id="KW-0408">Iron</keyword>
    <keyword evidence="7 9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Radical SAM core" evidence="10">
        <location>
            <begin position="152"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="384"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0022923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="422" mass="46462" checksum="13204D7AB585BB9C" modified="2023-09-13" version="1">MSSLKFASRALFSRSVSHNARPFAQSSAVMAVRNYNATVVKDTPPVKKSKFADKLANGPSFDDFVGGNQKLSPEEALELKETVVDQQKAAAAAEATGKPAKRAPKQRLPEWLKTPIPAGENYTKIKKNLRELNLHTVCEEAKCPNISDCWGGGEHQTATATIMLMGDECTRGCRFCSVKTSKTPKPLDIHEPENTAEAISRWGLDYVVLTSVDRDDLADGGSAHFAETIMKLKQKAPKILVECLTGDFQGDMECVARVATSGLDVYAHNIETVEALSSYVRDPRAKFRQSIAVLAHAKKAKPGLLTKTSMMLGCGETEAEVIHAMDELRKADVDVLTLGQYMRPTKKHMRVHEYVKPEVFERYQKLAEERGFKYVASGPLVRSSYKAGEFYISNILKKERDLGVPVVGNDAVVKLTDAGIRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3H9</accession>
    <name>A0A9P6N3H9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_000618</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000113">
        <property type="protein sequence ID" value="KAG0022284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3H9"/>
    <dbReference type="OrthoDB" id="419768at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005544">
        <property type="term" value="F:calcium-dependent phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010828">
        <property type="term" value="P:positive regulation of D-glucose transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090314">
        <property type="term" value="P:positive regulation of protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031340">
        <property type="term" value="P:positive regulation of vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072659">
        <property type="term" value="P:protein localization to plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08688">
        <property type="entry name" value="C2_KIAA0528-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037785">
        <property type="entry name" value="C2_C2CD5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038983">
        <property type="entry name" value="C2CD5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057815">
        <property type="entry name" value="C2CD5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056430">
        <property type="entry name" value="C2CD5_YbjQ-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056431">
        <property type="entry name" value="C2CD5_YbjQ-rel_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37412">
        <property type="entry name" value="C2 DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37412:SF2">
        <property type="entry name" value="C2 DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23025">
        <property type="entry name" value="YbjQ_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23028">
        <property type="entry name" value="YbjQ_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23128">
        <property type="entry name" value="YbjQ_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2" evidence="2">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="308"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="667"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="856"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="965"/>
            <end position="1056"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1175"/>
            <end position="1254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="308"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="856"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="989"/>
            <end position="1011"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1012"/>
            <end position="1028"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1042"/>
            <end position="1055"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1175"/>
            <end position="1184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1185"/>
            <end position="1203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1227"/>
            <end position="1246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0022284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1254" mass="137301" checksum="51AD36A591DC3D1D" modified="2023-09-13" version="1">MPCILKIRVIGARDLPVMDKASDLTDAYVEVRFADLEAQRTSVCRKTLNPVWNEDFRFEVTDDADLQNEPLELKVLDYDAITANDSVGSVFIDLNPLLPINSPWQIAGWFPIYDTIRGVRGEVNVQVKLQFFGDVNPFKDSSAGIMFFSTTSLPAGYQIVAMHGFVDAIVNEDDPEYHWSDSFRTQRSSNEARQRLLFRLSGQLRRLLGKETLDMGGNAVLGYQQCFDLESEEHAITARAVGTAVKIAMVSNPTSQASDKPQPITINELDTEDILSSTLDNDQLSSPIYPGANADSLVLASAMKRRGSSMSSESSSSTDSAPSVASGTKNSINNYKYLEQQIFTLHEFPPGTVFNLGGIVSARSVKLIENDDVETRDAWWDELRDEIKSHARVLGCSHIIGYQEAATINDELIVLSAVGTAANLDMTAFTPGFFDQNRNLSRSGSISRSYVDNPLDNLSTSVGGARASFQNSLKEQQWLDMLAKRKSKRKQPSACRMCHIPFHRKSSPFPMSLVKCQKCKKKYVPEILLSTVEPPAELGVVGQSAFVEAHVCRAKKRKDGESNATIVSDAIPFVEYDLHRQLMYKLKIHGLNAVFGLRFQLTVGDSLIVAVACGTAMYLSALPTPPALRISRNLDVIDEEDKKLLEMQRKIMDLSETNRRNLEAAKLREQEDGERSPLPNLTDVAQTGHTEEDSSGSSSDSDDEAEKDNYQTNVVIQIDDDADEDLMAVLLDPVFTDGFLLCSTETLPNHPYFVSTDPMIPDNAHLITTVKQGHINIISHHPNRQLAALFRSIYEDLRFRLSYFTDCVLAGITYNIQLPRSNEVQIQLTAVALGQQRQTDGLEPLGIPITLSPWRSTPGSAALSTSHSRSESENGPLPVNPSPIPTRGVPVEDSMVFLMDECQLAPKHTPAPTQSTAPIGAAADLNTRAGLPNQIATTSALSGHISASSVTSPITPVGDQHSRFIPTDSEVSTPIDGPSRQSLYRLPDNQGQFSSTMNSSLAPQPSLNNHFSPSNGNSNSEGMSGASNMKTGPQHNRHVRQKSVSSAMSRQGQIEESSRVALLPMMPADRPFIEMTPLSFIPGRTPTRYLGKLSLHFVKETHILHDSTVSSGMGGFVHVFLMEIQAVARSHVAALGGDAIVGLRVDESFFQESVKNQGYALISISGDVVGCALTDQDSNASQSSDTEDEEVEDKDKDEDEDGDDNHRNRLDGTHVLGSVGDTPIISGWQSNQSMESIDIPSSTLPVTETVPEAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3L8</accession>
    <name>A0A9P6N3L8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_000309</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000106">
        <property type="protein sequence ID" value="KAG0022415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3L8"/>
    <dbReference type="OrthoDB" id="1049195at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000145">
        <property type="entry name" value="Putative RNP domain-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050374">
        <property type="entry name" value="RRT5_SRSF_SR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003:SF3">
        <property type="entry name" value="FI21236P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003">
        <property type="entry name" value="RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="128"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="236"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="391"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="205"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="310"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="57"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="101"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="341"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0022415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="467" mass="51810" checksum="6DAEFB52AEE82EF6" modified="2023-09-13" version="1">MEMHTSNGSLNNDPVDVLLPNDMDVMDDMHESHHRRSSYHHRDDDNGHGVITGVDGRLGDDGERADHEREREREHESNLDRGHYEGRDQYNRDNKYDNNRSHRSGSGRRARSRSPVRASAGSGDVRDRRVYVGNLSYDVKWTNLKDFMREIGPVAHADVLLGHDGRSKGCGVVEYQNADDAKAAIRKLNDVVLMGRPVFVREDREPDSKIGFSGGKATSSRNRDAGPSRGAGGPTRQVYVGNLPYSVNWKDLKDLFRRAGAVDRADVFMNRDNRSKGSGTVSFETSHDVGRAISMFNGYDWHGRRIEVREDKFGPPSGGPSRGPPASSSRYDPPPRDYGRGDSYGYGHSSGRPSRGHDVYNGSGSTSHGDFRDSDFNMADIPSGPAAGSGDQIYIRNLPLTTTDQDLKDLFRTCGPIRMTQMLDSTGRSSGSGIVRFELFESAHKAVTKFSGYVYGGRSLEVVYDRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3N5</accession>
    <name>A0A9P6N3N5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box/LRR-repeat protein 15-like leucin rich repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_000486</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000110">
        <property type="protein sequence ID" value="KAG0022345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3N5"/>
    <dbReference type="OrthoDB" id="421226at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057207">
        <property type="entry name" value="FBXL15_LRR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318:SF95">
        <property type="entry name" value="F-BOX PROTEIN YLR352W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25372">
        <property type="entry name" value="DUF7885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box/LRR-repeat protein 15-like leucin rich repeat" evidence="2">
        <location>
            <begin position="391"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="233"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="570"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="199"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="579"/>
            <end position="598"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0022345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="727" mass="82627" checksum="D4FF80A9D131B589" modified="2023-09-13" version="1">MTLEVDDGEESVTDVIQGSQIFNSHETGEEEDCENELDMVMSQQNEKQRDTSINDKLQPEILSLIFDQLADRPRTLRHSRPNAEGAISELKLRQVSRKDLLTAISLNLIHESDKQELMQWFEWRMKEKARRLKALKRRRRLVAERTRQNENPQLDESDEEDSEDEDDDDDSDSDESDNESDGANNDNNDSEDVLNNMEDLNEGPENDTEYDASDDETPLMKLVSGIDYLQSFLNPTGRDPQQLRRSRQSIEPTLSDTLSTTVARARRHQIAREVRQRLAQIRPFDGLPASLPLQTCGHWMQVINLQQEMPHPQRINPPPNMNNAPPAPQLHPLEHEEIQVPFQHHHHHQQHQPRSPHRRGLLASFINALTHNHFDDDDQFIDMVTRRSHPPVRLRSRREFVTDKTLQTILENCPRLCRLTISECHGITDEGFKLIRGSKCVAQGTLISLHMAGCYQITDQGLLNLVGESGDTQTQPRFESLDLAGCHGITDQGFIPLLRQCGNRLIQLRVHDCPNVTSESVFALAEHCPRIQWLDLGRSGKMTEAGLVHLASRCSELEWLSLARHHPNDRRDSGIQFDESFEEEEQGVQEEEEEEEDVTGNSGPGQEEKLITDHAISLICESCPKLHLLDLSYIPTITNYAIESLSRSARSLVYLTIIGCPGITSQSLYYLANLRNTSGKLGCITMGDALGISEKEIEQIMQGTLSGWQKSMVDETTLGNILGRNWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3Q0</accession>
    <name>A0A9P6N3Q0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006288</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000031">
        <property type="protein sequence ID" value="KAG0024063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3Q0"/>
    <dbReference type="OrthoDB" id="2412974at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0024063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="96" mass="11142" checksum="E89F8DC5A0E49325" modified="2023-09-13" version="1">MGETTSPWGIVGRDAMRAAGLSRFVPPPYMQPSFMSHARYRRKRSNDEEEGYDEEIDMDVLADEHHDSSVEYDYEFSEDDHSDDDAKNPPCSRRPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4P2</accession>
    <name>A0A9P6N4P2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Aldehyde dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ALDH3A2_1</name>
        <name evidence="7" type="ORF">BGZ80_000901</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000012">
        <property type="protein sequence ID" value="KAG0024600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N4P2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006081">
        <property type="term" value="P:aldehyde metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07087">
        <property type="entry name" value="ALDH_F3-13-14_CALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000003">
        <property type="entry name" value="Aldehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000004">
        <property type="entry name" value="Aldehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012394">
        <property type="entry name" value="Aldehyde_DH_NAD(P)"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43570">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43570:SF16">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE TYPE III, ISOFORM Q"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036492">
        <property type="entry name" value="ALDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="6">
        <location>
            <begin position="9"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="211"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR036492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR036492-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0024600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="441" mass="48252" checksum="618AC6504D0FB874" modified="2023-09-13" version="1">MGIENTPVSSIPKIVAASRASFLTHRTQSLEFRKEQLRALLRMISENQDDLSGAIKSDLGRPKDFEVLGCAKTCEFFINNLEALSENKKAHGLKDGDECYVRYSPLGTVLIMGTWNFPISLVLQPLAGAIAAGNVCIVKPSEVAEASANVLTRLLTKYMDPNVVTVINGAVEETTVLLQQRFDHIFYTGSTDVGRIVMAAAAKNLTPVTLELGGKCPAIITENTNLVDAAQKIAVWKSSNCGQICLTVDYVLCPKHLQEKLIQTVIATWKHSFGADPKASNAYPKIINKRQFDRLEKLLEAVKKQNTVVHGGRTDATRLFIEPTIVTGVSLSDEIMKGEIFGPILPIVPCENIDQAINIINQQEHPLGLYLFSSDKEHSERLLKETRSGAVVVNDIAVHYGNPSLPFGGVGNSGMGSYHGKYSIETFSHARAVFIRPQAHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N6Z0</accession>
    <name>A0A9P6N6Z0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">V-SNARE coiled-coil homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_003713</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat L(2)GL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000002">
        <property type="protein sequence ID" value="KAG0024854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N6Z0"/>
    <dbReference type="OrthoDB" id="19944at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045159">
        <property type="term" value="F:myosin II binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019905">
        <property type="term" value="F:syntaxin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006893">
        <property type="term" value="P:Golgi to plasma membrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15873">
        <property type="entry name" value="R-SNARE_STXBP5_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013905">
        <property type="entry name" value="Lgl_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042855">
        <property type="entry name" value="V_SNARE_CC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10241">
        <property type="entry name" value="LETHAL 2 GIANT LARVAE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10241:SF25">
        <property type="entry name" value="TOMOSYN, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08596">
        <property type="entry name" value="Lgl_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50892">
        <property type="entry name" value="V_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="176"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="V-SNARE coiled-coil homology" evidence="8">
        <location>
            <begin position="1188"/>
            <end position="1252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="501"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="605"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="720"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="871"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="727"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="874"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="929"/>
            <end position="944"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0024854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1253" mass="137613" checksum="FEB1A8E12EB93B36" modified="2023-09-13" version="1">MTGAPDVAGYLELTGAVSVKMMVFQPGVPVLIVVDAKNAITVFDLIKRRHIFVRNARNIVTCIELLPGSNWLFHGLKDGTIDVFDVYKGQAVSYRIPNILPEGKKHSLVVSIKTHPTDNNQLLIAYNTGVVLWNLKQKAVMHTYIYEIPPGAMGGIVPGNGMPGMNESRYPYATVIAWRPDGQGFVSGYDDGCIVFWDVKQERPILARTIYEVQVNIPGIRPVYERNASQSMPIYQLSWCLQENREDSALIVAGGANQPGVYALNVFDFPSKSDYSCPRRHHTVTTESDILDFIVIPRDSPWFNGSLDPVSIVILTDHGGIKAFSFDATHTPQTIPSTLLFADPSLVLAKTYGQLPQEIYDRLVYGLSSSQKFAHPFRIPLRGVRLAQCDESRLCRDILVTAHSDLSVRFWEGASLRPLHHLTVELKQLFFKNRGEIAFLEFSVFSQVLAVGFSNGSWVYCKLSWNGDLSRQSSVTGVVREDPVNEALSPNFQKAMHLNNHDGLVGTEDPYSIPGSPTQQYSPAPHQPMNEPRETLPMYSPNDGQDRRDAAPMPHQDQYIVSPMPQHIQDHHDAQPVSPQEIPIVSVQPPDPLTLDNRECPSEGINHEPSYCEQAPSPSLPPRPEFVGSPSLPPCPEFVESPSLPPRPEFVEVSLPNGSEFLSVFKSGTHMGRINQIAVSGCGLVAVSDELYSLSITDTVTGRVLHVEDLKVVMLDRDKGSLLHPNDGQSDARSIQSDSRSAYSDTRSNNSDARSTQSDAHSTNLDAPEVSSHVRIEPNEFQRVGVVITSLEFVVSTTSEQDKVPSLLLVAGSSDGIYMIFSISGDDSPPMQPQTRQVKKVETFQTKERCLSVHTSIVNVISPSENTATAAMRSTTSISSESSAVTSHTDPTSLSPHAGGPDSFNYRVVSPPLSPKQNLGDGLGHVPSARSSNADVSSAEGGSTHMSPIYSSWKEAQGKLMSMAQQRLQYFICVSQYTIRVHMNCTSRRIHKIDLTLANENEQGVGGLSSRTGRIMAANVVHHGEAACILCLTESGRILLFSIPKLELIPLPVPNGELYLPILLEPERLRESIIHSDGRIFVPILKYEFRMYSLWGHDRWVHTPQGLVQEQSAESSNYVQLYDHGVQIPPRPPTPVAPGTVAGWFGFGGAAPEVPSQRELDEVLGGANYRPENPILKRAGFEGRPQGPHGDGVTASSGVSAVLGDTLQGLDERGKKLQDLGRKTEDMSAASNSFLDAAKALNDKNANKKWYEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SSC8</accession>
    <name>A0A9P6SSC8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Carrier domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_007266</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003695">
        <property type="protein sequence ID" value="KAF9996345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SSC8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043041">
        <property type="term" value="P:amino acid activation for nonribosomal peptide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.30:FF:000010">
        <property type="entry name" value="Enterobactin synthetase component F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.38.10:FF:000001">
        <property type="entry name" value="Non-ribosomal peptide synthetase PvdI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1200.10:FF:000005">
        <property type="entry name" value="Nonribosomal peptide synthetase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF1">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="4">
        <location>
            <begin position="206"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9996345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="538" mass="59869" checksum="0CF4DD834DDA09A8" modified="2023-09-13" version="1" fragment="single">ATGAITQLDRMPIGRPMSNTQAYVLDKHRNPVPLGVVGELYIGGPGVANGYLNRPDLTAERFLPDPFSNVPGARMYKSGDMVRYLPDGNLVFMGRDDDQVKVRGFRIELGEIEERLAEHPQVREVIVLAIGESSGNKRLVAYVVAAPVDNLALTLHKHLAASLPEYMIPSAFVRMDIFPLTNNGKVDRRALPDPQEHAFVRQIYEEPVGEMEKVIANIWSELLGVSQISRHDSFFALGGHSLMVVKMLDHLHRLDLTVSVKTLFESPSLSVLAGALSKHQALTVPPNLITPETTRLTPEMLPLIDLTQSDIDRIIDQVPGGISNIQDVYSLAPLQDGILFHHLLGTEGDAYVLISHLAFQDRSLLDDYFAAFQKVVNRHDILRTAFIWDGLSTPAQVVHRHAPLSIVELTLDPTDGPIQEQLKQRYNHSNYRPDLTQVPLIGFATAKDADGRWILVQMLHHLICDHVSIEKMNGEVERILEDQASTLPTPSQFRDFIAQVRAGPTQDDHGVFFKEILADIEEPTLPFGLSEVHSNGDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SSR9</accession>
    <name>A0A9P6SSR9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Aldehyde dehydrogenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_006943</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003473">
        <property type="protein sequence ID" value="KAF9997685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SSR9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004777">
        <property type="term" value="F:succinate-semialdehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009450">
        <property type="term" value="P:gamma-aminobutyric acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050740">
        <property type="entry name" value="Aldehyde_DH_Superfamily"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43353">
        <property type="entry name" value="SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43353:SF5">
        <property type="entry name" value="SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="2">
        <location>
            <begin position="38"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9997685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="127" mass="14249" checksum="6B9C5DF04D8DC0BF" modified="2023-09-13" version="1">MTSVFNANGQLEASRWLKDPSLIKTAGFIDDKYVYSSSSGMKFSVYDPAQGTEIATFPDMGVEETEAAIQAAKRALPEWSQKTAKERSNVLRKWYDLILENEHDLGKIITWENGKPLTEAIGEVRYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ST02</accession>
    <name>A0A9P6ST02_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_006944</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003474">
        <property type="protein sequence ID" value="KAF9997677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ST02"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF191">
        <property type="entry name" value="VACUOLAR BASIC AMINO ACID TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="91"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="126"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="183"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="292"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="320"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="326"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9997677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="347" mass="37939" checksum="D289C3695450BAF2" modified="2023-09-13" version="1">MAVMLKLPRPKGNVWEKLATIDWAGTFFMATTTVFLLLPTNLGGNMFQWNSPLVITFYVLSIPSAIAFLYVEAKHAKQPVVPPYLWKNRNVATLFCLNIFMGMTFWTLIFYLPIYFQIIEHESATAAGLSMIPLEAGIFIASNVGGIVVSRFGKYRPGIFFGTFLSAVGICLCLLLAGTSSKAIQVVVLFICGLGIGPLFPCLIVGIQASVERKDLATVSALHNFFRMTGSGFGVAINGALFQNQLKNGLASSNVPQDIADIAISSAQRIVGLPIEYRGSVETIYLDSMKTVFKATIPMAAIMFLLTFNLRHIRLNTKPSASAEEAETKMTEEVINEKGSLDQKEAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ST09</accession>
    <name>A0A9P6ST09_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_006559</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003248">
        <property type="protein sequence ID" value="KAF9999459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ST09"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9999459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="55" mass="5950" checksum="C39BB044369ABA56" modified="2023-09-13" version="1" fragment="single">MDRSLPVDLAASPSVDVVDSPSADVVDSLQLMSLPLPHFVPFRSKNSRDTLQKAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SU58</accession>
    <name>A0A9P6SU58_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Mitochondrial adapter protein MCP1 transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_005898</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002902">
        <property type="protein sequence ID" value="KAG0002892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SU58"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055088">
        <property type="term" value="P:lipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039960">
        <property type="entry name" value="MCP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38409">
        <property type="entry name" value="MDM10-COMPLEMENTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38409:SF1">
        <property type="entry name" value="MITOCHONDRIAL ADAPTER PROTEIN MCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="155"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="199"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="236"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="74"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="246"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0002892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="320" mass="33911" checksum="6AB23E9DCAED40B9" modified="2023-09-13" version="1" fragment="single">MTSSDVVGNSSPVPEPYNVWADEHVNEDELDMEELIRIEEAAGISGTDSNLPTRYSAQTIRQKKGRQLASTMRTSPFGSTSISSESPSTSPPSSVPSSHKDDKSDSVIIGESAKVTPREVATSSYIGSGGGLGAGGTFPSVGLYQGLGRLQAFSAIAFGAFGFIHMVPPMLASVGGIELANKALIWGRVYYQTYGFEQVFVYGSLAIHIGTGLCKAIVRFVWKSKSYYASTRPVTDSQYADRPKSSKGATTITTPTTTTITSSKPGAKTSSTSSTSISGDRSGSGTAPGLFPYHRLVGWVLTPLVLGHMDTMRMTPIKVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXI0</accession>
    <name>A0A9P6SXI0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_002640</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001658">
        <property type="protein sequence ID" value="KAG0009198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXI0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040473231" evidence="2">
        <location>
            <begin position="23"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0009198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="79" mass="8046" checksum="05AC2DB029FC055E" modified="2023-09-13" version="1">MKVISLLLVAALALTATPISEAKVGTVEPLSCPCGGKRDPWHPACCPSEESVSPKDAKAAASSSTVEPLNCPCGGKRDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYI8</accession>
    <name>A0A9P6SYI8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_001111</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001249">
        <property type="protein sequence ID" value="KAG0010881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYI8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="36"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="114"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="38"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="61"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="73"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0010881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="170" mass="18507" checksum="6436F388C7F8389A" modified="2023-09-13" version="1">MCQRTICRDCGKFTWTGLSLDEICSCDDDRDSEHPWATLTNESSNNASRGVISTDSTPYTSQSLSGSLSGSQAFTSTTSYPLPQTTSTTAARTDPAGHCIDPSPIEYKLSKISSESAEAAMSRKAQQAAALEELRKIKEKKDRELKGANERALNKLLQGLSGTFRDFGER</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYJ9</accession>
    <name>A0A9P6SYJ9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Anaphase-promoting complex subunit 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ANAPC1</name>
        <name evidence="11" type="ORF">BGZ80_000290</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the APC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001056">
        <property type="protein sequence ID" value="KAG0011980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060090">
        <property type="term" value="F:molecular adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007091">
        <property type="term" value="P:metaphase/anaphase transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070979">
        <property type="term" value="P:protein K11-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024990">
        <property type="entry name" value="Apc1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048971">
        <property type="entry name" value="Apc1_3rd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041221">
        <property type="entry name" value="APC1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046794">
        <property type="entry name" value="Apc1_MidN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049255">
        <property type="entry name" value="Apc1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002015">
        <property type="entry name" value="Proteasome/cyclosome_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12827:SF3">
        <property type="entry name" value="ANAPHASE-PROMOTING COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12827">
        <property type="entry name" value="MEIOTIC CHECKPOINT REGULATOR TSG24 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12859">
        <property type="entry name" value="ANAPC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21282">
        <property type="entry name" value="APC1_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18122">
        <property type="entry name" value="APC1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20518">
        <property type="entry name" value="Apc1_MidN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01851">
        <property type="entry name" value="PC_rep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0498">Mitosis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Anaphase-promoting complex subunit 1 N-terminal" evidence="7">
        <location>
            <begin position="90"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="Anaphase-promoting complex subunit 1 middle" evidence="9">
        <location>
            <begin position="806"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="domain" description="Anaphase-promoting complex subunit 1 beta-sandwich" evidence="10">
        <location>
            <begin position="1565"/>
            <end position="1620"/>
        </location>
    </feature>
    <feature type="domain" description="Anaphase-promoting complex subunit 1 C-terminal" evidence="8">
        <location>
            <begin position="1719"/>
            <end position="1929"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="142"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="480"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1908"/>
            <end position="1930"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="144"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="480"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1918"/>
            <end position="1930"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1996"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF18122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF20518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF21282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0011980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1996" mass="223198" checksum="C90E1294A9DA7CBF" modified="2023-09-13" version="1" fragment="single">MEITILGEYRPFGDAEEIIDRVSHVGEPFLPPKPYHFGEPDKDDSYTANPLSNSSLPRYELYPPTHDGVINETRESSTIGSSHANINRSKSQRGYDVEVTVKGSKVTWTQGGILRKTLDFSSENEVIHQTLFAWFIVNNPTQRTTDRERDREQEREEDFEVGQLHTTERPRADWQSRQQALVVILKDTARIYFPSGESYSVHLPFGIHKVWAMDLGLFMERKPDLDEEVPKETPEEFGGTELPMPRFYTIMDPFNEVLMVTLYRLPKSSKQTTSGKPAPREEAPRIRHMNGVVGDIFNTCVFLSCLDSSDRTVVTFDLVSKRHRVWRYASSMLTALPFSRIHSQSGPSSDTVMEVDNDADLQMRTDTYLFEIESNIQGASHDSMIFSAHAFDGSTVIGVLDREAEKLSCYQIIADQIVVQLWTKPALSAVAVEATRKQLRDILILSHKGELQLWTGFSAEFVPCQADIEPMFLKSKGVKGKAKTRAKKQSSKTPGLDSASTDNHDVMSKEPPYIIEIRDAVENRVSFVLSDNTVLRMQLDFLIRSSLVQECIDAISYALPTDALWDFKHRFLQLHFENVSREAEPPADEWCDFTTTLLSYCDPSFTPPVMSSPKMQTRTLSGLTKKPVNNDSSWDYFLDSEIHRLMKNHPSFRNESLALPISNTNPYTEMIMQAQKLATLHFRGPATRQSLRLDWFYTYILVALHLVYEDRDLNLVTRKEGDMTPLLTLMAHIVGWKTWVDAYARRDFARLKDIELPASLAALRDSEQSPFPVLNSTPCDLTRKVTLFFTSLMASDDGDQSAVRAIVDEAFTNNQLDQLPFGVSVPLREALWKCRRDPSPDLNSDALSFIGRNDLAELASKMSSGYYMKPPSQDKTEPTKRQDVHSLCDGVVHQEGDGELETTGAEITESDITDLRFGADMRVAETQKMLRSSVVLKIKPEEAPDLNEEDLRAMHQELLCKMAIRTLALPVGRGILTFGTATPILNQKCPIPPINLAVKLLPSYGTMEPDLIALGGEQVLNWPDFHNGVAAGLRISSNSKDVTSSWIIYNRPEALNSSHAGFLLALGLTGHLRALARSHVWRYLSFKHELTSTGLLLGLACAHRGTMNTAITRVLSVHMPALLPQHGSELNLSPLTQVACVLGIGLIYMETSHRRMAEVMLSEIGSTAGDSVDSLNSLQECHSVAAGFGLGFITLAQGNKSVGLRDMKIVDVLVSYMPGTTDKNHGAKSLAGPTQGEEYGSNRRQAGIDMTSAGATVAMGLMYLKTNSKPIAAKLSVPETQFLLDYVTPDLLMLRVICKAIVLWDSIVPTKAWVLSQVPDYLKNIKTGGPPATETGPQSYYSILAGACFAMGLRFAGSGNEAAYECILKHLDMFIDLGRANRDGSYEDSITKSTIRTCLDVTAMSVAMVVAGSGRIDFLRRLRKLARRTKGDTTYGSHLSYHMALGLLFLGGGGYTLGTSNRCVAALLCSLYPRLPSDPMDNRSHLQAFRHLWVLAAEPRCLVTRDASTGACCPVPVRVHLKAVYCQTQVQMGLGVKNSVDHHQDIIRPSQLTGLNSNVSQDTATTLFSSSRLDMMTPCLLPELSLISKIEILGPRYWPITIDLSDKNEDYGSIWKILKTRSISVMRHIGHLSYTEDPLGMRGILARPFPKVLTSEELGETVDNGSARSRKQEKLQRLANARREWYIRGGQSSRGLEAGQLDIPSYQDFDQSSASYGEDFCLTFLQDPHVASFASHLCRVKSGDREDGLGVGKDELRAAYFTNVLYECLTIDKVEVLGVHVWLYDIANRLENLDEISRRTLWELRILTNYYDTLFRRRLLEKGEELPTEIRTKERDEDTAIEPDTVLALSPHVMEDDGSETLIKVSRVTELVSRITKRVEQAMDEHRLDPEQQEWSMDSIAHRYFKTGSMPTERKNQNKNLSSANLTTGDSTQLKSKTNWFKVWLELNEVPGPDAIMSIKTALENTRSTWGNYVDAQEAQIDSEGGSEDFKTVANE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T013</accession>
    <name>A0A9P6T013_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_010877</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000805">
        <property type="protein sequence ID" value="KAG0013757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T013"/>
    <dbReference type="OrthoDB" id="10001928at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43503">
        <property type="entry name" value="MCG48959-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43503:SF2">
        <property type="entry name" value="NEGATIVE REGULATOR OF SPORULATION MDS3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="BTB" evidence="4">
        <location>
            <begin position="610"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="117"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="202"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="317"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="377"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="754"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="831"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1002"/>
            <end position="1074"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="15"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="122"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="202"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="218"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="321"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="331"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="762"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="801"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="854"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="881"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1031"/>
            <end position="1046"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="1047"/>
            <end position="1058"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0013757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1074" mass="117487" checksum="38B2FA31036C956F" modified="2023-09-13" version="1">MSFATTVPSIPLNEYTASPNNGPSISRTNTYTLRNEHQFQHEEISAQPTRTSTKALAITSCASAGSPPPPLIGSAIVLANDSAMHCFGGRLEDRTLTNCHYVLDLETSIWETIHAAPLPPESTDTTESETATAGDTNDSSTTGRSSTEKPTNISLSLATDPVDTDSGPISGVPSIHPPPRYFHTLNAFGTFLILFGGMGRVQDPDDKEKDKDEDESKQQTGDNDTGNQGTLGALNDLWVFDTVSQQWQQKHPQVNSHSPRPRWAHMATIMDHYLVVIGGTDTFKVYVEDACVLDLQTWEWVATIPSIGQCGSYRTVAATGPSKQSSTSTEPAVSSFPSASASSPQTSSNLARPLTDSGPVDTMASISMVLSGRISAPSSAASSKDDDTSDTSSNKRKHSGRLLSGELTPSFRTGKDVPSIYLYSNYNFTNLHRDFKVITPHYTHPTVAAADTTLTTSAPVAPPSFSLIEKSQALNMMGPELPPGLRFPQGHVYQNQLILTGTLIVPNMAPTLAIYSFNLTLYKWERLDTDGLLETGSWNRTLLHPATGTLLVFGNQQTDPRKDYASRLQHHNHFMLIDLQAYGLYDRPIPSMPQVAQELGQELLSNPSLCDMHISSVDGNLFGANSTLLAARWPEFSSLLLSPPYVTPLILILPVPDEVVPLFLQYLYTGALPQDITPGIADYLLILARKYELNGLYALTMDILHQTVHLRPVRIYSSALLAGEMGLQARAVGLAMPKLPARVGQITASAIEGKELPPLPSPASTVVSSSNSTGLGRSYSGRVPPPPPTGPYVKTHRRELSNQSRESISTDGGLTAEGLLQQYGQRQLPSVIPEDDIDPRRQPPLKSPQLLSPTSLGRASDYSSPLNSPGMAQGYGGFSQSGFPSPLSPTSSFSSQQISLRGFGYDDYTPDERTLQARRRLQMQMQQEPDIPLSQHQYHQDQLLQQQQQMRDQEAVVMEQHRLQHQRYLQKQQQIQAHQLQVEQPTPAAVLDELDYHFGGGIKQPSAFRIRSPNESMRAETSSSHSGSSSQKEKEKEKEKEKEKDKKKDKKLLSKMKPPKPTLSGAELMKSAGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0C6</accession>
    <name>A0A9P6T0C6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cytochrome b5 heme-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_010438</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000726">
        <property type="protein sequence ID" value="KAG0014438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0C6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004128">
        <property type="term" value="F:cytochrome-b5 reductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.120.10:FF:000001">
        <property type="entry name" value="Cytochrome b5 reductase 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018506">
        <property type="entry name" value="Cyt_B5_heme-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051872">
        <property type="entry name" value="Cytochrome_b5/Flavoprotein_Rdt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46237:SF1">
        <property type="entry name" value="CYTOCHROME B5 REDUCTASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46237">
        <property type="entry name" value="CYTOCHROME B5 REDUCTASE 4 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00191">
        <property type="entry name" value="CYTOCHROME_B5_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0349">Heme</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="5">
        <location>
            <begin position="602"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="263"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="446"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="491"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="491"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="506"/>
            <end position="516"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0014438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="689" mass="78510" checksum="52F6FBC30DEE1ED9" modified="2023-09-13" version="1">MNFAKDSIAGSLPPEVIFYFGQYLQGSSLVSSLQVCRHWNQILSPYVWKSISKMQWHHPYFPLGTIFEDIYSDDGTNAVCPEIQLLQHLEWWSDLTISHKIDEAVELTEEFPFSCLELRHLEKLDLTIWEHDSDGLPPEKIYPLFQKLKELKLYGTWINFEDKDLSSLRHSPSSCFFQQNDASMTLNLRVPEGPSIRSSLLPLLNFPNLEKLKLYNDSSSRLRSRAWRELPRVIPALKKLRSLAICVFSLDHIKFLCAPSGYRQRHDDKDLPPSTTKDSNDSEQCLALPLLEDLEIDPYGFLEDCLEEDYKKYGECLFNILKTRHLLKRFIAEGRFLQPEDIFARPKMEEQDGWACKDLETLLIGFYLDLRSKVDHRERSKIVYRQIGELPKLRRLAIQGSERVLKFLEMMPDLEVLHIERDSREDHYKILPWLEEGYVYPAEADSANDVESNDQEHATETQPSNPYSAASNANNKRIIVQSPFPATLTVPSVSLNSLQPPTVTTEDSDQDTDNDSEVNLATPYLALPGNSSTPMMTLSTAEAPDEATPSFPAMNGPQRLAACSTDPKSKRRIKFALAPGHSPLDWARLTNSGANLRGVSTIGRFTLSDIKAHNKADDAWTVLNGKVYNITPYLPFHPGGEKELLRCAGRDGTKLFNLTHKWVNYEFMLKECQVGYLVSEAPSSYQLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0D6</accession>
    <name>A0A9P6T0D6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_010409</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000720">
        <property type="protein sequence ID" value="KAG0014506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0D6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051615">
        <property type="entry name" value="Transcr_Regulatory_Elem"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313:SF81">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="8">
        <location>
            <begin position="409"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="77"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="192"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="777"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="986"/>
            <end position="1081"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1108"/>
            <end position="1204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="102"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="119"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="155"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="194"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="840"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="990"/>
            <end position="1081"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1151"/>
            <end position="1162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0014506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1204" mass="132632" checksum="57F7CA8EC82FD24F" modified="2023-09-13" version="1">MSKEEHKERQRVTKGLYLDPTKKRGPPKGAGRYINAIEDRLHRMEAIVGGLVREDDPLFHADEGNLRALLSNAASLRNPSSRNSYDGSDMHHHHNQPSYIRPDLDNQNHPHPLRDYNSLLQQQQQQQQQPQPLLMQYPQQQQSHPSYPSRMMDIQYSQSPDLGSQNHPDGIHHGVDSKRPCTLTREVIRDGSFHSFNSPSPALSSEHSIGDLGDSPTENLPRLGVSTPPISEVDDLEDDMGHLSIDQRGHERYVGKSSPMFYSGRPYSGAGLDLNREKEPQTPEALRFLDNPDLPSPEVMTRLLNLHFTYVHPFAPVFVWSKFLRRLQERDYTPSFLFLLNSIFALASKFSDDISLRKDPTNQDTMGFRFADKAKEILDTLYDSPDLNCVGALNLLSFQQMGTGNGYKAWMYVGISIRMAQHLGLHRDCLKITPTMPALEREERNRIWWTCVLADRIISTSFGRPQGINEYDVDARYPEGVDDEGTQLEYRLEGATSTLTGPSLCSEKNFVYLASLMRILGRVMVSLYSPISKASSKSKTSMTNPAPLEQLDKELTDWLLTLPPHLQFRSVQQEPGTFVCMLHMNFYAVLILLHRPYSHQSNHNTLNDPSISMSICTSAANNAIEMASNLMRSLDEKRGTSRLKCLLQNSVFILFTAGLVHITNCTSTDPALAASAKLRTIEVLRCLSIVEDVWLSASLIIENIKNLLKARNIELPYSSEVFKSLPIGSVEDMKRRLGLTNSQSDAPAAAAVVPKEQSFAYGVDQIMGYYQANQADQATGTKHAEPMGRNSRHFSPSPYFSPVSGQHHYHQSQGSMKSHPGLTQGHSPLPRRPRQTKTLSPSPSVSSISAASIPVQSPVTPTFFPNSQDGGVGGFQFFNNNDTNSSGGFNVNVNGNADTQTDPFATPGSATLAGNSIQQQQQQPQPQQQQIASIESQQTLSAYQNPFSASLWGLPTSLDNDEWMLYMQNNGGNTEQSLDLSVNVQSGAFNNNSNANSGNNSNNSNSNSNNNTSSNNNNNATTTSNSNNINNSSNNNNNNNNNNNNNNNTSSGSNNNNNNNNNNTSSSSNNNNNIVNDGSINSINSGVKPDVSMYSPLSGVDLEQNNINNSLTVNGTSNNNPSNGGGNRMHPLAQSMTRGELLSSGDPNDPINANHSSSSVSITGADAPRDHPSPAGQPSTSDQQQQQQTPEFYFMNGNLSMGST</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0Y1</accession>
    <name>A0A9P6T0Y1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">D-arabinono-1,4-lactone oxidase</fullName>
            <ecNumber evidence="2">1.1.3.37</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">L-galactono-gamma-lactone oxidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_008761</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; D-erythroascorbate biosynthesis; dehydro-D-arabinono-1,4-lactone from D-arabinose: step 2/2.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.3.37" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010000487">
        <property type="protein sequence ID" value="KAG0016933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0Y1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003885">
        <property type="term" value="F:D-arabinono-1,4-lactone oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2520">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007173">
        <property type="entry name" value="ALO_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010031">
        <property type="entry name" value="FAD_lactone_oxidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43762:SF1">
        <property type="entry name" value="D-ARABINONO-1,4-LACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43762">
        <property type="entry name" value="L-GULONOLACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04030">
        <property type="entry name" value="ALO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000136">
        <property type="entry name" value="LGO_GLO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="6">
        <location>
            <begin position="42"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="18"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00033418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0016933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="505" mass="57260" checksum="0BF572C1057F672C" modified="2023-09-13" version="1">MTQKERFRLLPDFIGKIKSGSQSESKSEPAKKYSFKNWSGNQRSNPAKIFNPTTLEDLVDIVRQAKANNKVVRCVSGGYSLSGSSVVNDEGYLVVMRKMNKIRKPVHVSGNVWTVEFETGVSVGKLDNYLRRHDPPLTLTSNVAVTSLRYGGVITLGCHGASTSSGTVADHLHEVKIVDSTGTLNTFSREKDPNEFSAAAINLGLLGVVYTYTLQVEPMYTLLMRDTSPPIDGFIECPKIGGARFKTMTLGNDQVQIFYNPFLKSKPGCEKLWIKEWTRTDLPVTECRAMSKLKRRIEACGLTMCNVMYKMMLKVPNAMSPMAKMLYKFMSMNKEEVLQASEAMHYLGGVEKMPFRCCEVAFKMDENFENVSKALKFVIDQIRECAKKNTYPVNIMLEMRFIKSSQLLMANVHDDDPEAFFCTLELISIAGTEGYDEFMGKIAKYWMDNFNAQPHWAKDWESLPEVYPHIRKHAGARFEKFDAIRRTYDPEDMFMNKTFAGVFGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T122</accession>
    <name>A0A9P6T122_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008387</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000452">
        <property type="protein sequence ID" value="KAG0017346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T122"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0017346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="191" mass="21320" checksum="733231D7309974EB" modified="2023-09-13" version="1" fragment="single">MSMSRADWALSTFDASFPAFVKKFEYEDQDLASKHYSDLLRNKKLRATFREKLQANFNAWKIQSEDLFWQKRMNLRNDRKGIAKAEGALIAEASSNVESTIIQSNKIAKSSSILSGTTPLVSNAKPRAAAHDEVHNAEGQESFDLESEHQGEESESESESAAGDIQEDGFTTQESSNILANIARSQHPFCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T180</accession>
    <name>A0A9P6T180_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Carboxypeptidase</fullName>
            <ecNumber evidence="4">3.4.16.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">KEX1_3</name>
        <name evidence="5" type="ORF">BGZ80_007991</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the peptidase S10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.-" evidence="4"/>
    <dbReference type="EMBL" id="JAAAID010000420">
        <property type="protein sequence ID" value="KAG0017722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T180"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018202">
        <property type="entry name" value="Ser_caboxypep_ser_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802:SF479">
        <property type="entry name" value="CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00724">
        <property type="entry name" value="CRBOXYPTASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00131">
        <property type="entry name" value="CARBOXYPEPT_SER_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040541330" description="Carboxypeptidase" evidence="4">
        <location>
            <begin position="26"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0017722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="473" mass="53545" checksum="78611C63E9123C90" modified="2023-09-13" version="1">MSILRLTTAIVMALLFTPLSIPASAKPHQYASSHPHDHAAKYRIDTAKLPGLDKELTALPQWSGDIPVGNNNTLFFWYTQAKNLKSDNLIFWHNGGPGCSSMEGLFEEIGPYRSKDQGRTWHMNPYSWHNFGHVVYIDQPFGTGFSTNNVTVPNEDFIGNTMVNFYLNFFKAFPEMKSKDMYIAGESYAGRYIPYMAKHVLDHNDKHKNELIRLQGIVLGDAYVDTDINNNFINYLPFVKEHKWIYANNETWLTEAEQLVEQAKKLPGCGNAKSDSEVSDACVALENQFYTCTNGGNPMYYDPYNINIKDCLQAQIDDSAAQASWEYYLNLAEVQDQIHISAPTHYVNCVNINSGIYALDPSIVTKYFIGSLIDRGLKVTMYSGLLDSVVPHTLTEAVIRQMTWKGHKGFAHSKMTKATMKPIIAGHPAKQRGRYHSERGLTYVVVDNSGHMMPRDDPVTAFWMMDKIVINKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1C8</accession>
    <name>A0A9P6T1C8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DAGKc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_008011</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000422">
        <property type="protein sequence ID" value="KAG0017696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1C8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001727">
        <property type="term" value="F:lipid kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046512">
        <property type="term" value="P:sphingosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001206">
        <property type="entry name" value="Diacylglycerol_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050187">
        <property type="entry name" value="Lipid_Phosphate_FormReg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045540">
        <property type="entry name" value="YegS/DAGK_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12358:SF108">
        <property type="entry name" value="DAGKC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12358">
        <property type="entry name" value="SPHINGOSINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00781">
        <property type="entry name" value="DAGK_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19279">
        <property type="entry name" value="YegS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00046">
        <property type="entry name" value="DAGKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="NAD kinase/diacylglycerol kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50146">
        <property type="entry name" value="DAGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAGKc" evidence="5">
        <location>
            <begin position="6"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0017696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="377" mass="41155" checksum="F64CF008F7B14429" modified="2023-09-13" version="1">MGILPTSNFPLLVVLNPHSGKKQGREVWDSIVQPALNKAEKPFKLIESNAQGHAQSYFFDNIKPILTDLIQSLSAVNEPVDNASAIIRPSSVTLQIMVLGGDGTVHEIVNGILRGVEGTGYVSDEFRPKVEFSIIPTGTGNAISTSLGVTSVQDALDRFLVGNATPLRLMSVSTRAESGWKVHVYTVVVNSYGLHCATVYDSEEFRHLGNERFLHAAMKNVENLKQYEGQLVFYGPVQSYDRSTGSLTPVSSADSNGPTISLPGPFTYLLITKQASLEPGFTPTPFAKTSDEWMDVLAVQNVGKAEIMEMFGSTSTGKHVEQKTIEYFKTKTVELETPTQGRLCVDGEFLTIEGGPEGRVRFEVISDENIQIFGVYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1I7</accession>
    <name>A0A9P6T1I7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 12">Mannose-6-phosphate isomerase</fullName>
            <ecNumber evidence="5 12">5.3.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">PMI1</name>
        <name evidence="18" type="ORF">BGZ80_007246</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>D-mannose 6-phosphate = D-fructose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:12356"/>
            <dbReference type="ChEBI" id="CHEBI:58735"/>
            <dbReference type="ChEBI" id="CHEBI:61527"/>
            <dbReference type="EC" id="5.3.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11 12">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="11 12">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 14">Nucleotide-sugar biosynthesis; GDP-alpha-D-mannose biosynthesis; alpha-D-mannose 1-phosphate from D-fructose 6-phosphate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the mannose-6-phosphate isomerase type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.8" evidence="5 12"/>
    <dbReference type="EMBL" id="JAAAID010000368">
        <property type="protein sequence ID" value="KAG0018367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1I7"/>
    <dbReference type="OrthoDB" id="6605218at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004476">
        <property type="term" value="F:mannose-6-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009298">
        <property type="term" value="P:GDP-mannose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07011">
        <property type="entry name" value="cupin_PMI_type_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.441.10">
        <property type="entry name" value="Phosphomannose Isomerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001250">
        <property type="entry name" value="Man6P_Isoase-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016305">
        <property type="entry name" value="Mannose-6-P_Isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018050">
        <property type="entry name" value="Pmannose_isomerase-type1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046456">
        <property type="entry name" value="PMI_typeI_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046457">
        <property type="entry name" value="PMI_typeI_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046458">
        <property type="entry name" value="PMI_typeI_hel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00218">
        <property type="entry name" value="manA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10309">
        <property type="entry name" value="MANNOSE-6-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10309:SF0">
        <property type="entry name" value="MANNOSE-6-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01238">
        <property type="entry name" value="PMI_typeI_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20511">
        <property type="entry name" value="PMI_typeI_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20512">
        <property type="entry name" value="PMI_typeI_hel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001480">
        <property type="entry name" value="Mannose-6-phosphate_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00714">
        <property type="entry name" value="MAN6PISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00965">
        <property type="entry name" value="PMI_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00966">
        <property type="entry name" value="PMI_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12 18" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11 12" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Phosphomannose isomerase type I catalytic" evidence="16">
        <location>
            <begin position="8"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphomannose isomerase type I helical insertion" evidence="17">
        <location>
            <begin position="168"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphomannose isomerase type I C-terminal" evidence="15">
        <location>
            <begin position="339"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="299"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="280"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001480-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR001480-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU004248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF01238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF20511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF20512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAG0018367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="442" mass="49050" checksum="FAB98937B6846FCE" modified="2023-09-13" version="1">MTASQPAVFRLDCKAQSYDWGKIGSSSKVAKFASSSPSFTIDDSRPYAELWMGTHPSGPSSVYQSDKTLESVLKANPKLSSPYFAERYQGRLPFLFKVLSINKALSIQAHPDKHLAQKLFKERPDIYKDDNHKPEMAIALTEFEALCGFRPLPEISTALDQWPEFRSLVGDKEATDFQDAVVRSQSIDGIRGVKEGRQALKILYTTVMTAEPSKVKFELDRLVARLGATGSEYPLHSIEELLLRTHAQFPGDVGLFSMFFLNYVVLKPGQAIFLAANEPHAYLSGDCVECMAESDNVIRAGLTPKFKDVEVLTQMLTYQSKSSTDQLLSGVLCTPTGHSLMYDPPIEEFSVILTTLDHPKEKERLRGAEGPSIVIVTKGKGVIRSEKHTESDSDVVEEIVETGNVFFVGANTPFSIEALSEEGVTIYTAFSVKPDKKDHFHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1S6</accession>
    <name>A0A9P6T1S6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007002</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000351">
        <property type="protein sequence ID" value="KAG0018588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1S6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="177"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0018588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="328" mass="35877" checksum="D6E8676D7E2D29B5" modified="2023-09-13" version="1">MPPATITESARRQAQGLSTNHNFDRTSYVSRSMLISPMPTYPNSRSTPNTSPTTNYSSSPTSFGVSSTAVSSLGPNTTKICGAVLGSMVALSLLCCICVFRRRLLNNQFVHSVQAQKHLDFESPGGTDMKRYETLDKARIVVVIGDIGTENKKGACFREDELPKRTSMRVGDKGPTSSVAPSSSLSLSSSSSVLWLFFKSTRIFKAIDGHKKHDVVPPTLEETSTRFDPSRYPGAAPGYSTFKSMPICVLTPPPTLQQKRSTSDVISNNRPKIVKDTKDVVNDSSNKKSSSAGENVKDIWERTGGLILKGRNEQRSKNHVSQYFKAQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T281</accession>
    <name>A0A9P6T281_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NodB homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005703</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000280">
        <property type="protein sequence ID" value="KAG0019525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T281"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040452298" description="NodB homology domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0019525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="517" mass="55013" checksum="7E2B36B32096EB99" modified="2023-09-13" version="1" fragment="single">MKLLTLITAASCLISPLANAAVSIPDITTLKGPLTNTPVPSSGDGTVTDPSNTTFGTGTASRLALYVPGNVYSDYPGWLPLYKALVFQGIPVTVTKNIKVAKNHPTVIAYQALQSKYMGTTDSSTWSKYVSGGHTLIAIGMTSSDTLIASTFGVTPDTNTNTNARQAIALNAPMASVPASSVNSQFDLTNTNDAQIPLWRQDLGTGFPTIGYTVSAGSGTFALGSYLTNTGANDTKQAITIKSTSNGGHAIAIGFDVGAYVGESTGGRTNGIPRSYDAQYDPGYDNIFRMIKTLYSTSTPTGLVTSWPVPGNKGVHFSWTYDIDAQDSYELALVVAQDLQSRGIKGTINWQAKLVKDAYDVASLNISLVEALGNMELSSHSVSHSPNLASFPIGTGKEIWDGTKYQEDNYFPFIGQCINTNGTWATSVPGASSCDTPNANLYFYTLGGSIFGETRVSKYILESISIVNATVRSFRTGHLLYPDALPQVLAAAGYKYSSSSAANDRNSHMPYQTFYNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2B6</accession>
    <name>A0A9P6T2B6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cytochrome b-c1 complex subunit 2, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">QCR2</name>
        <name evidence="13" type="ORF">BGZ80_005740</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the peptidase M16 family. UQCRC2/QCR2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000282">
        <property type="protein sequence ID" value="KAG0019499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2B6"/>
    <dbReference type="OrthoDB" id="6369905at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000021">
        <property type="entry name" value="Cytochrome b-c1 complex subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000039">
        <property type="entry name" value="Ubiquinol-cytochrome c reductase core subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.830.10">
        <property type="entry name" value="Metalloenzyme, LuxS/M16 peptidase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050361">
        <property type="entry name" value="MPP/UQCRC_Complex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11851:SF209">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11851">
        <property type="entry name" value="METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="LuxS/MPP-like metallohydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Peptidase M16 N-terminal" evidence="11">
        <location>
            <begin position="38"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M16 C-terminal" evidence="12">
        <location>
            <begin position="183"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00040751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0019499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="436" mass="45586" checksum="51834071E85EC1F2" modified="2023-09-13" version="1">MLSISSARKTMNLVPTILKAGYATAITKTSNGVKVAALDESSPAASVSLVINAGARFEPKDKAGLSHFVKNFGFKNNGKRSAFRITRETELVGGVLSSDLGRETVTFTAECLKEDVPYFVEIFGDLVSQTKFNEHEFHAVANEVAAECTVAEASPEVTVIEALHNAAFRNGLGNPIYAAPYSDITTEDLRKFAVDNFVGNKISLVATGISEAELKSLADSAFSNVASGSASVTEATKYYGGDVRVAHNSPVGHVAVAFQGAAAGTPDFYTAQVLRSLLGGDRFVKWSTSGVSPLAAAASKIGHGAQISAFNFGYSDAGLFGVYAQADHESVTEAAKAAVASLKAASKAVSAEEFKRALAQAKFETASRFETRASTTEILAAQAIQGQKVDASESLAALDKVQAGDVSKLAAKLLSSKPTTVVLGKTSELPYGDALF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2Q8</accession>
    <name>A0A9P6T2Q8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">AIG1-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_003947</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000208">
        <property type="protein sequence ID" value="KAG0020576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2Q8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00257">
        <property type="entry name" value="beta-trefoil_FSCN-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008999">
        <property type="entry name" value="Actin-crosslinking"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006703">
        <property type="entry name" value="G_AIG1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04548">
        <property type="entry name" value="AIG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50405">
        <property type="entry name" value="Actin-crosslinking proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="115"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="AIG1-type G" evidence="4">
        <location>
            <begin position="316"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="246"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="250"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="271"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="286"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0020576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="536" mass="59206" checksum="4D518A4277E24300" modified="2023-09-13" version="1" fragment="single">RRGMLPDQPSQLLPIDGLYHIKSYDGRYLTRKWSGVVELHRKEQDEDETSWEVRKTVGLRGKTKFAFYIKGHYLLCMQTGWILANSKECDSWEQWTITTEYNEEPLNGPSGRRSAFYVCAGGFILIGGVVAATIYIATSDGKGGTSNTQKYRSEPKPKKKIKAPAVQQDCEEKAAPAACCDNNENYGDEKADTDEKAGDDGTLATIGKSIITVAKAAEEHGPQIVKAIEATAAVVEAGKKSLGIGVREESEYEEEYEEESEEPAPGEDEASTNAPARSLAESKSSTRAMAETRAPTEAPAPTIAGSRPQKRSSTKKIILVGKSGVGKSTLCSMLLQGDLYPQNRREISNGATSVADCQVLEGREWTVCDTPGLGETYEGATDTAIKPIVQVLQEKQLAFHYIAYVIKQGRLSVKDHAEHFKLFKSTFKGAERNFVLIITHCEDREWIVENQEDIISIFGDILILFCDLPFSPKNAERGKKERLHHFSEFEHDILSLDHDAILPWISCGAVPPVEETIASLSINSERSRGHENKTTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T398</accession>
    <name>A0A9P6T398_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cyclin-dependent protein kinase complex component</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003793</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000202">
        <property type="protein sequence ID" value="KAG0020679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T398"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000307">
        <property type="term" value="C:cyclin-dependent protein kinase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013922">
        <property type="entry name" value="Cyclin_PHO80-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615:SF94">
        <property type="entry name" value="PHO85 CYCLIN-6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08613">
        <property type="entry name" value="Cyclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="224"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="311"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="262"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="324"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0020679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="358" mass="39109" checksum="77BFA629DBF4A896" modified="2023-09-13" version="1">MVHKRGRDDENLDPSMPKSNLSEHHHRGQTDSQPQNDADLYRALKKTKLEPISSTSNIMNAAVVAAAASMASSEHTQHQSTLTEMTKETGTIDVQSMPGGSTPAPTPKLAVASNGFRINSFNIHRLLITCIMVAAKFTSDHFYSNARYAKVGGLSLLELNQLELEFLFTTRFELNVKVEELQKVGNSLLRFKNRELASQQTRPQQQYRSTQLDLQRTSLHGNTINTTSCVSSQDSQGLQQKKGRFSIPTPTSPRNGPMSDRTASTSSSSLPSISSSLSSSPSPSSSSSSLAVTSTAATVSSPITTTVIVVSGDRVQHPQLLSPPEEKHRWAESEVQVTEEHIDQTQERNRSSPQYSSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3A3</accession>
    <name>A0A9P6T3A3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Mitochondrial carrier</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BGZ80_003767</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000201">
        <property type="protein sequence ID" value="KAG0020707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3A3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45667">
        <property type="entry name" value="S-ADENOSYLMETHIONINE MITOCHONDRIAL CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="224"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="267"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="332"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="28"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="118"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="272"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0020707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="359" mass="38926" checksum="45FE950EACD85D5B" modified="2023-09-13" version="1">MARSTSKTAESRELSVDPNSTKHRSTNNGALNNLLASSIAAFVSRLCTHPLDTLKTRVQASNKPLPLLPTFLDLVRNGGLYRGLPVALTLSAPGLSVYLTAYDLSKDKFSYFKYLGKDSVLNHLASAATAEVLSGLFWTPMEVLKSKQQVENVTSVSPIAASKSRNLAAVGATPKSASSFSTTTATATPVTAKTPLPATRMPISTAELAKMIYQQEGLIGFYRGYFITLGVFVPYSMIYFATYEQLKEMARQRRGRNSSDNIKSDDALPFFTVALCAAVSTGIAGGVSNIVDVVKTRWQVSVLATTEENSSTRRIVSNMFRRGGLASFTQGMAARVLWMIPSVTISMSVYEWLKAHGFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3U0</accession>
    <name>A0A9P6T3U0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Alanine--tRNA ligase</fullName>
            <ecNumber evidence="15">6.1.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Alanyl-tRNA synthetase</fullName>
            <shortName evidence="15">AlaRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15 17" type="primary">ALA1</name>
        <name evidence="17" type="ORF">BGZ80_010899</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14 15">Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 15">
            <text>tRNA(Ala) + L-alanine + ATP = L-alanyl-tRNA(Ala) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:12540"/>
            <dbReference type="Rhea" id="RHEA-COMP:9657"/>
            <dbReference type="Rhea" id="RHEA-COMP:9923"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78497"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="15">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="15">Mitochondrion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="15">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="15">Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.7" evidence="15"/>
    <dbReference type="EMBL" id="JAAAID010000081">
        <property type="protein sequence ID" value="KAG0022903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3U0"/>
    <dbReference type="OrthoDB" id="2423964at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004813">
        <property type="term" value="F:alanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070143">
        <property type="term" value="P:mitochondrial alanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00673">
        <property type="entry name" value="AlaRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.130:FF:000004">
        <property type="entry name" value="Alanine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.310.40:FF:000003">
        <property type="entry name" value="Alanine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000011">
        <property type="entry name" value="Alanine--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.980.10:FF:000004">
        <property type="entry name" value="Alanine--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.980.10">
        <property type="entry name" value="Threonyl-trna Synthetase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00036_B">
        <property type="entry name" value="Ala_tRNA_synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002318">
        <property type="entry name" value="Ala-tRNA-lgiase_IIc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018162">
        <property type="entry name" value="Ala-tRNA-ligase_IIc_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018165">
        <property type="entry name" value="Ala-tRNA-synth_IIc_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018164">
        <property type="entry name" value="Ala-tRNA-synth_IIc_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050058">
        <property type="entry name" value="Ala-tRNA_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059090">
        <property type="entry name" value="ALA1_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023033">
        <property type="entry name" value="Ala_tRNA_ligase_euk/bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003156">
        <property type="entry name" value="DHHA1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00344">
        <property type="entry name" value="alaS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11777:SF9">
        <property type="entry name" value="ALANINE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11777">
        <property type="entry name" value="ALANYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26023">
        <property type="entry name" value="ALA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02272">
        <property type="entry name" value="DHHA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01411">
        <property type="entry name" value="tRNA-synt_2c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07973">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00980">
        <property type="entry name" value="TRNASYNTHALA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101353">
        <property type="entry name" value="Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="ThrRS/AlaRS common domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50860">
        <property type="entry name" value="AA_TRNA_LIGASE_II_ALA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 15" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="8 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 15" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 15 17" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 15" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10 15" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 15" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 15" id="KW-0820">tRNA-binding</keyword>
    <keyword evidence="7 15" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Alanyl-transfer RNA synthetases family profile" evidence="16">
        <location>
            <begin position="8"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="605"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="609"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="724"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="728"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00055137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0022903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="963" mass="107124" checksum="65E36C662FDBBD0E" modified="2023-09-13" version="1">MSFRPDYWTAAKVRETFISYFRDSYAHTFVPSSSTIPHDDPTLLFANAGMNQFKPIFLGTIDPNTEFGKLTRSVNSQKCIRAGGKHNDLEDVGKDTYHHTYFEMLGNWSFGDYFKKEAIDMGWKLLTEVYGLPKDRLYVTYFGGDEKQGLSPDLEAKELWLKVGVPENRILPGSAKDNFWEMGEQGPCGPCSEIHYDRIGGRDVAHLVNEDDPNVIEVWNLVFMSFNREADGSLRPLPNKHIDTGMGFERLVSILQDKSSNYDTDVFQPIFRAIQNVTGARPYTGLLGAEDKDGIDMAYRVIADHVRTLTFSISDGGVPSNEGRGYVLRRILRRGSRYARRKFGVQIGTFFSSLVDTVVAEFGDAFPEIRTRIDDVKEILNEEEEAFSRTLDRGERLFDGYLQKALESKTTHLSGADVWRLYDTYGFPVDLTRLMAEENGVSVDEEEFSKQQEAAKALSRAGKGSGAGAGEVVAFDVHDIAAVDAKGSVPKTDDSFKYQSGNINAHIKLIYRNHEFPQDTSSIEEQKSFGILLDRTNMYAEQGGQEYDTGSITVDGKAEFVVENVQVYGGYVLHTGYLKYGTLQVGDEVVVQFDELRRWPLRNNHTGTHVLNYALREILGSVVDQKGSLVAPEKLRFDFTSKNGMTPQQIHETDLIVSDFIKRGLTVYSQEVPLSIAKQINGLRAVFGEVYPDPVRVVSIGFDVNEILKDVTNEKWAKTSIEFCGGTHVAKTSDIKQFVIIEETGIAKGIRRIVAVTGEEAFQAERVANEFEQKLNHVGSGALTSSALEQQLKVLAKELDDIVISAYRKSLFKERFANIKKAFDDADKARKAKQVKDAVDQCKQYFEANPESNVFVALLDVGSNAKATGAVVTHVKTQLKSKAAYVFSVDETNGKVSHACVVGQEILDGGRGLKATEWAEVVVKIIGGRKGGKDDSAQGAGEHADKVEEAINEAKKYAESKLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3X3</accession>
    <name>A0A9P6T3X3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_010569</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000075">
        <property type="protein sequence ID" value="KAG0023029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3X3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24296">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="466"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0023029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="525" mass="59800" checksum="4CF7DE580985EFE8" modified="2023-09-13" version="1">MTSTLATLSSNPQFVALASLLTKVLTRSNISKAFGVYLLYIILRYRNSIYGLPTRTDIPGPRGLPLIGNFILVAGMRRDRLLQRQVENHRKYGKIYTMTIPGVGRIVNISDPEMIDHVLRINFWAYEKGEYLRKGLAPLVGGGIFAADGEHWKWQRKLASHIFNVKAFRTYTSSVFVEEAKLVIEYLSTKAGSGEVVDLQELFYKFTLDSFGEIAFGQSFGCLNKPAEAVPFAVAFDRLNAALSERLFVPTAVLKEWWDGTYGQVEKDTQTVNEFAYRVIRERRENAHKNSDRKDLMQLFMDTQDDKGNPLSDEMLKDTLNNFVLAGRDTTAQALSWTFYLMHREQAADRRIVKELVDETDRLLQGGYPTYESTKEQKYAEACFHETLRLYPSVPKNVKTCVEDDVLPGGYKIYKNEKIGWSPWAMGRDTSLWGLDAEVYKPERWLSGEKPPQAKFVAFHVGPRTCLGQQFATIEAITIMSMLMQKFTFELVEPKLEPAYLPALTLPMAHGLPVRVKHRNLTQSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3Z0</accession>
    <name>A0A9P6T3Z0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">Phosphorylase kinase alphabeta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BGZ80_010104</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Glycan biosynthesis; glycogen metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the phosphorylase b kinase regulatory chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000067">
        <property type="protein sequence ID" value="KAG0023199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5971574at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005964">
        <property type="term" value="C:phosphorylase kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005516">
        <property type="term" value="F:calmodulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005977">
        <property type="term" value="P:glycogen metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.10:FF:000004">
        <property type="entry name" value="Phosphorylase b kinase regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011613">
        <property type="entry name" value="GH15-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039477">
        <property type="entry name" value="ILEI/PANDER_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045583">
        <property type="entry name" value="KPBA/B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008734">
        <property type="entry name" value="PHK_A/B_su"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10749">
        <property type="entry name" value="PHOSPHORYLASE B KINASE REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10749:SF8">
        <property type="entry name" value="PHOSPHORYLASE B KINASE REGULATORY SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00723">
        <property type="entry name" value="Glyco_hydro_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15711">
        <property type="entry name" value="ILEI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19292">
        <property type="entry name" value="KPBB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52031">
        <property type="entry name" value="GG_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0112">Calmodulin-binding</keyword>
    <keyword evidence="10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0321">Glycogen metabolism</keyword>
    <keyword evidence="11" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-0636">Prenylation</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GH15-like" evidence="14">
        <location>
            <begin position="10"/>
            <end position="1045"/>
        </location>
    </feature>
    <feature type="domain" description="ILEI/PANDER" evidence="15">
        <location>
            <begin position="1188"/>
            <end position="1277"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphorylase b kinase regulatory subunit alpha/beta C-terminal" evidence="16">
        <location>
            <begin position="1329"/>
            <end position="1448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="379"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="717"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="824"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="861"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="726"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="827"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="869"/>
            <end position="878"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF15711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF19292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0023199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="19">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1521" mass="168496" checksum="B203CE70A829AB7E" modified="2023-09-13" version="1">MYHSQANVRKRLDHYYRCINTVILNRQNPTTGLIPASTAVTSHGDYRDAWVRDNVYSIMAVFGLALAYRRIDDDEGRAYELEHAVIKLMRGLLFSMMRQVHKVEEFKKTQALKDCLHAKYNTATGDTVVGDSEWGHLQIDATSFFLLALAQMTASGILIVYTTDEVDFVQNLVFYIERAYRTPDYGIWERGNKINHGEPELNSSSIGMAVAALQAINGINLFGSRGGPSSVIHVLPDEITRNYTTLHSALPRESNSKEIDAALLSVIGFPAFAVGDAKLVERTRNEIIEKLGGKYGCKRFLRDGHQTVLENTSRLHYDAQELKIFEDIECEWPLFFTYFILDGLFSENESQVEEYRAKLEPLIIDSATLVDFGQFISDSVSDSEDSRGPRTPSTPGFATPGSDGKLPEHIPLIPELYYVPQHLVEAEKKDNHTQARVANDNLPLVWANSLHTLGNLIYENLLSVAEIDPLGRRFNARKTRANDTVVQVVLLAEDKNLQSMLNMYGLETQTMDQVHPITVSHPQGLKEVYGALGNNAKLGLSGRPKRPIGSLGTSRLYRVQGHLYAFTPHFMDNEEFYLTSDNDYLISIFEQELAFVRQYWVYPGRPTMTILLTHAMLGGLSKSRSRSFTSQTDANAQPLTTWRKAGFGANPQKDNKRNLLNFFMTLRSGVCNNVRVRLGRLSEMVNTSCIESLDFLVTKKDIDWLGILRGAAARRKGRHARKLGLNETQTQATTPGGTKTPSHRWSMRRQSTSFGTGFSLGSLTTPAVNIDEGDNYFGSYSQVNTPSEPNFPTSPLSMAPAPLVIDTNVHDPYSSKKAKKAPAKVFKLKDHEESRPKTKNAGGGLGILTSELNNPEIPDAVPADATPEGVEESDDSPDGMDNLGLTLGDPSNLEAAMNMLSISVNLYDQIDLLQYLLSCHGADFYVGNLDATVQTLLEEVYFKSLQLKLWSIVRQAAGLLNKVVNSLTINITDLVIRQKQITIGYGPTEHIITTPLGPDILSRMIYDGNFDDVREGPVVQEVLIYLGSFIRADPEMFEGIMRLRTHFLIIALREEISRLNSCDETDAVEHLMQLSPFELKSLLGTVLSGPTLSANAINTLLRNQSSGRLSPVGRRYINATSSAGEAADGNITENIASSGPSASMGAVPIPNMGKNSTTFTIKVQSGGYHSGNFSKILINESTMSVSSRGINLVVIDPVQGVLIESVSFDTHISEDESDDLARLVDWLHPGLIVVCSCKDDCFEHLTNSARLALKQLGSGLINNLKYRDSWCMIGEKGIEAGKAAEAHKSFMDGPTAVLEKTFDLNDYKAKADDHEAFTSPSTIAAFVPNSSGRWLRRRKNDGSLNRVPNKFYPRVWNILSRAAGFRIGSHFLPRDPIISEKTAEEFNFALAVENFLGVIHDTAERQIAVETLMVIAKIEDRNPGMEVQPEVIDLPLIMREAMERFWAKWVVNGPGGRGQASAAGAPGSKIAVAGLGDMSFQSHEELARRMFYDLPQEGKEGTFAYLARAVFKLLPYSIDLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T404</accession>
    <name>A0A9P6T404_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">GTP-binding nuclear protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">GSP1_2</name>
        <name evidence="9" type="ORF">BGZ80_009198</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the small GTPase superfamily. Ran family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000053">
        <property type="protein sequence ID" value="KAG0023516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T404"/>
    <dbReference type="OrthoDB" id="48625at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000054">
        <property type="term" value="P:ribosomal subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00877">
        <property type="entry name" value="Ran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000131">
        <property type="entry name" value="GTP-binding nuclear protein Ran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002041">
        <property type="entry name" value="Ran_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24071:SF0">
        <property type="entry name" value="GTP-BINDING NUCLEAR PROTEIN RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24071">
        <property type="entry name" value="RAN GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00627">
        <property type="entry name" value="GTPRANTC4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51418">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5 8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0023516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="213" mass="24104" checksum="D5B31E22CD1F5707" modified="2023-09-13" version="1">MADQTPTFKLVLVGDGGTGKTTFVKRHLTGEFEKKYIATLGVEVHPLSFTTNFGQIIFNTWDTAGQEKFGGLRDGYYINGQCGIIMFDLTSRITYKNVPNWHRDLVRVCENIPIVLCGNKVDIKERKVKPKAIDFHRKKSLQYYDISAKSNYNFEKPFLWLARKLAGHQDLEFVAAPALAPAEVAVDPALMEQYKEELNSAAQMPLPEEDDDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T448</accession>
    <name>A0A9P6T448_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Aminopeptidase</fullName>
            <ecNumber evidence="11">3.4.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BGZ80_009336</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="9 11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9 11">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the peptidase M1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.-" evidence="11"/>
    <dbReference type="EMBL" id="JAAAID010000055">
        <property type="protein sequence ID" value="KAG0023469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T448"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042277">
        <property type="term" value="F:peptide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043171">
        <property type="term" value="P:peptide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09601">
        <property type="entry name" value="M1_APN-Q_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.390.10:FF:000001">
        <property type="entry name" value="Aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.50.20:FF:000002">
        <property type="entry name" value="Aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="entry name" value="tricorn interacting facor f3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045357">
        <property type="entry name" value="Aminopeptidase_N-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024571">
        <property type="entry name" value="ERAP1-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034016">
        <property type="entry name" value="M1_APN-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050344">
        <property type="entry name" value="Peptidase_M1_aminopeptidases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533">
        <property type="entry name" value="PROTEASE M1 ZINC METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533:SF174">
        <property type="entry name" value="PUROMYCIN-SENSITIVE AMINOPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11838">
        <property type="entry name" value="ERAP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17900">
        <property type="entry name" value="Peptidase_M1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="Leukotriene A4 hydrolase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 11" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="5 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 9 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3 11" id="KW-0645">Protease</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Aminopeptidase N-like N-terminal" evidence="15">
        <location>
            <begin position="32"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M1 membrane alanine aminopeptidase" evidence="13">
        <location>
            <begin position="152"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="domain" description="ERAP1-like C-terminal" evidence="14">
        <location>
            <begin position="441"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="905"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="962"/>
            <end position="987"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="907"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="928"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="224"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="223"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="227"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="10">
        <location>
            <position position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU364040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF11838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF17900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0023469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="987" mass="113598" checksum="4BF4ABEBC0357BFF" modified="2023-09-13" version="1">MAWDDTSNILPHSFTTLNCNTSLFPYIIIISVTATSVSYNIEEETITLEFPELLYASTAWILDVTYIGLINDKLTGFYRSVYTDAEHNVHHFTTTQFQSTHARGAFPCWDELLAWTIGDLEYIEAYTSGEFNGDRIPCRLYAPVGLAGHGKYSLDLAVQSVEYFSRLFNIPYPLPKLDLVAVPDFSPGAMENWGLITFRLYALLLDEYGGNDRKREIAATVIHEISHQWFGNLVTMDWWSDLWLFEGFATYLAYIAVDDLFSGWDIWSEFVKRLQEVLKHDALRTSHPVEVGVANPSDITQIFDEVSYMKGASVLRMLSAWLGQDQLLKGVRKFMLKYMWGNANTEDLWETLAEECKVDVPEFMRKWTRQTGYPVLSITELDESTVLIRQNLFLSTGDVREEEEDLIWPVPLSLATADNVTPRNIMLNTKEMVLKLDTTKWYKFNMGQTGFYRVAYPQKTLDLLGQTLGSKDGQMLDAANRIGLLTDAAALVASGHTPTSNFLTLLKYFEDEDNYMVWVEISYRLQELFSVWLEQPAPITKALFGVQRRLFTKVVKRLGWTYPEDEDPTIANLRAVAIRYAGRAGDPEIVAEARRRFWEFMGNRDLSAIHPDLRFPVFEIVLRTTTGVEEYEAIVNYYRETYVPIEKVVSLSVLGYGHSPELIHRTLTFALSPEVRSQDILTVIATLRSSVRGRSELWNFMQCHWDTLYERHCDDIRFLDYFILIGIGSFSSLDWYREVQAFFAGKDTSNYERILATCLEGIRMHILWLERDRENVEHWLRVNGYLTAELDEELTRHHAQLEHQQQLLHQQLLQQQQHHQQQQIMSWPVNGTINNGAGVHSTLGHELALASSGRSRSSSSADGFSSSETYYTPGSISSATSSCSSSPPHTYQDENCLHLYQQQEHNHHNHHHHHHHHQRQHSRHQQEHQLQVLQAQQQQQQQQKSQFEMTAHQMNEYKTLNHSSIATAPQTLEGRMESLRVSGEDGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T494</accession>
    <name>A0A9P6T494_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">RH35</name>
        <name evidence="17" type="ORF">BGZ80_011726</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the DEAD box helicase family. DDX41 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="JAAAID010000098">
        <property type="protein sequence ID" value="KAG0022580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T494"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17951">
        <property type="entry name" value="DEADc_DDX41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000449">
        <property type="entry name" value="Probable ATP-dependent RNA helicase DDX41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000657">
        <property type="entry name" value="Probable ATP-dependent RNA helicase DDX41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044113">
        <property type="entry name" value="DEADc_DDX41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 17" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="16">
        <location>
            <begin position="207"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="14">
        <location>
            <begin position="238"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="15">
        <location>
            <begin position="433"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="625"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="12">
        <location>
            <begin position="207"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="56"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="81"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0022580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="646" mass="71857" checksum="07929DD41F4CB69A" modified="2023-09-13" version="1">MATSLTRERAPKRASETNLEDDLDVGDDYVPYVPLSKRRAEKFGKLTAKKGLDYGTPNSGYGSDQNSTSGQQHKSRNGEGNGRDSDRNTGDDDDEDDDAFAKVGPRAGVSLIEQSVEIRKAQVNAEEQKTEAQKALEEEAKILAAVTERKQLASVEEISKGIVYKDPIKTTWTPPRHIREMTQEQLAAIRQKFHIDAEGEDMPPVIKAFRDMKFPKPVLDYLKNKGIKMPTPIQMQGLPVALSGRDMIGIAFTGSGKTLSFTLPLVMRALEEETKMPLAKGEGPIGMIVCPSRELARQTYEGFVGIADMLHKGGYAQLRILLCMGGINMQEQASVLHSGIHIVVATPGRLQDMLAKKKFNLDLCTYMCMDEADRMLDMGFEEEVRTILSYFKHQRQTILYSATMPKKIQDFARSALVMPVTVNVGRAGAANLDVIQEVEYVKQEAKIVYLLECLQKTPPPVLIFAENKNDVDDIQEYLLLKGVEAVSIHGSKTQEEREYAINAFKSYQKDVLVATDVASKGLDFAEIHHVILFDMPKEIEDYVHRIGRTGRSGKTGIATTFINMNSSEQILLDLKHLLREAKQRVPPVLEALEDPTEKYKDLGVAGGCGYCGGLGHRVTECPKLEQQQKSKNSGMMRPNERAGNEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T4C0</accession>
    <name>A0A9P6T4C0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_006980</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000035">
        <property type="protein sequence ID" value="KAG0023966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033228">
        <property type="entry name" value="SZT2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14918">
        <property type="entry name" value="KICSTOR COMPLEX PROTEIN SZT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14918:SF3">
        <property type="entry name" value="KICSTOR COMPLEX PROTEIN SZT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="206"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="237"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="3">
        <location>
            <begin position="334"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="298"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="411"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1065"/>
            <end position="1089"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1865"/>
            <end position="1884"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2282"/>
            <end position="2301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2396"/>
            <end position="2453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2811"/>
            <end position="2847"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="3517"/>
            <end position="3577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="3676"/>
            <end position="3707"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="3801"/>
            <end position="3828"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="3891"/>
            <end position="3921"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="4032"/>
            <end position="4223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="307"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="423"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="466"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="508"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1074"/>
            <end position="1083"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1865"/>
            <end position="1875"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="2285"/>
            <end position="2297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="2400"/>
            <end position="2410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="2435"/>
            <end position="2447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="2811"/>
            <end position="2820"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="3812"/>
            <end position="3824"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="4090"/>
            <end position="4105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="4158"/>
            <end position="4169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="4174"/>
            <end position="4207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0023966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="4251" mass="475595" checksum="38FFC29821549EAB" modified="2023-09-13" version="1">[encoded data, 4251 characters]</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T4H2</accession>
    <name>A0A9P6T4H2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Vacuolar import and degradation protein 21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">EAF1</name>
        <name evidence="13" type="ORF">BGZ80_006660</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EAF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000033">
        <property type="protein sequence ID" value="KAG0024009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035267">
        <property type="term" value="C:NuA4 histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014012">
        <property type="entry name" value="HSA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46459:SF1">
        <property type="entry name" value="E1A-BINDING PROTEIN P400"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46459">
        <property type="entry name" value="E1A-BINDING PROTEIN P400-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13921">
        <property type="entry name" value="Myb_DNA-bind_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00573">
        <property type="entry name" value="HSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51204">
        <property type="entry name" value="HSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HSA" evidence="12">
        <location>
            <begin position="391"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="11">
        <location>
            <begin position="758"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="73"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="812"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="968"/>
            <end position="988"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1208"/>
            <end position="1230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1327"/>
            <end position="1397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1411"/>
            <end position="1451"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="1054"/>
            <end position="1118"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="1245"/>
            <end position="1307"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="1536"/>
            <end position="1583"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="1629"/>
            <end position="1656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="88"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="103"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="134"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="155"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="196"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="288"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="814"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1333"/>
            <end position="1347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1349"/>
            <end position="1378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1411"/>
            <end position="1423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0024009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1715" mass="189685" checksum="D9A67AAC6887573D" modified="2023-09-13" version="1">MAEVNKTLPDILKMRLQSEKAHQEQIDEILVRRDFLLKQFFYMKQLAGTEASLEPEQDFTKIDIEKLKAFQEEHRLSESNPTSGTLETDLEDISMEEPESLVKQESTTPTVMTPSENAVVVPDLTSDSPMEIVESEHLDTKEMNEKENAIKKEPTSSIPDFSSDRNATQGDNPLSPKSRAASPESHLSTHLDRQTTPEPRTPGSTRGSTPGAQSNSAETSPSRKLKRMLPPPERMVTRGVSGAIRHRSVDEILGAASERSPTTPGGRHSQQDRFSPIATSPGGGLAVAATSSPSLPTTTPTAMKRSESRYGSSRYDPMDGMPSSGRPIRHVDLYAWQLKAQSQPIYKALQTASKVLTTKDWKVAREELKLMRAMQRIEALKAGNRWSFKQIKKHRGPARTKTHWDHLLDEMKWIQVDFKEERRWKIVTAYQVSRWVMAWHEADDKSLVCVSRRKVTETLEKRSSSSQAQSLEAMGTTLKMEDFVDESMMAEPVPVKEETPTTAVDVIPKQEKEITTENPIKIETEDIVMSAPTEVSSEQTPNDGSIKSTTSEIMQISTENADIDNKAFVSKLKESAKDDFIMMPPPIAPAVLQKCRPLILELDTSTTVFSLDSLESLMEGVHLGSLDVGALFPDLPMYGPPNPEDNDAYVDEAEHGRVTMISRLMSSKPPVLEFGPLASQIVYVKRKREPTAEIDGFDEEDARVPRIEGKILNAIPGTDPPRTVPVLFQTKKNKDAPMTPIRRPTPPGPLAQKNSVTWTNEEDDLLMSLIKPYQFNWDLISDLFNSMRGPIISSERRTPWDCYEKWAKKELPLSGGSSSAGSEASSGLIPIGNLPAGSGSTPSSPKARKDKDGKKIVSAIKTDPVRKKQRSLSLLEAMKKASKKREIAQNRVNSAPVVAAAAANKKAALGQDGQSPKIGGTVPLTPADLSKFKSDRDRHLSQVINEQRQMQAASLALGRQLARPAVTAQVTAQQRGPMSPQAKAGVRPLNPQQVQAQVQAQTQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQAQVQAQAQAQAQAQVQAQVQAQTQAQQAQAAQAQLQLQQQQLQQQQQLQLQQLQQQQLQLQQQQLQQQQQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAHSQAQSLPQQGQAQVSAVLSPQAIQFIRANPLSNPQQIQAFIRQQQLQAQVQAQAQQQLQQQQLQQQQQQQQQQQQASSSPLVGPMTSPMPGFASPSLQAHHLQAQVQAQVQAQQQQQQLLAQQLQLQQQQQAQQLQAQQIHAQKQQQQLQQQQQLQQLHQQQQLQLQRAAQAQALQQQQLQQHAMQQKQQQVNQLQQIKTPTGSPRQTSTAQMGGLTPTLPSGPSTPGESINHAGANANRVNGVGNGSGNSSGAATPSTPVLAGGTLNNNAVNLNLANNNANNANNANKQQPQQPLSVNGGGKGGSTPVLAAGPQQLQQQQQQQAFVQQQQQQLQKQQQLQQQVVGATQTIPTSAMAAVPSMPTVPTPQMIAQLAQHYPNLPRVQAEAQARQQLVRYFESRHQAAQELSAAQRQQQQVQQVQQQQQVQQQQQQQQQQQQQQLLLLQQQQQQNGQLNGQATRVLPQQQASPQLAQQQLVQASTMVNGQGLMPAQLAQQKQMIQQQQQQQQQHLLQQQKLQQQKQLQLQQQLVQQRQLQQAQQLALQQQQQQQALVLQQQQIALQQQQQQQQQQQQQQQQKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MC63</accession>
    <name>A0A9P6MC63_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008838</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004935">
        <property type="protein sequence ID" value="KAF9991881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MC63"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="152"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9991881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="190" mass="22585" checksum="308F53FFB44DC5B0" modified="2023-09-13" version="1" fragment="single">MRLMDSVLVDKLNAILDAQRKTVDSKDGVQGAILRELYEMETRLNSLRSEERDLEEYIKEYNTDDLVMLEELTFDEQWRFFQLNKDHSMNFPEQEHIIHKKNVLSENVEISKEQGGEGHNFWNIVYRRHSYEDGTLHAKLYTTRSSIHREKISENESKLSYLRSTLQRVENELAEYSSKHQSEMADIQKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MCV9</accession>
    <name>A0A9P6MCV9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_008723</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004830">
        <property type="protein sequence ID" value="KAF9992083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MCV9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9992083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="61" mass="6992" checksum="DD74D7560E48BF74" modified="2023-09-13" version="1" fragment="single">MPMGANERNWIKLKVAEGSDWKGIQAMLRMDDNTMSEIEEKKSSDIVPPAFCLSYEDVRKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MDT0</accession>
    <name>A0A9P6MDT0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 13">Threonylcarbamoyl-AMP synthase</fullName>
            <shortName evidence="13">TC-AMP synthase</shortName>
            <ecNumber evidence="3 13">2.7.7.87</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11 13">L-threonylcarbamoyladenylate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BGZ80_008053</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 13">
            <text>L-threonine + hydrogencarbonate + ATP = L-threonylcarbamoyladenylate + diphosphate + H2O</text>
            <dbReference type="Rhea" id="RHEA:36407"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="ChEBI" id="CHEBI:73682"/>
            <dbReference type="EC" id="2.7.7.87"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the SUA5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.87" evidence="3 13"/>
    <dbReference type="EMBL" id="JAAAID010004258">
        <property type="protein sequence ID" value="KAF9993702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MDT0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061710">
        <property type="term" value="F:L-threonylcarbamoyladenylate synthase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006450">
        <property type="term" value="P:regulation of translational fidelity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.870.10">
        <property type="entry name" value="DHBP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11030">
        <property type="entry name" value="Threonylcarbamoyl-AMP synthase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017945">
        <property type="entry name" value="DHBP_synth_RibB-like_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006070">
        <property type="entry name" value="Sua5-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038385">
        <property type="entry name" value="Sua5/YwlC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005145">
        <property type="entry name" value="Sua5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010923">
        <property type="entry name" value="T(6)A37_SUA5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050156">
        <property type="entry name" value="TC-AMP_synthase_SUA5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17490">
        <property type="entry name" value="SUA5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17490:SF16">
        <property type="entry name" value="THREONYLCARBAMOYL-AMP SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03481">
        <property type="entry name" value="Sua5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01300">
        <property type="entry name" value="Sua5_yciO_yrdC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004930">
        <property type="entry name" value="Tln_factor_SUA5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55821">
        <property type="entry name" value="YrdC/RibB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51163">
        <property type="entry name" value="YRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 13 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 13 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 13" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 13" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="YrdC-like" evidence="15">
        <location>
            <begin position="1"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>L-threonine</name>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>L-threonine</name>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>L-threonine</name>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR004930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR004930-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF9993702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="325" mass="35345" checksum="F3F256895711072D" modified="2023-09-13" version="1">MLRSILKDKKIPEVYSDLIRTYWPGPLTLLFPRSNLIPDEITCGQPTVAVRFPSHPITRALISACDTPLAAPSANSSGKPSPTMASHVMHDLQGKIPMVIDGGQCSFGIESTVVDGLRTPPAILRPGGVTYEQIRQVKGMENVQIYKKHFTDAAMEQAPTTPGMKYRHYSPEAEVVLVEYISPENSSFSSAASSASSSSCGNATTGQYSLILKEIEKLKKEGKKRFGILRTSFTSPTATPSATSNNQMNGNGSADQDIIEFPLGQGSKPDDVARELFRGLRFLDTQNVDCIFVEGISEEEEGLAVMNRVRKAASRTISSDPVEFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ME94</accession>
    <name>A0A9P6ME94_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_007759</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004023">
        <property type="protein sequence ID" value="KAF9994634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ME94"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF309">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14510)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="7">
        <location>
            <begin position="19"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9994634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="84" mass="9041" checksum="0DAA47E9B9F88A93" modified="2023-09-13" version="1" fragment="single">MPNFNTPSTFHVVNPSNPKVLIVGAGLGGLTLAILLEKASIDYEIYERSTTISSQGSAISLSVNVLPLMEQLGLLGDLEKIWKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MEA1</accession>
    <name>A0A9P6MEA1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Large ribosomal subunit protein uL15/eL18 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_007886</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004121">
        <property type="protein sequence ID" value="KAF9994232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MEA1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.100.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000039">
        <property type="entry name" value="Ribosomal_eL18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021131">
        <property type="entry name" value="Ribosomal_uL15/eL18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036227">
        <property type="entry name" value="Ribosomal_uL15/eL18_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10934">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10934:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17135">
        <property type="entry name" value="Ribosomal_L18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52080">
        <property type="entry name" value="Ribosomal proteins L15p and L18e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL15/eL18" evidence="5">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="58"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="81"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9994232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="91" mass="9866" checksum="725818A987524065" modified="2023-09-13" version="1" fragment="single">VPKLSIACLRITKSAKARVLKAGGEVITLDQLALRAPTGANTILLRGKKNTREAVKHFGMGPGKHAKPYVQSKGRKFEKARGRRASRGFKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MEN4</accession>
    <name>A0A9P6MEN4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007523</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003872">
        <property type="protein sequence ID" value="KAF9995401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MEN4"/>
    <dbReference type="OrthoDB" id="2439614at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="22"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="60"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="183"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="222"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9995401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="268" mass="29147" checksum="BCED7B51BC966B00" modified="2023-09-13" version="1">MDNPRLDLDSSVRLPLHDHNNQSSSSLQHQQQQKTKPPPLRKIPVREFESYSPPPIMTAPIYGSSKFSSISPPPFYSPLTNVTSGGGGNNINTTNGSPYNNDTNGHQNDYDYYRSYQNQDESYISSSGQQQQLVTEESSQQRQQNYIGTATGTSGNSMPRGDREREREGGYRSRPVSQYQTDPSSLTSLSPTSGIPVASTTTAIPTSKSRRPKSLATHEFTAEAGNGSASSSLLLGNEGSAYSQPRKGQGQDTAALDMNTKDMVGTKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MFN9</accession>
    <name>A0A9P6MFN9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_007008</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003513">
        <property type="protein sequence ID" value="KAF9997450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MFN9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9997450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="78" mass="8442" checksum="517A308669A39011" modified="2023-09-13" version="1" fragment="single">SISGLRHGVTPARPKPSNRAYMETIQQDYNCLDTSPANKKEPRALDHAPYGALVAVTDGDCPRSPLLQDHNDNQCPGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MFW5</accession>
    <name>A0A9P6MFW5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">VWFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006920</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003453">
        <property type="protein sequence ID" value="KAF9997815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MFW5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45737">
        <property type="entry name" value="VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45737:SF6">
        <property type="entry name" value="VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13768">
        <property type="entry name" value="VWA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="1">
        <location>
            <begin position="127"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="725"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9997815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="725" mass="78715" checksum="D7ABE0DA893B9C1E" modified="2023-09-13" version="1" fragment="single">MPRYGSYPIELAEDNLDITSKGRIQITVDVIMAQESLIQQIQSPSHPIAVSLGTTSIAPRADPAMSKASATLSLGSAGLEKDFILQVVAKDTGLPTAILETHPTIPNQRALMATLVPRFSLPSEKPEVVFICDCSGSMEGSNITLAKSALKVFLKSLPMGVKFNICCFGNHHSFLWAKSQTYSQSTLDEAIKRVERIDANMGGTEMLEPIKATIDQRCKDIPLEVILLTDGDIWDQDKLFSYLNKQVIENQDPIRVFTLGIGSGASHALVEGVAKAGNGFSQSVGEGEKMQSKVVRMLKGALSPHVTDYTLEVKYSDKDSVTDVDDDDFEIVEKVIDSLNIKVDFEDEKKALHEQNPISLFDTSIDIDKEMSVPTDDDSGEARYAHLPPLTPPKLLQAPHIIPPLYAFNRTSVYLLMGPECSQRTPKSVVLRGRSRHGPLELEIPIQILDTPGETIHQLAAKKAIVELEQGRGWITQVTDEFGTPIKSKYESQFADMVEREAVRLGVEFQVGGKWCSFVAVDVQHENTKQDSVTEECAKSSDYDLCDIGEVVVEESRQGTITATKSANPNGSSLFGRLYSNFNLDAGSISNVVGNASNGIAHGASEATGAAGSAARSAARGVGHVAGAVAIGTGAVVIGDGLLAAGALHKVDGVWKRTVQVLTTRKANVDEVCPIAKTSHVYYDDDVYDAVLTERDTGVPCVTQLIYDTEAKAYYDYYRYGETDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MFW8</accession>
    <name>A0A9P6MFW8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_006995</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003506">
        <property type="protein sequence ID" value="KAF9997491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MFW8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051104">
        <property type="entry name" value="FAD_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46720:SF3">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46720">
        <property type="entry name" value="HYDROXYLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01460)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="6"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9997491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="96" mass="10113" checksum="6117C6024D346CEC" modified="2023-09-13" version="1" fragment="single">MSEPTIAVLIVGAGVGGLMLGAALESANIPYHILERATELRPLGSAIALSANVLPVFEQLGIYEELKSVSLPHVSVDIFNTKLDDLGSIDGPHHKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MG00</accession>
    <name>A0A9P6MG00_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ABC transmembrane type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_007091</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003571">
        <property type="protein sequence ID" value="KAF9997073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MG00"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18603">
        <property type="entry name" value="ABC_6TM_MRP1_2_3_6_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000001">
        <property type="entry name" value="ATP-binding cassette subfamily C member 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:003838">
        <property type="entry name" value="ATP-dependent bile acid permease, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF443">
        <property type="entry name" value="MULTIDRUG-RESISTANCE LIKE PROTEIN 1, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="214"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="297"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="177"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="624"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9997073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="624" mass="70173" checksum="FB7F3539FB0E4284" modified="2023-09-13" version="1" fragment="single">IGPKGLLAGKTRVLVTHQIQYLAQSTSILMMRDGSIVEQGSYQELMRKKTDVYQLVTEFGNDSSDEEAADDGLMTTESGEQNEHLEDDAENLPAGEALQLSTTPRSARRGSIRSNASVRTLRRPSVTSVHQRGKVAKADQPKNNIIVEEQMRQGSVHRSVYLAYAKACSYTSVFMYILSMIFSQGASILTSLWLTYWSSKNDSGNVDRNTMYYIGVYAALGLSYSILTVFQSIILQVHCAIRSARVLHQEMLHSVLRSPMAFFDTTPMGRILNRFSKDQSTIDEVLPRSFSGYSRTLFQVASVLLVVTISTPSFIIVIIPFSFVYLWLQRYFIATSREIRRLDSVSRSPVFAHFQETLGGISTIRAYRQQKRFIQGNEFRLDQNLRAYYPGIAGNRWLAFRLETLSSIIIFGSAFMSVVSLSRDVAVDPGLVGLSLTYALSITQTLNWMVRQYTEIESNIVSVERLQEYIELKPEAPEIIEDNRPPQEWPAEGRVDFINYETRYRPGLELVLRGVNCSIRPHEKIGICGRTGAGKSSLTLSLFRIIEAVSGQILVDGQDISKLGLYDVRSRFSIIPQDPVLFAGTVRFNLDPLGTKTDQELWQALSDSYLKDHVSQMEGGLNAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MH98</accession>
    <name>A0A9P6MH98_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006650</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003293">
        <property type="protein sequence ID" value="KAF9999042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MH98"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.600">
        <property type="entry name" value="Ribosomal protein S10 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036838">
        <property type="entry name" value="Ribosomal_uS10_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9999042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="131" mass="14341" checksum="DD8557638A2E7CBF" modified="2023-09-13" version="1">MTESTASDTSNHYRTIDQAPDSSITQHGEIPTPSTVLKADFSITLLSESTSTLNASIQRLMDTIHATPGLSIRGPIRLPRDGKIHSRRVDIKSIQEKQLRTIAEQSGIELSEDAGEKKIQSNGVVVIFDIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MHI5</accession>
    <name>A0A9P6MHI5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribosome recycling factor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_006557</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Necessary for protein synthesis in mitochondria. Functions as a ribosome recycling factor in mitochondria.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RRF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003244">
        <property type="protein sequence ID" value="KAF9999495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MHI5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1360.40:FF:000001">
        <property type="entry name" value="Ribosome-recycling factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002661">
        <property type="entry name" value="Ribosome_recyc_fac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023584">
        <property type="entry name" value="Ribosome_recyc_fac_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036191">
        <property type="entry name" value="RRF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20982:SF3">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOME RECYCLING FACTOR PSEUDO 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20982">
        <property type="entry name" value="RIBOSOME RECYCLING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01765">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55194">
        <property type="entry name" value="Ribosome recycling factor, RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribosome recycling factor" evidence="5">
        <location>
            <begin position="128"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="66"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9999495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="211" mass="22632" checksum="B5C98671D3EA8957" modified="2023-09-13" version="1" fragment="single">MQRATTAFLSATRRISSAQQITRNATIALTTPASIPKPLLNKVHHGSLGMNMAMALNASFQVRGFASKKDSKKGGKGGKKNSSDNDDNDEDNGSRKGKGGKSALVESADMSFDPLDLEKKMGQCLERLKKDFTTMRAGTANPAILDPVMVKVENKMVPLRDLAQVSIKDAKTLIVNVSDTELITSVEKAIREAGLNLNPIADNKAVKVPVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MHT7</accession>
    <name>A0A9P6MHT7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Beta-lactamase/transpeptidase-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_006130</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003010">
        <property type="protein sequence ID" value="KAG0001740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MHT7"/>
    <dbReference type="OrthoDB" id="5946976at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.600">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050491">
        <property type="entry name" value="AmpC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021860">
        <property type="entry name" value="Peptidase_S12_Pab87-rel_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46825:SF15">
        <property type="entry name" value="BETA-LACTAMASE-RELATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46825">
        <property type="entry name" value="D-ALANYL-D-ALANINE-CARBOXYPEPTIDASE/ENDOPEPTIDASE AMPH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11954">
        <property type="entry name" value="DUF3471"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase-related" evidence="2">
        <location>
            <begin position="26"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S12 Pab87-related C-terminal" evidence="3">
        <location>
            <begin position="405"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF11954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0001740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="513" mass="57733" checksum="853818BDB08409F9" modified="2023-09-13" version="1">MQLPTPHQYNKPKEPLADLPDIIEKARVQCCVAGMSLAILHKGKLIFAEGFGKRDEENTFTAETLSPIGSLTKAFTATAIGEMVAEGKMDWDKTPVNKYLPEFELKDPVLTSQLTLADLLSHRTSLPRIVEQGWVRTEIARKDLIKRLKYVEMPSKLSSMTQYNNVMYAVAGEAAANIAGIPYEDVVREKVLKPLGLTNTGFSPTEMKKRTTAHAMPYNASSYEDAQKGIFQQESLEESYMTLAPAGDMYSNVLDLVRWGRVVMKNGELDGKQTLNKKSIQETLTARTILQPLRRVDRPELAPLIAYGLGWTIDSYKGHNFYWHNGGLPWFTADLIVYPDDDLVIAQLSNVQHFQLAKNLARYIADELLDLPRTKDWIFVEAVKETKSSYEDLAKEMAGDLPERILNKPATHPTQAYVGEYSNPVYGKIKICLGCDKSGEDGSLYFELWGCKDKLEHYHFDSFVARLDYWVDGVGLITFQTGGDGKVMSLTANFSLLDIQTEFKRKDDADEDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MJY4</accession>
    <name>A0A9P6MJY4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005552</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002735">
        <property type="protein sequence ID" value="KAG0004794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MJY4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="241"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0004794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="306" mass="33643" checksum="CE67FCB6ED3E1762" modified="2023-09-13" version="1" fragment="single">DHVASNIPCSPADEEFIAIEKHLIVIGSTLDQLSLHSQGSAGGPALMAHQPGLWNECTWIPRPTYLDICSHAQETPGTCSRHYSPLPWKAHSLHHNMPSLTFPDQDMVIDDDSYFSHAEPVDNIANDRSISEVNPAMDTIDVDEIDDDFSDLEPEKRLIEDDLGDLDDLPLEEIFSDDFGDHAPKKQLIKDDFADIATLPVDGFEDLTLGQSPASGYPPAVKETIQEEAALYDFDVDANRTNNGKNESTHDGFYADNAGETDNANIEDPSEQPITSDEQSALGHSGIPLKRSTNLIRPACRHLSCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MKH4</accession>
    <name>A0A9P6MKH4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_005324</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002631">
        <property type="protein sequence ID" value="KAG0006290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MKH4"/>
    <dbReference type="OrthoDB" id="10537777at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12087">
        <property type="entry name" value="TM_EGFR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="27"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="207"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="9"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0006290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="257" mass="28383" checksum="4E6DE3BE7CC3293B" modified="2023-09-13" version="1">MVYDIKTDSWTTSYTPPPSSSSSPTGAIIGGCIGAAVALILLVAGFIWYRKRSHKARSNALAKGDESAGSMQQESTEPDQHSQAQQRGLYPPYEPQSDQKQKTNCEMASIPTDQQPQYIYQPPILTIDPAGGYCPPPMSYYQPVEQPQHDYQPPVITTDQAAGYYQPAEQQPLIYQPSSEASDATHFDNEAHHHRVSVLDTIATSPQSTFRSPQLDHASYHDDDNHRASTLSSATSNNPQSYRSPQTDLPDIQDVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MKR0</accession>
    <name>A0A9P6MKR0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Carrier domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_005182</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the NRP synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002571">
        <property type="protein sequence ID" value="KAG0006682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043041">
        <property type="term" value="P:amino acid activation for nonribosomal peptide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12117">
        <property type="entry name" value="A_NRPS_Srf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19544">
        <property type="entry name" value="E-C_NRPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.30:FF:000010">
        <property type="entry name" value="Enterobactin synthetase component F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12780:FF:000012">
        <property type="entry name" value="Non-ribosomal peptide synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.980:FF:000001">
        <property type="entry name" value="Non-ribosomal peptide synthetase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.38.10:FF:000001">
        <property type="entry name" value="Non-ribosomal peptide synthetase PvdI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1200.10:FF:000005">
        <property type="entry name" value="Nonribosomal peptide synthetase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.980">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.38.10">
        <property type="entry name" value="Luciferase, Domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF1">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="559"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0006682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1316" mass="145536" checksum="EDEECD43D7CF8067" modified="2023-09-13" version="1" fragment="single">MAVCRYMEQALYSLVIALESSPETPVSCLDVLPAEERTKLLHSWNATNNLYPDQLLVHQIFEQHVNQTPDAIAVEHLERSLTYSDLNAMANQLAHQLNERGLRAGDRVATYFQRSFELIIAQLAIYKIGATYVPVDSKAPVDRQSFILKDSNTCLLLTNAHSDIPSVFDVPLFRFESDLLQKTSVHNIGVTGSGMDVAYIMYTSGSTGVPKGVVVSHRGITRLTINNGYADIGSDDHVAFTANLAFDASTFEVWAPLLNGGRVIIIDSDTFTTPHLLAETLEQHQVTAMFITTALFNQYVHSIGAAMAKLRYILCGGEQENLDSFSTLLKHGGPEHLIHCYGPTETTTFATTYEVKHISDDMDRLPIGRPIGNTYSYVLDKDRRPVPLGAVGELYLGGAGVANGYLNRPDLTAERFLSDPFSNHIGGRMYRTGDLVRYLPDGNLIFIARNDSQVKIRGFRIELGEIQARLEEHELVKEATVVVLGEGAEKRLVAYVVADVQEQLALTLREYLTKHLPEYMVPAAYVRMDKFPVTNNGKIDRRALPEPDSASFVTRDYAAPQGEIEITLAEMWSELLKVERVGREDNFFMLGGHSLLAVQMIGRLHHLGHSLSVRTLFDNPVLSVLASSLTKHQETPEAPPNLITSDTIKITPEMLPLIDLSQDDIDHIVGRTPGGVANIQDIYALSPLQDGILFHHMMATKGDTYLLLGCTAFESRELLDRYINAFQEVVNRHDILRTAIMWENLTSPAQVVLRKATLSVTELSLDPADGPIIEQVAKLYDSREYRIDLSQAPLIRYSVVQNNDGRWILAQLMHHLIGDHSTLDVMEEEIKAFMGGLGESLPDPQSFRNLVAQARMGVSVDEHERFFCQMLQDIDTPSLPYGLSDIYNEGHNVTDTHRMLPQDLNDKLRGHAKRLGVSLAALCHLAWAQVIAATSGQAQVVFGTVLFGRMQGGSGSDRAMGLFINTLPLRVDVGDTGVLSAVRKVQTDLAALLEHEHASLALAQRCSSVPSGMALFSAILNYRHNATSFSQTSIDPGMENVLDHERTNYPFVLSVEDFGSSLGLTAQVVQPYNPSTICEYMHQALHSLAETLEHATETPIQSLGVLPNEEYDLIVRSWNKTETSYPSDRCIHRLFEDQAAKRPEAIALVHDERSMTYRELNNQAIHLALKLTGLGVEPGDNVAILLVRSFELIIAQLAILKVGAAYVPIDVKAPVDRQVYIVQDSGTKLLITNRNMDVPVQIQMPLLHVNADEKIFDETQDALDSLLFSSVSSDATAYIMYTSGSTGLPKGVAAPHRGIARLAINNGYADIGSDDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MLX5</accession>
    <name>A0A9P6MLX5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">MEIOB-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_004792</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002400">
        <property type="protein sequence ID" value="KAG0007341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MLX5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056880">
        <property type="entry name" value="OB_MEIOB_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24903">
        <property type="entry name" value="OB_MEIOB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MEIOB-like N-terminal" evidence="2">
        <location>
            <begin position="94"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0007341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="421" mass="46550" checksum="955B260B5143CEEE" modified="2023-09-13" version="1">MQRHQATPYQRYPPRPPATLGVPPPVGAVDQEHQVPIQRYVQSQSFYQPRPPYGSGIPPVTAYSRQLPALPTFSPQALKTFAPQQLNCAPDAHMVPIHCLKPVKSYVRVSGRTVRAPDIKSFTDKRDSKQRWIQSFTIKDDRDTIEVKIWHKTQEHLDSYSNISLDQVIHVLTDEVKLNTKPSFGSQASGMPTTSSPLYLSLTEGKLGHKIEFGNESEMAALFKKGLGANIAGIVPSISLKQILGALNSMGNERFSLVMVSSTVVNSKNGPVTKTLLTVFDTQGQEASLTLWGDSMATTAQQWDPLKTTLILTGAQVGMYAMKPQITIGYQTHVQVNPECKNVEWLKHFAARCSGLLDELNPVSDIQEVPIDHIGTCYRIADISQLAESLAVAELAYGFTYAILSEFDIESRASEILTAKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MME3</accession>
    <name>A0A9P6MME3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Mitochondrial carrier</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BGZ80_004633</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002340">
        <property type="protein sequence ID" value="KAG0007467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MME3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050567">
        <property type="entry name" value="Mitochondrial_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624">
        <property type="entry name" value="MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="45"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="76"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="189"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0007467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="279" mass="30669" checksum="B4CFC36E37258183" modified="2023-09-13" version="1" fragment="single">HPFDTLKVRLQTQPNPPKYSGAMDCLRVTLKEEGPFGLYKGVTSPLMGIGICNAVMFAANGTFRRMLQGGDETKTLSLIQVGTAGSMAGGVMAFVNCPVELLKVKLQTQYGPSGGVVAAAARSNVTKPYTGVLDAGIRTFRQQGMKGLYRGMDITLLREIPSYFSYFVAYEGTKRILAHFNHNGRVEDLSTPELLLAGGVAGFGAWIPCYPQDVIKSRMQSNLTYKNTLECFRSLQVEAQGGNWKVWFKGFGPTMARAFPANAATFFFYEMTMKFMRGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMF1</accession>
    <name>A0A9P6MMF1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Dilute domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_004929</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002466">
        <property type="protein sequence ID" value="KAG0007220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMF1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051020">
        <property type="term" value="F:GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002710">
        <property type="entry name" value="Dilute_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052072">
        <property type="entry name" value="Vascular_dev_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16027:SF6">
        <property type="entry name" value="DILUTE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16027">
        <property type="entry name" value="DILUTE DOMAIN-CONTAINING PROTEIN YPR089W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01843">
        <property type="entry name" value="DIL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01132">
        <property type="entry name" value="DIL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51126">
        <property type="entry name" value="DILUTE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dilute" evidence="2">
        <location>
            <begin position="53"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="410"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="166"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="187"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="447"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0007220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="514" mass="58302" checksum="275CB89CBB9F6B21" modified="2023-09-13" version="1">MFVFSSKDIKHIIDITVTNMEPGRSRAHRPIPAYVLFLAARFAHYFSSAELLEELMEAAYTAIHSVTKSKPEDMTLTAYWISNTSVLLHFLRKDPGLSVATECDQLKIEALLLDMIQMVVIDAERRMERVLEQAMLDHDTIQGMDEVKFQSDWAFLWRGSISKGSNKNNGGNNARKSTSSLSPNPGTSATFNGSTAGSTSNSTSPSPRLLTRTSSQPLIPLANRPPSPRQRRISPRTLTTMLSSLLFVMQTYDIHPDIINYVIAQLLNYISCEVFNRMMSSKKLLSRSKALQTRLNLSILEDWIRVNHMPAKLMDQFAPLIQLLQLLQVLSLQEDFATWIETLKKLELLNPTQVKRVVTGYRFEVNEPRLNDEITQYVLQVASDTEKMVRRQMMDRKRERPLTMMSIVDPATINNRKSTEDGTKSRTSLSGPSPMTPAAFSPALLTEAEKARAKQRQREQEEEATLLSQTRNSKAWLPFTIPENLAEREDGVERVFVPLIPEEMMSLLDTYSSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMS8</accession>
    <name>A0A9P6MMS8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Brix domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_004461</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002273">
        <property type="protein sequence ID" value="KAG0007608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMS8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007109">
        <property type="entry name" value="Brix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045112">
        <property type="entry name" value="PPAN-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12661">
        <property type="entry name" value="PETER PAN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12661:SF5">
        <property type="entry name" value="SUPPRESSOR OF SWI4 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04427">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
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    </dbReference>
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        <property type="entry name" value="BRIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Brix" evidence="2">
        <location>
            <begin position="26"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="303"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
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            <end position="365"/>
        </location>
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    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
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            <end position="398"/>
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    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
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            <begin position="411"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0007608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="433" mass="48971" checksum="A1890C14DDA44B7F" modified="2023-09-13" version="1">MGKARKKSRTHKKADEGENPNAPKVPKTFVMRSGEVGHSVMHLVSDIRRLMEPNTATKLRERKNNRLRDFVAVAGPLGVTHFVILSRTEHGTNLRISRVPRGPTLSFQVKTYSLAKDIAAMQKAPKSPGLEFHVAPLLVLNNFGDSNEMKLMSTVFQNMFPPINIQTMQLADARRVVLLNYNSETKHIDFRHYNVSVKPVGISKSIKRVITTDVPDLQGFDDISDYVLRGAFASESDIEDGPESTVTLGQDYIGRNNRKQDQRAIKLVELGPRMELRLVKIQAGMCDGEVLFHDYIKRTPEELKAQKSEREKKMQQKAARRMEQEANVIKKKAEKEAAKEKHRLATGGAPRKPEGENDDDEEEDVENTKGKRKRGVQDDEDEDEDEDGEEQYNDDSDNYSDMGDMAPQFSDEGEFSGDDDDQMEGFSDDDDLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMW7</accession>
    <name>A0A9P6MMW7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PAS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004354</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002228">
        <property type="protein sequence ID" value="KAG0007690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMW7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="238"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="330"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="346"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0007690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="371" mass="42310" checksum="5FA451D7ACE51EED" modified="2023-09-13" version="1">MSLRLRRKDGTYAPCLIFGCLCYQYIVSCYSFGEEVNKAAQKPIVYGVHSAVMTRIVGSEKEEFERISRNHRALKSDTWNPAGLQLELRACLLLNRFTRNITIMYASPSCELIFNIDPDKLLGKPLLLYIRADDLANFVEQVDQAKSSNALRHMRFWFQSPNCPTEIPCEALLYGAADAMVMILRKYLPFKRKQFITSHSSRGQAQDNGRFQFYDGSGSSAESMYSCSPESISSSVSSSISTSLGARTSQAHRTPRTPQGPIDRIRNLSTEQNRLRPLASVKREDQEAMDPETPLVRELVTDEVELVESELVEGLEKMSLRYIMRNEKDEKEKKDFEENDFFGGGFEDDEGDAMDIEEVEMPSSMRRHQRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MN80</accession>
    <name>A0A9P6MN80_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Galactose oxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_003427</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001902">
        <property type="protein sequence ID" value="KAG0008457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MN80"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019760">
        <property type="term" value="P:glucosinolate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47435">
        <property type="entry name" value="KELCH REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_5G12780)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47435:SF4">
        <property type="entry name" value="KELCH REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_5G12780)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="317"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="614"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="291"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="346"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="520"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1068"/>
            <end position="1095"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="419"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="525"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="559"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1068"/>
            <end position="1079"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1080"/>
            <end position="1095"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0008457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1170" mass="127810" checksum="0FEEB07BC59C68FD" modified="2023-09-13" version="1" fragment="single">MAYGSDVSRLYIQGGVSRANIALDQFYYLDFTVSWNVTAPAWKNLSASFSGSSGTLDPSKRFIVAAANQSNIYIYDPNGSNAQGAQAGWTTHSIQESIPSTGPILTTNTTNSVEQMYYFGSDSSFMATVEPSSVLQDKLNATPLNGKSANIPQGAGAVSTSSIGVIRAEADTSGKMVVQLFSDTTQTWTTVGAGAVAPARTGHCFVPSNDGTRYYLFGGTDTSNIPLSDFYSFDINKKIWTTLPGPSNPRTSMACAVAGNLFIVWGGSTTAGNAPLLYDIANSSWEVDTFVPTTSNPSPVPPGDGGQAPSDKPSSSVGAIVGGIVAGVVVVAVALGFLFIRRRKPAKNQTDLARSGGKSEISQESIEMGGYKSIPPPFKSDESYQQSPVVAGTRTPYSEPPSFPSSSPSPSMGVGMGVNQHQQGPVQPRAQSQMSNVPPPIIQSPFEPEPDTSSQHLLANPAPPEPRLLHSSPLPAVAPLGSGPYHDRQYGGDQETTSGQEMSRDMEPATIDLIPIAASEAEEGSQVSRSNSLVSTREGRGVGSRNKSIRDGGTGGLLKEPEDSRRDSTESLDYLDISGNLLLLNNNNNGSTTSLLLSNNSGTTSNKRLGRAKFLLLITLGVFSLLAFGKLFKPQQDLIPLDDLDPPSPPEETSDELVRELLVQQIMETRKSAYSFDDFTEEGLQLPQNKHLLPATAVLLGWKRIQGLKLIVSYLVRYPYIKQIIVWNNNKEIHLSRRDFELDPSFGPLPDLQVYNAAENLHDFAKYMSCSLAKYEHCYFQDDDWLNTHMDALYTNFLTSPNYNMHAGFSWMGTGSYLPREKAQRLLEQRGNTTLAKDRFKVIDMYFSIWTNQYPYQLVNYLTPLDQKNGWSAEGVNDHWSIVFRNMLDAADRLYSALLANFEVTGRDPFVRQEEQPYVSDRHTRSPCFNDKCLFMTSIDPFPDPKEVVFRGDLRTIEDQSMKFLELDYPTAEFWKTFAYVHAVDNDPLTCWNSYKVPQAGDSFGLRFVKPTVLNRLTVMSSKALTSLEGQMTVLASDQHGFHWIGFGHATRVNQIITELLQSTSSSHTTEYVNDGSNNTPTTTTTTTTTTTPMPPLALTTIATAASNANVIANPAEKTTTVVTTTIKKVVSRHTIYIVSDAPQFIFQDVIALGAIYRNAKVDAGVVQPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MN87</accession>
    <name>A0A9P6MN87_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Beta-N-acetylhexosaminidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_003800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002020">
        <property type="protein sequence ID" value="KAG0008157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MN87"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015929">
        <property type="term" value="F:hexosaminidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038901">
        <property type="entry name" value="HEXDC-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21040">
        <property type="entry name" value="BCDNA.GH04120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21040:SF8">
        <property type="entry name" value="BCDNA.GH04120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0008157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="247" mass="27998" checksum="A3EAAF5C61E553EB" modified="2023-09-13" version="1">MDTDMTISGGFNLLIDLANVPAELQQGISAIANNCPQNNISLRENDEMHEVEFHWLLRFEKDLGLQQGECSVMVDPLIDTSADQKRIAIVVKSLGRILGASRQIQSLDPEKTHSLLCYTEKCCYENLAVMIDCSRGGVLKQSSVFTLMRYCALMGINMMQLYTEDTYEMEGETFFGYLRGGYTRQELVNMDDYADALGIELVPCIQTLGHLGQVLQWPKFHVYRDTNEVLLSNWDETCNLIEKVNEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MND7</accession>
    <name>A0A9P6MND7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Iron-sulfur cluster biogenesis chaperone, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">HSP70_4</name>
        <name evidence="7" type="ORF">BGZ80_003283</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Required for the assembly of iron-sulfur (Fe/S) clusters in mitochondria. Assisted by the DnaJ-like co-chaperone jac1 and the nucleotide exchange factor mge1, it mediates ATP-dependent Fe-S cluster transfer from the scaffold proteins isu1/isu2 to grx5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001860">
        <property type="protein sequence ID" value="KAG0008587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MND7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.34.10:FF:000014">
        <property type="entry name" value="Chaperone protein DnaK HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000020">
        <property type="entry name" value="Chaperone protein HscA homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000545">
        <property type="entry name" value="Endoplasmic reticulum chaperone BiP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000003">
        <property type="entry name" value="Molecular chaperone DnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001413">
        <property type="entry name" value="PRK00290.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="471"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="471"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00059314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00070638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0008587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="493" mass="53229" checksum="875E5B61426E690F" modified="2023-09-13" version="1" fragment="single">VGHAVVTVPAYFNDAQRQATKDAGKIAGLEVLRVINEPTAAALAYGLDKAGDRVVAVYDLGGGTFDISILEIQNGVFEVKSTNGDTALGGEDFDAMLVKYVVEEFKKEQGLDLSNDRMAIQRIREGVEKAKIELSSTLQTDINLPYITADATGPKHINIKLTRSKFEALAKDLINRTIEPCNKAIKDAGVQLNEINEVVLVGGMSRVPKVIETVKQVFGRDPGKSVNPDEAVAIGAAIQGGVLAGSVTDILLLDVTPLSLGIETLGGVFTRLINRNTTIPTKKSQVFSTAADGQTQVQVRVFQGERELVRDNKLLGDFNLHGIAPAPKGVPQIEVSFDIDADGIVNVGAKDKATGRDQSMSIVASSGLSSDEIEKMIKDSELFADSDRKKKEQIEASNQAESIISETEKHMNDFKDQLDSTETQKIKDQIVKLREVLAKGEAVEAEEIKKESTDLQQGSLKLFEMVYKKNAANAASSTSSEGTTVENEEPKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNH4</accession>
    <name>A0A9P6MNH4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003879</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002052">
        <property type="protein sequence ID" value="KAG0008083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNH4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0008083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="193" mass="21749" checksum="CE7C9F5236D9CF21" modified="2023-09-13" version="1">MHTPGEATAHALNLYEIRAHIAQFLSFSDITKAIRVCRQWNDFFHPLLFNAFKIAGNRKNPPLEVLQKYARYIHKLEFDALSAQAPPEYFFLQGCSSLTKLAFRIGNVPQYRVSDLLEENIKIPMELYDPDGDTEEDTEEDTEDSDDPDTGPITTSDASRSSAKEGRNVTSMGVGPLFRFVTCIFSSGDHLNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNM7</accession>
    <name>A0A9P6MNM7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_003365</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001886">
        <property type="protein sequence ID" value="KAG0008503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNM7"/>
    <dbReference type="OrthoDB" id="2390637at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0008503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="467" mass="51524" checksum="878DC45EB9691270" modified="2023-09-13" version="1">MEYAAGGNLKDAIPELDWVEKKRIIVEVATGLAFLHSQGILHRDIKCENILLTEQRQAKLCDFGLAKIMTLSASTGAGNRAVKGTMGYIAPELIHKGPLYSTKSDIYALGVVMKRIGAFSMANNDMPLDYTSLMDQCLHEDPEKRPSANDVARAFEYESAHSIHHSLPASTTILNADEQYSLGKAYCDGFRVDRNYAEAWQRFMFAANMGHVGAQFELGMMYFRGIGTCQSYEDALKWLKQAADQGHNSARNNLAYYYRSGVAGVPSNNIEAAQLFLSAAVEGNILAQINAGRSFEYGQGVDQNHKEAFKWYQKASESGDALAQYHLGTCYYFGQGVAEDYVRASQLWQKAADGGNDQAQYNLGQIFFVGRGVSQDFQKAASLCSKAATQGHMDAQYNLAVSYLKGMGISKDENIAKSWLKSAADQGHIGAQRTLAMMDIGIQERHAMDLPENHNRILLIPTLSKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNW8</accession>
    <name>A0A9P6MNW8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">alpha-galactosidase</fullName>
            <ecNumber evidence="2">3.2.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_003399</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids.</text>
            <dbReference type="EC" id="3.2.1.22"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.22" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010001899">
        <property type="protein sequence ID" value="KAG0008462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNW8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004557">
        <property type="term" value="F:alpha-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14791">
        <property type="entry name" value="GH36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050985">
        <property type="entry name" value="Alpha-glycosidase_related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002252">
        <property type="entry name" value="Glyco_hydro_36"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43053:SF3">
        <property type="entry name" value="ALPHA-GALACTOSIDASE C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43053">
        <property type="entry name" value="GLYCOSIDASE FAMILY 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02065">
        <property type="entry name" value="Melibiase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0008462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="743" mass="84062" checksum="AC44BBDA9D2E125D" modified="2023-09-13" version="1">MHIYDYPGVKGKVHSNLFTVIRDKCFDVTSSIPKDASFQGGEGPDGQNPRPEEVVLCGSLSEDYGYTYFLMDTNKDRFTIMQDCVGKQLRTANDKLVLRTFFAWGSKETLVWDAYADAWKSFYEDRRLIKSSLHQQLSGWTSWYCHYENINEHIILENLGHFSGPGYPQLSGWPAKVFQIDDGYTVVGDWLDCNKEKFPRGMAAIAESIRNKGLLPGLWLAPFLASKKSNIVKEHPEWFIRKPTADDMIEKQHKQFRRQSLCCCCVDFGLHHSASHELMLAHPAFSGAYALDLENPDVQAHLANVFRVVTQEWGFKMLKLDFLFAAALVARNGKTRGQLMWESMQLVRTWAGPETILLGCGVPLGASFMLVDYCRIGCDVGAGWDTMQRHFHDREYISCFNSLTSTLSRWALSSRFFGNDPDVFFIRDWNMGLNATEKRTLMILNHLLGHLVFCSDSFDFSRLNHEQKATLNSFFPWPSTPNITALPHKIVRVLQPLPTQKDVYTIQVQAGENSERTFIVFTNLSSRRQHVHFSAMERIVAKDISENTTSQESTLGVAVYIQTETSQFGLSTAAYTIKPRETCIFLRVIDSNGRLCGPCATLFRPGYTSVALDGMDTSEHVHLLATTGGHVLPTTEIQSFKRHAIRQHELVVVFRPCVFQKTIKVWLAWRRPANDKPIIRDKPDIAKEALMLSSHPSQLHPIRDKPNIAKGALTLNGHPLQLHPELLVGSGICVASCMLHISP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPC3</accession>
    <name>A0A9P6MPC3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_002695</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001675">
        <property type="protein sequence ID" value="KAG0009147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPC3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF120">
        <property type="entry name" value="KRUPPEL-LIKE FACTOR 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="202"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="148"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="148"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="162"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0009147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="273" mass="29715" checksum="E6FE5DF49FF255CA" modified="2023-09-13" version="1">MTSVAPQTPPSKVLPSATNTLIYPSPSLSPVTSFRSVMDSISAENRRISSVKSLMASANPPASPLDALVMALEATAEEIKDQSTHDQIIRSIPAAQEPEEEDPNATVPSSPTFFMKKPPASVPNTVPSLHQLPSLVLPEAAVFPQMSSLSSSHGTQHSVSVNLTPSTHPGQANNQRKMSFSSQGSADSATSVDSNGEHRKTFACSVGNCEKKFSQVAHLRIHERCHTGTRPFIENLGMEMERSERKDMGPHFFRRDGNLEIKKYHDRKGRLGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPD7</accession>
    <name>A0A9P6MPD7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003023</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001778">
        <property type="protein sequence ID" value="KAG0008814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPD7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0008814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="62" mass="6834" checksum="887E3CCBCB902DBC" modified="2023-09-13" version="1" fragment="single">MNKHLSQPASQGMPPGQQPRGEQTSNTKKTPSHGATAQSVFKTDPNQQNQQLSHTETEKLHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPL5</accession>
    <name>A0A9P6MPL5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CPAF-like PDZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_002978</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001763">
        <property type="protein sequence ID" value="KAG0008863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPL5"/>
    <dbReference type="OrthoDB" id="27214at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056186">
        <property type="entry name" value="PDZ_CPAF-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052766">
        <property type="entry name" value="S41A_metabolite_peptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37049">
        <property type="entry name" value="PEPTIDASE S41 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37049:SF4">
        <property type="entry name" value="RHODANESE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23658">
        <property type="entry name" value="PDZ_CPAF_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="45"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="CPAF-like PDZ" evidence="4">
        <location>
            <begin position="334"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF23658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0008863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="843" mass="93588" checksum="859547CC10DB9E06" modified="2023-09-13" version="1">MGSMDSTHPITAVCFSDSMDLIFAGCSNHAVIAWEIRMKRVLFSLTGHSNRISGICLSPDGTQLLSTALDNTVRVWDVDPCTKVDTRLQTTLQGSVAAPLGLETHLSRPAWSNDGSMIGVGTANGEVMIWRKHSIDALSTRFEHMASVNEVDFHPSEPIATLAVVTAVSPTVTTTTSPKSKLTSTSILGLTSTPITKLISTLIPKPKPNPTSTKTNTNLDECGKLGQLKASEITYSDVASCYKSISYDADVASTALEMVYILFNNYYIFRDSALTHDTSRPFKIKPVNITEQLDTIRNTNYTNDFSFHTAITKAINMLHDGHAYYEVDCYDAYTFAQPLALYSPVEDGTQFLRVYKDFSNRGYEECEVLTIDGQPGLSYMQSWSDSVSFSKDAGVRLNYVLASQFYYTVTSQFETNAGLFSQRRDLPENSAIAYELQCKSLNSTIKVQDAWQVFPNTNATFTDTESYLNNVCRADLAKPLHKRSLESGAKPRLKTHIHRRSVFLDAVASNTSAQHHRQVNAASGLPPQAPTRTLVSAEKLGNGEYTAYYLLTSQPDVGIIVVQSHLGQIEEMRTILSYLGEFHRRNVTKLIFDFQSNPGGYIEFSTILVQLIFPLKGDDEFLIPMDLRTDESIQRLSAAVFNYTADYLLYDAWHYADFTNSTRYQSNALFTNAQNMTRNGHRALYSQGTSLMTSIVAIPTPQQFDEYPWTNNSANIRILSDGRCGSACALSSVFFDMNNVTSYAVGGNLNEDLSVFSYPGGSVSNLAEINQMYSIGKVDSPMADLPYSGIVSIPLVEAYFPGSNIPLEYDTERFPATNHIYFDEKNSRSRDVLWSQVAADAWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPM0</accession>
    <name>A0A9P6MPM0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">tRNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_003322</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001871">
        <property type="protein sequence ID" value="KAG0008548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPM0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02799">
        <property type="entry name" value="tRNA_bind_EMAP-II_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002547">
        <property type="entry name" value="tRNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051270">
        <property type="entry name" value="Tyrosine-tRNA_ligase_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11586:SF33">
        <property type="entry name" value="AMINOACYL TRNA SYNTHASE COMPLEX-INTERACTING MULTIFUNCTIONAL PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11586">
        <property type="entry name" value="TRNA-AMINOACYLATION COFACTOR ARC1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01588">
        <property type="entry name" value="tRNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50886">
        <property type="entry name" value="TRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 3" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="TRNA-binding" evidence="5">
        <location>
            <begin position="347"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="53"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="237"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="21"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="53"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="64"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="138"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="238"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="268"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="287"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0008548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="521" mass="55377" checksum="E42B85E60CC471AA" modified="2023-09-13" version="1">MAGSPNSTAGSGANGSGCSNGGNTSTSSSSFLDFAGNGRYQAYNLARFSTFSASLSSPTSTKTQDPAASVQTRSQSVPDATSSVNKAHSNPADAESQSPSSPSLSTTASSTREHHDDKEDDWAVNESYTGHGGNFTPSSSLHDSDSTSSNQHTSSSMIYDDGDSNGESRTALRPSLSSFKSPAAIKASWRQTSDSLPSVILPSTAAVMSQTAPSKAGGLDLSSSTLVQQMLFKERAPHSNNIEGEGCNSSQSDEGNSTTTNSQHANDDFTDWDDEDHIAETKRKNETQITTTSTPELPASSPSLTSMMLDQFNSEKSSSSDLAALPPTKHNKKSNNKAKQEEEEEDHISKLDIRVGVVRSVAVHPDAESLYIEQVDVGDKDGDQPKETRTIVSGLVRHVPKDYLEGRAVIVVGNMKPSKLRGVVSQGMLLCAMEKDSSGEVVKVGLLEPSEGSQPGDKVTIEGYTDEATVPVAVLTPKRKWFEKTQVHFSVKDGVAYYKGSPFKTVQGLVRCKSISEGQIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQ06</accession>
    <name>A0A9P6MQ06_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Splicing factor 3B subunit 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">SF3B3</name>
        <name evidence="10" type="ORF">BGZ80_002192</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the RSE1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001533">
        <property type="protein sequence ID" value="KAG0009650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQ06"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000031">
        <property type="entry name" value="Splicing factor 3b subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000640">
        <property type="entry name" value="Splicing factor 3B subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018846">
        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058543">
        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050358">
        <property type="entry name" value="RSE1/DDB1/CFT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004871">
        <property type="entry name" value="RSE1/DDB1/CPSF1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10644">
        <property type="entry name" value="DNA REPAIR/RNA PROCESSING CPSF FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10433">
        <property type="entry name" value="Beta-prop_RSE1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23726">
        <property type="entry name" value="Beta-prop_RSE1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03178">
        <property type="entry name" value="CPSF_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="RSE1/DDB1/CPSF1 first beta-propeller" evidence="8">
        <location>
            <begin position="13"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 second beta-propeller" evidence="9">
        <location>
            <begin position="449"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 C-terminal" evidence="7">
        <location>
            <begin position="843"/>
            <end position="1160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF10433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF23726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0009650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1194" mass="132519" checksum="FC67A9291893DC8C" modified="2023-09-13" version="1">MFLYNLTLQAPNAINQAILGNFSGTRQQELIVSHISRIELLRPDTTTGKVHSILSHDVFGVIRSLASFRLTGASKDYIVIGSDSGRIVILEYNPNKNVFEKVHQETFGKSGCRRIVPGQYLATDPKGRAVMIGAMEKQKLVYILNRDIAARLTIGSPLEAHKSHTIVHYCTGVDVGFENPIFACLEVDYSEADQDPTGEALKETEKMLTYYELDLGLNHVVRKWSEPVDRKSNMLVAVPGGTDGPSGVLVCSEDYITYKHIGSATHTVPIPRRESPLEIKERGLLIVSGVVHKMRNSFFLLLQSEEGDLYKVTIDYTADTVNEIKIKYFDTVSVASGLCILKSGFLFVASEFGNHHFYQFEKLGDDDDTPEFSSNDFMGRDDDRLDVKVYFKPRPLENLLLVDELTSMAPLTDAKVLNLTDEDTPQIYALCGRGPRSTMRILRHGLEVTEMAVSPLPANPTAVWTTRLTSDDLYDQYIIVSFSNATLVLSIGETVEEVTDTGFLATTPTIAVQQLGQDALLQIYPQGIRHIRANKQVTEWRAPGGRNIVRAATNRQQVVIALTGGELVYFEVDESGNLSESHIRREMSGNVTCLSIQPLPAGRKRVRFLAVGCDDHTVRILSLDASSCLEPLSMQALSAVPESLVMIDMPDQISEGSLTTLYLNIGLQNGVLLRTVLDQTTGQLSDTRTRFLGARAVRLFELNMAGNPSVLALSSRPWLSYQMQSRIHLNPLSYDTLEFAASFTSEQCLEGVVAIAGNELKIFTIEKFGQVFNETAIPLTYTPRRFIVNPVHKSIAIIETDHQTYSTLEKKKKLKELGFEDEEEELDPAIFGHARSTPGKWASLIRILNPATGETTFTLELEQNEAAFSLAVLNFAVESGALFLAVGTAADLTLSPKSLSSGFIHIYKFVNDGMGLELVHKTPVDEVPHALLHFQGRLLAGIGKTLRIYDLGKRKLLRKCENRSIPNSIVTLHNQGGRIVVGDVQESVHYASYIPSDNKIVVFADDKIPRWISCSAMVDYDTIAAGDKFGNFFVNRLPQKISKEIDEDEAGSKSVGKGYLHGAAHKVDLLAHYHVGDVLTSLAKTSFVAGGREMILYTSFLGGIGIFIPFQTKKDIDFFQTLEMHMRNEMPPLAGRDHLSYRGYHVPVKGTVDGDICEQYNLLSGDKKRMIAEELDRTPAEIQKKIEDMRIRAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQ59</accession>
    <name>A0A9P6MQ59_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">M-phase phosphoprotein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">MPHOSPH6</name>
        <name evidence="2" type="ORF">BGZ80_002194</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001533">
        <property type="protein sequence ID" value="KAG0009652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQ59"/>
    <dbReference type="OrthoDB" id="20403at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000460">
        <property type="term" value="P:maturation of 5.8S rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019324">
        <property type="entry name" value="MPP6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13582">
        <property type="entry name" value="M-PHASE PHOSPHOPROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13582:SF0">
        <property type="entry name" value="M-PHASE PHOSPHOPROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10175">
        <property type="entry name" value="MPP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="160"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0009652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="182" mass="20655" checksum="B295E652B74D2217" modified="2023-09-13" version="1">MTEVPHKKALSGKLLTMKFMQRQQERETREKLEKEQVRVITEAHWVLDHKGVELPKPKFQVEYEPSFLQMDSAERSSVGRVSFQKFNEDIEKIASNSAGKQQLERELKRERQGEIGDDEMAEELGGALKAKKTKTSSGSSSPNVSTKPTTNRRVPPKQANNTNSDGSNNGNEKKPVFMKPRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQA6</accession>
    <name>A0A9P6MQA6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_001973</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001471">
        <property type="protein sequence ID" value="KAG0009883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQA6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0009883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="69" mass="8057" checksum="0E53DDC8C5A51C8F" modified="2023-09-13" version="1" fragment="single">AHAEYGKEFFKERKALQGLEKGRRKLHAAVDKVTSKRQRISCEDKNVSLNKKLQSVIPQFDVYEENNDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQG2</accession>
    <name>A0A9P6MQG2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MARVEL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_002693</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001674">
        <property type="protein sequence ID" value="KAG0009150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQG2"/>
    <dbReference type="OrthoDB" id="2437165at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="44"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="79"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="132"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="239"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="260"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0009150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="290" mass="31979" checksum="11FAAFE6E3B9B4F8" modified="2023-09-13" version="1">MKLSPTSITLFLVQIATFLSGLIVAICCGLYLSSYPKSPDAGTISPVACGTFAFAIISTLVTGVLILRQKYGKTLRVIIESAWVIFAIVMWVLASIGGIAFPPNGMTNISCKVLPSGNYTTDPNFIRACQSAFASTAFCIVTALLFIAIALMLFVFSVKRSIYDRKNRKNQVGGHYTLSMTPSQYKRAEKETEEGKNLKGAGEHEEEEEGTEAHQEDGSIAEGHFSENVYRDPVITTLPATLSAPPSNHSPYSATEFNLQQQQLQQQQHNQYQFQQQQDSWNQQPAYAPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQI6</accession>
    <name>A0A9P6MQI6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Amino acid permease/ SLC12A domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_001656</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001384">
        <property type="protein sequence ID" value="KAG0010236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQI6"/>
    <dbReference type="OrthoDB" id="3900342at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015171">
        <property type="term" value="F:amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1740.10:FF:000001">
        <property type="entry name" value="Amino acid permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004840">
        <property type="entry name" value="Amino_acid_permease_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050524">
        <property type="entry name" value="APC_YAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341">
        <property type="entry name" value="AMINO ACID PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341:SF1">
        <property type="entry name" value="GENERAL AMINO-ACID PERMEASE GAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00218">
        <property type="entry name" value="AMINO_ACID_PERMEASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="40"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="70"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="121"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="149"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="176"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="265"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="318"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="363"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="392"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="434"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="477"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="8">
        <location>
            <begin position="39"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0010236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="544" mass="59765" checksum="50D2A00617F331F0" modified="2023-09-13" version="1">MDSKETISAGYQSEKIEMPMEEMTNDESGGLKRDLHLRHMVMIAISGTIGTGLFMTSGKTVATAGPLGALFAYSVIGIWLVFVCQAIGEIATLLPIPGAFTAWGTRVFDEAFSFQLTWSYFLNWALTIPAELSASSLIISYWLPEGSNFPTWIVPVIIILALVVINLLGVRIYGEIEYWFSILKVVTIIIFIICGILVDSGAVGGHVYGVENWHISGAPFKGGFKSFLSVLVSVGFAYGGTELSGVTAAESSNPHKHVPKAVNTVLVRIAFFYILSIFFLACIVPNNDPRLLNADGTVANAPFTIVFLQAGMKGGADYMNAVIFTSVVSAANSDFYVAVRMLLSLSQNGWAPKCVGKTNSRGVPLLAVAITTFFSSIALIMIYAGASQVFNWLVSIIGSMIFMTWCCILFLHFRFRVCWKAQGHTPEDLPYKSWGFPYGHYLASLIAFCCVLASFYLSIDSKPSKDDPDYASARNEWAQGLLGAWFPWVFAVILYFGYKFYNGTKIVNPAEADLDTGRWIPPASVLEEENKPQPKWKKILSMFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQJ2</accession>
    <name>A0A9P6MQJ2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_002352</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001577">
        <property type="protein sequence ID" value="KAG0009477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQJ2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="2">
        <location>
            <begin position="434"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="343"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="457"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="496"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="669"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="346"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="359"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="396"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="556"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="571"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="613"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0009477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="767" mass="86228" checksum="DB6E6A022F01A4AA" modified="2023-09-13" version="1" fragment="single">LQQDHSIDQNLNSYFQNPGSCRETFVTAVTQAEPLEQSIAHGSDHKTFLNTRQITTYSNLSSTFDPPTLQTSKHFSPLCNHRDLDIFSELELGLELEEDNSHLLSASRSHIPAHHPVHPLSFQHHYDHLQLYQQDIDIPNVLTYSTPASELPSLHYLSSFQNTNPCVIHASPLLSPTFEQQPTTQFVEETLNIPNQSLSSRSTASHIDYNCNYPYNNMNNTTMLTSAATLMAPPAGLSFSVQSQQNPAQSMDGIDATLAAFHDLGLDLPQAYGVNPKQENLSSPIYSPISNSSCTSPTTGDLLREQSAAFQTHVSQGYQHEDRKAFDTLNLFTEQELNLDLGNPAVSQSSVTPTPVSFKVEDRSDRNTSTEFEHYPNTLVMDTNTDANPNVDAGLSTSVMTESQSSSKDSTPTSSTPPSPSPPSYDDSMIPVVACASCKRSHIKCDHSRPCQNCRKNPTKAENCRDAVPKPRGRPKGVNKVATSDVHPGFRVANGNPYQYIHDQPEPEQPQFHRQRALSFPHSSSFQEPSPYVLQSQQHHLQPPPLQPHQPQQYPFHHHHHHHYHGHSHQHQQQQQQQQLLLQQQQQQHLNQYHQREIAHTQVRIPPHESRASMPSSTVDFHRQSSGYPSAPYHWSNGDAPPGIPDLKSMYPRRQTVTSSTMLDVHARPSQPIPVQAPPHASNRYFSSSPHAVQTGPMFASLPSHFSSPTRNSPPPLDAYQLHQLQQHRQKLYQQQQLELLQKRNSHSQVQHQIHPHPVMQNHSFFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQM0</accession>
    <name>A0A9P6MQM0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Peptidase A1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_002561</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001636">
        <property type="protein sequence ID" value="KAG0009271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQM0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.70.10:FF:000008">
        <property type="entry name" value="Cathepsin D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF1">
        <property type="entry name" value="ASPARTYL PROTEINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="7 8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0865">Zymogen</keyword>
    <feature type="domain" description="Peptidase A1" evidence="9">
        <location>
            <begin position="65"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="96"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0009271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="232" mass="25005" checksum="0DF7DAD4CBCB7273" modified="2023-09-13" version="1">MLAVVEAVSEGVEIPIILKPNHTRNFHAAMAKASRRYPHLNLGPRLKASRTGRVSLVDFDSDTEYYGSVKIGTPGQTMRLNFDTGSADIWFPSASCKAAACKNHKRFNPAKSRTYRTDGRTWEIEYGDHSGASGILGSDIVNVGGIKVRQTIGLSTLETADFTSEPVEGLFGLAFKADETVKGVKTFMDNAIAARVIAKPVVSAFLPSVRRNGGQHGSYLFGALTGLATLEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQQ1</accession>
    <name>A0A9P6MQQ1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Muscle-specific protein 20</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">MP20</name>
        <name evidence="3" type="ORF">BGZ80_002493</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001618">
        <property type="protein sequence ID" value="KAG0009332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQQ1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015629">
        <property type="term" value="C:actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050606">
        <property type="entry name" value="Calponin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001715">
        <property type="entry name" value="CH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003096">
        <property type="entry name" value="SM22_calponin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47385">
        <property type="entry name" value="CALPONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47385:SF14">
        <property type="entry name" value="TRANSGELIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00307">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00888">
        <property type="entry name" value="SM22CALPONIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00033">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47576">
        <property type="entry name" value="Calponin-homology domain, CH-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50021">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calponin-homology (CH)" evidence="2">
        <location>
            <begin position="23"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0009332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="193" mass="21188" checksum="1AE0E7F68D0B92D0" modified="2023-09-13" version="1">MSAPRKFGIDREIAAKLAAKYDVAREVEARQWMETVVGEPLPLPEFQPALKDGVFLCKLMNVLIPGFVKIKASKMPFVQMENIAKFLQGCEQLGCPKHDLFQTIDLYENKNPGQVVDAIFSLSRHAAKAGCDVPILGPKLADRREVEFSEEVLNAGKHVINTFQYGYSGGANQSGTRNGRREIGGVDPGRGAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQQ4</accession>
    <name>A0A9P6MQQ4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Crinkler effector protein N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_001507</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Host cell</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001343">
        <property type="protein sequence ID" value="KAG0010411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQQ4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043657">
        <property type="term" value="C:host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045379">
        <property type="entry name" value="Crinkler_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20147">
        <property type="entry name" value="Crinkler"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="241"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="Crinkler effector protein N-terminal" evidence="5">
        <location>
            <begin position="21"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="Crinkler effector protein N-terminal" evidence="5">
        <location>
            <begin position="129"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF20147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0010411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="270" mass="30054" checksum="CAE66786A29F1071" modified="2023-09-13" version="1">MARFLNHHSENSIDPVRPKQLKLLCVIEGSSVVFPVNIYSDAVVGDLKDAIKTKKSRDLRSIDADMLTLCKVSISANSKKRIRARDMSAKDILDPSTEISEVFGAEPPKGTIHVQVEKCIDSVKAKQLELLCVGNWKSKALKTFPVYISPEAIVGDLKDVIEAKRSCELHSVDADRLTLYKVSIPNNPKDPAPLRKLILKEVFQMRVAKLDPSMQISELFGTNPSNGTIYIIYRSPVLRTLFFMAFLTCLADTVCIISSGIQIQYSMTPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRH0</accession>
    <name>A0A9P6MRH0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Cation/H+ exchanger transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_001586</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001364">
        <property type="protein sequence ID" value="KAG0010327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRH0"/>
    <dbReference type="OrthoDB" id="2190219at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015385">
        <property type="term" value="F:sodium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120029">
        <property type="term" value="P:proton export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042391">
        <property type="term" value="P:regulation of membrane potential"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036376">
        <property type="term" value="P:sodium ion export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004712">
        <property type="entry name" value="Na+/H+_antiporter_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31382">
        <property type="entry name" value="NA(+)/H(+) ANTIPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31382:SF1">
        <property type="entry name" value="SODIUM ION_PROTON EXCHANGER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="5"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="168"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="209"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="260"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="291"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="328"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="370"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="domain" description="Cation/H+ exchanger transmembrane" evidence="7">
        <location>
            <begin position="6"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="517"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="524"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="538"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="565"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="615"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="651"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="694"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="704"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="718"/>
            <end position="730"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0010327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="730" mass="80000" checksum="492C20B5B2AD55ED" modified="2023-09-13" version="1">MCHFYAVVSTVFGIIIGPYAIGIFDPAGWGEFDAVTLELTRIVIAVQVMAAGVSLPRSYVLKEKLSLFMMLVPLMVLMWLTSALIIWGLIPNIGYLEAMVIATCITPTDPVLSNSVVKGRFAEKHVPPRLRNLLSAESGVNDGMGVPFLFLAYYLLTESSTGVAIGKWFYIAWAYQVTLSIVVGGVVGFSARKLVKGAKSRNLIDKESFLVFSIALALAVVGIVSIMGSDDLLACFIAGNVFAWDDWFSNEIAEAHIQEIIDMLLNLACFVYIGASIPFSSFGDSTLGLSVWRMIVMAIVILIFRRLPFVMALKPFIPALTTYREAAFAGWFGPIGVGAVFYSKVIAMHTDTEHLEHAPQPERLERIRAVTFPVVMFLVFSSVMIHGVTVPLLHLQYKYTRTWSRKREDSNHAVTRLPHINIGDEIVLRPPTINGDGDGSGNEQRTIGYDNQRSIGFDNQRSIGYDHQRSVNQRSFGYGNSVPYGGFGIAGVPDLSRTSQSNNNTVRTLQDVVKEMKDASRGTAANRNLRVANNNNNTDGKSTPNPRDSLTINFNNLPSPREGRTSSSRPMSPVTASSANAVGKESEEISQSLKRDHPVTHASDPRGVSEAQLRSQSDGSNSDNSSSSTAGSKSESAPIRPPHQPISSVVEIHEVEREEDNGIVREVSHDIDVDSTQAEQLLRESGSESSLHIPHPHLPHLSHHSSSQSQGHSSGHHHLTDLFKPQNEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRN0</accession>
    <name>A0A9P6MRN0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_000807</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001178">
        <property type="protein sequence ID" value="KAG0011267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRN0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0011267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="159" mass="18365" checksum="E472F42BC56986D5" modified="2023-09-13" version="1">MRNVGLSLLDIFHDIINCWFRVWKLGGVLLRHYKYPSIRNDFQAMFKEIQPHCDSPRTKSHGLGPSIEGGRDERDENDGHDDGLLGNAEENNWLGMEKPSLEVEAEEVRDFDDERIIEISESDPLELDEGSLPVMDVTPTRGKQAEPQEDYRIEVDWKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRS7</accession>
    <name>A0A9P6MRS7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_000919</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001201">
        <property type="protein sequence ID" value="KAG0011142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRS7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0011142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="287" mass="32682" checksum="37514D1DE13C22A6" modified="2023-09-13" version="1">MDRPLTIQIDGLRLHLLAFKLKELSSVRCTRFPPNVLPSQISSTTGGQDYYLTEIQNVVKTQEDVTSIWGCEPDQIMALGLDPGQASSVVKFAELYGEKLNGGDEDTDLGKSHNVSTTTQPPVAFHNLAVKQNAVYQPTFKYRHWLEDKKMDDKPGDMTESIHFFAVKTPVLKRISKNSTNLQNLSHRNTNYYANISKVLDLAQLATHLQSLSVETLTSGCTFEERLIHTVERHQGLEKLELHNREFAYEPFLRLTRACRRLRSLTIETKFPKLDTQVNFATSRIFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MS59</accession>
    <name>A0A9P6MS59_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Mitochondrial oxaloacetate carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">OAC1_1</name>
        <name evidence="12" type="ORF">BGZ80_000633</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001134">
        <property type="protein sequence ID" value="KAG0011507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MS59"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051508">
        <property type="entry name" value="Mito_Carrier_Antiporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45928">
        <property type="entry name" value="RE38146P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45928:SF1">
        <property type="entry name" value="RE38146P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="28"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="134"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="237"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0011507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="337" mass="36888" checksum="FAD31E1025DF388F" modified="2023-09-13" version="1">MSSPSLQRSDAPLAVSAVPVTTPTIRKPSALYGFMAGGIAACGAVTITNPAEVIKTRLQLQGELMRQAPGTTRIYTSFPQAFVHIAKYEGIRGLQRGLGCAYMYQILMNGTRLGLYDPIKHSIHSLFQTDPAKNNNLVNIVAGGTGGVLSAALASPLFLVKTRLQSYSSHEASRVGFQHYYRHTFDALRHIYKHEGLRGLYRGVDASMMRTGAGSSVQLPLYDVVKQNLIKVGGLENGALCHGLSSLISGFFLCIVMNPFDIISTRMYNQAPDPVTGRGGILYKSPLDCAVKTIRAEGVQALYKGFTAHYFRIGPHTIFTFVFMEQVKALFERLDLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSE5</accession>
    <name>A0A9P6MSE5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytoplasmic dynein 1 intermediate chain 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_000417</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001086">
        <property type="protein sequence ID" value="KAG0011793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSE5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005868">
        <property type="term" value="C:cytoplasmic dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045504">
        <property type="term" value="F:dynein heavy chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045503">
        <property type="term" value="F:dynein light chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010970">
        <property type="term" value="P:transport along microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:001070">
        <property type="entry name" value="Dynein intermediate chain, cytosolic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050687">
        <property type="entry name" value="Dynein_IC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12442:SF22">
        <property type="entry name" value="CYTOPLASMIC DYNEIN 1 INTERMEDIATE CHAIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12442">
        <property type="entry name" value="DYNEIN INTERMEDIATE CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0853">WD repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="17"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="30"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="65"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="82"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0011793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="640" mass="71452" checksum="CCF09DFD966B1A10" modified="2023-09-13" version="1">MERRLELEKKRQKLAELRRAREERSRNALQVSQQLQESPVSAGGAARRDLDDLVASLVGERPATPTLTIDGSSDAGSDKGNSSAIASPPPYSSSSGSQLPHGGLPHVGRLIPEFTSVDAVIFDIPPKERVVYNKEVQTVEGSFEPQGPTEEEIRQQIKEEFAREEQLRLEILEAERLEKEEVLPQEVPELTDEERKAILQSADFVEFMDHSSKIVERAMTEKYDFMKDYTLGLDDETEDLNGNRMRLVSSFHDDRWTKNRSVTDVGWSSKVRVTVRANEMHPELIVSSYNKNPLAVNEPDGIVCVWNIHLADRPEFVFHSQSDVLTVRFSDFHPNLIIGGTYSGQILLWDTRAKTLPVLKTHLSVGGHTHPVYTMDMVGTQNAHNLISVSTDGTMCSWQLDMLAQPQETLALDFPAHPITDEVAVTALGFPDGETNAFWVGTEEGTVYQANRYARAGSQAGINTVYSYKGHFGPITGLHFHPLFGPVDFSDLYLTCSVDWTVKLWRKRTHSKLAIPDNAVVHPLYSFEAADDYVYDVKWSPTHPAIFGTVEGSGKFDVWNLNMDTEVPVMSTIVGAGKALNKLSWSKDGRHAAIGSSDGHVYVYDIGEMATPHAEDWNILQRTVNEMISTQSHGSNQSEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSY6</accession>
    <name>A0A9P6MSY6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ubiquinone biosynthesis protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">COQ9</name>
        <name evidence="11" type="ORF">BGZ80_000375</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Membrane-associated protein that warps the membrane surface to access and bind aromatic isoprenes with high specificity, including ubiquinone (CoQ) isoprene intermediates and presents them directly to Coq7, therefore facilitating the Coq7-mediated hydroxylase step. Participates in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the COQ9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001076">
        <property type="protein sequence ID" value="KAG0011857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSY6"/>
    <dbReference type="OrthoDB" id="619536at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.357.10:FF:000004">
        <property type="entry name" value="Ubiquinone biosynthesis protein COQ9, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.10">
        <property type="entry name" value="Tetracycline Repressor, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013718">
        <property type="entry name" value="COQ9_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012762">
        <property type="entry name" value="Ubiq_biosynth_COQ9"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02396">
        <property type="entry name" value="diverge_rpsU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21427">
        <property type="entry name" value="UBIQUINONE BIOSYNTHESIS PROTEIN COQ9, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21427:SF19">
        <property type="entry name" value="UBIQUINONE BIOSYNTHESIS PROTEIN COQ9, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08511">
        <property type="entry name" value="COQ9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="7 8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="11" id="KW-0830">Ubiquinone</keyword>
    <keyword evidence="4 8" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="domain" description="COQ9 C-terminal" evidence="10">
        <location>
            <begin position="179"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="46"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="48"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0011857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="278" mass="30537" checksum="AC93E7BDB0EDE5BA" modified="2023-09-13" version="1">MATLMRRSCATLLSRNNSMAWCFSRALVTPSVRSFSASTYLRTEEATGANSNSSQDATNQSSNSPAVPSAKGTPEAILKKALTLVPEYGWTTVAISKAAESMGYPAIIHGMFPNGGADLIDYFLQDCLNRLPLELEGRMDGLKTQEKIRLGTLTRLGMVAPYIDRWPEALAIMGQPSNVPMSLNHLGKIVDEIWHLAGDTSADMNWYTKRASLAGIYTTTELYMTTDKTPNYEATQRFLDRRFEDAATLGKATNEVLQIAEFGVKSVFGILNSKGLRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTD6</accession>
    <name>A0A9P6MTD6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transcription initiation factor TFIID subunit 9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">TAF9</name>
        <name evidence="7" type="ORF">BGZ80_011357</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAF9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000902">
        <property type="protein sequence ID" value="KAG0013022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTD6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051123">
        <property type="term" value="P:RNA polymerase II preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07979">
        <property type="entry name" value="HFD_TAF9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003162">
        <property type="entry name" value="TFIID-31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051431">
        <property type="entry name" value="TFIID_subunit_9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48068">
        <property type="entry name" value="TAF9 RNA POLYMERASE II, TATA BOX-BINDING PROTEIN (TBP)-ASSOCIATED FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48068:SF4">
        <property type="entry name" value="TATA-BOX BINDING PROTEIN ASSOCIATED FACTOR 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02291">
        <property type="entry name" value="TFIID-31kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="127"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="140"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="192"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0013022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="220" mass="24786" checksum="C7D2DD2B7F70ED4C" modified="2023-09-13" version="1">MSQTPLPRDAKVISLILQSLSVEDAEQKVIHQLLEFAHRYTTDVFQDALLYSEHAGRTEVGLEDVKLAIQGRVNHSFTSPPPKEFLLELAEEKNKVPLPIIQEKYGIRLPHERHCLTAVNFQLIPELPPPGKQHNLKDTSMSSLSASDAMDISSTPTGLGASLSSNPPSLFKVKEEDDDDDEDMKEATTEEPLSQNQQNMANHDLWKRKRAEDEDNYDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MV40</accession>
    <name>A0A9P6MV40_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Low temperature requirement a</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_010591</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000753">
        <property type="protein sequence ID" value="KAG0014190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MV40"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010640">
        <property type="entry name" value="Low_temperature_requirement_A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42101">
        <property type="entry name" value="CHROMOSOME 16, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42101:SF1">
        <property type="entry name" value="LOW TEMPERATURE REQUIREMENT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06772">
        <property type="entry name" value="LtrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="185"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="217"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="249"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0014190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="283" mass="32439" checksum="3F832640FF8E333F" modified="2023-09-13" version="1">MVASHHRRFLLSDSPFTFEIREIKPARSKTNDEKHPAGPGKYAFKKPVADLSEQLAHEAEKKSATWMELFFDLAFVANITIFTHQHPIINATTMFRYCGWFTIMWWMWLSQTMFDVRFSTDDLLNRIWKLIQLFALAGFAGNGYHFASSNSNGFALSYAVMKLVLVGQYFIVWIHAPNSRCRRPILLYMLANFISFVMWWTSAFLVEALSNQARYSIWFSAIGIEVLATIVLTNNATVTFIGSHLPERLGLFTLIILGESVMGIFMVTDDLVDAPRKLGWDNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVG1</accession>
    <name>A0A9P6MVG1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_010375</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000715">
        <property type="protein sequence ID" value="KAG0014550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVG1"/>
    <dbReference type="OrthoDB" id="2434934at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="379"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="97"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="393"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0014550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="403" mass="42658" checksum="10F869B573EEE702" modified="2023-09-13" version="1">MVSFRGLFLSESQRQVESEARNIGLAHTIRDLITGSSHEAHVDAYQKNKAVKALQKAKPQQVNELITILKAMPDPTVVEFKTVHDRDPSKQHPPTEVPTEAPTETPSEATGEPSPPEKTSDGEEGTTTTAEGGEGRGDGGKVDAEPEVIKAPSSWWAVSFSSLLSSITSTTSTEKPPMTTTTTTVTTFTVTEDKAVSVTEAAVETSKSDPAAPAEAEVVGAGTGAEAGAVEVIATSVDKGTITKTTTSTTTVAEPANADKSVIVSTLNSIKKQIIALGKAPPTNAISAYTFWWGYEIYVPHNCMSQLQRVTNTSQIFFGFLSGAVTGIPGLAALVPLTRIISAWVGLQWAVIQAEDFGNGVILSATWVLPVALAPRSWDHPGNEGNTQPVSAPKRKQKRIKDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVN0</accession>
    <name>A0A9P6MVN0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">TBP-associated factor 6</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Transcription initiation factor TFIID subunit 6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_010004</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAF6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000652">
        <property type="protein sequence ID" value="KAG0015173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVN0"/>
    <dbReference type="OrthoDB" id="361039at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046695">
        <property type="term" value="C:SLIK (SAGA-like) complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051123">
        <property type="term" value="P:RNA polymerase II preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22931">
        <property type="entry name" value="HFD_TAF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08050">
        <property type="entry name" value="TAF6C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000033">
        <property type="entry name" value="Transcription initiation factor TFIID complex subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.770:FF:000001">
        <property type="entry name" value="Transcription initiation factor TFIID subunit 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.770">
        <property type="entry name" value="TAF6, C-terminal HEAT repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037796">
        <property type="entry name" value="TAF6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011442">
        <property type="entry name" value="TAF6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046344">
        <property type="entry name" value="TAF6_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004823">
        <property type="entry name" value="TAF_TATA-bd_Histone-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10221">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10221:SF9">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02969">
        <property type="entry name" value="TAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07571">
        <property type="entry name" value="TAF6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00803">
        <property type="entry name" value="TAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TATA box binding protein associated factor (TAF) histone-like fold" evidence="9">
        <location>
            <begin position="11"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="167"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="178"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00076308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00093655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0015173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="501" mass="55159" checksum="D14EE1411861D80B" modified="2023-09-13" version="1">MKNTITVTRGQLYKDIAESVGIPNLKDDVASSLAQDVEYRIHEIVQEAVKFMRHGKRTKLSVDDINNALRVRNVEPLYGFSSADPTRFRRTTAGTGATGTTEIFFLEDEELDFETILSAPLPKVPLDVTYTAHWLAIEGVQPAIPQNPTPTDAKTDLLHKRIKLDPSTQPVIPGIKPGSSSNANNNNNANGGNSNSGDAEIKPLVKHVLSKELQMYYERITSAVLSQDEVLRATGISSLQNDPGLHQLLPYFVQLVAEKVTQNTRNLPVLVSMMAMVRALLDNDNLFIEPYLHQLMPTILTCVVGKRLGESPAQEDHWSLRSTATDIILMICEKYGSSYHTLQPRVTRTLLRAFLDPEKPLTTHYGAILGLSRMGNEVFKTLVVPNLKTYSSVIEPELLGSGLDQDDDNFMEVENDHLEGSASAIKRSEAVHCLDALLIGLRALIKSEAIKAKATAKTVPTIEDVREPLTQAIGELLARAVLKEDGIDQNLLGIVVVIESC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MW11</accession>
    <name>A0A9P6MW11_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Retinol dehydrogenase 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">RDH5_2</name>
        <name evidence="2" type="ORF">BGZ80_010124</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000672">
        <property type="protein sequence ID" value="KAG0014976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MW11"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008202">
        <property type="term" value="P:steroid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43313:SF1">
        <property type="entry name" value="3BETA-HYDROXYSTEROID DEHYDROGENASE DHS-16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43313">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0014976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="321" mass="36066" checksum="A274E1544B42ACCF" modified="2023-09-13" version="1">MALTNPTDLVVVITGCDTGFGAEIADEMCQREGFTIYPTCLTDEGFEKYKAMKSSRIRPVKLDVTNQEDVNRFRALVEAECPQGVYCVFNNAEDVFQKIMDVNYMGVVRITKALIPSLRTYAKSRHSTKDKDLPSARILTITSIASRCNPPGHAGYSASKHAVESFLDTLRLEMIPWEINVSMIEPFYAKTPMIFNTPGFQDQVWKAAGPNIQNMYGTGFIGSVAKYTRLLYGFSMPSKWVVDTSVDAVTKKNGARRARILIGFWWASTVLRLQEWSPSWMVDYLTGCLMKYLGIYPSDPFLIKDSESAKESVSTKTVKNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWN8</accession>
    <name>A0A9P6MWN8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_009691</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000603">
        <property type="protein sequence ID" value="KAG0015700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWN8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="415"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0015700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="680" mass="74750" checksum="C949A682C3F8C3B5" modified="2023-09-13" version="1">MSNSQEETHIVVDLGSSLSIPHEDTRDAKGLEVEDVSYDSTHCEQSQQDDIWLLSTLSFHLDLLTAGSLFLLPSILPFLASTLTSYITDNASPQSIPSPTTTTSPLSYDITSPTSAASDIWNWQTTWVPLLPCIGAVAPLSLLKVMTMVEESSFQCPFQRWRRSKSGSNSQRNPICVSCARDATRVIRQQQYHRHGTMFGPTVHVIKRAWQAFKREPSGYQPLSLDSPLSEGFSDNDNNICGVEEESECDDETIMVESTDGAPCTCKKSYYYMRQQPSVLPRPRSILRAGLIVWTVLMGLSSILGLNTVRPTSAVFNDTNATADGIDLQTWESMSTSTLRQGGFIAVEESRFPSDGAINYDDGEHDILSVVAAMQEQERSPASLEELNQPLPINQHELFATIKTSIIIVNKERPHDASASLPQIKEEEEEENTADDIKDFMEPDSLDALIMDPDDAILFHDFLAQLKAEDQATKAPEESNLEAYSEKQKRVIKATDDHMIPSMLENDIPCGTKTVPMRPTPTIDLPDFVQKILDSAGPGRLGQREGGQTFKYLAGWTELMILAVATCFGTIMAGLAQARVLSSQLSESSEASVTSPQKLEGCASTRTLPSCLAISGSALGLTLLMIFSECWDVPSVYFSGIGIAGIILIDAWIPDMSLQVECVNEEANYYGMDQEKALIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXH7</accession>
    <name>A0A9P6MXH7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Importin subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">SRP1_3</name>
        <name evidence="10" type="ORF">BGZ80_009262</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the importin alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000539">
        <property type="protein sequence ID" value="KAG0016368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXH7"/>
    <dbReference type="OrthoDB" id="29145at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061608">
        <property type="term" value="F:nuclear import signal receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000021">
        <property type="entry name" value="Importin subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.690">
        <property type="entry name" value="Importin-alpha, importin-beta-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032413">
        <property type="entry name" value="Arm_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002652">
        <property type="entry name" value="Importin-a_IBB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036975">
        <property type="entry name" value="Importin-a_IBB_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024931">
        <property type="entry name" value="Importin_alpha"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23316">
        <property type="entry name" value="IMPORTIN ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00514">
        <property type="entry name" value="Arm"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16186">
        <property type="entry name" value="Arm_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01749">
        <property type="entry name" value="IBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005673">
        <property type="entry name" value="Importin_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00185">
        <property type="entry name" value="ARM"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50176">
        <property type="entry name" value="ARM_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51214">
        <property type="entry name" value="IBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5 7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="IBB" evidence="9">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="6">
        <location>
            <begin position="114"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="6">
        <location>
            <begin position="156"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="6">
        <location>
            <begin position="325"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR005673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0016368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="533" mass="58897" checksum="EE84A936DF7FBEEC" modified="2023-09-13" version="1">MDKVPEHRAQNFKAKNAFKPEELRRNRNELNVELRKQKREENLSKRRNLAIAAETDSEDEGISAADREFHERLPAMIQGVMSENAEEQLGAITSFRKLLSKVRNPPIDEVIRCGVVPRFVEFLRSPHAVVQFEAAWALTNIASGTSAQTQYVIEAGAILEFVELLSSPVDDVKEQAVWALGNIAGDSPRCRDIVLCENALAPLLTLLHENINLTMLRNATWTLSNFCRGKNPPPDWNLITPALSILAKLIHSTDDDVLIDACWAVSYLSDGTNEKIQAVIESGVCRRIVELLTHHMASVQTPALRTVGNIVTGDDVQTQVIINYGALQAMLALLASPKDNIRKEACWTISNITAGNNNQIQSVIDANLIPPLIAILQNADFKSKKEACWAISNATSGGLNKPDQIRYLVSQGCIKPLCDILLCMDSKIIHIALDGLENILKVGEMDKEHMNGVNQFSVFIEDCGGMEKIHNLQAHDNADIYRKAYDLIDKYFAEDDDEETGLVPQVDSQTGAFAFQATGAPQGGFNFDPSGMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXX4</accession>
    <name>A0A9P6MXX4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">choline-phosphate cytidylyltransferase</fullName>
            <ecNumber evidence="8">2.7.7.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_007670</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytidylyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.15" evidence="8"/>
    <dbReference type="EMBL" id="JAAAID010000397">
        <property type="protein sequence ID" value="KAG0017996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXX4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004105">
        <property type="term" value="F:choline-phosphate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031210">
        <property type="term" value="F:phosphatidylcholine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02174">
        <property type="entry name" value="CCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041723">
        <property type="entry name" value="CCT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045049">
        <property type="entry name" value="Pcy1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10739:SF13">
        <property type="entry name" value="CHOLINE-PHOSPHATE CYTIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10739">
        <property type="entry name" value="CYTIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="6" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="7" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cytidyltransferase-like" evidence="10">
        <location>
            <begin position="118"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="334"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="8"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="73"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="89"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="336"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="370"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00026101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0017996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="387" mass="43222" checksum="39369BE5BD542C45" modified="2023-09-13" version="1">MTPKHRSTTATSASASAPLSLSAPAPASSTSTTSKQSCISQSDSIDIQNQHDQEDQAQDMDQEKTKEIEEDTSPSSSNSSTKSNDNERVSGSSGPSTPMYSYPINPPPEGRLVRIYRDGIYDLFHFGHAKALEKAKKSFPDVYLIVGVCDDTLTHNHKGKTVMTDKERYESVRHCKWVDEVVESAPWVIDQAFLDRHKIDYVAHDDNPYKSVDSDDVYAFVKNKGQFLPTQRTEGVSTSDLITRIVKDYDQYLRRNLERGVSAKELGIGFFKEHEVKLKKSAKDIQDSIRQNWHGTRDDLLQVLAAWEDKSHEFVKETFGVDSVVNKIFSKRHRPGTSSRSVIESVNTGSSGVSSDEEGPLSPTRLASPDSREVFDSEEKGIPDNKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MY67</accession>
    <name>A0A9P6MY67_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_007487</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000385">
        <property type="protein sequence ID" value="KAG0018162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MY67"/>
    <dbReference type="OrthoDB" id="10250354at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051434">
        <property type="entry name" value="DnaJ_C_subfamily_member5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019396">
        <property type="entry name" value="TM_Fragile-X-F-assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44027">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 5 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44027:SF7">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 5 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10269">
        <property type="entry name" value="Tmemb_185A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0564">Palmitate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="95"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="129"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="192"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="224"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="264"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="298"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="338"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="372"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="8">
        <location>
            <begin position="7"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="418"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="433"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0018162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="449" mass="50220" checksum="36996A97252EAF97" modified="2023-09-13" version="1">MDRNTVHLYEALEVPKTATQDEIKKAYRRLALRYHPDKVNPAEVPDHETKFREIAAAYEVLSDPKKRQVYDKYGMMGVQMAGTDIGAQLIEIESFLCTIFVALSVLLALAIIFFSFLAVRLDNKVNWNYYVVFIPVWILDFILLAMVVIQATQPVNIDEEDDQEENEDGDTTPMAQEERKANKLKGLKRQRIMGSGIALIIILLVIAFQVLIVKKANDPSSISGPAVFTPYFILEAILVIYAIIKLTVRLRSEAYADVPLKKKLIVVFEGLWWKVIRLALAILIMYRIDDRITCSWGVVFIPLYLVGLKYLIQIIASYRSYSKMDNPEMKQQGQALSIVLGVVFVVVGSISYVLIGLLAAKLDGHSYSIARVLVPVFVTLGILLCCSGCCLPCLLLGNADMDDEMMEREGAEVRMVSPNLRIENGSAAPPSPSSSRRFGRRSANASSQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZ24</accession>
    <name>A0A9P6MZ24_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Phosphoenolpyruvate synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_007769</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PEP-utilizing enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000403">
        <property type="protein sequence ID" value="KAG0017924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.10">
        <property type="entry name" value="Phosphohistidine domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008279">
        <property type="entry name" value="PEP-util_enz_mobile_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051549">
        <property type="entry name" value="PEP_Utilizing_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036637">
        <property type="entry name" value="Phosphohistidine_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002192">
        <property type="entry name" value="PPDK_AMP/ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43615">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43615:SF1">
        <property type="entry name" value="PPDK_N DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00391">
        <property type="entry name" value="PEP-utilizers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01326">
        <property type="entry name" value="PPDK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52009">
        <property type="entry name" value="Phosphohistidine domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="4">
        <location>
            <begin position="88"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="domain" description="Pyruvate phosphate dikinase AMP/ATP-binding" evidence="5">
        <location>
            <begin position="753"/>
            <end position="1048"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilising enzyme mobile" evidence="3">
        <location>
            <begin position="1693"/>
            <end position="1762"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1065"/>
            <end position="1086"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1065"/>
            <end position="1085"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0017924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1783" mass="195696" checksum="12A973E4C11833EE" modified="2023-09-13" version="1">MSPEITQAVAASYSSTESAKAIAVSQLHDFLSNGFPDIFRWSLHRPPTAEERNGNLCSLFNAMFTHLRNTLPTNEPSPDCFIFTEPGKPSVTFDELCSRISHLAQILAQDGTSKSRSGTKPLGQGDKVLILSSLGVDFFVGSIACLSLGATLILLDPFMERAKMNVCIESVLPITHIVTNMKLTIFKKWILSKAVPALKKIPNIVEIPVNVDKKILAMAPKTIPVTSLPGDTTALLSFTTGSTGNPKPIRRSHDYLRAQTIAVFCQREIKASAAEFPGEAGTNAPTAPHKPVKSVTNLPVFIFGQIMLGYTTLIPDNFNPAGVNPAPLVQAMIRHNVQVAFGSPAFFIRLLEHLEQVGGVDQHGKFLNPLPVRVLCLGGAPVFSSELDIMRRGVKGAAFIFYGASEAEPISKIRVEERILLEASSSNTPTASQNTKTSNRISRLDFSSLETDSGFEGGNMNAICVGHVNLDGGFALTAIAPLDAEKADGKQFLELGHIGEIVVSGPHVHITTTSDDDRIIHELPSETNGEKSRVWLRTGDCGYLDSANRLWLVGRASWVVKEIADEDGLHSLRYWPIAIERSVLETFGSSHGVTYAVFMPSGTTGKPALFVEVPNGLPLAARSLILEHLQETFDVPVDELHVFRKLPRDKRHASKINTMALSKMIKNKKATDKIVIQRNDIAGTLNDNLRRGITVTSLKQSASLPDVAAHNTLTNAVTGDTIHSEQRFKFSNPEQNHFLFAWHPAPLLAQYGGGKAKNMATLTNLVCRIPGVRATVPAWFCVSTEAFKAFLSEHNLDSQIAPHVTTSEGLESFHTSLTQKIMAAPLSSSMAQELAALIEYLSSTSTSSSTAKPYFAVRSSGADEDSVSHSFAGQFDSFLYRQSIDEIIDALKRCWLSAFAPRVMSHRLACGLPINNVRMGVVVQIMVNSECAGVAFSRHPLNPISANASLVEAVEHGYNGNVKETIVPKPKMWVRNGGDPDGTNATGLVSVEVPESKASAAALTHDRARAVGATVTGLESLIGMPVDFEWAYQEEDPMLYCLQVRPIVNLPPSSFFIALDKKTPSSAPSESNMSNSSSDSSISSNEAKNKNDLVDLSSIATRALDALAAPQGMNVTLWDNSNIVESYSGVTTPLTFSFASYNYRIVYETMLTFLGTPTKYIQDNEDAFINLLGYVRGNVYYNLMNWYRLLLLAPLGKFSDPKHMETMMGVKQGQEGNADMEKEFKKILEARPKFTAWHRTRLLLKYISAYNNIDRIVNDFFTNFNAFYNSGRVMDFKTMSLEEIAIYYKRNASTLLRDWKAPVINDLLVMGFFGTLKSFIAKHLVESKAAPATPGAAAPTAEETKAAAADAAAVDSLQNDLLCGEDVESAKPTKMLMEIAKSIDNTIEYPDLGTWFTGHKDAILKAVKPEGGQWILRSTILKLSFVRANELLTELNVIEPGKEQPPVQVVADVLAMILEFLDSYGFRCINELKLEEKDLNDDPAFVIDAIAGYVRTKAYEVEDLDKREHQIRAAAEALVHQKLKGAQLKIFMWLLRNTRRVVKHRENLRFARSKVFGVMRRIFRGMGHQLVKLGALEAEQDVFYLTTEELLSYVDGRGVSRDLKALTKIRKNEFDGYVADANAPPERFITRGAAGVYMWYPHILADLDLLKDAEDSNGPPEPGVLKGVSCCPGVVEGVVRVVKDISETRDLNNEILVTARTDPGWVPLYPMCSGLLIERGSLLSHSAVVARELGLPTIVGISGGLMKRLKTGMRIKMDAGKGRVYILDELEALEKENENAHTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0B1</accession>
    <name>A0A9P6N0B1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_004160</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000215">
        <property type="protein sequence ID" value="KAG0020459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0B1"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24296">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="489"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0020459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="543" mass="61314" checksum="F2F616A9ABD8F9FD" modified="2023-09-13" version="1">MSSPVTALVTVLKERILSPKSRSQKAGLFALLGLLYLIAKYPNRAYGTRARPDLDAIAWHGVPILGNTLSVLWNRHKFLDLIIFFFEQTKLPVMSTTILGLGRIIGVNSPEMIEHILKNNFENYEKGPVINENLRQALGNGIFNSDGALWKFHRKTASHVFSTKIYRSLIDGPFQTHTGQLIGILDKAAADGTAVDLHALFLRLTLDTFAELSFGLDINSLGKEGKDEFGAAFDYAVVQTDARFMNPFWRITEKFTPGYFKMKRAVATVDNYAYNAIDGRRKETAEETRERQGPSGREDLLDLFMKYRDENGRALNDVELRDVFISFIIAGRDTTAQALSWMYYEVMKNPVVEENIWKEIEQVGTKPNYEMLMKDMRYTNAVFLEALRLYPPVPRNLKEAVNDDVLPNGTKVQAGDFILFSTYSIGRNVSVWGPQARDFMPERWLEGSAEAVEKGSLSNHTFTADHVHAKLRKESQFKFSSFNAGPRICLGQTFATLEALTVINMLSSRFKFTLAPGQAPAVEKTSLTLPMKRPLLVNVTRRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0D4</accession>
    <name>A0A9P6N0D4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Peptidase A1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_005890</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000290">
        <property type="protein sequence ID" value="KAG0019384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0D4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF51">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040434893" description="Peptidase A1 domain-containing protein" evidence="5">
        <location>
            <begin position="18"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="6">
        <location>
            <begin position="69"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="87"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0019384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="362" mass="37877" checksum="D81686584C7AC915" modified="2023-09-13" version="1">MVKVLPILLLSIACTFAAPAPKQLVKLPLKAPHKRVALHEAHSKDLARWAHLSADSTFSIPAINADVSYLITVGLGTPAQDVDLIFDTGSSDLWVQSANYDPSQSSTSSDLGETFSIEYGSGSTSGEEYTDQVTIGGFTFTQEFGVASEASGFDGTQGLVGFGPDDLSAITSNGENIPTPTDNLYSSGQISSDVIGVYFQPITDGGSQETNGEVTFGGVDSTNSITYGTTKVSSATHGIVDTGTTLILLSSNDVTALYKNIQGAALDNNTGLYTIPSSQVSKLKNITFTIGGTAFTLTPSQYLVPANQVANMGGNSGTTYSWIGSLGDNESGLAFILGQKFLENYYSVYDTTNNRVGLATAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0S3</accession>
    <name>A0A9P6N0S3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="3">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_003280</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="3"/>
    <dbReference type="EMBL" id="JAAAID010000186">
        <property type="protein sequence ID" value="KAG0020970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0S3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2230.10">
        <property type="entry name" value="DUSP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035927">
        <property type="entry name" value="DUSP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF722">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143791">
        <property type="entry name" value="DUSP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="10">
        <location>
            <begin position="584"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="530"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="213"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0020970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="689" mass="78384" checksum="8BB206CD347E6365" modified="2023-09-13" version="1">MGQDQWEKEDALDRYFGMITIKPNPVLLKRPVDTPAGMKNLGATCYANSLLQVWFHDLVFRDAIYRCRFSGDADNSMFQGHYSYNTTCKNCLRTSARDCTFYELMLNIKDNCTLMDCLEEFVEPEELVGADRNNKWFVLNDEEVTEFHGTRFDPEDYSEVASKAKTKKAAVKGDGEAEKLLNTLSSRNAYMLTYVRRASELPIRPSSPPNETLEIVQQDNAKLEIEIKEYEEYKNKVKDDFDRLRDKRRELYRCWGVNSDEDNGYYVSSEALAKYIQSDSDLSQTLDNSSIACEHGKLCPSAVARSKRIRDELTNGCSLLALRLDKLYTLMHRRDIDEFERKAKGKRSPPAVWVSKAWLIDWLKVSPRFHPENGTTVDDPSPLSKAYITDVLCQHSSLSIDKSRRKQINKAASLYDILALFELSGMVMRGARFRHMEPGKNYYAVSKEGFMKQWLDFVKRPTVNVQPTAIDNSSLLCRHDRFVFDLNNEIDMENDNDLFVVNEEEWATLQAMILDFSSTTLVIRVYTPRKATGENGGTTGGQSSTESLEVVSKVPPSNKPSKAKRKQAPPVPEGEFSARRSKRVKAVEKSYKEIKVLVSKYDTVMDLKLKIMQKTEIVPLYQKLLHEKVELENNDSTIADLKIPPNAILDLIAFDQSADDLDLSSLQDVVSTPGDEGGFGGTGLAEDWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1A5</accession>
    <name>A0A9P6N1A5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Trafficking protein particle complex subunit BET3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">BET3</name>
        <name evidence="9" type="ORF">BGZ80_003340</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 8">Golgi apparatus</location>
            <location evidence="1 8">cis-Golgi network</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the TRAPP small subunits family. BET3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000188">
        <property type="protein sequence ID" value="KAG0020924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1A5"/>
    <dbReference type="OrthoDB" id="10262857at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030008">
        <property type="term" value="C:TRAPP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048193">
        <property type="term" value="P:Golgi vesicle transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016236">
        <property type="term" value="P:macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd14942">
        <property type="entry name" value="TRAPPC3_bet3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1380.20:FF:000001">
        <property type="entry name" value="Trafficking protein particle complex subunit BET3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.20">
        <property type="entry name" value="Trafficking protein particle complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016721">
        <property type="entry name" value="Bet3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024096">
        <property type="entry name" value="NO_sig/Golgi_transp_ligand-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007194">
        <property type="entry name" value="TRAPP_component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13048">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04051">
        <property type="entry name" value="TRAPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018293">
        <property type="entry name" value="TRAPP_I_complex_Bet3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111126">
        <property type="entry name" value="Ligand-binding domain in the NO signalling and Golgi transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 8" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="7 8" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR018293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0020924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="188" mass="21486" checksum="F170428E1D984C55" modified="2023-09-13" version="1">MAKQYKTIGDEIWKNKVEKINAELFTLTYGSIVAQLVKDYEDFGEVNKQLEKMGYNIGTRLIEDFLARSNVGRCQDFRETAEMISKVGFKMFLNITPAVTNISADGREFSLVLEENPLAEFVELPDQAAVEDFWYSNILCGVLRGSLEMVQMQVDSFFVTDTLRGDEITEIRVKLIRYLEEEVPAGED</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1I5</accession>
    <name>A0A9P6N1I5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_001900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000145">
        <property type="protein sequence ID" value="KAG0021689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1I5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="49"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="89"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="148"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="505"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="18"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0021689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="551" mass="61351" checksum="2F624B8C540C5BBE" modified="2023-09-13" version="1">MLGGPRKLTDDKFTGADNNYNNSRNYNNSHNYHKTNEKSNLLHMKIESLGVRLLLFTVIWIITAAAQLVGLSSVVTGQTGESDILKQRVAYWATACAILYGACLFFVAQWFTKDLVWHWHTNHVRELWGLQPSLASLSIGLIHIRMPLMIVFTLCLTLMSLTSMVTNFWLTGSTQIVQHIEQGPPVNYSLLGLPTWGEDFRFTSTGGIAFESFVSQSGASAAGLVQLTPYDNKYIWSPFLNSSTAASINVTDVLSVAIEPKCTLLSAADLGIAYNQTLDWGLDLNLTISTYNVTIPGVRGRFYYWGVEANPYFLGPNNTAPMGVNVYNVMARQTMDYGAPSFMFANLGTPSYIYITNCTVEVQWWNVSGTISSLTPQRLDISSAIRTDEKIAYDNVYWLQYITDTYQAGLSSYTQGAQGMYDSISYNLKSPLWMWMMGESYRPTNTTGTLLNTIIHPNITNAAWVETKLSEIVGGTLTTNTVAVAPTYYIGREVIYTSIIIAATYRIIVGLAVQSALLWIPIIIYISKRKARIFYGDDIAHLLNKDSVLDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1S6</accession>
    <name>A0A9P6N1S6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_001899</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000145">
        <property type="protein sequence ID" value="KAG0021688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1S6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16464">
        <property type="entry name" value="RING-H2_Pirh2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039512">
        <property type="entry name" value="RCHY1_zinc-ribbon"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008913">
        <property type="entry name" value="Znf_CHY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037274">
        <property type="entry name" value="Znf_CHY_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017921">
        <property type="entry name" value="Znf_CTCHY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037275">
        <property type="entry name" value="Znf_CTCHY_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21319:SF0">
        <property type="entry name" value="AND RING FINGER DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G08900)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21319">
        <property type="entry name" value="RING FINGER AND CHY ZINC FINGER DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05495">
        <property type="entry name" value="zf-CHY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14599">
        <property type="entry name" value="zinc_ribbon_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161219">
        <property type="entry name" value="CHY zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161245">
        <property type="entry name" value="Zinc hairpin stack"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51266">
        <property type="entry name" value="ZF_CHY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51270">
        <property type="entry name" value="ZF_CTCHY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CHY-type" evidence="7">
        <location>
            <begin position="288"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="domain" description="CTCHY-type" evidence="8">
        <location>
            <begin position="357"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="424"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="146"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="257"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="537"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="38"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="59"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="181"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="199"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="569"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="594"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="626"/>
            <end position="635"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0021688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="635" mass="69692" checksum="113F4FC3D419F810" modified="2023-09-13" version="1">MSSPTPYNSTANSPHAELPEIAAGNSTDSAEAGYLSQESERAPSNESHVVSDHIPEQTPESDENQGYSDEYESAGEDENYDLGDEEDSDSDGEVYVVIEGDIDMGAAANHIGRTSTSTSSDEHDQGQELDMQDNEEFVMEIDPATGQRRATTVSTTTPRARSSSLASRLRRQHRRMTTSVRFTATARPAATRPPGSGLSRPTTGFSAPTSTRATAAVPLIDENAQSELRKKIMEIQRNPDIGFGEKASMIQRLMSPNWHDTRKAPDQQSGGDPGVTTEEDLKTTYHDQERGVLGCKHYKRGCKLKANCCGKWFNCRFCHDDVCDHSIVRNETKMMLCMHCKVIQPAAQNCSSCQAQMAHYFCDICKLWDDDSQKPIYHCDDCGICRIGNGLNQDFFHCKKCNICMHINLKDNHKCIERNLECDCPICGEYMFTSTTTVIFMPCGHSIHAKCHGEYVKTSYQCPTCWKALADMSRYYQKIDSILAEQIMPPEYANVFSTVLCNDCEVKSQVPYHFLYHKCDKCKGYNTKVLETFRRDTEDSIQPNENAAAASAAGTVPENNISGAGGAAAGQPSPSSPSSSSPSLSRSERFGDSGSATTATIVQLSEIPRTQFLDGNASEDMGFNSMAGSSGNSAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N244</accession>
    <name>A0A9P6N244_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">beta-N-acetylhexosaminidase</fullName>
            <ecNumber evidence="3">3.2.1.52</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BGZ80_003219</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.</text>
            <dbReference type="EC" id="3.2.1.52"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.52" evidence="3"/>
    <dbReference type="EMBL" id="JAAAID010000184">
        <property type="protein sequence ID" value="KAG0021014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N244"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016231">
        <property type="term" value="F:beta-N-acetylglucosaminidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030203">
        <property type="term" value="P:glycosaminoglycan metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.379.10">
        <property type="entry name" value="Chitobiase/beta-hexosaminidase domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025705">
        <property type="entry name" value="Beta_hexosaminidase_sua/sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015883">
        <property type="entry name" value="Glyco_hydro_20_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029018">
        <property type="entry name" value="Hex-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029019">
        <property type="entry name" value="HEX_eukaryotic_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22600">
        <property type="entry name" value="BETA-HEXOSAMINIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22600:SF26">
        <property type="entry name" value="BETA-N-ACETYLHEXOSAMINIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00728">
        <property type="entry name" value="Glyco_hydro_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14845">
        <property type="entry name" value="Glycohydro_20b2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001093">
        <property type="entry name" value="B-hxosamndse_ab_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00738">
        <property type="entry name" value="GLHYDRLASE20"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55545">
        <property type="entry name" value="beta-N-acetylhexosaminidase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040275960" description="beta-N-acetylhexosaminidase" evidence="9">
        <location>
            <begin position="21"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-hexosaminidase eukaryotic type N-terminal" evidence="11">
        <location>
            <begin position="25"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 20 catalytic" evidence="10">
        <location>
            <begin position="181"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="345"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001093-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF14845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0021014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="566" mass="63942" checksum="7484FEEBE6428EF5" modified="2023-09-13" version="1" fragment="single">MRISIAAALGLTAVTVISNAVKVNPLPAPVTAIWGNTGPIKVANNFRIVGPKHEILSKAFARTASLIKEERWIPQTWEQPVGEFLPFPTLEKGTFESFTSSNRDVLRTIDVQVENIEADLQMGVDESYILDITVAGKGTINAKTIWGALHGLNTLTQIIIDDGNHGLQIEEPVHIEDAPKYTHRGILYDTARNFYPLKSLMKQIDALSWAKLNIFHWHITDAQSWPLEIKKHPQMTKGAYSPREIYTQRDIMNLIEYGRERGVRVIPEIDMPGHSTSGWLQVDEKAVTCYDSWWGNDGWTHHTAVEPNPGQLDISYDGTYTLIKDVYSEAANLFTDNIFHVGSDELQTYCFNYSASAMNWFKERPDSTYADFAQYYLDKALPIYMDKPERRLMMWEDIVLSPDMPARNVPKDIIMQSWSSGTDNIKKLAERGYDVVVSSADFFYLDCGNGGWVTNDPRYNVNEPPVLPKVIKDAFANNPSDYYLASNNYLGSGASWCDPYKTWQRIYAYDFTEGLTGEEAKKVIGGEAALWSEQADASVVENKVWPRAAALAELFWSGNRNKEGYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N284</accession>
    <name>A0A9P6N284_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001523</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000135">
        <property type="protein sequence ID" value="KAG0021881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N284"/>
    <dbReference type="OrthoDB" id="5596992at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="14"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="170"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0021881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="218" mass="24262" checksum="C101ABABB8135F4E" modified="2023-09-13" version="1">MAPPPRTRTRGKKLPPGAGKTAAAKKANAIEKSPHVLEDPDNESVCMEVDQETADAKAWINENVEQEVARIRSTGTNIEPLSVKNFGIVVDLSRKKATAINRIEINSSFDFKNVQQIMVSPGIVYPHKENFEYVNVLLFGENTGAPMLVPYLYDTKFKTQEPLEGESEDTSTSSQSASSAGSADQRPWINVKNNLTEWLLVNAQHQRARCHIDEFHDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2V4</accession>
    <name>A0A9P6N2V4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Inorganic phosphate transporter pho84</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">PHO84_8</name>
        <name evidence="9" type="ORF">BGZ80_011730</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000098">
        <property type="protein sequence ID" value="KAG0022584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N2V4"/>
    <dbReference type="OrthoDB" id="433512at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17364">
        <property type="entry name" value="MFS_PhT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004738">
        <property type="entry name" value="Phos_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00887">
        <property type="entry name" value="2A0109"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24064">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 22 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="76"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="171"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="208"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="297"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="343"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="375"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="398"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="473"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="35"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0022584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="517" mass="56500" checksum="5E26400901FCF5D9" modified="2023-09-13" version="1">MSQNNRYDAQQIIERRREALSKIDNAEFGWFHIRACLVAGVGFFTDAYDIFAIGLVTPMIGTVYYPGGVLPSDLDLGIKVSASVGTFLGQVGFGYLADRLGRKRMYGVELMIIIVATLGQALSGNGETLSISAALIIWRVIVGVGIGGDYPLSAVITSEFATTNRRGAMMAAVFAMQGFGYVTTGLVAIILLAGFKDMIIANPKNLDYVWRCLIGFGCLPALVAVYFRLTIPETPRYVLDIENNLNKAERDVATVFRENRNHLQSDDDNEVIENPVTNKGSLSDFCSYFSKRENFEVLFGTSMAWFALDVAFYGIGLNNSFILSQLNLGGVKDNVYGNNWNAAVGQIVVVLLGTVPGYWATVFTIERIGRIKIQLLGFAMSCILFAALGFAYDGIKNTSVALFVFLFALTQFFQNFGPNATTFIIPGEVFPTRYRSTGHGIAAGSGKLGAIIAQVGFAQLKDRGGSNKGIPDLLKIFALFMLIGLFVTFLIPETKGKTLEELSNEDEYSVSSREEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N349</accession>
    <name>A0A9P6N349_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">DNA topoisomerase</fullName>
            <ecNumber evidence="3 11">5.6.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">TOP3</name>
        <name evidence="17" type="ORF">BGZ80_001233</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.</text>
            <dbReference type="EC" id="5.6.2.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the type IA topoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.1" evidence="3 11"/>
    <dbReference type="EMBL" id="JAAAID010000128">
        <property type="protein sequence ID" value="KAG0022004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N349"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031422">
        <property type="term" value="C:RecQ family helicase-topoisomerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003917">
        <property type="term" value="F:DNA topoisomerase type I (single strand cut, ATP-independent) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00186">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03362">
        <property type="entry name" value="TOPRIM_TopoIA_TopoIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.290.10:FF:000001">
        <property type="entry name" value="DNA topoisomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.140:FF:000005">
        <property type="entry name" value="DNA topoisomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.460.10">
        <property type="entry name" value="Topoisomerase I, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.20.10">
        <property type="entry name" value="Topoisomerase I, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.290.10">
        <property type="entry name" value="Topoisomerase I, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000380">
        <property type="entry name" value="Topo_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003601">
        <property type="entry name" value="Topo_IA_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013497">
        <property type="entry name" value="Topo_IA_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013824">
        <property type="entry name" value="Topo_IA_cen_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013825">
        <property type="entry name" value="Topo_IA_cen_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013826">
        <property type="entry name" value="Topo_IA_cen_sub3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023405">
        <property type="entry name" value="Topo_IA_core_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003602">
        <property type="entry name" value="Topo_IA_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034144">
        <property type="entry name" value="TOPRIM_TopoIII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010666">
        <property type="entry name" value="Znf_GRF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11390:SF21">
        <property type="entry name" value="DNA TOPOISOMERASE 3-ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11390">
        <property type="entry name" value="PROKARYOTIC DNA TOPOISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01131">
        <property type="entry name" value="Topoisom_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06839">
        <property type="entry name" value="Zn_ribbon_GRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00417">
        <property type="entry name" value="PRTPISMRASEI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00437">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00436">
        <property type="entry name" value="TOP1Bc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56712">
        <property type="entry name" value="Prokaryotic type I DNA topoisomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52039">
        <property type="entry name" value="TOPO_IA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51999">
        <property type="entry name" value="ZF_GRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0799">Topoisomerase</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Toprim" evidence="14">
        <location>
            <begin position="2"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="Topo IA-type catalytic" evidence="16">
        <location>
            <begin position="165"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="domain" description="GRF-type" evidence="15">
        <location>
            <begin position="670"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="13">
        <location>
            <begin position="826"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="369"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="589"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="850"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="595"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="856"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="867"/>
            <end position="877"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS52039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0022004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="894" mass="100704" checksum="A26B5AF3C92C3B75" modified="2023-09-13" version="1">MRILCVAEKPAMSKSLAQILSNGQYSTRPTNDQYTRNFEFSYRLLNGTMAHVVMTAVRGHLQSSDFPQQYRKWSSCAPVELFEIEIEKSTSKDLISVENNLVQESRIADQVMIWTDCDREGENIGAEIANVCQRQNRRILVYRARFSSVTPAEVHRAMQNPVQLDMRQADAVDARIELDLRVGASFTRFQTLSFKSRFPELLDGVISYGPCQFPTLGFVVDQYRRVENFIPENFWKLEMKHNKDGLDATFVWQRGHLFDQLACLVIYESCLEAGGPNVVVTKVKSNPTAKYRPLPLTTVELQKNGSKFLSIPSDEIMTAAESLYVKGWISYPRTETDQFDLKYDLAGLVEKQTQNSQWGRFAQRLTEGGYRNPRKGKNNDQAHPPIHPVMHTDNLDGNEKKVYEFITRRFLACCAEDAKGDQTDVEVKVNTETFKATGLIIKERNYLDVYPYDKWTGAVLPNFIEGEEFIPTEFSMKSGATSPPTLLTESQLISLMDKNGIGTDATIAEHIKTITKREYVVRSKHDKEYVFTPSTLGISLLESNLKLICSGIKTKNEVVEEAINMYRSVFETVNRDKRVLQESLERYLGRGADFPPHPPPPPPPPRPQQPDNSGSRNPGSGDGQMQRENHRFISNTTFESASRSSGEFRPQHTMTVTSSVASSNTIVCLCDGGPTAVERRVTKEGENQGRLFFTCAKPRDKQCGFFVFSEDTGLSTTRQLSNYQHGVEESHPQRANGAIMEAFLQNLQNGNMVDSKPRCLCGLVAMELKSSNQNGRVFWRCSKQNKQIACKFFKWDDELDPNQPSTPWSGGQQLQQGSSYQADLECYRCHEKGHFANACTNGTNSKYGDGSSGFHSSESTRTTSTKSKSKVTTKRSSSKSGIMAVRVSKKARPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3G1</accession>
    <name>A0A9P6N3G1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CoA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_000350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000107">
        <property type="protein sequence ID" value="KAG0022392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3G1"/>
    <dbReference type="OrthoDB" id="5138418at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003781">
        <property type="entry name" value="CoA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33303:SF2">
        <property type="entry name" value="COA-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33303">
        <property type="entry name" value="CYTOPLASMIC PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13380">
        <property type="entry name" value="CoA_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00881">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CoA-binding" evidence="1">
        <location>
            <begin position="14"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0022392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="143" mass="15366" checksum="11581C83907651AF" modified="2023-09-13" version="1">MATPAVATLVREFFSSAEQKFAVVGASTNRSKFGNRVLRWYNDNGYTVVPVNPKEKTIESLGCVPNLSSLPGKPSDYHVSIITPPTVTKSILEEAHTNGIQHVWLQPGAESSEALAFANDVGMRILASGPCVIENGIPKADIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3X2</accession>
    <name>A0A9P6N3X2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cyclin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_011342</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the cyclin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000090">
        <property type="protein sequence ID" value="KAG0022736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3X2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20524">
        <property type="entry name" value="CYCLIN_CCNH_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20525">
        <property type="entry name" value="CYCLIN_CCNH_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043198">
        <property type="entry name" value="Cyclin/Ssn8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031658">
        <property type="entry name" value="Cyclin_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10026">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16899">
        <property type="entry name" value="Cyclin_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0195">Cyclin</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-like" evidence="4">
        <location>
            <begin position="119"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin-like" evidence="4">
        <location>
            <begin position="223"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="343"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="25"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="354"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="366"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0022736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="382" mass="44469" checksum="ACE0A6F6EF636967" modified="2023-09-13" version="1">MSTATEAINGNGPDNTPTLTAASTDLEKAVEDSNDSKKEVPLKQLYEQSTQYNHWRYTQSALNEMRSKVNQEVITTIKQNIEEEREQRTAQGLSVDDLPVDLKFLNVEEEQALLGFYERRIVQIFRYWKLPSHVTATAIMYMKRFFLENTVMDFHPKDVMLTCMFLARKTENFLMTIDEFSTALKSPPESILNLEFLVCKNLRFHFTVHHPYRPCLGFFYDMQALTENIERLQTVYESAIKLIDTSLYTDLCFLYQPSQIALAAMRIACKKESYDYERYANYKFRSNESSAQKYDEILLPILLNIEKILNEDPRCIEVEKSVATEIDRRLKMCKDPAKNSESLIYGKRKRMEANGDDDDDDDDKDDDRPDKRAKMGDDSSPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N428</accession>
    <name>A0A9P6N428_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BGZ80_006664</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000033">
        <property type="protein sequence ID" value="KAG0024013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N428"/>
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        <property type="component" value="Unassembled WGS sequence"/>
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        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
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        <property type="project" value="InterPro"/>
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    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
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    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
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    <dbReference type="GO" id="GO:0005319">
        <property type="term" value="F:lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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    <dbReference type="CDD" id="cd03263">
        <property type="entry name" value="ABC_subfamily_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000665">
        <property type="entry name" value="ABC transporter A family member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
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    <dbReference type="InterPro" id="IPR026082">
        <property type="entry name" value="ABCA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229:SF36">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12698">
        <property type="entry name" value="ABC2_membrane_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="72"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="458"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="497"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="535"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="564"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="593"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="633"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="740"/>
            <end position="971"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0024013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1054" mass="116550" checksum="616967614E666E11" modified="2023-09-13" version="1">MSDATDGNKTLSGGHDEALATIDSISNEHASNQGVVFNAPNQALEHSPKTGRKSFQFRALGRKTLSYQRRQVFVNVCCIGLCPILMVVIAGAMGIVITSLINNLGNPLDYLLCSDVDAMTSRGFPMVPSTSDEKVNFPTSPGYTIPNAKPDASINHVNWFIIPGNLGFGSSPTITADSCVWWFENDYPYSSPYAKDPNITTPGANLDTTYKPQPQGGWLGPSELMVPVELTTQQTYPWLLVADETGGLAGTRPQQPLVDATTGNLTGQSFGTGLLGNMDTRYYANITTDPDTLIPSITGFQAVPFYQQVSGSGSGSSSDVDDALTREIRVLVEGLALVNKSAIRAKDPTSQELIEYYSQIGSLVQNMPIGALIFNAIDAVARKYDYTLQIGTDIRLMSAANYPDRGLRLMQQHTALIGAIFNTSSVANATKITHGFRGMPQLYSTKADLPIASLVGRILYPFGVSFLLPIFVITIVKEKEDRILVMMKMSGLKSVTYYVAHYIHFYILHIIASLMFIIAGVAFRMPFFTKVAPGVFLILFFCWGHAQIALAFFLSCFFSKSRTALVIVFLLVLCGVIVSLATETIFDTDPAPIGYFVWPAFAFYRALSVINRSSYDSSYQPYKVSDLKGSDEVFEVIIALIIETFVFLGLAFYLTEVLPTEFGVRQPWHFVFSTPYKRIFGKKNKGDIEGQVRQDHTGSWREKIQGEIPLDPEEVQFEDADVKQERARVLHDEFSQDSPLVMKNMRKIYPSNNKLAVKNVTFAVDKDTIFGLLGPNGAGKTSLIHILTGLYEPTQGWARLAGYELDTEIKDVYRNIGVCPQHDILWDDLTVGEHLYFYARLKGIEAADERAAVLASLEAVSLIPFENRLTKGLSGGEKRRLSIAIALVGNPGIVFLDEPTTGLDISVRRLIWDIVFNAKQGRTIVLTTHSMEEAEVLCSKIGIMAKGTLRCIGNQIRLKELYGRGFKISFASKPENTERASNYIASLLPENAKRLDSFVTSESWEFETSPGLIQRLFDEIEAHKQEHGIDDWGLSQTTLEEVFLRIIQDADADA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4E5</accession>
    <name>A0A9P6N4E5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Membrane bound c2 domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_010285</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000007">
        <property type="protein sequence ID" value="KAG0024706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061817">
        <property type="term" value="P:endoplasmic reticulum-plasma membrane tethering"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006869">
        <property type="term" value="P:lipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00030">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04044">
        <property type="entry name" value="C2A_Tricalbin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21678">
        <property type="entry name" value="SMP_TCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037761">
        <property type="entry name" value="C2A_Tricalbin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031468">
        <property type="entry name" value="SMP_LBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056910">
        <property type="entry name" value="TCB1-3_C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017147">
        <property type="entry name" value="Tricalbin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052455">
        <property type="entry name" value="Tricalbin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46980">
        <property type="entry name" value="TRICALBIN-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46980:SF2">
        <property type="entry name" value="TRICALBIN-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24920">
        <property type="entry name" value="C2_TCB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25669">
        <property type="entry name" value="SMP_MUG190-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037232">
        <property type="entry name" value="Tricalbin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51847">
        <property type="entry name" value="SMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="4" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="183"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="SMP-LTD" evidence="9">
        <location>
            <begin position="232"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="8">
        <location>
            <begin position="430"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="8">
        <location>
            <begin position="706"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="8">
        <location>
            <begin position="904"/>
            <end position="1017"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="8">
        <location>
            <begin position="1026"/>
            <end position="1154"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="8">
        <location>
            <begin position="1360"/>
            <end position="1480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="53"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1252"/>
            <end position="1356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1476"/>
            <end position="1496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="63"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="83"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1258"/>
            <end position="1268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1281"/>
            <end position="1295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="1296"/>
            <end position="1321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1330"/>
            <end position="1339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1478"/>
            <end position="1487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0024706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1496" mass="163896" checksum="734CACD8FBBD5736" modified="2023-09-13" version="1">MDPTQQPTEQNGSVPLPAVVPDHVKDDFTPPEIPGKAILNETLGKAIGGTVIASDILPADMPTTEKLDAKKEQEPAKLPAQQPSPKSTPSSPEVSKAIENGSLEKDAIAKKSNIIQDIKKRVPGAFPTMPRISWLDAYKRVDSPTNEFRDKSIWMEEFASSALFGSFWHNAAALFVIPVVCYLVFKLGGGIVSLILIIAFGATYYKNSIRRFRRNARDDITRELIRNALEDDAETTEWINNFLAKFWLIYEPVLCTSIVQTVDGILVDSTPSFLESIRLTTFTLGTKSPRVENIKSFPKTDPDVVLMDWRLSFTPTDIEDMTPRQLRTQINPKICLTIRAGKGLVGAGIPILVEDISFRGHVRLKLKLMSNFPHIKTLDFCFLDPPEIDYVLKPVGGNTFGFDIAHIPGLHAFIRDQIHTILRPMMYAPNVYTLDLEQMMTGGASLTAAAGVVQFTIYNAKDLKNTELVGNSDPYCKIRLGNRPKLGTTAVKEDTLNPVWNETYFILVNNLNEVVSMELFDKDNVRKDRPLGQANFDLKSLEEEPIQDDVWCNVLRNGKERGAVRIRAAYFPIQAPQPSADGQTMVPVESNTGILALNLAQAKDIARSGKAKSHCVVYLNGKEIHSTKSMKGANPAWGADVDAFVTDLSAAQIAIEVVADDRVVGSFAAPATKVIKDTTDKIDWVTLSGGDGVGKLKLNGVWKPILMGEDMSPTVYKPPIGIIRVQMFAGRNLRNVEIGSESDPYILITGDKGVSRGRTKTIEDNLNPVWNEIFYLTVNSVKQVFEFECFDYQKMTKDRTLGLTSFTVSELVEELPDKGGYTARPKVDRWAPLKQKDGSNKGEIHYELSFYPSLKLAEEATEAEKTDGATPVDKDAAATPANNVTLAETVKTTDPSPQAVVETAATTLPPGTIYKSEALDHDSGILVTHLISAELDRSNTYCEFFIDSDNSQFRSQNQKSRNPKWNEVADIFVKELEYAKLVIVVKEKSSMEKDNVIGTFTELVRTLLESTPADGGKFPIVDKHDTRGSLRLKFEYLPVPIELLPREKLDNMGNMNVTLVRAKDLIAADRGGVSDPYFVFKLNGKEIYKSDVIKKTLNPEYNESFDVPVGSRADDHFTFEVFDWNQVQAAKSLGTGSVDLRNLQLVLPNQFLIPLTNKQNQGEVQLRVKFMPEFLSSSKKSGFASTFIGGGINAGVGAVSTVGHGAIDVTGNVGKGAIKGVTTIGKGVGAVGKGVGKGVFGGLSAGASALGLHHKDKSSKSDKSDRASIDTPVMEPPPTTLPTSSQPQLQSQPEPQTQPQPQSQPQPQSQPQPQQPQPQPQPQFQSPEPSVEKTEKTENNIRTSNSEATLHVPRDSVGSIRSRTSVIFEHGEVVGEPGNLTVHLIEADGLMGVDKSGTSDPYVRVSIGGKNIYKTKVKKENLSPNWGESVVISGVTGQPVTINFLPSTEAHPGEYKADFWAPLSGSGGRLHLALQFEPSREGGDSGKQKRGLFGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4H3</accession>
    <name>A0A9P6N4H3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006069</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000003">
        <property type="protein sequence ID" value="KAG0024796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N4H3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0024796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="168" mass="18778" checksum="ABBA99E670B22BC6" modified="2023-09-13" version="1">MAFGFDRTLLGSSKLLSRFISSHIPSVNSALVLLQWKSVVYDLTSGSVLDVDDEDIDGSCTGDILDDAEDDDESCVRYILDDDEDEVDSEVGEEKASDDGNVDDDGFWSSEYLREMKLQVENQQVENEDFSETDFPSSTPPREEKELGEYAFSSPTRPRTPIGSRQDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4L1</accession>
    <name>A0A9P6N4L1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">2-nitropropane dioxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_000023</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000001">
        <property type="protein sequence ID" value="KAG0024895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N4L1"/>
    <dbReference type="OrthoDB" id="2349068at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018580">
        <property type="term" value="F:nitronate monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04730">
        <property type="entry name" value="NPD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004136">
        <property type="entry name" value="NMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32332">
        <property type="entry name" value="2-NITROPROPANE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32332:SF31">
        <property type="entry name" value="2-NITROPROPANE DIOXYGENASE FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G09850)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03060">
        <property type="entry name" value="NMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51412">
        <property type="entry name" value="Inosine monophosphate dehydrogenase (IMPDH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0288">FMN</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0024895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="391" mass="42726" checksum="79AA4E70A2B96D8A" modified="2023-09-13" version="1">MSASKNAFLATFKHLTRAGASNSASARVPRITKPIVAAPMNGWTGPNLVAAVANHGGFPVFPIGYFTDRNAIIKEVRSVLPLLKDPELHKDDDEVEFLPYGVGFITFWLDQQGPELLINLLEGKGDDPNRQSRPRPPAAVWFSFGDYKPYLKLIRERRPGTKVLVQVQTVQEALEAQRENVDVIVLQGTESGGHGIQKVSPLMTLIPTAVQALKDEIALEAARGSKLNMPAILAAGGISVASQFAAVQAMGASGAVIGTGFMPTYESSGPQHAKERLLQTGDGGINTVRTRIFDELRGIDWPQPYDGRVVRNLLTNREEEDLRERGLYQQKGLAAFRLIKEDRTGTKEDWVRAAKEQDLDIVPLWAGTGVGMLTKQASAAEFIDQLIGEQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N5J7</accession>
    <name>A0A9P6N5J7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 12">tRNA (uracil-O(2)-)-methyltransferase</fullName>
            <ecNumber evidence="4 12">2.1.1.211</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">TRMT44</name>
        <name evidence="14" type="ORF">BGZ80_006975</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Adenosyl-L-methionine (AdoMet)-dependent tRNA (uracil-O(2)-)-methyltransferase.</text>
    </comment>
    <comment type="function">
        <text evidence="1">Probable adenosyl-L-methionine (AdoMet)-dependent tRNA (uracil-O(2)-)-methyltransferase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 12">
            <text>uridine(44) in tRNA(Ser) + S-adenosyl-L-methionine = 2'-O-methyluridine(44) in tRNA(Ser) + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:43100"/>
            <dbReference type="Rhea" id="RHEA-COMP:10339"/>
            <dbReference type="Rhea" id="RHEA-COMP:10340"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74478"/>
            <dbReference type="EC" id="2.1.1.211"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the TRM44 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.211" evidence="4 12"/>
    <dbReference type="EMBL" id="JAAAID010000035">
        <property type="protein sequence ID" value="KAG0023961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N5J7"/>
    <dbReference type="OrthoDB" id="10047021at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141101">
        <property type="term" value="F:tRNA(Ser) (uridine(44)-2'-O-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011671">
        <property type="entry name" value="tRNA_uracil_MeTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21210">
        <property type="entry name" value="TRNA (URACIL-O(2)-)-METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21210:SF0">
        <property type="entry name" value="TRNA (URACIL-O(2)-)-METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07757">
        <property type="entry name" value="AdoMet_MTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 12 14" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 12" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="8 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="10 12" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="560"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="565"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="575"/>
            <end position="589"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU368004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0023961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="595" mass="68451" checksum="E9896D01E9A4433F" modified="2023-09-13" version="1">MSGEESSNLEFTFDPIFYFENLPNNQGQTRKDGGVAEVTQPKWYQAAKAPVPFNEDVFWKVMERWVLEAPSIIPPISKVDIIHDHELEQTQKNGEMSNLPVSAFTTEREQLLLESKPPFRSIRRRLLPKRANKDPIMEEQLYYVRSQYSKTEATEQPEDEAMIVGTKSHAIFSPVIDLQSAKEQVQSEIEAMTTKLPFYYPKVRGFRYGFVPDQEDDEDIFHHHGEEEESQFEKGRNYEYIKDENYQEQPNIDRGSGTGGKTKSTTLSKRAGWITLDLFLVGDEGEFTDKMQYAFKELFRKLYKWGVNTTKGFTKSRVQHDVMVPKELYLETYARLKDKHAQKWVQSWPEKTDPRKFVFEDIAIASWLVALWELERKRNHDSSGGQQTKKQTFVDLGCGNGLLTHILNQEGHEGKGIDIASRKVWEVYGSTTRVEARTIIPNETTFDNVDWIIGNHADELAPWIPIIAMRSKPLTSRYQFPKGAPEGKYKAYQDYICSIINTCGYSLETEILRIPSTKNVALVGMALIKENGQEQKQHKCEEVDDLVRRSGVFVARVSDKEKQALQKSKQAAKQQTREHEEGQLTHKENGSSNVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N647</accession>
    <name>A0A9P6N647_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Nucleolar GTP-binding protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">NOG2</name>
        <name evidence="10" type="ORF">BGZ80_005242</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 7">GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 7">Nucleus</location>
            <location evidence="2 7">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000026">
        <property type="protein sequence ID" value="KAG0024204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N647"/>
    <dbReference type="OrthoDB" id="444945at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01858">
        <property type="entry name" value="NGP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000559">
        <property type="entry name" value="Nuclear/nucleolar GTPase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1580.10:FF:000001">
        <property type="entry name" value="Nucleolar GTP-binding protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030378">
        <property type="entry name" value="G_CP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024929">
        <property type="entry name" value="GNL2_CP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023179">
        <property type="entry name" value="GTP-bd_ortho_bundle_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012971">
        <property type="entry name" value="NOG2_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050755">
        <property type="entry name" value="TRAFAC_YlqF/YawG_RiboMat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11089">
        <property type="entry name" value="GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11089:SF9">
        <property type="entry name" value="NUCLEOLAR GTP-BINDING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08153">
        <property type="entry name" value="NGP1NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51721">
        <property type="entry name" value="G_CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CP-type G" evidence="9">
        <location>
            <begin position="204"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="457"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="513"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="593"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="648"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="462"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="552"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="569"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="603"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="661"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="705"/>
            <end position="720"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0024204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="726" mass="81701" checksum="AB3414298B3F8830" modified="2023-09-13" version="1">MGQLKKEHNRVKASGGSNGLGNVKVKGENFYRDAKAAKQVQLLKGGRAIRNAQGKIIKAAAFQSKVVEPGRVAPNRKWFGNTRVIGQKALESFRENLATKVNDPFQVLLKQHKLPMSLLQDPVHVGKMHVLETEPFGDTFGNKAQRKRPKLAMSTLEDLAAKVESTLENYDEKADKNLQSNIITDWIEEARDSVFQKGQSKRIWGELYKVIDSSDVVIHVLDARDPMGTRCSNVEHHIKKEARHKQLIFVLNKCDLVPTWVTAKWVKTLSKEYPTLAFHASINNSFGKGSLIQLLRQFSTLHSDKKQISVGFIGYPNTGKSSIINTLRGKKVCNVAPIPGETKVWQYITLMKRIYLIDCPGVVHPSTTDTETDIVLKGVVRVENIKQPDDYIPELLSRVRPEYIQRTYELDHWEDSVDFLTQLAKRTGKLIKGGEADLGSVAKMVLNDWLRGKIPYYTPPPEGDKPGGESVEEESHSTVDHSLPQVEQIFSKIPVMQKFMADDLAKNASLLEEEKNKQESSAPEGVLPNEVDEDDINKTDDEGEDKSNAGVKARKSKAQLRQEKKAKKEAKSKTVSGEKLDWDDVFANVVGETVDSIPGQEDKDVEEDVDSELELSDEGAERKQRIKKRAALKRAGAVAAGFEVKDAKKTQKNVKRKHVEEEAEEEEEEEEAKPVKEARMTTNKGKIGTHYYETANVKNKNRNKVKPEDPHKLATKLRDQGKRRRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SRL8</accession>
    <name>A0A9P6SRL8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_008072</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004274">
        <property type="protein sequence ID" value="KAF9993636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SRL8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00821">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="183"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="128"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9993636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="283" mass="31805" checksum="2D2D3BBC37183475" modified="2023-09-13" version="1" fragment="single">FNDSSSLQKTLQSSVFDKHHKTLPEPPTPINQTNSISIDEFYYNASKNSSTNYNKNNNNNNNNNNNNNNSLYQQQLRRHPHNKSTSDTNGSIKELYLQTSDLASMTTDDEVSSTASFRQRSRKLSKAGSIPSPLSGSSSFSTVKNGSSNALSFLSTADRANTANSTVDTKTVSQLRVRHLEQHSSYAGYLTKFSSRTFFSRKQWKRRYFILSETTLYCFKSSDPQHPLLESIVLSPEAIVCVTDIFSGKRFCIEVSCPGEKSWYILADTAPEMSGWLKELKNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SRX5</accession>
    <name>A0A9P6SRX5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_007736</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004003">
        <property type="protein sequence ID" value="KAF9994729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SRX5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000072">
        <property type="entry name" value="Unconventional Myosin IB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050384">
        <property type="entry name" value="Endophilin_SH3RF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14167:SF81">
        <property type="entry name" value="ENDOPHILIN-A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14167">
        <property type="entry name" value="SH3 DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01887">
        <property type="entry name" value="SPECTRNALPHA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="7">
        <location>
            <begin position="7"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9994729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="86" mass="9918" checksum="2FD73C117AB6FC87" modified="2023-09-13" version="1" fragment="single">MVSETLDVQVLVRALYDYDSEDATNLTFKKDEVIQVLAQLESGWWAGYCQGRQGWFPSNYVQVLEEGDLDSQDEDDEEYQEGDDLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SSI9</accession>
    <name>A0A9P6SSI9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007146</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003601">
        <property type="protein sequence ID" value="KAF9996898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SSI9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004379">
        <property type="term" value="F:glycylpeptide N-tetradecanoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022678">
        <property type="entry name" value="NMT_CS"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00976">
        <property type="entry name" value="NMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040397188" evidence="1">
        <location>
            <begin position="20"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9996898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="101" mass="11143" checksum="7EB9168048B11355" modified="2023-09-13" version="1" fragment="single">MHVLACLTILSLIVKTAYASFGFCIALNNPGARQIAGFKLWNDQGEQAQEYRTLILARKTTLENSGWTLNLKFGGGDGFILDQVDIRNDKYGDIGEAAFEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6STE8</accession>
    <name>A0A9P6STE8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Extracellular membrane protein CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006395</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003158">
        <property type="protein sequence ID" value="KAG0000246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6STE8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040213254" description="Extracellular membrane protein CFEM domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0000246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="99" mass="10281" checksum="045CBFAA0CB612DD" modified="2023-09-13" version="1" fragment="single">MKSFATIASTLAVIATVSAIGPVDPNKLPTGWCMMYTDGCSEDVAPVICGANSTITSTCNSTFSNDLVCTSFKVSCLCTPATGGEQKDLSLEALNNTFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SUV2</accession>
    <name>A0A9P6SUV2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_005598</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NRDE2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002756">
        <property type="protein sequence ID" value="KAG0004564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SUV2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902369">
        <property type="term" value="P:negative regulation of RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031048">
        <property type="term" value="P:regulatory ncRNA-mediated heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013633">
        <property type="entry name" value="NRDE-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13471:SF0">
        <property type="entry name" value="NUCLEAR EXOSOME REGULATOR NRDE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13471">
        <property type="entry name" value="TETRATRICOPEPTIDE-LIKE HELICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08424">
        <property type="entry name" value="NRDE-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="554"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="775"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="775"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="792"/>
            <end position="807"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0004564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="807" mass="92415" checksum="1C6A06E44E02C8FE" modified="2023-09-13" version="1">MPPSLATEPWEIQIGSLEEYWDSELPRFGEKDAKGWTHYVTEEDEVAVDNLLDITKLPSMEAPTEELIKAFADNDVERYRYSRWAKLEKTLNTLCWFPIRTTDDMPDQLDDDPYGIIIFDDIRPFIVPLYTSEARQQYVDCMFNFLGVPMNSFAGSSGPRSLASPKLAKSGDIYNPYFHDSLLMNASIEVQSTLDASSGLRRFFPEFESKENLVERMMKEIEREQEFLEPEERDWSCVWNIPVRSFPQCTDVIFGKVKRDSKSYPWAIVSSHDEVQISNKVFIRNILQQLNEVVPLAKAHRRSLSLYHLMYEAFDTLSASKGQKLAKKYLKVDKMDLEMWNGYAQAEVALGRISEARKVYSTTLSMYQSFPKENQTRVPLIHRYFAELEWSQGRPGVALAILVAFAEANQVNITDDANDLPIPTPTRLIKARQFYSQKVAQLNLIRPSRNAADSDSIGAKWFEPALDLIVCFAWFEYLSSSAGTDAAHRETRRQHQPLLFSSLSVSSDVLLAETTTTKKKICTSVEAELVWIQLAKLVYFHSLKAMSSLRRSPATKTVSGDHDTSKSEGNGFQPRDLRRVVQAGLERFPNCAILQSLFFWTEAKQRLHGRVRTWANEQIMRSQGARRGGSSGFSGGPLASRASMWIFGLFYELWNQEPYNPHMVRSILESALETSKSSSFSSSPVLWFIYIELELRESARERGSILSNTKDKGSKPSDVESSTRVKQLLLRALNDCPWCKDLYLIAFEPRMRGLFSLDELDQLYQTMLEKEIRVRHEIPEREPPRIAQNQEGNDEDDDVTMDEEDAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SVP7</accession>
    <name>A0A9P6SVP7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">3',5'-cyclic-nucleotide phosphodiesterase (PDEase) (3':5'-CNP)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">CNA1_2</name>
        <name evidence="2" type="ORF">BGZ80_005139</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002550">
        <property type="protein sequence ID" value="KAG0006793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SVP7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033192">
        <property type="term" value="F:calmodulin-dependent protein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097720">
        <property type="term" value="P:calcineurin-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043360">
        <property type="entry name" value="PP2B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45673">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE 2B CATALYTIC SUBUNIT 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="1">
        <location>
            <begin position="120"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0006793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="173" mass="19627" checksum="26A2AF755F107D07" modified="2023-09-13" version="1">MSSSQAATATAKEAQAQAALRNLQYKKPVPEIDFTIHIMDDGTTASTLERYSKDVQAPAVNIPTDDVFYSKEFPDRPDIAFLKNHFYREGRITEDQAIYILQKGTELLKKEPNLLEVDAPITVCGDIHGQYYDLMKLFEVGGNPADTRYLFLGDYVDRGYFSIEVRPVSFYQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWZ2</accession>
    <name>A0A9P6SWZ2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_002661</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001665">
        <property type="protein sequence ID" value="KAG0009179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWZ2"/>
    <dbReference type="OrthoDB" id="2422218at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040417861" evidence="2">
        <location>
            <begin position="26"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0009179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="220" mass="24208" checksum="498E0F3B35EB8DEB" modified="2023-09-13" version="1">MRFSVASAVVAVSSLALLSSSRVSAALTAKERAAYELTAGPEPNFCDPCLSKAMHNHFPHACEPGLDSKTANKRPSGPTDAETRCVCVAFQDLSWMKADCSAECPYVFNKKTMSFFMPSSKIKGCDKWIDFATGKEKLVEGFAPKDDNHTPEVFEIAPAPPQEVSHPDDALDEEGHFKVSVHVTHDEKKKAELEAKEVEEKQEEAKSENESKTESKKDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SX78</accession>
    <name>A0A9P6SX78_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_003014</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001775">
        <property type="protein sequence ID" value="KAG0008822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SX78"/>
    <dbReference type="OrthoDB" id="3269380at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051580">
        <property type="entry name" value="ZnF-Chromatin_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23057">
        <property type="entry name" value="JUXTAPOSED WITH ANOTHER ZINC FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23057:SF0">
        <property type="entry name" value="JUXTAPOSED WITH ANOTHER ZINC FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="392"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="70"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="125"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="70"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0008822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="589" mass="63047" checksum="A0B1E06E312A7C5E" modified="2023-09-13" version="1">MDLSSTSFRFDGDFERQQSPSLADNLHAREFETAFCRDFHCCGLRLLDLHDLLQHYEECHVRFGEDDLAQTENESDSFDEDGWSDSDSPPSSPISASPSDSAFDVLDGSPASDLSAAAAHLYPTLQPHYPQPLDPRTNHSLPQHPIIHSTHPLYRRPSNDSSLTNVKCNSDAQALEAFAASLNGPTKRKAAVSLTDIYTEDDGHASGDNSAFPDAIVRAKVSESHSGLDFLSPLAKRLAMESDQRSIATSIYSEAHAPRPIESNGSGVWPSPFSNGQNSGPQGIHQEDLQLPTIYPTLAGRHGPIGPLSKLSTPSFVQSAADILRQRDEVYSLMEDLTRSGNTNAGDKPYRCTVLGCDKAYKNPNGLKYHNLHGHCSTGGMCVADSPESKPYVCTFLECGKRYKNLNGLKYHIEHSHPNLTAALRAHHSGLINPGIFGLYPSEAAMTIAAALQAVSSSPMMMAAASAILTAQAIISANTNLNSGLIPESGIGTGLMLGPQTDPLSCPWSNPNTKTLCEPEWVQRTGSISPPKLGPGLVSAAGLGETPSPTPFFDESVKENISIGSIHSAFQSGLPNFTAVSTTGTAVAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXI9</accession>
    <name>A0A9P6SXI9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_002091</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001505">
        <property type="protein sequence ID" value="KAG0009761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXI9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0009761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="97" mass="11167" checksum="BB81A1C6B18EE6E9" modified="2023-09-13" version="1" fragment="single">WLTKSKSRNPGPSSATKRVTRSMSQKHPTVPEQSQEDDQYDDQDIGQYDDQDIGQYDDQGDDQYDDQGDDQYDGQDQDDNQDDNQDEGNDNSVKWES</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYM1</accession>
    <name>A0A9P6SYM1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 14">Uroporphyrinogen decarboxylase</fullName>
            <ecNumber evidence="4 14">4.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">HEM12</name>
        <name evidence="18" type="ORF">BGZ80_000190</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Catalyzes the sequential decarboxylation of four acetate groups of uroporphyrinogen-III (octacarboxyporphyrin) to yield coproporphyrinogen-III (tetracarboxyporphyrin) with the formation of intermediate hepta-, hexa- and penta-carboxylate porphyrinogens in the heme biosynthesis pathway. Acts on a number of porphyrinogens, but only coproporphyrinogen III can ultimately be converted to heme.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>uroporphyrinogen I + 4 H(+) = coproporphyrinogen I + 4 CO2</text>
            <dbReference type="Rhea" id="RHEA:31239"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:62626"/>
            <dbReference type="ChEBI" id="CHEBI:62631"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 14">
            <text>uroporphyrinogen III + 4 H(+) = coproporphyrinogen III + 4 CO2</text>
            <dbReference type="Rhea" id="RHEA:19865"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57308"/>
            <dbReference type="ChEBI" id="CHEBI:57309"/>
            <dbReference type="EC" id="4.1.1.37"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 14">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 4/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the uroporphyrinogen decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.37" evidence="4 14"/>
    <dbReference type="EMBL" id="JAAAID010001032">
        <property type="protein sequence ID" value="KAG0012125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYM1"/>
    <dbReference type="OrthoDB" id="339900at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004853">
        <property type="term" value="F:uroporphyrinogen decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006783">
        <property type="term" value="P:heme biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00717">
        <property type="entry name" value="URO-D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.210:FF:000004">
        <property type="entry name" value="Uroporphyrinogen decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00218">
        <property type="entry name" value="URO_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038071">
        <property type="entry name" value="UROD/MetE-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006361">
        <property type="entry name" value="Uroporphyrinogen_deCO2ase_HemE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000257">
        <property type="entry name" value="Uroporphyrinogen_deCOase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01464">
        <property type="entry name" value="hemE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21091">
        <property type="entry name" value="METHYLTETRAHYDROFOLATE:HOMOCYSTEINE METHYLTRANSFERASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21091:SF169">
        <property type="entry name" value="UROPORPHYRINOGEN DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01208">
        <property type="entry name" value="URO-D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51726">
        <property type="entry name" value="UROD/MetE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00906">
        <property type="entry name" value="UROD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00907">
        <property type="entry name" value="UROD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 14" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="8" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="9 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="10 14" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uroporphyrinogen decarboxylase (URO-D)" evidence="16">
        <location>
            <begin position="28"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="domain" description="Uroporphyrinogen decarboxylase (URO-D)" evidence="17">
        <location>
            <begin position="151"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00052550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00058098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU004169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS00907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAG0012125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="369" mass="40865" checksum="AACB737AFE5310CA" modified="2023-09-13" version="1">MSASKPFPPLKNDLILRAARGEKTERAPVWVMRQAGRYLPEFRAERVENDFFKICRTPELATKVTLQPIDRYAGLLDASIIFSDILVVPQAMGMTVEMIPGKGPHFPDPLVLPQDMTTKLKEKVDVQKELQYVFDAITMTRHELDGRVPLIGFVGAPWTLMAYMIEGGGSKTLSKAKEWLFKYPKASQELLGRITDVCIDFLVGQVRAGAQMLQVFDSWGGELSPQDFDLFSLPYLTQIAKRVKAELGSEAVPMTVFAKGSWYALDQLSDIGYDAVSLDWTHTPESAKAITKGRVTLQGNMDPNVLFGGDEAIIAAVEKMVRGFGSTERYIANLGHGILPTVPVEAMELFLKTVHRVGLEVAAESADKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYS7</accession>
    <name>A0A9P6SYS7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Multidrug resistance-associated protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ABCC1_5</name>
        <name evidence="12" type="ORF">BGZ80_011737</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000981">
        <property type="protein sequence ID" value="KAG0012452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18579">
        <property type="entry name" value="ABC_6TM_ABCC_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18580">
        <property type="entry name" value="ABC_6TM_ABCC_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000006">
        <property type="entry name" value="ATP-binding cassette, sub-family C (CFTR/MRP), member 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000010">
        <property type="entry name" value="Multidrug resistance-associated ABC transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000997">
        <property type="entry name" value="Multidrug resistance-associated protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000163">
        <property type="entry name" value="Multidrug resistance-associated protein member 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044746">
        <property type="entry name" value="ABCC_6TM_D1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044726">
        <property type="entry name" value="ABCC_6TM_D2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF415">
        <property type="entry name" value="FI20190P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="98"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="240"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="280"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="357"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="381"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="467"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="924"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="966"/>
            <end position="988"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1042"/>
            <end position="1060"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1066"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1151"/>
            <end position="1169"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="247"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="596"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="926"/>
            <end position="1204"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="1240"/>
            <end position="1512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="842"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0012452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1517" mass="169389" checksum="EBBD0B97353364C4" modified="2023-09-13" version="1" fragment="single">VLFGALSLLAIGGFVSRVHYLIRHGVAHNLGRTAWIYWPTQICMTLAAVIAWSLSLRFFLRGADFPIAAWSCLGMGIAWTLAVISNRYEHECEIRSSSGIYTFYVLSIASALVIIKTALDFESPGDLTVVLLIALTSVLTIGFVVEAWPRGSTRVQQLSGVGLYGKANLGSRLLFTFFMPFIRIGFHRTLTQEDILGQLPKDMEIEVVHEKLSRTWNEQLRKRKSSEDTPSLLMTIMTSSWPVLVPVLLSRVAIVFFSYTLPVFLKELLNYLENYESKPVSYGVTLAIGMFISSLFASLLNTYNRYQMLLIGVKTRAALIAMIYRKALRLSVRSRNETTSGEITNHMSVDADQWWDMIVYLSMWISIPIEVGIAMKLLYDLLGWTMLAGVLVMVAMLPVQTWQARVIKEMQREKLKAMDQRVNMTTDVLASMKIIKLYGWSAAFMARILAVRQNELEALRKMGVIQAFMSIIFISSSLIISLVTFSVYALWGGPNFTPGQLTPQTVFVSMTLFAMLKGPIASLSDATTSTIGVLVATKRIQNFLLKEEVNDKDILRFDSLSRDPLEPVISIKDATFSWTGPIEEKPRIVDERSTLLSEQDNSSQLTIPPTLQFINLAVGRGSLTAVVGRVGQGKSSLLSAMISDMYKIQGKVQISGTVAYVPQQAWIINKTLRDNIVFGKEYDEARYKRVVFACGLEPDLAMLPAGDMTEIGERGINLSGGQKQRVSLARAAYSDADIYLLDDPLSAVDAHVDRHLWNNLLGPSGLLREKTRVLVTHGIHHLREVDQIVLLNNGVIEENGHYSDLMVSKKAFYRLIKEYSILERRKSQSTIAGVKNRRKSTDVVESAATAETETPGDVSESSLDDGISEASTSDPHTEEAVVPQEIKHEKRDTKAELITAELMKEGDVGYGIAIDYAKAVSYRLSVIIVVLFLLAQGCLLLSSLWLKHWIKKNDETTDVVLFLGVYSLLTLVYVLLYVVVTWLLFAVARIRAAERIHFNLLDKILHLPIAFFDTTPLGRIINRFSSDIAAVDTRIPNKLSDVLLFGISVSSTLLLIVFTIPSFIFVIPFLIGGYWLVLVCFLGASRSLTRIYSISKSPVYQHFNESLGGVSTMRAMRIHDQFIAANSSLSNRMSNNFLCNMSSRRWMDVQLRLLSTGVLLCTALLAVLGRKHMDPALVGLTLSFALSITEEVTTLVRNVCDLQNQLIAMERVLEYTNLKTEAPDTTNVLIPPNWPSRGRISFQNYSTRYREGLDLVIKNVNLEVAPAERVGIVGRTGAGKSSLTLALFRIVEAANSYWAKESDNSVTLDPTAFAERAKYLEDNCDSDEEDEDGGKIEIDGIDISTIGLRDLRQHLAIIPQDPTLFAGSVRENLDPFHELQDADLWEALDRSHLKDFISTLPGGLSFEVSQNGENFSVGQRSLICLARALLRKTKILVMDEATAAVDVETDELIQKTIRKEFKDRTILTIAHRIKTVMDSDKILVLEKGRVLEFDAPSRLLKNNESLFYKLAEQAGEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYZ4</accession>
    <name>A0A9P6SYZ4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_011482</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000929">
        <property type="protein sequence ID" value="KAG0012821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYZ4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0012821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="64" mass="7446" checksum="F8DEBDB129E93689" modified="2023-09-13" version="1" fragment="single">SPIETRLLEVVSGNTTKFIHSIELSTFNVLETVDIWFWNLAYDTVWKGRGKVQKEVLSHLQNQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZA2</accession>
    <name>A0A9P6SZA2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_011080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000847">
        <property type="protein sequence ID" value="KAG0013430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZA2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="15"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0013430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="180" mass="20576" checksum="39C8D4051AC08F85" modified="2023-09-13" version="1">MTRYDKSSLGMTNRTLVPSSLPTNPSPLSVLGLDENGEQKERPRGQEEERRDTAKPIPWHKLYISTTMPSGAQSSLSLPVDAQSQSHSTKMNKQRAKAAIQFKHIITSFWGRSNLFQERVQVLDIFQDTAELERGERVRTLRSRHLINLLSNPCSPTEGYRLEQEFKADQERLVLITEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-02-05" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZC5</accession>
    <name>A0A9P6SZC5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_011364</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000903">
        <property type="protein sequence ID" value="KAG0013015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1273"/>
            <end position="1296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1458"/>
            <end position="1481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1458"/>
            <end position="1472"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0013015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1610" mass="180135" checksum="AD8345F4C645DD82" modified="2023-09-13" version="1" fragment="single">MSSLTYTATEFRDLENYALNPELRDDLVKACTPNSKEWYLSQLRFLSQELQEVSANPSKDAKSSAIAGKFEKALKLLREYEPFALNGDRTELERLKAQFAILGYSVNPDMLLKELDFNPDTIAQLSNSIVFVQTDTDNEQSDICDSLPTTLDESLFDIESLSQQLMDKLISDYNTSVPNSAWPHLLAQPQMRDILLKTMSPTELLTQLERMSLEWSSKSLEMLKGSSTSDTSDWVALDQSQMQSPVEALIVDVILRLYQEKKLDFAGYKIQYSSLTNAQMEWIKEKEPGMMNNERFVGMLEHRIVPRVFDSSPTETGKVTDPKTTVRGEWLARMMAFVDSLPPKYNRHRLAVFLMSLEYDLANGVYDKDKFMKFIEIPRNHDYYNPSTLKKVFEPSFIVDTNNTQALQYWSDRVKPATKARDEHIIQEFLYYFLQKEKSGVDYEYYFDVKSFLNPILARSMLFSGDQDILKWSSMLAPSDGGIAKLTEKTIIRFANGNPKSFLPSDPVVFKLKVKNTKRILVRVFEIKTLEYLQQYGDSSAFGQVLNLDGLTPNWEKHLILDYPPLEMHDLQIDLPELADRRGAFVMDVISNGENSSAYFTKGYLDFVEKQSVAGHILTIIDEDKRKIDQDVGIWFNGFYYKTNKYGDIVIPYRNPKVAIDKNIYITHNDFTSRRPFTHHPETYSMSLCCYIDHESLVAGSVAKILIKAVVQIDSVNVTCPVKLLDQVVLEVVSHDTSGIEGTVTIPDFKLHDNDWTEYSFQVPENLSSVEFSLSAKIKVISTGRFDDLSDRKNFTIERSSCDDVVVVHVQHRKQDVLLQGEILTVLRASTTNGTDTVYEIHVMGKNGEKRPNIPLEVSLVHPLWYTSLDVFLRSDSEGIVHLGKLQDISEIRCNRLTWDLLPKRKHSYPNTIHGIAGEPVILPFSRRDVLFIRSISLYRRSSATFTASRCLFEDLTGNIKLGDGILTIKDLHEGYYKLNLGEEAIGIIISNAKIVSHPAIKGLEEFNIESDPMMRIPYSIKHPLYLSSVVDKPSEEKIQIQIRNWTPATRVCVVATKFLPYKPIFESLGELDSRPIWLKPQAERIPTVYRTGRVLGEEYQYILNRKAQSKHWVGNFLTKPSVLLTPLSIGATTMSQEVMANQNFNNGPCAANGFGGAPNRAGGQGLGRGGAMRHRRILLPGAHPLLTFFSNPSVLLANLIPNQRTGIVELPYSKSSETNFLQILVTDGTQAIQHSCALPSLAKKNLQKRDLRFKSSQDYTKHYISERIGVGLDPKPSSLSPDDGAESSHSITLSANGSSSSAVRVINSVSQVYDLMITLLESEAHKQTLRRFGFIVEWHKLSDPQKNEKFSKWNCHELNLFLYNKDRPFFDLVVAPFIKNKLIKSFVDDYLIGASLEKYTSLSEFSLLTCMEKCLLAHRIPRLRSSVAKWIRSRVHNTKVTSDVKLFRTVMKFGATEDEEAEGGEGGEGGEGDNAYGVVPNTSVEAGVSSEGFELVERPGFGSTFGASSTSAFGQPSTSTSGLFGLSAAPSGFGSSASQSGASLFGSSAAPSGTFSFGSSAAPPPSGLFGFGSTTNSGGFGGFGGLGAAAQSGSQLQAQTQQQQQQQNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZL3</accession>
    <name>A0A9P6SZL3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">tRNA (guanine(10)-N(2))-methyltransferase</fullName>
            <ecNumber evidence="9">2.1.1.214</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BGZ80_010787</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM11 methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.214" evidence="9"/>
    <dbReference type="EMBL" id="JAAAID010000791">
        <property type="protein sequence ID" value="KAG0013877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZL3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043527">
        <property type="term" value="C:tRNA methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160102">
        <property type="term" value="F:tRNA (guanine(10)-N2)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000241">
        <property type="entry name" value="RlmKL-like_Mtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016691">
        <property type="entry name" value="TRMT11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059073">
        <property type="entry name" value="TRMT11_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13370">
        <property type="entry name" value="RNA METHYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13370:SF3">
        <property type="entry name" value="TRNA (GUANINE(10)-N2)-METHYLTRANSFERASE HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25904">
        <property type="entry name" value="Tmrp11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01170">
        <property type="entry name" value="UPF0020"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017259">
        <property type="entry name" value="tRNA_mtfrase_TRM11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00507">
        <property type="entry name" value="N12N6MTFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51627">
        <property type="entry name" value="SAM_MT_TRM11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 10" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="3 10" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="tRNA (guanine(10)-N(2))-methyltransferase TRMT11 N-terminal" evidence="13">
        <location>
            <begin position="6"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal RNA large subunit methyltransferase K/L-like methyltransferase" evidence="12">
        <location>
            <begin position="150"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="434"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="441"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00066937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF25904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0013877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="460" mass="51763" checksum="6641DF59DFBDDEF8" modified="2023-09-13" version="1">MTYNPSDYSLESPFLIVEIDSAEKAASLLKRAILIKTIVELWGTGSSWDELIEKVKEHPERWPQYLYTTFKFSVVTFGGTIEMKDKPEIINRFSFTGFLGKIDLKNPEEEFLLIADYGIDPNVKVAHTFYMGRLIGHGRRDLIDKFNVKKRKYIGNTTMDAELSLIMANQALCGPGKLVYDPFVGTGSFLMTCAHFGAMTVGSDIDGRQIRGKGKASIQSNCEQYNLKGRVLDALVFDVCHAPWRKINGGLFDAIVTDPPYGVRAGAKTLGRKDPTKQATEPRMAVEEGVLAHLLPDYIPPTKPYEMSEVVADLLMFAVKNLVRGGRLVYWLPTVTEDYAIDDLPTHPCMELVSNCEQAFGQWSRRLITMEKVSDWDGEAALGPPTGDMNKSTTVPKRQGHFGFRNRYFAFNIVENAKRKKELKEAYQKGGPEAVAAYMRQSEEKKKQGQQEADSRQQQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZQ5</accession>
    <name>A0A9P6SZQ5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_010640</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000761">
        <property type="protein sequence ID" value="KAG0014125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZQ5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0014125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="257" mass="26548" checksum="2939752BC7326FB1" modified="2023-09-13" version="1">MVEDAEVEVRVEMGGFDGSAVGSIYCVDEDDLFQRSEALNILSLGAVDIAEDIPGVDDAKTLSRLLDEEEEEEEEERIPSRIHLCCRAAYAFVVAAADVGGGDGWVIVGAPATTRLMMLESWHLTDSNHKCGIVVVKILVGAMLYLADMLMREELDLALMMKETAVVSSNSAVVVDGDVRHATAVGDAGDDVAAAAAAVAVVGVSAEIGVHGTVVGSGRPGVSTVCPHDGIARSDVVAVADGCDDAVVAAAGHLMGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T005</accession>
    <name>A0A9P6T005_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Nuclear condensin complex subunit 3 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_010262</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CND3 (condensin subunit 3) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000698">
        <property type="protein sequence ID" value="KAG0014714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T005"/>
    <dbReference type="OrthoDB" id="27187at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000793">
        <property type="term" value="C:condensed chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000796">
        <property type="term" value="C:condensin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007076">
        <property type="term" value="P:mitotic chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027165">
        <property type="entry name" value="CND3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025977">
        <property type="entry name" value="Cnd3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14418:SF5">
        <property type="entry name" value="CONDENSIN COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14418">
        <property type="entry name" value="CONDENSIN COMPLEX SUBUNIT 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12719">
        <property type="entry name" value="Cnd3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6" id="KW-0226">DNA condensation</keyword>
    <keyword evidence="5" id="KW-0498">Mitosis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nuclear condensin complex subunit 3 C-terminal" evidence="9">
        <location>
            <begin position="571"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="507"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="925"/>
            <end position="996"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="14"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="515"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="932"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="952"/>
            <end position="966"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="972"/>
            <end position="996"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0014714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="996" mass="113145" checksum="752E80C1CB8F76F3" modified="2023-09-13" version="1">MARPKKQAGDAVATGSSKNGASSTRPRKQNAIDTLRTVVPSIFQESQKTSANHRKNAIMLRKIQEQCAEIAGEKGEEAFNKEFIRNLNVVLAIKKKEPTADRVIQFASSFILCTREKDMAAEAANEDEEGEEGISSRFVEYLMRHLLKGVRVKEKQVRLRSCQLIALSTNSLGAIDDDLYTQLKESLMERVRDKEAAVRVQAVFALTKLQGGDDEGEDGNNDDDSVVQKLLDLMQHDPSADVRRSAFFNIEQTKTTLPYILQRARDTDAYNRRGVFTKPMEELSDFRVLSIGDRERLLRYGLSDRDENVKKACTKMLATKWIQQADDNLLEFLERLDVMSSNVADDVLKAFFDYRVDILGNFAFNDVFWANLTVESAFLVRAYAEFCRGKDDDIQFEKAVPEVTRHAFYIQKYSNIMQEADEDSRPEAEFIVTQLLMIARLLDYADENGRRKMFNLLREMLMLDDIPDKHLDCIVETMGKISLNEKDFTRIVIEIISDIRAGIDEQEFLRNPERSDDEDDSPDDQTMDLADTPRKRKRSIVDKSPRRRSSVAVEEVGQSANDLDAMLIRVRCLNITKFMLERSAEPLKENSYMYGLLNELVIPALGRQEDLMQELGLHCLGLICMLDQNLARNNMELFLTCIFAENASNQVKLLSLKIVFDLILTFGMTAMSSLITEEKIVQDLANSLESPIDQIQAVAAEGIAKLMLTRLLKDPQILRKLIILYFDPETVNKYHLRQCLSYFLQVYFHSSHENQVTLSEIFIPIIIQLIHMQQDAKGEMPTPSNMAQQLLEWCEPRRVLGADLENEGAVASGNIDFGLQANIAIELVKAMFTETSAVRKHLPLVLYKIRLDGDAGEIRLKKLTLLIGNLKARRPLTELLSKKYLLSVEKNILKMFEDAPEALDDAELNKLTELTEEISFLDKYEPPEEPAETVAAAPPSARARRGAASKKQTPDERLAKIMKEVDAILESSESEQEAQDSESEEEAQDDDEDYDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1E1</accession>
    <name>A0A9P6T1E1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NADH:flavin oxidoreductase/NADH oxidase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_007951</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000418">
        <property type="protein sequence ID" value="KAG0017755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1E1"/>
    <dbReference type="OrthoDB" id="72788at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003959">
        <property type="term" value="F:NADPH dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02932">
        <property type="entry name" value="OYE_YqiM_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044152">
        <property type="entry name" value="YqjM-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43303">
        <property type="entry name" value="NADPH DEHYDROGENASE C23G7.10C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43303:SF4">
        <property type="entry name" value="NADPH DEHYDROGENASE C23G7.10C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0288">FMN</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:flavin oxidoreductase/NADH oxidase N-terminal" evidence="6">
        <location>
            <begin position="68"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0017755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="427" mass="46272" checksum="B6B01DF163D1C2AC" modified="2023-09-13" version="1">MLPIHRILTSTARPAVSRAMRTSRLPISSLNTTFAKAFTTSQISRQEAFRIKPSVAPGTSTGKDTPLLFQPFNVKDLTIANRLVVAPMCMYSSKDGYMTDFHLVHLGSFAINGAGLVLAEATAVDPRGRISPADTGIWSDNHIPAIKRVADFVHSQGSKFGIQLAHAGRKASVNAPYNSEAFSETEYWRDDVVGPSGGPESRWDEKHAVPRALTVSEIQDVVKAFGAAAARAAKAGADTVEIQSVHGYLIHQFLSPVSNQRTDQYGGSLENRARLMLEVIKEVRANFPAEKPIFMRISGSDCVEHLDIPSWDIEQTVQVSKWAKEAGVDVLHLSSAGNTPLQKVAYAPGYQVHYAERVRKEVPGLPVIAVGSITGGKQAQEILESGKADLIAGARTFLKQPSFVLEAARELGVEVAYAPQYSLAKTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1I0</accession>
    <name>A0A9P6T1I0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Molybdopterin synthase sulfur carrier subunit</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Molybdenum cofactor synthesis protein 2 small subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Molybdenum cofactor synthesis protein 2A</fullName>
            <shortName evidence="5">MOCS2A</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Sulfur carrier protein MOCS2A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_007950</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Acts as a sulfur carrier required for molybdopterin biosynthesis. Component of the molybdopterin synthase complex that catalyzes the conversion of precursor Z into molybdopterin by mediating the incorporation of 2 sulfur atoms into precursor Z to generate a dithiolene group. In the complex, serves as sulfur donor by being thiocarboxylated (-COSH) at its C-terminus by UBA4. After interaction with MOCS2B, the sulfur is then transferred to precursor Z to form molybdopterin.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Heterotetramer; composed of 2 small (MOCS2A) and 2 large (MOCS2B) subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="5">C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of UBA4, then thiocarboxylated (-COSH) via the rhodanese domain of UBA4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the MoaD family. MOCS2A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000418">
        <property type="protein sequence ID" value="KAG0017754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1I0"/>
    <dbReference type="OrthoDB" id="5595860at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990133">
        <property type="term" value="C:molybdopterin adenylyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990140">
        <property type="term" value="C:molybdopterin synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030366">
        <property type="term" value="F:molybdopterin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00754">
        <property type="entry name" value="Ubl_MoaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03051">
        <property type="entry name" value="MOCS2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044672">
        <property type="entry name" value="MOCS2A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028887">
        <property type="entry name" value="MOCS2A_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016155">
        <property type="entry name" value="Mopterin_synth/thiamin_S_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003749">
        <property type="entry name" value="ThiS/MoaD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33359">
        <property type="entry name" value="MOLYBDOPTERIN SYNTHASE SULFUR CARRIER SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33359:SF1">
        <property type="entry name" value="MOLYBDOPTERIN SYNTHASE SULFUR CARRIER SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02597">
        <property type="entry name" value="ThiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54285">
        <property type="entry name" value="MoaD/ThiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040295918" description="Molybdopterin synthase sulfur carrier subunit" evidence="6">
        <location>
            <begin position="24"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="modified residue" description="1-thioglycine; alternate" evidence="5">
        <location>
            <position position="110"/>
        </location>
    </feature>
    <feature type="modified residue" description="Glycyl adenylate; alternate" evidence="5">
        <location>
            <position position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0017754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="110" mass="12161" checksum="8E4C81346B1DFBBD" modified="2023-09-13" version="1">MSHVSAALVILLIYFSVHRFVLTQGNFAQFTVLYFASAKDASKVDTDKFEWSAGINAQTLTNLLVERHPDLGYVLKTSMFAVNMEYMENDSSWTVQPGDEVAIIPPVSGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1K8</accession>
    <name>A0A9P6T1K8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Chitin synthase activator</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007099</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000358">
        <property type="protein sequence ID" value="KAG0018488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1K8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051726">
        <property type="entry name" value="Chitin_Synth_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46430:SF1">
        <property type="entry name" value="CHITIN SYNTHASE REGULATOR SKT5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46430">
        <property type="entry name" value="PROTEIN SKT5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0018488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="417" mass="47281" checksum="A5A42F92BBFD448B" modified="2023-09-13" version="1">MNMDDQQQQQYEYDQQLYQQEQYEQAQLWQQQQALQQQLQQFPQEDMLGQDQSVLSHDHLKPGHKATLLSYTQTLELYRQNAKKTNDPELQFEFAAFMIDAGKQLEDPQTRAELFDEALKLLRKLATNGHAESQYYLAECFASGFAKGKPDFDKAFPLWVQASKHGHPDAAYRTGRCYDEGLGTRKDNARAVQFYRKAASANHPGAMWRLGVVTLYGELGLSASPRDGVKWLKRAAQAATPEFPFALYELAQLHERGIENIVFVDPEYSVSLYSQAAELGHAASAFRLGECWEYGKLGCKQDPRLSIHYYTLAAQQEHPEACFALAAWYLVGAVGILPQSDDEAYIWARRAADKDLAKALYAMGYFTEVGIGPRKDMEEAIEWYKKASAAGDTRATQRLKGVPVDAKDKRDEKCTIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1S4</accession>
    <name>A0A9P6T1S4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Ras- protein Rab-6A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">RAB6A</name>
        <name evidence="8" type="ORF">BGZ80_007030</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000353">
        <property type="protein sequence ID" value="KAG0018556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1S4"/>
    <dbReference type="OrthoDB" id="9989112at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01861">
        <property type="entry name" value="Rab6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000229">
        <property type="entry name" value="Probable Ras-related protein Rab-6A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050227">
        <property type="entry name" value="Rab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47977">
        <property type="entry name" value="RAS-RELATED PROTEIN RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0636">Prenylation</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0018556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="209" mass="23521" checksum="E91ADAEC596F7181" modified="2023-09-13" version="1">MATNPEFSNPLRKFKLVFLGEQSVGKTSLITRFMYDTFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQERFRSLIPSYIRDSSVAVVVYDITNRNSFMNTAKWIDDVRAERGTDVIIVLVGNKTDLNEKRQVTAEEGEKKAKEFNIMFIETSAKAGHNVKTLFRKIAQALPGMENTITDANQSQLIDVKIQDNPGATEGANGCAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T229</accession>
    <name>A0A9P6T229_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007399</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000378">
        <property type="protein sequence ID" value="KAG0018247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T229"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="497"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="539"/>
            <end position="565"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0018247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="565" mass="64078" checksum="4A5F1C3EB3F4960D" modified="2023-09-13" version="1">MASTKLTVTEKDIEWFNASDDHTPEAFFNHLKTINRNKAYLRYKRVLRDYNTGDAYRKRLVEDFDTWQSEEADAYWEERKAKKTAKSAQVRTAVTLARTSVPFAAQEIHATLSSAKSNQDAATQQSPGSKRTLACSATTAQGSPTKKTKKTKKSKQDLAVARRSERFHGQDKSRFWRLSSGKVVEETLYRASLESGASTSVRSYTIDASCPKTRALFTSQEWNEVVSSVSFQLPELHKKTLAFIEKLRPGLCENKHPYTVPLSNDPTMSDADLFDCNLAVKTAVEWHMLYTKKPSPFIVDDLSESWWARASWALLFNLLDDTPGIFTVDGEKRGLDSSKRRNMGRTYNPEESGHKKCGRKLDLICRDEVQKHDWLVFERMRGWDPRSTKFLRELSHDVVRETVTITHNRLVDVPTSFREKCVFVGGYSGSRGVDAFQIKPGPGRSYVLLMQHVGQYTLCPVNGELKEQFQGLVRLLQVRVSMKNTIELYKSLIGANPSDPFPTTESESDHGNLDWYYDDPEPRFDPNQVVSSSPIGPDDLCDLDDLDDLGELSSDPEDSCETETD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T288</accession>
    <name>A0A9P6T288_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Chitin synthase activator</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_005070</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000252">
        <property type="protein sequence ID" value="KAG0019919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T288"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="58"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="60"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="93"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0019919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="406" mass="44981" checksum="93C4799D067959FD" modified="2023-09-13" version="1">MKVHLFPFSRTKTLICNPFKLAIRLFYCSIQENWAYGSDLIRPSETNSVHPASTIIDNPAQRTSSAPQHQNSGVSATVAPIPDLHDLPPQYTRDGNATSSTPSGISHTTATNQTVDTNSNDSTPEVGILRNIGGEGSEDYEQGLEYYYGKGVPIDYNVAKEWFIEAADHGHVAARYYLAYMLENGQGFFEDSSGAVSRYIEAGSTGYDNDECNARYHRGKLAKALHWYREAADKGDARAQCVLGFMYHRGRGTLNDQRSAKEWYKKAADQGYDNAQYNLGLMWEECDGTADDYTEAAELYFRAVFQGHARAQCNLGDMHAFGRGVCENESKAAEWYAKSADQGYDRAQCRLAEACIDGIGIPVNFPKGVELLHKLAAQGYAQAQVMLGNLYFTGRGVRRNTNTAKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T329</accession>
    <name>A0A9P6T329_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">UDP-galactose transporter homolog 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">HUT1_2</name>
        <name evidence="11" type="ORF">BGZ80_002242</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000155">
        <property type="protein sequence ID" value="KAG0021503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T329"/>
    <dbReference type="OrthoDB" id="1601at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005459">
        <property type="term" value="F:UDP-galactose transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005460">
        <property type="term" value="F:UDP-glucose transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013657">
        <property type="entry name" value="SCL35B1-4/HUT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10778">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10778:SF10">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08449">
        <property type="entry name" value="UAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="39"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="104"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="160"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="199"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="237"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="262"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="288"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00041103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0021503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="323" mass="36447" checksum="E086D6BC5D2C137A" modified="2023-09-13" version="1">MLRLAGCVAGIYTCFLTWGYYQEKVSTTPYGQDARKFKYFIFLGLVQALFASTIAYLYLKIQGLNIQKPSKPLLIKYLQVALIAVTAPPFSYAALKHIDYPTMILTKSCKLVPVMLMNILLYRRKFPTYKYVCVALVTIGVSGFMLLGTADGHKKGAVNSSLYGLFLVTINLTLDGVINSTQDQIFHAYKVTGQQMMCIMNLFMSGYMILWLLNPWNPELTDALTFCQTHPAIIKDIIMFSICGALGQCFIFYTLEKYGSLSLVTVTVTRKLFTILLSVVAYDHKLNLHQWLMVVVVFMGIGLEAYVKRVEKLEKMASKGKQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3S8</accession>
    <name>A0A9P6T3S8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Calcium-binding protein NCS-1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">NCS1</name>
        <name evidence="9" type="ORF">BGZ80_011186</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the recoverin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000087">
        <property type="protein sequence ID" value="KAG0022776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3S8"/>
    <dbReference type="OrthoDB" id="191686at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000009">
        <property type="entry name" value="Visinin-like protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028846">
        <property type="entry name" value="Recoverin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23055">
        <property type="entry name" value="CALCIUM BINDING PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23055:SF178">
        <property type="entry name" value="NEUROCALCIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00036">
        <property type="entry name" value="EF-hand_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00450">
        <property type="entry name" value="RECOVERIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0519">Myristate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="8">
        <location>
            <begin position="60"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="8">
        <location>
            <begin position="96"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="8">
        <location>
            <begin position="144"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00071944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0022776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="190" mass="21943" checksum="0D6515AD30D75F60" modified="2023-09-13" version="1">MGKSQSKLTPEELKTLQHETKFDKKELQQWYKGFVKDCPSGELDKTEFQKIYKQFFPFGDPSTFADYVFNVFDANKNGKIEFKEFIVALSVTSRGDLEDKLKWAFQLYDIDNDNSITYDEMLSIVDAIYKMVGTMVKLPADEDTPDKRVTKIFSLMDKDKDGKLTFEEFKEGSMKDPTIVQALSLYDGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T483</accession>
    <name>A0A9P6T483_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_000084</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000101">
        <property type="protein sequence ID" value="KAG0022513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T483"/>
    <dbReference type="OrthoDB" id="2390483at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0022513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="104" mass="11161" checksum="15F54E945DFCDBFA" modified="2023-09-13" version="1">MGKKTATAAVNQKQNCACGRHSMGEKEACRFCPNVVCDSCREEYCCGPVCEKCNDDREHLMKCDTCDAPVCEKCIVITKGAREGNSCKSCKSGNAVAAEASIRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MCJ4</accession>
    <name>A0A9P6MCJ4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Reverse transcriptase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_008933</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010005013">
        <property type="protein sequence ID" value="KAF9991747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MCJ4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9991747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="156" mass="17219" checksum="F20DD9959A5CC6FD" modified="2023-09-13" version="1" fragment="single">MDAGLGYPVMRREALAEHHRIPFLVPETPDVELMISCLAFVDDSTWIGRNKQSTQGIVDIADSFYALNSIEINPKKSELLVINSTLAPDELTIQLGNDVLRALSPGTSARMLGVWFSADGKGVYTRQIVQQEVSSICKILARKAITDKQAIYIVNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MDH1</accession>
    <name>A0A9P6MDH1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_008127</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004310">
        <property type="protein sequence ID" value="KAF9993500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MDH1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9993500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="176" mass="19812" checksum="2B6DB4F585B2BF36" modified="2023-09-13" version="1" fragment="single">MTESGFQECGITYLKELATAIYEYQNGNPVVNYSAHLDRKTWKEAFFDEKDGSRLLREVIPLTRNGNQYRFIHKSLLEYGLSLAVFGSSELSEETGTIISVSRRGSTSPDLSFENSSSTERTATVNDAYLLGSPLGKRNLVGEVSVLQFLTERVQQEPVFKDQLLSVIERSKTDKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MDM3</accession>
    <name>A0A9P6MDM3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HAMP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_007909</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004149">
        <property type="protein sequence ID" value="KAF9994126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MDM3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004673">
        <property type="term" value="F:protein histidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071474">
        <property type="term" value="P:cellular hyperosmotic response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06225">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1530:FF:000002">
        <property type="entry name" value="Two-component osmosensing histidine kinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1530">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45339">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45339:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18947">
        <property type="entry name" value="HAMP_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58104">
        <property type="entry name" value="Methyl-accepting chemotaxis protein (MCP) signaling domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="domain" description="HAMP" evidence="3">
        <location>
            <begin position="62"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="3">
        <location>
            <begin position="154"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="3">
        <location>
            <begin position="246"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="3">
        <location>
            <begin position="338"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9994126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="413" mass="44427" checksum="7071A3601E4AAA71" modified="2023-09-13" version="1" fragment="single">GEMMDLKNTINTMVDQLQEFATEVSRVSLEVGTEGKLGGQAVVKDVSGTWKELTDNVNTMASNLTTQVRSIAEVTTAVACGDLSKKIDVEAQGEISELKLTVNSMVEQLRTFAAEVTRVAREVGTEGRLGGQAHVKDVDGTWKELTDNVNTMAENLTAQVRDIANVSKAVARGDLSKKISVEVKGEMLDLKHTINTMVDQLQQFATEVSRVSLEVGTEGKLGGQAVVKDVSGTWKELTDNVNTMASNLTTQVRSIAEVTTAVACGDLSKKIDVEAQGEISELKLTVNSMVEQLRTFAAEVTRVAREVGTEGRLGGQALVKGVDGTWKELTDNVNTMAENLTAQVRDIANVSKAVARGDLSKKISVEVKGEMMDLKHTINIMVDQLQEFATEVTRVSLEVGTEGKLGGQAVVKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ME73</accession>
    <name>A0A9P6ME73_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_007772</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004030">
        <property type="protein sequence ID" value="KAF9994599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ME73"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9994599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="233" mass="25133" checksum="151A31410CA3EEC1" modified="2023-09-13" version="1" fragment="single">MFRNRLSSSTSGFPLKDTFELANKHLEDASNASSPAMARHHCDSAKAMIKSTENIVNKRVGGQTLNDDIANAYHKHGKLLEGLNQHSKAQKSYSKAEKWGYLHVVSQHSGPSQSISFNGSTLRSLFPPVALSATPALTVAVTQGILDLKVTPSTLQVHAKDTNPIQNDGQILATSTGATTALRKVFVKDGAPPVAKFTLPEIGERLTSTPQLAYCLSLLYPSLVSNEELNQPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MFN6</accession>
    <name>A0A9P6MFN6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PB1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_007225</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003662">
        <property type="protein sequence ID" value="KAF9996522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MFN6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05992">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000270">
        <property type="entry name" value="PB1_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00564">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00666">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54277">
        <property type="entry name" value="CAD &amp; PB1 domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PB1" evidence="2">
        <location>
            <begin position="2"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9996522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="166" mass="19123" checksum="040DB7C411826630" modified="2023-09-13" version="1" fragment="single">MAATVKAWFRDDCRRLSIDIEQIQYQDLKKKLQNTFQLDNEFMVKYADTEGDLCTITGNEEFDDLVKSDLVKERKGTIKLQVVPKNGSRRPSILHRRESSDQSADEKISRPFFDNEYTDCDMLEILRDISNFICTRGMDRHGEHENAMAELPPGASSWVSTGKNLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MG34</accession>
    <name>A0A9P6MG34_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_006740</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003342">
        <property type="protein sequence ID" value="KAF9998637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MG34"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9998637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="223" mass="25245" checksum="3FBD55DAF98F0A57" modified="2023-09-13" version="1" fragment="single">MSNFVSHFGLNDRESATRSFQELLQSSQIPQKRREDLQAAFNYFQMHHEEKFWVKRALKHNTKVIATKAACAVQDAGLQEAEIAFDVVEDQNLRKDNLHHEMPAQKKPRICSSPSSLHGASSISLCHTPPYHQGSAESSPETFTNVPPSPLDLTFDDETEEHEAHSFFTSSGSSQDILFSNLQDGNSISPWAKNRPLYTFKLQLQEEWGPRVTDLYEAAKTKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MH70</accession>
    <name>A0A9P6MH70_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Copper radical oxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_006699</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003313">
        <property type="protein sequence ID" value="KAF9998884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MH70"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02851">
        <property type="entry name" value="E_set_GO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.80">
        <property type="entry name" value="Galactose oxidase/kelch, beta-propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037293">
        <property type="entry name" value="Gal_Oxidase_central_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009880">
        <property type="entry name" value="Glyoxal_oxidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015202">
        <property type="entry name" value="GO-like_E_set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32208:SF21">
        <property type="entry name" value="LOW QUALITY PROTEIN: ALDEHYDE OXIDASE GLOX-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32208">
        <property type="entry name" value="SECRETED PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07250">
        <property type="entry name" value="Glyoxal_oxid_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09118">
        <property type="entry name" value="GO-like_E_set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Glyoxal oxidase N-terminal" evidence="2">
        <location>
            <begin position="2"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="Galactose oxidase-like Early set" evidence="3">
        <location>
            <begin position="348"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9998884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="453" mass="49961" checksum="78F0A0ACCFD45C79" modified="2023-09-13" version="1" fragment="single">VLDVATNTFCSGGGFLPNGTLISGGGAEARLTHTFTATSGFQSLRMWEPCEDESCEWIENPADPAWQMTGNRWYVSITTLPSGELFVLGGSNESLAINRNATNNPTWEIYPKPLDYKPIFMQFMVDALPNNLYPNVYPLPDGSIYIFANQKSVIYNVTSQEEIKRLPDIPGGPRSYPLTGSNVLLPLDPAKNYAHEILVCGGSEAMSTRAKALQTCGRINIHADDPQWEMDMMPTPRLMSDAVILADGKIMLLNGAQIGYAGFLRASNPIYTPVVYDPDAPLGERFTEWVPSNIARMYHSVATLLPDGSVFVAGSNQNSEVRFENVPFPTEYRVESFTPPYLTTDLARPEIVTEIPATLTYDQKLDIVVDVKATDKYAPNVTFMLGHRGFVTHSTHMSQRMTKLVSTKVSEDGTKITYSVAMPPNANIMPPGPHYIHVLNNGVPSMALHFILN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MHK5</accession>
    <name>A0A9P6MHK5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_006203</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003052">
        <property type="protein sequence ID" value="KAG0001299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MHK5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0001299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="94" mass="10882" checksum="BCE196B672393CA6" modified="2023-09-13" version="1">MTVSLLPDRLCLLRFPREDLELCSHAILKHILFRDYSHSGHQQHEEPLFSYIDNSLEISIFGDAEALSKDFVKDICPRIEISTHIYRALQVDNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MHR4</accession>
    <name>A0A9P6MHR4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">1,3-beta-glucanosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">PGA5_3</name>
        <name evidence="4" type="ORF">BGZ80_006471</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003197">
        <property type="protein sequence ID" value="KAF9999886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MHR4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF51">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase A1" evidence="3">
        <location>
            <begin position="1"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="215"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9999886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="295" mass="31244" checksum="9F449CC5972D4F2B" modified="2023-09-13" version="1" fragment="single">GSAYIWFPSSTCTTSGCKAHNRFDAAKSSTYKKDGRTYDISYEDKSGASGILGSDIVNTIGLATAETAQFASDPNDGLFGLAFSGEESVRGVKTFMDYAIAAGVLAQPVLSVFLPSLRRNGDTGGEYLFGGIDSTKYSGNLAYIKVDQQDYWQIPVDDITYNSSSLGLSSDGIVDTSTILVMVGTKAAKAIHDNIQGAVFTAATSTDPAYWAVLCSLQSSTDSVGFSLGGKIFNVSVADIAYEDLDDGSGNCFSGIQGNPDEDNLWILGDVFIKNNYCVFDHGATPRVGIAPLNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MHS1</accession>
    <name>A0A9P6MHS1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_006243</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003076">
        <property type="protein sequence ID" value="KAG0001057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MHS1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0001057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="242" mass="27087" checksum="71EE85ABE6BCA0F3" modified="2023-09-13" version="1" fragment="single">IKKTQTPLVTMGQSYQLINISKRQISRTLGSAKMIEQLASKGNQPILALLLTEVGPTLSESSEPSKFMGTWSGDRIVLIGDYSYDTPSLLTEAEGQEIEATFDSYPSLYRFACDTYTLVSPAEPTNPFEDLDPAKVEELFLNSSEVHHLVLNLDKKEYLDPQKSKSPATSLKEFANLEFGVMQGLYSLIFYSNGSGGGDRKQFRDGRWAGDHLTIREKDKVDDLDSWTDISEMVVESLSEFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MI48</accession>
    <name>A0A9P6MI48_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003123">
        <property type="protein sequence ID" value="KAG0000579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MI48"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0000579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="132" mass="14893" checksum="35BF29D4D5E7C949" modified="2023-09-13" version="1" fragment="single">TWKVIGQYTKTCPDIYYEWPVLIPHNVPSCTNSDKCLFAMSWTAYNVDQYYHHCANVIIKGNKHGKLPTLDMTVVDVTQRHQKKDVHADGDHKDTKSSGPNPAEKKLNLKGAFAYGGSLKNKGVNLHLIKVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MIG5</accession>
    <name>A0A9P6MIG5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GTPase-activating protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">GYP5_1</name>
        <name evidence="3" type="ORF">BGZ80_005848</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002883">
        <property type="protein sequence ID" value="KAG0003118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MIG5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.80:FF:000027">
        <property type="entry name" value="GTPase activating protein (Evi5)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050302">
        <property type="entry name" value="Rab_GAP_TBC_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219:SF9">
        <property type="entry name" value="GTPASE ACTIVATING PROTEIN AND CENTROSOME-ASSOCIATED, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219">
        <property type="entry name" value="RAB GTPASE-ACTIVATING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23436">
        <property type="entry name" value="RabGap-TBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="2">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="172"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="250"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0003118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="309" mass="36214" checksum="E2B73BF25921A408" modified="2023-09-13" version="1">MPEEEAFCMLVRMMNSYAMRGNYTPDMSTLQLRLYQFEQLMEETVPLVYKHLRNQGIRSTMYASQWFMTLFAYKFPLDLVFRVFDIILVEGIESILRFAIALLKANHDKILGLDFDVLVEFLKDGLFEYYMNNASLFIQDAYNVKVTPRKLAQYAQKHQAMIQKQQADLAAEESLRETNKQLATQVQKLETSMSQLNKEHVDLAKELITRKVEMAELQDHNDVLTQKVSDLTKIVDSQAKEVEDRLRGEIEDVLRKNMEYLKKNEQLEDQLAYMESLLVETKMKYAESEIERDNLSRKLSDMRKALGMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MIY6</accession>
    <name>A0A9P6MIY6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">6-phosphogluconolactonase</fullName>
            <shortName evidence="6">6PGL</shortName>
            <ecNumber evidence="4 6">3.1.1.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">SOL1</name>
        <name evidence="8" type="ORF">BGZ80_005708</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12556"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57955"/>
            <dbReference type="ChEBI" id="CHEBI:58759"/>
            <dbReference type="EC" id="3.1.1.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 6">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.31" evidence="4 6"/>
    <dbReference type="EMBL" id="JAAAID010002804">
        <property type="protein sequence ID" value="KAG0003981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MIY6"/>
    <dbReference type="OrthoDB" id="432544at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017057">
        <property type="term" value="F:6-phosphogluconolactonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01400">
        <property type="entry name" value="6PGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1360:FF:000005">
        <property type="entry name" value="6-phosphogluconolactonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005900">
        <property type="entry name" value="6-phosphogluconolactonase_DevB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039104">
        <property type="entry name" value="6PGL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006148">
        <property type="entry name" value="Glc/Gal-6P_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01198">
        <property type="entry name" value="pgl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11054">
        <property type="entry name" value="6-PHOSPHOGLUCONOLACTONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11054:SF0">
        <property type="entry name" value="6-PHOSPHOGLUCONOLACTONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01182">
        <property type="entry name" value="Glucosamine_iso"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucosamine/galactosamine-6-phosphate isomerase" evidence="7">
        <location>
            <begin position="16"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0003981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="259" mass="28543" checksum="81ACE2D3D94A69E0" modified="2023-09-13" version="1">MPLHAAAATQIYTFSDVHALSQGLDKYVAKLSEEAIRRHGKFTVAISGGSLPKQLSAVLKHNQTVDFSKWIVYFADERCVPLDHEDSNYLLSKKELFDYVNIPAENIHTINPELVDDPEEAAEDYISQMTGTFATKDSVRFPVFDLILLGIGPDGHTCSLFPDHELLKENEAWCVSITDSPKPPPCRITLTFPVLNHAHNVAFVVAGEGKQDVLHHILDTAGHLPAQMVKPTTGSLSWFLDDAAAAKVTSTTQKGLERL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MJD2</accession>
    <name>A0A9P6MJD2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005655</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002785">
        <property type="protein sequence ID" value="KAG0004197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MJD2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="698"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="756"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="724"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="778"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="793"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="803"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="971"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0004197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="971" mass="106288" checksum="1E287B0E67962339" modified="2023-09-13" version="1" fragment="single">RICLNPDPRLAQQDLNGQREHLDIHNKDINSGDNLNVANGDSLGNFSTTENDASNGMEIDFGIDQDKRKPKEMTVPNPAAPLRNRMRSGLDTIQQQALHNQGSVLASDLSILGFIKLDAIQSPPVLSRHWITLDCSQEHDAITKTSIKDEQTSDGAEGPASTDLKMPKPDESLAALLFPSNQPLSQKHPNNQFTQRPPQHHQQPYTQSQTSFTGQSPGITHVSHIPKMPPTSSKPPLFYRDGSVANAPQDQQSYTSPTVPQHPAKPQSGKKNEKESESWSQEGVPQQHLYSTLHKALDQESMVAIVALQYPDKNCTRLRKWRRAQDEAPLRSTKQSSIPTAATLLSKRLSHSQGSSPNMQSTSASDLSMMAGNPSFGSMTGSGMMGSTLTTTLPIGSSAPKDDLSSALTMASLSTVVEADRSWCGLLMVASHFLGSPFYSTPVHLNDNLEHSKHPEQFVLLIMPKNAAVTNAPWIPDLNYDRPQLSARVPPLRTQFMSPHLSKISNRKSNEVSSKASHAVQETDLYLPRGMEQFGSVRAILMEIKADLAALCSIDDQAVKSKNRDRNLENKIHNNFLSLNSVEAVYGYKGGFNCAAKMLNKALDKLPDGDAKHRSLSKLIQTLLRADSSGIVIDFKMNNVDHDNQGGYEASESYDHQSISVVSPISSNARKSMEVEAKVEQPEIKRGEHRPMQDTVKNAGDRISSSQGDGIDGVAHGITHGREGEEEEEEEEQGADENLEVGNVRARIASGEIRDQLAVGKQQDTPESRPVKSATDIALTQTLPIQTQMDHDSEAEDIEQDTVMEQSSVPQSRWSSAHQKPESHIATATLEHQQLQRKEAVHGQSRLMSPGLAPQKRRRELRDDGSDDASSVEGVPTRPTAMSKTEENTDKPMPLLESSTSSQAAVEQIGQGVTQLGLKKGSKKSKRIKSELPDDNVLQNAQEEPAPVLADVGQDTQGYEMIGTTLQAKVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MLJ2</accession>
    <name>A0A9P6MLJ2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004920</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002460">
        <property type="protein sequence ID" value="KAG0007228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MLJ2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="224"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="608"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="99"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="257"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="608"/>
            <end position="617"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0007228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="633" mass="71747" checksum="F5EA98B6EE1959D5" modified="2023-09-13" version="1">MKTFKEFVATDSHKHPNYDKQYACYTAYIGRQRKAGDVAAQNYELSFELLKKEYDSLKMDGTISVSRDSAGKIIEASMHQYTSEAVQKIGGESLAPASYSSLVPTPASSSSDLATVQPFGSDEETLDDEDEGRGIMTSSMQHIPKHGTETKKPSVDDVVSDEEVVDFTIFNKTEQGKSELILCVTPPYRPPGPSDTESSEPELAINSKLGKHRLDQHDGLLWDSPNKHLGESEGEMDQTSRSQIGPTMGIPLPHQHTTSTSASASAPAPLSQCRKKSKIFSYSEIFAFLRQKTTWETTFDIGGYFSRIRGSLKSSFDISKDNIMDMTSASAFVMSLSDETYTEAMEDMPTLDFGLEEIKELKIIMEPECSFEELRDRIYGMPLDTPVRRYVYGVIESYAAFFDDNSVVPELEEKQGMFDVICPFVRGAFRVFRVPSNISEIAIMATGERRNFNQNYEDRLRNCKRADIVAADKDGIQIFLAECAMLHEKDVRKFTEDRWKVARCMKDIWDFGMRRTTQVQSPHENFSTFGLHSFGQELHFLQLDFRSSYRLWEIETCRVPLEIAGFWKKMITCCQTSLAFTKAVITEVERRKGQEMLSQKERLSLMRTANNIPRTTVSPPKPKIKKQQSSPIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MLJ7</accession>
    <name>A0A9P6MLJ7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_005122</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002543">
        <property type="protein sequence ID" value="KAG0006839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MLJ7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052671">
        <property type="entry name" value="Acrosomal_SP-10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17571:SF34">
        <property type="entry name" value="ACROSOMAL PROTEIN SP-10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17571">
        <property type="entry name" value="URINARY PROTEIN RUP /ACROSOMAL PROTEIN SP-10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="244"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="542"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="676"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="31"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="802"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0006839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="802" mass="89526" checksum="2A376EC1FFC27A2F" modified="2023-09-13" version="1" fragment="single">MSGGPAQAQAQNYEQNSPRAIALNEARVFSQQLQQQQQQQQQQQIQSHQQVDQSDVSRRTSWTGIGPRSVIGSMMNARVSTAASTIGGTSPVLGGGGGSVNGDEPTEQTLLLVRPVWVQDQDAAACRICSRTFSAVRRKIHGARGLYELIIANDEAIQSMIVAKRAMPKLFYIVWAYTNNTAPSVRPPSPPVVLARMASTTSLHTKNVRRTETIAAVLMNVTHIVFQMVPDKEAIKTMSMRQSGSEVGGLDSATVASQKSGDDLDYEDETTFSMNDELHSRLENMQSIAAKCISILASDVSNQAYIVDDPERISRLVQLLYSTNLDVVKYASKTMAYLSLRNDKYKPDIAKGSGAAALLAVIRAAGGDQMLSGNSVLAEAVSHACCALANLATNTESQEILMSHMDLLSATCSVVGLFPYQRDIERHVARLIANLALYDQNKLALLTAYNASPEGGIYDRSSSPYPSHYSYHSAAQNRYSSPPPQARRAKGNVIPTLLHIGSLTLEKVGFVGDQGTSETYPPLGQDVIDFMNDDGQATIHHNSGYLTPDNSVSGTDLSPRSSVEECTGLTHEDEVSEWATVPGMEDVQRHIIRAIDNLVTSVAEDPTSNQSFKVFSRIWPTLGLIKTIQMASHDEDTQRRATHVLSTLISQQEIHADAIAALRQREKALHPVQDPINQTKSEIDALTAMNNQAKEHEEREKLEKEKLEIERLEKERLEAEKLEKENEEKEKKRLEQERLEQERLKQERLEQERLKQERLEQERLKQELLEQERLEQERVEQERIEQERIEQERLEQERLEQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MLT7</accession>
    <name>A0A9P6MLT7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CRAL-TRIO domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_005010</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002499">
        <property type="protein sequence ID" value="KAG0007127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MLT7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011074">
        <property type="entry name" value="CRAL/TRIO_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052432">
        <property type="entry name" value="PITP/CRAL-TRIO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46590:SF1">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL TRANSFER PROTEIN CSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46590">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL TRANSFER PROTEIN CSR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03765">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01100">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="3">
        <location>
            <begin position="176"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="332"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="50"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0007127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="414" mass="46542" checksum="19798A24AF51196B" modified="2023-09-13" version="1">MGRTPSSPTGGPIHTRRASYGGPIFPTSKGDSPNRRSSSESRPISPTPASPTRLSQSFYQPSIASSPPHPTSPINSHLPGGAASAAAALRRSAAKLKPWLPAKKFTFKYSPAEYQTAFWSFVQCEHPDTVVLRFLRARKWNVEKAMEMLVLALEWRITMGVDEVLQESEDSIEAKCPGFLEQLKSGKVIFRGHDRQGRPLCLLDPSKHHQHAQSQQAVEKLSIYVIEAGRLMIIPPTETISVVFNMSNFSMSNMLLGVCLVHKAPWIFGALWKAISPMIDPIIRAKIKFTHNCHDLEEFIERDQLMRNEGYDGLDETPYEYVPPVPDENKLIQEDSEAKQRALAKRKELELTFERLTEIWQGQKQLSSNAAVMQERDEVGKRMAEVWWAAAPYTRAKSVYHRIDAIKPPAEVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MLV5</accession>
    <name>A0A9P6MLV5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004636</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002342">
        <property type="protein sequence ID" value="KAG0007462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MLV5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="345"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="345"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0007462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="396" mass="43214" checksum="128BBDA1D6224A09" modified="2023-09-13" version="1">MEGLHEKLPSTATDVEDAIKDILQSNPEFGVKSVLKEMHLKGLEIGTKEARSIVSRLKADIKDKEVHSTMSRSEADTQDKKFHSILFRSTADIQDKGIHNIVSNSKADIQEESPEQQICVANETSGAVSQYLDDVLCTMLKTPKEVVRNFQALTHVFNGFMGSYELNLACISRLIAQNPFYQRGDTTNTPLESCKLVTTLVMLLCSELSIKKIKTITSFLTRSSGGLDNLGSLPPNQGVLEAAVESAKKDMLRDRKCRALAASMTDLYVFRIPFQRESIAHSFVLVLSIDKDDRLKAGVGEASKKGVDVQKQKSDEQVAAEKIKKAEAAKAAIAQAKANVAARTAVPSSSASTPSSALQSSPAQPKVKKASRVVTLMKMRKSAQGEDKIPVSSRVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MM33</accession>
    <name>A0A9P6MM33_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Amino acid permease/ SLC12A domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_004444</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002268">
        <property type="protein sequence ID" value="KAG0007615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MM33"/>
    <dbReference type="OrthoDB" id="3900342at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015171">
        <property type="term" value="F:amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1740.10:FF:000001">
        <property type="entry name" value="Amino acid permease"/>
        <property type="match status" value="1"/>
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    </dbReference>
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        <property type="entry name" value="AMINO ACID PERMEASE"/>
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    </dbReference>
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        <property type="entry name" value="GENERAL AMINO-ACID PERMEASE GAP1"/>
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    </dbReference>
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        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
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    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="553" mass="60152" checksum="797F3F0555512005" modified="2023-09-13" version="1">MTHEHEGEKYDIDYMHDVSSSSTALAAEQQGLKRDLRLRHMIMIAISGTIGTGLFLTSGNTIADAGPAGAVLAYGIIGIWLVFVCQAIGEIATLLPLPGAFNAWGGRVFDEAFSFQMTWMYFINWALTIPAELSASAVAVSYWLPEGSSFPPWVVPLLIIIVMVAINVTGVKAYGEIEYWLSILKVCTIVVFIICGILVDAGAVGGTVYGFSNWSGEGAPFKGGFLTFVKVLVSVGFAYGGSEMTGVTAAESRNPHKHVPKAVNTVLVRIAFFYIVSVFLLASIINTNDPHLINTTKSAATAPFTLVFQKAGINVAANFMNAVVFTSIFSAINSDFYVATRMLLSLSRNGWAHKSIGYTNARGVPLVSLAIVTACSCLSLITVFVGSGVVFQWFVSIIGSIIFQSWILILFLHFRFRYCWKAQGRAVSDLPYVSWGYPYGNIIATFIGVLCIVANIYLSCIDPPVHPGDGASADAIRAYNSARDGYAQGLLSAFFPWVMSAILFFSYKFVRKTKMVKAEEADLDTGRFIPTDSDLKDMESHGPAWKKVVKFII</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMF3</accession>
    <name>A0A9P6MMF3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">BGZ80_004147</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
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            <taxon>Fungi incertae sedis</taxon>
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    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
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        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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        </source>
    </evidence>
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        <source>
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    </evidence>
    <sequence length="216" mass="23945" checksum="55A7671C8B5FFBE2" modified="2023-09-13" version="1">MVERVHVVTAIGVTRWNSRMFKFNIALVAPFSVIVVLAIKFRVAEIDDLGYCQIGLQTQASAPLIVYDTLINVWLTFLFMRSLISSTSKIQGSTGSKLRAVTQRTLIGAILSLILSSANIASFVVFNGHERDELCLALCTLDVTLNAVTIHWVTSPRRSLKASVKSTPNRDWPSKVDSATMEGQEVSPLRSHLSISIESYVEEYHPTHGPGREYSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
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    <name>A0A9P6MNJ5_9FUNG</name>
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        </submittedName>
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    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
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                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
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        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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    </feature>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="KAG0008244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="398" mass="44064" checksum="37018BAD8A4A20DE" modified="2023-09-13" version="1">MSNLKTILDRLVQESLHGPVDQGNQYSVKYQAIRQAAAARKMAEKSQNYNRAPYDDPDSDLIRSKEDDSFEDDGDLDSHDPRWRQLFHEFFLSENSDDRNDDLLFFVQKLPLEAENGGLGIDPVFVKRKVKNIAQRILTAEQESVVLWKDTFFLNVIVQLPCKLTVAVCSRVAETNPITGVTKTSMTCTQKHVSKRVYALPTKSRVDVKEATVECSWPLIYYVIDDYEDMFEQLLVRDNEYLCVELAVTLPSSTGSGPQNPSSPTSRQLHRGMSQETHWNHVSGNDGLQVGKPFPMISGRGGGSSGGSDKITLFQGAAGFSNLLGIYQQKASSKIGRKFKFGPHTVPTEFVMMRGPGGRGHAQVAITASNIGDEPSLANPDSTNPTSSSLRVSSEIKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNM1</accession>
    <name>A0A9P6MNM1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
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                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002001">
        <property type="protein sequence ID" value="KAG0008206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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            <begin position="976"/>
            <end position="1023"/>
        </location>
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        </location>
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        <location>
            <begin position="33"/>
            <end position="44"/>
        </location>
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        </location>
    </feature>
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        </location>
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        </location>
    </feature>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="631"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="976"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1013"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1023"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0008206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1023" mass="109044" checksum="CF3AEF0CE2A7F65F" modified="2023-09-13" version="1" fragment="single">MANTQMSSPTILPQEQSLQLLTPDQDSIQKLPQNHQQHQQQQQQDSSISLYQNQPYHHHHVQDQLDDMTREFLMQEMAADPNQQSQTLLQIPHACSSSSSSSSSTYVIDEELNIYDYIYAKQEGDDDEHDGDDHGHALSHEHGPDPNSSLSAILVTKDNLATFSPSASADANPINVFPHHHQSPVPSVPSPVLSAHSPSSPTLSTLSPSSPSSSLSSNVQHYDHSTSATAATVGVVAPSALTKGKDQDSDILGATHIKQECIDSTSLLDHNHSSYMDTSMDLYGSTHSPLLSSQSDLMPPPQDLFRVLMEELQTQASIQREKFFSATTGSGTGMDSVEFLFNGPQTQGQHQIQSQTHVQKSVPQFMMEPTAIPDMLSNNIKVGSAGQESSGSISEPSSTLAMNIENPSPPLDFTQAATPSHVSTELCSDNNDDVNMETADPEGDIPLSPIDSSSSSGSVTPELTSPVLQPCSPHTRTSPKAEVVRVAFTRLANQRSKPSDSDATAVQSSKVRKDSLPSIVFSITELSFQNALENNSSSSDNHNTRRRSAESIKEESLCPSVIAMKPAPRKRRKLSRDSDDRSPDASPRLSALPSPPSSVRTTPPLQPMTTDASSGVESLSLPPACGDSNDADISQPVTPTSPLLSKSVIKLELTASDEIMETVASEADAEQTEPLSAELASDPTKALPPNANNKRSWTSEEEALLLKLVENRTPIKDIAETLNRSVHSVRSRRQVLTDPGFVKGNGHAQPRRSKPDPSSKLPTYSQMAFLSLARLPELQGTLNDVASMVEKLFSRYLNRIPRTGHKNLQIWRAQISDALAHEKGHPRPRFESFGVKRGRQWVYRLTDFGKGVVNAMGSVDQIYEDLLKNNEAAGGGSNCGPDGESSGGAGAGLGQGNGYGYSYCPEAAPSPPPKSSSSDTSLESDDETNADNLAASNAIANAMAAMAAGLAAMTAVEDEKSAAVASAATNVLSAVPTATASTTASATTPTLATSKKVTGSLDPSKEKAGRASKSGNAVSATAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNW9</accession>
    <name>A0A9P6MNW9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RDH54</name>
        <name evidence="6" type="ORF">BGZ80_002913</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001745">
        <property type="protein sequence ID" value="KAG0008920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNW9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015616">
        <property type="term" value="F:DNA translocase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050496">
        <property type="entry name" value="SNF2_RAD54_helicase_repair"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45629:SF7">
        <property type="entry name" value="DNA EXCISION REPAIR PROTEIN ERCC-6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45629">
        <property type="entry name" value="SNF2/RAD54 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="4">
        <location>
            <begin position="65"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="5">
        <location>
            <begin position="257"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0008920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="569" mass="64235" checksum="B579C603CAD7B8D4" modified="2023-09-13" version="1">MHRRKKTGKKHKTWDGDGTATIGILVVRGTIGVLKDLEGKDIAKGIKVVAGIKDGDEISFGGKDIENWQMEFKKWLGVERLRVFAVDSKSTLTDFTLGKVYPVMIIGYEKLRIVQDELKNANFDIIICDEGHRLKTANIKTAQAIRSLPTKRRIILSGTPIQNDLCEFYSMIDFVNPGLFENYSTFKRVFEDPILTRLTSQFILRRTAQVNYEFLPQKSEVPKDESETQGLYNGVNSLLQSSGCDMKDPSISGKLSFVDALLKSIKHDTTERVVLVSNFTQALDLLEDICVRRNYGYFRLDGSTPTHKRQEFVDKFNAVSCQKYVFLLSAKSGGVGLNLIGASRLILFDIDWNPSVDLQAMARIHRDGQTRPVFIYRLLLSGTIEEKMYQRQLTKVGLSDALMDGKTSEMLNKFSMAELRDLFTLHEDEDCLTHSLLGCDCSIRSESHVDSINWDQEMMRNSSKAAKPIKSSIMDEMSVSLARKELEEWMHIDVSRWRKSLSNGVETGEGGDSDSSIMELSHKDRVLWRTIVGREEGVTEDEEKLSEREGGGDADAHSSAAFIFFKNVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPR8</accession>
    <name>A0A9P6MPR8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulatory protein sin3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">SIN3_1</name>
        <name evidence="5" type="ORF">BGZ80_002846</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001723">
        <property type="protein sequence ID" value="KAG0008994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPR8"/>
    <dbReference type="OrthoDB" id="10265969at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000118">
        <property type="term" value="C:histone deacetylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1160.11">
        <property type="entry name" value="Paired amphipathic helix"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003822">
        <property type="entry name" value="PAH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036600">
        <property type="entry name" value="PAH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039774">
        <property type="entry name" value="Sin3-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12346:SF0">
        <property type="entry name" value="SIN3A, ISOFORM G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12346">
        <property type="entry name" value="SIN3B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02671">
        <property type="entry name" value="PAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47762">
        <property type="entry name" value="PAH2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51477">
        <property type="entry name" value="PAH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0008994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="402" mass="44003" checksum="74288284F6725626" modified="2023-09-13" version="1">MNTPRDSTTDQDESNSSASFAHSLAVAPLDTASTLHNITLALNNGNNGNSNSSIPTDADTDSIMTNVTNAVQSSMAAMEQHPQQQPAESRMAVAELLVSLAQNSRSNEGSSLQDEGVAAFVSAATGNPPATQQSPIYRNAVDYVGSVKKAYESNPKVYTQFLSALEQYHGLTLPIDQLVRTVMTLFQDQPDLLLGFKEFLPESQGLLNQLVPPMMYSDYKAKTSAVTTTSTSTNSTIIPATLPTTSAVGTQQTVQQQGRSNTTFDNGHAAADFLSLIKERSQQEPDMYQHMITLLRKFQKDHSYANLYFYVSIVLRYHPHLLQRFHNFLPSVVSGVEVKEPRIISKAPPEDLVVSPDFIEAKDFVQTVKVYSEVSLIFWNHPDALAGFKNFISSVPPPPPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPX6</accession>
    <name>A0A9P6MPX6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Eukaryotic mitochondrial regulator protein-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_002256</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001551">
        <property type="protein sequence ID" value="KAG0009575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPX6"/>
    <dbReference type="OrthoDB" id="10052321at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021036">
        <property type="entry name" value="Ribosomal_mS45"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28158">
        <property type="entry name" value="37S RIBOSOMAL PROTEIN S35, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28158:SF1">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN MS45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12298">
        <property type="entry name" value="Bot1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0009575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="318" mass="35257" checksum="3C890D7A218D3D51" modified="2023-09-13" version="1">MASLSPATRALWSLKAAKAPMTSVPAFTSHRFIHTSRVTFEETKGNDATTPASTEATGEANEAVATGEEAEVAAEAAVGQKLPYRRKRFHMWLQSEGSRFAKPSFSGPNFVGDVPFPMNPLFKPTPPLSDTAKEEIYHFHRSDTAKWTPRQLGMKYNISIKRVEAILRLKHLEKEMISEGFIPQTNFTKGMEQLMGVKAVRSEAISEPLTDILPQVGSPKFEAVDEDKQFTAVDAAKVLKRRPLAEIKARQLEEEQKKPFKLVDSVKGVAKHEPLPTTPISRNVAESSPRFKFAILDTSAKTTLIREKDGTLVQVVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQB9</accession>
    <name>A0A9P6MQB9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidase M50B-like-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001465">
        <property type="protein sequence ID" value="KAG0009906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQB9"/>
    <dbReference type="OrthoDB" id="40823at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049500">
        <property type="entry name" value="Peptidase_M50B-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33979">
        <property type="entry name" value="OS02G0221600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33979:SF2">
        <property type="entry name" value="PEPTIDASE M50B-LIKE-DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13398">
        <property type="entry name" value="Peptidase_M50B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="144"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="218"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0009906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="255" mass="27462" checksum="1FD5A012FEC375E4" modified="2023-09-13" version="1">MAPINGSGSSQSILTPNKEQVTTLWFIGGYLLGILILWQMPILKHLLYPFKLVTIGLHEFGHACMACVSGGKVKSITVDPNLGGLTTYVGNRRTQCLALPAGYLGSSLLGGILVFCGFNVTASKGAAIMLILCLVLTMFWARNLLAFGICLFFAAIVGFLWWLDGGKYLKYFTLFLGVMSCIYSILEILDMLVLRKSNGSDAEQFAEKYGIFPAQGWGFIWLLVSLLFLVGAILAGLAAFKDDGSGSSSNSSNGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-06-18" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQE8</accession>
    <name>A0A9P6MQE8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">START domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_002391</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001589">
        <property type="protein sequence ID" value="KAG0009431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="196858at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00177">
        <property type="entry name" value="START"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002913">
        <property type="entry name" value="START_lipid-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051213">
        <property type="entry name" value="START_lipid_transfer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19308">
        <property type="entry name" value="PHOSPHATIDYLCHOLINE TRANSFER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19308:SF14">
        <property type="entry name" value="START DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01852">
        <property type="entry name" value="START"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00234">
        <property type="entry name" value="START"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50848">
        <property type="entry name" value="START"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="START" evidence="2">
        <location>
            <begin position="108"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="START" evidence="2">
        <location>
            <begin position="664"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="272"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="402"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="550"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="969"/>
            <end position="1076"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1238"/>
            <end position="1298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="403"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="439"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="508"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="973"/>
            <end position="1003"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1015"/>
            <end position="1030"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1032"/>
            <end position="1044"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1257"/>
            <end position="1267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0009431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1452" mass="157177" checksum="0A334A7A96F7AF26" modified="2023-09-13" version="1">MVVPPFHEYPLSGDESDNNFNQMEHLRSQFYTADPQKKTKEYHIEQATQAIELLKGATRPNGWKKIDKHKSGCLVYQSMSPATIPTHSDVKSPAYKGEHIIKGYKAQDVYAIVNVRKLWDDWYDEISCVETYDESTTLMYMVMKGTLSSKTRDIALVERVERASNGTIYYASCSVESNKIPRASGKVRAEISLTGWVIEPLPSNPPITKITYVIQTDLLSRLPKFIAKRSMAKRALAITTVESYLQKNGAPSMATTGTRTLARQRSFSEPLKLDQFLLPEDSDNEDNGEDGDDDDYDDDEIEAAVRSPKGPIKSRKDLQYMDDSAESEEEELEMEIRNAPRQRVTAKTASAAKSNAPPTVNPLFSKEFMENNAFLQDPNLFGDSSFLFGTGSNYFEDKKKQEVAPAAPAAPTAPAVPAVSSATRPSPPAPKQQVQQEQAQERPKEKKEKAGRPRLPSNTSKTLLPEPDSRKPPSNKRISIPVVAPKSEARIKQSSQNGSSVHLHVPESTPAGATVTSSPPPTPPASINGKDATSDSDAAVQNVKVVPRIPKTAPAPAPTSESTESTSLAMSSLVMKPPSALMEANSRHHNNILIRNGFVPRHSHAVPIRGNPNVSLQSLIRPSGPSSTVSTSIKRHSTALSVDSSRSSTNMFTPLMVLPHRHSETARKALAMFKVLASSPEDRWRAISSENGFKSYSRVISGAGLPMLRGEGTITGGWTVEQINAVIESSGCRQVWDERFENMSIAETFNHNEYLFHVSLLGMGSMTGRDLAGVTIIDRDPQTSSLYNVSTSVLDPTIPEDPGRIRAMLELSGWSLRPTFDGQGNTLSVSVTFVIQIDIRGNLPSSIVKTMTSSMSTAVSRLNQFINKSGYPPFASHISGTRLMDTFEPKTGFYELCYKAAPGWTEVRIGRKVYKEGYDFFIKPDDPSVKVEMAPDFGGVRVWTTLDHEGQSIIAQVSRKGQNVIAPETEVVEEQKNETEAEAVKGSFKDGRSRQSEIEEDLRYSTPTGRKRRSSSFTTPTQVSLSSARPDSQASIASKASQSSDRGRSRGRTTRPLVTLPANTPPPPLPRRSSSLGRLSIPISEYFPGADAPPVPAINSPSETNGVLISRPISESLGSPTLGFFHVPVVPVVAGTVAASSDAAVSSTAPVSPAPVASPTSPMESITAVLSEEATAKPVADAEPESTLTIEAAASNVESVSVMTEVETIDIPTSPIPVAIDKKPIDKKIDEVVSSLSSQVSPTSTPVPSPMAMSFSRRGSSLLSTPVSEPATPPMKATPTPSQKMTPPSAMLNGATKKREARVTFSLDTIDKSTDDTIRGGLKINNKGRTVQIVTPALHQQQKAIVEPGSDGSSDEAEFVEARDELSDDELELAFVLMSVGSWPSLLSTSSSAASAMELEGKQQGEEMVAASLKAIETGFRMVTTGTPTEVKIAIVFLLLVYYAGRLSSLIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQN7</accession>
    <name>A0A9P6MQN7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_001696</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001393">
        <property type="protein sequence ID" value="KAG0010191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQN7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050562">
        <property type="entry name" value="FAD_mOase_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356:SF2">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356">
        <property type="entry name" value="FAD-DEPENDENT MONOOXYGENASE ASQG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="1"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="269"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="424"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="440"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0010191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="450" mass="50205" checksum="46FD3574ECD98109" modified="2023-09-13" version="1">MIVGAGIAGLFLAILLDRINVPYEIYERSSETRPFGGIVSLNPCVLAVLEQLGLFEEIQKAAYINRIFSIYTGNMEKIARLEGDDKYTETVGYDIHLLSRPEFYNILLSRVPAHKIHYKKKVMSIAHNKEGAMIRCSDGTTYHGDILVGADGGNSGVRQGLYKLMRNYGQLPESDAKGLGKCDICMVGTTDSLDPEKYPGITEPVSISYQVIGEKIPYTWNCITVADNKICWLVVKQIGSAESETERLRNSEWGPESNEAMIKEVRDFRIPTGTLGDLIDATPKERISRMFLEGRLFGTWTHGRTVLIGDACHKLPPSSGQGAVNAMQDAVILANCIYDLKSVAEVDVIEALRDFKEQRFPHVKDQFKASQTSAKLIFGQTTFERILRKVVLGYMPKSILLKSMNKELSYRPQASFLPLAPKRGTMDILPQKPSKRYQEEQNSAGTPTPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRI6</accession>
    <name>A0A9P6MRI6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tail specific protease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_000940</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001207">
        <property type="protein sequence ID" value="KAG0011109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRI6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052766">
        <property type="entry name" value="S41A_metabolite_peptidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37049">
        <property type="entry name" value="PEPTIDASE S41 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37049:SF4">
        <property type="entry name" value="RHODANESE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040139548" description="Tail specific protease domain-containing protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="389"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="94"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="389"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0011109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="754" mass="82106" checksum="7116DFEE1B0388A4" modified="2023-09-13" version="1">MKFTSIISLAIALCVVSTNAAPVAANAHTTTTTKAHTTTKAHTTTKAHTTTKAHKTTTTKAHKTTTTKAHKATTTKAHTTTKAHTTTKAHTTTKAHTTTKAATTTTKSAAPKPTTSSTPTPKDPCSELAKAKDSSSVLSFNNVQDCYRAQSFKSDVAEKVLTSLENLIGNFYVFVDQAKASSSAPFKTPKVDLMAGLKKIRATKWKNDYDFNMALTYLTFSANDGHLAYRSDCYNTATFTQPISLYAPVVNGVQSVRVFYADDTQKGVPKTGLVDCAVTEIDGVPALKAVQDFTDRISAISKDPGVRLNDAFASTSWYNEWLISPGGFSKRWEVPAKASMDYTIQCASGAAQKITVPWIVKPSDTFMFNTFTDTKTYWTAQCLAPLSPYNSNSRNQNNGKNGTNDSLPGNRYNVAPATTLYRERGTIKIPGGGKNGRGSTALTITKANEVMVTATTAFYRLKNSNACVAVVASEEAAYFKFDPSDYLQFIEGLQTLRDGGCKKLIFDMTNNGGGSVDFAYFINALFFPKDKPYFVEDLRSNKFVQGAAKAAAKLSSSSSVFDARGYVSMATGKPFKDATMFTKGVNYKRGGTTQTYSQKNYFEYYWPFLPLAKNNTLPWKASDMAIVTNGFCGSACTMIATRFNVVHKVKTYAVGGIHKTPLSYFSFPGGFVMDNESIVSDLRRLGYKGTNAPSNFVVKSTANIAVGEIYATENSTIPLEYDSKYFAANVHFDQDAVSARHPDNIWVKIAADFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRR6</accession>
    <name>A0A9P6MRR6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">FAD-binding FR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BGZ80_001650</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001381">
        <property type="protein sequence ID" value="KAG0010247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRR6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043020">
        <property type="term" value="C:NADPH oxidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016175">
        <property type="term" value="F:superoxide-generating NAD(P)H oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:monoatomic ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042554">
        <property type="term" value="P:superoxide anion generation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.80:FF:000004">
        <property type="entry name" value="NADPH oxidase isoform 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050369">
        <property type="entry name" value="RBOH/FRE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972">
        <property type="entry name" value="NADPH OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972:SF153">
        <property type="entry name" value="SUPEROXIDE-GENERATING NADPH OXIDASE HEAVY CHAIN SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00052">
        <property type="entry name" value="Ferric_Reductase_Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01168">
        <property type="entry name" value="Ferric_reductase_subgroup_(FRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01169">
        <property type="entry name" value="NADPH_oxidase_subgroup_(NOX)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0249">Electron transport</keyword>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="106"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="149"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="193"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="234"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="262"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="13">
        <location>
            <begin position="320"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0010247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="607" mass="69804" checksum="260D7374581977E2" modified="2023-09-13" version="1">MGTSSGYDYDQTRANTLANRGTSDPQSHITKQRPVTAYSALIPPPSPTYFRLQEMGSPTRSNFPPQQTRGELDHLRRLEPAPPQVEENISWIQKISIWMINEGNRVIFFGVWILVHIGLFGLAFFNYFYSDNFITTRDIVGVTLPMARGSALVLHVDAGVILLPVCRTLISWLRSTPLNRIVPFDKAVTFHKAIAWSIVFFSFLHTFSHYVNFYKLAKTGKYNFWNLMFVSGPGWTGHIMLVALVAIVVTALPSVRTKKFEVFWYWHHLFLIFFFFFSFHGAFCLLTPDRPPYCKDISSFWKYWVSSGFIYLCERIAREWRAQQKTVISRVILHPSKVVEIQIKKENCHALAGQYIFLCCPEVSLWQWHPFTLTSAPEEDYISVHIRVVGDFTKELSKKLGCDTEGVGEWEENLGDRNGLVTVLPRIMIDGPFGAASEDVFKFEVTVLVGAGIGVTPFASVLKSIWYRVNYPTKPTKLHKVYFFWICRDKESFEWFQSLLLALESQDLNQFIEIHTFLTGRLRHSEVGNLMINEDSAFADTVTGLRARTRFGRPNLDMEFDRIRGNHPDTDIGVFFCGPKRMGRQLHTCCTKFSGSGTSFFWHKENF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRV4</accession>
    <name>A0A9P6MRV4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_001286</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001291">
        <property type="protein sequence ID" value="KAG0010653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRV4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0010653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="52" mass="5996" checksum="FDE049A338DA963F" modified="2023-09-13" version="1">MDYDRVLVLEQGRVVEFDSPINLITNPTSRFRDMVEKSGEVDALFEMAARAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSD4</accession>
    <name>A0A9P6MSD4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_000300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001059">
        <property type="protein sequence ID" value="KAG0011962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSD4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="42"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="107"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0011962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="194" mass="21910" checksum="4FBE32D62FAB50A4" modified="2023-09-13" version="1" fragment="single">RSQQEVPMRGPSRHRRDDHDDDDDEDTDLSQYGQRGHGGQQYGYSKGQQRQQSQQQQQQQHQQQQHYRGGQQQFANNSGYEPFPSSTHGSGNNGKYQGSLDSLMMENNNSSNNGTINNIGRYSQSANMVGNTSLQEEDEEEHEDTLVDNTMMRSMSGQGSNQFLPHQKQQQHQGGKFHGNSMMASFPNAQSIQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSJ1</accession>
    <name>A0A9P6MSJ1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Plectin/eS10 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_000543</name>
        <name evidence="9" type="ORF">BGZ80_008438</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic ribosomal protein eS10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001111">
        <property type="protein sequence ID" value="KAG0011642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JAAAID010000457">
        <property type="protein sequence ID" value="KAG0017293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSJ1"/>
    <dbReference type="OrthoDB" id="5211809at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000025">
        <property type="entry name" value="40S ribosomal protein S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005326">
        <property type="entry name" value="Plectin_eS10_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037447">
        <property type="entry name" value="Ribosomal_eS10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12146">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12146:SF0">
        <property type="entry name" value="RIBOSOMAL PROTEIN S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03501">
        <property type="entry name" value="S10_plectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Plectin/eS10 N-terminal" evidence="7">
        <location>
            <begin position="3"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="91"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="101"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0011642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0017293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="151" mass="17545" checksum="DFFD042A8E8E3E85" modified="2023-09-13" version="1">MLIPKQNRKLIYEALFKDGVLVAKKDFNAAKHDEIDVPNLQVIKALQSLDSKQFVKTQFSWQYYYYTLTDAGIEYLREYLHLPSEIFPATFKKTARPSAPRRAERPEGAYRPRGDREDYRRRDDGEKKEGASGDYKPEFRSGLGRGRPAPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTB7</accession>
    <name>A0A9P6MTB7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_000377</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001076">
        <property type="protein sequence ID" value="KAG0011859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTB7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040203426" evidence="1">
        <location>
            <begin position="22"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0011859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="131" mass="14155" checksum="C9083E72D2981745" modified="2023-09-13" version="1">MKFFTAIVALVAAAVVTVVDAQVIYADCDLGSDLTINTSSFYPYPLCVGQNVCVTGAGTSSAPVTAPSTLSIVGKYFGTHLHRLRGPPRPLGYCGTRLPCPTIRELHHRLRPDQVLCSHRRKLMKSNEAVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTH8</accession>
    <name>A0A9P6MTH8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">GET complex subunit get1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7 11" type="primary">GET1</name>
        <name evidence="11" type="ORF">BGZ80_000247</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the WRB/GET1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001045">
        <property type="protein sequence ID" value="KAG0012037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTH8"/>
    <dbReference type="OrthoDB" id="69461at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043529">
        <property type="term" value="C:GET complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043495">
        <property type="term" value="F:protein-membrane adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071816">
        <property type="term" value="P:tail-anchored membrane protein insertion into ER membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.660">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03113">
        <property type="entry name" value="Get1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028945">
        <property type="entry name" value="Get1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027538">
        <property type="entry name" value="Get1_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029012">
        <property type="entry name" value="Helix_hairpin_bin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42650:SF1">
        <property type="entry name" value="GUIDED ENTRY OF TAIL-ANCHORED PROTEINS FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42650">
        <property type="entry name" value="TAIL-ANCHORED PROTEIN INSERTION RECEPTOR WRB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04420">
        <property type="entry name" value="CHD5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040337007" evidence="10">
        <location>
            <begin position="24"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="topological domain" description="Lumenal" evidence="7">
        <location>
            <begin position="1"/>
            <end position="3"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="105"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="topological domain" description="Cytoplasmic" evidence="7">
        <location>
            <begin position="169"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="262"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="276"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0012037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="303" mass="32897" checksum="D6F5EA59E5C81E05" modified="2023-09-13" version="1">MQLAFGVLLVVLLTELINLVGKAHVTTLAYDIYLKVVNKETMVKQRQLKKEVLTLKNDLSRTSSQDEFAKWAKLRRKMDSKIAELDKLTSELHLTKASFEIKFKSLLWFITNGIQFFMITWFRRSPMFYLPHGWFGPAEHVLALPFAERGAVSISIWFYFCRKTILLFTSNLAEFVPAVRAWKQEQPSESSSNPFAAFANMASMASAAGGSGPGSPGSMGGNPFAAMGGMGGMDFGASGMEGMAGMDTANMFGPGSPFAAMFGQTLSPNMGGGSGASSPTPSRSSSVRGAGNLGRGEDRRRKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTR1</accession>
    <name>A0A9P6MTR1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cross-pathway control WD-repeat protein cpc2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">CPC2_2</name>
        <name evidence="5" type="ORF">BGZ80_011104</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000851">
        <property type="protein sequence ID" value="KAG0013405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTR1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045182">
        <property type="term" value="F:translation regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000615">
        <property type="entry name" value="Receptor for activated C kinase 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045223">
        <property type="entry name" value="RACK1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19868">
        <property type="entry name" value="RECEPTOR FOR ACTIVATED PROTEIN KINASE C RACK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="12"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="61"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="103"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="157"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="259"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0013405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="285" mass="31433" checksum="43F98698E0D6426F" modified="2023-09-13" version="1">MSSDSLAYRGQLVGHRDWVTAIATTAEAPDMLLTSSRDKSIIVWNLVRDDEGNFGVPRKSLHGHNSAVQDVVISSDGQFALSASWDKTLRLWDLNTGLTTRRFVGHTNDVLSVSFSADNRQIVSGSRDKTIKLWNTLGWDKIVKVWELTKCKLRSNHIGHTGYINTVTVSPDGSLCASGGRDGITMLWDLNEGKHLYSLEGKGDDIINALVFSPNRYWLCAATSSCIKIWDLESKSVVDELKPEFTNVGKKSNPPQAVSLAWSADGQTLFAGYQDGLVRVWSVGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MU34</accession>
    <name>A0A9P6MU34_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Glycerol channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">FPS1</name>
        <name evidence="9" type="ORF">BGZ80_011461</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000923">
        <property type="protein sequence ID" value="KAG0012870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MU34"/>
    <dbReference type="OrthoDB" id="3222at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015254">
        <property type="term" value="F:glycerol channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015250">
        <property type="term" value="F:water channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00333">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="entry name" value="Glycerol uptake facilitator protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050363">
        <property type="entry name" value="MIP/Aquaporin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022357">
        <property type="entry name" value="MIP_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00861">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43829">
        <property type="entry name" value="AQUAPORIN OR AQUAGLYCEROPORIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43829:SF9">
        <property type="entry name" value="AQUAPORIN-9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02019">
        <property type="entry name" value="AQUAPORIN7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="Aquaporin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00221">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="122"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="165"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="199"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="252"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0012870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="284" mass="30279" checksum="CDD980877A2D1686" modified="2023-09-13" version="1">MPHHSHSHGHETDPLLERVERGVVHAQYEARSKWAGVRHKFRKAFAEFLGTAILVAFGSGAIAQLVFSPNNSWFTMSLGWGLGLTFGIYVAGGVSGAHLNPAVTLAQAIFRGFSWAELPIYWIAQFAGAFAGALIVYITNYSAIQAADPSATVGIFITGLQTKDVTTTAAFIAEFLGTALLVLVILSTSDKGNTPAGNTQPLIIGLSLAAIGTSFGYQTGFALNPARDLAPRLFTALFGWGFGVFTRQGWYFWVPIVAPFLGAIGGAFTYDLLVYSSGPSPLNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MU87</accession>
    <name>A0A9P6MU87_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Phospho-2-dehydro-3-deoxyheptonate aldolase</fullName>
            <ecNumber evidence="8">2.5.1.54</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ARO4</name>
        <name evidence="10" type="ORF">BGZ80_010788</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>D-erythrose 4-phosphate + phosphoenolpyruvate + H2O = 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14717"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16897"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="2.5.1.54"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 1/7.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the class-I DAHP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.54" evidence="8"/>
    <dbReference type="EMBL" id="JAAAID010000791">
        <property type="protein sequence ID" value="KAG0013878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MU87"/>
    <dbReference type="OrthoDB" id="4699125at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003849">
        <property type="term" value="F:3-deoxy-7-phosphoheptulonate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000005">
        <property type="entry name" value="Phospho-2-dehydro-3-deoxyheptonate aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006218">
        <property type="entry name" value="DAHP1/KDSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006219">
        <property type="entry name" value="DAHP_synth_1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00034">
        <property type="entry name" value="aroFGH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009395">
        <property type="entry name" value="PRK12755.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009396">
        <property type="entry name" value="PRK12756.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21225">
        <property type="entry name" value="PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE DAHP SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21225:SF12">
        <property type="entry name" value="PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE, TYROSINE-INHIBITED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00793">
        <property type="entry name" value="DAHP_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001361">
        <property type="entry name" value="DAHP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAHP synthetase I/KDSA" evidence="9">
        <location>
            <begin position="66"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR001361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0013878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="377" mass="41000" checksum="93E2DC3AC889FF1B" modified="2023-09-13" version="1">MSPSTTTTSRPESPVPLMHSKEEIAPEFMEDLRVTGYSPLLPPQIIQEEHPMSEVSKKVVSLARQQAAKILRGEDDRLIVIVGPCSIHDPKAAIEYATRLKPVADQLSGEILVIMRAYFEKPRTTVGWKGLINDPDIDGTFQINKGLRIARSLLNQLTDMGVPVGCELLDTISPQFLADLISWGAIGARTTESQLHRELASGVSFPLGFKNGTDGNIGIAVDAIRAAAKPHHFLGVTKQGLAAITNTRGNELCHLILRGGNDGPNYEKAYIEKTREGLAKAKLPEVIMVDCSHGNSRKQHKNQVSVSADLANQIRAGDKSIVGLMIESNLVEGRQDVGPEGKDALTYGQSITDACVSWDDTVKMLEDLAEAVRVRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUG5</accession>
    <name>A0A9P6MUG5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Citrate (Si)-synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">CIT1_3</name>
        <name evidence="1" type="ORF">BGZ80_010807</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000794">
        <property type="protein sequence ID" value="KAG0013848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUG5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.580.10">
        <property type="entry name" value="Citrate Synthase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016142">
        <property type="entry name" value="Citrate_synth-like_lrg_a-sub"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0013848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="77" mass="8411" checksum="5DEB0A5EFA07D666" modified="2023-09-13" version="1" fragment="single">MASLRAAFSLPGLAKVATRHNTFAATAIRAYSTKPQGLKDRLRELIPEKREEVKQVKAEFGSKVLGETTVDMAYGGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUX4</accession>
    <name>A0A9P6MUX4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Elongation of fatty acids protein</fullName>
            <ecNumber evidence="10">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_010388</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>an acyl-CoA + malonyl-CoA + H(+) = a 3-oxoacyl-CoA + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:50252"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:50253"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the ELO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="10"/>
    <dbReference type="EMBL" id="JAAAID010000718">
        <property type="protein sequence ID" value="KAG0014522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUX4"/>
    <dbReference type="OrthoDB" id="10259681at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009922">
        <property type="term" value="F:fatty acid elongase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034625">
        <property type="term" value="P:fatty acid elongation, monounsaturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034626">
        <property type="term" value="P:fatty acid elongation, polyunsaturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019367">
        <property type="term" value="P:fatty acid elongation, saturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030148">
        <property type="term" value="P:sphingolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042761">
        <property type="term" value="P:very long-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002076">
        <property type="entry name" value="ELO_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157:SF169">
        <property type="entry name" value="ELONGATION OF FATTY ACIDS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157">
        <property type="entry name" value="FATTY ACID ACYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01151">
        <property type="entry name" value="ELO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5 10" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7 10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="66"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="121"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="149"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="172"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="205"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="238"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0014522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="275" mass="31045" checksum="670CDE4EDB55345E" modified="2023-09-13" version="1">MEAGPMPAGIPFPEYYDFFMHWKTPLAIAATYTIAVSLFNPKVGKVSRVVAKSTNAKPAEKTESGAAMTAFVFVHNLLLCIYSGITFYNMFPAMINNFRTHGIHDAFCDTDKSLWNNALGYWGYLFYLSKFYEVIDTIIIILKGRRSSLLQTYHHAGAMITMWSGINYQATPIWIFVVFNSFIHTIMYCYYACTCIGLHPPGKKYLTTMQISQFLIGTSLAISYLFVPGCIRTPGAQMAVWINVGYLFPLTYLFVDFAKRTYSKRSAAAAQKKAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVA8</accession>
    <name>A0A9P6MVA8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_010247</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000695">
        <property type="protein sequence ID" value="KAG0014749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVA8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052394">
        <property type="entry name" value="LRR-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24114:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24114">
        <property type="entry name" value="LEUCINE RICH REPEAT FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0014749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="898" mass="100892" checksum="B7E7D8E535A03263" modified="2023-09-13" version="1">MSTPMSTNNTMNIEPLRTPFPSILPQGATEDRASNERGSQANFHTWSPGSADFSIVGDVPADRQDPLPKSGTQKRSETVTDTELSLIARVFNFFEEAPEDVCAKEWWKSLGKRPRDRLSRVTGIGTRTCDRAIHLADSGSLKKSATMKTGRPKKPMDKTVEDTINQVVSETNKQGIPNSSRLLSNEFRKEHNILCSPRTVRRDLRKLEMFWGKGIRQNIQHDAPQNVAYRNKYLLERLKNLRWVKSGGVVREPGRKPLLVIFAAFVVWYDEGRSELRSSFVNNSVHIWPAIGKAHTKQASNRKSAYDAAMWNDVPEEIRNAGIVADLSEDYHDNFNGELFDKLFEKLCDNLANMGLRGCNIHLDGASYHFHKKHQRPDPKKSKVADLREWLTSNGYDLPPAARGEGFQPNGKELMSRIKTILSELDYSIYSIAAEHGGHRICKTPPYHYELQPIEKIWAVVKNAVAAQATGNMKALQLKQTLIGYFFEIPMFIFISLWNKNIEISKAYIEAGHEAQEDVDCGQWCELEEGDVGEAYEIQYPTNDIWLRYLREVEVVDMLNALTLKSVDVGEDFDGAQLVEDEEDEEEDSTSIAGYVVPALASLKVVEMVDSVQQEVESVTAKIDYSLEYINAQLSKVQASSSGDLTNTNGPQAAVTQQDLKNYLNNVEGLEGSEFAAAEFYDAITKARGVLELSVKLDWVKHYTDFVNLKDMIPTSNIRSIKVDLTSRTDRKLDFNIREHKRYDPLVEIMRLPSIQSFEVLNVYPDFFKNIQLAPSLVDVDMAKLKSLISLAPNFSSLSLQTNTELSLALFVVFKTNSTLTTLDLRYNSIGFSGVKALSEALKVNSTLTTLNLQSNSIGDNGAQALSEALKNNSTLTILNLQSNLIKHNRAQERVSSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVF2</accession>
    <name>A0A9P6MVF2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tetrapyrrole methylase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_009976</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000649">
        <property type="protein sequence ID" value="KAG0015207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVF2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004851">
        <property type="term" value="F:uroporphyrin-III C-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019354">
        <property type="term" value="P:siroheme biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11642">
        <property type="entry name" value="SUMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.950.10:FF:000005">
        <property type="entry name" value="Uroporphyrin-III c-methyltransferase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="entry name" value="Cobalt-precorrin-4 Transmethylase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="entry name" value="Methyltransferase, Cobalt-precorrin-4 Transmethylase, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006366">
        <property type="entry name" value="CobA/CysG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050161">
        <property type="entry name" value="Siro_Cobalamin_biosynth"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45790">
        <property type="entry name" value="SIROHEME SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45790:SF6">
        <property type="entry name" value="UROPORPHYRINOGEN-III C-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="Tetrapyrrole methylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Tetrapyrrole methylase" evidence="4">
        <location>
            <begin position="48"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Tetrapyrrole methylase" evidence="4">
        <location>
            <begin position="167"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0015207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="317" mass="33858" checksum="D10E38CE1066C0DE" modified="2023-09-13" version="1" fragment="single">MSNPYNSPPASPKNSEAVLLSTRATNTNSLSQYSSSNDTSRPKGEIKLIGAGPGDPDLLTLAAYKSITSWADIVLADKLVSKEILALISCTLFIANKDKGCQASGQQELFERAAQALKEGKRVVRLKQGGNPSSLASIAVCIFTSLYVGLGNRFINSSSSLRSGLLDPFIFGRGGEEFLFFRRLGYEPTIVPGLSSSISGPLLANVPLTHRGTASQFLVCTGTGSQDVIPEMPPYVAHRTTVFLMALHHLEALIQSLVIVGYPRELPVAIVERASAKDQRCIHATIGTVVQVVKEVGYNPPGILVAGWACEVLSQDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVI1</accession>
    <name>A0A9P6MVI1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_010119</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000670">
        <property type="protein sequence ID" value="KAG0014995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVI1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990234">
        <property type="term" value="C:transferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.80">
        <property type="entry name" value="E3 ubiquitin-protein ligase SopA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847:SF637">
        <property type="entry name" value="WD REPEAT DOMAIN 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25173">
        <property type="entry name" value="Beta-prop_WDR3_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="16"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141571">
        <property type="entry name" value="Pentapeptide repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="14"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="311"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="353"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="395"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="437"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="479"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="521"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="560"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="602"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="644"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="686"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="728"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="770"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="812"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="854"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="900"/>
            <end position="936"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0014995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="995" mass="109860" checksum="898CA7ECDE2BF51F" modified="2023-09-13" version="1">MELNPYDRETFKQMMDFGFQEQGITYLKELVTAIYEHQNGNPVVNYSSRLDRKTWKEAFFSERDGSHLLREATPLTRNGDQYRFIHKSLLEYGLSLAVFGPSKRNEEDIEATPSMPRRGSTSSVLSFEVPSSTESAAAADDNPLLDSPLGKRNLVGERSVLQFLTERAQQEAVFKDQLLSVIERSKSDKTVRIAAANAITILVRAGVQFNNADLRNIQIPGADMSFGMFDSAQLEGADLRKVNLRSVWMRQANLKGAQMKGVQFGELPFLKEDSEVYCGAYSPDGKIYAAGLGSGNISLYETSSWSRVKKLKGHYDIISSLSFSTTGSQIASGSFDSTVRLWDVESGECVHTLQGHSDRVWCVVYSPRGDRIASGSRDSSMRLWDVDTGECVYNLQGHRRGFKSFVFSPKGDRIASGGWDSTVRLWDVDTGKCIHTMDGHSNYVLSVAYSPNGDQIASGSDDKEVRLWNVDTGECVQTLQGHSGYVRSVLYSSEGSRIVSGSEDKTIRLWDVDTGECVRILKGHSGSVESVVYSPRGDRIASGSRDSTVRLWDVDTGECVHTLQGHVNFVVYSPKGDQITSGSPNNTVRLWDVDIGECTHTLQGHSSGVKSVVYSPRGDRIASGSSDNTVRLWDVDTGECVHTLQGHSFFVDSVAYSPKGDRIASGSYDKTVRLWDVDAGECVHTLQGHGGYVLNAVFSPKGDRIASGSHDKTLRVWDVDTGECVHTLQGHSSFVRSVTYSLKGDRIASGSDDMTVRLWDVDTGKCVHTLQGHSSFVRSVAYSPKRNQIASGSEDKTVRLWDVDTGECVYSLQGHSHVVCSVVYSPKGDQVASGSEDKTVRLWNVETGECIHTLQGHSGCVSNVVYSPKGQIASISWDMTVKLWDVETGHCLVTIPCNGVSSVAWESNFEPQYLVTGSHDKSVRRWRITKEEVEHRAVLCWSSSHEVLTVHDLSFDDVQDLSRMNQELLIQRGASVPIPLLSDRESVDKSNLGRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWY9</accession>
    <name>A0A9P6MWY9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Chaps-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_009589</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000589">
        <property type="protein sequence ID" value="KAG0015841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWY9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034044">
        <property type="term" value="C:exomer complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006893">
        <property type="term" value="P:Golgi to plasma membrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015374">
        <property type="entry name" value="ChAPs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31975">
        <property type="entry name" value="BUD SITE SELECTION PROTEIN 7-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31975:SF1">
        <property type="entry name" value="BUD SITE SELECTION PROTEIN 7-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09295">
        <property type="entry name" value="ChAPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="383"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="426"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="442"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="465"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0015841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="710" mass="81004" checksum="DA4EF3735B7AC383" modified="2023-09-13" version="1">MGENLRDIPEFIERELGESLHARTDALGTFKELGAPDLCHIIKVNVKPNVKETSSYHYVSGIDASSSASLAAYLNSLTYAIDESNAWFSKGVQWRIRSGVYCCYNAFSRVDVRVEVKIPGGVESYAVNVRGERQEATAAIWQETFITAMLRSILYSDDANYRIPGFRKLDPIPDVDAEKRFFEAAEQLFFKGWLLGSNPEIQVPTIVNNHLTAAIMKYCQESFRYDLAARFFERLFKREAEVASLLAQAYIGSDEELKAINVLYEALKQFPQSYALLHVQADFLRGKGKLEMALRLAKQAVNCAPSEFVTWAKLTEVYIDLGDYESTDLALLRLPAPSLRGTYASAYNLLTRLVSKIGWDELLRCRSLVFVMEEEYRMQKEAEESIRKGSHARAMSRDETVPEEVPARDQLLSPNGTPIPIIKISTESEREREREQEEAEEEARAKAVEVAAEKTVDENADQSMEDIKLDDLSLSDKQDETDSTQAKTEEDNETSQEHEHVPINGKQIEKPSIAAASDDEDNEDEEVELSFSFSNKRLCDRWLDNLFMVLYEDLRQYTIWRAEIQHFRSVQAPYRKSGTDWEIYGDLATRLHHREEAKDAYQRCVDQKFSAKALVRLLEIYADEGQLLKAMEVSIKLCVYQERWYQETVFPTAIAHNLNKLIQSEGLEKVQNTLIALNTSPAVYKLMSRYLTRAKTFEVPGSSVKSRIDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXE4</accession>
    <name>A0A9P6MXE4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphatidylglycerol/phosphatidylinositol transfer protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_008285</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the intermembrane transfer of phosphatidylglycerol and phosphatidylinositol.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NPC2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000444">
        <property type="protein sequence ID" value="KAG0017443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXE4"/>
    <dbReference type="OrthoDB" id="6409159at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032934">
        <property type="term" value="F:sterol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015918">
        <property type="term" value="P:sterol transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003172">
        <property type="entry name" value="ML_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039670">
        <property type="entry name" value="NPC2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11306">
        <property type="entry name" value="NIEMANN PICK TYPE C2 PROTEIN NPC2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11306:SF0">
        <property type="entry name" value="PHOSPHATIDYLGLYCEROL_PHOSPHATIDYLINOSITOL TRANSFER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02221">
        <property type="entry name" value="E1_DerP2_DerF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00737">
        <property type="entry name" value="ML"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040313554" description="Phosphatidylglycerol/phosphatidylinositol transfer protein" evidence="8">
        <location>
            <begin position="19"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="MD-2-related lipid-recognition" evidence="9">
        <location>
            <begin position="26"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0017443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="144" mass="14853" checksum="377FCC4A13712207" modified="2023-09-13" version="1">MKFSTVFATFSSILLASAVTGAKTKFGSCGSSDVMTFKSAQVPAVKAGEKACGSVTGSLSQPLTGGQVTITATYMGFTVHQETKDVCADSACPLDEGKHTILVCFNVPDNTPDNLTIDVKVSATNQNSAALFCAEGMVVTQGKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MY12</accession>
    <name>A0A9P6MY12_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_008571</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000469">
        <property type="protein sequence ID" value="KAG0017149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MY12"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045913">
        <property type="entry name" value="TBC20/Gyp8-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20913:SF7">
        <property type="entry name" value="RE60063P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20913">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER 20/GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0017149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="168" mass="18939" checksum="230B8164041D54CC" modified="2023-09-13" version="1">MSVYLAAAVVMSRREELFEVECDNAMVHSFLTKFPKNADLELIISHAHKLYVTYPPEALQNRAQSWLDGNSCVNTFNKSNTRLYDDNDEKVYSTPFDFGPIDNLLGKPRVKRTAESSALSKYPPNAIRLYRRNMVTMVAFSAASVGTAALLLLNSALFREWLSSTGHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MY55</accession>
    <name>A0A9P6MY55_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">SPX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_008647</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000476">
        <property type="protein sequence ID" value="KAG0017061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MY55"/>
    <dbReference type="OrthoDB" id="5588846at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06251">
        <property type="entry name" value="M14_ASTE_ASPA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055438">
        <property type="entry name" value="AstE_AspA_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053138">
        <property type="entry name" value="N-alpha-Ac-DABA_deacetylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37326">
        <property type="entry name" value="BLL3975 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37326:SF1">
        <property type="entry name" value="BLL3975 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24827">
        <property type="entry name" value="AstE_AspA_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03105">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="SPX" evidence="6">
        <location>
            <begin position="1"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="46"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="171"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="72"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="171"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="185"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0017061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="656" mass="72282" checksum="F137B3D2436D1EAE" modified="2023-09-13" version="1">MKFAKQLGLRSIPSWAPYYLDYKSLKGYIKTSFKGLAGPLESLESVDHEGQEHCSQMETNGAEPKITISEPPESSDSGPITSDQEASKEKNASDDAAYEASVNIAVEGFKALLWAELEKVNARYEAQERVAGVNLERLNASYLLEFSQTNITGFKKIIKKFDKHYRGCQSTSQLSSSASSTPLSEQGNDGTDSANTITYPAPTAVDPDAPSTLSMFSNLSIHGRGTPTIYLPNGYLEPASSLQPQEPLIRNMSSPGSSKSVFYHNYYGGVSALSLELWKMVIERTFAKSEKDERLLTEARALWRKRTPVVPEHVSPLLLNVDPKDYPVWDDLDLESLPSGRLTRLWIVLAESAMSTPIKVPVLVAKGVRPGPVVGLTAALHGNELNGIPLTHRLVLHEIQCQALHGIVVAVPVANVPGYLAGQRGFSDGTDLNRLMPGKKDGSTSQVYSYNLMTRIIRHFTHLIDLHTASKGRVNSLYVRANMQNSTTRHMARLQNPQIIVHNTSPDGSLRGAAMQQYNIPAITVEIGDPSRFQKRFVKNAILGVTNILSHLKMIEDDHEVQDYEPVVCAKSYWIFTKGGGILNVLPDVNTWVRKGELIATLHNIFGEEEHRYFAPEDGVVVGKSVDPVCQSGCRILHLGVVSDRFPEGKIDDGHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZ37</accession>
    <name>A0A9P6MZ37_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Mitochondrial thiamine pyrophosphate carrier 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BGZ80_007452</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000382">
        <property type="protein sequence ID" value="KAG0018202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZ37"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24089">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RRM" evidence="12">
        <location>
            <begin position="23"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="13">
        <location>
            <begin position="102"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="13">
        <location>
            <begin position="129"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="299"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="398"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="525"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="142"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="597"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="167"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="237"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="279"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="607"/>
            <end position="632"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0018202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="16">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="632" mass="70196" checksum="9CB36BB4D1D19DE0" modified="2023-09-13" version="1">MSLPPPPPPLPAEGSAPPSSTHTTVYVGHLSTRTERRDVEELFEKYGRILSVELKHGGFAFVEYEDPRDADDAVSKLNGYELDGNKISVEWSRRSGGPGSGCFLCNQTGHWARECPEASEKGMDVKSGKCFKCGEPGHLARFCRGPDTRRHGPSYGDYRRGPPPPMRYGRGRSPVPYGRDPYDYGYRGRGYSRSPDRGYSGYRPRSPYHSGGYRGRSPSPYYRDSGRGRSPSPYGLQSNSHHSSSSVQQVLEPHGTPFGADSADSRTQSRDSSSTARHGSKDGGKEQKVTVARNTKSLDYIVRNMIAGGIAGTVAKTTIAPLDRVKILFQASNPQFEKYAGTWTGVFKATRDIQKSAGIRGLFQGNSATILRIFPYAAIKFMAYEQYRNLLMPSRRDETPYKKLVAGSMAGVTSVFFTYPLDLIRVRLAYETKATPYIGLVRKIYSEPAAGSHPAHMRWLPSTGIANFYRGFFCTVAGMIPYAGVSFFVHDVTQEFCREHLPWTLKPNQHRGLPDKNGDYSRPELRTAAELTCGGIAGALAQTSAYPLEVVRRKMQVAGALDPKAFVGMLGTAKELYVAKGIRGFFVGLSIGYLKEEVEEEDKRDYEEEEEDDEEEEEDDEEEDDEEGGRER</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZ69</accession>
    <name>A0A9P6MZ69_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">NodB homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_007833</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000409">
        <property type="protein sequence ID" value="KAG0017861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZ69"/>
    <dbReference type="OrthoDB" id="407355at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471">
        <property type="entry name" value="CHITIN DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471:SF9">
        <property type="entry name" value="CHITIN DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="15"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="domain" description="NodB homology" evidence="8">
        <location>
            <begin position="120"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="47"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="47"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0017861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="357" mass="38364" checksum="7389B76ABA8F1784" modified="2023-09-13" version="1">MTVSEKKPMQTKNKVLIAAVSLIVVAGIACGVYFGVHNKSVNNNVSNSTSNNSTSGSTSSLVSPTPTLAGATPTPTNVLPSGQNGTMINGTLFPYYTLTGEAPVPVGIPGTVYTTCKTPGTFSISFDDGPSDYTHELLDLLDKENLKVTFFVNGNNQGCIYDPKVQSVLKRAYQSGHQIASHTWSHPKLTTLTTQGITTEMTRLEQAFMDVLGVVPRYMRPPYGDGTFGPAAKDAVVQSTLKGLGYVITTWDMATTDADIDDNNTPHKLTDEALMKIEQGQVTSVVNAGAKGATHMELMHDTYMRTVRIMAPWSINYAKGLGYKIVPVATCLGDEDPRTWYQKIGPPSANPPTTCTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N087</accession>
    <name>A0A9P6N087_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_006585</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioesterase PaaI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000326">
        <property type="protein sequence ID" value="KAG0018890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N087"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047617">
        <property type="term" value="F:fatty acyl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03443">
        <property type="entry name" value="PaaI_thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039298">
        <property type="entry name" value="ACOT13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003736">
        <property type="entry name" value="PAAI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00369">
        <property type="entry name" value="unchar_dom_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21660:SF1">
        <property type="entry name" value="ACYL-COENZYME A THIOESTERASE 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21660">
        <property type="entry name" value="THIOESTERASE SUPERFAMILY MEMBER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioesterase" evidence="3">
        <location>
            <begin position="53"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0018890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="152" mass="15959" checksum="0F3E1BA1022D33CC" modified="2023-09-13" version="1">MATLKHVQRVWSHFLEKGGFDTHALSGLKVVAASKGNCLSELVVAPHHLNRVGGCHGGLLSHIVDTGGSLAIAADGMYATGISTDLNVSFVSGAQLGDKLSIKSRCLKLGGTLAYTDVEISVGDRIVAMGRHTKYVRVAHKANAEKKLDGQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0M4</accession>
    <name>A0A9P6N0M4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_003506</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000193">
        <property type="protein sequence ID" value="KAG0020836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0M4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21245">
        <property type="entry name" value="HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="41"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="173"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="24"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="128"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="182"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="198"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="219"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0020836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="233" mass="25070" checksum="8AA91E64B2AF2CC7" modified="2023-09-13" version="1">MASSTHTTSSASSNPLTYRKPQHESTPSHSSPSKAPALDEKRIYVGNIDPTLDEYAVLKLFTPFGKITKLDFMFHWHGPKKGTPRGYCFLEFESSSQAAAAVKQMNRKVIKMRPLSVSLANMAPPSTDGEKGRKRTLDPNRPTAFSLLKAGALKNASTDEKIKAMERKLAQMSEPAKPLPVPVHSSLPLKPTVTMSLSSHGGSNNINRGGGGGGRAHRGAGASSSSSNRNRPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N106</accession>
    <name>A0A9P6N106_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">1-phosphatidylinositol-3-phosphate 5-kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">FAB1_1</name>
        <name evidence="2" type="ORF">BGZ80_005137</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000255">
        <property type="protein sequence ID" value="KAG0019880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000285">
        <property type="term" value="F:1-phosphatidylinositol-3-phosphate 5-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45748">
        <property type="entry name" value="1-PHOSPHATIDYLINOSITOL 3-PHOSPHATE 5-KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45748:SF7">
        <property type="entry name" value="1-PHOSPHATIDYLINOSITOL 3-PHOSPHATE 5-KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="741"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="973"/>
            <end position="1063"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1154"/>
            <end position="1175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="82"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="741"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1004"/>
            <end position="1040"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1045"/>
            <end position="1061"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1154"/>
            <end position="1173"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0019880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1293" mass="143429" checksum="2E0358ABD0A45A20" modified="2023-09-13" version="1" fragment="single">MVSSKPLPPIPAPAVEKEKRAQLFPSMTNLRRKSEPPAADSNASPTQVQTEQLQTQANTQAQPIGTISSISGMISSFISSTALSTTKTPTTESNRPSRPSTPVPTAATVVAVPLETAMAEETTPTVPAKQEMVTLDQRSFQHLRAIARQSIASSCLEPEILWLKLFMDMVQKLAANASDTWLQVEAAYESALEEQLEGTATLVEKDKLNDKEKHKEGKDKPVFSYRVSLAKQISTKQECTFTVGRFEGESILQEERSITEQRKSAEDDGTKILLGGTVFLAAGSEDLPKAGKIVEILVFALCSLQLETYLMRDHDVLRPDPALNIHEADTKFSKPPVTTQYSHDTSKRASKGSMFFGWLSRGSLPAKYKKGTTQLALDSDTKLDQYRNNSGSGAVNAISSSSDDFGLVDDPQGFQNCRFAKIIQQVEKAIISVSPNVVFPPPHILLRLRDEEAFGLDSIRKPYNWEDVEFVARKIGFGNRMSRQNTAGVSQVARFGAITGHAQNDGSKANRLPADSRAGLDHLMTNSNSLQGIFNHQSISFSYSYYWSATAAAPCHPPNLITVEYYRKEGQYEDMGLGEMIEFICKRAYSKCSDPTCEHKRLEHISTYTHGEARINITVEQPRPDSATNFDSEEFTPFLSNNKTIAVWTRCKMCKARTKPKALSRASRLYSFGKYLELLLYGQRFEPGPRQLCDHMATKDSIARCFLYRGLVVTFEYESIDLFEMRISRLQVHEDFHPMPRFDPGHTDEDKHEYSTAYSTSTGPSPRASVLSVYLNSDYITEKEQMSLLDATRLEILHFYESCKKIIVIMEQHLGETKSISKYVINKARDSSNAVAMDPIKKAALSRLDELGERWKADEFDLYDQLKRISICRLNDLRNRFVDCIKRTMRSMEAWQKEYNPESLKSSKGQLDWVLPEYFTHDALHTFPGSSVIVREDEPSSIIASTLSRSMEFTQSSSDYLSLISSLLHPDSESTEVEGKAPLPPEKDFDINSLNIPTRGPLKTSRSAGSVTLTPRKSGSSGSEGSTAHGSPGKENSASQKGELETEDDIDEDEEEDEEDSFLVVDGYQTSVKFVPASKVDLSSLIQNGTMSPRSTIGLNFGGRHSKNSMLSPNTVDKKGDLVATRPFSMVALPNSTSALTTSLMPANGEETPTNPFFVSPPESRSITPTPGTKSKGAFGYHSLASGLSGTMKGLSLNTLSEKIGGGFSSYSTSGTYNEKAEREHFSDSVDKAMKETLAIVREKFSTTRSPHLKARFSHGKTSFSCVVYYAAEFDTLRRRCGIHQTYVPSLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1L7</accession>
    <name>A0A9P6N1L7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Amino acid permease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_002248</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000155">
        <property type="protein sequence ID" value="KAG0021509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1L7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050367">
        <property type="entry name" value="APC_superfamily"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42770">
        <property type="entry name" value="AMINO ACID TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42770:SF7">
        <property type="entry name" value="MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="125"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="164"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="213"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="259"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="289"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="323"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="349"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0021509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="611" mass="67219" checksum="C6C317ABEC848578" modified="2023-09-13" version="1">MSSGAYAFFLNISAKWVAGIMATLAILDYMATSVLSAASATSYLSSQFALPSAFGVFPLTIVVILVFGVITFLGVRESSAMASCIFVGHLITITVVMGAALVYWIRNGNDILISNWQTPHPDTNVASLIWNGFCLGLLGVTGFESAEGYLEDLKPDVFPSIIKYMWICITVVNAPITLLVMAVVPMSEVIDDPDSSILTLAKAASGNSPWLTYWLVIDAAIVLGAGVLTGMVGVLGLFERLSKDQILPPFLLIRNKWTGVFQYIILFFMVLCVTLYSTTGGDVTSLSGVFAVAFLCVMVSYALANIMLYTNRPRLSRGNATRVPIFVSTIVFGILVGALVGNIVIDPPIFKTFVIYFAIVHAVLLAFMNRVWILRRILKITGIGATAFVPSIRSTPVMDMGQTLYEENLSDSADMGPSVDVPIDIVRLKNVGSSSVPQRAAAPVGDQGLAVEAVEQEEATEGRNSPQLVTQGFHRLVKAFNSMLIKSMINSLRNHPVIYFTKNDSLTRLHRAIRYIRQNENSHKGNIRLVHIYQRVEHIPKRLEDNHRFLDELYPKIQIDLIFIQGTFDPDTIHAISQRLNVPKPAMFMSCPGEQFPYKIEEFGGARIIMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2B8</accession>
    <name>A0A9P6N2B8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glycosyltransferase family 49 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_002835</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000172">
        <property type="protein sequence ID" value="KAG0021219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N2B8"/>
    <dbReference type="OrthoDB" id="411524at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015020">
        <property type="term" value="F:glucuronosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042285">
        <property type="term" value="F:xylosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035269">
        <property type="term" value="P:protein O-linked glycosylation via mannose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051292">
        <property type="entry name" value="Xyl/GlcA_transferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12270:SF25">
        <property type="entry name" value="GLYCOSYLTRANSFERASE-LIKE PROTEIN LARGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12270">
        <property type="entry name" value="GLYCOSYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13896">
        <property type="entry name" value="Glyco_transf_49"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0021219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="382" mass="45013" checksum="52FC4B4F60015195" modified="2023-09-13" version="1">MFTSPPEPGQAAFDVESITYSNQVITWKTPNGRLKHEIDEDAVIHKVFSSTIQPSKVLPYYFKAIREFDPEAVTITTLITFDRYPVFSKLVTNYQGPISVTIHINDDEARDENLSKLHEMYGSNPYMKEFVDVHVVVDKFNRQFNMWRNVARFFARTNYFMMLDVDFHICTNLQKHLSLDPEARQLMRSGSAVLLPAFEYVNQDDGYDSSTFPKDKESLIQSVRSKKLTTFHDFFPKGHNATDYERWYKTDSVYKVTTYQHSYEPYVILKKEGTPWCDERFVGYGANKAACLFEIYISGIDYYVLPNDFLIHQSHPYKEETRKQERKYNRKLYQNFQEEACFRYSMQFVAANKWDSPKADNLREQCNKIKGFKQAMEHFSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3T5</accession>
    <name>A0A9P6N3T5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_011678</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000097">
        <property type="protein sequence ID" value="KAG0022602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3T5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33324">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33324:SF2">
        <property type="entry name" value="MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="139"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="260"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="154"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0022602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="368" mass="43495" checksum="94B01CD8ADAE6765" modified="2023-09-13" version="1">MEMLMDWATDPDNYEKYTNPNAQEAEDLFTEIAKKINAKYDTRWHKTVINHKINCARQSYDAARELIASAEAGKLDPKILQRRLMFVCPLYNKLHPFYTSMAAGSNSSEHQTDYSGSTLGKRVTSISDDLEEDIFGSDNSFYDLQDSEGEDEQSERGESARPGRSEALQRDEPGSSYTEKRHISQDDTRTLEVAGAVNEITTMYDGVNNQQYSGEYSHYRCDYRDYEDIHIRRIQELERSHMGMFEKRTQELEMTFNQRMKELAEERATFSARMDRERGEFLAMMERERKEFATKMDRERMEFTAKMEKEEADLKERRQEYKEERQDLKQQMHELKQQVLVIQSERLDLVRENAALKKELEIRLFRMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3Y2</accession>
    <name>A0A9P6N3Y2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribosomal protein S15</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RPS15_2</name>
        <name evidence="4" type="ORF">BGZ80_011177</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000087">
        <property type="protein sequence ID" value="KAG0022767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3Y2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000028">
        <property type="term" value="P:ribosomal small subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.860.10">
        <property type="entry name" value="30s Ribosomal Protein S19, Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002222">
        <property type="entry name" value="Ribosomal_uS19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023575">
        <property type="entry name" value="Ribosomal_uS19_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11880">
        <property type="entry name" value="RIBOSOMAL PROTEIN S19P FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11880:SF2">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00203">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002144">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54570">
        <property type="entry name" value="Ribosomal protein S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0022767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="87" mass="9985" checksum="BF828F5D900DF658" modified="2023-09-13" version="1" fragment="single">ADEHHDDAAVDVKKKRTFRKFSYRGIDLDKLLDLSSEQLMDLTFNQVEIKPEMIGHYLGEFSITYKPVKHGRPGIGATHSSRFIPLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4H1</accession>
    <name>A0A9P6N4H1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003098</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000018">
        <property type="protein sequence ID" value="KAG0024430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N4H1"/>
    <dbReference type="OrthoDB" id="2380010at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="23"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0024430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="182" mass="20776" checksum="37C9C4248AE7B396" modified="2023-09-13" version="1">MTETDIHYNRGYSKVPTSLYPLLDYVIPNAQDHQTLVFAMRKACGWDSGNVSKWFVQQAEGTRLMAIFYLPGTETPVGMGGVELMDFDHQDKDIADPETKRGCVVSLFLYKNFRGKGYLGKMLEICEEIGRKKGLETLTLYGLNKAGGYEKFGYKTFKIEKRNYGGNNNWETRFLQKSLIDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4P9</accession>
    <name>A0A9P6N4P9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_009196</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000053">
        <property type="protein sequence ID" value="KAG0023514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N4P9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040137831" evidence="2">
        <location>
            <begin position="29"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="68"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0023514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="139" mass="13288" checksum="3DAFE18788ED1874" modified="2023-09-13" version="1">MKFLSSSARFVLASVVLFMTMSATMVTAASNATDTTTSSGFSGPTTIPGPPSASVSVSVATSGTAASVATSGTTVPVPTSGTVVPAPSASSSSRGILPIPTTGSIAPNSTTSRSGANSGSKATVLTAVAGLVVVMAIGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N6C2</accession>
    <name>A0A9P6N6C2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001724</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000014">
        <property type="protein sequence ID" value="KAG0024532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N6C2"/>
    <dbReference type="OrthoDB" id="2383020at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="433"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="433"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="450"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="467"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0024532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="570" mass="63273" checksum="D35DD761690B585B" modified="2023-09-13" version="1">MDNLPVETFQVICSFCSLHVLANLRLVSKTFRDRVDGSLTARRSHATPRSAILPKGEHDQNACYIRVTLSRQHEPITVIYNRYNIRHNYLEFSQNSAPSVVDGLGIVPTRVPESATQNPYHDFSLGKLDLNLWEEQEKEAIASGSHPSPPPSTTETTEMDPSVNPGRRGRRSSITQASIIRRTEHQIGQEIASGGPITPLSQTRPVRNALASSFGTASPSGTLASSLPRDHAAQGDNYMVRFARMMLGSTGSGPQSAQTRPGMTAAELAEQARQLIHTVDPEVLSSKKQYKFILSPGVHFVGDNGFIMRYTISLDPTARLLFKVDYIRVSWRWVASGVPVVLEPRLKGGLYIADPMTRKDPFPSQRIGGIYAERYNLLLREIHNQEIDHRARGELALVGYDENVLPRDFISVNLLSQPVLAWITRIDNKRTWTKPPKERKETSDGDLSESQDASSSSQDGLQRDETESSDSSDSDWEDLTSPGGLKGPSTGDAEDQEALQELLRSIKYNAGYLTARNIVEEMLAEKGYSRDLIWKYGIVRREMMGPVPGVAHAKQLLQKILASEAAESNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N6G8</accession>
    <name>A0A9P6N6G8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_003716</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000020">
        <property type="protein sequence ID" value="KAG0024371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N6G8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051615">
        <property type="entry name" value="Transcr_Regulatory_Elem"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313:SF81">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="8">
        <location>
            <begin position="275"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="714"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="777"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="828"/>
            <end position="963"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="21"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="37"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="75"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="720"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="741"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="828"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="874"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="893"/>
            <end position="914"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="935"/>
            <end position="960"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0024371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="988" mass="109662" checksum="635AD38B5203A910" modified="2023-09-13" version="1">MADSNSTKHRRHSSKKTGTNSLDSHSSSSSRPYSTSNNPTIDPNSSNNMNKKRVSKDQSSSKLKQKKTDSRADSDPGSPSPLLSPQDSSNGSSSSTGATKSGEDFKSVVSTMSLDGHGQHFHGSSSGFYVCQLSSRYRQGVYPLPMAHLNDSDLWSHSLQMTSERELPSKVEMDTLLGLYFRYMYPFAPMFIRKSFMEQHAQNRPDLSQILILNAIFCNACWYSDDPLIRQDSTKYFNRAKIILDETYHVSRVSTVQALLLMSHHQYAVGNYSGGWLYTGMATRIAHDIGLHRQDVQVNEPEEAEIRRRVWWAVYIADRLGGGILGRPLNLRDKEYNVQMPSDDWISELGGDDAVEYPYEPERIISCRLLWSVKLFMQMGNVLNTMHCIEAEINGAFLADISRTQLPQLHNSLTSWFLSLPNELMYTPYTMSPNSNHPPSPPTALMHMFYYTTLTMLHRPYLRPVNSAAIDANFLVSSRNICTAAATNVCHIADSLMLHGQLRDTCYYGMACLLAAGTVHVHNAITPTPSNRETTRAGLSKTVKAAHELVKTFPVAESLIAVALDVFASQTSSVPTEMAASFIDISTFVAPFIDMTQLQATSIGNIYEAARLAKLAKDGPGPAPSIQLRHPYGNFSMPLPEGKDHSSTKLSSMWQSQIATAVAMAAIAFGGTDPQQEQQFFANPLELPEALRLAPIDSVMFQVDGTTGLETFGTDPLQLGNLQTGNTIGTDNASTSGFHMPQQPQAQQLQQFQQPQQQQQQQQQQQQQQQQQQQQQQQQQQQSNSSVPLTHAEPQFSSSSSTFDATQALNLMQAAIASSLQVGSSMQHLQQQQQHVQPSQRSQVVQAQQHAMMEDDTADPPSPPAISSDDMDTEASQSGDTPSPDSISAPRQDAQTQCDTSSDYSHESFMSSLTEDARHGGSLPFFIDNHDDALQQQHQQQQSKAQPQQQQQQQQQQQNHHQLKEGYTCHKDVEQVNTLLFDGHAMEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N6L5</accession>
    <name>A0A9P6N6L5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_010273</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000007">
        <property type="protein sequence ID" value="KAG0024694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N6L5"/>
    <dbReference type="OrthoDB" id="630895at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43328">
        <property type="entry name" value="ACETYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43328:SF1">
        <property type="entry name" value="N-ACETYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="46"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0024694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="237" mass="26966" checksum="C6F46669903FBC94" modified="2023-09-13" version="1">MSTQPSVQETTNTVAEPQKDVRSPEEIERLCKLHDSYKPIWLTETIQLAPVLPSDKEALIRHLNDPRINQYLYGPPNPYTPEDADQWIAGRIDRMTKNGTPLNLHLRDMAKGGIAIGAVTASDASDDDLQGDDTGYWLDPEYHGKGLMAKALRMILRRVSIDEVGKRKFNAHTFAENWPSRRTLEKAGFVFQPEMQKSHIVAGREIKIWVYRLYLTDEDISKMEIVEEAVPLPSLIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SS12</accession>
    <name>A0A9P6SS12_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007879</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004119">
        <property type="protein sequence ID" value="KAF9994238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SS12"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040113056" evidence="1">
        <location>
            <begin position="26"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9994238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="158" mass="17174" checksum="AE28232298E94286" modified="2023-09-13" version="1" fragment="single">MAFKRVSSALRLLCFVLALSGLCNSAPRSQFSMNAVEMQQYHPQDDTKDDGYHVNTHEVEITLTHPHSFMELYGWIPHMTDGISQIRMSTVEPCADFSIQIVEFHVCQYDRGLTMDVGAFGIRSSVIACADVNNGCTVTAINGIAGKVGATGLCIGGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SSW7</accession>
    <name>A0A9P6SSW7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_007037</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003532">
        <property type="protein sequence ID" value="KAF9997321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SSW7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050562">
        <property type="entry name" value="FAD_mOase_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356:SF2">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356">
        <property type="entry name" value="FAD-DEPENDENT MONOOXYGENASE ASQG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="11"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9997321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="325" mass="36260" checksum="9C0F2C447F82BFF5" modified="2023-09-13" version="1" fragment="single">MNPDALSPTNTPVLIVGAGIGGLTLGALLEKAGIEYRIFERAKAVKPLGSALSIGSNVMPVFEQLGILDQILKNAKPFPFSTGYNEQREATRILDYSPSEKIGGYLPHIVSRPILYDILAKLVPPHKIIMGKKILSFAQNHEGVMIRCSDNTSYHGDILVGADGAYSAVRQSLYKELNKKGELPKSDNMPLPFNSICLVGQTRPLDPELYPHLKDWHTWFETTIGEGKPYAWVTFTTKFNTICWMVLRHIDDKARELESSFRNSEWGPEAADSMCKEVRDFPIPRGTLTIGDLIDNTPKDMISKVMLEEKLFDTWYGGRTCLIGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ST88</accession>
    <name>A0A9P6ST88_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_006541</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003234">
        <property type="protein sequence ID" value="KAF9999580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ST88"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040290807" evidence="2">
        <location>
            <begin position="28"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="106"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9999580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="178" mass="19293" checksum="DD48CC41949B4DD6" modified="2023-09-13" version="1" fragment="single">MRVNTTRNWFVVPLLLGIPAVMALVYAAEFDAASSGLLDDDVQTRRHLYANRELHLSLVNEGSMAIEAHEESSKLTTPSTEHTSQVTFKPTTKAAHRPEPVKTPKAKPTTATTTTTTKQTETIPHTTAVTHSALTTTSHTTTTDDDIDTTTKTVPHITTDSDVDTTTKATPHTTTVSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SUT1</accession>
    <name>A0A9P6SUT1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_005491</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002701">
        <property type="protein sequence ID" value="KAG0005238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SUT1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035673">
        <property type="term" value="F:oligopeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004648">
        <property type="entry name" value="Oligpept_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22601">
        <property type="entry name" value="ISP4 LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="153"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="177"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="215"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="255"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="290"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="360"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0005238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="392" mass="44108" checksum="2B87BBB7B757BF8D" modified="2023-09-13" version="1" fragment="single">MSEQKHEYINEKDVIDEKYDLERSSVVLEEEENSPIPEVAAIVSNTDDPSLPSLTFRFWVMATAFSVIISFCNQFFWFRQNPITIGMSVVQLLAYPIGKFMAKVLPSGFLNPGPFNVKEHVLIALAANCASGTAYAMDIIVIQRVFYGQNFGFLANFLLILTTQMLGFGMAGVLRRYLVYPAAMVWPANLVQVALFGALHKDEDLSSGQWSRYKFFMVAFIAVFFYEWIPTFIFPVIGSIAWICWIKPSSTLVSQIGGTSGLGVGVISFDWSVVTAWLGSPLVVPWWAQVNIGIGFFLIAWVIVPIAYYTDLWNAKLFPILTPALFRVNGQSYHATEVLTKGQLNETLYEAYGPLRISTFFALTYGVGFAGLTSMLTHTWLYHRHKLVAQWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SV54</accession>
    <name>A0A9P6SV54_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Stress-responsive transcription factor hsf1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">HSF1_1</name>
        <name evidence="10" type="ORF">BGZ80_005184</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the HSF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002572">
        <property type="protein sequence ID" value="KAG0006676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SV54"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000027">
        <property type="entry name" value="Heat shock transcription factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF427">
        <property type="entry name" value="HEAT SHOCK FACTOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00056">
        <property type="entry name" value="HSFDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00434">
        <property type="entry name" value="HSF_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="9">
        <location>
            <begin position="135"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="17"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="292"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="373"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="578"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="20"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="44"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="294"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="373"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="587"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="620"/>
            <end position="643"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0006676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="664" mass="71592" checksum="AA202A655CE3390C" modified="2023-09-13" version="1">MALVNNPDTALALLQATSPNGVGSSNGGNSNSTKAQGPTDAMPNANNMLVSGRGTTNGSRSTANKGSKLSAASSSSTPAMPQPRPSSTARGNVAAFLTKLYNMVNDEASNNLIKWSDDGQSFLVLRHVDFAKEVLPKFFKHNNFSSFVRQLNMYGFHKVPHLQQGVLLPDSDSEQWEFSNPHFQKNQPDLLCLVSRKKASNGNEDKDPFTMDLGHILQEVTAIKKHQIAISSDLKSIERDHQSLWQESVAARERHQRQQETIDKILRFLASVFSGDKKRAIVPNKRPRLTITDGELDDDYENEVSQESAGEHEEEVTKLLGSKRKRASMVESEADYILPGMEARGSPKTKPTFNVDEMTPASLALLANANKSAQSNPASSFSNPTFTPTPIPTSTTATSSSGALPTVPDTASSLPDYLTSLPTTNYVNQSFKLDPSNLAIPTAFLPNNISPMHHDMLRSISMANAQETAPAPLPPSFAQTPAGANVVKGVDDIAKEMEQLQKSIEALEAHGLNVDDFNFDNNYLNSDAFDPSAYGDLTSINESGIPYQDTLENENEAMDDMIHTDQDDLDFITPELSHQHISSGQMTPVSSVNSPNVSSVQTPVSILPHSVCPVSPPNDTPADTASSPPTPASSVSAHSTSAANLRTSTVGGECLEDLLHTDAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SVU4</accession>
    <name>A0A9P6SVU4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chaperone DnaJ C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_004562</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002311">
        <property type="protein sequence ID" value="KAG0007531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SVU4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006413">
        <property type="term" value="P:translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10747">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.260.20:FF:000002">
        <property type="entry name" value="Dnaj homolog subfamily b member"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.260.20:FF:000013">
        <property type="entry name" value="DnaJ subfamily B member 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.260.20">
        <property type="entry name" value="Urease metallochaperone UreE, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051339">
        <property type="entry name" value="DnaJ_subfamily_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24078:SF553">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY B MEMBER 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24078">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="HSP40/DnaJ peptide-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chaperone DnaJ C-terminal" evidence="3">
        <location>
            <begin position="42"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0007531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="213" mass="23017" checksum="2A263D993FB19F6B" modified="2023-09-13" version="1">MGGMGGMGGMGGMGGMHGMGGRPRAQQQQQQSPEKPAPLVRTLAVSLEDLQKGVTKRLKVTRKVRDGSGRTADKILTIDVKPGWKAGTKIRFPDEGDEYPNGTTQDIEFVLEEKPHPVFTRRGNDLIVDLELTLLEALSGFSKTVKTLDGRILPVSASGSRVIQPGQEEKFPGEGMPISKKPGQKGDLIVRFVVKFPTQLTASQKEGLKKILA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWF8</accession>
    <name>A0A9P6SWF8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_004268</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002196">
        <property type="protein sequence ID" value="KAG0007752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWF8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0007752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="528" mass="60121" checksum="B05AA7D4190685FA" modified="2023-09-13" version="1">MTRIINHPQEFRVRGSSETMTMTDINHSQAFQLRGSFETTFIPSILDNTAGCQVIRWKDIQRVFKDIDCIMNEGNLVLFMTDDDLEDLIPLRIVHHPGITLEVVVGSPSVGAASVEPSDPPPMYSILHPILEKEKAPLDRPTVPQSDTSHVSATDIGLENQMGLQQTLRHLSIVHRRIRNILSNNRELYENPPPRLFFILPKASQARNNTGGPAPKQFQLYFLCDCGQHTSTYISKVRHEVHVAKHEGYDLERPKEFLERYGLYTMAMMQMIKYGFEEEGIVIPELTESDLTSNIEGAQRHINFATKSITSLIDETISYIQHLRDDIGGYSENDENKTELGTSREEESLDLQQIDSYLNIENEEQTLGNLSRIITQDRHVRWVCSDHSREIYRDSAVQELETFVDANQGTFIEEKGRVIMKIKSRAMAKEFYRIMSKNCGIQELETAFEFNASLKTLDVFSSVVTKANILSLSLNGQNINVGNTTCSRTFGPIMKIMCNKRIQSIQLQNFKDLHLHTNVPTVDVSDQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWI9</accession>
    <name>A0A9P6SWI9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF3752 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_003648</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001983">
        <property type="protein sequence ID" value="KAG0008253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWI9"/>
    <dbReference type="OrthoDB" id="73491at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022226">
        <property type="entry name" value="DUF3752"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046331">
        <property type="entry name" value="GPAM1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46370">
        <property type="entry name" value="GPALPP MOTIFS-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46370:SF1">
        <property type="entry name" value="GPALPP MOTIFS-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12572">
        <property type="entry name" value="DUF3752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3752" evidence="2">
        <location>
            <begin position="5"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0008253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="144" mass="17006" checksum="7C5FA5E6A46BD635" modified="2023-09-13" version="1">MREQKPQDSTLWTETPADREKRLRGEPKDADDEDPRRHKKSKRRGSDDDEFTQKSQADIEREEQIRKYNAEKRSESLFEAHATKYVKSKAWQQNAEDNPSARPFDREKDVLGGRRIDHRQRDELVKQAMDLGSKFSRGKKSSFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWS5</accession>
    <name>A0A9P6SWS5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_003692</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001999">
        <property type="protein sequence ID" value="KAG0008212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWS5"/>
    <dbReference type="OrthoDB" id="69177at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004656">
        <property type="term" value="F:procollagen-proline 4-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045054">
        <property type="entry name" value="P4HA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869:SF241">
        <property type="entry name" value="FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="6">
        <location>
            <begin position="130"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0008212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="241" mass="27108" checksum="562FBCFEB44A886A" modified="2023-09-13" version="1">MAYSQNQPQSPLHSILEPRLTARLVQSPAVPTHLDLKPLLSLHRQQEEIVAFTLQNILSPQECQSLIERSEATGYEIALINSPNGQGVHIPGYRDGHRCIIDDHAVSAELWKRIKHHVPAVYKSRPVIGLNERLRFLKYGPGDKFQPHMDGEYRRTDGSGHVTKITVQFYLNQDCQGGATSFLQQQSLWADENEATRKVVAVPPKTGQALVFQHNLVHEGSKVTEGVKYVIRSDILYGPHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWX6</accession>
    <name>A0A9P6SWX6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Saccharopine dehydrogenase-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_002722</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001686">
        <property type="protein sequence ID" value="KAG0009114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWX6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004753">
        <property type="term" value="F:saccharopine dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019878">
        <property type="term" value="P:lysine biosynthetic process via aminoadipic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051168">
        <property type="entry name" value="AASS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032095">
        <property type="entry name" value="Sacchrp_dh-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11133:SF22">
        <property type="entry name" value="ALPHA-AMINOADIPIC SEMIALDEHYDE SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11133">
        <property type="entry name" value="SACCHAROPINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16653">
        <property type="entry name" value="Sacchrp_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Saccharopine dehydrogenase-like C-terminal" evidence="3">
        <location>
            <begin position="2"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0009114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="72" mass="7523" checksum="BE484CBB5D9D33E1" modified="2023-09-13" version="1" fragment="single">QSRTSTILEYGNPEGASAMARLVGMPCGVATQLVLDGVINKPGILAPMSADLVYPLIKAIEAEGVVCHEEIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXC4</accession>
    <name>A0A9P6SXC4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Copper acquisition factor BIM1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_002259</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Endomembrane system</location>
            <topology evidence="7">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001552">
        <property type="protein sequence ID" value="KAG0009571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXC4"/>
    <dbReference type="OrthoDB" id="2146436at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd21176">
        <property type="entry name" value="LPMO_auxiliary-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046936">
        <property type="entry name" value="BIM1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046530">
        <property type="entry name" value="BIM1-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34992:SF11">
        <property type="entry name" value="COPPER ACQUISITION FACTOR BIM1-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34992">
        <property type="entry name" value="HYPHAL ANASTAMOSIS-7 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20238">
        <property type="entry name" value="BIM1-like_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040316177" description="Copper acquisition factor BIM1-like domain-containing protein" evidence="9">
        <location>
            <begin position="22"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="178"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="Copper acquisition factor BIM1-like" evidence="10">
        <location>
            <begin position="20"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF20238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0009571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="198" mass="20224" checksum="2A2A3E053647587A" modified="2023-09-13" version="1">MKITTFASSMLLLCSSASVMAHFMLVYPPSRGFDDDAEPNAPCGGFNTVQTNRSMFPLTDGFVDINSFHPSSTVTINVAIGSNPNTSDFTAAAASSIAINHPGHACLPFNLTSIPGAANNTNATIQLVYSGGDGSLYQCADVVLVTSAPGFDKTQCINDNGSNTTTSTSGANSRVSSVGVSGVMASVLGVVVATLAMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXK7</accession>
    <name>A0A9P6SXK7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">K Homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_001742</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001400">
        <property type="protein sequence ID" value="KAG0010158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00105">
        <property type="entry name" value="KH-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22453">
        <property type="entry name" value="KH-I_MUG60_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056553">
        <property type="entry name" value="KH_Mug60-KHD4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10627:SF76">
        <property type="entry name" value="KH DOMAIN-CONTAINING PROTEIN YLL032C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10627">
        <property type="entry name" value="SCP160"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24563">
        <property type="entry name" value="KH_Mug60-KHD4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="245"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="481"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="549"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="634"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="110"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="746"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="947"/>
            <end position="1144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1220"/>
            <end position="1242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1262"/>
            <end position="1283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1401"/>
            <end position="1454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="110"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="132"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="766"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="786"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="812"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="968"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1000"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1024"/>
            <end position="1035"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1084"/>
            <end position="1117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1118"/>
            <end position="1139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1262"/>
            <end position="1278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1401"/>
            <end position="1413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1440"/>
            <end position="1454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0010158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1454" mass="157815" checksum="83125052C5AEAC1C" modified="2023-09-13" version="1">MAENTILSLCIPCPTPAVQARPVDETMTNAFQSLCNEISHSHHCQVILDVSLNNAPAKKRLSIETHQSVYNVTISGAYQNVVSARGALMRSSPLKPKLSVKISKASISADSFPESTTSPVVGSNDTTSSSTDESVIENSNPDTQQPELTLTLNSSSEPSAPSTTVPFCYFPVLPEFKSQVDQISSSTKTTITLVSSQFHALPSVKSAAAAHARQEMVELLVSGSWEDAEAARLLLLVAIDALQPNVVQEKIQVELKFQNMVGGRKRQILQDLMAKTRTNIYMASPFVQTSSKNSSPLDSRYNDVYITGEPDKVQVAKDVISKAYTRVQAAASAYTRQVSIASRKLDWMLLNHRDRLRSIMNDNATFIAFPPLGATHPVIIVYGESRVNVERTIRTVMQLSSQFHSGSINILSPVRENLLAIPMNPSNVLSPVANISKLVSQASGAEVEFRNNGFLIFGNEIQTRIAVQFLTDVDFIKTHHYEVRFSVELANEHREFISGKKNGKINRIMKATGAKIKFDPCNEYNFYVDLSSTIAVKAVEALSLLQEELPAEISFYVPETYHKRIIGVGGKNIQRIMKKYGVYVKFSNSEEFANLGGYFDNLDNVVARTPSKNAMNLENLKHAVMELVNPKDKDFVHHSISIPKQYHLSLLSDHAAALSEIHDATNATVRFPEKETGSDVICISGPECYIQQAISMLLSLVDEQYVYPVPFSEAMDRVLAKPEFKSEVLDKIKNEWNVTLVLPHPRDITDTTTTENGSRAEANIESKSSAASSSVPKSQGAVNRLGSEDHNDGPKSEGAGELARSLSSLTDSGDDDDDSEEEDHVFVFKYSRNNEEHLQSAKELLVKYLVHNQIEVYDDEIRVQRPRSDSFAEAFPHFNCKILSSVTGGELPAPVPAFSNYSLFQNTGNAFESLNRIPSSGVSGPNSSTPGTGSMVAPDIRALFSHGPSQGLPLLTPSPPRWTDHSRQQTSLPGVSIGANSSTVTSGPSYSPIQALGAIQHNSHSPSSNRLTSLPNDPWASPGKQQQQQQQQQKQHIPSNPGYPGAIGQYRTPPPGINNVGGNGFYSPNQQMFSPEGPYGGTMGFQTPVSSSHLYSGNNSPVQGSSSNVANYTNILGSHSPRQQQQQQQQHHQPSPQRPLSGSFISRGDLQFIEDKMASSPSFGPGYGPALNSGITRSHQQIYQQQSPFGQSMQYPQQRQRHSSHNSVASHHTMFLGPIGGGLGSTGGSVNSDDISTEDESDDAFDDMRNRYRSYPYQHQGIQATNGNFSSQTPSPSVVANRRGSVPSMGSMYSNQQLCQSGSPNHSSSPLPNVVRLSNSSSDLYGRKSLVNAMARHSIGQQTDVNFGPNRSSGGGFGGGLTGANMPNLASGSVFGNERDLFSSGLGGIIGGGTISHSSSNSSFNTLNTHTNNQIHKTGGGNSPTAGLSPSALPFLADSPLDRTGQHLVGDWDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXN6</accession>
    <name>A0A9P6SXN6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001890</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001447">
        <property type="protein sequence ID" value="KAG0009971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXN6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="228"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="281"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="19"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="135"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="297"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="333"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="369"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="437"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="462"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="540"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="590"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="642"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="709"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0009971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="709" mass="78512" checksum="26BF449DB8579B7B" modified="2023-09-13" version="1" fragment="single">MNDPELSSSQYGDRRERVSSPLPSLSNSSSLNDIHHHHHQQQQQQGRSPAPPPVKTRFPLSIGDHLAKAARRLSLVTTSSKEKDNHYNPPPSPALLRSGAISPDLKKKRNSTLDDFYSNIPQSSADGKENRDKSNNNSGSSGSNIKNGNNNNNKGKEKKPLVKIDLFNLKSRNNTSQVNLVSPPIALERSLPEHPSPPPPPSKETFWRGVMRQSVVCTEDDYIVLSQQNQLKEKTQVPRDNSKPGTEHFALGHTEHERDDDIKNNTPIQQDLLQQQARVASPEPFMRPMSPTPPPTTTMQQFRQQQPVSKSTTAAKDIPSVRPPLQTDDRMASTMSEDLSRLSINSYQESTSSVSDESLQMEDMFDVYDSSQDGSHQGSLRNTTVEEGDTRQQQQRQRNFLYQQSENKPLSALERIQLQQKQRSQEQERLADLIIPPSSSSKNGGHSTNILPVRNFSRDILPISIPGPTPSSSSSSSGAASATAAATATATAEAPSQQPGAATAAAMDIENSESAMLDQLLSLVPGPNRPRLPSQIEWQKGFEEMRQKRKEAAALTSSLGRQNSNSSRHSQESSDSRSRRHSMPDMPRGQSREDQERQRGDNFKNPMLMSSSPLHLPAGGATDVGLPNNHKRRSGNDDREQPLQQQPFQRQPIAKFTAEPKQTRNNHVMAVAGRTSSLDRPLGRDVVSPVERMRGSDKDAVDIAFDEML</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYF6</accession>
    <name>A0A9P6SYF6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001258</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001284">
        <property type="protein sequence ID" value="KAG0010691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYF6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="325"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="218"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="330"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0010691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="445" mass="49323" checksum="51A4B12099312399" modified="2023-09-13" version="1">MDEPAYATPAQDLIALDTIQQQPQPMDLFIDEEVVAFESYYHSNLRLNEEFSSLAEPTSDLGRTESFQDDYDWSLALQTSILAQTSSPVDAIAEQPSSLPSLEPLDDNCLAFIQGIFCIDEFLRFPEPISFTVPKPKPKPTLEPMSVFQPCETFPSFPASLPSPFPSPSPSIAETRAAAAVNNAAPWSLSQGSKETAKFASPTLEQQQQQQPSPPSSPSFSFSSSSSTTNHHHHGHRGSRGHHPKGGAAAAGAMDAVVTCDTTPYKRNSISNEDKIELCRVHDIIPGFQMNLLGEIYHIGRTSVYGVIEMKETFYHLSSEHMANKRIRSQPRSSSPSPSPSSSLVLSLPSPQGLSPSPFRRKDGRQMVSSIVSELRGQQQETELSMAEFESFQADFKQTLLYIANDMKQYRQEQQQALESNKRRKLRPAGCIIRNFAEKWVAKNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYK7</accession>
    <name>A0A9P6SYK7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Telomere binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">TEL2</name>
        <name evidence="4" type="ORF">BGZ80_001044</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TEL2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001230">
        <property type="protein sequence ID" value="KAG0010978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYK7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051879">
        <property type="term" value="F:Hsp90 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042162">
        <property type="term" value="F:telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051083">
        <property type="term" value="P:'de novo' cotranslational protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.720">
        <property type="entry name" value="Telomere length regulation protein 2, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038528">
        <property type="entry name" value="TEL2_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051970">
        <property type="entry name" value="TEL2_Regulation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019337">
        <property type="entry name" value="Telomere_length_regulation_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15830">
        <property type="entry name" value="TELOMERE LENGTH REGULATION PROTEIN TEL2 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15830:SF10">
        <property type="entry name" value="TELOMERE LENGTH REGULATION PROTEIN TEL2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10193">
        <property type="entry name" value="Telomere_reg-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Telomere length regulation protein conserved" evidence="3">
        <location>
            <begin position="678"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="588"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="795"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="602"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="620"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="644"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="797"/>
            <end position="808"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0010978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1106" mass="121466" checksum="5A2D15002859ECD9" modified="2023-09-13" version="1">MADSQDSEAISAYLTDLQNQVRASPSPTLSSAIRALSEPLSFLGLINANNGLTTTSTATTTTTPLWAGPIEPTFQKRQYFIQHLLPNHLDFILDNITLDWFYALPSAQQTSLFDVYFIPCLSLRQQQQQQQRQRQATATTQFQWEALMAVVSVQTLVSRINARFHENHSFLNETILRLLRKVLESYSLMDFYQGCYSVGQASGTAAAISSGGAKTTATAAEAVLISMWDSFLSKLFSIPTRVSNTLGGSGVVPSSSRVEIEDCFRDVIFFKRQATQLQSCLSSLAKDAVAEQNEKSKSSLKGQHARAYGVVITKFLRLGYAKILVESMVSQIWDKDMDSKCLGWKLALTHTASPATVSQFLVALVEHFNRNQLDFESSQRRQSLLPKNSAPTADQQQQLEIVHRAAKILVAIGFGTSDEKMDSNKNNNNAMVEQILFQGRVYGIGVLRMLICVQSGWPTGVQSGKDSILAKTFKKALEIWSDSMLVNHASADYQKYMSYQVLLMIGYFSQKDIFEADLISIFSNGMSNWLELESFQRKQIGLVVAEEFSKAVDTIGSPADFDLDGTDMEIRFARSLVHLKDGAKPYNPAVLPSIDDSKGPQECDEESQDEFADSRAANQEDSDDEEDPDEIVDQFSRANVRDDSDSDDDDDLKPYEMEYESDPDEDIGSSRKPKVAAPLYLRDLISYLRAGEDRDKTEMGLQHAAELIRRKAGSLELEEFAETLANTLVQIQDSFDLTNFYKMRENALVALVVTSPIIVSGVLTFQFYEKKNSVGQRLNILTALALGAQEISGFDRPPSAATSSSSAPIRPGQPSRSTLTAANSVYSTSSNTTGTATSSTSTLVGAGAQNQMSSRTAPVTFDSIASNISLARTRRFSQKSNIEASRPAPKANAFSNLAPVFLGGLLGRWGGNRGAGMERGYDVLQKAPAMVLKKFVVTLGVLVHYAVPITRELFRFLLALRYHTPPSQPTPGGAAPTSSMTGSAFSIPSLTSLKLPGEIGISSKMSSTSAAGSSSLLTLSSSSALPYNPDLLESILFDLLILVTPSSATLSDELLLHEFYAEVMECQQWAMELWEVYKLEEGSGDKARMYCAALLQRCFELMEVSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYS8</accession>
    <name>A0A9P6SYS8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Peptide hydrolase</fullName>
            <ecNumber evidence="9">3.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">LAP1_1</name>
        <name evidence="11" type="ORF">BGZ80_000758</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the peptidase M28 family. M28E subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="9"/>
    <dbReference type="EMBL" id="JAAAID010001165">
        <property type="protein sequence ID" value="KAG0011341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYS8"/>
    <dbReference type="OrthoDB" id="2214at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03879">
        <property type="entry name" value="M28_AAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.10:FF:000042">
        <property type="entry name" value="Peptide hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147:SF56">
        <property type="entry name" value="AMINOPEPTIDASE YDR415C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="METALLOPEPTIDASE M28 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 11" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 9" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0732">Signal</keyword>
    <keyword evidence="7 9" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040544724" description="Peptide hydrolase" evidence="9">
        <location>
            <begin position="18"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="10">
        <location>
            <begin position="171"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00043962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0011341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="386" mass="43801" checksum="FD15DC80FB7A61FE" modified="2023-09-13" version="1">MKFQSLFLISLASVALAAPSWWEQWTINKHESVISNDDQRLVQTAADKAPFWTSEKERLAMLRNNIHYMDITDNQDLGTHRVQSLGKKPLPLSAVHQKKVARYIDQLSTANMEVALTEFTKFNTRYYKSDTGHQSAKWLYKQISDLIEESDADSDVSIRQFEHKGWRQFSIIARFEGRNESLSNEPVIIGAHQDSVNMWLPILRSPGADDDGSGTVTILEVFRALVGTGFRPHRPVEFHWYSAEEAGLLGSQDVAKSYEKKNVDVLAMIQNDMTGYVGTKFAESYGIVVDYVDDELTELVRIYAREYGDIPIRETKCGYACSDHASWAKAGYRSAFAIEGDFSDSSPYIHTANDDVSHINFDHMKQFAKLSLGFAVELGYYKGEQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZR6</accession>
    <name>A0A9P6SZR6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA 3'-5' helicase</fullName>
            <ecNumber evidence="5">5.6.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">RECQL5</name>
        <name evidence="9" type="ORF">BGZ80_010812</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.</text>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family. RecQ subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.4" evidence="5"/>
    <dbReference type="EMBL" id="JAAAID010000795">
        <property type="protein sequence ID" value="KAG0013842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZR6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009378">
        <property type="term" value="F:four-way junction helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17920">
        <property type="entry name" value="DEXHc_RecQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18794">
        <property type="entry name" value="SF2_C_RecQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021369">
        <property type="entry name" value="DUF2985"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032284">
        <property type="entry name" value="RecQ_Zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710:SF152">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE Q5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710">
        <property type="entry name" value="DNA HELICASE RECQ FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11204">
        <property type="entry name" value="DUF2985"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16124">
        <property type="entry name" value="RecQ_Zn_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0347">Helicase</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="39"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="195"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="472"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="713"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1108"/>
            <end position="1141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="713"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="723"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="744"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00034617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00034808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0013842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1224" mass="136370" checksum="BD5F8ECDD788239E" modified="2023-09-13" version="1" fragment="single">MNNPKIQTRLSFKNHSGNTDDFQKEQQQRHASKAILDCHKCLRSGRDALVIMPTGGGKSLCYQLTAVMSKGVTVVVSPLLALIHDQATAMLRLGIKAAALNSSIGKKERADIIADLNISVPSLKILYVTPELLATGDFRKLLAALESRDMLARLVIDEVRFNSDDKYENFLGFLRGVYKSRKKRLQVESDKSTAPISSSVQEIEPVCGIIYCGQRLMCEELANRLVDDGIMAAAFHSGMTPKQRASVQQRWCSEAGSAVVAKNDSKEKPIDIIVATIAFGMGIDKPNVRFVCHWELPKTIEGYYQESGRAGRDGDISRCILYYSREDRTKIEFLLEVEKERRRVKSKQSSIQISNQQRTPAMDPAQTFQKMVAYCENVSQCRHVFLCEYFGETGVKKDVVCKDGVRCDICRTPEKVAKEKADKLSDIHRIGHLAQHMGGSKTVIGSDGHVQVQGSWRSASVALGRYDADLIGDEDGDAKDSDTSGSDSEDSGEISPTLEENEDEDPEAVRKAKRRKLLFGNSVEPSYYKKPAAPSKTSIEHIQAIAANRYGLFHIESPKVELKFRELCYETVERSLTSLLQGAHKSLTAEYFSRLGTEQGQLSKSEVDSRLARFAKTLAQEIEKKGFESSGTANTYKTVLGHRVRDIKGFETQARLGLATLSTATAMPQPAETSTTSKEQLSATSVPAKFQNQAWATAVQIIKHIMVNSKSSTSEESATYTAVHKDDGQEERPDQRQPNLVCPYTNSKNSNKNITCKTEPELQQPNNMTSAASKSKDRPTQTESFSLRTWIRNAPWIWGAFLVLLMGNMVKLADDSTQKLWIEIASQVLNGFFTLANVPVHPKRFLGYILGLRIWREDNAVRQQFVSRFLEDHMERRAAEGLTKKEYTQELLSMLDFYRCFPEYGHSRKAEEFNVGGTQDRSHPFNPREHLVPTTTSAVASAPKMSSLDCNAAQDQLAASNNFESATLLETSDSVAPTPSEGSVEVDIAEKDLHGLLAEEADRVVQSVVLPFLPFPMDTDSAAFPRDWQPSLDIEAPLEEMELSERSFMPQRTSMPLHSRRTLNRGSSYASFSKMPTKRTMPRTRARTMSMSIAKEAGSPTFVIHEGHHMRSGSPGGDPRGNVSSVMKEEEGPSSKKSKSLPPLIPMPLALTVEQMDWVDGRQVRLLKLQSDLQKGWPWYHYTIPDGIEPVDFFATRSEVELACSVPEESRETIMFSSSPSDLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZU0</accession>
    <name>A0A9P6SZU0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Dynamin-binding protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Scaffold protein Tuba</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BGZ80_011158</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell junction</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus</location>
            <location evidence="2">Golgi stack</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000864">
        <property type="protein sequence ID" value="KAG0013313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZU0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005795">
        <property type="term" value="C:Golgi stack"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031991">
        <property type="term" value="P:regulation of actomyosin contractile ring contraction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032955">
        <property type="term" value="P:regulation of division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00160">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00174">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004148">
        <property type="entry name" value="BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000219">
        <property type="entry name" value="DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051492">
        <property type="entry name" value="Dynamin-Rho_GEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001331">
        <property type="entry name" value="GDS_CDC24_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22834">
        <property type="entry name" value="NUCLEAR FUSION PROTEIN FUS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22834:SF20">
        <property type="entry name" value="SH3 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03114">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00621">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00721">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00325">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51021">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00741">
        <property type="entry name" value="DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50010">
        <property type="entry name" value="DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0965">Cell junction</keyword>
    <keyword evidence="5" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="DH" evidence="11">
        <location>
            <begin position="381"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="domain" description="BAR" evidence="12">
        <location>
            <begin position="603"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="10">
        <location>
            <begin position="1021"/>
            <end position="1080"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="191"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="328"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="868"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="25"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="91"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="106"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="208"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="270"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="900"/>
            <end position="912"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0013313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1080" mass="119335" checksum="79EAC82019591186" modified="2023-09-13" version="1">MLPANTIRTKNGGMEKKPPPPIKPKPTSLTTAPTDTSITSPPPTAASSAFPRTSIAVTDNGEPASTSFGDLRKAFERNQNASPLFPAGVGNLSSSGATGSSPNRASYSRVQQQQRLQSSSTLNVPTLNNGPSGNRPRSVSTPAPPARDTDGNVADSTLAPAAEPPVSKEGIDDIQPDFGNLRARFQSQANISVTIPDTPRPKPPKPVVNPSLKPAISAISPPAPMKPFRTLPPAIRTAAVKSPTPPRTPPRVESPEVERNPFGSDDDEPTSSSTSYSSSSNNAQTQLPARAPSKIHQNPIFQQLNNTLSNGGVRPTLATIQGRDSMMMGKAAPPAPQRAAPRPVSPTHGLPPRLPSRSGSVILTHTEESPEEKERKHRLDKRRRVIQELLETEISYSKDMLLLQEVYVTDMAESNLFSQADEKVIFMNLGEVVELTLDFIALLTPACGGGPDEVYNDSTTFVGEAFLQMEASAQHLLELDSRKELKPFFEACTEKCKGRTTTWDLASMIIKPVQRVLKYPLLINQIHVLTPPEHADSENIAKVQKEMVQIAEEINEIKKRKDIVEKIVGPKKKNDSDLIYHDFFILSASHGFSKKFSRTTQQIRQAVGGSDVTVDILFEALLEKFNMQQHLAREFANFILAWLVSIKQYFDTQESFAMTLREIYIMVPIHRNSEDHAIILVTEFHKKLSQFSKTIGRELEIQLKKTVYKSIEKFLKLFSGPLQVMKKREKKLLDYDSVRRMKEREETIDKNMLESAAAYTAINEQLLDELPKFLGLTTQYFDLIVMEFSKVQMFFYGQVKAKISEYFIEFFDPRASKDITGYVADMDLCEDYIAEMVRDDGPLARLENISLISNVGATHAAAFDEIRMTNQRRRRVNAPTLPPRSHSRSESNSSLPNPAQARTSWDSKTVPQGGTLDGSFDSMGMGSIQSPIQPRYYGEDENPFEIPESVFQDGSVVSDDYEPFGNNYAAGSVFGNRPLSIASSSYSFGSGGGGSDYHDFSHIKPPAMDDGMDADEIGLAQALFECTAIYPYSSTEDRQLSFEAGESIVVFGLNDDGWYFGKKVGKDVVGWFPASHCIQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZU7</accession>
    <name>A0A9P6SZU7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_010685</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000770">
        <property type="protein sequence ID" value="KAG0014060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZU7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0014060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="194" mass="21413" checksum="7FFF205F8AFEAF5D" modified="2023-09-13" version="1">MEFTAEDYPSVSSGDSADHIDIKLQISRIIREVLEVNVSRSTPEEGSNGKLVSVRRDVADALATVQSPASVVGVSTLILNEYKTCMSLQYAHIANHYVSSATDRSSDADLDNGAFNDASHKTQGLSPEQFFTKMLRGVDIPTLPYGLSDIHDDSVEVMKARLVLPQNLNDRLRGHTQRMGNKMEEEIDFDDPKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZX5</accession>
    <name>A0A9P6SZX5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_011011</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000832">
        <property type="protein sequence ID" value="KAG0013543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZX5"/>
    <dbReference type="OrthoDB" id="165058at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="178"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0013543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="206" mass="21982" checksum="27FE52E6743A5165" modified="2023-09-13" version="1">MPEYSRLNHSRGSLFVLSTKHTGTLAAVAVGLAAAARPLGTKLSDGGLLLSLGALQCGWIGATMAISFLEAPVKFLAPSPARRNLIDVGRHVFSAINKVEVFFSAFEILGWSLVAQRGLVGGPTAKGFRGFLGWTQFLRLTPALVVLLFESFTFLPVMRDIATRYVEGRPVDSAKIHGIYVVLEGIKVATLVASTASIGKALLQML</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0A5</accession>
    <name>A0A9P6T0A5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Chitin synthase activator</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_009677</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000600">
        <property type="protein sequence ID" value="KAG0015733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0A5"/>
    <dbReference type="OrthoDB" id="272077at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0015733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="677" mass="75120" checksum="A9DF4335EE96CDDE" modified="2023-09-13" version="1">MSATHILHRGRSVFSKLNKKYRLPASAALMTTSSNSSICSLSSSPCSPSGDPYLSTESCLSTDSLTHSQPSTPQELQDPSRARHLFDLAQQLLFGRNGHLKDESAAVEYYRLASQLGHLEAQGVLAFCYEFGLGVQADYLEAERLYILAAEKGNGLSLSRLAFLRKYGRPSVKIDRIESEYWQQKINQQGPSALAWLMEAAAVDNHDCCQFALGVCYHDGVGVEKNAIEAFHWYRKSAEQGNARGQGILGYCYGEGFGVERDRQKAMYWYRIAAEQGESVALYNIGYCYEDGLGVERNPYEAVRWYRLSAELGNAFAQNSLGYCYEDGVGIEQNLELAAMWYTKSAEQGYPWAECNLGYCNQNGIGVPKDDAKGAYWYRKAALQGHARAQHNLGFCYQNGIGVPKDPVEAVKWYMKSAERGNIFAFHSLGYCYQNGIGVQQNLDEAVYWYYLSAEENHAPAQLSLGYCFRNGVGVPKEPKEAVKWFYRSAIQGNALAQNSLGFCYEEGLGVEKNREKAVFWYEKSAAQNNPWAQCNLGFCYANEIGVKQDYEMAVKYYSLAAAQNHARAQDKLGVCLQLGQGIAQDVKLAVRYFRLAAEQGHIAGQYHLANALEKGLGCEVDLEEASAWFERAAANGCRTSHERLQRLLARSCLESGLTISESGLFLGAIGHCAPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0G8</accession>
    <name>A0A9P6T0G8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mitochondrial genome maintenance protein MGM101</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_009826</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion matrix</location>
            <location evidence="1">Mitochondrion nucleoid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MGM101 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000622">
        <property type="protein sequence ID" value="KAG0015506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0G8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000262">
        <property type="term" value="C:mitochondrial chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036297">
        <property type="term" value="P:interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000725">
        <property type="term" value="P:recombinational repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009446">
        <property type="entry name" value="Mgm101"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31404">
        <property type="entry name" value="MITOCHONDRIAL GENOME MAINTENANCE PROTEIN MGM101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31404:SF0">
        <property type="entry name" value="MITOCHONDRIAL GENOME MAINTENANCE PROTEIN MGM101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06420">
        <property type="entry name" value="Mgm101p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1135">Mitochondrion nucleoid</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="36"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="36"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="61"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0015506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="275" mass="30034" checksum="15C7CC03D73B7F42" modified="2023-09-13" version="1" fragment="single">MRAFATKTYVVKANATSAAKPVTTYASKSSVSKATSVKTTAAAKSEPLLTDPVTPSFSPKSYSTSPVSAASSSLPESLSYSDYSNDSSPISTSDSAPKITTEAGRVTEAFSSSNSILRDSAIGERTPDDGEDWTRSFSGMAIEPFEKEVAEILMKPLDPDDIEIKPGWGLAPRSDHSVSPKTISREYALVCRGRFVSTARGEQDYFDPSSLATASEGCKSNALMRCCKDLGIASELWDPSFIRKFKKQYCEELFAEHVVTKRKKKLWKRKDQPDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0L2</accession>
    <name>A0A9P6T0L2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">malate dehydrogenase</fullName>
            <ecNumber evidence="3">1.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">MDH1</name>
        <name evidence="9" type="ORF">BGZ80_009296</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(S)-malate + NAD(+) = oxaloacetate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21432"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.37"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the LDH/MDH superfamily. MDH type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.37" evidence="3"/>
    <dbReference type="EMBL" id="JAAAID010000541">
        <property type="protein sequence ID" value="KAG0016341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0L2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030060">
        <property type="term" value="F:L-malate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006108">
        <property type="term" value="P:malate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.110.10:FF:000001">
        <property type="entry name" value="Malate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.110.10">
        <property type="entry name" value="Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022383">
        <property type="entry name" value="Lactate/malate_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015955">
        <property type="entry name" value="Lactate_DH/Glyco_Ohase_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001252">
        <property type="entry name" value="Malate_DH_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11540">
        <property type="entry name" value="MALATE AND LACTATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11540:SF16">
        <property type="entry name" value="MALATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02866">
        <property type="entry name" value="Ldh_1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56327">
        <property type="entry name" value="LDH C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00068">
        <property type="entry name" value="MDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Lactate/malate dehydrogenase C-terminal" evidence="8">
        <location>
            <begin position="5"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0016341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="166" mass="17437" checksum="7D89771056E37D4D" modified="2023-09-13" version="1" fragment="single">LFGVTTLDVVRASRFVSEVKKVPTEKANITVIGGHSGVTIVPLLSQSGYSFTEDEVKALTHRIQFGGDEVVKAKNGTGSATLSMAFAGARFTNSLLEATVGGKKGVVEPTFEGVEFFATNVELGAEGVEKIHPVGNVNQYEQGLIDAAIPELKGNIAKGKKFINGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0W5</accession>
    <name>A0A9P6T0W5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_009718</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000607">
        <property type="protein sequence ID" value="KAG0015657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0W5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0015657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="204" mass="22708" checksum="EAFCB7AAF0D3FB88" modified="2023-09-13" version="1">MRFSSPNNASQLDLDSDLSQLFKGHGAQLESLDCREVLLGEWEMNALDEATQNGSSLKELYCTGLASDTSDEAIKSLAKIIARSELHLLHITLLKDDVCACILQSIQWEHLRELETVEGEEGLKAFFEEVSEKVELGYLKHRKIPTEPVIKDTPETNPAIGTRTIEIVERRNGEGVACLDTCYVISFTPGQPRPTVEETSIYLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T147</accession>
    <name>A0A9P6T147_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Coth protein-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_009385</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000558">
        <property type="protein sequence ID" value="KAG0016163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T147"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014867">
        <property type="entry name" value="Spore_coat_CotH_CotH2/3/7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40050">
        <property type="entry name" value="INNER SPORE COAT PROTEIN H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40050:SF1">
        <property type="entry name" value="INNER SPORE COAT PROTEIN H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08757">
        <property type="entry name" value="CotH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040334613" description="Coth protein-domain-containing protein" evidence="2">
        <location>
            <begin position="17"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="531"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="532"/>
            <end position="558"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0016163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="585" mass="64176" checksum="3CB43D932097D362" modified="2023-09-13" version="1">MRQSLVFLALTAIAQAAQVTFHVIAPGAKTVQVSVNGQLTALTASNPSIPLFSGAAETGSDTKYKYVADSVTETFDRQLPSGTETYNEFLGRPVTYADIPELPWPITNNPQWTRSGAKQSIFDTNYIPTVFVSGDATSLNSLIATPTSTKYPVTITYVLANEVQTFYNVSFGIHGAGKKNNNAKQSWAWQHPSNETFQLRTYFKIRHQEEDPTQIREKLYADISRAMGTYANEANMVRLFINNDGFGTFNMLDDVVEYSYPSAMFYAGNPPAQMGALFDGASGASFQYDPTGNGYYSWVQNAASPEDPSAVGPLCQLWNQTDKTNDAALAEVNKIFDLDYFLRFMVLEYLTGNWDAYWEEQTNDGLYRDPTQGNKWYYLAQDFDATFGVNIPTADPTFVGWSYKTFPTQFPGGVMINGLLENPTYQKTFETYLKNTVQVLFNNVTLTNRILKYHDFILPDLAWDRNITQRSPGINYGWTFAQTTENLWQGVAAPNANGGGATIGLIEWIVKKSSAVATEFSITITSTPVYPPTNGTQSTGGNSSSPSTGSSSSSSSSSTSAAGHAFPQALVTIGLIVTSMVALLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1D8</accession>
    <name>A0A9P6T1D8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_007791</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000405">
        <property type="protein sequence ID" value="KAG0017903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1D8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="63"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="357"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="425"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="142"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="63"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="82"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="100"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="358"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0017903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="607" mass="68363" checksum="F5357D60F24F4627" modified="2023-09-13" version="1">METHHVSNPWQQQQRQYNQDIFIPDPPVTFPLTDAETRSYDDFFHDHKKIFYQSKILLQRLQEQEQRQQQQRQQQMSHNDQLEDQTEGDEDGETDSQGTSWSGLGMNSPSNQSSSTLVDSVTILHMSDSGIDLEGDGLESLVQTLQSEVEDTQATVHDLEDRLNFAEITLRNAGKGNSLSASGGKYSSGYEDANIVYNRICIALQALIDEAQLSLQKNSTKHPSSAPEVNIQLKPNETIVTPKSEFVREQSPNNLEFEDSFSHCRSNKNPRITLDSVRMHDDAQTYELSPYSPASFYSATDEVSRIHWRQKHEEQHDRYRRSCQRVTLELEGRFQGLSTDSDDSEASFNLSRHKISRSLSVQLSPPSTSTTPSMPSTPITPTTPTLPLQGILRSSKKDGSRKERLKKKYQVQFLNPVVEGTSQQSVGLSTTKYRHEHQQQQPQYTSRSVGSTRSRGVLLQLYELWQQTWLRTRIMHVITGSVEIVIIIWVVIKASRLTLTWFGVQPSSVTQWITFIYGHRDGAGAGAKELYAKIRKDGLQMRQIKAWTQKEPVGLVEDLVAGAAASTGLISPSNIIYGPAKRVMAHAATGIALAFFSGGAKRLVRKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1J7</accession>
    <name>A0A9P6T1J7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_007177</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000363">
        <property type="protein sequence ID" value="KAG0018429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1J7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0018429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="144" mass="15906" checksum="6FBEEEDE23CFBE21" modified="2023-09-13" version="1" fragment="single">MNKSKLLTLVVKRKADLMEKNKSKELEGKITDIIEYLLCRLIISPEMRSGDSFSEAEVVVTEESSVNDGNLSRAGPMDAFLHAVKQPRVFGPTAFDDLLVRFVVTTKQSFSIVGNPAFKDLLNHATMAEMSQAKLPSDDAMATK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T217</accession>
    <name>A0A9P6T217_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Penicillin-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_005700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000280">
        <property type="protein sequence ID" value="KAG0019522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T217"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.600">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050491">
        <property type="entry name" value="AmpC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021860">
        <property type="entry name" value="Peptidase_S12_Pab87-rel_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46825:SF15">
        <property type="entry name" value="BETA-LACTAMASE-RELATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46825">
        <property type="entry name" value="D-ALANYL-D-ALANINE-CARBOXYPEPTIDASE/ENDOPEPTIDASE AMPH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11954">
        <property type="entry name" value="DUF3471"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase-related" evidence="2">
        <location>
            <begin position="1"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S12 Pab87-related C-terminal" evidence="3">
        <location>
            <begin position="367"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF11954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0019522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="465" mass="51994" checksum="67B03339761B7413" modified="2023-09-13" version="1">MSVAILHKGKLIFAEGFGKRNDRDPFTPETLTMIGSLTKAFTAATVGELVAEGKVDWDTTPVNKYLPEFELQDPGFTAKLTLADLLSHRTGFPPLDFAWFYNTESPDVLIKRMKYVDIDSKMSPYTQYNNVMFAIAGYAAANAVGVKYQDLVRDKIFKPLGLENTGFSSKEMSKHSNYALPYTATSYENAVDGKHERLHLTNLATAVAPSGDMYSNVLDLIRWGQTIMHYGKKDGKQVLNKDSITEILSAQSIYEKRSRSPDFGPLTAYGLGWTMNSYKGNNVYCHDGSTDGYNSNLALFPDEELVIAQLTNAYTDFTPGTLSYSIADEILGLPKTEDWMQKAINMTQAMYKKMGMANKELSPPRVMDKPASHKLSEFAGVYTNPIYGNLSIVLKKDGKGEDELNLEFRVYEGKLTHYHYDSFSTTFCHSAISVTDLVTFRTGQDGKVSGVQIRLDSWAEFEKQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T221</accession>
    <name>A0A9P6T221_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_006602</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010000327">
        <property type="protein sequence ID" value="KAG0018875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T221"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043409">
        <property type="term" value="P:negative regulation of MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14498">
        <property type="entry name" value="DSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10159">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10159:SF530">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE DDB_G0271350-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="6">
        <location>
            <begin position="352"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="7">
        <location>
            <begin position="418"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="151"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="261"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="62"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="154"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="180"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="268"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="294"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0018875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="507" mass="53525" checksum="B5698E6F056088ED" modified="2023-09-13" version="1">MDTPTHSLPLPQLQQNGKKLSSLDSLPSSNPKCSSSHSHSYPHLSHHSHNSNAKNCLDVGPSHQNTSAQGNTHNHNYTNRMRRSFSNARPLGSGLSLREQQQIRNQQAFMNSINNNTDSSLSLSITPPKFMTTYLPVDSQDQARLCNTNGYSTQQQGLQNGGNNSLSGGSNGSSGSSLSFPSTNTPRRASFSLSTGSLNFNPSNSSSMASPSSPSYSTIAVARARAAAAAAAAEAGEGGGQGVDAVGDELGIIGSGAFPGASGVIGGQQDPFSSPPSSSKSQDLSFNSRQSHPPLSESLTSSSESSLLSDASVSSTGSSSGSGPPSSSSSSTSASVVATQSHLQNNADAEREISMILDNFLYLGGDLVEEEQILELERLGIKRVLNMAINCDDLLWIERAGKDNGSYLKVGLLDHVDQDLKAGLDKAIKFIASSTTPVYVHCQAGKSRSVATVIGYLIQEHKWPFKKAYDHVVERRRIMSPNIGFVSQLVMLEERVLGPNKAGGLAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-06-18" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2D6</accession>
    <name>A0A9P6T2D6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">Potassium channel</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BGZ80_005158</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>K(+)(in) = K(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:29463"/>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000256">
        <property type="protein sequence ID" value="KAG0019871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005267">
        <property type="term" value="F:potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003929">
        <property type="entry name" value="K_chnl_BK_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013099">
        <property type="entry name" value="K_chnl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047871">
        <property type="entry name" value="K_chnl_Slo-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003148">
        <property type="entry name" value="RCK_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10027">
        <property type="entry name" value="CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10027:SF10">
        <property type="entry name" value="SLOWPOKE 2, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03493">
        <property type="entry name" value="BK_channel_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07885">
        <property type="entry name" value="Ion_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22614">
        <property type="entry name" value="Slo-like_RCK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0630">Potassium</keyword>
    <keyword evidence="5" id="KW-0631">Potassium channel</keyword>
    <keyword evidence="3" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="77"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="152"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="215"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="249"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="274"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="512"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="domain" description="Potassium channel" evidence="15">
        <location>
            <begin position="233"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="RCK N-terminal" evidence="16">
        <location>
            <begin position="316"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="domain" description="Calcium-activated potassium channel BK alpha subunit" evidence="14">
        <location>
            <begin position="454"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="domain" description="RCK N-terminal" evidence="16">
        <location>
            <begin position="849"/>
            <end position="960"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="629"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="805"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="966"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1038"/>
            <end position="1072"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1164"/>
            <end position="1204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="629"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="644"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="812"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="826"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="975"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1044"/>
            <end position="1072"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1175"/>
            <end position="1190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00034430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF03493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF07885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF22614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0019871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="19">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1327" mass="149254" checksum="D87333A1AC8370E2" modified="2023-09-13" version="1">MVVRVNRERLARQESFRSVTAASLVSSYPASISARRNHYHRQNSFGAQPGRLHEFFYWLKELAVLPDSTDEKFTSTVLNVINVVVDTVFCILYMVEANNLTRPPGYESHWLYVQRSIPFWHLLVAIATYNFITVVISIIFSESKMSSIRSGRHIVSTFVALPFIISIFLKDGHQLYVPYFLQSFALISRIQQALNFYIDIGVSDLPMDPLKSKTIIFGLYIITLIYCAISAFQVAEYDQLLGSEDHNDLLKLLYFVLITMSTIGYGDVTPKNQLGYAVVILIIVTVVTVFPWMISGIMDALAQAKAGEGIFKSGGHKFMIISGSLHSAQKLANVLNGFWFTNKEYTNAPFKIVILGLSEPSKDIQALLQSARYKNRVVYLKGTPLESKDLDRIQARHAEGIFIIADRNSLHSPQEEDRHITLSTLAFRNVSDAGIYTYNLLPETEMYQKIAATQVVCADELRQVLLAFNCLQQATATLILNLLHQHRPSETFDEAWEAEYDDSLGNEFYISYLNPIFVGMPFGFVSWFLYRRFQVILFGVRIRLQSGEYHTALNPGKDYCFRHNEQCIFIAQNPTDLDDIKELDEKHLENFLQHLHQTQEEDIKTIGLDYHAKNFSKALLTLMPNTRFHGKQRKRRTARRSMHSDSTNSYTRSVERSQLQSSMPTIANEDDEIDVEPEVSLMSGTEDSGAELGANEPLSPLAAVSEPIIENLTEDALPASHPGRGPALQTRYDPLTDKAEEDKLMNMRFQDDESDNLRIGYPAAPFPGAKMPLCTLLDDQNGERRVSDMIISDWNDVLKQRREKAAQKLIPTSESSTGGESASKPRLNSTEGETSKLNSASSKHDQELGHILVCSPNYDIFRLVCTLRSAHLKQLQDIVVLCSRQPNANEFKVLRSFPRLYFLIGDCLSRDDLERGAITKSSKYLFMRHPENAGVDGSFFDSAAVINRILVQQIFSDAQIAKVSRPRRVNDRSRATPSSATNDSICDPIAEPSLMMPTTKKAVSLQSLNEGPQCVYELVEERSVEFLQIRKTEVSIREKDHNRYTPTGPDSGNTPIESFGPESNSGYYGFPQQSAQRNRSALSSGSLDFYHNPIYASGGVLVGGLLDHVLYQLYSNPSILQLIKLLCGIRTKADVKRDFHLFKQYGAGCHLECIPVPDGFGVQTLRPKHQHENSGRSSSSSSSSGSEGSGNDQAESKSRNKKRIKKLESTLSKAASLGKQKISELFLHDNHRHHHHHGRNNSGSSDDSIDSDYIYDNRHKNFLHLYEHLALDQGVIPIGLLRLQGDDPKTVHLGIGGSSRCYTITNPLLDTIVLDTDQVFVLTRDCH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2H7</accession>
    <name>A0A9P6T2H7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glucosamine-6-phosphate isomerase</fullName>
            <ecNumber evidence="4">3.5.99.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Glucosamine-6-phosphate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">GNPDA1</name>
        <name evidence="6" type="ORF">BGZ80_004675</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:12172"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:75989"/>
            <dbReference type="EC" id="3.5.99.6"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.99.6" evidence="4"/>
    <dbReference type="EMBL" id="JAAAID010000236">
        <property type="protein sequence ID" value="KAG0020170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2H7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004342">
        <property type="term" value="F:glucosamine-6-phosphate deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006043">
        <property type="term" value="P:glucosamine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006046">
        <property type="term" value="P:N-acetylglucosamine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019262">
        <property type="term" value="P:N-acetylneuraminate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01399">
        <property type="entry name" value="GlcN6P_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006148">
        <property type="entry name" value="Glc/Gal-6P_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004547">
        <property type="entry name" value="Glucosamine6P_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018321">
        <property type="entry name" value="Glucosamine6P_isomerase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00502">
        <property type="entry name" value="nagB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11280">
        <property type="entry name" value="GLUCOSAMINE-6-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11280:SF5">
        <property type="entry name" value="GLUCOSAMINE-6-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01182">
        <property type="entry name" value="Glucosamine_iso"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01161">
        <property type="entry name" value="GLC_GALNAC_ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucosamine/galactosamine-6-phosphate isomerase" evidence="5">
        <location>
            <begin position="8"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0020170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="167" mass="18813" checksum="5FA14F968F3E679C" modified="2023-09-13" version="1" fragment="single">MRLVIRQDYEAVSYHVAEYVKERIREFAPTASKPFVLGLPTGSSPIGVYHNLVKFYQAGELSFKHVVTFNMDEYVGLPRDHPESYHSFMWNNLFKYVDIPPENVNILDGNAVDLDLECQLYEEKIAAVGGIELFLGGIGPDGHIAFNEPGSSLNSRTRVKTLAYDTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2K9</accession>
    <name>A0A9P6T2K9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cytosolic arginine sensor for mTORC1 subunit 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">GATSL2</name>
        <name evidence="4" type="ORF">BGZ80_003986</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000209">
        <property type="protein sequence ID" value="KAG0020562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2K9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046394">
        <property type="term" value="P:carboxylic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2130.10">
        <property type="entry name" value="VC0802-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040778">
        <property type="entry name" value="CASTOR1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027795">
        <property type="entry name" value="CASTOR_ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051719">
        <property type="entry name" value="CASTOR_mTORC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31131:SF6">
        <property type="entry name" value="CASTOR ACT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31131">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13840">
        <property type="entry name" value="ACT_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18700">
        <property type="entry name" value="Castor1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="ACT-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CASTOR1 N-terminal" evidence="3">
        <location>
            <begin position="9"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="CASTOR ACT" evidence="2">
        <location>
            <begin position="74"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="CASTOR ACT" evidence="2">
        <location>
            <begin position="272"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="204"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="338"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="345"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="372"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF18700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0020562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="415" mass="45609" checksum="45A86A4684975549" modified="2023-09-13" version="1">MNVDILPFRLQLASLDKSAIPRCTYQLMKLVLFPSGPRHFFSYAETDKEVSLILDESYVSGFPKGTLRVCSVIWRAVQIEPGESGLASDEVISRVSKPLADINVSIMQISTYDADFTLMPECDLQRALECLANILSISNSPFEDLGLQPSDLNSWEKSYPMSPSGVASLHDALLLDPSARERKFSLGGDSGSGVKAELDPSAISSLSLNDPEHSPKGSQTVKKARHPFDANYPHRADRFFSFTRTDNTLSMIMDDATMNLFPENSLNTHAGDWRLIAIGDGPLGFDECGIVSEFSRLLSVNGIGLFYLSTFSSDYIMVSDQDFEQAVACLRETARASDEEASVSIDPSRSTSNQKNALEDADLHSSGSESEIGSESEPESESFSEVDPEEYDDMDAKRDDYDDEVEIVFCGEGVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2P8</accession>
    <name>A0A9P6T2P8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Glycosylphosphatidylinositol anchor biosynthesis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">GPI8</name>
        <name evidence="8" type="ORF">BGZ80_003901</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000206">
        <property type="protein sequence ID" value="KAG0020620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2P8"/>
    <dbReference type="OrthoDB" id="192611at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042765">
        <property type="term" value="C:GPI-anchor transamidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003923">
        <property type="term" value="F:GPI-anchor transamidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016255">
        <property type="term" value="P:attachment of GPI anchor to protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1460:FF:000003">
        <property type="entry name" value="GPI-anchor transamidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028361">
        <property type="entry name" value="GPI_transamidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001096">
        <property type="entry name" value="Peptidase_C13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48067">
        <property type="entry name" value="GPI-ANCHOR TRANSAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48067:SF1">
        <property type="entry name" value="GPI-ANCHOR TRANSAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01650">
        <property type="entry name" value="Peptidase_C13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500138">
        <property type="entry name" value="GPI8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019663">
        <property type="entry name" value="Legumain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00776">
        <property type="entry name" value="HEMOGLOBNASE"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040245191" evidence="7">
        <location>
            <begin position="22"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="318"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="166"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR019663-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0020620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="398" mass="44985" checksum="C96C9206B130871D" modified="2023-09-13" version="1">MRPGTILKYIAASVCIASTLAISVTNNQEDVEGFFNKNKSGSGHTNNWAVLVCTSRFWFNYRHIANTLSMYRTVKRLGIPDSNIIMMLADDVACNSRNIFPATVYNNRGRYLDLYGENVEVDYRGYEVTVENFIRLLTGRVTKETPRSKRLLTDDQSNIFVYMTGHGGEEFLKFQDAEEISAYDLGDAFQQMYEKKRYNEILFMIDTCQANTMYTKIHSPNILATGSSKLKESSYSHHDDPDIGVAVIDRFTYYVLEVLEKIDMQSKATMKDLFDTYDPALLHSTPGVRDDLFKRPLDQVLLTDFFGNVQNVELTELNDQASSQTEIEPAPEEAGEPQVMEPQISKENHSSRATQTSRHHDHTFEIGDPSRSQTMRYVAFVALSAILGGALFAGSSVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T319</accession>
    <name>A0A9P6T319_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GST N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_002813</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GST superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000171">
        <property type="protein sequence ID" value="KAG0021245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T319"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44051:SF8">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE GSTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44051">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13409">
        <property type="entry name" value="GST_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="2">
        <location>
            <begin position="8"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0021245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="241" mass="27798" checksum="AE7871A235B3AC42" modified="2023-09-13" version="1">MSSASNIPSLFLLNRNYSSWSLRAWLVMRAFKIEFETVMLIVGTPEIPDLNTPAADELMLTAGPTSKVPALHVKRESGEKHIVFETLAIIEYLAEDCPLLWPTERLDRAYARSLAAEMATSFAPIRSYSMNIRQRHAFDPELYNDKAEKDIRRLSSIWDDLRSKAATKEADEGYLFGRFTALDAMYAPVMFRLRSYDLIPKVQGKHAAAYVERILSNEYVMEWEELSKQEKEVIPRDELYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3A6</accession>
    <name>A0A9P6T3A6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Inorganic pyrophosphatase</fullName>
            <ecNumber evidence="4">3.6.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Pyrophosphate phospho-hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">IPP1_1</name>
        <name evidence="12" type="ORF">BGZ80_001964</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>diphosphate + H2O = 2 phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24576"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="EC" id="3.6.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.1" evidence="4"/>
    <dbReference type="EMBL" id="JAAAID010000147">
        <property type="protein sequence ID" value="KAG0021656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3A6"/>
    <dbReference type="OrthoDB" id="1608002at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004427">
        <property type="term" value="F:inorganic diphosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006796">
        <property type="term" value="P:phosphate-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00412">
        <property type="entry name" value="pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.80.10:FF:000004">
        <property type="entry name" value="Inorganic pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.80.10">
        <property type="entry name" value="Inorganic pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008162">
        <property type="entry name" value="Pyrophosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036649">
        <property type="entry name" value="Pyrophosphatase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10286">
        <property type="entry name" value="INORGANIC PYROPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00719">
        <property type="entry name" value="Pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50324">
        <property type="entry name" value="Inorganic pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00387">
        <property type="entry name" value="PPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00040300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0021656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="293" mass="32881" checksum="162AF6EE7E334C0B" modified="2023-09-13" version="1">MSAYSTRVIGAPNTLEHRVYIEKDGAPVSAFHDIPLYANEAKNVYNMIVEIPRWSNAKLEISKDEEFNPIKQDVKKGKLRFVRNCFPHKGYIWNYGALPQTWEDPTHIDKDTNARGDNDPLDVCEIGEQVGYTGQIKQVKALGVMALLDEGETDWKVIVIDVKDPLADQLNDIADVERVFPGLIDATRDWFRIYKKPDGKPENEFAFNGAAKDKAYATKVIEETNVAWKRLISGEIPAKAEAYDVKVSNLHVQDSPHRVAADHEVVKSIPAASAKPAAPIDASIDKWFFTSNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3Q2</accession>
    <name>A0A9P6T3Q2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_000397</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. GCN2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000108">
        <property type="protein sequence ID" value="KAG0022374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3Q2"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004713">
        <property type="term" value="F:protein tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110031">
        <property type="term" value="P:negative regulation of G2/MI transition of meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00180">
        <property type="entry name" value="PKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050339">
        <property type="entry name" value="CC_SR_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042:SF190">
        <property type="entry name" value="MITOSIS INHIBITOR PROTEIN KINASE MIK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="4"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="284"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="371"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="289"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0022374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="500" mass="55578" checksum="387060C414C976C5" modified="2023-09-13" version="1">MRQYLLSRRAMCGMTCKDLLQTKETTDDANTFVCAAKCLSFNTDSQSAGLEEAEILKRLHSHKAHHPGRQYLVDYFGLYDQTTKQAISITDSVNHDLVTQSETQDSKWILLLEYCQQGSIWDWIRQNPEKVGFRQWLTWALQLMQAVDCIHEAGLVHHDIKPHNILLDSSLDAKLSDFGAGRFLSTNADDMKSIDTSSSATTFMLEEGHGRGTPPYAAPEMFASASDARYGQGIDIYSLGISLYVIGLTAQEPFHKVKNPTEMIIWIKKGGFWLIEEQSWIHDRGPVPKTTSSSRLPTSSVAQTLAQSSHAHGQESKLKPGGLSRLSRLSASSQLLTPNLPPINTKLSYERSACTPNSACSLNSPSSLLGPHQSHLCESPTGFSPERSMRSSLPSTPVSPLPLPSPIARSQTPRSSIRKEEHRRSGEIVMRFLNGEVVQPQVIQLLKDMCNSDPSRRPSAKMVLQRLQMMESQLNIDLDVEEEGLYAGMDVDMPEDSHAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T4M7</accession>
    <name>A0A9P6T4M7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_002777</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000017">
        <property type="protein sequence ID" value="KAG0024462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T4M7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005850">
        <property type="term" value="C:eukaryotic translation initiation factor 2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001731">
        <property type="term" value="P:formation of translation preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050543">
        <property type="entry name" value="eIF2G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42854">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 3 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42854:SF3">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0024462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="76" mass="8518" checksum="6706461A0653A52B" modified="2023-09-13" version="1" fragment="single">WQSVGHDILMTTILNGTAVMDAALPLVTTNEFSPQHQTSERLVAIEITKLEHIVILQNKVDLIKKNAALDHYQNIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T4N4</accession>
    <name>A0A9P6T4N4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CASTOR ACT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008909</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000005">
        <property type="protein sequence ID" value="KAG0024751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T4N4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046394">
        <property type="term" value="P:carboxylic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2130.10">
        <property type="entry name" value="VC0802-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027795">
        <property type="entry name" value="CASTOR_ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051719">
        <property type="entry name" value="CASTOR_mTORC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016540">
        <property type="entry name" value="UCP008459"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31131:SF6">
        <property type="entry name" value="CASTOR ACT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31131">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13840">
        <property type="entry name" value="ACT_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF008459">
        <property type="entry name" value="UCP008459"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="ACT-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CASTOR ACT" evidence="1">
        <location>
            <begin position="70"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0024751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="140" mass="15823" checksum="CF78F2A01E212AE0" modified="2023-09-13" version="1">MKLELELDPLPYTVHRLPPSTPASVYLPLIDDQVWYTITKTPEEISLVISHDYADTKENQLLLNDGEHKISPDWRCFKVKGPLDFSYVGIMANLSGALAENKISLFVVSTYDTDYILVKKDKALDAKQVFENIGHSVDVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T4Q1</accession>
    <name>A0A9P6T4Q1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">mRNA decay activator protein zfp36</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ZFP36</name>
        <name evidence="8" type="ORF">BGZ80_003094</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000018">
        <property type="protein sequence ID" value="KAG0024426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T4Q1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045877">
        <property type="entry name" value="ZFP36-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12547">
        <property type="entry name" value="CCCH ZINC FINGER/TIS11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12547:SF18">
        <property type="entry name" value="PROTEIN TIS11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="211"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="211"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="89"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="248"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="422"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="107"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="123"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="257"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="422"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0024426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="464" mass="50781" checksum="D782D1E3F1DADDE0" modified="2023-09-13" version="1">MNSRENIHPYPLTHRHQKEQSVPTHSSYTAPSVIDLFRRLSNPTKLSPEYCSSQDTGMDLVGSVVFSVNPPSPLESDLCADDQESILRTWHTSGPSVEDSLKGGSSEARDKFEPDVMDHGIRTPSSSTETTQSNANIRTITQPSRSAGSLSSLPHANKGEFPGKRSHGGPRRSSSNDTHRKSELYKTELYGDNCQFAHSTQELQHVTRHPRYKTQFCTSFQSQGYCKYNDRCTFIHHPDEARVLLTPAPRESTSEKPTWSNSTSNTSPGSGAITPASGPETNNNERLRAFSDPGIGYTEVLKHSVKTVNATNSVAAAVGAPPQMLQGVPTALSPQTVDAQIGSVGRLNQDPTSFLKPLSKKVISHKSDAITSAVEALGHRLRAPDYTTPIHYLHGTCAPPVAGLDLSPRPATFMPTVTNSTWSNPLCQQDPANPWRETTNADDDEEWASKLAYYISTPQNDFDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MC86</accession>
    <name>A0A9P6MC86_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_008983</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010005079">
        <property type="protein sequence ID" value="KAF9991648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MC86"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9991648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="90" mass="10223" checksum="72C1178431F4C163" modified="2023-09-13" version="1" fragment="single">MLISCKEQERRGNLIGELIRLESKIAKHPEQFASLSSTKETLGLFIYRWFILGETAIVLEDEAQLVEAAFGRIKMLEGNARTVLDEPFVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MCI8</accession>
    <name>A0A9P6MCI8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Carrier domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_008851</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004950">
        <property type="protein sequence ID" value="KAF9991851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MCI8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043041">
        <property type="term" value="P:amino acid activation for nonribosomal peptide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1200.10:FF:000005">
        <property type="entry name" value="Nonribosomal peptide synthetase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF1">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="4">
        <location>
            <begin position="78"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9991851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="190" mass="21227" checksum="E522E149350D4ABD" modified="2023-09-13" version="1" fragment="single">ITVGEGNSKRLVAYVVAELTEGLVHTLHSHISSKLPEYMIPTAFVRLDMLPLTPNGKLDRRALPKPDVDSFVSQGYEEPQGEIEYTLAGIWSELLKVERVGRNDNFFMLGGHSLLAVQMIEQLRRINMEMSVRTLFNTPTLSALAQSLNKSNATTEAPKNLITRDTTKITPELLPLIDLTQDDIDLIVDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MD23</accession>
    <name>A0A9P6MD23_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Arm-like repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008278</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004439">
        <property type="protein sequence ID" value="KAF9993095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MD23"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056251">
        <property type="entry name" value="Arm_rpt_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23948">
        <property type="entry name" value="ARM_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arm-like repeat" evidence="1">
        <location>
            <begin position="220"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF23948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9993095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="305" mass="33408" checksum="C22DC72E75DC9FCE" modified="2023-09-13" version="1" fragment="single">AEHIFTSKKVKDPSLNKGIANAYHEYGRLLDDLGRHDKAKKSRSMAEKWGYVDVVSRHTGSRHPLGKNDTVSRLFLPTAALSVVAADLLVSPRVTAALSVAPSLAAALSVSSSVSVASGVATAIYRDNSKTDVVQLSHQDHILHSTPAKANNGKPTPSKDVMHIPRKIFDQNIVPPITKYTLPEPNGRITNTPQLAYCLCLLHPSMILKEELDQNERHWLQAKVSDPDEHERLQTIATDVIRAFVQEGLKKPGVVAEVVSLSAVLGQDDFRKLLQIFVDGINQSWLLDVHLLNGLALLIRNSPQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MDR2</accession>
    <name>A0A9P6MDR2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008169</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004357">
        <property type="protein sequence ID" value="KAF9993358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MDR2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9993358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="177" mass="19864" checksum="9D5194E7A16E5A47" modified="2023-09-13" version="1" fragment="single">PSSRPVSVPDSFKRNKWKAYVEREYSKPEEETSKKKKYKPSRRIPSDRYDVVKAMTKAHQAATLTVGSVTANREILDGLTEDENTAIGKLIQDCVNVGNFVKREAHIALASYIKNKGKEGLENIRKVLLKHPDNIEVMKKTLNLAVPTAPDFSGPCLSTFVTVRGQEANATKKHWVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MDX0</accession>
    <name>A0A9P6MDX0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_007894</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004131">
        <property type="protein sequence ID" value="KAF9994201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MDX0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9994201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="139" mass="15789" checksum="989AF84BB4A26461" modified="2023-09-13" version="1" fragment="single">DLYNVLLSRIPKDRLKLGKRLVSFQHINNINNINKGESPTLCSTLSQPSERVMVRCSDGTYYYGQVLVGADGASSAVRQSLFRQMKEEGTLPKVDQEEQQLRQVSLLGVTNPLNPKKHPDLRDSFSNFKIILHRNSPYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MFS8</accession>
    <name>A0A9P6MFS8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_007054</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003548">
        <property type="protein sequence ID" value="KAF9997215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MFS8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990234">
        <property type="term" value="C:transferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.80">
        <property type="entry name" value="E3 ubiquitin-protein ligase SopA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847:SF637">
        <property type="entry name" value="WD REPEAT DOMAIN 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05729">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141571">
        <property type="entry name" value="Pentapeptide repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="NACHT" evidence="4">
        <location>
            <begin position="14"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="524"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="566"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="608"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="638"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9997215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="638" mass="72535" checksum="F27508E2B0E736D9" modified="2023-09-13" version="1" fragment="single">MSKVQEFLQSKKKVFLLLGDSGAGKSTFNRALEINIWEKYGKDETRIPLFIHLPLIENPERNLVTKQLQILDFTETQIKELKAHHKFILICDGYDEIQQTKNLYETNQLNKPGGWQVQMVISCRTEYNGVDYKNQFQPTERNNGGKKEQFQEAIITPFSENQIQDYVKQYISLKNHQNMPSDDTYWELEEYQQALKEIPNLLELVKNPFLLKLALEVLPGLFSKNSKFSAAHITRIGLYDKFVSQWIERSEIRLRGMELSSHDNEHFQTLCRSGFTFCSISYLKEFATAIYDHQGGKPVVRYLEYRSQEDWKKSLFNNDGGRKLLRESIPLTCNVDQYRFIHESVLEYGLSLAVCEPNEDDENMESPSVTSRRMSAGSVQSFEEPFLMDDPALSNEQALLESPLGRINFVRHPSILQFLTERAQRQPTFKDQLRSIIEQSKTDKSVEIAAANAITILVRAGVQFNGADLQGIKIPGADLSYGVFDSACLEGADLRDVNLRNIWLRQANLRGAQMTGVQFGELPYLQQDSEVQCCAFSPDGKIFAVGTENGDIHLYETSNWKRIRSLNGHSEGVYDVAFSAAGDQIASGSDDRTVRLWDVDTGNSIQTLQGHTGWVMSVVYSPKGDQIASGSFDSTVRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MHK9</accession>
    <name>A0A9P6MHK9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006226</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003065">
        <property type="protein sequence ID" value="KAG0001155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MHK9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="37"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="210"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0001155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="471" mass="50653" checksum="4C186EE01552CED2" modified="2023-09-13" version="1" fragment="single">DSGTLVAPPTALSNTVTNPTSINRKNTTAALLSVSSPTTPSPTTTTTTTTTTTTATTTTNPTNKRPTLNPTLSAPSSSPTSYKDLVAQFTAKAPQPYGFIPPRKKRTKGLVRSNSTSSVSISTTATAKKTCVPPLSPIETSSNAVELLPTFLRRKDSPDCHNENAVQSQIIQPLFHSLQSLLPESTSSSTRLGFWANLKAHYFAATTTSFSWSSSSSDSGARNGHRSAAKTSAGPEEFSPPIALRLSNSTPVAAVDATAPHSASLTLTDAFLSLPNLATSPSQGYHGSVNFPVSVAAMDKFKPVRSDTIPLKTFTYHETPVIERPQPLPLPLPLPPRSSLAKKTANTLAPPIPLTKSDANVVESSDKDTSLLDPLPRHLATRETRSNTDYLRMMAPELRMIRARKLVSPLKPRGFLPRRKDPFRRVKSPLSNCIEIPREEDDHPLNDVMVGSWSSVSSSDSFFSSSSSEYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MIZ8</accession>
    <name>A0A9P6MIZ8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">3-beta hydroxysteroid dehydrogenase/isomerase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005656</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002786">
        <property type="protein sequence ID" value="KAG0004194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MIZ8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006694">
        <property type="term" value="P:steroid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002225">
        <property type="entry name" value="3Beta_OHSteriod_DH/Estase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01073">
        <property type="entry name" value="3Beta_HSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3-beta hydroxysteroid dehydrogenase/isomerase" evidence="1">
        <location>
            <begin position="8"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0004194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="102" mass="11412" checksum="36E337FE3DD5908C" modified="2023-09-13" version="1" fragment="single">MAPQPTVLVLGGVGFIGRHFVAHLVENDLAAEIRVIDKVLPQTAYLNKRFQAAFTKVEFMQTDLSNTIPPEKFDNIYTRADGSSFDYVINFASETKFSQLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MKE1</accession>
    <name>A0A9P6MKE1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Transcriptional activator HAP2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_005227</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002594">
        <property type="protein sequence ID" value="KAG0006550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MKE1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001289">
        <property type="entry name" value="NFYA"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51152">
        <property type="entry name" value="NFYA_HAP2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="18"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="63"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="21"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="34"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="65"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0006550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="105" mass="12422" checksum="8C9F9D77E9C26D27" modified="2023-09-13" version="1">MRRPRGPGGRFLTAAEIAAMQDKDRPDDYDGQHGDSTSAGYDNNQAAAYQVQHHRQQLKQEEELFQQQQQQKLQQHQHQQQQQQNQQQHQQQQQYHQRQAYETGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MKX0</accession>
    <name>A0A9P6MKX0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thioesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005346</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002641">
        <property type="protein sequence ID" value="KAG0006108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MKX0"/>
    <dbReference type="OrthoDB" id="329835at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001031">
        <property type="entry name" value="Thioesterase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00975">
        <property type="entry name" value="Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioesterase" evidence="1">
        <location>
            <begin position="55"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0006108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="288" mass="32011" checksum="BA5D89639AD6833B" modified="2023-09-13" version="1">MAGQVRSRLGLNMQLHSLFEAPTIAAIASRIVQDDVKHDTAFDVLLPLKPQGCRPPLFCIHSVFGFGWSYVALSQHLHPDQPLYALQSRGIGGNGELAETFDGMVQDYINQIQRVQPKGPYHLLGWSFGGSIAHSMAAKLEKRGEKVSLLALMDSITTYSAESDDVDVDHDADVYTEHFARSNTINTLDEGKALWTKARDVVRNNIVISKQFSPSIYSGDMIFFQATKSSPVIDVSTWEPFTQGAITKHQVECAHLEMDTSKPMELIGRVLAMKLEELHQQSLDVKDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MM64</accession>
    <name>A0A9P6MM64_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">Vacuolar fusion protein MON1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">MON1B</name>
        <name evidence="8" type="ORF">BGZ80_004370</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for multiple vacuole delivery pathways including the cytoplasm to vacuole transport (Cvt), autophagy, pexophagy and endocytosis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endosome</location>
            <location evidence="3">Multivesicular body membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 3">Prevacuolar compartment membrane</location>
            <topology evidence="1 3">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Vacuole membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the MON1/SAND family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002231">
        <property type="protein sequence ID" value="KAG0007682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MM64"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035658">
        <property type="term" value="C:Mon1-Ccz1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032585">
        <property type="term" value="C:multivesicular body membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043972">
        <property type="entry name" value="FUZ/MON1/HPS1_longin_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043971">
        <property type="entry name" value="FUZ/MON1/HPS1_longin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043970">
        <property type="entry name" value="FUZ/MON1/HPS1_longin_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004353">
        <property type="entry name" value="Mon1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13027">
        <property type="entry name" value="SAND PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13027:SF7">
        <property type="entry name" value="VACUOLAR FUSION PROTEIN MON1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19036">
        <property type="entry name" value="Fuz_longin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19037">
        <property type="entry name" value="Fuz_longin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19038">
        <property type="entry name" value="Fuz_longin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01546">
        <property type="entry name" value="YEAST73DUF"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0072">Autophagy</keyword>
    <keyword evidence="3" id="KW-0967">Endosome</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="3" id="KW-0926">Vacuole</keyword>
    <feature type="domain" description="FUZ/MON1/HPS1 first Longin" evidence="5">
        <location>
            <begin position="302"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="domain" description="FUZ/MON1/HPS1 second Longin" evidence="6">
        <location>
            <begin position="462"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="domain" description="FUZ/MON1/HPS1 third Longin" evidence="7">
        <location>
            <begin position="591"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="115"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="208"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="35"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="66"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="265"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU367048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF19036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF19037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF19038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0007682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="706" mass="78215" checksum="EB15045AE01BC5EA" modified="2023-09-13" version="1">MSTPGSSSTNGANDATASSSHAGSSNILLPAMPSPYSSPLQAATSPRLMPSKSRPTTALVFDQHAQQQQQQQQQQQQDTESLSSDEFVLSSSSATTKDNSKKGIAATMYSSTRALNDLAGPTQQETQSRRLSGLNQDVNSDSSDEPDDRLTDTESEQGDRTGTPIIAGHSQVHTAGMDHGTITALQSLREIDEHDKDGRRIHGIESRFRGIDLASDQDQNSEAGDTSDPPPGAALNAGQIQDKLKILRPKPNNSNNTAKPRLQRADSTNSYDSDDISNNYGGYQKRFGGEDHTTHSWTAHRKHFFILSSAGKPIYARYGDESRISSYMGVIQALISFFADNDDSIRCINAGQHKFVFLLKAPLYLVCVSRSGESESQLREQLGYLYAQIISVLTHSQMTKIFEQRNNFDLRGLIGGTEIFLDSLGKFMNTYPGFMLGAVQCLTMPRELRDKVGAVLGRAKCKPLLYAILLTPTQLITLLRPRTHSMHPSDLHLIFNLLSGSTTFESSESWTPICLPKFNNKSFLHAYICYIAKKVCMLLISPDKDSFFEMSSVKQKVVEGLEASGMLASLESYAAAGSLGGFSVGDTGIPGLRHFLYKSRTNVQFTMPELAEPYTTLGARKRLLYQYHHMHERMHRKTRPLKLLFHVGQHETMLGWITPSFELYVAFGPFVSKSAVVLMSNKLLKWIRKQEDSLLILNSPSFEKFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MM93</accession>
    <name>A0A9P6MM93_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pentatricopeptide repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004442</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002266">
        <property type="protein sequence ID" value="KAG0007618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MM93"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050667">
        <property type="entry name" value="PPR-containing_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47939">
        <property type="entry name" value="MEMBRANE-ASSOCIATED SALT-INDUCIBLE PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47939:SF5">
        <property type="entry name" value="PENTACOTRIPEPTIDE-REPEAT REGION OF PRORP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="277"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="508"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="824"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="295"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="830"/>
            <end position="849"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0007618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="981" mass="112102" checksum="A130E60B10C0B4E7" modified="2023-09-13" version="1">MRSSAIRCMLAGPQLSVAFRTEQQLLQARAADNFWKQCFKRAYSRSMFSKDRQLITTFCPTHSSEKRIPSPCLATGKHHPPRSRHSRPYTNAATATVTFSRPGAKPITNGSTLAPVANPTPTPVSSTESRSAEVIMKRLDQALRDQDLKTAYAEYLIMRQRTFPTDLTHLWYRCQRRLVQLFHRTRLEVLSNDHAHLFTRKLKQLDHNRRVVLRDIHQRTLKTSKQAETIAKLVNALGKSKAMVQHSYLTDSKTKLDDWREALRVLEDWTALKPHGVSTPASGLSSDAEGEADESSTAATDATAGSPSSYQLENKIMEKDLATWLSKLMRRLVYSHTFLVRSMLDTIPSQYGIQTTTEMYIALLEYYAMFGKDGCKDTLDIIHKMGSQGIDWRQEPVIYDYILYALSHESGNVAQADKVIEKMLASDLVPREETMKAAILCAARSGDLEACSRYIQRMHHDWNLSITERMKAIMLYACAKRGDFEGTLEILGQLSRSGKLVEPKVDIPRTHRRSRDTDSITSTSASALSPKDTIEKSLDAQDIINNSNVLLTLINQTHSRRGGKKQLSQEFVKDEVSKVLELFTVITRDQDRVDTQFYTIMMHYLSSLPSPLPGMMYLYKEMQASENAKPDNVTYKIMMEACAEQMDMDQGRRLWGDLKGAKVIQDCHIRASYVKGWGRTGHLDTAEAIARAGLLAQEQLEKDRFQNQIVFAIRNKKRRSLGLPELEKPPRLPKRQRTGEMINLTVLHELMKAHRQHNNPARVYELYREIESGKWGRKIRPNGFTLSIVLGACASGTATVELVDRSIELVDHVLEIKRRQRQQYYKGSDVEDADEGRDNDDDNNGDEAYPDGRHYRRRIHDLLGSESVPDKSQLPILSDVNYQLYFTMLGRHHRQHKIVEVWDDMMDSIENPPSHLTVNLVTEALENVQWGARPIKQILRQLRERWPEIDWTKVDWGTRSGPRSYRVEVDDSVGAGGRFWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-06-18" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MN85</accession>
    <name>A0A9P6MN85_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Atp-dependent bile acid permease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BGZ80_003635</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001979">
        <property type="protein sequence ID" value="KAG0008261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18596">
        <property type="entry name" value="ABC_6TM_VMR1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18604">
        <property type="entry name" value="ABC_6TM_VMR1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000565">
        <property type="entry name" value="ABC bile acid transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000825">
        <property type="entry name" value="ABC bile acid transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000006">
        <property type="entry name" value="ATP-binding cassette, sub-family C (CFTR/MRP), member 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF353">
        <property type="entry name" value="ABC TRANSPORTER ATP-BINDING PROTEIN_PERMEASE VMR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="131"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="195"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="224"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="335"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="376"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="471"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="494"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="570"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1018"/>
            <end position="1037"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1128"/>
            <end position="1148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1210"/>
            <end position="1227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1233"/>
            <end position="1250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1319"/>
            <end position="1337"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="13">
        <location>
            <begin position="339"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="671"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="13">
        <location>
            <begin position="1122"/>
            <end position="1369"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="1409"/>
            <end position="1646"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="947"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="96"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="951"/>
            <end position="963"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0008261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="16">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1669" mass="186215" checksum="4B2ABD97E6E5E53E" modified="2023-09-13" version="1">MAFAPGPIAPGPIAPGPIARFCGNDSAEAPWIDNDFTPCFHESVLDAGIPLLFAAVSFLTIIGTAIYKHVRKNHSGDQSGYLPIPAQEDSIAGLDTDMDDQEDLDQDNTLSNSATHLGQVSSGRRISIRDAIKTLGTFVSLAISIIWMVQRSNEEKSSYLYIAPLVSTCVWAYISILTVFHLLRPLNPLISLTPHFSTFFIVNVPIALFRLRTQVIHRTSHLEFILASIYFADAIILAVLALTSTKSTRALVAKPGQRVPCPETYSSISALALFSWADPLISLGFRRAMNKDDIWDFRLSDYSSAVIHHFRQSILATRKNYPFIVRLVINFKRRITVQVFWAVCWGFLTFVGPFTLERVLHFISNKDTISAEWGYIYVFSMFFGMLCATIAQSQMLWHGRRISMQLRSIVVGEVYAKALRRKDRAGQTQANNDSDDESENENEPFTYGAINTMISNDTSEISEASAYLQDIYILPLQITLAILLLYRILGWPALTGVLTMACFIPFNLYLTKKVEKIQDELMRATDKRSELMNELLQAIRIIKFFSWERNFYGKVDKARELELSKLRLRFTWWIFGTALWFGTPVVVTITTFFVYTKVAGNSLTAEVAFPALALFNVLRAPMDAFPEMLSLCLRAKVSAARIDRFLDEEEVLVYANANAKPRKNLPTDPIIGFKNATFSYAGKTEQDAANAAHHAGETLSGHYFELKDLNLEFPVGELSVITGPTGSGKTSLLLSLLGEINPVKGQAFLPRRDSHDINPVTGLTNGIAYVAQQAWLQNNTVRNNILFGSPFEQRRYDQVIEMCALRRDFEILEYGDETEIGERGITLSGGQKQRIALARAIYSRAGHILLDDCLSAVDAHTAKWLFAKCLMGPLMQGRTRILVTHAVSLTLRGAAHVVVLRNGTVVANGTPNQILDSGILGDVTHEDQTFEEHSTDDHTVAVIEETEDESGANTPVASSSVSLTAAGKMKKRTGDDDSSTDSTIPAKEKKKLIVDEGKVDGSLSWNVYKLYFGSMGGIPYWVFLISAFIVMQVFQVASDTWLRFWARASERHNDDGSTYSAASFAASAVPPFASSASSIATNMSSLLMSFACQYRSGHTYFGNNPVRSPIPDGFSTFEDKPGSQLGDLNYYLGIYALLSFLYIFTIMCRQAVQYKGSLTASRSIHRRLLSRILNSPVRFFDTTPLGRIMNRFTKDIETVDQEVAPIASNLMFDLLGTLTVVAVITYITPQFLFPAFLITILFIVMATLYLRSSRELKRIESITKSPIFSHFGESLSGVATIRAYGQEKRFQRENLELLDEHNRPFFYLWVCNRWLSIRVDVLSALVSFFAGLLIVINRNSVDAGAAGLSLSYSLTFTDHVLWLVRLYSNNEMNMNSVERVREYMDLPQEPPAVIEGCRPPPGWPNNGEIKVENLVMQYSPDDPPVIRDVSFHIRPREKVGIVGRTGAGKSTLAVAFFRFMELTAGRITVDGIDISNLGVHDLRSSLTIIPQDPVLFIGTIRTNLDPFNEHDDAALWATLKRVHLISGDGTESNSFGNLDSEVQENGINFSQGQRQLIGLARALLKQSKIIILDEATASVDHDTDARIQATIREEFKESTLLTIAHRLRTIIDFDKVLVMDHGRVVQFDTPWNLIRTEGIFRGMCQRSGEFELLAEMAAIAEANANSSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNK0</accession>
    <name>A0A9P6MNK0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">DNA primase large subunit C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BGZ80_003494</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic-type primase large subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001928">
        <property type="protein sequence ID" value="KAG0008397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNK0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005658">
        <property type="term" value="C:alpha DNA polymerase:primase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006269">
        <property type="term" value="P:DNA replication, synthesis of primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07322">
        <property type="entry name" value="PriL_PriS_Eukaryotic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.80">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058560">
        <property type="entry name" value="DNA_primase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016558">
        <property type="entry name" value="DNA_primase_lsu_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007238">
        <property type="entry name" value="DNA_primase_lsu_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10537">
        <property type="entry name" value="DNA PRIMASE LARGE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10537:SF3">
        <property type="entry name" value="DNA PRIMASE LARGE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04104">
        <property type="entry name" value="DNA_primase_lrg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26466">
        <property type="entry name" value="DNA_primase_lrg_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5" id="KW-0235">DNA replication</keyword>
    <keyword evidence="9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0639">Primosome</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA primase large subunit C-terminal" evidence="11">
        <location>
            <begin position="239"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="434"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="448"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF04104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0008397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="479" mass="55160" checksum="EB3AA230E357F6A6" modified="2023-09-13" version="1">MFRQETRKSRQKEKLLAGAGITYNEAPYPTRLNFYVNPPTLEISIEEFEKFALDRMQVLTTLLTAQMRNLAPEQLKKTVDEALQKYMPIYRFEKESLRDQVEFLERQNLSWKKVSEDDKRLLKEQLKASHYKGQNVDQETYFEVDFERVTGLVGRRQVYVKGGKAYVPMADQVVLVLDEFKERLSNALEVTARALPRMEEDDRLMPVLNNINKQYLGREFTTSAVAGEIQAQDVDGLKVHMPLCMEHLHNELRREKHTRHGSRMQYGLFLKGIGLSLEQALLFWQMAFEKLTPDQFNKQYAYNVRHLYGMEGKRTDYTPYSCRHIIQNNAPGPGDHHGCPFRHFSAPNLRATLAGHNVDDFDTEDIMTLVAGKHYQIACTRYYEVTRAKMLNISTDNLKGGTLNAQGNSMVASQEIIEHPNQFFEQSFLLMKSRDSSSTGENGEPVDGQQSLQPTIKGQYSYKKAGAQISSQANHDMEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNU0</accession>
    <name>A0A9P6MNU0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NAD-dependent epimerase/dehydratase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003808</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002025">
        <property type="protein sequence ID" value="KAG0008145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNU0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050177">
        <property type="entry name" value="Lipid_A_modif_metabolic_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43245">
        <property type="entry name" value="BIFUNCTIONAL POLYMYXIN RESISTANCE PROTEIN ARNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43245:SF11">
        <property type="entry name" value="LD23561P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="1">
        <location>
            <begin position="9"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0008145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="271" mass="30496" checksum="6349FA7E17CB8FA1" modified="2023-09-13" version="1" fragment="single">IYEDRIYKLSINCAKEAVKRGAKVFVQFSTGDIYEGSGSASKEDSKTKPWNTIAEYKLKVDKELQEMEGLNVIILRPAVVYGVGAMGGLTPRLICGRVYMHEKKKMEFLWTKDLRINTVHVNDVAKAIWHTSNWYISNDKSGPVIFNLADDNDTDQEAVNTHIRAIFGIETGFQGTVVSQIAKLNMKDATEEINELHLAPWSDILKAHKITTSPLTPYLDQELLLNNALSLDGTKICTSTGFTYDHPKLTTESLKEVIADFQELGIWPRDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPC0</accession>
    <name>A0A9P6MPC0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Condensation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_003359</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001884">
        <property type="protein sequence ID" value="KAG0008507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPC0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043041">
        <property type="term" value="P:amino acid activation for nonribosomal peptide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensation_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF1">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Condensation" evidence="2">
        <location>
            <begin position="164"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0008507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="334" mass="36815" checksum="692CD84C550C443C" modified="2023-09-13" version="1" fragment="single">MTISKQWNALEDANLTRKHAAMNVENQLSQEIETITSMDIVDNSPFEFKNAEPIKIPVDESMAFGDSSGNDLSDLEVTSPTAVEDINGFDSSVFHVPAFVNGVKEQGPTHPLKPEIENDRKDGSPRTSVERVIPDSSDIIKPERNGHKMVPINESTGDERKIGHELQTRIDYWCKALADAPVLLGLPTDRPRATHQSVDYSHLPIRLDSQLTQLLKNLAQKHDVDLSVVLLSAWSAVLARLTSQDDIVVGHYDLVIDPHVTSTNHLNGNAITSANPLPLRMDLSGDLTTAQLLGRVSQTILAARAHQDIAFENIIEIMKTSSKEDHAALFQVAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPE3</accession>
    <name>A0A9P6MPE3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">GDP-fucose protein O-fucosyltransferase 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_003517</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the glycosyltransferase 68 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001933">
        <property type="protein sequence ID" value="KAG0008384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPE3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046922">
        <property type="term" value="F:peptide-O-fucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006004">
        <property type="term" value="P:fucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11296">
        <property type="entry name" value="O-FucT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019378">
        <property type="entry name" value="GDP-Fuc_O-FucTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045130">
        <property type="entry name" value="OFUT2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13398">
        <property type="entry name" value="GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13398:SF0">
        <property type="entry name" value="GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10250">
        <property type="entry name" value="O-FucT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0294">Fucose metabolism</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="20"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="308"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00026232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0008384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="521" mass="58525" checksum="B4BB737FD5CC909B" modified="2023-09-13" version="1">MKTLAGQGSNSRSLSLKTKILVTLIVIIIVSAWTLLSNIDVMDFDVNFENTNSFINGQNDTAPSVDLGPLEPAVSLLDRDTKYLTFLPFAGFTNQFISIEPAALIAKKLNRTLILPPIMSSYHDHDNTHQRWASLFNIPRFTHLTGIPVLAWDQVRPLTPAQRKVGRDQAVYGTYLDLSIQTEEWARVAENLTCEIIVNYGTPGNPINHSGMNFLWHFLFRPIPKQPPMKNEGENGLYVLDDIVTAYADNQDQLLVLSNAYKVRDDAHGSRLWDEIGSNLHFVPELMEYATLRVNEESRGDWGIEALVDDDPEEKPRSPEDEDIEPIIPPNMNPNATESGVTLDLSLSNMTAPLTRTPYIAIHLRRGDIWEKCKGKDMTRCLIPFDTYVDAVARARTNAAARGLHSRLPVIVTTDTTSEDDLRTIEQLGWHRMDHAKYGTAKLWGPFGEAMVDAAVLAHADEFVGSPMSTMTRIAARRQKSWYNRGMIYPGAPKKKGMRKRYLVSSESEWEANADAVSIVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPQ9</accession>
    <name>A0A9P6MPQ9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_002522</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001624">
        <property type="protein sequence ID" value="KAG0009311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1119"/>
            <end position="1141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="383"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="479"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1189"/>
            <end position="1247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1295"/>
            <end position="1545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="155"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="216"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="274"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="295"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="490"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="519"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="549"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="608"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="630"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="641"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="663"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1194"/>
            <end position="1203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1213"/>
            <end position="1229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1295"/>
            <end position="1312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1323"/>
            <end position="1333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1341"/>
            <end position="1353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1378"/>
            <end position="1405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1420"/>
            <end position="1431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1448"/>
            <end position="1457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1462"/>
            <end position="1476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1488"/>
            <end position="1526"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0009311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1545" mass="165028" checksum="EEDF9EDBA178FED7" modified="2023-09-13" version="1" fragment="single">MSPKPSEPQEARAQDGLKANTGTVIRYSREFLLECAKSPLVQRPEGLPPKSVWFGIKTVSAERIVLGPPKMSFASSSFSGLKKAEDGPSGFKKTLDSSRENRSPRGPPSALEQGFGRETIEKLSSHKLPKVTPKDITGLLSGMDRRRHDPSRLNSSTLTGSRTATSSTSSRLGSATRTSGQPMSTSNTSMNSSSSNGIGLGSKIQRSDAPEWMSYNPESENLANDGENNGEPQAFVDDIQAWKARMKEHEKREKEKETSNQSQRDNKDPRVPSRADSSSSWRSNALPSQNLEDPVENKKPDDTKNHPVLDKSLGRALLSNEPIQDIDIFFSPGGIDLTKPFDTSSAFDKFLSQHAVAISTFEESGQQKPGKADGSRFARFFTEDEPEPVKQVEQPSHSAQDMPGRQLSLDQLFQAHAPNSTATAPPPPPPPLGRMPSEAEILESMRVNKSLVAAKSVDNSEESADAFGFSKIMAALSKPPLGNAEPSVFGGSTSIQPQTDQPLSGGMDPSLPLTRPPVTAQTLQDPSIVTFQSKPTLLDTLMKQADNATTPSEPSQPVSSSVTSESSQTQGSGAATATTSPSTPSSDTSRPAHRPVQVAFGGGIPTSVYRQLSGKTDGQKSASPLIRPLSSANGMNTNGGSSPSLSSPSASSPRQFNPQAAVPSQQTPSHQQQSTPQASSNMQQSSQLGMHQQQQSQQPISKNFGPYSQGSGPVLHSPAMDPRVGGMYGNSGPPPMSGHGHVMENEPPAFFNGMPMQRPTQGVPPQFGQQMPPFSQQVHVSGPNDFMPPHPSQFGMPPFGAPMHPNMFPMNPVEMLMHRGPGGPLPPPRPMPGMAGPNHFVPNNFGHPMNNMPHPAPTFTFISATTSDTTGWDSSYSLGCYPYIGDNPGTNDPISVVQFGSTIEALFFPNGTWLTTIESGADTSVDYVSPKFYAIVASTNNWNWILAEASAKAGSTGSVGPWRNMRIGTTLEARTQDPSALGSDLLLTAGAIAPSTNAYGDGYFFTFSQSGTAGSVFRVTGNKQPDQNLTATEPLVSLTLVQSVDMRGISLSSNAVPVTAAFAAVILDKGPGGTISIYTIDPRTTTFSMVQSTVSGTWSGSGLVDPTAATATKSGGLNVALIGGIAAGAVVLIVIICVLIWRARSKKAMQLGIVKQQELDAIDRNNKDKMIKLLNLENQSTSGLGYNEIEHQRSNNGSSTTLTDPAANIAPRKSSDTDNHAHQYPEHRQSSKSQRPSRHASVRSTRSVGQISLYTSASSIYLVDSPSALPPTPMVPPAYANSSFENHRHIQRHYTGTSATRTSTSSSKKGSTYKVAVPDDYDDRQPLHRRNTDEFTLNQQSSYTAGSTGSTTSFNLSSSGEGGSQVLQDQPERARQPKSSPSSSNNKTSRNKAPSSSSLPSSPTSQRYPSDAPNPLYPSSDANNNQSPSSGKQRRTKDAPSYPRSKTDPSIKTTRASPTEGISKRTDHQYGSKYKESSASSRHRQQHSHQTPITPTTPISGSTAFSPTNSAFPPSPTASPTTPKPSSSDRDSRFTEAFPMPPRVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MR91</accession>
    <name>A0A9P6MR91_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein disulfide-isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PDI1_1</name>
        <name evidence="3" type="ORF">BGZ80_002044</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001495">
        <property type="protein sequence ID" value="KAG0009795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MR91"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034976">
        <property type="term" value="P:response to endoplasmic reticulum stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02961">
        <property type="entry name" value="PDI_a_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45815">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE A6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45815:SF3">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE A6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00421">
        <property type="entry name" value="THIOREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040184583" evidence="1">
        <location>
            <begin position="24"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="8"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0009795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="104" mass="11148" checksum="9F00C9C1D40B40FF" modified="2023-09-13" version="1" fragment="single">MRLSAAVALVGLAATSMFAGVRAESDVLELGVKNFAETVKAKELILVEFFAPWCGHCKALAPEYEIAATQLKEQGIPIAKVDCTVETDLCQEQGVSGYPTLKVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MR94</accession>
    <name>A0A9P6MR94_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001429</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001323">
        <property type="protein sequence ID" value="KAG0010509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MR94"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="252"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="327"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="623"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="676"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="746"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="953"/>
            <end position="1035"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="30"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="124"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="255"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="272"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="290"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="330"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="624"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="676"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="784"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="797"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="867"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="970"/>
            <end position="986"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="990"/>
            <end position="1000"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0010509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1058" mass="115210" checksum="A9DF0AA7CF94B4C7" modified="2023-09-13" version="1">MPAPQYSSVDPDRTVKSQTSLVDYPKKDVQSQQQHHPHQRGQQAQQVQPQSQPQTQQTQQQQQQQQQHQQTKFLPASAPNQTSVMSTTQEQFSFPTLKRNGVSFDQEKPLPSHPHQHTHHQQHQQHQYQHQQQQQQQQQQQQQQQQQQQQPQNSEVQPQPSQQKHQRRRSFMPTALMTSNLAKFVSGNHASPTSSIIPRSPRSPTVSSPVTTEKKVEEPSQVENTPLTMDQFKWSILCCCYEVKGRVARKRSESKQAASCQNPDTSVAPPALQQTSAPSTLRKSEKNKASRLNGSSTAQAAVDASSNDARIALKSLLLVMTLPTEEMGQRTGQRDASNASYAQDSGKSGYYHGPPSQMHNPSLLSLMGGGAAGTNAASADTRSINQMSQYSSSFQSLAPSVLSTTAALPPLHPSAAATTQQQHPQRVRSRRSQSRILLAQATDAVLHPLTMEELVRLLAYTLSVAPEQWIPWHLYDFFIRPQGQKYGDLVGLLPTHTQKILRTILETFDALVDYAVLMAIAQQQQQQQQLQQQLQLQHKPSTKTKMAASTAAAVVAALSGGNSNGTSLGEIAIGALGSSSTSGNGLRQQISQAHLRSKSDVTVVNNPGIETSIANLVAALTAPDSPSRSTFSTLSKSGDGGEAQDEVAIRARKRRAILDCLASLVFRSRKDATANLYGSESSRQNLDPSTAADDKSKNKRRSSGTAAAVAGPSPATIAMRLQASEKEQEAGLRAFENLVNAFEEDYRPQKSVQSSQRLNKEEDRHPQKNVQSSPRLNKVEPLAITTTIDGSLTNRASSPSVSLPSSPVNGSNSSFGVTLAPRQAQSLPNKDDSPDTKLATVRSPPPQKPVPAGSLIKSDPINGAIDNNNTTTITTTTTNTNNINNQEITKPHSGPARLRPRSDPAMSRPKTFYPSNNRHLSRVPTVLSATWSAWKDHVLVLEEEECVIGDVSDAESQGAGGKNGSLSKGSHVEEQGHGRQKDDYHNDTINNNNNNNNNNHNHNHNSNGHRHLDNYYTPSTTAGLPPPVSRKKSRAFGDLQQIAAALESGNPNLGGGNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRI9</accession>
    <name>A0A9P6MRI9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PRP1 splicing factor N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_001211</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001272">
        <property type="protein sequence ID" value="KAG0010753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRI9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000244">
        <property type="term" value="P:spliceosomal tri-snRNP complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000384">
        <property type="entry name" value="Probable pre-mRNA splicing factor prp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003107">
        <property type="entry name" value="HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010491">
        <property type="entry name" value="PRP1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045075">
        <property type="entry name" value="Syf1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11246">
        <property type="entry name" value="PRE-MRNA SPLICING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11246:SF1">
        <property type="entry name" value="PRE-MRNA-PROCESSING FACTOR 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06424">
        <property type="entry name" value="PRP1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13428">
        <property type="entry name" value="TPR_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00386">
        <property type="entry name" value="HAT"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PRP1 splicing factor N-terminal" evidence="5">
        <location>
            <begin position="13"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="45"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="60"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="586"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF06424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0010753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="586" mass="65356" checksum="1BFAFE7BA5B49E6E" modified="2023-09-13" version="1" fragment="single">MFGATKDFLGKPAPPGYIAGLGRGATGFTTRSDIGPAREGPTEADIAKLQEQAKRKAAEDGDDDDERYQDPDNETGLFNTAPYEADDEEADQIYDSIDAKLDERRKARREAREKEMKEQLNKERPKIQDQFADLKRGLNTVTAEEWENLPEVGNIAGKNRKKASLREKFAPAPDSLLPRAQEEMATTLDMQPNGLATPAPGTMTNFREIGEANKQVLGMRLDRMADSASGKTTIDPKGYLTGLNSVVIKSEAEIGDLKKARDLLKSVITTNPKHAPGWIAAARLEEHAGKLADARQIIDKGCTECPKSEDIWLEAARLNNTENAKKILANAVKQIPQSVKIWLHAAQLETTPKAKKTVIRRALDFVPNSVRLWKTAVELEDDPNNARILLARAVELVPLSVELWIALARLETYENAQKVLNQARSKIPTSHEIWITAFCLQEANNKDVEKLVANAIKKLSVIESALSRDQWIEEAEKCEKNGFINTCQEIIRNTIGMGIEEADLKSTWMEDAENAIAHQSYGTARAIYAHALRTFPSKKSIWRRAALLEKSHGTKESLEELLLRAVKYCPQAEFLWLMGAKEKWIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRJ2</accession>
    <name>A0A9P6MRJ2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_001424</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001321">
        <property type="protein sequence ID" value="KAG0010514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRJ2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="100"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="88"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0010514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="122" mass="12684" checksum="F6D707CC7817BD28" modified="2023-09-13" version="1">MISLDAQWDFSLTRHSPGTNLNFTFDDFNNNLVNITKEMSGALKPWVESRANAIAAELGFTIPAGTADRVTPPPRDSGKGKGKGKGGSNSSNGDGNGNSAASLSVSGFAFIAMLASCLMMLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSA3</accession>
    <name>A0A9P6MSA3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Transcriptional repressor general negative regulator of transcription subunit 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">NOT4_1</name>
        <name evidence="15" type="ORF">BGZ80_000878</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001196">
        <property type="protein sequence ID" value="KAG0011172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1923159at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030014">
        <property type="term" value="C:CCR4-NOT complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16618">
        <property type="entry name" value="mRING-HC-C4C4_CNOT4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12438">
        <property type="entry name" value="RRM_CNOT4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000006">
        <property type="entry name" value="CCR4-NOT transcription complex subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034261">
        <property type="entry name" value="CNOT4_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039780">
        <property type="entry name" value="Mot2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039515">
        <property type="entry name" value="NOT4_mRING-HC-C4C4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003954">
        <property type="entry name" value="RRM_euk-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12603">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12603:SF0">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14570">
        <property type="entry name" value="zf-RING_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00361">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 9" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="12">
        <location>
            <begin position="10"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="13">
        <location>
            <begin position="105"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="14">
        <location>
            <begin position="192"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="9">
        <location>
            <begin position="192"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="247"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="466"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="606"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="748"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="915"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1075"/>
            <end position="1119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1195"/>
            <end position="1250"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="71"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="257"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="276"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="297"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="326"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="766"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="813"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="831"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="916"/>
            <end position="943"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="959"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1078"/>
            <end position="1088"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="1097"/>
            <end position="1107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1109"/>
            <end position="1119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1221"/>
            <end position="1249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0011172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1286" mass="141164" checksum="19FE16BA12244443" modified="2023-09-13" version="1">MYSEEEDFDCPLCMEELDISDRNFRPCPCGYQICRFCWHHIKEDLNGRCPACRRVYSEETVEFTPISADELAMIKNEKKAKEREKKEIEAMNRKHLANMRVVQKSLVYVIGLPPKLANDEHTLRQHEYFGQYGKISKVVINRRNAPIPAAGSSSGVPSVGVYITYARKEDAAKAIAAIDGSIWDGKILRASYGTTKYCTYYLRGMNCQNPNCMYLHEPGEDADSYTKEDLAVGKHHLQEHIVPYDPSIHKPAVLGRPTLPTQLSSSSLTPRPKHATVTSYHANTSSLSDWPAPGEKSNSEDKDRDKDKDDEGSALPATASWAKIGSNPSTPTLMNSRPLSRRTATEPPPLHAKGSTSSIITGVVVNNGKQKDSTFVDSPALDYSPTPAEALAIEAAAKQQMVQEQRLLQEQQRKILKKQQKQQEETDQQAELLSQKLKKQKQLEQERDQQELQKLKQLQETEQRLQQIQKEREQQHTDQKEKEVRDKKEKEAQEAREKKEIEEKRQKAEELERKEIGLRDLEERRRKQMDSMFVTTPTLSLGSFSFNPDASLATQPSVFGNGGGLIPLGSETPGAFGLDSFSAFSNLPVTPGHYTGSFNPFSLDDEPLMRHPAAPPSRSFLDDTDFDPITGRSRQVGPPIPGKPRQTSRFGFATDSQYGDSFSNDRYSTPQAMQDGFRALFPNVNVSFSNLNGSLSAQQQQQFQQQQQQQQQYPNSPLFHRQESMQTSGWETSDKQDMQMLQRNMSQLNMDPMPTTPSSRMAEYHQQLQMQQHSQRSGPPGITRNTPTPSTVKSPPPGLESIARSDISNWTGLQLQQRQQQQQQQQQQQQTSRINGWSNENGMSYMNNAGSVNQGNNQDVFGAFLKAAAASPQGQSVNLSSGNQGNHGTMAFQDPAIMSARISAASKASLVEALQNPPSGSNLTGYRMSPSQDSLRSLGNDTMSGRAGEVDRTSDAQLQQRQQSTRQSTPESPSSLQNFPLGSKRKEIKSVKGVLNSGMNAPLNGSSRSRPPSTPGSPLVEPRVQLFGQQQQQSASFGAGEVNMTGMTSATARSAKVKSDLLMGLNSPSRFSAAAMKDSNEAGHDQDGSTKTNGLYGSTGGQHGMNGYGQPSASANGSSGTIVSGPPPGLGMPTGSGNNSPYLMSSLLGHNQDSGLNRSYLSNNKSLDVASMMNALDFFGPGQASSLMMSPSWSTANGSSVNGGQHMGGYDGQGSSDIHRNSNGSSNGVKGNGNDSSNTNDTNSTTATARSVEDLELQVINAKMETQMLENQLNAVIKRNRRKLYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSC2</accession>
    <name>A0A9P6MSC2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_000843</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001186">
        <property type="protein sequence ID" value="KAG0011221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSC2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="82"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="428"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="446"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0011221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="480" mass="54039" checksum="50DFE30D93870095" modified="2023-09-13" version="1">MTPSSGRSVETEMPSLAYSDGNSTSSQVMGNNCPDVRNLPSPSSQETDNAESNNGDYFLTSVLNMIAPPVIPPPTIFDYSEFTNRERIARGGNGEIRRAFWPQRQTVVILKSLIENMRFTETNYDLSIDQPCIIQVEVMNQCRNHDNIVQFYGVAIRNSGDERNGERFMVMQYYEQGDLVKLIESPQPEPLSLNDKMYLAMDIAMGLDHLFKCGFHHGDLHPKNILIDTRRDCTPQQGRYQAKLTDFGLRRIRNNPNDYSSQQFGGVWTFMAPERMKPKNRPRYDVRCDIFALGVLYWYILAGRYPFKDPSTFSPGAREGRPDGTPNWYYNVYTQAWSEDPAARQQTLEEIVQVFRYNLGIRTPPTQYLDPSHAYGQYPATSFGHGGSTFSSYITSENQAHHYSGSSGGGSTIRGSPMLTPAAMLTPMSLNGRLSPHPPSPLFANSTASTSSSTRSTHPNHPRNRRDNLPGGMPVSVRRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSJ5</accession>
    <name>A0A9P6MSJ5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">40S ribosomal protein S6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">RPS6_1</name>
        <name evidence="10" type="ORF">BGZ80_000340</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eS6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001069">
        <property type="protein sequence ID" value="KAG0011907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSJ5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.2650">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00512">
        <property type="entry name" value="Ribosomal_eS6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001377">
        <property type="entry name" value="Ribosomal_eS6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020924">
        <property type="entry name" value="Ribosomal_eS6_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018282">
        <property type="entry name" value="Ribosomal_eS6_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11502">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01092">
        <property type="entry name" value="Ribosomal_S6e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01405">
        <property type="entry name" value="Ribosomal_S6e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00578">
        <property type="entry name" value="RIBOSOMAL_S6E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 10" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="FAD-binding" evidence="9">
        <location>
            <begin position="5"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="9">
        <location>
            <begin position="369"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="282"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="719"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="294"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0011907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="762" mass="84817" checksum="0E7F3283F7167552" modified="2023-09-13" version="1">MAPRLKVLIAGASFGGVTLAILLERAGIAYELFEASPSVSALGGAVVLGPTVMPLLEQLGLLEKVQNISKKLKTMHLVEENMNRIGEIDLTRHKQQTGYDSLVTTRSDLLSLLVSHIPEKKIYFSKRIVAFMANKEFVVIRCADDESYKGEILVGADGAFSKIRELLYHQLAKKGILPRSDAAAMAIDTAVALATATSPTGQFTPDQQIEAAEGELLGGGHVSLVGVTRPMNSNSFPILRETDSRSNTVINDQSQHTWSYFTVPGNRICWSVNLQLDEATLREQRARSPSVVPVNPPDRTPSPTPSTTSFSTISATSTFDPNHADLGWEPEITSVSPLGKLLSAECRTFQAPMLGGKTFGDLIDATPKEQVARALTEQTLFETWHHGRAVLIGDACHRMLSNPAHHGITNAMLDAVVLANLIRDLPSASPEHLVEIYKDYRADRYPHAKAQMQINDKVYHLMSGHVSWTESFMRKFAVRYMSKINQHFCDDKILSDRPQASFLHQVENRGSVHALPQKPHKVFALNIANPATGCQKTIDFDDERKTRIFYDKRISAEVAADSLGDEFKGYVFRITGGNDKQGFPMKQGVLLPSRVRLLLSKGHSCYRPRRTGERKRKSVRGCIVGSDMSVLSVSIVKQGEQDLPGLTDTNVPKRLGPKRANNIRKFFNLTKDDDVRKFVIRREVQPKNAEKKPYTKAPKIQRLVTPVVLQRKRHILALKKRRAENAKEAEAEYKALLAKRVKEAAEKRHEVKKRRASSLHKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSL1</accession>
    <name>A0A9P6MSL1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_000186</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001031">
        <property type="protein sequence ID" value="KAG0012137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSL1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0012137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="214" mass="24712" checksum="D51BEEC118B464B5" modified="2023-09-13" version="1">MTISKFLPKGFGYIKLPKLRSLRLVDICKNVNDSMSGACLDMAVSLAVLVNRNPHIIHLEASFVNYEISNRFWKVLATTWVAPVSLSLERSKPLEAKETNLLIKRKRGAKELTLAQKRSRKMEEQEANEKEKNKRVEEKEKEKEEEEEEEEEEKEMEELDELCFWTACAPFKELSLNFPDIPSFGSFGEQTLERVDSPSYRSMPKMTNAKASFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSR8</accession>
    <name>A0A9P6MSR8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Mediator of RNA polymerase II transcription subunit 7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">MED7</name>
        <name evidence="9" type="ORF">BGZ80_000201</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the Mediator complex subunit 7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001034">
        <property type="protein sequence ID" value="KAG0012109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSR8"/>
    <dbReference type="OrthoDB" id="10253553at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070847">
        <property type="term" value="C:core mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1520">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037212">
        <property type="entry name" value="Med7/Med21-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009244">
        <property type="entry name" value="Mediatior_Med7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044888">
        <property type="entry name" value="Mediatior_Med7_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21428">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21428:SF11">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05983">
        <property type="entry name" value="Med7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140718">
        <property type="entry name" value="Mediator hinge subcomplex-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0010">Activator</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 7" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="196"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="211"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="249"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0012109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="286" mass="31813" checksum="07001DB15EF89E81" modified="2023-09-13" version="1">MEEASAQQQGAAFPAPPYYFQRYTQENINLLEKANADPENAEITKSLEALPFPILALEPPPPVKKGAYWMFGRAWPVQDSLATLEEQGIEQLYPKGSIDRVKELKKLNHSAVFNFLELVHTLSTSPGEFATKVDQIRVIFINMHHIINEYRPHQARETLKLMMEDQLNRKKNETAALRKTCADLRKQLATLQALKQERLQPPGLDNDVEMSAPASSQSHISSSTTAISTTTASSSTASGVGTKPPRRLSGSEDKRKSIVDSTPLDPIAIKNAETLARMMDLCDDIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSY0</accession>
    <name>A0A9P6MSY0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_000670</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001143">
        <property type="protein sequence ID" value="KAG0011465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSY0"/>
    <dbReference type="OrthoDB" id="58379at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38696">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38696:SF1">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0011465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="274" mass="30359" checksum="8D8FC4F3866D9550" modified="2023-09-13" version="1">MAHPKLDPTLPTYGSLSPIQTSSIRICTISLLDKNKIRLIGTPPPLAPLLRSAIITCWGTISKESNYAGAHEFKLSGAPFRGQGPDLVRSRRLILGLLYTMARAGWDLVQASDVSRRRQDKDSLFFEYAEPIGGPSSSSGMRSLTGEIGPEGLREVELFAVTFNRTDRIRVISQQSSEAALRMMELIKQAVASQWKYGIQAERDYCGSLEIKLQGNPFGARGDQSVYARMMQAQMIANFRAEGFKLYTSIGLGSGEDGRDVESWILRRVNASWH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MT07</accession>
    <name>A0A9P6MT07_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_000332</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001067">
        <property type="protein sequence ID" value="KAG0011916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MT07"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047134">
        <property type="entry name" value="RNF4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027370">
        <property type="entry name" value="Znf-RING_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23041:SF78">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RNF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23041">
        <property type="entry name" value="RING FINGER DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13445">
        <property type="entry name" value="zf-RING_UBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="5">
        <location>
            <begin position="301"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="119"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="261"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="347"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="125"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="145"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="347"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0011916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="416" mass="46306" checksum="5BBBACCF50031138" modified="2023-09-13" version="1">MNSTTNGVNLLGNTTQSSGHGASSSNSVHLIDLTVPTPPRIIHPRVLPSQSVEIIEIDSEDEEPRRDYTHQDGEGDEEVQFLHETPAPMSSWESRGPLQPSIDNLLLRYFSEQNVDLFASPSRTQAERGRQSPDRASQSRDARLNLNNNAGMVTGETTSGTDPRRPLRDRVLSSGIWNTHGTSTGSTDASVAAQRRLSNQLEEAADAASYLRHYLTLFRPSHDYEHHPYRQRHRRPRRGWLFGEDPIDYIPFTDDFFSRRGSPEAQASTMNAEQDEPEHKPLVPARPGHTKTLSQDVILACPVCKNELGYGKENTKLWVVIGCGHVICGDCIESVFLSKVMKKKPASKKSKNKGKAKWTAPVDTEEDSGVQGEGETNEESKAMNTEVGFKMVMKQSGHCPSCSRSIRKTSIQQLYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MT57</accession>
    <name>A0A9P6MT57_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">von willebrand domain containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_011715</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000979">
        <property type="protein sequence ID" value="KAG0012461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MT57"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042855">
        <property type="entry name" value="V_SNARE_CC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013694">
        <property type="entry name" value="VIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45737">
        <property type="entry name" value="VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45737:SF6">
        <property type="entry name" value="VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00957">
        <property type="entry name" value="Synaptobrevin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08487">
        <property type="entry name" value="VIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13768">
        <property type="entry name" value="VWA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00609">
        <property type="entry name" value="VIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50892">
        <property type="entry name" value="V_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51468">
        <property type="entry name" value="VIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VIT" evidence="5">
        <location>
            <begin position="10"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="3">
        <location>
            <begin position="288"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="domain" description="V-SNARE coiled-coil homology" evidence="4">
        <location>
            <begin position="834"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="524"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="749"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="898"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="907"/>
            <end position="922"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0012461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1030" mass="112015" checksum="12C3619818F5408A" modified="2023-09-13" version="1">MTTLPLICGLFYIQPNTRTPRQFLPLVDIEAHSTILETTSRTKLTQTYFNPSEVYNIPELQYTFPLYDGVSVVGFTCRIGDRTIVGQVKEKEKAKKVFKDAVARGEKAALLEQLPEASDVFTTTVGNVPAGATVVVEITYMGELKHDAEVDGIRFTIPTKIMPRYGNYPVELAKGKAKHADGRNIRVTIDVVMAEKSFIKQIQSPSHPIAVSLGINSFAPKADPVMYKASAVLNLESAGLEKDFIIIVAAKDAGIPTAILETHPTIPNQRALMATLVPRFSLPPEKPEVVFICDRSGSMSGSRIQLVKSALKVFLKSIPVGAKFNICSFGSSYSFLWKKSQTYSQSTLEEAINHINTIEANMGGTEMFQPIKATFDQRYKDIPLEVMLLTDGEIWDQERLFAYLNAQVIENKTAARVFTLGIGNGVSHALIEGVAKAGNGFSQSVGEGEKMESKVVRMLKGALTPHVVDYTLEVKYSDGDRMTDVGEDDYEIVEKVTDSLKVNLDLAEKKPASPTVQKPISLFDTTVDPDEDMPVPNDESGESRYSHLPPVAPPKLLQAPHIIPPLYAFNRTCVYLLMGPESSHLKPKSVVLRGTSRHGPLELEIPIQILDTPGETIHQLAARKAIAELEQGRGWITQAVDASGVLLKDKHESQFSDMVEREAVRLGVQFQVQGKWSSFVAVENQQENEKAKEKELLSVTNAAVPPPSYTMTISSASAAPSMAPQAFGGAVPTSGFAAPTFGSATPTSISTTSGFGSPHRRASSGYALPSAPGSACSAPPPPPPAPMAMAMGMSYSSPPPPPPPPMASAIYSSYSEDEELNADEDKEEGNLQMEQMMGVLKSNAEQLNQAGSIQRILERGEKLESLSSKSDDLSISSMAFNSSAKKSKRSSGFGSLFSKPSISSSRNKSEASESKKTSEIKKASSKPALSGSKLEILVELQTFEGCWEWEEQLFSCINILLAQAEKMAKDNGWDQKVVATALAIAYFEKKLAKEKDTWELVTDKAKGWLEGQIGQDQADAALEKAEELIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTT1</accession>
    <name>A0A9P6MTT1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tyrosinase</fullName>
            <ecNumber evidence="2">1.14.18.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_000179</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>2 L-dopa + O2 = 2 L-dopaquinone + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:34287"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:57504"/>
            <dbReference type="ChEBI" id="CHEBI:57924"/>
            <dbReference type="EC" id="1.14.18.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-tyrosine + O2 = L-dopaquinone + H2O</text>
            <dbReference type="Rhea" id="RHEA:18117"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:57924"/>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
            <dbReference type="EC" id="1.14.18.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the tyrosinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.18.1" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010001030">
        <property type="protein sequence ID" value="KAG0012142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTT1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004503">
        <property type="term" value="F:tyrosinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042438">
        <property type="term" value="P:melanin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050316">
        <property type="entry name" value="Tyrosinase/Hemocyanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002227">
        <property type="entry name" value="Tyrosinase_Cu-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474:SF76">
        <property type="entry name" value="SHKT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474">
        <property type="entry name" value="TYROSINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00264">
        <property type="entry name" value="Tyrosinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00092">
        <property type="entry name" value="TYROSINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00498">
        <property type="entry name" value="TYROSINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0186">Copper</keyword>
    <keyword evidence="5" id="KW-0470">Melanin biosynthesis</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="9">
        <location>
            <begin position="289"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="481"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0012142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="503" mass="56341" checksum="52CD88A250648F42" modified="2023-09-13" version="1">MDKVVTRKNIRDLTPEEKDNLIRAFAAIQQLPPDDPNSFFVIAGYHGQPFRGAGYANPSWWGGYCNHGNSQVPGVAMPYWDETEDSSLKEGIPSIFLERTYTFSDDTSRTIPNPLFSYKFQAKITDRLNANDKSTNYTKPVGYETVRYPFSGLVGTISDTEDTLIHNKKLLEKGEGETNRMLNENIMTWLNFSHFKNSDGKMMPAGVKDKFKDCLDAPNYTVFSNNTSAQRWNDDRLSEPGYQSITSIESPHNSIHLAVGGFNVPGHDNYDQYAGANGDMGENDTASFDPIFFFHHCFIDLMFWRWQVKHDQRDSLEIIEGYPGTNSVDSQGPTPGVAGGIWLTLDSPLEPFKDLRDPTRTITSREVVNIANLGYTYDRAEPPLTAPPNALPAPILTVSNINRATLGGSFVVSAWANLENGQKVLVGTEAVLSRWHVAGCRNCQNHLEVRAHFPMEGWNKGEVEKMRFEVVLNTRMLDRGLRNADGPQQGAQNPMIELSTDNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUI8</accession>
    <name>A0A9P6MUI8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_010689</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000772">
        <property type="protein sequence ID" value="KAG0014047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="196165at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051286">
        <property type="term" value="C:cell tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015630">
        <property type="term" value="C:microtubule cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030950">
        <property type="term" value="P:establishment or maintenance of actin cytoskeleton polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008104">
        <property type="term" value="P:intracellular protein localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17043">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053039">
        <property type="entry name" value="Polarity_Bud-Selection_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000159">
        <property type="entry name" value="RA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47775">
        <property type="entry name" value="BUD SITE SELECTION PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47775:SF1">
        <property type="entry name" value="BUD SITE SELECTION PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00788">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50200">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="166"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-associating" evidence="5">
        <location>
            <begin position="646"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="135"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="281"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="402"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="426"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="607"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="752"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="793"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1014"/>
            <end position="1202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1214"/>
            <end position="1244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1290"/>
            <end position="1345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1377"/>
            <end position="1419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1431"/>
            <end position="1561"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1627"/>
            <end position="1676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="18"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="52"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="72"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="281"/>
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        </location>
    </feature>
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        <location>
            <begin position="314"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="337"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="369"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="488"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="516"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="528"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="553"/>
            <end position="573"/>
        </location>
    </feature>
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        <location>
            <begin position="574"/>
            <end position="584"/>
        </location>
    </feature>
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        <location>
            <begin position="752"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="796"/>
            <end position="816"/>
        </location>
    </feature>
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        <location>
            <begin position="1019"/>
            <end position="1031"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1045"/>
            <end position="1059"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1101"/>
            <end position="1120"/>
        </location>
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        <location>
            <begin position="1172"/>
            <end position="1189"/>
        </location>
    </feature>
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        <location>
            <begin position="1231"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1305"/>
            <end position="1315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1324"/>
            <end position="1338"/>
        </location>
    </feature>
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        <location>
            <begin position="1388"/>
            <end position="1412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1443"/>
            <end position="1452"/>
        </location>
    </feature>
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        <location>
            <begin position="1471"/>
            <end position="1487"/>
        </location>
    </feature>
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        <location>
            <begin position="1496"/>
            <end position="1513"/>
        </location>
    </feature>
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        <location>
            <begin position="1522"/>
            <end position="1561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1627"/>
            <end position="1642"/>
        </location>
    </feature>
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        <location>
            <begin position="1643"/>
            <end position="1676"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0014047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1732" mass="189314" checksum="96D77B1B31C374E7" modified="2023-09-13" version="1">MASVTGSSSRLGYGGVSGLASSLRSAAASNTTAASSGSQRQYQRNMDATVPDSDDSTEEDEEYTSYIQEQEQQLRRGDGHNNNKPSNGIAMNVRQMLREEEHNQGANNNHYHNQQDHDMDMDTNNQLLQARQNEIMEDDEDLDDEEDEDEDMEEGSETLSLTEEDIDFNLVYAFHTFVATQEGQASVVRNDSLMLLEDANVYWWLVRVLKTGVIGYIPAENIETPFERLARLNKYRNVGLSAPAPEWGTFDEPIRPLSPNALAARSTNRRSVIFNPEDEFFGASENEWDSDESSDEDDMGEYYDGHEDDDAEDSDRHGEDDRDHDNGRSGKSALQLEAERVEQEIMDELRQQEEQQQHQRRSRNQYGMEESDQDDYEEETITNRHRRPLLDDDDLLFSDEPRKISLTPSIAQDDDLLFSDEPRKISLTPSIARDDATSTKAQGPPGKVKKLRIAEDEPSNAVSLRSGSLAGQRGNDNAASSSQQSSGNREEEDRQQMQKRIQEEKEAKLAAILGETDQSGPGGASQTAKEDPEPVETVKKPGKFKSLFGVGKSSKDKEKERKEKERLEKERLKNSASKGPPSSINTTTTNNAKATYSAGATNEADNVAARARASSNGSVTSAGAIANSSSPLSPSSHVDNEDSQQEIITLRVYPGNVDFGASMYKTVVVSPTTTASEVANHAVVKFKLAPENVSTADFYLTVRGVDGDETVLQPTDRIMAIYQSLTAHLTTPLPPNHRLSISSVSSMMSVNSTSSHTSITSPLSPNSVRRIGSGRSDPHQRSIRFLLNKRIRRSASVSSVPGTPTTPTTPTTPTSSMHQQQDDFFWVKVICLAQELPQTMILIDGIRVALDKNDPKIQGQMASAKVEHWIPMASTSNARDVIFKMLDMMEIRSGVVNGVPEHVIAAKRDSVPNGIVTEYQLGLRLNSQTSNRARHGDELPLPPQIPLIRCFEDHHLAPVRRSPKADVASMPPNPDHVFYLRKAPKSVQAEKDFEAQKQQSSKKVPAPLQVQALRPSHANEPQRSPLSPTGVSSPRSLRSLRSNEDMNMTAEQNPNSTGRNPGAPGSPSQIGNDIRIPRRTDSNLMGPASPTRASPHDMSSGRPSPTMQQQHGMMQSSRTPTPDHIGGRARASSISQISGPGIRLGQAPSPAPSAMSNHTPEIDGSRSSTPERPARPERPERPERPDRPQRAISPSMTHGPSPLSLAAVMLQQDGNQSNTKNETVSRERRGSSATPLSIKKNATQGMDIQLDKGVIRSSRLMNSKQYRYSFIPVEGGEEVDISEIIEDILGEDDDGNANGDDGDTQRNVTATSASSGRDGLVATRAARSSSNSSNNRNNGDLSDRDRLELLTNSAHSGDTLMKLEKVLAGDRDISRNKNLASAVRNRSDTSPSQRQRDNASASKANTPPTSQRNPRRDSDVEIQVASVASLSTRSVSPLMAEHTASTTPSGSPRSLRPMSPYGVMAKPTLISNASNAGAGTGTGNKSSPLKDAGISSDASIDPNQSQDSSQRSYSPIPRRLQSPSPATNSPRSSSPTSRLAQLNGSNSLNSSTTSLNSATSNGGKEWLLSSDYNAGMQDLLTLVRAGRSASVSSTSNSPMLLRGPLIGKDGKIVMLPSTIKASLLNNSSGISRSRSPSLSQLQEHLDAHQDKQGQQQDKHLNNDDKSDSNDKSRSNDEQTRMMLMMLNELTLKDVQQECHPEVYECWKDVDADLDRVERELDELLVTVKTSMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MV93</accession>
    <name>A0A9P6MV93_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">UDENN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_010170</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DENND6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000680">
        <property type="protein sequence ID" value="KAG0014888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MV93"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055037">
        <property type="term" value="C:recycling endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024224">
        <property type="entry name" value="DENND6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037516">
        <property type="entry name" value="Tripartite_DENN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13677">
        <property type="entry name" value="LD41638P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13677:SF0">
        <property type="entry name" value="LD41638P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50211">
        <property type="entry name" value="DENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDENN" evidence="3">
        <location>
            <begin position="1"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="321"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="364"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="404"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="437"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="467"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0014888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="543" mass="60157" checksum="F8E873B1D461127E" modified="2023-09-13" version="1">MATWRPPTTEGLMELPFMGTLYQVQLAKPHQPQLLETSPFDIATYQPDTHILSSVPMDGGLYKHFQDLVPDLWLCWELMTLAEPIMLIGTSPEIPYCGDYRPYFTIQDTDFKSFCNKSSPPSSIILGVTNPFFAKSLEHWPHIIKIGKPMNRRPNNKLMNDGSIGKTTGSPRQGKPTSLDFVQYFATLTEKFLVPLNRYFATLVPNDISLSSTSQFPHIAPFKQQTFLKFLSKNPPAISFKTSTFKSNSEACQSFYKDFLKCGNFATWLRLRTIAAQNELRRRYLEILSLGDVAGWVKGRNEVEVVDLLVRMREELGSSGNKGDLFSLKPKPKTRPGLSREGSDPLVELGSAWSRDLTNGHRRYADERQYSGNGIGSGSGSGSDVESRTITPPLDPSIGGRQISLPSTPNGVNGSNGLTGPRTIPSRRLPEAGGIYSTASSFSSNSSRTATPSRSSSSSSLNAGWAENKDREEGGEPRESSPERQRQRYAPEASAIKATLKQKEQLRDQIRLLIEALPVDLRESLKANEAKKRAAAGASHEVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVE1</accession>
    <name>A0A9P6MVE1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_010906</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000810">
        <property type="protein sequence ID" value="KAG0013719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVE1"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040176">
        <property type="entry name" value="RNF121/RNF175"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13407:SF0">
        <property type="entry name" value="FI05221P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13407">
        <property type="entry name" value="RNF121 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="75"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="99"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="137"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="172"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="321"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="8">
        <location>
            <begin position="227"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0013719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="346" mass="39927" checksum="3B91835BAB8B1D1B" modified="2023-09-13" version="1">MEQEAQRLEHIIEEAHDGKIHLSDNQIHNLENQAKYFHEHAGHEETHSRMALIIIVSLIAFQFVLLWWKRHHYRSYQATTTIGLWLIPFLFAIQSGMNQFATVWAIFTILNSWIIYKATRKPLHHMTPKIVYKWFWVIYQISYIIGIIGYFMMFLTFMGFGVSEPKDGEEPASSGLISWGLTLLSYGIYFGILGRDFVEFCTESMASTLGYYTKEGFPRKHLRLGVCAICGIHVSNAISTIDAHGHLQPPVVLQPSPNGAPIEPSIKLNCGHEFHEECIRGWCLIGKKDMCPYCKEKVDLRAFKTNPWDTTQQLYLNLLDALRYMIVWQPVIMGLVQFGFYMTGLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVM2</accession>
    <name>A0A9P6MVM2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA pseudouridine(55) synthase</fullName>
            <ecNumber evidence="3">5.4.99.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_010467</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a uridine in mRNA = a pseudouridine in mRNA</text>
            <dbReference type="Rhea" id="RHEA:56644"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:14659"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the pseudouridine synthase TruB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.25" evidence="3"/>
    <dbReference type="EMBL" id="JAAAID010000730">
        <property type="protein sequence ID" value="KAG0014401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVM2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160148">
        <property type="term" value="F:tRNA pseudouridine(55) synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990481">
        <property type="term" value="P:mRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.10">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01080">
        <property type="entry name" value="TruB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002501">
        <property type="entry name" value="PsdUridine_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014780">
        <property type="entry name" value="tRNA_psdUridine_synth_TruB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13767:SF2">
        <property type="entry name" value="PSEUDOURIDYLATE SYNTHASE TRUB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13767">
        <property type="entry name" value="TRNA-PSEUDOURIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01509">
        <property type="entry name" value="TruB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Pseudouridine synthase II N-terminal" evidence="7">
        <location>
            <begin position="504"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="84"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="247"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="299"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="91"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="299"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="317"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0014401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="776" mass="85460" checksum="68F8CB7BCDAB14EA" modified="2023-09-13" version="1">MAVTTDTSKNLYLPKIIELVSAAVQALAQNSGATTPRPALTGLLPPLLPRFDKPPELAVLEPANKHEQSITKFDPKELLTTLCPDLGSDRTLPTESARLSSSQSNGGDGTLSSLAPPQVPLDLKSILRKPRSFQTARHQVHVHPRLGPMLQSMHLSHLQLQETQQQHYILQKHTYINLNNAATTPSKTSLGKSTNVHSRPLPTPPIIKHVRWSTHNEVLEIENIDDLILLGYYDDYDGDLGWDYRDESQEYSSSDEDEETEERGLSISDDKEVGQFGGLTLRTKNAPFRDTSPDLAYHQQLQPHSQSPPSTCSDYGFDTESDTSTIDEESEIAEDELIERFENHYDAFGSLSSIAESNQVFEATSDFGCVLKGKAPRLDRREILAEVAARKQNGMGAFARRTGPRRSAIAPRSFEFESSLFRVDTDSSASAATVATIRATTPPKSQSRPHLHLPLTGVFAVNKPTDLTSTTIIDLLQHVCKKNRAHPLVKRVLELDGSKRAKRGLVKIGHGGTLDPLARGVVVIGMGAGCKMLHNMTVSSSKVYIAEARLGFSSTTLDSTGSLVAEGPTDHVTRATLMQTLNAFKGEIKQTPPLYSALNMDGKRLYDYAREGLALPREIPSRKVQIHELELLSFPDDSIPPDPILEQYKFRGNSDTTITTTSPVQNFKTGFQPKRLTNSSVMDPSHVPIPTVPRGLVFHIRVHCSSGTYIRTLIADIAAHLGTVGHMTDLLRVEQSGFKLGGLATLEMEECEDVDRVDQAIQAGNRIQESMEDEHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVV1</accession>
    <name>A0A9P6MVV1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_010562</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000749">
        <property type="protein sequence ID" value="KAG0014232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051566">
        <property type="entry name" value="CNKSR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12844">
        <property type="entry name" value="CONNECTOR ENCHANCER OF KINASE SUPPRESSOR OF RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12844:SF42">
        <property type="entry name" value="CONNECTOR ENHANCER OF KSR PROTEIN CNK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="170"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="390"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="446"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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            <end position="598"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="613"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="654"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="707"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="789"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="914"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1045"/>
            <end position="1067"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1093"/>
            <end position="1117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1190"/>
            <end position="1210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1222"/>
            <end position="1252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1264"/>
            <end position="1292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1305"/>
            <end position="1352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1365"/>
            <end position="1399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1424"/>
            <end position="1499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1524"/>
            <end position="1584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1627"/>
            <end position="1660"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1710"/>
            <end position="1824"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="75"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="403"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="418"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="446"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="463"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="477"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="583"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="669"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="707"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="731"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="793"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="928"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1050"/>
            <end position="1066"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1100"/>
            <end position="1114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1235"/>
            <end position="1246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1271"/>
            <end position="1292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1305"/>
            <end position="1316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1333"/>
            <end position="1352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1365"/>
            <end position="1377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1424"/>
            <end position="1444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1526"/>
            <end position="1539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1540"/>
            <end position="1566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1648"/>
            <end position="1660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1716"/>
            <end position="1727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1760"/>
            <end position="1792"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1807"/>
            <end position="1824"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0014232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1824" mass="195257" checksum="14AA97C0DFCF5C15" modified="2023-09-13" version="1">MAYQSQKQQEQARQQQQMQVNAQYYDTLQPSASSSPSSWNARKDQQFCSSSPSTPPGYVNSDVLYSYQQQHNTDNKNNNPNNNNNPDESLRSSSHHNNNNTMNSHHKHHHKQSSKDEMLQLRHFTSNGSGGSSGSSTNRQGTPNSIPSIFRLQESLANGTATESTEPDDHIMLQDWLQKRSTALQMVWKRRWCVLRDNRLFYYRSNTDTKPLGVLHLADYSILSSGSEITRKSKYAFRLSSPDHQNQSHVFFSDTAQSLDNWTHALQIHINQAVAALLSLAEASDKLGRQLRENENTNQTAVGRGAHGAELSIIDKVLDRLQLEDPSPSETSSAVPSQQRVIVREPITLLQSYDENADTWSSVSSIHNTSSNNSSNLDYIFALNQQQSTQHLAKSSMDSMRESQQQNNNCGGNSNNNAVMSGSQSIHSVSSNNGYLAGPAFSEHLSVSSMSDGSRSARQSMESQGRSSLQQSRSGMASGNSPSMNPIRSNGQSGPSIDNNSSPAASTIDSPYSSPALKSQSHTIPNNAQGSICGGPVPPPASPMTFYRILENSKEAGSIGSSISISSLGSSGDASTAVDPTLDSGSSVAATESSHGCKQSGGNLFLDLVTGGKHRKDKERRAQNSSGSSQSGNGGSGGSSSLKLFSLSVCPHSGCTQPAKSCPLHSKKPRPESPMKPMEKEIKKIKKLWSGSDKNVSQGTLSVASSSIYSGSDRSSSPVQSIVSPKPRASKSMTSLSRENNEFEVNSNPMPQLSNPLLNILPAPSRRRSPSVSIVDDVLVAAQTRHQQHHHILQTQQKQIRTSDPIQQQSILQQQQQQQQQQQLQPTGTSQPQSKTPPSVLPAAPMQPLPLPPLHMTTAESSTIPQPRTGGSGTLSRKMGLLLGDDFGTFDKSKYPNSPLEGNVFVANHHRTMQKLQGKNARKNQPVNSGSSSGSTPSTNPLSAPSTPIQASFGIDQQRYQMLQQQQQLQASLQIGGVSRHIVAPDELALAIEQEAEDMRRQQAEAIECQRNRPTSMIGNAKIFQSLPINVGLLPLSETASDSGVSAGDSLSESIGQLSSTSSGQTQVEGERIISSQEQLTCGLTALTSAIQQPVERQRSPISGITSTTSSPRSNVTKYSYSSSVPLTDSELSAVAGDVANSSGINISVTTTTPTFEYPPQSPHSQGLYDQFHKQSRPSMNYRTLSFDEKEEEYPFRSLPPPKRRGSDKAAFQADLVNHEAYRTFSRQTGPPRRSSATATTGTGSAPWMPMTKDSFTILTELTERDDSSTSEASGGNARASSSASSPSMSSSPVIIRLSEQGGQNISPLINNNSPRTFAGSVPSNDVRRPGATPTTSSPSGSSQSTSTVSSTLCSIVGPDHVRHESVEAESNEEHHSGLALGGASSPAHHTPSVMSPISEDVPVSPIPLSNSSRLRSILSPLASATPINGSSPSRSPGSPSASSVMRMRSSEDSENGQQQEEEEQVASGSQGAQNDNEDDSKGMNVPSVVINSPHETLSRRRDATHRNIMMQMQAAQNFVFPAPRTSTSTTASADASSTNDQPPSSRTSIDYFSSTAVSSEASTPNGEEGDMSRSHPSSPGHTASALRAHMAALDLYPGLRKLSLFTAAVGNNPPPALIMGRRKGSAGSACARERKMSTVSSFSRMESDDDHDEEYDDDQQSVDLQHDEDWAGNLKSLKGKNGSYVPPMPDAIKHRPSLPFVVHSSSGALTMQLSTPPPSSPLPHLPPRTVHTPSNPLRVIADNSGTTYTSLLRPPPSPSSSSLTSTTTATTATAATATATTTAGAPYAPRTHSPLIPSEANPPAIPRRSPQRSAPSSPTLLKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MW78</accession>
    <name>A0A9P6MW78_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA-directed RNA polymerases I, II, and III subunit RPABC1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">RPB5</name>
        <name evidence="8" type="ORF">BGZ80_009531</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000580">
        <property type="protein sequence ID" value="KAG0015947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MW78"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006362">
        <property type="term" value="P:transcription elongation by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042797">
        <property type="term" value="P:tRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1340.10:FF:000001">
        <property type="entry name" value="DNA-directed RNA polymerases I, II, and III subunit RPABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.940.20:FF:000001">
        <property type="entry name" value="DNA-directed RNA polymerases I, II, and III subunit RPABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1340.10">
        <property type="entry name" value="RNA polymerase, Rpb5, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.940.20">
        <property type="entry name" value="RPB5-like RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00025">
        <property type="entry name" value="RNApol_Rpo5_RPB5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014381">
        <property type="entry name" value="Arch_Rpo5/euc_Rpb5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005571">
        <property type="entry name" value="RNA_pol_Rpb5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036710">
        <property type="entry name" value="RNA_pol_Rpb5_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000783">
        <property type="entry name" value="RNA_pol_subH/Rpb5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035913">
        <property type="entry name" value="RPB5-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10535">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10535:SF0">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01191">
        <property type="entry name" value="RNA_pol_Rpb5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03871">
        <property type="entry name" value="RNA_pol_Rpb5_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000747">
        <property type="entry name" value="RPB5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53036">
        <property type="entry name" value="Eukaryotic RPB5 N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55287">
        <property type="entry name" value="RPB5-like RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="RNA polymerase Rpb5 N-terminal" evidence="7">
        <location>
            <begin position="6"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase subunit H/Rpb5 C-terminal" evidence="6">
        <location>
            <begin position="135"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0015947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="208" mass="24048" checksum="3EA1F5EC82FA2AD9" modified="2023-09-13" version="1">MDNESREIVRLWRVYRTIHQLCNHRGYLISQAELDQDLESFRNTFAAHGKVDRNALMFMVQKKDDPADQMLVFFPDEASVGIKTIKKYCELMVAKGVGRGIVVYQDKITPSAAKVISEVSHSYHLESFQEADLLVNITEHTLVPQHIVLTPDEKDTLLKRYRLKETQLPRIQPSDPIARYYGLARGQVVKIMRPSETSGRYVSYRLCY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWG4</accession>
    <name>A0A9P6MWG4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Putative 5'-nucleotidase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_009370</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000554">
        <property type="protein sequence ID" value="KAG0016209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWG4"/>
    <dbReference type="OrthoDB" id="7722975at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009166">
        <property type="term" value="P:nucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000043">
        <property type="entry name" value="Ser/Thr protein phosphatase family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.780.10">
        <property type="entry name" value="5'-Nucleotidase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036907">
        <property type="entry name" value="5'-Nucleotdase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006179">
        <property type="entry name" value="5_nucleotidase/apyrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053828">
        <property type="entry name" value="Nucleosidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014485">
        <property type="entry name" value="Pesterase_C1039"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575">
        <property type="entry name" value="5'-NUCLEOTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575:SF22">
        <property type="entry name" value="ADL392WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21953">
        <property type="entry name" value="NadN_nucleosid_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017316">
        <property type="entry name" value="Pesterase_C1039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55816">
        <property type="entry name" value="5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040344425" description="Putative 5'-nucleotidase C-terminal domain-containing protein" evidence="1">
        <location>
            <begin position="16"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="domain" description="Putative 5'-nucleotidase C-terminal" evidence="2">
        <location>
            <begin position="370"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF21953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0016209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="574" mass="64305" checksum="A8A6123090514D39" modified="2023-09-13" version="1">MRLLALLPLMAVAVAHVEHLEPRSQPGVPQPTPVDLRPLEWGDLNIISTTDTHGWLAGHVKEGSYSADFGDFASFLAHMRQQANYRRKDLLVVDSGDLHDGNGLADATNVSGTVSNPIFEKINYDALAIGNHELYLPEIAVDTYKNFAPKWGKKYLTSNTFIKDAHTNKTVPIGKLYNKFRMKFGTRVMSYGFLYNFVGAANNTIIEPANVTVTLPWFQKSLKEDVDVYLIVGHVPVRWAEAVSVINAIRAVHPSKPILLFGGHLHIRDFKAYDGRAFGLSAGRFMETLGWMSVSGIHDRACRVEANCIGKNLTVSRRYLDTNVHTYKTHSLSHRKQRFDTWRGRQITKEITKARKALGVSTVLGCAPQDYFLNRYPYTDSRSLLNLVTKEILPFSIVDKTRPYPTVVFINSGCQRFDVFKGAFTVDDTYIVSPFHDDFEFATVPYKVAKNLLNGLNKAPFQKRAEVQASSTNVTLTPGYVTNDDYGLGGDDWPHSPIPYVATPNYVSTDLPTGLGDNDLVDVAWLSFFTNLMAPLFKKLDPAGNYTIQPYRVGITTYEMWPIFAKAKWANATC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWT7</accession>
    <name>A0A9P6MWT7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_009612</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000590">
        <property type="protein sequence ID" value="KAG0015835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWT7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0015835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="324" mass="36906" checksum="1E4F93A5F7E0DE3D" modified="2023-09-13" version="1">MSQEQAEAKRRDEEHKRMLQQSIDRMVILQRGIDVVLVQNYELHEYPIPRLFVILPEKIASKVIKDIEHSKESHESFSSSKEEDEDQERFIDTFKSLDPRNLLEDRFRLYFLCECGDHSSTEPDTSTSYAQTSAHPTINTKNKVHLAKHKGNQLSRPTQFLKQYGPYILGMLQILKFCLDAAKFVAPAVGIAQDISEDTLEAVNISINFLETKLGGDINLDPQDSDGIGDDIFKNLAALEGADLRQLETFLRNKDKDKILGNLYRTTTPEGHVKWVCLEHFKASYRENAMGSLLNTIEVNYGTYDKQLKKITLVLPSSIATKIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXE1</accession>
    <name>A0A9P6MXE1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">MEC1</name>
        <name evidence="19" type="ORF">BGZ80_009564</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PI3/PI4-kinase family. ATM subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="JAAAID010000585">
        <property type="protein sequence ID" value="KAG0015888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000077">
        <property type="term" value="P:DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00892">
        <property type="entry name" value="PIKKc_ATR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1010.10">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056802">
        <property type="entry name" value="ATR-like_M-HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050517">
        <property type="entry name" value="DDR_Repair_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003152">
        <property type="entry name" value="FATC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057564">
        <property type="entry name" value="HEAT_ATR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018936">
        <property type="entry name" value="PI3/4_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003151">
        <property type="entry name" value="PIK-rel_kinase_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014009">
        <property type="entry name" value="PIK_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012993">
        <property type="entry name" value="UME"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139">
        <property type="entry name" value="ATAXIA TELANGIECTASIA MUTATED ATM -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139:SF125">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE MEC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02259">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02260">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23593">
        <property type="entry name" value="HEAT_ATR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25030">
        <property type="entry name" value="M-HEAT_ATR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08064">
        <property type="entry name" value="UME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01343">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00802">
        <property type="entry name" value="UME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51189">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51190">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00916">
        <property type="entry name" value="PI3_4_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="14" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8 19" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FAT" evidence="17">
        <location>
            <begin position="1253"/>
            <end position="1870"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="16">
        <location>
            <begin position="1979"/>
            <end position="2282"/>
        </location>
    </feature>
    <feature type="domain" description="FATC" evidence="18">
        <location>
            <begin position="2341"/>
            <end position="2373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1205"/>
            <end position="1228"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="2289"/>
            <end position="2319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="1215"/>
            <end position="1224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAG0015888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="2373" mass="268364" checksum="5DCEAAFD58B09750" modified="2023-09-13" version="1">MKVAHLPKEAFPSRSPSRQLLSMLKKLAGNSTYISAASQVSRGIPPPLSIEALQSSVVLVQVWVKFTINSDSTEIEGDVNQLTGLIESIGKNYIIWALSPGMQARLSEDLKALLICLSSGPWFPDLSKPELWRDTESTMDIDEIAGDLQLVRGIRGITEGTENLVRLKYNTSILQYCKSFRSQKCKALKIMSTLPHCPQLEVWRRDVILRSLKDVGDDNTPGATQGISQGLKIAALEALAVLSTHSPDSRCTVESATSRLNLDDETEETKRTLAFCMGVVACGYSNSNRKIGPKYYYDALSQTFTPRWICDSCDGAIETVFCGQNSASKVLATLLEPKFLNAFRRLIPTCVDEGSKVGLLRGLYRVFCHLELVDEDLKAMDFGKLMLNHLCDENESIRRAAGDIAELLSKRAGLAIADDPLAQSNIDESLARINEAIARGFSGCPRYTAIAWPLHLCRRIMRHLPEDHPIYHSLLIKMIDQAFTDKEIASSGFVFDQLSMIAKDRKLSNYRLLRPQMRYICEKVIEMLEAEQDRWLDVLFYPWIRISPIKFLQQNLSELVSTMILYYNRALIEKVAVILNEKAGGLCIRQIDHILAAIYIQSEEEPFKSRIELLRSLIVQIDQDSGKEARSLDIVELTMLSTSGLLCCLSVELGHEEAVIRDKAQKTIKIVEELAWERVKQEQELAGAQGKDVERPTLAIFLRRHVLAIMSEVNNVIMDLTRVVTLRLKAKYLRSLVVLVSLLKPIQSSVLSQILAPVYIALDIQGLRIHALRTLNAIIQLVKSEQLDVMLAHIVQTLTKRYPNSNKKEQAIELGILEYLIIHEGKEALRTCLLDVGTLPDLTEFAEMNRILKAVKAEDGLEKQLRRLIQRSGNENAELAEQALLELREILLANDRAILDLATTKERQVEPVMRDLIQALLSGIGRFRGLDAPVPRRCVECIGIIGAIDPAKLSTMRLIPAPPTHTNFADLEEAKNFVCEMIEVQLVGKTRSIGDIRSESHWAFTLQTLLSFCGITKGVLNAASQTPFRSFPRQPAIKTAGDRWRAFPRHVQEVLELLIDAKYTKGESATQRIYPSPLYPHFESFKEWLTVWTMVLINKVTGRYTKEIFQACKHVVPYDTSTCLYMLPHLVLTVLLEGSSKDRSEIVNEMAAVLGKSRNWEQNGAEQNLGTSQQISGELNQLGPQTVFGLFDHITKWIQSRKSLSAKTSSHRSHTTSSTTSSTTPELSQATLRQYDAAIDAVQEQLTSISHDVIAMAAFRCKAYARSLLHYEQYIRDSRQQLGPNDPAIQSMYEKLQEIYANLEEPDGMEGISSLITSGTATQNLLQCESAGQWSEAQFYYEQGLQDDPGQFENHAGLYKCLENLGHYKMLLSCVQGDIQSYPDWEQQLTDWRIGSAWKVQNWKTLESALSRSVHSSFETGLGQLLLDLRDNRVSEFESHLQQVRCMLIPTLAAASMESYSRAYDHIVQLHMLHELEVAFRSWNPNVITGPSDLTGNSLGSQIALSFREGDTYVERVRLFQQTMDKRFELMAPSFRLREQVITLRRIVFYDIRRENLGSHEDQDFLDDSCGRLWLQSARAARKSGNSEVSYSAMLRAEKLKNRSAPIERAKYELLHNNDRQAIKTIDMALNQILTVPVPASTIASRLVVSSTVSSRLRNTSNSSHRATSVNTDLKRVQNHTLDMNSTGYIRAKAYLLRTQWMDQRSLVSPNDILEGYRQATVECDKWEKGYYMAGHHYLKQYENSRRYRSRPPFLPYLTNACRLFGKALTLGPKYLYQALPRLLTFWLDLASQAQAASNANISSSTGHTEFQNVNKLMENLAGFLPEYMIISRMCHKNADAFAVLQHIIVNVVLAFPDQAIWQMVPISRSIVLERKRVCNMILDSIHLKPQIGHAIVDQIKEALDLCDNLITLCMAGVPEKVEKLSLQKHFPKVYTQLRQNYKITVPCQKTLWPAIPETSSTMASHQPFKSNLPKINRFMDEVEVMSSLQRPRKITIVGSDGLQYTFLCKPKDDLRKDAKVTEFNTLVNMLLRKNREANRKNLYIRTYAVVPLNEECGLIEWVYNTTPFRHIMQKQYKMNNISLYSIAEIKRILDHEDHVRMFTRDLLPKFPTIFYQWFMDISQEPTAWFETRLRYTRTTAVMSMVGYIVGLGDRHGENLLFDFHNGDIVHVDFNCLFEQGKTFPKPERVPFRLTQNMVDAMGLSGYDGVYRLTCEQTLGIFRDNIESLVSVLEGFLHDPLVEWAKNKRRGQQIQLDPPVVAVPAAPGAMFDAFIDQGNGVAGGAPTAADEARARLRSKAEAKAKAEAAIAEADSQQNEKAQTIMSLIKRKLQGNESPNGYTLSVQGQVEELIHAATSAENLSKMYIGWSAYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXL9</accession>
    <name>A0A9P6MXL9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_008160</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PER33/POM33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000435">
        <property type="protein sequence ID" value="KAG0017558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXL9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071786">
        <property type="term" value="P:endoplasmic reticulum tubular network organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061024">
        <property type="term" value="P:membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051645">
        <property type="entry name" value="PER33/POM33_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005344">
        <property type="entry name" value="TMEM33/Pom33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12703">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12703:SF4">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03661">
        <property type="entry name" value="TMEM33_Pom33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="94"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0017558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="202" mass="22284" checksum="D8072AD6CB8E26E1" modified="2023-09-13" version="1">MPGAPSSLNDRLLALVKENVQYLLMAFFWWRSTPMLAPMIPYAIFAFFNSLNYARTNIIPAFFPAPPAGTTDPTYNQVVAISRKIQVWTEKNHAAAMAFVAYVEVVGVMGSLIFGAITFQSSFLSPIVYANFLRFRYFFSLHTRSAFALIRARLDNLIVPQGGNPSIPPFVAQAYTTVRGAITRFGQAAVQQPAAGAHARAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXQ2</accession>
    <name>A0A9P6MXQ2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Biotin holocarboxylase synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">BPL1_1</name>
        <name evidence="4" type="ORF">BGZ80_007911</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the biotin--protein ligase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000415">
        <property type="protein sequence ID" value="KAG0017789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXQ2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004077">
        <property type="term" value="F:biotin--[biotin carboxyl-carrier protein] ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16442">
        <property type="entry name" value="BPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03144">
        <property type="entry name" value="GATase1_ScBLP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019197">
        <property type="entry name" value="Biotin-prot_ligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004408">
        <property type="entry name" value="Biotin_CoA_COase_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00121">
        <property type="entry name" value="birA_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12835">
        <property type="entry name" value="BIOTIN PROTEIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12835:SF5">
        <property type="entry name" value="BIOTIN--PROTEIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03099">
        <property type="entry name" value="BPL_LplA_LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09825">
        <property type="entry name" value="BPL_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="3">
        <location>
            <begin position="393"/>
            <end position="606"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0017789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="691" mass="75785" checksum="B5542E7A0169067A" modified="2023-09-13" version="1">MNVVVYSGEGTSRISLAHTVRSLRALVGQHYDVMKIDAKGLLTEPWEESTALLVIPGGRDIPYTKDLNGAVNDKIRAYVEAGGRFWGVCAGAYFASDRIVFEVGTPLEVQGSRELKFFKGECRGVVYPGFVYDSEQGANAVEIQLNKGALAHGEKLGFERTRVYFNGGGYFVDAEKYPDTQVLAWYSDNNNDGVDRKAAMVACRVGQGFALLTGVHPEYDPAHLDAGNPEYGPSPNVVTRLLESDQERTLVLRSLITTLGLKLTHPDSEQGNAAAAEGGANPTLPLGAIQGIPDITPLYLASVHPSYTDDLMRSLKGLITTEGLIKEPNDTFQLIASPQHAIPVHTSTISETAEGEGEEKIIKNIVICADIDSTPTAATTPHFVMSDFFKHLQHVRQQDHRLKFGNSLLYGEVVTSTQTMLDKNFALCKSLPDGFVCNATIQVAGRGRGRNSWISPPGCTQFSMVLRHPVQARHASAAFVQYLVALAVVESVCALPGYEDVPLKLKWPNDIYAEAPLEEGEERQPGAPPKMVKVGGVLVNSNFSGNEFLLVIGCGVNTTNPNPTTSINHLIRYHNKVTGKNLALFTQETLLAHMLVKFEQMYDLFLHGDRTGFAQLEETYYKRWLHSNAFITLTTMTPHRKVRIQGITLDYGLLRTVAVDEQGKDIVGEEFRLQPDGNSFDMLKGLISTKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYK3</accession>
    <name>A0A9P6MYK3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Endonuclease V</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_008189</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000437">
        <property type="protein sequence ID" value="KAG0017535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYK3"/>
    <dbReference type="OrthoDB" id="20018at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016891">
        <property type="term" value="F:RNA endonuclease activity producing 5'-phosphomonoesters, hydrolytic mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003727">
        <property type="term" value="F:single-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06559">
        <property type="entry name" value="Endonuclease_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2170.10">
        <property type="entry name" value="archaeoglobus fulgidus dsm 4304 superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00801">
        <property type="entry name" value="Endonuclease_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007581">
        <property type="entry name" value="Endonuclease-V"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28511">
        <property type="entry name" value="ENDONUCLEASE V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28511:SF1">
        <property type="entry name" value="ENDONUCLEASE V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04493">
        <property type="entry name" value="Endonuclease_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0017535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="310" mass="33322" checksum="FBF8CE37A67ADEE1" modified="2023-09-13" version="1">MAMADNTNNVSSSSSSTSSTAGDSQYSIPTALQKTEWAKQQSILKTNLVLTDDHPDWSVVLKPGNTHQLESVEGLKYIGGVDISFIVGNNEDAIASLIVLSYPNLKASLQVVYENYAKVKLTLPYIAGYLAFREVGPLLGLIQTLRADRPELEPQLILVDGCGILHPRGFGLASHLGLVSNIPTIGCSKNYLVIDGDGPILGAHPTMLKNIFRDFVATNKDAHGLMLLKGEVTGKVYGAALSAATTKSEDGAQNPIFVSVGHKVSLETAVAIVRACSLHRVPEPIRQADLRSRTEIKKWVKLLGQPVQQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYU6</accession>
    <name>A0A9P6MYU6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Arm-like repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_007891</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000413">
        <property type="protein sequence ID" value="KAG0017815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYU6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056251">
        <property type="entry name" value="Arm_rpt_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23948">
        <property type="entry name" value="ARM_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arm-like repeat" evidence="2">
        <location>
            <begin position="172"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0017815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="282" mass="31212" checksum="29D6F35CF2B50576" modified="2023-09-13" version="1">MDNSQSRGGSIQQTGTSRPGGKSGDPQPPHLTVDYLISPTTVDAMDHSITLPPNQTIFAQSAPLTATRYALPESGKCLITVPQFAYCLSLIQPSLVPNDGLDEIEHRWSQHILDDKDEQERLKAMPVTLIKAFIQEAKDRYTVTEIVSMAAILEQDDFRKLFRIFDDLTNPMVDSQVKGLSYDQFSTPLEEYLCELQKSADAYLIYQVAYASQALMHITDNESVLRTAPQRAGKVVRRISGVVSAVKTPSIIDIVDGLNNIQFGPTGLENMAKPTNPRMSAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0A5</accession>
    <name>A0A9P6N0A5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Mur ligase central domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_006248</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the folylpolyglutamate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000308">
        <property type="protein sequence ID" value="KAG0019133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0A5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008841">
        <property type="term" value="F:dihydrofolate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004326">
        <property type="term" value="F:tetrahydrofolylpolyglutamate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="entry name" value="Mur ligase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="entry name" value="Mur-like, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001645">
        <property type="entry name" value="Folylpolyglutamate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018109">
        <property type="entry name" value="Folylpolyglutamate_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01499">
        <property type="entry name" value="folC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11136:SF0">
        <property type="entry name" value="DIHYDROFOLATE SYNTHETASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11136">
        <property type="entry name" value="FOLYLPOLYGLUTAMATE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="MurD-like peptide ligases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="MurD-like peptide ligases, peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01011">
        <property type="entry name" value="FOLYLPOLYGLU_SYNT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01012">
        <property type="entry name" value="FOLYLPOLYGLU_SYNT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur ligase central" evidence="7">
        <location>
            <begin position="41"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0019133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="468" mass="51025" checksum="81E2AC94C091D5AF" modified="2023-09-13" version="1" fragment="single">MDLGLERVTQLLEALAPTNVSSTAGSASHVAPHLAFPVIHVAGTNGKGSICAYLSSILHAAGFRVGRYNSPHLITPRDTIQINNQPISQADYEFATEIVKQKDQELNLKATSFELLTATAFYWFAYGRHQTGQERVDIAVIEVGVGGRLDATNIVPRPLVCVIASIGMDHGALLGNTIEEVASEKAGIIKPGVPVVIAPQSEGEKVYRTLEKKAVDVGLSSSMVIKVKAAQWIKTDEVSSSLLAALTPTVTSGHWAVLENGFQVPIPLLGDFQLENAATAITAINVLRGNVDSVESVSDGQWAQKITDDVIRKGIKDTIWPGRLQWIEDVSSPREVQGRILVDGAHNPAAAIALRSFVDENIASSPDPRPRVHWIMGFTRGKDIEEMFDILFSKRTNQLEGSHIQERQDTFSAVEFSPPEGMPWVSPIPAQEICERLRLQQERIHASQQKDMLVIRGFGSDLKAALEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0U9</accession>
    <name>A0A9P6N0U9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004853</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000243">
        <property type="protein sequence ID" value="KAG0020052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0U9"/>
    <dbReference type="OrthoDB" id="2445712at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0020052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="130" mass="14662" checksum="5D74F6BAEC91C7DD" modified="2023-09-13" version="1">MDHQSSNTSTESHTPDPFTDPNPPKDGARQTAAKAVALPLAAVGGAIAEATRKIGELEFKILTRSNRLHHRTQHNSKHHISTRLETLRSPPQPLRLTRKRPFKNFGDKEKLQICEIMMNQLVRLKGIKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N127</accession>
    <name>A0A9P6N127_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">High-affinity iron permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">FTR1_3</name>
        <name evidence="8" type="ORF">BGZ80_005286</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000261">
        <property type="protein sequence ID" value="KAG0019785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N127"/>
    <dbReference type="OrthoDB" id="4364at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033573">
        <property type="term" value="C:high-affinity iron permease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015093">
        <property type="term" value="F:ferrous iron transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004923">
        <property type="entry name" value="FTR1/Fip1/EfeU"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31632">
        <property type="entry name" value="IRON TRANSPORTER FTH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31632:SF2">
        <property type="entry name" value="PLASMA MEMBRANE IRON PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03239">
        <property type="entry name" value="FTR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0410">Iron transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="89"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="139"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="171"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="202"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="278"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0019785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="334" mass="36591" checksum="42285F454A9F88D5" modified="2023-09-13" version="1">MGSVFSAPIFFIMFRETTEAAIIVSVLLSFISQVIIDDPALYRRLRWHVWIGVLIGLIISLIIGGAFIAVWNSVAKNVFQTSEELWEGSFALIACVMITVMALAMLKSQDMQEKWRGKLSQSMDNMDNKKGVGKFTRKYALLILPMITVLREGLEAMIFVGGVTFEEEPKAIPLAAICGLLAGALVGFIIYRGGNRLALHRFFVFSTCFLLVIAAGLFAKAINAYEMDKWNKIVGGDADDAGSYDPRGNVWALSYGNPNDPNAGFAAFCNSVVGWNNIASVGTIVGYIVYWFVVIASVIFLKFKNRRARANATPVHVDEKAATAHIEKTAAALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1E7</accession>
    <name>A0A9P6N1E7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_004447</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000227">
        <property type="protein sequence ID" value="KAG0020285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1E7"/>
    <dbReference type="OrthoDB" id="26719at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0020285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="71" mass="7697" checksum="19779AFDBC528528" modified="2023-09-13" version="1" fragment="single">PISSTGIQVHARTPDFPQKGWSIEEGLLDQDHCYAVAAQTNIAGDGQMMDGSGIKRLNWAELLKDAAPYPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1H7</accession>
    <name>A0A9P6N1H7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_004388</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000224">
        <property type="protein sequence ID" value="KAG0020336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1H7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0020336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="459" mass="52801" checksum="38A914578F5A462F" modified="2023-09-13" version="1">MNNNNIIDIPEIAQVVASYLAPADLFIACRVSRSWFIPFASELWRSIKPDQWTHGALEDALPRYSLYIRELHCPLYNSLDKLGLDCTKLTLFRAPLLNANNAQVITSILRRNPNIEELSLISGLTREQLDISMEYVRIVSEMKKLKNLSLHHFIVRPGSLENLLQRLPQLESLSIRRYNSYQLPVSDATKEFDRSMGSSIDLNQLPQHSEYQGPRQLRYFHVDGYQDSFESILKVARISPLMERLSLAETYEYSIDLSLSPAVIQFCQELSSLCHCLDQLTLYQIQIDPQGLMCLLAAFPKLKRLDLEDVSLQAYDILRAVLQSPSYSHTLEEIRFVDHPTYFRQPTSHEILVMLRTFSKLRKVVLENCIIKAEEMVSNLGDNEIEDTESHNSDLSEEEESALGEFGKYGFRSRELEVLKVTIVGPTSRWAPPLNFAWDHTFNLDDDDGEEDEGVRFSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1K7</accession>
    <name>A0A9P6N1K7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">E3 ubiquitin ligase complex SCF subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_004427</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Essential component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the SKP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000226">
        <property type="protein sequence ID" value="KAG0020302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1K7"/>
    <dbReference type="OrthoDB" id="2342932at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18322">
        <property type="entry name" value="BTB_POZ_SKP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.710.10:FF:000026">
        <property type="entry name" value="E3 ubiquitin ligase complex SCF subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016897">
        <property type="entry name" value="SKP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001232">
        <property type="entry name" value="SKP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036296">
        <property type="entry name" value="SKP1-like_dim_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016072">
        <property type="entry name" value="Skp1_comp_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016073">
        <property type="entry name" value="Skp1_comp_POZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11165">
        <property type="entry name" value="SKP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01466">
        <property type="entry name" value="Skp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03931">
        <property type="entry name" value="Skp1_POZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028729">
        <property type="entry name" value="E3_ubiquit_lig_SCF_Skp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00512">
        <property type="entry name" value="Skp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81382">
        <property type="entry name" value="Skp1 dimerisation domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="SKP1 component POZ" evidence="6">
        <location>
            <begin position="8"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="SKP1 component dimerisation" evidence="5">
        <location>
            <begin position="110"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="149"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR028729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0020302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="158" mass="17664" checksum="F7373F8885E65643" modified="2023-09-13" version="1">MSSQSSQILLTSSEGTEFLVDRDIADKSMLLKCMLEDIGEIGQAIPLPNVSGPILTKVIEYCTHHRNDPNFQSANDDAAADIGEWDLEYCKIDQGTLYELILAANYLDIKPLLDLTCKTVANMIKAKSPEEIRKTFNIPNDFTPEEEDQVRRENELGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1W5</accession>
    <name>A0A9P6N1W5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001644</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000138">
        <property type="protein sequence ID" value="KAG0021816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1W5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="211"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="234"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0021816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="532" mass="60014" checksum="5B3AD57696892FC8" modified="2023-09-13" version="1">MNQRPNPLEIPEILSRVGLYIPLWVHSSEYSSRPRSWRPRFAPQHLLNCILVNKTWHDILLPILWFSLDDISVPSLLHAFNALSRHSRHLRILELSRLALGTISLPLSLLPHNLLHLNLNGLGNNQWARALVLQNTRLQSLRWQGGDFHRDNYYETLDALALSKRLHRLQDLCLECWKLDGSFMKLLRKNPSLKRISLDYVSGEVQDKFTPWDTTRRNQGGTLKGSEGEKEEEKNDDDDDDDDNEDEETEVILPDLVSLTVCKDVESGALEALIRLCPGLEELSWMGPNDGDLRQLTTNIRECCPSLSALTYSTVDISEDESLYAELIRSVPHLVELQIKIPALGDAFTEALIKHAPTLEILELTISGNHVNCNANFKKILTSCHQITALSIEGSKCGAASLFSFNWACLRLNRLLLVGLQSIAQDPPYNTDSESIAAMYGWTVATGGDGTVVSPIQHEIFDQAEGEGIDGVTTTEEIRQYAEGQDAAPQICTRFLRRLLTHLQTMRHLQSFFLNGVEYTRTLTDCSEPIYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2K8</accession>
    <name>A0A9P6N2K8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Class E vacuolar protein-sorting machinery protein HSE1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Class E vacuolar protein-sorting machinery protein hse1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="primary">HSE1_2</name>
        <name evidence="16" type="ORF">BGZ80_010997</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endosome membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the STAM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000083">
        <property type="protein sequence ID" value="KAG0022846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N2K8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033565">
        <property type="term" value="C:ESCRT-0 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043328">
        <property type="term" value="P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11805">
        <property type="entry name" value="SH3_GRB2_like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16978">
        <property type="entry name" value="VHS_HSE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000072">
        <property type="entry name" value="Unconventional Myosin IB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004152">
        <property type="entry name" value="GAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050670">
        <property type="entry name" value="STAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003903">
        <property type="entry name" value="UIM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002014">
        <property type="entry name" value="VHS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45929">
        <property type="entry name" value="JAK PATHWAY SIGNAL TRANSDUCTION ADAPTOR MOLECULE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45929:SF3">
        <property type="entry name" value="JAK PATHWAY SIGNAL TRANSDUCTION ADAPTOR MOLECULE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03127">
        <property type="entry name" value="GAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00790">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01887">
        <property type="entry name" value="SPECTRNALPHA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00288">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89009">
        <property type="entry name" value="GAT-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50330">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50179">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0967">Endosome</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="13" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040201946" description="Class E vacuolar protein-sorting machinery protein HSE1" evidence="13">
        <location>
            <begin position="29"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="domain" description="VHS" evidence="15">
        <location>
            <begin position="35"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="14">
        <location>
            <begin position="190"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="131"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="364"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="414"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="142"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="367"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="414"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="438"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="453"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="479"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="514"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="540"/>
            <end position="555"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0022846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="563" mass="63702" checksum="9A2B43286EC30D25" modified="2023-09-13" version="1">MQTRPTQPNFNSAASPVLALLIWKCLHGNAYTAGRDCLAAIQKRLSNKNANVILYSLTLCESLAKNCGLKAQREISSRAFTSLLVKILNEKTTHPAVRQRILELIQQWAFEFRADPSLGIMDETYHQLRSQSKFKFPSPQKPKKELKSEADKRKEEEELQLALALSLSASEHSERQISSRPSQHPEVAAAPVKRVRALYDFEPTESGELGFQKDDIIVVLATSYQDWWKGELYGRQGIFPVNYVEEIKEGEPGQNGGSGDDEAHVLHEAKNIDSLIRMLQNVDPRRDNFSDNETLQDAYNNVLGIRPQLVELIKKYGEKKDEMLTLNEKLMRARSTYEKMMEQSIARYSNPAYTAYQPQLPAPATPYYNQPTQLGQNGYSATPYQQPQYAPAAVQGQAPVASYQQESQYMPYIPQQQPQQQQQIQTQPQIQPQPQPQQQPQQQPQQQPQQQPLTFDQAFQGQAPPQSQPPVDYGVNGAQQQQQQQQPLQQTQSYQGYQQQPQQQPIGGNDFSNQQQQQQPAFIPQQSMIPDSQGMFAPNPSVSYGQQPNGYTPQPQFAAAPFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N382</accession>
    <name>A0A9P6N382_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Iron hydrogenase small subunit domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_001274</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NARF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000129">
        <property type="protein sequence ID" value="KAG0021980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N382"/>
    <dbReference type="OrthoDB" id="10253113at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1780">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.950.10">
        <property type="entry name" value="Fe-only Hydrogenase (Larger Subunit), Chain L, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050340">
        <property type="entry name" value="Cytosolic_Fe-S_CAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009016">
        <property type="entry name" value="Fe_hydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004108">
        <property type="entry name" value="Fe_hydrogenase_lsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003149">
        <property type="entry name" value="Fe_hydrogenase_ssu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11615">
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    </evidence>
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        <source>
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    <sequence length="559" mass="61242" checksum="6ADA15DC5ED80470" modified="2023-09-13" version="1">MAFSGALTLSDLNDFISPSQACIKPVEVSKTSETQGAIKVDNSGAYYEVSQDGSETKLETASITLNDCLACSGCITSAESVLVTLQSQEELYSILKQNKIAIETNDPSTHRTVVVSISPQTRASFAAKYNQTPLQVARKLTWFFKNLGVHSVFDTTFSRDLSLLETGREFVERYKKAVAKGIIKTPNMNGPPSTTAESGGDMDVDTPQEPATKAPRKRIVRRGAASDEPAVAVETESAMPMLASACPGWICYAEKTHGYMLPYISETKSPQQIMGSMVKNHFGSQLGLTPNQIYHVCVMPCYDKKLEASRSDFYSDLYKTRDVDCVITSTEVEKMFGEQGYTSAETLDISMFGEMDLDLGYNSVVKDPVTGVDQALIGSSGNASGGFLEYIMQYAAKALFGIGGIDVENSQGVEVKTVRNADFREVTLEVPGTGEVLLKFAAAYGFRNIQNLVRKVKTGKSPYHFVEVMACPSGCINGGGQLKPHGNNYTTVPLKDWIARVDEQYRNGVMARKPEENPVLEQLYQEWLGGIDTPKARQQLRTGYHAVEQNLVNPLAVKW</sequence>
</entry>
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        </submittedName>
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            <taxon>Entomortierella</taxon>
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        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
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                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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        <property type="protein sequence ID" value="KAG0023125.1"/>
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        <property type="component" value="Unassembled WGS sequence"/>
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        <property type="entry name" value="MIT_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="MIT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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            <end position="61"/>
        </location>
    </feature>
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</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3F3</accession>
    <name>A0A9P6N3F3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA replication checkpoint mediator MRC1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_001079</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
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        <lineage>
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            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
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            <taxon>Mortierellomycotina</taxon>
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    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
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                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
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    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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        <property type="match status" value="1"/>
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            <end position="1073"/>
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        </source>
    </evidence>
    <sequence length="1363" mass="147957" checksum="E15D0A830842E24F" modified="2023-09-13" version="1">MASGMDKGLMALMGIEDDIPKDEGLAPVNTAGNMSPLQSSQDMPSFFDDEESAFLSDQDVDIEMKNYSMSHSAKNTPSSQRTTDFAGAAVSPQAHINAVTSTPRASTSSLFASPVSSSQEESLFPPNFTPPDEPLPRDIRVLLKPVTSSPPFFSSDSNPFGRASPGKVRISRSSSSSSPSPSLFSPEFNPFARPPSDKIRVKKKSSSQGGDGSSMFSPTLSPRKTKKKHSPSSGSSSRSHINTSAPSNAASVLKTNRTGKSFRASPSPTSATEARAADGLSSPISSFSLSRKAAAMFSDSDSDISPIEDNISSSKSVPHDIVLNISMSSDMDTEMLSLNKSPSFTDSRNSLPQDQGEHEKRGQSHNTEWDEDEVMLVDTQAKRSVKAQKEMLKVHMEANKLMRGSSLPIKPRVSKTYNLSELMKQSQSKLDEKKNTARVPYLYTGNIQPSISERQNHSLNSNPPKPKIKTVALSDGSEDEPDTGPVAFSQSRLDAAKAFLIAPKQRRPGPAKLGIQPVDMSPQGESSIPMSPLSKNVSKMSISGGYGGATSSHQPSNDLRQSFITSPSKSQRSGAGINLLKEDIRRKQAKSNMELRKKLAMEAKKSGKWMAPEEHAAEQMLLEEDADDEGDEDYDPKGTGGKNAQDNDGDMDEEEDGDYEENEELAIERGSADEAEALSGESEGEDKRVDGDNADDVADSGSNIEEESDGDDDDDEEKEEEEAEQEAEAIKVKARRPNAKKAIIEDEDELNVVIVNRENLLTESEDDDENRGSDENSDEATSDSGDDDDDAGAHESQDVDGSPGFGNFFAPSMDQNVTKKQNVADNPTPTIESSITSMPSSDPSPNQSEDFSQSQSLVIPSGILSAKFTPSVPDSSNPLSINASIGKEIADIESPNVDDSQSLASGDLPQPRNAFDVLTGAQGLRRLRKKEASLRESIPKGAKSAFIEYEAEEEDDEHKGMGGIDYESDNDQDDYDLGDGMIDTTAALDSQDAEDVRKLHMKHEQEQHDKDISDLVHGIAAGNLWKRRNGQGDDLDIFDEEDMDGRFQRKKKLKVTEKFEKLADNPSTAAFARALKKEIDDDHIVFLSDPDESNDEADAGGKGEKADNNDNEDEEMAAAEPSDDEISVDKSLSNPGYLEDEDEEEDEPLNTDKRKENLRLARLRNNSETSKSGSTVTAWTKTQTLPFGPSSSEHTFMKTGNITSTTLVETEDSAKGGDKDSIEDHIDDYNNLLKRSKLIRDIVDGVIDPAGPSVELIAASSSSSFSHRSTEMIDDLESTSFLRTREEVSISAVDPSLRTFAKPRMLARQSSSFLEEERRGLFLSTVGEDGVGSVKDVNRRKMAFGAATAPSESTGSASSRQRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3Q2</accession>
    <name>A0A9P6N3Q2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">GTP-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_009203</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">GTPase involved in activation of the TORC1 signaling pathway, which promotes growth and represses autophagy in nutrient-rich conditions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the GSE complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the GTR/RAG GTP-binding protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000053">
        <property type="protein sequence ID" value="KAG0023521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3Q2"/>
    <dbReference type="OrthoDB" id="26136at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990131">
        <property type="term" value="C:Gtr1-Gtr2 GTPase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009267">
        <property type="term" value="P:cellular response to starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010507">
        <property type="term" value="P:negative regulation of autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904263">
        <property type="term" value="P:positive regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11385">
        <property type="entry name" value="RagC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000643">
        <property type="entry name" value="Small monomeric GTPase (Gtr2)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006762">
        <property type="entry name" value="Gtr1_RagA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039400">
        <property type="entry name" value="RagC/D"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11259:SF2">
        <property type="entry name" value="GH16429P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11259">
        <property type="entry name" value="RAS-RELATED GTP BINDING RAG/GTR YEAST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04670">
        <property type="entry name" value="Gtr1_RagA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="276"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="309"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU367014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0023521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="422" mass="47652" checksum="62A3D788248C1FDC" modified="2023-09-13" version="1">MSYSDYGDNDPIYGDDLAEEDRESRPRLMLMGLRRSGKSSIQRVVFHKMSPTETLFLESTSKINKDNIHSFIDFQVWDFPGQMDFFDPTFDTTAIFGEVGALVFVIDSQDDYMEALARLHTTVVAAHRVNPNITFEVFIHKVDGLSEDYKIDTQRDIQQTTMDELSDAGLENVQLAFYLTSIYDHSIFEAFSKVIQKLIPQLPTLENLLNILCANSGIEKAFLFDVISKIYIATDSSPVDSQSYEICSDMIDVIIDISSIYGRAAIGAKSQGYLEDHQDGQDDWTQQQDGHGDYEDTNGGIHQRPGASDMNSQTVVSNSSRAGSLNSVPTQQTSGNHEAFSVIKMGNGTVLYLREVNKYLALICLLKAETFEKQGLIDYNVHCFKEAMDQVFELKRAERTRREMEANQLLEEQRHNGMYGHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N460</accession>
    <name>A0A9P6N460_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">2Fe-2S ferredoxin-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BGZ80_002425</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the adrenodoxin/putidaredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000016">
        <property type="protein sequence ID" value="KAG0024474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N460"/>
    <dbReference type="OrthoDB" id="268593at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140647">
        <property type="term" value="P:P450-containing electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.30:FF:000013">
        <property type="entry name" value="Adrenodoxin, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001055">
        <property type="entry name" value="Adrenodoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018298">
        <property type="entry name" value="Adrenodoxin_Fe-S_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23426:SF65">
        <property type="entry name" value="FERREDOXIN-2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23426">
        <property type="entry name" value="FERREDOXIN/ADRENODOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00355">
        <property type="entry name" value="ADRENODOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="2Fe-2S ferredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00814">
        <property type="entry name" value="ADX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="6" id="KW-0249">Electron transport</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="11">
        <location>
            <begin position="91"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0024474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="206" mass="22392" checksum="5461EA5DF494CAD6" modified="2023-09-13" version="1">MVLASTARRAALVSSSSQSYTRAFSGICLSTRNYFSRSGANSFRFRSSSWIRISSPNDIPKKNSINQLAKFSTGSVWQHGALPRPAPGTGIKVNFIKPDGEKVTVEANDGESLLDVARANDLDVEGACEASLACSTCHLILDEDSFNKLEEPSDEENDMLDMAFGLTDTSRLGCQVLMNKELDGLTVKIPSATRNMYVDGAKPKHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4N1</accession>
    <name>A0A9P6N4N1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007851</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000041">
        <property type="protein sequence ID" value="KAG0023829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N4N1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="509"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="643"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="725"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="518"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="538"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="653"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="674"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="748"/>
            <end position="759"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0023829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="791" mass="88609" checksum="AFC24B45C07F1C62" modified="2023-09-13" version="1">MEETLGIPEMRTIIAQFLALKDLLVCTLLSKAWNETCSPLIWRKVLIGGSKIPSLSAMKKHGQYIRVLLLENTKGIEPLLAHCNHLTVLKLLTFLDEEEDDDDDDDDDDDKDGYSDEFIQFLARNQATLRVFENHWSEPEIPKEALVILLSCPNLEELVTTGVTYDDVTWELLVKAGCRLSKLISIDDTITSQALAAPPPPSLRWETITTLSFQYPHVDDEPGFVVDCIKRCPQLRSLIWDSKASFPIKAFVEQVLPACPKLDSLSIQNFGIEDADISKVLEAMNQLRLVKIRGICDDTGTATPGLKIFGAIRKHFSTLESIYFRAAYHIKSEYVAEILESCPSLRLVEALDINADHIHDTPVWACTGLRIFRVCIVGVKSDNSHRVFKQLGRLRQLYELDIHPEGNKVTDGLNLTQKAGLGAMEGLKELRFVSTMSVMQTLDKDDVDWITKFWKNLRVWEGQPHHDKDKLLTIEKEFRKHGILIVRFLVPSPNVESSLPVYTHSPPVPSAPPVLHTPNRSDAQPLTSAIKTHSSITKGEDDKIPSKGTRFADPEDSPPPGQEEHQPRNRNVTFQTRPRADTAESSNSVVFPTFAAYRQAQSNKTMDAFAKRVKKAFVLSQQQQEQARIEEILRRQQAEEEEEERQLRELEEQQQQQQQRQQQDIPMPTTRQRSSSNALPMSSPSVPAGGNRLRSSSAASMFSDIAERIRNGTLFKISSNNTSTAVADMNDKQSEQSSRVGGGENGESELGGLLGIEILVTSPENDHPITDDDAAASTSIGHVRIDTDTEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N6P7</accession>
    <name>A0A9P6N6P7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">OPT superfamily oligopeptide transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_010275</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000007">
        <property type="protein sequence ID" value="KAG0024696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N6P7"/>
    <dbReference type="OrthoDB" id="9986677at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035673">
        <property type="term" value="F:oligopeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004648">
        <property type="entry name" value="Oligpept_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00727">
        <property type="entry name" value="ISP4_OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22601">
        <property type="entry name" value="ISP4 LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="85"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="158"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="186"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="228"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="266"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="301"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="373"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="428"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="457"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="539"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="577"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="609"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="650"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="688"/>
            <end position="709"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0024696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="761" mass="85665" checksum="C76F9675B431C90C" modified="2023-09-13" version="1">MTEKYDPDAEKAYTDEKQIGETIDLVEEEEPENSKVEAVRLAIPLTDDPSMPVITFRFWVLSFIFSAIGAVIMQYYYFRATTGTYSIYFVNLVSYGLGVLMARYLPTRSVTIGSYSLSLNPGPFNIKEHALIGIAVSTAANSAYAIDILAATDLMLHYRIGAAGSLILILTTQCLGYGMAGSLRKYLVYPAEMVWWSNLVQIVFYNALHGTEKFGKQKMVRGWSYMQFFWIVAGITFVYEFLPQFLGPLFLYFDWVCWINPFNRDVWALFGSLEGGGALSFSFDWTAIGGSTLYYPFYSQMAYYGGVIFNYWIILPILWLTNSMSIRDFPLVLTSHLFHKDGTPFNVVPVLNPDYSLNETLYEEGEPAVMTPMYALAFMVGFIGLAACVSHIICFHGRDLIKTWRSVANDKDTDIHVKMMSIYPEVPQIWYAIFYIIMLALSIFVCEEYKLQLPWWGVILAAAIGWIMSLPICAMQAITGFSPGLNIITELICGYMLPGKPLANMTFKCYGYMAMYQCQNFLQDLKLGVYMKIPPRSMFIAQFWGTVVGGILNYYTMLVIIDVHRAYLDGTDQDPNGLWTGVSTQIYWGSALIYGALGPRRMFSSDGPYGFVFWGFLIGFILPVIQWGLSKKYPSVQWEKFNVTVITIGMSAYVGGYVNGVLFSVICVFIFGFYLFRYRKAWWTKYTFILAVALDTGAAFTGLILFLFFSGGISPSIQVAAPSWWANYVTPDGDNGPYLDVDRCGASGNWTSGLSGYGISS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N709</accession>
    <name>A0A9P6N709_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Mannosyltransferase</fullName>
            <ecNumber evidence="12">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">ALG12</name>
        <name evidence="14" type="ORF">BGZ80_002062</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Mannosyltransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. In the lumen of the endoplasmic reticulum, adds the eighth mannose residue in an alpha-1,6 linkage onto Man(7)GlcNAc(2)-PP-dolichol to produce Man(8)GlcNAc(2)-PP-dolichol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>an alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate = an alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:29535"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="Rhea" id="RHEA-COMP:19518"/>
            <dbReference type="Rhea" id="RHEA-COMP:19519"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:132517"/>
            <dbReference type="ChEBI" id="CHEBI:132519"/>
            <dbReference type="EC" id="2.4.1.260"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:29536"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Endoplasmic reticulum membrane</location>
            <topology evidence="1 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the glycosyltransferase 22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="12"/>
    <dbReference type="EMBL" id="JAAAID010000015">
        <property type="protein sequence ID" value="KAG0024502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N709"/>
    <dbReference type="OrthoDB" id="19039at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052917">
        <property type="term" value="F:dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005599">
        <property type="entry name" value="GPI_mannosylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22760:SF1">
        <property type="entry name" value="DOL-P-MAN:MAN(7)GLCNAC(2)-PP-DOL ALPHA-1,6-MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22760">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03901">
        <property type="entry name" value="Glyco_transf_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="157"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="191"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="244"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="281"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="372"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="397"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="418"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="445"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU363075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0024502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="626" mass="69770" checksum="B9785E8506A34C0B" modified="2023-09-13" version="1">MTTSEMEEQQKHSNGILQNGHRKGSFKSNELKARPKSVQFQTTTTTITTTRPRSLSSDFDGDPSTTFTYYSYSTSSTASSSSSSRGSTTKSLTAVEYLAHGAVFSLILAHILVAPFTKVEESFNLQAAHDILTFGVSDEGVNQYDHLEFPGVVPRTFVGPLLLAIGSWPIMALTRLFAVGSSLPKGVLGQIIVRATLGLFTFMGWYQMTLGVRHQFGKITSLLFLLVSSVQFHWLFYAGRTLPNTFALAIVNVSYSYWMQASSGNSRTYTEQRLLRMIDCLVVSTVLFRSELLLLLAPITLLELSMTRIRLIPTILEGIKAGFASLAIAVAVDSWFWRQWMWAEGAVFWFNAIQGKSVAWGVSPWHTYFTSLLPKISGVALPLALAAVVIEPRFRRYMLPAGVFVGLYSFLGHKEWRFVVYVVPILNLGAAIALSWVIKRKTLAYRLLAVALFGALGLNFLMSVAQSLISSHNYPGGVALQRLHELDLHRFTAAYVHIDVVAAETGCSRFGEIGSQATPYLWTYSKNESHTSRKDYLHYTHLLTSTPEFHKHDFIILEQIDGYAGLDRVPLGRIIQTCPRAIKGLVSNFSLSKLSKDTVDELLKECSPLQIKKEGKIWIMRRFGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SRC5</accession>
    <name>A0A9P6SRC5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Condensation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008089</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004291">
        <property type="protein sequence ID" value="KAF9993575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SRC5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043041">
        <property type="term" value="P:amino acid activation for nonribosomal peptide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensation_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF1">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Condensation" evidence="1">
        <location>
            <begin position="12"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9993575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="293" mass="32186" checksum="484216682175DC32" modified="2023-09-13" version="1" fragment="single">MTKLTDPRGCRIDLTQAPLIRFVITEDFDGKWIVVIHLHHIIGDHSTLDLMMVEIRAFMKDKERTLAEPQPFRNLIAQVSSSQGLDIHERFFIEMLAEIDTPSLPYGLSDVHRDGLDVTESHLLLPQDLNDRLRGYAKRMGVSLASLCHLAWAQVVAKTSGQEKVVFGTVLFGRMQGGSGSDQAMGIFINTLPLRIDIGDKSVEESVRQTQADLAALLEHEHASLALAQRCSSVPAGTPLFSALLNYRHNATPSVDASEIVGVKALDGQERTNYPFMISVEDGGSSLGLTAQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SRJ3</accession>
    <name>A0A9P6SRJ3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_008153</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004339">
        <property type="protein sequence ID" value="KAF9993414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SRJ3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9993414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="58" mass="6396" checksum="3E62C1A577833CDB" modified="2023-09-13" version="1" fragment="single">ENSSELFWSELQSKVDTIISSRKAGIITRAAGLEQAANDYKNHLSSENQVIRSQATTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SSP7</accession>
    <name>A0A9P6SSP7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_006822</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003393">
        <property type="protein sequence ID" value="KAF9998252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SSP7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF309">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14510)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9998252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="166" mass="18615" checksum="F670F0DE9FDC1CB6" modified="2023-09-13" version="1" fragment="single">MSQDTPEARSRPEVLIIGAGIAGLTPAILLEQIKVPYHIFERAAGVKPLGSSPVDENRIASGYEPLIFCRPRFYEILLRRIPEHKISFKKKVLCIEEKEGKVRIHWSDDTSYTGDILVGADGAYSEVRQSMYKLMDEKGTLPKVDLENFKINYTTIIGVATPPNPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ST94</accession>
    <name>A0A9P6ST94_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_006360</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003138">
        <property type="protein sequence ID" value="KAG0000446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ST94"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="464"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="326"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="685"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0000446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="685" mass="75489" checksum="147B837E0079E42D" modified="2023-09-13" version="1" fragment="single">MDCLGLENEVYSDFDFVYNLFSMFPLISSLVIKDRYMRDRDMRVVTAGILAGKMAFTEAKGPVIGSDAYRDAQQAVAIRCQQQDGSTPEVRPAQHNTTAKPVLKVMRKTIKEDLQEFSRSIATYVLIPQTRNTLRKKILERLEHNLEQKEIQDYFWMLENDIDPSTSHLLTSTSVIATASASSLSKKNTYPLVPITHYRFHDCCFAKDWGAVMDVNKLPMIGLAASITAQGLVVDLEGSYGAPSQSIKTMLGFCFGAHCVLSLELNFRHTHMELEHVVELLSENPILYKIDIVDSPAFHDLIRLPALRGLGSIVEKMQEACLDLDEIQLEESLQDAKLVLLELERAIELEETAKKDDLSKKQTNEDPVLAVPDEEVSASYPTYTERPPRVVNDLRKPIQSLSKQLVYVSGTPPAGRLRTAKVLLMGVIHHGIAGLINTRDRNTGQSLLHTLAWRRSYYSLTTIPTDSLPTPPSQHQRWKGPETNTSPFFSSSFPPSSPLPASGTSSLLPTYPSPNLVHHAAEPIVDAVTEPQPISEEPQVTTTSSGLSSLISISTLPAALSSALSFRRLSLPATLWIPMDSEDIGVGGGSLPTPDLDDDEVHSPFLDNSVGTITDVELIYDSTVEPTEAAAVATETQEGLTDDKADRPLVIPEQHPVAIALRMAKVLLEMNANPNVYNKDGRSAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6STG7</accession>
    <name>A0A9P6STG7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_006572</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003253">
        <property type="protein sequence ID" value="KAF9999412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6STG7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01344">
        <property type="entry name" value="Kelch_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="124"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="91"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9999412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="203" mass="21842" checksum="AD58365F5BDEAF8E" modified="2023-09-13" version="1" fragment="single">YNGTKMILFGGQDTSNNPTNSIYILDLSNQTWTMGNNIDISLSRNGGACASYGDNFIGWGGNYHGTFPSQLSTVVIYNLKFSQWTTQYTVPGSSTSSTSTTGTNSPGSTNTDVSSKSNSTTAPIVGGVVAGVLVLAIGGYFIRRRLKSTEGELAKAELGEREVPMKMQEPQPQQLVNSRSPQFGNQLGYEQIPKSGPQQFYQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SUA8</accession>
    <name>A0A9P6SUA8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005919</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002917">
        <property type="protein sequence ID" value="KAG0002735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SUA8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0002735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="137" mass="15438" checksum="72F35872DEA207D5" modified="2023-09-13" version="1">MHPGAEAVNTDILRLAIFTKDSLDLLHRTLERGPPLVTFQTVGSDVVFFLGARVDNAIVHTRLSSTKLPSNLTELDLDHDFFFNLFQVQTLINVTKDRLEEKRIAPLEEASFPTLGTPDRNEALNSPKKSRKLKQRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SUG7</accession>
    <name>A0A9P6SUG7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_005704</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002800">
        <property type="protein sequence ID" value="KAG0004034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SUG7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052945">
        <property type="entry name" value="Mitotic_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43628">
        <property type="entry name" value="ACTIVATOR OF C KINASE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43628:SF1">
        <property type="entry name" value="CHITIN SYNTHASE REGULATORY FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0004034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="289" mass="32608" checksum="D9B2B5F924B8C6F8" modified="2023-09-13" version="1" fragment="single">PVEHDHLKAYQRYLEAANQGYADAQSNLGFLYQVGYGVIKDEAKAVEWYKKATERGHIYAHCNLGFMYDRGVGDHSQAVEWHQKAVNQGHDDAQLNLGNSYKDGHGVTQDYAKALDLFRKAGDQGNEVALFNLGAMYHSGRGVKQDDSKAFEWYQKSAKEGYADAQYYMGIAFRDGDGVTQDYLQAEEWFQKAADQGDAESQYILGVMYQNGHGSIQDYSKAIELYQKAAEQNHILAQYALGLMYENGNGTSKDISRAMEWWRKAASSGHDEAQELLGKYQNNPQVYFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SUR3</accession>
    <name>A0A9P6SUR3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Carrier domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_005496</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the NRP synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002704">
        <property type="protein sequence ID" value="KAG0005184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SUR3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043041">
        <property type="term" value="P:amino acid activation for nonribosomal peptide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072330">
        <property type="term" value="P:monocarboxylic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05930">
        <property type="entry name" value="A_NRPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19544">
        <property type="entry name" value="E-C_NRPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.30:FF:000010">
        <property type="entry name" value="Enterobactin synthetase component F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1200.10:FF:000016">
        <property type="entry name" value="Non-ribosomal peptide synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12780:FF:000012">
        <property type="entry name" value="Non-ribosomal peptide synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.980:FF:000001">
        <property type="entry name" value="Non-ribosomal peptide synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.38.10:FF:000001">
        <property type="entry name" value="Non-ribosomal peptide synthetase PvdI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.980">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.38.10">
        <property type="entry name" value="Luciferase, Domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF1">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="894"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0005184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1248" mass="137401" checksum="A8DCFD5E0BF69578" modified="2023-09-13" version="1" fragment="single">MWERLSKPAQVVLRQAQLSITELSLDPANGLIIDQLSRRFDPQEYRIDLTQAPLMRFVISQDIDGRCIVIQLLHHLIGDHSTMDIMSNEINVIFEGNDNELPTPPPFRNLIFQARSGFGVEAHQAFFTKMLSDIDTPALPFGLSDVQRDGIDITESQLTLPQHLNNSLRGHAKRMGVSVASLCHLAWAMVIARTSGQQRVVFGTVLFGRMQAGSGSDRAMGLFINTLPLRVDVEDASIEDSVRKIQTDLAGLLEHEHASLAIAQRCSSIPAGTPLFSTLLNYRHNSVSSNESSDIAGIQYLEARERTNYPLDISVEDGGSSLGLTVQVVRSIDANRICGYMQQALQSLADALDTAPKMTVKDLDVLPLEERQLLLQSSISMEQDYPADKCIHQLFEDQVNQTPDAVALVFDGQTLSYSELNVRANILAHHLIQLGVEPDALVAICVDRSLAMIVGLLAVMKAGGAYVPLDPTYPSSRLKYMLTDAAPAILLADNVGRLALNDADLSSLTLLDPSYAFSGLEVNPSIPTLTSCHLAYVIYTSGSTGAPKGVMIEHQGVVNQVNTRPAVLGVDSTSRVLQFSSLSFDGSVDEIFSALCFGGSLHVLSDRTRFDRTRLWCYLEEYSITQAELTPALLQDCKDLPPLSTPLALILGGDALPPTLLQKMKDLIPNGYIVNAYGPTETTVDAVIWKCSSDFNGEVVPIGRPIANKRVYVLDADKNPVPLGAVGELYIGGVGLARGYLNRPDLTAKAFLPDPFMEESGGRMYKTGDLVRYLPDGNLMFLGRNDHQIKIRGFRIELGEIEACLAEHPVVREAAVVVVGEVTDKRLVAYVVAEPRDRLASMLRAYLTTMLPGYMIPAAFIRLDVLPLTPNGKLDRRALPAPDSAAFVSQEYEAPQGEIESSLAAIWVDLLKVERVGRHDNFFMLGGHSLLVVQMIERLRRIDLALSVRSLFDTPTLSVLAQSLSRHYVSNAAPENLITPQTMNITPEMLPLIDLTQDDINTIIENVEGGVSNIQDIYALSPLQDGILFHHIMATKGDPYLLIHGMAFNSRELLDRYLDAVQKVVDRHDILRTAVMWENLSKPAQVVLRQAQLSITELILNSSDGPISDQLNNLFNPREYRIDLTKAPLIQFAISQDVDGRWIAIELTHHLIGDHSTIDIMQNEIQVILEGRGDTLAALHPFRNLIAEVRSGPGAEAHEKFFTKMLSDIETPALPYGLADVHRDGVDITESHLSLPQHLNSRLRGHAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SUZ6</accession>
    <name>A0A9P6SUZ6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_005367</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002650">
        <property type="protein sequence ID" value="KAG0005975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SUZ6"/>
    <dbReference type="OrthoDB" id="6499973at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF284">
        <property type="entry name" value="EG:103B4.3 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="194"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="232"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="267"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="294"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="327"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="359"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="399"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="138"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="40"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="50"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="76"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="140"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0005975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="447" mass="48798" checksum="C4040C0102D22A56" modified="2023-09-13" version="1">MSSPPDIPQIRTTDTDTHTSTAAENTPDYYATTTTGNRDNDDDDYDDDEKGQYHYIDKSYHSLPDDGEVLQPNQRRAMDSHEANHDSLASTSLGLAFSDPMLAITQLPNAGRRSSIASSLHSNASSLRRQRLFQSSYPTVDEKKAPVQEPRKSQEAGLGSVREEGIPTDRQLEAFTMPDLPEVDDGSPPMDSSWYGYVIVVCCFIVYFIVFGTEHTFGVYQEFYTSSSAEPFLQGATSQQIAMIGTLATTFTYLLGAFSGRFADRAGFRISTILGAVIMGTGFIGASFTKSIAGLYICQGVILGVGSSLVYLPAISCPAHWFEKYRSIAIGVVVCGSGLGGLVLGPLVEYLIARLGIHWTLRIQGLLCLVGIGGSGMMLKTRVKKVAGQSKRIPMDFTICKEVPFITLTLANFLTSLGYMIPFFFLSSKSCVDMTVPFVFITVFQCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SVW0</accession>
    <name>A0A9P6SVW0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 15">Dolichyl-phosphate-mannose--protein mannosyltransferase</fullName>
            <ecNumber evidence="4 15">2.4.1.109</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BGZ80_004758</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14 15">
            <text>a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17377"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:13546"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:137321"/>
            <dbReference type="EC" id="2.4.1.109"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 15">
            <text>a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + L-threonyl-[protein] = 3-O-(alpha-D-mannosyl)-L-threonyl-[protein] + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53396"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:13547"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:137323"/>
            <dbReference type="EC" id="2.4.1.109"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 15">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 15">Endoplasmic reticulum membrane</location>
            <topology evidence="1 15">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the glycosyltransferase 39 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.109" evidence="4 15"/>
    <dbReference type="EMBL" id="JAAAID010002394">
        <property type="protein sequence ID" value="KAG0007351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SVW0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004169">
        <property type="term" value="F:dolichyl-phosphate-mannose-protein mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd23283">
        <property type="entry name" value="beta-trefoil_MIR_PMT1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003342">
        <property type="entry name" value="ArnT-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036300">
        <property type="entry name" value="MIR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016093">
        <property type="entry name" value="MIR_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027005">
        <property type="entry name" value="PMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032421">
        <property type="entry name" value="PMT_4TMC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10050">
        <property type="entry name" value="DOLICHYL-PHOSPHATE-MANNOSE--PROTEIN MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10050:SF50">
        <property type="entry name" value="DOLICHYL-PHOSPHATE-MANNOSE--PROTEIN MANNOSYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02815">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02366">
        <property type="entry name" value="PMT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16192">
        <property type="entry name" value="PMT_4TMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00472">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82109">
        <property type="entry name" value="MIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50919">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 15" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 15" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="81"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="132"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="164"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="197"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="251"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="563"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="606"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="629"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="658"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="17">
        <location>
            <begin position="303"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="17">
        <location>
            <begin position="365"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="17">
        <location>
            <begin position="434"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="771"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="792"/>
            <end position="825"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00045085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00045102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU367007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAG0007351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="825" mass="93559" checksum="1EC4B007507695F0" modified="2023-09-13" version="1">MSSGTSSALDQPVVPVYRGPQARANAKDTVEEPIAETHNGRSSTEEKRKREADSPYPDQDRSRLTKSKGRRSSPWYQSRDLQIATLITILAAVVRLWALGYPTSVVFDEVHFGGFASKYISGRFFMDVHPPLAKMLIALMGWLFGLDPSFTFKEIGVIVTQSRLILLDSPLIFFTAFTVLAWVNFHNQRHEAFSDDWFIWLFLTGAGLGLSLSVKWVGLFVIATIGMSTLNQLWSLWGDLRVSPRVWLNHFLARAVCLIVVPIAVYMLMFEIHFLLLESSGDGDGFMSAPFQMTLGHSLQDSPLSVAYGATVTIRHQGTQGGYLHSHPSNYETGSKQQQITLYPHKDSNNDWIIQKRDGTVPESLEYVKNGDYVRLVHAQTHKRLHSHDHKAPVTESESHFEVSAYGYEGFAGDANDDWRLEIVEFDGSNSTAGEQLHTLRSKFKLVHPNMSCDLFSHKVKLPKWAFEQQEVACMRSAVVSKTTWIIESNRHDAYPSDAPMVNYKKPGFLGKFLELNKVMWTTNAGLTDSHPYDSRPSSWPLLKRGISFWGKDQKHIYLVGNWFTWYASSVAIVLYAVIRGLLFLRDKRGYRDDFRGLREYYEMSGGFFFMAWGFHYLPFFLMGRQLFLHHYLPALYFAILLFSVTFDVASRFVPNKFRLIAVVLIVSTAVMVFRTRAPLTYGLQWTRSECEASKLLRTWDYDCNQYPVEYSHYVTTTPVPPQAKEEKLDPVGSEVDTSSQVASAAAAVGAEIPGVDVGKDTAVVDNVQEVSDINDPLVTDPASATVKEVRDEDDESEDEDEEEEEEEEEEEGDEEEEDEEEDEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SVY1</accession>
    <name>A0A9P6SVY1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Peptide transporter ptr2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">PTR2_1</name>
        <name evidence="10" type="ORF">BGZ80_004615</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002336">
        <property type="protein sequence ID" value="KAG0007478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SVY1"/>
    <dbReference type="OrthoDB" id="8904098at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071916">
        <property type="term" value="F:dipeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000085">
        <property type="entry name" value="MFS peptide transporter Ptr2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000109">
        <property type="entry name" value="POT_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018456">
        <property type="entry name" value="PTR2_symporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11654">
        <property type="entry name" value="OLIGOPEPTIDE TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00854">
        <property type="entry name" value="PTR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01023">
        <property type="entry name" value="PTR2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="130"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="179"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="270"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="427"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="479"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="511"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="538"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="33"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0007478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="584" mass="65305" checksum="3FAD1BE67ED86024" modified="2023-09-13" version="1">MKQEHEEVHHEAVEIAYKSDPMMTGIKSDLDSHKHSISHHEGDKYNMTEDLTGDGREPTYEEESTLRRVADTIPAAAWLVVVVEFCERFTYYGLSGPFQNYIQYPYTSERGADHPGAIGRGQTTATALNYFFQFFCYFTPILGAIVADQYLGKYKAIALFCGIYMVGLLVLVLTSIPTAILHGAALPGLVITMIVIGLGTGGIKANVSPMVAEQYQGNKTKVKTLKSGERVIVDPAVTVQSIFNWFYWSINLGSLSAIITTNVEKYYAFWLAYLIPLIVFNGAVIALWIGRNKVVKTPPRGSVLLEAFRAFGIALRNGRNLDAAKPSVIQTRSPQASMARITWDDIFIDELRLTLKACSIFCFYPFYWVIYNQITSNLTSQAGTMLLYGLPNDVVNNIDPIVLIIFIPIFDKIIYPGLRRIGLEPRPVLRICLGFFCAAIAMAWTAIVQHKIYITGPNYACTLCDPDQTPNNVSIAWQVPSYFFIAISEIFASITGLEFAFTNAPSSMKSVVMAIFLFMNCLGALLGFAFLPMTVDPLLLWMYTTLGCVALVISGIIYYFFRDYDKTMLADKMELQAKYDMRSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SW53</accession>
    <name>A0A9P6SW53_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Palmitoyltransferase</fullName>
            <ecNumber evidence="10">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BGZ80_004239</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="10">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the DHHC palmitoyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="10"/>
    <dbReference type="EMBL" id="JAAAID010002183">
        <property type="protein sequence ID" value="KAG0007775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SW53"/>
    <dbReference type="OrthoDB" id="9909019at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12246">
        <property type="entry name" value="PALMITOYLTRANSFERASE ZDHHC16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0564">Palmitate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="12">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="174"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="174"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="209"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0007775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="220" mass="25446" checksum="9C346FFB7D273E60" modified="2023-09-13" version="1">MDHHCPWILNCVGQDNYKFFVLFIAYTTLFCLFILISLIPLYVRYSDMTWTHELQVAGMVLTGIFGFTLVAFTISHIRLILLNRTTIEDHMTPMDEGPFPCVRKGWSQSEGEVNQGNERLYDLGFKENWEQTMGKGWKCIIPVRFPRPEGPIYNQKVVARQWQDYNRQLEAQKLQEQQEVPQQSEESIAAVTSMPSPTEHDVNRRPSISSTQLQTSSQLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWL7</accession>
    <name>A0A9P6SWL7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_003976</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002088">
        <property type="protein sequence ID" value="KAG0007993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWL7"/>
    <dbReference type="OrthoDB" id="73901at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040502956" evidence="3">
        <location>
            <begin position="20"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="250"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="219"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0007993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="268" mass="27372" checksum="0E45E08F621956D6" modified="2023-09-13" version="1">MRSSLFLAVTSALIASVWAHDGPHDTPTAPSVCLSAPTNATCSSFVIPSATITGAIGDICKASSFLPGCSLNTACSADSSLNATYCAPLTILATLCTATDDAALTNSTCGTTYNVFCSKDSLIPGCKSLPAFPGLPSGKAVTGAIYSVCQEMPMMTDCKICPAPDAKTGYSNCDEVKAWKGLCLDMPDMTQCPPFNTMCNSTKFAPFCNMDYKSPNNGTVTSPTNTTNTTNPSTPAGGNGKSGAGALADSMVMTSLVAIVAGVFALIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWN2</accession>
    <name>A0A9P6SWN2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Protein Aster-C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">GRAMD1C</name>
        <name evidence="9" type="ORF">BGZ80_003174</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the YSP2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001824">
        <property type="protein sequence ID" value="KAG0008681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWN2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032541">
        <property type="term" value="C:cortical endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140268">
        <property type="term" value="C:endoplasmic reticulum-plasma membrane contact site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032934">
        <property type="term" value="F:sterol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120015">
        <property type="term" value="F:sterol transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032366">
        <property type="term" value="P:intracellular sterol transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051482">
        <property type="entry name" value="Cholesterol_transport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004182">
        <property type="entry name" value="GRAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031968">
        <property type="entry name" value="VASt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23319">
        <property type="entry name" value="GRAM DOMAIN CONTAINING 1B, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23319:SF4">
        <property type="entry name" value="GRAM DOMAIN CONTAINING 1B, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02893">
        <property type="entry name" value="GRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16016">
        <property type="entry name" value="VASt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00568">
        <property type="entry name" value="GRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51778">
        <property type="entry name" value="VAST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="992"/>
            <end position="1012"/>
        </location>
    </feature>
    <feature type="domain" description="VASt" evidence="8">
        <location>
            <begin position="547"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="429"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="937"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="442"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1088"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0008681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1088" mass="119576" checksum="814244D1446A15E3" modified="2023-09-13" version="1" fragment="single">TDVKNTMPQLVQRAESSSFASTSTKPRRSTFSLALPWKPSANISNYAVSPQIPANHPASSNSQLKLSKSQRRFAASFPELADLLNTPQECCLSCLATPPHTPPDALRPAYPSDPSSSPPDTISAISSTERINSISMDEVCRGHLNDYICALERDNLYQGRLYVTVAHLCFYGEHSGKVVRIIINYNDIVSVEREVDLFSYSIRIRAKPLLHTVVASQNGAMSHEDLLTRKDYVLTSFVNYEQAVMEIERKWISVRQDGTSQLMESESFMAESMRLDRSRQECTLERRRLTRAQSLAERGTYSTSSIVSMLEASAHSLSSRHNGIISTVDDEKFIYSLGRTTSQFDGSMSASSLDLPVTYEFQNQRYFKSNRRPSEYHPASSPDHTFERAGAETPMILSNNTGDYDVSFNQTLAVPIPIQVSSSSSLRGYKFKSPTPPPSLLSPPLTTTKVSRSSSTVHGAAGKGTSPGMIVHVRTGSESADFDGNTGNKVDAPGKLASQNHFTSEELLPKLPHPSSQNGPRAFLSLTRPETTQDLSAPVLCGCERHCQNAILSTVVPIPLDLCFELLFSGQGAGQGDTLTCEAHRRVSGSSDVGITAWTADSLDDNVAGLSGWGKRKRQLEYSVLFKVPMLTKTSTACFETQEILQHSANIIRVQSESRIPNVPYGEQFSTLDQICMTWDSPGNTRIKCFTEVKFKRSIMLSSKVEAASLEVFGGFYRELIRQLVDVAETQSSMVVRAVLSALTSEALIRSPSISSDSATYSKVDDFSSSDLDAITPTSPSIYSRPSGVSAAQSLLSQQYLKSPPTISKHPRFSTSLTFTPAEFTLPGRTSRKITGLALRERRSTATDVLKSIDLLTPSPMETPVLRHQDSIENKGTVADSTTAKSVTKAIDLWTEFMSKGRAIFNKTNAHESHSKPATSEASRECAAACDDAELDPSTLESEPSVLGEPINVPKDKEGSTGLSEIEWAASDNMGSHRLEKPRTKPRLIPHIVIWTFAIGLIISILNAWRLVNTVSSVAHIMQTRNNQVDNAAESPLHNAFGSSVISRHLEKQAYLVPIQIQTEMLRAEIMELKELLEAQKKLHQLRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWQ6</accession>
    <name>A0A9P6SWQ6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_003057</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001789">
        <property type="protein sequence ID" value="KAG0008780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWQ6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050562">
        <property type="entry name" value="FAD_mOase_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356:SF2">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356">
        <property type="entry name" value="FAD-DEPENDENT MONOOXYGENASE ASQG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="53"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="484"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="262"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="406"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="271"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="406"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="421"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="436"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0008780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="905" mass="97481" checksum="94ACC30984BA9F9C" modified="2023-09-13" version="1">MSILSPSPLILSSIFHSSSSTSLSSLSSSSTTTAAQAFKSNFSLNPELAKPHIIIVGGGIGGLMLAILLEHGQIPYTVLERSTHIRLLGSAIALGPGVLPLFDQLGMLKEIEQFSRPVTRGMVWSEKLVPIMDLDHTTTQTRYGYLTRIISRPKLYEILLSRVPSGKLHLGKKVVSYKQELPSPLEQQQQPQQPSETKNIIVSCEDGSIFTGDILVGADGAHSVTRQLMYQYKEEDYAAFITAAKIASISLADDVINKKKKKSFNSNSEDSNSDSDSDSDQDPCIKTNNLNPNPEIPTDASCYSSCYTPLPDSDKEPLVFTSTCLVGQTRPGLDLKKFKYIRGPDCKIGSIVGDNKPYSWSIFSMPDDSICWMVTQHLGESFHVTPLGSSPSSPISDSAYYSNYTSESSSGSSSPTSKTSSKSKSKSKSKSKSRSKVSGNDSDSSSNSSNLGWGPDKVEMMCEQVKDFPIPCGPGLKLSDLIQETDHDRISKVMLEEKLFETWSCGRVVLIGDACHKMHPSAGLGAVAAIQDAAVLSDIIYHLPPSPSPQDLAQAFKTYYDDRYHMAKQSYETSYQMSHLNEQSWIGSFIRKVMSNLPKWIWYRVLDSMYEYRPQVSFLPKVEECGDVPAFSVASSNDGGGNDEDGVLIVDGSDGCCFKGGVSIVVLLCCASKDKDWVFVAVSVAAVTGAGAADISVRVLDKPAKDDNDLRGCDELGARFDNEERPLPLPAPVRGVSPTDGRFNPIAAVDAAGDNGVDLLVEDVAKLASGADPGEVAPVGAVAVADEEAKRVNPPGDLDNPPPVPVVDDDDPLARSRSEGVPVALFVSLRAPRLDKLGEPLPVLPPPPAAAARLERLCRGRVPEANVANEGVGVVAFDGVDCEFSDDCDALFEFLASPASRDIVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXD5</accession>
    <name>A0A9P6SXD5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_002348</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001575">
        <property type="protein sequence ID" value="KAG0009483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXD5"/>
    <dbReference type="OrthoDB" id="2128908at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0009483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="158" mass="18130" checksum="2736FC97A4305B1B" modified="2023-09-13" version="1">MIQIFLGLMLYVEPLYMIPRSKLNVSGTVKERVAVVVASNRPKNIEALKERIDFSPIIPSSLENDEMDLSGSSQDIIKKLYVEGLKKCDKVYCMILDDDVVFIYNDLKEVLFDNIISYNNDNNYVFDCSKKGFLRRLPTDVLGRLRREEVSVGSARRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXG1</accession>
    <name>A0A9P6SXG1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Flavin-containing monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_002219</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAD-binding monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001541">
        <property type="protein sequence ID" value="KAG0009621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXG1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004499">
        <property type="term" value="F:N,N-dimethylaniline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051209">
        <property type="entry name" value="FAD-bind_Monooxygenase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877:SF4">
        <property type="entry name" value="FAD_NAD(P)-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="393"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0009621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="412" mass="47694" checksum="5BCB041DB68E06B3" modified="2023-09-13" version="1">MFELQPDLGGTWLTSTYPGCQSDAPIHLYSYSFAPNYNFSKKFAPQSEILAYLQATAKTYNIYDKIRFRTRVSNVRWDESHNKWILHWINIDTEEEGIYEADVVFHATGVLRVPNIPKEFDAFKGDKWHSAKWNHSVDLTGKRVGVVDTTILLYQKMAWYSAFHRVVVYFVTWFYRFQQFPFNSELREKLTPKYELASRRIVLSDHFFSTLKMPHTSLHQSPITSINGNTIETSDGTKRELDVLILATGFDSSSNFPDGYWIGRGGIEIKKHWNGCPTVYCGIWVPHAPNFFLIWGPNSSTAHHAMTRVFEIQVMHAIRAISYMMEQNLVSMEIKQEVAEEFTNTIDQRMERSIFTTKMMPNLNFLLLANLSVQTMTIGFVIRAVLGTQGQEESAWQGSNQKRKSNNQFSYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXL6</accession>
    <name>A0A9P6SXL6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_001639</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001379">
        <property type="protein sequence ID" value="KAG0010258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXL6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044695">
        <property type="term" value="C:Dsc E3 ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045226">
        <property type="entry name" value="Dsc3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025390">
        <property type="entry name" value="Dsc3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28049:SF1">
        <property type="entry name" value="DSC E3 UBIQUITIN LIGASE COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28049">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN YOR223W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13373">
        <property type="entry name" value="Dsc3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="494"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="524"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-like" evidence="3">
        <location>
            <begin position="91"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="192"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="310"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="30"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="265"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="325"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="364"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="394"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0010258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="542" mass="58566" checksum="B08AE384B7EFF1F7" modified="2023-09-13" version="1">MSYARVNTSSDSEDDASSIPTSPSAHVRRTSSAAAASLASLTRSDSHRSHGYSQLSNNAIGEEDSTQNNVGEGAAAIDLQEQDKTDSENDIEIHLRFGEGQDLKLRVPRTDTIAQVKQAKESVGDKYMRLIHSGKILSDEKTLIESLPKSLFTQIEVPHPHHDFHDLQSRLSSSVEAVEAAASNILAGISSRASGGDKAIDNSQSNSRTQTSLGSILPTHVTYSSGSSNHTDNNTTPVTTSPTIPDPLSPEDNRNHISINMPTESPSISNNNPSSRGGKHQNARSASTIKIPVQTGPIYFLCSLSDFPPTQPPSSVKKGKAVVIGNNSGSGSTRPSRTARNRQHIPSQSASAAASSPLTLPGRNNVNSNGEGSSSSSARAMDGIPEEHYRAEGNEDEDDVQSEEELSPTMVPQATGFDRLREAGFSEDEIRSIRRQFHVSRGTMASSVGENGIAIELDQDEDSRARARRIEEEWIDQHGAETLPEGLEGSYGEMVWGLMLGFFMGLMALFWFKEATFSRRQQMGIIAGLMINIGFGCLHLYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXN5</accession>
    <name>A0A9P6SXN5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001599</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001367">
        <property type="protein sequence ID" value="KAG0010309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXN5"/>
    <dbReference type="OrthoDB" id="2433577at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="225"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="306"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="33"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="61"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="120"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="243"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0010309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="370" mass="39951" checksum="BED45C9F8C4D747E" modified="2023-09-13" version="1">MASIIPFPNVVTHRRMPHLPNSPKPTSIQHPNQEQQQQQKQQQQQNSQQPDYGLQGQVQDSTSSGLRLASGSSSTQRLFLEDGQGQLPHTSGAITGRTVQESERAHRSLHPEEHAQLHKSSSTASSPVMTSHDSKLIKTALYDAFGCLYHPSAHTKHSISNNAIALRSGDVTPLMGLSPKASPLLRPNLGPSAPITPLELSEEGSTAGYFALHVPASSALPAINTPMSGSTPTRHHTHQFRNTHTSSNLSSTFTSDSYEELEHAHQSPISLSRRSSMDVVLDPAEHPVLSSLQALSLSHDKLSFKDSSMTHLRSEPPSAQGSSGAVNPTDQSDASMQYTRALHTSPTSNFFSLDHNEHSSISGFGQQGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXW7</accession>
    <name>A0A9P6SXW7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Negative cofactor 2 transcription regulator complex subunit ncb2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">NCB2</name>
        <name evidence="5" type="ORF">BGZ80_001538</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001353">
        <property type="protein sequence ID" value="KAG0010374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXW7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017054">
        <property type="term" value="C:negative cofactor 2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017025">
        <property type="term" value="F:TBP-class protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051123">
        <property type="term" value="P:RNA polymerase II preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22905">
        <property type="entry name" value="HFD_Dr1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000019">
        <property type="entry name" value="Negative cofactor 2 beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003958">
        <property type="entry name" value="CBFA_NFYB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042225">
        <property type="entry name" value="Ncb2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46138">
        <property type="entry name" value="PROTEIN DR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46138:SF1">
        <property type="entry name" value="PROTEIN DR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00808">
        <property type="entry name" value="CBFD_NFYB_HMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transcription factor CBF/NF-Y/archaeal histone" evidence="4">
        <location>
            <begin position="3"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="85"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="85"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0010374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="130" mass="14789" checksum="D845C4A72E657574" modified="2023-09-13" version="1">MQPEATVQKLINEMMPDDIACAKDTRDLLIECCVEFIHLLASEANEICEKETKKTIAAEHVIAALKTLGFDGYLPEVEVVLQDHKTQQKVKDKDKKSGRLENSGKSVEELLEEQTRLFAEAKERHQTQQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXZ6</accession>
    <name>A0A9P6SXZ6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Prolyl 4-hydroxylase alpha subunit Fe(2+) 2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_001954</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001467">
        <property type="protein sequence ID" value="KAG0009898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXZ6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33099">
        <property type="entry name" value="FE2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33099:SF14">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT FE(2+) 2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0009898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="276" mass="30917" checksum="DA969F1BA1AC6DAC" modified="2023-09-13" version="1" fragment="single">MAKTVGLCSLYGENELSEGIAVLFGAKSLQFPVDADDVSKVSELVEACVPSGFGMNERTVVDPSYRNCKEMKPKSFTISNNYHEILPRIVAQVANALDSPKPIYASLNKICVYEMHGLFKEHVDIPKSNIFASLVVCLPTGYEGGKLIVEQDAYDLSSSTSIKWCAFYSDCKHRIEEVTKGFQVTLTYDLLYLDVPEPTPYRDALYKTLEKSLMKLYAKHDIDPALAADEEPKFVIGIPLTSKYPSLNRRHVRTSDENHPILKGMDLKMLTILHDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYD3</accession>
    <name>A0A9P6SYD3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_000778</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001170">
        <property type="protein sequence ID" value="KAG0011315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYD3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051061">
        <property type="entry name" value="Zinc_finger_trans_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46179:SF26">
        <property type="entry name" value="ZINC FINGER PROTEIN 423 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="372"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="406"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="439"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="258"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="468"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="12"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="258"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="491"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="511"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="543"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0011315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="568" mass="61321" checksum="18C5D695D8E52350" modified="2023-09-13" version="1" fragment="single">QQQPQQQPQQHKYPDLHPDLHPDLAGATISTSSPIVIPATNAPPLTLASSATPLPYQQGQSSYTNNSSAFSQVHNKNVSPATQLTPTSHHFETNLPLTFSSWAPDNEHNRQSHKQTRPFGVVDNVGYPAHEPPYPTGGSYMSGNGNIGNEKSRIQSSKQSSLTKNVMDYSNGYDARTQDSSLAAHHPGIASIEGLPLLSPSHLPYTDPQGQTFQPIVLNSGPGHKTMTTSLDSVPMGLGSPSIMPHPEYGAAASYLPTPQTLLPKSRPQSGSSRPLHNRAQSSGSPSTTNNAPRHRTRTASINSVSSISSSIITSLGSTNISFPDSPTPINTATGDMSDMTAYNSMSSPYPSINQKSRPSIHARKAVAARVFECAVPGCNKAYTQLHNLKSHERTGHTPIQKPKPFLCIIAGCTKAFSQRKSLALHIRASHKEYKFKPFKCSQPSCQKAYTQLHNLRTHEKTVHMLDLSRKRIRNPAPNPGNGDGVSMTEGPGNDDSGNSDSNQDPGQIPLSGQTNQKSQLTSGEESSYGSADNLASYNVGMDDNEEEEGEDAEDEDEDENDVDYVDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYR6</accession>
    <name>A0A9P6SYR6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NAD-specific glutamate dehydrogenase</fullName>
            <ecNumber evidence="4">1.4.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">GDH2_2</name>
        <name evidence="6" type="ORF">BGZ80_000382</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">NAD(+)-dependent glutamate dehydrogenase which degrades glutamate to ammonia and alpha-ketoglutarate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>L-glutamate + NAD(+) + H2O = 2-oxoglutarate + NH4(+) + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15133"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.4.1.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the Glu/Leu/Phe/Val dehydrogenases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.1.2" evidence="4"/>
    <dbReference type="EMBL" id="JAAAID010001078">
        <property type="protein sequence ID" value="KAG0011843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYR6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004352">
        <property type="term" value="F:glutamate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006538">
        <property type="term" value="P:L-glutamate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006096">
        <property type="entry name" value="Glu/Leu/Phe/Val/Trp_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056365">
        <property type="entry name" value="NAD-GDH_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016210">
        <property type="entry name" value="NAD-GDH_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055480">
        <property type="entry name" value="NAD-GDH_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11606">
        <property type="entry name" value="GLUTAMATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11606:SF24">
        <property type="entry name" value="NAD-SPECIFIC GLUTAMATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00208">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23147">
        <property type="entry name" value="GDH2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23152">
        <property type="entry name" value="GDH_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000184">
        <property type="entry name" value="GDH_NAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00839">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0520">NAD</keyword>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal" evidence="5">
        <location>
            <begin position="626"/>
            <end position="890"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR000184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0011843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="991" mass="112662" checksum="E696B68E8068DA70" modified="2023-09-13" version="1">MTAANVDVAAQNGQGHTLKNMPGYIENAFSGKSAQMVQVTEYLSEKGFIPTALAQNEVSWFYGNLGIDDMYFASESVESIANHIMALYGAKIFAYTKNDNGLDINLERETEEGAVYIHTSRPGVSQLYGPQHEKRIDSKYLDVSNVERAFRLESYRSKGTVSSSSSTQLRTYFVRQCSFVNPTPTKEQETDIRETADKSFLEKATENTLEIYSTVMKQALGRTGPVIEMFEVEGSRERRLYVEQFSNGITIVSLYLNQIPKSTAPPIEHSIHQIIKEASLIYCLPTTPLQSFFQTNKLSVQESIYGYIGWIFAQHFLNRLGNEYVSLVNILDTTNSTHQDVLTKMKKRLRTDTFTRDYILEIIKTYPELVKLLYINFAMIHYVNPAVNSLQPTLSYQRLRTDTVLTEEELYEKIRRTTSNSHELMVFESFLIFNKHVLKTNFYQPTKVALSFRMDPSFLPEIEYPTKLFGMFLVIGSEFRGFHLRFRDVARGGIRIIRSRNREAYSINLRSLFDENYALANTQQRKNKDIPEGGSKGTILLDVNQQDKALVAFEKYVDAVLDLLILGETPGIKERIVDLYKKPEILFFGPDEGTADYMDWASAHARERGASFWKAFTTGKSQSLGGIPHDTYGMTTRSVHQYVLGIYRKLGLKEENCHKLQTGGPDGDLGSNEIKISTDKTCGVVDGSGVLYDPEGIDRTELGRLAGSRLMISNFDVSKLSPKGFRVLVDEVNVKLPSGEVIDDGLSFRNNFHLNPMVNCEVFVPCGGRPESVDLQNVSRLLDAENHPRFKYIVEGANLFFTQEARLRLERAGAIVFKDASANKGGVTSSSLEVLAALAFTDEEFAEHMQVTPDHTPVFYQEYVKEVQTIIERNAHLEFEALWREHQRTRTPRSILSDDLSLAIVKLNENLQHTSLWDNVALRKVVLEEAFPNMLLKQVGLDKLMERVPENYVRAIFGSYLASRFVYKYGTEPNQFAFFEFMTPYFSKVQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYW4</accession>
    <name>A0A9P6SYW4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="14">General negative regulator of transcription subunit 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">NOT5</name>
        <name evidence="14" type="ORF">BGZ80_011761</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CNOT2/3/5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000989">
        <property type="protein sequence ID" value="KAG0012402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYW4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030015">
        <property type="term" value="C:CCR4-NOT core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000289">
        <property type="term" value="P:nuclear-transcribed mRNA poly(A) tail shortening"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.1020">
        <property type="entry name" value="CCR4-NOT complex subunit 2/3/5, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038635">
        <property type="entry name" value="CCR4-NOT_su2/3/5_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012270">
        <property type="entry name" value="CCR4-NOT_su3/5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040168">
        <property type="entry name" value="Not2/3/5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007282">
        <property type="entry name" value="NOT2/3/5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007207">
        <property type="entry name" value="Not_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23326">
        <property type="entry name" value="CCR4 NOT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04153">
        <property type="entry name" value="NOT2_3_5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04065">
        <property type="entry name" value="Not3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005290">
        <property type="entry name" value="NOT_su_3_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0678">Repressor</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="CCR4-Not complex component Not N-terminal" evidence="12">
        <location>
            <begin position="1"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="NOT2/NOT3/NOT5 C-terminal" evidence="13">
        <location>
            <begin position="515"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="236"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="337"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="29"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="123"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="236"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="290"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="310"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="337"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="365"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="399"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="446"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF04065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0012402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="635" mass="70746" checksum="970DBE7E251CAA2F" modified="2023-09-13" version="1" fragment="single">EIDKVLKKVAEGVETFEETLDKIETSTNANQKEKYESDLKKEIKKLQRLRDQIKTWISSNDIKDKRALTDNRKLIEQQMEKFKAIEKEMKTKAYSREGLIMSGRLDPKEKEKAETCAWVTDRVEALSIQIEGMEAEVETLQASAKKGKNNPAKERVAVLEEKIERHKWHQGRLELILRLLENGQIDTDKVLAVQEDVNYYVDENSNPDFAEDEEIYTDLNLSDEEDYFTVGMEDHTHENDERQEQDSPVPAPTPKKQIKEPELEPSPPKATAKSILTKKPSMAEPKETKTITAASPASTKSTPNIPPSRQPTIPRSGSADSPVIQYATAVAANLPAEPARALSSASPSVAAAVLAKDSPKPDNASIKSESPSSLATTLTTVAPSNHGSDPAPIPSPSLSQAKASPSVAPASSSSLTEESRSAPPAEVSSSTVEPSPATPIQAIQEAASQNEATSTQSIKSQSTVPTAGTPVAPAEPEIRLPAALADLAHSFETSKERALMKEVGFFAQQMLETSYQFIPEAADTERPKYYTPKNPYPTPPYYPQSPPPGLFESPAMFEKFDIDTLYLAARELKKQSWRFHKKYLTWFQRHEEPKAITDDYEQGTYIYFDYEGAWCQRKKTDFRFEYKFLEDSELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZ02</accession>
    <name>A0A9P6SZ02_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_011498</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000930">
        <property type="protein sequence ID" value="KAG0012816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZ02"/>
    <dbReference type="OrthoDB" id="2449814at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="434"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="443"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0012816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="545" mass="59319" checksum="6D4B9A2141F2919D" modified="2023-09-13" version="1">MPLAAISHACSQSSNAKHPKSSLQHPKSPLQHPPSPSVLASSLQTVRYAGEQGKLLAQKSYSSLNRLLDSVMDNATALTESGSRQMYHHSSGDSHIFLTNSPSTKGSKASTITPTSTPLKRPSLARNHSSKATFFVCEDDSEDEEDEEEDEEDEEDGLKQENQRPKVPHFIKVRSSMEFIDYCRGDFQAFERLGDNEDIDQEDYFRKAALFKHDRTPIHTSVSGPLSDAPGMGRRQSLLSDLFMTEKLLAAQRASSCKAVNNNTTIWARPPLYPDPPLSRHSAISPEGDDLFSAVVDPQQIIRLTQLKAQPTCQTLVGLAHQSIQSSHHQHQHFDDRIPIQEELVSPKVMAGHEMTPKSPLKRTRKSMFKNLDELAIDTTTDGQEADDTEHFILQSQQPDLTPANLAAATAPTYEIPDCKTAFVTISPAFIPAPASPSPSPPKSSKNLPPHSTLSSPAKACRCSPATATTKTAFATVSATSKCTATTSPVFSAVTAAAAIAANTGIGGDNFSSWTQVYHFQAHIQSFYEHLSSSIQKAISTSSET</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZI7</accession>
    <name>A0A9P6SZI7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphoenolpyruvate carboxykinase (ATP)</fullName>
            <ecNumber evidence="3">4.1.1.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">PCK1_5</name>
        <name evidence="12" type="ORF">BGZ80_010759</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>oxaloacetate + ATP = phosphoenolpyruvate + ADP + CO2</text>
            <dbReference type="Rhea" id="RHEA:18617"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.1.1.49"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.49" evidence="3"/>
    <dbReference type="EMBL" id="JAAAID010000785">
        <property type="protein sequence ID" value="KAG0013937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZI7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004612">
        <property type="term" value="F:phosphoenolpyruvate carboxykinase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.449.10:FF:000002">
        <property type="entry name" value="Phosphoenolpyruvate carboxykinase [ATP]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.228.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.449.10">
        <property type="entry name" value="Phosphoenolpyruvate Carboxykinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00453">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001272">
        <property type="entry name" value="PEP_carboxykinase_ATP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013035">
        <property type="entry name" value="PEP_carboxykinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008210">
        <property type="entry name" value="PEP_carboxykinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015994">
        <property type="entry name" value="PEPCK_ATP_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00224">
        <property type="entry name" value="pckA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30031:SF0">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYKINASE (ATP)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30031">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYKINASE ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01293">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006294">
        <property type="entry name" value="PEP_crbxkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68923">
        <property type="entry name" value="PEP carboxykinase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53795">
        <property type="entry name" value="PEP carboxykinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00532">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="5" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="12" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="14"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="29"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0013937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="445" mass="49366" checksum="52EB56C68CD0ECC9" modified="2023-09-13" version="1" fragment="single">MSSHHLQVEELKSKSSASSIHSQSSHQSNTGSHAHNSHYPQQSHPGIHHKAYHPDPETMYHDTGIDYNHVLMNRNASVAKLYEDALKYEDGSIISSAGALVTSSGKKTGRSPKDKRIVDEPSTSDDIWWGPVNTKLSEHGFLINHERAVDYLNTRERLYVFDGYAGWDPKYRIKIRVVCARAYHCLFMRNMLIRPTDEELEEYGEPDFTILNAGAFPANRYTTGMTSNTSVSINFRRREMVILGTEYAGEMKKGVFTIMHYLMPKAGVLSLHSSANQGEKGDVTVFFGLSGTGKTTLSADPRRHLIGDDEHCWSDTGVFNIEGGCYAKCIDLSAEKEPEIFGAIRFGSVLENVVLDEDTRTVDYNDCSLTENTRCAYPIEYIPNALIPCVSSSHPSNIIMLTCDAFGVLPPVSKLSSAQAMYHFISGFTAKMAGTEDGVTEPEAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZS7</accession>
    <name>A0A9P6SZS7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_010751</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000784">
        <property type="protein sequence ID" value="KAG0013947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZS7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0013947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="105" mass="12165" checksum="C7DD9C1F70E2238C" modified="2023-09-13" version="1">MPGPRLAPEGNTSLFGATYLAFFSETQLRYGSLCQGNKKKKELLQEAAFAFKEYNIRGRKVDLLFQTVYKNHKDKENLRLNKTLLANLRRMDVMSFPDFLIKTTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0Z7</accession>
    <name>A0A9P6T0Z7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">LYR motif-containing protein 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">LYRM5</name>
        <name evidence="3" type="ORF">BGZ80_009077</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the complex I LYR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000517">
        <property type="protein sequence ID" value="KAG0016620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0Z7"/>
    <dbReference type="OrthoDB" id="10258445at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090324">
        <property type="term" value="P:negative regulation of oxidative phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20265">
        <property type="entry name" value="Complex1_LYR_ETFRF1_LYRM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008011">
        <property type="entry name" value="Complex1_LYR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045296">
        <property type="entry name" value="Complex1_LYR_ETFRF1_LYRM5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052000">
        <property type="entry name" value="ETFRF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21024:SF0">
        <property type="entry name" value="ELECTRON TRANSFER FLAVOPROTEIN REGULATORY FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21024">
        <property type="entry name" value="GROWTH HORMONE-INDUCIBLE SOLUBLE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05347">
        <property type="entry name" value="Complex1_LYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Complex 1 LYR protein" evidence="2">
        <location>
            <begin position="7"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0016620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="105" mass="12442" checksum="A1AB70CFE38CF46F" modified="2023-09-13" version="1">MSSPSRQRVIALYKQLSYLGREYPAGADYFHKKLKSAFLKNKDLSDPVEIQKRIDLGDYVCKEIEAMYHINKYRAMKKRYYEETQVENIQSKLENTNWADGTVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T167</accession>
    <name>A0A9P6T167_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_008257</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000442">
        <property type="protein sequence ID" value="KAG0017468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T167"/>
    <dbReference type="OrthoDB" id="2130629at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY MULTIDRUG TRANSPORTER MFSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42718:SF9">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY MULTIDRUG TRANSPORTER MFSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="49"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="116"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="174"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="208"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="240"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="277"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="310"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="341"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="366"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="406"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="453"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="50"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="496"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="513"/>
            <end position="528"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0017468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="547" mass="59546" checksum="4E1544E24B583BC3" modified="2023-09-13" version="1">MSDSETATVTSVSIPSHNPPATTTSSYPITTDPVKKLVWYRRLREIKGLLLFLISMAAMLDIINVASITIALPSILRDVGYDTNNLQWCVSAYALTYAAFLLIGGRMGDLFGHKRIFLLGTSWFAIWALVCGFARNAVFMSVARALEGAGAGFTIQTIGVLLGGIFDATIGWQWIFYLTAIISATLSIAGFFIISGHEEKPSTVDNRIDYGGALSFTIGIVAIIYYLTESTTAGWSSSKTLPPLFVGIAFLIGFVILESKIDYPIMPFHIWKSRRFLSSIIIIICLTATYNTMIFYSSLTFQNVLHYDSLITACCYIVHGVGLIIGLYTVTKLFILTRTKVIMFVGWCFVIGSSIIFAQIRPDSTYWHYAFPAFIINCMGLSPTWMCCQVNAVADAKDEDQGIVGAIFNVGVQLGAPIGLAIANIIAEAYTPDTLVDGATSVSDENLMKGYSAAFYAYGVMGGVGLVMMLIFAANRDPAEFSEVAKAPAKELSDLEQYELGGDKEEVLDESIEGEKEVGEEAGQKTDMDSNSSIASLDRTAIPTKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1G8</accession>
    <name>A0A9P6T1G8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_008010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000422">
        <property type="protein sequence ID" value="KAG0017695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1G8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0017695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="590" mass="66578" checksum="32C3289B7B587D30" modified="2023-09-13" version="1">MSTNSSDLTSCSKVFALPEICERISYSIDNKTITSCLRVNREWNASWLPILWHTIDAGHQWHNPAFVNALGEHGDLVRILKCTRYDDISPLLRTDKTICRNLVTIVLPKTTLVNQSDHIQLLRQNPHIRDLSLGLHDDNASLYTELVNAVGELRNLRRLALDENKILDVNTLETILSKCNGSLRELSLKGTYFIKHPFGSGNGFASGFLACSKSESQLGTELITNDVEIDSKETFGIMSLCLEGVVCTQDLILNLASRFPLLSHLSLKGSMEVYFSKNFPERLAKRCPKIKNIDISSTEDIDDDTIASLVGSFPGLQTFRASETRFGNESFSTLVEHCRDLTVLEINSTCQIQGQVIQQLFEKCWALRSLDAWDVSANVVEMMMEVYGGGKTVGATDAKNRVTVDGSITQTESSLKNIRGQWVCRGIERLVLRFDYDPSELSEESEQLYPASRARRFIYEQLSKLTKLKYLAIGGTLSTTWQMCGRGDETDEKDNSTLDDQPTFDISDDIWIDFSLRSGLFLLSPLKELRTLCLSAMDHAIGLPEIIWISENWPNLKSIEGLYEDDDEDVVNWLRENRPDIEIRNEDDGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2E1</accession>
    <name>A0A9P6T2E1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">NAD-dependent protein lipoamidase sirtuin-4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">SIRT4</name>
        <name evidence="7" type="ORF">BGZ80_005088</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sirtuin family. Class I subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000253">
        <property type="protein sequence ID" value="KAG0019905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2E1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017136">
        <property type="term" value="F:histone deacetylase activity, NAD-dependent"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1600.10">
        <property type="entry name" value="SIR2/SIRT2 'Small Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050134">
        <property type="entry name" value="NAD-dep_sirtuin_deacylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003000">
        <property type="entry name" value="Sirtuin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026591">
        <property type="entry name" value="Sirtuin_cat_small_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085:SF10">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02146">
        <property type="entry name" value="SIR2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="6">
        <location>
            <begin position="24"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="142"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="151"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="204"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="215"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="285"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="288"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0019905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="402" mass="44049" checksum="B7482DCF420C1043" modified="2023-09-13" version="1">MRLRISLSSVSKALSTSTTNSSPKPPFSIAVNELASFLRDGRPNITVLTGAGVSTDSAIPDYRGENGTYTLNPGYKPIFYQAFVASDEARQRYWARSFLGFPPVMTTQPNPTHYALTLLQSSSLSSSSPSNLSGQVQDQYQNLNQGQDNDPVQVQPQAQTQAQAQAQAQDSNRAQLGGYIRTLITQNVDGLHQKAGTKNVVELHGTLHRVKCMSCGHEEDRSEFQKVLADMNPEWNELIQSQSASSLYTRMNADGDVELKSPEQQQQTRPNDKQLDYRTFHYPKCSCCGSGDYKPSVVFFGENVPPGIKDSTTQAILEADALLVVGTSLTTFSAFRLVKLAKDVGVPIAMINLGKSRGDSLVDLRYEEPSTRLLKAVVSELGLGKVPGEIRRRKRTINVVGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-10-08" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2U0</accession>
    <name>A0A9P6T2U0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_003617</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000197">
        <property type="protein sequence ID" value="KAG0020777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.80">
        <property type="entry name" value="E3 ubiquitin-protein ligase SopA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056251">
        <property type="entry name" value="Arm_rpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879:SF9">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23948">
        <property type="entry name" value="ARM_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05729">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141571">
        <property type="entry name" value="Pentapeptide repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Arm-like repeat" evidence="5">
        <location>
            <begin position="235"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="domain" description="NACHT" evidence="4">
        <location>
            <begin position="731"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1269"/>
            <end position="1310"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1311"/>
            <end position="1352"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1353"/>
            <end position="1380"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1379"/>
            <end position="1420"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1421"/>
            <end position="1462"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1470"/>
            <end position="1504"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1505"/>
            <end position="1535"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1558"/>
            <end position="1599"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1600"/>
            <end position="1641"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1642"/>
            <end position="1683"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1684"/>
            <end position="1719"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF23948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0020777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1774" mass="196496" checksum="3C58442796DB9F0B" modified="2023-09-13" version="1">MLGKHRTGEDRSDFLSVPTHEGEATVEKITMFRKVFSSPSRDLPLNNTLELANEQIENARNASTPEKARWICNDAKTTIKDAGIIFTNRRVGGQTLNEDIADAYHKLGKVQEELGQHSEAQKSFKKATKWGYIEAVTQQTGTPQLANSRGSIGRSLLPRVALLATPSITAAMDMLDINDASSSHQGTLSGIKEQMPLARATHGGAELGAHMIFNRNASPPAVRSVLLEPGTRISSTSQLACCLSLMNHSLIPREGFETSEYLWAYVKIDDPDEQNRLRGMATDMVRAFIRDELKKPDVVVEIICLTAVLEQDDFRKLLQAFVDGINNSLLLEIHLLDGLSNLIRNSPQGALNADDLVKILELLGTRLKSTHQQSIQHTHRLALTVSSVLDSMVEGIARELLHEPLSEYLRGLQQSPDPCLVYQAAYAYQALQYIPDDETFLQTMLRRTGKVVQGIFGVVSAVKALDLNSFIEGLDHIQKGLPGAIQTIGLIGDAYENVTTLEGSGHGLYDSLKEGLGFTRKSAWYPALRGLDALVQEGRFTEFERLIREAPCRKDAAFQWGVCQRLGDLASSIVWDIDIRQHAASLLRDIYTDDSRWGNQASVKQWILHILRKLVESSEDTVADHAQRLLLDLKAEGDSKKRALYLACMKEDHSPFLMMVALPPPQGSRLLDIVQNKTDVETPLRQLKQERLTERGGDIYISPRAKIHPSATEDFDLTSHVEKFLTSDKKVFLLLGDSGAGKSTFNRSLEISLWDKYDKINGRIPLLVHLPAIEHPEVDLIDKQLRRLNFTQSQIRELKLHHQLILVCDGYDESQQTRNLYTSNQLNQPGQWQVQMVISCRTEYTGVDYKDCFRPTDRNGGGALNTFQEAAITPFNKNQIQDYVEQYVRLRNPSWESKDYLQALKQIPNSQDLMMNPFLLKLSLEVLPNLVNTKVDYSQTRVTRVELYDGFVQQWIERGKIRLGEMKLSSRDKEAFKILLSSITYLKKLAAAMHDNQTGNPVVNYSELGDQEAWKRTFFDNSNGNNLLREAIPLTRNNDQYQFIHKSVLEYGLALAVFDPNSCNENLEPPSTLSRRRSAGSIESFEDMSSVENQAVIIEQPLLDSIFGRKNFVDQASVLQFLVERVQQNAVFKQQLLAVIDRSKSEKNVRVAAANAITVLVRAGVQFIGSDLRGIQIPGADLSNGMFDSAQLDGADLRKVNICNIWLHNASLCGSRMKGVQFGELPLLQEESDVWSCAYSHDGKLLAVGLENSDINLYDTSTWEKIQTLRAHSDTVRCLAFSKAGGHIVSCSDDKSVRLWDVGTGNCVGTLLDHSDNVHSVAFSPNGDRIVSGSKDETVRLWEIESGSCILTLTGHGKIVLSVAYSPNGDQIASGSRDHTGHVHAVMSVAFSPNGDQIASGSADSTVRLWNVETGSCTQTLQGHSQAILGIAYSPSGNQVASGSIDRTMRLWNIQSRKSVHTKQEDDLYITSVGFSPNGDWIVSGGFDKTVHLWSVETGIRTRALLGHNNFVFSVAYSPDGSLIASGSEDRTLRVVSGGVDRIVRLWGVESGSCVNFFEGHSGNVNSVAYSPNGNQIASGGSDMTVKLWDIETSNCIHILEGHDRSVNCVAYSPNCSRIASGSSDGTIRLWDVDKGDCIHTLSGHKNEIVSVTYSPNGDVIASGSADNTVRLWDSESGKFLIAISGFSGPVMGVAWRDTLKGQYLATGSFDRSVRYWQIIKEQDEYKVHLHWTSSRGAFTLADASFIDVQGLSQTDLKLLNQRKALTTSPSPIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2W6</accession>
    <name>A0A9P6T2W6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_003338</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000188">
        <property type="protein sequence ID" value="KAG0020922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2W6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="116"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="404"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="513"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="711"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="13"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="478"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="119"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="159"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="410"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="426"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="523"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="561"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="711"/>
            <end position="728"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0020922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="872" mass="96024" checksum="EAF7DC90226261AE" modified="2023-09-13" version="1">MSVPIMDPFYRDLQALQSDHSSLLSKLKQMQQMLQGSYQELTMAQQRSKRAETDSRRLRAQMDIILKKHVDHHPERESLVQQLSELQSRLDLELGSRKALEREYSALHQEFLRHKLNNATTPTTGLSTPTVTATSPSSPSISVRSLPFSSFLRGGRSAYQKSNRNSSESEQSPSVKNLRFTENNEEVLSPQEQQQVPPTPASSHHHQQQKQEEDDGDGEKTKSSYEQDQETISTQLQFEAQKRKQFSVSQSEIELLRSTIHEQYLCLNARESLVQTFAATVNSQAVDIEILTNQSCRDQAALAKVEQELALLFEASLMMLERWFGNVQQTKEKLERCMDPIRQTILQFGCSNATQEWEKFEVGVRGLVDGLARSLMKQQAAQDSELETGVVNTNYYNTKAYHRERPLGGHTSSSYSNTSMKATFGNDNNNNNSNALYNSNYSNGEDGEMAIETTPLVFDNTRSQEVFVWRKFTADTFLENCVKSVENLAQERRKLQIRLAELTQLLADQEERRGRCLGSGGDNNEKTKESSENLQQEKSEKNEPEKADNEDRSVGAEEHQTTTTATTATTATDSAKRADQLEAILKRVLEWGDRCHSPSNPKNASKTVATLGDLEDEMLPLGISNGVLLGDSLKQQPLPQSQALNAMRAEVDTTANDSISHHQNLETLLQWVRQQMASSDGVPFKSSAATQVEPETTVAAMLTDAKENSLSSSLNSLNSGSSIDNNGGAARPKIRPEAITTSLSIGYSSATPSPNSSCYTAPPSASSCSSTSSYFPNRVNIGGLAMPKLSPGLGGLGPDGKASILDMDAFCSDLAFRSFPKQHQWSKSRGGASKGVTTLLQTWSPISTTTTGTAATAAAAVPPLQPTLVPST</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T308</accession>
    <name>A0A9P6T308_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Tyrosine--tRNA ligase</fullName>
            <ecNumber evidence="15">6.1.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Tyrosyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BGZ80_002936</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>tRNA(Tyr) + L-tyrosine + ATP = L-tyrosyl-tRNA(Tyr) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10220"/>
            <dbReference type="Rhea" id="RHEA-COMP:9706"/>
            <dbReference type="Rhea" id="RHEA-COMP:9707"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78536"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.1"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:10221"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.1" evidence="15"/>
    <dbReference type="EMBL" id="JAAAID010000175">
        <property type="protein sequence ID" value="KAG0021174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T308"/>
    <dbReference type="OrthoDB" id="197206at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004831">
        <property type="term" value="F:tyrosine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006437">
        <property type="term" value="P:tyrosyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02799">
        <property type="entry name" value="tRNA_bind_EMAP-II_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00805">
        <property type="entry name" value="TyrRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.240.10:FF:000004">
        <property type="entry name" value="Tyrosine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000040">
        <property type="entry name" value="Tyrosine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.240.10">
        <property type="entry name" value="Tyrosyl-Transfer RNA Synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002547">
        <property type="entry name" value="tRNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002307">
        <property type="entry name" value="Tyr-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050489">
        <property type="entry name" value="Tyr-tRNA_synthase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006330">
        <property type="entry name" value="PRK08560.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00234">
        <property type="entry name" value="tyrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46264:SF4">
        <property type="entry name" value="TYROSINE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46264">
        <property type="entry name" value="TYROSINE-TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01588">
        <property type="entry name" value="tRNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01040">
        <property type="entry name" value="TRNASYNTHTYR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50886">
        <property type="entry name" value="TRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 15" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="8 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 15" id="KW-0436">Ligase</keyword>
    <keyword evidence="7 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10 15" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 14" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 14" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="TRNA-binding" evidence="16">
        <location>
            <begin position="370"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU361234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0021174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="535" mass="58742" checksum="8B2DB1B09A29560E" modified="2023-09-13" version="1">MASLTPAEKYSIISRNLQEVLGKEQIETILAERDLNIYWGTAPTGKPHLGYFVPMTKIADFLEAGCHITILIADIHAFLDNMKAPMELVGKRAEYYTELIKATLTSIGVPIDKLKFVLGSSYQLTAEYSLANMKMCSKTTEHDAKKAGAEVVKQVANPLLSGLMYPGMQALDEEFLGVDAQFGGVDQRKIFVLAEKMLPALGYKKRSHLMNTMVPGLAGPKMSSSDPDSKIDLLEAPQDVKRKLGRAFCEEGNIAENGVLAFVKTVLFPLRSMNGKSPVFTILRPEKFGGDVTYTTYEALEEDFKEKKVHPGDLKNAVADAINELLGPIRKWFDNDKLRQLTEDAYPTPKPEVKAVKSNKPAANANLPVDISRVDIRVARIVEAKVHEANPNSYVSTVDCGNGDVRTVVSGLAKYVPLEEMQNRLVCAVCNLKPGKFQGILSSAMLLAGSNADDSVIELLQPPAGLEAGDLIEFEGYGQVDRSSPEKLNPKHLIFEKVSADFKISPDGHALYKELQFKTKAGPVTLKSLKEGRIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T390</accession>
    <name>A0A9P6T390_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_001930</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000146">
        <property type="protein sequence ID" value="KAG0021671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T390"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0021671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="74" mass="8549" checksum="8F50DE58499B6482" modified="2023-09-13" version="1">MLRTTTTAAVRAFKPVQFSVVARRNYTDKFKEKETAEEAKYIRTKEAEREKALKEKALKEKLAKEEAEKKAGTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3A9</accession>
    <name>A0A9P6T3A9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transcription initiation factor TFIID subunit 8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_003671</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAF8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000199">
        <property type="protein sequence ID" value="KAG0020738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3A9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08049">
        <property type="entry name" value="TAF8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037818">
        <property type="entry name" value="TAF8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019473">
        <property type="entry name" value="TFIID_su8_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46469">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46469:SF1">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10406">
        <property type="entry name" value="TAF8_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Transcription factor TFIID subunit 8 C-terminal" evidence="8">
        <location>
            <begin position="104"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="71"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="243"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="75"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="244"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF10406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0020738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="307" mass="34424" checksum="FC6175A807E0FDC2" modified="2023-09-13" version="1">MYSIAHSFSELAGRTKPNIHDLQQAFTDMNVSPASLESYVRSASRSKTPLLRGPLQETLAKVQKKKEKNVKLLDSDIEDNSESDDDEPATTSTPGNKVTARTIVPDHLPPFPSKHSYKQTPVFVKRPDDPQRIRELNAEQSRLVESNLKRLMAAENKIAMAAAHKDGSTAAVATDLLIVKEEQESAESIDRRALTKLEALPVVNYEFSKRQQQMSASNREGGRRQHQIQLHELQGEPLNSALNGGSGAGSGGGVSIYKSEWRKERRRMRKEQRNAMEELEQNINHKRLRQESVHSAQLKLVSMDIDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3K5</accession>
    <name>A0A9P6T3K5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">CCA tRNA nucleotidyltransferase, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">CCA1_1</name>
        <name evidence="7" type="ORF">BGZ80_002868</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000173">
        <property type="protein sequence ID" value="KAG0021205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3K5"/>
    <dbReference type="OrthoDB" id="445712at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052929">
        <property type="term" value="F:ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052927">
        <property type="term" value="F:CC tRNA cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001680">
        <property type="term" value="P:tRNA 3'-terminal CCA addition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05398">
        <property type="entry name" value="NT_ClassII-CCAase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3090.10">
        <property type="entry name" value="cca-adding enzyme, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002646">
        <property type="entry name" value="PolA_pol_head_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13734:SF5">
        <property type="entry name" value="CCA TRNA NUCLEOTIDYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13734">
        <property type="entry name" value="TRNA-NUCLEOTIDYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01743">
        <property type="entry name" value="PolyA_pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81891">
        <property type="entry name" value="Poly A polymerase C-terminal region-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Poly A polymerase head" evidence="6">
        <location>
            <begin position="33"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="304"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="455"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="307"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="461"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0021205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="586" mass="66632" checksum="49FB24025F6EF81B" modified="2023-09-13" version="1">MSIHLTRKETAIFRILDRVSKDYEAMTGQRMHLRVAGGWVRDKLLGLESKDIDIAVDKMLGHEFAALVKEDMASRDVKTKPIVRIAVNPEKSKHLETAIMNIMGVSIDFANLRSDVFDDSNRFSNDHVFGTPYEDAHYRDFTINALFYNIRNNSIEDYTGRGLDDLKNGLIRTPLNAIETFWQDPLRVLRCIRFAGRFQFKIANDAMDAMQEPKIREALKSKVSKERIGIEIVKILEDNVARPTAIRLLRQLNLYDLVFTYPTTSVLAKGTSDVFGERGDVEDAFKLAWIMEWLLKINPITPQVKTSDTRSSEKSISSDRGIPPEKSVSPFKPERDASQEQLLEQTQGHPMTSHLHALVTTERPEEAYAISGMEGIFESSNVTRRLILSSLLYPYYGVITTTNGKVVSGAVWICRYRLKVRLHDIEFIGTLQYNLEKVKQIVKSLNKDMALTEAEIEEEQQQQQQQQQEQQQQENHISEASSHSTDLTSSTTKHQEGSRTSSMGNLIKRIGSTLPTGKDWPSMFLFGLGVELLPNYEQLKQGVLDDDAKAKIAKYNTFLSKAEAYGIEHCYAWRHLVTIMGPSDYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3S4</accession>
    <name>A0A9P6T3S4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_011144</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000086">
        <property type="protein sequence ID" value="KAG0022795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3S4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF284">
        <property type="entry name" value="EG:103B4.3 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="15"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="79"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="151"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="186"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="216"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="240"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="276"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="310"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="4">
        <location>
            <begin position="150"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0022795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="344" mass="37136" checksum="C6BD72B537907B39" modified="2023-09-13" version="1">MTLSLILASFSKQIWQLYITQGVLFGIGASLAYYPAIAVPSHHFTKKLGLATGIAVSGVGAGGLILAPLTHTLIDKIDIYWTLRTLALVCLVVCGTASALIVEDKDRVDIIQSQSEKSDDKKYKERKLDEKGSEDKPSFFAALKVFKDPRFLFLSLAEFIVDLAFLVPLYYMQTYAVFIGLSAERGALILGFSNGASFAGRVILGLISDYFSNAKVLLVCAWFTAFAVLVLWSISHSFGMLLLMGLVYGFFIGGYISLVPVAVAQSFGAKQMASTMGLMFTAAGLAMFGGAPLAGFLLDVTQPNTSYLPVILASGLAVTLGALCVSIWAYLDWKVKRAQLVKDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3Z9</accession>
    <name>A0A9P6T3Z9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Enhancer of mRNA-decapping protein 4 WD40 repeat region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_009269</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">P-body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat EDC4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000054">
        <property type="protein sequence ID" value="KAG0023494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031087">
        <property type="term" value="P:deadenylation-independent decapping of nuclear-transcribed mRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.100">
        <property type="entry name" value="conserved c-terminal region of ge- 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045152">
        <property type="entry name" value="EDC4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049404">
        <property type="entry name" value="EDC4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044938">
        <property type="entry name" value="EDC4_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032401">
        <property type="entry name" value="EDC4_WD40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15598">
        <property type="entry name" value="ENHANCER OF MRNA-DECAPPING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15598:SF5">
        <property type="entry name" value="ENHANCER OF MRNA-DECAPPING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21289">
        <property type="entry name" value="EDC4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16529">
        <property type="entry name" value="Ge1_WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 7" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Enhancer of mRNA-decapping protein 4 WD40 repeat region" evidence="9">
        <location>
            <begin position="382"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="419"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="542"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="domain" description="Enhancer of mRNA-decapping protein 4 C-terminal" evidence="10">
        <location>
            <begin position="1249"/>
            <end position="1357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="139"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="250"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="784"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="9"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="43"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="92"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="194"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="204"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="254"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="290"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="804"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="847"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="909"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="933"/>
            <end position="951"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF21289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0023494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1387" mass="149547" checksum="416104106B0B18BA" modified="2023-09-13" version="1">MGPPPPPMGQMMPGFGFNQQGIDPHQMYLHQMMQHGQRAPPMAQFPPGPSPQSRPPPQGNALASLLQSLNQPAAVSPTNTSVPTFGAPPQPQQHQPVSQPHTPPSQADLQASTESLKLALFGPPKQEVTTAQQKTEDLKLALFGGSRPDLAQPQPSPKKEEVNLLAMLQRSSNASSPVPQPHTDNNLEGTVEIKGVETRKDSATRSPASKDNTPQSSSKAKFTYVNPFHSFTSPTNVVASASAAATTVPTTTPGINASPSHSTAKAVTGSQDSTLAGSSSKRSSFSAPGPRRETASHPEPDTSSHPRDDQKRYQLDQLLPPHSAWNHRVQKLAKGSSSIPDGVYLSHPGSGITTYDTGLDNSDAIFSEDLETIPITLIATDVEYNHGKMVAVSKGYISYAAKGGKIRVIQQSHGHRTLLRGHTDQIIDMGFSSASSQDPSGMQLLASIGRDSKLVIWDLSGSNADSTDIAHSKYLELLGEPQSDQPRYSRIAWSPVNPSQLALVNNDEHSVVIVNIHSLVQSQAGNSPVVSEAQIWSHSIVIRAHDQAINDISFSRDGSVLLTASEDGSVKFWALNTAAQEPALLNEFVPHGGLGVTNAMFVDQPDAATSRCIVTACRRGTELSLWHVAGSGPLDQLVFKEPPSSARRSSVGKAALRLQELRMFNFMGYDHETSSLVLANSSRLSLFGLKIKVTSTLDGAAVPNDLDQAAYIKAFVATEETAPCAATFDFMIEYPMPQPVVSFVVTPDSSLEYNGFSVYCIQAKAVQQYIIKGLEPHDKHKCQTFVSAPPSVKPTESKPKASPRANTPKSSSSPSIKVDDNVDSLATFKVEKSTTDPNPTTAAAQHETQDKEPEKSIKLHGPVINGAIAKLKEKKRNSATDGQPQAEGSEKKDSTKSSTSGRAGRKASQDLSTNVSHQDSATAKKGQEVKLSAETTKASVRNGRQSSNRHQDVNDASLNLDQVPPVAPPGHITISVGELQSMLQAMEDKIASRFEKKLSAELEQQYRKMDQDQISRQEAVLKMVSQTLTKNTEQLLVQTVNKEIQNSVVPSLNKIIGNAVDRQLSRTINDATLKALPSAVESAVKENIERVLGSPAFITNLTTQVASTIQPSIETCFKDNFTNLLIPSYQKATQAMFQQMHTAFSSGIEDLMSSSGKGNESIEQIASYVGKINSTVENLTLTLNQFVQGGSEQVSISNSSHFGQQRKSAAAIELQKALQGEGYTGNASFGARRSSQLTSPVESKQTAAINEFVAYGDFEGAFTQALSTNEPSAVFQICSKVSPRAVFQQTSTNPSGTLSQPVLLALAHHLANKQLSQNLGIKLTWLQEILMRLNPKDPQIGDHMTRILPTVKQRLEETSGELMSSGEVSPHLHMLQMLLRYVNNMIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T4A7</accession>
    <name>A0A9P6T4A7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_006088</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000030">
        <property type="protein sequence ID" value="KAG0024079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T4A7"/>
    <dbReference type="OrthoDB" id="2354716at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0024079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="160" mass="18240" checksum="4FAE150C2A147872" modified="2023-09-13" version="1">MGSDWYSFVSTTIIGIPIPKEALKSKFEKKGFSIMTIQNVVDEGEIEIEYHGAFLCPEDTTIENETSLEVIGPYIIEYAVAQSKKLDHLDKYLPNDLRDALIKEYESFVGKKPKFDPGFWVVSSTSSYNLDLHSEWAMGSNERVAAKSKKYDGFFYEVQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MD38</accession>
    <name>A0A9P6MD38_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_008345</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004499">
        <property type="protein sequence ID" value="KAF9992918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MD38"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9992918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="268" mass="30137" checksum="82930F35D2A98D98" modified="2023-09-13" version="1" fragment="single">MKQYKLKPWKSESDDLEDISVAPVNDSIENPKVPRRGPRLPAVDRMTKAEMVKALAWEHPFATLDIGTVAANVRSALKIKDVIKDPEVAVKDNEVAEGTIKCLRDIVKEANRTKRRCQQLLGTYIEQFKTKGLTPRDKNFFEHLCPSIPPKNTEGSDSSSILPVIDLNPDRDNDVGSGQTDKQVQFITCFMGYLYSNNFPRQVGVGGIVNDFIARLKEMGLHQPLRGQGEINVKPEFSPTALLRSVSVQLAQELMKMYWYGSYAILDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MEU5</accession>
    <name>A0A9P6MEU5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_007439</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003804">
        <property type="protein sequence ID" value="KAF9995736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MEU5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9995736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="442" mass="49507" checksum="1572481DD027D00B" modified="2023-09-13" version="1" fragment="single">MAHKMADCIRSHFRKLPSTVVNKMKKCGFPEDSIPNIADEDEDESAGFEILNEHEEDDDDDNNDSESFQSGHIKLWWQELCRLPKSCRPVFCPSAGYSDTFLEFSEEAMIGLLWGGGKKGLNHPTRSFMESWMTRSDAEAMAKENPGGLFHALLIGVQIEVAEKTGVRQTSYGRQTTTMRALSAPPTGDHPGHDELQLPQLREHVRNLFRYRADLAKFNESPLSTGGIPPERPVIHRPEGAKRYAASNLIATDGLRIHLHAFDLKHPATSSHDRVALKDITSVYEGKPVSNDELQGAVVVGIDPGEVISAAFCALDAEVPNGLRNLLVRRKTLYEPTLKYRSLLQKMKQHRDSKIVENNQRIPICIITPSISELESGLNVSNISDPVVEAKENLRRIWYIFSELRSFYGSHTVKKLNFSRDNAMRTEFDLSVTAGLSLVDPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MFE5</accession>
    <name>A0A9P6MFE5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_007251</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003682">
        <property type="protein sequence ID" value="KAF9996412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MFE5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="171"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="22"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="177"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9996412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="196" mass="22667" checksum="7048775BC219D66A" modified="2023-09-13" version="1" fragment="single">GRQDQNTEFFQHDLEAGLAPFLRLQLDRKRAAEQEAERVARERANAEEFEYQEGQLEELIKQMVTTLSSCLALRQEGGKWSMDIMKSRENNNDTSNNDDINVSQPVTALAWFQRRLALGEEIGMVEFSKEFGYIHEEDAHAAFMYPLSSTEIPRSTRTKFTREYETWRRNEGAEYWTSPSSPTKSSKPSGSTEERQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MGK5</accession>
    <name>A0A9P6MGK5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006539</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003231">
        <property type="protein sequence ID" value="KAF9999602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MGK5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="112"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9999602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="377" mass="42307" checksum="83D39A8DB50829BC" modified="2023-09-13" version="1">MIVSQGSTDNPMYRHCSDVEEAYKYDYSVTFDRERREDSTTVYSGVNHAKNMDPFAYMERVRNAPVKTLNDIELAGWLSVGGFWGREIASALPVKMMFLAAPAEFATNISHLLVLRKKLVQLNKAADDLNDDILRAQSRRNILEFMDIRVRRRIMTGCNDPVPYGDLKGIHALAVGGNWSGLTSEWGVARWPDLPRQPYPLLDGIAAFTNAIASFHRDAYDGSTNSLDGIYGFGSKEVCHDLRNIATTVRSTKGSLRIAYLHLFCLNYGKRYALWTDLAVMVRQPIHVDKSSFDQYLQDIFGPSADQDNHEKMYQTFSDIIDVVTRAFSVLSAKNALLSPEPWKSQIRAVNSLFVTSLCNHLEDGCSAKAVTVAAQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MH32</accession>
    <name>A0A9P6MH32_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">SAM-dependent MTase RsmB/NOP-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_006502</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003206">
        <property type="protein sequence ID" value="KAF9999813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MH32"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1170">
        <property type="entry name" value="Sun protein, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049560">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001678">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049561">
        <property type="entry name" value="NSUN5_7_fdxn-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048889">
        <property type="entry name" value="NSUN5_RCM1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023267">
        <property type="entry name" value="RCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22807:SF4">
        <property type="entry name" value="28S RRNA (CYTOSINE-C(5))-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22807">
        <property type="entry name" value="NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01189">
        <property type="entry name" value="Methyltr_RsmB-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21148">
        <property type="entry name" value="NSUN5_fdxn-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21153">
        <property type="entry name" value="NSUN5_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02008">
        <property type="entry name" value="RCMTFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51686">
        <property type="entry name" value="SAM_MT_RSMB_NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAM-dependent MTase RsmB/NOP-type" evidence="7">
        <location>
            <begin position="124"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="472"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="507"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="528"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="380"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="230"/>
            <end position="236"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="301"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9999813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="537" mass="58733" checksum="7E4DAA138A4AB4B3" modified="2023-09-13" version="1">MNFYKQAAQILDRLGKKEGSIKGLTLGNAEVTDKKRMYAVICETLKHNTTLSLVLQESKLLTLEKKLTRSLALLLLHDLLLQSRGIQASDAWPMKQAVMRHKARLKAEFVKARIKVGAKKDGLVEGEDELLLPRYVRVNLLMMTPQQVIDAFIADGWTFLSAPPSPLAPPAPNTFHRDEHLDFMLVFPPKSDLHLHPLYASGVLILQDKASCFPAAILAPPKNAYVIDGCAAPGNKTSQLAMGMGNGGKIIACDLDLRRLNILKRLTTKAGCTNITALNTSFLTLDTSTPDHSKVSHILLDPSCSGSGIINRLDYLVDAYAEEQEQATILETTTTGGAAERAAAEEKKKERLKSLGEFQIECVTKAMTFPNVRKISYSTCSIYAEENEHVVTTLLKNHWPQWKLSPRSKVLPTWHRRGYPADVGDIPGLVSTDEDRAKIADCLVRAVPGGPDGDLMNGFFVACFERVGKNDNPGLSPLWKGPSIGAKRTHEGMEADGATPAATTTPAKKKKNKKKKKKPSALVGDGSENEHGASDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MH90</accession>
    <name>A0A9P6MH90_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Oligopeptide transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_006556</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003242">
        <property type="protein sequence ID" value="KAF9999507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MH90"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035673">
        <property type="term" value="F:oligopeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004648">
        <property type="entry name" value="Oligpept_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22601">
        <property type="entry name" value="ISP4 LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="153"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9999507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="192" mass="21504" checksum="98046DB009C3AB82" modified="2023-09-13" version="1" fragment="single">MSDQKNEYANDKDFVDEKYDVERNSIVLDEEENSPIPEVAAIVSNKDDPSLPSLTFRFWIMATVFSILLGFCNQFFWFRENPITIGVSVVQLLAYPIGKFMAKVLPSGFLNPGPFNIKEHVLIALAANCAGGTAYAIDIIVIQKVFYKADFGFLANFLLVLTTQMLGFGMAGVLRRYLVYPSAMIWPANLVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MIM4</accession>
    <name>A0A9P6MIM4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glutamate decarboxylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_005767</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the group II decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002835">
        <property type="protein sequence ID" value="KAG0003600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MIM4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45677:SF8">
        <property type="entry name" value="CYSTEINE SULFINIC ACID DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45677">
        <property type="entry name" value="GLUTAMATE DECARBOXYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="6">
        <location>
            <position position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602129-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0003600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="629" mass="68908" checksum="C96DAB7977E78262" modified="2023-09-13" version="1">MDKSRQVDGRLVDYKEPEELEQIMDFSLPDQGVGPEGIFPTINQTLQYSVNTFSPRFMDKLYAGTTPIGVMSELLLAGLNGNSHVYHVSPVFTLMEIHVTRALANLCGFTGPLAGGLSCPGGSASNQLAMVTARNALFPEIKKHGYFPRPSVQEREELEKQGYYIRPSASTYGKLIVFTSSAGHYSLEKSAVIMGLGTENVVGVPYDSYGAMIPSELERLIQEHIALGHTPFFINVTAGTTVLGAFDAIRPCAEIAKKYNCWLHVDGSWGGCAIFVPELAKTLLDGTELAQSITINPHKMLQTSLQCSLLLVQDTSVFPRANSLKANYLFHGQSHDLADGTLGCGRRSDAIKLFLGWKYYGKLGYQARIEKSLSNVKRFVELLAQDDYRGQRIQMLRLGNDRDDCEDGRATKGGKDMYQPSHLQVCFWYRPRGSRLIDWRGTEQACKDSVELSSSTASSRIASAAGTPPLKATNQPYLSQAISSFVSEDDTLLAASATPSPNSSSVSLVSSVSISSNASSSSTATSTLAAAPSKIDHGLILRDPEEQQEAKAWMERVTKAVHARIRVRGEFMIDYAPFGTYSPIFFRVVLNPPTIREIDLVKLVEEILECGEAVADKIPIPEFCREKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MIV7</accession>
    <name>A0A9P6MIV7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005979</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002948">
        <property type="protein sequence ID" value="KAG0002417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MIV7"/>
    <dbReference type="OrthoDB" id="272077at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0002417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="301" mass="33911" checksum="578BDFB396F18C7E" modified="2023-09-13" version="1" fragment="single">MEWLAKSANQGDPYGQINLGEIYRSGFGVRKDLAKAMELYILAANQGLGMALCAIGTMYHDGEGVPKDESKAMEWYLKAAYQGDGHGMNLVGLMFLEMTGFQPDYFKAMAWFHKAANKGYAEAYFNLGRMYENGKGVPRDYYKAIVWFQKTADKGHARSQFAIGEMYCHGRGVLKDYTEAMEWLLKSANNEDAKAQIIIGDMYRNGEGVPKDFSKAMEWYTKAAKQEDADAYTRIGTLYHDGTGVLRDRAKAETLYRKAVAKGNAEAQFCLDWMHNDDQGAQIDQSKAMMFRKVAEDKDPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MKH1</accession>
    <name>A0A9P6MKH1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_005318</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002629">
        <property type="protein sequence ID" value="KAG0006295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MKH1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000125">
        <property type="entry name" value="Putative zinc finger protein 143"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000072">
        <property type="entry name" value="zinc finger protein 143 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24394">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24394:SF23">
        <property type="entry name" value="ZINC FINGER PROTEIN 281-LIKE ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13912">
        <property type="entry name" value="zf-C2H2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="489"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="519"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="547"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="100"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="211"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="301"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="379"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="441"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="16"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="118"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="144"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="211"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="237"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="467"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0006295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="583" mass="61223" checksum="7E833133959BEE4A" modified="2023-09-13" version="1">MDPIPSDESPSVQDNSSSPQQGTSPTPTDIEAVAAVTSQAFSVNFSQSTADEIRALTDALTTPLQEIVNKAQTDSPASSETAALGAAVAATVAAATAGLTEHVGEETIPGQESEDQQRQQQQQQQQQQQQQQERTDEETKDSSTEQVTETAELAKSSSSELDVDSVYNQVLSLTSQSQKPVGKRSAEEAFEQNQAARALQLIALSLSNPSAATTALAAPSSPSATPASGESTTLPESTSDTTHTSHVSEGALKGHDTGASVSDTLMSISRAINFPAQSTSASNIEADTEAFTRAVISATQNEANKSNNNAIPSSDNQGSSSLDHAALQNLSLHQHNYTSESGASSSDQAAAVAATSAPASVPSSSSQGFTFEIDKATGKTQIKWTPNPRDETNNELQDADTKAIQQALATIMANSGITGLSDLAGPNAALLAPPLGPFPVQGSEFGTAQDPVKTEPNSIPRKRRRANPSTSKSANQNTAASIPEGAPSFPCEFPGCDKVFARLYNLKSHSRTHTDERPFVCSSCQLAFARNHDLKRHVKIHGGDKSFLCSGCGKSFSRLDALRRHRANSKNRPGCEVTENSST</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MKJ1</accession>
    <name>A0A9P6MKJ1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_005222</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002590">
        <property type="protein sequence ID" value="KAG0006569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MKJ1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0006569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="66" mass="7900" checksum="EBAC22B1E8D16501" modified="2023-09-13" version="1">MTRMDTHMPRELDSVPRTWADALMIECLRKMMEVDQTMIAHEREQMIVKREITLTEPSLLVQRTKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MKL7</accession>
    <name>A0A9P6MKL7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Carrier domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_005508</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the NRP synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002711">
        <property type="protein sequence ID" value="KAG0005114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MKL7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043041">
        <property type="term" value="P:amino acid activation for nonribosomal peptide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05930">
        <property type="entry name" value="A_NRPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19544">
        <property type="entry name" value="E-C_NRPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.30:FF:000010">
        <property type="entry name" value="Enterobactin synthetase component F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12780:FF:000012">
        <property type="entry name" value="Non-ribosomal peptide synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.980:FF:000001">
        <property type="entry name" value="Non-ribosomal peptide synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.38.10:FF:000001">
        <property type="entry name" value="Non-ribosomal peptide synthetase PvdI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1200.10:FF:000005">
        <property type="entry name" value="Nonribosomal peptide synthetase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.980">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.38.10">
        <property type="entry name" value="Luciferase, Domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020459">
        <property type="entry name" value="AMP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF1">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00154">
        <property type="entry name" value="AMPBINDING"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="600"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0005114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1229" mass="135370" checksum="A33C022D7E2323B2" modified="2023-09-13" version="1" fragment="single">MTFKPVEIDYDVVKFDIDLSLSESNGEVVGGLIYSTALFDRSTIDRHVGYLQTMLQAMVNSETESISAVDILSSSERELLLQTWNSTNMPYPDRLCIHQLFENQAEQSPEAIAIVHEDQQMSYRELNARANGLAHHLIGLGVKPDSLVVICIDRSLTMIIGLLAVLKAGGAYVPLDPSFASERLHGILNDVAPSILVADDTGIAALGSSISESTVVVNPNVLSKISTTNPHVPKLTPEHLAYVIYTSGSTGKPKGVMLEHQGVANLAALRPKVFGVDSSSRVLQFFSLSFDASVHEIWSALCHGGTLHILPNNVRQDLALLWSYLEQQSITHAALTPTLLQHHEDLLPLHTPLTMVVGGEALSSSLINVMRTLIPNGSIINAYGPTETTVDAIAWKCPGDFNGDIAPIGRPHPNKRIYVLDSHRKLVPMGAVGELYIAGAGVARGYLSRSHLTDKVFFSDPFTPNNKSRMYKTGDLVRYLPDGNLMFLGRDDHQVKIRGYRVELGEIEARLLDHTLVREAAVLALGEGSSKRLVAYVAADPTKELAHTLRSHISAKLPEYMVPAAFIRMDALPFTLNGKLDRRALPEPGSDAFVSQRYEAPQGNIETALADIWADLLKIERVGRHDNFFMLGGHSLLAVQMVERLRRVDLNLSIRALFDAPTLSALSQSLNKHHVETMAPANRITPDIATITPDLLPLIDLTQDDIDTIVKQVNGGITNIQDIYALSPLQDGILFHHIMATKGDPYLLINCMSFDKRDTLDNYLEAFQKVVDRHDILRTAIVWEHLSSPAQVVLRQATLSITEMVLNPADGPVSKQLMKLFDPREHRIELSQAPLTRFVIAQDVDDRWVVVQLMHHLIGDHSTLEQMMIEIKAFLDGRGEALPSPQPFRNLIAQARSGSGIESHEKFFTKMLAEIDTPALPYGVSDVHGDGIDVTEAHYTLPQVLNNRLRDHAKRMGVSLASLCHLAWAQVISRTSGQEQVVFGTVLFGRMQGGSGSDRAMGLFINTLPLRVDVDNRSVLDSVLRTHTDLAALLEHEHASLALAQRCSSIPAGTSLFSAMLNYRHNSTPSSDESQNFTGINTIEAIERTNYPFVMSVEDGGVSLGLTAQIVQPFDPVRICGYMQQALQSLVDALDHSPEIPVRKLEILTGAERELLLQTWNATNVTYPDNLCIHHIFENRVAQSPNAIALSYESESLTYNELNVRSNILAHHLISLGVKPDSLVAICVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMS6</accession>
    <name>A0A9P6MMS6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Suppressor of loss of ypt1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">SLY41_1</name>
        <name evidence="8" type="ORF">BGZ80_004317</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002210">
        <property type="protein sequence ID" value="KAG0007728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMS6"/>
    <dbReference type="OrthoDB" id="1588579at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004853">
        <property type="entry name" value="Sugar_P_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03151">
        <property type="entry name" value="TPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="383"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="416"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="444"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="473"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="498"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="559"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="590"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="617"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="644"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="domain" description="Sugar phosphate transporter" evidence="7">
        <location>
            <begin position="353"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="93"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="124"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0007728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="720" mass="77735" checksum="151A01DB00EAF95E" modified="2023-09-13" version="1">MATAATATSVPPLRQPMSYHGSKAQPQQQHHHNNNQEHSQTTADALFASPATNTINGGDIPFFDSINDNNNNNNNNMPSNLNNPLMVHVHQLPTPRTSFSSGSSSPPENLSPGAHPSLAFNNHLTPTSFTPSSVSSASSPSLTLPSTLASTPSQSHVNAYGPSAIPATKSPLSVSHMYQAQAQPTLRSTSPSLNSTLGPALYGSSAVPSSNNNSFTTPAVNAPFNSGSGIYNIGGVSGNTLGGRLPVQAQQYNEQQFQMQQEQLYYDEQELQKKNSRSALHSVTAFLPPALNQGLNKVVQSAQAAVSSNSKLSLPSSRPLMDGTFPSSSTSTGLRVDPSSTHGMLLKLYKASKLPILCLLWYLSSAVTNNIGKQIMNQFRYPVTLTFVQFVFVSLFCFILGSGFRMTTIRKPTVAIIHMTAPLVGFQVVGHVFSSIAISRVPLSFVHTIKALSPLFTVVFYRIILGTTYSREVYISLVPLTAGVMLACRLSLEFNNLVGLICALASTLVFVTQNVFTKRILFSTKTTKLGGLGNKESTKEDDSVEEGSTNAQKLDKINILFYSSTMAAICMIPIWLYAEGMGLMFPDESGVYHHTAGHSSGFWAISWLLFLNGVSHFFQNVLAFSVLALTSPVTYSIASLVKRIVVIVASIIYFHQTLGTTQWTGVALTFWGLWLYNSAKNAAKVRPNGGILANTKVGRRMSRNFGRGLLDTDRKGGFLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMZ8</accession>
    <name>A0A9P6MMZ8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_003624</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001973">
        <property type="protein sequence ID" value="KAG0008279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMZ8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0008279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="137" mass="15579" checksum="700E4093C5441CA1" modified="2023-09-13" version="1" fragment="single">MGIQLQDLARNFAYTRKMCWHSNKALRQRRVNIDSQVLSPQISSNGLAKILSLMPNLRSLELHMDAYSVISAFENLTKLEKLELNMLSRSTAGFPFHEFGALFSRISCLKLVMPPETRRVSLDDLPATNSWAVNILE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MN72</accession>
    <name>A0A9P6MN72_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Serine/threonine-protein kinase KIN2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">KIN1</name>
        <name evidence="10" type="ORF">BGZ80_004589</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. NIM1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002322">
        <property type="protein sequence ID" value="KAG0007509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MN72"/>
    <dbReference type="OrthoDB" id="193931at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14077">
        <property type="entry name" value="STKc_Kin1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000792">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF82">
        <property type="entry name" value="KP78A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="326"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="261"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="699"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="804"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="903"/>
            <end position="987"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="52"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="68"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="87"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="113"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="140"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="177"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="216"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="290"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="703"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="723"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="766"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="819"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="903"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="936"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="355"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0007509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="987" mass="107685" checksum="E97C4B8A259EDF83" modified="2023-09-13" version="1">MAIMPTTTPNTLQTPSSLESKTIKTSPTRANSQPCYDKDLPPTPTSSSHLGSSDVAPSSPASHPPTSEVITSTALEPTPDNSTHQLASSSSSASSTSASPATPMIPAPTASSNPPQTITLTPGNHERDDLYVSFKTVAPNTTTNNDTSNNSNMDKAPSKRVTLLEPPPPYSGDNLVQSQKHQQQHPQSQQPVASSNTHAYRASGPESALILPQDNTPSSSRTTTTRTSTTPEPSNGPPLQSLHQHLQERNGIVDDHASLSLSHRHSESSSNNNDQFTNNITNGDDHRQDTASSNDHPDGQSSQGTSTDPNAEDPSRIKPRRVLGNYHMSKTLGAGSMGKVKLGVHSRTRDKVAIKIIPRVQPNANMTPAQQEKEDNRETRTIREASIMMVLHHPYIVSLYEVMVLPHHYYMVLEHVDGGQMLDYIISHGKLKEKHARKFARQIASALDYCHRNSIVHRDLKIENILISKSGNIKIIDFGLSNLYSPRSHLSTFCGSLYFAAPELLNAKVYTGPEVDVWSFGIVLYVLVCGKVPFDDQSMPALHAKIKRGFVEYPAWLSNDCRHLLSRMLVTVPSQRATMAEVLAHPWMNKSYDLPQPSYCPQRSPLTEPLDMNVIRGMTGFEFGTEQEIEQRLLSIIRSESYQTAAKNWHALNMSVSGTLSHKKKMQSFAAREAELQIPLTTPLTSIYHLVREKQAREAMQRMSAQGLSGSMSSDIQNGGADQFSGGSQHQHSQSVRLQPQQQQQLSSMHRQSMSQVSSDPRSDVSSNDNHSGHGNSSTIGPSSAMSSARSTLSGFASFGRKSLRPRAKSVAGDLLRSNTTGNANANSGNNNNNNNNGHYGNGSGHGFANGPSREGSIKSSKGSERGLGHSAAAHAARSLFGSVRESSGGVLRRLSLVFNNHGDRDKEKEKDRVDSNGNAREPTHARHHSAKLERVSPSPRSFSFGRPQSMRARPISMAESLDRPLPPMPKEAYEQSAYEPSFTSIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNA6</accession>
    <name>A0A9P6MNA6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Prolyl endopeptidase</fullName>
            <ecNumber evidence="3">3.4.21.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_003350</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Serine peptidase whose precise substrate specificity remains unclear. Does not cleave peptides after a arginine or lysine residue. Regulates trans-Golgi network morphology and sorting by regulating the membrane binding of the AP-1 complex. May play a role in the regulation of synaptic vesicle exocytosis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the peptidase S9A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="3"/>
    <dbReference type="EMBL" id="JAAAID010001881">
        <property type="protein sequence ID" value="KAG0008518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNA6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002470">
        <property type="entry name" value="Peptidase_S9A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051543">
        <property type="entry name" value="Serine_Peptidase_S9A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11757:SF19">
        <property type="entry name" value="PROLYL ENDOPEPTIDASE-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11757">
        <property type="entry name" value="PROTEASE FAMILY S9A OLIGOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00862">
        <property type="entry name" value="PROLIGOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase S9 prolyl oligopeptidase catalytic" evidence="4">
        <location>
            <begin position="96"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S9 prolyl oligopeptidase catalytic" evidence="4">
        <location>
            <begin position="287"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00045448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU368024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0008518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="388" mass="43665" checksum="2FF1BDDA7A440FAC" modified="2023-09-13" version="1" fragment="single">DYETDSFQFTLNSPYAHEASYEYDMASRVMTALRVHPIHRLDRSKYTCTRINVTAKDGEAKIPVTLLHRKNMQLNGRNPTLMRAYGAYGVPTDIDFRVEHFPLLERGWIIALAHVRGGSELGTLWYHQGKLENKRNTFTDFIDVAEHLVEAGYTNPRRLTATGVSAGGLLMGAVCNMRPDLFRAMVLNVPFLDPMTAMLNPETPLTKVEYLEWGNPAESEKMYDYMASYAPYDTIPEYDNDTSRKDRTVRQIANGSSDGSDAEDSSSTTVITTAGTATYLPPPITARRPALMISCGERDQRVDYTQSAKFVARLRSRLEPWYGAEGKEACVLMVDENRGHFGNGSQDDRVKNWAREVVFLLGNVQQMDVGGSNMSMGHNNNETAYRQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MP57</accession>
    <name>A0A9P6MP57_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Ras- protein Rab-2-B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">RAB2B</name>
        <name evidence="8" type="ORF">BGZ80_002850</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Endomembrane system</location>
            <topology evidence="7">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001725">
        <property type="protein sequence ID" value="KAG0008985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MP57"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01866">
        <property type="entry name" value="Rab2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000263">
        <property type="entry name" value="Ras-related protein RABB1c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050209">
        <property type="entry name" value="Rab_GTPases_membrane_traffic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47979">
        <property type="entry name" value="DRAB11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0636">Prenylation</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0008985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="214" mass="23464" checksum="A128568613235967" modified="2023-09-13" version="1">MSSSFNYDYIIKYIIIGDTGVGKSCLLLQFTDKRFQPAHDLTIGVEFGARFVSVAGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFKHLTTWLEDARQHANANTTIMLIGNKSDLESKRAVSYEEGEAFAKANGLFFMETSAKTSANVEEAFVETATNIYEKIQSGIFDIHNEAHGIKIGPMHTGGSSLPIGPANGSGGCCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQ15</accession>
    <name>A0A9P6MQ15_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Coiled-coil-helix-coiled-coil-helix domain-containing protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">CHCHD2</name>
        <name evidence="4" type="ORF">BGZ80_003008</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001771">
        <property type="protein sequence ID" value="KAG0008835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQ15"/>
    <dbReference type="OrthoDB" id="1106148at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010625">
        <property type="entry name" value="CHCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055304">
        <property type="entry name" value="CHCHD2/10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009069">
        <property type="entry name" value="Cys_alpha_HP_mot_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13523:SF2">
        <property type="entry name" value="COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 2, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13523">
        <property type="entry name" value="COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 2/NUR77"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06747">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47072">
        <property type="entry name" value="Cysteine alpha-hairpin motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHCH" evidence="3">
        <location>
            <begin position="128"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="9"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0008835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="168" mass="17619" checksum="0E390B1765091EA6" modified="2023-09-13" version="1">MARQRSRAAPSQQTRKASTMPTRQAPPPPPAHAAPQQHHNQMAPGQQQSSAMGHPAPRQPGLFGQMASTAAGVAVGSAVGHTIGHGISSIFGGGSSAQAEASEAQQPQQYQQPNYYGNAAMPTSSTSCDANAKAFTQCLETNGNDVSRCQFYLEQLKACQAFVAQQQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQP7</accession>
    <name>A0A9P6MQP7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DUF1014-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_001747</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CCDC124 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001402">
        <property type="protein sequence ID" value="KAG0010148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQP7"/>
    <dbReference type="OrthoDB" id="76412at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010422">
        <property type="entry name" value="Ccdc124/Oxs1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054414">
        <property type="entry name" value="Ccdc124/Oxs1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054413">
        <property type="entry name" value="LSO1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21680">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21680:SF0">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06244">
        <property type="entry name" value="Ccdc124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22048">
        <property type="entry name" value="LSO1_2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LSO1/LSO2" evidence="5">
        <location>
            <begin position="6"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="Coiled-coil" evidence="4">
        <location>
            <begin position="108"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="124"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="205"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="45"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="207"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF22048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0010148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="228" mass="25397" checksum="CE080781A2675C92" modified="2023-09-13" version="1">MPPKNAKAAAANERKAAAANEKNAKKAAEKEAAEAADWAKGSKANKKEAEEQKRQEQLAKKREAQRALEEEEKGLKSKPSKPIKGEEKKAVKKAQKVEAFSSEVKPVEEFSASNIDDALDLLSLTGASTGGSGQGPTTTGKGKDVDRHPERRFKAAFAAYLEREMPNLKKEHPGLRQNQMQDMLFKQFQKSPENPFNQANIISYDANKQEEREHIESRKQEIANRLRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-06-18" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQS7</accession>
    <name>A0A9P6MQS7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BGZ80_001616</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001371">
        <property type="protein sequence ID" value="KAG0010292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18596">
        <property type="entry name" value="ABC_6TM_VMR1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18604">
        <property type="entry name" value="ABC_6TM_VMR1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000997">
        <property type="entry name" value="Multidrug resistance-associated protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF356">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER ABC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="49"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="79"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="113"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="318"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="343"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="424"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="854"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="943"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1020"/>
            <end position="1037"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1043"/>
            <end position="1063"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1132"/>
            <end position="1152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1158"/>
            <end position="1177"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="194"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="565"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="866"/>
            <end position="1182"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="1222"/>
            <end position="1501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="270"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="799"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1340"/>
            <end position="1386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="799"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="814"/>
            <end position="836"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0010292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1531" mass="170988" checksum="B7AEF93C2DFDC14C" modified="2023-09-13" version="1">MSINLARLGLTFLQLGLAIFSIVLLRSPNDDDDDNNGQQSTINEIAQALAWSYALVLTFVHVIRPTVSHQFLIRPQLDLFYVLQFILLSTRLYFTDIFILPLLGWPLWLKLDVFAWLIVGCLIWTSLVTRPFEAPAPARKLEAGEIPRVESPEYPSSIFDQLTFSWVNSLVYLGFKRPLQDFLWAMPWCFLVNASPYCMNKIIQYIECPTCGPPTMSEYAWVFGLLIASILESLVQQAALHKGRRIFVHTASICNSEVFAKTLRRKDIASTDKKDDKDDKDDKKDSKDGKDGKKKEGGLNISNLVAVDIRKLEFPFSYIFYIYGFPIQFIIAGFQLYNLLGNASLVGIGFMIISYPIPAKLYAMIMKLFKDIMNTKDERMDALNEMLSAMRIVKFFGWEGKFEEKITAAREKELKRTRESYTKIILTDIVWMIMPLANIVVILTAYTKLFGHEITASKMFTTLALFNIMRSALNTLPWCIKSTMQAAVSLDRIDQFLTEDEILKDTTITKIDGKAPASSTHPIIGFVNASFIWPNKENDEASAKTEKKLNWVQKIKAKFSKTPTPVVEPVAEVAVQERFKLKNISIDFPVGQLSLVVGATGSGKSALLLALLGELERLEGNVYMPRLDYGLDYDSDRGSGIAYVSQTAWLQNSTIRDNILFGKEFDQDRYDAVVEGCALATDFDILESGDKTEIGEQGITLSGGQKQRLSLARAMYSDAKVLLLDDCLSAVDTHTGKHLFQTLTGPLAEGRTIIMATHQVQLTLNAASLIVVLSKGEILGSGSAEEVVRNNWVENVTLTSPASGDNSEVSTLNGEDKDKDKKDKKDKKEKTSVKLTEDEKKTEGAVAWKVYKTYLVASGGAIFWSGLVLLFFVREFVDISQNAWLAIWANRMAESTGSFIMKTIESVAPSVALSVYTAFRPVSEDSSVFAFGDDVPEKASVDYYLGIYVLLSTAGMLLGSITQYYVIHGGLAASRTLHQQLLRKITRAKVRFFDTTPIGRIVNRFSSDISTIDEDVSNNLQGLFSSFVTIVGIIFIISVNMPLFLVAGVFIVAIYAVIGALYLPISRDLKRLNSNSKSPILNHFNETLNGLATIRAYGFEKRFLSRNLVNLDNNNRTFFLLWSTNRWLHWRVDLAGASVAFITGILVLQNWGKIAPGWAALSMTYSLMFTGTIVWVIRIYAMNEMNLNSVERVVEYMDLEEEPAAIIEGSRPPASWPHAGEIVVDHLSMRYAPDTPDVIKDISFTIKAGEKVGVVGRTGSGKSTFAISLFRFMDPAKGTITIDGIDICKIGLQDLRSNLTIIPQDPILFKGTLRSNLDPFGEREDRELWEALRRSHLIPSSNEASKRNSAEITTDATTKDIEASSSNKSPAGSVKETKAKEEPEIVDSSKITLDTPVKANGSNFSQGQRQLIALARALVRQSKIIVMDEATASVDFETDLKIQTTIREEMADATIITIAHRIRTIADFDRVLVMNAGTVAEYDRPYVLMQQEDSLFRSMCERSSEFDALLAIAEEKERKDRESESARLLTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MR29</accession>
    <name>A0A9P6MR29_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Autophagy-related protein 101</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_001224</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATG101 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001277">
        <property type="protein sequence ID" value="KAG0010726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MR29"/>
    <dbReference type="OrthoDB" id="10259639at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990316">
        <property type="term" value="C:Atg1/ULK1 kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="C:phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="P:autophagosome assembly"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012445">
        <property type="entry name" value="ATG101"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13292">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13292:SF0">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07855">
        <property type="entry name" value="ATG101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0072">Autophagy</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0010726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="196" mass="22410" checksum="84F1E60703E1D0BF" modified="2023-09-13" version="1">MSHYQPVTFPVELTVEREFLNAALRAILHTILFHRVFANIKPRDMEILDLTIPVIDDPDIDKLVDERISAFVKAVDSNPQAKGQIGVMFYEKRTKRAWFSSTSSDVCWEQWVITINVVTNINEKDKQRSIKNMEKALSSLFLSILRTVNERKDHIPPITTSDGNPFPYQIVIPSPADTWGSMFKRMLDTSTSSPSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MR86</accession>
    <name>A0A9P6MR86_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GYF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_001308</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001297">
        <property type="protein sequence ID" value="KAG0010625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MR86"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00072">
        <property type="entry name" value="GYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051640">
        <property type="entry name" value="GRB10-interact_GYF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003169">
        <property type="entry name" value="GYF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035445">
        <property type="entry name" value="GYF-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14445:SF36">
        <property type="entry name" value="FI03272P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14445">
        <property type="entry name" value="GRB10 INTERACTING GYF PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02213">
        <property type="entry name" value="GYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00444">
        <property type="entry name" value="GYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55277">
        <property type="entry name" value="GYF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50829">
        <property type="entry name" value="GYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GYF" evidence="2">
        <location>
            <begin position="377"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="670"/>
            <end position="1018"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1036"/>
            <end position="1139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1212"/>
            <end position="1251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="286"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="311"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="326"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="352"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="680"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="702"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="712"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="807"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="833"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="854"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="864"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="880"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="919"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1001"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1059"/>
            <end position="1095"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1105"/>
            <end position="1135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1222"/>
            <end position="1240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1241"/>
            <end position="1251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0010625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1251" mass="135116" checksum="D61295C1A723C0E9" modified="2023-09-13" version="1">MRRFPAKSNQSNDQQVRAPSPPPASPHQDWNQLASSGAAMPAFSYSSIAASNVRSQNGASAQTSSFDTSLSDGGSGGNSGVSGSFAPDSLNPFKYSKELMLSLYKPTGLPIEFERHEYMTSEESLPPISFLQLSEQEVKLLAGSVNSEVARRTAQPGDSSQERTPGQRRESLSNTGEYSAGRYDRSDKNSTNTRTFESRNHGGGARPRNLNSEGRSHSFRRTEQIEREREREREPEDDGLWNSPVGNTVGSFDANGVFRVVGDGDELQPLSELEESTSKHVDDSESAANASAPSQSQELVSSDPGSIKADQSSPQQQQQLQQTLQDNSGESFMFSNSVLAGKGPLREDAEFAPFSQPPNSSAAPPSDPVFDSAPVELSKWLYRDPTGSIQGPFSSEEMHEWYKGGFFSPDLLVKREQDPTFEPLGSLIRKIGSEDQPFLLAGVLRQEQPPTPLRPSIPSLAQNRQAGSQMNLASGWVGMSAPSTPSAASFGVDRLLMQQQQQQQHSSGDLFSSTNSLGQQRAGFGLDPSVGMPGESRWGSNLFGGRAQNVEPSGGWGGDGFPRSSASSISAAHTPLGGPHFMDQQQRLHNQEIERQQFMQMLQRQSQMQAIMHQQQFMAAQQQFGNDPHALAALLAQQQAQQRQLQIRYQQLQYAGLHAQGVSTPGGTAIPWGGVGMGQPSSPWTTSIIPPTSDTYPDHSNNDGGQVPLSSQQQQQQQQQQQQHQHAPQNQMQHQQFQSTQQEQQQQQQQQQQYHQEENELPAEQDETPAHDLSSPQNGGVTADSLTERLESLEVSEEVESEHVQTEAVVEVEQVAESISVVEQVPVDEEEAKEPLEPTKEHETEPETSASLEIKQEYQHEQEQEQEDQQEQESAEENVSETASWTATESWTTTETTHRPIKASPAPWAKPANADEDSSERKGPTLREIQEMEAKRAKEVRAERQAQMAAAAATSGSGVLDFTKGMPGAPAWSSPASTTPKKKTLKEIQQEEEAAMKKARAAAATAQQSNVAASAPLSSQSTGLAAIVASGTGSIGRRYADTIGPKPATVSAAGPWGSALSSATGSRPTLSARSSAVFASNPSLNSTSSPASRDNSWIEVGSKHSSSATSSPAVSRASAPTSAPSSTKASSFSNSNEPRPASEEFLRWCRQALKDLQNVVLEDFIQMLLTFPLNPDPMTVEIISESIYANSKSLNGRQFADEFIKRRKADAYPNGAPASVNSASIPSGAGAAGSDSSFKVVSKKGKKKGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRM4</accession>
    <name>A0A9P6MRM4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_000869</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001191">
        <property type="protein sequence ID" value="KAG0011189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRM4"/>
    <dbReference type="OrthoDB" id="2384430at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0011189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="333" mass="36979" checksum="0BFF2A0E267249CE" modified="2023-09-13" version="1" fragment="single">MYTNAACIGNHRDYTIEKIKGAQEPATRGDPNACYIKGHASYDDHDYAKALVWYRKAANLGHADAQNRLGQMYEAGHGTSQDYSAALDWYIRSADQENADGQNSIGLLYYKGKGVPQDYEKAFEWFQKAAMKRHPDAWNNLGRLYDNGLGVEQDHHTAFKCYSEASAYDHAGAWVNIGIMYENGKIKSENGTSAPPDFPQAMLCYLRAADRGYAAAEALLGDMYNSGRGQPKNHSRAKDYYLKASKKENVHAQRALGLLHYNPGPLRDYSTAKTWIKKAADQGDAEALVTLGNMYLKGLGVTKDFLKATELFREAANRGDASGADSLQYSRQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRQ4</accession>
    <name>A0A9P6MRQ4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Exocyst complex component SEC5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_000779</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the exocyst complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the SEC5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001170">
        <property type="protein sequence ID" value="KAG0011316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRQ4"/>
    <dbReference type="OrthoDB" id="26242at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000145">
        <property type="term" value="C:exocyst"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006893">
        <property type="term" value="P:Golgi to plasma membrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029175">
        <property type="entry name" value="EXOC2/Sec5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039481">
        <property type="entry name" value="EXOC2/Sec5_N_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13043:SF1">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13043">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT SEC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15469">
        <property type="entry name" value="Sec5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Exocyst complex component EXOC2/Sec5 N-terminal" evidence="5">
        <location>
            <begin position="91"/>
            <end position="907"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU365069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF15469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0011316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="911" mass="103983" checksum="5E7C730CA0F71002" modified="2023-09-13" version="1">MSSIVRDIQEIELLRHYHLDKTNPDIWVDEEDLPSWVHDDDVNIDHGGRLTPRERKAQYVEDDSSTISEQTDLLGLVKGNILKSKNVRGDINPISSTQKSFNPQRYLYAVHANTPYDDLCIGVDRLQASIAQRSSALKVLVQNNFDRFVSAKNVIDSVYDDMKEKTLNEAQDWGTNRLNTILRESYGKAHEVINPVLERREKVDKLRSTVGLLEPYRLFFNLPNTLQESIKQGKYQQAARDYNKGKVLLAQAFPSNSGSAASDSASTHSHSSSPSLTETKRRVFDRVWSEVGRIVARLRADLESQLEEPWRGMEEHERNIKLLFELDTTTDPVWHCLSSQYRWIKKIMAESYDEQTILVDELRKSDEYLQSQNMTINGRTALFKQILGAVNSSEFENMFAKEPEVKVWLAITAGVKTLSELLLRLLPDFWKLATAYMEGNIQKVQNQKRRTGVNVVDQQRVLQCYGMVKDIVELYSSQMTHMLIDNLVAEKQARQPGEDQEQDQSDPPTESSVVTAFFLGKIVTEVSNCVNDVNGLSLRGGSFMVLVDMMQRIRWKFVEVICETWGEDAKVFYNHEDWTLQTENSQITLFVGLFYQFHEYCLRSAYKYASIWTATTEEPVSNDEASAVVPAQYIEKIRKTFLDASYSFLDGLVHLAFADAERSNRQQQNLDGAGSLDNLQIGKKSKLIDITELDSRILITISNLSELRSVTIPKLLKDFERICGITMADDGKRLIETVDQLDNILFDDYIKRKTVVASRVITDGILYSGIDWYSIPKPTGVHAFMYEALLSLVVVHAQISEIAPPLVFRALSALLINMAQDCLRCFQQIERFGMGGMLQATLEMEFMNHTLAQYQSPSSDEILQMIYEVIDRAYHPEGGENLQNEMAALKKLLTDARQSTQVQFMCFKKPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MS16</accession>
    <name>A0A9P6MS16_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein fam86a</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">FAM86A</name>
        <name evidence="4" type="ORF">BGZ80_000711</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class I-like SAM-binding methyltransferase superfamily. EEF2KMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001154">
        <property type="protein sequence ID" value="KAG0011408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MS16"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029426">
        <property type="entry name" value="FAM86_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF130">
        <property type="entry name" value="PROTEIN-LYSINE N-METHYLTRANSFERASE EEF2KMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14904">
        <property type="entry name" value="FAM86"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FAM86 N-terminal" evidence="3">
        <location>
            <begin position="12"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0011408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="295" mass="32918" checksum="CFA1BC7E31BFA7F8" modified="2023-09-13" version="1">MDEASQRLVLLIKRQVLQMRQIRQFQWSLTDLQTSETGGATSPSVTDPDIQQAIVDQIFYDPVVMKHPPSLTYQHSFLKKLISMIETEGTHEISGDLLEIFTELLVTAPKRPEDGGPPLEPCFKSYSLDPECSKVVTVMEEQTTISSGTTGLRTCFWLAEYLIAHPGKLHRRIACAILGAKKVVLTDGNMEVLAMAKRNIEYNDIPCPTTASLLDWENFTEEQIAALEAEVLIMSDLTYDPTNIVPLVTVLKAILVKGVSAYMSSAIRNPQTFADFFARISKYLPSSLMNLVCFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSA6</accession>
    <name>A0A9P6MSA6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_000984</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001218">
        <property type="protein sequence ID" value="KAG0011048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSA6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="92"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0011048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="200" mass="22304" checksum="48A4AD9283347B21" modified="2023-09-13" version="1" fragment="single">MATVFPEDKDLFALYRNHPKCYDPLVEVLRRKARITIPDWKVLHNDKYCFDIVLSVKEKLERQTEVSKLEPQDAVTKSHEIMMTLLGDIHSVDVCLVAESDKTCSNVGLWAHRAILSRYKGFENAIQTACKDLSSTSEDMAKLTIGDGDSSSSTTAQGDGILGPLLIPVEKFTLATLCVLLRYVYTGQINLSAETNKHAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSG3</accession>
    <name>A0A9P6MSG3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">DUF2421 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_000239</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001043">
        <property type="protein sequence ID" value="KAG0012049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018820">
        <property type="entry name" value="BRE4-related_DUF2421"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052430">
        <property type="entry name" value="IVT-Associated"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049453">
        <property type="entry name" value="Memb_transporter_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47804">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47804:SF1">
        <property type="entry name" value="DUF2421 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10334">
        <property type="entry name" value="BRE4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13515">
        <property type="entry name" value="FUSC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="338"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="390"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="418"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="978"/>
            <end position="999"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="1032"/>
            <end position="1050"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="1131"/>
            <end position="1149"/>
        </location>
    </feature>
    <feature type="domain" description="Integral membrane bound transporter" evidence="8">
        <location>
            <begin position="980"/>
            <end position="1144"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2421" evidence="7">
        <location>
            <begin position="1150"/>
            <end position="1351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="227"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="563"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="648"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="861"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1078"/>
            <end position="1097"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1426"/>
            <end position="1685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="68"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="283"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="648"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="869"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1084"/>
            <end position="1093"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1497"/>
            <end position="1511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1524"/>
            <end position="1534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1540"/>
            <end position="1549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1557"/>
            <end position="1575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1576"/>
            <end position="1586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1620"/>
            <end position="1634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1635"/>
            <end position="1653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1666"/>
            <end position="1675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1676"/>
            <end position="1685"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF10334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0012049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1685" mass="187217" checksum="51C72B8B5C864339" modified="2023-09-13" version="1">MAHVSDNFKDSNDSLSRNSTPQGPVQVDFAAGVVGANDVTTQPQETSTDAPVSTLKNMPAKKSPSLDEPSSPTQLESTAAPSSPLQIHSTQMPRNAASATGGGPNISFSPLPLGRAYSESPQGHRMDEFIPSPVRSLGQVLEYAETSQSMQQHDVISGEDHWVAHASAATGASAVHFQPRRWSHGHRARVGAGTGSSGWMGTSVPESRFSEFEVVYDDGIRKQRTFSISTETEDSKGTISECDESERNPLLGHQDIQGTYNGQHQHEYADQQQDTDPAIPSSLGKNNIHYNSINDTEGRNRRPSLRPSNSPFAYFHDRLLDAWNWIAQLRLSLPNRRILKASLAYLFACLVSFTPFFHPYIGVSGHLAATSAVFFNPAKSLGRMVDAVTAGICAISFGFLVSVGSMASAVWFNNRNMYIWGHVVSVVVFGGGSTFIIAFAKAHFNRPTVNVGKFGSLIEGYEAQDMGKSLTSFRLLLKLLTKTFLLESDTTPFGSESVQKLIETQVKSFSALAKSLEEAQLEFPGADIKKYEDCVKSLNTLAQYLNGLRSSCGLQYDMLKKEEQRKGDQNQRVSRPPTSAPEPRPGLGRSMTMGSRISSFSVVGSLVSDQDNSASADLIEFLNHVGKPMKSLALTCKITIEHLQNIFTSTNGDHSPVTGSDSRRASHPYLRQSGYGSAEVFSDSTYDVGNSHTRSVPSLGKMQTNLAQALEIFEAANLKALKRFYSQHQRQQSEVYRRPAGATNRMSEPSLQDIASRLSNSAAGTELGARAGIEDPQDALAEKAPVGEQIFLVYFFVFNLMEFSKELSHLVSCVETLVGGDEGLSLWIARNRLTWWRRIWFTITGFPRRLRKRTEENDVSENFDYPDSGIQSPDISQRHQNQSSTSRNNYEPQQGSNTYGTIASRRRRKQRLFPKPNIHNTTNTLQTPVPSTFSQQLFTRLWKFLHLFRSFQVKYAAKAAISAIVLLIPAFVDWTRPYFVQYRGEWALISTLIVMVPTVGGTNIVAIYRVMGTIFGCIMGVVVYLLFPAHPIMLPLCCFMFALPNFYLVLNSSHPRLGQVVLLAYNLVLLQTYNRRNGDGTVPPDDDDDDDDDYSGHTPSTILRNMGTFADWNPSDPSYVSAVMTIALHRAVAVSIGVVIGVLVTSYVWPYEARVELRKGLSDLLLNISWLYNRLVSVYSANLDRVNVIPPMEPRHKGLSEPRDLGRTTTFQERFQTPHDTSVVISTDMGIEKMNKEFMAIELSLQLQLLRLYALLEETPNEPRLKGKFPVGTYRDMLGSCQNILDRFLSMRLVITKDEWIESARRDFIIPVNKERREMVGNVLLYFYTIASALRLKTPLPPYLPPANDARLRLIQKIRQLPVVQNKVVMTEDNDERYIFFYAYALVMEDVIRELERLGHWSQDLFGVITPAAEFESWFTDDGTASLSLPPPRLPSSATREAPLSPYSDVDQPYQYPSSSEVPTRPPQRRSDSGQAILRLSNHSRHPDEVGSPTDPDAQSNPNYQSLQNSIVDRDGMFYFDPQDPFRDQPRNGDEGIDNGDQTKTPTTLQGSGGSQRSGRKFGSSNSLNSTTSALYNHQRQGSKASRNSHERRSSQGGRSYGTMPSIHGGNEQNRASTHSSRSSLRGAGSSTGTQLPSTNTVSSRSLRASISANRPVDEQSIFGGQIVQEPQQQEQLHRNEPGSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTF7</accession>
    <name>A0A9P6MTF7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="2">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">STUB1</name>
        <name evidence="10" type="ORF">BGZ80_011459</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010000923">
        <property type="protein sequence ID" value="KAG0012868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTF7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071218">
        <property type="term" value="P:cellular response to misfolded protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045862">
        <property type="term" value="P:positive regulation of proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006515">
        <property type="term" value="P:protein quality control for misfolded or incompletely synthesized proteins"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041312">
        <property type="entry name" value="CHIP_TPR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003613">
        <property type="entry name" value="Ubox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46803">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE CHIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46803:SF2">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE CHIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18391">
        <property type="entry name" value="CHIP_TPR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13414">
        <property type="entry name" value="TPR_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04564">
        <property type="entry name" value="U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00504">
        <property type="entry name" value="Ubox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51698">
        <property type="entry name" value="U_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="repeat" description="TPR" evidence="6">
        <location>
            <begin position="7"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="U-box" evidence="9">
        <location>
            <begin position="237"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="207"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="147"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0012868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="315" mass="36478" checksum="D3E98F8B9CD88783" modified="2023-09-13" version="1">MTSYLTAEQHKLKGNEYFKNKAYDDAIQEYSTAIVKDPKVAVYYCNRANCFLKLERFTNVVADCERVVELDPKSVKGYYFMGKAQLELGQPSEAYSRLKKSLDQRSSFIKDIVMIISEAKKQKWIEDERRKLSQVSETYHYLSGLVEQDIQRQLEALDKNASDYQENIAYLRSERDQRLQQLEILLQRAGTPDQYVKPHIQLDQSKAPLISPESSPQLPKVSGKQDSHQEASFQVREVPDYFLDKITFEFMHDPVISTKSGISYERSTLLEHFSYGRMFDPVAQVPLTEHDIVPNRALKEACDDFLSKNGWAVDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUL0</accession>
    <name>A0A9P6MUL0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_011128</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000857">
        <property type="protein sequence ID" value="KAG0013357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUL0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000286">
        <property type="entry name" value="PH-protein kinase domain containing protein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051707">
        <property type="entry name" value="PI-Interact_SigTrans_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14336">
        <property type="entry name" value="TANDEM PH DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="92"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="420"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="523"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="602"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="222"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="602"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="630"/>
            <end position="644"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0013357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="660" mass="71941" checksum="447065D6E6DF974F" modified="2023-09-13" version="1">MQVLPRLNEEIIKEDNNDNVETTSPTTFPTPTTAIASTTITSTNPSIIATTTTTTGEPNDIEDDSYDLCDDSDTEAPLGWKGVTKDTLQEGQIIKAGYLMKKGERLKIWKKKWFVLRTSKLAYYKDSKEYELLRITDIRDVHKAAEVPVKHKSGVFVILTPRRTVTVQAKDVAEMRDWVQAINQAKVQFDFTASSSDLESYAGSTAQLGCLQQDGNMDTMGTRPLQQQQQPQPTTRQEMILPRRQQHKPLSLSDPDLLDKREKSRIKGKGIALSTPTSATPQSPVGFPGSSVANILDRPTPRTGGPRAGPGLTLVTSTQAMQISSPSSPRMEQVHSTELPVGSFSSDQSNGANAVVPETPSSPGGYYSGGEAFWSNHDHNMSSGEEDVADDPSILEAGRLASEVNAPGSGIVTDEQLGSKLVRQGYLYKLGNKYKTWRKKWFVLRGDKLIYYKNTKEYQPHGIIPLSTIIDCLQMDPVSKSRQYCLRIVTVKRSFVCSAPDEDTLLQWLDALHVECDRVAHEAQQEEIADNQAHQQQGSGSLHDGHEDDDEQQAKQLGRTARLKLNLHSSLPRTRSKSGDGTGLFGSSANSTGAQIRKVLSLDSSGGTPLPSPSTTGERGGGGGDKRESLTSPNVTFQIPTISEASPGLPTPGTTVTFSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUZ5</accession>
    <name>A0A9P6MUZ5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_010917</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000814">
        <property type="protein sequence ID" value="KAG0013687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUZ5"/>
    <dbReference type="OrthoDB" id="10368864at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="19"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0013687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="162" mass="18172" checksum="C957E67D3FAE3E05" modified="2023-09-13" version="1">MPKAIKAPLASQGGSRRISVSSCSTGSNSNSNDNTVNVSTNNGIADARKWIVPGGLGISRYFSLVMYMNWHHWGFIQWSNSTLESMQSDQEEYLRSLNVLLATKEAPPQIKKRVKKILHKHDQEQFLRYARERAKRKSSEHAINATRRAIKAIVTAASDSDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MW64</accession>
    <name>A0A9P6MW64_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">NMA1</name>
        <name evidence="2" type="ORF">BGZ80_010370</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000714">
        <property type="protein sequence ID" value="KAG0014559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MW64"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000309">
        <property type="term" value="F:nicotinamide-nucleotide adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004515">
        <property type="term" value="F:nicotinate-nucleotide adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD+ biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051182">
        <property type="entry name" value="Euk_NMN_adenylyltrnsfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12039">
        <property type="entry name" value="NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12039:SF0">
        <property type="entry name" value="NICOTINAMIDE-NUCLEOTIDE ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cytidyltransferase-like" evidence="1">
        <location>
            <begin position="21"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0014559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="121" mass="13640" checksum="2F953E9570CA6921" modified="2023-09-13" version="1" fragment="single">MARDYVLENTNFEILAGYFSPVSDFYQKQGLAEAKHRVRMCELAVEKSSNWLMVDSWESLQTSYQRTAIVLDHFQHELNGPDGEGGIKLRNGQYKPIKIMLLAGGDLVQSFAAPDVWATAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MW98</accession>
    <name>A0A9P6MW98_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ketoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_009838</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000625">
        <property type="protein sequence ID" value="KAG0015480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MW98"/>
    <dbReference type="OrthoDB" id="1393670at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketoreductase" evidence="3">
        <location>
            <begin position="12"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0015480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="259" mass="27347" checksum="AF22C4F1D7A83BC6" modified="2023-09-13" version="1">MSVSTLSRFANKVVIVTGGASGIGQAVVRRFAAEGAIVTATDVNETGLIEGAEQVKRLATAGGRSSFVVGSVADEDSVKKIVQDVVDREGRLDALINVAGIIRSKSIIDTSLDQFMEPISTNLIGTFLFSREALPHLLKTKGNIVNTASTAAHYGHPFMAAYAASKGGVESMTKALAWEFLRQGVRVNAVAPGGIETPLSTNNQGNLADVDLTLFQRLIRPDYLWGKPDQVASIYALLASDDGGFMTGEIVKVDGGVHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWF0</accession>
    <name>A0A9P6MWF0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_009917</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000638">
        <property type="protein sequence ID" value="KAG0015325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWF0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0015325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="516" mass="58092" checksum="EAF9497C5E38D666" modified="2023-09-13" version="1">MDLPEIRYSVAEHLDSAQLAAAAAVCKSWNATFTPFLYSKVVWKVGDVAAKDKKKQSAFQAKSAHVREVEVYTTSGPKAPAISMGTFTCIESLEIHFQIYEPIHWAFILRLLRQNPELHTLKLDFCDCGDIPPEILKTLSKSCPKLKAFHTCNALISVKDMEHLLLTMCNQLEILIMDHVHFIDHTRDANHQHSQIKLSLPRQFLRMTDLRVEANISPTQQLELFKRCPQLVAMKVMLPDGRTHIPADLIYEIFGTCCPLVGKIGLECCSLSDAEFAKAIDLCRSRLTIATVFGTDFGPKAMQLLMERHAATLTLVNVTECHSVTSVMNLQILTSCPNLLKFHGSDLKAKDILGISDDAKAVTEQDLSLIQPQEWPCKSLRILDVYICGLHKKPAAWHRLIIQHIAKFKKLEELNISPSASSYGKAIRSNGESVDGLDLRLANGMDAMSDFKRLRALLCLNLRMKMGVEDVRWMTKAWPEMKNVFGVLNSDRRKEEVLLTILKSRGVFVRRGVSPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWS7</accession>
    <name>A0A9P6MWS7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">PABS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_009959</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the spermidine/spermine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000645">
        <property type="protein sequence ID" value="KAG0015245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWS7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006596">
        <property type="term" value="P:polyamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050562">
        <property type="entry name" value="FAD_mOase_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030374">
        <property type="entry name" value="PABS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF037959">
        <property type="entry name" value="MFS_SpdSyn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356:SF2">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356">
        <property type="entry name" value="FAD-DEPENDENT MONOOXYGENASE ASQG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01564">
        <property type="entry name" value="Spermine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51006">
        <property type="entry name" value="PABS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="489"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="533"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="586"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="628"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="655"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="domain" description="PABS" evidence="10">
        <location>
            <begin position="865"/>
            <end position="995"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="401"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="423"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="913"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0015245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1092" mass="120619" checksum="861256AB4C8E0561" modified="2023-09-13" version="1">MPSKSDRKCDVPPSSEQNSVPFSVHDWPNLSEMKILIVGAGLSGLLFATLCQRMGIQYDIFERSDGSRRSGGVMSINSGILPALEQLGIYEKLVESSYPVFCSNVIDEAIGLPPERIHYNKRVIQISEYIAGVSIRCSDKQEHHGTLLVGADGGYSHVRQCLYEDLSAKGLLPPEDSTGFKNPYTTLFGTTDPLPAEDFKDIGEGYSTFTLSIGKEPYCWTTFTVPGNRICWTVHKQVLEEQYQSMVFRKSNWGPETVDDMVNEVKHLATGYGATIGTLVSYTPKESIARVWAEDKVFNTWHHGRIVLIGDAVHKVFRSYDDDDDDDDDDDDDDDDNGVDTGLARAVNAMQDAVVLANCLYDLKSLSREQFDIAFQKYQDLRMPHVMEQYEASRRQAKFISNQVMKNQKREDRSGASGKGHAGEASDAASSAISSSVSHHSTSTTQRHYSSSSSTTSSKASAKNINDSADRTKAKAAAAARQPHSLTMLLELLLTVTRASLIILTPLVAGMVLRVSPSMMDPIYGNIFIEDHFLEYSLISAGVGVVLAMIYTFFSGSSKRTASSSSPEAVSIAAGLRKDARIRKGIVVCLDMCALFLASSFITTHAMFKHSGEFGPWRGPHLTQLFLAYPVLALLGSANTLACVLRSYERVHVRTWMSCVLIQIGSILGLTLVVYQMAPQGQSCPRIYTSAILVAIISGLHKTLTFTHGEVALPDEHLEGLRKPKTASSRASLAVGFIPLVLVLAMTAQNATRNPQCQAGVTKAHNPVSGNYTILARNESVTGWISVVDEHTTRHDLHIRVMRAGHSLIGGMYAETGDSIFGTFYIPEAVRLIKNREKSQPEVALQIGLGVGIASSSLIQRGVLMDVVEIDPVVADYASKYFDWPKPNELFIQDGRQFIKNAPEGKYDYVIHDVFTGGGVPPSLFSLEALHDIQRIMKPDGVLAMNMVGSEHPSKAQAFNSVRRTLHAAFKHVVGFKESPEEPDAYQNMVFFASQIPIEFDQYTPPPPPSQEEMEEMRQQGGHVNHALRPSVMRDWILSSFQDWPLSTPYDPSKGELILDRNNTLNGMQRLGAEDHWHAMRSLLPLDFWINY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWW8</accession>
    <name>A0A9P6MWW8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PWWP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_008850</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000495">
        <property type="protein sequence ID" value="KAG0016863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWW8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05162">
        <property type="entry name" value="PWWP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.10">
        <property type="entry name" value="Conserved domain common to transcription factors TFIIS, elongin A, CRSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052657">
        <property type="entry name" value="PDP_family_Arabidopsis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000313">
        <property type="entry name" value="PWWP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035441">
        <property type="entry name" value="TFIIS/LEDGF_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10688">
        <property type="entry name" value="PWWP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10688:SF5">
        <property type="entry name" value="PWWP DOMAIN-CONTAINING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00855">
        <property type="entry name" value="PWWP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00293">
        <property type="entry name" value="PWWP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47676">
        <property type="entry name" value="Conserved domain common to transcription factors TFIIS, elongin A, CRSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63748">
        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50812">
        <property type="entry name" value="PWWP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PWWP" evidence="2">
        <location>
            <begin position="8"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0016863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="429" mass="47088" checksum="E4BED75ED3664D2E" modified="2023-09-13" version="1">MTDNPYPVGTTVFAKLKGYPWWPARIESEDDLPENVGSKKPKQRPIWPVFFFGSYDYGWFGTSELKAFDPPSAEKAKSSLKKGNALRTALAEALDPSLVADRSTNGQGDYDEDGDEEQYEQETPARKKAAAKPKKTTKAEPAEKKRRSSTTEDQAVKRKPSKRSVPADEGEDEEESPKAKKRASVVPRSHLESDKRSVDDDISGADVSNGRTRKSEEDAGDSSDLRAKKKLRSGQPNERLLKLRHKLQKLLLVEGLSDEVLVQNLERADPILAEVEAFEIDLQLLKDTKIGRLMKKISALQFSQDPRRIVERSVKLIKQYKTMMEKAQENGEAASPSDKATEVTAPVETKLAVADQKLVAVEGVTSENVKPQAPNVSNHVSDVPPAPQATVVAAATIVETDTIVSTEKSTTMSSETTVVTSTSNEAAVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MX51</accession>
    <name>A0A9P6MX51_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">3-hydroxyisobutyryl-CoA hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">EHD3_2</name>
        <name evidence="13" type="ORF">BGZ80_009255</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Endosome membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000538">
        <property type="protein sequence ID" value="KAG0016383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MX51"/>
    <dbReference type="OrthoDB" id="1716625at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00052">
        <property type="entry name" value="EH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09913">
        <property type="entry name" value="EHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000147">
        <property type="entry name" value="EH domain-containing protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.268.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040990">
        <property type="entry name" value="DUF5600"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000261">
        <property type="entry name" value="EH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031692">
        <property type="entry name" value="EHD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030381">
        <property type="entry name" value="G_DYNAMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11216:SF31">
        <property type="entry name" value="AT21416P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11216">
        <property type="entry name" value="EH DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18150">
        <property type="entry name" value="DUF5600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12763">
        <property type="entry name" value="EH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16880">
        <property type="entry name" value="EHD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00027">
        <property type="entry name" value="EH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50031">
        <property type="entry name" value="EH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51718">
        <property type="entry name" value="G_DYNAMIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0967">Endosome</keyword>
    <keyword evidence="13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynamin-type G" evidence="12">
        <location>
            <begin position="149"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="EH" evidence="10">
        <location>
            <begin position="539"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="11">
        <location>
            <begin position="571"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="11"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="33"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="90"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0016383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="624" mass="69218" checksum="E3F8FEAE1B991C1B" modified="2023-09-13" version="1">MGYPDEKKTGSRPSSSGGPSAGNPNYYQEESMSRSSYSRHSNGGSSGGAGYNEGSPVLNRASISSNRAAPPLPSRQVSTIHRNGNGVGGSTSAHGTGIRGSTRSFASIKDDYKEVYRDLTHIYKHKIKPLETTYNFEGFHSAPLTDSDILAKPMVLLLGQYSTGKTTFIKHLIESDYPGSHIGVEPTTDRFVAVMNGSESRVIPGNAAAVSAELPFRGLDRFGQAFLTRFQVSQCPNSLLENMTLIDTPGILAGDKQRVERGYDFTKTIEWFAQRSDLILLFFDSYKLDISDEFKSSISALKGQEEKVRVILNKSDMVDQQQLMRVYGALMWSLGKVVQTPEVMRVYLGSFWLHRPPNVFEDCRQLLEKEQADLLKDLRDLPRNAAIRKVNEIVKRARLARVHAYIIGHLRKEMPAMFGKKTRQRELIQDLQGEFLKVQQLYSVPAGDFPNVAAFRQCLEAYKFENFAKISMPILKVAEEALSTDLPKIMSRFPQHANPLLELSQKNPFLGPPEEFNALNSNGSKNDIPPGYWHFSSVDKVAAQPIFDSLNPIEGKINGSSARPYLMSTGLSVDVLAKIWALADWTSDGYLSLEEFAVALHLVKAVETGGEAILPAKLPETMLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MX86</accession>
    <name>A0A9P6MX86_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">40S ribosomal protein S22</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPS22_2</name>
        <name evidence="6" type="synonym">RPS22_1</name>
        <name evidence="6" type="ORF">BGZ80_003062</name>
        <name evidence="5" type="ORF">BGZ80_009166</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000527">
        <property type="protein sequence ID" value="KAG0016508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JAAAID010000179">
        <property type="protein sequence ID" value="KAG0021078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MX86"/>
    <dbReference type="OrthoDB" id="10250260at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1370.30:FF:000001">
        <property type="entry name" value="40S ribosomal protein S15a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.10:FF:000002">
        <property type="entry name" value="40S ribosomal protein S15a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01302_A">
        <property type="entry name" value="Ribosomal_uS8_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000630">
        <property type="entry name" value="Ribosomal_uS8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047863">
        <property type="entry name" value="Ribosomal_uS8_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035987">
        <property type="entry name" value="Ribosomal_uS8_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003115">
        <property type="entry name" value="PRK04034.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11758">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S15A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00410">
        <property type="entry name" value="Ribosomal_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56047">
        <property type="entry name" value="Ribosomal protein S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00053">
        <property type="entry name" value="RIBOSOMAL_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0016508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0021078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="130" mass="14979" checksum="A05FF4827C1ACF85" modified="2023-09-13" version="1">MVRISVLNDCLNNINNAEKRGKRQVLIRPSSKVIIKFLSLMQKHGYIGEFEEIDDHRSGKIVVQLIGRINKTGVISPRFNIKLNEIEKWIARLLPSRQFGYIILTTSAGIMDHEEARRRHTGGKVLGYFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXT1</accession>
    <name>A0A9P6MXT1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Sel1 repeat family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007809</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000407">
        <property type="protein sequence ID" value="KAG0017882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXT1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0017882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="181" mass="20408" checksum="60A6453FE573BEB9" modified="2023-09-13" version="1">MHERGYGVTQSYSHAIDWYKKASSQGHIKAQYNLGVLYEKGYGVPQDYSKAGEWYQKAASYGHVSAQYNLGVVYHSGLGVAQDYFKAAEWYQKAAEQGHTRAQLNLDAVKIKNLSTNDILVPNMTEKYPQIFHVIYRDNTSGAITPLLKTIDIELQFGSKTEKHIVLWDDIKAASNDTLDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MY58</accession>
    <name>A0A9P6MY58_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_008980</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000507">
        <property type="protein sequence ID" value="KAG0016733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MY58"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0016733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="231" mass="25960" checksum="2A90D5746F7C2532" modified="2023-09-13" version="1">MLERRKQELYKSSYWTNNPKNQVQGPIPLSAQQTLYDVLISVDILSNSTYDQEQSDMEKPPETPVETTKPMQLTFAMNHSNADAIHNQFDFPTTTPEVALAPPLYPRVKWESLPTQTDLSLITIQRNSSGPIALSALQEPTQHLPSHTTDASLCHAIIRSGQVYSTTLSPSCIESPPDCRRTNETVLGPISPTEGRPPHIPSRCFYRPQDHRTGINPILKRLGTKLHKRIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MY76</accession>
    <name>A0A9P6MY76_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Raptor N-terminal CASPase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_008966</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat RAPTOR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000506">
        <property type="protein sequence ID" value="KAG0016739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MY76"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031931">
        <property type="term" value="C:TORC1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071230">
        <property type="term" value="P:cellular response to amino acid stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009267">
        <property type="term" value="P:cellular response to starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030307">
        <property type="term" value="P:positive regulation of cell growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010506">
        <property type="term" value="P:regulation of autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031929">
        <property type="term" value="P:TOR signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004083">
        <property type="entry name" value="Raptor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029347">
        <property type="entry name" value="Raptor_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12848">
        <property type="entry name" value="REGULATORY-ASSOCIATED PROTEIN OF MTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12848:SF16">
        <property type="entry name" value="REGULATORY-ASSOCIATED PROTEIN OF MTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14538">
        <property type="entry name" value="Raptor_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01547">
        <property type="entry name" value="YEAST176DUF"/>
    </dbReference>
    <dbReference type="SMART" id="SM01302">
        <property type="entry name" value="Raptor_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Raptor N-terminal CASPase-like" evidence="6">
        <location>
            <begin position="113"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="1198"/>
            <end position="1240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="794"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="860"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="16"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="37"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="794"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="807"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="865"/>
            <end position="895"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0016739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1261" mass="140529" checksum="7EFFC2CBA1227D1D" modified="2023-09-13" version="1">MRPRQSDNDNNEDARSTNSTLVNAGMNSANEQDDDAEPTHEPRNGYRRPEGGLGEDEDTWNSYRHGFDENELPSEHFYYMFYTDKRHEVTTGHNAEITLREWEPLQDWRMREKLKTISVALVLCLNIGIDPPDVVKTNPCAKLEAWIDPFVLPVPKSLENIGKALQAQYEVWQPRARYKAALDPSMEDTKKLCCVLRRNAKEERILFHYNGHGVPKPTSSGEIWVFNKNYTQYIPVSLLDLQSWLGSPCIYVYDCSAAGNILLSFNRFAEKRDLDAAKQAGSQPPGTIPSPPLRDCIQLAACGPDDTLPMNPDLPADIFTACLTTPIEIALHTIAWNVLSRDLFKTLFRQDLMVAALFRNFLLADRIMRSQKCTPMSSPALPPTHQHPMWDSWDLALDMCLAQLPALLQAEGSGSPIEYQASMFFAEQLMAFEVWLGHGSPTHEAPEQLAIVLQVLLSQVHRLRALLLLSQFLDLGPWAVNHALAVGISPYVLKLLQSPAADLKPVLVFIWARLLAVDRSFQNDLLKDNGFVYFVGILGVNAGMPLRNVSEHRAMCAFILATFCRDFPQGQQACLKQQVIQYCLTHVADGDHLLRQWACLCIGQLWKNYNEAKSVGLQTGAHERLTQLLSDHIPEVRAAAMWSLGTFISNLDQNEQVIQLQNNLAMSALVATTDASPIVRKELVIFLSSMVFDHVDVFVVVASELLASEQQLLGSKNDSKTKHLEDRQDKLGQHAVYAVIWKALLCLSVDSNRGVALAASKLVDYVNFQVLSGPVAQDLIPLLQQHALRSQSMSSSSMNSIHQAASPQSATDRSYASTTLGHRTASKMANTLKRSASLAVTLKNYIPGYSSNQASGLETSGYVGKSSQDAGHQSTQDSRQMNGGANGPTRTTRSNVPRPRSVHGDAGYVQAQASVSYPHISQSNGSAAMNGSMDSNNPESRPVLESVFYDWCCEYFLEPQMKGVEGEEPGSVNYNERLWRRVRNEKIIYECHPLREQAGIGKWDSTIQTMNNESAAMHLTMHSYEPHMVIADDKRNISVWNWKEGQLLNRFSNSNPRGTSITSVKYINEEDVAMLMVASGEGVVRLYRKYEEPNQTDIVTSWRVLTDMLPSSKSTGTIADWQQGRGALLVGGDARVIRVWDAARELCISDIPTRSGAPVTSITSDQVAGNIFVVGFGDGAVRVYDRRQPQHDAMVMTWKKHKSWIQNVRMQRGGFRELISGSVDGTVKVWDVRHQESLSTIQAHGPISALDLHNHAPVLAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYF2</accession>
    <name>A0A9P6MYF2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_007387</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MAK10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000377">
        <property type="protein sequence ID" value="KAG0018264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYF2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031417">
        <property type="term" value="C:NatC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057983">
        <property type="entry name" value="NAA35-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007244">
        <property type="entry name" value="Naa35_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057982">
        <property type="entry name" value="TPR_NAA35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21373">
        <property type="entry name" value="GLUCOSE REPRESSIBLE PROTEIN MAK10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21373:SF0">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 35, NATC AUXILIARY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04112">
        <property type="entry name" value="Mak10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25789">
        <property type="entry name" value="TPR_NAA35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAA35-like N-terminal" evidence="5">
        <location>
            <begin position="47"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="NAA35-like TPR repeats" evidence="6">
        <location>
            <begin position="321"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="391"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="569"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="391"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="572"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="584"/>
            <end position="600"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF25789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0018264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="820" mass="93045" checksum="CEA14D7E93C047D6" modified="2023-09-13" version="1">MDQDASDKSTQRIASKTAQLNLNSGAVYPYEDVTSLLESATKDLKTGQLIQVDSFSLFDAMCAIVIMDPKMDTGIIVEELPQYDINRLLNPKEFIWVFDNILVGQMTWLSGHALSQTLFTSCYILRLFEINLEDEPPVSSSNAQEPYPPKEFVTLVLKSCTLAIAKSCALIWNEMKKGQVYEEEDFMTNKFGVTLYENFPTSSLVMMLDQAEYWMEELGKQWVDSHYGSEANDIHRVAPKCSQFPQAITLLVNIRKHVQEIKSTSALGSQVEGAFDHTVHRKLVTYTPPRAIALLTLEETFTQLDQMCADLEFIARALPFPDATNLVNFFIHFGAQKPAPGAFPRSILQTALYDNQVIMGSTMIQEVIRDSIQELVSPAAWIFEIFNESPTKSDVTNSSSLEPIPEHAEDDIPAQKRQVQTKLVLFIDKAIKPFVDTLQIAGQNSSRQRRNLRKIVQLWENLQEDAEFFDEEIHAVLDRIRAQQEPETIESVDSDISHRPFYFVSWVYHMKLWVMEWLLLLGFELELYSTFEYSMIYGYIDCVLGAHAQHLRRVQTVVESESLANNKEGSILKKKKKKKKKPSSDSGIVQSSADAESAETTPASVTPAAILTPAIRATQDLVTIRLQLARGIFLILAALTRVGHLSTTPQHLASHGLNDLETLYRHRFKAFHHLSSPEAMTYENYLHRLDCEGLDAWQILEYAGEFFSQAKAGLDRLQSFSARDARVDLCEDAWRKDIKSMIKICIANKLAIAGLQKDARVLEQKEFTAESQKRAAAILKRPSKGRDSKQTESRFSFKASVRKPQFEWKYHSLWPVITLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYN6</accession>
    <name>A0A9P6MYN6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Regulator of ime2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">RIM11_2</name>
        <name evidence="10" type="ORF">BGZ80_008427</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000456">
        <property type="protein sequence ID" value="KAG0017303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYN6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004712">
        <property type="term" value="F:protein serine/threonine/tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14137">
        <property type="entry name" value="STKc_GSK3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000055">
        <property type="entry name" value="Glycogen synthase kinase-3 beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000009">
        <property type="entry name" value="Glycogen synthase kinase-3 beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050591">
        <property type="entry name" value="GSK-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039192">
        <property type="entry name" value="STKc_GSK3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24057">
        <property type="entry name" value="GLYCOGEN SYNTHASE KINASE-3 ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24057:SF0">
        <property type="entry name" value="PROTEIN KINASE SHAGGY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="39"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0017303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="379" mass="42924" checksum="2F26972A40626BE4" modified="2023-09-13" version="1" fragment="single">MSSAAPINGIKISGESDPTKVIKVMANDGKTGEPFELAYNNCKVIGNGSFGVVFQAKLLATGDDAAIKKVLQDKRFKNRELQIMRLVSHPNIVDLKAFFYSNGEKKDEVFLNLVLEYIPETVYRASRHYSKIKQTMPMLQIKLYMYQLFRSLAYIHALGICHRDIKPQNLLLNPVTGILKLCDFGSAKILVAGEPNVSYICSRYYRAPELIFGATNYTTNIDVWSTGCVMAELMLGQPLFPGESGIDQLVEIIKVLGTPSREQIKTMNPNYMEHKFPQIKPHPFNKIFRSRTPPEALELISRLLEYTPTRRFTPIEAMVHPFFDELRNPETKLPNGKDLPPLFNFTPLELSIRPDLIPMLVPHHAEAELSSRGIDVHNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZ12</accession>
    <name>A0A9P6MZ12_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidase A1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_006124</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000301">
        <property type="protein sequence ID" value="KAG0019231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZ12"/>
    <dbReference type="OrthoDB" id="771136at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF75">
        <property type="entry name" value="ENDOPEPTIDASE (CTSD), PUTATIVE (AFU_ORTHOLOGUE AFUA_4G07040)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040295461" description="Peptidase A1 domain-containing protein" evidence="4">
        <location>
            <begin position="22"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="5">
        <location>
            <begin position="1"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0019231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="347" mass="35965" checksum="B01F32BEC005DD64" modified="2023-09-13" version="1">MLMSTSLSAAIALACISITAAAGVITVPMTGLVRPEHQNAVSLTKRYLQKRALTSTSPLTSASNDVMYNANVPANAPFLNTLKNTNALTEPVIGIWLKDTSSINSTTAPGGEITFGGVDSTRFVGNITYINCDPISPWTIPLTSFSVSGKTYLTTGALATIDTGTTAMLLPEAVADAINSGIPGSIKMATPQEDISWIIPCNGTTPVSFTFGTFTATIPYSSIAMNNIKFQSQQTGAVYCASVAMYPIGRITSMKEWLLGDALLKNVYSVYDFGTNAATGGRIGFAQLVGSNSSSNVGNNSNSTDIGNGYVGSGTSSSAESVSSSIHSMSRVLQALAAVAGIAVFTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZ95</accession>
    <name>A0A9P6MZ95_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_005827</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000287">
        <property type="protein sequence ID" value="KAG0019429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZ95"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="87"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="418"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="469"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="520"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="263"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="9"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="112"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="130"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="151"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="183"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="437"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="476"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="532"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0019429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="643" mass="71413" checksum="9641EB791E74F5B3" modified="2023-09-13" version="1">MLSSHKKSASSGGSSTSNRSININSNRNSYTNASSSSNNATNTNNTSGNRVENSRNHDNYLIESNPQSMSARLSAGMVPYFIPPQPQTSLGYANPDRGSPLDPTMITPPMSPTENSFAFPSSTIEGRFASSSSHHYSHSSNDQHSKTPNITSSSATSSLTGPSSTSATATGVSPRPLSFHWDDYEDFDEDDEDDEDQDSEDSQDEVDGHEDNSMASKSAYHRRFEGHHSVVRSRSAYGRGRKGDRQDFEETYDSFRHGIGLSVSDMSDELAKARSKMTRASRAMKNMEQELEAMQRSIDESKASNASTRTAIEENFWRLECLALTIEKDRQDSMKRIQAVGRECSEAVEAVTNWEVRIDWLEKKVDNTSEYVSELVLSEQECMSFIKMIIQQNQRYAMPAISRATERNIKLMAPPRLKEIAPPGHQAPQLSRQSQPQPLPQPRPQPPPQPMQPQPSVRHIPISWLLDPLMPPKPPEILERDEQRTDDSTMEMKATIEPPAELWRDFSRLTTAFETGQARTPFSPFQRTRSRSTGQGALSTSGLGSSSGSNGVHNGSMFKATMARRPQVENLSPMPKILPPVIATNALPGVRRRSQNLSHFPMHSWLQVQFNKTMTVPGLGQGGSKKKTTVLGFKPITIFQTTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZL8</accession>
    <name>A0A9P6MZL8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_007088</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the type 2 lipid phosphate phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000357">
        <property type="protein sequence ID" value="KAG0018506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZL8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042392">
        <property type="term" value="F:sphingosine-1-phosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.144.10">
        <property type="entry name" value="Phosphatidic acid phosphatase type 2/haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="PAP2/HPO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="PAP2/HPO_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14969:SF28">
        <property type="entry name" value="DIHYDROSPHINGOSINE 1-PHOSPHATE PHOSPHATASE LCB3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14969">
        <property type="entry name" value="SPHINGOSINE-1-PHOSPHATE PHOSPHOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="Acid phosphatase/Vanadium-dependent haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="15"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="338"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatidic acid phosphatase type 2/haloperoxidase" evidence="9">
        <location>
            <begin position="13"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0018506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="368" mass="40484" checksum="97BF55BD79ADC406" modified="2023-09-13" version="1">MTTDPASWSPYTRELAILGLIIYAISIIYGRLYCGMHSITDCVGGTLIGISIWAIHWTFRESFEYYATSPIIWVPFFVSAMGIFLVSIMPDPVDDCPCFDDCVAFIAVIMGVSPASIHFASTSYSSNYPVPGTIPYSSDLGIVKSILRLVLGVGTLFVWRLVAKKLLYVLLPPVYKLFSLPYRPHFIPASTYNTLSAYPIGKVPSVIDLPSMSGSIENIGLQSTMDVHEKFSQAAAAAQAQSEEYDGISIGLRSRKGQPTLEENGLDEKSWLLYEQQHHHERDISVLSNTTTECGDANEPEKHQYIGGSLEDQAEALLRVERMNPRKSRFDVDIVSKLVVYAGIGALAVDGIPILFALFGLGAEPVRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZW4</accession>
    <name>A0A9P6MZW4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_007045</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the IFI6/IFI27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000354">
        <property type="protein sequence ID" value="KAG0018537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZW4"/>
    <dbReference type="OrthoDB" id="2448769at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd17039">
        <property type="entry name" value="Ubl_ubiquitin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009311">
        <property type="entry name" value="IFI6/IFI27-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038213">
        <property type="entry name" value="IFI6/IFI27-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019956">
        <property type="entry name" value="Ubiquitin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16932">
        <property type="entry name" value="INTERFERON ALPHA-INDUCIBLE PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16932:SF18">
        <property type="entry name" value="INTERFERON, ALPHA-INDUCIBLE PROTEIN 27-LIKE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06140">
        <property type="entry name" value="Ifi-6-16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00348">
        <property type="entry name" value="UBIQUITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-like" evidence="7">
        <location>
            <begin position="102"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0018537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="187" mass="19054" checksum="8ACB7F53C674523A" modified="2023-09-13" version="1">MQSDDKTAFALFSTIISTAAAPFVFVNGVAAAGFGSAGIAAGSPAAAFMSSYGGAVSSGSLCATLQSIGAAGLGLPGIFLAASVRAAIGAGLSFILLANSPILVVIVNKEGQALELKIRPRDSIAEVKSKIRDLSGISPSLQILQFSGITLEDNKKVHNYNIKDGSVIFLITKIEVAMMLVAKIAPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N095</accession>
    <name>A0A9P6N095_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004254</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000219">
        <property type="protein sequence ID" value="KAG0020403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N095"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="16"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0020403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="533" mass="58480" checksum="2D5DB0127299C4A5" modified="2023-09-13" version="1">MSSFSNLPSSITAATSDPDSVSISISSSSPTSSVLLPSFTPSSSSSPSSNVRNSISFAARDPIAVSVTGDRDTIANLNSNDRPTEVGHRNPSNGGTEADDRIHFRLLNNIYFSASARQSRLDDDLGMDLTAISNGSERLLNMNRENSFMMVEDRITGENGMGYGDSGPRTSMFTDQGEEFASIAVRSQSDHPESIDDEDDGDDNGADQVTENRRLHNRGDMSIDLEHSSSSISNLERPRHAQLSPRSAAALTSMFSDGRTSWPQPILNSSISSDLIALSEGRTGHEYNNNPYFRRPAPFNPVREIRGSLDNVMGADASRSRSTSTQYDTVRHDYNSQIYLHRSGTGSHGNCGERTPVSVNEAQGDVWPLRFEIRSNNINICLKLAEPHQTFVLTQFRAKAPTTGFTAPCKEGLIFVSHEPIPLEKTAIFDNMTRERYDEYMQGLNQGPTFGQMLRNYGSKADALIPAAFFQMEGPDETCTLDLTPNRSGRYVIIKLLRSKCTNPLQRPENIDLQYLGLIGYTGARSFASGGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0I6</accession>
    <name>A0A9P6N0I6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fucosyltransferase</fullName>
            <ecNumber evidence="5">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">FUT11</name>
        <name evidence="7" type="ORF">BGZ80_005698</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Golgi apparatus</location>
            <location evidence="5">Golgi stack membrane</location>
            <topology evidence="5">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the glycosyltransferase 10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="5"/>
    <dbReference type="EMBL" id="JAAAID010000280">
        <property type="protein sequence ID" value="KAG0019520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0I6"/>
    <dbReference type="OrthoDB" id="427096at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032580">
        <property type="term" value="C:Golgi cisterna membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046920">
        <property type="term" value="F:alpha-(1-&gt;3)-fucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11660">
        <property type="entry name" value="Glycosyl transferase family 10, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055270">
        <property type="entry name" value="Glyco_tran_10_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001503">
        <property type="entry name" value="Glyco_trans_10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038577">
        <property type="entry name" value="GT10-like_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11929">
        <property type="entry name" value="ALPHA- 1,3 -FUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11929:SF194">
        <property type="entry name" value="ALPHA-(1,3)-FUCOSYLTRANSFERASE 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00852">
        <property type="entry name" value="Glyco_transf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="18"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="domain" description="Fucosyltransferase C-terminal" evidence="6">
        <location>
            <begin position="303"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0019520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="472" mass="54519" checksum="A46BDD137194EF43" modified="2023-09-13" version="1">MINLCSSVAISKRSLRQLVAVALAGVIIVWLMFIQLYSKGVVEHIVDNGTQMEADQSNPVHFSEQTDADFYTDPYQLKDICNKLPETPKHPRGILISHKTSAEPLKIFIWRQMTYMDPQTDWRKESLTLCPFPPELQPFFDFIRASHVYGDQAVNLAQWEQGFAPCFFFNKNVPEWQKNQINTCGSSNLKYITTSNYTEFRDADIIYMDYPFYNYMAGKAPFWDVRRLPPRISHQRWVLEYGRESIANYPHVALPSFLQQFDLTMGAPAPLFDVPYPLLPVSEEMARRYTEVKPAFPVDKKPDNYVAFVISNCQPRNDRNELIADLIKKIGAHSYGKCQNNRKMPDDETTKGRPWEEVKQEVLAQYPYTLVVENSNCVGYVTEKIYDALAAGVIPLYEGASDIADYVPKGSYVPLENFKNTDELVKFMKEADRSEFYKWKEEIKADPSKFCKSCHQGKEPLECRILNHVHFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0Q1</accession>
    <name>A0A9P6N0Q1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">RuvB-like helicase</fullName>
            <ecNumber evidence="15">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">RUVBL1</name>
        <name evidence="17" type="ORF">BGZ80_003589</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14 15">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 15">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the RuvB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="15"/>
    <dbReference type="EMBL" id="JAAAID010000196">
        <property type="protein sequence ID" value="KAG0020793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0Q1"/>
    <dbReference type="OrthoDB" id="10060499at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031011">
        <property type="term" value="C:Ino80 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000812">
        <property type="term" value="C:Swr1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000010">
        <property type="entry name" value="RuvB-like helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.360:FF:000001">
        <property type="entry name" value="RuvB-like helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.360">
        <property type="entry name" value="RuvB-like helicase, domain II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027238">
        <property type="entry name" value="RuvB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041048">
        <property type="entry name" value="RuvB-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042487">
        <property type="entry name" value="RuvBL1/2_DNA/RNA_bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010339">
        <property type="entry name" value="TIP49_P-loop"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11093">
        <property type="entry name" value="RUVB-RELATED REPTIN AND PONTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06068">
        <property type="entry name" value="TIP49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17856">
        <property type="entry name" value="TIP49_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0010">Activator</keyword>
    <keyword evidence="7 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 15" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="4 15" id="KW-0227">DNA damage</keyword>
    <keyword evidence="12 15" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 15" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13 15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 15" id="KW-0804">Transcription</keyword>
    <keyword evidence="9 15" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="16">
        <location>
            <begin position="61"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU363048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0020793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="455" mass="50169" checksum="0678ABD4B66E366F" modified="2023-09-13" version="1">MRIAEVKNSREQRIAAHSHIKGLGLRDDGYAEPIASGFVGQEQAREACGVVVDLIKSKKMSGRALLFAGAPGTGKTAIALAISQELGPKVPFCPMVGSEVFSSEIKKTEVLMENFRRAIGLRIKETKEVYEGEITELTPEETENPLGGYGKTISHVLIGLKTVKGTKQLKLDPSIYESIQKEKVTVGDVVYIEANTGAVKRVGRSDAYATEFDLEAEEYVPLPKGEVHKKKELIQDVTLHDLDVANARPQGGQDVMSMMGQFMKPKKTEITDKLRKEINKVVNKYIDQGIAELVPGVLFIDEVHMLDIECFTYLNRALESTLSPIVVFATNRGMCAIRGTEDITSPHGIPVDLLDRLLIIRTLPYTLEEIRVIITIRAKTEGLTVQDEALNYLADVGLKTSLRYSIQLLAPANVMAKINGRDEIFKGDVEEAGDLFLDSKRSAKIVTEESHGFIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0T1</accession>
    <name>A0A9P6N0T1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_004938</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000247">
        <property type="protein sequence ID" value="KAG0019993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0T1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006600">
        <property type="entry name" value="HTH_CenpB_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007889">
        <property type="entry name" value="HTH_Psq"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050231">
        <property type="entry name" value="Iron_ascorbate_oxido_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47990">
        <property type="entry name" value="2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04218">
        <property type="entry name" value="CENP-B_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51253">
        <property type="entry name" value="HTH_CENPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="5">
        <location>
            <begin position="158"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="HTH CENPB-type" evidence="4">
        <location>
            <begin position="621"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="326"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="512"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="328"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="514"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="551"/>
            <end position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0019993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1044" mass="119698" checksum="CA099D6C6F845EA7" modified="2023-09-13" version="1">MSNLSTASANVTIPVIDFSLFVSDPEECARQVGEASQNIGFFYLKNHGISQSLIDDMFDQSEMFFQQPVQVKGRRLIGPDNIGYSPMKSETLDPEHQTQGDLKEAYNIVKFSLEDDSTSNFVRGDKAEQEKVGSFFKVPQEAGGSHYFDKSHMWEAHSGTTLRFLHYPKQSGDPHTPLAGSHTDYGSITLLMQKDIAGLEVQASRIHKDVPWVAAPVIPNTILVNIADHLQMWTNGLLKSTMHRVMYNPQQLHSSRYSIACFIHANDSTRLDPIPSPLITQEMRAEAVEFEEGRNMTAGEYLAWRLNRSYNYDHHLEEEDSADLLTGSVPTESNSLNCLPQQSETSQDTPTDDAFARPFVYQHYQQQDSPQPDPITTAAQQYVLYPVVENNGYIMSIPQNLYIPTSLPLLSSNTTYETQFSFTRDAEHYDSQPLQQPGLSNFNHMLSIYSNFDFPYSPGPETIPSSDSDEWSMSYAQNGNLWPEAALEGTSQQQQSEVLYDFLKDTVGLTQHAYEPDPQRVERSPSVDSSEEEEPYMVDGRKSNRRTRKQPKSDEKRTRKALSLHEKLDIIRYRWQNPSVSIAAIARIKNVPRTTVHGIIRDQEEIIKKAADPWLEHRMTDTYRIVKRPFRILELLLQRWICDLNSRGISLSDLKITSQAFEIYRMLNYVLSYPLIPHKFTSVWLRKFKEQNRYYLEAPIYDTPGVDSCSLEELLQEIRSYPFNDIYLCGETIRHSTRVVVSNCYDGMIIDPDHEDLTGPGFHEWLREFDGTLGRNALLLVNEPLWELYKSSTSSLQHIKVLKVPTKYNILYPITTNTIKAFKANYLRLLASLWSFAEASAHMPLITLIELKLGFVLSAWRETKDKINLQELFKEMIYGDRNAESGSLTYEKSVEKELISAFKLTFHISDESQLKYQCSQDEDTGPTASLFNHLREIKRNPEYSEWFRSAYTPEREPPFCLERLAVQWSDVEACQRMQLVFLSARSLLEFTQEQLESYAGCSPLAACGGGYEVVIYNNDRKPHELTHPMAIKKEVHIELPRSDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0Y6</accession>
    <name>A0A9P6N0Y6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Galactose metabolism- protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">GAL83</name>
        <name evidence="6" type="ORF">BGZ80_003442</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the 5'-AMP-activated protein kinase beta subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000191">
        <property type="protein sequence ID" value="KAG0020870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0Y6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031588">
        <property type="term" value="C:nucleotide-activated protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02859">
        <property type="entry name" value="E_set_AMPKbeta_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000562">
        <property type="entry name" value="Snf1 kinase complex beta-subunit Gal83"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.250.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032640">
        <property type="entry name" value="AMPK1_CBM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006828">
        <property type="entry name" value="ASC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037256">
        <property type="entry name" value="ASC_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050827">
        <property type="entry name" value="CRP1_MDG1_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10343">
        <property type="entry name" value="5'-AMP-ACTIVATED PROTEIN KINASE , BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10343:SF84">
        <property type="entry name" value="5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16561">
        <property type="entry name" value="AMPK1_CBM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04739">
        <property type="entry name" value="AMPKBI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01010">
        <property type="entry name" value="AMPKBI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160219">
        <property type="entry name" value="AMPKBI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Association with the SNF1 complex (ASC)" evidence="5">
        <location>
            <begin position="324"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="122"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="310"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="25"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="323"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="341"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="361"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0020870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="473" mass="51456" checksum="A2759C8220375B97" modified="2023-09-13" version="1">MGNTPSNIGDGNSEPGAVESITFTNNHYQKQQNQQYHNRQHDNYTHQRHYSSPNAFPTSLGPQDSINPSTIPIAPIPVDGPQRPRFPYVKEQYINESPAGSSPLSSDSSYPIVAGEEHSLGDKHFQQRRTHQHQQPQKSSLPGGGPRRRASSLASGQVYGQYADSYNEQVLLATAAHQDKIEQQRLQQQAMEGRASYRNSARVSRAFDTLDPLKSLDDQNTDLADDGHVPTIITWSQGGNNVYVTGTFNNWKQKVRLNKSTSDFTTILNLPPGTHRIKFIVDDEWKCSTELSAATDAEGNLVNFLEVADEEQDELEGGHDSPINGSPVGSYTDQIPLYAQSGGSSPASPTGSDAVLPLTAVNSEANGNSASSNVSNGRSRSGSTTSSSSSSKFMHANSISNDPPPALPPHLEKVILNNVPSKEDNSVLPVPNHVVLNHLYACSVKEGVLSISVTARYRKKYITTVFIKPVVTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1H5</accession>
    <name>A0A9P6N1H5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Dolichol phosphate-mannose biosynthesis regulatory protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_003001</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the dolichol-phosphate mannose (DPM) synthase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Endoplasmic reticulum membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the DPM2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000177">
        <property type="protein sequence ID" value="KAG0021119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1H5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033185">
        <property type="term" value="C:dolichol-phosphate-mannose synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030234">
        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0180047">
        <property type="term" value="P:dolichol phosphate mannose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009914">
        <property type="entry name" value="DPM2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15039">
        <property type="entry name" value="DOLICHOL PHOSPHATE-MANNOSE BIOSYNTHESIS REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15039:SF11">
        <property type="entry name" value="DOLICHOL PHOSPHATE-MANNOSE BIOSYNTHESIS REGULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07297">
        <property type="entry name" value="DPM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="46"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0021119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="80" mass="9070" checksum="0B0AC78CE4438AF6" modified="2023-09-13" version="1">MASGQDKLVGASLLTFSTVVFVYYTLWAIVMTYFLHAYFPPREYAIRIPCVLLVFGLTVILSFLSMIMIKSKKKVEKKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N272</accession>
    <name>A0A9P6N272_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Translocator protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_000273</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TspO/BZRP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000105">
        <property type="protein sequence ID" value="KAG0022434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N272"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033013">
        <property type="term" value="P:tetrapyrrole metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd15904">
        <property type="entry name" value="TSPO_MBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1260.100:FF:000001">
        <property type="entry name" value="translocator protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.100">
        <property type="entry name" value="TspO/MBR protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038330">
        <property type="entry name" value="TspO/MBR-related_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004307">
        <property type="entry name" value="TspO_MBR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10057">
        <property type="entry name" value="PERIPHERAL-TYPE BENZODIAZEPINE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10057:SF0">
        <property type="entry name" value="TRANSLOCATOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03073">
        <property type="entry name" value="TspO_MBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="126"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="151"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0022434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="230" mass="25007" checksum="757F209A8480F541" modified="2023-09-13" version="1">MSYNDLHQACQSINTHLARYPALAVGLPLIGGFLSAVPSHRHIKNYYASLNKPSWAPPSGCFAPTWTILYLSLGYASHLVALHTSPTTLSSLRAPARTGLGYYGLSLALGFAWSPIMFWHDMIGAALVTIGGVTASSVAMSYYFFKVDELAGYLTIPYVAWLGYASALNYDVWIKNAKGPAVDKARKLGKDVNDAAKHAKHEIEDAAKLMKEDTEKAAKKAADKVDAERK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2Q2</accession>
    <name>A0A9P6N2Q2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Basic helix-loop-helix protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">CBF1_1</name>
        <name evidence="4" type="ORF">BGZ80_002106</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000151">
        <property type="protein sequence ID" value="KAG0021584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N2Q2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47787">
        <property type="entry name" value="CENTROMERE-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47787:SF1">
        <property type="entry name" value="CENTROMERE-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BHLH" evidence="3">
        <location>
            <begin position="148"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="76"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="125"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="224"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="81"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0021584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="265" mass="29609" checksum="112A52038A499748" modified="2023-09-13" version="1">MTSSEIHVQEVLNNLVSATNSIKRDGIDNLDESFTAAIATAAQAQAQAQAQTSAQQAQEQHDHHQVNQEELERIAQEHQHQTQTQEQGQDSQAEQSNLSAPANENSVIHVNALDAGNSSTLATVPITTVSPAPPSAKPVTGSEEWHKMRRDNHKEVERRRRENINAGINDLASVIPNPDKNKGAILRQAVKYIHTIQEAQQKAVADSEALASVQFERDRALLEKNMAQNQLHTLIAENDQLKRDYEALRKEFEELEESKKRQRTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3J8</accession>
    <name>A0A9P6N3J8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Sulfide:quinone oxidoreductase, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BGZ80_009668</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the SQRD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000060">
        <property type="protein sequence ID" value="KAG0023356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3J8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070224">
        <property type="term" value="F:sulfide:quinone oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070221">
        <property type="term" value="P:sulfide oxidation, using sulfide:quinone oxidoreductase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000034">
        <property type="entry name" value="sulfide:quinone oxidoreductase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015904">
        <property type="entry name" value="Sulphide_quinone_reductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10632">
        <property type="entry name" value="SULFIDE:QUINONE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10632:SF2">
        <property type="entry name" value="SULFIDE:QUINONE OXIDOREDUCTASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0874">Quinone</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="11">
        <location>
            <begin position="47"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00060891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00070160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0023356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="454" mass="49680" checksum="01117BF6B3B54F9B" modified="2023-09-13" version="1">MVFPSLTPLSSVARIGVRSSAFQSRRFLAQAVSATPKSQDQTKASSYKVVVVGGGSAGISVASTLAETLGDKAVAVIEPSDVHYYQPLWTFVGAGLKTFDESKMPMSEVIPEKAQWIKDSVASFSPNQNTVVLANGESISYDYLVVAAGIQVNWGKIKNLPQTLGKNGVTSNYSSDSVEKTDEFIKAFKGGNALFTMPSTPIKCAGAPQKIMYLAEEQWRKAGIRSQTDIKYFTGLGKIFAIDKYANELLKVCKSRNLNVNYFTDLAEIKPESREAVFNVLGGEAKGTQLTLPYDFLHVTPPMGAPDFIKGSPLANGDGWVDIDKETLRHNKFSNVYALGDCSSLPTSKTAAAITAQSAVLKNNLLGDIFGDKQVAKYDEYTSCPLITGSETLILAEFSGYSGQPQETFPFDQSKERYSTYLLTKEIIPEIYWKYMMKGNWDGPAKFRKWFGTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3U9</accession>
    <name>A0A9P6N3U9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Elongation of fatty acids protein</fullName>
            <ecNumber evidence="10">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_005235</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>an acyl-CoA + malonyl-CoA + H(+) = a 3-oxoacyl-CoA + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:50252"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:50253"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the ELO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="10"/>
    <dbReference type="EMBL" id="JAAAID010000026">
        <property type="protein sequence ID" value="KAG0024197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3U9"/>
    <dbReference type="OrthoDB" id="10259681at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009922">
        <property type="term" value="F:fatty acid elongase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034625">
        <property type="term" value="P:fatty acid elongation, monounsaturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034626">
        <property type="term" value="P:fatty acid elongation, polyunsaturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019367">
        <property type="term" value="P:fatty acid elongation, saturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030148">
        <property type="term" value="P:sphingolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042761">
        <property type="term" value="P:very long-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030457">
        <property type="entry name" value="ELO_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002076">
        <property type="entry name" value="ELO_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157:SF126">
        <property type="entry name" value="ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157">
        <property type="entry name" value="FATTY ACID ACYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01151">
        <property type="entry name" value="ELO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01188">
        <property type="entry name" value="ELO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5 10" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7 10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0024197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="167" mass="20101" checksum="19235194C6BC2186" modified="2023-09-13" version="1">MAKMIWLFYFSKILEFIDTMIMVVKKNNRQISFLHVYHHSSIFMIWWLVTFCAPNGEAYFSAALNSFIHVIMYGYYFLSALGFKQVSFIKFYITRSQMTQFCMMSIQSSWDMYAMKFLGRQGYPFFITALLWFYMWTMLGLFYNFYRKNAKLAKEAKLAKEKAKKLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N435</accession>
    <name>A0A9P6N435_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CUE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_007431</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000038">
        <property type="protein sequence ID" value="KAG0023900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N435"/>
    <dbReference type="OrthoDB" id="272778at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003892">
        <property type="entry name" value="CUE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02845">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51140">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBA" evidence="1">
        <location>
            <begin position="59"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="CUE" evidence="2">
        <location>
            <begin position="60"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0023900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="111" mass="11814" checksum="3DD0F3A80ADEDA4F" modified="2023-09-13" version="1">MRLAERFLLPIFSSSPAIRSTATTFENRSSSRPSGRPAMREYLDVLSTGGAPQGGTPRPPSEEQIATLQAIFPAATRDQAIAALNSANNNLDGAVQYLLDNQPNTPTVPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N437</accession>
    <name>A0A9P6N437_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mo25 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">MO25</name>
        <name evidence="2" type="ORF">BGZ80_002765</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Mo25 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000017">
        <property type="protein sequence ID" value="KAG0024451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N437"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043539">
        <property type="term" value="F:protein serine/threonine kinase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000257">
        <property type="entry name" value="Conidiophore development protein hymA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013878">
        <property type="entry name" value="Mo25"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10182">
        <property type="entry name" value="CALCIUM-BINDING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10182:SF3">
        <property type="entry name" value="PROTEIN MO25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08569">
        <property type="entry name" value="Mo25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0024451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="295" mass="34449" checksum="5B5F454B824ABBA9" modified="2023-09-13" version="1" fragment="single">ATEDISKILVSVKTMLYGDSENDPVPETVAQLAQEVYSNNLLQLLVDNIAKFEFEAKKDVAQIFNNLLRRHIGSRSPTVEYLCTRDQILFTLIHGYENQEIALNCGMILRECLRHEVLTKIILNSQQVYKFFDYVEMNTFDIASDAFATFKEILTRHKTLVAEFLERNYDVFFDKYTQLLQSTNYVTKRQSLKLLGEILLDRANFTIMTRYIASADNLKLMMNLLKDKSRNIQFEAFHVFKVFVANPNKNKPVLDILSKNQDRLISFLSTFHNDRNEDEQFNDEKAFLLKQIQDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N470</accession>
    <name>A0A9P6N470_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">DUF726-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_001719</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMCO4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000014">
        <property type="protein sequence ID" value="KAG0024527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N470"/>
    <dbReference type="OrthoDB" id="277931at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007941">
        <property type="entry name" value="DUF726"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17920:SF3">
        <property type="entry name" value="TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17920">
        <property type="entry name" value="TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4 TMCO4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05277">
        <property type="entry name" value="DUF726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="528"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="573"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="21"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="65"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="162"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="307"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="422"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="35"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="66"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="84"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="168"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="187"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="307"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="332"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="369"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="387"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0024527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="965" mass="104179" checksum="7D661105537A6A40" modified="2023-09-13" version="1">MPLLDQPVHGDASTVLVETSTTVVRLSTDEPVPNDSHSTSAQQDTNSTSIEPDIQLESDGDFEFYMNNSPHNQTTSLSKNSELAGEDDDDDDTDTVNRAQSSKDKSSNSNDSLATVAGVALERLTDAIAAKETTNPEYTQETEVYIEINDFNQQHTTFEAQLPREQSEATNQNKTTSLPTTLKDVNNESANVSSTESSVTTPVSQSPRSCDIGTSKDILTEGQAFAYVGLCLVTANTLFQALDGTETSHAKESLENFVSKLINRLYKHLEIDADTQRTIAQLPQMMIQPEDLLESFVADGTQRIVSSQQVDQSDLYTSRPTSPLRSHHSREASTSSQSSVNSLKQQQQSPPAPIATSNDNSQKDVIVHSTSPTASTSNSATPISSVPRESTSSLQSDLSNGTEGSPSVESFDKVDRKHIESTLSRSSTLVNESQAGPRSSISSQKAITVDLRWTLVADLFLISISDSIYDSRARVLLKTVGTHLGLDWNEIVLFEKGIVKQLQSSTDDGLLKPDTKSRNDESRKRRMIMMGLATVGGGLVLGLSAGLFAPLIGAGIGAALAGAHITGATATAASAFLAGSGGIAVITSGAAVTGSGIAMKKMARRTAGIDTFEFLSIHDYKRVNVILTISGWLDIGEEDASLPFSTLDPINGDHFALLWEPDMLMQLGNAIKLLATEVITLTAQEILKHTLLSALLSALAWPMALTRLGYLIDNPWSIALDRAKLAGLVLADSLLMRSYLGFRPVTLVGYSLGARVIFYCLMELGRLDAFGIVENAYLFGAPITASETQWRQARSAVAGEFVNGYLRNDWVLGFLFRATTGGLGTVAGLRPINNVPGLTNMDLTSHVEGHLDYRIKIPLLMKLMGLKITSESFLDKEEAILHQRSLKINPNEVLKAPKPMMPSKAELAKSEALTESEKLQLEIAFRRPAPKAKIPNLDEIKGLTSEEMEALREALMGAAAAQEVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N478</accession>
    <name>A0A9P6N478_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="1">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">CNA1_3</name>
        <name evidence="4" type="ORF">BGZ80_010676</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6 1">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PPP phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="1"/>
    <dbReference type="EMBL" id="JAAAID010000077">
        <property type="protein sequence ID" value="KAG0022988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N478"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033192">
        <property type="term" value="F:calmodulin-dependent protein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097720">
        <property type="term" value="P:calcineurin-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043360">
        <property type="entry name" value="PP2B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45673">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE 2B CATALYTIC SUBUNIT 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="3">
        <location>
            <begin position="145"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="441"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0022988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="495" mass="56370" checksum="34A96C48DEAA24F5" modified="2023-09-13" version="1">MDDGTTASTLERYNKDVMAPAVTVPTNDMFFSKEFPDRPDLVFLKEHFFREGRLTEEQAIYILQKATDILRREPTLLEVDAPITVCGDIHGQYYDLMKLFEVGGNPETTRYLFLGDYVDRGYFSIECVLFLWSLKIWYPDSVFLLRGNHECRHLTDYFTFKTECRHKYSETVYDACTESFCALPLAAVMNKQFLCVHGGLSPELSTLDDLRRINRFREPPTHGIMGDLLWADPLEEFGQEKTSEYFVHNHVRAAVLKYENNVMNIRQFNASPHPYWLPNFMDVFTWSLPFVGEKISDMLLAILNTCSKDELDDDDLVLNITEGAENVGSSSPTHVPEDTSVATSENIAVTPIASNPASPGAESTEVLLRKEVSRSRIRQKILAVGRISRVFSVLRTESESVSELKDLMGTTKLPYGYLALGAEGLRRAIHSFEDAKRCDIENERLPPTKEEKDKEEKDKIMRAIDEAQHTSQSRLEELEAIKLAEGSDVHGIENH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4G5</accession>
    <name>A0A9P6N4G5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Peroxisomal ATPase PEX6</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Peroxin-6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">PEX6</name>
        <name evidence="13" type="ORF">BGZ80_009930</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:13066"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000064">
        <property type="protein sequence ID" value="KAG0023276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5553750at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016558">
        <property type="term" value="P:protein import into peroxisome matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19527">
        <property type="entry name" value="RecA-like_PEX6_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000109">
        <property type="entry name" value="Peroxisomal biogenesis factor 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000039">
        <property type="entry name" value="peroxisome biogenesis factor 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050168">
        <property type="entry name" value="AAA_ATPase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056995">
        <property type="entry name" value="PEX6_4th_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047533">
        <property type="entry name" value="RecA-like_PEX6_r2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077">
        <property type="entry name" value="AAA-FAMILY ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077:SF9">
        <property type="entry name" value="PEROXISOMAL ATPASE PEX6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23315">
        <property type="entry name" value="PEX6_4th"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0962">Peroxisome biogenesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="12">
        <location>
            <begin position="643"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="12">
        <location>
            <begin position="922"/>
            <end position="1063"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="302"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1201"/>
            <end position="1293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1313"/>
            <end position="1339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="302"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="329"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1234"/>
            <end position="1253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1268"/>
            <end position="1283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="1329"/>
            <end position="1339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0023276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1339" mass="146419" checksum="E8FEEDFDFCADE01C" modified="2023-09-13" version="1">MSPTVDIPSNRNNNAYASVQAKLSVRPEESVSRESNATTLYRLNNTIQVTKPVWSQLCGANTPIDVHASVPVAIVISQDNFQMHTAVSHNARPLLNAIVTRAVLLTSSIDGHVPESAESECFITSEFARTYMPSSTFENQVQITIQKTDLVVLDEVILAATTTEAYETISADPSLILNHFLPPGGDPVILRYEQVYNIQGPSGEPLPVKVLMCNSVLQGIMEEETGIIFTDMAGQALDQPTGVDFFGSAIPNRHLNIFEDEADPFGFDGDFIASRFLVKDHHPNSKSKSAFKDLHFSVADLEDDDDEDEEEEEDNNSFSDVVEDSGDEIDGRKIRREVNGHGRRITSLSSQTKPVEEKEVPVKRTSLDFSPWVQKGHYPSHNLSPQPAPEDDPEARIFVDVSQLGKLRVFSGDWVLVSAKEPKATQRFCRIYGLTFPTNDTTKGLPRVYLPAGLHFNLGAPSSLTIDAAHLKQDEPTVARAVTVARVASPPTVDKALQSACLEALKEWFEEYERVVCEGDVIGVEIDEEAAKLIPKQLNPADASDIDVRLPLTPSDLKTTIYFKLTHLEDSSKPNKHTQLVDPSVTKMIQSGLEHSRVPPKLKRFGRSPAIPALDDPSAPEAFSQLYQLVSSGLHPFSSKLGLNCTVLLHGARGIGKKTVVDWVADLAGIHLMEVNCFDIASDTDAKTEVAVRAKFDKAVACGPCVLLLRHIDALARKSVALETGQEPILSTVLKDCFTQLGDAFKTMGHPVTVIATTGDIDKVPTSVLGCFLHEIGFNAPNEAQRLAILKNLTVTTPLGPDVSLNALATQTAALVAKDLVDLTGRAGLVAIDRVEKSIEEWNKGHVSAQSLVHAGVTVTAADFDTALNKARASYSDSIGAPKIPNVTWDDVGGLASVKNDILDTIQLPLEHPELFASGLKKRSGILLYGPPGTGKTLLAKAVATSCSLNFFSVKGPELLNMYIGESEANVRRVFQRARDAKPCVIFFDELDSVAPKRGEKGDSGGVMDRIVSQLLAELDGMNGGEGSGDVFVIGATNRPDLLDPALLRPGRFDKLLYLSVSTKHEEQLRIIQALTRKFRLHPSLDLANVAEKCPFNYTGADFYALCTDAMLKAMSRTADGIENRVVAINNDETSTLPRPITSQYYLDHLAQPDEILVQVTEEDFDQALAELIPSVSAQELEHYRQVQKMFNSDDFAKDMEAAAAAAEEEREKKNKAGKQKQVNRENDDWELTEASRKVEEAQRLLSAERENAEVSPSSPSKSKGKGRSSDYSHVEQHVERQHQLGVVIRDGEKGDIGLEEPIMVSEEDQVVIQETIDHQGNGGSVKETKKRSKGKGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4I1</accession>
    <name>A0A9P6N4I1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CUE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_009736</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000061">
        <property type="protein sequence ID" value="KAG0023333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N4I1"/>
    <dbReference type="OrthoDB" id="5577209at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14364">
        <property type="entry name" value="CUE_ASCC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052586">
        <property type="entry name" value="ASCC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041800">
        <property type="entry name" value="ASCC2_CUE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003892">
        <property type="entry name" value="CUE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21494:SF0">
        <property type="entry name" value="ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21494">
        <property type="entry name" value="ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 2 ASC-1 COMPLEX SUBUNIT P100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02845">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00546">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51140">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CUE" evidence="2">
        <location>
            <begin position="476"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="734"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="734"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="767"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="808"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="822"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="835"/>
            <end position="849"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0023333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="855" mass="95480" checksum="E2B73E1D880F659B" modified="2023-09-13" version="1">MAIVTDLLPFVTPLTDQTLTETDFSIAVDDWNESLSKILRHNTKAFWKELLQNVSLSRFLNLFLGEYASFRGNKDDIWIMELGEVIRRVFMIYHRISVTMTEPDAIAISNELLADQGLSDPGSALLDQGLVSTSVLMDFAGIYGSSDPEGVSRIVGTILQNTPSLIGDFRASTNTVVQIIRRVQKRFEKGVSGGAGKGKGKGKGVSPSMSPEPNAPELDQGKLNEVMQYTSALSNIAYALDAVSAVSPLLATELLQHPTFLQCLTGCYNYTLPILTKVLIDNQAVGGINARPVLSFLRLKMLSIVNNVLDGIYKQHRSNLDTDSQSSTGPSLSEGEDEAAALTDRLCEVIVNLYEQSPLQEHMVPMVDAPMILDLELQFCISERLSDINSKMFNGENDRLNHWVVMLTNLQQFNPATQDFIYEHNMRKSEKMAREMSTIYIGLEQDRSSTTTISDNSAPRVLVAPMSVDQEEDYVKRTMLISQLQDLFPDLGDGFLEACLIAFKDNPEVVTMRLLEEDLPSDLATMDRSTARSMPHRVESAPTSMALVEVPGFKDPQEQDVLSNRRNIFDGDEFDVFSGNIVDKSKVSRGGKKGPKDAAVVLDDKSFVSEHKSAILQAVDSMYDDEYDDTYDSMGVNSAGADFRLVDDIDANTDEGVTKQANGRAQMQIDPSIEHEEALINMYTGQKEVFNRSAEARRSKKRQELRNLTKMSDEQLEGWAIMFGRNPRRAEITQKYEFRGEQTEVERSEPIDKRRGGRMPFVEKNATQSRPNQQQQQPQQQQGSRPQQGQKKSQQSSRTSTPDTSSPKQGQEQQSKTSPAGNDKRDRAKSERQKSAKANHNRRNQHAKKMAVVNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N516</accession>
    <name>A0A9P6N516_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Vacuolar protein sorting-associated protein 41</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">VPS41</name>
        <name evidence="9" type="ORF">BGZ80_008221</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Required for vacuolar assembly and vacuolar traffic.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Vacuole</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the VPS41 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000044">
        <property type="protein sequence ID" value="KAG0023744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N516"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030897">
        <property type="term" value="C:HOPS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009267">
        <property type="term" value="P:cellular response to starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034058">
        <property type="term" value="P:endosomal vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016236">
        <property type="term" value="P:macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000932">
        <property type="entry name" value="Related to Vacuolar assembly protein VPS41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000350">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 41 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057780">
        <property type="entry name" value="Beta-prop_Vps41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000547">
        <property type="entry name" value="Clathrin_H-chain/VPS_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016902">
        <property type="entry name" value="Vps41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045111">
        <property type="entry name" value="Vps41/Vps8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12616">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING VPS41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12616:SF1">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 41 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23411">
        <property type="entry name" value="Beta-prop_Vps41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23556">
        <property type="entry name" value="TPR_Vps41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028921">
        <property type="entry name" value="VPS41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00299">
        <property type="entry name" value="CLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50236">
        <property type="entry name" value="CHCR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0813">Transport</keyword>
    <keyword evidence="4" id="KW-0926">Vacuole</keyword>
    <keyword evidence="5" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Vps41 beta-propeller" evidence="8">
        <location>
            <begin position="138"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="188"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="6">
        <location>
            <begin position="724"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="691"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="15"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="33"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="48"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="700"/>
            <end position="709"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR028921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF23411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0023744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="972" mass="111399" checksum="099300A07F352233" modified="2023-09-13" version="1">MSSTHEPGSIADATKTPSTRGSHEISTNPTHGHLHDVHSGHADHLEGEGEEHEGEVEEEEEEEEGEEEEEEEGEDGEDGEEEEEEVEEEEEEEEEEEEEEEEEEEEEEEEEEEEEGEEEEVEEEEEEEEEEDDEEPKLNYQRLGAGIGDLLKKDSASATTVSERFLAMGTHWGVVHIMDFDGNENQQFQAHQATVNDLSVDLDGEYIASASDDGKVVINGLFINENHVFNYKRPMKAVALEPHYARSTSRQFVSGGMAGQLILNEKGWFGNRDVVLHSGEGPIYAIKWNGTFIAWSNDLGVKIYDTTTEQRITFIDRPGSSPRADLFKCRLCWRSETELLIGWAALVKIAVVKNRPKDQMKAGLPAQYVEITNMFQTDFIVCGIAPFKDMLLLMAYLVDDIDEIGHISGAERNEHKLAKRPELRIINAYNEEISSDALTLHGYAHYQANDYMFEHLPSQDMFYIGSPKDLVVAKERDLDDHIEWLMDRERYAEALGHAREAQIYGGSKKFSASEIGQKYLGWLFERVEFDKAAAQCPSILGSDANLWEHWIYAFAEAKQLKAIAPFIPFSEPRLSHTIYELVLGYFLLHDHQSLFKTVKSFPPGLYKIQTIIVAVEDRLKQDNDNVLLMESLAELYTRDSRPDRALEYFLRLKKPNVFELIIDHNLFPAVLDKAVLLMEFDQHLYNLSKKERDEARTLEENSNGSNTEEPQAPEPKAEDELTRYPAVQLMVQHTEDIPIKRVVSQLKSKPRLLHIYLDALFLRDPHLGFEFHDLQVELYAVYSPSKLVDFLRASNYYSLEKAYRTCEKLDLVPEMVFLLGRMGNNKKALMLIIERLGDVERAINFAKEQNDDDLWEDLLKYSMDKPHFIRGLLQNVGTEIDPIRLIKRIPNGLEIPDLRPALLKILQDFNLQMSLREGCRRILVSDSVAMADQLQRSQKRGISCSGMIHKDGMHSMHKYPPSNFGTDAYMKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SSE0</accession>
    <name>A0A9P6SSE0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007497</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003859">
        <property type="protein sequence ID" value="KAF9995465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SSE0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13405">
        <property type="entry name" value="EF-hand_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="1">
        <location>
            <begin position="4"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="1">
        <location>
            <begin position="75"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9995465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="111" mass="12771" checksum="78615369666FDD41" modified="2023-09-13" version="1" fragment="single">MSDIRADEIKQAFALFDPQNTGRIEPRVFRDFLNASYQTLGDEELKATIRIPTHALDIKEFTTLMNRYNEDQHKDPEEPYRRAFQSINRDGSGHVSTQELKAALDSFLGPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SSP0</accession>
    <name>A0A9P6SSP0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_007020</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003521">
        <property type="protein sequence ID" value="KAF9997389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SSP0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040128241" evidence="2">
        <location>
            <begin position="21"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="46"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9997389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="193" mass="20387" checksum="AAF2E7821897B139" modified="2023-09-13" version="1" fragment="single">MKLKLILLVAACLALPSANASVSIPDINTLRGPSTSTPLPAEGDGSPTDPATTAYTTGTSSRLSLYVPSTIYEDYPGWLPLYKALVFQGIPVKVTKSITEAITHPTVLAYQALQSKYMGSTDGATWKNYVNAGHTLIAIGLTSTDSNLKSVFGVTPNTTTNKNKRKVIALNAPLAAFPASKVNAQFDQSVVND</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SSQ3</accession>
    <name>A0A9P6SSQ3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_006990</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003500">
        <property type="protein sequence ID" value="KAF9997529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SSQ3"/>
    <dbReference type="OrthoDB" id="2410986at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9997529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="324" mass="36216" checksum="9F9217689B78AE64" modified="2023-09-13" version="1" fragment="single">DLILWRVAIAVDEGAEDEIILAANITSKEPLETTTTLTKAFKDVPTEDTIHIIVERLQAPITQNFESEARIAKLEEIEDLRGNREDGDAVLTIVHSRETPQHETGGIERLSNDAQFRKIIQQYRKTNTKTIAVALETPTKKYTNFTLTGVNNLYGISNLKVPEISDLPPFEGISSGTLDSDLHKESLKRLIDELDSRIRSIPAYTLNDAPCSAYVCSFFTQVVLIFNDELTIAPERLLRGRHGHGKVDYSIESLANDGTRHILCVTEVKQEDFRRGVAQNLVQLESSLAARKRKRCDEDGGDRELEDDKSVPLKAYGIVTDAAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SU71</accession>
    <name>A0A9P6SU71_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_005729</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002816">
        <property type="protein sequence ID" value="KAG0003832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SU71"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050562">
        <property type="entry name" value="FAD_mOase_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356:SF2">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356">
        <property type="entry name" value="FAD-DEPENDENT MONOOXYGENASE ASQG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="1"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0003832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="423" mass="47889" checksum="178DC3C9273BDCC5" modified="2023-09-13" version="1">MLGAVLESANISYHILERAQEPRPLGSAIAISANILPVFEQLGIYEELKSISLPHISLDMYNTNLDNFCSLDGECHRAVTGYEHQIVARPRLYDLLHRKVPEYKISRGKKVIRTKERDDGVTVHCSDGTEYECSILVGADGAYSVVRQNMYKKLDEEGNLPPSDKEDFTIAYINMVGISSPPNPEKYPQLSDTDRTHFRIVIGDSNESCLFVTAPDNQICWGIQIQLSADEATQHQFKNSEWGPESIDTMMKDFEEFPCAFGGTMKEIFDATPKHLISKVFLEEKLFQTWYHGRSVLLGDGAVTAMKDAVVLANCLYNMNDTSEKSIETAFANYYRQRYSDAEYMAKSSAIITNVMYGHRWTDRLLRKVISSYLPNWVKTKGGVVRYSNRPQINWLPLVENPDQGYVLPQEGRELVEKGALAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SUK9</accession>
    <name>A0A9P6SUK9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">MTHFR SAM-binding regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_005498</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the methylenetetrahydrofolate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002705">
        <property type="protein sequence ID" value="KAG0005180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SUK9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004489">
        <property type="term" value="F:methylenetetrahydrofolate reductase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029041">
        <property type="entry name" value="FAD-linked_oxidoreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003171">
        <property type="entry name" value="Mehydrof_redctse-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053806">
        <property type="entry name" value="MTHFR_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45754">
        <property type="entry name" value="METHYLENETETRAHYDROFOLATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45754:SF1">
        <property type="entry name" value="METHYLENETETRAHYDROFOLATE REDUCTASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02219">
        <property type="entry name" value="MTHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21895">
        <property type="entry name" value="MTHFR_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51730">
        <property type="entry name" value="FAD-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MTHFR SAM-binding regulatory" evidence="9">
        <location>
            <begin position="124"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="MTHFR SAM-binding regulatory" evidence="9">
        <location>
            <begin position="361"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="92"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF21895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0005180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="443" mass="48530" checksum="6D298442DE03D048" modified="2023-09-13" version="1">MPIQSYNGFRRITNLAKIRIPATVTHALEPIKTDDQKVKDYGVELAASIIDSLLKAGISGFHICTLNLEKSVRLILERVGFIPSAASATAGKQQKSQLGNDPTHPNLSGAPAAAAATAAIAADTHLNPLIWKAPDSTHGHSESWDDFPNGRWGDARSPAFGDLDGYGASLKVEPAKALEMWKRPKNTEDISQLFVQFIQGKIPLLPWSEGSPLPETEAIQSKLVACNERGLWTVGSQPAVNGKPSTDPLVGWGPKGGYVYQKGFLELFVGPNEVEAMIQKLRTVSPWITFLAASRDGDIVTNTTGDVLEEQRKIAELKKVCGKKQSDLDSSAGVSSSTRNTPPPVCATPFVSKAGDELVEGPNALTWGVFPGKEIIQPTVIEKVSFLAWRDEAFEIWREWEHLYPKGSESRKLLHQIGHDYWLLNVVHNDYRNENGIWDIILS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SVS4</accession>
    <name>A0A9P6SVS4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Histone-lysine N-methyltransferase SET5</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">SET domain-containing protein 5</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">SET5</name>
        <name evidence="13" type="ORF">BGZ80_004946</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-lysyl-[histone] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl-[histone] + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10024"/>
            <dbReference type="Rhea" id="RHEA-COMP:9845"/>
            <dbReference type="Rhea" id="RHEA-COMP:9846"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61929"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:10025"/>
        </physiologicalReaction>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002471">
        <property type="protein sequence ID" value="KAG0007208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SVS4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042799">
        <property type="term" value="F:histone H4K20 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045814">
        <property type="term" value="P:negative regulation of gene expression, epigenetic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46402:SF2">
        <property type="entry name" value="HISTONE-LYSINE N-TRIMETHYLTRANSFERASE SMYD5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46402">
        <property type="entry name" value="SET AND MYND DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SET" evidence="11">
        <location>
            <begin position="71"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="MYND-type" evidence="12">
        <location>
            <begin position="123"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00042380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0007208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="396" mass="44537" checksum="AB8D4D8E1AEA20E0" modified="2023-09-13" version="1" fragment="single">IKEKDPNLGIKKVLAEIQAREPTWLVSEKRVKKMMGEAGISVARPELEGEIDPSIPVSHIDKEVDVSALTNGLVKARMINKVIGKGLFAAQDLPKGKVIFTEFPFIYFPPMKRYNMVVKGDACGLCARTIKHGNLLICGCPTCGKIKYCTKACRQTAWDSSHRFECGALNPALKEYINYCVEENWNAGMGALRCYERILIANETSPQELASVLKHLDAFATVSQEERQKKETSWDMMGDQSRTIWEKAHKLLIKGCTYPLKETGKAPVLTKPLPDHLKDSLFSMDTYLKFVGRYNINNQDGGLYLLHSSLNHACVPNAIIDHPGAGTNYGVSVRLARDIKRDEQLQITYCDPRWKRETRQQYLLTEYLFTCKCKRCTGSDDSLNEEISQALGLAPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWJ4</accession>
    <name>A0A9P6SWJ4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ca(2+)-dependent cysteine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">MCA1_1</name>
        <name evidence="4" type="ORF">BGZ80_003627</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C14B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001974">
        <property type="protein sequence ID" value="KAG0008276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWJ4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004197">
        <property type="term" value="F:cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12660">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050452">
        <property type="entry name" value="Metacaspase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011600">
        <property type="entry name" value="Pept_C14_caspase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48104:SF30">
        <property type="entry name" value="METACASPASE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48104">
        <property type="entry name" value="METACASPASE-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00656">
        <property type="entry name" value="Peptidase_C14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040383189" evidence="2">
        <location>
            <begin position="21"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase C14 caspase" evidence="3">
        <location>
            <begin position="67"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0008276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="345" mass="38090" checksum="65CF59F53C3508D8" modified="2023-09-13" version="1">MFGFAFFAFVFFYFLHHIQQDPTQQDIKYSYHISPTAVPSPPEGWAMRQSRNQRPPSDFKLSNCQGRKKALFVGINYFGQQSELRGCINDVKNIKSFIMQNFGFTEENSLTLTDDQQDPTRIPTHANILAAMEWLVRDAQPNDSGHGGQIADEDGDEDDGYDETIYPVDHQTAGVIVDDTMHKILVHPLPAGCRLTAIMDCCHSGSALDLPYIYSTTGTVKDGNILADVGVGVLNAGLAYMRGDMSAVFSGLSGMGMKILAQKTRDRSTKASPADCIMFSGCKDTQTSADAQEQGFGMTGAMTYAFITAYLQLLNSIRDILRSKYQQKPQLSASHPVDLSLLFTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWS3</accession>
    <name>A0A9P6SWS3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_002975</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001761">
        <property type="protein sequence ID" value="KAG0008869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWS3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13527">
        <property type="entry name" value="Acetyltransf_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0008869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="473" mass="53719" checksum="E3D087B94298E848" modified="2023-09-13" version="1">MVHRAFRSDCRITTVYDFALVENTRAPEGDNPIIAGVSLQQDIGYFGKVKLMYGISEIIATHSDYRNKGLMRRLFHDLVHPASDLRGGVVQIIAGIPHFYRQFGYEYALDFGSYNPQKLNDLTSILPLAEHESVEKGGHGEPFLLRTPSVDDLPYLVEMSTPEKRLSQAGAGFLYDENYWRFWIRDAVANMTSKFDVSRSHWIIVDAKAGKDCGVAMARGCPMLSIEMFVLDEEHNYRDAMHSVLRQILTIANGPTAWEQKQQLEEAKRAREVKEQQGATTTNQKKIQGMTLSLDPEHPIMKLFASKSTVTTTKSKIYTRIPSYANFLLKIAPVLEDRLAQSCLKEITVIWQFNFFRKVVGSAGKGVEVVFESGKLISARDDWVEPSPKEKVMAARERIAKAKEENRPDFKPLVYQAQFAPLTFTRLVVGDMTMDQMTDIYAECGIREGGDDAKLMLDILFPKQIFHFDLHSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWZ1</accession>
    <name>A0A9P6SWZ1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FCP1 homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_003396</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001897">
        <property type="protein sequence ID" value="KAG0008469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWZ1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090364">
        <property type="term" value="P:regulation of proteasome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011943">
        <property type="entry name" value="HAD-SF_hydro_IIID"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051658">
        <property type="entry name" value="UBLCP1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02245">
        <property type="entry name" value="HAD_IIID1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48493">
        <property type="entry name" value="UBIQUITIN-LIKE DOMAIN-CONTAINING CTD PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48493:SF1">
        <property type="entry name" value="UBIQUITIN-LIKE DOMAIN-CONTAINING CTD PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FCP1 homology" evidence="5">
        <location>
            <begin position="186"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0008469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="371" mass="41578" checksum="6DDC3AB970101B11" modified="2023-09-13" version="1">MISNSTTDTNPTLAPDTNGGQTTLLTQKTVVLEGDLVQSTPTDQDPELPIPATTLSPAPALSTTFSADASVIETIAPATSSSLHIDHLNENNKRLISLTAQWNGKKLPFEVDLDYTIGELKNKLTFLMMGTPEAKVIKAPETLPDVLNDLEEDYTPDDEAFASMAQNQKNLKATIAKCKIDIMNPLRSGKKLLVLDLDYTLIDCKALNNPLIDVMRPGLHDFLAVCYEHYDIVIWSQTSWRALEAKVTTIGLLTHPDYKISFVMDISTMFSVMSQRDGKPFKHQVKALDIIWSKFPQYNARNTIHIDDLSRNFAMNPRSGLKIGAFKNGAISRHTDRELYHLARYLVEISKANDFKELDHKSWKNHRRANP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXD3</accession>
    <name>A0A9P6SXD3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 11">Chitin synthase</fullName>
            <ecNumber evidence="2 11">2.4.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">CHS1_1</name>
        <name evidence="14" type="ORF">BGZ80_002016</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10 11">Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>[(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n) + UDP-N-acetyl-alpha-D-glucosamine = [(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n+1) + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16637"/>
            <dbReference type="Rhea" id="RHEA-COMP:9593"/>
            <dbReference type="Rhea" id="RHEA-COMP:9595"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17029"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="EC" id="2.4.1.16"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Cell membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the chitin synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.16" evidence="2 11"/>
    <dbReference type="EMBL" id="JAAAID010001485">
        <property type="protein sequence ID" value="KAG0009826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXD3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030428">
        <property type="term" value="C:cell septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004100">
        <property type="term" value="F:chitin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006031">
        <property type="term" value="P:chitin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04190">
        <property type="entry name" value="Chitin_synth_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004835">
        <property type="entry name" value="Chitin_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013616">
        <property type="entry name" value="Chitin_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914:SF9">
        <property type="entry name" value="CHITIN SYNTHASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01644">
        <property type="entry name" value="Chitin_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08407">
        <property type="entry name" value="Chitin_synth_1N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="4 11" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="554"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="600"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="634"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="690"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="823"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="851"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin synthase N-terminal" evidence="13">
        <location>
            <begin position="139"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="100"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU366040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0009826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="885" mass="99864" checksum="BF88FC64F90FA565" modified="2023-09-13" version="1">MSRYPPMGNPTMQYNPAENLFDEDPPRRQEGLLLSSGYNANAPRNSSNLGFAPTPVMPPTFIPQSPYPPFRSSMPMPSPRFSNSPNMNQFHPHVDMPSNPIRGPGGFVPPNSQGLNPPGTPDRRHFGPAPTAQRRRFHTTKKVKLTSGNLVLNCPVPQKFLSTLKYKDDEEFTHMRYTAATCDPDDFASENYTLRPLIIDGTPRETELFIVMTMYNEDEVLFTRTMHGVMKNIRHLTTRDRSRVWGPDSWKKVVVCIVSDGRTKVNPRTLNVLAAMGVYQDGIAKNIVNDKPVTAHIYEYTTQVTVDPDMGRSGAEKGYVPVQILFCLKEKNAKKLNSHRWFFNAFGQILKPNVCVLLDVGTRPGSKSIYHLWKAFDLNSNVGGACGEICAMLGRGGSQLLSPLVASQNFEYKMSNILDKPLESVFGYISVLPGAFSAYRYRALQNDSSGQGPLEKYFLGEKFHGSDANIFTANMYLAEDRILCFELVAKRNSAWVLQYVKSAYGETDVPGTVAEFISQRRRWLNGSFFASVYALTHSMAIWRSDHSTARKFFYSFISLVFSWFALANFYLTFYIIGNGLIYMINDDGSIQHSPFGDNDIGYWVFTVTRYVYILLIIIQFIVSMGNRPQGSNWAYKTSMGFFGLLMGYMLFGAIYMTISGIERVQDQIAVMQNQTDVSMSTASLYFENPMFTNTVISLVSTYGLYFFASFLFLEPWHMFHSFLQYLFMLPSYVNILNVYAFCNIHDISWGTKGDTSVATDLGVAKKTAEGGVEVSVPTDTHDINNAYDEAVASLSVKTVELKKHRDAKTKQEDYYREIRTRVLLAWILSNALLVALITSTIFGSFKKTSTIYLGIILWSVAGLALFRFFGSVTYMILRLFNGRIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXQ4</accession>
    <name>A0A9P6SXQ4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_001465</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001335">
        <property type="protein sequence ID" value="KAG0010453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXQ4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0010453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="69" mass="7638" checksum="B8E236C9DEF4DCD0" modified="2023-09-13" version="1">MRSDDLEAIFKRDKVEPAQVIQPAELFKMTKTQPALYYKPVKEPPSIATDATLSTDVVMSPTPAATETK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXS2</accession>
    <name>A0A9P6SXS2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Tbc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_002235</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001547">
        <property type="protein sequence ID" value="KAG0009592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXS2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00180">
        <property type="entry name" value="PKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.270:FF:000044">
        <property type="entry name" value="TBC Kinase homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957:SF168">
        <property type="entry name" value="TBC DOMAIN-CONTAINING PROTEIN KINASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="Rab-GAP TBC" evidence="3">
        <location>
            <begin position="598"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="515"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="854"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="533"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="866"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="885"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0009592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="898" mass="100812" checksum="0BE26ED5EBD807D3" modified="2023-09-13" version="1" fragment="single">MATFAVCSDLHRHPSTRNAGLAAISFCANDNIDDELHGVAPATSCIFGQSQFLKSLSHPNLCEYLDVIKGKRDRVFVVQEHYTNSLEAIRSAQESDENESTAPKGQDLVQIRSWAAQILDGLAYLNTHGIVHRALALSNILLNEDGIVKLSNYGLYNMTKGGTLVQFSIGDPHYLSPVTLGQSHAIGLKDYSVDLWSVGVILTELYLGESFWRKDRLDLDEIIASLFAIRKLSIRDKNWIKDCPESVGINAVVLKFLQTGSKDATQGRNKSEAKDLNDEEQDFVAFLRDCFRLGPPTCQEPAQLRNHIFFKPYDSLQEGNKNMAGPRLALWHQKPYIQSSFLPDYEGEVERLRKAISSGKSISDPESTSENPVKHEILSKLPLSQVFYLWKLAGGDVEAQFRRKGRLVGTPAIQLLPKVVQVAETKEEQRNNSNVNTRGPVKDIADLFSDVPCILPLENLEAEILKSIHEPNKDQFSWDTDYFLLSDPDEMNFLQSTMGSDDKVDKDGEENVFLYPDSMRSPSKPKTAQASGLGTGGGGSPGGATSLGQQPVKTRVKVPLAIREKDLGYQYQRLSMFTDLLLQYPASRAEILHHSKIDIPPLVRGKVWAAILGVVGDYQDIYDGFDKYTEKMTDRQIELDVPRCHQYNQLMFSPAGHEKMKRLLKCWVEANENLVYWQGLDSCCAPFLTLNFNDEALAFACIQLFLPKFLKDMFLHDNSQVIHEYLAVFKHLLSYHDPDLSSHLDQIRFIPQLYAISWFMTLFTHIFPLDKIYHLWDKILVGPSSLSLFVGIAILQQFRQELLRSEFNEAIGIFSDSFPEMDIEKCIETALSMCRVTPPSTCWLSYDQESREMKKQLSTGARPNENDNTNNNNGALGANGEAVSGATTEQTNQGRGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SY25</accession>
    <name>A0A9P6SY25_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Clathrin light chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_001855</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Cytoplasmic vesicle membrane</location>
            <topology evidence="1 6">Peripheral membrane protein</topology>
            <orientation evidence="1 6">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Membrane</location>
            <location evidence="6">Coated pit</location>
            <topology evidence="6">Peripheral membrane protein</topology>
            <orientation evidence="6">Cytoplasmic side</orientation>
        </subcellularLocation>
        <text evidence="6">Cytoplasmic face of coated pits and vesicles.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the clathrin light chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001434">
        <property type="protein sequence ID" value="KAG0010025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SY25"/>
    <dbReference type="OrthoDB" id="5512at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030132">
        <property type="term" value="C:clathrin coat of coated pit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030130">
        <property type="term" value="C:clathrin coat of trans-Golgi network vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032050">
        <property type="term" value="F:clathrin heavy chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072583">
        <property type="term" value="P:clathrin-dependent endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000996">
        <property type="entry name" value="Clathrin_L-chain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10639">
        <property type="entry name" value="CLATHRIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10639:SF7">
        <property type="entry name" value="CLATHRIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01086">
        <property type="entry name" value="Clathrin_lg_ch"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0168">Coated pit</keyword>
    <keyword evidence="5 6" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="3 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0010025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="275" mass="29809" checksum="99203449C7BA16D4" modified="2023-09-13" version="1">MDDFSFDAPSSKKTDFGSDDPTADFLAREQAILGSDADFLATLSSGTDVTSPTKISDDFESNFPSFAEHEASLTSPPVSGRANEIPTPTIAVAADDDEFGAFNTEYPAIETTDSVSPSQVFAASIPIQATGASGGFGSPSPSMSLNRSPQFTAPEVPAIVKEWREKQAVIVAEKDERSEVKRQETIGAAHEAIDRFYEDYNQKKAKLLAENRDKEAEFLAKRDDVSSGTQWERINRHLDSSPAAVAAALKAGRRDTSRMRDLLRDLEKDPNAPGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SY86</accession>
    <name>A0A9P6SY86_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_001045</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001230">
        <property type="protein sequence ID" value="KAG0010979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SY86"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015079">
        <property type="term" value="F:potassium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031606">
        <property type="entry name" value="Kch1/2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16944">
        <property type="entry name" value="KCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="62"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="101"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="205"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="318"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="338"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="354"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="383"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="395"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="409"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="419"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0010979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="431" mass="48459" checksum="7AF9141187A187FD" modified="2023-09-13" version="1" fragment="single">MEPPLPQPPSSETSQVYNSNAVPHRVGSLLLQATAVTVPTFSAELDLGSIANPQKHSPIKRYLFASLLFKPFIALLLDCFSLAYLSSWIRDSLGKSNSTGFVFYIIATCGAMLIVCYGGWRATQVLKKGHIQAIFVNREAYRWTCLTSYEKFLFFERIGQGYGNMDALVFFTWFTLRAAVAHQQSQIDRGEAPTLNLPKMSGITHVALALNIMLQVCNLIQFLGAIVVLLLVRSGKLISLRKDEHLHTYCQRNLNVRIVRMYKLAKSPGTRAPLRENDQLGQQMSQYAHAIDSEGGIDISQLASLAWDDTETQDDTIDYNHYAYRPRPISTGPPARKKSGDDSERIEMTEKPQEQQQQQQQEWISSSASSLPVPPPAPGSFSYAQWQHLQIQKQKYGDDRSKYEPMHWNPNNMGSSENQGQVQPQTQSQGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYC4</accession>
    <name>A0A9P6SYC4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">AMP-dependent synthetase/ligase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_000624</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001131">
        <property type="protein sequence ID" value="KAG0011522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYC4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009898">
        <property type="term" value="C:cytoplasmic side of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005324">
        <property type="term" value="F:long-chain fatty acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004467">
        <property type="term" value="F:long-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044539">
        <property type="term" value="P:long-chain fatty acid import into cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43107:SF15">
        <property type="entry name" value="FATTY ACID TRANSPORT PROTEIN 3, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43107">
        <property type="entry name" value="LONG-CHAIN FATTY ACID TRANSPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040434777" description="AMP-dependent synthetase/ligase domain-containing protein" evidence="5">
        <location>
            <begin position="24"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="6">
        <location>
            <begin position="2"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0011522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="567" mass="63278" checksum="B4250C8866F8A43E" modified="2023-09-13" version="1">MYMTNSPLYVISWLALLKIKAVAVFINNQIAGPVLLNSLTTANSRMLIFDYELVGPLEESLDGIRDLGYAMYSITPEEHAHVGFKEQNKDPSARFFDFMTWRQFGAEGFTRESRRDVDIGDAAALIYTSGTTGFPKAAVMDHGRCTMAPSAWAGICKITDKDRLYECLPLYHSAGAIIGIGQGWMSGSTVVLARKFSTTSFWKDVREKDVTLIQYIGELCRYLLNAPENPLDKANNVRLIFGNGMRPDVWSKFKERFGIETVFEFYTMSEATTALLNLNGGEDGVGAVGFRGPIVRAFQANVHLVKVDPDTEELIKDKNGYCIECAPGEVGELITLADNKTNQSRFVGYYNQPKMSSAKLIQNAFVQGDQYMRTGDLLYRTKDHFWYFADRAGDTFRWKGENVSTAEVADTLGHVDGIASCTVYGVTIPSQDGRAGMAAIVLKDNYWDKDNGAGIKSIESDGPQAGMELAPVSGPKINEKLLDDFITRLGSHASKRLPSYAIPRFIRICEKELDITGTFKNKKVELKKEGYDLSKVQERIYWWAPQGRYLPFGPKENSLIHSGRARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYU2</accession>
    <name>A0A9P6SYU2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cytochrome c oxidase subunit 5A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">COX5A</name>
        <name evidence="11" type="ORF">BGZ80_011671</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Energy metabolism; oxidative phosphorylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cytochrome c oxidase IV family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000969">
        <property type="protein sequence ID" value="KAG0012540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYU2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045277">
        <property type="term" value="C:respiratory chain complex IV"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006123">
        <property type="term" value="P:mitochondrial electron transport, cytochrome c to oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00922">
        <property type="entry name" value="Cyt_c_Oxidase_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.442.10:FF:000002">
        <property type="entry name" value="Cytochrome c oxidase subunit V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.442.10">
        <property type="entry name" value="Cytochrome c oxidase subunit IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004203">
        <property type="entry name" value="Cyt_c_oxidase_su4_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036639">
        <property type="entry name" value="Cyt_c_oxidase_su4_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10707:SF10">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10707">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02936">
        <property type="entry name" value="COX4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81406">
        <property type="entry name" value="Mitochondrial cytochrome c oxidase subunit IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0012540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="160" mass="17403" checksum="841609B4C191547A" modified="2023-09-13" version="1">MLRNLARPAIRATQRRCASTASASEIPLANLELRWKTLSANEQSSLTKQLEQAQAGDWTKLTLEQKKAAYWVAFGPHGARTPLHGPNHGLKVFAGTTGVVAVGCALFFWIRSKGGEKPTTTTKQWQEAQNEYARANKINPISGISSEGYKGTGYVASSKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZ07</accession>
    <name>A0A9P6SZ07_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Rna-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_011787</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000993">
        <property type="protein sequence ID" value="KAG0012373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZ07"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010608">
        <property type="term" value="P:post-transcriptional regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07920">
        <property type="entry name" value="Pumilio"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000237">
        <property type="entry name" value="Pumilio homolog 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033133">
        <property type="entry name" value="PUM-HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033712">
        <property type="entry name" value="Pumilio_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001313">
        <property type="entry name" value="Pumilio_RNA-bd_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12537:SF13">
        <property type="entry name" value="PUMILIO HOMOLOGY DOMAIN FAMILY MEMBER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12537">
        <property type="entry name" value="RNA BINDING PROTEIN PUMILIO-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00806">
        <property type="entry name" value="PUF"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00025">
        <property type="entry name" value="Pumilio"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50302">
        <property type="entry name" value="PUM"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50303">
        <property type="entry name" value="PUM_HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="5">
        <location>
            <begin position="379"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="domain" description="PUM-HD" evidence="6">
        <location>
            <begin position="496"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="2">
        <location>
            <begin position="526"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="2">
        <location>
            <begin position="562"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="2">
        <location>
            <begin position="598"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="2">
        <location>
            <begin position="635"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="2">
        <location>
            <begin position="671"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="2">
        <location>
            <begin position="707"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="2">
        <location>
            <begin position="743"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="2">
        <location>
            <begin position="779"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="3">
        <location>
            <begin position="379"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="152"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="473"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="21"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="48"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="476"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0012373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="993" mass="108919" checksum="2C5205C36941355D" modified="2023-09-13" version="1" fragment="single">MAMKSQIRTSEGLTGDEIVQQRLSRTASSSGNVEESNAPLPNETDQEREDREVAEKLEQKRLEHERQRIQKRELFEKQMQQLEIQQRQEEQAMLAAKNNGASGMNRGKIGSFSVSSETSSQVVASLRSLPASRRNSNDAVDLWGEMEKLSIGDRTKTSMDGLPKIGGRSGSGRDEGSSPSEPTYDDNTHLSKFTERFIFEDDNDSPTSRLPSLNMNRVLHDDGIWKDKQGLGVGSTGLGSSTSYLHRYLQMGNDDDSFPTMLSTSSSALDLAKIPHSTGLHHSGGLDSGLTSEWPQYSKPLSERIPTGSHMPQRTNSLVGYGLTNNPEESLKSALPKLTSPYSSSEIPTRFSKGSTLPAFDELNDQNLLLKSDIGPADVCLQFQQGYCPRGDMCPYVHSHALPTTSRSSAGMPLSPGLGMTAGTMAGSSSFYTRVSGSNGAGSTHSLVGGPGFPFTVTPNVFNNTSASSNNLLRMQQQQQQQQQQQQQQQQQQQSSNSIALANKANQKRPTTDVEANRFVGAALEGFVGQIYSLCKDQHGCRYLQKKLEEQNDKYLAIIFGEVFGHFVELMTDPFGNYLCQKLLEFCGDEQRTIIVENVAPELVNISLNMHGTRAVQKMIEFLSTPQQIAIVVVALNPSVVTLIKDLNGNHVIQKCLNRFASDDNQFIYNAISAHCVEVATHRHGCCVLQRCIDHASVSQKIQLVREITYNALTLVQDPYGNYVVQYVLDLADNRFTDALIRRFIGSICVLSVQKFSSNVMEKCIRVAEPETRKFLIEEMINKSRLDKLLRDSYANYVVQTSLDFADPIQRAQLVECIRPLLPAIRNTPYGKRIQGKLHRDQMSNLSSPMNHLAINGAMGMNGNMGSINNNMAVMNGMNGMNGAMPMGGMNGMNGMPNHGHGHGHNPAMNNMGMNGGMNGGMNGAMSGGMPMPNMGTMNGNMGVGMNNVNNMSGMNVNGNMNGNMMGYGFPGMNNHFGNVGMIGMNEYNPYGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZC8</accession>
    <name>A0A9P6SZC8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_011129</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000858">
        <property type="protein sequence ID" value="KAG0013348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZC8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="154"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="207"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0013348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="244" mass="27467" checksum="2F70450C9B1142DC" modified="2023-09-13" version="1" fragment="single">MTKQKKTPQWYPGTLNLPNAQYFLSAKDPRDFDYVAYLTFIKPSSRQLRDVTSEWLKTVIPTLKNSPCQELREAGNRLTTEWTSKKASRDAFWENLAKAEEREQEKLDRMKRLKSAGEQRLRAAEDYLVEETKQDFELETKLYKAASSSTQVLPVSQHESSASSSSSSSLNVPSVTPSDSTSSLTDILDSTLTTNAMSNSIPNMVESRSASNNAATSSRKRKMSKSSVISEDCWHDLYVSLSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZI2</accession>
    <name>A0A9P6SZI2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Acid phosphatase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_010773</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000789">
        <property type="protein sequence ID" value="KAG0013898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZI2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009395">
        <property type="term" value="P:phospholipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007312">
        <property type="entry name" value="Phosphoesterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31956:SF8">
        <property type="entry name" value="ACID PHOSPHATASE PHOA (AFU_ORTHOLOGUE AFUA_1G03570)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31956">
        <property type="entry name" value="NON-SPECIFIC PHOSPHOLIPASE C4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04185">
        <property type="entry name" value="Phosphoesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040384538" description="Acid phosphatase" evidence="2">
        <location>
            <begin position="26"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0013898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="303" mass="32993" checksum="90C8CEB463B538F7" modified="2023-09-13" version="1">MLFKKFASLTLLAATAFAQAPKGAAFDHIVIIFLENTDYALASTDSYFQALIPQGILLDNYHGLAHPSQPNYIASIGGSTHSVTSDSTYNLSPSYSTIVDLLEAKQLTWKTYQENIPSVCYTGSSSSSLYYRKHNPFVSYGSIYKNSTRCKNVVSATQFTTDVNNGALPNYSFYTPNIKNDGHDTTVAYAGQWLTGFLTPLLSNSNFMKNTLVVVTFDEAEDYSDTTNHVLALLLGDAVNGTANTVDSTYYTHYSLISTVENNWGLGNLNLGDVGQLGNVFNLVASKTGYQNVAVTNPPPLNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZL0</accession>
    <name>A0A9P6SZL0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_011463</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ADIPOR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000924">
        <property type="protein sequence ID" value="KAG0012858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZL0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038023">
        <property type="term" value="F:signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006882">
        <property type="term" value="P:intracellular zinc ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004254">
        <property type="entry name" value="AdipoR/HlyIII-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20855:SF52">
        <property type="entry name" value="ADIPONECTIN RECEPTOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20855">
        <property type="entry name" value="ADIPOR/PROGESTIN RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03006">
        <property type="entry name" value="HlyIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="49"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="81"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="112"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="154"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="6"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR604254-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0012858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="195" mass="22127" checksum="F4446CE895A2DFA2" modified="2023-09-13" version="1">MSASFHCFHCHSEPVSKQWNRCDYVGIVFLITGSFYPAIYYGFYCFQTFQIVYIAMITIIGAAVVVVVVRPEFRGHEYRWIRSCMFLAMGLSAVFPVLHAVVLYGIPLAQKAIAFNYMVCMGASYVIGTLLYGSRTPEHLFPGKFDYFGSSHQIFHVCVLAGVLFHFLGITKAMAFWHDTNHSCAIPISEMRLVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T096</accession>
    <name>A0A9P6T096_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Triose-phosphate Transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">CAS42_3</name>
        <name evidence="8" type="ORF">BGZ80_010556</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000747">
        <property type="protein sequence ID" value="KAG0014249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T096"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004853">
        <property type="entry name" value="Sugar_P_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03151">
        <property type="entry name" value="TPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="205"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="237"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="303"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="331"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="354"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="396"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="427"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="463"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="491"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="domain" description="Sugar phosphate transporter" evidence="7">
        <location>
            <begin position="210"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="549"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="26"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="68"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="96"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="117"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="153"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="551"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="577"/>
            <end position="589"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0014249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="623" mass="69318" checksum="7A1CE683F7A24E4A" modified="2023-09-13" version="1">MTDSFGGPSRAVQLEDGSEEHGAPSLNVSDIQNSRQGHYRTESISSTESHSSDDGIEWENPGYSSEYASDDDNDGYRSDEEDEYEESDREYEQQDTQRLLSSSNTRIGGLGMGMRVGETGTGTTIGLEFEQDTRQNGEDYDALPLTSVDQRSRRYPNRRERIPKRSGRKDDRRSAQTFMPSMIRLGDLQTEQEKLIAKRQLRIKMFWNVFYVFAWYGCSTSLSFYNKWLFSPRHYNFRFPLFTTCLHMIAQFVLSSLTLTLIPSLRPSSAPTPKDFGTKIMPCAVASGLDVGLSNNSLKSITLAFYTMCKSSSLAFVLLFAFAFKLERPTWTLAGIIGVICIGLFMMVMSEVDFALVGFIQVMLASVLGGLRWSLTQLLLERTDTKSGSLANPISTIFFLSPIMGICLCIVAGLFEGYGNIFSSEFFQSAGSSLGTLGLLFLGGVFAFAMVLAEFNLIARTSVVSLSVLGIIKEVVTIVISSLVFHDQLTIINILGLFITLSGIGFYHFMKLRELKAKARKTAKEIVELHLASSTNRVDGSVDRMRAYETRRKRRSHKSRPGYQGIREGTLDNNLSAERRESTIDELPRHATIRSDGSDPPNKDDPLMLGLDSASPIAPPIGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0B2</accession>
    <name>A0A9P6T0B2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_010021</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000655">
        <property type="protein sequence ID" value="KAG0015146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0B2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008521">
        <property type="entry name" value="Mg_trans_NIPA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570:SF86">
        <property type="entry name" value="ADR321CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05653">
        <property type="entry name" value="Mg_trans_NIPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="111"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="167"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="286"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="328"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="371"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="435"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="442"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0015146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="487" mass="53239" checksum="A05053504DFEB029" modified="2023-09-13" version="1">MSFENLSEVLWSTPGSGSILALLNYLSPNETIANSMHNYNTATALFGDNPTNGDGGSDNGPTPHNFVLGITIAVATSFIQSLGLTIQRKSHVLNEAIHPKELRRQACQRPLWHLGFHTYILSNLTGTIFSIGYLPVIILAPLGAVTLVFNALFARLLLGDRFSRQSAIGTFLILLGAIMIGLFGIVPEPSHSLEDLIQLWKRPSFIIYFSLIEFAVVSLLIGNRIVERMLKRNAKANLSTSQLQYHHLRSGSAASSVNPSMDEYSTHNKILDGRLGKLSSTRIKSILGISYGCVGGMLSSQALLFAKSAIELLMLTILEGKNQFENPLSWFLVIALITTALLQLYYLNKGLRLQVLVGVLVLAWRPADEGYDDRDNNGDEDTLLLPNASHPSTPKHTRVFSFKGVSGQGSGGGHLQQDSSVDAMNLIQGFEMYDSDDDDTRSIGQDRTQVQQDSGLITLAGDEDEEHPQPTYTPKSLVFAPTPRGSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0N9</accession>
    <name>A0A9P6T0N9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Peptidase A1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_009387</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000558">
        <property type="protein sequence ID" value="KAG0016165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0N9"/>
    <dbReference type="OrthoDB" id="660550at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF51">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040185025" description="Peptidase A1 domain-containing protein" evidence="5">
        <location>
            <begin position="18"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="6">
        <location>
            <begin position="72"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="90"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0016165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="390" mass="41196" checksum="8D3D09F3D9383996" modified="2023-09-13" version="1">MVKILPILLLSIACVFAAPTPKTSVKLPLKAPQSRVAYHHARSRDHCRWSHLSNNSTNSTLNIPAINADVSYLITVGLGTPAQNVDLIFDTGSSDLWVQSANYDHTQSSSSKDLKETFSIQYGSGSTSGKEFSDQVTIGGFTFTQEFGVASQATGFNGIQGLVGFGPDDLSAITSNGENIPTPTDNLYTSGQISSDVIGVFFKSITDGGTQETNGEITFGGVDATKFTGSITYVPVTTVSPASQYWGIDVSSITYGTSKVSSTTHGIVDTGTTLILLSDSSVKALYKNIRGAALDNNSGLYTIPSSQVSKLNNITFTIGGTDFTLTPAQYLVPDNQVANQGGVSGTAYSWIGSLGSNESGLAFILGQKFLENYYSVYDTTNNRVGLAPLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0W1</accession>
    <name>A0A9P6T0W1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_009219</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000532">
        <property type="protein sequence ID" value="KAG0016452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0W1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19075">
        <property type="entry name" value="AKR_AKR7A1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF4">
        <property type="entry name" value="NAD(P)-LINKED OXIDOREDUCTASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="10"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0016452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="283" mass="32171" checksum="66DD559E50A542F7" modified="2023-09-13" version="1">MSYKDERMRVILGCMTFGAEGGGARVKTNESAMEIINTFRKYGHSALDTARIYADGNTEIMMGQLDLDGLTIDTKCFPLQLGGLHPDRVKASLLESLAALRKDKVHVFYLHAPDYATPIEDTLKAVNELYEQGKFEVFGLSNYSAWEVTKIYYVCKEKGYVVPTVYQGMYNALTRNIEPELFACLDDLNIRFHAYNPLCGGVLTGAYTFQGEVEQGSRFDPHAKQGARYRERYWKKEYFEAVEVLKKACEPHGLSLVQVAFDWLQFHSKMQFARGDNSKVCRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T108</accession>
    <name>A0A9P6T108_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_009022</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000511">
        <property type="protein sequence ID" value="KAG0016688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T108"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="950"/>
            <end position="971"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="227"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="481"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="858"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1060"/>
            <end position="1104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="481"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="876"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1060"/>
            <end position="1072"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1075"/>
            <end position="1099"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0016688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1121" mass="124705" checksum="34671271FA3737DC" modified="2023-09-13" version="1">MSNLIDSFALSSHAKHGFYGKQLKVTGSVSSSPSSTGAELDLAIKIHVIENTWTTCPLLPPSTILHRWKVTLLDSPNHHIDGEDDIISDHDKTVVGATVDHSNETLKLGSYQLWLGHAKDGKRSSWVQTTVERTETISPAPSPTYEQRSARPLSTSSFSSYLPGQNAAQQTHVAVISSALCFVANKSGDYLVQLSIHVPFVAGADSQIFLAQIPKCRNNFIKFRVESPEPKKDEDGKEDLGGVDGTKDHGEHEDILGNTSDGFEFNIHPEVKPLDDSHLNPDSDEDIQFWLEVQELLVGRDKFVGKLAASDDAPKSNAETQQDSVQEPLTNGISNRFEIAGCFTPSSSLLVSWMPRNATNFVQDVEQEMTIHIAGLPDQTKSSTLLQHRKRKDPEVSHAIDQIDQEEGLIEYDHLEMDDGDLVISVEDVLTVNIQKLGWKQPFMDITIDLSDTQHRQTNDMSLLEITGDAVQDYEAIFTDNADQTSTEQTPSELENLDKESTVDHERHLPAVYRVWFFNGTEGTTVVHVRARVGQAVSVGYGKDISCNIPRIQVHGASLDKGRIHIHTSNDLVIHRCNTRYLESPPIDGHSLPDDNSSARHPPMLRFQYQSSDYQLTVIAQRYQGIARIARIERIKAEIGVSGQHHPGFARVLLTNVVLPYQDDSYLRVYQLDGAEIWNVMVDGKPCAKSIQFTERKSGSQRTIMIPISEDVSDSDNLHQVEISYGFNTVDRDQGEDLDDETVNPMIKLVVPGFNLPVGEYVVVASLPKLPKDMDYDEPVGDFEITSKLGESSQRKTITFGAYMTLGRPKLSIKASRTAFAPRSWQNVVDGAVGEAVENSDQPEILEQITRTHAHPNLIAHDPQQPPSNAGPVVVQQASQRHPQQPLDLQNPQAEQALDGEILPVLSVRPRRMEGSSVQASGQTSNLSPQVGLDSLSPRLWLEQICHAGFWWKQLLVILAAFLLVIMIINVTNFRDTMSTSLDLVHVPVWQRPFAAIGRLWYDNSHYRQGGQYSEPDRTSNEYFVRDEPVAETLQPKNTETLQPRVTETLQTRITETESVASAVTTAAETTTQDLEVRPRVASNDDRSRSDDGKNDDTRPQPVGFMKLIQMLKRMVGGAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T126</accession>
    <name>A0A9P6T126_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008934</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000502">
        <property type="protein sequence ID" value="KAG0016787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T126"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="267"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="333"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="381"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="412"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="440"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="468"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="502"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="529"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="592"/>
            <end position="603"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0016787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="625" mass="65126" checksum="C3F13CACE964FA51" modified="2023-09-13" version="1">MSEILPEMSSVTLPEILLNNVKELDTASSSLTDANMASPPPPSSTAAAASVATVIVTVNADTLETAASESAQAPDTKVESSIAPREERTPTSTSAAVKEGPDLVEQDLLIELEELRKEKSRLFSLFRAALQKKEETPPLPPPTQPSQPVEVTPISAFNSGSTLPSVAEEESQQEEETAATKTTSPSFKAMDSLRETNDVYSADRNGGFSSSSNMKDDSRRKPMNPRRPSDQDYDRRTGSPSRPNFKRREHETIDRSKLNLEIPRKPSVPSSASASSNSTASTPTPTSAAFSLHHHHPYPYQVPPFPSSSSTPSFSQKGKRQRSVSPSTPYGPGPGRLGGGGGPGEKSGGEGGRGPGAGSFGSMYSDSAPPNKHPRADYNMGSHGRSLNSGGNSNVNGGSHHSFNGLPEKPQIRHHHNHHHNSHGGGDDGYQRGKHGGPTSSSFSNMNGSINNNNSNNYINHNNNSSNSGGGGGGGGGGGGNNGNYRQGGPIRYPPPTRIGFGNSNSNNNGGHNNNSSNNNNNSNNGNNSGPGSGSGNGGGRGGYYGHGDGGGGGNNNGGGATSKFGPPNRPLPFRNMMQMNHARGMAQNRNGFGGGGGGGRVGGPPDRPMSSGRVGDWNRRRSRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1G6</accession>
    <name>A0A9P6T1G6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RxLR effector protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_007779</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000404">
        <property type="protein sequence ID" value="KAG0017915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1G6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040225912" description="RxLR effector protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0017915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="70" mass="7363" checksum="116CAF107EEEEE37" modified="2023-09-13" version="1" fragment="single">MKITLLTALVLALSSTTSASPVASSPSVITLPIRSQRTASNLNAESLTRRYLQKRGTNSTSAALTSVEND</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1H6</accession>
    <name>A0A9P6T1H6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Mitochondrial phosphate carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">MIR1_3</name>
        <name evidence="12" type="ORF">BGZ80_007993</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000420">
        <property type="protein sequence ID" value="KAG0017724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1H6"/>
    <dbReference type="OrthoDB" id="427452at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990547">
        <property type="term" value="P:mitochondrial phosphate ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000024">
        <property type="entry name" value="MIR1p Mitochondrial phosphate carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044677">
        <property type="entry name" value="SLC25A3/Pic2/Mir1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45671:SF12">
        <property type="entry name" value="MITOCHONDRIAL PHOSPHATE CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45671">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 25 (MITOCHONDRIAL CARRIER PHOSPHATE CARRIER), MEMBER 3, LIKE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="17"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="115"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="215"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0017724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="310" mass="32743" checksum="2DB377AB756F3728" modified="2023-09-13" version="1">MSTAIQTHAIAAPLGIDLYARFALAGAISCSFTHVIFTPVDVVKTRIQLDPYTYNKGMVASFRQVVRSEGVGALMTGAGPTLAGYFVQGGLKFGGYEFWKKTLINYVGPENAVNNRTSIYLIASGIAEFFADVALCPLEATRIRLVSQPTFATGLVSGFNRILREEGAIRGLYSGFGPIVFKQVPYSMSKFVVFEHVSEAIINAIGAKENLSAGAVTTVNLAAGLIAGMASAVVSHPADTLLSKVNKTSGTGSIMFRLADQARELGVRGLFLGLGPRVAMVGTLASLQFAIYGDIKKALGATGGFEIKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1M7</accession>
    <name>A0A9P6T1M7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_007360</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic initiation factor 4E family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000375">
        <property type="protein sequence ID" value="KAG0018286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1M7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016281">
        <property type="term" value="C:eukaryotic translation initiation factor 4F complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000340">
        <property type="term" value="F:RNA 7-methylguanosine cap binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.760.10">
        <property type="entry name" value="RNA Cap, Translation Initiation Factor Eif4e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023398">
        <property type="entry name" value="TIF_eIF4e-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001040">
        <property type="entry name" value="TIF_eIF_4E"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11960">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01652">
        <property type="entry name" value="IF4E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55418">
        <property type="entry name" value="eIF4e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="1" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="280"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="26"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="83"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="99"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="131"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU004374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0018286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="450" mass="46494" checksum="E1B3032645C136C7" modified="2023-09-13" version="1">MSSAHPALDGEAVSNPTNRHGHPTPASVSASVTGSRGSSSPGPWRPASLAGRSSPAFGHSSTFRDTTDNPPGIHSGMTPLRGNGSTSFPEKQRTQPVTSSGSSNYGTSSPGSAWTSPSKKSASLSSGAAPTSTLSSSAERSNGNGNEQYFTSTVSTASPAHSSLNSFARSSSAASAPMASSSAALSVPTIVADSSSNSSAGMPSGPSQKQPLNMEALAAKFADSKETKEKFAKLQLSPALSPIGLTDKERRAPMGSFATPSSSSPHFAHIKVQRTASLNQGSQNSLLPRGPGSRLQPGHLAQSTDMRRTASHNNAFSSGLGMPIGANGGGFEHSNLGSGISTNNGHNSSTADGIKPMWEDPANANGGRWIVTLLNKNPELLDRCWIELAYALVGEQLDAGDDICGADYNGFEIFWATQKLYNTRVDQKGTCSGHAANEYGAANFRSEYDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T213</accession>
    <name>A0A9P6T213_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006302</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000310">
        <property type="protein sequence ID" value="KAG0019112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T213"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="222"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="475"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="511"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="62"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="296"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="319"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="402"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="435"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="446"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="475"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="511"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="531"/>
            <end position="554"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0019112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="600" mass="66404" checksum="A8A223228623DAFA" modified="2023-09-13" version="1">MEAREGEALSLTCSVLRFNFEREHTKQSRDRQQFTQSESRIPIPKARRATGESVNRPNHGQSKLGSSESSSSKTASAPSTPRPIPKNNKKTIQPSSMSSSYTFDDSIDNPFLPSTPPAFTPSMERTGLAKPESSKESSSSFTEVPKQSTSRKPVTSNTPAASAAIADEKPPNPPFARSRNGSTSSLPKPRHEDMILPAVARRIKEEGLFDHDVIAYSDDYNAPLYKLPPASSSINNPFASYDREKAASSTSLGQQKSPLSKVKNETGSYSDQILAPSPDIPDSPNASSRQAGAPKTETQSRQRQSSEGQSGANGRDDVPTSSNNTSEVVQPERPRRARRNTNHQAQQEHANSNDEYKPRRQRRPTMSESRNNEDAHGANNWNDSREPQIASESRRNESAKINNNNNNNNNNNSEYHQNSSSQVGGSNQFHDAHTQRQGRYQQNNGDYDRSRQENHGRQRDAYNDRRGEYDSHQANAYAQNGSYAHQSNGGRYDDRQGWNNAQQRDYNAQQGGYNAQQGSYSAQQGGYNAQHGYSAQQDGHNATHGNYNNSYNGRNASLQPRTEMVQIEMSEIAPSVGGDVTKVDPKDDMKKKGKVCCVIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2B7</accession>
    <name>A0A9P6T2B7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">tRNA-dihydrouridine synthase</fullName>
            <ecNumber evidence="16">1.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="primary">DUS4L</name>
        <name evidence="20" type="ORF">BGZ80_006750</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>5,6-dihydrouridine(20a) in tRNA + NAD(+) = uridine(20a) in tRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53348"/>
            <dbReference type="Rhea" id="RHEA-COMP:13535"/>
            <dbReference type="Rhea" id="RHEA-COMP:13536"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.90"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="12">
            <dbReference type="Rhea" id="RHEA:53350"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>5,6-dihydrouridine(20a) in tRNA + NADP(+) = uridine(20a) in tRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53344"/>
            <dbReference type="Rhea" id="RHEA-COMP:13535"/>
            <dbReference type="Rhea" id="RHEA-COMP:13536"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.90"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="14">
            <dbReference type="Rhea" id="RHEA:53346"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>5,6-dihydrouridine(20b) in tRNA + NAD(+) = uridine(20b) in tRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53352"/>
            <dbReference type="Rhea" id="RHEA-COMP:13537"/>
            <dbReference type="Rhea" id="RHEA-COMP:13538"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.90"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="13">
            <dbReference type="Rhea" id="RHEA:53354"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>5,6-dihydrouridine(20b) in tRNA + NADP(+) = uridine(20b) in tRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53356"/>
            <dbReference type="Rhea" id="RHEA-COMP:13537"/>
            <dbReference type="Rhea" id="RHEA-COMP:13538"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.90"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="11">
            <dbReference type="Rhea" id="RHEA:53358"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a 5,6-dihydrouridine in mRNA + NAD(+) = a uridine in mRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:69851"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:17789"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="9">
            <dbReference type="Rhea" id="RHEA:69853"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a 5,6-dihydrouridine in mRNA + NADP(+) = a uridine in mRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:69855"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:17789"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="10">
            <dbReference type="Rhea" id="RHEA:69857"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 16 18">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the Dus family. Dus4 subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="16">Belongs to the dus family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.-" evidence="16"/>
    <dbReference type="EMBL" id="JAAAID010000335">
        <property type="protein sequence ID" value="KAG0018775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2B7"/>
    <dbReference type="OrthoDB" id="9977870at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102266">
        <property type="term" value="F:tRNA-dihydrouridine20a synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102267">
        <property type="term" value="F:tRNA-dihydrouridine20b synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000159">
        <property type="entry name" value="tRNA-dihydrouridine synthase 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001269">
        <property type="entry name" value="DUS_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018517">
        <property type="entry name" value="tRNA_hU_synthase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11082">
        <property type="entry name" value="TRNA-DIHYDROURIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11082:SF31">
        <property type="entry name" value="TRNA-DIHYDROURIDINE(20A_20B) SYNTHASE [NAD(P)+]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006621">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01136">
        <property type="entry name" value="UPF0034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 16" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 16 18" id="KW-0288">FMN</keyword>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0521">NADP</keyword>
    <keyword evidence="18" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 16" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 16" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="DUS-like FMN-binding" evidence="19">
        <location>
            <begin position="30"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="17">
        <location>
            <position position="115"/>
        </location>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <begin position="32"/>
            <end position="34"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <begin position="237"/>
            <end position="238"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00050434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00051779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00051932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00052996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00060741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRNR" id="PIRNR006621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR006621-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR006621-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAG0018775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="329" mass="37240" checksum="0AE489B42A686DA0" modified="2023-09-13" version="1">MPFKDPSQRSIPRTDIMQLFSTRNRPLNVCAPMVRYSKLPFRELVRRYNCDIVYTPMILADVFSASNYSRECEFSTNMLDDPVVIQFAASNGVDLANAAELAAPYVSGIDINCGCPQKWAINEKIGAHLMSDPESVRDMIRMTKARVNVPCSIKIRIHKDLRETEEFVKRALSVGVDFITVHGRTRRQKSTEPVSLEGMRFVKEVSTVPVLANGDVFSIDDAKMIVDATGVDGTMSARGILENPALFAGHKTTPWECIEDYVDLALSYGTNAFIFHHHLMYMFENTMSNAERRTFNSLTTIPSILDYLEEHYGLDIAQKRNRRRTAILI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T318</accession>
    <name>A0A9P6T318_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_003311</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000187">
        <property type="protein sequence ID" value="KAG0020946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T318"/>
    <dbReference type="OrthoDB" id="2213137at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17352">
        <property type="entry name" value="MFS_MCT_SLC16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF284">
        <property type="entry name" value="EG:103B4.3 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="75"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="115"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="170"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="202"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="232"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="311"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="345"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="376"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="401"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="436"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="470"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="4">
        <location>
            <begin position="79"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0020946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="510" mass="54466" checksum="ECC48601F691110C" modified="2023-09-13" version="1">MEPPHTPIEKISQPDKLSITLAMANTTTVSSSDISDSKKEIDTSTEIALESTLSPSPPVPSESLKPSLLEGGVKGWLAVLGSLLIHCFVFAPTEFVFGVFVLHYQDVFPGSPASAIAFVGTTGSAITYIAGFLSGILADRFGFRPTAFAGSVIMALSLVGASFSTQLWHLYVTQGVLFGIGASFAYYPAIAVPSQYFVKHRGLAIGIAVSGTGLGGFGLAPLTNALIDMVDIFWTLRILGMMILVVCGGASMLIAEKKVNPVEYEEEQQDQERTMIGESFKATEATDVEIEVKNNKPSFFQALHVFKDPQFLSLTLAELTASIGYLIPLYFMQTYAVYIGLSAEQGAFILGLSNGSAFVGRILLGIIADRVSNTKTLLFCCWATAFSVIVFWTFAKSFGVLLLMGMTFCMFVGAYVSLVPVAVAESFGTDTIASMIGLMYGAGGLAMWGGSPLAGYILDSTLPNLSYTPVIMTAGISLVLGAICVTSWAYFHWRATRPVANGGHTKDRTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T361</accession>
    <name>A0A9P6T361_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">separase</fullName>
            <ecNumber evidence="2">3.4.22.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_004133</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>All bonds known to be hydrolyzed by this endopeptidase have arginine in P1 and an acidic residue in P4. P6 is often occupied by an acidic residue or by a hydroxy-amino-acid residue, the phosphorylation of which enhances cleavage.</text>
            <dbReference type="EC" id="3.4.22.49"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.22.49" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010000214">
        <property type="protein sequence ID" value="KAG0020475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072686">
        <property type="term" value="C:mitotic spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044732">
        <property type="term" value="C:mitotic spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004197">
        <property type="term" value="F:cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051307">
        <property type="term" value="P:meiotic chromosome separation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005314">
        <property type="entry name" value="Peptidase_C50"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030397">
        <property type="entry name" value="SEPARIN_core_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12792">
        <property type="entry name" value="EXTRA SPINDLE POLES 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12792:SF0">
        <property type="entry name" value="SEPARIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03568">
        <property type="entry name" value="Separin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51700">
        <property type="entry name" value="SEPARIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase C50" evidence="6">
        <location>
            <begin position="2457"/>
            <end position="2552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="92"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="166"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1761"/>
            <end position="1793"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="103"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="204"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0020475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="2674" mass="300516" checksum="30A91796409228B8" modified="2023-09-13" version="1">MSTSEFGRIDAKQQARLDAFIDALSDHRHYHANLVPELRELLSSVQSSAPQSQAHKAKNTNAEALGKQIKRLFNQSLSTLTKWSELLEASDASNVVPRDRSNDTTNSSRLNATNDKPAVAIGPVSKTQQMVSQTVTATSTISTSNITANENTGTKPLTGAAIKPTKTVTTTRNQTKAKEDMGPQKRAGQMHGARKNVDLDNSKTETPPRTSKSTGTTVISRQLVAKIEISTPTAALSISDEKSIYETDQPTYAHIAVLVDIGFLGVRTLELMGGYISTNLFEIEKARSNLISKIIQLGMKKRALQELGYLREQLIQCAISLWKERDLGTLDEQERQRSKSKIESGSVIPSSSSSVDSIKKSYQHLFTFPFPKALSTFAANSMPNALSATSVGLEQVLTFIRLVQALHNNAVRCWMDVRNGSLAYLLPEMMSQPNSPYDWCMCIANIHRQAGQQSLDALFRLLFIAAGKAVDIDPTREGHRHAFMLRMHGIKYHGLYRHLTETKDGMIWDKILRCGAEFEKSTRDGQTREDVLLLLRSYKTIYEFLGEFAAVDTSNARFLEWRKHFVHLSSKVDDTVIRIFAKSLQGDDQDMEMVDVATTKEPQPFTLSRHGTSPSMECDTRLKVVPIPRPITEPTISGIVIPVERVLSRLDDAVKALQKFEDSLQHWHTTLSSEKDLDSNMEKVKNALLVLEQDLSSFPPKGLPTSILQNVARIFRSMDNIRSVGSKIMDKYEKEQKRISTDSTSDVDVALRSLVSAGMVTRILSDVTVGLWHYARLDYQVGFEVKQIAWTLFNSNPKATPDPAKLSCARVDAILFLFRLYQSDIDSLRILDSPSILGYLESAFSTAKEMNDDESLPWISNALYNLGGALFKADRRKEAIRPLEAAVVCYLHWLRDDLGADSSLSDSNTTKNPKTEARLVLANRYEVLGVCSQSINDLSHALDCFNSGLCVLPLNSFRGIDTVALGELKTSQLPAAKLLNRRTRILLMMEEPRFTSVVTSVQEFESKVTKHDVPVHIRGIVQEFECGLLSVLSVKTNQVSRRNKEQIEILKHLMTRVYRGGRSLMNPIRRARVLVQLAVLYQAHSDMDLQQEAQHLIEEAIEILKERDLKADIELEHVRNYNLAFAYSWNGILDRSRGTGLSRKSKPFQIALQLWEIILSDIECFTSYEDTQLANHQSKVKKLRKHLPEPEILYDHLQMLADCLGMIDYRVLQVQVYFLMLRLCNGVLAMTEETCADAVRIYSRIGQAYLALGYSGKAKMALNHGKLVLEEMARTSKGSTLRGEVYATWLLVYSLYLTSVGYKAQGISAYNQAKYHSDQHQLLVGTREGVIGPLSKSGALSRKIEAKVYRAMIVVEASLARSQLLYYEGNLSEAISDSKRAGRQLSRIVSTLSTAIKTAQADPATVAARPMDNPFLVQGQTADQSEGQVQEQTWSENQQLRQGLEMLATQRFQWSIFRLLIEAYHQLGKLYLIQGSAREAEYFFVEGKHIATLSKAGKSLDRFMLDQAELQLRQHEWQGCQQTLEELSMQEDELNAGALSWEIQDARIQLLRGDLYFETDQFELSMQAYFRTDDVLSHLMDKSFISGLEQLVIREPQTPREAKLVTIGRRQGMGGSEILHWRSDASLGSRESGTPDQAQFECVTLGSIKAAIGYRTGLILGLEGRRVQAYGLIEDSKAEDPMAFTVAEYHFTKARLLILELEDAMAKHLMYALIPESALSVGLFKKTRTQKLESPPGSFNQSPVLNDSGIHALLGFSRDSHLSSPSVRVTRMTRRRRSQPANEPPSPNLSETRTNAHQAIGKDIVNQYHEILRKAREHLSAAYKHSIQIYSPHIISDICSKQVYLSVLESCFHQEGFQERVSSLGEPIGIRRDSHWTMATRAACYLEMAKAVTQHREMHGLIKQKLNPDSAQGDQSWPRDIQIKDQFIRSDQHQQMKTSRSKKEPRLQRIGSKTINFIGLEKPRRLVLLENTDGEGEQTAEANINVKMEEDEDMDLEQVGMKLEDLNSRRGKREYFNRQSQLHSSISLGNERSFLEIMDKVYERDTLIMEEQPETFQRDFVDILPDQWTVVSLSMDVEHEVLYVNRLRANSMPLVVRLPLNRAQLREGDDQNLGLRPIVGFDEEDELEPGPPLSYKEAAEELQEILRGSQETLALTSSKYHANIAGLTGQATQKPIELTREAKAEWWSQRQELDDRLCALLGCMEDQWLCGLKGLIQSHNTPSDEGNLIGFKKTLDWIMSQAVNSMSSVSSVFGTRASGQQSSASRKGLLVQFEINIDLCRVILHLGDQPTSAELKDLIYFLLDAYLYNNMNSSVASSTSAFGDISMSSSPTPPTIEYSEVQFGRIALQIKEALRCYWEAETVAKNNGFDEGGHVILILDKHLQGFPWESCPVLRQEAVSRVPSMWFLRDRILQQRYNLSKSNTEDPFSGSSSSITSTNVEARHPWDCKWQDLELDPQKTFYVLNPGGDLKNTEDAFKDYVKTQQGWDGITGRAPLDLECINGLSNNDLYIYFGHSGGEQYIKSTQIRQLGHCAVSLLLGCSSGSLKSEGEFDPTGNAMNYLLAGCPAVVANLWDVTDKDLDRFSMAMFSLWGLAANRYNSMPDKSRSQVDIDEMDNSHVERIGSERAESINGLRLSLVEAVKEAREECKLKYLVGAASVVYGIPCFLKGSNNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3I8</accession>
    <name>A0A9P6T3I8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_000772</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000117">
        <property type="protein sequence ID" value="KAG0022201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3I8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0022201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="474" mass="53973" checksum="63B31EE1DA7AEF0F" modified="2023-09-13" version="1">MSTPKKSTWNRIFRKKSPVMPLAFIRKPFEQLEHSLMAGQTPALETLSVRVQNQDPNLILRLPASTVHNLQISTRGNPARKPRLYMEDVLRAYPNLVKLTLEGLYTLTTHLSDESQDGGASSSSSGQFLAHTHLPLFTASTASGTMLETAAVTTENGQPFSLPASSSSSTNRGNKGKDKSIERSSSIQTLNLRLVDISQDNLVALSELLPRLRSLLIEEFLVPDMMIKIYRWVWTPKFIHSLRDGFPHLRSLRLAIPFDCIKEDAIVEILKSFPLLTTVGFRNSHFGKLAMETLQEHCKHVECLDVSFGCADREFKGALLRFLQSWPKLRELEADGVIFHLDTPMDDDVPRAQWACTGLEKLVCGFQGTESMIFEHLSQFPRLSNLTISYPSLNIFPVESNLTWMAKLTRIEYFWFSQLRHQPLDKATITWILNHWPNLRKLHIAGGVLEQKDTVKRWCRDAQRFSLVVEYDRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T484</accession>
    <name>A0A9P6T484_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">V-type proton ATPase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">VMA6_2</name>
        <name evidence="6" type="ORF">BGZ80_008585</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments. This subunit is a non-integral membrane component of the membrane pore domain and is required for proper assembly of the V0 sector. Might be involved in the regulated assembly of V1 subunits onto the membrane sector or alternatively may prevent the passage of protons through V0 pores.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the V-ATPase V0D/AC39 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000047">
        <property type="protein sequence ID" value="KAG0023671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T484"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033179">
        <property type="term" value="C:proton-transporting V-type ATPase, V0 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1690.10:FF:000001">
        <property type="entry name" value="V-type proton ATPase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.50">
        <property type="entry name" value="ATP synthase (C/AC39) subunit, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1690.10">
        <property type="entry name" value="V-type ATP synthase subunit C domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036079">
        <property type="entry name" value="ATPase_csu/dsu_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002843">
        <property type="entry name" value="ATPase_V0-cplx_csu/dsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016727">
        <property type="entry name" value="ATPase_V0-cplx_dsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035067">
        <property type="entry name" value="V-type_ATPase_csu/dsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044911">
        <property type="entry name" value="V-type_ATPase_csu/dsu_dom_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11028">
        <property type="entry name" value="VACUOLAR ATP SYNTHASE SUBUNIT AC39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01992">
        <property type="entry name" value="vATP-synt_AC39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018497">
        <property type="entry name" value="V-ATP_synth_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103486">
        <property type="entry name" value="V-type ATP synthase subunit C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="4 5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR018497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0023671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="337" mass="38774" checksum="B6433B9AFDA55FCC" modified="2023-09-13" version="1">MEALFFNADDGYLEAVIRGYRSSILNNTAYINLTQCETLEDVKLQLAASDYGPLLQNEAHISTSLLAQKCTEKLVQEFNYIRAHAVAPLSHFLDYLTYAYMIDNVILLITGTLHERDTHELLERCHPLGVFESMPALCVATNVAELYNSVLDCLSAEDLDEMNIEIIRNTLYKAYLEDFYQFSLSFGGPTAEIMGELLQFEADRRSLNITINSFGTELTKDDRAKLFPHIGRLYPEGNLRLAKSDDIDQVKAVCDVFLEYRQFFDGTTGTSATKTLEDRFFEYEVHLNKKSFQQQFHYALFYSFLKLKEQEVRNIVWVAECISQGQKERINNYIPIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-06-18" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T4G8</accession>
    <name>A0A9P6T4G8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BGZ80_003720</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000020">
        <property type="protein sequence ID" value="KAG0024375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18580">
        <property type="entry name" value="ABC_6TM_ABCC_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000013">
        <property type="entry name" value="ABC transporter C family member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000997">
        <property type="entry name" value="Multidrug resistance-associated protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000163">
        <property type="entry name" value="Multidrug resistance-associated protein member 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044726">
        <property type="entry name" value="ABCC_6TM_D2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF443">
        <property type="entry name" value="MULTIDRUG-RESISTANCE LIKE PROTEIN 1, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="22"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="147"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="221"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="317"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="781"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="826"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="941"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1027"/>
            <end position="1045"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="214"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="449"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="787"/>
            <end position="1080"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="1116"/>
            <end position="1397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="426"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="682"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1184"/>
            <end position="1221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="431"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="682"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="721"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1196"/>
            <end position="1208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0024375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1404" mass="157451" checksum="5111746036714FC5" modified="2023-09-13" version="1">MLLVSISMFTQAIYEIHSTEFVLAQAIGSLTMGTAWLVGLAVNYNEHKGSTRVQQQSGTQEYEKANLWSRLTFTFFQPIISLAAKQHILVPSDIVNQLPDSHNTKSGYTVLSTHWFRRVTNYRDKVLSAKKNGYSEEEIKKIKKPNLMATIFIAHWKALVPIIIMRIFIPFTDYLSPALLGLLLDYIGGDTLDESSAPTFISPKQEEKPLTYGLAIASSMFAIHVITTMMLLGWSFLAGLLTLLALVPLQVWRAKVFEGLEDERLNATDERVRLTSEVLSNSKVIKLYGWESAFKRKILAARNLELGILRNIGAMEALMSVVFASSTVLVGLVTFAVYVTLGDGVLTPKVVFVSFSLFQLLHEPVGRMAEGTSDTISLVVATKRIQRFLFREEINDTQDVRARFCEEDSRNVVEIRDATMTWTLGRSSIESSDDEDSDVDEEREDEQSLLSEHMGEAVVNGDPITRATLRNINLTIQEGAITIVVGRVGQGKSSLLSAIIGEMYKLHGTIRVRGKVAYVPQQAWIINATLRDNILFGSAFDQERYRQVLETCGLEPDLAVLPAGDMTEIGERGINLSGGQKQRVSLARAAYQDADIYLLDDPLSAVDAHVDRHLWENLIGPNGILKDKARVLVTHGIHHLEHVDQIVVVKEGEIAEVGRYEDLMAAKQSFYQLIEEYSTKRARKRRGSHATHRVDGLGNQPLSKSDESSLRGTVDNDIDSDSVTIENTSVDALNKTDTQTRGRDAEGEEDDDDMEDELIADEVMKKGGVEWRLVKNYARAFSLKVSVGMILICMVTQLCTIGFSLWMKYWISKTKEELEKSLVLFLGVYSAMVLVYVVFFILFVHLALAVGRIRASEKLHRLLISTVIRLPMSNLKTYICANVNVSFFDTTPLGRILNRFSSDMYSIDEHLGWKTMDMTYITISVTSTLVVIAATTPAFVFMIPIIASVFYFIANWFLWATRSLKRINSVSLSPLYQHFDESLNGVSTIRAMEVQQQFIEESDNRTDYHANAYTTYMYCNRWVDFRLQVLSAFIILVVALSGVFARNTIDASLIGLSLSFAIAQTDEIMWICKDFTEWQSHLVAIERIQEYTDKHTEAPETSATVIPESWPEQGRIEFQNFSARYREGLDLVIKHLSFEIQPCEKIGIVGRTGAGKSSITLALFRIIEAANSPWARASDNAGYHERVQGDGGENEPLLRRHPDSRSQDGGDEDEEMDGGSIKIDGIDISTLGLTELRKHLAIIPQDPTLFAGSIRDNLDPFQEVPDSALWEALERAHLKDHIRSLPGGLSTEVAQNGENFSVGQRSLICLARALLRKSKILILDEATASVDVETDELIQQTIRKEFQDRTILTIAHRIKTVMDSTRILVMDRGEVVEFDPPEVLLQKPESLFFKLAHQAGEATM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T4Z4</accession>
    <name>A0A9P6T4Z4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Emp24p/erv25p- protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ERP1_1</name>
        <name evidence="10" type="ORF">BGZ80_007719</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the EMP24/GP25L family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000004">
        <property type="protein sequence ID" value="KAG0024784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T4Z4"/>
    <dbReference type="OrthoDB" id="3427at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015720">
        <property type="entry name" value="Emp24-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009038">
        <property type="entry name" value="GOLD_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22811">
        <property type="entry name" value="TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01105">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01190">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50866">
        <property type="entry name" value="GOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040257476" evidence="8">
        <location>
            <begin position="25"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="GOLD" evidence="9">
        <location>
            <begin position="34"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0024784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="219" mass="25277" checksum="8A17899EFEF3C988" modified="2023-09-13" version="1">MAFNYTRWTIALLVLLSILPSVFSLYFYLEGAEQKCFTEELPKETMVTGDYNAEEWNEETKRFITNKDLQLEVVVEEMPEGNRVYAQKLAPHGKFKFTSAESGQHLICLFTASAGWFSSSKIRVTLDLAIRDILDDPEDTNEGTLSNLAQRVRELNHKVGDIRREQSYLRDHESEFRDKSEATNSHTVTWTIVQLIVLGLTCTVQLRSLRKFFETKKLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T5U3</accession>
    <name>A0A9P6T5U3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_007718</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000004">
        <property type="protein sequence ID" value="KAG0024783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T5U3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010945">
        <property type="term" value="F:coenzyme A diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03426">
        <property type="entry name" value="NUDIX_CoAse_Nudt7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045121">
        <property type="entry name" value="CoAse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12992:SF11">
        <property type="entry name" value="MITOCHONDRIAL COENZYME A DIPHOSPHATASE NUDT8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12992">
        <property type="entry name" value="NUDIX HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="7">
        <location>
            <begin position="1"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0024783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="194" mass="22278" checksum="DA1970E21A637F64" modified="2023-09-13" version="1">MMSSVPRTPIQFDRVFLDMVKSRLEEEKHQIGYQFDYDQDKPFREAAILMSCLAAALREVEEEISIPSNDVEVLGEYTPIPNKDGTMCVYPYIGFIRKPINDVSEIRYNPDEVSKVFSVPIEDLLNPEKRKHLVRFRDSKYMYPVCHVEEEGCTIWGLTAFIMDGALRRIMKQGPVGALICPEGANIPNYRPTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MCM5</accession>
    <name>A0A9P6MCM5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ATP citrate synthase</fullName>
            <ecNumber evidence="2">2.3.3.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ACL1_2</name>
        <name evidence="11" type="ORF">BGZ80_008737</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.8" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010004843">
        <property type="protein sequence ID" value="KAF9992062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MCM5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003878">
        <property type="term" value="F:ATP citrate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="entry name" value="Succinyl-CoA synthetase domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032263">
        <property type="entry name" value="Citrate-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056749">
        <property type="entry name" value="Citrate_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16114">
        <property type="entry name" value="Citrate_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24948">
        <property type="entry name" value="Citrate_synth_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ATP-citrate synthase ATP-grasp" evidence="10">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-citrate synthase citrate-binding" evidence="9">
        <location>
            <begin position="125"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF24948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAF9992062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="169" mass="18306" checksum="2049BE531397FB5E" modified="2023-09-13" version="1" fragment="single">GIEVGDVDAKALKFQVKVQDPFPSSESIRSSLLVNVPESKHDVLVDFITRLYAVYVDLHFTYLEINPLVVLDPTAEEPARVYYLDLAAKLDQTAEFQNIGIAGVVPSSTGADAGPAMDFPAPFGRELTKEEAYVQELDSKTGASLKLTILNKDGRIWTMVAGGGASVVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MCQ0</accession>
    <name>A0A9P6MCQ0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_008662</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004776">
        <property type="protein sequence ID" value="KAF9992191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MCQ0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052394">
        <property type="entry name" value="LRR-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24114:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24114">
        <property type="entry name" value="LEUCINE RICH REPEAT FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9992191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="172" mass="18666" checksum="45EFEBDDE7B2F56A" modified="2023-09-13" version="1" fragment="single">LVVIPVTFFIFMTKMFRTHALDLHEIRSIIASSLGLKDLTSCARVSRDWNNSFTPPLYNSVVLSKHGPNMESVEKNKHLIKRLEIQSAAYEKLASTSARGKVISSIIANSTLAILIMNNNSIGDNGAQALSEALKTNSTLTTLSLWHDSIGPNGAQALSEALKANSTLTTLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MCU4</accession>
    <name>A0A9P6MCU4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_008672</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004787">
        <property type="protein sequence ID" value="KAF9992165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MCU4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9992165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="66" mass="7680" checksum="5A7AA4F3BAD00050" modified="2023-09-13" version="1" fragment="single">MEAYSQGYFDLGYTTVGIKLSWDEEAQQKKIGFKKLWQHATLENWREYFEERSDNGVAIITGEASD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MCZ5</accession>
    <name>A0A9P6MCZ5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008481</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004600">
        <property type="protein sequence ID" value="KAF9992627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MCZ5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="44"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9992627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="159" mass="18020" checksum="850C513FA43741F4" modified="2023-09-13" version="1" fragment="single">MLVQALDILDEAKRSRAEQDSSGYKKTEGGRQYSHTGRSTSPGKPELSKSMSPEPEESRREPSPEEDQNDGYQESDSDHLSENDAPLGGKRARERRMEIHGDEDDDNCKVPKLIRGRGRDKSTRYMPWIDRQRKGLIDPPSSSPTSPAPKRPKRQKRSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MDX7</accession>
    <name>A0A9P6MDX7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007899</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004137">
        <property type="protein sequence ID" value="KAF9994172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MDX7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9994172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="69" mass="7438" checksum="3B9186B66874EC4E" modified="2023-09-13" version="1" fragment="single">MVIDHQGSREDMPGEGQGYTDHSILDECALVPYHLSHVDHQASPNSKGHDVTSTGQQSTHSGEPNVVTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MHH2</accession>
    <name>A0A9P6MHH2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006396</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003159">
        <property type="protein sequence ID" value="KAG0000230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MHH2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="58"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="266"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0000230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="317" mass="34646" checksum="E6DA0762841EC3A8" modified="2023-09-13" version="1" fragment="single">MALYDPSNTMPTTVATTGAATNDPATLAGPPMFYRSYSAPSHIFMSGQQTGQDFAYSQQQQQQQQQQQQQQQHQLNHHFQTSASMPSFSQACNAPHPFQMQPSLQSPPMMRSNTNYIYHQSPVHPLQMETVSPSSLNNAGAARFPLEIPNDPFPRQTNPIFAHDMDDVQASNPSYSPPSSSLDSASPTFEAPFVSPYVAMRSAGRVHSVSIGLDENDISPLELPEEFAVYHHLTRHGSVDSLYPLIHHHEYAQSRFDMSTAMVPSLSSTSISSNSSHSPTPMLNNGANAVVSVGKETGGQSKPKQRRASMSPDSTGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MHV0</accession>
    <name>A0A9P6MHV0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Vacuolar protein sorting-associated protein 28</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">ESCRT-I complex subunit VPS28</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_006222</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Late endosome membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the VPS28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003062">
        <property type="protein sequence ID" value="KAG0001197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MHV0"/>
    <dbReference type="OrthoDB" id="2671at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000813">
        <property type="term" value="C:ESCRT I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031902">
        <property type="term" value="C:late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044877">
        <property type="term" value="F:protein-containing complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043328">
        <property type="term" value="P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1130:FF:000001">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 28 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037202">
        <property type="entry name" value="ESCRT_assembly_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007143">
        <property type="entry name" value="Vps28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017899">
        <property type="entry name" value="VPS28_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037206">
        <property type="entry name" value="VPS28_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017898">
        <property type="entry name" value="VPS28_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038358">
        <property type="entry name" value="VPS28_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12937">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING 28, ISOFORM 2 VPS28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12937:SF0">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 28 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03997">
        <property type="entry name" value="VPS28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017535">
        <property type="entry name" value="VPS28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140111">
        <property type="entry name" value="Endosomal sorting complex assembly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140427">
        <property type="entry name" value="VPS28 C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51310">
        <property type="entry name" value="VPS28_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51313">
        <property type="entry name" value="VPS28_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0967">Endosome</keyword>
    <keyword evidence="4 5 6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="VPS28 N-terminal" evidence="9">
        <location>
            <begin position="39"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="VPS28 C-terminal" evidence="8">
        <location>
            <begin position="157"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="14"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="19"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR017535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0001197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="256" mass="28333" checksum="311C88CA5E224713" modified="2023-09-13" version="1">MAYSSTKQYLASVNGANGSSSPVPSFSSTSFGASSSNSRAVPTINLDEEIKLTTNNRERAQMDNMADLYSIIVVLEHLEMAYIRSAITHTEYTRTCPQLIAQFKTASNLLGDVVPDLEKFMKEYNLDCPAAVKRIKIGVPATVEFGDGASNEGNGHRNFKYVAETVQNYITVVDALKLGMTAVDQIHPLLADLMQSLNNVPSLPADFEGRAKLREWLIKLNSMRASEELGADEKRQLEFDLVSNYTTFHGWLDDPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MI44</accession>
    <name>A0A9P6MI44_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cyclin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_005975</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the cyclin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002945">
        <property type="protein sequence ID" value="KAG0002450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MI44"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019887">
        <property type="term" value="F:protein kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051726">
        <property type="term" value="P:regulation of cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd20537">
        <property type="entry name" value="CYCLIN_CCNO-like_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000010">
        <property type="entry name" value="G1/S-specific cyclin Cln1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039361">
        <property type="entry name" value="Cyclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004367">
        <property type="entry name" value="Cyclin_C-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048258">
        <property type="entry name" value="Cyclins_cyclin-box"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10177">
        <property type="entry name" value="CYCLINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02984">
        <property type="entry name" value="Cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01332">
        <property type="entry name" value="Cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00292">
        <property type="entry name" value="CYCLINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="3 5" id="KW-0195">Cyclin</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-like" evidence="7">
        <location>
            <begin position="115"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin C-terminal" evidence="8">
        <location>
            <begin position="210"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin-like" evidence="7">
        <location>
            <begin position="214"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="349"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="436"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="392"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="436"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0002450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="521" mass="59314" checksum="408FE4CFE0ACA786" modified="2023-09-13" version="1" fragment="single">MNGVVRIDSHQGHVMAMKKKSATTHSSPSKGHHAPRAVHPTLNSAPVNAPPSLVSNAMTSTAGWAKGETDDLLELEYKEEIFQYMKQMEKETMAVPEHMDLQPELTWDLRPLLVDFLIEIHNHFNLQPETLYLAMNMMDRYLSKRVVYKKHYQLVGMTSLWISSKYEDSKEKLPSVSQLCKLCSNTYDEAAFITMERHILKTLDYGLGHPTAEAFLKKDLEMSGEDDPILRSVAQFLMELTMFQRCFLSFGSSTVAASALFFARTICRKQIVVPSDPNVFTCIQYLDNSLTNVSKTVHEKYARSRFLQASIVVKEWVDNGGRALIQPMSTTECSNPIWTLSNMLWQPPSPIPTTFPTQGSIGTPAEAQPAYNSAGYASQGHSQQQQSQQQHQHQHQHHQHHHHAQQQQQQQQQQQQKQQQQQKQQQQQKQQQQKQQQQQQQQRQQVPHQMSTGRHHSHSVSSVHSQYGHHQRTGSSVSVHHVAYAAMPQQPQSAVITHQTSYDIHPAVPDCGSRWVDVSVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MIB1</accession>
    <name>A0A9P6MIB1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Integral membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_005903</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM170 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002907">
        <property type="protein sequence ID" value="KAG0002853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MIB1"/>
    <dbReference type="OrthoDB" id="2131401at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019334">
        <property type="entry name" value="TMEM170A/B/YPR153W-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22779">
        <property type="entry name" value="SD17342P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22779:SF6">
        <property type="entry name" value="SD17342P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10190">
        <property type="entry name" value="Tmemb_170"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="73"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0002853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="139" mass="15687" checksum="2BB4A48ECA34D6F6" modified="2023-09-13" version="1">MAQGFLPPSDYTTPPWPSLYWPITDPLGHGIFMYYRRDIWLFTTYWTLIFIGSIYTLAGFWACLVFGRKHYKWAILLPVIFSITGAVIAFVSGSLVGLAIAVIYNAGAYRMSTWVPFLWGLIQALVVIMGSYSTVTTIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MK89</accession>
    <name>A0A9P6MK89_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNA helicase</fullName>
            <ecNumber evidence="3">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BGZ80_005334</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA2/NAM7 helicase family. SDE3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="3"/>
    <dbReference type="EMBL" id="JAAAID010002638">
        <property type="protein sequence ID" value="KAG0006151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MK89"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032574">
        <property type="term" value="F:5'-3' RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031047">
        <property type="term" value="P:regulatory ncRNA-mediated gene silencing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18038">
        <property type="entry name" value="DEXXQc_Helz-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049080">
        <property type="entry name" value="MOV-10-like_beta-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026122">
        <property type="entry name" value="MOV-10/SDE3_DEXXQ/H-box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45418">
        <property type="entry name" value="CANCER/TESTIS ANTIGEN 55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45418:SF1">
        <property type="entry name" value="CANCER_TESTIS ANTIGEN 55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21634">
        <property type="entry name" value="MOV-10_beta-barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0943">RNA-mediated gene silencing</keyword>
    <feature type="domain" description="Helicase MOV-10-like beta-barrel" evidence="14">
        <location>
            <begin position="306"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="12">
        <location>
            <begin position="450"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="12">
        <location>
            <begin position="617"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase-like C-terminal" evidence="13">
        <location>
            <begin position="721"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="16"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="954"/>
            <end position="990"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1010"/>
            <end position="1047"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1082"/>
            <end position="1164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="16"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="960"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1027"/>
            <end position="1038"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1097"/>
            <end position="1110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1119"/>
            <end position="1164"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF13086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF21634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0006151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1164" mass="130666" checksum="821D3F0BEA50154B" modified="2023-09-13" version="1" fragment="single">MLNLELMELLQNYDKLNTSPGQGKSVTTSEAGSPVDGTTTPKRQESFERSSALKDITEWIEKHKDYLLREQPELLVPRQIDFGNINPKAEPVHKTIRIENHGTQIVQLQARSIIPNAYDQLTCHSLEPIYAHPANGTEPMFGNIDVSLSAGSNLGFFSSWLLILVNESSLIGREITWNVTNNTQLEREMDPYAKAFTPAWCRSLNLRSAHMVVTGNAVDTIDFQEYLKAADHPCYKKHNGKFSLEPPVVESLEAILPGKITIDLSADTYASRLLPLLKVEQHLIDEDVSSYNLYMVEIKLTKLQDSPLHYFQIQVSGLSERCPLLLRGDAIIVRQVTNGRFSGVEYRTFVHGTNMRSNSVYVHLPIGALPTLANERWNVQFKVNNNRIREMYRAVSGVQEFIGYHPRNPSGDGDGDQFYSPRSFLFPTIHDAKPKVKLPNLTLQFIDPSLNWEQKAAVQSIIRNDYGLVPFIISGPPGTGKTKTLVETAFQIWRNDSKSNILITAPSHSACDTIMLRLISHLESGLLESDHLESKYLFRLNGPTRTFAEVPLPIMPYCCGTAYFDMPPLDKLLQFRIVVCTCADAGLLISSGASNLSLREYKAHKGISNEEDLKHPHWTHLLIDEAVQAIEPETDIPLLCVLDESEIPPQIVLCGDHQQLGPKTFLPELQLSFLERLITTEPLYRDHPQSRQLARPKGASNIRAKELKDTEYLGKTIPAFANLVQNYRCHPKMLMMPSAMFYNDTLVASADEAKTNSMLGCPVLPNPECPIAFVGVNGMDASNVDEAISWYNTEEAEKVASIIESLLKNSNENDEFHVEVTEIGVIAPFREQVKLLRQVLRSRGLAGVNVGTVEDYQGQEYRIMFISTTRSRAKYLDQDVRQGLGLVHFRKRFNVALTRAMAMLVIVGNPELLKQGMIGRLEMNSFVSQFVENLDRSRWLGGNVEADEEGFIVVPSGSDSELEDDDQVDEDEDEGLGGGESENGYEENQEYNQSLEGLSHALTHELDLNGKMTQNGGQRFGGQNLIRVKDAIPESSDRGEDEDDETRAAREQLAIGSLNIDEDTPELQKLALNHTNVLSLTRDGAGGRIPADRRPNNHQLSHSAMSSIGGNTEAVFRSQQLPDYLSQQQQQQQYQQYQHPQQQQQQQQQQQQQNLPHQLPMHSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMC8</accession>
    <name>A0A9P6MMC8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BGZ80_004571</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010002315">
        <property type="protein sequence ID" value="KAG0007521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMC8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05123">
        <property type="entry name" value="STKc_AGC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000008">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000524">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017892">
        <property type="entry name" value="Pkinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045270">
        <property type="entry name" value="STKc_AGC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24351">
        <property type="entry name" value="RIBOSOMAL PROTEIN S6 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00433">
        <property type="entry name" value="Pkinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="65"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="14">
        <location>
            <begin position="358"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="403"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="443"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="487"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="403"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="488"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="509"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="614"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0007521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="614" mass="68288" checksum="EF829FA3510980F8" modified="2023-09-13" version="1" fragment="single">TEDGREPAKRFLGQVKLSPSEIHNRTIDSWFRLQGREANEQVTGEIRVAIKYQAIESRHLSTSDFDILRVLGVGSFGKVFQVRKKDTGRIYAMKVLDKKQVIEQKQVEHTIAERNVLIQALQSPFIVGLKFSFQTATKLYLVQDFMNGGELFFHMQNEGTFSESRARFYTAELVLALEHLHSCNVVYRDLKPENVLLSSQGHLVLVDFGLCKQNVTEDERTHTFCGTTEYLAPEIIKGTGYGKAVDWWSLGVLLYEMLFGVTPFADNRTESTHHKILHQPVVFPRSVGLPIPKGTSRYHKKLETELMSISGGNGNISHHAQDLIQKLLDKNPKTRLGSGSGPNGADAVAAIKAHPFFQGIDFARLQTRDVTPPFQPHVGITGDLDVSNFDAHFTDQRATLSMKNSTTSKLNLSSPPSTNSGTFVDGQAGSFMLQQQQRAANLYRQQQKRADNSTLNPIAGLTPGRRSNSWSSYRTLSNDSLFSIGGEPNNSNGINSSQIKSPGNVSTLQRRAFQQQQQQQQQRQQSLFQQQQRQQEFFKGFTFEGESVLEKMNRQDDGDDEEEDAVTATVGRTNVNGGGGGISGELSIGFGGHRQPNQLFSGEPESIDSIFGSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMI8</accession>
    <name>A0A9P6MMI8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BGZ80_004190</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002161">
        <property type="protein sequence ID" value="KAG0007823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMI8"/>
    <dbReference type="OrthoDB" id="1738954at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14096">
        <property type="entry name" value="STKc_RCK1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000042">
        <property type="entry name" value="Aurora kinase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000313">
        <property type="entry name" value="Serine/threonine-protein kinase srk1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030616">
        <property type="entry name" value="Aur-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24350">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE IAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="96"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="9"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="456"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="492"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="591"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="652"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="547"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="26"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="502"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="592"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="613"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="654"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="219"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="173"/>
            <end position="175"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="223"/>
            <end position="224"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="268"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="cross-link" description="Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)" evidence="8">
        <location>
            <position position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0007823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="674" mass="75526" checksum="202C709C564E071F" modified="2023-09-13" version="1">MAPFLEQFKNFIRHGKSGKDMKPRETSQQSSKPRSQANSRNTSPTRNAVDFTNSTTKQDPINANYNNTNTEAASRIVAEERQQKSKMPTYPGLERYKLIEKMGDGAFSNVYKAHDLKMDRMVAVKVVRKFELNAHQRANILKEVQIMRQLKHPGIVELYDFSESSEHYFLVLELALGGELFHRIVKLTYFSEDLTRHVIVQVAQAVRYLHEEKGVIHRDIKPENILFEPIPLIPSPPGAKPDEDDKEDEGVFQPGIGGGGIGRVKIADFGLSKVVWNEQTMTPCGTVGYTAPEIVKDERYSKSVDMWAMGCVLYTLLCGFPPFYDESIQALTEKVARGQYTFLSPWWDDISSSAKDLITHLLCVNPSERYTIDQFLAHPWIKAGETAVKAEPVVNSSVPTVEVDSSDVSPENKLLTNVVAQTPEYGAKTPYRRRAENPLSPGIGLKEVFDVSNAVHRMEEESRRRTPQTSGLHPADALNTATRQRQAFMSQLNEEDEEDYHSTYSDGSSSLTSEDESVISSLKDIQIGIGSTQIENSVKGSEDSQKAQELRMLLQQQQQEYQKVQGEIAAEKHQKYLKQQEQAGHSIPAQHTLHTGSSRSNQVGPSKSNHTISTSTSASTLASTSTTSTTRRRRAGFELNIDQATLLNRRAKQQHVTVEQQDQNINKESPAMAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMK7</accession>
    <name>A0A9P6MMK7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Flavin-binding monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_004484</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAD-binding monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002285">
        <property type="protein sequence ID" value="KAG0007584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMK7"/>
    <dbReference type="OrthoDB" id="74360at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004499">
        <property type="term" value="F:N,N-dimethylaniline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051209">
        <property type="entry name" value="FAD-bind_Monooxygenase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877:SF4">
        <property type="entry name" value="FAD_NAD(P)-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0007584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="502" mass="57906" checksum="61B88D1AE8735AED" modified="2023-09-13" version="1">MGYTKTYKDGSTPVVAIIGSGFSGLCAAIRLQTQLNLTTFQIFELEPDLGGTWWSNTYPGAACDVASINYQFSFEPNYDWSHRFAPQAEIWAYLRRVAKKHNLYEKIRFRTEVTRLEWNQDRQKWVLDYMNLATGEQGVTEADVVFSGTGPLRVPMIPKQFEDFEGPKWHTAQWNHSFDLTNKRVAVVGSGASAIQVVPSIVDKVKALEYYQRTPTYIVPRRNGAYAKLWKIMFRYIPFFHFIYFKLNYYSSEFTINIFSNKLIHRIPRSVATFLAWSYRLWQVRNKTLREKLTPKYEMGCRRVVVSSNYYPALVKKNVNVHTDSIAAIKGNTLYLKDGSSQEVDALVLATGFRVQEMVAPKFLIGKNGADLCEKWGKNPSTFYGLTSPETPNLFFLLGPYTGLGHNSVLFMIETQVDYAIKALSYMMANNVSSLEVTRKACDDFRTEFDSKMKEKVWSSACQSWYQNEDGRVTALWWGSCGEYWWKLRNFHAQNFAITKRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMY6</accession>
    <name>A0A9P6MMY6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPS7_1</name>
        <name evidence="5" type="ORF">BGZ80_003650</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001983">
        <property type="protein sequence ID" value="KAG0008255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMY6"/>
    <dbReference type="OrthoDB" id="1724687at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000554">
        <property type="entry name" value="Ribosomal_eS7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047861">
        <property type="entry name" value="Ribosomal_eS7_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11278">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11278:SF0">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN ES7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01251">
        <property type="entry name" value="Ribosomal_S7e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00948">
        <property type="entry name" value="RIBOSOMAL_S7E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0008255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="190" mass="21730" checksum="0B6FE5D8288E1F23" modified="2023-09-13" version="1">MASHKIAKNGPADEIELSVAQALVDLENNVADLKKDLKALQISSAKEVETGNGRKAIVIFVPVPQLKAFHKVQQRLTRELEKKFADRHVVFVAQRRIMSKPTRNSRAKQQRPRSRTLTSVHEKLLEDLVYPTEITGKRTRVQTDQRRIIKVFLDAKDSTSLEYKLDTFCAVYKRLTGKEVVFEFPAHHAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MN58</accession>
    <name>A0A9P6MN58_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BGZ80_004332</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002218">
        <property type="protein sequence ID" value="KAG0007711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MN58"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000245">
        <property type="term" value="P:spliceosomal complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02669">
        <property type="entry name" value="Peptidase_C19M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000068">
        <property type="entry name" value="U4/U6.U5 tri-snRNP-associated protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050185">
        <property type="entry name" value="Ub_carboxyl-term_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033809">
        <property type="entry name" value="USP39"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001607">
        <property type="entry name" value="Znf_UBP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646:SF16">
        <property type="entry name" value="U4_U6.U5 TRI-SNRNP-ASSOCIATED PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02148">
        <property type="entry name" value="zf-UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00290">
        <property type="entry name" value="ZnF_UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50271">
        <property type="entry name" value="ZF_UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="UBP-type" evidence="13">
        <location>
            <begin position="60"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="USP" evidence="12">
        <location>
            <begin position="182"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="41"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0007711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="494" mass="56245" checksum="524CF1C70D85A7C2" modified="2023-09-13" version="1" fragment="single">MDAVEESNKDNSKKNEREEDLYSDEEEAVHSVRHKRKKVNGGQSKDSAVAGTSNASSGRGSGLYLDTIQRYMLDFDFEKVCSVSLSNLNVYACLVCGKYFQGRGPSSHAYFHSLHENHHVYINLSTLKIYVLPDSYEVTDSSLDDIKYVLDPRFTPAQVAALDTNSSQSFDLNRKPYIPGFIGLNNVKANDYVNVVIQVLAHIPPIRNYFMLQNFDDKPELVKRFGTLIRKIWNPSAFKGQVSPHELLQEISNASNRKFKLTEQSDPLAFLSWFLNTLHRELGGSKKKNSSIIYSTFQGELSIESQPIESKAPKGAELAFDAKNAITKVKSPFLFLALELPPPPLFHDELEKNIIPQIPLTTVLSKYDGKTLQESVTELKRFQITRLPNYIILHIKRFSKNNFVEEKNPTIVTFPIKNLNMSEYVSDPENENALGLHYDLLANITHEGDPATPNSTSYKVHIQHRAREQWYQIQDLFVEEINAQMIFLSESYIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNC4</accession>
    <name>A0A9P6MNC4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ATP-grasp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_003495</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the D-alanine--D-alanine ligase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001928">
        <property type="protein sequence ID" value="KAG0008398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNC4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008716">
        <property type="term" value="F:D-alanine-D-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011095">
        <property type="entry name" value="Dala_Dala_lig_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048781">
        <property type="entry name" value="Sos7_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23132">
        <property type="entry name" value="D-ALANINE--D-ALANINE LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23132:SF23">
        <property type="entry name" value="D-ALANINE--D-ALANINE LIGASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07478">
        <property type="entry name" value="Dala_Dala_lig_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20882">
        <property type="entry name" value="Sos7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="6">
        <location>
            <begin position="18"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="449"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0008398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="670" mass="75139" checksum="E82FC329345775CD" modified="2023-09-13" version="1">MTDLENIIDDIGFPMIVKPSISYASINISMSSVVHTPAQLLEQINKSLSASNPDVVAPDRMELSQEKEREQKEHKNGVIGKASLNEKNMGIGIETPTVFVERFLAGREFTVLVVGDKDWGIKVFPVAERAFDPKLGKFERILAFDKYWEGYDLEGGHGKEDDEELCKYQMANEAWQDQLQEVAKNAYLALRGNGYGRVDIRTLDMDNCEPVVLEVNANCGLSFEKDSSSMANILIMSDIAPPAFVRDLVDHALHRSRVLYEFLNSDFASQQSNSNLAFNSNVDNTQGLLERLSSSLIHEATFAMDPESTARSIELCGALTSEFQHSRLYIHGLQEEFLVENKLDKLEAVSGGAALALTRLEGDLHHFDKLAISYTELATKERFLGFIAEEIPLNITLESNQKMEANAASAKKVEEETDMSVIQLQSQINETAEIACKEYDDLHQGILELTKALKDIQNMERELAEMKKMDDQYRGMTLEHSQKVLAAQTQQLYQLHQDIDEATAEIEELKWQESKLKDSNQLLDIQCIKVESQAKDAIKMSSLRRPEIENAYKECLEATRQYQEGVGLESIQYLADSNSLILEYKIVPGSAAIHTINSAGKTSSARNTRNRKPILTQFLIKVHPKSGRLLTANIENAGCDVKDVIQIAKARNDISFLVAETLDRVMKAHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNG4</accession>
    <name>A0A9P6MNG4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003463</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001919">
        <property type="protein sequence ID" value="KAG0008417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNG4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009467">
        <property type="entry name" value="Glycolipid-bd_prot_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06475">
        <property type="entry name" value="Glycolipid_bind"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159275">
        <property type="entry name" value="PA1994-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="101"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0008417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="332" mass="36965" checksum="5A850E0D8D686895" modified="2023-09-13" version="1">MLKGEILISGKQSGYIQYTIVLDNQWMTRKVKMSSMFDNQEKRLILEVDQDQRWYKVTERRAARTRSFYRSGLSQSQDSGDHGSGNNPSGDRSVSQCSMQDADASLSDASYSSSSDSECSIPFEKINLTWTPPPKGTKRASKRFSSLNPLNLKATTSSPKPDNICTSPITITNNEAQHVAQISSPTTSTTPVPKALTRTMSTSSILGPKKYEHLPHLDGCIHLDLGYDVSPSTLLFPIRRTTLGVEPEKMREFLESLSFDESMTEKSALVSFPDLELRPIQTHIAYAGPGQKDNLSIVECWRDEDEESTLVEVDGDGLGVRYENLWARIPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNU4</accession>
    <name>A0A9P6MNU4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Crinkler effector protein N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_003206</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Host cell</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001838">
        <property type="protein sequence ID" value="KAG0008650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNU4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043657">
        <property type="term" value="C:host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045379">
        <property type="entry name" value="Crinkler_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20147">
        <property type="entry name" value="Crinkler"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Crinkler effector protein N-terminal" evidence="4">
        <location>
            <begin position="4"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF20147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0008650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="444" mass="49259" checksum="2C1CEE03000B70E8" modified="2023-09-13" version="1">MDKIEIFCIVEGEDTLFSVKASRDESISTLKELIQPKRPAMKDVYASDLTLWHVSIPSTPKRIIKRRDLTDAEKANKEPENIEDPSITISEVFGTSLPKRTIHLIVDPTQAPVLTRTPSPPPAELETEAFHMRLGKIKQDFFQPGNTISDFLRMFVEGELSLPEADCCVKGLPKAWLRSSSFAQKSPRPALYLLHPTRPHQTTSTTTPPSVAALETISNFQNNDLITFFGVSGCGKTRAVVEMLAQTWGFYLNGSQPIENGLNIQAITGCLLLARLLVLEYCLSLNRCDAFTRDRWMLLQVCPGAFEPTIPDVFDSIFRALLDVYHGHIPAISFPNLKRLLQTQFHLVQRLLSSYASDSPPSKFLVVLDEAQTLSDHGKGYFMSHAESGDLRSILSPIIHGLRSISSNTQNYCVVTCGTGIGADELEVLLSSGGIGNSWEQVNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MP73</accession>
    <name>A0A9P6MP73_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_002911</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001744">
        <property type="protein sequence ID" value="KAG0008925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MP73"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0008925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="196" mass="21589" checksum="4E7C45FE898F022D" modified="2023-09-13" version="1" fragment="single">MIQSLFSSKTSHLSPEEALELVNERLELAFKEDDIAKKLKFVNSANSWLKDAENIFVSKKVKDPALTEGIVHAYHEHGRLLDDLGHHYKAKKSHSSAEKWGYAHVASRHAGSSNTLGKSDTIRRSPLPTAALSVAPSIATAMHQGSSKADVTQLNHQDHTLHSTPTKVNNDKSVPNKDGMQIQQKIFDQDVTPPIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPH2</accession>
    <name>A0A9P6MPH2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dynamin-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003449</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001911">
        <property type="protein sequence ID" value="KAG0008439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPH2"/>
    <dbReference type="OrthoDB" id="5061070at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048312">
        <property type="term" value="P:intracellular distribution of mitochondria"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000266">
        <property type="term" value="P:mitochondrial fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016559">
        <property type="term" value="P:peroxisome fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08771">
        <property type="entry name" value="DLP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022812">
        <property type="entry name" value="Dynamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001401">
        <property type="entry name" value="Dynamin_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030381">
        <property type="entry name" value="G_DYNAMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566">
        <property type="entry name" value="DYNAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566:SF21">
        <property type="entry name" value="DYNAMIN RELATED PROTEIN 1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00195">
        <property type="entry name" value="DYNAMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00053">
        <property type="entry name" value="DYNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51718">
        <property type="entry name" value="G_DYNAMIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynamin-type G" evidence="1">
        <location>
            <begin position="25"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0008439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="303" mass="34334" checksum="0198152A34EC27A1" modified="2023-09-13" version="1">MFENTEYQDIIDKINKIRSYGLNKMLTIPQIAILGDQSSGKSSVLEAITKLSFPRNIETCTKFATQVSMRRSERVEMSAHIDDEPEFNKRYHTQDAAWDIHAIISEANGILCSSVEISEKVLEINISGPTLSPLTIIDLPGYINTTVDGQDKSIVQTIHTINTRYIKDSRTIILAIVPADVDLNNIFVLGEAERYDRANERTIPIVTKPDTIEPDLLPSLVQTLLNKRKNMKLGYLVMKNSSYKDIDMSWDDAKQREDEFFRSSELWTQEYAFGTRGISFQEDSGLQFFIGFPANPSKPISLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPK4</accession>
    <name>A0A9P6MPK4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_002651</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001660">
        <property type="protein sequence ID" value="KAG0009190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPK4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031902">
        <property type="term" value="C:late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045121">
        <property type="term" value="C:membrane raft"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071986">
        <property type="term" value="C:Ragulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071230">
        <property type="term" value="P:cellular response to amino acid stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043410">
        <property type="term" value="P:positive regulation of MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032008">
        <property type="term" value="P:positive regulation of TOR signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001919">
        <property type="term" value="P:regulation of receptor recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028209">
        <property type="entry name" value="LAMTOR1/MEH1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15454">
        <property type="entry name" value="LAMTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0519">Myristate</keyword>
    <keyword evidence="4" id="KW-0564">Palmitate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="93"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="105"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0009190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="164" mass="17564" checksum="1E2832474BEBA67E" modified="2023-09-13" version="1">MVSTPFGGQSQVRELESLQKIVERTAGNLIDIPSTLQLERLQQQEAQNRLNEYVSALNTVKLPQQTIRKLCSMTSVKTSGTDMPSLDGVLETAVGTGSTGKERSTTSSGSSIKTPSVREVLAEKTVDPRTVGWMASAMGELQQATESIDVEDVGDLIVTLSPPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPN8</accession>
    <name>A0A9P6MPN8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ribosomal 40S subunit protein S18B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">RPS18_1</name>
        <name evidence="7" type="ORF">BGZ80_002595</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the universal ribosomal protein uS13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001644">
        <property type="protein sequence ID" value="KAG0009247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPN8"/>
    <dbReference type="OrthoDB" id="5534642at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.50:FF:000002">
        <property type="entry name" value="40S ribosomal protein S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.910.10:FF:000002">
        <property type="entry name" value="40S ribosomal protein S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.910.10">
        <property type="entry name" value="30s ribosomal protein s13, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01315">
        <property type="entry name" value="Ribosomal_uS13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027437">
        <property type="entry name" value="Rbsml_uS13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001892">
        <property type="entry name" value="Ribosomal_uS13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010979">
        <property type="entry name" value="Ribosomal_uS13-like_H2TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018269">
        <property type="entry name" value="Ribosomal_uS13_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003140">
        <property type="entry name" value="PRK04053.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10871">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S13/40S RIBOSOMAL PROTEIN S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10871:SF3">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00416">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002134">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46946">
        <property type="entry name" value="S13-like H2TH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00646">
        <property type="entry name" value="RIBOSOMAL_S13_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="RIBOSOMAL_S13_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="4 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0009247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="156" mass="18172" checksum="CE863737EBBF24E5" modified="2023-09-13" version="1">MESSLLVPEKGQFQHILRVLNTNVEGKNKIMFAMTNIKGVGRRYANLVCKKADIDLKKRAGELTNEELERLVTIMQNPTQYKVPQWFLNRQKNFVDGKYTQLLANGLDNQMREDLERLKKIRAHRGLRHYWGVRVRGQHTKTTGRRGRVVGVSKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPS0</accession>
    <name>A0A9P6MPS0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CipC-like antibiotic response protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_002357</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001579">
        <property type="protein sequence ID" value="KAG0009468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPS0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022234">
        <property type="entry name" value="DUF3759"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37450">
        <property type="entry name" value="CIPC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37450:SF1">
        <property type="entry name" value="CIPC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12585">
        <property type="entry name" value="DUF3759"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0009468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="96" mass="10539" checksum="B62D2C43D92A6E35" modified="2023-09-13" version="1">MFGFGQDAHDQVYGGKTHKSSWTHEILAGAAAAEAMKSVESGSTDKHKLTKEVFAGIAGAEADKLFETKGLDTLDREKVKRQAREQACQMYDQNYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQA3</accession>
    <name>A0A9P6MQA3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_001827</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001427">
        <property type="protein sequence ID" value="KAG0010053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQA3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0010053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="107" mass="12397" checksum="A438DDA2D363B952" modified="2023-09-13" version="1" fragment="single">QWRAQMVISCRTEYNGVEYKDHFQPTDRNNGGDTGQFQEAIISPFTKEQIRDYIGHIGGVTATVGNEYQLINQTGKIRLMEMELSPYDKKTFKRMTDSGFQRYGLHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQG3</accession>
    <name>A0A9P6MQG3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001394">
        <property type="protein sequence ID" value="KAG0010189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQG3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="579"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="57"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="223"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="302"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="361"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="386"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="397"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="415"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="431"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="464"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="474"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="616"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="664"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="679"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="721"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="999"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0010189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="999" mass="109468" checksum="7DB1699C5283EC0A" modified="2023-09-13" version="1" fragment="single">APPTPPLEEIRKSFEMIQGLPNIMSPTIPSWPAPARSVTGGKQPGKVPKVPSALGVSSDESSNSGSDSGDSSSDADSENISMSDADAHTRSRKHIGPKVSSNSSSTVLKAKSKAAYGMDSSDDDRDMDIDRPSRVDKEGSVDAGRYSGSDASRKDSRKQDQYPSPPSTKNTTKRGRSYSSDESDSEGNKKSKGISKDHKNKQSRDDIRSDSKKRPSENGAGSGSAPGPDAKRTSTTSSSSSKIKSEPVDDKGHRADEKKRSNNSDKPGRANESHSLSPVLDRNKDRRRRPYYSDDDDNDLEDSNKRRSSKDTKQRAQPETTESRSRLESKDKVTRDDPIPNRKRSDSKDRNSEAANPRRKSKEDDNARETKEKTAYIEKPSTVASNKERRSKEEDASISNRTSGKNESSSKSDRTTSSAAAAAPSSPNRRSSREGQKDTKSRSEKDSREDTKPRSEKDSREDTTSSGQRNSAGNKERPTKERAREEGMTGTGVLLGTMLVIVNQIVTAEIMTTIVLRRDASKMADRGTAVVNATTDLEEDEVEIGLEETEVEIGLEIGAVIAVAIVVAIVVVIETSATLANPNSGGRGDTRHDGKSQQPQQESSKASSGRRESESKSSVPTTVSSSSSARRPSQAIKEESSSPPAPTSTSSSDARGQQEIVVQKPSSSGNSNVASVKRMSFEDYQRKKGNTEKVDTPKATSDSPALAPATALPGKQPLLSKDSSNKTASADQKPSSNSTSAPKPPSETTKKAAEYYNIFRLRRSEGITLKHNADDTLKNQNNPRLGAIQYFLSAIEFIAAFHANDKYHILTNPGRPDAAVKESINSWETMRQFIYALTNQCHSNHLAGLDGVSVLMEALVYYKVYSFQSTTLRKDMIKSGQFKKSSAKGEDSAPTVTITQEMASRMLQNVEDWAHIQKRMDDCRLWLTPDIARKQFPETFRKWCIHPDQIGQGQSFDRYVPGTTIQKIHWPLGLHLHLHELMGFVESALEEFRKRNDLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQH3</accession>
    <name>A0A9P6MQH3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Arm-like repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_002163</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001525">
        <property type="protein sequence ID" value="KAG0009678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQH3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056251">
        <property type="entry name" value="Arm_rpt_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23948">
        <property type="entry name" value="ARM_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arm-like repeat" evidence="1">
        <location>
            <begin position="288"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF23948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0009678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="411" mass="44931" checksum="4B187FF9136D8037" modified="2023-09-13" version="1" fragment="single">MPRYPFSSRISDLSIEEALDLVNKRLELACQENDSAEALELSKKVKSLLSNAEHIFASKKVKDPALREGIANAYHELGKLLENLGRDGKAKRSYSKAKKWGYVRMARQHTGSLRLLGKDDTIRRLFFPRAAPSVAPSITAALSAASSITAVISVDPSVAAVLSVDPSVAALFVAPSVAAALFVAPPSAAAAIPRDNSKTDATQLNHQDHSLHATPDNANNDKPLPNKDAVQIPQKIFDQNINPPVVKYALPEVNGRFTSTPQLAYCLSLFHPSMALEGGLDQSECDWLKARVIDSDEQKRLQTMATDLVRAFVDEGLKKPGVVAEIVSLVAVLGQDDFRRLLQTFVDGLNQSVLLDVHLLEGLAQLIRNAPQGYIDADDLVKILKLLNERLKDTHKQSTRHTYQLALTISQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MR03</accession>
    <name>A0A9P6MR03_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Autophagy-related protein 18</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">ATG18_1</name>
        <name evidence="14" type="ORF">BGZ80_001942</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endosome membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Preautophagosomal structure membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the WD repeat PROPPIN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001463">
        <property type="protein sequence ID" value="KAG0009912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MR03"/>
    <dbReference type="OrthoDB" id="1667587at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034045">
        <property type="term" value="C:phagophore assembly site membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000965">
        <property type="entry name" value="Autophagy-like protein 18 Atg18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048720">
        <property type="entry name" value="PROPPIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11227">
        <property type="entry name" value="WD-REPEAT PROTEIN INTERACTING WITH PHOSPHOINOSIDES WIPI -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21032">
        <property type="entry name" value="PROPPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0072">Autophagy</keyword>
    <keyword evidence="8" id="KW-0967">Endosome</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <keyword evidence="5" id="KW-0926">Vacuole</keyword>
    <keyword evidence="6" id="KW-0853">WD repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00039247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0009912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="400" mass="43507" checksum="8CF62340F90EC0E2" modified="2023-09-13" version="1">MNVSAKGSELLFINFNQDFSCISVGTIHGFRIYNCDPFGKCYSKSDSSIGIVEMLFCTSLVAIVGAGDQPVSSPRRLQIINTKRQSTICELTFPTSILSVKLNRKRLIVVLEDQIYVYDISNMKLLHTIETSPNPNAICALSPSSENCYLAYPSPTPSPTSPFSNNGRDDSHGPSGDVLIFNALTLQVVNIVQAHKTSVSNISINYDGTMLATASDRGTVVRIWSIPNAQRLYQFRRGSQSARIHSLSFNMTSTLLCVSSDTDTVHIFKLGGSSPSNSQRNGGLLDGSLDMKAGVASVLRRQSMHFGRNLAGSVGSYLPGAITEIFEPSRDFAYLKLPSPGVQSVIALSNTTPQVMVATSDGYLYQYNIDLENGGQCVLLKQYSLLDSSEETEDSPPRPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MR50</accession>
    <name>A0A9P6MR50_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">alpha-1,2-Mannosidase</fullName>
            <ecNumber evidence="13">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">MNS1_1</name>
        <name evidence="15" type="ORF">BGZ80_001534</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>N(4)-(alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 9A1,2,3B1,2,3) + 4 H2O = N(4)-(alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + 4 beta-D-mannose</text>
            <dbReference type="Rhea" id="RHEA:56008"/>
            <dbReference type="Rhea" id="RHEA-COMP:14356"/>
            <dbReference type="Rhea" id="RHEA-COMP:14367"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28563"/>
            <dbReference type="ChEBI" id="CHEBI:59087"/>
            <dbReference type="ChEBI" id="CHEBI:139493"/>
            <dbReference type="EC" id="3.2.1.113"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>N(4)-(alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 8A1,2,3B1,3) + 3 H2O = N(4)-(alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + 3 beta-D-mannose</text>
            <dbReference type="Rhea" id="RHEA:56028"/>
            <dbReference type="Rhea" id="RHEA-COMP:14358"/>
            <dbReference type="Rhea" id="RHEA-COMP:14367"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28563"/>
            <dbReference type="ChEBI" id="CHEBI:59087"/>
            <dbReference type="ChEBI" id="CHEBI:60628"/>
            <dbReference type="EC" id="3.2.1.113"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the glycosyl hydrolase 47 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="13"/>
    <dbReference type="EMBL" id="JAAAID010001352">
        <property type="protein sequence ID" value="KAG0010380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MR50"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004571">
        <property type="term" value="F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001382">
        <property type="entry name" value="Glyco_hydro_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050749">
        <property type="entry name" value="Glycosyl_Hydrolase_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036026">
        <property type="entry name" value="Seven-hairpin_glycosidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742:SF55">
        <property type="entry name" value="ENDOPLASMIC RETICULUM MANNOSYL-OLIGOSACCHARIDE 1,2-ALPHA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01532">
        <property type="entry name" value="Glyco_hydro_47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00747">
        <property type="entry name" value="GLYHDRLASE47"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48225">
        <property type="entry name" value="Seven-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0106">Calcium</keyword>
    <keyword evidence="7 12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="13" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="211"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="733"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="792"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="14">
        <location>
            <begin position="36"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="47"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="82"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="104"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="115"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="14">
        <location>
            <begin position="128"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="146"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="161"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="174"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="748"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="823"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="846"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10">
        <location>
            <position position="326"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="458"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10">
        <location>
            <position position="590"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="629"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="717"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="525"/>
            <end position="576"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU361193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0010380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="976" mass="109370" checksum="953D5E4627A11796" modified="2023-09-13" version="1">MSSLSWTSPLSSPSNAPSRPRVALPKGQQDKKIDDMPPPPPPPPQPNNNNDANAKPASGDSASDSGANDAAAKAAAEAKKQQEKKKKKKKKAPPTLFEFEEEKEEKKEKKEKKPPNKGKPKDKKPKKQPPPPPPAPVKAPEPVKAPEPVKVAPVEPAPIKQQHDWSEDKDTSETNEINDINNSVLDESSLNVDESEDIFDVDADDSSFINDDTTTGGRLPSFDKGYKKIPHKNTPNSPLWESRKEKVKQAFVHAWSAYRRDAWGKDEYHPISKYGSNMIRKGQGFTIVDSLDTILLMGLKSEFEEAKEWVRDELDFDQDAEVNLFETSIRVLGGLLSAYDQSDKEPVFLDKAIDLADRLMGAFETPSGIPYASVHLKDSRGVPGHDRGISSTSEATSVQMEFKYLSYLTGDDKYWKAAENVMFKVKEIDNLDGLVPVFINPYTGRYHGGEIRLGSRGDSYYEYLIKQYLQTNKQEKVYKDMYDHAISGVKKHLLGRSIPHNLLFVGEISRYEPAILSTKMDHLVCFLGGTMALASTEGRPLGEGEYSGSGGPLPRSRFTKLQEEDFKIGEELTESCYEMYRQTETGLAPEIVHWVNKLEQIRGKSPLQHAPGSDFIINDRDGHNLLRPETVESLFYLWRLTGDEKYRNWGWNIFEAIEKYSKVESGGYSSIHDIRRADKIAFSDKTETFFLAETLKYLYLLFGSDDVLPLDKYVFNTEAHPFPIFTPPKEFLTRTGGISNSDSNQNNAEEEKEAVEQTEDDEERRYKEHIIKEDSLVEGVDDEAEEEMWDGGVKIEDMEDEVAGTDDSLSSSEPGDGEYSPSEPEDGEYSNPDDEVDPDIQKDEVDLGFEDPAVEDEEGELDEEVQEVEVEYEDNGTDGEQYEGEEGEEGEEGEDEEGEEGEDEEGEEGEEGEEGEEGEEGEDGEEGEEEGEEGEEGEEGEEGEEGEADEELGGEQEGEEDSQEDAESQEDERDLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRG7</accession>
    <name>A0A9P6MRG7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001691</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001391">
        <property type="protein sequence ID" value="KAG0010199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRG7"/>
    <dbReference type="OrthoDB" id="2414611at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="46"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0010199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="128" mass="14092" checksum="7BCA82673D9B5839" modified="2023-09-13" version="1">MSNTQSNKSDTPHRPGSTIHSTHACLETFDQATREQREHEIAQEKMNSAMSSTNTTNTTTSATNASSLLSNSGDPDVWHHPGSEKEANTAVQLDRDLRQSRRMSDSDRQKASGNTRSASWTTGLPYVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRL4</accession>
    <name>A0A9P6MRL4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Epoxide hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_000887</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001199">
        <property type="protein sequence ID" value="KAG0011159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRL4"/>
    <dbReference type="OrthoDB" id="1694274at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02603">
        <property type="entry name" value="HAD_sEH-N_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="entry name" value="Putative phosphatase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052898">
        <property type="entry name" value="ACAD10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47829:SF1">
        <property type="entry name" value="HAD FAMILY PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47829">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12880)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0011159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="283" mass="31147" checksum="C14A8A4312972EDE" modified="2023-09-13" version="1">MATSNKSSTQEKSFKAVFFDMGGVVVGSPFSGIAEYERDYGLPVNYLNVAISRSGSNGAFQKLERNEIDLWAFYDAFSEQLSDPLNVAAYAQYAQLRNKVFDEKSFKAPKVNGRELFHRMMGKAAVVVPSMVHAIAKLREAGYIVAALTNNFHYPTDEKGLREQDLILATAGTLNQSQSSSPKSGSLVMGQEEIKSLFNHYIESAILGLRKPDPAIYRKSCEIVGVQPSEVVFLDDIGENLKSAQNVGFTTIRVELGKPEKAIQQLETILGRGIKLLPSEAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRV5</accession>
    <name>A0A9P6MRV5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BGZ80_000847</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. COT1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JAAAID010001187">
        <property type="protein sequence ID" value="KAG0011212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRV5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007010">
        <property type="term" value="P:cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd21742">
        <property type="entry name" value="MobB_NDR_LATS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05573">
        <property type="entry name" value="STKc_ROCK_NDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000024">
        <property type="entry name" value="Probable serine/threonine-protein kinase cot-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000192">
        <property type="entry name" value="Serine/threonine-protein kinase cot-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059233">
        <property type="entry name" value="MobB_NdrA/B/Cbk1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050839">
        <property type="entry name" value="Rho-assoc_Ser/Thr_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22988:SF76">
        <property type="entry name" value="CHROMOSOME UNDETERMINED SCAFFOLD_135, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22988">
        <property type="entry name" value="MYOTONIC DYSTROPHY S/T KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="148"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="13">
        <location>
            <begin position="514"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="767"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0011212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="767" mass="88111" checksum="D2565E93F8D07361" modified="2023-09-13" version="1" fragment="single">TQLKFDLVRREDSATFATPPETLKGPSFHTKLADKESHQRDASYATFIIAENDDPEGISDGYDEIESSTVPSLSTVEQSSSTKIFFESYYHRLLTNPSSRSRRRLQLERQLESMGISETEKAAMRQEWIANETEYMRLMREKISVNSFLILKTIGHGAFGVVKLVQEKDTGLYFAMKVMRKADMLKKGQEGHVRAERDLMTAASESAVWIVKLIYSFQDADHLYLVMEYMSGGDLLNLLIEKDIFEEDFAKFYVAEMVLCIEEAHKLGYIHRDIKPDNFLFNKEGHIKLSDFGLATDFHWAHDTAYYESQRRALLRKTGIDIENADTLRSRKKPNATKTALAWNLDDDEFAQSIGRPPPNQSILTWRDRNRKKMAFSVVGTNNYMAPEVLRGTGYDRGCDWWSLGVIMFEMLYGYPPFISKSRHTTRLKIINWRQTLRFPAKPKVSREVQDLIEKLICEKEFRLGRSPPANNANKRWSTVSPHLMQQQQQQLNQSVNSQGLGDASEIKNHPWFQGIDWANLRSQQPPFKPALKDPADTRYFDEMVDDNPMAAPEGEERVIRDPLLGNKNEGRRLLDMRKKLAFAGYTFRGFHAPGGKKSKETDPLQGFKIHPNAWGMGATDSVRLRSMSFSPLEPSATKTEGVISARIWDTLKEEISGELEDKENSQSNIQMNIKKLEAISKATKRKQAYSPYLWISQLPSAVMPDDIKRMEISEGSITDIIYHRNQYMEFLNRVTVVFRSATDAVEFITQNYRKYLGGHKLVMNMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSC1</accession>
    <name>A0A9P6MSC1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ricin B lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_000942</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001208">
        <property type="protein sequence ID" value="KAG0011101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSC1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040129920" description="Ricin B lectin domain-containing protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0011101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="161" mass="17751" checksum="3E718090ADBC0D38" modified="2023-09-13" version="1">MAASTRLLALALLVVLALKAVVAQGPPSGKYMLLSEAIPPIFVGSHNEGYNSPVILGGENNVWTIERMNDGIYIFTLQQAGKPFHARSVGDHLFMSPVPVSPSVEWRVQNRDGDTYSIVASSSIPPMAWTTRAFGSDPWVVLEEFNPSEPGQRWKFIQRQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSC6</accession>
    <name>A0A9P6MSC6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Crinkler effector protein N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_000948</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Host cell</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001209">
        <property type="protein sequence ID" value="KAG0011095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSC6"/>
    <dbReference type="OrthoDB" id="10480210at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043657">
        <property type="term" value="C:host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045379">
        <property type="entry name" value="Crinkler_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20147">
        <property type="entry name" value="Crinkler"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Crinkler effector protein N-terminal" evidence="4">
        <location>
            <begin position="10"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF20147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0011095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="187" mass="21755" checksum="47D405A442D82291" modified="2023-09-13" version="1">MGKTSVRKEEDLTAAIKEQKKPLLDNVHLDDIKLWKVSRITDNDEVININILKKELLNPKKHLSFSPSENPTLGAPGTTIQIVVESPVSPRLKIFAHFKFDDYFAKRYGISRREDILPFETLGRVSIESDERYVRESGHIANWMDMMHEVMGSKNKIGKASYLSYYATSTIRFFRQFVRLVRMAYNW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MT89</accession>
    <name>A0A9P6MT89_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">60S ribosomal protein L36</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_011681</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL36 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000970">
        <property type="protein sequence ID" value="KAG0012526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MT89"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.1760:FF:000001">
        <property type="entry name" value="60S ribosomal protein L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1760">
        <property type="entry name" value="60S ribosomal protein L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000509">
        <property type="entry name" value="Ribosomal_eL36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038097">
        <property type="entry name" value="Ribosomal_eL36_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10114">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01158">
        <property type="entry name" value="Ribosomal_L36e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01190">
        <property type="entry name" value="RIBOSOMAL_L36E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0012526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="71" mass="8152" checksum="D5591D6E59581399" modified="2023-09-13" version="1" fragment="single">MAVTQRTGIRFGQNRGHITTVRELKTPMSYKKGVAGKRVTFVRSIIREVAGFAPYERRIMELIKNSKDKRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTD7</accession>
    <name>A0A9P6MTD7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_011517</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000935">
        <property type="protein sequence ID" value="KAG0012779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTD7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="282"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="328"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="494"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="282"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="337"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="355"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="380"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="500"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="526"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0012779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="574" mass="63400" checksum="3A41F80466B9E4A8" modified="2023-09-13" version="1">MDNNNLDSVDRDGNTRAIASETAPSPLIGPDNNITCNHEPMNNRHEGITPTTATVVVETNTSLSAPIPNTISTAPNTDPNAVHSSDEIADTTANTILASKKTAQVLQEQISVITTSSSSPNLPPSAVPSTEAASNYPSPSPSSPSSPLLTVPAEEVIPTSTVVTDHKDEGESITANSSSPIKSCQTPVLIDAENDQDLDNASNEMEKDVPSRTNTPLSIETTGLTAQGSFLKTSQSLPRATVEDVPFLNARTPADSDAFLSSTSSTSSSSSLSEYLIIGQEQVEKEDSEYDRRSDHSSDFYGEQYGSFAAGEYSDASLDSQGEDVHFNPQQQEQHHHSQSRRRRNRHRTSFVEGSDNELYEFPEGYQDEDEHGPHSSQHRITETDTYESHRKKRDSVLSQAEASAPLLSLPTLKAPSIRGISKSVIEFVVVSAVCVTLMTCLFAFSYVSTGANHLLGWYSDQQIGQRIRDGIKEREHMVQEALEKMAGEEYAKVKRRSRQYQQQHQQTYGYGHGNPYQQKYQQQYRQEREQRQQQRQEKEGLSTAEWQDLIRAASISFMARFSKPTPPVRGARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTZ4</accession>
    <name>A0A9P6MTZ4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Protein ARV</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">ARV1</name>
        <name evidence="15" type="ORF">BGZ80_011528</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes.</text>
    </comment>
    <comment type="function">
        <text evidence="12">Regulates also the sphingolipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Endoplasmic reticulum membrane</location>
            <topology evidence="1 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="12">Golgi apparatus membrane</location>
            <topology evidence="12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the ARV1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000938">
        <property type="protein sequence ID" value="KAG0012756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032541">
        <property type="term" value="C:cortical endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032366">
        <property type="term" value="P:intracellular sterol transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097036">
        <property type="term" value="P:regulation of plasma membrane sterol distribution"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006665">
        <property type="term" value="P:sphingolipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016125">
        <property type="term" value="P:sterol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007290">
        <property type="entry name" value="Arv1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055414">
        <property type="entry name" value="LRR_R13L4/SHOC2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019487">
        <property type="entry name" value="RAM_signalling_pathway_SOG2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14467">
        <property type="entry name" value="ARV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14467:SF0">
        <property type="entry name" value="PROTEIN ARV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04161">
        <property type="entry name" value="Arv1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23598">
        <property type="entry name" value="LRR_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10428">
        <property type="entry name" value="SOG2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52075">
        <property type="entry name" value="Outer arm dynein light chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="12" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="4" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="10 12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9 12" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="12" id="KW-0746">Sphingolipid metabolism</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1304"/>
            <end position="1329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1341"/>
            <end position="1364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1370"/>
            <end position="1390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1397"/>
            <end position="1420"/>
        </location>
    </feature>
    <feature type="domain" description="Disease resistance R13L4/SHOC-2-like LRR" evidence="14">
        <location>
            <begin position="92"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="212"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="513"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="601"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="697"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1001"/>
            <end position="1062"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1094"/>
            <end position="1126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="13">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="212"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="248"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="548"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="616"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="657"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="706"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="761"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="1001"/>
            <end position="1012"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="1019"/>
            <end position="1029"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="1030"/>
            <end position="1042"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="1044"/>
            <end position="1062"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="1101"/>
            <end position="1126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU368065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF23598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0012756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1430" mass="156138" checksum="159D41533E7B9863" modified="2023-09-13" version="1">MSQGEDGGAGSGAINGGSHGGERRINANGRGSSDLMRLIRERQDAAGSTQALDLSYANLDTLPAEIEFLRDVLEKLTMSHNSIRTLPLQLNMFTSLRYLNIRANSIKVFPAVLCHLASLEILDMSRNKITRFPDVFGNLMNLKVLSISRNRIETIPTYIGEMSQLQFLKLEQNPIVFPPPEIWEFPGQDMESWLNQLKASSDDARAISRQENNNILQQRSNRSASLDSLATPSNRRQSKGEAGLRLSFPNTIERSGQHPSNLSPDPMSHKITRTNSHHGEDQYRFISHSRGVSGDSTSSFTSTISNDCDRYSEIYFQRLAAYPPLQHPLPGERIRLIEAARGILFALSQIYRAVKQVVNCSSDENFSLMFTRLLQSANSTMAQLIQSLDRFDSSAQLQVPEQPICSEIMRCCESNVAAFRKLVHMVQAQIRTISMVADARLVRNLILMLHGALSEIRVAWESLLPLLQGTGEVSIEVGEPGHHPIKEQHLHQQAIMINNVGQSQHHLQNQHHISNNVSGNHQPHPIQLSPAMPSSSWFPAQIPHRSQNMSRTSNHSSQSTSNLHHEEEEDAQLLLTVERAIEAARRLIQCLTETCMTRVESLSSSPQHIPLHRTRSISASPPRSGGSSSGSSSSNANGKGSSQDGHTIPMSPLQLAADTSSSTAPSMANGNANHVNGVISKSDNELIRSPLFSPVSDTVPYSNGQSPTPSSEAATTSATGQGDDATSKHERRPGTHSKGSSKTSFDPALPSIPQDEANEISSQTPPTSTSASVAAASNTTAVTATGTLSAVSTPQYQPIMTARSASISGLPSSSYHTISSSGPPHMAASSLPSQGFMSSGSFHTHLPLGYGQPSTPGLYSSGSTSFPFPSGGVAAMPASQLWREMKDCLLQMTEIVKRLDLDLTMIKTDDQSYHPHFQQHSHQYQYGQFQPHSQILHQGHTLHPHQQHHGSSSYQQHSNDEAAILRRRFGMGVSDFVKSVIVISTLVRHLSTSSTNPASKIAAATTAQAPSSSSPPPSTNAFSTSPSAPRTRSGSAADNPSHSTPPVTNVNPTLTSSASATDISSSSYSTVTAVSAATPPSTYTSASSLSAGATSAVSPEKATQLQSQGHRQNQNQLAKHSQQQQPEVFSRLVTNNVSILTKITKELTVRMPRSSFRDYLLSSSSVPTSSSSAGGGIGMGIMGIGNNNPSAFGVGPAAVSSLYTEYSKGNIRLTYCEHCKKLADKYVEHDFVIIFVDMMLHKKPVYRHLLFNRLPYRDTGIDPNVFKLGVLLILFDVYIKWFRLEQEATVIDVSFSQHALVFQYLYILFLCIIEFLSFHFGVRLIVSLWYGGRYAILKYNYITTTLIISSFAKMLLILMVIWDYTELEHSWHLVNFIVLTSNIEALSVFLDTGYLSTTLVIFFGLACRVLMQIAFAYITGDSVLVTVASM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MU25</accession>
    <name>A0A9P6MU25_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_011529</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000938">
        <property type="protein sequence ID" value="KAG0012757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MU25"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.10.10:FF:000031">
        <property type="entry name" value="Calcofluor white hypersensitive protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057315">
        <property type="entry name" value="Exo_endo_phos_PGAP2IP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051916">
        <property type="entry name" value="GPI-anchor_lipid_remodeler"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053912">
        <property type="entry name" value="PGAP2IP_TM_1nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053911">
        <property type="entry name" value="PGAP2IP_TM_2nd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14859">
        <property type="entry name" value="CALCOFLUOR WHITE HYPERSENSITIVE PROTEIN PRECURSOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14859:SF1">
        <property type="entry name" value="PGAP2-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23022">
        <property type="entry name" value="6TM_1st_PGAP2IP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23021">
        <property type="entry name" value="6TM_2nd_PGAP2IP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23226">
        <property type="entry name" value="Exo_endo_phos_PGAP2IP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="206"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="231"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="256"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="286"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="PGAP2IP first transmembrane" evidence="3">
        <location>
            <begin position="1"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="PGAP2IP second transmembrane" evidence="2">
        <location>
            <begin position="165"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="domain" description="PGAP2IP C-terminal nuclease-like" evidence="4">
        <location>
            <begin position="393"/>
            <end position="625"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF23226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0012757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="676" mass="75849" checksum="86D120EA6A5A4AA0" modified="2023-09-13" version="1">MIWYFPLWNMGLSGYELFLFCNMAAGLLGFSGLRKNLERYKGQAHLASLIGVYSYRIFDPAYRLMAVATGVTISLLTWGTVLFGQRHQNGRAERGVMALALGLILHNVVKQAWWANNPIWPIMNSSNGGRNMLGLILGILASVQIILRKEPYELEPKSGENSKKGESWVKASIGGGAYLFCLHSMYTEASTISRWSLGGYPNTGPHAVTGGLMVIVAMAAGLVLSSRRDFVTSLAWFGIGSAGLALLHFVEGDVGFFGGIVFTVFALSLFPTIFRSLARQPPGRAFLVAMTTYNILALAHVWVVAYAFVPGGEIMREHTDYVILAMQGCLLAGIRNAHSTSWPLISETRKRSVFSIIRLYTKLTLAGLILSSIFVSLQRIPRTPPKPYHPEHKLITAGIWTIHFAIDNDMYNSEMRMRDAIRDLELDVVGLLESDLQRMIMGNRDLTQFLAEDLNMYADYGPGPTKHTWGCTMLSKFPIKQSTHHLLPSPKGELACAIHATLDVYGKDVDVIVSHNGQEEDLRDRQLQTTELGRIMRESNNPFLFLGYVVTKPGKGEEIYELLMDSGRMHDIEVSDWDRWCEYLAFRGVKRVGYARVSHGGITDTEIQVGKYQVLEDSLPSGEHRRIPLEEFKKQASYEQIPEDQVPQGLRYPSMFYGAGVRNHHFHVFDRPYYYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUZ8</accession>
    <name>A0A9P6MUZ8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">60S ribosomal protein L17</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPL17_2</name>
        <name evidence="5" type="ORF">BGZ80_010890</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000809">
        <property type="protein sequence ID" value="KAG0013725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUZ8"/>
    <dbReference type="OrthoDB" id="10254664at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00336">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.470.10:FF:000010">
        <property type="entry name" value="60S ribosomal protein L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.10">
        <property type="entry name" value="Ribosomal protein L22/L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001063">
        <property type="entry name" value="Ribosomal_uL22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018260">
        <property type="entry name" value="Ribosomal_uL22_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005721">
        <property type="entry name" value="Ribosomal_uL22_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036394">
        <property type="entry name" value="Ribosomal_uL22_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01038">
        <property type="entry name" value="uL22_arch_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11593">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11593:SF10">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00237">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54843">
        <property type="entry name" value="Ribosomal protein L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00464">
        <property type="entry name" value="RIBOSOMAL_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0013725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="180" mass="20215" checksum="F176C2D57DC56A54" modified="2023-09-13" version="1">MVRYAATPANSSKTALSRGSYLRVHFKNTREVAAAISGMKLKKALTYLEAVKDHKQAIPFRRFNGGIGRTAQAKPFGVTTARWPVKSVEFVTDLLKNAESNADVKGLDQDALVIKHIQVNQAPRQRRRTYRAHGRINPYMSSPCHIEIILAEENEAVKREVEAKKPKLNVRQLAARARRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MV05</accession>
    <name>A0A9P6MV05_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_011073</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000845">
        <property type="protein sequence ID" value="KAG0013447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MV05"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3450.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038060">
        <property type="entry name" value="C12orf66-like_central_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018544">
        <property type="entry name" value="KICS_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09404">
        <property type="entry name" value="C12orf66_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158548">
        <property type="entry name" value="FLJ32549 domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="92"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0013447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="321" mass="35997" checksum="79552606B30DD62E" modified="2023-09-13" version="1" fragment="single">HLYHMYSDLIADTERELAVYRDASIGTFGSTSVDHSRTTGTIGIRQGASGHNSPIMNTPEAGQFSIHQHMSTVSGSNNINNGNANARIADNIPNSSPSPSYSHIQNSSSFNEQEGQSAADHIVLYTIIRELCSIRMMLTGIYRLISLSTVEIDVDDIIPDIEHAQRHYESEAVEIQSSVLGAGIECEIRSLKHGLLLHKAISEYDIQKSSINLHLARVALSEWHHISSEQDYADKSYNRPEETSWRYNFFSSGEDKSKSSLAAKGKFNLQPNHLLWLNRWIASEKSKMTIYFMETLLEKEKAMGGDERSLWVNTEPDLHGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVN6</accession>
    <name>A0A9P6MVN6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_009817</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000621">
        <property type="protein sequence ID" value="KAG0015513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVN6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031380">
        <property type="term" value="C:nuclear RNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031048">
        <property type="term" value="P:regulatory ncRNA-mediated heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001366">
        <property type="entry name" value="ATP binding protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057373">
        <property type="entry name" value="ZNFX1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF341">
        <property type="entry name" value="NFX1-TYPE ZINC FINGER-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25396">
        <property type="entry name" value="ZNFX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ZNFX1" evidence="4">
        <location>
            <begin position="114"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="2">
        <location>
            <begin position="314"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase-like C-terminal" evidence="3">
        <location>
            <begin position="700"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0015513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="977" mass="112761" checksum="ACAA6567CBF045D4" modified="2023-09-13" version="1">MDSGPRKGQHAKQEGRFIQQPEIDPYKGLKKPQPLLDESWKNDLPRDNFRFQSICPTIMDIEEEDFPDPPENIVHKAYDSTEQYLETHFRLLRADCIIPVRSAIRLYRVGAVDDNDLMVYVNVRPVELLFATFGVVHRMSFLVDGRRVNWKQSKRLIPGTIVCLSVDHFENYRFATIIERDLEYLQNPRDLRIGLKFLSPDPRFDFDSDVRYTMIEAMQGYYEAYQHVLKCLQDIDPDTLPFRPQLVGLEPTLEHPEYSQHVQAVQDIDYIEDSVLAFPDILKDAENSIPSRRREREEMEPRLRDKRAQPNVLEAMDRMLTKDFAIVQGPPGTGKTFLGLLTTHILLENTRTSATGPIIVVCQTNHALDQFLEGIMKFEDRVIRLGSRSKSPIVSEKTLFNIKQRYKNNPDEARNDGIRGGVPRKFFLMKDKLESDMLSLLEELSVEYVPLSKFLDMKIISKDQFDSFANDGWVSRFNQEEEPTAEPWLQAVPQFHDPNNVSYFDDATLKDDFVTEIDEEEVQDRIEDFMTVNIEETKISGQSVGFKQSIVCHVDDFVVGDVGPFLNMPNVYDIPPQKRLGVYKRWLQRYKSSLITRLGELHTTYNLVCENIRAEFRRSDVRILDTARIIGMTTTAASKYHDLLCRLKPKIMICEEASETMEAHLMCALTPTIQHLILIGDHEQLRPNMSVDELKHKNIDVSMFERLVKNQFPFSVLDCQRRMRPEIRSLIKPIYRNLLDHESVYRYENVRGMVDNVWFWTHDEPDRLGTNNSHYNPHEVGIATRLAAYLLQQGYEPSQITILAMYSGQRNKIQEKLRQCHVQGADRIRVSTVDGFQGEENEIIILSLVRSNDTNSIGFLKTSNRVCVGLSRAKKGMYILGNAKLLMDQSNLWRVIISSLFDRDPSLFKIGNRIKLQCVRHPEMISEVGLESDFDQAITRTWIAAIHVEGHLIAASTFALQTVVILVGLARLVDPEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVW0</accession>
    <name>A0A9P6MVW0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Tubulin alpha chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">TUBA3D_2</name>
        <name evidence="18" type="ORF">BGZ80_009846</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4 14">Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the tubulin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000627">
        <property type="protein sequence ID" value="KAG0015459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVW0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005200">
        <property type="term" value="F:structural constituent of cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02186">
        <property type="entry name" value="alpha_tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.600:FF:000005">
        <property type="entry name" value="Tubulin alpha chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.20:FF:000001">
        <property type="entry name" value="Tubulin alpha chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1440:FF:000008">
        <property type="entry name" value="Tubulin alpha chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.600">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="entry name" value="Tubulin/FtsZ, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="entry name" value="Tubulin/FtsZ, GTPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002452">
        <property type="entry name" value="Alpha_tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013838">
        <property type="entry name" value="Beta-tubulin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000217">
        <property type="entry name" value="Tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023123">
        <property type="entry name" value="Tubulin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017975">
        <property type="entry name" value="Tubulin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11588">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03953">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01162">
        <property type="entry name" value="ALPHATUBULIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01161">
        <property type="entry name" value="TUBULIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="Tubulin C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="Tubulin nucleotide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00227">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00228">
        <property type="entry name" value="TUBULIN_B_AUTOREG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="11 14" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 14" id="KW-0493">Microtubule</keyword>
    <keyword evidence="8 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin/FtsZ GTPase" evidence="16">
        <location>
            <begin position="47"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin/FtsZ 2-layer sandwich" evidence="17">
        <location>
            <begin position="246"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="416"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00049117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAG0015459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="444" mass="49101" checksum="DA721999F3BB2C13" modified="2023-09-13" version="1">MREIVSIHIGQAGIQIGNACWELYCLEHGISPDGTLGANVSIPGSTPATFFAETGSGKYVPRTVIVDLEETVVDEVRTGRYKDLFHPESLISHREDASNNYARGHYTIGKELIDPVMERIRKVTDNCNGLQGFFIFHSFGGGTGSGLGALLLERIGMDYGKKCKLDFAVYPAPKVATSVVEPYNSVLTTHATMDQADCTFMVDNEAIYDICRDKLGVERPNYSNLNRVIAQVVSSVTLSLRFAGSLNVDMNEFQTNLVPFPRIHFPLISYAPILSKGKAMHEQSSVSEITMACFDRSNQMVNCEPRLGKYMACCLLYRGDVIPKEATAAIAHAKSKSSIQFVDWCPTGFKVGINAQRASVVPDSEVAASNRSVCMLSNTTSISSAWTRLDEKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYQEVSADNTEENDEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWM4</accession>
    <name>A0A9P6MWM4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_009822</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000622">
        <property type="protein sequence ID" value="KAG0015502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWM4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093:SF18">
        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="295"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="639"/>
            <end position="1006"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="383"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="424"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="495"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="637"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="393"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="425"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="501"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="535"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="650"/>
            <end position="660"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0015502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1020" mass="110619" checksum="C4963475A9C67A4D" modified="2023-09-13" version="1">MLSTGPNAQKFLTSIPLQSQGKMMAFVSNSTTGTPQGDLLVLDTNFWIWSIPSSPNSAVTPQSRLGAAVGLSGNTVFIHGGAEVLNSDGRASSTALNDLTKLDDSTFEWTSIANGPSLMYHTMCKVPGLNLMIVFGGSDSSNTAFNSVHTFDLGQETWVLNRPVDAGNGGSVPSARKGHTSVCLNNTMVVYGGGTDRPLDDDVWVLDASASQWVWNRITTNKQLGPGARTGHSALLNGTNMLVWGGYGAPQANDTNIYILDTVAWQWSSSKELGNDTPISVPSTPSGSGKSNMPVTIGVVCGCLAIIAVFIGFVVVKRRVSRKDQNKVMRSQDNHSYLSDAERHLSGDIDLDDKPHYYHQYSGRDSGSSLGGWPAIAARRSIPAPSQGYPMRSMTTLSQQATTEIGSASERNIKAADVNGDVDTTGVQQAQSPKQTPQRDVDQTSQKTRPRGGSFTSDPYYPAHLAENDEEDADRWTFASSLSFDQREKAGSLPTLRYFPSRSTGTMGPQRSMVHSTGSLTPSYSVSRGARKDTSSSSILSGQGSMPSSPSIAAFATASSGSQQLNRDCSISPRDTALFNAVSPLDRVSLMCSGLEAESQVPGDDDGLSAKYLSPKSRFPQWRDTYRGESFIEATVDEEEEETHVGHNRTGSVSTTDSSATTVTLDHPALLTLVQSLPARYVVSKSPSPMHGTENDILFAVDSDTQQPIVIKSFTRKEAWERECRTLRRLRGPCVVELKHVATLVLSESGEQNKPSTVRLTILERLDETLAQMLKNARKAKKVALREQVASSNSISEAKSLDLSGAGLYRSGPALDERYVKDIVKGVLRCLTWCHAKKIVYCDLKPTNIMRNRDDSRQQWKLIDMESSRTAGEERTSVGTVGYCPPEVAMGASLSTTTDSTSTGVTAQYSMDLWAFGCLLYELFATRPLIPLSATEDEVLHFLANPSPDTPALPNGLRWTNSRELEIPYFELAVPDNSARQLIRMLLNPDPNSRATMDQVLNSEYLSGNPEERTSSTSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MX74</accession>
    <name>A0A9P6MX74_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF1748-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008488</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000461">
        <property type="protein sequence ID" value="KAG0017248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MX74"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013726">
        <property type="entry name" value="Mitofissin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28075">
        <property type="entry name" value="CHROMOSOME 16, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28075:SF1">
        <property type="entry name" value="DUF1748-DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08520">
        <property type="entry name" value="Mitofissin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040378873" description="DUF1748-domain-containing protein" evidence="1">
        <location>
            <begin position="28"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0017248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="72" mass="8143" checksum="EAE697F9940B378C" modified="2023-09-13" version="1">MLGKLFHYAFDAILLSAVLAGIKRSTGLTVARNKIEGKDARSAVDKYLDIGEWVMDQGIIFMSTSKYFERKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXB2</accession>
    <name>A0A9P6MXB2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Elongation factor 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">EFT1_3</name>
        <name evidence="10" type="ORF">BGZ80_008643</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000475">
        <property type="protein sequence ID" value="KAG0017073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXB2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01681">
        <property type="entry name" value="aeEF2_snRNP_like_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04096">
        <property type="entry name" value="eEF2_snRNP_like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16261">
        <property type="entry name" value="EF2_snRNP_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000010">
        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000006">
        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.240:FF:000003">
        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.870:FF:000002">
        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000058">
        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.870">
        <property type="entry name" value="Elongation Factor G (Translational Gtpase), domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005517">
        <property type="entry name" value="Transl_elong_EFG/EF2_IV"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908:SF10">
        <property type="entry name" value="EUKARYOTIC TRANSLATION ELONGATION FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908">
        <property type="entry name" value="TRANSLATION ELONGATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03764">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00889">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 10" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="9">
        <location>
            <begin position="5"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0017073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="830" mass="92169" checksum="F6795DB6B3CA1B65" modified="2023-09-13" version="1">MHNASNIRNVTAISSINHGKTTLSNSLVSMAGITSTAHHSEASPMEIHQDEQDRGITIKSTTTPLLFKMTEDDITAIKQSTNGNNFLINLIDSPGHVDFSSEVITALRVTDGALLVIDYVEGVCAQTETILHQALSERIKPVLVINKVDRALFELQVTNEDIYQSFNRTIESVNVIVTTYHDQTLGDIQVSPDHGTVAFASGLQGWAFTICQFAMRYARKFGVNYQIMMSKLWGENYFNPATKKWTTKNTDSNGNRLERAFNMFILGVITKLFDAVMNAEKEDIVKILEKLEITLTSEQMDFKGKRLLETVMKKFLPAGEALMEMIIIHLPSPVTAQKYRVETLYEGPMDDECAVGIRDCNPNGPLMLYVSKMVPTSDKGRFYAFGRVFSGTVRSGLKVRIQGPNYQPGRMTDLFLKSVRNIVFMMGPHLEHIEDCPAGNIVGLVGVDQFLLRTGTVTTSDIAHNLKVIKFSSTPIVRIAVECKNAADLPNLIEGLKRLSKSDPCVVCYVSDTGEHIVTGTGELHLDTCMKELEVDHAQVPIRKSSPFVQYMETITTESSVTALAKSPNRHNRIFMRAAPLGEGLVEAIESGKVGVNGEFKARARTLADEFGWDNIEARKIWSFGPDGSGPNVLVDMTKGVAYLNEIKDSCVTAFQWATSEGVLAEERMRGCRFNIMDVVLTGDAIHRGGGQLIPTCRRAIFGSFLTATPALIEPIYLAEITCPGSAMGGVYNILNRRRGLLIREEQRPGTPIFNVRAYLPVAESFGFASDLRLSTQGQAFFQFVFDHWETMVGSPLDEGSNVRELVLRIRQRKGHNVDIPKLERYIDKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXF8</accession>
    <name>A0A9P6MXF8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosomal protein L15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RPL15</name>
        <name evidence="6" type="ORF">BGZ80_009171</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000527">
        <property type="protein sequence ID" value="KAG0016513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXF8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1120.10:FF:000001">
        <property type="entry name" value="Ribosomal protein L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1120.10">
        <property type="entry name" value="Ribosomal protein l15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024794">
        <property type="entry name" value="Rbsml_eL15_core_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000439">
        <property type="entry name" value="Ribosomal_eL15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020925">
        <property type="entry name" value="Ribosomal_eL15_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_uL23/eL15/eS24_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003269">
        <property type="entry name" value="PRK04243.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11847:SF4">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11847">
        <property type="entry name" value="RIBOSOMAL PROTEIN L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00827">
        <property type="entry name" value="Ribosomal_L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01384">
        <property type="entry name" value="Ribosomal_L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="Ribosomal proteins S24e, L23 and L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01194">
        <property type="entry name" value="RIBOSOMAL_L15E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="169"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0016513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="204" mass="23863" checksum="22CFD4DB7D563A62" modified="2023-09-13" version="1">MGAYKYLEELAKKKQSDVMRFLLRVRCWEYRQLNVIHRASRPSRPDKARRLGYKAKQGYVVYRIRVRRGGRKKPVAKGATFGKPGGHGVNQLKYQRSLQATAEERVGRKCGNLRVLNSYWVNQDSTYKYFEVILVDPSHKAIRRDARINWIVNPVHKRREARGLTSATKKNRGHGKGHGFNKTIGSGRRANWKRRNTLSLRRYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXX0</accession>
    <name>A0A9P6MXX0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">glutathione transferase</fullName>
            <ecNumber evidence="1">2.5.1.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_008452</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>RX + glutathione = an S-substituted glutathione + a halide anion + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16437"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16042"/>
            <dbReference type="ChEBI" id="CHEBI:17792"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:90779"/>
            <dbReference type="EC" id="2.5.1.18"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.18" evidence="1"/>
    <dbReference type="EMBL" id="JAAAID010000459">
        <property type="protein sequence ID" value="KAG0017266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXX0"/>
    <dbReference type="OrthoDB" id="414243at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050213">
        <property type="entry name" value="GST_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571:SF224">
        <property type="entry name" value="HEMATOPOIETIC PROSTAGLANDIN D SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14497">
        <property type="entry name" value="GST_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="4">
        <location>
            <begin position="24"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="5">
        <location>
            <begin position="105"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00047960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0017266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="246" mass="27817" checksum="890CC33D6F520FE0" modified="2023-09-13" version="1">MASLPTPTQASTEVLSQATKSNDSTFKILYFGLHGLAELTRTILAYAGAKTEELTVDWPNQKDQTPFKCLPVVYEVTSDGTVLELAESQAIERYLATKFHLFGKNEYEHHKVEQFLTSTDTTLQAFSTKVIRADADKRVEEANKFYTEVLPKFIEVHEAHLKKNGSNGHYVGDSTTLADIKTTLLINRVLFLRPKGANEVPFSAEKTPLLWKARETVDSHPTLAAWKKSQRYQELDASTKTMFKWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXY7</accession>
    <name>A0A9P6MXY7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007954</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000418">
        <property type="protein sequence ID" value="KAG0017758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXY7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="64"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="120"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0017758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="190" mass="21777" checksum="B715795421DB42EE" modified="2023-09-13" version="1">MVNVEKILSGGDDEDEDEAESDSNDDHEGDTIEADLDRNHMGVNLDEDDVLTGDDERDLDEDYLQQQQNQLQQVQQQLNSDTPQRTEGSLMDRLLELGQRHAQTPSRPNRTSNDQPPPRLTRQPQLLHQMQQRRTANSIPGFGMDYPTPSRSNIPSTTPSRPNSLYPNMSHPQREREYDEYEDGGDEMEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MY61</accession>
    <name>A0A9P6MY61_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">DUF221-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_007389</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CSC1 (TC 1.A.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000377">
        <property type="protein sequence ID" value="KAG0018266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MY61"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005227">
        <property type="term" value="F:calcium-activated cation channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045122">
        <property type="entry name" value="Csc1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003864">
        <property type="entry name" value="CSC1/OSCA1-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027815">
        <property type="entry name" value="CSC1/OSCA1-like_cyt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032880">
        <property type="entry name" value="CSC1/OSCA1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018:SF139">
        <property type="entry name" value="PHOSPHATE METABOLISM PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018">
        <property type="entry name" value="PROBABLE MEMBRANE PROTEIN DUF221-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14703">
        <property type="entry name" value="PHM7_cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02714">
        <property type="entry name" value="RSN1_7TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13967">
        <property type="entry name" value="RSN1_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="126"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="353"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="398"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="446"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="481"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="562"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="607"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="635"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like N-terminal transmembrane" evidence="9">
        <location>
            <begin position="15"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like cytosolic" evidence="10">
        <location>
            <begin position="173"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like 7TM region" evidence="8">
        <location>
            <begin position="353"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="737"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF14703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0018266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="737" mass="82772" checksum="12EB166CBDBDD800" modified="2023-09-13" version="1" fragment="single">MSDNNQNIDPSTRTFTSALAFNAAVAAAIFIAFCIVRNWNKKVYQPRTYLVKEDWITASFSIPDNVLVDRIGLDAYMFLRFNRMSAVLFFGFTLLGVPILIPLNVANGGNQVGLNAMTIANVVSSWRLWFHLALTVIFSGATVFMLWREMLEYTRRRHAYLLSAEHAKTPQSTTILVTAIPDGLHSEEILFDIFNRFPGGVRSIWLNRDPKVLIDLCQERDEVALKLEAAEYSYIRSAYVVSKKGTTVQDPKRPIGRTSKIPFVGPKVDLIEFYSKRLEELNKDIEEIRQKETVSSLNSAFIRFHTQFGAHSAVQTVVHPTPFRMAPMFAEISPLDVVWDNMNLNTISRKVRYLISTTLATGLALTWSIPVATVSSIANLASIINITHFEFLNNLPDWIVPVIQGILPPLFMGILMALLPIILFLLSKFEGHVRYSSISIAVMSKYYVFLVVNVLLISTFAGGIFKTIADVKGQGFQPIQIMTMIANSLPPVSTFFVTYAMLQGFSGPVMELLQATPLVLNYVFTILLARSPREVWNVQGRLGNVEYGIIFPPQTLMFAVGMLYSTLAPLVLPFVSFYFALFYFVYRHNFLYIYKQPFETGGLTFPLAIKQAYTGLFIFQVTIICFFVIRADASLLPHIIIMLITLIATILSYTNLNEAFNPLVTFLPVALFSKELQINRDGVVSDGSEIARIHDNETGLGDKRLTTMDSLPTKDHSSEKASLAVMGAKQEYDETGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYU0</accession>
    <name>A0A9P6MYU0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008295</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000445">
        <property type="protein sequence ID" value="KAG0017425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYU0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0017425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="254" mass="28844" checksum="76DA9B47322233FC" modified="2023-09-13" version="1">MSGDSDLFIYQYVTVVWRPACYGGFLEYQKSAVLSALGFKSAERLTALGVVSSNDYDHSVYGLGCETNYKTVKDINAKGSDEGSVTFDTSINVFVHLKQTPIAPGHHDEPDAASLEMRLKDIKERFKDACGKFAEQNRAQLASRQATRRHRPSQKFNRYRTIDRPPPKKSKDSITEPLPRPRYSVKTRKKTVVHEPPKELTRYKWKPWAKQPESPLEKESTPEPKPTKKPSKKPKKPPTPIESMDKKGLLKELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYV4</accession>
    <name>A0A9P6MYV4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HMG box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_006537</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000323">
        <property type="protein sequence ID" value="KAG0018937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYV4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01389">
        <property type="entry name" value="HMG-box_ROX1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051356">
        <property type="entry name" value="SOX/SOX-like_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45789">
        <property type="entry name" value="FI18025P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45789:SF2">
        <property type="entry name" value="FI18025P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="5">
        <location>
            <begin position="108"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="3">
        <location>
            <begin position="108"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="43"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="83"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="243"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="85"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="243"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="278"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0018937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="553" mass="59884" checksum="C170EAE19DFFFB22" modified="2023-09-13" version="1">MNTYDKQQERRKRRPSSASISTKLSACSSTLSFSASHSSIASSTTSFTTPLTTSSTSSTSTSPNPVSNTNLALTCIPITPITDMVPSTNDSSNPITPLQTVTRRSKGPPRPSNSFILYRKDQVPLFPKMTAAELSRVIGAKWADETPEVKARYAKLAKESARLHAAAYPGYRYSPQKRDNSSARAVRAAKSAQAALKLTAPGMEFASRPTFTSQHSQECPTFMRIPNSYPYPTNKVNNTPLSTSAPSSFFRQPTRTSGSFQVNQGNLMESSFQLPPSRTKKRTPFRSPHRQTKAMTASPSLFFVSSHDQKPLVPFVPSAPSAPSALPTASGSSGLHISLTAMNWPESVGTVAPLPGPTGAHPSLMSMNSSNYIYSSAGNLNMPSYSSEKGVPSSIYLNQLMNADITAAMGMNPPNRETTHNSSLDNSPYVQPVSSDIDYQALIFSGLPCPIPKYTQSSHEQYRSFPMMKTESVFLSPAMMEQDMDVSPVLSVCSSYSSTMSSYSPSMSSYSSSMFSSLLQDRHAGLAANDKQMDSQDKTQADLVAQLLGQQLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZQ3</accession>
    <name>A0A9P6MZQ3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_005175</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000257">
        <property type="protein sequence ID" value="KAG0019850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZQ3"/>
    <dbReference type="OrthoDB" id="2439595at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="191"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="37"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="99"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0019850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="472" mass="54125" checksum="92E7EC1D3AEFD37C" modified="2023-09-13" version="1">MTECGHTEELVSPAGHGEHPPPTPQADSRASDREATANLSQLSTTETTQHVQPRLPRDNSSQAFSDANESGTNADQGTPSLPLVKGAPPAKPDRHQRDSPSSPRAAQPQQGRHEYRPMQPPDYRQISRPDLEHLYSDMRRKYTDAKKTNQHLINAVHEQKRIQEDQARRLDHQSKDLKEYSRQIEAGLAKNQSMAAEIERLRHSNDQLTQQNGELKVKCNKNAERYRELDKEYRDLMRNIQVTDDDHSTIYQRLTNIRTTIENLIQKARRSGSMNKELAVEHFRKSGRSNELPILEANLERYNLDLYMESAVMLTLIDNFFLKPLGRIFGQAQGFEVLRNWVAQKDKKVAARWRQQLCVLVDQDDVAKKFKEDEILRVAGELRSLVYKVYTNVDMESKILGLSRDAFDLSFAMYGMEHEIYPFVTPIGTPFDDETMNTPQSSNPDGKVSLLVFPAFKDDIDLFKIPPKVWCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZU0</accession>
    <name>A0A9P6MZU0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">E3 ubiquitin-protein ligase rbbp6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">RBBP6</name>
        <name evidence="10" type="ORF">BGZ80_006518</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000322">
        <property type="protein sequence ID" value="KAG0018945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZU0"/>
    <dbReference type="OrthoDB" id="106784at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16620">
        <property type="entry name" value="vRING-HC-C4C4_RBBP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014891">
        <property type="entry name" value="DWNN_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033489">
        <property type="entry name" value="RBBP6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025829">
        <property type="entry name" value="Zn_knuckle_CX2CX3GHX4C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15439:SF0">
        <property type="entry name" value="CELL DIVISION CYCLE AND APOPTOSIS REGULATOR PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15439">
        <property type="entry name" value="RETINOBLASTOMA-BINDING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08783">
        <property type="entry name" value="DWNN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13696">
        <property type="entry name" value="zf-CCHC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01180">
        <property type="entry name" value="DWNN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51282">
        <property type="entry name" value="DWNN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DWNN" evidence="9">
        <location>
            <begin position="4"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="8">
        <location>
            <begin position="328"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="176"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="402"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="605"/>
            <end position="1106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="194"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="409"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="451"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="497"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="607"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="628"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="639"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="683"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="711"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="763"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="796"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="926"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="942"/>
            <end position="960"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="961"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="998"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1024"/>
            <end position="1033"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1055"/>
            <end position="1077"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1092"/>
            <end position="1106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0018945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1106" mass="123153" checksum="37720B15679831D6" modified="2023-09-13" version="1">MSQVHYKFKSSKDYDSATFDGHSISVFDLKKEILIAKGLKGPDDLQLTHAESGEEYYDDATLIPRNTSILVARVPAKPGRGGAQRYLEGSGPIPRGGGMTRNVFEKPNQNTTHDPLGAGVKVYKNTTSLLTENGPPAPAVDTSNMTEEERMKFVFEQSADYWDKTQEGMASATYRPLSKFQGPPRNPPPGGQKPGAPGTSSAPGGAPHAGPYQRQPIEQQQRPPPNTYVCYRCGKKGEHWIQFCPTNNDKSFEPIGIKKTTGIPRSFLKNVESNSLQSKKGVMVTQDGNLVVATTNDYEWKKFHEKSKGTLTSEDAYATAPVPDEMKCPICHLLLKSAVRAPCCGTNFCDECIRNYLVQPPKGEEAFKCQSCQKNLVPDQLMPNLDLRLRVEQHLREWAKSRAMDSGRGITSQTGASSSRSGTPAVDSEGSGQGSSYKRHDSPSVAKVSGEDDTVMGEESSEAGHKRRLSHDNQGSNNGNEHDRDQPSWKNKKPHNNNHNNNNFNHQNFNRNRPQMQGPGGMGPMDPTMMFPDGVPPPGFFEMMQQHDPTLFMDPAFFGANGIPPFMMPGIIPPFGDFGNMPGQGGPGGVGGQGGPDMWGMGRGMPGLPPMGPGFPTPRIGFNDNSGAGRGRGRGGWQDYGNNGNNGNNSNNTNNIRGPGQQQQQQQGYNQSPQRAGARPEGRLNSGSNNLNGRARRSASVEAAQGGGTPNHRNSISSGNGRFDDDIDMSKVPTGPRASRRLSFSDDEDIPKGPRAGPGPEFDYDRRSVDRRSESPPTAPLADRIRNRSASRTRSYSRDRDGRDSKDSSSRGDRDRDRDSGRDSGRDSGRDRDRDRDRGRDRDRDRGRGRDRDYGSRDRDRNRDRDRRRDSSRDKRDDRSRSSRHDRDRDDRRDDRREDRRDDRRDEKREDRRGDDRGSSSRHRNERFDRSNRRDYDNDSDGTQSHNIRETSSGASSTRQKSTDPQRDYELKRQASFGVGARSNSAEENNTQEEEVISFRSRSGAGSSRRSPSVSREEREDRNRGRRNARRGYGRGDDDVDEDEDLGHGEDNEYGRNSTRYNRSDNGSGGSWKQTEQGRPDLLASGLVSSSARERERRDRERRARD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0N8</accession>
    <name>A0A9P6N0N8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">TRIP4/RQT4 C2HC5-type zinc finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_005586</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000275">
        <property type="protein sequence ID" value="KAG0019588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0N8"/>
    <dbReference type="OrthoDB" id="338816at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0180022">
        <property type="term" value="C:RQC-trigger complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072344">
        <property type="term" value="P:rescue of stalled ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039128">
        <property type="entry name" value="TRIP4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009349">
        <property type="entry name" value="TRIP4/RQT4_C2HC5_Znf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12963:SF4">
        <property type="entry name" value="ACTIVATING SIGNAL COINTEGRATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12963">
        <property type="entry name" value="THYROID RECEPTOR INTERACTING PROTEIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06221">
        <property type="entry name" value="zf-C2HC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TRIP4/RQT4 C2HC5-type zinc finger" evidence="2">
        <location>
            <begin position="42"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="206"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0019588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="381" mass="40978" checksum="008584F2731E2CE8" modified="2023-09-13" version="1">MSNNRARKLAKKAQAEPLSEIEKAIRAIDLATESVNASKERKPCYCLATKHKLNVFAPNCLNCGKIICALEGPGPCTYCGNPVVSIEQQQAMVLELKREKAALAKQKAMATSKRKAKAVVPTAGYASKLGGGLTSATGAAGGWTELEHGSSGMTEEEELEEAKKASLAQAHKEKLLEYDRTSARRSHVIDQATDFVLPGDRPNLWLTEEERQIEAAKARQNLEKATAAASGYQRAKVMTIDVVNRRVVVEANAGKHLEEEEEDDAVPEPVSVLDQVKSTSISGGDRHGGRGGAFALNPLLKLGEKPTFIPLKAKSKGSLGGKNMKEVKENVLRIRAEKPKVPRLQYDDGSYAALMDDAQILFSSGSDSQAVLASIVEPSCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0P3</accession>
    <name>A0A9P6N0P3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_005111</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000254">
        <property type="protein sequence ID" value="KAG0019893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0P3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050562">
        <property type="entry name" value="FAD_mOase_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356:SF2">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356">
        <property type="entry name" value="FAD-DEPENDENT MONOOXYGENASE ASQG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="6"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0019893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="351" mass="39309" checksum="27F1D50A00379691" modified="2023-09-13" version="1">MTQNLRVTIVGGGIGGLTLAIILQAARIDYVVLERSSTLRTLGSTIALNACALRLMEQLGLWPAIQRIGKPIGAFHLQYDDLSSIGSIDFRFGESHYGYHGYVMARPQLFELLKSRVPKSKVYLRKQVVDVIQDDHGVVCKCADGSEFWSDILVGADGAYSKVREIMYQELQPLGLLPESDAKNLDVTHFCVLGVSKAMDPEKFPSVKEDYSKFELMIFRKRRFSVWMSPIVDNKVSWCYGGELDEIYSQGSGDQGLNDFWGKGSSEMAQSILDEIRDTPTAYGCSVGDIIGTTPKELVSSVVLEEKLFKTWYNKRVVLIGDGTSVRRTRCNTRHAGWHLSRQPTPRDEHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1F8</accession>
    <name>A0A9P6N1F8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Guanine nucleotide-binding protein subunit beta 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">GPB1_1</name>
        <name evidence="6" type="ORF">BGZ80_004451</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat G protein beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000227">
        <property type="protein sequence ID" value="KAG0020289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1F8"/>
    <dbReference type="OrthoDB" id="10255630at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000020">
        <property type="entry name" value="Guanine nucleotide-binding protein beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016346">
        <property type="entry name" value="G-protein_beta_1-5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001632">
        <property type="entry name" value="WD40_G-protein_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19850">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN BETA G PROTEIN BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25391">
        <property type="entry name" value="WD40_Gbeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002394">
        <property type="entry name" value="GN-bd_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00319">
        <property type="entry name" value="GPROTEINB"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0807">Transducer</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="56"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="144"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="185"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="227"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="278"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="313"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0020289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="345" mass="38407" checksum="D5FEBBCCA1108E1E" modified="2023-09-13" version="1">MSYDMSERIAIARKEAEYLKDKIREKKSALNDSSLKSMSQELEPLTRIGMRIRRVLKGHLAKIYALHWATDKRHLVSASQDGKLIVWDAYTTNKVYAIPLRSSWVMACAYAPTGNFVACGGLDNMCSIYNLRTREGSVKVARELSAHSGYLSCCRFLNDRQILTSSGDMTCMLWDLDAGVKLMEFNDHTGDVMSLSISPDQRLFVSGACDATSKVWDIRTAKCVQTFTGHESDINAVQFFPSGDAFATGSDDASCRLFDLRADREMNIYTHDNILCGITSVAFSISGRLLFSGYDDFNCNVWDTLRGERVGVLMGHDNRVSCLGVSSDGMAMCTGSWDTTLKVWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1G4</accession>
    <name>A0A9P6N1G4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001994</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000148">
        <property type="protein sequence ID" value="KAG0021633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1G4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0021633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="116" mass="13075" checksum="3C02BD4EAC018129" modified="2023-09-13" version="1">MILVASALRWKAPSIEAELGMVREEHNYQSKLIKIFAITFVAVTETRRVQALKRITKAHLVNRQSMARHHHRAGMIKTRTVTTLAIVTSVLLTVTIIPTLDSLMTLNAQGAKIRIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1R2</accession>
    <name>A0A9P6N1R2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">xylulokinase</fullName>
            <ecNumber evidence="2">2.7.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_001993</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>D-xylulose + ATP = D-xylulose 5-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10964"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17140"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57737"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.17"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the FGGY kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.17" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010000148">
        <property type="protein sequence ID" value="KAG0021632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004856">
        <property type="term" value="F:D-xylulokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042732">
        <property type="term" value="P:D-xylose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005997">
        <property type="term" value="P:xylulose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07776">
        <property type="entry name" value="ASKHA_NBD_FGGY_SpXK-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042024">
        <property type="entry name" value="D-XK_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018485">
        <property type="entry name" value="FGGY_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10196">
        <property type="entry name" value="SUGAR KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10196:SF57">
        <property type="entry name" value="XYLULOSE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02782">
        <property type="entry name" value="FGGY_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81995">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0859">Xylose metabolism</keyword>
    <feature type="domain" description="Carbohydrate kinase FGGY C-terminal" evidence="8">
        <location>
            <begin position="1381"/>
            <end position="1602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="217"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="469"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="553"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="979"/>
            <end position="1040"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1531"/>
            <end position="1552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="223"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="553"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="623"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="689"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="719"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="743"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="800"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="824"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1020"/>
            <end position="1034"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1540"/>
            <end position="1552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0021632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1658" mass="183093" checksum="6F4A38281F1024AD" modified="2023-09-13" version="1">MSHQQDNTLIPSPVSPTQETLNAGPQYQSQLETLKSLPVPYGDIYQVLTSYDNIPIKPLSAKVRKAVSDLTLWLETAKLAVLDLGIEVKQEGASGKHDVDEIETIMNRFHPNIEMMMELRDKIGSRPELSETKPDQLDTVDSQDTESCLTKEELQQAAKATQSSWNMLKAMLDEVKGIFASAQARREILTQMENVLVEIEEIGLEIDRLQEERLHQSSDVARSTSTLSSPPFSLSTSSLDANTEDSNKQRNTEALVSLDARIETLAPRISALTTRIEELTSVDIKGNELQDQYKELLNLWNETKTRREKIGEEMKEERWLAVFEQVAKQIESMMESMDRAIIHCQGLVDQIIAMVKDKEIPAAPIDREHLYTIFKSFEAKHKYYAPAVNKMLNMLENGIESRATKNKEVIQKHKAMKDSWELLRGRLDRVELDLDGIEEMLDLLDASIPSHIPTQPAQLPEKPLFAMRRSQVQPEWKSPDLPALFQPPEQDQQQRGRRPLSRSPVQSPKEPPTKSRNRSPLNTKTRHRPWSPAPSVSSMSSMLSPNMFENFRSVSRSTSHSPSRVTSDKPRPWCPSTKTTSPSIPGIPHAPSAAAIYTPRSKSTTRDGREPSPTPEMPPRSGSAMSRTRSTSCTPSMGRESSHLRPVFSPAGSMSKLSSGAPARRPTSPAPGSNGGRKTQPKLPPPVATNASTRPRQNSAPGSLTPQQRRSSSPMPFNRSASVTPASQSSSRQRAFSPPVVTRQRQPSGQGARSVSQMGHYRDQDGSGIQRNRRSSLGAYSTTQSLGGVLAATSKSNTDSVHVSVSGSTSGSASSMGLGGYKISQSDEPTSPSTSSSSSVSSFSRLQPSIHQQKQEEQQRQQQQQQQQQQQQQQRQQQQQQQQQQQQQPKSLKSMRSLQNIKSEAQPITPYMPIRGDELDEEFARILKNSAVSIQVRRLGDGKYYFGGRVEERAHGKLVALGGKTVLCRLMEYNRLGASTEEDSGVSSGGSHSGTEDATLKQPRAPPQAASKTALRRPEPVASRSSRPRASSANRNRKYASMLNVTKNLSRKMQTGNPSPLFLGLDLSTQQLKIIALQPRDQSSDHCSSLETHSSFAVNFDIDLAHYNTSGGVTIQHETGDDEPENRGVVTTPVLMWIEALSLVLDRMKKSAFPFERVRAISGAAQQHGSVYWSSRAQETFQTMETSCGRDLSLVDIFKHAFTVYQSPIWQDTSTTTQCKEIEEYLGTLDLGTNLGSSLAEIRLRGQQRLAELTGSRAYERYTGNQILKIIQKSPDVYGATKRISLVSSFLASLLMAQFAMIDAGDGSGTNMLNIDSKTWDPLLAKYIGQGGIKNQGNTSNTLEEKLGEVEASGNVKIVTFTGDNPATVMAMEAEQGDAIVSLGTSDTLLLYTNNHKASSSLFDEFNGANQTNARLSVGYLCHPVDPNGYLMMYCAKNGSLAREKVRDMYADGDWGQFNTYLESAMQSGDSSSRFGLYFFDREIWPPIKGVYRFQGERPVDEFESEDSGDGKQRANVLAICESQFLAMRIRSSQERSSEPDSSPASSLSPPGISRILATGGASSNRTILQLLSNVFGVPVLSMSESDQKGAGSAAWGAARKAFLFGQGDHIQSESNFHERRSDKGGVILPDLEQTRKYVKQIPEFVRLEGILLENSEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4D5</accession>
    <name>A0A9P6N4D5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Gti1/Pac2 family-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_010169</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000068">
        <property type="protein sequence ID" value="KAG0023188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N4D5"/>
    <dbReference type="OrthoDB" id="5572844at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018608">
        <property type="entry name" value="Gti1/Pac2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28027">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATOR MIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28027:SF2">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATOR MIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09729">
        <property type="entry name" value="Gti1_Pac2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0023188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="204" mass="23218" checksum="538986D8140CCCF2" modified="2023-09-13" version="1">MSIAETFHGYIETTQDTLIMFEACRRGLLPRICRRLQEKERRIVRSGSVFVFDERESGIKRWTDGLVWSPSRILGNFLIYRELDRRNNGKKSASPIDRASRSNSSDVDSSIEKNKERALVGSLTNSYRFKKNGLIKKTMSIVVNGVSQHMISYYSKEDVLAGRLSTPSSVAGLACLDISPEFLTKQNFRIPPTLDQSFEQCKNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4N3</accession>
    <name>A0A9P6N4N3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Srp40 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_009267</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000054">
        <property type="protein sequence ID" value="KAG0023492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N4N3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006594">
        <property type="entry name" value="LisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039191">
        <property type="entry name" value="Nopp140-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007718">
        <property type="entry name" value="Srp40_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23216">
        <property type="entry name" value="NUCLEOLAR AND COILED-BODY PHOSPHOPROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23216:SF1">
        <property type="entry name" value="NUCLEOLAR AND COILED-BODY PHOSPHOPROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05022">
        <property type="entry name" value="SRP40_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50896">
        <property type="entry name" value="LISH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Srp40 C-terminal" evidence="2">
        <location>
            <begin position="215"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="262"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="34"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="61"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="131"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0023492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="292" mass="31427" checksum="B15D5D42E07A3654" modified="2023-09-13" version="1">MGAPSELFPLIEEFLQDQGCVDTLKSFRKEAKNTLKSSTKPKTTLIEIYNASKKDKEESESSSSESEESSSSSSSESDDDADSESESSDESSDSEESSSSSSSSSEDSDEDSNTAESEETKQESDSDSDNNSDSSSSSSSSSSSSSSSSSSSSDSSSSSSSSSSSSSDSDSDSDSDSDEKAVEKKAVVEETTLQPPAKRQKTEEKEKKPKVQNEPFKRVRAEDVVFINEKLKDNTYMGKGGAENGYGYKAHLDMIVTRGKGFRAEKTKKKRGSYKGGFITNESHSYKFPDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4S7</accession>
    <name>A0A9P6N4S7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007273</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000037">
        <property type="protein sequence ID" value="KAG0023912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N4S7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024368">
        <property type="entry name" value="Ecl1/2/3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12855">
        <property type="entry name" value="Ecl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="52"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0023912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="143" mass="15601" checksum="2A6BFE18D6C79B95" modified="2023-09-13" version="1">MDLNWCPVCEQHIPLAWESSLYCSERCKKADASRTAYPSEIQSFPRNSQKNSFASPSFSPLSSPSLAGYSSSTAAPTSSAYPSPPTSPMSNYVYNKTSNHGGISPPSFSLGQPATPSYDLQLRRKSMTTISVPQYSPKKGFFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4X1</accession>
    <name>A0A9P6N4X1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Exportin 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">XPO7_2</name>
        <name evidence="9" type="ORF">BGZ80_006834</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the exportin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000034">
        <property type="protein sequence ID" value="KAG0023989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N4X1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005049">
        <property type="term" value="F:nuclear export signal receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006611">
        <property type="term" value="P:protein export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057947">
        <property type="entry name" value="TPR_XPO7/RBP17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044189">
        <property type="entry name" value="XPO4/7-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12596">
        <property type="entry name" value="EXPORTIN 4,7-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12596:SF2">
        <property type="entry name" value="EXPORTIN-7 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25795">
        <property type="entry name" value="TPR_XPO7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Exportin-7/Ran-binding protein 17 TPR repeats" evidence="8">
        <location>
            <begin position="450"/>
            <end position="712"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF25795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0023989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1155" mass="130731" checksum="776F9F166EEFA565" modified="2023-09-13" version="1">MMTPSLDLHSLEQYCETLYNPPNPSSRIQAENILNYHFPTFSAGFSANGGASASSGGAESANSHIPNIDSPIKSALLCRNLLENSKNPYSLMFATSRLKTLVDDHFTGFTTAEQHGLRTFVLQYVYQNLELPPFILAAQAQLFAVITKLGWNENQEFRPLLDHFQVFFQQSVGHRILGIRILTAVTTEMNIPGTRNVVKHRKSAVGFRDSQLLPIFQAALAMLQTVLQSRLTDPDAEKLKEAILQLMKSCLAFDFIGTSYEESSDDVGSIQVPAGWKVVFEQPGYLDVLWECWKSFTGPVSVLVMECISQAASIRRSLFSSDNARNTYIYQIMQETIWTLTTTAGQNKLQDVGNFHEFCRMLSRFKNTFQLAEVCDYKDSKQWLSTIGDFTAQGFHSWKWSPNSILYLLTFWNKAVSSLSSVKQETEHFIESTTVNLSRAYLNSRLDCVHAAMDGEADDPLESEETLILSLDMFANIVRTKYTESGRVIVEKFKDLSLKYRELIQRASALSGTTTPPIGASDVKESLLVIEMQLTWMVYIMSACIGARVMYQSTSEQDQMDGEFACEILGFIHQLQVWTAQRSLYLASADAHLYIQSSIIYFYSQFRTTYIGDDSSKAVKVYTQLSARWGLNTPNQVLDVIMNSSLGNLRSSGDPAWRMQEDQLVLRTLKLFMNLSAGYSSVKYIRKLDTTKALLKNHNSGDFHFLDPKRKSSDTDVARCRTIYYTMLSRILFAEDNVDADFWRFVKPWEVTLNQITLAFGGKGGLGEEDIRLILLGVFKDLRGFVTSISNRRQFNLFYEWFYPAYTPIALRAIEIWPQNELAIAILRFWNEFATNKSSRVTFDSSSPNGILLFRETSNILYTYGQSLLSRPISSESNRWSEKYKGIMLYFNIMSVSLSGKYANFGVFKLYGDKALDRVLEIFFQLMLAVPVDDMVSFPKLALSYFNVIDVFAADHMTGMPSMPHPVLGYIFRALGEAIPVHSVEANTSTMACSAIDKIVTFVLNWLIKNKLRKDGDVEADEMLDTFHDVDLSSSTSGAHVQHRSGVELDSSFGGNNLFAKQDQQETHWLVEYILSNKDVLSFLLVVLFQVVVFENRSNYWSLSRPLLGLIILNREFFSGYTESLVRAQLPDRQDQFRQAISMHVLTVNMGPGAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N539</accession>
    <name>A0A9P6N539_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_007982</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000042">
        <property type="protein sequence ID" value="KAG0023800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N539"/>
    <dbReference type="OrthoDB" id="16434at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032053">
        <property type="entry name" value="Ribosomal_mS34"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16053">
        <property type="entry name" value="MRP-S34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0023800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="117" mass="12874" checksum="AFB5FF826FCD647C" modified="2023-09-13" version="1">MSTIAKEILTKSTLPFISNSTKPRNLYRALKVMDANGVGETVTTTKLIGKGFSDCYYKVTSVKLRGPELNHGKAYGVEVWKGKVLNEGKAVEIRGGLKWNWVKYTPTADHIGSTIKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N560</accession>
    <name>A0A9P6N560_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Dolichol-phosphate mannosyltransferase subunit 1</fullName>
            <ecNumber evidence="13">2.4.1.83</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">DPM1</name>
        <name evidence="15" type="ORF">BGZ80_005691</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a di-trans,poly-cis-dolichyl phosphate + GDP-alpha-D-mannose = a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + GDP</text>
            <dbReference type="Rhea" id="RHEA:21184"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5 13">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Component of the dolichol-phosphate mannose (DPM) synthase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 13">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 13">Belongs to the glycosyltransferase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.83" evidence="13"/>
    <dbReference type="EMBL" id="JAAAID010000028">
        <property type="protein sequence ID" value="KAG0024144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N560"/>
    <dbReference type="OrthoDB" id="2603at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004582">
        <property type="term" value="F:dolichyl-phosphate beta-D-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006066">
        <property type="term" value="P:alcohol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006488">
        <property type="term" value="P:dolichol-linked oligosaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006720">
        <property type="term" value="P:isoprenoid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035269">
        <property type="term" value="P:protein O-linked glycosylation via mannose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06442">
        <property type="entry name" value="DPM1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000036">
        <property type="entry name" value="Dolichol-phosphate mannosyltransferase subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039528">
        <property type="entry name" value="DPM1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43398">
        <property type="entry name" value="DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43398:SF1">
        <property type="entry name" value="DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 13" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 13" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12" id="KW-0464">Manganese</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyltransferase 2-like" evidence="14">
        <location>
            <begin position="8"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00006739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU365083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0024144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="240" mass="27107" checksum="7CF93D9F56891360" modified="2023-09-13" version="1">MAGQHKYSVLLPTYNERENLPVIIWLLTKTFQENDIDYEIIVIDDNSPDGTLEIAQQLQKLYGEDRILLRPRAGKLGLGTAYIHGIQHATGDFIFILDADMSHHPKFMPEMIRLQQSKNYDVVTGTRYAGNGGVYGWDLKRKVISRGANFLATVLLRPGVSDLTGSFRLYKKDVLSKLISSCISKGYVFQMEMMVRARQFNFTIGEIPITFVDRVFGDSKMGAMEIVSYAQGLLKLFVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N575</accession>
    <name>A0A9P6N575_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RanBD1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_006082</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000003">
        <property type="protein sequence ID" value="KAG0024808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N575"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053074">
        <property type="entry name" value="NPC_Nucleoporin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000156">
        <property type="entry name" value="Ran_bind_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38697">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN SIMILAR TO S. CEREVISIAE NUP2 (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38697:SF1">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN SIMILAR TO S. CEREVISIAE NUP2 (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00638">
        <property type="entry name" value="Ran_BP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00160">
        <property type="entry name" value="RanBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50196">
        <property type="entry name" value="RANBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RanBD1" evidence="2">
        <location>
            <begin position="380"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="303"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="340"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="344"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="363"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0024808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="507" mass="53231" checksum="D4C9773FA35D15DF" modified="2023-09-13" version="1">MSSPISRTDSPTLDEHAKRKRDEALGKQSEGVLSNGSETEADPEAVPPKKMQPEVDAGTVPVSKAEVKQIQRNLKTMPLEDTKSPSNAENENKDMDDVESQGSNEDQTQDKLMEESSHLPADKADTPNGESTPSSDIGDQDTESTNATAHSVLNEKNGKEIKAAPEKTTTSSIFGSKSLGSGAASSASPFASLSGNVFGSSASDSKGSNATSSENAFSTAGKSGVFGSKSTSLSGGFGNTSAASPFASAAGTNVLGNDSPKSVFGQSSSTSAIGFGTLPENSTDSTAGSVFGAKSIVGSVSGAGTPLQKPSVFPARLPSTRATSSTFGSFNKEASFNSGSFMIDQDSSQDQDFGSLLSQDTGDREDPEQADGEENFGTGVFTNADQIDVQTGEEDEISIYQTKGKLYADTEKTHAWKERGKGAFKINVNQSDTKLARLVMRTDGALRLILNVAIFEDMNIVITGEKYVRFIGIEEGKPISFLLKVKDGVVANEIVDNIRRASERQAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N684</accession>
    <name>A0A9P6N684_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_002429</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000016">
        <property type="protein sequence ID" value="KAG0024478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N684"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="413"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="448"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="193"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0024478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="489" mass="52459" checksum="A3F941C594D508DA" modified="2023-09-13" version="1">MSPTLAYESKTLKAKKTSRRPTTDDVFNTQHLRSASAPSLGLAQPKSYTSFITELISAFNSLSSPSTAPTSSSTLHAFFQGVDHEAHVDERQKRKVVKALQLADPAKVNEVISILKAMPDPTSSLVGPTNQKSLQKELAKQEQLDKERTKQEQLDKELTEWDKIEKKKYWETQKSNDQATGVVDPESCKGLMSPSWWLSSTEPPSPTPTGAAPNKGTLTKASSTGTLFKSSWLTSKSKSEINDLSANETTKKSLSTGEQIALAAASLLATVAVAKPKDPKVGATTTTTTDCTIRKSSSISRQSSMSTIKPAKLKALLPTTKSSTATGTIKNPPAKAVVPVTSDTSSSSPSSLIGSISAITRQFLNLDGPPSASMISACTFWWGYEIYIPHKSIATIEHVTNTSQVFFNILSNAISGVPGLAALVPIAKIIAAWVGYQWTVIKSENRGKGVIISAIWILPVALASRAWDLPGHEDSTFQSLKSKLSLVGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N689</accession>
    <name>A0A9P6N689_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HPt domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_005240</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000026">
        <property type="protein sequence ID" value="KAG0024202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N689"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009927">
        <property type="term" value="F:histidine phosphotransfer kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043424">
        <property type="term" value="F:protein histidine kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00088">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.160">
        <property type="entry name" value="HPT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045871">
        <property type="entry name" value="AHP1-5/YPD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036641">
        <property type="entry name" value="HPT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008207">
        <property type="entry name" value="Sig_transdc_His_kin_Hpt_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28242">
        <property type="entry name" value="PHOSPHORELAY INTERMEDIATE PROTEIN YPD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28242:SF52">
        <property type="entry name" value="PHOSPHORELAY INTERMEDIATE PROTEIN YPD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01627">
        <property type="entry name" value="Hpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47226">
        <property type="entry name" value="Histidine-containing phosphotransfer domain, HPT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50894">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HPt" evidence="2">
        <location>
            <begin position="76"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphohistidine" evidence="1">
        <location>
            <position position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0024202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="183" mass="21046" checksum="248786160EEAA74B" modified="2023-09-13" version="1">MFDSDHLETDCDIELTGHWLLAFFPLKPKWRECQHVEVDEVDTDPEADEYEEDDDDSEIIDHATFDQLLEMDDEEDREFSKSLVWNYFEQAELTFDKLDGAMSQLDFPELSQLGHFLKGSSAALGLKKIKASCEKLQLYGICKDAEGTGTITEDEAKDLIQSLLIQMREEYGEAQLYLKALFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N6B4</accession>
    <name>A0A9P6N6B4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_004524</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000023">
        <property type="protein sequence ID" value="KAG0024284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N6B4"/>
    <dbReference type="OrthoDB" id="2373783at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31639">
        <property type="entry name" value="F-BOX PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31639:SF256">
        <property type="entry name" value="OS07G0242900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0024284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="673" mass="76567" checksum="22E3734984C20FF6" modified="2023-09-13" version="1">MERNLEPVATELLPYIKQYALHIPEIVGMIVAHLTSTEILFCRGVSKDWSRIFSPFLKLHAIYWDHGVLYKARFEERLETLGPYVQSFKEVYPARDDLDKIKRTCPNLRRIGFFLRDKSLPDTQAMVKFFQAMKRLERVDVFSHNDLLMTSCLVSLASCQVSLDSESTLPTVASGQTISAQHLPCDPLRVLEVGIAARSMASPTIEWDLLEAVLTRHQMIQDLTIREAHLREASDFTNSGGISWARSASIIFGQQAQQKWGVMSSELKEGNEGANRMEYLNSILGIAAPESTVFNYLETLVFDNVKISEELFVSVVSRCPSLKTLNVKLTGVEMPMHAWSSCLPCCPQLANIIVNNEYGGVCVDIPDVWTLAPSLRTLHVTRSRGPEVYFSDVESHPGLENTVLSQTPHPGYALVSLELCCGISITDTRVRSVMSHCRFLERLVLELLYFTEWMQGAEQSTPFPEWSCRRSLKSLELQTIYRGNDQQFDERTHLFINRLKDLEVLEKLILPGKLLSDLSESGVELYGAFRDLLARLDIWNDQYFAQAQRQHVKLDCDTNQEATDLQHQQLSQELGYQHAKQCHVWTRDGSGPVNFIPQMPSVKNVTLTSPSDTRFALEMRHLHILMEALPGVRTIWTSKNLYGMDCIPRFNYFYNRFQELYGLTGVELILGSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N6S7</accession>
    <name>A0A9P6N6S7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Rieske domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_008906</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000005">
        <property type="protein sequence ID" value="KAG0024748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N6S7"/>
    <dbReference type="OrthoDB" id="426882at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="entry name" value="Rieske [2Fe-2S] iron-sulphur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="ISP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rieske" evidence="6">
        <location>
            <begin position="156"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="87"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="97"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0024748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="214" mass="23177" checksum="2F4E5E54AC6238B9" modified="2023-09-13" version="1">MSLSPNATPNSSPPLPGSPAHDNDNLIPFTPSTTTSSTTSTEPPLSLTITSATTLSVTSTTESTITLAEQKSVPEVAIDAVSGSLSNLTINSSDSKSSTDTKEPKVADEEQVEELSPEEAKLRANGLKSTHRPGFYIHINSPRRLRITTKSKTFDLDRYCPHANADLLKWGVLRTDMTLRCGVHYWGFDLVKNGQCIAHPDETLNACPAPELEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SR42</accession>
    <name>A0A9P6SR42_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Reverse transcriptase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_008535</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004652">
        <property type="protein sequence ID" value="KAF9992484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SR42"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9992484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="175" mass="20586" checksum="328FC24E65875CA3" modified="2023-09-13" version="1" fragment="single">MFLHQMMEADLRKLLRMQSHRRAHANWTNSHRAARCFLFFRKDIDWLATHNVIHDKIPMATWTTFFKNSHARTFNIKRAHDMLPTLSSMYARYPDLYSSDGCLCCDSNTPEHNEHLWRCSASWSTRRAIWDKAIQDINNVGANIVRDLKSEHPDDDKLTWTNSPSAPLEMILETQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SRD4</accession>
    <name>A0A9P6SRD4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Crinkler effector protein N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_008061</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Host cell</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004263">
        <property type="protein sequence ID" value="KAF9993675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SRD4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043657">
        <property type="term" value="C:host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045379">
        <property type="entry name" value="Crinkler_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20147">
        <property type="entry name" value="Crinkler"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Crinkler effector protein N-terminal" evidence="4">
        <location>
            <begin position="19"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF20147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9993675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="135" mass="15170" checksum="5935EE253C0DAD3A" modified="2023-09-13" version="1">MTNQPPSLGTKDSAKGFKLKLYCIVEDDSNAFPVNILSNESIGDLKKAIKTAKKPDLDNIAADNLTLWKANIPIVKDTNYRKVVDDVKKDRNNKMGPADFVNKHIPKVLPKMIQIVVELPQRVRKRDQDEDDAGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SRL1</accession>
    <name>A0A9P6SRL1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_008006</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004217">
        <property type="protein sequence ID" value="KAF9993855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SRL1"/>
    <dbReference type="OrthoDB" id="8904098at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006857">
        <property type="term" value="P:oligopeptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000109">
        <property type="entry name" value="POT_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018456">
        <property type="entry name" value="PTR2_symporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11654">
        <property type="entry name" value="OLIGOPEPTIDE TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00854">
        <property type="entry name" value="PTR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01022">
        <property type="entry name" value="PTR2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="125"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="159"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9993855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="186" mass="20446" checksum="AF496BEDAF66BE90" modified="2023-09-13" version="1" fragment="single">MAEKQDVDIAELSLEEKGLAVTHYDLLTEHEKELLELEARINAELDAKIAANPTKMPKAVYFILPNEFGERFCYYGVQPNLNKYFILVTGMDAANAKQFSTAFTMLAYFFPLIGAALSDSFLGKWWTIISFSIIYAIGMIMVTIFAIPNLLGPVGTVSHFLTFLPMLVIALGTGGIKPCVSAHGGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SSZ8</accession>
    <name>A0A9P6SSZ8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006757</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003350">
        <property type="protein sequence ID" value="KAF9998572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SSZ8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9998572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="87" mass="9606" checksum="DECD14B6FFA005CA" modified="2023-09-13" version="1">MPPPSMPMTTSGPLPPISKGRRPIRALQAQAPLYGMGELKSSLNQDESRGGNFHKNNSLHDDDICPDLSYSGIDSYHFELNQNRPVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6STJ7</accession>
    <name>A0A9P6STJ7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_006158</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003025">
        <property type="protein sequence ID" value="KAG0001585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6STJ7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0001585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="87" mass="10061" checksum="C755F1FC3D92E2B9" modified="2023-09-13" version="1" fragment="single">MTAGEMKERLNEVYKDLSAYQSELSENSSARYVLCGSFHTNGVQLYLDAINTRVIAEHKYIRSENRHKSDMKLMLDHRIGYGSYLRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SU16</accession>
    <name>A0A9P6SU16_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CBS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_005850</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002885">
        <property type="protein sequence ID" value="KAG0003102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SU16"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050511">
        <property type="entry name" value="AMPK_gamma/SDS23_families"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13780">
        <property type="entry name" value="AMP-ACTIVATED PROTEIN KINASE, GAMMA REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13780:SF128">
        <property type="entry name" value="CBS DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0129">CBS domain</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="CBS" evidence="4">
        <location>
            <begin position="70"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="4">
        <location>
            <begin position="249"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0003102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="298" mass="32925" checksum="5D14E39F32676D66" modified="2023-09-13" version="1" fragment="single">TFSRSLSTDISTTLRITSPSLMPMTFYLPWRQVELMLEKGFSFESGSTPDTEFLTMPVAILVGMTKSSSKLWTCQPDLPLTQLIELFTKNRVHRILVLEKNLNKTGDTDDDDDEAAEPREEPKGRLVSQTDVIRFLLENNHALGPVLEISAEQIAGHALRFSDDYLDANSANRLKQSTASITINCQAWIALKKMSTTHASSVAVVDSDGGLVAEMSAADLRGINPSRIQDLARPVLVYLKAQQGGDLKRPLSCKVRFSLGQLLSGLVLNHAHRSWLVDDEDRPVGCITMSDILSVLLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SVX0</accession>
    <name>A0A9P6SVX0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004458</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002271">
        <property type="protein sequence ID" value="KAG0007610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SVX0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="523"/>
            <end position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0007610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="621" mass="68724" checksum="5BC28DEDE3DC9108" modified="2023-09-13" version="1">MFVNDGSLYLIKAEVVVLAVIIKLVLMAFLTHLALLYYYSAGDWHSAAQISNSAGNVLSLLSSPKHRHGVARGTTKTWLISTGFLVLAFGANYIGDLMQIVWSPTLRDFAQPVDVYLTNTYNVTIPYDLYSQFTVNGSIVPDALLDSRYNPVLNYTTLSPSTINGESISYFTIDYDGASVLDNVNKPHPCSPDVSICQGEMMSSVVTPCPVTYNLSSTYANSTKSIPIPCPTLYEFVPVTSYMLPIQSRIAQYMFVSEDAWHKDNKPNPIGTNIRHSFRLSGIPYPDGRGLILQHNVVSYFPLSMDELVRNGTGTTWPSTKCAETLAKFHFTNTTEACSNATVNSSNATTSQRMFINTMEGPNETTMRYCIISVSGVEFVFSLNCGMQYLKIGYLGPHVPFYRKDQQSVFYIQNQGSSDVWCSGSEDGYQRCILDDQSKSYRSISSRGYGIFYASNTVPVEQQTISQPDLDIQIAKIDEMTNLTREIFLREYSIGSNDYILGGVPVRGVGHAIMIRYRVNISIFAVLAVLVALLLISVVVLHFIVLPSHYTASAFDVFRVATSPDTRRVNDPGKADQDISLRLNSDGNITITNNGAIIGPLNDEYPLDSRYSPSKVSLLPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SW92</accession>
    <name>A0A9P6SW92_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003841</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002039">
        <property type="protein sequence ID" value="KAG0008107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SW92"/>
    <dbReference type="OrthoDB" id="2348921at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="38"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0008107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="649" mass="73396" checksum="7F0127EF244AD686" modified="2023-09-13" version="1">MDNKRSSIISRFHPLRNKNRISTGTDSLPAPTKPLICSPLSPVSPVSSMPSPLSPQKLSPPDCSPPTKAPVNPLDIPEILYRIGQFITLWKYSEQGYTPQFVPETLVRCTNVSRHWHNVMTPIIWYFYDDTLMSSIPREVVHRNAHFIKVLNHRHLYGGVGYKCRNLVQLSTSPWVVGAEDLIKQNTRLEKFSWHTHTYFLTIRQPIYDALAGVRAGFNNSNTSGLSILRILEFEGSQLDPRQLFPLLENHLPGLQILILHNVTFVSEESIRADTTSELSKITWNPQAQFTQIREVRIGKGISRGRRPLIDILTHCPRLERLVIEGLDESWISANNIHHKKSTDLFGLLINNLEQSCPNLKSIVYSPHRIGGQTQLLDDAKYTQLIRCMDPSTRDHSKVVGDSSRNGGIKGSNNVKWGGDRSKSRDTSRNYIIGEEENKDYAVPSFTADMSCLDTNSALALCNMSMTMESIALRLHSCRSETTARANMLNAHQILTSCRALKHFTLEHEALLAPWEMVTPVSIALLLYDNPWVCTRLETLVIDGVKRPSDFGMDKELANQASRLGGTKFNRFGCLLLRMQDLLLLAGLGSAEKAPQISAVINMGYREALLKDIDLLQEKLFHQLARLKNMRQLTWNGDTFRDFSKLAYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWU4</accession>
    <name>A0A9P6SWU4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cytoplasmic tRNA 2-thiolation protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3 5" type="primary">CTU2</name>
        <name evidence="3" type="synonym">NCS2</name>
        <name evidence="5" type="ORF">BGZ80_002880</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with NCS6 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CTU2/NCS2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001733">
        <property type="protein sequence ID" value="KAG0008952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWU4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016783">
        <property type="term" value="F:sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032447">
        <property type="term" value="P:protein urmylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002143">
        <property type="term" value="P:tRNA wobble position uridine thiolation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03054">
        <property type="entry name" value="CTU2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019407">
        <property type="entry name" value="CTU2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20882">
        <property type="entry name" value="CYTOPLASMIC TRNA 2-THIOLATION PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20882:SF14">
        <property type="entry name" value="CYTOPLASMIC TRNA 2-THIOLATION PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10288">
        <property type="entry name" value="CTU2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="530"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="543"/>
            <end position="557"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0008952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="566" mass="62385" checksum="D40B796DFD0550E7" modified="2023-09-13" version="1">MSCSIDEPTMTVAEKRAKARAVHVGFCCKCKTTKSTIIVRYAEYCDPCFLIALDSKFRTALRNARPYRVVTPENVMLAFSGGSSSRSLIHLFDVFHSLPPEVVSNKQQPKIYNDIHVCHIDESSLFESTIQSQEQTDSSINHNGLPQSTMVQAQSIVAKYGYKFHGVRIEDIYDPEWTDSRCFEAVATLITSLPRDQLVTSGQAPELLSKILPLSTDATFNNKIETPSPDQERPKLSQQEKIEKLKTLLGVCTTLTAREMILQHFKSSLLIQLAKRAKCTILALGDSATRVAIQIIGLTATGRGFSLPHETSLLSNWVQDCKVIRPLKDCLVKELDTYCSLNSLELIERHSANLDWSVKTKGDVKSIKRLTEDFITGLDKDFPSTVATVCRTAAKLTPPEVTYENKCPLCLGPVQEGVQEWKERITVTTAPPDSSNNATNVSDGCCSSNGAVCCGGGANNGSASSCLPPLSKDQDSVATLPFSSLLCYGCLTNLRDLDLKSMSSEDSQEGSLFVLPPYVAETILDRSGYSSLEDYKQPTSSSRDPRESLREQIKDFLIDSDDEDEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXZ9</accession>
    <name>A0A9P6SXZ9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tetratricopeptide repeat protein 14</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">TTC14</name>
        <name evidence="3" type="ORF">BGZ80_001309</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001298">
        <property type="protein sequence ID" value="KAG0010619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXZ9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039190">
        <property type="entry name" value="TTC14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23184">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23184:SF9">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13414">
        <property type="entry name" value="TPR_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="34"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="131"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="258"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="90"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="132"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="150"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="261"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="329"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="368"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="389"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0010619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="607" mass="66224" checksum="579DD9DA00A700AD" modified="2023-09-13" version="1" fragment="single">MDSFAAGIDCAQKGQLDDAIKAYSQAIQIDAKCVEAYVARGCTLANIKKWRAAIMDFRAALSLDPSNVSAQQYLESTIAQEEEHRLNPTIDDTPSNGAENSSNITMFNGGSNLDNINEIVLDTEVLESVIENSNGNNNNNNNNNKGNNERKKKKKKKNKKKNLSEHETSFEIGIAIEVETGVEIEVGIEAEIGVGIEAETELAIGMEIDTQGGHRAVVDPDRAHLVHDRGQDQSLDQGQDRLPVLGVDRGLEAQQGITLGIDHDLDREVTGKDQDRHSGQTHDNEDSKTNKDDETSEKRGGKEAEANKDRKEDAELKDSKDGKNGGDQKRRRSKSNSRSRSREQSRSKSTRTAGPDHARGHSPRHQSQAKDQDKDSKGADTHLTNLTESNKDNRDMLHHGGDRKDASKDEARDKKEPHIKRGDKEAINSSKDRLDDQKELAPDAQKKDDKLSIETLGAKGRGVLENVTHIMGEEDAEIGRLAPQRAKLEILQILKVAPGAGAEPEILTTGSKVLQLVSATPLITIRTKVTDVNVVGRQVGTGSAITVVKVDLIVAAGLVSRRTIRIKSRRGREVDQIVVAVPMQTKVESVVDPAVVVDALEIGLAHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYH3</accession>
    <name>A0A9P6SYH3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">UV-stimulated scaffold protein A C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BGZ80_000621</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UVSSA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001130">
        <property type="protein sequence ID" value="KAG0011531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYH3"/>
    <dbReference type="OrthoDB" id="5594015at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000993">
        <property type="term" value="F:RNA polymerase II complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009411">
        <property type="term" value="P:response to UV"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006283">
        <property type="term" value="P:transcription-coupled nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018610">
        <property type="entry name" value="UVSSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049431">
        <property type="entry name" value="UVSSA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049408">
        <property type="entry name" value="UVSSA_N_a-solenoid_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28670">
        <property type="entry name" value="UV-STIMULATED SCAFFOLD PROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28670:SF1">
        <property type="entry name" value="UV-STIMULATED SCAFFOLD PROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09740">
        <property type="entry name" value="DUF2043"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20867">
        <property type="entry name" value="UVSSA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="UV-stimulated scaffold protein A C-terminal" evidence="11">
        <location>
            <begin position="484"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="366"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="441"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="614"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="377"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="441"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="614"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="701"/>
            <end position="726"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF09740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0011531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="726" mass="82046" checksum="120F80288B93D615" modified="2023-09-13" version="1">MAININERESLSALILAITKTGDLYLDPAQVKQVKAICKKSDANAKIAYELLMIQLQRKHAQIRFSSTQLIAELFQRSHVFRELLVADYSIFLQLTVGIHQNTLPPPAVFAEKTKQLAISLTNEWNSKYGAVYKQIVLGYEFLRYHLKVDFTNLTPVTEEARSAEQRAQEEMSRRLRKKRYDKAAAEIDDKAEDIQENLRKMNSCFDILVPKLDDDVALNALFAADLNTSEERSTEAANDQMEIMEEEGESSNIIDEELPRHDPIGVYENALGSNRYKLTINVNRDNPVDVTESEDNTELFTTLRECYLLIIKKHLPMVVEWLDVLMKADHEPGEQRLEYDRLLRMAIDFKKNVVDAKSKCEDLGVNMDTMYGPDENNSDEDGEELEEVEIPVNSDDKKKGKQVKRNVQKIEPRKPRNPVFAMHGEDVLEDDPTYIGGTRISSMRSSGASVAELDSSSKTKVVSNTPTESKGSDTESREDLLARAPVIPWDDDLAVWDKKEMAFNTSGLEYSHRFLGVGDGSNMVSQETLDRMKMRTRIYNPELPKVIKACRFPMSNGRLCPRRDLVRCPYHGPIVPRDENGQIQVPHEEGGFVSEDGGLDDTEEVDLINRAIAAASGSSSSGSGTKSRRPKEKSTWEDIEDDVNLALGLEKIEPKRRRGQANDATSKRKKGDKPPSALVNISKAPDSSRVRLLKHVGSKASKDSVEQDRRMEKATLSKDSRMHRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYM6</accession>
    <name>A0A9P6SYM6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_000358</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001070">
        <property type="protein sequence ID" value="KAG0011899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYM6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="214"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="277"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="384"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="114"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="214"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="282"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="411"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0011899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="421" mass="45065" checksum="A717892280C2462D" modified="2023-09-13" version="1">MRRADATPEQFWRVPTRQPSRKYRRRLRELFKGKQPDSSSSAKVTVLFPPPRPPRPTSLNLGFLVPVVPTIVCHRKIRKQASVRRAGKNIASANKTKSSATKNESGVAVKIGPSTTTTPTAITTTTSNGSSSVKSGSSTVDSDLSTIKSGSSSTTSKNSLEIPVTLASTRESEETKVSPEVKKAQKAFGFGAVSQSMMQAKSKAKVFLDHFHISTSRGPSSSSSSSSTSSLSSMSCPTSPISPSPSMISRPSSPSLPPLPLLPLLPTFATDDSEFCEVVPKKGPPTHAPPPPPSTPAPASQGPKVAKVTIVENNVSREPTKSESGLYKVELSSTSSLVQRKPRITSKAGIYSQQLAALNKLEFGDASGQSQQSTQCRCRCRCHRVSSASYRKSRMIGRSDSRASTVSSPRPSKDRRNSKLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYS6</accession>
    <name>A0A9P6SYS6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Bifunctional AP-4-A phosphorylase/ADP sulfurylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">APA2</name>
        <name evidence="4" type="ORF">BGZ80_000357</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001070">
        <property type="protein sequence ID" value="KAG0011898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYS6"/>
    <dbReference type="OrthoDB" id="10267950at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003877">
        <property type="term" value="F:ATP:ADP adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009163">
        <property type="entry name" value="Ap4A_phos1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043171">
        <property type="entry name" value="Ap4A_phos1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045759">
        <property type="entry name" value="Ap4A_phos1/2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019200">
        <property type="entry name" value="ATP_adenylylTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38420">
        <property type="entry name" value="AP-4-A PHOSPHORYLASE II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38420:SF1">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_5G14690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19327">
        <property type="entry name" value="Ap4A_phos_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09830">
        <property type="entry name" value="ATP_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ap4A phosphorylase 1/2 N-terminal" evidence="3">
        <location>
            <begin position="81"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="ATP adenylyltransferase C-terminal" evidence="2">
        <location>
            <begin position="208"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="338"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="341"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF19327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0011898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="372" mass="41713" checksum="34735C08CF150F3A" modified="2023-09-13" version="1">MSTFLADFDNALSTTYDAALKSGELIFTASEILKSKETGYDVECEICYAPALSKKPHGVLPVVESDPRPTLDRPSTPVVKTIERTNPFLPHAPALYITDASEKHKILLNKFCIVPRHYLVITKEFHRQTEPLSPEDLMAVWNTMMALKNSRDALAFFNCGSRSGASQPHKHMQVIPRETPSPIATLVREHTARRPGRKATQPGDLFSLPFNCINHAVLLQSPEEAMKSQEDILVGAYISLMDAMIMSLREYAERDDLTNEDRDLVTSMRSSFDYNWLMTTEFMMLVPRKQDSSNPVERVILEINSLGFAGMVLAKTPKELKLAQDRGVIELVSETGFGFGREGKSRSEEDEQKRKDEQAAVEKQMDGALSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYY2</accession>
    <name>A0A9P6SYY2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ankyrin repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_000539</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001111">
        <property type="protein sequence ID" value="KAG0011638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYY2"/>
    <dbReference type="OrthoDB" id="341259at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="41"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0011638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="73" mass="8252" checksum="BE8A95D0818EFBEF" modified="2023-09-13" version="1" fragment="single">MIEQKAQRLMTACQEGNLELVNRIASKFESTVELCQVEPSSGYTPLMMAARHGHLEVVEALIRLGHDREEISR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYZ5</accession>
    <name>A0A9P6SYZ5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_011526</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000937">
        <property type="protein sequence ID" value="KAG0012765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYZ5"/>
    <dbReference type="OrthoDB" id="10484779at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="520"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="115"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="238"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="264"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="299"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0012765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="574" mass="62845" checksum="2BAA7CB824F732AC" modified="2023-09-13" version="1">MECTFDICQFQLLNVSTLGEEESKHVAEYHQNAQLTVEVIHEGNIYGLSFVRLRLEEMHFLCMCDKRFLAQSSMSNHVKECPIVKRVVAQSGPQWNETNAQEDPYLTPPPPPPSSSSSSPSSTHPSLPLPSRTLQDTLSSPSRATSLPLGDSREITIFPPRATSLPLNIPQNTVSRSSLPTSGPWDVTLSPPPCPTPPRRGFSRDTIFSSLPLGNPPLSVQPSSGNPPLSVQLPLGNPPLSAQPPSNSSSRSHSAQLPLSGPEDSTVSPPRSSSVSWDTSSSPHRPTVHQSRTHPYERPSASPSLGSASPSLGSASPSPDGASNLDSSFKSTVLRYLRNLSRNQKELVKSVQDQQHILDQHTSELAYLRSQVSETNQTHRPKLNAIHRQIVDEFIVDFKKEVVDEVIKEAVTNINNESRMQVAEENTVGVGHEAMERAIEDAIMETHAQFRNETNVGQMVEDMEDVDLEVKEEVNEVMEEVNGGTGPGVEVDDDTTTRVGSRVWEGKEVPKKEQHLGSYIGVGRLSSPGGRSCSSRQETVEYDTDADTDLNSYGTPDFRDHFETSTPKPASPDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZ05</accession>
    <name>A0A9P6SZ05_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ccr4 associated factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">CAF17</name>
        <name evidence="7" type="ORF">BGZ80_011633</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the GcvT family. CAF17/IBA57 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000960">
        <property type="protein sequence ID" value="KAG0012603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZ05"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.120">
        <property type="entry name" value="Probable tRNA modification gtpase trme, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057460">
        <property type="entry name" value="CAF17_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027266">
        <property type="entry name" value="TrmE/GcvT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017703">
        <property type="entry name" value="YgfZ/GCV_T_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045179">
        <property type="entry name" value="YgfZ/GcvT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03317">
        <property type="entry name" value="ygfZ_signature"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22602">
        <property type="entry name" value="TRANSFERASE CAF17, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22602:SF0">
        <property type="entry name" value="TRANSFERASE CAF17, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25455">
        <property type="entry name" value="Beta-barrel_CAF17_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103025">
        <property type="entry name" value="Folate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="CAF17 C-terminal" evidence="6">
        <location>
            <begin position="223"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="262"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="267"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00093447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF25455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0012603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="340" mass="37555" checksum="ED97FCA75D5757D3" modified="2023-09-13" version="1">MSTASTTSGSYIHLPTRGLLEIRGKDASKFLQGLITNHMPRIENGGSGFFAAFLSPKGRVMYDAFIHPANTPKDADPTFLIECDARALPELHKHIARFILRSKVKLVGVTESYDVYSVLDDSHHQDSTLGQEPAYSNAEVMERLGNMHASIVSLPESYKQGTLEDYHVRRITNGVPEGIDDFIAGTSLPLECNIDYMNGVDFRKGCYVGQELTIRTYHKGIIRKRVVPVQYYKPNDTEPESFQFNKNASHVIPPQSELFLVKDEESSPQPTASSSSARAVRASGKTGSNIGNIGLALVKLDDVTSGGTFNVMDREGAIIRAKAFFPTWWPQQPTSEDNAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZ11</accession>
    <name>A0A9P6SZ11_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">FAD linked oxidase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">GLCD2</name>
        <name evidence="8" type="ORF">BGZ80_011424</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000918">
        <property type="protein sequence ID" value="KAG0012905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZ11"/>
    <dbReference type="OrthoDB" id="415825at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF39">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040171548" evidence="6">
        <location>
            <begin position="22"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="7">
        <location>
            <begin position="63"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0012905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="502" mass="55814" checksum="621AE3E8039BB75A" modified="2023-09-13" version="1">MKVSFCILSVVAAVAYSAADAATTPNFPKAHFNIQFRQQTDKESYYDSLKTYNQLITPKEFPATALPFAVIAPTKTNNKGLEQVVKIAKKNGLRVSARSGGYQSGYSSNMAAVDNKKQDFVLLDLSKLNKVKIDPKARTAVAEPGATGLELYNEAIKYGLHFPGPHTARVTIGGFLLQGGMGIGSRLHGAGVDNVIGFEIITANGKTVYADAKHNKDLFFAVRGGGQFFGVVTKFHLSLAPIVKKPTLVPTYNATSVQIDQIFAIFDRPQATQLLDFYREFDPVAPKALENKVVFVVDAATNNKQYLFASVSAAPFNSSAAVTKSQGEITSWYKTLPTNYATSDPTTYSGVIHGSDASWPDDNLSYYAEDFWFPVPLDPRLQEVLIKQWDKVPSALSSMALNTGTWDSPTRSALGYDRSYSLCIYSTWKRNGTASWDETNKAWLDETVKALKPYTLGYYANELRPKNLKDRDYWRKCYERKTYKTLKVTKNRWDPNNIFKSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZ78</accession>
    <name>A0A9P6SZ78_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">PHD-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_011319</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000899">
        <property type="protein sequence ID" value="KAG0013046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="GO" id="GO:0043565">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15571">
        <property type="entry name" value="ePHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20104">
        <property type="entry name" value="MBT_PHF20L1-like"/>
        <property type="match status" value="2"/>
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        <property type="match status" value="3"/>
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    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="AT_hook_DNA-bd_motif"/>
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        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="EPHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
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        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24216">
        <property type="entry name" value="PAXILLIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13771">
        <property type="entry name" value="zf-HC5HC2H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00384">
        <property type="entry name" value="AT_hook"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63748">
        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51805">
        <property type="entry name" value="EPHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="7">
        <location>
            <begin position="1437"/>
            <end position="1556"/>
        </location>
    </feature>
    <feature type="domain" description="GATA-type" evidence="6">
        <location>
            <begin position="1667"/>
            <end position="1700"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="136"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="472"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="590"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="687"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="904"/>
            <end position="997"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1108"/>
            <end position="1138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1260"/>
            <end position="1296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="2334"/>
            <end position="2382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="142"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
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            <begin position="183"/>
            <end position="205"/>
        </location>
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    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="209"/>
            <end position="230"/>
        </location>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
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            <begin position="245"/>
            <end position="254"/>
        </location>
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    <feature type="compositionally biased region" description="Low complexity" evidence="5">
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        </location>
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    <feature type="compositionally biased region" description="Polar residues" evidence="5">
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            <end position="316"/>
        </location>
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    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="332"/>
            <end position="350"/>
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    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
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            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="545"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="592"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="692"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="712"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
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            <end position="780"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="791"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="811"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="821"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="945"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="955"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1117"/>
            <end position="1131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1264"/>
            <end position="1287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="2334"/>
            <end position="2356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0013046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="2382" mass="264204" checksum="635F4C1EADAAF1CC" modified="2023-09-13" version="1">MASTDDTLDDNVESSAGDTNDLDIIDTHDLDDSSAPTVVKRGRGRPRKSIPSLSTSDSANDGMEVSSPDDASPEGSTLDILNQKQQGSPGGDDKRGKASTIGRCESCMTDDVRIYKYGKLKVCKECEGLMRAATGSNRRHSMTNPATIATLPNTNKTASSSENVATENVLSIEGDQHTPLQEPPTSSRRSSQDSDPIVQSGSNVVVKQEGSSESPSSPTSATSPSHASPGTVDSAPRRRGRKPKARLEIEHQTDEVSSSANNTSENSPTSNTTAHTQIHPESSTSTVKKRGRKPKSTNSDQEPTTTAEILQTNIPEPSNPAGDHTPLEPTKDSGNTSKSTQRGSNKFQTTGAFLTRTASRLLGGQAVTGVDSNIHGYAYQRAVKVLNIDGTWYYGSMIGLENGKIKVHFDGWGPEWDEWLASDSKRMKTLNADEILEREALLRTLEDEGLAGPSSNGSSSVTASTKAATKAITTVPATRTATTAPATRTSTKATPAISSKTSNKKSSVSGSTISAKKPKGDQPKRTSAKRRISPSEQDESAIGQDSEKAPADRTPKRAKKPSKAERLEMLFEQSEDLPLPEPVTPQTVVQASSSTEGSTGTSGKGLTFRSLTKPGVVQDRRLMTPADVRALLDNVHVGMKVQARDKSKQWYESTILQIKSHRLLIQYDGWSDIFNEWMDVGSERLIFPDWKSPNSGEQSRSSSEPRSARAGSAERKRVREIKPKVQRAKSATPLSNVTLPKSPREPSPLTSMAMETSPVIDPAPQQAPQEQQMPQTQAPPTERPTLHISFDDFSSSSDELSDPLSSPTLSEELDDIDDFGDDIKDEGADDGKIDTESLSKPEGEGGEKEATPAPTPYYSLGNPIQLGLEPPEIMEYDYQDEEQAILRIIHRVLDTGLIKNRVVETPPEEPFNQPRATKKKKKPSLSSSQCNEGNVEGGSNREDGGSGDDEDDGDDNHPRTNTKTRDRFVALLEARQQDKGNQSSGISQVARPTVKKDTQELQETRQLAMRNMCSTPLVRFVRQVIYNDADRTAALNNTFESRKAKLVKALSGRKAAKQRHLGPLSKRILGLSNASNILGVTFNEAGYIETPTLLKIKNGLKNMHKITKKKRGRKPLKAMEDPNLSHDENQKDGPGTFQNLRSLTRAKKRNRVLVEDHITFLRRTMVPGTRIRARDRQMDWLIAVIRDVKNSRVLVHYEGYHEYFNEWIDINSERLRYDSTLEQNPPEAAAATAAAAAAMEQSGLEEGAMVFNTDYGGNVDNGDTIHQNGPATNSRQKLDSQGVTPTESEWAPTPATTGVDDVDDSLSSEDGVAQVNCVQCQVKISQFRIYCMYCEAEAKVKESGREPFNLCLWCFSNAFPEQHDHPRSSFATKVIVGPRGVRPVKGGIITRFEKDLLDTEYKETKPDAETLRAAQFQAMMGLEGDQGFVYLDQWKDRKVCAFCNDDGTTKDHFIGPNPFLLASTNRYGGTKKRHFWAHDACARHSPEVIQGKDGTWYNVSMAMRRGRTVKCASCKEKGATIGCFDPKCGRSFHVPCTGKPMSHFEDGVIFWCPQHERDLLQRDAYDETFSCDKCSKVLGVNPWQTCVKCSDDYFHTFDLCQNCFSSDQIYHEHGKEDFKITSLEMIYKEQLEKEAAAQALEQDETAATKKKTVSYKPKMRSLSRMVCSYCWSATSAKWRKGYNGVLMCEDCFLAGPLNEVPMQPPICIEDVTQLQDQIASGLVQPETAGITSRGVGKYATSAEDYSHSPYLTRTAVSSVRFDHSSSQAVYLDSYGPAENQLYSLPIDTTYYDIPGRAPRWATHSGTDYHGTWLPQTVRRAVTKFTNPNEKILSNFLGRGTDAIECFLLGRCCTAVDINPAAITLSIRNCSFAIPPDGTFKAEHRPTILQGDSRKLTGPLFENESFDHVLSHPPYKDCVAYSTHIDGDLSRFGNAAEFQREMNGVIRETYRLLKMGRRCTLGIGDNREHCFYIPVSFQLIRQYINEGFELEELIVKRQRYCAMFGLGTYLCVQFDFLCFTHEFIATLRKIPKEQIDTMILEPDPKLLNDVHITSTTRAIPSCPIERKSVVMGSVWTFKPTEEYDFPTLCVSRMVERFGRNDANWEDYKLSFKVEDSPGPSPSPEEDKTDQWTEHVVDILPPVEEEMVSYERDRLNQIQENNRMLLALGLITELSETSDDIGHQIKIAKDTPCYPPPAPTALRMIAHIPNSVLKSHQVPAYRMAIMHLAIEALEKLPVTGVFVVGTQDIRRPDDGKLIPLSMLVLEDIVRVVGEDCLKLKELIEAVPDGYQKDRRKVTCQAEYEEEICTPADQSITKHLPIVHACYLVFTKVKEKDQGKEGNLEKEDRAENEAEKEDVVEGVDGVENEREKENESMEVAVSSDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZF9</accession>
    <name>A0A9P6SZF9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF1749-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_010876</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000805">
        <property type="protein sequence ID" value="KAG0013756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZF9"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013744">
        <property type="entry name" value="SidJ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31591">
        <property type="entry name" value="UPF0613 PROTEIN PB24D3.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31591:SF1">
        <property type="entry name" value="UPF0613 PROTEIN PB24D3.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08538">
        <property type="entry name" value="DUF1749"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0013756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="301" mass="33033" checksum="40F9E3FD8FCE3627" modified="2023-09-13" version="1">MISLSGTLSVYNPQTRLTMFESGPENSTASVVFIGGLLDGYHALPYLPLLDKTLAEQVGMSLIQVMLSSSHMGYGISSLQEDVKELDVLFDFLLEKRAKTRLFIVGHSTGCQDAISYACYGKHKEAIQGIVLQGPVSDREFMASSMDMYGKYLRLAQRMINDGKGQELMVREVDVAFSGVVRSTNLGGDDDMFSSDIPFEKMQELFGQVKSPLIMVHSAKDEYIPEHINKDKLISQLAAACPTCVGAIVLSDADHAISDQASQATFCDAVVQFLTQVVAHSPDIKISGDFQERMADVRQKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZM9</accession>
    <name>A0A9P6SZM9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_011402</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000911">
        <property type="protein sequence ID" value="KAG0012954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZM9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="122"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0012954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="507" mass="57118" checksum="B07647937FD62989" modified="2023-09-13" version="1" fragment="single">MVANLFNHLVTALDIIPDSTSLDICTNRPSTCVLTGKIRIISKRPFVYKSLTLTAKGTSCVFHRQGPKSMKEKQVFLDVTKDIVYGRSYQRSRRDSLSPLSSPIHGPLETQTDLEPTNETLSNSPHDSSSNNNNSSNGDGNNGPISHQHQSPLPIEQEQQSPVERQASQTDVLSANVQNQVEEGVNDIDFRIEFPSHQNLNSQRFPGILGANPDLCCLPSGPIKTAAGRSSITYILNATLVIGRKYILVNNQMSVSVPFQVQTWQDMIDWNQSEDSSYHGKRRNKIEFQFQVPKQLDLHRLHDLQFGFNARWRTLQDHLKIKEVQYYIVEEEQQESTPVVNTTIISTSATHDCSDYNTPTNSWGHLNSAVRLQIPQPNIVLETTSTPWPHILTISHKLRVLISFDQTLTKERQLQLSFPIRIHPTLSPNGSPVPPELFLGSDSWNRRRLRSSLYGVDARSDNENIDEEDYQLPIYENREDSVLLMVGQEVQEAGLQVDALGASMGMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZN1</accession>
    <name>A0A9P6SZN1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytoplasmic RNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">SGN1_2</name>
        <name evidence="7" type="ORF">BGZ80_010734</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000780">
        <property type="protein sequence ID" value="KAG0013981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZN1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12306">
        <property type="entry name" value="RRM_II_PABPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1390.10:FF:000001">
        <property type="entry name" value="50S ribosomal protein L7/L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.710">
        <property type="entry name" value="Single helix bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00368">
        <property type="entry name" value="Ribosomal_bL12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000206">
        <property type="entry name" value="Ribosomal_bL12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013823">
        <property type="entry name" value="Ribosomal_bL12_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014719">
        <property type="entry name" value="Ribosomal_bL12_C/ClpS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008932">
        <property type="entry name" value="Ribosomal_bL12_oligo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036235">
        <property type="entry name" value="Ribosomal_bL12_oligo_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45987">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45987:SF4">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL12M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00542">
        <property type="entry name" value="Ribosomal_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16320">
        <property type="entry name" value="Ribosomal_L12_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54736">
        <property type="entry name" value="ClpS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48300">
        <property type="entry name" value="Ribosomal protein L7/12, oligomerisation (N-terminal) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="70"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="173"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="179"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0013981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="404" mass="43494" checksum="9A740217304C20ED" modified="2023-09-13" version="1">MSAKDTQDVSHVLSTGNDDLDRDIDDEEIEAMKQRVKEMEAEAAKLREMQAQAEKDMNMTEEDKEAVDSRSVYVGNVDWGSTPEELQAHFQSCGTINRITILCDKWTGQPKGYAYVEFADPSSVANAMVLNESLFRARLIKVTPKRTNIPGMAARGRGRGRGAYRGGFAGHHGYGHHPYGPPPPPFGHPPTYGGYRGRGRGRGRGEVLLDATRPQGKQGAVLSLRTFSARLAPRTISRIAPSVVVNRAANYSSAATEKLDAPGTGKDVDPKIVSIVDQISGLTLLQTTDLVSLLKTRLNIQEIAMPVGGGGGAAPAAQAAAAAPVEEEKAAEKTEFSVKLEKFDAAAKAKLIREIKNIIPGINLVEAKKFVEGAPKVVKENLNKADAEKLKKTLEDLGATVSLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0F4</accession>
    <name>A0A9P6T0F4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_009545</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000582">
        <property type="protein sequence ID" value="KAG0015934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0F4"/>
    <dbReference type="OrthoDB" id="1368at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005254">
        <property type="term" value="F:chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044669">
        <property type="entry name" value="YneE/VCCN1/2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33281">
        <property type="entry name" value="UPF0187 PROTEIN YNEE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33281:SF19">
        <property type="entry name" value="VOLTAGE-DEPENDENT ANION CHANNEL-FORMING PROTEIN YNEE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25539">
        <property type="entry name" value="Bestrophin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="55"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="284"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="312"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="173"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="177"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0015934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="458" mass="51517" checksum="715AB5A37443B7F9" modified="2023-09-13" version="1">MRVYGTTVFVSRRRPLMLRLKGTVILQIWWQVLLVGIYASLVFLINKYSTWKMTYTLNLVSVMGMVVSLLLVFRTNTAYDRYWEGRRLWSQMTLSIRNMTRGIWVCVSETETRDLLEKKSAINLLVAFAFATKHYLRGEYGYNYSDMVDLLTHIPKYSIPTSTQPMDWRMDVPTPLETLSPTPQQQQKSQVSDMYSTSVAERTSGVFSRNRARRASKQQELAFDFLTPTNIPVELSFYIASYIKSCSNKGKVDASTLTMMNNALVMMVDCLTGFERILRTPIPLAYSIHLHHATWIYILALPFQLVANMGPAMIPATMLAAFTMLGILGIGYEIENPFNDDYNDLPLDDFCKVIQAEVDSMVATRAPVPSDWIFSADNYPLSQSDLSAKQLSELSLEQVHEIMASKAPAEGVGARRSVQLQYTRSVTANNIAPADVTSVAGSGLTQVSSTLSSAQEKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0Z6</accession>
    <name>A0A9P6T0Z6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Glutamate decarboxylase</fullName>
            <ecNumber evidence="3 9">4.1.1.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_008542</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6 9">
            <text>L-glutamate + H(+) = 4-aminobutanoate + CO2</text>
            <dbReference type="Rhea" id="RHEA:17785"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:59888"/>
            <dbReference type="EC" id="4.1.1.15"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7 8">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the group II decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.15" evidence="3 9"/>
    <dbReference type="EMBL" id="JAAAID010000466">
        <property type="protein sequence ID" value="KAG0017188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0Z6"/>
    <dbReference type="OrthoDB" id="5152799at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004351">
        <property type="term" value="F:glutamate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006538">
        <property type="term" value="P:L-glutamate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000017">
        <property type="entry name" value="Glutamate decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010107">
        <property type="entry name" value="Glutamate_decarboxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01788">
        <property type="entry name" value="Glu-decarb-GAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43321">
        <property type="entry name" value="GLUTAMATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43321:SF3">
        <property type="entry name" value="GLUTAMATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="5 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 7 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7">
        <location>
            <position position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602129-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0017188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="475" mass="52961" checksum="B959958C6F882A86" modified="2023-09-13" version="1">MPELPTGAQAAYQLIHDELETDGRPSMNLASFVHTWMEPEADKLIMESINKNLADNDEYPATMRIHARCVSIIGNLWKSKGAVGTATIGSSEAVMLGGLAMKKRWQAKRKAEGKDTSNPNIIMGANAQVALEKFARYFDVECRLIPVSKESHHCLDIKKAAEAVDENTIGVYVILGSTYTGHFEDVEGMSNLLDKIQEEKGWDVPIHVDAASGGFVAPFAFPDLKWSFELPRVRSINSSGHKFGLAYAGVGWILWRGEEFLPKELVFTLTYLGAEEQTYTLNFSRPSCFMIAQYYNFIRLGRSGYTSVIQNSLENARILSFALEDTGYFDLISDTHRSKGVFGYENRTSSTEGIKEFNPALPVVAFKLTDKFMKENPHVKQASITALLRSRNWIIPNYALPPNEDNIEILRVVVRESFSQDLIDILITDIIWATETLAASDSGFDVEILTKRTKDPIAAAHSLEHSAGTPYGRQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1X7</accession>
    <name>A0A9P6T1X7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">ATP-dependent RNA helicase mtr4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">MTR4</name>
        <name evidence="12" type="ORF">BGZ80_007754</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the helicase family. SKI2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000402">
        <property type="protein sequence ID" value="KAG0017938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1X7"/>
    <dbReference type="OrthoDB" id="64767at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000460">
        <property type="term" value="P:maturation of 5.8S rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18024">
        <property type="entry name" value="DEXHc_Mtr4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13154">
        <property type="entry name" value="KOW_Mtr4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18795">
        <property type="entry name" value="SF2_C_Ski2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000083">
        <property type="entry name" value="ATP-dependent RNA helicase DOB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000141">
        <property type="entry name" value="ATP-dependent RNA helicase DOB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.300:FF:000001">
        <property type="entry name" value="Mtr4 exosome RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3380.30:FF:000002">
        <property type="entry name" value="superkiller viralicidic activity 2-like 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3380.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025696">
        <property type="entry name" value="Beta-barrel_MTR4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048392">
        <property type="entry name" value="MTR4-like_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050699">
        <property type="entry name" value="RNA-DNA_Helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016438">
        <property type="entry name" value="SKI2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012961">
        <property type="entry name" value="Ski2/MTR4_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131">
        <property type="entry name" value="ATP-DEPENDENT RNA AND DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131:SF7">
        <property type="entry name" value="EXOSOME RNA HELICASE MTR4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08148">
        <property type="entry name" value="DSHCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21408">
        <property type="entry name" value="MTR4-like_stalk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13234">
        <property type="entry name" value="MTR4_beta-barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005198">
        <property type="entry name" value="Antiviral_helicase_SKI2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01142">
        <property type="entry name" value="DSHCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="163"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="399"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="369"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="62"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="82"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="374"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0017938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1079" mass="120960" checksum="253D505DBF087957" modified="2023-09-13" version="1">MFSGGSDAFDVFDESHVEDFSTYNAAEVSRPRKRKDNSDSSNGKEKKHAPSHASALTKDADMDMADMADPEDENFPTEKGAKSNQPMPTVTDSFEQDLEREVASAAGLMPSAEGANVVLSHQVRHQVALPPNWNYVPISQHIPEDPPVRSYPFTLDPFQKLSTYSIERGESVLVSAHTSAGKTVVAEFAIATALRGKQRVIYTSPIKALSNQKYRELLEEFGDVGLMTGDVTINPSASCLVMTTEILRSMLYRGSEVMREVAWVIFDEIHYMRDAERGVVWEETIILLPPKCHYVFLSATIPNAMEFAEWICRNKEQPCHVVYTDFRPTPLQHYLFPQGGEGIHLVVDEKGNFREDNFQKALGALTDSQGVAADDPRGRGGKKDAKKKGKKGGTSGPSDIYKIIKMILVKNYHPVIVFSFSKRECEALALQMSKLDFNDDKESEMVNQVFTNAISSLSEDDRTLPQIEHILPLLRRGIGIHHAGLLPILKEVIEILFQEGLVKVLFATETFSIGLNMPAKTVVFTSVRKWDGKETRWVSGGEYIQMSGRAGRRGLDERGIVIMMLDEKMEPAVAKGMVKGTTDPLNSAFHLSYNMILNLTRVEGISPEYMLERCFYQFQNNANIPQLEKELAQLEASKSAIVFEDEESLVSYHDIRQQLTSLKKDVRDVINHPTHSLPYMQSGRVVKVRYENEDFGWGIVSGYTKKMPSITRGAPPPTNLEPTFILDVLLYCAPKTTVVPGLDGLAPGIKACPPGEKGELMVVPILLSCLEAIATPRIFLLKDLRSSDARHTVHKSLLELQRRFPDGIPLLDPIENMNIKDEAFKKVIRKIEVLESALNTHPLLQTMTQSELQEVYRRYLEKVEITNKIKSVKKQIVEANAIAQLDELKCRKRVLRRLGFTSNSDVIEMKGRVACEITSGDELLLTEMIFNGAFNDLTVEQTVALLSCFVFQEKAEGNSGLREELATPLRLMQEAARKIAKTSQDCKLSLDEEEYVQSFRSELMDVVYAWANGARFSQICKLTDVFEGSIIRAFRRLEELLRQMSAAAKSIGNTELESKFAAGIVCIKRDIIFANSLYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1Y9</accession>
    <name>A0A9P6T1Y9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_006508</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000321">
        <property type="protein sequence ID" value="KAG0018960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1Y9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000624">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050117">
        <property type="entry name" value="MAPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24055">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="33"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="223"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="337"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="446"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="343"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="454"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0018960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="481" mass="54776" checksum="E0447EABFFC0A2D3" modified="2023-09-13" version="1" fragment="single">MPLNECNNNGATTTTSSNNTIQSLLTARNMDQFEVLDELGKGSFGSVFKARHKVTGEMALEALRSGPNIVRLHHFFLEKKELHMVFELMEGNLYQLIKDRNGLKLEESRVKSMVFQVLRGLQHMHAKGIMHRDMKPENLLVTGDIVRIADLGLARDLKSRPPYTTYVSTRWYRSPEVVFKSSAYSCAVDVWAAGTIAAELISLKPLFPGNSDMDQVSRISNVLGSPAPRPQPTDAETEASSSAIGGIGGEWKEGVQMAARMGFTFPTMPVRTLRSIIPNASEEAVELITRLLQYDPKSRLTAYQALHSNWFKDMPEAEDLKFLTDVVQQSPDKRRSMFSGFTFKKDGKDKEKEKEKEKEKDKDKEKEKEKEKEKDRDKDKEKVKDRDKEKEKVKDKEKEKEKIKDRKRGLSLSLPNNTEKPPTLATMILRSSESSYRYGFVASQSQLKLQGQEQEQEQEQEQEQEPQDQQLQQSTLHLNSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1Z5</accession>
    <name>A0A9P6T1Z5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000392">
        <property type="protein sequence ID" value="KAG0018060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1Z5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0018060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="150" mass="16514" checksum="E2DFBA5530A9DB8D" modified="2023-09-13" version="1" fragment="single">MILKNIKVKHVIVKGWRDYKEPTSRHSAGVFGFDNGEAFGATPPSNSKTGSGGDKKQDQAKEDIVGESSSTDAANSKEKILQHNKSLIELNEIQDLLYKPIADIEPLALVVELSSIELYAIWLGSVNASLLGDQHMFVYRDQDLACLNKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2P0</accession>
    <name>A0A9P6T2P0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glycosyltransferase 61 catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_005701</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000280">
        <property type="protein sequence ID" value="KAG0019523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2P0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049625">
        <property type="entry name" value="Glyco_transf_61_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007657">
        <property type="entry name" value="Glycosyltransferase_61"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20961">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20961:SF38">
        <property type="entry name" value="PROTEIN O-LINKED-MANNOSE BETA-1,4-N-ACETYLGLUCOSAMINYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04577">
        <property type="entry name" value="Glyco_transf_61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Glycosyltransferase 61 catalytic" evidence="8">
        <location>
            <begin position="382"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0019523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="729" mass="84300" checksum="946F8EF58DBE3A90" modified="2023-09-13" version="1">MENHKPSMLASIMSMIPVVLTSRRNRHYFLVLLLTSMGMLLILSQPKSYEEAPFGFDHASRPITTENNHWRGNTKAREIEIPAATWTCTDDHLSEEEKELPKNRRTRQCVVENLCVDREGIESPHYDLQDWPVDIHKLTKVIYLGGFIRASGVLPKNLPNVNIMSSDLESDNYWRPRVERIWRKKMKAHYVDETLFVHALYSPFHFSHWLYNGMMPLYSTMKRFGGTKDSWTFRAGHFRFDPEDRMGEWEMDHFFRSGKELVLRQVELSTPFQSLPPPDAPICFKRAVIGLGSQCALHYCEKNIPAEVYQMFRDEIAQYYWETPQVWEKHLASMQEHIDQERKAKDVKDNGASPLKCLELIRYYNFEGINSDHSQDKGELPSRFGQRFPDIANPESDYSKGDKRKLVVGIIQREESRRLINDQELLTELVKAGFRVKWISFDHGCGLAETAYLLRDVNVVISPHGNAIGTSIFMPTHDPVPTVISVDTSRYSEDWFVYTSTAIGQRFTTTTCGPSGYKDEDTEKRCPFYRDATGAKKMMDHYKLILGLPPSMIKTDEKKRSMTWEELDLMRKQQQEYVKEHPVAQTLAAEEFEILIGANQPDALVQKYGDDVWSVLGNFWKAIPRYVDVPRMVKAVETLQDDLDREKETGKSSTNSSSKKYAQFMEYIRNGQACHSAYCIPIINRNVVGETSAFGQYSVDNISKWGQQRPESQALRQGLENPKMWELDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T302</accession>
    <name>A0A9P6T302_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="3">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">USP16_2</name>
        <name evidence="16" type="ORF">BGZ80_004698</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 18">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="3"/>
    <dbReference type="EMBL" id="JAAAID010000237">
        <property type="protein sequence ID" value="KAG0020147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T302"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02667">
        <property type="entry name" value="Peptidase_C19K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001607">
        <property type="entry name" value="Znf_UBP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF888">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02148">
        <property type="entry name" value="zf-UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00290">
        <property type="entry name" value="ZnF_UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50271">
        <property type="entry name" value="ZF_UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8 16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="UBP-type" evidence="15">
        <location>
            <begin position="209"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="USP" evidence="14">
        <location>
            <begin position="379"/>
            <end position="988"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="66"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="668"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="904"/>
            <end position="960"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="167"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="66"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="111"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="723"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="734"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="13">
        <location>
            <begin position="923"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="936"/>
            <end position="958"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0020147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="988" mass="107832" checksum="384CFA44DF3E2D64" modified="2023-09-13" version="1">MITPAAATPITAALGKSELGSVSELVGIGPIAEADVVLEVETTIELQEMVEDPVVVEEDVVEENVVEEDVVEEDAVEEDVVEEDVVEDDKDEDDEDEDDEDEEETTLAMPGKKKRANKPKAKAAAPAEAKAGQHPNQNSDDATDSAILEAVMAESAGFASLEDAAISSAIEASLRSAQEHQEELEENLTEDNDILLDTINEAQFGTGTEKCPHVKDAVKPSAFRKAICQIKDWDHCQGCLGEHARIKKMPFAFEALNLNNSLNELTESLPADALWMCVSCSEINCGRTLRKHAVTHHDTKHDHPLAINLASLDCWCYQCDDQLVTSNNKNPGAQECQSILSKTLQARQAKMRAASVALAKKSKKVAATPTSTKAKIFTPGLQNLGNTCFFNSVMQVLAETKSLKVILTDKSQPNFARSPSASTESGLGPLTTTFKDTLFTMWKHQGGVVTPRDLFTQIAKRWKVFRGFREQDSHELMRHLLDGIRLEEMDVIKKKLAEEDNPASSSSEITIVSNGHDNAPPKYVPFIDNCFSGELVSVIVCQACKKCSYAYENYLDLSLPVKGTPEVGDGSLRDVLRARSKAAGLDIVISTDPGDDPNPIAEEDQGSEAHLKHVEKLLKHVPSRSGPGVLSIERSLSQFTSVDVLDGQNKFACENCYKLVKSYGYSTRDSTSVEKKAPEEVATNNQQTDMEGIVDEVKPEPEGEDEDGSKGSTSEPDLDGESLEVKETKGKSGDAGSSASKPSQESKYLLRKAYKRYLVSSLPQTLVLHLKRFEQSTSRFGLMRKIEDHVDIPFEIDMSPYCIPASDLVEEGAEEFDQDGKVKAPAVAASWNDEKTSKKYRLYGATVHQGSLASGHYTNYVLSSKVELPPPVVSNDKPSSLYPSISTPNGADLPDMSLADILAQQNQKKSGKKKGKKAVAPPAVAPPSVPTPAPEAKPEGDKAASVESEAKESEDSRQWIHCSDTNVRLASLQEVLASRPYLLYYERY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T359</accession>
    <name>A0A9P6T359_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ESCRT-III subunit protein did4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">DID4</name>
        <name evidence="3" type="ORF">BGZ80_002935</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000175">
        <property type="protein sequence ID" value="KAG0021173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T359"/>
    <dbReference type="OrthoDB" id="10252926at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007034">
        <property type="term" value="P:vacuolar transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005024">
        <property type="entry name" value="Snf7_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10476">
        <property type="entry name" value="CHARGED MULTIVESICULAR BODY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03357">
        <property type="entry name" value="Snf7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="182"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="15"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0021173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="221" mass="24932" checksum="3640381BE9F045CF" modified="2023-09-13" version="1">MLNYLFGRKSPAEALRAHQRALSKAQRELDRERIKLEQQEKKLIQDIKKTAKAGQMNAAKVMAKDLVRTRRYIQKFYQMKTQLQAVGLRIQGLRSNQQMAEAMKGATKAMGAMNRNMNLPQIQKIMMEFEKESEIMDMKEEMMADSIDEAVGEEEDEEEEEAIVNQVLDEIGISLDATLASAPGTSIRTPGNAAKERVAQAEGMSADDAALQARLDNLRRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3D3</accession>
    <name>A0A9P6T3D3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ABC transmembrane type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BGZ80_000819</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000118">
        <property type="protein sequence ID" value="KAG0022188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3D3"/>
    <dbReference type="OrthoDB" id="2437870at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18595">
        <property type="entry name" value="ABC_6TM_MRP1_2_3_6_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000020">
        <property type="entry name" value="ABC metal ion transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056227">
        <property type="entry name" value="TMD0_ABC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF443">
        <property type="entry name" value="MULTIDRUG-RESISTANCE LIKE PROTEIN 1, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24357">
        <property type="entry name" value="TMD0_ABC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <keyword evidence="3" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="70"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="160"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="386"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="413"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="272"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="516"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0022188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="516" mass="58542" checksum="B984AD30D61E7B9D" modified="2023-09-13" version="1" fragment="single">MSIWQCQQKDSLGPFNPDCPADFTPCFEDSVLRLIPVLFLILTGVPRLVRLSKQSSLVHPSKNWRQVLKLLGIVALISTTVVIQVLRWNFDPSASLESLSAVIEITSLIFALALTTIENKKSFLSSNVLLVFWLLLTINTGVKLRTLVMGCPASDSTDSYLYGAKLALAVFIFSLETLRKDAGIRLGEDDYQKCPEDEANIFSIASFHWVTGLMRKGYAKPLTFDDLWVLRNEDQSKNVSIAFADAWEKELKKEHPSLVRAISTAYGKPFYIAGIWKAANDILGFLQPVLLREMLRFVMSYKADNPQPLYRGYTIACLMLVCSLSQTTVLHQYFHLCFRTGMHIRAGLVTAIYQKSLRLSNSARQTFTVGEIVNHMSIDAQRVQDLVTYLHVVWSGLFQIVIAMYLLYDTMSWAIFAGVTVMTLMIPLNARLSVFMKDFQKEQMKNKDTRIKLMNELLNGIRVIKLYAWEGTFLQKVLTVRNDYELETMKKIGYLSAVQSFTWACTPFLVSLATFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3F1</accession>
    <name>A0A9P6T3F1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Peptidase M20 dimerisation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_001157</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M20A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000126">
        <property type="protein sequence ID" value="KAG0022052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3F1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050072">
        <property type="entry name" value="Peptidase_M20A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43808">
        <property type="entry name" value="ACETYLORNITHINE DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43808:SF8">
        <property type="entry name" value="PEPTIDASE M20 DIMERISATION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="Bacterial exopeptidase dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M20 dimerisation" evidence="6">
        <location>
            <begin position="165"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0022052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="352" mass="38615" checksum="D77149206EFA0ADD" modified="2023-09-13" version="1">MATKESAQELLDFHKGLVSISCITENESPCTKFLHEHLTKLGYIVELQEIAPGRENVLAYLGKGRNPTVLFNTHIDVVPPYIEYREDEENVYGRGASDAKGCMAAQVQAVEELRKEGKVKEGDVGFLFVVGEEVDHIGMVKANDLGLSPEYLVVGEPTESRLALGHKGVLRLNISIEGKAAHSGYPELGISANEKMIDILYKLKSLKLPKDDYFGQTTMNIGVLKGGLAANIVPAFATVGISFRIATSTKEVLDLVDQVIPAEMQAKDKITIEKITCWEPVRCHSVPGFETFVANYFTDIPSFTSAKHSLLYGPGSILCAHAPHEYINKKELIAAVGSYKDITLKLLAEHDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T486</accession>
    <name>A0A9P6T486_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_009271</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000054">
        <property type="protein sequence ID" value="KAG0023496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T486"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0023496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="341" mass="39444" checksum="0428FC6C9FD7DC16" modified="2023-09-13" version="1">MEYEDQRTNCNIDDEVQQDQQTKVKDEAQYADGNLDDEENYPTSVGDPSVPQQVIVPKDDPQAIVNREAKRRRLLKAVLPQDNDLEESVDSVHDWKIEYEDKSISLLSERFIDISQELYPQHVNDVKSNSLFSDEAQKKYVKVTSQIDAMWNQEWQTVEHPQYFALQTFAGMMIVNEKNCICVQVAEFYNRQENIDKHRELSNISDSSYPTESKRQIFIFSVAKDLYSQHKPKIPVDVILKLKDIITVLAPDNEYLSQNQKKLVYNEIQAQQSLMTLKGLGFQASYQFLSNALEAPDADALETILWNYPQSSDLDILEKQLIKIIRYVLTDFSNKCSRPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MC91</accession>
    <name>A0A9P6MC91_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_009070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010005161">
        <property type="protein sequence ID" value="KAF9991521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MC91"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9991521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="150" mass="16643" checksum="AC784983A256D805" modified="2023-09-13" version="1" fragment="single">MEIGTGARHAIHEPSKAAMLKTPRVDQTLLPEEQATYPRGDCNGHENPARPEKIFNIMEIGAGARHVIHKHELSNAVMLKVPRVDQTLLPEEQATYPHGGCDEHENPARPEKVFSIMEIGSGVRHAVHEPSKAAMLKTPRVDQTLLPEEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MCD5</accession>
    <name>A0A9P6MCD5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AMP-dependent synthetase/ligase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_009081</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010005175">
        <property type="protein sequence ID" value="KAF9991505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MCD5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043041">
        <property type="term" value="P:amino acid activation for nonribosomal peptide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.980">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020459">
        <property type="entry name" value="AMP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF1">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00154">
        <property type="entry name" value="AMPBINDING"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9991505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="136" mass="14351" checksum="45D38D8E6EC80671" modified="2023-09-13" version="1" fragment="single">MIIGLLAIMKAGSAYVPLDPLHASDRLRSILDDAAPTILVADKVGSMAIGDVGLSTRVVVDPNTLGQSAINNPQITELTSRHLAYVIYTSGSTGKPKGVMIEHQGVVNIIQSQQSALNLSSSTRMTQFLSISFDAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MDZ9</accession>
    <name>A0A9P6MDZ9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008042</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004244">
        <property type="protein sequence ID" value="KAF9993759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MDZ9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="347"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="183"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="230"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9993759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="378" mass="41150" checksum="46D500CEEAE362F1" modified="2023-09-13" version="1" fragment="single">TKIGGSLGKSNPAGYPLASQKQKRRQSESNKFEKRTSDSDFQDTAAALEDLEKEIGALKSKEIALPTGDDILLVSDTSSPTQYYDSEQTRYALRAFLLGGNREFEEMIEYGFPSDLFPDSDSKSRTATASDPLPEMNCHYLTLRITLTPWHARADESKLYGPVTDATENQTQLKTMVNKFFTRTPGAATGSSSGTSTPVSMSSPPPSQRARMLGGSRRPSEQSVTTRSNRSSAEHTTSTESARATPISHPDSERETVDLSRTSIRSDDRSPERYGSGRARSRTDASAYPISTKPTTRFPAAAGNNSGRSALLPPSSMRTQSPLPRKGSLSVLSVPIKYSQELRPQTFHDRGLMGNNGTVIPPFRRDGSSPAIFSNPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MEE2</accession>
    <name>A0A9P6MEE2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_007814</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004074">
        <property type="protein sequence ID" value="KAF9994414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MEE2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9994414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="386" mass="41461" checksum="E7BFCBD81E701506" modified="2023-09-13" version="1" fragment="single">NISRVEALGNMELASHSISHSPNLNDFPIGTGKEIWDGTKYDEDNYFPFIGECVNTNGVWNTTVPGATPCTPLGAYNFFTTQGTLYGETRVSKFILESISIVNATVRSFRTGHLLFPTAFPQILESVGFKYSSSSAANDQNTHMPFQPFYNSAYNQEVDLIEFPLSASDEDGEMNGDFYAPGTGGYVNGSYAWNQYQCIQKQAKYGTQYTFLIHPTTHAVPGLAPSTFENKLAFQQTLTPLVTNVSYFDTMGGRGDFHKARINAGIDVSISGSTATVTVTLQQKITDLTLRVPTAWTFKSSTVAVNTAAAGAVTLMNVVPAGTVTLKFQTSGTVTTTINPSAGPAATTTTISMASPTVPAPTPTPTNPLMVDDFVDPSRYSSSSNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MGA9</accession>
    <name>A0A9P6MGA9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">HMG box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_006651</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003294">
        <property type="protein sequence ID" value="KAF9999034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MGA9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22016">
        <property type="entry name" value="HMG-box_NHP10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051965">
        <property type="entry name" value="ChromReg_NeuronalGeneExpr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056513">
        <property type="entry name" value="INO80F"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46040">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46040:SF3">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24245">
        <property type="entry name" value="INO80F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="7">
        <location>
            <begin position="199"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="4">
        <location>
            <begin position="199"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="54"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="274"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="371"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="10"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="100"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="121"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="170"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="314"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="343"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="371"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="392"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="443"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9999034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="465" mass="51438" checksum="6F20C517AAF0EEED" modified="2023-09-13" version="1" fragment="single">IKYKRKYKDLKKRIRDIEELETDNDILNIKLSRARKNIHRLRVERSFLFDRLDHSENAAHPSTSSSSTSDSDTDDERNEGDGDGSKSHRNQHRHGVDRLKRFRHSYSHSGHHGRHDSSHSQSLPASSGTTLSNHHNARSKTPPSRASSVPRGSAHHSASSSLGQIIDPSQAPSLSPSSVGTGKRANAVQKKRRKDPLAPKRPSNAFFIFSQQHRQQARDEKKEGNQSELTKFLGQQWKSMPPTEKKIYSDLASQDRKRYQEEMILYEHEHGQGNTGLLDFSQKQPKKAPGKVGRPSKYDKYSAELKALNGTSGGDNDNTNNSISSNSSNNGENNNINGTDNNLLATTSNGHGSSVTKKMEILSMMNEDTEVEGEDMMASHDEEEDARMGDGGSEEDHDEDGEDDDDIDEDPEDDDDDDDEAVKGGGLDATLEGALHKGIAYSRHGEDVDMVEAHRSQGPGLIASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MGZ0</accession>
    <name>A0A9P6MGZ0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_006540</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003232">
        <property type="protein sequence ID" value="KAF9999587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MGZ0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9999587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="151" mass="17246" checksum="AA72E1515E758912" modified="2023-09-13" version="1" fragment="single">GLSNHVFVGASSGNTRLSLWTALSVITIVVFIQISPFIYGISIAPERYEAVEQWIYRKPTQRPSRVAALEHNRSPNATIDSGIPNISLFFSQPIKLRKPVAHEITPVLEMHYPNKDEILPRDDIFMTPSQRPPQLWDVNEQKGRPDPYQRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MHL5</accession>
    <name>A0A9P6MHL5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006426</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003173">
        <property type="protein sequence ID" value="KAG0000105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MHL5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0000105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="104" mass="10632" checksum="F878C74F9BB2399F" modified="2023-09-13" version="1" fragment="single">MLPHQNLSEKNRGVDSVDGKCNEGPPQAQSAIVRGLRSDVAANVETTNDQPLLLGNGSTGKSPSKSAIGFNGDSSIHVSDSLGSSQAGNNNNSCILLSKVAGNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MHX7</accession>
    <name>A0A9P6MHX7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rhodanese domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_006035</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002981">
        <property type="protein sequence ID" value="KAG0002056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MHX7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="2">
        <location>
            <begin position="2"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="31"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="48"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0002056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="120" mass="12420" checksum="A49F6520EB7BDA6C" modified="2023-09-13" version="1" fragment="single">FASALVRHGFPRVALLMGGIDALRISDAPSTSLTSTTAAPGTAPPASPSLSGTNTSTPTPTSTTTTTAAAATAANSMITICSCRVIRQNITVQARVKDDVFVHKCKTPFTQKRIRSTITS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MIH8</accession>
    <name>A0A9P6MIH8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AIG1-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_005837</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002877">
        <property type="protein sequence ID" value="KAG0003171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MIH8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0003171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="259" mass="29627" checksum="454FED9112E6B31A" modified="2023-09-13" version="1" fragment="single">MTEPDPVAIKVESLLQGNSDFNDFEDTINERNNLQIIRTTSSNSLTQYQFNMIDTPGLNDTHGEDEAHIARIFETLKAAGNIHLILITVGLGPFTDSLRKAIKCYFDMFPEFQSLVVFVHTSSDYKNLHSSQKKAHSELLTKKKTLHEIIGRDSCKHFEIDCDLDTNKPFKISITYNTIRNILCMAPFNQPVAMNRIMMRKTAKMKNVDNTLIDKYKAIVATRQTTLEFKNEAQAIVMDKLLKLEIQINDLRSEVSDHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MIU8</accession>
    <name>A0A9P6MIU8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">General transcription repressor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">TUP1_1</name>
        <name evidence="5" type="ORF">BGZ80_006039</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002985">
        <property type="protein sequence ID" value="KAG0002011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MIU8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879:SF9">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="61"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="96"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="143"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="185"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0002011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="255" mass="28164" checksum="9081AE55AD8394A2" modified="2023-09-13" version="1">MSANWSDDPDNVPPQLKREGPDWFAISNPEVPQLLKVDLVHSMDHSSVLADDTAVKDDLYIRSVCFSPDGKYLATGAEDKQIRIWEIGRKKIRMILKGHEQDIYSLDFSRDGRIIVSGSGDQTARIWDMENGKCLYVLAVGDADLKDAGVTSVAISPDGRLVAAGSLDRMVRVWDTHNGQLLEKLEGHKDSVYSVAFAPDGKTLVSGSLDRTLKSWELNLSGRPGQNGARGSICKATYSGHKVLKTLDMRMMINF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MJD6</accession>
    <name>A0A9P6MJD6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_005613</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002762">
        <property type="protein sequence ID" value="KAG0004494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MJD6"/>
    <dbReference type="OrthoDB" id="76265at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031543">
        <property type="term" value="F:peptidyl-proline dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071456">
        <property type="term" value="P:cellular response to hypoxia"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051559">
        <property type="entry name" value="HIF_prolyl_hydroxylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12907">
        <property type="entry name" value="EGL NINE HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12907:SF26">
        <property type="entry name" value="HIF PROLYL HYDROXYLASE, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0847">Vitamin C</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="7">
        <location>
            <begin position="195"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0004494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="297" mass="33680" checksum="250B4806C34079DB" modified="2023-09-13" version="1" fragment="single">MEPTDSHEDALAERIMKYASSKGNSLPPFPGDDVESIPSDYEYEEGEEEVEEVEEISEMDLLQHLDESMPPILLAQELFNDDVDSKSFKVLTADNANELFHKGYTILENVIDLSVIQAVREWGTEMFKTGKMDKASGKHSEEEDPFREGNARGDYTIWVSPGSKFLEQSSALNHCVDWFSKQLHEDLIKLVHLHGLAEYQLAYYPPDSSHYERHRDSFPTNDREDRDQRRVTAIVYFNPEWAQGDGGELRIFDKGMGGEEEKQIDIAPKAGRCVLFLSGVMDHAVLPSFSGRIALTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MLP5</accession>
    <name>A0A9P6MLP5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_005140</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002551">
        <property type="protein sequence ID" value="KAG0006788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MLP5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="817"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="596"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="617"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="838"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0006788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="838" mass="92009" checksum="B0E57D08F6CFC04B" modified="2023-09-13" version="1" fragment="single">TPEIEAPLPQAQPNHAPLQREDCSKGSSEIQHVEKEDVNTNSLPPLLPHAARRRPRSKGMRSSAINRSRSLSPLGGDVSELDYQGIKAGEANGNALRRSTPFQLLLVNRRLANIVVQLLWGATVFHGHDVSLMESLISTLNKDDSFDSSSESANSSPGIFQELAYMYQGKGTTSKLCTTTDALCREGITPYMGSSFTMQRGSTRTTQKASQSYINKTECYQASRPSERIGVHQRDQKGSENYITSIKGGSASLRDANSCRKHPNMRVGTFSRRSHCVAEPLCRCVGKDTALWSYRQLVKRVVLNFAHPQASPQLLVRALECISSRCRNQIQALDLHANEKMQAAGLETSSELERLFGSGFSKLRYLRLQGGLVDNQLFSALIKGLSTPPMTPCRLSQVFLGPGSVTDSAIDKLIAVTGHSLEVFAVTSCVDVSGGALANLLTRCPKLRVLSVHRSIAKDKELLEGLGIELEDGLSLPSTPSALSAPSPDTSSRKPIIAPLERLELGTVKLTEVGVAEIVKGTCLTLRFLVLEMQHFKDDFLKCAIAPLCRLEGLYFVEPDLVPQQSRQQQVMQDPVQEEQRPRRWFFDFRRGRRTLETQQQQQQHHHQPQHRGLQSSDRHTPEHHGHPSHSLSSSGPAPRQSPWLGETSTNEWVQYGNCALWATSAVGSSVSPRIGGNRDTSTENLLISQSRARSFTAYFRAISRRLVSMLSSNGNNAALDSNPLAGLENPADVTTDPLSSAVVENEYESLLERFGVDPKTIEAVLLNLQPSLKVFTAMEADVIQAALEVPEETAITSSSDMALNYDVVQRDRLETFLRLIVLLGALVFGAAMSVSVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MLW1</accession>
    <name>A0A9P6MLW1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Abc metal ion transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BGZ80_005031</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002501">
        <property type="protein sequence ID" value="KAG0007117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MLW1"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18595">
        <property type="entry name" value="ABC_6TM_MRP1_2_3_6_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18603">
        <property type="entry name" value="ABC_6TM_MRP1_2_3_6_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000020">
        <property type="entry name" value="ABC metal ion transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000001">
        <property type="entry name" value="ATP-binding cassette subfamily C member 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000997">
        <property type="entry name" value="Multidrug resistance-associated protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000074">
        <property type="entry name" value="Multidrug resistance-associated protein 5 isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF443">
        <property type="entry name" value="MULTIDRUG-RESISTANCE LIKE PROTEIN 1, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="4" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="163"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="190"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="271"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="307"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="758"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="841"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="14">
        <location>
            <begin position="49"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="13">
        <location>
            <begin position="374"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="14">
        <location>
            <begin position="718"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="13">
        <location>
            <begin position="1039"/>
            <end position="1273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="640"/>
            <end position="668"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0007117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="17">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1278" mass="142867" checksum="1E4DD8EB547D754D" modified="2023-09-13" version="1">MDDLWGLRKEDQSKTVSDTFAASWDRELKKKHPSLLKALARAFGKPFYIAGIWKAANDILGFLQPVLLREMLQFVMSYKTETPQPLYRGYAIACLMFVCSVSQTTVLHQYFHLCFRTGMHIRAGLVTAIYQKSLRLSNSARQDFTVGEIVNHMSIDAQRLQDLVSYLHVVWSGLFQITIALYLLYDTMSWAIFAGVAIMILAIPLNAKLSVFMKNFQKQQMKNKDTRIKLMNELLNGIRVIKLYAWEGTFLQKVLTIRNDHELAMMKKIGYLSAIQSFTWACTPFLVSLSTFTVYALVLKRPMTTDIVFPSIALFNLLQFPLAMFPNVISSSVEAYVALGRVHKFLTSAEVDPTAIIVEARSSSRQTASDKYAILVTSASYSWYKNSPAVISDINLALKKDCLLSVIGRVGSGKSSLIAALCGDLERVSGEIRVRGSVAFVPQQAWIMNDTLRANILFGNAYDPVYYQKTIEACCLQQDIAMLLGGDMTEIGERGINLSGGQKARISLARAVYARADIYLLDDPLSAVDAHVGKSIFENVIGPTGLLAGKTRVFVTHQIQYLAHSTSILMLRDGRMVEQGDFQGLMAKKADVYQLMTEFGHGTARHSQLNSSGEIEPYVVQNTPLEEDVVETDAFPAEEASLLSSTPRSARRNSIRSTTSVRTLRRPSVASALQRTTAKVEPPVNSTNIILEEQMKQGSVNKSVYLAYAKACSYSAVIAYLLSMILSQTASISTSLWLTHWSSDNDRGEGVSSPMFYVGIYAALGFSFSILTVFQSIILQVYCGVRSARVLHQEMLHSVLRSPMMFFDTTPMGRILNRFSKDQSTIDEVLPRSFAGYSRTLFQVASVLVVVTMSTPSFIFVIFPFSFVYLWLQRYFLATSREIRRLDSVSRSPVFAHFQETLGGISTIRAYRQQDRFIHGNEHRLDQNLRAFYPSIAGNRWLAFRLESLSSIIIFGSATLSVITLARGGSVDPGLVGLSLTYALSITQTLNWMVRQYTEIESNIVSVERLQEYIELKPEAPEIIKGHRPPRNWPADGRVEFVDYETRYRPGLELVLRGVNCSIRPHEKVGICGRTGAGKSSLTLSLFRIIEAARGQIFVDGIDISTLGLYDVRSRFSIIPQDPVLFAGTIRFNLDPLGTKSDAELWQALEDSYLKDYVTTMECGLNAMVLESGDNFSVGQRQLICLARALLRKTSLLILDEATAAIDLETDALVQAIIRQKFSDCTILTIAHRINTVMDSDRIMMLDEGKVVEFDSPQNLLKDENSIFYSLAKQSGNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MM50</accession>
    <name>A0A9P6MM50_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_004549</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002306">
        <property type="protein sequence ID" value="KAG0007541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MM50"/>
    <dbReference type="OrthoDB" id="2424837at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0007541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="126" mass="14277" checksum="148A68B29EC7D87A" modified="2023-09-13" version="1">MKLPASHDFFIGMDYLHLFGMGITGIKNPIEDFDTPTAPIPDVPPLIVSRDRPDIELTPEFIEYRRRFLLPIKSELDTNADIPRNSHCPIPEMKVYLTVPPGTVVYSRPRSFAQADQALVQETVVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MM68</accession>
    <name>A0A9P6MM68_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Retinoblastoma binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">RBBP7</name>
        <name evidence="8" type="ORF">BGZ80_004566</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002313">
        <property type="protein sequence ID" value="KAG0007525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MM68"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022052">
        <property type="entry name" value="Histone-bd_RBBP4-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050459">
        <property type="entry name" value="WD_repeat_RBAP46/RBAP48/MSI1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22850">
        <property type="entry name" value="WD40 REPEAT FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12265">
        <property type="entry name" value="CAF1C_H4-bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 6" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Histone-binding protein RBBP4-like N-terminal" evidence="7">
        <location>
            <begin position="27"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="182"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="232"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="278"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="322"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0007525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="376" mass="42041" checksum="D1902FE2B411E614" modified="2023-09-13" version="1" fragment="single">MARSGSPNEMDGGLEANAVTEEKLINEEYKIWKKNSPFLYDLVVTHALEWPTLTCQWLPDIERPEGKDYTVQRLLIGTHTSDNDQNYLQIAQVQLPSDSTPIDTRKFDDERGEVGGFGGTECKISVTQRINHEGEVNRARYMPQNPDIIATKTVSGDLFIFDRTRHPSQPAPGGICSPEIRLQGHTKEGYGLSWNPTLQGHLISASEDTTVCHWDINAATKDKKVLDAYRIYRGHTAVVEDVAWHALHDSLFASVGDDQRMLIWDTRSTSSDKPVHNIHAHAAEVNCVAFSPSSEFILATGSGDRTVGLWDLRNLKLKLHSFESHQDEILQLAWSPHNETILASAGGDRRINIWDLSRIGEEQTAEDAEDGPPELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MM98</accession>
    <name>A0A9P6MM98_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Fatty acyl-CoA reductase</fullName>
            <ecNumber evidence="1">1.2.1.84</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">FAR1</name>
        <name evidence="3" type="ORF">BGZ80_004882</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a long-chain fatty acyl-CoA + 2 NADPH + 2 H(+) = a long-chain primary fatty alcohol + 2 NADP(+) + CoA</text>
            <dbReference type="Rhea" id="RHEA:52716"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:77396"/>
            <dbReference type="ChEBI" id="CHEBI:83139"/>
            <dbReference type="EC" id="1.2.1.84"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the fatty acyl-CoA reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.84" evidence="1"/>
    <dbReference type="EMBL" id="JAAAID010002442">
        <property type="protein sequence ID" value="KAG0007264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MM98"/>
    <dbReference type="OrthoDB" id="429813at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102965">
        <property type="term" value="F:alcohol-forming long-chain fatty acyl-CoA reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080019">
        <property type="term" value="F:alcohol-forming very long-chain fatty acyl-CoA reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035336">
        <property type="term" value="P:long-chain fatty-acyl-CoA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05236">
        <property type="entry name" value="FAR-N_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026055">
        <property type="entry name" value="FAR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013120">
        <property type="entry name" value="FAR_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11011:SF45">
        <property type="entry name" value="FATTY ACYL-COA REDUCTASE CG8306-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11011">
        <property type="entry name" value="MALE STERILITY PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07993">
        <property type="entry name" value="NAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="1" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioester reductase (TE)" evidence="2">
        <location>
            <begin position="25"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0007264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="499" mass="56734" checksum="DD4B28164BF6DEA0" modified="2023-09-13" version="1">MSPPKYQFRPTKAKEFYNNNTVIFLTGATGFVGKTILEKLLRSFPQITKVYLLVRISGNKTLKGRVENDVFASKIFDTLRAQFSSPEEFQEKIIKKIVPVRGDITFDHLGLSDQDLAMIREDVTVIINSAASVSFDDPLNNALEMNTKGPLRTFEVAQGAKKLSAFVHISTCYVNSPMIGKRIDETIYDHPFGEPEAIYEMLTKMSYEDIRNYERSVVLKKYPNTYTFSKSLTEHLIKKRFKAMDLPIVIVRPSIVTAAKQEPVPGWVEGTAAANKAVVSCALGHVQEWIGIESTKTDLIPVDVVAKVILLSATTADRTLAQPPIYHVGTSCINPITWGLFGIYLAAYWNAVERPRRRISDDIRFDMYPHAEFKRRFDIRFGEQIRTLSQHKDGKKLKLRISKAMAIPMTFKTFSTSEWFFDVSNTLALDDAAPAELKSGLRRGMDWHKYMEDYNAGVQEFILREKVDRSIVIDYSKTSLNKTQLKEKDGREVEITARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMA9</accession>
    <name>A0A9P6MMA9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">60S ribosomal protein L13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RPL13_2</name>
        <name evidence="4" type="ORF">BGZ80_004861</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002430">
        <property type="protein sequence ID" value="KAG0007285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMA9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001380">
        <property type="entry name" value="Ribosomal_eL13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11722">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11722:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01294">
        <property type="entry name" value="Ribosomal_L13e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0007285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="71" mass="8246" checksum="4464D9A7C91CB802" modified="2023-09-13" version="1" fragment="single">MKHNNQLPGEHFRKDWQTRVKTWLDQAGRKKSRRIARISKAARIAPRPVDGLIRPAVRCPTVKYNTKLRAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMD5</accession>
    <name>A0A9P6MMD5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_004322</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002213">
        <property type="protein sequence ID" value="KAG0007722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMD5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="150"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="221"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="301"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="224"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="312"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="341"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0007722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="412" mass="46288" checksum="1DBB2AE68E01566F" modified="2023-09-13" version="1">MPRSWSPPLDVNTRTITSVSVVRAKLEHLDAIHDIQLKAYKDREDFHESPEVFKAKLKSYPAGNFVAIVTSSVVTNDDTSTWVGKDTEKEEEEGSGEGAGVEEVQDDSAMDQDIETTNLTEETHIVRARTPDVVEGDDVEDEGATFLSSSTFKSATTLGVDNPAEYSSQGQQGHARESQLDEDEDDDEDFTTVLFQWDEPVGYLLSHPYSRESMRLHHVGGVGSEAATKTTTATEPSKTKKMRLEAGEETTDTESEEDPFDHDQLMEKYYIHDCAIHPDWRGKGLASRLWKALEESLTPASQNELLNKEGLVDTEEEDEGEEEEEASSSSPSTPAQTQKDHHPHRHRRHRKRSRKAHRRKGAPNLKEIVLVSVQGTRPFWERTAGFQVVTDHDMDLSGYGDEALLMRKSFIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMV5</accession>
    <name>A0A9P6MMV5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_004232</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002180">
        <property type="protein sequence ID" value="KAG0007784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMV5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056251">
        <property type="entry name" value="Arm_rpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055496">
        <property type="entry name" value="DUF7068"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46312">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46312:SF2">
        <property type="entry name" value="NUCLEOTIDE-BINDING OLIGOMERIZATION DOMAIN-CONTAINING PROTEIN 2-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23948">
        <property type="entry name" value="ARM_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23238">
        <property type="entry name" value="DUF7068"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05729">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50837">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NACHT" evidence="2">
        <location>
            <begin position="657"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="96"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0007784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="948" mass="106062" checksum="4C2F5771D27062FE" modified="2023-09-13" version="1" fragment="single">MASIPDTDQHAQSVGARGHSSGSHSETASIYGPATSHGSETNHVITHTETLTEGQKPIRKGDNHGDQGDFDNAAKNYKLAAQFYPNEATEKLKSISLRRTTSESSISTTHSLPDHPRKRKRDKLRALFKLSSRRPTSTGPFFPGNGQSHPLLLMSQATDMPKGLVCPFDDAKDTNDVVVSFIEADDETKNTLRDQIYDIIAQFKDTLATSKTVQELVTLARIPDRDIFVQTIEKLLKITKESSLVPIIVLQGLAVAINSCPDGIDMREMQGIYLDILQPLKQRLETAQSDGNVGQLISLLHALTALINAMVCRNVHALDHEGTFNPLNSMFDGLKGHENPTVRFLALYAKQGLAYVGNDESLGMSIYRRGRLAIAVVVDIADGISNVDLEKFESAYNSIMEISGFTIPAKWYQGLIYVDCILGLQDWSRFERFVLESKLKSDECFLQGICLRLEQVAVTRSVQEIRKGAIEFLHYLSKNPSKQVRQAVTAVLERLVSSGCTKHNETNTKHHAKTIKCACATYQSEYFGPPPVWDPYWYTTSSNILLEAVQRRRQNNKNMASLIEIHAALESYYKSSLVVRRVTGDILDLEICYINLAVVEARGQREKDKRDLKSDAVAFQRIPSRGESTDADIASSMPLENLFDKRKLPNGDEYVPKRVLIHGRAGIGKSTLCKKLVHLHQGGLWRDQFDIALWLQLRQLKSCNCRNIDGLLSEKYFSIQSKSKREALSRTVSAQIDAGRVLFVLNGLDEIVTSIGEEKDDTLEVFLSDLLQKEHIVITTRPSGIDKDILQGIDLELETIGFSPQNVNDYLHIPEVLPPDQIKPVQEFIDRTPVIQGLVNIPIQLDAICFSWGSIPIDGDEEITVTSLYKAMVRKLWRKDTLRLGKSSSGETFNEIHGLDSYEIDELMDAGIEFLGYLAFKGLEDNYCIEFNEGGLPNPERHPRSKES</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MN52</accession>
    <name>A0A9P6MN52_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003492</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001927">
        <property type="protein sequence ID" value="KAG0008399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="241"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="816"/>
            <end position="998"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1029"/>
            <end position="1193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1213"/>
            <end position="1278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1354"/>
            <end position="1375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="199"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="368"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="402"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="429"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="457"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="489"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="528"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="538"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="586"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="647"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="657"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="687"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="703"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="719"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="820"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="831"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="871"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="915"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="944"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="979"/>
            <end position="988"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1044"/>
            <end position="1062"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1077"/>
            <end position="1089"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1108"/>
            <end position="1120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1140"/>
            <end position="1149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1165"/>
            <end position="1192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1237"/>
            <end position="1251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1266"/>
            <end position="1278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1354"/>
            <end position="1366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0008399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1408" mass="152138" checksum="E720107759E01E6E" modified="2023-09-13" version="1">MGGKDTSNHMSNTGQSGTSAMFNADSDETRVEQVFEQFRAKCQYYSKLGERLGSPAGNPNNDVVVPTLIAIYVTAVLEYVAEYVLQIASTIADRQDHADMVTVREVYVALLEDRQIESTFETMILKSQLQKRFRNSLIMPGTGSKPEESTPATVKRSGSWGKQLRLGNADKPKLEVTLPTDIEEDEIFIDPNRPQFGDWDERPDAENKMKKKSDFEMLFSSGETMKVSLTPNRLRTIEVHKKTGGAGGPMATRSSSRAASVLGAKTHARRPSTPGEPATSSRKNSHSIEPNTSSIPPPVPATPSVPAIPANVGVSQPILKKQGQHAVATAEPPHSQSKQQQSSTFQGLGISDNGARKPTPQDTMEGVRSSTSTLDSQITMSTAGPTSPAVTRNGKLPIGSLKGTSQATNELEQLVNSAPKSPFLDSSHTEPPMTPTSETSTKKDNPLKSFMGRLGRNSMQRTSMESNNSNSAGSPTSIRSFTITQHPQSSSGSGSASGSTNGSVNSGYTGQTSVMSTTSTPSPYQMERQGSSQNVYDQQQQQQQQQQQQEQQQQQQVPPPVTGNKALPQDSRPNLSTAGFPLPPDSNKNAKLPSNRNVVSPQPIKAVPSSPNSNVPQFPQPPMSPEASGFPIPSRGASLNHDVASPTKPTSSGSYDTTTTTTTTTTTRTGLEAGLPRPLSPRPVSPRPSSSRSSSPRPHSPLQTPQHFHRNNNTLDGQSTTPGSIISPSPLSNSISGSNISPSSSSTSLITVGKVQHITERFAKTAQSPVHGFKSQDHLQNHPNRISLEGTIRANPFYQQDRNSSVRSSLADLSSISGSATNSGEIQAQHSKSSSSSPALPDSDVDPTPPKRANDGAARTNAPSSDSDSDIDNHQDHENNRGNTIKDGMVSPATSPEMGSFKDRLPSATTRTLTAAAAAAKQQQHQHQQQQQQQQQQMATPPVSENAASSSEQEAGPISPTKKRSSIVSENGAVNRQFHVYDEMKPATEEPPVEEEEEIPYVAVVPRKLATSSSSRHSIFVDEAAQAMDALSRARHRQSMGLEIGEDGLDDEDDEDDEDDDTNGVIAPPEKWHYSDLDEDEDDDDDYEYDGQSRRKHESFMSAKSVLHNGSSVSLANASNDTQDEDEEKENEQQATKESPLNKDLKPSDFVKGNEYVDLVPAVDTQDEDQNGGDEDESEDSEDLEDDDDEEGQDRRIYLQNLRAQQREARRLERLAAGETTNQAKKERKGKIAVDTGSATASAVSESSASGSKKKAPKKGSQQGRPQTPNTPVPTTQIIPLTPTDFVLIRQKLFAAGNFEASMRMLDTIFHAAMAKMIEGRERGVQTEPVSFLDQDLTTESVDQDDQSKEIKATATTVGVSTSTSTDDNEDTQPKKQLQWVAVAPATPVVPEDDDDEDRVVEWLLGGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MN64</accession>
    <name>A0A9P6MN64_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">MFS general substrate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_004610</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002332">
        <property type="protein sequence ID" value="KAG0007484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MN64"/>
    <dbReference type="OrthoDB" id="196103at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051617">
        <property type="entry name" value="UNC-93-like_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23294">
        <property type="entry name" value="ET TRANSLATION PRODUCT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23294:SF59">
        <property type="entry name" value="UNC93-LIKE PROTEIN C922.05C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="48"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="99"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="138"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="171"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="225"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="262"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="292"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="349"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="427"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0007484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="474" mass="52238" checksum="86BF561389AAF033" modified="2023-09-13" version="1">MLKLTDPLTQVIILGFVCFCIPGMFNSLSGSGSYGLDPKESDVGNNAGTTYSIVFAFSSLFAGTLFNIFGHRLLLVIGGLTYVLYIGSFLAYHHIQSMTFIWISSICLGLGAGWLWTAQGAIMMGYPEENDKGKYFSIFWGIFNLGAVIGNFIPVGLAWNDPTASGASDGAYIAYMVIMVVGSFLSLLLLPASKIFRKDGSSVTVIKYSSPITELKSVFALFKDWRMLALFPMSFASNWFYTYQFTYNSLNFTVRTRSLNSAIYWLAQIFASVLFGAFLDRHKWSRTTRARYGIILLTAVLIAVWIGGLINQTTFGPRGYITDATGTAIKDPADYHMIDATTKAYVGPFFLYFFYGVSDAMYQGYAYWLLGALTNDPTVAGRYAGFYKFAQNIGSCIAPWVQMSAIGIAPHEGYNTIHSRGRGMYEAVICVILVFLGIVGAFPVAFKAVKEHTVDEVDNVVSEKQEAGFEDAKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNB9</accession>
    <name>A0A9P6MNB9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_003324</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001872">
        <property type="protein sequence ID" value="KAG0008546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNB9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.80">
        <property type="entry name" value="E3 ubiquitin-protein ligase SopA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056251">
        <property type="entry name" value="Arm_rpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23948">
        <property type="entry name" value="ARM_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05729">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141571">
        <property type="entry name" value="Pentapeptide repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arm-like repeat" evidence="3">
        <location>
            <begin position="214"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="domain" description="NACHT" evidence="2">
        <location>
            <begin position="679"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1011"/>
            <end position="1030"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1011"/>
            <end position="1029"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0008546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1215" mass="138767" checksum="3466F4352DC8D981" modified="2023-09-13" version="1" fragment="single">MFRNPFSSPTSKLSLEDVLELANKYMENAREDSDPRKALKLTNNAKSLMKDAEKIYIAKKVKDPILGDGIANSYHELRKLFDKLGCHDKAQESHGKAVKWGYVCVVSQYDDTLQPAEMNKSAHQLPSPPADAQDVTLIKVNSYVSVPKEDVGQIPRNHFEQNIAPPVAEYTLPDIGERFNKTTQLAYCLSLLNPSLISKEQLDKNEFDWVQARVDDPDEKNRLQTMATDLIRAFVRDELKNLDVVAEVVTLAPVLDQDDFVKLLQVFVNEVNRSILLKTHLLGGLAQLIRNAPQGYIDEDDLVKILDLLNTRLKDTHKQSTQHIYRLAQTISRVLDSMVDSQVEGLSRELLREPLSDYLKELQKSSDPYLVYQTAYAYQALLYVSNDESILQSMMRRTGKVVQGISGVISAVKALNVVDLIEDLQSIQDGLVGVENVIQLVSDTYEDTKRLAEGGEELIESLKEGFNFTRKSSWYPALRGLDSLLQEGRFIEFEKLIREAPCWHNPTFQWGVCQRLGEISSNPFWDLNTRKSAVAFLVDLYNDDLRWGCQPYIKQWILDILNQLTQSTQDIITDDTQRLLQELANGGPNKVASHEGAEKDHTTPYPTMLIPPSQGSQLLNRVQNKADVETPLSQLKRERLKDRGGDVYISPRAKANLRAKDDFDLTSKVEEFLESEKKVFLILGDSGAGKSTFNRTLEINLWDKYNADGRIPLFVSLPTIEKLERDMIAERLRQANFTENQIRELKLHREFILICDGYDEIQGTQNLYITNQLNKPGGWQVQMLISCRTEYNGSDYVDCFQPAERNNGGDTDLLQEARIMPFNKDQIQEYIDQYVSLRKPTWRSEDYLQALKQIPNLQDLVKNPFLLKLALEVLPRLLNTNSKFSTARITRLNLYDEFVAQWIERGKRRLGEMDLSPRDKEALSQMTEFKEHGIMYLKELVTAIYENQDGKPIVKYSVHRDRKTWKEEFFNDRDGRNLLREAIPLTRNDYEYQFIHKSVLEYGLALAVYDPNDHNEDTEPRSAGSRRESTSSILSFEQLQTGNTATTAENVLLNSPLGKRNLVHEQSVLQFLAERVKQQPVFKDQLYSIIEQSKTDKSVRTASANAITILVRAGVQFHGADLRNIKIPRADLSFGVFDSAQLEGADLRKTNLRNVWMRHANLRGAQMTGVRFGELPLLREDNRVFCCTFSPDGKMFAVGLAYGNIGLYETSSWDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPJ1</accession>
    <name>A0A9P6MPJ1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_002446</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001602">
        <property type="protein sequence ID" value="KAG0009396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPJ1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040455968" evidence="1">
        <location>
            <begin position="24"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0009396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="79" mass="8863" checksum="6AD2A7F101E3EA1E" modified="2023-09-13" version="1" fragment="single">MAKYNRVLACLMAMLLLAKIVNASFAYCIGLRDASLIRTVAGFYLWNEDGSGGHSYDTITRGRSMTLRDNGWTIKPTWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQ73</accession>
    <name>A0A9P6MQ73_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GTP-binding nuclear protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">GSP1_1</name>
        <name evidence="6" type="ORF">BGZ80_002168</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the small GTPase superfamily. Ran family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001527">
        <property type="protein sequence ID" value="KAG0009671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQ73"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000054">
        <property type="term" value="P:ribosomal subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:003472">
        <property type="entry name" value="GTP-binding nuclear protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002041">
        <property type="entry name" value="Ran_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24071:SF0">
        <property type="entry name" value="GTP-BINDING NUCLEAR PROTEIN RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24071">
        <property type="entry name" value="RAN GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00627">
        <property type="entry name" value="GTPRANTC4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51418">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3 5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0009671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="128" mass="14762" checksum="9240A17026D97DB4" modified="2023-09-13" version="1">MFDLTSRITYKNVPNWHRDLVRVCENIPIVLCGNKVDIKERKVKPKAIDFHRKKSLQYYDISAKSNYNFEKPFLWLARKLAGHQDLEFVAAPALAPAEVSVDPTLMAQYKEELNSAAQMPLPEEDDDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQE4</accession>
    <name>A0A9P6MQE4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_001711</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001397">
        <property type="protein sequence ID" value="KAG0010170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQE4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0010170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="440" mass="50394" checksum="4F9CA995A2214041" modified="2023-09-13" version="1">MQKYASHIRSIYFDFYVYELAKRLPWEAMTQIQEIHMTEEIKGDDIQERVVHLIERNRGLCKVVFHSSKIATTRKVAKTLSSYSNLKILKLYLGKIDSKMTAQLLDIATRLQELMICAKEIVIPNSLDNWTQFPSMTALSLSDKSGLSLHQQLEIIRRCPRLRRLCWVTVDAPLPIPDLCQVISTNCRELSELDFLPITGKTTGLTVANISDEEIAHLVNSCNDLTVLKFYPSGSGSLAIQAIRPHFSKLTRLEVPGGHLFDSDIIQEIMTSCPALIELKADRLYARSILGAVKSDAPEPGSDGYDLHPQDWVCLNLQRLNVFICGLHNSDMWQRQILYQLSRLKKLEELSVGGWDDERSWGRDGLDLRLVRGLDILASLKQLRTFEFRELYQQQGEQEIRWVLREWPKLTSFYGRYNANRAVDQQLASILSAHRVNSGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MR65</accession>
    <name>A0A9P6MR65_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BGZ80_001821</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010001424">
        <property type="protein sequence ID" value="KAG0010063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05610">
        <property type="entry name" value="STKc_MASTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000604">
        <property type="entry name" value="AGC protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000550">
        <property type="entry name" value="Serine/threonine-protein kinase greatwall"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037638">
        <property type="entry name" value="MASTL_STKc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050236">
        <property type="entry name" value="Ser_Thr_kinase_AGC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356:SF1">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE GREATWALL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="1807"/>
            <end position="2143"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="12">
        <location>
            <begin position="2144"/>
            <end position="2174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="53"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="96"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="282"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="359"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="418"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="575"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="694"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1112"/>
            <end position="1200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1232"/>
            <end position="1258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1328"/>
            <end position="1355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1387"/>
            <end position="1414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1622"/>
            <end position="1674"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1692"/>
            <end position="1732"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1754"/>
            <end position="1779"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1985"/>
            <end position="2047"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="67"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="97"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="132"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="282"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="359"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="371"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="421"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="484"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="494"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="507"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="578"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="593"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="620"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1159"/>
            <end position="1168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1169"/>
            <end position="1192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1337"/>
            <end position="1348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1390"/>
            <end position="1402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1622"/>
            <end position="1632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1705"/>
            <end position="1732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1754"/>
            <end position="1763"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1989"/>
            <end position="2000"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="2017"/>
            <end position="2034"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0010063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="2174" mass="236848" checksum="76976B11B8D53E1F" modified="2023-09-13" version="1">MPNSATLARGMDSEPKTYLTRDTTGTAPLNVNPILESIVEVERTIDHAQTTTDTQIEGNSILAGSISDPSSAKSTPQINRRIPALAPVIESGREDTTSSVLFSPQEQSRDISTVARSLSSVRPQQSDKRDSLTSGVSPMPNTSSPRIGRSNTISGIIHSPAVTVNLDQFAPKVPLELSPSSTQPSTVITSEKSAWPSVVSNPEDIEQYRSELSISAYRSLLNTQLKSNNHLCGSQSVNSLSATTISTSGISTPATSITSLSPNVPHNATAPVFLASHLHTQATPSAGPQDQSKSLSRDSSWHHIKSSNSNASMLSSSNSYGYDGGFDQSAPSSRTSLHVKRSSIGSACGAKIRLSPMNIKQGQDQQHQQYSPSLSSDSGSPSPTSSSPLMSSASSTSSPHSTISWKARLRRSLSNHEKLQSPLSNVFNPDMAQSESGDGKSSSENLALDDQPGYTQLHEKDYNTDPESSTGSGDDEDYLDEHQQIVTPNLSPQASASRSRSSADSGKSNDCRGIKVSESSEPRYSTGSHRESAIDRFIPIAQPHSPYLESAGIALSAPTRSSSNSSHQYHQRLPIHIRSPSQGSQGRSQGRQRQREINRSIDSHRSSSQEDQDFSPPISPIAANIPSPYSATSSMQPTEIPIVRRTSSLASSPSSYHRHHSVYVLSGQMFKHSPQGSPKSHLARVLASDQDNNYYTTDSDSDSWGAKQLNRKKSTDRVFSDSDAEDDQKQKRAPIRGFHLPPRTFRSEYDSDNTTASANGFGAGRLDKLMSSPSLNAFGGTSIVTSSSLPAFFPDLSATAPQNLVSQIGFMDDTNELNAASALIHEIVQTKSRSDAEIRIILDGWYECKRDKDIACLSFQQGIPEPSGPIWANDGDTDFPTQMSVLRDIQGTSPAFQPHPDSDNWYESKIGPLDRVPAVKESTMKRSSRHNSVSHNSVSHNDANVEWEAAFLPNKGQTDAYPNASKDGDIRRVSKLSPIDVPPPNNNLTPEEEEINLRAVSRKRSILSRRIIASNSWPPTILASSHTTLLISIECISQQILHTPVSAIIDHPLKAVDIMKALQTLMDRQRRMAVGNAEAEDLLTKLVYVFAPVCRLAERLHEQRLNENYYRVEPPSGNLLQDQNSLFPDVDWSPLPSPAMPDQTPEGEVSKSPSLSNNHSKDGSHERSPTQNSAVDNPQDSSAEQRSPTVSTKSKKSLDHHLSEKYEGITPSQYVVAQHANAFPTGEIQFQSTGPLLKLPPPPNKRSSAPPLSRTTTASEIKTIVPSPSTSAPSSTSLVTVAVAIATDQKSSSLEPGLAPIHLKRSLTASTPGPSSISLRSFDAGLQRVESKDAASESDSSGMAGSSGKAKRVTERKKSAISLFKSLKSMFNQQQQQLQQHYTFNEKTVSPMSPSPLSQLSPNSPPLTSPTQPAKPGTFALRHRGSVASTTLMQPQTIDPASSQQMAQDSTVSTSDATVNLTVCRICDEEILISLLDRHSETCKLQHECSQKLESCNHALNKLSTCVWQRRDLIAGMNRPYVDYHSIKDSDKIQILSEKAYLVQESNPRHAIRKLEKYYQKVESILRESRHSAHDEELINISKRIARVIHEKLETMQTIQDQLTLLTSRDAGLDTTGAISRSQSASAISSQSENQPASTSFWGGRRKSKKAKESLPRSTKPPLPLTTSQTTGNVVGKHIGPSSWVDQELEAAPGNNPSHRKGIPIQSSLTRKTRSGSITGTPPAFPSTSVEKPSKNFSTIFATFLRVSRQRINSNNFSGQSKGASGDNESGRGGLFGTSGGAPSGVLSPPFNGTPPYKSRVPSIQDFEIIKPISRGAFGKVYLARKKTTKDLYAIKILKKADMVRKNMVSHVLAERRVLALTRTPFVVQLFYAFSSKDYLYLVMEYVIGGDLSSLLAVFGSFDEDMAKMYIAECVLALEYLHANGITHRDLKPDNMLVNAEGHIKLTDFGLSRISVPEQEDMTSLHDYKSSSISRRYIPRTKMTMPYASGKKGSTKKSSTVEAAHERNQGAAGLNNSTSPATSPTSSTYHSTLSGRTARRHRGSSKALLGTPDYLAPELLLGIGHGPAVDWWSLGICLFEFLTGYPPFMDEAPEAIFKNILNHDIQWPESGLSWEAHDLINKLLSRDPAHRPSPSVLKAHPFFQGVDWENIRNQEAPFIPAPNDNTDTSYFDGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MR72</accession>
    <name>A0A9P6MR72_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PAS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_001270</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001288">
        <property type="protein sequence ID" value="KAG0010671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053159">
        <property type="entry name" value="Hybrid_Histidine_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43642:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55781">
        <property type="entry name" value="GAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAS" evidence="2">
        <location>
            <begin position="1866"/>
            <end position="1937"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="255"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="705"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="705"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="727"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1941"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0010671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1941" mass="216880" checksum="596234F7AD04628C" modified="2023-09-13" version="1" fragment="single">MHTSPIQSQQDQIHDNPYKAPSQTNSWAFVPPKVPGYEFYGGSQSGNLGLMMGKRISDGMPVTGTLHLSRVLLQHEHRILKRLQIVNSGYDPDRAPPQQSHETDTEKASKASEDTAENSQSSGKSPGEEIPLPQPGLVENEKYLNRIVEDFLDLDQGEMSILIMRRLGPNLLSLHHHRYLGLEETDGYQVQDPSTERPIRSPFSDVYTFLVFCLKAACVLEALQRANLAHLALCPTAFHWSPFSSDLVAQNLERTARPNQRNPSSLYHDSDLPMSYEASQEPKQPMEATHQGHLFSSRPTHENDNSLKPDWNVNKTRLRLFDFTHSKILSHERARAPNNIAEWQIPGYLEYHLQYLAPEQTGRAETWMDHRTDIYGLGATLFSLLTMQFPNRGTDSVQILQGVLSRELPPLSLFRPDMPPIIDAILRKMTQKIESFPLGKYDVSYQFVLPSMVFGRNAEQQLISSVIAQAASAYQNSLNNDVSETCTEERDVAMKVAAVNDSDHYVFEDDIVSLQNQARTKIPLSSKTLLGTPKPFDGGKSVYRGSEATDPVVRAIFVSGSSGVGKSVLQQLLAQKSEPLASLVVAIRTAFEPNSGIGIICDLIPELNYFFRGTEIPESKDVSLTHSVARFHDLILKLIRVISTHFFMTWLIDDIQYADENSISLLATLVNVSKRLPIVLIMTHNDSPDCQMKVKQILGGSNVSDNNLNGGCEPSSNAGNDPLENDIPNSNPSSSGSIPMTKNAGSRASESPLVVRGGGGVRFIRLQSPTLDHIQEFLSALLHRSKTDVLPLATVLQHKSWLAIRQLVLELYKNQTIYFNRTTRAWDWESCPETLAELVRKLTGEEYSFLERRFRDLDCDTKKTLICAAICGSIFTIHDLQRLASTAYIWKKNEEEQPNHAPETISVDTNKGSNAMAGLQSAIREGLLVYTSLPDHLRWNHNVMRKVAIGLLQGTDEKERLHYEMVKILFKMPGQEFRTANHVLQCLDLVKKKIYPCVEEDLAKEKPYWVPDPEEDDDNKLDAKSLRVILSLAGEKSQKSGAQDLAIAYWNAAISLLPDNCWGRSNGSSDIDGSGDTPMMSEVEVEEGNLYRESLKLHLQCIEAERWKENFDRAMKLCDHTLANITDPIDRARVYQHQIEMSVWAYSQPPQATRIAIQCLQELGMSKDISFTPTQKEIRELYDQTHLMVLEHMSELESDNPRTCDDPRIAMMMEVLAVAKRGPLHKASILACRLSEGNHHVKFLFHLTVQQWGDHVANSVPALEETLQAADLACDRLFHTAGMIHVSVMHVLLGRINLRDCMASTLDLITKHIEFGPKSHGMEVMYGILQLIKCLRGQTHSGNPETIFDDNEFAESKMHGERNKALVMVHNNSTYTMLKIVASFVFCHYSYINEVTASWHDDPESMMNFEGSWISHSIFTVVGLSLVSLLRTEQDTEVREKLKSRLFVIRDRMAIRSEKFPTNHAAMFHLLEAEIADQALEEDTPNLKKVFLLYEKAIAYATKGNFPLHRCFAYELAAKCHLRHDLVTSAKCLMENACRIYQEWGARGKVVWFYKTYPDMFGSLPANETAPTARGLFYRPNGTDSRSTAGPLTTNVLSGTCSGSAFIGTGGSSGAGTSPWSGSPRTIYSPSGYGQDTVSAAATAIAESCMATNQQAGGTTSTNTLASPLSSIQTNWTASPQSPEVDNSDLDVLDFSSVIEAMQVIASEIDLDLLLVKSLGVLNQSVGAKRCCCLIISKDQEPILAASQGDSGKCESVIPPLEISKCNSLFHGVINYVINTSTPCLITNAKDDPRFCADEYLKQRPDLKTVMCAPILHKTAMVGLLYMEDFPERAFANKRILVMNLLVQQLGISITNALLYQSVLQSETKLNGLLENMPCGIALWDATAEKCQWINSSWSDMTGFTLDEIQDSEWKILTHQDEVAIYQNHWRERVQAGVPCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRL9</accession>
    <name>A0A9P6MRL9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Plasmid pRiA4b Orf3-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_001149</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001258">
        <property type="protein sequence ID" value="KAG0010830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRL9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.30">
        <property type="entry name" value="MM3350-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024047">
        <property type="entry name" value="MM3350-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012912">
        <property type="entry name" value="Plasmid_pRiA4b_Orf3-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41878">
        <property type="entry name" value="LEXA REPRESSOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41878:SF1">
        <property type="entry name" value="TNPR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07929">
        <property type="entry name" value="PRiA4_ORF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159941">
        <property type="entry name" value="MM3350-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Plasmid pRiA4b Orf3-like" evidence="2">
        <location>
            <begin position="7"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="283"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="283"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0010830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="351" mass="38182" checksum="7ED5522D20F3BD69" modified="2023-09-13" version="1">MEDQPEIYSVKITLRGSKPKVWRRVLVDSTSTLTELHEVIQYAMGWIGYHLHQFKIGGKFFQSNPLDEDFGFFGMEVHNGDEVRLNEVAEPGSKFIYEYDFGDGWEHEIFVEKVVPFKPSLDVPSCTGGACACPPEDCGGIYGYANLIKTMAGPDSEEKRELTEWLDEMSITRFDPKEFDKDLVNGQTLWTAGEPAEIRWQLKPNNSKTDLADITLVGGDYTAYQPIQLLGANVVLGIHKLPITKVPDVSCGSSCALQFFIKDGPGKGYYYTHNFTIAAPGATPATTTSSDEAATAAPGPTTQPSSPTTLAQSAAKGAQSQTANSAINDINKSTLSVMITAAISSAVAYLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRU7</accession>
    <name>A0A9P6MRU7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">P21-activated protein kinase-interacting protein 1-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">PAK1IP1</name>
        <name evidence="6" type="ORF">BGZ80_000864</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001190">
        <property type="protein sequence ID" value="KAG0011191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRU7"/>
    <dbReference type="OrthoDB" id="308449at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051959">
        <property type="entry name" value="PAK1-Kinase_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44675:SF1">
        <property type="entry name" value="P21-ACTIVATED PROTEIN KINASE-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44675">
        <property type="entry name" value="PAK1 INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="152"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="192"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="233"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="454"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="37"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="63"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="459"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0011191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="501" mass="54844" checksum="9067F5052363E61C" modified="2023-09-13" version="1">MDKNKKPLKSALKKTSSAPAAHASTNTNTSIKRKHASSVTTSTKPNAGNANKRAKPDNKNHNSKSVTAGSKINGNNKKGVTSVTGAKKGVAFSTPAVKKTVVHKPKKDVEVPEGATLEDFRIVAGTYENILYGVDAYWNEDMTLRLSPIFIFAAHIGCIKSLAIGGNYLASGSTDEKIQLYDLKRRKELGALLQHQGTITSLSFHNKTHMLSGSDDGKVCVWRSKDWECLKIMKGHQSSVHSIAIHPSGKIALSVSADHSVRLWNLLLGKQASMTRLQGEGLKVAWNPSGTGYSIMFDQELGIYDMATAKCIRTIKPARKTRMNTMAYYKDDYIIIGYEDKMVRVYSTATGDLVKTLVGHTNRIKAIDLISVPFTPEETSNKGFVGRPETKVVDILASVSSDGTILVWNLEDVVAPAASPEEINMKNHIGEHKTDMRVTCLSIQKGIWKNINVGNVGEAEGENDEDEDEEGEQEGEKAAEEEDEEEDEVDEDSAFDSEDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MS04</accession>
    <name>A0A9P6MS04_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">37S ribosomal protein S24, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">RSM24</name>
        <name evidence="2" type="ORF">BGZ80_001345</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001300">
        <property type="protein sequence ID" value="KAG0010612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MS04"/>
    <dbReference type="OrthoDB" id="283424at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019349">
        <property type="entry name" value="Ribosomal_mS35_mit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039848">
        <property type="entry name" value="Ribosomal_mS35_mt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13490">
        <property type="entry name" value="MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13490:SF0">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN MS35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10213">
        <property type="entry name" value="MRP-S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Small ribosomal subunit protein mS35 mitochondrial conserved" evidence="1">
        <location>
            <begin position="139"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0010612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="268" mass="30301" checksum="A7DA6AE59B1BF8CE" modified="2023-09-13" version="1">MSVVVAHSNILFAFRHPPFLSVRTGQDSNNALKQSVEYNSMLRSISRTPVGIAASVQRETVRTLMTSLPSTDRARSSALGAIRGSGSSKDMLDISNLEEFQFDDSTTVGYDALEAQREIRKYLRITKYELPKLKAFVKPFQPPTKTQILRFRTSTYIGEPNHPAAPKVVLTVDTKSLPLTNPELHKFLLLVGPRYDPTKGEIKMSCEKFQDRSQNFKWLSDTLDKLINEAKKDPESVSDVPLDLRHAAKSIKPKVRFPKEWNRPVKNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MS32</accession>
    <name>A0A9P6MS32_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001396</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001315">
        <property type="protein sequence ID" value="KAG0010537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MS32"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0010537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="72" mass="8230" checksum="002956A1D1DBE9B0" modified="2023-09-13" version="1" fragment="single">EHLWQDLKHQRHRADTNVSTAKSDSADRAHSVFTRIHTRESVHSSARKKDADDNSLSKAICDVICEFIVWDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MS66</accession>
    <name>A0A9P6MS66_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">DNA ligase</fullName>
            <ecNumber evidence="12">6.5.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BGZ80_000610</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11 12">
            <text>ATP + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m = (deoxyribonucleotide)n+m + AMP + diphosphate.</text>
            <dbReference type="EC" id="6.5.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 13">Belongs to the ATP-dependent DNA ligase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.1" evidence="12"/>
    <dbReference type="EMBL" id="JAAAID010001129">
        <property type="protein sequence ID" value="KAG0011536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MS66"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003910">
        <property type="term" value="F:DNA ligase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903461">
        <property type="term" value="P:Okazaki fragment processing involved in mitotic DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07900">
        <property type="entry name" value="Adenylation_DNA_ligase_I_Euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07969">
        <property type="entry name" value="OBF_DNA_ligase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000062">
        <property type="entry name" value="DNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.30:FF:000016">
        <property type="entry name" value="DNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3260.10">
        <property type="entry name" value="DNA ligase, ATP-dependent, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.30">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050191">
        <property type="entry name" value="ATP-dep_DNA_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000977">
        <property type="entry name" value="DNA_ligase_ATP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012309">
        <property type="entry name" value="DNA_ligase_ATP-dep_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012310">
        <property type="entry name" value="DNA_ligase_ATP-dep_cent"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016059">
        <property type="entry name" value="DNA_ligase_ATP-dep_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012308">
        <property type="entry name" value="DNA_ligase_ATP-dep_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036599">
        <property type="entry name" value="DNA_ligase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00574">
        <property type="entry name" value="dnl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45674:SF4">
        <property type="entry name" value="DNA LIGASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45674">
        <property type="entry name" value="DNA LIGASE 1/3 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04679">
        <property type="entry name" value="DNA_ligase_A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01068">
        <property type="entry name" value="DNA_ligase_A_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04675">
        <property type="entry name" value="DNA_ligase_A_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117018">
        <property type="entry name" value="ATP-dependent DNA ligase DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56091">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00697">
        <property type="entry name" value="DNA_LIGASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00333">
        <property type="entry name" value="DNA_LIGASE_A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50160">
        <property type="entry name" value="DNA_LIGASE_A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="6 12" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8 12" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="9 12" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4" id="KW-0235">DNA replication</keyword>
    <keyword evidence="2 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-dependent DNA ligase family profile" evidence="15">
        <location>
            <begin position="591"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="35"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="89"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00034003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0011536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="863" mass="96646" checksum="12A42C7228FC7010" modified="2023-09-13" version="1">MSLRQSRLSFGPKTPLVASSAKSEKDAGKDGGITENRNSGSQSNGKATSESNVEPIKDSAMEEDESEVVKVRKRVRRTIQSDDEEEQVTETVVSDVKVSSSTQDHRDEELTATTKKLKLDPASPKKPKAQPIDTKDTQTVAKEVEPDVTKDIGNETPSVDEAQEEDEDQVDLIEQKEAVEIKEAAAKWADMLSSSTDMESASWKKGEPVPYAALCQTFEQIEDTTKRLQILDYLVKFLISVIKQSPESLLTVIYLSINKLCPEYEGLELGIGESLLMKAIAESTGREMKKIKADYAEIGDLGIIAMVSGRFGFHPPYRDHQCNEPTLANTKSKPDFQNSRSNQPTMFKPKALTIPHVFKTLKDIASLSGNSSQKQKVDKIKLLLVSCRNKEAKYLMRSLEGKLRIGLAERTVVVALAQAIVLSRPDIKKLSKEKLQAELEEAASVVKSVYSELPCYDLIVPALLKTDIKGLKEACKLTPGIPLKPMLAHPTKALTDILDRFENIAFTCEYKYDGERAQIHKLDDGSMRIYSRNSENMSTKYPDVMERLGKFAKAGTNSFVLDCEAVAWDREQKCILPFQVLSTRKRKDVKEEDIKVQVCIFAFDLLYLNGESLLREPLARRRELLTEHFNEVDGEFAFAKSMNSTQIEDIQTFLDQSVADNCEGLMVKTLNGDEASYEPSKRSRNWLKVKKDYLSGVGDSIDLAVIGAYSGRGKRTGVYGGYLLACYDPDREEYQSICKIGTGFSEQDLEDHYKELKEHVIPDPKSYYVLGEGNKPDVWFAPVRVWEIKCADLSVSPVYKAAVGIVDSTKGISLRFPRFIRVRDDKQPENATSSEQIAEMYNDQKLNTVKNDTSLGVDVDFDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MT45</accession>
    <name>A0A9P6MT45_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_011576</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000949">
        <property type="protein sequence ID" value="KAG0012686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MT45"/>
    <dbReference type="OrthoDB" id="2441994at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.940.10">
        <property type="entry name" value="Functional domain of the splicing factor Prp18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF288">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="451"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="752"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="793"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="15"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="71"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="90"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0012686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="837" mass="93482" checksum="3B1A0E18DC3B2462" modified="2023-09-13" version="1">MDPSIANPPRKDNEGNEVDEADDQFSVDRPVWASETSTASQDLAPPPTYDPSAFSAPLNSLPTFKPRKSNRVSVLSYSTDATTPPMTSNSPPPATGPAGTTPPPGGIKLPPPPMKGAGSGPAPIPYTKGDFRTAEIVNHWNDPPTQIFEKGAKGGESTTYDFGHMNTTLTAIIKECSANVPAPQKRMFEDTTKRLQSLQDQMDNGTVNERVVTPLGDMIQGQSDLHPYGNYNGAESVNMDSLPSLSHSTLSSASDVMEFDSMPVEAHQAHIAAYGQHLENDLRRQNVVVPQHQQQQQQQQQQQQPLLLQQYQQQQLHHQQQQQYQFSPQNFLDAEKQLGYQFLPQLQHQNLQPAWPRQANDQHAAAVPLTENCVETNMPSLTEDHSTNSSEMLQSASSGQGPVFPHIVDHGAGAAVNGFEDDLEYFTTSVLNMIPVGISDNATPMIDYTEFKDRRLIAKGGNGEIRQAFWESRNCRVILKSLITTKRSSTNLSTLFDKEVEVLRVCGNHDNIVQFYGISDRTQEDKIERFMVMQYYECGDLVKLLEGPRLTPEELTFDDRLSLALDIVMGLDHLLRCGFHHGDLHPKNILIESYPKTAPSSHNRNGYRARLTDFGLRRIRDNTNEVSSQPLGGVWQFMAPERMYKDRQSRPRYNVRCDIFALGVIYWYLISGRYPFRDRTIYTPKIREERVEGTEDWYYALYTQAWSEDPNDRQESLDEIIQVLRSRIPSSSAHIGQSQAQHAYAASPPTRQELYMPADGNRVHHGYSPGIDPSLSGGSSGVAPAMSAFQYAFNMPTPTPPSAAVPKSSARSSNPNHPRNKKQDVPNGMPGRTIRRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MT78</accession>
    <name>A0A9P6MT78_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_000294</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001057">
        <property type="protein sequence ID" value="KAG0011976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MT78"/>
    <dbReference type="OrthoDB" id="1695362at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18870">
        <property type="entry name" value="NUDIX_AcylCoAdiphos_Nudt19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039121">
        <property type="entry name" value="NUDT19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12318:SF0">
        <property type="entry name" value="ACYL-COENZYME A DIPHOSPHATASE NUDT19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12318">
        <property type="entry name" value="TESTOSTERONE-REGULATED PROTEIN RP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="7">
        <location>
            <begin position="8"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0011976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="304" mass="34495" checksum="E77311EC050B77DD" modified="2023-09-13" version="1">MSSEQAEKFRDSSTLIIAAPMPKSMVQPGKANYKVLLLKRSRIGTSASAHVFPGGNVDKADHDPRWATLVNYKPQGPNAPPLHNAICAIREAFEESGVLVSEPQIGLSDSEIGIWRERVHNDGQEFYNLCVSHNVKPAVERLEHFSSWTTPPVEPKRFRTQFYLTVLPWSRDSFSESRVFADGKETTRLDWFTPEEALEAYRSKEIQTFLPPQFVTLSDLLPVKQHENLLEYFKGREVINTMPEFVLESQDENGLHLSGILPGDMDHSFHAKNGFTHRIYVTKSKKGMVVRKYVNGANEIKARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTZ2</accession>
    <name>A0A9P6MTZ2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_011738</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000982">
        <property type="protein sequence ID" value="KAG0012448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10258692at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032991">
        <property type="term" value="C:protein-containing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1880">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051571">
        <property type="entry name" value="N-CoR_corepressor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13992">
        <property type="entry name" value="NUCLEAR RECEPTOR CO-REPRESSOR RELATED NCOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13992:SF39">
        <property type="entry name" value="SMRTER, ISOFORM G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SANT" evidence="3">
        <location>
            <begin position="1064"/>
            <end position="1115"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="3">
        <location>
            <begin position="1334"/>
            <end position="1385"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="3">
        <location>
            <begin position="1558"/>
            <end position="1609"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="4">
        <location>
            <begin position="1563"/>
            <end position="1609"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="2">
        <location>
            <begin position="1563"/>
            <end position="1605"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="263"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="502"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="552"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="618"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="709"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1119"/>
            <end position="1155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1195"/>
            <end position="1251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1263"/>
            <end position="1317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1391"/>
            <end position="1553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1610"/>
            <end position="1706"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1749"/>
            <end position="1768"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1788"/>
            <end position="1843"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="50"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="273"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="298"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="336"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="346"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="466"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="520"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="552"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="575"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="624"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1123"/>
            <end position="1136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1196"/>
            <end position="1226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1238"/>
            <end position="1251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1271"/>
            <end position="1288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1303"/>
            <end position="1313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1428"/>
            <end position="1452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1503"/>
            <end position="1517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1540"/>
            <end position="1553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1623"/>
            <end position="1646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1802"/>
            <end position="1820"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0012448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1890" mass="212644" checksum="BDB49C71251950DE" modified="2023-09-13" version="1">MGFQESPRLKFPERFQPRDRFRPPESLKNSSVMIDHSGQQSAASRYFGASSAPSNSSISHPRDFSPPTNYKNSVNEPNGGRSADSYSGVSPNMGPSIGPGLGSARYGDREDWRGRVNQFPREFERDRDYRNRDIRQDIRDIRDSRPPRDPRDTRDPRDVLSRERELRDRDMLYQRDPDYRDRDPRDRDLRELGITTRELRDRDNRDRDPRERGSWSSDIKGRETFSGREVPDLDVRELVERERERERDRNRERPIWLRDLEKDFDGNIPTRPALDHINRDRDRERERPSNSRPMTRAQEPDRDTLMYASDKPRQAFGKTEESPHGADRGTLKPASLPNSSFLNTQREPKSHDGDDIRDRDRTRDRDRFHSKEDERESFSRESVADRGQQRDRERDFYNRPDGAGLRSDVDSRQRNTVINKRPRILSAPTLEDISYREPSGPQSRELHDRSSYPNSPATAVGPFSGRIEKNEKQDDRRQDQRPEPLLNPLAMNADFYANRDQQTEARSVQDPGPVGDISTDDSRRLITHPDRSDDDLANEPIPGLFLVTGSDFRSEKVTERNQPEKDASESLRAVDSSTIPANRVNTSDINGGTDTDVTNDVPKRATILQEMLAIVTNPLEQEESAPSKNLDDSTSANDTVVSKDSNTDKVAKSPSMTSLPSPGLSPVQEVAAIDTPGEAAEFESHDDILEKIDTIDVKIQHVEDRLMKYRQQKEQPKGETQLTSPLDPGEDEDAAIDIEQPDTERGAEDIVMETVDKFTLASAVSAQDDLKSEDSLMNVRDLPSPVDLVPDRDMEDPRLEVTECEDVDMTASDAEVGKDRRRQIVQQFSRQELQNAIDEDDPFYKRKAQQKRRPQLYDQIYAENNTRAKKYGRVHSAIGSSREHGHHQNEQTKPQIYESVEDYPFYQENIESHMRLRNAMLHNMATKATALDEKELELKREYKQHWESWIKKVEKLDKIKEKMSNAPLPANVREEDLVQSDNVLFTTRNRRGTYNSDAVRSEAELMEIIQSLENADMRNPDLRASRTAATVPPMILDPYIREKVHYFDRNHLVTDPAKYYRLGPVTDIWTEEEREIFIKRYLNYPKQFGKIAAGIENKTASQCVLFYYREKKKIGFKEMVSNRGRKRKPAANKRKEKVVQQPSPSGQPGKKHKGSALIEDIGQANRKMAKNKEVRELHDLQNNWADFDTKRRVRGSATSLQSGTPNFDESNSNVASPALSAVSTPASAAGERRKQRSKATNTRSSTAAASNIKALTEDAVIEGKKPKTEKAPPASAVVAPASAKTASKGGEAVTAVESPKVNPASTSKQSQISAPEPVEASVTAVGATPAVSTGGVARWTPAERETFIVAFKKYGRDFEAVANAVGTKTVEQCKNYRFNYKRRYGVSALDDTSNQEAGGLGDGGEDKEISSTGVEKNKAKKGKGPNSVVISTPNTPQSTTVNVNRDISTTPSGRRKAVKPPVQEAVKDDLPKEPSIQANSAEEPEAVADKKRKKRAVSKSDAGSTPTEPMPTPSGTSFRARYSRDPSEASSPSIPAVSQVEDQFPSQANVDGSARRTNFSSYWSRQERIDFTRLLSLHGKNWDKISNALKTKTLTQVRNYYEKLAVDGIIGIDRPGSSPPPYKENEETSVEDKGVQQTDEDGHTDQDIGEQDDEQGPAAYTPSEGTGPKTGYFMPQYHEDDKVASNQEESLRAATPPRRITNIGNLLNNDDEDVSVAVEDWFGNNEEGSNTQSPVHPYEADGLPVRMQDSTQSQRYANDRSRMGDEDVETEDEYEPVHSAHGIYGSSATGVQTTSHRHVSDTGVSSVRYSSNTPTPSYYNQAHHHPHSSQLPPGHTMSGALGSPQVSVNARPCRIRVPTSACPRVMDMRSLRRMFSMDMLSPMVRTTRVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTZ7</accession>
    <name>A0A9P6MTZ7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BD-FAE-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_011035</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000839">
        <property type="protein sequence ID" value="KAG0013493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTZ7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049492">
        <property type="entry name" value="BD-FAE-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF33">
        <property type="entry name" value="KYNURENINE FORMAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20434">
        <property type="entry name" value="BD-FAE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BD-FAE-like" evidence="2">
        <location>
            <begin position="10"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0013493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="253" mass="28356" checksum="4435ECB39929199F" modified="2023-09-13" version="1">MGSKKIVGPLLTEMISYDWIVVSVDYRLCTKAGYPTQLIDCKRALRWVKEEIRVFGGDPNNIVAAGDSAGGQMACLLSSTANLPEYQPGFESVDTTVQGVLGLSPVCNLVDLENYSNHPCRERFIKEVALREGSPESAENLKFLTEHSPRFRIKGASVPHMMVHGDIDTLTPVQHTRDFVDHFRSTCTAPISYLEVPGGHHCFHLISSPRTWYMVIAVSQWLNYYFDSIHNIDSKVGTKGQQVHEIVEWGWST</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MU79</accession>
    <name>A0A9P6MU79_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">Glucose-6-phosphate 1-dehydrogenase</fullName>
            <ecNumber evidence="3 9">1.1.1.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ZWF1_3</name>
        <name evidence="12" type="ORF">BGZ80_010977</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>D-glucose 6-phosphate + NADP(+) = 6-phospho-D-glucono-1,5-lactone + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15841"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57955"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:61548"/>
            <dbReference type="EC" id="1.1.1.49"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 9">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the glucose-6-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.49" evidence="3 9"/>
    <dbReference type="EMBL" id="JAAAID010000827">
        <property type="protein sequence ID" value="KAG0013582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MU79"/>
    <dbReference type="OrthoDB" id="60984at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004345">
        <property type="term" value="F:glucose-6-phosphate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009051">
        <property type="term" value="P:pentose-phosphate shunt, oxidative branch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.360.10:FF:000015">
        <property type="entry name" value="Glucose-6-phosphate 1-dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00966">
        <property type="entry name" value="G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001282">
        <property type="entry name" value="G6P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019796">
        <property type="entry name" value="G6P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022675">
        <property type="entry name" value="G6P_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022674">
        <property type="entry name" value="G6P_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00871">
        <property type="entry name" value="zwf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23429:SF0">
        <property type="entry name" value="GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23429">
        <property type="entry name" value="GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02781">
        <property type="entry name" value="G6PD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00479">
        <property type="entry name" value="G6PD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000110">
        <property type="entry name" value="G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00079">
        <property type="entry name" value="G6PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00069">
        <property type="entry name" value="G6P_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5 9" id="KW-0313">Glucose metabolism</keyword>
    <keyword evidence="6 9" id="KW-0521">NADP</keyword>
    <keyword evidence="7 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-6-phosphate dehydrogenase NAD-binding" evidence="10">
        <location>
            <begin position="20"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-6-phosphate dehydrogenase C-terminal" evidence="11">
        <location>
            <begin position="199"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0013582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="512" mass="57549" checksum="9FC564084F0A4E4F" modified="2023-09-13" version="1">MSSPDSQATKTTSTHLYTIVVLGASGDLAKKKTFPALFGLYKNNYLSHQTRIIGYARTKMDQATFEGHVSKYIKLKSDEDNAALKDFLKLCSYVSGQYDKDADFQNLEVRISEVEKTSGAEARLFYMALPPSVFIPVSESLKKNNYKEGKIIRLIVEKPFGMDLESSRKLARELGALFSEEEIYRIDHYLGKEMVKNLMILRFANAIFGSVWNRHSIDNVQITFKEKIGTEGRGGYFDEFGIIRDVMQNHLLQILTLVAMEPPVSLDAEDVRDEKVKVLRFISPIEKDDVLLGQYGKSEDGKELGYLDDKTVPKGSKTPTYAAATLFINNERWSGVPFVLKCGKALNQQKTEIRIQFKDVVGNLFKSLSRNEIVIRVQPGEAVYVKMMNKEPGLGMKTIISDLDLSYSSRFNDSVIPEAYESLILDALNGDHSNFVRDDELDAAWKIFTPILKTIDEGHIDPVTYPYGSRGPAGVTEFVAKYGYHRGSQEYVWPQHSEAGTGAAGKDQRASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUR7</accession>
    <name>A0A9P6MUR7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9 13">Ribulose-phosphate 3-epimerase</fullName>
            <ecNumber evidence="8 13">5.1.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">RPE1</name>
        <name evidence="17" type="ORF">BGZ80_011054</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>D-ribulose 5-phosphate = D-xylulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:13677"/>
            <dbReference type="ChEBI" id="CHEBI:57737"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="EC" id="5.1.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="15">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Carbohydrate degradation; pentose phosphate pathway; D-xylulose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7 13">Belongs to the ribulose-phosphate 3-epimerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.1" evidence="8 13"/>
    <dbReference type="EMBL" id="JAAAID010000841">
        <property type="protein sequence ID" value="KAG0013474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUR7"/>
    <dbReference type="OrthoDB" id="1927044at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004750">
        <property type="term" value="F:D-ribulose-phosphate 3-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00429">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000171">
        <property type="entry name" value="Ribulose-phosphate 3-epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02227">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026019">
        <property type="entry name" value="Ribul_P_3_epim"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000056">
        <property type="entry name" value="Ribul_P_3_epim-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004076">
        <property type="entry name" value="PRK05581.1-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01163">
        <property type="entry name" value="rpe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11749">
        <property type="entry name" value="RIBULOSE-5-PHOSPHATE-3-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00834">
        <property type="entry name" value="Ribul_P_3_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001461">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01085">
        <property type="entry name" value="RIBUL_P_3_EPIMER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="12 15" id="KW-0170">Cobalt</keyword>
    <keyword evidence="11 13" id="KW-0413">Isomerase</keyword>
    <keyword evidence="15" id="KW-0464">Manganese</keyword>
    <keyword evidence="10 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton acceptor" evidence="14">
        <location>
            <position position="36"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="14">
        <location>
            <position position="172"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <begin position="143"/>
            <end position="146"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <begin position="194"/>
            <end position="195"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00005016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00009541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00013188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00013920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR001461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0013474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="224" mass="24031" checksum="5F9E38E64157F1E1" modified="2023-09-13" version="1">MPIAKISPSLLSGDFGILAAECKRMVSHGADWLHMDVMDGHFVPNITIGAPVISCLTKHLDAFLDCHMMVSHPEKWVDDFAKAGASLYCFHIEATQNASALIDQIHAAGMKAGVAVKPKTPISTVMDLGDKMDMCLVMTVEPGFGGQRFMAECIPKVKELRAKFPNLDIEVDGGIAMENIDAAAEAGANVIVAGTSIFKADDITGTIETFRNKVNSEQALLAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUZ7</accession>
    <name>A0A9P6MUZ7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Crinkler effector protein N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_011207</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Host cell</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000874">
        <property type="protein sequence ID" value="KAG0013240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUZ7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043657">
        <property type="term" value="C:host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045379">
        <property type="entry name" value="Crinkler_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20147">
        <property type="entry name" value="Crinkler"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Crinkler effector protein N-terminal" evidence="4">
        <location>
            <begin position="5"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF20147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0013240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="78" mass="8656" checksum="AE7EB54671AFF5B7" modified="2023-09-13" version="1">MTNRTLFCVVDGESSWRAFPEVVSPLDYIGSVKVLIKAAKEPQFDNMSADELTLWGVELHISEGNRDNDSTNLALLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVC1</accession>
    <name>A0A9P6MVC1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BGZ80_010932</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. GCN2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JAAAID010000819">
        <property type="protein sequence ID" value="KAG0013647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004694">
        <property type="term" value="F:eukaryotic translation initiation factor 2alpha kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004713">
        <property type="term" value="F:protein tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000077">
        <property type="term" value="P:DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110031">
        <property type="term" value="P:negative regulation of G2/MI transition of meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009893">
        <property type="term" value="P:positive regulation of metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd14012">
        <property type="entry name" value="PK_eIF2AK_GCN2_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd23823">
        <property type="entry name" value="RWD_GCN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14046">
        <property type="entry name" value="STKc_EIF2AK4_GCN2_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000050">
        <property type="entry name" value="eIF-2-alpha kinase GCN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000379">
        <property type="entry name" value="eIF-2-alpha kinase GCN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="entry name" value="Anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050339">
        <property type="entry name" value="CC_SR_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016255">
        <property type="entry name" value="Gcn2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041715">
        <property type="entry name" value="HisRS-like_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024435">
        <property type="entry name" value="HisRS-related_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006575">
        <property type="entry name" value="RWD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042:SF136">
        <property type="entry name" value="EIF-2-ALPHA KINASE GCN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12745">
        <property type="entry name" value="HGTP_anticodon2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05773">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13393">
        <property type="entry name" value="tRNA-synt_His"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000660">
        <property type="entry name" value="Ser/Thr_PK_GCN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00591">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50908">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 11 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RWD" evidence="15">
        <location>
            <begin position="15"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="14">
        <location>
            <begin position="258"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="14">
        <location>
            <begin position="610"/>
            <end position="1046"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="198"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="552"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="687"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="760"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1604"/>
            <end position="1645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="198"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="209"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="692"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="767"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="882"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="616"/>
            <end position="624"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="639"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="640"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="16">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000660-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000660-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0013647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1745" mass="197921" checksum="2BE92C7E6EE864FD" modified="2023-09-13" version="1" fragment="single">MTGMNQDELYELQQNELEALRAIYMEDYQPVTVPSAWKTVSTTPEFRLHLLPQEDELKRYVSVDLRVKFTKTYPKTIPDLKIENPRGLSTAQVEELSKKVPIQAKTLIGQEMMYELASFVQEYITQNYSSMFIKHPSFHEQMLQRVEQTNKDEKERAIEAMTRQQELELEAKLNADRTLDQKIREDLMRKEEKIKEEKKRQKELKNKQQEQFSGEYLESGRSGSGGGSGYGLDAVCINFETPIMISPDDSQAPAFRSVIRGSCLSRGVLSSTYSALPSNYSARPHSSADVPFLLLKTFDITTHHYTTPLGKKKLQDVEKELSRLKILRHHHLVSILESRLERTANGWNLHVLTDGSSANMTTFESFINIAGSVKLNMTRRYLRELLQAVAYLHSNNIIHKDIRLRNIVLDSNGNIKLNNASYHRRLLDMHKTFSFNTDAGQEVPRAWPSPDPQETSIVYTRKHDIWCLGQVLVEMLWGNDVTRSFKSPSQFLESVDSSIPKLTKDILSRMFEMDAKKRPSATDLLNDPFLGDEANDDNNLAQFHMYRDTDADSKLGIRGSHPPSTINIPLPRVGRESSRLDDMYVDDSINQLNTSPPTGNNLYSRYKSDFEEIEFLGRGGFGEVVKARNKLDGRFYAIKKIKLDPKDNVTNRKILREVTTLSRLHHQFVVRYFTTWFEDAGGASWSENKLDSEDESEEDDDDDDESDEEVSFSNSNRMVKDMKYDFLSEGDSNRNRSYPNIHFGHRSRDVSCRGESSFGMNGLALDSSEESTEEEGSNSESGSESDYESESDSGSDSGIRFESEGADGAAVDVRPRTTNIKKKKRPAPRPSRTLYIQMEYCERQTLKDLIDIGVDPDDGWRLFRQILEGLVHIHSQGMIHRDLKPVNIFLDANGDVKIGDFGLATSNSQVLVDLKSQSQAVTETILMSRSASYDRAHDDGLSLTTGVGTVFYVSPEVLNGAANGVRYNTKADMYSLGIIFFEMCYPLSTGMERAMTLRNLQQPEIIFPKEFPMDKMNAQAQVIRALLNHNLKERPSSLELLQSDLLPPKLEDEYIQECVRTIANPNTPYYHRLMTALFAQNADKHKDYTYDFNAENKAYDNFFPLFYGKVRDQMVNIFRCHAAVELGTPLLTPKSDLHDSDKKSVALMDSTGGLVQLPYDLTMPFARFICRNGITQLKRFYFGRVYRENTVGGQPQIVHEVDFDIVHNTHNPMVTDAELIKVVDEILEDFPPFKASNGVSFLVNHTMVVEAIFDNCRIPSEIRSGVYTILGQLGRQYQHMSQVRNHLLSVYHLPRSVLDELELFDKKGDLETVAKALEDLITAEPMKTKLKDALGELRLLMTYCKNLGVRHKIVFSPLLMYNNQYYKGGMMFQAVDNAKRKNILAAGGRYDSLIQHFRHPVIGGPHRKVFAVGVNLAMQKFVTAISQYQSEHFRYFMTSNKSNRGHGGPGGNSSIHDEEKSFGFWAPKKCDVFVASFGKVLLQERLELVKELWAHGIRADYMLEDGTDLTPETLVTTCKHQSINWIVILKNKNQQDSQQRSSRDLMGLVKVKNVLRKTEDEVPRSELCILLKAEIAEQTRLDVQAAASGGLGGIGSRTRKFADANTGHHHHHSLDTTAGSVSARHGHDHHHNSSGESPQVHPDFNVNVVSSSRNRLKHKQKTMLIDKAVNNLMGVTKNLAAGTVPVLAVDLSKDSVRKLAQCNVVEDDSFRKNVLDQLSPSQREYCLTIREAMLKARQEEGGQKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVE6</accession>
    <name>A0A9P6MVE6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_010033</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000657">
        <property type="protein sequence ID" value="KAG0015130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVE6"/>
    <dbReference type="OrthoDB" id="655030at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050562">
        <property type="entry name" value="FAD_mOase_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356:SF2">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356">
        <property type="entry name" value="FAD-DEPENDENT MONOOXYGENASE ASQG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="7">
        <location>
            <begin position="8"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="7">
        <location>
            <begin position="293"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="440"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="447"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0015130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="461" mass="51778" checksum="2B0E3A4B00ED9936" modified="2023-09-13" version="1">MSRPEPPNVLIVGAGIAGLFLAILLERQKVPYMIYERTKESKPIGSAIGLDVKIMPVMEQLGLLEELKSISLPGAGVEMFDPQLKFMTAILFKGYEEVTGYVPLMFPRPELHRLLRSHVPEEKIVYSKKVLSLEQNEHGAMLRMSDGTTVHGDIVVGADGTYSGVRQGLYKHLEKKGLLPASDKEELTLGHLCMVGTTNPVDPEKYPCVNNEKALFQRVIGKGDPYTWHTVNMRGNKICWGIIRQMDSTVASRDKMFRNSDWGSEGDEGVMNGAFDKPTPIGGTVRDLFEATPKEEISKVFLEEKLFETWYYGRTVLIGDACHKFLPSAGQGAVNAMQDAVVLANHIYEMGEATPENITAAFKEYRDERYGPAKRLMAKSKLLAILQYGMTWKDRLIRYIMFNVIPDGIKMKQFYKDTMHRPQVSYLEYVEARGTGEVLPQKPSKRYAQEKAAAKGEEVPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVN7</accession>
    <name>A0A9P6MVN7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Terpene synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_010444</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000727">
        <property type="protein sequence ID" value="KAG0014435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVN7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0014435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="272" mass="31319" checksum="DE7B7B3E39A5C252" modified="2023-09-13" version="1">MIPINPLIEALSRTKQAITTAKVAIAVEELKQYWSELGLHHFEQVMDFTNCLLLHCEQLPQPEKSYIVAAATLNHSLAIDKYLLEDDDSVVDSIHAKYLGFLSRYLNEEEIEYYKHCFKTWVDSCQEVAVLKQSLPKVSNPVVRYSMWADWRSVNIGKTLYVRLIMMINFPNEDLHSAIAQSSIMYISMQTALLNDIASVIKDKGSNEVNYYLEVAPDTIEKQEDILEHSNKYLEMVNLSDNLKHVLTSTLHGSYLLYSLSNRYFGKTEPDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MW59</accession>
    <name>A0A9P6MW59_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">W2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_009496</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eIF-2-beta/eIF-5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000575">
        <property type="protein sequence ID" value="KAG0016007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MW59"/>
    <dbReference type="OrthoDB" id="10250831at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071074">
        <property type="term" value="F:eukaryotic initiation factor eIF2 binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005092">
        <property type="term" value="F:GDP-dissociation inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11561">
        <property type="entry name" value="W2_eIF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.350:FF:000001">
        <property type="entry name" value="Eukaryotic translation initiation factor 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.30.170:FF:000002">
        <property type="entry name" value="Eukaryotic translation initiation factor 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045196">
        <property type="entry name" value="IF2/IF5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002735">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016189">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016190">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003307">
        <property type="entry name" value="W2_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23001">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23001:SF7">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01873">
        <property type="entry name" value="eIF-5_eIF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02020">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00653">
        <property type="entry name" value="eIF2B_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00515">
        <property type="entry name" value="eIF5C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100966">
        <property type="entry name" value="Translation initiation factor 2 beta, aIF2beta, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75689">
        <property type="entry name" value="Zinc-binding domain of translation initiation factor 2 beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51363">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="W2" evidence="7">
        <location>
            <begin position="240"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="150"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="155"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="176"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0016007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="402" mass="44882" checksum="CD1E9B954F67510F" modified="2023-09-13" version="1">MANLNIGGQSDDAFYRYKMPKLVAKIEGKGNGIKTVIPNMSDIARALSRPSTYPTKYFGCELGAQVKCDEKTDRYIVNGAHDAPKLQQLLNGFIQKFVLCPSCGNPETDIIVDKTSTIQMYCNACGRRNKGENVHKLATYIVKNPPVNSAYGKKSKADKADKADKKSKKNGSSTPPEEEEEDRDDDFTKKIKEEAAAIPDADHYQSALGDGWSVDTSAEGAAARMKELEGNIKTQLTLDDDEDDEDGENPYELFGVFLEENPKATDAEILEKAGELDITTKSRAVTVLIQCIFTDDMAREIKTRAPLLRKFVVNEKGQKAVLGGMERVLITSKTLMLKAPLILKAFYDNDILEEDIILKWGEKPTKKYVTREEAKDVRTRVEPFLRWLAEAEEDSEEDSDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWB1</accession>
    <name>A0A9P6MWB1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_009572</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000586">
        <property type="protein sequence ID" value="KAG0015884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWB1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050562">
        <property type="entry name" value="FAD_mOase_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356:SF2">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356">
        <property type="entry name" value="FAD-DEPENDENT MONOOXYGENASE ASQG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="11"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0015884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="337" mass="37084" checksum="1339F5E857EC3FB9" modified="2023-09-13" version="1">MPGPVDTPIPTVLIVGAGLGGLMLGAILESTDISYHILERATELRPLGSAIALSGNILPAFEQLGIYEELRNASLPHISTDMVPAHKISMGKKVLRTKENDNKVAVYCSDNTIYEYSVLVGADGVYSAVRQNMYKQLEEDGNLPSRDKDAFSIGFITMVGISHPPDPAKYPELNDDNRTHFRLVIGENNDSVKSVDSMLKQFQDFPCGFGGTMKDIFDVTPRELICKVFLEEKLLPGAGQGAVMAMKDAVVLANCIYNMRDESDKSINAAFNSYHRQRHREADEIIKGSNIMTKIMFGHASIEQTPNQLAPLVENRGLGYIIPQDGRKDAEKKSHSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWP1</accession>
    <name>A0A9P6MWP1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_009779</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the acetyltransferase family. RimJ subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000616">
        <property type="protein sequence ID" value="KAG0015560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWP1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051531">
        <property type="entry name" value="N-acetyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43792:SF8">
        <property type="entry name" value="[RIBOSOMAL PROTEIN US5]-ALANINE N-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43792">
        <property type="entry name" value="GNAT FAMILY, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G00765)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="4">
        <location>
            <begin position="42"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0015560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="167" mass="18579" checksum="8AC982E921080532" modified="2023-09-13" version="1" fragment="single">ANAVRFTERHLQRRNEAGVVTSWAIRTSIAGPIIGLFAMDSFDHGDVGHCYRDNIQQTHNHVEDQSPRCADTIQAGTLNCGGLGYWISPEYAGKGIMSQVVSYGVNHLARKEFGYDRIHGEAWMENKGSQRVMENTGMRRTVGVPCFVPKFSAVRDIAHYIIDVATP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MX08</accession>
    <name>A0A9P6MX08_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_008958</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000505">
        <property type="protein sequence ID" value="KAG0016757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MX08"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010640">
        <property type="entry name" value="Low_temperature_requirement_A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42101">
        <property type="entry name" value="CHROMOSOME 16, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42101:SF1">
        <property type="entry name" value="LOW TEMPERATURE REQUIREMENT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06772">
        <property type="entry name" value="LtrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="289"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="347"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="380"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="407"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="437"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="462"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="560"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="590"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="621"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="228"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="693"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="834"/>
            <end position="891"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="707"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="721"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="739"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="840"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="876"/>
            <end position="890"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0016757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="908" mass="99841" checksum="F194C46F37CC2509" modified="2023-09-13" version="1">MSNNIQSFRRRTLERMYTNKSSKGTKDTPGELSSTAVTESFSANATGSSTGVARPIMPRSRPSLAQFRMKDQPSKMIIPPPYGRQVVQEAAVALAAGIPDGIPRSNTICGPDPRVSSDSESDDDPEVRLHIEIHLQENAETEPICPLSDKNLTKLTEELELTLQERTDIDAIQTKEELAAYFEKIPRDYDIDIIVSDKAPESPGVTFAQDDLIHSGDSIAVVRRESFKEKRSRRRKQKYRRPTTDLSTMPEEEPRASWLELFYDLLFVANLNNFTHSHPITGGAALGNYIAWFVIMWWAWAGQTFWAARYDMDDLFTKVWKLVESCALISFGAFSSDHLNHTSTGFIISYIVLKAVLAVEYGNVLYWARKNRSRKSLTPLLLQIGSNMLAMLVWGLSIIVHSQAGRYAMWFVTIAIEVGVLVSFGGRTSVTFAGSHLPERFALFTIIVLGEVFHGTTTLSQLWAYLHLPLHICLVLVGTGALDLIRLYKEEHNILDQESLSVKQLSSLESQFASLSSLGQSTRYVATGFEVPFERRSASTVVGSETDQSSDTDYDLTKRYFLVSCSLVFLFNSLIKWINLRSYDRFQKIVYFSRLLNAVFIFCLLAVPLHKMTSFVLLGSMALFCILQVAVDLAVIYFGAYGFVEDLEAWARSARSSIDLGSFLPSPLGGRSRRGSIASSKTGSVVSLNATLKGRSSTKAQRHTDNSTASSASSKGSFVSQTGESYASQQKQTHQSHLLPSSHGQTSSLSLQQQQELHNMHVNSNSLGSSGAYGNLVRALADIKKREQLDKQSGDALLPSRQITLSATERGYSTNTLTSSQAAVSLNRTGMGGTIHAGSNFDQRQPGTSGESNAHLTGYTRHGTSESLGASPPTPTSTDNGQDPTWSSAVPVSGAVGLANLFNQSPTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MX27</accession>
    <name>A0A9P6MX27_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Carbohydrate kinase PfkB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_009623</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000593">
        <property type="protein sequence ID" value="KAG0015807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MX27"/>
    <dbReference type="OrthoDB" id="198885at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004730">
        <property type="term" value="F:pseudouridylate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1790.10">
        <property type="entry name" value="Indigoidine synthase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01876">
        <property type="entry name" value="PsiMP_glycosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022830">
        <property type="entry name" value="Indigdn_synthA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007342">
        <property type="entry name" value="PsuG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42909:SF1">
        <property type="entry name" value="CARBOHYDRATE KINASE PFKB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42909">
        <property type="entry name" value="ZGC:136858"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04227">
        <property type="entry name" value="Indigoidine_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110581">
        <property type="entry name" value="Indigoidine synthase A-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0464">Manganese</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0015807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="757" mass="81161" checksum="5D17261EC952FB80" modified="2023-09-13" version="1">MLRAGAIPFRRLASANVHCNAQSLTIKNRNGIALMSRPMSAFASLRFSEEVRLALDAKKPLVALESTIISHGMPYPQNFETAIEVEKVVRDNGAVPATIAIIDGQIQIGLSQDQIRDLAKLGRNAVKASRRDLAVVMAKKQTGATTVSATMILAHRAGIPVFATGGIGGVHRGYETSMDASADLTELGRTPVAVVCAGVKSILDIGRTLEFLETQGVTVATYGQTLDFPAFFTRTSGFKSMLKIETPKEAAELIAANHAVDLQSGIVFAVPIPEADAMNDTLVGEAIDLAIKESNEQGIFGKESTPFLLKRVNELTGGNSLKSNIALVKQNASVAAKIAKDLSILIMVIGGTVVDITATAHEASSDSMLNSSFPGTARISLGGVGRNVAEGVSKLHPDGCVFVSAVGGGKQASSTANEKEASDAGDLFGPWLIEEVERRGLHNLEIHMVPGARTATYTALHDVTGNLLSAIADMDVFELLPPTKVKEAIIKHKPSTICFDGNISVECMHTILDTCRGQNIQTFFEPTSVAKCARPLDASMLNVLLEGNLRFASPNEFELQKMAISARKLVSQRRDHLHLKGLHDRPVMEGLHDPADVIAKGGENLAYKGLLLDALSVSQFIPTLFIKLGSEGVLVFQRMTSDIIPKEGTYNNGILQSSICLEDWRKSSIARWHSFPAHKVEDIKSVTGAGDSFVASVVTSLHNLEKTIGACQDRLWDHIDSIIKDGQTAAALTMQTHETVSPTLSQSLQAKRLRSIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXA5</accession>
    <name>A0A9P6MXA5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008549</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000467">
        <property type="protein sequence ID" value="KAG0017172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXA5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="22"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0017172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="50" mass="5418" checksum="9EE6F9B1DAC1C397" modified="2023-09-13" version="1">MDNQFTNPLGDRGRAAEEIYIRQREAEKAAAAAAAKEKAKQEAEKAAGKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXV4</accession>
    <name>A0A9P6MXV4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Yeast cell wall synthesis Kre9/Knh1-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_007784</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000404">
        <property type="protein sequence ID" value="KAG0017920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXV4"/>
    <dbReference type="OrthoDB" id="2156011at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018466">
        <property type="entry name" value="Kre9/Knh1-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10342">
        <property type="entry name" value="Kre9_KNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040269854" description="Yeast cell wall synthesis Kre9/Knh1-like N-terminal domain-containing protein" evidence="3">
        <location>
            <begin position="23"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="Yeast cell wall synthesis Kre9/Knh1-like N-terminal" evidence="4">
        <location>
            <begin position="34"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="145"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0017920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="190" mass="19538" checksum="69B8F942D383C16F" modified="2023-09-13" version="1">MVFSRAIATLATLASALAIAHAAASESGTLAISNPTAGTTWKVGETVFLQWTGECSKTSDKKNVDVNLMTGDSNALRFVTRLASVDCSSSKNIRKEFKIPSQAVAQTGIYSLVVQTTPPSYSNMFTIETANDSASNTDSIADKAATSTTQGGADTTAYQSGATSPLKNARSTGAASTVALAAVFVAAQLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MY20</accession>
    <name>A0A9P6MY20_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphatidylglycerol/phosphatidylinositol transfer protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_008306</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the intermembrane transfer of phosphatidylglycerol and phosphatidylinositol.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NPC2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000446">
        <property type="protein sequence ID" value="KAG0017409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MY20"/>
    <dbReference type="OrthoDB" id="2405630at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032934">
        <property type="term" value="F:sterol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015918">
        <property type="term" value="P:sterol transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003172">
        <property type="entry name" value="ML_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039670">
        <property type="entry name" value="NPC2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11306">
        <property type="entry name" value="NIEMANN PICK TYPE C2 PROTEIN NPC2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11306:SF0">
        <property type="entry name" value="PHOSPHATIDYLGLYCEROL_PHOSPHATIDYLINOSITOL TRANSFER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02221">
        <property type="entry name" value="E1_DerP2_DerF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00737">
        <property type="entry name" value="ML"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040510173" description="Phosphatidylglycerol/phosphatidylinositol transfer protein" evidence="8">
        <location>
            <begin position="19"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="MD-2-related lipid-recognition" evidence="9">
        <location>
            <begin position="22"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0017409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="142" mass="14230" checksum="7E29662E3CA0762B" modified="2023-09-13" version="1">MKFFAATIALVAAAVANAQVTWTDCSSGSDLAVSSMTLSPYPLCIGENVCATITGTLSAPVTSPATLTIIGTYFGTTVYTQSVDLCTVVSCPVAQSTTTLEVCVPVLSNAPAGIPVVLTISATNGNGDTLLCQTGTVTAANC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYQ6</accession>
    <name>A0A9P6MYQ6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Phosphatidylinositol-binding protein scs2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">SCS2_2</name>
        <name evidence="9" type="ORF">BGZ80_007506</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000386">
        <property type="protein sequence ID" value="KAG0018151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYQ6"/>
    <dbReference type="OrthoDB" id="264603at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160219">
        <property type="term" value="C:cortical endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140506">
        <property type="term" value="F:endoplasmic reticulum-autophagosome adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160214">
        <property type="term" value="F:endoplasmic reticulum-plasma membrane adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033149">
        <property type="term" value="F:FFAT motif binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001786">
        <property type="term" value="F:phosphatidylserine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090158">
        <property type="term" value="P:endoplasmic reticulum membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061817">
        <property type="term" value="P:endoplasmic reticulum-plasma membrane tethering"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051685">
        <property type="term" value="P:maintenance of ER location"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902647">
        <property type="term" value="P:negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007009">
        <property type="term" value="P:plasma membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061709">
        <property type="term" value="P:reticulophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000813">
        <property type="entry name" value="Vesicle-associated protein 1-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000535">
        <property type="entry name" value="MSP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008962">
        <property type="entry name" value="PapD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016763">
        <property type="entry name" value="VAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10809:SF6">
        <property type="entry name" value="AT11025P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10809">
        <property type="entry name" value="VESICLE-ASSOCIATED MEMBRANE PROTEIN-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00635">
        <property type="entry name" value="Motile_Sperm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019693">
        <property type="entry name" value="VAMP-associated"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49354">
        <property type="entry name" value="PapD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50202">
        <property type="entry name" value="MSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="238"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="MSP" evidence="8">
        <location>
            <begin position="2"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="136"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="209"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0018151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="260" mass="28892" checksum="36B771D62B0008AC" modified="2023-09-13" version="1">MSIELDPSSQLSFRRPLTEAIKETLIIRNPTQLPIAFKVKTTAPKQYCVRPNSGRVEPGQELEVQVQMQAMKEDPPADFKCKDKFLVQSIAITAEREQLPPAELWPTIEQEAKDQIREKKIRCAFLPPLDATAQGEQNTHNVDASSPTHSFQQSEPAPGHSPSPHTEAIRTGINSSPNSAEVLTLKRELETAQETIHTLRSSIDKLQQETNTLRQRKPESSSSPAPTPSVVHLNQAQVGYPITYVVGAAVVAFLFAYLFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYS7</accession>
    <name>A0A9P6MYS7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MutS protein msh5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">MSH5_1</name>
        <name evidence="7" type="ORF">BGZ80_008316</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA mismatch repair MutS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000447">
        <property type="protein sequence ID" value="KAG0017392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYS7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051026">
        <property type="term" value="P:chiasma assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361:SF20">
        <property type="entry name" value="MUTS PROTEIN HOMOLOG 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair proteins mutS family" evidence="6">
        <location>
            <begin position="1"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="123"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="144"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="182"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0017392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="229" mass="25168" checksum="1C40311B91C7D639" modified="2023-09-13" version="1">MAHIGSFVPAESAVIGLTDKILTRLQTRETVSSIKSAFMTDLQQVIVALDMATNRSLVILDEFGKGTTSTGLYLSKLFQRYETIVPMLTEHEKSMQKMYEQLTSMILSLDLDRDIIENKELTTAAPNREGSHSIHQQADFADPNGSTSDVVAINKGNTVNGKMSNIETGGKPQNREEQGELLCDDGDDGGDDDGNYGGSGNEDSWYKAIDQLLRFAAKVDRKEREAEQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZ08</accession>
    <name>A0A9P6MZ08_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mitochondrial protein fmp25</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007683</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000398">
        <property type="protein sequence ID" value="KAG0017985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZ08"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034551">
        <property type="term" value="P:mitochondrial respiratory chain complex III assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053245">
        <property type="entry name" value="MitoProcess-Associated"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47563">
        <property type="entry name" value="PROTEIN FMP25, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47563:SF1">
        <property type="entry name" value="PROTEIN FMP25, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13540">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="RCC1" evidence="1">
        <location>
            <begin position="346"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0017985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="587" mass="62431" checksum="EF529BFA26F5B1C7" modified="2023-09-13" version="1">MLRIGQHGGRRIISRAASIPSVIPSSTRHRFITTHARNDKISWTPSTTWFLGAGVVFTGVSLVLQSPSLGLSDCAVQNESPSSDPGKSTSLGARLAGYFSKKPQPIDQKDIVLDTDLTVTSWKQLEQASLVKVPGVVLWGSNKTGLIDPSGKSPGVIQIPQRLDAFQGTVLRDLKLGEDIAAAVDDQGDVYQWGSGYSSDAHQPEITLKNRDISSVALGDSKLFGLSKDGTHVYVMPKTRPTSGPTKAAIDYNPSSGGVLKYVGLAGNAHDSMTQLPVKDILQKGETITSFASGKNHLLMVTSEGRVLGSDDGLSVSLIGDADFRESRILEVACGEVHSLARDDQGRCWAWGTNGFGQLAQGAYSHANLRLTQPTLVKDIPGTAGSAECVKVAAGGNTSYVVIYQQNRFKVKSAGMGQWGQLGDGTVNKEAEKKLMPIGIHDLVIGSTHAFAVLDNAIDERTASSDDVVNHGRDVLSWGQNTYFQLLTGKRINRTEPIYALPLDSEILQPADKAIAAISQGGTPKKDTRGPDEATALTPTNRLQLLPAQNRNDVTSGKKGAKGDGEKVELKVVAGNGISAVFCKSVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZ94</accession>
    <name>A0A9P6MZ94_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminotransferase class I/classII large domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007236</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000367">
        <property type="protein sequence ID" value="KAG0018381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZ94"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43799">
        <property type="entry name" value="AMINOTRANSFERASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43799:SF1">
        <property type="entry name" value="ASPARTATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="1">
        <location>
            <begin position="120"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0018381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="346" mass="39136" checksum="2352BB239C22CCE5" modified="2023-09-13" version="1">MSAAANTTVWDTKTQQFHGGQDWKFLDNFVEDFSVTTNCLGTPVKAIQAARDAVATCHHYPPANQEPAKSSLAEWIWPEHWEANRDRLLLGNGASELIDLVIRSAPQGSWKAGPWDVQDKANVVCIVNPCNPTGDYKSVDELKSWILNNVQDNGVVVIDESMQIWVGPEFRQDSMTAQTEFLEKTFKERNISIYVIHSWTKIWSCTGLRLGSIVCPTVAHCVELKRIQVPWSVNSPALAFLNEVVRDTEYLEETWRVTPIYRAQLIERLTALANGRSWEYFGKPYLSWVWADLKDVETAEKAVALAKKAGVPVRSGKPGYERPTFVRIAVREPKQTDVLFSAWKDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZY7</accession>
    <name>A0A9P6MZY7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006317</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000311">
        <property type="protein sequence ID" value="KAG0019094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZY7"/>
    <dbReference type="OrthoDB" id="2425257at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="270"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="487"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="24"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="351"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="381"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="406"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="493"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0019094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="507" mass="54471" checksum="CC5214138754A11D" modified="2023-09-13" version="1">MDSAYSETLIASETADASAVVASTPTSTSIPSPSIQNTPILTSNNVDDTANNSGNSGMDFFFAQVPTDSDWLRGATELDIRLSPVLQDRIAQSCLIKMQQASSGRESLQRLAQLSRFWRRLQTEMLSMPMFTAPQVPAPLDQWFAEFAASSPEASSSLMQGLSTDFNWNLDLLVSSSPPSSNGLMGYELGSLWNIMDSQDFASTVGSDNYSLPLPTPSSAILPSSEPIDQSLAEVVAATAAVDGASSSSAMLQDSRMNSIQAGPVVTSIPETLPASSNTTAWSNDGPMNYRTETSISIDDSQGLPKDDYTNSEVTSMDVDLPMQDMTLTSPPPSLPSKTRKKPASNQRRATIPRKAKRTVRRQPRKLSKESLSFKARLASEIEENESDEDVLEHADRNKRRRGSKDSSSSSDSGPESAPGSPQTPPSTYDGLNAAAAASEQSPSGNGDVSEPLFAVAFQETILSSDKTSHMSAAVAVEDLVNLKRLEEEESHSSFQRRPSTRAFGQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N003</accession>
    <name>A0A9P6N003_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_006456</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000319">
        <property type="protein sequence ID" value="KAG0018986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N003"/>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050403">
        <property type="entry name" value="Myosin_RLC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23049">
        <property type="entry name" value="MYOSIN REGULATORY LIGHT CHAIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="10"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="46"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0018986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="84" mass="9371" checksum="6EEAC7C1D8ADE3BD" modified="2023-09-13" version="1">MATNSGFSAQEVQELKEKFTTFDTNNDGRVDASELLELTKTLGETATQEELDFVLKSFDKNADGGLDFTEFLELMNTLRSVGRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0T6</accession>
    <name>A0A9P6N0T6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">EKC/KEOPS complex subunit CGI121</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">EKC/KEOPS complex subunit cgi121</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_004252</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. CGI121 acts as an allosteric effector that regulates the t(6)A activity of the complex. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators. CGI121 is not required for tRNA modification.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the CGI121/TPRKB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000219">
        <property type="protein sequence ID" value="KAG0020401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0T6"/>
    <dbReference type="OrthoDB" id="329139at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000408">
        <property type="term" value="C:EKC/KEOPS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2380.10">
        <property type="entry name" value="CGI121/TPRKB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013926">
        <property type="entry name" value="CGI121/TPRKB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036504">
        <property type="entry name" value="CGI121/TPRKB_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF011465">
        <property type="entry name" value="PRK14886.1-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15840">
        <property type="entry name" value="CGI-121 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15840:SF10">
        <property type="entry name" value="EKC_KEOPS COMPLEX SUBUNIT TPRKB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08617">
        <property type="entry name" value="CGI-121"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143870">
        <property type="entry name" value="PF0523-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0819">tRNA processing</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0020401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="176" mass="19459" checksum="168CD71503591FB6" modified="2023-09-13" version="1">MESYPIDVVPSAGSIQMACFITVKNAADLKERLLEQDKTLTFAMVESNLIMDVFQLLLAATKAAQDNETGKLSTQSLSSEIIYNLSPSKNIAESLKRFGITEDTTSLIAVKIGGDPDEVLEDMSKTVDGILVSFSKLDQEKDMSKLRQYYKIDPKVTDDKAILNWIIGAMAMKNIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0V9</accession>
    <name>A0A9P6N0V9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004137</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000214">
        <property type="protein sequence ID" value="KAG0020479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0V9"/>
    <dbReference type="OrthoDB" id="6159439at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="327"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="15"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="176"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="333"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="356"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="401"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0020479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="412" mass="44599" checksum="A9E366D6DB028047" modified="2023-09-13" version="1">MRSRQAASNPAQKNPLSIGGHPGSHSPTPPRVFGSQVDKPIKRATRPLECSNCMALDSISWRSKADLRISETEDMTSSAETATSDGPHDEGSKLLCPACTQYSRAHGRPRPVPPFRTNFLKKIHTRFKRELQDVRFQGWQDAQILEIEDRMVEREFQIVFNGLDESDAFQNPNQRPSASKSPGPSASLKATVSESSSSGKDTLAKENSTSESTSLSSKGAEGIIIKIEDDDSTASIQKLKPDNVEVRTFQSEASVGELFGQRWRTEPVVGYTLVHFGGSDRTRMVPMNPTVPSLTVTFNRSDETITFAFRVLVNGLCLLSSGGGPPALHMPEMADDEESEGETEVVVVPDNDKDGSSPSPTTTNAAAAPSDGKPDTPTLINPELERAAVSLIQKSTSVDEPESKDTNSAEQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0Z7</accession>
    <name>A0A9P6N0Z7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13">General transcription and DNA repair factor IIH subunit TFB4</fullName>
            <shortName evidence="13">TFIIH subunit TFB4</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12 13">RNA polymerase II transcription factor B subunit 4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">TFB4</name>
        <name evidence="14" type="ORF">BGZ80_003923</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Component of the 7-subunit TFIIH core complex composed of XPB/SSL2, XPD/RAD3, SSL1, TFB1, TFB2, TFB4 and TFB5, which is active in NER. The core complex associates with the 3-subunit CTD-kinase module TFIIK composed of CCL1, KIN28 and TFB3 to form the 10-subunit holoenzyme (holo-TFIIH) active in transcription.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the TFB4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000207">
        <property type="protein sequence ID" value="KAG0020607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0Z7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000439">
        <property type="term" value="C:transcription factor TFIIH core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005675">
        <property type="term" value="C:transcription factor TFIIH holo complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004600">
        <property type="entry name" value="TFIIH_Tfb4/GTF2H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12831:SF0">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12831">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIH TFIIH , POLYPEPTIDE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03850">
        <property type="entry name" value="Tfb4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 13" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10 13" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 13" id="KW-0804">Transcription</keyword>
    <keyword evidence="8 13" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="7 13" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 13" id="KW-0863">Zinc-finger</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00033341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU368090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0020607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="259" mass="27997" checksum="7965E7B43908F6F8" modified="2023-09-13" version="1">MKDSATSEGRSIGGRITGYQYAKECMHDSNLLVIVIDTNPFEWEHPSAPLKLNEALQHILAFMNAHLAGRHDNKLAVIASHVGVSKFLYPTLNEATPGSKVQTKKDANVYQVFKVINDAVLLGITKLLEDTSPTLEEKDLGSSKIAASLSLGLCYINQALKSDGMGHLKPRILVLTVSPDSSSDYIPIMNCIFSAQKADQVCFPTSATIKATGSKDGGLKSWLSSSKYTNTDGDIREANTIKYGGVSKIHSPFASHINS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2Z8</accession>
    <name>A0A9P6N2Z8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Frag1/DRAM/Sfk1 family-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_009809</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000062">
        <property type="protein sequence ID" value="KAG0023315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N2Z8"/>
    <dbReference type="OrthoDB" id="68581at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.10.10:FF:000031">
        <property type="entry name" value="Calcofluor white hypersensitive protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019402">
        <property type="entry name" value="CWH43_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057315">
        <property type="entry name" value="Exo_endo_phos_PGAP2IP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051916">
        <property type="entry name" value="GPI-anchor_lipid_remodeler"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053912">
        <property type="entry name" value="PGAP2IP_TM_1nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053911">
        <property type="entry name" value="PGAP2IP_TM_2nd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14859">
        <property type="entry name" value="CALCOFLUOR WHITE HYPERSENSITIVE PROTEIN PRECURSOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14859:SF1">
        <property type="entry name" value="PGAP2-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23022">
        <property type="entry name" value="6TM_1st_PGAP2IP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23021">
        <property type="entry name" value="6TM_2nd_PGAP2IP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23226">
        <property type="entry name" value="Exo_endo_phos_PGAP2IP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10277">
        <property type="entry name" value="Frag1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="175"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="204"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="269"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="296"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="452"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="490"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="515"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="540"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="570"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="605"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="643"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="domain" description="CWH43-like N-terminal" evidence="2">
        <location>
            <begin position="19"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="PGAP2IP first transmembrane" evidence="4">
        <location>
            <begin position="273"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="domain" description="PGAP2IP second transmembrane" evidence="3">
        <location>
            <begin position="450"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="domain" description="PGAP2IP C-terminal nuclease-like" evidence="5">
        <location>
            <begin position="677"/>
            <end position="914"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF23022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF23226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0023315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="959" mass="106895" checksum="B05E38BD99BEA1C8" modified="2023-09-13" version="1">MASAGDKKGIVLARIPGTSIPLAHTIFGASAFILAFVIGCYGHYYKIVKNGVAGYPDEWFPSVSATTGDWYPERNICQIFIALTSGPRLMLCYLWYLLTVRNIPANGSKGFAKFLFTNDVIRTVACGGWVYITSSDDHDIHDIAMIVYLLCTIPHVVGTIKTAPQIPKAQQYRKLFAYTFFGALVPMVHFFIQHNVHRIPGAYTYYAFFEWSLIISDLAFDAVALIDFNTLEFRIVDVGTNGHRDLKTYGGSDSAAFSPFEVVSFAADVYLGFVFWSMLTALPLMIWYFPLWHMGISGYEAFLFCNLSAVLLGFNFLRRGIEKAKGFVHLLSLVGVLSYKIADPAHRLMAVAAGVSLSLLTWGATLFGQRRQNGRAERGVLTLALGLILHNVVKQAWWANNPIWPIMNENTGGQNMIGLALGVLASLQVMLRKDPGADEPPASQTGKHGESWFLAAIGAGGYLFCLHSMFTDSTTISRWSLGGYPNTGPQPVPGGLMVIAAMAAGLTLSSKRRWVTSLIWWAIGTAGLAGLHFVEGDVGFAGGIVFTVYILSLFPTLFRSLTRQPPGRTFFLAMLVYNLLALAHVWVVAYAFVPGGEVMREHTDYVLIAMQTCLLIGVFNANSSAWSAITEARAQAAFSSARLYSKLSLVGLMIASIGVCYNRLPKSTPQPYHPEHKLITAGIWTIHFAIDNDMYNSEIRMRDAIRDLELDVIGLLESDLQRMIMGNRDLTQFLSEDLNMYADYGPGPTKHTWGCTMLSKFPIKRSSHHLLPSPKGELACAIHATLDVYGKEVDVIVSHNGQEEDLLDRRLQTTELGRIMRESDNPFLFLGYVVTKPGQGQEIYELLMDGGHVHDIEVSDWDRWCQYLAFRGVKRVGYARISHGGITDTEIQVGKYQLLDEHPTSWDRSQSIESFKKEETYAQISEDQVPEGMRFPPKFYGQGVRKHRFHVFDRPYYYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N311</accession>
    <name>A0A9P6N311_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_001448</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Iojap/RsfS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000133">
        <property type="protein sequence ID" value="KAG0021907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N311"/>
    <dbReference type="OrthoDB" id="21330at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090071">
        <property type="term" value="P:negative regulation of ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01477">
        <property type="entry name" value="Iojap_RsfS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004394">
        <property type="entry name" value="Iojap/RsfS/C7orf30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00090">
        <property type="entry name" value="rsfS_iojap_ybeB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21043">
        <property type="entry name" value="IOJAP SUPERFAMILY ORTHOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21043:SF0">
        <property type="entry name" value="MITOCHONDRIAL ASSEMBLY OF RIBOSOMAL LARGE SUBUNIT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02410">
        <property type="entry name" value="RsfS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="331"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0021907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="364" mass="41096" checksum="47ED278389860E9C" modified="2023-09-13" version="1">MFRASLSRSGRYLWSSATRRAAIPSAHIKIRQHVLQLDPRTSRVCYSTTSALFRKYESHHDHVNINKSTSSALGAYSAEDLVEDNQKDHLLDHDDHIGDHDGVETIDPKDFPELYPENNIEGANQESTASVLLSEKERSEEEFSWFVDESYPEKVGENKDSLGSSSAPSSDFVPLWQKNAQRSQSGSVETHMDGNQPQFWEHSADSISGLVALIESERAKNVKVIDMRDKCDWTDWMIVAEGLSERHLGNVADEVYSALKKSSPKTSPPVMEGRDTTDWVVIDAGSVVIHFMTPEARKERDLEGLWASVKNPLKIKDVEDITWDDVKGKMTKSWKENTGRSRGEDGKRGRRGERDIPLAEVVKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N333</accession>
    <name>A0A9P6N333_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein bL28m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_009466</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000057">
        <property type="protein sequence ID" value="KAG0023427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N333"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.170.40:FF:000003">
        <property type="entry name" value="54S ribosomal protein L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.170.40">
        <property type="entry name" value="Ribosomal protein L28/L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00373">
        <property type="entry name" value="Ribosomal_bL28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026569">
        <property type="entry name" value="Ribosomal_bL28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034704">
        <property type="entry name" value="Ribosomal_bL28/bL31-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037147">
        <property type="entry name" value="Ribosomal_bL28_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053045">
        <property type="entry name" value="Zinc_cluster_trans_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31986">
        <property type="entry name" value="REGULATOR OF DRUG SENSITIVITY 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31986:SF7">
        <property type="entry name" value="REGULATOR OF DRUG SENSITIVITY 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00830">
        <property type="entry name" value="Ribosomal_L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143800">
        <property type="entry name" value="L28p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="214"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="216"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0023427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="245" mass="27562" checksum="F39FCD36C8BE002C" modified="2023-09-13" version="1">MGTFRPAFRAVAQSLTDIDLVLVEEAFERLLLDYDRVFSSMGIPACLWRRTGEIYKGNKEFAALVNVPLEMLREGRLCIYELMAEESAVNYWEKYGNIAFDAGQKAVLTSCLLKNPDPESKQIQFGNNVPFSKTKTRRTWLPNVQTKRLFSETLNDWIRLNMTTSVIRTVDKKGGLDRYLLETRPDLLGAKGMELRGKIVEALKAKQAKKALKNYTNTQQQNSSTLLSSEAQAPAKSAATKTASP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3G5</accession>
    <name>A0A9P6N3G5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_000614</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000113">
        <property type="protein sequence ID" value="KAG0022280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3G5"/>
    <dbReference type="OrthoDB" id="2449556at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="417"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="545"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="420"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="507"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="557"/>
            <end position="610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0022280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="629" mass="72244" checksum="44599F19EE868414" modified="2023-09-13" version="1">MEPNNDLNQIASTTPEISSPSSSPPQPEPQPDEEQYNDEFDDIFEPRDSIDRINTPPTTSVALPPRNHTQVFMPSLPPTSSSRIVVSTPEESTDVAADTSSINEITKEQLTAELLAVLPQPLPFRPVYKKRTVLPAAGSDGIIRKSGTLAALEKQLLERLPHDRKTQPNTNIYDRPPSPPPPPPVQQPDAPPHEHQLLLEQLLKPKKRRRKKKDPKPPREIKPKKPPTIWVPASETRRVKTFKPSRRSKIHGLVQPINIDRLVKLQQSYNKRISSLTKKPLPLRELQKLVETELEEEELVLRELGNLLHREYLKLQLEEGVLINMLKLSQSGALDETDLVHLRPRTKWTKKELQDMAREKARAEKMRAKRARDLRKRGGILPLASDLETNRVGDMAVVQLESANNYEFNIVMGRRRNEGYDDDYDGEEEHEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEDDDDDDDDEEDEDEEDEEDEESRKPRYSLPGESYTSRPLASTSLGGSSIGRPGASISKSYDSLGAIKELVTHKSKKRKLQSQDEPDNYDDDDEIELYDSVDDEDAYSGSEEEYGDEYDDEDDEDSDDEQEEEEEDDAKARETLLRMLSIYGTGSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3H3</accession>
    <name>A0A9P6N3H3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ubiquilin-4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">UBQLN4</name>
        <name evidence="4" type="ORF">BGZ80_009926</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000064">
        <property type="protein sequence ID" value="KAG0023272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3H3"/>
    <dbReference type="OrthoDB" id="267397at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031593">
        <property type="term" value="F:polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16106">
        <property type="entry name" value="Ubl_Dsk2p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.260.100:FF:000001">
        <property type="entry name" value="Ubiquilin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006636">
        <property type="entry name" value="STI1_HS-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015496">
        <property type="entry name" value="Ubiquilin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10677:SF3">
        <property type="entry name" value="FI07626P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10677">
        <property type="entry name" value="UBIQUILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00627">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23195">
        <property type="entry name" value="UBQLN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00727">
        <property type="entry name" value="STI1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="3">
        <location>
            <begin position="13"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="2">
        <location>
            <begin position="439"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="241"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="297"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="368"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="299"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="368"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="378"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="401"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0023272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="483" mass="52423" checksum="45FF3940D51D6375" modified="2023-09-13" version="1">MEESESNIPQQAIVLTIRPSTGSTFTTTISTESTVRQLKEKLATLELPATSIRLVYSGRVLKDEDQLSVYSIKEGHTIHMVKGASNRANEQAVQTVRPQSNNSASGPEGFDEQGLMATLLDNPAIRDMMANPEVVRRMMMANPQTREVMENNPEVAQMLNDPSFLRQSLDMARNPKLMKQALRNNDRALSNLEMIPGGFNHLRRMYHSVQEPMEASRSAPEPSTDDLNAQFAARLNADTRPHAGELNTTPLPNPWAPPRQNNTSRPSPMFPGMPGASRNSSGGMSAFNLFANPFAGLETPSTGATGQPGSTQTPPNPFSAMMNQRMGGLGGGPQANPFGLQGMGEGFPPMGNNPEMFQQMMQFQQMMRQMQQQQQQQPISQPPMTGLPSLTNIFRGVPPLADSTNSSNTSSTNSGTATNTTDSTGNSTATATSAASTQQLEERFESQLASLRDMGFSDNSRNVRALLASGGDVHSAIEFLLRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3I4</accession>
    <name>A0A9P6N3I4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Proteasome inhibitor PI31 subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BGZ80_000220</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Plays an important role in control of proteasome function. Inhibits the hydrolysis of protein and peptide substrates by the 20S proteasome. Also inhibits the activation of the proteasome by the proteasome regulatory proteins PA700 and PA28.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the proteasome inhibitor PI31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000104">
        <property type="protein sequence ID" value="KAG0022448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3I4"/>
    <dbReference type="OrthoDB" id="68090at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004866">
        <property type="term" value="F:endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070628">
        <property type="term" value="F:proteasome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1000.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045128">
        <property type="entry name" value="PI31-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013886">
        <property type="entry name" value="PI31_Prot_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021625">
        <property type="entry name" value="PI31_Prot_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13266">
        <property type="entry name" value="PROTEASOME INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13266:SF1">
        <property type="entry name" value="PROTEASOME INHIBITOR PI31 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08577">
        <property type="entry name" value="PI31_Prot_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11566">
        <property type="entry name" value="PI31_Prot_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0007">Acetylation</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4" id="KW-0488">Methylation</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-0647">Proteasome</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PI31 proteasome regulator N-terminal" evidence="13">
        <location>
            <begin position="56"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="PI31 proteasome regulator C-terminal" evidence="12">
        <location>
            <begin position="295"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="211"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="377"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="220"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="256"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF08577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF11566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0022448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="16">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="428" mass="44475" checksum="DA37A3CA25FDD71B" modified="2023-09-13" version="1">MSNLQQSPTSGGTGTSNNVLDCDSVLDLLQALLVTSSSSTATSTSEPTSTTSVTILNSPYEGLAALSHAIMTAVGFRLVGLGEDDSLGSDRLNIEDLKKANVLPQRWNASSESFSFRYTHSHSQLTYLIKCMRLAGKFVIHGTTIETSKICSLELEVKDFTSPSYFPYTTTTNLSTDPLWNGFLSRSRINDLIMQFKLKIVQVLIPGLSKPGYEEERTPADNTQTSADNTQTSRDGNTRGGFGPEYYPDDPSTFPGIGGIPRPGGRGSVPIFGDPFSAESSDYMGMGGGHNPFDIGRSDLDPFGGRLGGGFGGGGGFGGGIGGSTGGGMVVGPNHPMFRRPPGGVGGIGGEGGIYGGPQPLPRGSVPPGARFDPIGPFGPTGGNAPGAGTAHGDPYRGQGRGAGRGASFPGEPDNDEAPPPGYMDMFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3T7</accession>
    <name>A0A9P6N3T7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BAG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_008791</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000049">
        <property type="protein sequence ID" value="KAG0023619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3T7"/>
    <dbReference type="OrthoDB" id="333905at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.120">
        <property type="entry name" value="BAG domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036533">
        <property type="entry name" value="BAG_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003103">
        <property type="entry name" value="BAG_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02179">
        <property type="entry name" value="BAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00264">
        <property type="entry name" value="BAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63491">
        <property type="entry name" value="BAG domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51035">
        <property type="entry name" value="BAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BAG" evidence="2">
        <location>
            <begin position="244"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="14"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0023619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="302" mass="35056" checksum="72C4F0E99065859B" modified="2023-09-13" version="1">MGQRPQRRQERQNFFPSFSDSFFDPFTSEDPHSDSYYGIPNTYKQAPHRQQYQPQRAGQHQPVDEYQDDDEVEQTQYRPEHRTQYRQRPQQKQQQRPNQQPQSHAASRRRSRRHRKRDTQDPQDLQTPVSHIHPQASNAQADEMESLVQAAFGDEEESARIKSEPKNEVRESRPYEEDSLEQDEQEEEESGESGESGESEGEQTLPDRELQQKSSAELEQIESSLEGLSNELDQIISGEITKKKQILFTEENLTKAMLKIDAVESGGDPSIRQKRKDLINQAEGLLEKVDEFKRLTNTSATN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N443</accession>
    <name>A0A9P6N443_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">threonine synthase</fullName>
            <ecNumber evidence="4">4.2.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">THR4</name>
        <name evidence="12" type="ORF">BGZ80_010224</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 5/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the threonine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.1" evidence="4"/>
    <dbReference type="EMBL" id="JAAAID010000069">
        <property type="protein sequence ID" value="KAG0023164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N443"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004795">
        <property type="term" value="F:threonine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01560">
        <property type="entry name" value="Thr-synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000024">
        <property type="entry name" value="Probable threonine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1380.10:FF:000003">
        <property type="entry name" value="THR4p Threonine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1380.10">
        <property type="entry name" value="Threonine synthase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000634">
        <property type="entry name" value="Ser/Thr_deHydtase_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029144">
        <property type="entry name" value="Thr_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037158">
        <property type="entry name" value="Thr_synth_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004450">
        <property type="entry name" value="Thr_synthase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051166">
        <property type="entry name" value="Threonine_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00260">
        <property type="entry name" value="thrC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42690">
        <property type="entry name" value="THREONINE SYNTHASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42690:SF1">
        <property type="entry name" value="THREONINE SYNTHASE-LIKE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24857">
        <property type="entry name" value="THR4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14821">
        <property type="entry name" value="Thr_synth_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00165">
        <property type="entry name" value="DEHYDRATASE_SER_THR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 9" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0791">Threonine biosynthesis</keyword>
    <feature type="domain" description="Threonine synthase N-terminal" evidence="11">
        <location>
            <begin position="2"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="Tryptophan synthase beta chain-like PALP" evidence="10">
        <location>
            <begin position="94"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="9">
        <location>
            <position position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR604450-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF14821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0023164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="523" mass="58125" checksum="9383CCC4438C6D83" modified="2023-09-13" version="1">MKYKSTRGKASNYTFEQAVLAGLSPDGGLFIPESIPQAPADFLTKWASLSFQELALEILSLYIDDTEIPRNDLKELIERSYSTFRHKDITPLHQVKDGLYILELFHGPTFAFKDVALQFVGNLFEYFLKRKNAGIENKADRHKITVVGATSGDTGSAAIYGLRNKQDLEVFILFPTGRVSPIQEAQMTTVLDKNVHNVSVRGTFDDCQDIVKGLFANKDFMSKYNLGAVNSINWARILAQTVYYFHSYFSLLRALNLKAGSEEASKIRITYSVPTGNFGDILAGYYAHQMGLPTSKLLVATNANDILYRFFCSGVCEKIVGEDGGVHETLSPAMDIVVSSNFERLLFYLARDIAVDASVPESEKDVKAGEIVNGWMVDLKQKGRFDTGSKVLAEAKRIFDAGHVSDQETCDTIREYSFPAEASQAPYVMDPHTAVGVTAARTVVPETNSQNIVIALSTAHPAKFAEAVERAVKDQEGVQFEEFFKKVSPKEFDRLTTAERRVTLIPRADEALVIEVIEKELSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N5G0</accession>
    <name>A0A9P6N5G0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12 16">ADP-ribosylation factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">BGZ80_004770</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.</text>
    </comment>
    <comment type="function">
        <text evidence="16">GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 16">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the small GTPase superfamily. Arf family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000024">
        <property type="protein sequence ID" value="KAG0024256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N5G0"/>
    <dbReference type="OrthoDB" id="2011769at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04150">
        <property type="entry name" value="Arf1_5_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:003500">
        <property type="entry name" value="ADP-ribosylation factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045872">
        <property type="entry name" value="Arf1-5-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024156">
        <property type="entry name" value="Small_GTPase_ARF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11711">
        <property type="entry name" value="ADP RIBOSYLATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00328">
        <property type="entry name" value="SAR1GTPBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 16" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8 16" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 13 15" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="10 16" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 16" id="KW-0519">Myristate</keyword>
    <keyword evidence="5 13 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 16" id="KW-0653">Protein transport</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 16" id="KW-0813">Transport</keyword>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="24"/>
            <end position="31"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="126"/>
            <end position="129"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00053326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00070396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU003925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU369003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0024256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="181" mass="20691" checksum="A51633F53C1EF23A" modified="2023-09-13" version="1">MGLSISKLLSGLFSKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGIIFVVDSNDRDRITEAREELQRMLNEDELREALLLVFANKQDLPNAMNAAEITDKLGLHSLRNRHWYIQATCATSGDGLYEGLEWLSNNLKRRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N752</accession>
    <name>A0A9P6N752_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001721</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000014">
        <property type="protein sequence ID" value="KAG0024529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N752"/>
    <dbReference type="OrthoDB" id="421226at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050648">
        <property type="entry name" value="F-box_LRR-repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13382">
        <property type="entry name" value="MITOCHONDRIAL ATP SYNTHASE COUPLING FACTOR B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="2"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0024529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="353" mass="38489" checksum="CCC815C6B497CFD0" modified="2023-09-13" version="1">MELLPTELLLTIVDFIVFDQATLASCSRLNRRWYYLIRDLLYKKPKLIRQSAFGAFLRTVDTPEMSQYLQSIGDGSCKDIQNLFRSSSSLRPIISASSQAHIDILSAKKPTATRSIMNSPKLFPAAILTSTPPGALVETVDLSMLPHRWETVDFGSIQSLTQGCPYISVLDLRDCVILRDSAVQLIAEHLGPRQLRSLVLSGCSKITDLAVLSLCAHATGLENLELSGCDRISDISVLELGSITAQATPTALDTFSAISESKIYKEGLSDIELTKPFSSQSISKSIKSLDLSYCTRITDTGIKGLQMGATGLTSLNLEGCYGVLMGGDDLDMNGWEDLDEDDEGLVSDLDADY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SR81</accession>
    <name>A0A9P6SR81_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_008546</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004666">
        <property type="protein sequence ID" value="KAF9992451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SR81"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9992451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="127" mass="14653" checksum="ED9FCA2150ED97A6" modified="2023-09-13" version="1" fragment="single">MITHPPMESPLLNYVQNKPDVETPLRKLKRERLKGRGGDVYISPRAKATPRATDHFDLTVKVQEFLASDRKVFLLLGDSGAGKSTFNRALEISLWDNYRMNGRIPLFIHLPEIEKLERDLVAERLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SRS7</accession>
    <name>A0A9P6SRS7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Mitotic checkpoint protein bub3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_007799</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004058">
        <property type="protein sequence ID" value="KAF9994472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SRS7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10971">
        <property type="entry name" value="MRNA EXPORT FACTOR AND BUB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="84"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="147"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="176"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9994472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="185" mass="20672" checksum="214D66A1174B137E" modified="2023-09-13" version="1">MAERLVFIYDLRNMKETLQRRESSLKYQTRMVRCMRDGLGYASSSIEGRVAVEFFDPSAESQAKKYAFKCHRKQIDGVETIYPVNALAYHPIHGTFASGGSDGGVTLWDGFNKKRLRQYNPYPTSISSLSWSCDGKTLAVASSYTFDEGEKDHPPDQIFLRSISDQEARPKTLPPSSASSAALGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SS17</accession>
    <name>A0A9P6SS17_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007612</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003928">
        <property type="protein sequence ID" value="KAF9995068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SS17"/>
    <dbReference type="OrthoDB" id="2430134at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="242"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="245"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9995068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="295" mass="31769" checksum="C2F7B3FC55B83F6F" modified="2023-09-13" version="1">MATSIISPVEDQSILALAPTVKDIPSEATSTQLDTQHDEPTQFDPLATNTSVPSSDDDDDQVESADDGTDTVIGNTNTIVTQENSNAIFATTAAAATDSTLATTTTTTTTTITATAVVAASEEAVEVKDNDTITKESKVEETTAETPESITAPEPKDENIQSTVVPPQPQVVAKEADETKKEVLKTKGEEVEKQIKATPEEVKTIERGDDEPLKSLSRPVSRQDLRRKSSFFNSKDIAVSDRRYSNYSSSSTSSSYSNTSGTSSLVAPSLRPIVDPRYKSRFQNTLAQWRARASN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SS44</accession>
    <name>A0A9P6SS44_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">WD40 repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_007526</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003877">
        <property type="protein sequence ID" value="KAF9995376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SS44"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.80">
        <property type="entry name" value="E3 ubiquitin-protein ligase SopA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848:SF8">
        <property type="entry name" value="F-BOX AND WD REPEAT DOMAIN CONTAINING 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141571">
        <property type="entry name" value="Pentapeptide repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="428"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="470"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="182"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9995376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="497" mass="56294" checksum="203307C6E1CCB36E" modified="2023-09-13" version="1" fragment="single">LRKPLWKIEDYQQALDQIPNLQDLVKNPFLLKLTLEVLPRLFDKDPEFSTTHITRVELYDEFVAQWIERSQKRLREMELSPRDKEAFKMLSDANFKQHGIAYLKDLATAIYDKQGGNPVINYSERLDHKTWKKTFFDNNDGKNLLREAIPLVRNNDQHRFIHKSVLEYGLSLAVFDPSTRKEITEAESRPSRRGSTSSTLSFETPDLVEEPAIAIEQALLESPFGRRSFVNEPSISQFLVERVQQESVFKEQLHAVIERSKTEKTARIAAANAITVLVRAGVQFNESDLRGIKIPGADLSYGIFDSARLDGADLRKTNLRTIWLRKANLSGVDMTGVQFGELPLLQEDDTVIQCAYWYDGKTLAVGLKNGGFRLYDTSNWEKIKEFEAYDDQKGWLLFSETSDRVAYRALGYVLRLVDVKTGNYFQTLQGHTSFTNSVVYSPCGSKVASGGGDKTVRVWDVDSGECIHILQDHGEMVISLAYSPSGGQIASASGDWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWH2</accession>
    <name>A0A9P6SWH2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003436</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001907">
        <property type="protein sequence ID" value="KAG0008446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWH2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052945">
        <property type="entry name" value="Mitotic_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43628">
        <property type="entry name" value="ACTIVATOR OF C KINASE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43628:SF1">
        <property type="entry name" value="CHITIN SYNTHASE REGULATORY FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="21"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="20"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="233"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0008446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="971" mass="108923" checksum="54F3FAADE19CAEAB" modified="2023-09-13" version="1">MYWNGYGVTQDDSKAVEWYQKAASQGDTAAQNNLGFMYRNGYGVAQDYSKAIEWYQKAASQRDAAAQTNLGLMYENGYGVPKDISKAIELWEKAAAQGNNGARLNLERERPQVGAMSKRNDELEGWRNGDKDRTKKAIERRRKTVQEITDPRPNGRFSFCINMSETKSLGHLQALHFDVKHDKLYIAWSDAQDVTIETQEIIAGIESLKIDCPPAPIATTPDIQFEQHHSLDARPIVDSSPSPVSENNRNKDNRNNRVQRTCDEPFESRLLSTFGVSNLVEGFEKAAHEGDPKAQYCLGFIYLNAPGSSRDYIKAFHWLERAATQGHSSAQNNLGVMYRDGYGVTQDHTVAYGCGVDQDYSRAVELFQSAAMKGNADAQSHLGYMYQHGRGVDQDFSKALKWNQKSANQGYARAQANLGYMYLKGQGVAPDYTESVKWYLKAASQGLARAQNELAYMYRDGIGVSPDYSKAAEWFWKSADQGFANAQLNLGFMYQYGRGVTQDYLKAAKWYRKAANQGNSEAQSSLGFLYLNGHGLTQDYSKAIEWFQKSAMQGDARAQCNLGFMYRKGQGTTVDYIKALEWHQKAADQGYPKALNELGFMYQNGHGVAQDYTKAAKLYQKAASRGYAAAQYNLGFLYRDGLGVSQDYTKAIKWFEKAAIQGNAAAQLNLGFLYNHGRGVPQNNFKAAEWYQKGANQGNAECQSRLGFMYQKGYGVMKDQYQAFGWYQRAANQGNPRAQNELGYMYRKGYGVSQNYTKSVEWFQKAAKQGYADAQNSLGLMFRRGHGVPQSYTKAAKWYQKSASQGNPHAQTNLGYLYQHGQGVLQDYSKAMMWYERAARQGDADAQNNIGYMYQNGQGVTQDYVKAAESFEKSAGQGYAKAKYNLGCLYYNGQGVTKDVRKAVKWWEKAAAQGIVEAQHRIDSELNQSSFIFGCLSYLRMNAELIVCAVKDDTDGIDADRKKSQSESHGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWZ9</accession>
    <name>A0A9P6SWZ9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_002854</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001726">
        <property type="protein sequence ID" value="KAG0008979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWZ9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090575">
        <property type="term" value="C:RNA polymerase II transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11405">
        <property type="entry name" value="bHLHzip_MLXIP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10328:SF15">
        <property type="entry name" value="BHLH TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10328">
        <property type="entry name" value="PROTEIN MAX MYC-ASSOCIATED FACTOR X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BHLH" evidence="4">
        <location>
            <begin position="767"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="119"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="288"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="464"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="575"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="669"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="853"/>
            <end position="1024"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="288"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="342"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="373"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="404"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="486"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="498"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="511"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="544"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="600"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="653"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="874"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="920"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="959"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="972"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="996"/>
            <end position="1014"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0008979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1024" mass="110633" checksum="598451FCC05E159F" modified="2023-09-13" version="1">MSFHYDNSFALDQAGLEISLNDFTFDSTQQQLQQHQQQHQQHNQHQELQDLLLQDDHSNNAQSKGTTENMSSTETYDFHSSALSSDMMVTASASTTPIFPTNPDKINLVNTSLQQQLHHQQVMLQQQPQQQQHFHTPHHQVQQQHQLQQQQQQQQSQSIPTSQHDQLLTPTDFTQYMSPLVVQPDTSSDAAMMITDQFDDDEVFFTPLISPAMTPSHSYSNLTHALSTANEIFSPLTSPALQPLRSSIDYLSFPGQNFSPLPTQFHQSQVQQQQLQLQLHQLQPQPQPELIQTNQPPQHQPQQQQQIQISQGSTSNQARIDARSPALNSQRPSVKRRATAERASNGSSSTTPRSGPIRGSLPMSSPAMRPLSNPMSPATLRKQQTSQRRPSSITPASPLIMHFPSSRPSPSPLLISTSQPPLSQAAQASPSPRLVTNMHQLSMIPSSPMGFVNTNNGSQSPALFALPASSMMPPPSSPMILPSASQLNNTPRQRSLMQPQQPIQVQSQHQLSIHQPISTNQPSPAIQPKSDNSPSLESKPDNGDTANTTHAGNSSVLASETPKSAIAPVTPASLMNLGAGSGTESTPASSPKFGAHSKPKPTSQSPSQAPSTGDAAAKMAPAVLPSPAGSSSSSSSSQKRGTKRQANGDISIGSGTMAPSTPRQLALTPSATATSPMPPPPSGFALISPALKPTLMPQHRGSQSMLVSPRLQPQLVSPSLKPWLPGVSTTEAMARLASKSNYQNILDGDHTALGLSYNTDLHSGIELRRTSHKAAEQKRRDSLKHCFDDLRQMIPNIQEKSPSKVFLLKKSFDYICNLKSEVAKRDLEMARLKAQHEFMKTAMESWMATLPEDSPFKKNNDGASLIDSWTMPEEEVKKSTTKEEEAAKRAAEMTELSAAAVEAARTQPGGQNKGGKESQADVEDSDDEGSAMPKAKKPTSRPNPSSSTKGGNSGKKASKNGGPSGAAATSVDDATTQPTTSNSPDKTKLSSKSSDGGDEEEEDDEEDDLEDQEMVDATANNTSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SX92</accession>
    <name>A0A9P6SX92_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DNA-directed RNA polymerase II subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">RPB7</name>
        <name evidence="8" type="ORF">BGZ80_002223</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001542">
        <property type="protein sequence ID" value="KAG0009615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SX92"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003727">
        <property type="term" value="F:single-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031369">
        <property type="term" value="F:translation initiation factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060213">
        <property type="term" value="P:positive regulation of nuclear-transcribed mRNA poly(A) tail shortening"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045948">
        <property type="term" value="P:positive regulation of translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04329">
        <property type="entry name" value="RNAP_II_Rpb7_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04462">
        <property type="entry name" value="S1_RNAPII_Rpb7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000043">
        <property type="entry name" value="DNA-directed RNA polymerase II subunit RPB7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.120:FF:000001">
        <property type="entry name" value="DNA-directed RNA polymerase II subunit RPB7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.120">
        <property type="entry name" value="RNA polymerase Rpb7-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036898">
        <property type="entry name" value="RNA_pol_Rpb7-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045113">
        <property type="entry name" value="Rpb7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005576">
        <property type="entry name" value="Rpb7-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12709:SF4">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12709">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II, III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03876">
        <property type="entry name" value="SHS2_Rpb7-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88798">
        <property type="entry name" value="N-terminal, heterodimerisation domain of RBP7 (RpoE)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="RNA polymerase Rpb7-like N-terminal" evidence="7">
        <location>
            <begin position="2"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="6">
        <location>
            <begin position="57"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0009615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="147" mass="16064" checksum="422B12E1C65E3F41" modified="2023-09-13" version="1">MKEFLLRNLHGDVEGTCSGKVGFIICVLTVTNISPGKVLPGSGLAEFVVQYQAIVFKPYKGEVVDAIVTSVNQIGFFADVGPLQVFVAQKLMPNDFKFDSNGPCYRGDDQMIEKNGQVRLKIVGLKHQATQINAVGTIKEDYLGQIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SX99</accession>
    <name>A0A9P6SX99_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_002515</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001621">
        <property type="protein sequence ID" value="KAG0009320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SX99"/>
    <dbReference type="OrthoDB" id="2442837at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="164"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="211"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="272"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0009320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="283" mass="30395" checksum="4ACCD610EC6B9650" modified="2023-09-13" version="1">MSGSLSLEKRAAQYLDTSEEQIEVTFEANDSYYIENFPLNECVNTFSLPLSPPANYRNYNGMMFPEPTMVVNFYTDDECKEYEFSVQSGVSQFSGAFASAKYVGEFSGVKPGVYDDHEVSNTAPPDANALVDTTTTTAAGTNAPTSSNAATVPSSSVPSGTSSAGFFAGVGLIGLIVIAGIVALGVMGYRKYDRKTRRGGDGRAFMTLASGQDDYDDETGLTGENGPHSSALMQSRAGASFDDERYPAEYHDEEQASDDERVEMNAYPQNPAGPTQTQNPHSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXG7</accession>
    <name>A0A9P6SXG7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_002685</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001671">
        <property type="protein sequence ID" value="KAG0009161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXG7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0009161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="93" mass="10229" checksum="1913BDC2FD8CC756" modified="2023-09-13" version="1" fragment="single">MLHRVSPENKERDLGFLVRTCHAIGTQDVSVTSSLRLDANELYSVESLTKSFSFAKIRDSKVIEISLDEKSVTAAAAIDVIKGYSVDLKRGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXS0</accession>
    <name>A0A9P6SXS0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001457</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001331">
        <property type="protein sequence ID" value="KAG0010475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056251">
        <property type="entry name" value="Arm_rpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46844">
        <property type="entry name" value="SLR5058 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46844:SF1">
        <property type="entry name" value="SLR5058 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23948">
        <property type="entry name" value="ARM_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05729">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50837">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NACHT" evidence="1">
        <location>
            <begin position="368"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0010475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1543" mass="173539" checksum="375E4F128EC1D6D1" modified="2023-09-13" version="1">MVCFQAVYAKQALDFISNRQSSRTTIFRRGKLAFAITDGSADSSLNIREFDRGYEKFTEIFDFSVRSAWYQGLIYIDCMMERQDWLRLEKFILECRFDPNDLFLQGVCLRLEQIAATQPDEDIRNGAIKFLHALGTQSSHSIQQVAQYVLRRLEIKSRTGLPMYSGVSNVPKETTDCDLLRAKENDFLQVWDPLWYVSDKDPLLEAMQFKNIDHWVLKNLNPIFREPSREFQSYSPEMRKYVTDGSELTGTQIEQILQSNLEKATNLSIPSEQDEVGAALKKYYEPYLNIQRVSGKKLSLDSCYVNLVIVAAPDQRRKDKEELQELKEKLGRTCSFKELNRNDFQASIPLEELFDKHRLRDGRNDVPKRILVQGRAGVGKTTLCKKIVHDFQNGLWRDLFDSVVWLPLRQLRALNARNPGDLFREKYFNLTLESEKSSLASALSGRVRDGNVLFILDGLDEIVTDAQSSDNISLREFLKHLLDQKNVIITSRPSGIDTSMLKNLDLELETSGFNPNNIRDYLSIALDPDAVKVVQDFIESTCNSWDLLPLDGDSVTMTGLYQIMVDKLWRKDGERLGKKPDGVELTPPEIRRLSTNQVNRLMANEIEFLGYLAFRGLQDNQIEFKESFLLDVMEELDIHRNDNDKDFLPVHLPEMLKQTSFLHTADADVDSGDDDFNRAWYFLHLTFQEYFAATWLSRHLQANQRSSKALSMLMMTTEESEAFIQQNKYNPRYEIVWWMMAGQLEGVTLGRFFDLLQGAPRDLIGGYHQQLLAGCLKEARSRLDKEVVMTLETELMQWLDFEMALYGERECKGMLGKQSVFPEELLARCLNETKEVQMYALKAMKGRAHWTSSSVDGLIASLQDEDNDISALASEALSTQSNLPESAVKALVMAVHGERSYASYAAAKALGNQSLLTDFNISGLMSGFKFHEVESKYYLAQAISSQLKMRGPVLQGHDSEAQQAAAEVLGAQSSLPVRAILGLGTVSNNAEDLDVKISAARALRAHTKSSKLIYVRFREEKIPDLVDALKAENYRERITAAVALGINPELPEFAVTALIGVLNNTSAGVIKSAIRSLCAQSELNESAIQKLVDKSKGFNIHAQRAAAEVLCAQSPLPAFAVDTLIKALDEHLGATNIVAQVLGAQPTLNRCAILAIIRALHIKGWSAKGTNRIFEDENGNLRAFVSSVPRCKLSKPEVLSSISALQDKDKSIRRSGAEKLGTQCKLPEYAIQALIRALDDTDLDVMNSVAQALDAQASLTDSAVLSLLSTFHGKGWITARSAVMRLGLRAMLPERVVIAVINNLGDDLYGRRSEEPLPNSESPMLDAPDMALTVTPKEENREADHSASPILGAGTGSPDLSLVLVEALQDKDRRSRRLVAEKLDALDVQPTLSRSDIDDFIRNLETKKACDRISTKTTLSESPMQALYRSLPGKVQRIRPYEVCGGIDDYPVIVLDKHLHSVFKALPELSVFEIVVLYRCYFFRHGCEHSASLFFKGNRLCFYTERGYGETEPISLKNMVKIISAFRVVQKEVGIPPIRLVNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYC2</accession>
    <name>A0A9P6SYC2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Hydrolase rbbp9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">RBBP9</name>
        <name evidence="1" type="ORF">BGZ80_001405</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001318">
        <property type="protein sequence ID" value="KAG0010524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYC2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010662">
        <property type="entry name" value="RBBP9/YdeN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15394">
        <property type="entry name" value="SERINE HYDROLASE RBBP9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15394:SF3">
        <property type="entry name" value="SERINE HYDROLASE RBBP9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06821">
        <property type="entry name" value="Ser_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0010524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="174" mass="19467" checksum="008E54F4622D2A24" modified="2023-09-13" version="1">MSRIILIPGNGNDCVEVSMWYPSVIEALTEAKDLRTGQHLFPGGGVLRTFPDPYDAHEEVWIKFMEEDIEIGENDVVIGHSSGAAAIMRYIETRKVKGVVLVSAYHSDLGDASELTRSNANASPSDHLVPIEEQREVASKIVGVEYRELPNRGHFIRDHQFPELVDNVVQRMIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYN4</accession>
    <name>A0A9P6SYN4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">protein-histidine N-methyltransferase</fullName>
            <ecNumber evidence="3">2.1.1.85</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_000128</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the methyltransferase superfamily. METTL18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.85" evidence="3"/>
    <dbReference type="EMBL" id="JAAAID010001020">
        <property type="protein sequence ID" value="KAG0012206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYN4"/>
    <dbReference type="OrthoDB" id="1723750at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018064">
        <property type="term" value="F:protein-L-histidine N-tele-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF39">
        <property type="entry name" value="HISTIDINE PROTEIN METHYLTRANSFERASE 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="237"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="243"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="261"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0012206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="418" mass="46671" checksum="FD247EB62115E9E6" modified="2023-09-13" version="1">MFKFNFTAEDLEIDDPELVTQQDEDQIEELSKPLESLSVSSSSSTVVPASRLDIQSKSCLQSLPLTLHYELAQIPVLKQGTGAATAISIDMKTGEKKEIVTIYKRNLEDVKFQIAQDDDDFDTEDNNKTKEQEVAKQTISGPGGAEMLALAGKSDLVKGVYEGGLKTWECALDLVAYLAEQNENYDGKKVLELGCGSALPGIYILTQSNSAKVDLQDYNDQVLRLVTLPNVLLNTYVRPDQQPAEEEEVEEEIKEQKEKTEGEDDEDDEDDEDDEEHPEADPEDGDFRGVELDLPDSFEDKLALAKKVEAQSSFYMGDWSGLVDVMAFSGDEDKYDLILTSETIYAEESHQKLYDTIKNSLKRGGKALVAAKTFYFGVGGDILSFRRLIEKDNVFNVKVVFSAQAFVRREILELTFKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYT4</accession>
    <name>A0A9P6SYT4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Iron-sulfur assembly protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ISA1</name>
        <name evidence="5" type="ORF">BGZ80_000106</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Involved in the assembly of mitochondrial and cytoplasmic iron-sulfur proteins. Probably involved in the binding of an intermediate of Fe/S cluster assembly.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the HesB/IscA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001016">
        <property type="protein sequence ID" value="KAG0012235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYT4"/>
    <dbReference type="OrthoDB" id="333486at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.300.12:FF:000001">
        <property type="entry name" value="Iron-binding protein IscA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.300.12">
        <property type="entry name" value="HesB-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016092">
        <property type="entry name" value="ATAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000361">
        <property type="entry name" value="ATAP_core_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050322">
        <property type="entry name" value="Fe-S_cluster_asmbl/transfer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017870">
        <property type="entry name" value="FeS_cluster_insertion_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035903">
        <property type="entry name" value="HesB-like_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00049">
        <property type="entry name" value="iron-sulfur cluster assembly accessory protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10072:SF41">
        <property type="entry name" value="IRON-SULFUR CLUSTER ASSEMBLY 1 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10072">
        <property type="entry name" value="IRON-SULFUR CLUSTER ASSEMBLY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01521">
        <property type="entry name" value="Fe-S_biosyn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89360">
        <property type="entry name" value="HesB-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01152">
        <property type="entry name" value="HESB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core" evidence="4">
        <location>
            <begin position="24"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00054873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00071673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0012235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="127" mass="13810" checksum="E8A5AC481DA1D5CE" modified="2023-09-13" version="1">MSLAAKVVKAAAAPRIVRPRKAVLTLTPAAVTRLRALTDGPEPKVVRVGIRTKGCSGQQYDLSYTTKKEKFDEEIKQDGVTVLVDNKALLSVLGSEMDYVEDKLSAQFVFNNPNVKESCGCGMSFMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZI1</accession>
    <name>A0A9P6SZI1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Arf-GAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_010758</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000785">
        <property type="protein sequence ID" value="KAG0013936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZI1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.150">
        <property type="entry name" value="Arf GTPase activating protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051718">
        <property type="entry name" value="ARF_GTPase-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037278">
        <property type="entry name" value="ARFGAP/RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001164">
        <property type="entry name" value="ArfGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038508">
        <property type="entry name" value="ArfGAP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45705">
        <property type="entry name" value="FI20236P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45705:SF1">
        <property type="entry name" value="FI20236P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01412">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00105">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57863">
        <property type="entry name" value="ArfGap/RecO-like zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50115">
        <property type="entry name" value="ARFGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Arf-GAP" evidence="3">
        <location>
            <begin position="18"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="169"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="374"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="258"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="292"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="317"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="345"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="374"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="392"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="424"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="461"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0013936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="481" mass="52042" checksum="08E133E2AD230F3B" modified="2023-09-13" version="1">MATRSARTADKTTNDKHSRILKALLQKPENKYCVDCRKKVSISDVSCVSDAPVCTAPWAHTSAKPIIPAFVMVMYFVLFAVKSVDLDSWTPDQVENMIKWGNVKANKYWEARLPESSIPNENTSGIDPWIRSKYEWKQFAGKDPMPDPSELGPIDEALIADLRGKVGHSRAHANRSSGSFESFGIIAPPPSGNTTVRSSFPKPPTSSSSVQGADLFSIGQPPSSSVSKPAAQPDFFGLNDEPEIVSPVQPRSQRNSLQSPQMQQPQPTQPAQPAQNSASQDLFSLITPAPSGGQSQNGQAAATTPVSPVQAKAGNTDWKNSIMSLYGNQPSGSNRNSTGLNIGMQQQQQQQQQQQFQQQQQFQQQQQFGQFQNAGSFGFGQQQPQQQQQPQNLWGNSNGFGAMQQASGASTTSPSSFDIFANSGFGSQTSNNNFNHPTSTNPVPQGGDLFSMIAGAAAKSPVTSPTSTQNKNNRLEMHSNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZJ4</accession>
    <name>A0A9P6SZJ4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_010888</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000808">
        <property type="protein sequence ID" value="KAG0013736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZJ4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0013736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="579" mass="66222" checksum="6E9887455BC91716" modified="2023-09-13" version="1">MNLSIFDIPHLRDEVTRYLSKREQADCIVVCKSWYGYFTPALWRYPLENHKFHHRDIENLVRHKDHIQTIRDSGLRGKRAKSSILRYAFPILRLLEITISSTTQLHYERSVLRFIATTPTLRVLNLRLAGYGDRFHEKFVGILGSHPNLLNLRFGSYEQMRSVQVQEIVQACSKFTSLELNFTLERGRVFLDDVVELEDALAAKGQFTQMKDTNIRDLAIFPSGTGKHQLIIAPLIERCPLLEKLTLEGLTDETILDITAVLKSGRCYLLKEVVSSRMLSGCNRKYMEDLLCSIGFATNITTSSGRNGGGGLEAYTQRISGLWSAALIPRYSQTLARLVLAGNALYGLKSMIAIVYGLPRLQMLTIRISLSSVPEKDLDWTGLLQNRWACADDMIDLALKIDVPHTFKSVLDPMWKGSVVDQTFEWLFSRIGQLRMLRYLKLDCERDLLSLRNEPKYLGKMTELKQLRELLFYSESPGLVSAEEAEWMIENWPRLINVVISENLFGRDKALNRSLSIINLPSQSGFKRSPRPVRNSPASKPRARFLNPEQLVTLRSHEMDLERVLAANNQLVRMNDTKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T065</accession>
    <name>A0A9P6T065_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_009854</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000629">
        <property type="protein sequence ID" value="KAG0015435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T065"/>
    <dbReference type="OrthoDB" id="2428322at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0015435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="589" mass="66754" checksum="A424F30851102F20" modified="2023-09-13" version="1">MEGDRPQRTAKEKASISIKDSLPPPEHSDLTSSDSDGDTYKPQINEPSSGKGKERRRESLSDGKPQINEPSSGKGKERRRGSPPDSEDGADPNNDQAHSRTIEEKTEIKSPTKQTNREKNDGALKDRKKSETSQKRKRASHRYDDYHDSGDDDDDSDDSNISASDDDIAPTVKRKNTGPPAKIKTTQYFKGNYWPNFTQAPLMSLVHSLMTQEQKAARALAFMVLDGGVDDETYRWPVRENLLPAVPKSSFMDESADADFFEQQGMGFVEELTGVPKTEADYSDEESGDESDEEVGSDEGVNSANEADEERELHERRLAKKRRKLRQERHANERMANSRLEQVNSFLREEIVAFARKQYRKGISHRVKDLHSLQKETLPPFRIQAARSSIGGSKRGDEEEDELTPIQENTAAFAAEDSLRRILDRLPYVIRQGALGEAPDYVKLGLPKPVSSVAEYERGWDTLMAAASISGVDDRILKKVGLRMKNLLSQSKHSRYYEAPPKAMFATAESNENMENLELPKIKVPCVFKQPPPPKELWKTSPAPLYLSREFIDPLDPKYNVESTMKNIRERRRWLVEPSPYRPKKKHRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T066</accession>
    <name>A0A9P6T066_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_010022</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000655">
        <property type="protein sequence ID" value="KAG0015147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T066"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16563">
        <property type="entry name" value="RING-HC_RNF220"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052443">
        <property type="entry name" value="E3_ubiq-ligase_RNF220-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031824">
        <property type="entry name" value="RNF220_mid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040178">
        <property type="entry name" value="RNF220_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13459">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RNF220 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13459:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RNF220 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15926">
        <property type="entry name" value="RNF220"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13923">
        <property type="entry name" value="zf-C3HC4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="3">
        <location>
            <begin position="180"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="86"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0015147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="232" mass="25949" checksum="14A731318BD556DA" modified="2023-09-13" version="1">MSEAFEEYTWAGQTRVRATALFEGGMGSLGSVSRSGQEDIDDDLNVEDDEEDEYGGAQFTERDVVMNDLDNDGDELREIVLESSAAVQRAVSPPVPPEQRDRIDRDVDIEDESVDPGGVDDEVDEDEEIDLEGVDGEDEESRMDTMLSSAFASGDTRLVIEALRSKIKHLESVNKNVPSCLICLEPYTIPLTSIVCWHVHCENCWMKTLGSKKLCPQCQKITLPKDLRRIYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0G5</accession>
    <name>A0A9P6T0G5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DNA-directed RNA polymerase III subunit RPC8</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">DNA-directed RNA polymerase III subunit rpc8</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">RNA polymerase III subunit C25</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">RPC25</name>
        <name evidence="12" type="ORF">BGZ80_010268</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000699">
        <property type="protein sequence ID" value="KAG0014705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0G5"/>
    <dbReference type="OrthoDB" id="10256606at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006384">
        <property type="term" value="P:transcription initiation at RNA polymerase III promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04330">
        <property type="entry name" value="RNAP_III_Rpc25_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000221">
        <property type="entry name" value="DNA-directed RNA polymerase III subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.120:FF:000002">
        <property type="entry name" value="DNA-directed RNA polymerase III subunit RPC8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.120">
        <property type="entry name" value="RNA polymerase Rpb7-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013238">
        <property type="entry name" value="RNA_pol_III_Rbc25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036898">
        <property type="entry name" value="RNA_pol_Rpb7-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004519">
        <property type="entry name" value="RNAP_E/RPC8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045113">
        <property type="entry name" value="Rpb7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005576">
        <property type="entry name" value="Rpb7-like_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00448">
        <property type="entry name" value="rpoE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12709">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II, III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12709:SF1">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08292">
        <property type="entry name" value="RNA_pol_Rbc25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03876">
        <property type="entry name" value="SHS2_Rpb7-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88798">
        <property type="entry name" value="N-terminal, heterodimerisation domain of RBP7 (RpoE)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 12" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="RNA polymerase Rpb7-like N-terminal" evidence="10">
        <location>
            <begin position="8"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase III subunit Rpc25" evidence="11">
        <location>
            <begin position="83"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="157"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00072526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00073027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00077605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0014705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="212" mass="24233" checksum="14836CE261D85802" modified="2023-09-13" version="1">MFNLAEIKDTIKIEPSGFRKKKSQAITDEINRKYANKVLQDVGLCIAMHDILYASEGFIHHGDGCSYVTVHFRMVIFRPFIGEILTGKIRSCNHEGVRVTLGFFDDIFIPSGYLQAGSQFNSEEQVWVWWWEENEMFMDLDEPIRFRVESENFFDTSPSVRPRKEGMDTPDLTANSSRQAPYSLTCSIDGDGLGLLSWWEVEVEGDAEEAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0M7</accession>
    <name>A0A9P6T0M7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_009264</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000539">
        <property type="protein sequence ID" value="KAG0016370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0M7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043539">
        <property type="term" value="F:protein serine/threonine kinase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000068">
        <property type="entry name" value="STE20/SPS1-related proline-alanine-rich protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047173">
        <property type="entry name" value="STRAD_A/B-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48014">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE FRAY2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48014:SF21">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE FRAY2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="1"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="193"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="299"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="460"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="593"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="243"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="303"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="460"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0016370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="628" mass="67335" checksum="7614006FF59795D9" modified="2023-09-13" version="1">MKTAYPDGFDEVSIATILKQALQGLDYLHKNGHIHRDVKAGNLLMDDDGSVLLADFGVSSSLMEGGDRRGTRKTFVGTPCWMAPEVMEQAGYDYKADIWSFGITAIELATGHAPFAKYPPIKVLMLTLSNDPPTLDRESTKHRYSKLLKEMIDSCLQKDPARRPSAEKLLNHSFFKQAKKPSHLVTTILRNLPPLEQRPQKKATQKTPLPQKGVSWDFDADDTNEPPVRKPRTVTFEPTNRPISTATTDSIASSGTVGTPIIESRSLDTFPDDGVSSQIATQAGDKPIKKSRFVVEDPVIPAGSSSPTSNYGTDVGQTSSDAISPYNAASSNSVQSGQSLHGLGVSSNGAAEQSTALEVKKGRFSVKDTLSIASPTPGSVKATTGNEALLSPTRSLTNSPIDGAADGVQIGAPVELGPSERKSRFEVHHNHAAPAPAGSTSTNGGVLNSPGLTNINVLSRDSSQSRISRFSVEPTQSPLEPAPNSATAPSTGTPNQSKRSRFQVSSVEGKPGEISTETLYRQNEQQRAILIELFTGLGLKPSSSTISPSTAAKNQPENVQPQSVVNTNTVATVVAAATTANTSGGSIHRQENQSNLERQLQMTARENESLRRENEALKRELDRLRRGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0S3</accession>
    <name>A0A9P6T0S3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_009898</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000635">
        <property type="protein sequence ID" value="KAG0015368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0S3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045111">
        <property type="term" value="C:intermediate filament cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005815">
        <property type="term" value="C:microtubule organizing center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026081">
        <property type="entry name" value="DISC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14332">
        <property type="entry name" value="DISRUPTED IN SCHIZOPHRENIA 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14332:SF3">
        <property type="entry name" value="DISRUPTED IN SCHIZOPHRENIA 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="135"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="175"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="317"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="385"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="927"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="558"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="784"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="48"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="61"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="78"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="91"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="149"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="210"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="280"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="331"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="405"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="421"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="439"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0015368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1052" mass="118053" checksum="331CE9B03AA9D9C2" modified="2023-09-13" version="1">MAKFSNSFNSLFHSSGASPPARDQSQDLDDHDDDGSKEHTGLLSRSRLSKDGSQDDILRSNIDTGRQAGNRNMVHSLYASSREPTPQRRQTSVPGTPTTGHHGSGASSLFINNMSRLWDNDDDDNLDRKSRLTSSMIIEDASPPLPWKEPSHSFESREDLSISKRFSMDAISDGAFAMPSSLPEPHQLSQPAEAPPSIDSNTSVNAHSEPKKRRWGPKGQHKSTPESALAEDASKQQQQQESLVADTERPFSPTEAAMQEPITSSFFSDPEESVADSKQSKSSQSKHSSFGIAALSGSGKGIVSGLSSLRNSIMIPALSSSTTNKAERPISLQTKFSAESSSLEFSTDGQPQWQNESTPPPLVSSPSLLRSGFLKFGNEVTTPGRDFGSASLFSERRHTRSVKDSSNSNSRSASPKLHRTASSPASERRPASVQSSHRPSSRTSRHRFTNQNSAAHSLSLLEYEFQQLVQKQSQLSIHKVELCKELISLYSRRNINEKKQEEAAKMEQFEEADSAATTIRLVQERIQKLEKIYMDTDQALWKCKKRQDELGMSISEMHQAVIEELDQMRRVREQEQEEYQAEMQRMREKEIERIQGEREEVDKEKGDIALGQDFLEKNEAELLERMEEETKAEQEELDDLKEKQNATRAEIQELTRKLEQLNNQDKEYSRGIEVLVQKISMIAQQFDGKAKEVAREKRELERRTADIQHRVLKLERQESNLQKAAQEANAVQDGVRNEIQQITSQQDRLGEVRRLFEEELITIQKLRLEEEAFREKEAGWNMRSGSLSENLKEHEAKIESLTNASAADQKAITNLELDLEATQKRISTIESLKALSVQRRDFRQASHCSSEIAKCKDTIAQQQSELERLTAKMSGDTHEQLEALQKEYESARAFVIGEEASLFKEIQESTTEILARLSTFSISLASNEDKGAKESAEDDVSAESRNAPNTAMGQLSRLLLSELRSEIEGVQEMSRIQYGREEAVPSVNSHLSDTHQSVEVKELTTTNGSKDGLSAGMDIEEQKHTLERDIQAAVAEEDYETAAKLQERLDAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0X9</accession>
    <name>A0A9P6T0X9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">ER membrane protein complex subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_009679</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the EMC4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000600">
        <property type="protein sequence ID" value="KAG0015735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0X9"/>
    <dbReference type="OrthoDB" id="369569at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009445">
        <property type="entry name" value="TMEM85/Emc4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19315">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06417">
        <property type="entry name" value="EMC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017207">
        <property type="entry name" value="UCP017207_TM-p85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="76"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="19"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR017207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0015735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="178" mass="19680" checksum="5591153D8BA0ED70" modified="2023-09-13" version="1">MSTTATQTWKFDFTSADASHSRSNVADPPGYVGSKDIASRGNRGAKNNEMDNELLKVKKAWDVALAPGKQLPMQAFMLWMSGNSVQIFSVAITAMLMFSPIRALMSMSQVFERYETVSPVKVSFLESKLALPKLTFVALQILTILLGMWKLNSMGLLPTSHSDWLAFLDPKVPLEYAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T114</accession>
    <name>A0A9P6T114_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRM61</fullName>
            <ecNumber evidence="1">2.1.1.220</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">tRNA(m1A58)-methyltransferase subunit TRM61</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_008559</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.220" evidence="1"/>
    <dbReference type="EMBL" id="JAAAID010000468">
        <property type="protein sequence ID" value="KAG0017159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T114"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031515">
        <property type="term" value="C:tRNA (m1A) methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160107">
        <property type="term" value="F:tRNA (adenine(58)-N1)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049470">
        <property type="entry name" value="TRM61_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014816">
        <property type="entry name" value="tRNA_MeTrfase_Gcd14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12133">
        <property type="entry name" value="TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12133:SF1">
        <property type="entry name" value="TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08704">
        <property type="entry name" value="GCD14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51620">
        <property type="entry name" value="SAM_TRM61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRM61 C-terminal" evidence="8">
        <location>
            <begin position="129"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00033309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0017159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="430" mass="48408" checksum="632EE513D054E603" modified="2023-09-13" version="1">MATLPRLCRLPNTPPLSYLQHCRTNISLTHRSLRSISTSTAVPEPEPENEAERYISPQVDPKFRYGDVIVINDGKGDRRIIGPLKEGIFRDSNTGRLKHDDIVGMSPLSTIKTHKGAKFTLHWPTLDEYCTKVKRQASIMYPKDATSAVHLLDLFPGAHVLEAGTGNGSMTLYIQRAIQGPGSHLDTVDIRNEHSQQAEENVGRFWRGMYRPGIIFWRSVGGLQKVIKHLRGLETATDNTSESESGAEFDRDGRPLTKLEIKRKKLTEAKEVLPPNPHPVGHQYDAISLDLPDCKSVLLDLMPLLKPDRPMCLYMVNMSQVLELVQWMRKHDDKHSYIVERVLDVDWQEWSVRSAAVRSKVKGRVHVGGFGHVSLLRQAQPSDGETENQESNFTTAADNIPDDAVGWICRPLHMPTGHTGFLVQLRKNSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1R9</accession>
    <name>A0A9P6T1R9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Dead deah box rna helicase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BGZ80_007072</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the helicase family. SKI2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000356">
        <property type="protein sequence ID" value="KAG0018517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1R9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055087">
        <property type="term" value="C:Ski complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070478">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18795">
        <property type="entry name" value="SF2_C_Ski2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000354">
        <property type="entry name" value="ATP-dependent RNA helicase SKI2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000987">
        <property type="entry name" value="DEAD/DEAH box RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3380.30:FF:000001">
        <property type="entry name" value="Ski2 ATP-dependent RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3380.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1500.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025696">
        <property type="entry name" value="Beta-barrel_MTR4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048392">
        <property type="entry name" value="MTR4-like_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050699">
        <property type="entry name" value="RNA-DNA_Helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016438">
        <property type="entry name" value="SKI2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012961">
        <property type="entry name" value="Ski2/MTR4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040801">
        <property type="entry name" value="Ski2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131">
        <property type="entry name" value="ATP-DEPENDENT RNA AND DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131:SF1">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE SUPV3L1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08148">
        <property type="entry name" value="DSHCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21408">
        <property type="entry name" value="MTR4-like_stalk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13234">
        <property type="entry name" value="MTR4_beta-barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17911">
        <property type="entry name" value="Ski2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005198">
        <property type="entry name" value="Antiviral_helicase_SKI2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01142">
        <property type="entry name" value="DSHCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="338"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="583"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="546"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="551"/>
            <end position="573"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0018517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1260" mass="140760" checksum="9A28B33DA0D8B07C" modified="2023-09-13" version="1">MHNLTTILAQAALTLPRSIAGPQTYEQIKQDIEQEHLFPSNTFSTEWLNKCQEIFDRDQEFTTLLSMDPSPAESTIALEPHNVYGVRGGYYEKNLQTAHLVGTNAVASTSIMTAKNSTSFSRAPGKRTDFVRGKAGYFPFTPGGLDIEEIKGASALEAEKNALGMDDVDIARTIVEGLSLESEGLLTKPPGFDRGLFSDREADAQVEEYESKTGAKFNIADILTGQDIDEEADFEALLDPVSRSSVEDTKTTTTTTEATTVVVNPEPETETPDEVDAILDSVIPVSVPKRTITAAQTKGREWAHVVDVNEAFDDFYTLVPEMAHPFPFELDTFQKRAVYHLEKGECVFVAAHTSAGKTVVAEYAIALAAKHMTKAIYTSPIKALSNQKFRDFKDTFEEVGILTGDVQINPEASCLIMTTEILRSMLYRGADLIRDVEFVIFDEVHYVNDLERGVVWEEVIIMLPAHVTLILLSATVPNTKEFADWVGRTKKKDIYVISTPKRPVPLEHHLFANREIYKIVDAKQTWLNMGYKNAVDALTKKEADAKVAQRGGRGGSAGRGGGRGAFGGGGGGGWRNDKQDKNLFTHLVGYLNKKQFLPVVVFTFSKKKCEENASGLSSTDLMTSSQKSEVHVFFEKALVRLHGTDRDLPQIQRMRDLLSRGIAVHHSGLLPIIKEIVEILFARGLVKVLFATETFAMGVNMPARTVVFSGIRKHDGRSFRNLLPGEYTQMSGRAGRRGLDSTGLVIIACNGDPPEATELQEMLLGKATKLLSQFRLTYNMILNLLRVEALRVEEMIKRSFSENSNQKAMPEKEKLFAESAKSMEGLKKLDCFICNKDIEEFYNMSHRMVTINHQLMDRIVRQTFGIKALSPGRVVVLNSKFHRNALAVVLKTVAEADMAAKQSKSYWCCILTEANPEKSNIDVLVPVTRLKTSSQQDTSQSIEAVPYQDIFTITDTIIAIDAEAIIRKDTAALTKARKDLNRYAEEVEERQGGLATEFNWSKIKDLEFRQHLAQKQTLFAKILECQCNKCPDLKAHYAMIYQERELQYKLEELQRTISDQNLELLPDYHQRVAILKDLNYLDPENSTVQLKGRVACEINTADELILTELILNNMLSEFEPEEIVALLSCFVCQEKNASEPMLTPQLEKGKDMILAIELEMAEKQKAHGLESATAPGTSALRFGLTEVVYEWARGMTFKQITDLTDVQEGSIVRTIHRLDETCSEVRNAARMIGDAALYNKMELAGQAIKRDIVFAASLYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1Y2</accession>
    <name>A0A9P6T1Y2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Golgi reassembly-stacking protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">GORASP2_2</name>
        <name evidence="7" type="ORF">BGZ80_006563</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000325">
        <property type="protein sequence ID" value="KAG0018911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1Y2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.42.10:FF:000026">
        <property type="entry name" value="Golgi reassembly stacking protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007583">
        <property type="entry name" value="GRASP55_65"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024958">
        <property type="entry name" value="GRASP_PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12893">
        <property type="entry name" value="GOLGI REASSEMBLY STACKING PROTEIN GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12893:SF0">
        <property type="entry name" value="GRASP65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04495">
        <property type="entry name" value="GRASP55_65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51865">
        <property type="entry name" value="PDZ_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PDZ GRASP-type" evidence="6">
        <location>
            <begin position="14"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="193"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="276"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="164"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="197"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="220"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="295"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="314"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="347"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="418"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="429"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0018911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="494" mass="54033" checksum="0C65248CD6CE8382" modified="2023-09-13" version="1">MGNTTSGDSGRYRYGYHVLRVKDHSPSSQAGLRPFFDYIVAVNDIRLDITPESPAEEAGLRAHSDYIIGTPLGVTRGEGDLYELIEEHIGEPLPLHVYNADTDQVREVVIVPNEDWGGEGLLGCDVGYGYLHRLPNGPIRHQDEKRAQNEITEIRVEEGPALSEEQTTTNFPPIQTQGGFVSLATTENAQHRGTGIGTQTFTPSDHIQTDKPTHIVQPNAEENSISTMEQEPTKSDSPNSDNILQSNANGTPELTLQKSEPTQAALGHCDMDVSSTDVHSSLQAHSHHSRPETSKVASHASSSTAITDKPADGSLSQKIKSATSEPSAETTASVDSTTTQDTPISPPIVSSDSVVQEQVDTTKQEQEQEPSLPNSETRRQPPLAIAARMNPGIHGRGARKGHDGFSERGGVSLRDVQAQAQQQSAEYRTQMERYESEYGPKDSQKQESQRDEDSQEDKDRGDRQEPQNAEPEVHEYVVEGMIRNMSLGSSIFPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2B0</accession>
    <name>A0A9P6T2B0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">PNPLA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_004869</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000244">
        <property type="protein sequence ID" value="KAG0020037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2B0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006641">
        <property type="term" value="P:triglyceride metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07229">
        <property type="entry name" value="Pat_TGL3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050301">
        <property type="entry name" value="NTE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021771">
        <property type="entry name" value="Triacylglycerol_lipase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226">
        <property type="entry name" value="NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226:SF44">
        <property type="entry name" value="TRIACYLGLYCEROL LIPASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11815">
        <property type="entry name" value="DUF3336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="3" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="6">
        <location>
            <begin position="137"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="497"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="557"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="4">
        <location>
            <begin position="168"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="505"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="572"/>
            <end position="582"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0020037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="606" mass="67522" checksum="71ADA7AEABF58533" modified="2023-09-13" version="1">MINELAHSKSFDEWLAKATELDILTGSEAWRNNIQSNIYDYNLILTRRHHLKVIRESGDVSAMMYLLRSGLLRNLGGITDPRLFCHSYLGTKHLIESYMDEVVSQLEQVAYTKTELTKQAKIDFFMETRQSFGSSALLLHGGASFGMYHLGVVKTLFEHGLLPRIISGASAGALMAALVCVKTDDELPSVFEEGGIDLSAFQRVGERGNLSRKITRLMTEGYLLDINVLQKCIEDNVGNLTFDEAFKRTKRVLNITVPSSSKSEGPKLLNYITSPNVLISSAACTSASMVGFSSAADLLAKDKSGKIIKWTPTASNYTNPITPSFFSYGAVSPETPLMRLSELFNVNHFIVSQANPYIVPFMSRGLRDRKSGMSDRFTIGLMEKIARVFLAEIKHRMGQLNQIGILPHFIVQLVEEKVSGNVTIVPEVQIQDFLTLISNPTHKSIQYWILKGEQSTWPFLSMLKYRLMIELALDRILLRLREEASASAIQAGIGIDGQQFSTGKSPHHRRQKSGPKRLTPHSTARRESTSGIGGKGGNAHRFMRMTSYIQPGEHVFSDQHGLHQGHNLQPHQHADVTMHCPDDDLGSPDSGRPTPFSDPKRSKSLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2J8</accession>
    <name>A0A9P6T2J8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">IKS1</name>
        <name evidence="12" type="ORF">BGZ80_004557</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. GCN2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JAAAID010000231">
        <property type="protein sequence ID" value="KAG0020240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000306">
        <property type="entry name" value="IKS protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050339">
        <property type="entry name" value="CC_SR_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042:SF138">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE IKS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="369"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="46"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="303"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="494"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="727"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="934"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1080"/>
            <end position="1165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1303"/>
            <end position="1338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="57"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="317"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="337"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="512"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="772"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="807"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1085"/>
            <end position="1098"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="1099"/>
            <end position="1108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1131"/>
            <end position="1142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1145"/>
            <end position="1154"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0020240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1363" mass="150768" checksum="1732FA1A028682A9" modified="2023-09-13" version="1" fragment="single">MNHPQDEHSSEGHEKQRKASNEKSTSTSPSLLHPLQLQHQQQPWLIPHPNLPISWHNNDHNHHSRESSHANSEGTSTMRHVPLIQLNDNMKDNRPAFKDTTSSSTIDGSSLQDYRWSQNSLSPDQRLLQYRESVLDGGHESDPSELLRSPVLFTGSPPNNNYLSPTHDMYPLGRPNRSMSLSMGTNVWNERARTPPALSPPPSGSEVVPYSQEWRVILRSQPQGRTVLYNPQMQSLVVQTTVGLDSHPVSLRDDPRLCRSCRRRLDLDEPVDEEDISNSSSAFMDSNYFRMLADANMALSGRGSLQEGVGSPLQTQSPLGSPTSSSRTSLDLDSRVPLHNSSSSNLRSHPLSPHLSHDALNQGYYERFFMEQKKLGRGYRGSVFLCQHVLDGIHLGEYAIKKVAVGDNHDWLVQMLREVHLLERLHHPNIVSYKHAWLENHQLHKFGPEVTCLFILMECANGGNLEEYVEQPPEVKPAEPDSFVTPGVMELEAETVKPQSARERLQSKRQRLQGTLSSSGGKSGESEQASAQPRHHLSITEIWGFFFDICEGLAHLHQLGIIHRDLKPPNLLLSYTNGQVKGANGERPRILITDFGECEILDQAAKRDRTGATGTLEFLAPELLAVDTEGRYTNEFSFKGDMWSLGMVLYYLCYSRLPYSQIEDVDILRTEIRQFKSITIPEDGPDRIIPEELKILIRVLLSPEKSKRPSCDDILKTLSHQRERMMRGDMDSATTPIRASTDLGYGESEPTAKAKGINGSDDGGATYPSAKRQVTSIKSSSNRQPHRQNYHPVRQNSLKAPVRRQNRTTLISESSSKASTGHGQASFTAMVRNTASPSINLHKKVKPLGLGLRHMLRRKMNHPAVAADGAGIRRYSSCNDDNGGYKPILDLIAPKATYPLALEGSIRTLSSSPTDSISKRSSPTQVDMAIAQHQDFQGRKQAAQGKESTLGSTMELASECEPGSSKSDAMDGSKPPASSKRDLATGDQISNTPDSKKSRHDGQGQSSEAAPLHEALNLEDSFANFSTTNNRRINHVINNSANGGLENSGPHTVEEGTTVAQSRPVLGKTYWTKLASTHAKSNSNIATPATTDATGGAIDADESSEDGDYMPSGTGVGVGLGRRRTRTRSRTSLDKDRPDHSQGIRSTTRQGSRQSSRRNSRQMSIDQKSLQQLQLYRHQLQEQRSHHFLPEDFSFLFMFVSLIIRIWLCLRICNPVMVRPIVLYPVLILTAVWDRYLISLVSEKIKASSSMRSGAKHQRGFGGIVGALGISEGAGATASLSTLGATQEHGSPRKRAFGKITSNRNGIKDAGNEDTGLDADAETDAHSEGGGGRRGRRGSLMMERGEHDLDQHIKHSAPIWQAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3I6</accession>
    <name>A0A9P6T3I6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Replication factor A protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RFA2</name>
        <name evidence="5" type="ORF">BGZ80_001379</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000131">
        <property type="protein sequence ID" value="KAG0021947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3I6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000781">
        <property type="term" value="C:chromosome, telomeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005662">
        <property type="term" value="C:DNA replication factor A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04478">
        <property type="entry name" value="RPA2_DBD_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040260">
        <property type="entry name" value="RFA2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014646">
        <property type="entry name" value="Rfa2/RPA32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13989">
        <property type="entry name" value="REPLICATION PROTEIN A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13989:SF16">
        <property type="entry name" value="REPLICATION PROTEIN A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036949">
        <property type="entry name" value="RPA32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OB" evidence="4">
        <location>
            <begin position="66"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0021947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="264" mass="28696" checksum="A97F27F7486E0B98" modified="2023-09-13" version="1">MSNYKPYSHAGQGQGYVQESFSSDVGATKRIANHTLRPVTIKQLLSVTQTQADNDFRIDGHDLGQVTFIATVRNINQQSTQHTYTVEDGTGTIDAKRFPTEDEDSAELNTIVVGTTVRIVGILKSYNQKFSINIHAIRPIHDMNELTHHLLEVIYVHVSSTRSKGAGGMSMSSAPHNNFASHSMANVGNVGAGSGVVGEDIPEQISEMIRNHSDAERGVPRHEIIARFGQLTGGPEAANELINAMVSEGALYTGEDEDHILVAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T425</accession>
    <name>A0A9P6T425_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_008682</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000048">
        <property type="protein sequence ID" value="KAG0023644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T425"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF120">
        <property type="entry name" value="KRUPPEL-LIKE FACTOR 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="415"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="445"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="28"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="375"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="569"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="38"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0023644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="593" mass="65081" checksum="EABAC4AA1D89E1B6" modified="2023-09-13" version="1">MSWTTDADTPRSIAQSYSLACTISSMSALNGPPPSAQPRLSSNQGASSPPFNAVFKPEVDPWQFEYRDRADGISTNSHQKPIVRSPKFAEAAFSHQGRYIATSQDDMTNPPNPPSTAAERELVTMIPTSSHQLDSYKCLSGLSMAASHIENLAENSTVALSATLQDPLYLGLSRSQPGDELNRQTKDFPKEETNAGTVFQHVPHMPQDIQNFVPQAHSMRSNTSVLTNRASPIATPSTLAPHYNENHTTTQHGHYNNYFPPSSVCSTLTGFGLSPCKNANTPILSSQVLPIFSSDTSMGVLVGPETRYSPPASMPMMLSSPRSSPPLASTLSSAFMLACSVSSAPPSLSPPPRSYMPSTSSCSTSLPLPYADPSLARHNGANVTPVKSNLSSLPPSSGPRRKVNTEALKEQNTVYVCHYPNCGRIFNRPFNLKSHGLTHDDVRPNQCDKCSKSFARVHDLHRHRRGHSPKSFVCIVCQGSFARQDAVTRHLKIAEGMNHCGLLLRRHRIDIRDAAAGRVRRCVLGDESTIRKKLEEIEDLVRRARLRKNMSMRSMSANISTLGMNMNAVQQQQQQHQYHRRPMTSDSAVAKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T439</accession>
    <name>A0A9P6T439_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_009523</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000058">
        <property type="protein sequence ID" value="KAG0023399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T439"/>
    <dbReference type="OrthoDB" id="529205at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0023399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="146" mass="16379" checksum="6DB1D540AA6114AD" modified="2023-09-13" version="1">MTLLSRYLRPSLVSRMKTAAPLAAVVPRSFTTSFQSSRVDLMKQAPGWDASNATESEADVKADRERLTNMKQLQEDSAQYAREHQPVKIVTVEASPILGMDIAVEEVVDDFARRAQQTSDEKLDKVEKKLESFEENIEGSPIFGYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T4H6</accession>
    <name>A0A9P6T4H6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Bola-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003092</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BolA/IbaG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000018">
        <property type="protein sequence ID" value="KAG0024424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T4H6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051604">
        <property type="term" value="P:protein maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.90">
        <property type="entry name" value="BolA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045115">
        <property type="entry name" value="BOL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002634">
        <property type="entry name" value="BolA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036065">
        <property type="entry name" value="BolA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12735:SF27">
        <property type="entry name" value="BOLA-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12735">
        <property type="entry name" value="BOLA-LIKE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01722">
        <property type="entry name" value="BolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003113">
        <property type="entry name" value="BolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82657">
        <property type="entry name" value="BolA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0024424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="90" mass="9831" checksum="3A105A6B2250D4D6" modified="2023-09-13" version="1">MSAPVTSVTLESLTKACNERLGAIHVEGQDISGGCGQNFEITIVSPIFEGKTTLQKHRLVNEALKDQIALVHAFSQKALTPEQWKAQQQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T5F1</accession>
    <name>A0A9P6T5F1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004013</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000021">
        <property type="protein sequence ID" value="KAG0024347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T5F1"/>
    <dbReference type="OrthoDB" id="2405996at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="287"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="324"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0024347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="380" mass="42510" checksum="6E01F24C040D700C" modified="2023-09-13" version="1">MTQILESTRNYLKSSTKLGRRVSGSPDVTSGSETSLHDNNFPISKDGSPRQKKHLSSGTNTPEGRKSPTPNEHPIAYDDATLSYHQRALKNSKSFRSTKSRGASEHMEDEVPRGRSPTLSMSNTFSTAASSYDMRPSDYPNIRQYQAHIWRRNLLEESIMHSLRLGYGDRSRPPSRHQSRSSRIDSTRSRKTREMGVLAATASQENIIDRSLKNLENRPEQQQPQQFRREKNGPYQLDYNMSMTNITQSFASFTLELPHHQASHVMASSVIPDLFRVKAIIPGVYRPRSRRNSRSSVNSGITPSPRVLNGKKAKAVVPLPQLALPDVVDEDEDTESPLTPTSSVWSESVLESLEKVSGTKKDPIVESRLKALEMAPATAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MDL6</accession>
    <name>A0A9P6MDL6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008259</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004421">
        <property type="protein sequence ID" value="KAF9993150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MDL6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="69"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9993150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="106" mass="11328" checksum="551A103DDBCDE18A" modified="2023-09-13" version="1">MTYRPPATPRKSNESHKRTTGAKSVAGSPRLSDSDDTSSLHDDEPRMLDEQVFTQKPRDPRPSSSSQGDAADNVAASSSNANTNPSTVPDAAEVAPLSNQFHSHQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MDM4</accession>
    <name>A0A9P6MDM4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Lipase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_008246</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004407">
        <property type="protein sequence ID" value="KAF9993191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MDM4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016298">
        <property type="term" value="F:lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002918">
        <property type="entry name" value="Lipase_EstA/Esterase_EstB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32015">
        <property type="entry name" value="FASTING INDUCED LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32015:SF1">
        <property type="entry name" value="LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01674">
        <property type="entry name" value="Lipase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9993191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="216" mass="23254" checksum="7B2F4F862024E410" modified="2023-09-13" version="1">MVKRGYCVFGLTYGIYPPLTSFGGLAPIEDSAREVGNFINDVLAKMNVTQVDVVGHSQGGIIARYWMRYLDGAGKVHTHVGVSGINHGTTLDGIATLGKVLGIFNSVQPLFDSVAPSLFEMVTNSPFMNKLNEGSDIVPGVTFANIATKLDEIVTPYENCYQNDTGVTNALLQDFCSVDLTEHIFMPGSSVVLQFVLNQLSPSTAVRPNCFSGLIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MDX1</accession>
    <name>A0A9P6MDX1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_007806</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004064">
        <property type="protein sequence ID" value="KAF9994445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MDX1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9994445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="311" mass="34391" checksum="4C1D0CBFB1B5440F" modified="2023-09-13" version="1" fragment="single">VQGKPADLPEVPEKFTSPNFKEMFMYARTELMKTSLLKRSKSKVFVIDKDVLVALSGIVNTLLPVALQTFTIASTVKSQSLLPELTQRQPAVEDLLRDLLSALCPGISEDPYTEPTLWGLQGRVWELLSQMGKGTEPKSKDEKVRLAVLMIINHLCGMISSNQLSPPTSEHVSVSVWSFTMGLLFGGQAIRVIPTDTNPVMSTGELGSSATKNARLLVENEFGTTTKYVCGRKVDLSVRIFADFSWENEISIYEFKSGTVADDSCEQQQRKAVRLNAAILLELEKQGVDITKVFPVIAEGRGLSMDLYTLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ME30</accession>
    <name>A0A9P6ME30_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Condensation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007836</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004091">
        <property type="protein sequence ID" value="KAF9994349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ME30"/>
    <dbReference type="OrthoDB" id="416786at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043041">
        <property type="term" value="P:amino acid activation for nonribosomal peptide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19544">
        <property type="entry name" value="E-C_NRPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensation_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF1">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Condensation" evidence="1">
        <location>
            <begin position="10"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9994349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="358" mass="39430" checksum="3CBEE2AAC58F6C63" modified="2023-09-13" version="1" fragment="single">MSFDGRDILDRYLGAVQKVIDRHDILRTAIMWKNLSVPAQVVLRHAPMPITELSLNATDGPMLDQMTRLFDPRDHSIDLTQAPLIRFAIAQNTDGTWIAFQLMHHLIGDHSTLEVVMKEIKIFLDGRAESMLLPQPFRNLIAQARSGPGAETHAHFFKEMLAEIDTPALPYGFSDILLDGTDITESYREIPQELNDRLRSHAKKMGVSLASFCHLAWAQVVSRTSGQERVVFGTVLFGRMQGGSGADQAMGLFINTLPLRIDIGGSSVVESVHKTQASLAQLLEHEHASLALAQRSSSISAGTPLFSSLLNYRHNSDILHKGSVIAGLKVLAEDERTNYPFVMNVEDGGSTLGLTAQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MEA8</accession>
    <name>A0A9P6MEA8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007751</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004018">
        <property type="protein sequence ID" value="KAF9994654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MEA8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="228"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="234"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9994654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="260" mass="28395" checksum="6DE4D0452FC2B9B0" modified="2023-09-13" version="1" fragment="single">KYGALEKASQDLGNSKVEANVEKRNSLLDTVQQLQLTNEVFRKQLMDTINYVQLRYLTQVLDAAEHITSQKQTRAMSNSFLSDMLSRGVKKTGPLQPKNTCTMATQTPPAASTSLQLRQQQLLQQQVLRQLNPSEGKLSKSFTFSSSLFNLTGNNDENGIKYKLRGGALSYDRSQVSCQPIPPVVVREPDSPDSVDILAVNRGDVSTLTFLYASPTTSQLHIVVPDDPSERRTISNAGGSQAGSVHHDVVGTTSTLSVDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MG89</accession>
    <name>A0A9P6MG89_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006924</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003458">
        <property type="protein sequence ID" value="KAF9997790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MG89"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9997790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="208" mass="23424" checksum="A908E87F0544FC2D" modified="2023-09-13" version="1" fragment="single">MSASPAYLRWALEKKKKARSTVSATRDFESLLNLNNIRSHRRKKLANAFKYFQAHHQERFWAERALEVNTEVAVKRAGTIMQDAGVNEAKMACERFFSNNEGRSLEMDLVDDSEGESGSESESSEGRSREADLVDDSKGESWSESESKREEEGTAISSKVYAGVETPEPATKAPVGEDDAELLEDLEQQLTRAKATPFYDLIKYVFNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MHY9</accession>
    <name>A0A9P6MHY9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Disintegrin and metalloproteinase domain-containing protein B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_006230</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Probable zinc protease.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003068">
        <property type="protein sequence ID" value="KAG0001130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MHY9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.70.10:FF:000003">
        <property type="entry name" value="Disintegrin and metalloproteinase domain-containing protein 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.70.10">
        <property type="entry name" value="Disintegrin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001762">
        <property type="entry name" value="Disintegrin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036436">
        <property type="entry name" value="Disintegrin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001590">
        <property type="entry name" value="Peptidase_M12B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003903">
        <property type="entry name" value="UIM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11905">
        <property type="entry name" value="ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11905:SF159">
        <property type="entry name" value="ADAM METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00200">
        <property type="entry name" value="Disintegrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13688">
        <property type="entry name" value="Reprolysin_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00050">
        <property type="entry name" value="DISIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57552">
        <property type="entry name" value="Blood coagulation inhibitor (disintegrin)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50215">
        <property type="entry name" value="ADAM_MEPRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50214">
        <property type="entry name" value="DISINTEGRIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50330">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040322261" description="Disintegrin and metalloproteinase domain-containing protein B" evidence="7">
        <location>
            <begin position="29"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="741"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M12B" evidence="9">
        <location>
            <begin position="310"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="domain" description="Disintegrin" evidence="8">
        <location>
            <begin position="550"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="807"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="467"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="466"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="470"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="476"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00056552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00074021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0001130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="847" mass="91548" checksum="8EE5FE7B4DFA01E6" modified="2023-09-13" version="1" fragment="single">MVTSIRANLLALLSILAVSTTLTNTVQAHSSAWPTIIRSEHIHNLRHDILPRTHSNPLAKRNTDYSDIISRHDTIRLQFSAFNTTFHLYLEPNTEFIHPDASLGPDVFHDDIKAFKGIVIQDEQHSDHKWHRAATTSRIAKRTVEHMLHEEGVLGWARMMVEHDADSTEGLILRGAFMINDDTYHITTRQNYHIQKRSDDASPSQTASGSSLVIYRDSDFYKPASLSRKKRGITADEVSCGADHLDKTAEYIEATSSHDYYYPPDSRMTVPMMGGVDTTSSWVDVLKMPLIKRDVNVTVAGPDPVPTGCPVNRLGVAADCAYVRSYGGQVAARKQIFADFNTASGIYESTFNVALGIIALNITSENCPTTPVQGEEWNQDCSTAYTIDMRLSDFSKWRGQGDRVNDGAGLWHLMTKCNSGSVVGIAWTKALCQMESQAQSTSEGTQYTAGTGVSSITTNEWMVVAHEVGHGFGAIHDCTASTCPAQAGVCCALSSTTCDAGGAYIMNPSEQTATKVFSPCSIKAICGTIASSSGQCLKTPGTRETQSSEENICGNGIKETGEDCDCGSTEDCANDPCCDGTTCKFKNGAVCDGMNDDCCLNCQLRPAGEVCRKAISGCDIEEVCTGINATCPPDVKVADLTSCTGTGNMTGLQCANGVCTSRDLQCQQQDRAGITGQCEASTSCQLMCNDPNGNALSCTQIPGTNFIDGTPCGFGGTCSAGNCKYNGINGVLSWARSHLAIVIPVACVVGLLLICCIWSCCCSGFFYRQRQKKMLRKPSARRPYDAQPGVDTAPGRFGSNAVHNSQHIGQGYAMGPLPPPPVYHDPSVLVREREEEELQRALEESRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MI12</accession>
    <name>A0A9P6MI12_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Structure-specific endonuclease subunit SLX4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_006207</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLX4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003055">
        <property type="protein sequence ID" value="KAG0001275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MI12"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033557">
        <property type="term" value="C:Slx1-Slx4 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000712">
        <property type="term" value="P:resolution of meiotic recombination intermediates"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018574">
        <property type="entry name" value="Structure-sp_endonuc_su_Slx4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21541">
        <property type="entry name" value="BTB POZ DOMAIN CONTAINING 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21541:SF3">
        <property type="entry name" value="STRUCTURE-SPECIFIC ENDONUCLEASE SUBUNIT SLX4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09494">
        <property type="entry name" value="Slx4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="41"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="122"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="44"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="66"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="89"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="164"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0001275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="290" mass="32403" checksum="E051E3386F57E5C7" modified="2023-09-13" version="1">MPDYNNMSVARLRLAATTFGLKANTKRLLVDQLTAIWESVNAERDDEEGQEQNENEDENQNNSEIEQVDDSDDGGPDTNGYESDNLDSLGDRDRDCRSRKASSSLAAEIPSSQFSLGMDGISNLDYDMGPPSDVAEGSTSHNRRRPLHALAYSIGGARESPVVSEEEEQSSGGEATEDEDEDTSSLAGIDSEYEHMSVSQNERSENTPDLERQLYAFLSSATHLRKQFLTYKPLDLEQVWEECQALDITCTRQQLQRYLDQQGIINVVPARSKLKSWRSARAAKQKRVAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MJ08</accession>
    <name>A0A9P6MJ08_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005989</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002953">
        <property type="protein sequence ID" value="KAG0002364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MJ08"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0002364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="89" mass="9676" checksum="F45AFB54DC75E69E" modified="2023-09-13" version="1" fragment="single">MDNGTSSSQGSSRPSSYHGSAHSSYYSKSSTQTDSTAGTKKNGSNVKETGPKVPTTPEERYRIVDDILETENLYRVLAVSRTATSEEIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MKN2</accession>
    <name>A0A9P6MKN2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cell cycle checkpoint control protein rad9b</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">RAD9B</name>
        <name evidence="3" type="ORF">BGZ80_005213</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002587">
        <property type="protein sequence ID" value="KAG0006588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MKN2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030896">
        <property type="term" value="C:checkpoint clamp complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071479">
        <property type="term" value="P:cellular response to ionizing radiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000076">
        <property type="term" value="P:DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031573">
        <property type="term" value="P:mitotic intra-S DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03572">
        <property type="entry name" value="ENTH_like_Tepsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.70.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046938">
        <property type="entry name" value="DNA_clamp_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013809">
        <property type="entry name" value="ENTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035802">
        <property type="entry name" value="ENTH/VHS_tepsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007268">
        <property type="entry name" value="Rad9/Ddc1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15237:SF0">
        <property type="entry name" value="CELL CYCLE CHECKPOINT CONTROL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15237">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01417">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04139">
        <property type="entry name" value="Rad9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55979">
        <property type="entry name" value="DNA clamp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ENTH" evidence="2">
        <location>
            <begin position="19"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="741"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0006588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="741" mass="82621" checksum="86F58DA846623C26" modified="2023-09-13" version="1" fragment="single">MNQITQTTKSTINTIKAHALLAKALSNDPKPTPGYLFPEIARLTQSPGTSTVVLSQLLKTLTSSGGSSSSNSQAIGSTTGTTPTYTNSPHVLLKALKILRQLVQSGSVEFKTNLARRGKDILAKMVGYRGEWDEVHGDKFNEDVRTVAEDLLEYMHANPVQEQDDPDLTDREAAVLKNSTQDLQGFGNPEYDDSDSEDNMSQKNATRGKKKATAKATPPLPGFGNPAFEKDIDYTEPTLMSRLVDRLQEMTAPPPPMTMRAAHRQQEQRRQKLFVGEYSMRTDAHSRSKEGPIILMGTNPFKRTTRTQGLVAGGWGEKTVDSSGMSTQDYITSRVFPQYRSGTRSIQFRNPMAEAVYKLAQYIETGLVRSKFQSQLLTRDGDARSSDLMDTTASLPTHRDFSSETLLFWGTSKDISDVVLEHLASEKSATLVDHLGDDKPSNPSQRVSAMTGFVRDMIDWIEQEDWERRIRYLFVLDVLLAHPEIEGELLNCSALPMLSKTLAGPMCLEAPQRSVRVLSTQLESFQAVLTCLAKIGDDIVVEARPDRFILSTINITRSAFATFTFTRTFFESYHLDITAEAIKHDASGPYLRCTVLAKALVSACKIRGNVEQKIEKCCLFMNAAEGVGENCRLTVEIIFKYGKWEWNGNKNIREASDLRLNKHQRFIKIHKLLYESCPEPLQVIDSIESCPSSWRLPAISLIGFTENFSSKAEEITMTCTQEGITFKTFMDTSEEDSGGSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMZ9</accession>
    <name>A0A9P6MMZ9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_003788</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002019">
        <property type="protein sequence ID" value="KAG0008159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMZ9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0008159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="60" mass="6683" checksum="B0554E9959759F17" modified="2023-09-13" version="1" fragment="single">LINQSSLGESLAVVTMLSFAIPQCSMREYFPRKRNTVMSIGKDSKMVLEEGDQTTDPFSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNJ9</accession>
    <name>A0A9P6MNJ9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_003121</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001807">
        <property type="protein sequence ID" value="KAG0008731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNJ9"/>
    <dbReference type="OrthoDB" id="2439595at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90257">
        <property type="entry name" value="Myosin rod fragments"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="43"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0008731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="424" mass="49057" checksum="E8A2094DC42F98C6" modified="2023-09-13" version="1">MEVDQEPLTRDPTLTKNIPSNHHPKEMPGNISSKVNRAEQKHVQTLQRKLNDVSIRHQETEKHCRKLSDDNQRLENQLSCALARNQEMEEHCLQLFDDKQRLENQLSHALARNQEMGEHCLQLFDDKQRLENQLSHALARNQDTMATLERLQDAHAYLIRQNDDLKRKYTKKVESYKELDKNYMDLVRPLQVSGDDYSTIYSRLMHIRVSIENLIQKARGDGSANLNKEAAIEHFRGSNLLEEFPVDESLLESYHLNLYMESAIMTGLIERLFNRALACIFDQSEEFEKISRWVDNRDNKIAVRWRQQLCVLAARDSDAMKCRREREVNEAATVLSSLVTRVYPNVDMSIKIKKLCYNAFDLSFAMFGMESIIQPASTPLGVPFDDINMTTPQKSNPTGIVSLVIFPAFRDNAAFNITPKVWCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNL8</accession>
    <name>A0A9P6MNL8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">mRNA export factor GLE1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Nucleoporin GLE1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_003295</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GLE1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001865">
        <property type="protein sequence ID" value="KAG0008564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNL8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044614">
        <property type="term" value="C:nuclear pore cytoplasmic filaments"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000822">
        <property type="term" value="F:inositol hexakisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031369">
        <property type="term" value="F:translation initiation factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016973">
        <property type="term" value="P:poly(A)+ mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.510">
        <property type="entry name" value="GLE1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012476">
        <property type="entry name" value="GLE1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038506">
        <property type="entry name" value="GLE1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12960">
        <property type="entry name" value="GLE-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12960:SF0">
        <property type="entry name" value="MRNA EXPORT FACTOR GLE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="7" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0811">Translocation</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00026227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0008564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="79" mass="8951" checksum="7F135ED07F73E8EA" modified="2023-09-13" version="1">MPPRPITPALIAVFIEVCGNMYLGTYRNQANKVLRLLYEDFLPMIPKQGIDGKVRLKTLLDDFIKSGQIPVADGREFDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNV8</accession>
    <name>A0A9P6MNV8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mitochondrial atp synthase epsilon chain domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_002851</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ATPase epsilon family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001725">
        <property type="protein sequence ID" value="KAG0008986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNV8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042776">
        <property type="term" value="P:proton motive force-driven mitochondrial ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12153">
        <property type="entry name" value="F1-ATPase_epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1620.20">
        <property type="entry name" value="ATP synthase, F1 complex, epsilon subunit superfamily, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006721">
        <property type="entry name" value="ATP_synth_F1_esu_mt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036742">
        <property type="entry name" value="ATP_synth_F1_esu_sf_mt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12448">
        <property type="entry name" value="ATP SYNTHASE EPSILON CHAIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12448:SF0">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT EPSILON, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04627">
        <property type="entry name" value="ATP-synt_Eps"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48690">
        <property type="entry name" value="Epsilon subunit of mitochondrial F1F0-ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0008986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="65" mass="7501" checksum="CBBD92CA78E08C09" modified="2023-09-13" version="1">MSHFWKPTFTYLQYAQICARTVRNSLKEEARVVAVRRDEQGLKFAKWEAGKQGDLKNTVGNRTVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQ44</accession>
    <name>A0A9P6MQ44_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATP-dependent DNA helicase CHL1</fullName>
            <ecNumber evidence="17">5.6.2.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">ATP-dependent DNA helicase chl1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="16">Chromosome loss protein 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="18 19">DNA 5'-3' helicase CHL1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="24" type="primary">DDX11</name>
        <name evidence="24" type="ORF">BGZ80_002233</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="24" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="24">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="20">ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M. May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres. Has a specific role in chromosome segregation during meiosis II.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="24">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.3" evidence="17"/>
    <dbReference type="EMBL" id="JAAAID010001546">
        <property type="protein sequence ID" value="KAG0009597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQ44"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034085">
        <property type="term" value="P:establishment of sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18788">
        <property type="entry name" value="SF2_C_XPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006555">
        <property type="entry name" value="ATP-dep_Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045028">
        <property type="entry name" value="DinG/Rad3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014013">
        <property type="entry name" value="Helic_SF1/SF2_ATP-bd_DinG/Rad3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006554">
        <property type="entry name" value="Helicase-like_DEXD_c2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010614">
        <property type="entry name" value="RAD3-like_helicase_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013020">
        <property type="entry name" value="Rad3/Chl1-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00604">
        <property type="entry name" value="rad3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472:SF41">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE DDX11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472">
        <property type="entry name" value="DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06733">
        <property type="entry name" value="DEAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13307">
        <property type="entry name" value="Helicase_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00488">
        <property type="entry name" value="DEXDc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00491">
        <property type="entry name" value="HELICc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51193">
        <property type="entry name" value="HELICASE_ATP_BIND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="15" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="9 24" id="KW-0347">Helicase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="13" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="23">
        <location>
            <begin position="26"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="22">
        <location>
            <begin position="84"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="22">
        <location>
            <begin position="157"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="22">
        <location>
            <begin position="541"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="22">
        <location>
            <begin position="677"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="22">
        <location>
            <begin position="84"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="22">
        <location>
            <begin position="110"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="22">
        <location>
            <begin position="157"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="22">
        <location>
            <begin position="196"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="22">
        <location>
            <begin position="541"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="22">
        <location>
            <begin position="677"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="22">
        <location>
            <begin position="689"/>
            <end position="698"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00029709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00044969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00044998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00045008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00045702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00048954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS51193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="KAG0009597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1064" mass="119547" checksum="EBCEB7553BF10B86" modified="2023-09-13" version="1">MHTWDLFKEDNLEKYRESEEPLPTPNSFPAFPYATPYAIQVEFMQQLFECIDQRKVGIFESPTGTGKSLSMICGAVGWLMERERAEKEGAEKDREGDAEKKWSHAKEGDNSTAVKSSANDDTPDWVQQHREVSDAAIERQEREARRMELEARVKRIRDREKKMRENMSRRMKRQATGTSGFISMAGQTKKKKDQDPDKEDMDDSAFLVDEYDSDDNKRGNGKGKSGANDYSNVSKEVLELLKSFDAREAEHGQKRTGFGLDDEDQEPDVLKIYYCSRTHSQLSQFIDELRKTSYGDHLHVISLGSRKSLCINERFRKLASFKSNKTAEPIVNVNKLNDACLDAQKSGTPTDQRCEFLHMPTMSFGSKARGGIGAGNDDDDEPSSLSKNEWWKSDVIDSDEKLLDFRDNTLARIRDIEELAELGTELETCPYYGSRQTVRHCQLVTLPYNLLLHASTRESLKLVIKNNILLLDEAHNLINSLLQMHSVTLSLQQIQLSQEQLRVYLGRYEKRLSATNESYIRVLLRILKCLEGFVEKWKAGPSQSQQTQAPVSTPQQSNRATRPVDRVMKVNEFLHDAGMDHINLFKAHAYLDTSGVARKLQGLHESLQRKEAKRLAKEDEKPIVKIHPGRAGFSKINTQQPPRQGTTTPILLTVDAFLMSLLNADNDGRVIMTMEEEASGAGDDGEDTVQPSSATTEPASLRSRNPVLKFMLLNPANVFKPLVDEARSVVLAGGTMEPVSDLLSHLFPYLKDSSAVSCDTVQSTVASYPKIQRFSCGHVIPKENLLTLVMEKTPTGGSLELNFANRTLSQVMDGVGQSLVNLLGVIPDGVVVFFVSYSYMAQVLARWQIKVTTSSGTVAANTIMERIQSRKRVFVEPREATEADRVLKEYQDCILARPEHETPTPGSPRGAVLFSVVGGKMSEGINFSDRLGRGVVMVGMPFPNKGSAELQERMRYMDQVQQQELQQLQGYSSISAPSRMTAGNEYYENLCMRAVNQSIGRAIRHQNDYAVIVLMDKRYGVPRIQKKLPGWIGSSVEICEQFGPVIGKISGFFRKKSVVPTRMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MR68</accession>
    <name>A0A9P6MR68_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Translational activator for mitochondrial COX1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">MSS51</name>
        <name evidence="3" type="ORF">BGZ80_001148</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001258">
        <property type="protein sequence ID" value="KAG0010829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MR68"/>
    <dbReference type="OrthoDB" id="5282002at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046824">
        <property type="entry name" value="Mss51-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032717">
        <property type="entry name" value="Mss51_Znf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28069">
        <property type="entry name" value="GH20023P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28069:SF1">
        <property type="entry name" value="PROTEIN MSS51, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20179">
        <property type="entry name" value="MSS51_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13824">
        <property type="entry name" value="zf-Mss51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mitochondrial splicing suppressor 51 zinc-finger" evidence="1">
        <location>
            <begin position="103"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="Mitochondrial splicing suppressor 51-like C-terminal" evidence="2">
        <location>
            <begin position="252"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0010829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="455" mass="51510" checksum="4E807D72C2589FA6" modified="2023-09-13" version="1">MASRIRPLAPALRTLPRTGVVATTARVPSAATTAANVAAQSAAAARRSLSLKSFFSSRKPKADQFTSQFEPVLEQANLFHPLSKSPLPAVRAKAEWIEAHGSCPVCKEHSPEQKSKAPKYECPDCGYPTHCSEEHYNMDKEHHKHYCGVLREVNEDEHDLRSGRRMKEFEFPGAQHRDEAINLSNWDTFLYTRGFLSMNSERSMRHVSHVLTYPLTIGSVLHQSSPYRLGKDLTVEGLKSLAALRHTLHPAIISGITQSHDLRSTATHTVRIFCLGARAESHLPPHIYMQLAYLFPSTAFQIHFVGPDAIPPHTKSKEPHQHVHYEQLTFVYDSSRYEAYHAEAGPFNPYYDVFFLFSPGLAHPATRDMWKPTIPLLLDTKCAIFGTGFDEQDVMNDVNEIENAGYELDWLMKPRENAFRSLKHEVNLTDVRQSALCNWGIWGIRGRRYDVRPAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRL8</accession>
    <name>A0A9P6MRL8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Galactose oxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_001361</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001305">
        <property type="protein sequence ID" value="KAG0010584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRL8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093:SF18">
        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00612">
        <property type="entry name" value="Kelch"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="157"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="32"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="61"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="107"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="158"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="207"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="249"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="294"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="324"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0010584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="702" mass="74946" checksum="8BB247267C525870" modified="2023-09-13" version="1">MAPVTGGGSNLEDTPPGSPTTPIAPFLAQYGQQQQQLQLQLQQRVYSPPPSNRSPAASRAFGQSSPGIEPSSTTLSSPIAAPGADTSINSIGSNQSFSSLNSGSQGPNTSINDGPGSIISNSILTTVVSQSMANSPNNGMNSNTSFFSFNKQGGARGISNNLSPLSPTGSPTLQQDQVPGSNTSSPNVSVAITRPPMSSQRNRDISSKNASHSHQSHANTSFSSVGSAEGQSPTIVTPGSIVPAAEIATQETPSMTQAVKPTMSSTTAMADASQSATVASGSQTATASHARAPSQGSTSRSSQATLVATSAPSPPPHRSHRQQQDSSQGRSRSNHSSNSQNQGHGHGLNTSSSKRHRQKASNKETTRPSATVAPAPTPAMHWTRAKVHGQSPPKELRAQTVNLVGESIYVFGGCDAKTCFNNLYIFDADTMHWSQPKTFGSIPPPCRAHSSTLVDNRRLYVFGGGDGPHYFNELYMLDTDTLTWTNPQTTGTRPCRRRAHTTCVYNNCIYVFGGGDGVQALNDTFQLDLATMHWSEVRTTGTIPTSRGYHTSNLIKSHFIVYGGSDGHECFSDVHILDLDTKVWTKIDINRTLPRLSHSATQVGSYLFVVGGHDGSRYSSDVLMLNLVTWSWETRRVYGIPPAGRGYHALLLYDSRLFMFGGYDGQTVFDDIYILDLSTCAYLPQITDFQISIQPSELALVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRS2</accession>
    <name>A0A9P6MRS2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Palmitoyltransferase</fullName>
            <ecNumber evidence="10">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BGZ80_000921</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="10">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the DHHC palmitoyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="10"/>
    <dbReference type="EMBL" id="JAAAID010001202">
        <property type="protein sequence ID" value="KAG0011139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRS2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006612">
        <property type="term" value="P:protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22883">
        <property type="entry name" value="ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0564">Palmitate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="111"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="363"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="442"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="12">
        <location>
            <begin position="317"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="173"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="255"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="618"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="663"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="188"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="278"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="628"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="663"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="680"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="716"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="734"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="749"/>
            <end position="769"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0011139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="828" mass="90698" checksum="D2016CED98C56F13" modified="2023-09-13" version="1">MAAEGGSQSGLTISRSLFPTADTTTSQSVVNTYPMQELLTGEPRQNEHTVGVSPEERINGLETLHEIDMLKEGIHEQRPRRRFRIISKALPFLLSALTIYIYYVYTIQVCILYLVAFNLLVILYFISYALSIFCNPGTPLNPPVKGQGLPIPTTTTPYRHDVPSIPLHSSSNGQANLDSLLPRPPQDENLSTPSTTAGHSSNAQHVGPHLASIVTTPKYPTVAVAPADQDEYGYSFSNDASESRASHISINISEGSIHENGDSSQSNGGHAEAAGGVEDNRVKIDNQEPASRSRDTSDENSSRLPIATLSISKRDGRPRWCDICKITKPDRSHHCSECNSCVLRMDHHCPWVNGCIGFGNYKFFYLFILYGSLSALWVVATMIPLLLQVLREYDNGYMANGNTTTGGDYMINTTDWNTIQSYLDKSSWEAQSEILQSFDVQWVVITIIALLLALLIVSFTGAHTSYILRNLTTIEALQNVRSTFVRVQYRKMDPAGDGNPGGLHSLSPQGDGVLPSFLSEIEFNVVMVEQGDNVWDRGSWGDNWCSVMGPTWWLWLIPYHNAEGDGIHEVYNEKVYNKLVTDALAQARMQVVTIGLQEDPAISSQNVGLGERTEAIMTAPSSPRMDSEITSDSPSINSSTNAEPTTSTAADRILSDANRRLKTTLNSNSNEPGKQLPPRKNTSASSTSRLESVNETPTPSIVLEVGSQDNYVEDIMESRSRRAGQRQDSHFDGGSTSQIVPSSDHSAPRQSSTRSQSSRQNSPKQSVSSTRRRQRTMSGSTSGSYAGPIREFGMGLGMDGIPVDSGTGLKLSSARMGLYSQLPPLEFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MS52</accession>
    <name>A0A9P6MS52_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPS21_1</name>
        <name evidence="5" type="ORF">BGZ80_000605</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Has a physiological role leading to 18S rRNA stability.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the small ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001128">
        <property type="protein sequence ID" value="KAG0011540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MS52"/>
    <dbReference type="OrthoDB" id="278325at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022626">
        <property type="term" value="C:cytosolic ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1230.20:FF:000001">
        <property type="entry name" value="40S ribosomal protein S21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1230.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001931">
        <property type="entry name" value="Ribosomal_eS21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038579">
        <property type="entry name" value="Ribosomal_eS21_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10442">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01249">
        <property type="entry name" value="Ribosomal_S21e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002148">
        <property type="entry name" value="Ribosomal_S21e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0698">rRNA processing</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR002148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0011540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="83" mass="9235" checksum="476751D09540D96D" modified="2023-09-13" version="1">MENITLETYVPRKCSATNRLIGAKDHASVQINIGDVDENGRYTGSFTTYALSGYVRAQSEADDSINRLATRDGLLSMVWSYQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSN8</accession>
    <name>A0A9P6MSN8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_000839</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001185">
        <property type="protein sequence ID" value="KAG0011225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSN8"/>
    <dbReference type="OrthoDB" id="2417251at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0011225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="157" mass="17989" checksum="24761F8A0257CA80" modified="2023-09-13" version="1">MVPEPQRQLTINTNKTFDSANYHQMHSVSHNEEHLLSANGLATKLEKLKVEQERCKAMNHDHHHHRLTSQHSTKGTLQIDQDLQKRAQETIHEILERLEHQKHESEFSTFAPGVEDNGGISGRARHTYALNPDLLKDTIYARSSLRQSHGNANLRHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTY0</accession>
    <name>A0A9P6MTY0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">GTP-binding protein ypt1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">YPT1_2</name>
        <name evidence="11" type="ORF">BGZ80_011608</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Preautophagosomal structure membrane</location>
            <topology evidence="8">Lipid-anchor</topology>
            <orientation evidence="8">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000954">
        <property type="protein sequence ID" value="KAG0012648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTY0"/>
    <dbReference type="OrthoDB" id="9989112at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034045">
        <property type="term" value="C:phagophore assembly site membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01869">
        <property type="entry name" value="Rab1_Ypt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000069">
        <property type="entry name" value="Ras GTP-binding protein YPT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050227">
        <property type="entry name" value="Rab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057289">
        <property type="entry name" value="Rab1/Ypt1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47977">
        <property type="entry name" value="RAS-RELATED PROTEIN RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0636">Prenylation</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="190"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00060489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00074496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0012648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="203" mass="22236" checksum="AB5C6E067675B6CC" modified="2023-09-13" version="1">MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELEGKTVKLQIVNAGQERFRTITSSYYRGAHGIIVVYDVTDMDTFSNVKQWLAEIDRYASEGVNKLLVGNKSDLTNKKVVEYTAAKEFADQIGISFLETSAKSATNVEQAFMTMAKQIKDRMGAATVAPAGPNKSIKVGSGQQLPAQNSGGCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUB6</accession>
    <name>A0A9P6MUB6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial</fullName>
            <ecNumber evidence="5">1.3.5.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">Iron-sulfur subunit of complex II</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="primary">SDH2_2</name>
        <name evidence="21" type="ORF">BGZ80_010792</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="19 23">
            <text>a quinone + succinate = fumarate + a quinol</text>
            <dbReference type="Rhea" id="RHEA:40523"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.3.5.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="18">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate metabolism; tricarboxylic acid cycle.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.5.1" evidence="5"/>
    <dbReference type="EMBL" id="JAAAID010000791">
        <property type="protein sequence ID" value="KAG0013882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUB6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051538">
        <property type="term" value="F:3 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008177">
        <property type="term" value="F:succinate dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1060.10:FF:000001">
        <property type="entry name" value="Succinate dehydrogenase iron-sulfur subunit SdhB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="entry name" value="Alpha-helical ferredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050573">
        <property type="entry name" value="SDH/FRD_Iron-Sulfur"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004489">
        <property type="entry name" value="Succ_DH/fum_Rdtase_Fe-S"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00384">
        <property type="entry name" value="dhsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11921:SF29">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE [UBIQUINONE] IRON-SULFUR SUBUNIT, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11921">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE IRON-SULFUR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13534">
        <property type="entry name" value="Fer4_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46548">
        <property type="entry name" value="alpha-helical ferredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="16" id="KW-0003">3Fe-4S</keyword>
    <keyword evidence="8" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="12" id="KW-0249">Electron transport</keyword>
    <keyword evidence="14" id="KW-0408">Iron</keyword>
    <keyword evidence="15" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <keyword evidence="9" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="20">
        <location>
            <begin position="48"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00016766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00033304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00049220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAG0013882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="145" mass="16645" checksum="BAF8CAD9E2EB16D0" modified="2023-09-13" version="1">MTISSLAHVVKDLIPDLTEFYAQYKSIEPFLKQKTPAPERENLQTIEDRKKLDGLYECILCACCSTSCPSYWWNSDQYLGPAVLMQAYRWMIDSRDQFGPERRQALQNPFSLYRCHTIMNCTKTCPKGLNPGLAIAEIKKAMALE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUI0</accession>
    <name>A0A9P6MUI0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nucleolar protein 16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">NOP16</name>
        <name evidence="7" type="ORF">BGZ80_010652</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the biogenesis of the 60S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the NOP16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000764">
        <property type="protein sequence ID" value="KAG0014104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUI0"/>
    <dbReference type="OrthoDB" id="285729at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019002">
        <property type="entry name" value="Ribosome_biogenesis_Nop16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13243">
        <property type="entry name" value="HSPC111 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13243:SF1">
        <property type="entry name" value="NUCLEOLAR PROTEIN 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09420">
        <property type="entry name" value="Nop16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0014104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="201" mass="22988" checksum="AC81B4E27180A96E" modified="2023-09-13" version="1">MATVRKRRTTKAPSRKVTRKNANKHKKKVNVIGNKIIRENWDKKATLRQNYARLGLLPSLNGVTGGIEVKDEAEVEENEQMTLEELAETLTEEQGIIQRDDDGNIINIIVGKAKTKEEIDEMMERDVEPVKAKTDVVRALEAQAANVLKKERYQSEGEVVWAAQLVEKYGDNYEKMFWDRKLNPNQQTVAQLKKRISALLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUV4</accession>
    <name>A0A9P6MUV4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Very long-chain fatty acid transport protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">Very-long-chain acyl-CoA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">BGZ80_010920</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Acyl-CoA synthetase required for both the import of long chain fatty acids (LCFAs) (C14-C18) and the activation very long chain fatty acids (VLCFAs) (C20-C26) by esterification of the fatty acids into metabolically active CoA-thioesters for subsequent degradation or incorporation into phospholipids. The transport and fatty acyl-CoA synthetase activities are genetically separable and are thus independent activities. Esterifies VLCFAs in the peroxisome matrix. The VLCFAs are actively transported into peroxisomes by a PXA1-PXA2 heterodimeric transporter in the peroxisomal membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>a very long-chain fatty acid + ATP + CoA = a very long-chain fatty acyl-CoA + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:54536"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:58950"/>
            <dbReference type="ChEBI" id="CHEBI:138261"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="13">Peroxisome membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000815">
        <property type="protein sequence ID" value="KAG0013675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUV4"/>
    <dbReference type="OrthoDB" id="288590at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009898">
        <property type="term" value="C:cytoplasmic side of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005324">
        <property type="term" value="F:long-chain fatty acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004467">
        <property type="term" value="F:long-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044539">
        <property type="term" value="P:long-chain fatty acid import into cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.30:FF:000002">
        <property type="entry name" value="Long-chain fatty acid transport protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12780:FF:000019">
        <property type="entry name" value="Long-chain fatty acid transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006134">
        <property type="entry name" value="PRK08279.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43107:SF15">
        <property type="entry name" value="FATTY ACID TRANSPORT PROTEIN 3, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43107">
        <property type="entry name" value="LONG-CHAIN FATTY ACID TRANSPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="10" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="18">
        <location>
            <begin position="55"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00046271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00051585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00060276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00068795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00078285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAG0013675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="618" mass="68531" checksum="0C680D2018131DD6" modified="2023-09-13" version="1">MPAVPIVAAAVPAAIYVSSKLAIPRDVKLARGLVSSKMNYRSYEKNDTINISYRFEEAFQRNPNKEAIIFEGRSYTFADVQRESNKVGNWLLSKGVKRGDIVSLMMQNRPEFLFFWLGINKIGATGAFINTNLTGKPLTHSLKTATASILILDTELTQPIAQVLDEVVQMGYTVYTFAGNGPAVDFATPVDLTGISDAALPKSLRKKTGANDIAMLIYTSGTTGLPKAGRFSHARANLAAHFWTSFYFFNENDRLYIALPLYHSAGAVLGMCVAWVTGATVVLARKFSTTSFWDECRANNVTVIQYIGEICRYLLNAPPSPLDKVHNIRMAHGNGMRPDVWSRFRDRFGIPLIGEWYASTEGTGILTNYNTGENGVGAIGYRGKLARTVDAGLKIARFDVVTEELIRDKNGRCIECAADEPGELLTIIDSTDPTRAFQGYHQNAGANSKKVVSDAFKVGDRYFRTGDILRRDKDGYFYFGDRVGDTFRWKSENVSTAEVSEVLSAYPDCIEVNVYGVQIPGHDGRAGMAAIVSKPTMDWDKFAKFALKNLPRYSVPIFIRKSPVIEITGTFKQRKVELVNEGIDPNKIPDEMLWLDGQSYKPFKSAEHTRVITGKAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MV71</accession>
    <name>A0A9P6MV71_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Mitochondrial carrier</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_010771</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000789">
        <property type="protein sequence ID" value="KAG0013896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MV71"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000064">
        <property type="term" value="F:L-ornithine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990575">
        <property type="term" value="P:mitochondrial L-ornithine transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050567">
        <property type="entry name" value="Mitochondrial_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624">
        <property type="entry name" value="MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624:SF57">
        <property type="entry name" value="MITOCHONDRIAL SUBSTRATE CARRIER FAMILY PROTEIN L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="37"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="132"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="227"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0013896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="321" mass="35583" checksum="73B5A3ED0A1483F8" modified="2023-09-13" version="1">MSAPSSAPLGVVEPGSVPSAVVAATKDKLSANDKTNQKNVHGFIAGVFSGVTKMAVGHPFDTMKVRMQTAGNNRFHGLWHCVTETLKKEGPRAFYKGATPPLIGWAFMDSVMLGSLSYYKLILQGGDPNVKLTPFWCGIAGIGAGVTVSFVATPIEHVKARLQVQYDAKTKIYAGPIDCARQLVRNNGITGLWKGLVGTLWFRSSFFVWWGSYEIYSTEMRKRTNMSEAAINFWAAGMAAQSFWFFAFPCDVVKNKIMTQPDVKNPPFPTLISGFKHVYRTDGLRGFYRGFLPCFLRAFPTNACALTSFELAMRWLRKMEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVC4</accession>
    <name>A0A9P6MVC4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_010793</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000792">
        <property type="protein sequence ID" value="KAG0013865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVC4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051179">
        <property type="entry name" value="WD_repeat_multifunction"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19857:SF8">
        <property type="entry name" value="ANGIO-ASSOCIATED MIGRATORY CELL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19857">
        <property type="entry name" value="MITOCHONDRIAL DIVISION PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="189"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="50"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="63"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0013865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="338" mass="37730" checksum="1049ADBD73234BBD" modified="2023-09-13" version="1">MSTAASPPKREREEAAAASSEEDYFTPDSSPAPFKKPKSPSSLNETSDHASPPDSSASPAALESNTTSGDVSESQSEQLERIFKNLRLRRIVKENHSSEINQLAFCLNQRHNRTPFGLDQVKVFEKRGAVKRDPMDNSNILGTTGGPQANIYDNEHCGDHLDIMSHFLLDPSGEEGAEELPAHPTKDEYLLSASKDGTVRMWNILTGKCLLIFEYKASVTCFIPSANGRVFLTGSYNGEVRKWNVPEFESEPEEPIVVLDELFFCAGTSNGSVYIYNIDSGKTVTELKHRRSTKAIRTCIFARDSRTVICAGEDSFIWRYDYVTDDTLNEWATWKPEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWC9</accession>
    <name>A0A9P6MWC9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Copper transport protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BGZ80_009439</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 11">Membrane</location>
            <topology evidence="2 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000566">
        <property type="protein sequence ID" value="KAG0016088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWC9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005375">
        <property type="term" value="F:copper ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08554">
        <property type="entry name" value="Cyt_b561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007274">
        <property type="entry name" value="Cop_transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043205">
        <property type="entry name" value="CYB561/CYBRD1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006593">
        <property type="entry name" value="Cyt_b561/ferric_Rdtase_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10106">
        <property type="entry name" value="CYTOCHROME B561-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10106:SF0">
        <property type="entry name" value="LD36721P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04145">
        <property type="entry name" value="Ctr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03188">
        <property type="entry name" value="Cytochrom_B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00665">
        <property type="entry name" value="B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50939">
        <property type="entry name" value="CYTOCHROME_B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0186">Copper</keyword>
    <keyword evidence="11" id="KW-0187">Copper transport</keyword>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4" id="KW-0349">Heme</keyword>
    <keyword evidence="11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="24"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="101"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="197"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="240"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="280"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b561" evidence="12">
        <location>
            <begin position="167"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU367022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0016088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="379" mass="42055" checksum="4EFEC0ED6CA15C65" modified="2023-09-13" version="1" fragment="single">MTLHFSLGDNILFSSWMITSAGGYFGSIIFTIFLATLRVVVSNYVFKLQEKKRKLIEEKAQPVVRLSRSQLYKERLPLATIGAFESFLSWVLMLIVMTFNASLLFSAVAGSFIGFLFFGRNGLDDDCGCGDISQTEDISQAEDITQAEDDVPSGNSSMPYPVARSILPRIVGVAFLVILFLWIYQAEGGIGFQEATVFGWHALFMSLFVVVFTQEALLAYSSPLIGFFTKNRTMIKYYHVICHLLGLIYAVAGLVAIVYYKRLSPQPTVFPFYSVYSPHSWAGIVFLSLWSLQLLAGLYVYIGGKRQSASQKRSFRKLHGFLGKSVYVVGLASCAMGFQDMQSSDLASSTPPSSANMTMSMEDMQGYFPDSNLAQYSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWD0</accession>
    <name>A0A9P6MWD0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Adenylate cyclase</fullName>
            <ecNumber evidence="3">4.6.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">ATP pyrophosphate-lyase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Adenylyl cyclase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="primary">CYR1_1</name>
        <name evidence="17" type="ORF">BGZ80_009383</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP = 3',5'-cyclic AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:15389"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58165"/>
            <dbReference type="EC" id="4.6.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the adenylyl cyclase class-3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.1" evidence="3"/>
    <dbReference type="EMBL" id="JAAAID010000557">
        <property type="protein sequence ID" value="KAG0016177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006171">
        <property type="term" value="P:cAMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17214">
        <property type="entry name" value="RA_CYR1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050216">
        <property type="entry name" value="LRR_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000159">
        <property type="entry name" value="RA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055071">
        <property type="entry name" value="RA_PHLPP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051:SF1">
        <property type="entry name" value="RAS SUPPRESSOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23010">
        <property type="entry name" value="RA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00364">
        <property type="entry name" value="LRR_BAC"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50200">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0115">cAMP biosynthesis</keyword>
    <keyword evidence="5" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="10" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Ras-associating" evidence="15">
        <location>
            <begin position="360"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="domain" description="PPM-type phosphatase" evidence="16">
        <location>
            <begin position="1089"/>
            <end position="1346"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="14">
        <location>
            <begin position="1393"/>
            <end position="1532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="172"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="238"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="76"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="126"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="205"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="238"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="17">
        <location>
            <position position="1736"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00032597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0016177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1736" mass="193327" checksum="8948CAE5A2DFF37C" modified="2023-09-13" version="1" fragment="single">MNQSNSAIAASSATLHSSNTTLHSNSSSTYFHSNNGSKHGSSSNLSSSFGNGQQSYQYRPAPHPFSPDSSRRRSTEYYSRSPSPDQFQLQQQQQSAISGKHQFPTTPPFHNRSHQRAESLKSASEAPHRRTKSTDFGDMNSKRPGLPQELADLQASIASPAKETKKTIFSIFKKKSQGSTPPSPNPPTSSSSHDYNSRKYSADDSPLMLSPPSSLSVQSFSTLTDQDSALMQGYSFDRRHGSDGGDSQRHLPPFSIGKKNSKKDIISHDPILPGFVVDQGDVMGLTGIKDDPKNGQWLLPSAASGADWHAPESWGVQSIAAPIGPLQKSLTSTSEDVTSDEVEYSDYESWNYDQKKRSAVRIFRPDTTYTTVNCECNIKASELSAMLARKIFKPDTSKYHLYIERNNIVRPLSPNERPQYILRRCLLEFGYTDQDKLDELSGKDNSFLCRFTFAENGVPHITEADFPAHTIYTDVNLQRRCLPTIPIFLYSRAKDIRQLNISHNQRMDLPLDFIQNCTALKELRMAYNDLVKIPSNVRYIVNLQLLDARGNRIRDLEKAHLDQASKLHTLILQCNRLDSIPSSFAAFQNLRTINLSSNNFKKFPDILCSVISLEELDLSFNDIGGIPVDISNLVRLKKLLLYGNKIMPYLPKSMESLVSLRKLDIRQNGLLNLDVLNDLPALEELLVDYNTNVILNNTFRALVRASIVKCNMADVNLRGTGDTLVFLDLSSNKLSNLVPGFFEHLRCLETLKLDNNSISSIPSTISMLKKLRTLSVANNSLSSLPDEIAQLDSLIELDIHSNSIGELPASIWKCSLNSLNATSNLLESFPDPPESNTPQSVPANGVLFSSSSSMTTLCDIDPQTGAQLTSKPLPVPPSITSNTTSSNLANTLETLCLGDNHLPDDVFYALSHFVSLKILNLSHNSITEIPRGQIPNQSHLSELYLSGNQLTSLPADDIERLRSLLVLHIGGNKLTTLPAELGKINHLQVLDVGCNMLKYNISNWPYDWNWNWNLELKYLNMSGNKRLQIKRQTVESLPVATRPGNLSEFGNLTCLRVLGLMDVTITDNVPDDNVDKRVRTSTSTLHNMSYGMADTLGDGENLCIWDLVHEKFQTKDDEVLFGLFDGRPGQSPSSCQLTSRLKDRFADFFKIELEKLEGQDTVVSALRRTFLGLDRELWPLAQSEGGRGGSSALVAYIKGSTLYSANVGDTIAVLVKKSDSYQAISQKHIPWNPMEVSRIKRSGGFVSENGLLNDELDISRSFGQYHLVPIVNSNPYILTTTLTEDDDFLIMASRSFWDVMSYATAVDIAKAGMRIYGDLMYTSQKLRDIAISYGARDHMVVMLVGVGDLFKKKEPLDVAGYHQHKKRPKPTEGPIDALKYLKPEIEPPQGDVAMVFTDIKNSTRLWEDIPIAMAVAIKEHFNIMRRQLRSIGGYEVKNEGDAMMASFSSVPAAILWCFKVQELLVTADWPQDILDSDDGKPVYDPADPSRLIYNGLSVRMGIHWGQPVSHKDEVTRRMDYYGSMVNRAARICASADGGEICVSSDVIKVMQQILADINFEHSDSQDVEHVREMKKLGYWVKDIGEKKLKGLETPESLHLLSTRLLAGRFAVDPKSVAGTPILEAHEQAVQQRMVLDSASVRTLQTICLRLERLVSGAVARHGRATEQSLALLSLTIQDNADQDDLQRIAENCIARIENCFSQLYMAKSGPFVEVLASLSKVLDNDPNYIMRALQTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWX0</accession>
    <name>A0A9P6MWX0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">TFIIS N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008822</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000492">
        <property type="protein sequence ID" value="KAG0016890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWX0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072357">
        <property type="term" value="C:PTW/PP1 phosphatase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008157">
        <property type="term" value="F:protein phosphatase 1 binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.10">
        <property type="entry name" value="Conserved domain common to transcription factors TFIIS, elongin A, CRSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035441">
        <property type="entry name" value="TFIIS/LEDGF_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46557">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 10-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46557:SF1">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="428"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="583"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="78"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="162"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="457"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="482"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="500"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="520"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="604"/>
            <end position="614"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0016890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="745" mass="81339" checksum="56B551B72D9F0D8E" modified="2023-09-13" version="1">MASGQASKGTDLRKGNPTSLSINTTNVRGVKTSIPDLISEEENQVEDDEVEVIRLAQHRPYLQQHQRQPIIENKWRRNSGNTASAGTNTGTSIASIGSESASATSAESQQPTGSAAAHAQAPSTKKALRLHNQRQKAKPEREEREIVTWDRNRRRKARVSDDTSSTSSTPSASPAVSPAPSEGNIDSSDRSLSVSVKMATGPDFSGSDPLSHKVIPSEGIPSTKGKKETAESVAKSDDSTRTRESTPGEGDLGSSSVRYRRYVISPAQKHPQKSSASTSVASGATNNMALPELLRRITPLLRGGSISSASSVDSLVELMSNVNEAGGRKIILNALLSTQSSVILGRFIRSEGLGILRQWIDDARNNSDSPQQQEILQAMIRVLKALPFDAKTLKGSLKGAIALIAGDGDRNHAISKSASDLLQKWGDLSEHTGRSPSRSPHRDKSASARKKSGFGGSQHSLETRQSTAAQKISQLPRFKLRSPTTSSQSQLPSPILASTQKDHPVKEEDTQIRHDLSSAPPNRTTASPSRPTTTINFDPLSSQHNKAMEALRKQQKKSKRVQFKDDAELVSIRYFEKYLGDESANADENEHTKESFDNDDSYSHPEQNSTASIDHQSVTRQFIIPDNEAKRLIDGVAWTPPQLLYIVFEPDPEGRIQEIAHGEQSTEKYWQAERESQVQSVTYRNIFDIPASPEEPDPETEKVLPTDLASQTQIPLFSRDADHVSVLLQTLTGVYQLITRSSGHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MX43</accession>
    <name>A0A9P6MX43_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_009754</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JAAAID010000611">
        <property type="protein sequence ID" value="KAG0015611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MX43"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carboxylesterase type B" evidence="4">
        <location>
            <begin position="6"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0015611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="306" mass="34216" checksum="647CF354158636A5" modified="2023-09-13" version="1">MIEGFGILQGQMDPSRLLTKYLNIPFATIQDKSKQAIKPDPWKGIRDATVLGPMCPQDIQSSNSLTTMMLGLPGPGFEFSERDCLNLNVFAPRFAEHVPVICYIHGGITSGGNALPKNDATNIVKKSIAKDMPVVVVTINYRLLPSAGLLENPDSKSENNETGESVDWGLYDQKLALEWVKKHIHNFGGNPNEITLMGHSSGASSAGYHLLKGQHEGLVKRAIMHSESRHRENEEEDSRVSVPSECDYQQWKPQDQRGLATHRRVEKDNVQFSFMSDACIPYMSNAERQAGFRVVDRWIDFAWGME</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MY63</accession>
    <name>A0A9P6MY63_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glycogen debranching enzyme</fullName>
            <ecNumber evidence="5">2.4.1.25</ecNumber>
            <ecNumber evidence="6">3.2.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Glycogen debrancher</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">BGZ80_007361</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6-glucosidase in glycogen degradation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>Hydrolysis of (1-&gt;6)-alpha-D-glucosidic branch linkages in glycogen phosphorylase limit dextrin.</text>
            <dbReference type="EC" id="3.2.1.33"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Transfers a segment of a (1-&gt;4)-alpha-D-glucan to a new position in an acceptor, which may be glucose or a (1-&gt;4)-alpha-D-glucan.</text>
            <dbReference type="EC" id="2.4.1.25"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the glycogen debranching enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.25" evidence="5"/>
    <dbReference type="EC" id="3.2.1.33" evidence="6"/>
    <dbReference type="EMBL" id="JAAAID010000375">
        <property type="protein sequence ID" value="KAG0018287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004134">
        <property type="term" value="F:4-alpha-glucanotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004135">
        <property type="term" value="F:amylo-alpha-1,6-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005980">
        <property type="term" value="P:glycogen catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11327">
        <property type="entry name" value="AmyAc_Glg_debranch_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000070">
        <property type="entry name" value="GDB1p Glycogen debranching enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.10:FF:000039">
        <property type="entry name" value="Glycogen debranching enzyme Gdb1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000242">
        <property type="entry name" value="Glycogen debranching enzyme Gdb1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010401">
        <property type="entry name" value="AGL/Gdb1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032788">
        <property type="entry name" value="AGL_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029436">
        <property type="entry name" value="AGL_euk_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032792">
        <property type="entry name" value="AGL_glucanoTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032790">
        <property type="entry name" value="GDE_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10569">
        <property type="entry name" value="GLYCOGEN DEBRANCHING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10569:SF2">
        <property type="entry name" value="GLYCOGEN DEBRANCHING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06202">
        <property type="entry name" value="GDE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14701">
        <property type="entry name" value="hDGE_amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14702">
        <property type="entry name" value="hGDE_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14699">
        <property type="entry name" value="hGDE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0320">Glycogen biosynthesis</keyword>
    <keyword evidence="14" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="9" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Eukaryotic glycogen debranching enzyme N-terminal" evidence="18">
        <location>
            <begin position="38"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="Glycogen debranching enzyme glucanotransferase" evidence="19">
        <location>
            <begin position="136"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="domain" description="Glycogen debranching enzyme central" evidence="20">
        <location>
            <begin position="778"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="domain" description="Glycogen debranching enzyme C-terminal" evidence="17">
        <location>
            <begin position="959"/>
            <end position="1420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00020723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00025780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00031477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF06202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF14699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF14701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF14702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAG0018287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1439" mass="164038" checksum="C6B240D5436CB72F" modified="2023-09-13" version="1">MTETVPITIYRVALDDDGSPAENASYIRLPPPNKPYILRFKVITGSLASNQGVVWTNYPPEGKPFKRSEFYQHRLVGVEPESDLMITTSGAYEYYVEHSPYLQDGSIAWSRSKAGYFVVDPQLTLTTHDGSTTTSSIPLEGLVIESMVPKWMGKLSEWKPYLQTVSKSGYNMIHFVPLQYRGISNSPYSIFDQLKFDPRLFEEEDLEKSEEEQRAIVKKVIDEIESSYGALSMTDIVWNHTACNSNWLWDHPESGYNLHNSPHLIPAFELDSALLKFSAKIADPSTAFPSDIKTEEELKVIMTELRRTVFNEIKLWEFYVVDVILSLQEFKAELEARTSYDRNLFDHTSLKQMSLKERGDTLREAALDGLGTHGDRHHKKIKTSVALSFISALLDVDLSNPEGYSAEAVCEEYKTVLNEVNLDFYKSYDKDVDTIVTNIENRVKYMRLDAHGPKLGPISEENPLVETYFTRLPLNERTAKHPPGSLAVVNNGWIWNADPLQDFAGKGSHAYLRREVIIWGDCVKLRYGKGPDDVPWLWERMKEYTIQSARLFHGFRIDNCHSTPIHLAQYLLDAARHVRPNLYVVAELFTGSEDMDIRFVSRLGINSLIREAMQAWDPRELSRLIHRHGIKPVGCMDRSSLCEDVPWTRPDGTTIPSMVTPLNGSRPHALFMDCTHDNETPHQKRRAEDTLPNAALVCMTSCAAGSVKGYDEVYPSLLNLVTESRLYKTYSDPMSVGIISIKAQLNKLHSDMALQGFEEVHVHHENEEPKISLLSDAQGSFTQVEIPDRFPGGSIILIETSVDSKVPSNINDLVKTIPDSVFGNLDWVALNIVLYRCDGEEQDLTQTNDLGHPFCAHLREGHWALDYISDRVKRHLHLFPALKEWHEWLMDRMSAIKKLPNYLVPRYFTLAVMTAYDNARVHAYSLMTPLVRNGDYFTRSLSLTALQVYSFVDSASLHPTEKIPCLAAGLPHFTYRHMRTWGRDVFISLRGILLVTGQYQAAKDHILAFASSLKHGMIPNLLDSLRSPRYNSRDSVWWFFQSVQDYCTIVPNGEDILKESLKRRFPDGHTFVDYTSPEAYSTTVTLEDILAEILVSHANGIHYREWNAGPRLDEQMSDKGFQVDVDLDFKTGFVTGGSIYNCGTWMDKMGESAKAGTKGVPATPRDGADVEIIGLLKSSLRWVIDLHKKNKFRLSEIEIGETRFRGVTRPARKLSIVDWNDLIQQNFEKHFYIPLDPEQDPEYMIYSELVNRRGMYKDTYGSVTPFADYQLRPNFPVAMCVAPELFDKTHAINALTLAKDVLLGPLGMRTLDPNDWAYRPNYDNQNDSDDRMIAKGWNYHQGPEWLWCTGYFFRAYLHFKLQCEPGMVKETVYELHRLMLPHKAQLETSPWAGLAELTNLDGAICLDACQSQAWSSSTLLDLLYDIEKLEVKSAFEIEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYE5</accession>
    <name>A0A9P6MYE5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Post-GPI attachment to proteins factor 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_007164</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in the lipid remodeling steps of GPI-anchor maturation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Endoplasmic reticulum membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the PGAP3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000362">
        <property type="protein sequence ID" value="KAG0018439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYE5"/>
    <dbReference type="OrthoDB" id="419770at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007217">
        <property type="entry name" value="Per1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13148">
        <property type="entry name" value="PER1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13148:SF0">
        <property type="entry name" value="POST-GPI ATTACHMENT TO PROTEINS FACTOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04080">
        <property type="entry name" value="Per1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="2 7" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="171"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="201"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="231"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="259"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="291"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="320"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="9"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0018439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="358" mass="41426" checksum="1A37D6E92CF52668" modified="2023-09-13" version="1">MPHHSLGDTSPASTSTSTSTSTRPSYRRTRFILVLAVVLTLCVSIVLSSSGDRQAEYIDCVKECDKDICQATDFTSLTSEQQQQHELSLPLRLTRWTCLDNCRYLCMQSVTENAIQENQSVHQYHGKWPFYRLLGMQEPASVLFSLLNGYMHVLAWPRLKRAIPEGYYMRPFYLGYAIVGMNTWLWSAVYHSRDWPVTEKLDYFSAGTSIMFGLFYTVIRITRMVNTRSQMIWGIVCLVPLLLHISYLSFVHFDYGYNMAATATIGAIHNLWWICWSFANWRERPYAWEPTILGLLVTVAMCLEILDFAPLWGILDAHSLWHAATIPLAPLWYRFLFKDTEWEVRNKKGVMRSGSHRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYX3</accession>
    <name>A0A9P6MYX3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">K(+)/H(+) antiporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">KHA1_3</name>
        <name evidence="10" type="ORF">BGZ80_006437</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000318">
        <property type="protein sequence ID" value="KAG0019004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYX3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902600">
        <property type="term" value="P:proton transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050794">
        <property type="entry name" value="CPA2_transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32468">
        <property type="entry name" value="CATION/H + ANTIPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32468:SF0">
        <property type="entry name" value="K(+)_H(+) ANTIPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="23"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="117"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="151"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="186"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="216"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="257"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="334"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="399"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="domain" description="Cation/H+ exchanger transmembrane" evidence="9">
        <location>
            <begin position="36"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="863"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="931"/>
            <end position="953"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="938"/>
            <end position="948"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0019004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1045" mass="112346" checksum="17C6AF26503CAE62" modified="2023-09-13" version="1">MSAAAGSVITGLNPTEFNTSNPFVLFVIQSVIIVGLCYLLHFGLHRLKQPRVVSEVIAGIILGPSVMGRVPGFAETIFSPASLPYLNLVSSIGLVFFLFLVGLELDPALVLKRARFALGISFAGMALPLGVGAAVSYVLYEELGPETTVGFGQFLLFCGVAMAITAFPVLARILAEQKLLTTKVGFLTICAGAVGDIVAWILLALVVSIINSASKITPLYVVLLSTAWILVLVFIIRPIFIFMIRYTRSQDEPSQTMMAFTFAVTLISAFLTDIIGVHAIFGSFLVGLIIPNDTGFADGLTKKIEDLVSVVFLPTYFARSGLKTQIGLLDNGRIWGLVILTTTVACFGKIMGCSVAARFQGMEWRESFTIGFLMNCKGLIELIVLNIGYDAGVINDKVFVIMVAMCLITTCMTTPAVTYLYPVHYQRAAALRAGAKRKEEGGDIERAESLGATSRANKGFMICLDKIHNLPAMMTFLEMLHHSVSGAESVSGSDSSLTVRGSNELIVSAVAKEDVVAPKLYALRLLHLTDRSSSVLLAATERAEVLRRDALMTVFQAFAKLNGIFVLPRMTLSTDPDDFAHSIYDEAIESGTGVIVVPWNSSSLPDPPMSSPDGSENPVLSRPLVTSNTRMVSTLLSTTINTGLVTAVFVDREFGGSGHFLNIMVPLYGSKDDEDALKVASAMSHNRLCNIFIVRIEASLRSTKYNENLNVHVDIDAQSIASSVEEVVELPQDNQTLVQRYFPHRAPSLGDRRISNKRVTATGTVEVGSGVFVHAVPTVQDAIGLSKSILSSRDLLVLGRGLTINRAKHSSAASNHAHELPHNPAPVQGTSPGVSVSSTSHGLHLNNLPTGFAFSTANTPTQVIDNPFESDQPITSTPRSRHQLRPQPSSRDLNHSYLTVTTILGVMAQHYLSSGVTSCLLVVQSGGSKSVGAGVSRGTISTTPSASRVPSLHHKQCNNNQCNDREASFDANKQSDYVIPDLDEKRGKHRLSLSPVPIPARARARARARVLVSVPDPDPARAHVFVSAPVSAPIQPQGNSIVLAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZ11</accession>
    <name>A0A9P6MZ11_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PUM-HD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_006184</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000304">
        <property type="protein sequence ID" value="KAG0019189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZ11"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003730">
        <property type="term" value="F:mRNA 3'-UTR binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010608">
        <property type="term" value="P:post-transcriptional regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07920">
        <property type="entry name" value="Pumilio"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033133">
        <property type="entry name" value="PUM-HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033712">
        <property type="entry name" value="Pumilio_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001313">
        <property type="entry name" value="Pumilio_RNA-bd_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12537:SF48">
        <property type="entry name" value="MEIOTIC COILED-COIL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12537">
        <property type="entry name" value="RNA BINDING PROTEIN PUMILIO-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00806">
        <property type="entry name" value="PUF"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22493">
        <property type="entry name" value="PUF_NOP9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00025">
        <property type="entry name" value="Pumilio"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50302">
        <property type="entry name" value="PUM"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50303">
        <property type="entry name" value="PUM_HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PUM-HD" evidence="5">
        <location>
            <begin position="549"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="2">
        <location>
            <begin position="610"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="2">
        <location>
            <begin position="646"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="2">
        <location>
            <begin position="722"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="2">
        <location>
            <begin position="758"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="2">
        <location>
            <begin position="886"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="88"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="283"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="375"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="829"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="947"/>
            <end position="1001"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="227"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="102"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="297"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="375"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="955"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="978"/>
            <end position="1001"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0019189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1001" mass="109100" checksum="A39D1F017B04B045" modified="2023-09-13" version="1">MLGNWYKERLVNAQSNVNSLLLNHSKQSTNASISVQQQPFAEDNEPDVESLFKNSFPTKPANSTIVISINNVNNAITLPPVPIPVLESNSSSRHSFQRHQDQPPQQRVSRSLNPTVILGRLLDPSPELESPLSEPSSIGVPVSNSPGIEEMALMTIGQNGNANTTNLATASSVSLEAVMTIQRAVRRFLVRKQAEINKQPALKLSAPKVVLEINTSTAANNGNKFDIKALQQTCLRQSEEINQLKEIVTKLLLEAEEDRRRLHQKDREIEELVKQQKLSRSSGLDALSSAKAAPRLNNNNNNNNNNALGLSGSTVASSSTTSSFNSFSLQSLAGSRDDSSAGLEHHLTGNALGIPVDDSYEPIVSYSSNIGGPSLHPLSLPSRSNSITSLQSQQPQQSSVHQGLSLKINASQSFYNQQYQGLIEMVDSPSSSEFGSDITTSSGFGAGSRGLAGTHGYGSQSSFPLLSHRSSGSFSSTSRTFDSPTIEQQFAYPWNVPGSLSHSHSWADDMTYGHDSNVPSLDQFQHGGMSCSAGYDPNFINQQYTHGSQQHQGLPQHRKSHRRHSEKSAHLDYQMCVDRILQATDQQASIHLQQKLKTSPPEQKIEIIDTILGQAYPLMSNRFGNFLIQRCFEFGSPQQIEALAQAMRGNILTLACDPFGCHVVQKALDNVEEDCKARIVTEMFRKIRETIVHRYACHVWQKVFEIRWTDAPPAVMTYVNNAVAGRWASVAMDETGSLVVQNIFENCAEHDKRQALNEILQFVTTIAKGQWGNWVIQHILEHGAPADRATVTQKILEHAVSLSLDQYASKVVEKALRTAAIPAHVSTLTGAEKNDGNGNNKSMSDEANGANVGPLTLTVNGTTIRLTQEDVESQYIHIICDGVQDRPRIPLIDIAADQYGNYIVQYILTNAGPQHRETCATLIKRHMVSLRGSKYGQKVAFMVERRRGNPFSGNGNNGNGNGGNSSGQRGVPSYGSKSGSGSGSDGNGGNGGNGGGGRRRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZE1</accession>
    <name>A0A9P6MZE1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005538</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000273">
        <property type="protein sequence ID" value="KAG0019611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZE1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37332:SF1">
        <property type="entry name" value="ELMO DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37332">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="58"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="146"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="217"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0019611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="374" mass="40606" checksum="770A04BF7DA81935" modified="2023-09-13" version="1" fragment="single">MVSRTIEPADADSLYCNPTEDGRSVNSAPSIKSTKSSSSASSSVNSGSRSTKSRSTTRSKSSTSSTPKSPNWKTAMDPMGMSTKSMGSGFMFDTQLYSPGFHAAPKKADTPKSFQNKQLKFVEKRTPPGSSAGSTKSGRSRKSEKSTASSSNKSVKSSSSSSSTKSTFLSSLTGNFSSQGDSAVSLHVKKTEETEPQEMGTPKAESEEATESKKTNDSSNSKNKAAAATDELLVVVEDHSTQGHSSDTLHMPELGNTPRRPSIAESITHLRTPTQRPQHTPNELLLKRVISWEYLGRVHDGKTVYYNAILLTGADLRRFYSPELLQKRTDHYFSLGNSIATALDIPNVSEYARTLSTILHEYEDFISTETKPKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZX2</accession>
    <name>A0A9P6MZX2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006936</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000347">
        <property type="protein sequence ID" value="KAG0018624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZX2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="306"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="473"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="537"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="314"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="341"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="366"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="481"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="495"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0018624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="558" mass="61310" checksum="529F65FAFF73D70A" modified="2023-09-13" version="1">MSRSTTFPSHVQLLMIRHEASLRKQALSTFGPQGVLDLALLGAILGNNIREIGRYKVTCDGNLVQGRYTIYELVHFGALSVTGRCRERQPKAGPFYGERRSSVASNSTAMSVASSGTSNSSRNTLPHIYPTTLANIFPTMVFTALRKKSIRSPKFQHDDSASCTPVSSAFHFENTSAPSTHQEYSETSTASTKDTLSPIDPVLITNEAVLLSLVQQKLHRVKDLPLPRELCFLGAVSLPLPPVLRAMHIAWTIDFLKNRATSARRLRQQLKPTTMTDGNEKPTGGLGFRPDIYAYKMRVARLARAQLQHSRTSSRTEAERHEGVVDSVSMRRGPSSTSIIEENEDEDGNESDDVPSGAAPPRNIPPKTTSSSSETNKLIRQEKRMMQQLLSLENKVPRIVRQWATAARSCFAEELIQEDRQVQEWVDRQRIQVVLACGYRFGSSSATNSSSFSQRRPTLSPISTTLANSLANSGYGGSIHQRASPSPSYTNAKVSPHPLSHPPLSGSRESFPEGVRLGSSPGKAGAIFGVVEKLKAEKRRNDKSLEYQSADVEHASLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZZ5</accession>
    <name>A0A9P6MZZ5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006677</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000330">
        <property type="protein sequence ID" value="KAG0018840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZZ5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0018840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="261" mass="28839" checksum="06950A0FAB868ED5" modified="2023-09-13" version="1" fragment="single">MSRFLGRKSDSRRETTLTHGSGTNHGSGTSHGSGTSHGSGTSHATAHANMLTEGQEHLQKGDNYCDQEDFDNAAKFSKRTAQFYPKEADERRKQIPLQRTMPESNESTSHSSPDQLRVREEGKNQIHTWLTSSSRKPASAGPFFPKNDQPHLSLLKSQATDVPKGSVCAFDDARDTNTIVASFIEADDETKNVLRRQIYDIIIQFKDSLATLETVRELVILARIPDRDVFAQIIEQLLKITKDSSLVPATALQGFAVAVNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0B2</accession>
    <name>A0A9P6N0B2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GLTSCR protein conserved domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_006267</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000309">
        <property type="protein sequence ID" value="KAG0019122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0B2"/>
    <dbReference type="OrthoDB" id="2556847at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015671">
        <property type="entry name" value="GSCR1_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15249">
        <property type="entry name" value="GLTSCR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GLTSCR protein conserved" evidence="3">
        <location>
            <begin position="409"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="110"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="601"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="306"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="117"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="153"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="601"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="620"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="656"/>
            <end position="677"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF15249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0019122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="729" mass="80387" checksum="D302135BD007D74A" modified="2023-09-13" version="1">MATPSTSTGGSAASQTDAESVTHIQMAGLTVLMIKTKDQVIYKLPDNMSVQSLSKEQRERLLAEINLLHHQQTTAQAIAATQAQTQQVQMAQAQAQAQAQQAHGVRPIAPLSINTNGSASASAASTPPASTSLRSSPSAPSTPTGGSASDHKTTRRYNKTGKYSKKKTQSQQESDARGIRSNIAGGTSNGQPYARPPDKSKPQSLVFNNTNPQAYQALAAASQQQQPSTSALTAIPSSILQQQIQQQQASGLSTADQKRQFKLLQEIHQLQQQLEVQQSSINTFREHEKTVQRVLAQNKPVDARTQQLARQNVVDAEKALETLKGQLRDKEASFREQFPIASQQLLLLQQQQLQAASKNGSAPASLSLSAKSPLASNAPKTVEEQLQQQIAEHHDSVRNGMAEAIQTNHKELKRPDYRTPFSSLHDAIGRLLPFHIYQYPPQDIDAQAKAFANRPEVELNARALLIHKRKYDLYNRYHSLIKTSATKPTTTNPSSALDIMALRFGLEDEQEEHKKVSEELELVKIQAKVIQEELERRQIQVLQQRKAEAALIEQQQKLMLERQRQEELEKKQLEQQQEQMVAQIRQMQELQQMQRLEEMQEMQLHLQQQQESQLTEEQEEARRKEEVRKELERQHQLELEKQMRIKQEQMSKEAESAQNAAAAAAAAVAALRAVATATPPVSGTETLGAPGSSGSGTVIPSSTSTPVAAVITSTTASTVTPTPNSPSTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0I8</accession>
    <name>A0A9P6N0I8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">aldehyde dehydrogenase (NAD(+))</fullName>
            <ecNumber evidence="5">1.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ALDH7A1</name>
        <name evidence="9" type="ORF">BGZ80_005909</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.3" evidence="5"/>
    <dbReference type="EMBL" id="JAAAID010000291">
        <property type="protein sequence ID" value="KAG0019377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0I8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07130">
        <property type="entry name" value="ALDH_F7_AASADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000018">
        <property type="entry name" value="Alpha-aminoadipic semialdehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044638">
        <property type="entry name" value="ALDH7A1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43521">
        <property type="entry name" value="ALPHA-AMINOADIPIC SEMIALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43521:SF1">
        <property type="entry name" value="ALPHA-AMINOADIPIC SEMIALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="3 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="8">
        <location>
            <begin position="72"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0019377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="544" mass="58610" checksum="6A809CA45E51C6F4" modified="2023-09-13" version="1">MTSMLLNRLSQNRTTLLRSVASRTAIRSMTILNYSSSSKISPKHKAIFDQLDLQFDNKGVFNGSWGGSGPIVESVSPADGSVIGRVQTGTVQELNETLEKMEKVKVMWRETPAPKRGEIVRQMRDALNEKLEPLGALVSLEMGKILPEGKGEVQEYIDICDFALGLSRTLNGQVVPSERPGHFMIEQWNPIGTVGVISAFNFPVAVYGWNSAISLVCGNPVVWKGAPTTNLSSIAVTKILEKVLVKNGLPGELCSLVAGGADVGQSMVEDDRVKLLSFTGSTAVGRKVGETVAKRFGKSLLELGGNNAIVVMDDADLDLALRSVLFAAVGTAGQRCTTTRRLLLHEKIHDEFLEKLVKAYKSIRIGDPLEAGTLCGPLHTKAAVEHYRKGIEAVKAQGGKILTGGEVLDRPGNFVVPTITSISPDADVVQNEIFVPILHTMKVKNLEHAIEINNSVKQGLSSSLFTRNPEHLFKWVGPSGSDCGIANVNLPSSGAEIGCAFGGEKETGGGRESGSDAWKQYMRRSTCVINYTGQLPLAQGIKFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1C6</accession>
    <name>A0A9P6N1C6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Patatin-like phospholipase domain-containing protein</fullName>
            <ecNumber evidence="6">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_004450</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Lipid hydrolase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Membrane</location>
            <topology evidence="6">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the PLPL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="6"/>
    <dbReference type="EMBL" id="JAAAID010000227">
        <property type="protein sequence ID" value="KAG0020288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1C6"/>
    <dbReference type="OrthoDB" id="15478at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006641">
        <property type="term" value="P:triglyceride metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07232">
        <property type="entry name" value="Pat_PLPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050301">
        <property type="entry name" value="NTE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021771">
        <property type="entry name" value="Triacylglycerol_lipase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226">
        <property type="entry name" value="NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226:SF66">
        <property type="entry name" value="TRIACYLGLYCEROL LIPASE PTL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11815">
        <property type="entry name" value="DUF3336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5 6" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="4 5 6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="127"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="PNPLA" evidence="8">
        <location>
            <begin position="310"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="732"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="5">
        <location>
            <begin position="341"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="12"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="40"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="740"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="343"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0020288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="763" mass="87065" checksum="89FAE15BCEDB1385" modified="2023-09-13" version="1">MALPNNPGSNGRSRKTTPPRKKAQANPTTQTHFPHHDQQSYESSHSDFSYDSSRTVSPTHEPYDRIPEFDQTYVNEDHIHAFRQALEDSVHSDTSAELISAVTDFMPVQQTPLKRTRGRKSPKRYNGYSYTLLRIPLLIFIFSIMAIEMFIYVSVRQIVNFWEYFVTWRGRRNRLRKDLRNASNYGEWKAAAQRLDTYMKKDEWKNDPDFGYYDYHLLSRVNRNLHLARESNRIDELKDHLQGVVKSNFGGVENARLYSHTYHGTKQPVENYVQEVTASLQAVTESGQLTDDEKRIFLKSIYKNFGRTALCLSGGAGFGYYHLGVVRALLDAGILPTVITGTSAGALIAALVGCRTDDELNEVLVPEIAHKFTACNENIFTWLPRVIRKGARFDAEDWARKSQWITKGSLTFLEAYERTGRILNISVIPYDPHSPPKLLNYLTTPDCVIWSAVIASAAIPGILNPVVLMRKRPDGTLVPFSYGGRGFKDGSLRADIPLQALHTHFNVNYTIVSQVNPHVHLFFYAARGSVGRPVSHLYGEGWRGGFLAASIEQFLKLDLSKWLKVLRDLELLPKIMNQDWSWVWLQKFDGHVTILPKSGLSDWFQLLADPDETRLRHCLTVGERQTFPKLHMIANRMRIEQMIAACRSEVKEKLDRKSHGRGVRIGMSRLLSEDSENTVKARMQSFGDSFAQKGFAGDNPIMASEGKRRKKRASWPNLRYALGRESVGDYGSLKAQGLLGDDEDSYMEDEYEYERDDNPMFSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1C9</accession>
    <name>A0A9P6N1C9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">LSM complex subunit LSM3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">LSM3B</name>
        <name evidence="9" type="synonym">LSM3</name>
        <name evidence="11" type="ORF">BGZ80_004581</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Binds specifically to the 3'-terminal U-tract of U6 snRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">LSm subunits form a heteromer with a doughnut shape.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000232">
        <property type="protein sequence ID" value="KAG0020220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1C9"/>
    <dbReference type="OrthoDB" id="29543at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120115">
        <property type="term" value="C:Lsm2-8 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005688">
        <property type="term" value="C:U6 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01730">
        <property type="entry name" value="LSm3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000007">
        <property type="entry name" value="U6 snRNA-associated Sm-like protein LSm3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034105">
        <property type="entry name" value="Lsm3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040002">
        <property type="entry name" value="Sm-like_LSM3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13110">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 9" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 9" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="10">
        <location>
            <begin position="14"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0020220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="99" mass="11257" checksum="B317F981B085FFA9" modified="2023-09-13" version="1">MDDHAPLESTGIEEPLDLVRLSLDERIYVKLRGDRELRGRLHAYDGHLNMVLGDVEETITVVDVNEETMEEVIRIVKRNCEMLFVRGDGVILVSPPSRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1E1</accession>
    <name>A0A9P6N1E1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_002611</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Peroxisome membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000165">
        <property type="protein sequence ID" value="KAG0021336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1E1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016559">
        <property type="term" value="P:peroxisome fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008733">
        <property type="entry name" value="PEX11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12652">
        <property type="entry name" value="PEROXISOMAL BIOGENESIS FACTOR 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12652:SF19">
        <property type="entry name" value="PEROXISOMAL BIOGENESIS FACTOR 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05648">
        <property type="entry name" value="PEX11"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="1" id="KW-0962">Peroxisome biogenesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="198"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="81"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="96"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="132"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00046271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0021336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="515" mass="56186" checksum="4F2C8F9180AA69A0" modified="2023-09-13" version="1">MTHSSSSSSSPSPSSPSTVTPAAAILHSQQQQPQPHHMHPWPTERAKIAAESEISPPISPKQHAVVGGPQGDDFLEPLQETNNSSSHDTTNNNSHSRSHSYSHTHSRKSSLYHQRPLSGTIGLNSPPLEPMSTGLLLTRSDSSTSSSGSVSSSSSSTSLSSHSSVSPSSSTLQSYSSSSTLQKLDVERKLTELYLINTPPSSHVTSPSSPPFPALKEPLPLDSAGDLSLLNNASSITASAVTTARPKTRAPYHCTKKSLPQIIREISDLVDGRDKAIKVVQYFAKVFLWLFLSNPKQYQILATRLKALAKQFSTTRKVLRLAHFIDPLASVLTLAVALRATLQKHGLRGTLAKSPSQTWRDTTRDRLGSLNTLIGFVQDIADDIYCLGVIGVLDRSFSDKAEPWSNRLWMMGVTIDLHENYQSIRDVKEHIRALELKAIEGHKSEEEEKAWTAQHVKLTTKLHWLKVTTVKLGGDFLFCAYDNLHCSFSDGFQAVTGFVSGVAGAYKFVGKVMES</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1X8</accession>
    <name>A0A9P6N1X8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Inhibitor I9 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_002178</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protease inhibitor I9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000153">
        <property type="protein sequence ID" value="KAG0021544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1X8"/>
    <dbReference type="OrthoDB" id="5518345at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004866">
        <property type="term" value="F:endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042144">
        <property type="term" value="P:vacuole fusion, non-autophagic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.80">
        <property type="entry name" value="Peptidase S8 propeptide/proteinase inhibitor I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052471">
        <property type="entry name" value="PBI_I9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010259">
        <property type="entry name" value="S8pro/Inhibitor_I9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037045">
        <property type="entry name" value="S8pro/Inhibitor_I9_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28288">
        <property type="entry name" value="PROTEASE B INHIBITOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28288:SF2">
        <property type="entry name" value="PROTEASE B INHIBITOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05922">
        <property type="entry name" value="Inhibitor_I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54897">
        <property type="entry name" value="Protease propeptides/inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040132033" description="Inhibitor I9 domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="Inhibitor I9" evidence="3">
        <location>
            <begin position="28"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0021544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="98" mass="10439" checksum="639161A7603C8AD7" modified="2023-09-13" version="1">MKFATIVALLVSAVAVSGAAIPQEESQSYIVVFKSTTTAEAIEQVEKDIVGFGGKIGQHYDTVLKGFSAWIPTQVVSTLSASPFIAYIEEDAKVTTQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-10-08" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1Z7</accession>
    <name>A0A9P6N1Z7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RWD domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RWDD1</name>
        <name evidence="4" type="ORF">BGZ80_002075</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000150">
        <property type="protein sequence ID" value="KAG0021608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033554">
        <property type="term" value="P:cellular response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009893">
        <property type="term" value="P:positive regulation of metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051246">
        <property type="term" value="P:regulation of protein metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd23823">
        <property type="entry name" value="RWD_GCN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000050">
        <property type="entry name" value="eIF-2-alpha kinase GCN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040213">
        <property type="entry name" value="GIR2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006575">
        <property type="entry name" value="RWD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12292">
        <property type="entry name" value="RWD DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05773">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00591">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50908">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RWD" evidence="3">
        <location>
            <begin position="1075"/>
            <end position="1180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="180"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="372"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="417"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="565"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="633"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="772"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1232"/>
            <end position="1255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1281"/>
            <end position="1305"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1023"/>
            <end position="1071"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1174"/>
            <end position="1208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="207"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="232"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="642"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="774"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1232"/>
            <end position="1245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1286"/>
            <end position="1295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1296"/>
            <end position="1305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0021608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1305" mass="145347" checksum="BF15794006321718" modified="2023-09-13" version="1">MRPEDWLGALTADQSPSTQPAPGSKTVLVCYHDVSLEVMGDDLGKDCSEIDLEPDLCPRFHQLNNVPAEQGTRALSGATPYIFNTTPTTTILPFPNPSIDSHSITTPGGISLRYMSLAAVTGDYPNLAKNDRIFSNPNFNPIKSIMLGRLKEQEREQQGLIQFQQSQLYIPGEVLKEGRQAQMSPKAGGNGQRSERRQAVNTGIRCSGSTSSSSTSSLIEDPEPTRTKGKKTTVSSPKPVVESTTIHTHYSQSQTYSNKAITQERSPNVEQWDAGPSPKAAGRSELYRKSEPRDSLVTTIAVDQSRSCGIQAQRPTFLSVPLIYRPEAILLYPQPPCLEQVYPQSQPYPSIVPNVAAPRPIPAMQASYILGSTSSTSSPSDPYSSSSYSSSSSPTVYHVANVRHVALLETPRGIHQPTLKERNHQPGFAHTKGKGDDGAGIHHSTCNDTKGIRTVEGLDPAKVRMLNHLRSMDFLKRAKHPKWDGERRKSYDSKIEFHRVVSTRRRARTLTDHMESVTLEQQSRRNSHNPAHNGVGLPAVHDESHQERVATLASQTVLATLFKAHSSQKNDTSESKKIPSPLYELNSRRKSLGDNKLTTNSVLHIPVPYLKEQEYSRCVRETLGLLLSSQTSSEGITQCPNGSPSASGSSAGLFPSSTSVHPDGSLADQKTKVQQFIHILAVLSKISAKSHYFYWMPPYCDLNMDGIDLNSVESSHSDPNNRMWAEGSEIQLMMAAGKAAVDARKSSPYTNRNKVKVPSVAEWMLRERKDSGYTTLSSSPTTPSSSTFPSPLSQSHNPTTMGGCDDSTMTLRQALVVMEKKKTNSTFDILAFAKAYNTAHDTLVQSPVASTVDDPWDEDDFEVADSLEHGDSFNSEQYSSSYMTGSYSPSIGYSDLRDWVSESEKSVMSSSTIQLATPPMRGSPWSSSMSVYGDTPPYSPVSQHSVGFIPGANNSDSSLDDTYVFVTCDHCMQELYLEGAASSTLDAHQHLNCVKLVRKKIQGWYSRMKVFFGIGVAGRLKRIEAEKRKQKKYRLKMMELNKKMDLAMAQMIQLQEEHERFLRAIDEHYKEEQANELEALQSIYPDEYEEISRDPGEFTILIVPDEQDGEDTYSLKLHVKYTETYPDALPEFSIDMEEGELGQEDFDTIMKKVTEAAEEAIGMGMVFSMASIAKDSLTEIIQINKIRREELERERELREIEEEEKRKAGTKVTTEVFLKWKTAFDAEMAEKERIEKGGKREDPKMLKPTGRQLFERDHSLAKSDATFMEEGDVDVDVSLFEREENISDDDDDNENDVLRNIRSSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2B1</accession>
    <name>A0A9P6N2B1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_003243</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000185">
        <property type="protein sequence ID" value="KAG0020988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N2B1"/>
    <dbReference type="OrthoDB" id="655030at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050562">
        <property type="entry name" value="FAD_mOase_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356:SF2">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356">
        <property type="entry name" value="FAD-DEPENDENT MONOOXYGENASE ASQG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="7">
        <location>
            <begin position="7"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="7">
        <location>
            <begin position="277"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="451"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0020988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="510" mass="56175" checksum="EBA06FE73DD918B0" modified="2023-09-13" version="1">MPSGSSTKVIIAGGGLGGLVLAILLQRAGIDYFILEQSVIIRPLGTVVVISAMVSPLMEQLGLLDEIESHSKPFGGITFLQDDHSFVGKIVLNNKKAIDQKERYGYYDQCIPRPDLYNIFLSRIPKERLKLGKRLVSFQNVHSSNDGENVNLYSTLSSPSERVMVRCSDGTYYYGDVLVGADGASSSVRQSLFRQMKEEGTLPKVDQEEQQFRQSWFMPVSGDRYSWLVTRTLEKPITINSGNSNLSEWGPVATGPGEATVGDLIDNTERHLIYKVMLEERTFRTWHGGRTVLIGDACHKSVPFMGKGAGESMLDAVVLASLLYDMPSSPTDPSTPSFKDYDALQDVFRQYYLTRADAAKEAVGVSSLFASLLVKEGWVGHVMRKAFFGLTTGRMARSKLDKFGYQKIQASFLPQVRHQGSSPCRPHVVSKRPVIGAGYYYTDDEIDDENYTISTEGKDGSNAEGDAEGTRSIGGSSLGRLKGIAEDQVFDHAVVDEFLTGVRPPNPVFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2J4</accession>
    <name>A0A9P6N2J4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_010998</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000083">
        <property type="protein sequence ID" value="KAG0022847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N2J4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="127"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0022847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="212" mass="23391" checksum="5F7E342898420CF3" modified="2023-09-13" version="1">MASSFEQDQQLFADTILKLQIHSALAKENIKNKKSPVPLLAQSCSLLDNFPTRSQHWTPAQETLINSLKIDSWLALTDACIQANDLIQAESSLHRLSALQEAAAGPLSLRSKANKSSRNKSRDTGRSSNNTSATVATTIPETAHVSDNPPSATSNPSYAEATTEQRQAANDLIQTWEKLSQVYSDMGKQDMANNFAKRSEKMREHLKNQQPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2L2</accession>
    <name>A0A9P6N2L2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Acyl-CoA dehydrogenase NM domain-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_000572</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000112">
        <property type="protein sequence ID" value="KAG0022302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N2L2"/>
    <dbReference type="OrthoDB" id="434771at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033539">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA dehydrogenase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.110.10:FF:000002">
        <property type="entry name" value="Acyl-CoA dehydrogenase fadE12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050741">
        <property type="entry name" value="Acyl-CoA_dehydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48083:SF13">
        <property type="entry name" value="ACYL-COA DEHYDROGENASE FAMILY MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48083">
        <property type="entry name" value="MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0274">FAD</keyword>
    <keyword evidence="4 7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase N-terminal" evidence="10">
        <location>
            <begin position="12"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="9">
        <location>
            <begin position="138"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase C-terminal" evidence="8">
        <location>
            <begin position="252"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0022302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="432" mass="47514" checksum="71A81F8F45849DCC" modified="2023-09-13" version="1">MASIFELSPRCQEMQRKLVDFVENDCIPAEDIYESQVGKGDMRWKVVPPIIEELKAKARSLGLWNLFLHKGYPEGPGLTNLEYATLCEITGRCPRVAPEALNCSAPDTGNMEVFAKYGTPEQKQKYLVPLMNGKIRSAFAMTEIAVSSSDATNIETRIERVGDHYIINGHKWWISGAGDPRCKVYLVMGKSDPNNESQYKQQSIVIVDAGTPGVEVVRPMTVYGYDDAPEGHCEVKFTNVKVPVSNIIAGEGRGFEVIQGRLGPGRIHHCMRAIGMAERTLDLMIARVTDPSRRTFGHVLARHGTVAADVAKIRIEINAARLLVLAAADKIDKVNAKGALRDIAMAKVMVPNMLQRTIDLATQAFGAAGLSQDFPLARFHAGARALRIADGPDEVHIQQLARFELFRGDAIRGKQEAAKARKAQILANNSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2P9</accession>
    <name>A0A9P6N2P9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_002534</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000163">
        <property type="protein sequence ID" value="KAG0021369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N2P9"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24296">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="450"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0021369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="508" mass="58102" checksum="BE8FC3311385209E" modified="2023-09-13" version="1">MTSSAVLRLLTRGNASKLFLAYVLYIVFKYRRSVYGIRPRPEIKGPRGLPLIGNTLEMIAVPQTRILEEHERLRALYGRVYTYAMPKVGRIIYLHDPEIIDHVLRTNFWAYGKGQRAKEVAMPLTGNGIFTADGDHWKWQRKLASNIFSVKAFRQYTSDVFCREGDLAIEYLNKIADTGKPVDIQQLFYCYTLDSFGEIAFGVSFGSMKDPEQEVDFAAAFDRLTHGVAGRVYSPIWWLTDWWTGNGKQVEKDSKLVRDFALRVIQERRNKEHAPAQEKDLLQLFMDLTDDDGQPLSDDMLIDSVLNFIIAGRDTTAQSLAWMFYLMHRNGSNPEFVQGLIKETDEILKGGYPTYESTKQQKYAEACFHETSRLYPSVPRSTRICFEDDVLPGGIKIYKGERIGWSTWVMGRDTTIWGPDAKEFNPNRWLNNDKPSSSKFLSFHHGPRTCLGQQYATIEAITITSMLFQKFTFELVDPNVKPTYYPSPTLPIAGGLSVLVKRRTDIAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3C8</accession>
    <name>A0A9P6N3C8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Homoserine O- acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">MET2_2</name>
        <name evidence="6" type="ORF">BGZ80_009669</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. MetX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000060">
        <property type="protein sequence ID" value="KAG0023357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3C8"/>
    <dbReference type="OrthoDB" id="191364at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004414">
        <property type="term" value="F:homoserine O-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009092">
        <property type="term" value="P:homoserine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00296">
        <property type="entry name" value="MetX_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008220">
        <property type="entry name" value="HAT_MetX-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01392">
        <property type="entry name" value="homoserO_Ac_trn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32268">
        <property type="entry name" value="HOMOSERINE O-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32268:SF11">
        <property type="entry name" value="HOMOSERINE O-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000443">
        <property type="entry name" value="Homoser_Ac_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="5">
        <location>
            <begin position="88"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="277"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="286"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="308"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="158"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="399"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000443-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0023357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="477" mass="53415" checksum="F14CCCA74008AD6D" modified="2023-09-13" version="1">MPFERRTTQPENPFSRLSPGQTIVIVPEFKLDSGYTIRDVPVAYKTWGVLNEAGDNCMLICHPLTRSVDVEDWWANLMGICGLEGKGKAIDESKFYIVCLNVMGSPYGSASPLTMNPETGTRYGPEFPQATIRDDCRLHKIVLDDLGVKSVAICIGGSMAGMHVYEWAFYGKDYIKLLVPISAPAKSSAWSMSWTESQRQSIFADPKYLDGYYSLDAQPTQGMIAARMTAMLTYRTRASYERRFGREIMDSDNSSQQEKPSIPHSEVHRLAHNAGHRHMKPYPLSFPSTNSSAASLQTPDQSHSSKESVASTNGSSSPSTPDSSSQQETKIAAYQPPMYSAHSYLRYQADKFNERFDANCYIALSRKMDGHDVLYGRGNYEDVVRSIQQPTLVLGIESDVLYPFYEIKALSELLPNAELICVKSEEGHDGLLLEYEQVNDAIVAFMQKHEHIREILRQKGVPIPERNGPRGAMFASW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3I7</accession>
    <name>A0A9P6N3I7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Histidinol-phosphatase</fullName>
            <shortName evidence="8">HolPase</shortName>
            <ecNumber evidence="3 8">3.1.3.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">HIS2</name>
        <name evidence="11" type="ORF">BGZ80_007571</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>L-histidinol phosphate + H2O = L-histidinol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14465"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57699"/>
            <dbReference type="ChEBI" id="CHEBI:57980"/>
            <dbReference type="EC" id="3.1.3.15"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 8/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the PHP hydrolase family. HisK subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.15" evidence="3 8"/>
    <dbReference type="EMBL" id="JAAAID010000039">
        <property type="protein sequence ID" value="KAG0023879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3I7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004401">
        <property type="term" value="F:histidinol-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:L-histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12110">
        <property type="entry name" value="PHP_HisPPase_Hisj_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010140">
        <property type="entry name" value="Histidinol_P_phosphatase_HisJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004013">
        <property type="entry name" value="PHP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016195">
        <property type="entry name" value="Pol/histidinol_Pase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01856">
        <property type="entry name" value="hisJ_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21039">
        <property type="entry name" value="HISTIDINOL PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21039:SF0">
        <property type="entry name" value="HISTIDINOL-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02811">
        <property type="entry name" value="PHP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89550">
        <property type="entry name" value="PHP domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PHP" evidence="10">
        <location>
            <begin position="4"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="218"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0023879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="318" mass="36568" checksum="0094A860E025B294" modified="2023-09-13" version="1">MFSFHSHSGQFCMHAKGTLEQVVESAIQRQFTTYGLSEHMPRYKVEQLYPEESHLMTQDLERMYDQFLQEAARLQQKYAEKIHLLIGLETEYFGPESTQYVRTLRQPHRRTIWTANHSSTSGIEAGAMDATLSSSPQVALPQVQYIVGSLHHIHGIPLDFSQELYLKALEDVGHGSWETLFREYFNAQFEMLQGLEPEVVGHLDLVRIFFSAIKGHHHHHHHNGQEQDEDEGEQEQGTGQNKLTEELWTLVKRNVDFVIGYGGLFELNSRAWKKGLADAYPQRDILQYILSKGGRVTLSDDSHGPDDVGMFYNPELKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N5C9</accession>
    <name>A0A9P6N5C9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_005479</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000027">
        <property type="protein sequence ID" value="KAG0024173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N5C9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0024173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="69" mass="7905" checksum="CACCF298704844D3" modified="2023-09-13" version="1">MNEVFLFDVHEPFQLEMTIRGKPVPKKFGTMAGFSNSQTAVHGQLDLSFCPESMEKSVRTYKLHRSVED</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N5Z7</accession>
    <name>A0A9P6N5Z7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">COP9 signalosome complex subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_005694</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CSN3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000028">
        <property type="protein sequence ID" value="KAG0024147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N5Z7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008180">
        <property type="term" value="C:COP9 signalosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055089">
        <property type="entry name" value="COP9_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050756">
        <property type="entry name" value="CSN3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10758">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 3/COP9 SIGNALOSOME COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10758:SF1">
        <property type="entry name" value="COP9 SIGNALOSOME COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22788">
        <property type="entry name" value="COP9_hel_rpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0736">Signalosome</keyword>
    <feature type="domain" description="PCI" evidence="9">
        <location>
            <begin position="200"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="413"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="431"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="458"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0024147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="480" mass="53436" checksum="39217F4EC474A8B2" modified="2023-09-13" version="1">MAGEPSFDEIISKIQSCSDPTSIAKTLASFLNNLNENVFSARPHGQIDPLDTLSPAIHSFAYLYFLVYRCKASHGFHPALLEKVWAFVTTCDGEQVRLASDKALSFAEALVKMATESFQPIIAIRPLAVFIRRLQASPGQLTMIHPLLAKTCLLAQSFKDIIPIIDNDISDVDPQHTKINYKDFLLYHYYGGMIYAYLKKFDRAVEFFKLAVSAPAEVASAIQIEAYKKYVLTSLLHYGKVPVLPKYTANPVQRCLKAHCGPYAEFASAYEKKTNNVIKTELEKIKPILIRDKNYGLAKQCMEALHRRNIQDLTRTYLTLSIEDITSLIGLGSEPEGASRVEGIIVKMIESGAIFATISHEHAGGMVSFLDDPNQHNSTTTTDMINAQIQKATVITSSLVAMDQTISSMPAYFNKKASSNKPKRQRLTSGSHERNTHRGRGDEGETAGQVNPEEELDADLKESRQAENEQPEKLDDLSEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N7D8</accession>
    <name>A0A9P6N7D8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_011334</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000009">
        <property type="protein sequence ID" value="KAG0024666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N7D8"/>
    <dbReference type="OrthoDB" id="2435805at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051694">
        <property type="entry name" value="Immunoregulatory_rcpt-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549:SF26">
        <property type="entry name" value="AXIAL BUDDING PATTERN PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549">
        <property type="entry name" value="PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040441781" evidence="7">
        <location>
            <begin position="19"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="177"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="147"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="265"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="347"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="147"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="360"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="383"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0024666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="458" mass="47692" checksum="83AD0816F9B9AE38" modified="2023-09-13" version="1">MVLAFFIVFLSLLSGVSASITCALPAGSTYKAGDPIILDWGSDGTSPVVSDITSINATLYCNGNNVQIAYVSIPNLTGPYNWTVPSVGNATTVGGTVGTCPLNAFHIEYAGEASGFLGIVKIPWGPARCGTITITPAPNGTVTITTTTTTTSSTTSSTTSATVSPTQSADNSGGNGLSMTAVVIIAVVAAVLGTLAVVGIVACIRKQRRQRKLDDAFMPWASGAATRFSKVSSTDEDQGPDTVGMAAAGAGAGIGASAVGRVSYEMKPQPTSPSGGAYYPNEGDYNNYGYQQQQQLLQRQRQLDYRNQGYESYNEGDSYYNPYYASGVSGASGVMNQSNPSFYNMNNSSALGNRVRPPYAQNSDFNQQQHASGYIPPPPPGPLNSSPLSYGGTGTGLTSSETVPSALTSLPTSSSDTSSPKRAPQTVMQEMGRKEAEEGTNQDFIPPNSPTTKVEVTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SQ72</accession>
    <name>A0A9P6SQ72_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_009161</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010005266">
        <property type="protein sequence ID" value="KAF9991385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SQ72"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9991385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="148" mass="17063" checksum="AFA00C76F1DC2D9A" modified="2023-09-13" version="1" fragment="single">TTAPSSQQLKPTGAYNSKIGIIGMQNLDHMHSPNNEMEDEQMEYEWIDVQRNRDRYLAATVPQDLIYGDTKEKRKEELRRLLVTHKIHCTEGPSDAKSATGEKIFRVAVESQKDLDVLLSLTVEDSNEEERTSVFYKMFTRLDNARQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SRS4</accession>
    <name>A0A9P6SRS4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007865</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004108">
        <property type="protein sequence ID" value="KAF9994286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SRS4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="312"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="374"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="391"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9994286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="420" mass="46079" checksum="CD10FB6E97EA01F9" modified="2023-09-13" version="1" fragment="single">TYPRGNCDEHENPARPEKVFDIMELRNSTLECHLRPSAQPKLDRHIADLLFPIAAVEPVLSRIDREINLATSHASTVSSRSEHRHKPSKSVILKAPKVDLTLLPEEQAGYPRGDINRQENPHRLANISDVVEVNYPQMGFSTPAKMAMQPIIAPTEAISPLILDSGARLASIPSALPRKDTTRLRTSRKRPVSSSTLAAATPRELKRSRSTAVTLKRPRINLFLYPEEQPDYPRANVMRRRAKRPLRIPEPAKAVASEIQLDPEHQHPHHDLHPTIVESATAAVTHGLEGIMSLLGSIHLPNVLLQGDVATGTDDVANSEPRSPHHHTPQTSISGPIYQSSFAARARDIPLVPVSEPLINIDQEPAGRPIQVAGKMPSRKLSLPVPKVSESDSSTSSTRQVTTAESSHGSLFAPFEKAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6STC1</accession>
    <name>A0A9P6STC1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_006681</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003303">
        <property type="protein sequence ID" value="KAF9998963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6STC1"/>
    <dbReference type="OrthoDB" id="439808at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236:SF51">
        <property type="entry name" value="NUCLEOLAR PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="115"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="205"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="25"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="60"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="81"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9998963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="253" mass="27872" checksum="456E82C7826465CF" modified="2023-09-13" version="1">MVEKITKKQKKASEFRNKKKKLDDSIADVPEEDTPETTEEKDTESKAKTSLKRKERDTETTATDAGSTADGKKKRRRGKGSTKDQAAKEGVEETEKEANTDKAVKAPPKNQKFIVFVGKISSVRVQTDKVTKKGKGFAFMEFPDVESMQKALFFNKTLIKERPINVELTAGGGGNKSAARKQKIAEKNEALNEERRKLHEKHIAPAKEAKSSYAAANPPVVQKAAPKNIKKPHEISGANSISVDGLAARLRKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6STR0</accession>
    <name>A0A9P6STR0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribosomal protein S15</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RPS15_1</name>
        <name evidence="4" type="ORF">BGZ80_006180</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003037">
        <property type="protein sequence ID" value="KAG0001442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6STR0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000028">
        <property type="term" value="P:ribosomal small subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.860.10:FF:000002">
        <property type="entry name" value="40S ribosomal protein S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.860.10">
        <property type="entry name" value="30s Ribosomal Protein S19, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002222">
        <property type="entry name" value="Ribosomal_uS19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023575">
        <property type="entry name" value="Ribosomal_uS19_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11880">
        <property type="entry name" value="RIBOSOMAL PROTEIN S19P FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11880:SF2">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00203">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54570">
        <property type="entry name" value="Ribosomal protein S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0001442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="129" mass="14951" checksum="578644C18A72514A" modified="2023-09-13" version="1" fragment="single">MTWWTKDNSTNPTTYRSIIADEHHDDAAVDVKKKRTFRKFSYRGIDLDKLLDLSSEQLMDLVNARPRRRFQRGLKRKPMGLIKKLRQAKKDAPALEKPAVVKTHLRNMIVVPEMIGSIVGVYNGKTFNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6STS6</accession>
    <name>A0A9P6STS6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Endoribonuclease Dicer</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">DICER1_2</name>
        <name evidence="4" type="ORF">BGZ80_006154</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003023">
        <property type="protein sequence ID" value="KAG0001605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6STS6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004525">
        <property type="term" value="F:ribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00593">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1520.10">
        <property type="entry name" value="Ribonuclease III domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000999">
        <property type="entry name" value="RNase_III_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036389">
        <property type="entry name" value="RNase_III_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14950">
        <property type="entry name" value="DICER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14950:SF37">
        <property type="entry name" value="ENDORIBONUCLEASE DICER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00636">
        <property type="entry name" value="Ribonuclease_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00535">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69065">
        <property type="entry name" value="RNase III domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00517">
        <property type="entry name" value="RNASE_3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50142">
        <property type="entry name" value="RNASE_3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase III" evidence="3">
        <location>
            <begin position="243"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0001605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="377" mass="42079" checksum="CCF1CAD066BE8179" modified="2023-09-13" version="1">MKRQADQDTISPNTRHPRLSPDQDDTLAEDTIIIDEGEIWEQRKKAILKLGTRSPDLYVCFLSAISLVRRHFSETDDVKTKTGLKFKGVFDSDSEKWECHLSHPSSTTTFESGPFARQDHAICWVAFVACRELRLDFPSIGLTMEGQPANAEGKLTQRISDRLSVNRILSCADDLAVRTFLCRSSPPASRVMQFVKTTVACAYYRGGFYLALAVASGVIGPMEGIDAWGDFALPGAVKGRFTYERLEFLGDAVLDILAAFYFLGRNQQISEGDLCKDVSDSTNNAALGALCLESKYYGHSRHRGLEKHIIDGEQAFLTKKRQACYWTRLLIPKVCFANIIESAFRAVFLDSGFDLEAVGYVFDKIACPFLDSDFPCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6STU9</accession>
    <name>A0A9P6STU9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_006111</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003002">
        <property type="protein sequence ID" value="KAG0001826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6STU9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0001826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="57" mass="6287" checksum="F874582830277F4D" modified="2023-09-13" version="1" fragment="single">NKAKDVDGDENKLHEISVVIIVVDEFFADGTDIDGQTCKEDDDDEGIAGWVLKEDYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SUE5</accession>
    <name>A0A9P6SUE5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005707</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002804">
        <property type="protein sequence ID" value="KAG0003980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SUE5"/>
    <dbReference type="OrthoDB" id="48988at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0003980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="334" mass="37641" checksum="B429B094B82F43C3" modified="2023-09-13" version="1">MASHAFEKVQGSSKKEKEPDPSTDNVDPMASSLVNNGSSCPSKPYQRKSHGLGFFQMPGNLLEMEGVQTTANWAKRQGLRVFLNRPLNAMLSDRHPVRLASYSRPQSPSYAEAKDQILETLSATEQWDGRLQPGMSRLREMIESLDASLRVGAISTMHLEGPSIMNLLRQELTVPDSVKSSPQQHPYTSLTSAQQQAISHENSFGDGPHNGPLHRRSRYSHYSHAISQIHNDMKGSSTAQCTLLKTSVFEVDKLVKCLDQYVQIFHQQVRFQESSRVEKMLTDRGIDLRGETVEKFALEHLLEHEQIDSMLLGMKRDAYVDFAHDMLKMMAESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SVN2</accession>
    <name>A0A9P6SVN2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004901</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002453">
        <property type="protein sequence ID" value="KAG0007244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SVN2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="215"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="246"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0007244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="584" mass="64589" checksum="E489D434F064CB9F" modified="2023-09-13" version="1">MATPLDPFDTLCHKVFIANADTGFDQSPPIPTNEETALSLVSRAQVYEFPASYTIPASFTNTSLSTATAVTAPQDRRCYRIHLETIEDLTVQQSVYQILIEAIDPAALLELPFDRSLSGYSSKTRTESCESTLDTPVVLDMGQLSAPSEEEQGSTIVDQQPIENNNKTMLLVPTAEWLRMSGRVRFWREESHRIKSAKREVVLNGLLNERWKPLSSITVSSPPPTSGSLVAATIPPTSLPSPEPSNPSSTVSSLRSPISQEQSPGLTSRPSACKQAFQEHQLDTLAQFMTQFGEELSASSILKGLLIQRQLTEEKVLSWTFDRANLTEQKAEVTTAFLDLGARLGLELVEANIDWDANSTLNQATLNSTDSTATNVVVVTDGNKEKQSTDLTWTFGSKIDDRRLEYWIQNIQQSSLPVLKTDIPIDSTLPLSNPSLNQRQSQQDRKPNPVPAAILKRFLQDRHTIAAGSIQVLMTKVIPSEPSLNAPVTSVSEIPVVRDRSFVLVTSKYALSSTNTTSSSSGLFVHRVGKDVMSLARWASSCGGRLDWLWAWLFASFRKSRYRSSNINDEDSKRRSPRLNDDNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SVR4</accession>
    <name>A0A9P6SVR4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004992</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002490">
        <property type="protein sequence ID" value="KAG0007171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SVR4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31639">
        <property type="entry name" value="F-BOX PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31639:SF256">
        <property type="entry name" value="OS07G0242900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="8"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0007171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="442" mass="50279" checksum="DFF44B4DA2E747E3" modified="2023-09-13" version="1">MIHPLGLPEIRARVAAYLDIRDAINCACVSKDWNSTFLEHVWSHIALEVPSHLPTIEQIRAHSSHIRTISLRSVLPDDYYLLDNLHRLYSLQVAHRHGGTELNLPFLGKLIENHSSSLEQFQLSGRMSHVPHSIFNALGTCRHLKSITLHNLILTVDDLKVLLINCANIGRSGTENGYDNNGLPRSGHGGLSSLVLDAVRIQRYNSDDVSTLPRLPNLEYLAITKSPGILVDGLTTYFTHCPNVKSFHWTEAVRLEVANWVEQIESGKWSDLTCLDFVGQGFGDNELFRMIESLPLPLEKLRVESTFFGRDSFRSLMSLERHYTNLRELNLSGCWNVTSGMVQQIMTKMPLLESLFADYLCVTDVLDASDVDRNGEDNGQDWICKNIRTLRLCINLGGEFDTSSQEYDERQRHVYRRLSNLKLIEILEVGRNFLDRNRGDRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SVX5</accession>
    <name>A0A9P6SVX5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Telomerase Cajal body protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">WRAP53</name>
        <name evidence="2" type="ORF">BGZ80_004687</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002366">
        <property type="protein sequence ID" value="KAG0007410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SVX5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051150">
        <property type="entry name" value="SWT21/TCAB1_mRNA_Telomere"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13211">
        <property type="entry name" value="TELOMERASE CAJAL BODY PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13211:SF0">
        <property type="entry name" value="TELOMERASE CAJAL BODY PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="308"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="455"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="457"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="470"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0007410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="586" mass="64528" checksum="C9D5ABDEFC8A2F90" modified="2023-09-13" version="1">MDIDGTYELEKVEGSMQDGEVAADIGTTMSDNTQELNNQPIQEDASQDWQSQTFQVFECQFAKETTNHGIVKSFTTKNIFNSTVGEARLDMGIKDDHHRMTNGCENNFFKSVKWSPDGLCLLSSSNDNCLRIFALPDATTTNLEDTPLTAGVLIKEGEVVYDMCWYPAMNSQDPTTCCVLSSSRDHPVHLWDAFTGELRCSYTIVDHCEVNIAPNALCFNLDGSKIYCGSNNMIQIFDTTRPGRDSYKRPTVPTRKSRKGQKGVISCLAFNPDHSDLYAAGSYLKTIGLYDSRAEELLLLLRDKDNHKQQAGSHAQKPSSSSPSRPMGGVTQVQFSPDGMYLYSASRQDPLIRCWDIRNTSKVLHRLERPGELTNQRISFDISCDGRWLCTGDMNGNISIFDLSDPESAQDTDPETRLSARIHAHDDVISAATFHPSGSLLATSSGQRKYELLLNSDDSDSSESEDSEDIKENIDTEMKKVEPPSQSKISEPQDPGEPEKATIDNSIRIWTLPGEYVWYVNGQRWNESTSMDTTDPSLASLNPDLSVSLDSGSAVATVATITTAAASITTTAAATVGDRGDSAVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWG8</accession>
    <name>A0A9P6SWG8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Methionine aminopeptidase</fullName>
            <ecNumber evidence="6">3.4.11.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">MAP1D</name>
        <name evidence="9" type="ORF">BGZ80_003457</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.</text>
            <dbReference type="EC" id="3.4.11.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="5">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="5">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="5">Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.18" evidence="6"/>
    <dbReference type="EMBL" id="JAAAID010001916">
        <property type="protein sequence ID" value="KAG0008424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWG8"/>
    <dbReference type="OrthoDB" id="3209743at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004239">
        <property type="term" value="F:initiator methionyl aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01086">
        <property type="entry name" value="MetAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01974">
        <property type="entry name" value="MetAP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001714">
        <property type="entry name" value="Pept_M24_MAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002467">
        <property type="entry name" value="Pept_M24A_MAP1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00500">
        <property type="entry name" value="met_pdase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43330">
        <property type="entry name" value="METHIONINE AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43330:SF8">
        <property type="entry name" value="METHIONINE AMINOPEPTIDASE 1D, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00599">
        <property type="entry name" value="MAPEPTIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00680">
        <property type="entry name" value="MAP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5 6" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="4 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M24" evidence="8">
        <location>
            <begin position="127"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="43"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="283"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="290"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="315"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="346"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="346"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0008424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="361" mass="39366" checksum="3DCF740536ED5D6E" modified="2023-09-13" version="1">MSMLNQALLRSRASILSFARTAIPQRTFVRLHQPQLQHVAHSRQIHLSSSSLHPRKPKNAHGGGIRDRNHFGNYARLAPTSLRLGVAPPDVDSLIPAHIKRPSYALRGEPSEWSSSIPVNSLEAIEGCRKAGQLAKKILELGGTLVKPGVSTSDIDRILHEAIIANNAYPSPLNYMGFPKSVCTSVSNVIAHGIPDNRSLEDGDIINIDITVYLDGYHGDTSATFLVGNVDQPGRELVERTKESLEAAIAICGPGVPLNRIGKTIQSIADQYGYTVSEQFSGHGIGKEFHCLPLIYHHDNDEEGEMEEGMIFTIEPMFCQGTAVGVQWPDKWTVSTADGGRSAQFEHTILITENGAERLTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWK5</accession>
    <name>A0A9P6SWK5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003289</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001862">
        <property type="protein sequence ID" value="KAG0008578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWK5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="6"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0008578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="201" mass="23319" checksum="19BD1B1BDA10852E" modified="2023-09-13" version="1">MHLDDFVIRNTRLEEVDTFIDILETTAEWLQANSINQWSPGSFRAADSRARILDAITAQQCYMIDYRPSKTLNGKDNSGHDVVQIAGLFVINYDNSFDEILWKGFAEDWKDALYLHRLVIRKLYQGLGVTPKIVEFVENKVKEAGRHYLRLDCLAGNASLRRFYREKCRGREKGGLNELSTVWSPELELEFARFEIQVVQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWL5</accession>
    <name>A0A9P6SWL5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_003249</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001850">
        <property type="protein sequence ID" value="KAG0008618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWL5"/>
    <dbReference type="OrthoDB" id="4748970at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF120">
        <property type="entry name" value="KRUPPEL-LIKE FACTOR 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="295"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="323"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="253"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0008618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="405" mass="44548" checksum="F86D91A9D3C34742" modified="2023-09-13" version="1">MDNFSMALDSDIGLFDDCCDQSAIPSFTPHVVAHVSAANNTTFATAGQTFGNNNSYSFPSNDLAAVTWDVAPTKAQLQQLFNSALSDTSATNIMDFTPELSPAMDLATPAANQLRSPFAFDTLGLDELGSSPSIGYQSPMDHQQAFGSQHSQESFDFDFGLDLLPKNTTTWPTQTDFDLFPENSNNNSPSVSSLEQLLMRPVPGEAELSVFEESPLESDLDYFSPLDSCAASPVLGDYTGLFGKSNEAATGAVSSGYQGSGFQPPKRRRRRRATTEDAARVFEDDENDPNARARYKCSVCEKTFSRPFNLRSHRATHAGVKPFVCSHVDEKGEACSWSFARRHDLERHMRSRHSGEKLFKCKTCGAECGRNDAFKRHLQRHAACGMAAMLEQQQQQQQQEQQNGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWX5</accession>
    <name>A0A9P6SWX5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_002958</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001758">
        <property type="protein sequence ID" value="KAG0008875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWX5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="65"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="102"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="146"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="186"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="264"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="565"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="638"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="638"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="666"/>
            <end position="675"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0008875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="688" mass="75980" checksum="12ADE23D30E3EE9F" modified="2023-09-13" version="1">MLPLPSTIVATVYITLITILSCVQFRRSQTPLRFGAVVMALFGLSISAFSIVYTTDKVSLSIFWVYQFVAECIAVTWLIVTMIQLGYTFYPLTRHQTLIWRTAVGSVIIYDLIAISELSYYCYGVWGSGSLSKEGTPILWIYWVRQVAKVLACAVTIAYLFIPLVRHHHSTGVAMIADSNTLAVGTWYLSALGFTSLGYLVMFIYYMTKSKEVFSPQAQALDLCIRLTSCPIFSLPPPQFLINYFRKKYGSAARDDNPNTMIEEGITNDPRPRRPPMLVGQSTSTRRNSNYVFGPGYQERNASTYSSLEIDEDRCKRYLDEEVNIGTTSSLDTAAETSPKLRPLTKLSTLNLKESKASTEGSKNEAVLSSLPISAPTDRSSTPDSEEITMGTHLPSFAPGIALELNEKKETALAARKISRRLTMEGRKDNLDFLNITGLMRRSHCPTTGQVQKSTASIGLGTGPGSHPSLPTSISEISFSPSRHYGDIRERSAQPTALRRGRGGNLSVISDGSIAEDDDKVGLDSKISQDHLYTHTIVGIETPEQEQKDLSDNQLVMDMEQYDTQMDTSSDCASSHHPMIRQSDSEVTEQQQQQQKHDSSGDSSSSKPIKKMSIDNLRRMSRDALTRFQEGVFGASVSLSNSATTGPLSPTILRTERESYGFDAKSTTTTTTSTTLPTQQLSGDDDHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SX08</accession>
    <name>A0A9P6SX08_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_002601</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001647">
        <property type="protein sequence ID" value="KAG0009240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SX08"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0009240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="112" mass="12813" checksum="69A140EFFF079489" modified="2023-09-13" version="1" fragment="single">SAEIDNTAEEYEQQLQQRKSEEMEAIEGQLAQHREEEETRQRREQEVLKEAKDFSLQDQVRVAVTEALNEHSSVTPGVSTVALFLFENCTEDEVLLLEGEIIHNVRDLGGGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXC8</accession>
    <name>A0A9P6SXC8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Dynactin subunit 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_002387</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the dynactin subunits 5/6 family. Dynactin subunit 5 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001587">
        <property type="protein sequence ID" value="KAG0009440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXC8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005869">
        <property type="term" value="C:dynactin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047125">
        <property type="entry name" value="DCTN5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46126">
        <property type="entry name" value="DYNACTIN SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46126:SF1">
        <property type="entry name" value="DYNACTIN SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21711">
        <property type="entry name" value="DCTN5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="Trimeric LpxA-like enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00034706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00034865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0009440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="97" mass="10418" checksum="15B7031351C23121" modified="2023-09-13" version="1">MKIGDHVTIGEGSVIQAASIGSFVSIGKNCVIGKFAIIKECSRIEDNTVIPPNAVVPSFSVYSGSPGKLVDELPESIQEIYEARTKDRYAKFVPSTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXH0</accession>
    <name>A0A9P6SXH0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Sugar phosphate transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_001854</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001434">
        <property type="protein sequence ID" value="KAG0010024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXH0"/>
    <dbReference type="OrthoDB" id="5547497at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004853">
        <property type="entry name" value="Sugar_P_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03151">
        <property type="entry name" value="TPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="14"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="107"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="132"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="154"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="188"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="227"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="285"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="Sugar phosphate transporter" evidence="6">
        <location>
            <begin position="16"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0010024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="338" mass="36857" checksum="47201C3293AD87CC" modified="2023-09-13" version="1">MPSVPCLSLSERQAVFLTVGFYMISALLMVSCNKWALNALRLPWTLLWCQMMIAVALLKFTDYLGVLKMPVIRKDVSKALIPLISINVLGLGVNTLCLVYVDTSFYQIARGLVLPFTVIFAYALLGQSSSKLVLGSCFIVFCGFYTGVTSEINVSQLGVFFGIISSITTSLHAIVIKKSLAAVSNSSIDLVYYNNALSFLAMTPLIFLSGESSSVLEYFNKDGFAAFHSFLFAALITGIFGFLVNLAGFMQISKTSPTTHMISGAVRGVLQTLLGYFAFNDVITTGRLTGIVLILGGGALYTYAKDQEMRANTKPTYIPMTHKDIDNDDEGHKEPEQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXI2</accession>
    <name>A0A9P6SXI2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Epoxide hydrolase, soluble (SEH)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">SEH1</name>
        <name evidence="11" type="ORF">BGZ80_002121</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat SEC13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001512">
        <property type="protein sequence ID" value="KAG0009736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXI2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031080">
        <property type="term" value="C:nuclear pore outer ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035859">
        <property type="term" value="C:Seh1-associated complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034198">
        <property type="term" value="P:cellular response to amino acid starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904263">
        <property type="term" value="P:positive regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037363">
        <property type="entry name" value="Sec13/Seh1_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11024">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN SEC13 / SEH1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11024:SF3">
        <property type="entry name" value="NUCLEOPORIN SEH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="8" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="4 10" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="10">
        <location>
            <begin position="147"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0009736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="203" mass="22242" checksum="4B045852467E85A4" modified="2023-09-13" version="1" fragment="single">AFVAADGQVKIYEAMDVTSLAHWTLIDSFPVGEGPSKDEEGNHCLSWCTSKFAAQMMVVGCAKDHVAKIFRQDLNNKWQACEVLAGHGGVVHDVSWAPNMGRSYHLIATACKDGHVRIFKLTDDSQGGALAGGWTRKMFNVECIADFADHNAEVWRVEWNITGTILSSSGDDGKVRLWKATYTGDWKCMSVVSAEDGPSAFLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXK5</accession>
    <name>A0A9P6SXK5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_002014</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001484">
        <property type="protein sequence ID" value="KAG0009830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXK5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006709">
        <property type="entry name" value="SSU_processome_Utp14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14150">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14150:SF12">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 14 HOMOLOG A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04615">
        <property type="entry name" value="Utp14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="124"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="499"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="574"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="664"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="748"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="932"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="23"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="40"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="81"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="135"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="147"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="202"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="251"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="263"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="517"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="545"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="580"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="713"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="763"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="788"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="834"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="845"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="863"/>
            <end position="885"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0009830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1047" mass="116615" checksum="C3EE2222F2FF9CA0" modified="2023-09-13" version="1">MAPGRRGGGRSGAGGGGGKSSSNSINRKPQANNHSRKARGAAAAAASSGSSKSNIKSLANVFSLEDDDESKSARRRKQYLDEVDNYEYNVDEIEDEDDEEIDSDEAFDEEDEIKYENFKFYGSKSQVKKNKKKQAKAEKGKGKNVDSEDEDMDDQNDSEEDEEEESEEEGAEYMDISEMLDRPEEEEVALPKKTKVAGFNDFESDEEDFTFGGDGDEDEEDEEEEEEEEEEDEDEEDEDEQDDEMEEDGENNSSSLTSFIDSLETKTSKRKQDDSQDSSSKKARKALRERTEAYDESEYNLQAHRSAAAHSINGNINKKKLDIFDLVSTVQDEAGFSSLKKNIQALESGTKKGKTVETLSAPLPKIVQDRLNRQAAYDETKKEVGKWLPIVQKNRQAEHLAFPMNAPPVDAPSSSTLASKFDASTQLEKEVQEVLVEGGMQEKKLMEFEELALNKMTTEEVEKRRSELRMMRDLMFREEIRAKRISKIKSKLYRKIKKKERERNGLTSEEMAELDPEQAREERMLAEQKRAQERMTLKHKNTGKWAKDQLKHGNFDPESRQAITEQIERGERLRRKIQDVDSDEELSGGDSEYSDFDDDDIEGVKARAFDELAQVEHQLAKDEDAAMEAKVGKGVFAMKFMQDAAKRSKMQAQAAADDFRREMMEEDELRNQSSEDEWKTVTKGSKKAGKKAPKEPEAGTVIGAGGRMVFGASSATPASESNDTSASQGKAVKMNSGGQISKVALSAGHTTKVAGPVNVKIAGSSTRSTSNAQDNDSEDDSANPWLQNDKHGQGKIARKNDKGMTKDSSKSDKLQAKLKKQRAAEVGSDDEVQIDTSSYLTLSKDNQKERGLSKEDSDEEESTAPAPTPAASKKAKATKATPAAEPVMVHAKTTAALSQRDLVARAFANDNVVSEFEKEKMEVMEAERPKDVDMTLPGWGSWGGKGSKKKKNVVVKKAQPGDGVEVSKRKDAKLAHVIINEKRDKKAAAYSLTQIPHPFKTWAQYEQSLRAPVGKEWNTNATFQKMTMPRITTKLGKIIDPLSAPFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SY31</accession>
    <name>A0A9P6SY31_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Altered inheritance rate of mitochondria protein 29</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_000944</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0538 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001208">
        <property type="protein sequence ID" value="KAG0011103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SY31"/>
    <dbReference type="OrthoDB" id="937at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018794">
        <property type="entry name" value="UPF0538"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18444">
        <property type="entry name" value="UPF0538 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18444:SF9">
        <property type="entry name" value="UPF0538 PROTEIN C2ORF76"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10209">
        <property type="entry name" value="DUF2340"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0011103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="139" mass="15799" checksum="764314B149C0F619" modified="2023-09-13" version="1">MSASSEPLSNTLAPSTAATLTIRVIKSFEYRTSKNLILHNIDLTNTTVGQLRALIIEKVKTTPGWKPYQTVVFDTLKLYTKAHGAKTMNLIINMDHDEDWILSNDDAILATYGIENETEISIFNRELYEAFKIHPDIKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SY46</accession>
    <name>A0A9P6SY46_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">MHD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_000931</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <location evidence="2">Coated pit</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the adaptor complexes medium subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001204">
        <property type="protein sequence ID" value="KAG0011125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SY46"/>
    <dbReference type="OrthoDB" id="10259133at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030131">
        <property type="term" value="C:clathrin adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005905">
        <property type="term" value="C:clathrin-coated pit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09251">
        <property type="entry name" value="AP-2_Mu2_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14836">
        <property type="entry name" value="AP2_Mu_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.60:FF:000002">
        <property type="entry name" value="AP-2 complex subunit mu, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1170">
        <property type="entry name" value="Mu homology domain, subdomain B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050431">
        <property type="entry name" value="Adaptor_comp_med_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036168">
        <property type="entry name" value="AP2_Mu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043532">
        <property type="entry name" value="AP2_Mu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022775">
        <property type="entry name" value="AP_mu_sigma_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001392">
        <property type="entry name" value="Clathrin_mu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018240">
        <property type="entry name" value="Clathrin_mu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028565">
        <property type="entry name" value="MHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043512">
        <property type="entry name" value="Mu2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10529">
        <property type="entry name" value="AP COMPLEX SUBUNIT MU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00928">
        <property type="entry name" value="Adap_comp_sub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01217">
        <property type="entry name" value="Clat_adaptor_s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005992">
        <property type="entry name" value="Clathrin_mu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00314">
        <property type="entry name" value="CLATHRINADPT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49447">
        <property type="entry name" value="Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00990">
        <property type="entry name" value="CLAT_ADAPTOR_M_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00991">
        <property type="entry name" value="CLAT_ADAPTOR_M_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51072">
        <property type="entry name" value="MHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0168">Coated pit</keyword>
    <keyword evidence="5" id="KW-0254">Endocytosis</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="domain" description="MHD" evidence="10">
        <location>
            <begin position="169"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR005992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0011125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="426" mass="48518" checksum="C0FBBF2323892666" modified="2023-09-13" version="1">MISAFFIYNQKGEVLISRLYRQDLKRSIADIFRIQVISSTDVRSPIITLGSTSFFHVRHENLYIVALTKWNANAALIFEFCYRVINVGRSYFGKLDEEAVKANFVVIYELLDEVLDFGYPQNSDADTLKMYITTESVKSERAIMEDSARITIQATGATSWRRSDVKYRKNEAFIDVIESVNLLLSAQGNVLRGDVAGQIMMRAYLSGTPECKFGLNDRVLLEKDASNRKKSSNTVEIDDCQFHQCVKLGKFDSDRTISFIPPDGEFELMRYRTSDNINLPFKVHPVVTEIGKSKIEYRILVKANFSSKLNANNVVLNIPTPLNTAGVVCSTSAGKAKYVPADNSIVWKIQRFQGQSEYMLTAEADLTAMTHKKAWSRPPISMDFHVLMFTSSGLLVRFLKVFEKSNYQSVKWVRYMTKAGNYQIRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SY56</accession>
    <name>A0A9P6SY56_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">3'-5' exonuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_000871</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001193">
        <property type="protein sequence ID" value="KAG0011181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SY56"/>
    <dbReference type="OrthoDB" id="1920326at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002562">
        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051132">
        <property type="entry name" value="3-5_Exonuclease_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13620">
        <property type="entry name" value="3-5 EXONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13620:SF104">
        <property type="entry name" value="EXONUCLEASE 3'-5' DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01612">
        <property type="entry name" value="DNA_pol_A_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3'-5' exonuclease" evidence="3">
        <location>
            <begin position="248"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0011181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="589" mass="65576" checksum="E4CB87018BF06B4B" modified="2023-09-13" version="1">MSPITNHISSGTRVMLSRAQPHLRLLVSFGPTPFHLAARGGIHGGSFHHSTRHGQKTVKVITTTVTSTNSRTTLSRKTSGSVTTKKIVPLRQVTTLSTALSPMANPTIPIDSSRGIIPPLLSRSATTTSFISFGEQGRMTPDGKGRSKVIKEFRSRSSIAQLSPLRFPPPSSIVSAPPDSLPFLDFRTNDSREVYYTKCDQEADLWLESLESNENDGTKIMRDWGVGCASLVELGAIFIQVKEDLDNQRKIRSMAKLTKELLGHSIEKIESVRMCNWQSRNLSSSQLAYAANDVFVTYEVAERIKLLQKSRPSQDYIVELMTIIDNGAEYIRVRGTLQEREFKPFTEEDIIDEVITVGSSPKPKTKNISESLKATTTIAKTAITREPKPIITTNTVTHTQLSIKPVNAKKPQPIHHLGVMNAWSRPKPQVTIPVSKPKPRFRVSGEPEFPYWNNPNDEQAMQFGSRSTVVIISRNQQKRTLCTSRRLDISSIGTLAMKDTTSKHGSDIEEENNGRDLNSVYVPSRILPESLEGMDTLERNQAVWLEAGGRDLSDEITAQKSDSDDDWHLIQNQKLLQSTMSGSFIADQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SY83</accession>
    <name>A0A9P6SY83_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-acetylglucosamine-6-phosphate deacetylase</fullName>
            <ecNumber evidence="2">3.5.1.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_000983</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>N-acetyl-D-glucosamine 6-phosphate + H2O = D-glucosamine 6-phosphate + acetate</text>
            <dbReference type="Rhea" id="RHEA:22936"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:57513"/>
            <dbReference type="ChEBI" id="CHEBI:58725"/>
            <dbReference type="EC" id="3.5.1.25"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="9">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-dependent hydrolases superfamily. NagA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.25" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010001217">
        <property type="protein sequence ID" value="KAG0011057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SY83"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008448">
        <property type="term" value="F:N-acetylglucosamine-6-phosphate deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006046">
        <property type="term" value="P:N-acetylglucosamine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019262">
        <property type="term" value="P:N-acetylneuraminate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106279">
        <property type="term" value="P:negative regulation of UDP-N-acetylglucosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.140:FF:000023">
        <property type="entry name" value="N-acetylglucosamine-6-phosphate deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003764">
        <property type="entry name" value="GlcNAc_6-P_deAcase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11113">
        <property type="entry name" value="N-ACETYLGLUCOSAMINE-6-PHOSPHATE DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11113:SF14">
        <property type="entry name" value="N-ACETYLGLUCOSAMINE-6-PHOSPHATE DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038994">
        <property type="entry name" value="NagA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="8">
        <location>
            <position position="327"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="267"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR038994-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR038994-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0011057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="356" mass="38592" checksum="1049809B79A1C8C3" modified="2023-09-13" version="1" fragment="single">MQYPLQTPASAPASPEPHTPIREDEPKVIKITNCKILKDHKIVENDAIWVQGGKIIDPHKFFWYQKRLPDQVLDAGGLLIVPGFIEAQINGAFGVDFSVPSDYETYEKDLLKVNRGLLKYGTTSYCPTIVSSSASVYHKVLSHLKPRAGSATTGATILGAHVEGPFINEARIGAHELKVLQASANSGYDDFKDVYGLEGATPEDQGKLSQESQNSVKIITCAPELEGIMDTIPDLVKAGITVSIGHSMANISQAESAVAKGAKFITHLFNAMPQFHHRDPGVIGLLGSRLDLPRPYYGLICDGIHVHPNSVKIAYDSHPEGVVLVTDAMSAMGLAPGNYHLGNMNVTKDEDRVYIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYI5</accession>
    <name>A0A9P6SYI5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Nucleolar zinc-finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ZPR1</name>
        <name evidence="11" type="ORF">BGZ80_000682</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Acts as a protein folding chaperone for elongation factor 1-alpha.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ZPR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001147">
        <property type="protein sequence ID" value="KAG0011446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYI5"/>
    <dbReference type="OrthoDB" id="308464at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.420:FF:000001">
        <property type="entry name" value="Zinc finger protein ZPR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.420:FF:000002">
        <property type="entry name" value="Zinc finger protein ZPR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.1040:FF:000001">
        <property type="entry name" value="Zinc finger protein ZPR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.1040:FF:000003">
        <property type="entry name" value="Zinc finger protein zpr1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1040">
        <property type="entry name" value="ZPR1, A/B domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.420">
        <property type="entry name" value="ZPR1, zinc finger domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004457">
        <property type="entry name" value="Znf_ZPR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040141">
        <property type="entry name" value="ZPR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042451">
        <property type="entry name" value="ZPR1_A/B_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056180">
        <property type="entry name" value="ZPR1_jr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042452">
        <property type="entry name" value="ZPR1_Znf1/2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00310">
        <property type="entry name" value="ZPR1_znf"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10876">
        <property type="entry name" value="ZINC FINGER PROTEIN ZPR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10876:SF0">
        <property type="entry name" value="ZINC FINGER PROTEIN ZPR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22794">
        <property type="entry name" value="jr-ZPR1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03367">
        <property type="entry name" value="Zn_ribbon_ZPR1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00709">
        <property type="entry name" value="Zpr1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Zinc finger ZPR1-type" evidence="10">
        <location>
            <begin position="54"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="Zinc finger ZPR1-type" evidence="10">
        <location>
            <begin position="315"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="233"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="283"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="522"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="532"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00054139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0011446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="553" mass="61564" checksum="59B76119BF8A31C8" modified="2023-09-13" version="1">MAEETKNNNDLGLAASVANAASFDKKEHNAQDTPADGPLFQDIDGDQEVTEIESLCMNCHENGTTRLLLTRVPHFREVIIMAFDCPHCGFRSNELQQANAIAVGGAIYTCKISTKADLNRQLVKTDTAVVKLPDIDFEIPAQRGHLTTVEGLLQTAIDDLESGQPVRKHMDEALYQQIDNIIKKLQEFIENKAPFTIILDDPAGNSYIESLDAPKLDDKLELSVYMRTRAQERAMGLSVPDEDEAEKTEEAAAPVPMPRDQQIEHAQKQLWEAGLTEADLEKEREAKRQAAIEAGEDPDKAVEEEELPEVLSFPANCSSCNAPSDTKMHILDIPHFKEVIIMSTTCDECGYKSNEVKAGGPVSEFGKRITLKIEDAEDMSRDILKSETCGLSIPEIDLELNSGTLGGRFTTVEGLLRQVHDELSSKVPAEAENQPERRQVFTKFLDKLEKVLSLEIKSTLILDDPLGNSYLQNLYAPEPDPAMTIEEYKRTPEQDDILGLSDMRLENYEDDHHHTKTIEAIPEEKEEEEKVEELTEEQKEAEEIAGGGVSGGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYK2</accession>
    <name>A0A9P6SYK2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Udp-galactose transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_000627</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001131">
        <property type="protein sequence ID" value="KAG0011525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYK2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015165">
        <property type="term" value="F:pyrimidine nucleotide-sugar transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007271">
        <property type="entry name" value="Nuc_sug_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00803">
        <property type="entry name" value="nst"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10231">
        <property type="entry name" value="NUCLEOTIDE-SUGAR TRANSMEMBRANE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04142">
        <property type="entry name" value="Nuc_sug_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005799">
        <property type="entry name" value="UDP-gal_transpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="89"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="113"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="181"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="214"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="246"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="277"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="302"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="342"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="357"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0011525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="377" mass="40598" checksum="197A7DE96FF6A7E9" modified="2023-09-13" version="1">MALAQGPGRKPFYSSTAVFINEIVKLIVCIGMTIHGTIKDTGRFYLQDFLNDVFGGDAWKLAIPAMLYAIQNNLQYVASHALDPSTFQVTYQLKILTTAIFSVLLLNRSLPALKWMSLVMLTAGIALVSLEESNNRARANQRSNSDPDSTSSALGALLDEQKNNVLETAAAPAPSNDRPEFFVGLLAVMIACILSGLAGVYFEKILKNTKESIWLRNIQLSFFSLPFSLLAVYLKDGEGVTEQGFFAGYDMLVIAAIACQSAGGLIVAVVVKYADNILKSFATSVSIVISAIASVALFGSRIGTVFVIGTALVLGATYLYSLPDKPTVKYVDLGSQLDTFHAEEGRMGSPRQGSNDTLSTPTTSSPSVRLDRIRGQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-06-18" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYT0</accession>
    <name>A0A9P6SYT0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BGZ80_000131</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001020">
        <property type="protein sequence ID" value="KAG0012209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18579">
        <property type="entry name" value="ABC_6TM_ABCC_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000013">
        <property type="entry name" value="ABC transporter C family member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000006">
        <property type="entry name" value="ATP-binding cassette, sub-family C (CFTR/MRP), member 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000997">
        <property type="entry name" value="Multidrug resistance-associated protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000163">
        <property type="entry name" value="Multidrug resistance-associated protein member 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044746">
        <property type="entry name" value="ABCC_6TM_D1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF443">
        <property type="entry name" value="MULTIDRUG-RESISTANCE LIKE PROTEIN 1, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="217"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="261"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="356"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="449"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="891"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="931"/>
            <end position="953"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1026"/>
            <end position="1045"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1113"/>
            <end position="1134"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="214"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="584"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="891"/>
            <end position="1168"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="1204"/>
            <end position="1464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0012209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1469" mass="163101" checksum="339CFC51BF5C8246" modified="2023-09-13" version="1">MAVGPLDQLEIAKRRVCQNWVNASNKSYELGPGAIAMLITYSIAIILNKNEHLYEIRSSDYLFLYYLCTTFTCSISIYILQSEAEPSDLSSLRLLNTFTIIVILAFLFEAIPRTNTRVQQESREKEHLSDYDQANLLSRITYHYIQRIVSLGATRPLNEEDLKNTAPGYLKTRVNFRRISTSWENNIARSRASHGGRSPSLILTVLSTYRIKIVAMLAVRLIALSLIYLAPMLLGRLLKFIDEYGSTSKEGGRGPPPLKEGLLITTGILACNVLSTLLFAFSVAGNMDVGVSAYVGIEAMIYRKSMTLSPQARQKSTLGEVTNHMSVDTEKWLSSAYYLPHIITSPIELAVGIRMLYGLLGWSLIAGLTVFAIIMSIHAKMARSMNGYQDGMLRFTDLRLRLITEILSNIKTVKLYGWEDAFRKKIDALRTKELSYLKPLATIRSISKIGYSSISLLMALATFAIYSTVGGPDMTPGKMTPQIVFVSISLFNMLNEPLGMASYVISQTIALRIANLRIQKFLLQEELDTTIVQRYGRQPPRSPSNKGRKDQNLSIDIENGTFAWETEVGFPTTVIDSADHAEDVRQPLLSGSSTPNPTPARPVLNNISLQIPEGYLTAVVGRIGQGKSSLLSAIMGEMYKKQGTVRIYGELAYVPQQAWIINATVCDNIVFGRPFDQQLYDRIIYASGLRPDFEMLPAGDQTEIGERGINLSGGQKQRVSLARAVYQDADIYLLDDPLSAVDAHVDQHLWNNVIGPNGLLKNKTRVLVTHGIHHLEHVDQIVVFKDGTISETGEYKQLMNNGGAFNQLIKDYLVTATNKHKYGGSRVESGIDEDSQRKTHVAKGATVTSDDGGDNSHGVGELVAEEKMEDGRVGWYVAATYARAVSYRRTFICVVLFILGQGSHISTNFWLSYWINDTGHQDREVRALSYYLTIYGLLVIVYTIFDVAINYFCEVTCGMQGSITLHERLLTRVLRLPMRMGRIVNRFSSDINSVDAVLPEEINRLFTFMTFVGGTLALIAYSTPAFLLAIPILGIAVYIIQDYYIKSAGSLTRLFSVSKSPLFQHFSESLAGVSTIRVTKGLREQFILQNEVLGDVVVERMNMVFILGRWLQVRLEIVAAVAIFLFTSLAVINIDRLDSSLVGLTLTYGLGVITLTNYLVRTVSEVENLLVSVERIQEYSEKPMEAPAATGVRLPQNWPQKGLIAFKHYSARYRVGLNLSAKDVSFTVEPGQKIGIVGRSGAGKSTLTLALFRIIEAADSYWVLASDPSSSDSPIDPAIYSSSAGGLIEIDGIDISTLGLRDIRQHLAIIPQDPTLFAGTIRDNLDPFNELSDSDIWEALERAHLKAYISSLAGGLSFEVAQNGGNFSFGQRSLICLARAMLRKTKVLILDEATAAVDVETDDLIQKTIRKEFQDRTILTIAHRIKTVMDSDKILVLENGCVQEFDAPSKLLDRHTSLFYSLARQAGEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYT9</accession>
    <name>A0A9P6SYT9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">MPN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_000283</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001054">
        <property type="protein sequence ID" value="KAG0011987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYT9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08067">
        <property type="entry name" value="MPN_2A_DUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050242">
        <property type="entry name" value="JAMM_MPN+_peptidase_M67A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10410">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102712">
        <property type="entry name" value="JAB1/MPN domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MPN" evidence="2">
        <location>
            <begin position="23"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="296"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="452"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="306"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="454"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="496"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0011987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="537" mass="58706" checksum="0943AC8655CF1C75" modified="2023-09-13" version="1">MVKCEPFCGQPNSGVQGCQPFGIKVQSNVLLGMDFHAHLMTTEIIGFLAGEWNTATRMIHIKAIFPCRSLPTGQNHINVEMDPTSELEVRQEIEKRNMRIVGWYHSHPTFTPDPSLVDIENQTSYQSLFKDDSVNEEPFVGAIVGPYDERLPGLSSVINWFYISRSPQERGHPKRLLYDLIEDTELTEEEAGSWTKLFDEYRDSPERTNFKEQWRQDEPETKLQKMLVSLGRRMPWLRNNLLKGKESAEVAQSIENTENVESTANAESAANVESAANAESTANAESTASAETIANPASAGSVANDTSAENTENAESAESAENTEKVEGTENVSVSKDESPSITVDVLDAAEPVDMAIEAEPVNISIEAEQVNTSIETEPTDTSIEAEPTNMSIEAEPSNMSIEAESADMSIEAESANMLIETEPANIAIETEAIPQIENEDMKPSSEIPRAEEIAPPSEAPAESAQSMEGIEPTGHDSFEGTLSSDASQEHGLVRSLSNESSESTGSKSFSGLSSLINDPFLILVEQELVTWEPVTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYY4</accession>
    <name>A0A9P6SYY4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Metabotropic GABA-B receptor subtype 2, isoform C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">GABA-B-R2</name>
        <name evidence="12" type="ORF">BGZ80_011567</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000946">
        <property type="protein sequence ID" value="KAG0012707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYY4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038039">
        <property type="term" value="C:G protein-coupled receptor heterodimeric complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004965">
        <property type="term" value="F:G protein-coupled GABA receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007214">
        <property type="term" value="P:gamma-aminobutyric acid signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15047">
        <property type="entry name" value="7tmC_GABA-B-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001828">
        <property type="entry name" value="ANF_lig-bd_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002455">
        <property type="entry name" value="GPCR3_GABA-B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017978">
        <property type="entry name" value="GPCR_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10519:SF20">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR 156-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10519">
        <property type="entry name" value="GABA-B RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00003">
        <property type="entry name" value="7tm_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01094">
        <property type="entry name" value="ANF_receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="Periplasmic binding protein-like I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50259">
        <property type="entry name" value="G_PROTEIN_RECEP_F3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 12" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0807">Transducer</keyword>
    <keyword evidence="2 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="259"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="296"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="328"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="368"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="426"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 3 profile" evidence="11">
        <location>
            <begin position="259"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="632"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="711"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="674"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="745"/>
            <end position="754"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0012707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="764" mass="84870" checksum="021842366A2E70ED" modified="2023-09-13" version="1">MDNIERQAQKNGITIGYRRTFWEMGTSSDVGPGLDGLKDSGQQIILVAAVGTPQVRLIMEAVGLVSKNYVWLTINQVTEPLLGMEGSTLEPMDLNGLFMFDNMLRLHGYPPYEAFLDRWAALDPTEYPYAGKRDISSNEAQAYSCMMVIANGFANAVKGNSTALRMLASGKLGSKLTPLNMNTNYTGPGGPMAFDEDGDVVYGNFILYNFQNGRVVEIGTSYSGFLTLSSSPMYYDGTYNAPSDTAPLKVLNPVFSSPIAIVIIIVAGLGILFSVVTMIVVVLYRDAHVIKASSPLFCCLELCGFILLYSSVITGLDIPNKFTCILRPFTLNVGFILVVSNIVAKNFRVYRIFHNIYVTKKVIRDSHLLKIVGAILAVNLTVMIIWFLRTPPTLEQIIMQDLTTYWDCSSQSGKMFLPQDQYLTKFFLTNVVLLFGTTVSLMFMFLPKLMKLYSQIECGMQGDRAEIAEESSFNGLFNRPSWLNTSSGIGSSMGEYVPARKGSVVSIEDSKGDTLRESHFGYMGVKFQNRYMPFLSSWCMRRIVLFPAEKYFTAFESGKPEAGRTFTFRAVHILSKEPDNYILQVTGRGRLDFLLQVEDEEHLMYWYSLFEFKQGNTFTSSPMGSTTTLPLGNMPMSLAQGRTESDQTLHPPYVNSGKSSRPKKGSGDEGCYFSRTTRGSPSHSLGDPYQYQQHCHTSSSYTMASFTASPRSSFGEVERPRTVMDPPSRQTTLGPLDMDPDDFSDSVGDSSLSPSPYPSDARLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYY5</accession>
    <name>A0A9P6SYY5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">serine--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Seryl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">SARS2</name>
        <name evidence="10" type="ORF">BGZ80_000105</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.11" evidence="1"/>
    <dbReference type="EMBL" id="JAAAID010001016">
        <property type="protein sequence ID" value="KAG0012234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYY5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004828">
        <property type="term" value="F:serine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006434">
        <property type="term" value="P:seryl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.40">
        <property type="entry name" value="Serine-tRNA synthetase, tRNA binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002317">
        <property type="entry name" value="Ser-tRNA-ligase_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042103">
        <property type="entry name" value="SerRS_1_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00414">
        <property type="entry name" value="serS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11778">
        <property type="entry name" value="SERYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00981">
        <property type="entry name" value="TRNASYNTHSER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="9">
        <location>
            <begin position="270"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="135"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="527"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="104"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="530"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0012234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="562" mass="61235" checksum="A63D0631459CBCBE" modified="2023-09-13" version="1" fragment="single">MLRFAGTVPRRTIETSFGSSQWTRILCPGRLHHERSLSTSSRLWKALDTSAQPTPPSSQPHPVPALNLKPHINFKALTNPESAAAMAANIKNRNLPDSISVAAVTALHKTVAEKTQQLDKARAERNRIAAEMKALFSSTGSKGKKKQQQTTEDASGAASTELSREANEARRLELVERGRVLKEDIHAQEAELALLETQLYDQAILIPNNTHPSSPIGPEPAAQLVRVFGVPRLNNGIKAHAQPGTEQLGGIGGEEGGVLLGDVSNYPLLDHVALSRQLDLIDFESATNVSGSRWYYLKNEAALLELALIQFATQRAVKAGFMPVITPDVVRPEVVQACGFQPRDEASQTYWVSTIAPGSNRAATPEGAHHHQHSALCLVATAEIALAGMNLNKVLEENQLPIKMAGFGRAFRAEAGSRGAEVRGLYRVHQFSKVELFVLSKADPGESDRILEEIREFQESTFEELGLCFRVLDMPTEELGASAYKKYDIEAWMPGKNAWGEISSASNCTDYQARRLNIRYRTNKILNRTDNSSLPPSSSSSSSASSSDDSSLTPSSNSHTTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZ93</accession>
    <name>A0A9P6SZ93_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_011110</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000852">
        <property type="protein sequence ID" value="KAG0013396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZ93"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0013396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="502" mass="56897" checksum="481403EE97F550FC" modified="2023-09-13" version="1">MDLTSLQSATSIALKIPEILELIASFIGENKHLAIHPNSTIGSISAGIRNATHVQYLDLWTDIAEGQYPLPFNKLRTLHITHRYPKDPNFVISQVADLIMRNGDTLQDVMLCRLYEPSTNAMWEAISSCKRINKVRFHHCTVDEQIWNAISKVRRLIFTHSYIVFSSVKAPLTAASPPKLLNLQYLEMFRTVGTQGGGFIGIIQHAPNLSTLRFDPDLNAQTVPYAHQFATALKGCRNLKHLILDNTVLSGEGNTMILDSLTDSKTLHWSVDGFPEQAIRSLMSRHSKTITDLYLTGTTGLTSRMAQTIMTGCPMLESLTLNMISGTDLVRIVEADQENQDGFEDTDQVIVGEDWVCLGLKELKIEFDLSSKEMNIDRDTPEGEAMFQRQQQLEQYHAFRQIGRLIHLWRLDISGNGFRAGNERTLDLRLRSNGGGLEGMMALRDLRRFHFENTKQELSEGEIDWMISRFPRLGSLMGTYHSDEPKNTDLHTYFWKQAQEGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZR0</accession>
    <name>A0A9P6SZR0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Tetraspanin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_011272</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000888">
        <property type="protein sequence ID" value="KAG0013129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZR0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018499">
        <property type="entry name" value="Tetraspanin/Peripherin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00335">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="35"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="81"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="110"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="208"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0013129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="248" mass="28412" checksum="BA9FFE75846E5AAC" modified="2023-09-13" version="1">MNFSPNRQDEGRLRLEQEREYQKTRKLRTWTKSKVALLVANTLLFIYSVGWTVVMAMSWKGAAWTKPYLDSGIMIVANRKLLYIMTVAAPFGVFIAVTGYVGIFAQNRRILSIYTILLWPLLALIVSIGYICFRRKNPFLHLKLKSSWINGYTRDDRLVIQNALSCCGYRAPGDYPSYDLHCFPRASLPPCENLFLTYQQDLLSNTSFSAFSIMALQLVVMIVALLCSNHVDNLYRTANPITPKLYTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZR3</accession>
    <name>A0A9P6SZR3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_010436</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000726">
        <property type="protein sequence ID" value="KAG0014436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZR3"/>
    <dbReference type="OrthoDB" id="2400822at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040337836" evidence="2">
        <location>
            <begin position="22"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0014436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="190" mass="20964" checksum="FCE213151EAEF8A7" modified="2023-09-13" version="1">MLATIFYGVASLVLCVMISNATGPAIDYSHLSKPTATVSSVPPVPAVALSSLSSFSFSKDELDSLLATAHSKLSNYNLERIIGSRSINKPHSFRSWRLSAKRRENTATKATSTSPYVYGYDQSEGRPQRSTYSPPAAYSADDYEQYERRHAASFNRSESAFCGTDGIYSNQEQSQQDWKTQMPINVLSKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZY4</accession>
    <name>A0A9P6SZY4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AAA-ATPase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_010966</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000824">
        <property type="protein sequence ID" value="KAG0013602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZY4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018631">
        <property type="entry name" value="AAA-ATPase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34825:SF1">
        <property type="entry name" value="AAA-ATPASE-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34825">
        <property type="entry name" value="CONSERVED PROTEIN, WITH A WEAK D-GALACTARATE DEHYDRATASE/ALTRONATE HYDROLASE DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09820">
        <property type="entry name" value="AAA-ATPase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA-ATPase-like" evidence="1">
        <location>
            <begin position="48"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0013602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="306" mass="34644" checksum="12A90E55449A62AC" modified="2023-09-13" version="1">MFAETDTVQVIVRPPSYERTLLNIVKYDSRLGDLAWKEDTFRSFPVHGVNNFKTLRQRPELCFFDKTAFIMALESFSEPVLVFLRPRRSGKSLGLSTLAHFHGREHLPDYKPLFEGLAIDEHMKKGDEATHNLSQMLNESIKRFYMTYEPYLRMSVDYLIANSIKDNAAESITACVDIVHDLHYGGRIRQLSNEYPVPIDSVQWKLPRRSNVDNVLEGFWASVKSGLGYREIAKCYITGVSPQSLVDNTSGLNVVQYVSWGPELASFCGLTGADVCCAGAPWEAARSYQFDLIWMSGKVSLSFIST</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T082</accession>
    <name>A0A9P6T082_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Restriction of telomere capping protein 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_010134</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">May be involved in a process influencing telomere capping.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RTC4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000674">
        <property type="protein sequence ID" value="KAG0014957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T082"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039024">
        <property type="entry name" value="RTC4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028094">
        <property type="entry name" value="RTC4_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41391">
        <property type="entry name" value="RESTRICTION OF TELOMERE CAPPING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41391:SF1">
        <property type="entry name" value="RESTRICTION OF TELOMERE CAPPING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14474">
        <property type="entry name" value="RTC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01312">
        <property type="entry name" value="RTC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Restriction of telomere capping protein 4 C-terminal" evidence="9">
        <location>
            <begin position="869"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="700"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="729"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="18"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="38"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="63"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="170"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="243"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="269"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="292"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="307"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="348"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="386"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="407"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="418"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="439"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="461"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="478"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="512"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="548"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="574"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="729"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="777"/>
            <end position="789"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00015162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0014957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="977" mass="108955" checksum="2B44D6C0962FAA52" modified="2023-09-13" version="1">MIDSSVDVFMKVTRHHQRFPDSDDETGRRGKARDQPKSESASPFLTTTNTLQQTHKFKNKHKEHYEKGSKSDIRKSSHSSKIESIHRKEPSAPMLTTVNRFPPRRKELNPDDESVDIQHLQRPFLLSQRHQSGSNEPRSRSLTEDRRKLSSPKSKERFTSPGGREGFASPERKGRFSSPLKDRHQQYSPTAASPSKVPIKGTIIDPPSVSTTHTESPSFSPPSPPPRLNFGKEVISPKRSRKPTSERRKEPIESLPSLPDSEEEYDALSYKDRMRLGDETKAKNKIREKQRSTCPPSSNDGNTQKHTPKEKEIKESDENSQKGCPEPNSDSDLEDADLFKAQPLGFNASSKSFSKLTSTTASSDATDTTSPRHSTIFGASERKAASASTESTLKNKGKTDSTLSRSQSKERKSRTVVDEIEPFSSDDSDADFSNNSRQARRDPVRGVERPGRGSDALSKVASRDTKAKESRVSNLMRPTDDDRETFKDLIPKGTHYKGKESPMAKQMTTSNKGHENLATKDRHRDFFDLSHRQKPRSEAPLKSKKATETTFNRNKGLTNGDIKKANIHSRSVKRSASPSSSSETELTGLSELGVMTSAEKARARAVTPPGRGTSKTTNKDKDNTEVLTPKSGGGFHLPSPRKKKPRMSISSELMFLSDDDLPNPGLVDTNDTDNVCPYCGDPLPKIKSARLASALAKVQASVKERRQQPQPQPQQQGRVVIDLEDDLSNSAKGTLENNSLTPLRGDSSVGKSQPRPRRLDRLKRNMASDTKSSIGENEPDEEELGELEESTSSSKGVSLMEKFEFCRVHFAEERIVPLGMEKNYPLHIDFSQLAGRVRKMEAELRKIIDKTEPSIFLEQALSRYKSMGTLGARHPHVVLANVEQTMPGYYGSKGSAELSKILAKLFLETSILTYDLAHPQKPIEYIQQVLVPEAGLRLIVEDQANLDANNVISLEKARTIMLESVEYGNYMYDIHNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0C3</accession>
    <name>A0A9P6T0C3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_009997</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000650">
        <property type="protein sequence ID" value="KAG0015197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0C3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0015197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="111" mass="13289" checksum="7BE471FF012B9DCF" modified="2023-09-13" version="1">MAPKSKTPYRDERRREAIARMKELMGESFTEDMIHEDLRPNAHDDFLDMVLIADLENRCDLDDSMMKLATDFMKGCGIDLRTNGTYYNKPVLQRLRKEWKWDRENGEFRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0E1</accession>
    <name>A0A9P6T0E1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10 11">U6 snRNA-associated Sm-like protein LSm1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11 14" type="primary">LSM1</name>
        <name evidence="14" type="ORF">BGZ80_009591</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.</text>
    </comment>
    <comment type="function">
        <text evidence="8">Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated. Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of the heptameric LSM1-LSM7 complex that forms a seven-membered ring structure with a donut shape.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Interacts with SLBP; interaction with SLBP occurs when histone mRNA is being rapidly degraded during the S phase. LSm subunits form a heteromer with a donut shape.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
            <location evidence="11">P-body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000589">
        <property type="protein sequence ID" value="KAG0015843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0E1"/>
    <dbReference type="OrthoDB" id="10263346at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990726">
        <property type="term" value="C:Lsm1-7-Pat1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000290">
        <property type="term" value="P:deadenylation-dependent decapping of nuclear-transcribed mRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01728">
        <property type="entry name" value="LSm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000021">
        <property type="entry name" value="U6 snRNA-associated Sm-like protein LSm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034104">
        <property type="entry name" value="Lsm1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044642">
        <property type="entry name" value="PTHR15588"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15588">
        <property type="entry name" value="LSM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15588:SF8">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 11" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 11" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Sm" evidence="13">
        <location>
            <begin position="8"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="96"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00056858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00062159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00067756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU365047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0015843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="136" mass="15692" checksum="AADEAC3013100E42" modified="2023-09-13" version="1">MDSFQVFTTSTSLVDSVDKKLLVVLRDGRKLIGILRSFDQFANLVLQDTIERIYVGDTYGDIHRGIFIIRGENVVLLGEIDEDKEDELPLREVPVEEVLQIQREEMEAKVKREKTKHRMLSEQGFSVDTAEFGELY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0F0</accession>
    <name>A0A9P6T0F0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Histidine--tRNA ligase, mitochondrial</fullName>
            <ecNumber evidence="3">6.1.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Histidyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="primary">HTS1</name>
        <name evidence="18" type="ORF">BGZ80_009556</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the aminoacylation of histidyl-tRNA in both the cytoplasm and the mitochondrion.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>tRNA(His) + L-histidine + ATP = L-histidyl-tRNA(His) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17313"/>
            <dbReference type="Rhea" id="RHEA-COMP:9665"/>
            <dbReference type="Rhea" id="RHEA-COMP:9689"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78527"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.21"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.21" evidence="3"/>
    <dbReference type="EMBL" id="JAAAID010000584">
        <property type="protein sequence ID" value="KAG0015901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0F0"/>
    <dbReference type="OrthoDB" id="1906957at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004821">
        <property type="term" value="F:histidine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006427">
        <property type="term" value="P:histidyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00773">
        <property type="entry name" value="HisRS-like_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00859">
        <property type="entry name" value="HisRS_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01200">
        <property type="entry name" value="WHEPGMRS_RNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.800:FF:000015">
        <property type="entry name" value="Histidyl-tRNA synthetase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000021">
        <property type="entry name" value="Probable histidine--tRNA ligase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="entry name" value="Anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.10">
        <property type="entry name" value="S15/NS1, RNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00127">
        <property type="entry name" value="His_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015807">
        <property type="entry name" value="His-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041715">
        <property type="entry name" value="HisRS-like_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004516">
        <property type="entry name" value="HisRS/HisZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033656">
        <property type="entry name" value="HisRS_anticodon"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009068">
        <property type="entry name" value="uS15_NS1_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000738">
        <property type="entry name" value="WHEP-TRS_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00442">
        <property type="entry name" value="hisS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11476:SF7">
        <property type="entry name" value="HISTIDINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11476">
        <property type="entry name" value="HISTIDYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13393">
        <property type="entry name" value="tRNA-synt_His"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00458">
        <property type="entry name" value="WHEP-TRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001549">
        <property type="entry name" value="His-tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00991">
        <property type="entry name" value="WHEP-TRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47060">
        <property type="entry name" value="S15/NS1 RNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00762">
        <property type="entry name" value="WHEP_TRS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51185">
        <property type="entry name" value="WHEP_TRS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 18" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WHEP-TRS" evidence="17">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="16">
        <location>
            <begin position="78"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="44"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="147"/>
            <end position="149"/>
        </location>
        <ligand>
            <name>L-histidine</name>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>L-histidine</name>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>L-histidine</name>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>L-histidine</name>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="345"/>
        </location>
        <ligand>
            <name>L-histidine</name>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="349"/>
            <end position="350"/>
        </location>
        <ligand>
            <name>L-histidine</name>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00058343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00067413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR001549-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAG0015901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="551" mass="61524" checksum="3FF0DBC95A7C33ED" modified="2023-09-13" version="1">MEELDRRITEQGDLVRSLKSSKADKDKIAAEVATLKALKAEREALAPSDKAAAASGPSTPKPDDKKAKGGFTLKNAKGTKDYTPQEMAVREKIFATIIKVFKKHGGITIDTPVFELKEILSGKYGEDSKLIYDLEDQGGEKCSLRYDLTVPFARFLAMNGKEYQNIKRYHIAKVYRRDQPAMTKGRMREFYQCDFDIAGTYDPMIPDSECLRVLTECLTALDLGDFTIKINHRKILDGIFEVCGVPTDKTRTISSAVDKLDKLPWEEVRKEMTEEKGLDPKAADLIGEYVRLKGGEELLERLYSDAKLSNSPRAVEGLDDMKLLFKYLNVLNVTRYTSFDLSLARGLDYYTGLIYEAVLEGSAPPTLANGEKARATMKKGTDELDESTVGVGSIAAGGRYDNLVGMFSGTNKKGQPNLVIPCVGISIGVERVFSILMQKQKRDEIKSNEVEVYVVGLGGVEVEERMKICTELWDAGIKAEFAYKLKPRTQNQWDVCDRDMIPFAVIVGGDEISKGLVKIKDMRTKDESQKGGLEYPRTEMISELKKRLAEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0I0</accession>
    <name>A0A9P6T0I0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_010210</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000688">
        <property type="protein sequence ID" value="KAG0014815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0I0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0014815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="410" mass="46253" checksum="12747DB1BAF2D42A" modified="2023-09-13" version="1">MTSPKVILSKNDRRAFDVTAPPDTNITQKCMEKSNPLHGYTESIQGRNNHTVQVPTRNRYLTISKSSLGTDFEKLEKAAKNWKSKRRCVLQVHGNEIRLEPLAFHPDDKKEPWFDAVASKVVNRESKFKWSRDPKDIRIHKAKVVCAITLIAITLRVRGDMQGTATVFAYAPETIASDLRVNKLAEVFGTDMIRYLLEDIFLQIKTSSIAPAPQTLLIAARDLVVAYLERQDHRMLVQKDPEALNMKLSRLFTFLDNIDDREQPTLWLLAIKTSIAYAAIICTAYDMAHENERYHGFFAVADKGVDMVVNAAVGQVPVGVSVDSTDIESIQDITWANTESRLNKHDMASKLINDALASFNHSIIQHANKGYIMMRSQESSLQVNAEDAKEYAITTTGYLRSLMPEDVELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0N5</accession>
    <name>A0A9P6T0N5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Insulinase (Peptidase M16)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">IDE1_2</name>
        <name evidence="11" type="ORF">BGZ80_010020</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000655">
        <property type="protein sequence ID" value="KAG0015145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0N5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043171">
        <property type="term" value="P:peptide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000003">
        <property type="entry name" value="Insulin-degrading enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000005">
        <property type="entry name" value="nardilysin isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000004">
        <property type="entry name" value="Putative insulin-degrading enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.830.10">
        <property type="entry name" value="Metalloenzyme, LuxS/M16 peptidase-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050626">
        <property type="entry name" value="Peptidase_M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032632">
        <property type="entry name" value="Peptidase_M16_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054734">
        <property type="entry name" value="PqqF-like_C_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43690:SF18">
        <property type="entry name" value="INSULIN-DEGRADING ENZYME-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43690">
        <property type="entry name" value="NARDILYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16187">
        <property type="entry name" value="Peptidase_M16_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22456">
        <property type="entry name" value="PqqF-like_C_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="LuxS/MPP-like metallohydrolase"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M16 N-terminal" evidence="7">
        <location>
            <begin position="47"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M16 C-terminal" evidence="8">
        <location>
            <begin position="223"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M16 middle/third" evidence="9">
        <location>
            <begin position="408"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="domain" description="Coenzyme PQQ synthesis protein F-like C-terminal lobe" evidence="10">
        <location>
            <begin position="801"/>
            <end position="900"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF22456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0015145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1004" mass="114201" checksum="CBDA0B5F461335B5" modified="2023-09-13" version="1">MAIETPSPEGFELSPDGTHAVFRKAIEISPNDERSYRLLRLMNDLEVLVIHDPKADKSAACLDVHVGHLSDPASDNLQGLAHFLEHLLFLGTEKYPRENEYKEFLSLHAGKSNASTWLDNTEFHFEVGHAHLEGALDRQVRASITSPSLQFAQFFISPAFNVSCKEREIHAVDSEFKRNLQLDSRRIYQIAKHLSSRDHPYWHFGTGNLLTLQEGPKEEGIDSRNELIKFYHKYYSANIMKLVILGREPLDVLAGWAVQKFSEVRNLGVAPPAYPSPPLTSKELLTTVYIKPVRDTRSLEIKFLIPGTTPYYTVQPTSYITHLIGHEGSGSILSLLKRKGWANGLSAGCSSGGIGHEFLKITIDLTSEGLLHHEDITIIVFQYIQMLRDEGVKDYILDEEESLASIAFRFKEMQPAAEYVTKIAREMQQGYAPEWILSGSMLIRARNTDLVMNYINKLTVDRWRGQVVCQDVSKVPGGAFTETERWYGTPYHVDSVSPELLKRLQQIGRNPELHLPPPNEYIPKDFETGKVDTPNPQMSPVLVQHTPLTRIWHKKDDVFWVPKVHLYFRLVSPIATLSPNHLVKSILYMKLVQDVLNEDSYSAALAGLSYSLTSNMEGIILKVEGYNDKALLLLQKVVQTMKTLQVDNERFYRIKDDVERQHRNHSLNNPNILAIYYEKYLNSEKQWTFAERLEELQGITPEDLQRFIPQLLDHLHIEGLVHGNMSISQAVEAGNIVEKGLAPRALSPFELISMRSIILPEGCRAVYQRDVIDPSNLNSGIDYYIQTGFGADKTDRAFVQLMAQIIQEPCFNQLRTIEQLGYIVLSGVRQIGGTLGVVIVVQSERDPIHVENRIENFLRVRIANMLESMTEEAYQKQVQSLIQKKLEKHKNLKQETTRYWDQITSGFYNFEEVQEDVQELEKITLGTIRIFFSKLISPDVAQSKKLSVHFRSLRLPPNGSGKEGDELVLKDGTVIIKDVDLFKANSKLSAALHPTLDFLRTPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T149</accession>
    <name>A0A9P6T149_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_008529</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0357 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000465">
        <property type="protein sequence ID" value="KAG0017199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T149"/>
    <dbReference type="OrthoDB" id="447314at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018559">
        <property type="entry name" value="DUF2015"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28023">
        <property type="entry name" value="UPF0357 PROTEIN YCL012C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28023:SF1">
        <property type="entry name" value="UPF0357 PROTEIN YCL012C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09435">
        <property type="entry name" value="DUF2015"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040514090" evidence="3">
        <location>
            <begin position="21"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0017199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="127" mass="14964" checksum="282D8B624BADC303" modified="2023-09-13" version="1">MISIILFLLVLCVVIFVTRGYWLPKLEELRDRLRYSRLPFFRSEEDGSFEQNIEEGLTSSTFDLHQNLLDGDERHGVENADELRKIMKKYRCNFDQARLIHQQNKMKENGIDPRTGVPIDPKAVYFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2D3</accession>
    <name>A0A9P6T2D3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Histone H4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">HHF1_1</name>
        <name evidence="12" type="ORF">BGZ80_005560</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 10">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the histone H4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000274">
        <property type="protein sequence ID" value="KAG0019597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2D3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22912">
        <property type="entry name" value="HFD_H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000012">
        <property type="entry name" value="Histone H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001951">
        <property type="entry name" value="Histone_H4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004823">
        <property type="entry name" value="TAF_TATA-bd_Histone-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10484">
        <property type="entry name" value="HISTONE H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02969">
        <property type="entry name" value="TAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00623">
        <property type="entry name" value="HISTONEH4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00417">
        <property type="entry name" value="H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9 10" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TATA box binding protein associated factor (TAF) histone-like fold" evidence="11">
        <location>
            <begin position="62"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0019597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="102" mass="11266" checksum="276050BA3E3E236F" modified="2023-09-13" version="1">MSGRGKGGKGLGMAGPKRHRRIIRSIQGISKPSTRRLARRGGVKRISAYIYEESRCAARQFLGNVIRDAVTYTEHAKRKTVTSLDVVYALKLQGRTLYGFGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2D7</accession>
    <name>A0A9P6T2D7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Regulator of volume decrease after cellular swelling-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_005519</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the pICln (TC 1.A.47) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000272">
        <property type="protein sequence ID" value="KAG0019625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2D7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034709">
        <property type="term" value="C:methylosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034715">
        <property type="term" value="C:pICln-Sm protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006884">
        <property type="term" value="P:cell volume homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006821">
        <property type="term" value="P:chloride transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000387">
        <property type="term" value="P:spliceosomal snRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003521">
        <property type="entry name" value="ICln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039924">
        <property type="entry name" value="ICln/Lot5/Saf5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21399">
        <property type="entry name" value="CHLORIDE CONDUCTANCE REGULATORY PROTEIN ICLN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21399:SF0">
        <property type="entry name" value="METHYLOSOME SUBUNIT PICLN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03517">
        <property type="entry name" value="Voldacs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01348">
        <property type="entry name" value="ICLNCHANNEL"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="94"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="151"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="201"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="112"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="154"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="201"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="252"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="262"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="292"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0019625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="318" mass="34242" checksum="3BD4C7DBF3D92740" modified="2023-09-13" version="1">MTITIIHQAPSISDARIRYTQENITLHVTPASSLIQNPGTLYISDECLYFFSSGSHAGFAIQYPSIIIHAIARESRVGPSIYCQLEGSLASLGPAASSSNGHSGGNGASAGQDEEEEEEEDSILELSFAPADVSSLDTIYENLSYCASLHQDDEAGDMDEDDYYEDDENDHDGLYADADIQGGYIPKSSSATVIGVVAPSSSSAAGASSSSASALATGAGEGQVEQIPDIDLQSGEWYTGNPETDARFELSEQGQVNIKQWHQNENKGEEVQTGKRGRNEQDGQGDEDVETGENSQDQGQEYTEEQLQEARSKMWRAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2T2</accession>
    <name>A0A9P6T2T2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">60S ribosomal protein L30</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">RPL30</name>
        <name evidence="8" type="ORF">BGZ80_004186</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL30 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000216">
        <property type="protein sequence ID" value="KAG0020448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2T2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00202">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.30:FF:000001">
        <property type="entry name" value="60S ribosomal protein L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00481">
        <property type="entry name" value="Ribosomal_eL30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000231">
        <property type="entry name" value="Ribosomal_eL30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039109">
        <property type="entry name" value="Ribosomal_eL30-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022991">
        <property type="entry name" value="Ribosomal_eL30_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004038">
        <property type="entry name" value="Ribosomal_eL8/eL30/eS12/Gad45"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002172">
        <property type="entry name" value="PRK01018.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11449">
        <property type="entry name" value="RIBOSOMAL PROTEIN L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01248">
        <property type="entry name" value="Ribosomal_L7Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00344">
        <property type="entry name" value="GATA_ZN_FINGER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00709">
        <property type="entry name" value="RIBOSOMAL_L30E_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00993">
        <property type="entry name" value="RIBOSOMAL_L30E_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GATA-type" evidence="7">
        <location>
            <begin position="585"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="516"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="530"/>
            <end position="557"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0020448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="743" mass="81830" checksum="C098C5595873DCF7" modified="2023-09-13" version="1">MLPQPTATMDENIGNNVNGLHSTVEGHLKRKSHPSPAADSPGSPTITTEPKRPKTSEFNEDGSIQKSTEVTQIEFNDALANILHVVHNLDKHKITNTVAISVVNGEKVERSLQNIRTKLREAQYSSTAAFKDDISAICQQAIIDNAKDPEKHDHARKLLQLASDLISDKSHYTIRSHGKKVRSREESQTTVPERDYDNFALFQRSADGFVFTSRATAKDESLDSEVAKTTLIPTASSVNPPLLKDVNTRPRPASTLADQIKKKSTGVEFFPYAPFTSFAPFVDSSNAEMNAEDTSSAYEALLSRVEKRAKLSAAAVEEQRKSKAQLDSILEVAQQYQTQENGTGINVADLEFLSEEGLDVKNLLELANNAKSNNESLAPLEAIQRNATLLYELYKLQEERFASKDHTIGAREREIATILRNSLMEMAGQVTPSTFVTPEVIEDAIKRIPYKEAAFTGTLPTNKPFAFPINTTRSGLPPNATVYPTHNPVAHRKPAPPTTIIPQVVLSPHINMTGGYPSIPQPHHHHAYSIPQQPTHQKTYSRPRANTSNTPAPLQVSANGDVTFRKNFHTVVTSTGGTPAHWRRNDSQIPCANCGTLVSPIWRLGVRNEKLCNACGQYNKKWNGLHRPKYSAMAPINKKKVKTGEGINSRLALVMKSGKYQLGYKSTLKTLRQGKSKLVIISGNCPPLRKSEIEYYAMLSKTGVHHYTGTNVELGTACGKYFRVGVLSITDAGDSDIIAKTEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3E3</accession>
    <name>A0A9P6T3E3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">EamA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_001488</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000134">
        <property type="protein sequence ID" value="KAG0021894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3E3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3730.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039632">
        <property type="entry name" value="TMEM42"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31965">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31965:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="150"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="30"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0021894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="180" mass="18977" checksum="4D4920F18F189DE5" modified="2023-09-13" version="1">MSGHRPRKSSAAARKRAAASSSSVGSSAAIPTAILAGTFAALASVFAKLTLDARTIDFLRNACNTFLAPTTPYCTTMFIAKEGETSPIVVAVRSACFGLIFICNATMWTLFTKALNRSKSSATVTVINSAANFCLTAVLGYALFSEPLAMQWWFGASLIVLGSVLVSSNESSESSKKKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T421</accession>
    <name>A0A9P6T421_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Tyrosine-protein phosphatase non-receptor type 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">PTPN1</name>
        <name evidence="5" type="ORF">BGZ80_000913</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000120">
        <property type="protein sequence ID" value="KAG0022158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T421"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00047">
        <property type="entry name" value="PTPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050348">
        <property type="entry name" value="Protein-Tyr_Phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000242">
        <property type="entry name" value="PTP_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003595">
        <property type="entry name" value="Tyr_Pase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19134">
        <property type="entry name" value="RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19134:SF449">
        <property type="entry name" value="TYROSINE-PROTEIN PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00102">
        <property type="entry name" value="Y_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00700">
        <property type="entry name" value="PRTYPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00194">
        <property type="entry name" value="PTPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00404">
        <property type="entry name" value="PTPc_motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50055">
        <property type="entry name" value="TYR_PHOSPHATASE_PTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="3">
        <location>
            <begin position="38"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="4">
        <location>
            <begin position="236"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="303"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="309"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0022158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="324" mass="36642" checksum="C62BDEF031E7B6EE" modified="2023-09-13" version="1" fragment="single">MPFSSSSAATLTRLPGFLRQGSASARVDQQKQLFSNLDQQERQRVQAAYSPESPFSVAHAVQESTRNLNRYTDIVPYKHSQIHIYAGASTPVLYPLTFINANRITAPSSLRSSLPAEWRGYIATQAPLPQTQSRFWRMVSEQNVHVIVCLTAVSHDRSQRGQKAERYWPLAGETDEFDRDLHVRNLDKSDEEGKVVYRHFEIWNPIDTASERRQLLFVHYQGWPDHGVPSKTDDLRDILYKIRAWKSEQQRQPQQASHQKDFGPIVVHCSAGCGRTGTFCVIDTILSVLEKIRYPHLALSPSGFDPNDASVQAGEQSPQGQQGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T481</accession>
    <name>A0A9P6T481_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BGZ80_009404</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JAAAID010000056">
        <property type="protein sequence ID" value="KAG0023453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T481"/>
    <dbReference type="OrthoDB" id="68483at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14008">
        <property type="entry name" value="STKc_LKB1_CaMKK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000206">
        <property type="entry name" value="Serine/threonine-protein kinase Ssp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43895">
        <property type="entry name" value="CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43895:SF152">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE TOS3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="250"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="180"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="422"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="751"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="794"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="91"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="188"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="229"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="438"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="462"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="767"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="794"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="279"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0023453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="934" mass="102893" checksum="36F01D3593884656" modified="2023-09-13" version="1">MPQRQSQKPVGDSHGQLSIPWFKQTDLRSVRRGSSGAISNNSITDIEESTSDQDSFQETSSSPSDKSSRAASPSAASSSVTQLPSQKKGKTSGLRLSLKSLRSSKSHPQTVPDGNGSAHDQRTIVEAAPRSAFDRRLSYDQQSFEGRKSFENVDSKQWDPTSAALQFSTSAPKPASRFSFIYSPAPASPSTNRSSHQRNNTTPMQSPVPSNYGTSPGRSLASPSPQLVRETHTMKKEYDPMTGNKMINKYMVVRELGRGVHGKVKLCQDITTNEFCAIKIVDKTSRRRLGRSQLSNEQKIRREIAIMKKCIHPNVVRLIEVIDDPNARKIYLVLEYMEGGEVRWKDTEDKPILSLQDARSIFRDIVLGLEYLHMQGIIHRDIKPANLLLSAEKSVKISDFGVSHFSEKNALERDLEGSPIVSKGFNVQPTDGAPNHGSLASPVSSSFSAKAHATIGGGHQPENGSPFQPRQPSNITQHQQWGDDLELAKTAGSPAFFAPELCYTSEFPHAITPALSASQTSFTVPNPVHRSSFPNSSSTLGVTAGHGSVRPPITKAIDIWALGVTLYCFIYGRCPFTADTEFELFNIIPRREPSFPDNVPGREYVDPSLKELLSRLLEKDVYKRITLKEVKEHPWVTEDLQDPVRWRIETDPNNYQRVHVTEDEVKGAVTIMDKIKNRIRKLSVSIGNFTNHSPTTERSPIPIIRSPNSSLPAQSYMSNPASLPERFHNFHLYNGPPTSFVSGRLERPNSVCSNASSIDEVDEGDENSGQSGSGSSAQNNTSYVGRRRLFNTTGQQQHNQQPTAQYQHSGYQHRPPSFTGLSSLSGLSGFSGHPISIANAMPARRTYSDDQLDQAIGGRVGPLTHATPGGGRVVSMGHSGLSRSWVYSPTEVSPLSPVLSEQMEDQLQDMSQELTPRPLAQSIIAEERTYSPLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T4H5</accession>
    <name>A0A9P6T4H5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glutamine amidotransferase type-2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_004774</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000024">
        <property type="protein sequence ID" value="KAG0024260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T4H5"/>
    <dbReference type="OrthoDB" id="10252281at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004066">
        <property type="term" value="F:asparagine synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006529">
        <property type="term" value="P:asparagine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01991">
        <property type="entry name" value="Asn_synthase_B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001962">
        <property type="entry name" value="Asn_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051857">
        <property type="entry name" value="Asn_synthetase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45937">
        <property type="entry name" value="ASPARAGINE SYNTHETASE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45937:SF1">
        <property type="entry name" value="ASPARAGINE SYNTHETASE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00733">
        <property type="entry name" value="Asn_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0061">Asparagine biosynthesis</keyword>
    <keyword evidence="3" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="4">
        <location>
            <begin position="2"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0024260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="624" mass="69680" checksum="201A743C4B8FEFA6" modified="2023-09-13" version="1">MCGILFGIQKQDAKSCQVYEKTWSTLQELNARRGPSAQDIHKITIAGNEPRGAETDNSQLEFYGAVLHLRGDTVTRQPHVSKSGNVLIWNGEIFDGIFVDHHQNDGRVLMDQLEAISDQGEKEHTKAFLDIMAKIEGPYAFVYFHASSSKIYFGRDCLGRRSLLWHRTIKEGTEGEIASLPFILTSVGYSTFRSDLLALEEVPADGIYSLRLGSEGEKLIARYPWVSSISDQSNTTECEYSMKLPFGRVNDHIPTEDELSDLFPEDIKFDQAHPEIVPPVTDDMKKAISGMIAVLGDSVRRRVQDIPRTGLPHDARVGILFSGGLDCLCLAAMADRFLPEGEAIDLLNVGFENPRSVKAKAAEEALALKRQKRLGLAAANSSTGSQTSRAQDSKYNVPDRITGYESLAELKRIAPRRHWNFVEVNVPFEEATAQRSEILERIAPLETVMDLSIAMAFWFASRGIGYIKNEQNEMIPYTSQAKVLLSGLGADEQLGGYSRHKEQFKVASWGGLIHELQLDLDRISTRNLGRDDRIISDHGKEARYPFLGANVVQFLSSLRVDLKVDLRYPRGVGEKILLRHVARELGFTRASSHWKRAVQFGARTAKMTDSGRSEIGQQVVDRGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MDH3</accession>
    <name>A0A9P6MDH3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_008049</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004250">
        <property type="protein sequence ID" value="KAF9993735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MDH3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="42"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="208"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9993735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="312" mass="34277" checksum="E666800E8C58A0CB" modified="2023-09-13" version="1" fragment="single">MSTFAVTPSTQALAFTAAPSLSPSPPLSPSPLPRPVRALELPEILSLIGQYLSQRDALSCVLVSRTWHDSFQPVLWGHVETANEIPPEDIISHARYIRSLSLADLTGLEKVLENCTRLETLILWPDAFENEEDEEDEDDEMEDEDEENIVRDEAVSQANVLTLLSGGRENEPQGNGSSSNSGRTTELSQSPQPPPALHPVEQQGLRLDTTSSYRTGNTATKVRRDSGVGDDTVGVGHVHEGANWDSLMKNSSAITTIEENMELLDVQEQNPASALETPSFNQTKPQSQLTNLILRNQNITRVEVYVERKSPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MDX6</accession>
    <name>A0A9P6MDX6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">phosphopyruvate hydratase</fullName>
            <ecNumber evidence="4">4.2.1.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ENO1_2</name>
        <name evidence="10" type="ORF">BGZ80_007939</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(2R)-2-phosphoglycerate = phosphoenolpyruvate + H2O</text>
            <dbReference type="Rhea" id="RHEA:10164"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58289"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="4.2.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 4/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the enolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.11" evidence="4"/>
    <dbReference type="EMBL" id="JAAAID010004172">
        <property type="protein sequence ID" value="KAF9994036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MDX6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000015">
        <property type="term" value="C:phosphopyruvate hydratase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004634">
        <property type="term" value="F:phosphopyruvate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="entry name" value="Enolase-like C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000941">
        <property type="entry name" value="Enolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020810">
        <property type="entry name" value="Enolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020809">
        <property type="entry name" value="Enolase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11902">
        <property type="entry name" value="ENOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11902:SF1">
        <property type="entry name" value="ENOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00113">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00148">
        <property type="entry name" value="ENOLASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01192">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="Enolase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00164">
        <property type="entry name" value="ENOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enolase C-terminal TIM barrel" evidence="9">
        <location>
            <begin position="1"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9994036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="159" mass="17629" checksum="14F684C746ADB93B" modified="2023-09-13" version="1" fragment="single">LTSLYKEFIAHYPIVSIEDPFDQDDWAAWSHVSEQTDIQIVGDDLTVTNPLRIATAIDKKACNALLLKVNQIGTITESIKAAVLSQQSGWGVMVSHRSGETEDFTIADIVVGLRTGQIKTGAPCRSERLAKYNQLLRIEEELNGDSIYAGENFRKAHLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MEC7</accession>
    <name>A0A9P6MEC7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_007875</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004112">
        <property type="protein sequence ID" value="KAF9994271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MEC7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9994271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="56" mass="6155" checksum="EB1933E647EAED6F" modified="2023-09-13" version="1" fragment="single">PHPLAVKREAFSLLTDGLTHQQIANCFNMGQTTITSWAKKLPKNALLGVKRPKAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MEP1</accession>
    <name>A0A9P6MEP1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Rsp5p-dependent ubiquitination, sorting of cargo proteins at the multivesicular body</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">SSH4_2</name>
        <name evidence="7" type="ORF">BGZ80_007356</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003746">
        <property type="protein sequence ID" value="KAF9996058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MEP1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd12910">
        <property type="entry name" value="SPRY_SSH4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001870">
        <property type="entry name" value="B30.2/SPRY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043136">
        <property type="entry name" value="B30.2/SPRY_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003877">
        <property type="entry name" value="SPRY_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035780">
        <property type="entry name" value="SPRY_Ssh4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050618">
        <property type="entry name" value="Ubq-SigPath_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12864">
        <property type="entry name" value="RAN BINDING PROTEIN 9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00622">
        <property type="entry name" value="SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00449">
        <property type="entry name" value="SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50188">
        <property type="entry name" value="B302_SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="B30.2/SPRY" evidence="6">
        <location>
            <begin position="64"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="16"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="310"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="416"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="21"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="325"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="383"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9996058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="436" mass="47066" checksum="4A6AA30E82E8C151" modified="2023-09-13" version="1" fragment="single">LIITIATAIRSCGQKAGWLTGSSSPSSRNRGSGSSSGRDGRVRGRGQIHQVPDWEQDPDATEGRLAALSDTERQAYDAAQAFQIVHPPNSVPTDISLSQYLSIQEKGVSAWEFEASYDHQLFVHDRTELSFSTQVACVQTNLPLPKQQEVYYWEVKMFEKSPNTVVSVGVTTKPYPTNRLPGWNRHSVGYFSDNGRKYCNSPWSGYPYGPIYFEGDVIGCGYRPRNGTIFFTRNGKRIDEAFTGFGRMNLFPTVGATGPCVLHVNFGQSGFVFVEANVKKWGLAPASGSLAPPPAYGSELGSILLEASGSATSQSPLPSGRRPILQSSSSRTQIYQTGSGLRREDSFQGVGGASRDVQGGSSSSPVPITLANMSAPPPNYSSLDRHGHPRNDVHGIEDDRVSIASTDSDDSATLLLGDAQLNPNNPSNSDLEDDGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MFQ9</accession>
    <name>A0A9P6MFQ9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Carbohydrate esterase 4 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">D25_3</name>
        <name evidence="7" type="ORF">BGZ80_007078</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003564">
        <property type="protein sequence ID" value="KAF9997116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MFQ9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471">
        <property type="entry name" value="CHITIN DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471:SF2">
        <property type="entry name" value="CHITIN DEACETYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="NodB homology" evidence="6">
        <location>
            <begin position="20"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9997116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="212" mass="24299" checksum="3613A3483FD90AC6" modified="2023-09-13" version="1" fragment="single">PAPPSLYQPGQVLRRCTKPKSYAISFDDGPGQLTDELLDYLEEQQLQVTFFMNGDNWNCIYRPHSQRLLKRAYENKHQIAAHPWSHRDLESLSDKDIREEMTRIEQAFRQILGVVPRYMRPPYGGVGERVRRVLEEMGYIIVLWDVDQLSIVDVEFSSSPTRDTGHPHHDEDMLASTSKWAEAVRGVASAALDRDAMTLGGIYQEATPEWAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MHG2</accession>
    <name>A0A9P6MHG2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">UAA transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">DRP1_1</name>
        <name evidence="8" type="ORF">BGZ80_006412</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003166">
        <property type="protein sequence ID" value="KAG0000168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MHG2"/>
    <dbReference type="OrthoDB" id="10261634at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004853">
        <property type="entry name" value="Sugar_P_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03151">
        <property type="entry name" value="TPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="26"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="54"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="166"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="203"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="241"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="266"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="295"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="Sugar phosphate transporter" evidence="7">
        <location>
            <begin position="29"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0000168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="350" mass="38476" checksum="33061C9DFF382C77" modified="2023-09-13" version="1">MLGKDRPHPLQLSAGSAKPAKPDTSYSWLAMYFFLNLTLTIYNKAILSTFKFGFPWTLTGIHTLCSGIGAYIMARMGYFTPAQLGEQENMVMLMFSFLYTLNIAISNVSLHEVSVAFHQVVRAMTPVFTIAISVAFLSKKYTGMTYLSLVPLLVGVYMATKGDYSFTAMGFFLTVLGTVLAAIKTVVTNRIQVGRLQLHPLDLLLRMSPLAFVQTVIFSWMTGELESMVSWSKTDMSTSLVIALLVNGVIAFFLNYVSFTANKKTSALTMTVAANVKQVLSIVIAVTVFHTTIGFLNGLGIILTLIGGAFYSYVDLREKAKKARPATPANAPILSEKESEELMNIRISTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MJS8</accession>
    <name>A0A9P6MJS8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Mediator of RNA polymerase II transcription subunit 22</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">MED22</name>
        <name evidence="6" type="ORF">BGZ80_005600</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Mediator complex subunit 22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002757">
        <property type="protein sequence ID" value="KAG0004559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MJS8"/>
    <dbReference type="OrthoDB" id="203279at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009332">
        <property type="entry name" value="Med22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12434">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12434:SF6">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06179">
        <property type="entry name" value="Med22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0004559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="194" mass="20272" checksum="BD138F780ABF11E3" modified="2023-09-13" version="1">MTSRPMGIGGSAAGVPAPIIASGTIGTAPVITAGGAVPTAAVGGGAGVKSASLSALQEIEEAYNKRLDNDVAQLMESFGDIVKVASIAYNESSISKDKYKLAQESYQIQGRATNIVSSAESLLAMVTELKQTLLLNDANTLAQLSTQRQQELSTQKTAVKQRVLGLKEEVDRTIWELEQVCFGTSLAPTPSSQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MK23</accession>
    <name>A0A9P6MK23_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GTP cyclohydrolase II</fullName>
            <ecNumber evidence="3">3.5.4.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">RIB1_2</name>
        <name evidence="11" type="ORF">BGZ80_005382</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>GTP + 4 H2O = 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + formate + 2 phosphate + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:23704"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58614"/>
            <dbReference type="EC" id="3.5.4.25"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; riboflavin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GTP cyclohydrolase II family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.25" evidence="3"/>
    <dbReference type="EMBL" id="JAAAID010002658">
        <property type="protein sequence ID" value="KAG0005810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MK23"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003935">
        <property type="term" value="F:GTP cyclohydrolase II activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00641">
        <property type="entry name" value="GTP_cyclohydro2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10990">
        <property type="entry name" value="GTP cyclohydrolase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032677">
        <property type="entry name" value="GTP_cyclohydro_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000926">
        <property type="entry name" value="RibA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036144">
        <property type="entry name" value="RibA-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001591">
        <property type="entry name" value="PRK00393.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00505">
        <property type="entry name" value="ribA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21327">
        <property type="entry name" value="GTP CYCLOHYDROLASE II-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21327:SF29">
        <property type="entry name" value="GTP CYCLOHYDROLASE-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00925">
        <property type="entry name" value="GTP_cyclohydro2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142695">
        <property type="entry name" value="RibA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0686">Riboflavin biosynthesis</keyword>
    <feature type="domain" description="GTP cyclohydrolase II" evidence="10">
        <location>
            <begin position="252"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="68"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0005810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="463" mass="50857" checksum="B4FB35491FAB12F5" modified="2023-09-13" version="1">MASDISMNDAPVVVHSDYIPRNAIDHMNPFFFKSHHHAHSQYGHHHHHSHHNALRQQPYTTPTVVVAAAASHPHSHSIAKDFPSPSSGTDSSSSSSSSSPSSVDLQIPVPRHLSAHLDPCTAPSYNTPPATPPLTLLERQAAAAAAANANAASVVEAKRKNKDDPLAWCTARARIPTPDGSEYFLHIYENKMDKKEHLAFVFGDAIRSQSLDRVQPNETEMDRIKRGAYTGRLQNTVDLPTQQQESLAAPTSSTVTTTETLAAMDVDQNTTSSMVTPAPVAVPLVRIHSECFTGEIGHSARCDCGEQLDEAIRLMKAEGSGVVVYLRQEGRGIGLGEKLKAYNLQDLGYDTVMANLLLNHGADERTYEVAQAILEDLGLNQIRLLTNNPDKMEKIEKDSNIKVMDRVPMMPKSWEAIQQGTEAEFVVKEGAVENKIVKGKELDKYLKVKVERMRHLIPIPTSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MK61</accession>
    <name>A0A9P6MK61_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cysteinyl-tRNA synthetase class Ia DALR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_005492</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002702">
        <property type="protein sequence ID" value="KAG0005210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MK61"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004817">
        <property type="term" value="F:cysteine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006423">
        <property type="term" value="P:cysteinyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1910">
        <property type="entry name" value="Cysteine-tRNA ligase, C-terminal anti-codon recognition domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015273">
        <property type="entry name" value="Cys-tRNA-synt_Ia_DALR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024909">
        <property type="entry name" value="Cys-tRNA/MSH_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10890:SF3">
        <property type="entry name" value="CYSTEINE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10890">
        <property type="entry name" value="CYSTEINYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09190">
        <property type="entry name" value="DALR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cysteinyl-tRNA synthetase class Ia DALR" evidence="4">
        <location>
            <begin position="44"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="240"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="191"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="255"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF09190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0005210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="294" mass="32212" checksum="EEF2A4BA11F1B652" modified="2023-09-13" version="1" fragment="single">NFFANSKAMIAEAKHTALDSTGTHNFRRLELDMISALKERQNAVHAALCDSINTPNAMAELLALVSRTNVYIKDAGKNLNVEVVNKVAQYVSKTLRTFGLDGIVSDPIGFSGAEGGAAGVSVEDVAMPYLQVLSTFRDTIRSYAREGRSAQEMLALSDKLRDEDLERLGVSLDDREDGKALIKFIPAEELAAQRQAKIQQAAEKAAKKEEAARAKEAARLAKLEKGKVSHLEMFRQGASASEYGSFEDGTGIPLTDKDGQELPKSRKKKLTKEWEVQKKLHEDYLAEKAKGTIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MLP1</accession>
    <name>A0A9P6MLP1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004797</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002402">
        <property type="protein sequence ID" value="KAG0007335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MLP1"/>
    <dbReference type="OrthoDB" id="2399204at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="59"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0007335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="119" mass="13221" checksum="D6B1CAF9D93034D9" modified="2023-09-13" version="1">MSDQTPFTSVNEGSDHPKYRIGGFQTEVPNNQAALQGEFNLGTNPTSDSNANVNANEGPSETPSTTEPTADEKSEQDQEREQRERRFKELMDSGIINLNQKDAKPGRQYTLPVVKPKLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MLR3</accession>
    <name>A0A9P6MLR3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Sensitive to high expression protein 9, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">SHE9</name>
        <name evidence="12" type="ORF">BGZ80_005038</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Required for the maintenance of the structure of the mitochondrial inner membrane. Involved in mitochondrial morphology. Causes growth arrest when highly overexpressed.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homooligomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Mitochondrion inner membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the SHE9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002505">
        <property type="protein sequence ID" value="KAG0007096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MLR3"/>
    <dbReference type="OrthoDB" id="5595506at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007007">
        <property type="term" value="P:inner mitochondrial membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008839">
        <property type="entry name" value="MDM33_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31961">
        <property type="entry name" value="SENSITIVE TO HIGH EXPRESSION PROTEIN 9, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31961:SF3">
        <property type="entry name" value="SENSITIVE TO HIGH EXPRESSION PROTEIN 9, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05546">
        <property type="entry name" value="She9_MDM33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 10" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="2 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="441"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="645"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="58"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="139"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="494"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="63"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="84"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="139"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="182"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="200"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="232"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="498"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU364128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0007096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="667" mass="72858" checksum="7B42A7F948BF09BB" modified="2023-09-13" version="1">MATHLRLIRSTGSLARIQSHLPNTSLYTLRSHISYGRLVSYGPIGSTLINRGFSGTFAKRSNHPTDDSKGLKDTPGKNDAAQKTTEEEALNKASEEAERKRIEAQDAALKEILDSAAAEKRQIEQEMARVAEEKARQAAKRAAEEEARQAAKKAAEEEARRAAKESAEKQAKLQRSKSTNISNAESEATSASNSPGKVTKASNLKTGTTTASDVSKNNSQLLGSEASSTLNASQSSAAGATQSKNDSKEKASQAAPDESSAEPFTSKLLPYKRSIGASTEYIRSAIPDSIRQLTESVKRKDYRETISQLAEHLNSITGYNAINELKHKVIAHGDCLDEARIKLVQAKQAYEDAISTRSDTQKAINDLLQRKHLWSPNDVIRFTDLYRSEHANEQSEQKTKAAYKLAESDVESKSRMLTRVIMERYHEEQVWSDKIRAASTYGTWGLVGVNVMAFLIVQAFVEPRRRRKQVERYEELVQDLTERGILPERTSDLAVSGANATTPGTANGSVSTSSDAPIAVGGELLGGEDVLLKLMMSTEERLDRMETLLLQQSSGGTGKNFSKEVSIDVYGSPDGEYVLTEDGSIAFLQNDIVETTDMGESWGEGLSQGIRFEIRSDLTSNTTKDRLSLILRDGDAEVPATRRDFLVSSLGGALIGGLIAVAVMMNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MM06</accession>
    <name>A0A9P6MM06_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Canalicular multispecific organic anion transporter 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">ABCC2</name>
        <name evidence="13" type="ORF">BGZ80_004509</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002294">
        <property type="protein sequence ID" value="KAG0007560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MM06"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18603">
        <property type="entry name" value="ABC_6TM_MRP1_2_3_6_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000010">
        <property type="entry name" value="Multidrug resistance-associated ABC transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000997">
        <property type="entry name" value="Multidrug resistance-associated protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF443">
        <property type="entry name" value="MULTIDRUG-RESISTANCE LIKE PROTEIN 1, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="35"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="69"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="540"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="623"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="161"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="500"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="402"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="410"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="427"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="458"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0007560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="822" mass="92070" checksum="E33C188793DFB828" modified="2023-09-13" version="1" fragment="single">MIRTLNRREEPFRKKIDVLRANELKALKTLATIRSILTIVFSSVTLLMGLFTFWTYAYYGGPNMTPGKLNSEIIFVSIALFGIMNKPLGMITHTFSTAIATNVAMKRIQKFLLMEEIDPTVVCRYSRQSHLSIPGGNYKELLAVDIENGTFMWEKPADSVIQHTDAAMDGERQPLLATSASQPAKPILSDITLHIPEGNLTAIVGRIGQGKSSLLSAIMGEMYKDPEGSVKVYGDLAYVPQQAWIINATVRDNIIFGKPFDQAKYDHIIYAAGLRPDLEMLVAGDQTEIGERGINLSGGQKQRVSLARAAYQDADIYLLDDPLSAVDAHVDQHLWKHLIGPDGLLKDKTRILVTHGIHHLEHVDQIVVLKDGSISEEGGYDKLMKAHDAFYQLIKEYSIGQKKHSSTKQRIHDMLHGKKDKQEHSEGSCSPKTGNNSDSEGDGSERDTIIGEGDASSAKDSQSGNDNSGELITEEKMEFGRVGWDVVLIYARAVSYPYALICIFLFVLSQACHIGTNFWLRYWIFDTESREKNGYEPRPTSYYLIGYGELVILFMCLDIIVNYTSEVICGLRASKVIYDRLLTRILRMPMSFFDTTPMGRIVNRFSSDIDAIDTRLPEEWNDLFAFISIIGGTLLVIAYSTPIFLVAIPPLLLTYFWVQHYFIMSSSSLKRLSSTSRSPLYQHFSETLVGVSSIRAMKGLREQFIKQNEARADIIINRYHAYNLDNRWLQVRLETLGGITVFLASSLAVWNAGELDPSLVGLALSYALNMTGFITYLVRTVNAVQNLLVSVERVDEYSQKPVEAPVETGARLPPNWPAEGRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MM09</accession>
    <name>A0A9P6MM09_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Pyridoxal phosphate phosphatase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_005127</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002546">
        <property type="protein sequence ID" value="KAG0006817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MM09"/>
    <dbReference type="OrthoDB" id="10267182at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006384">
        <property type="entry name" value="HAD_hydro_PyrdxlP_Pase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016965">
        <property type="entry name" value="Pase_PHOSPHO-typ"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01489">
        <property type="entry name" value="DKMTPPase-SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01488">
        <property type="entry name" value="HAD-SF-IB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20889:SF12">
        <property type="entry name" value="LP01149P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20889">
        <property type="entry name" value="PHOSPHATASE, ORPHAN 1, 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06888">
        <property type="entry name" value="Put_Phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF031051">
        <property type="entry name" value="PyrdxlP_Pase_PHOSPHO2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="18"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="20"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="20"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR031051-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR031051-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR031051-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0006817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="286" mass="32312" checksum="ABF34CB53706445E" modified="2023-09-13" version="1">MLSSTTSKAPAKRLFVFDFDWTLIETDSDNWVFEHLCEELYQVQLEAVGKVQWTDLQQRLLGGLFERGISREDIERTLSHIPFAPEMIEALKLMKSQGSELYILSDANTVYIETVLRAYNIDHLFTEVITNPAKFDERGRLNVVRFHGLDKEPHRCPLPCQPNLCKGREIQKLIDSQSWDQVVYMGDSTNDFCPSTRLQSKDVVLARCSLLLEKEIKENPQMVKANVVYWDNARDVLQATKAILGASSSSSSSAASNKSASRTKIPEVLSVMESSDSKIYAQAVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MM43</accession>
    <name>A0A9P6MM43_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005001</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002495">
        <property type="protein sequence ID" value="KAG0007152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MM43"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040364644" evidence="1">
        <location>
            <begin position="29"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0007152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="78" mass="8598" checksum="C01F4CCDBE1F54ED" modified="2023-09-13" version="1" fragment="single">MMNPKSSRFALFAVFLVVAGLLPNDSLALKSTGVQRLAKDISPITGWDDQEYPRVAAAPKEKRASKALHEWSNWAGNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MM46</accession>
    <name>A0A9P6MM46_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004884</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002443">
        <property type="protein sequence ID" value="KAG0007262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MM46"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="157"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0007262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="200" mass="22823" checksum="33FD1FC1A2FA15B4" modified="2023-09-13" version="1" fragment="single">MNLHVGSSMHQTLVFLIPRKNIDPLDIIESIFENFGPVDGFHHNPIPSGSKLELYFANAETYQAKTKYRHVPVNFKTEDFQKVFGTYGVILEIGRYYWQINDKRILSGDGFIFFEQSQRKYPPLPEFIDLGAGVIHTKITTAPIGVPITISVQHTNQPTSSQPQPQTQAHIKTNVKKKRNSKKRLKNNSREHSHPADSNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMX7</accession>
    <name>A0A9P6MMX7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cyclin-dependent kinases regulatory subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">CKS1</name>
        <name evidence="6" type="ORF">BGZ80_003662</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the CKS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001989">
        <property type="protein sequence ID" value="KAG0008235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMX7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.170.10">
        <property type="entry name" value="Cyclin-dependent kinase, regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000789">
        <property type="entry name" value="Cyclin-dep_kinase_reg-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036858">
        <property type="entry name" value="Cyclin-dep_kinase_reg-sub_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23415">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT/60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01111">
        <property type="entry name" value="CKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01084">
        <property type="entry name" value="CKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55637">
        <property type="entry name" value="Cell cycle regulatory proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 4" id="KW-0132">Cell division</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="56"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="106"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="183"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="225"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="184"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="228"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="315"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="325"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU311113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0008235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="451" mass="53117" checksum="267E02C562C491E8" modified="2023-09-13" version="1" fragment="single">MTRASRIEAQIYEDQEEPLDHLAPTHHTLQQGHLERYSEGGQYEYEEEGYEVIDKENQPIRHQEAIPMSHQHRAHLQQQYQYRQQHFPQQQEQHPGDMSGIELAQDSASDTEEIPQQHQYQDSHRRRPQDSGAIFYEGQDEHDLENVSDQENVQPSSHVAVEAVSQAPTQALDARQQLLYRNKQVSQQQGTQYHQHHHQRQALKAEPQEHVGEVYISREQQLQEFQRSRTQLSRQQSTTQKHQQQQQQQQQQQQQPHRKQAMQEPPGAPTRKKVRMTAEELADAKAGQVWDEGTDADGAVTAVGPSRDHEEQQVRPHHHNHHHSQQPQQQQQQQQQKQQEGHQQNQSQAQQQPRVPEDPAERKKRKMREWQKFFAEKITYGDIYEDHVHEFRHVILPKNMLPFISSSLKEQPGTNNHTLKLLTEDEWRSIGVMMSQGWENYMRHDPEPHVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMZ2</accession>
    <name>A0A9P6MMZ2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004318</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002210">
        <property type="protein sequence ID" value="KAG0007729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMZ2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0007729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="178" mass="19866" checksum="652FB475E5ABD251" modified="2023-09-13" version="1">MANIQALKQRNIKSDSDSKTLPKGAVFQGGDFKYGAPPTKVHSAFSPVKTILRAWATLVGFLVLIVLITYQLHYTLPTPVNEPLNAVSGQAQFSEANVRKVVRHLSEDIGYRVVGTEQELEAKEYLIKELSQLKEDARIGSLRQSATTTDLDQAWPNFDMWIQVGDGSHRFDFMSKGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MP18</accession>
    <name>A0A9P6MP18_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Carboxylesterase type B domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003596</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001961">
        <property type="protein sequence ID" value="KAG0008312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MP18"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carboxylesterase type B" evidence="1">
        <location>
            <begin position="4"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0008312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="575" mass="64128" checksum="F471AB316E0C280F" modified="2023-09-13" version="1">MSASPIVNVPGCGTLQGVQAEDQPVVAKFLNVPYATVPERWRPAVKVVPWNGIRDASVQGPVCPQPESPNVLVSMTATNVDEDDEEAYSKVYSEEHCLNLNIFAPLNQLEKRSRPLIPVMVWIHGGSFKDGSNAMELYDGTNMVAHSIKGLGRPVIVVTINYRLNYFGFLSSSELVQDIQSDKRLSSNNHEKSVGNWGLLDQKIALEWVRDNIEAFGGDPKDVTAFGESAGAASIGYHISIPAHHGLFQRAIMQSGTATTMTAGYAQLEGQRRFNQLCQHFELNKPEISAAQKIEMLRKIPAKDLVKAGGKNVGMFIPTIDNVLIKGDVREWSHDPSRYDPGLKSAMVGDCRDEGTMFVPELGASSLKKWPRFKARYCPPGEEKEFEAIYGEPKTNAEAASISAVVLSDVVFLYPIHATSLALAHSREMNQSKEPLQIARYHFDRPLKIVDDMNLGLGAHHAVELPFVFGPGMYLDMLSEEEKALSRRVMETWILFAWGEVTRQHDLKHGLASLLPADAGVKSKEALVFTEECTVEKTLVERLDTRTLSFWRRSEAWVKRRLEERSRDRSQQARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPE1</accession>
    <name>A0A9P6MPE1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">ADP/ATP translocase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">ADP,ATP carrier protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BGZ80_002552</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">ADP:ATP antiporter that mediates import of ADP into the mitochondrial matrix for ATP synthesis, and export of ATP out to fuel the cell. Cycles between the cytoplasmic-open state (c-state) and the matrix-open state (m-state): operates by the alternating access mechanism with a single substrate-binding site intermittently exposed to either the cytosolic (c-state) or matrix (m-state) side of the inner mitochondrial membrane.</text>
    </comment>
    <comment type="function">
        <text evidence="16">Catalyzes the exchange of ADP and ATP across the membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ADP(in) + ATP(out) = ADP(out) + ATP(in)</text>
            <dbReference type="Rhea" id="RHEA:34999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:35000"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="3 16">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="16">Membrane</location>
            <topology evidence="16">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001633">
        <property type="protein sequence ID" value="KAG0009285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPE1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005471">
        <property type="term" value="F:ATP:ADP antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140021">
        <property type="term" value="P:mitochondrial ADP transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990544">
        <property type="term" value="P:mitochondrial ATP transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002113">
        <property type="entry name" value="ADT_euk_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45635">
        <property type="entry name" value="ADP,ATP CARRIER PROTEIN 1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45635:SF14">
        <property type="entry name" value="ADP_ATP TRANSLOCASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0050">Antiport</keyword>
    <keyword evidence="11 14 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 14 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 15" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="322"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="14">
        <location>
            <begin position="319"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="54"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="66"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="96"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00045250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU368008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAG0009285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="398" mass="42912" checksum="F8319BB591014F5F" modified="2023-09-13" version="1">MPATCPHRLGLGFGLAGPLVLNVVTAPAERVKLLLQTQDEIILNLREESLAAHHNHSHNHNHSHNDNNQNDHQSNHPSSEPLHDSVKGYNVNSGSEGEEKEEEEEEEPRSIIVPYAQLPYKDMQDCAEPWILGAAVEGTAVSSVALLAVYPLAVLQTKMAVDVVRRTRSVKKVPSVAPVASAATVAAAAAPAPTVTADSRDSVEWVEHNDGEYGSQESLPVAEATTPETLLSLSSSSSSSPSSVQEYEYTLSYKYRNACETFKAILESSEGYLGLYKGFSTVVISTFASRIGFLTLYRTLSPLLLNRSCPGLGSTSSSSRGLGAFLLVFGATSVVNLIVYPLSTVCHRRMVAAPGRYSSSWDAGKQIVEKQGWKALYKGVEVAMVRSAVMAVLSGMFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPU2</accession>
    <name>A0A9P6MPU2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_002920</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001748">
        <property type="protein sequence ID" value="KAG0008909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPU2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="101"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0008909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="113" mass="11934" checksum="10C65AD7AE5A45A9" modified="2023-09-13" version="1">MTDSDFEDADFDINDISSILKDIDSANLALDSIDVRADKLTASIMSLLKAQSLPNPYANIEPEPLEDEVSVLSVESVTITSEITLDAPSPSTLSKEDSAASEKSSSNSSSPAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQB7</accession>
    <name>A0A9P6MQB7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_002477</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001612">
        <property type="protein sequence ID" value="KAG0009357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQB7"/>
    <dbReference type="OrthoDB" id="552049at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026894">
        <property type="entry name" value="DnaJ_X"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44924">
        <property type="entry name" value="DNAJ SUBFAMILY A MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44924:SF1">
        <property type="entry name" value="DNAJ SUBFAMILY A MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14308">
        <property type="entry name" value="DnaJ-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="97"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0009357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="432" mass="47564" checksum="437C5A24604D38ED" modified="2023-09-13" version="1">MGPTIIESRKPQYLTAECISCNTPVEFLMPKNSGEVIYIECYACKQVLSIDVQYPQKGTATAGSSSPNSSSSKRDSTSPSKPKRTGAGTDASPLETELYDILGVPVDATPAQIKKNYRALALQNHPDKNPDPESHAKFQKISEAYQILSDPKLRSDYNKYGQNKDVSPEGGFVNPEAFFKQQFGGDRFVDIIGEISIGRDMRDALNEPEDESLANLSPEEKAKREATASETKDKARDEARQARVDKLVQNLVHKLSIYTDGPCDYTAAKGYQEMIRLEAEELKEESYGVELLHAIGFTYTLKAKQYLGKQEMLGLGSWFHGVREKGHILSETVSTLRAAMDLQQSFTQLQEAEKAEMDETAKKALEEAAASKGLRALWKGSKLEVEGVLRDVCDKVLGDAAVPKATLIKRASALKIIGEVYEGVKADKPTTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQV9</accession>
    <name>A0A9P6MQV9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_002125</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001514">
        <property type="protein sequence ID" value="KAG0009730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQV9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0009730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="351" mass="40027" checksum="A470031674B07403" modified="2023-09-13" version="1" fragment="single">SCFWTNVPQLCKLKHLHRIELYDIYHGIDVDAVVDFLKMHDRIYNSIREIKVGGPDDLGRSSHPDVIQIIQSLKTIKVLDMTEWREALKHMDQIPTKHLETLLLGNVRMTTLQNTEPSALPSSDSEGDSNELLGGEEENQLRPEIQALQRCRLLRELRMPVLIEGLFEWAVHERRQKAEAPPSSSSIPYVSPLTKTAPYWDHGRDPLAQLENVHLSGTVTGPLISTLTHVVDAFRDSIQVLQSNSWVDSTETLTFCLNLSWTWCLPQLQVLDLQGEIAHRFRIQSLQHCPLLRILRLTLLHYVTPASSVELADPKVSKAWQSELETTLEDRDMYMGLMGSCVESPPEILYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRP9</accession>
    <name>A0A9P6MRP9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fcf2 pre-rRNA processing C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_000964</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001211">
        <property type="protein sequence ID" value="KAG0011084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRP9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039883">
        <property type="entry name" value="Fcf2/DNTTIP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014810">
        <property type="entry name" value="Fcf2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21686">
        <property type="entry name" value="DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21686:SF12">
        <property type="entry name" value="DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08698">
        <property type="entry name" value="Fcf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fcf2 pre-rRNA processing C-terminal" evidence="4">
        <location>
            <begin position="322"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="103"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="425"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="113"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="142"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="155"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="166"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="180"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="208"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="432"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0011084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="449" mass="51384" checksum="23C79FF7E04611AD" modified="2023-09-13" version="1">MKRESLELSQREQVGFEHLTQGSMDKVNIVKQDFKAFVEERLNTPEDNKIEINEYLSGYQVDHPRFNRRHVLTEAAIVIGYELMVPAYSLFAEVDGCKNGLASPPPLEIPLPKARRARQSKPKAKIPLEEEESETVESSSPTPTPDSKSPPPESNNLLDGSYTRQQQHDHQLEGAHSTDDESEKDGENMDEAEESSDEEHDNDKVTEEEKEEEGEKSDDDDDDYLDHLIIKAQESLKRKAMFEENSDEPRFNFPKLETGLDTNSTYIKQQGTRAKVDMNSVIIVEKGNTGSKSNVQSALEACEINMNAQKVHISKKQKKEEKEKTAGKGWFDLPQQILTPELKRDLQILKLRNVLDPKRFYKREEKGKAKFPKYFQVGTIIEGNTEFYSSRLTKKERATTITGEVMKDLTGRDYYKRKFNEIQESKQSGGKRFNKKGKGKQSKSWRAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRU9</accession>
    <name>A0A9P6MRU9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Homeobox domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_001005</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001220">
        <property type="protein sequence ID" value="KAG0011038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRU9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017970">
        <property type="entry name" value="Homeobox_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00027">
        <property type="entry name" value="HOMEOBOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 4 5" id="KW-0371">Homeobox</keyword>
    <keyword evidence="3 4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="7">
        <location>
            <begin position="667"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="4">
        <location>
            <begin position="669"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="380"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="427"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="520"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="577"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="730"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="827"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="49"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="87"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="112"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="136"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="173"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="185"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="206"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="224"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="257"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="384"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="439"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="522"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="542"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="593"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="608"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="642"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="831"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="842"/>
            <end position="854"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0011038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="863" mass="95083" checksum="FBEF13E741373D89" modified="2023-09-13" version="1">MHSNGHHRTDFNSQAQQQQHQRELRAITEEVDDPEDRPSHLPHLHQNHHSSYNNNNGNSNGNGAVVGRDGHYGNGNGVYSSPPSSSHGHEHSPLAESTREPSYTHRPIDTVSSSTAPPSSSFRPSHSDRYPNSNLSSRPASFSAVSSVSASAPSSSAPSSSSYSTAPRSAHSAPQNRSASWNTDRYQDYGHSYEEHHQRTDHSKSNHALHQQNYGPYTGPSSPPSSSSDAVFPSSSSSVSTKAPATETSAPLYYNQPPTSSSSPSSAAYSYSASNERGGHTSNRSSSSSARPMHEYAHAPTAEPSSSEQHRRQNHGPILPPPSALLSGAIENKPTRIYGRDSTVDDNWTPISRPTRVVPIDAPNEAWNYKYNSSSGMLPPPYPSSSTSTLPPPSSSSSSSSSLLAYSSNYSTAPVEQKRRVYGIDAADIPQRLPPPTPSSSYGSSQYSKPQQDTQDDLEEASRRRPVGQDSGNYPRHYVSSMASAYGSQAYGYSAPSSRHYADTDRNRYDYDNRGWKATQTSHSHVSSASSSSSFAPPRPYSQPQSQPQSQPQSPPMPMEIKPPIWYQNYAHNVPAKTQHQDSHYYHRHGHHQQSGGYSSSGYPTDQAPHDYEYRDEKGDKHSKSILNQPVHPFDTAEHKSSKSKKPKRIKNPGHDEDLIVMDDEFYAVKAKRKRANASQLSVLNAAFERSYFPSTEERLRLSKQCRMCPRTVQIWFQNKRQSVKARTEAMEAAATVSGASGLDERRDSNEDGSNDGQKRTIDDDGNESGDGLVDTGSRRHNSGSGGSNRRSDPNTMTPSEAVMSALHIQLDGRSVDYFSRKRRATIAKMEQNEKQQKQRQQEQAQPLQGQKQQAAERKMDES</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MS70</accession>
    <name>A0A9P6MS70_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">MSP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_000947</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001209">
        <property type="protein sequence ID" value="KAG0011094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MS70"/>
    <dbReference type="OrthoDB" id="75724at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090158">
        <property type="term" value="P:endoplasmic reticulum membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061817">
        <property type="term" value="P:endoplasmic reticulum-plasma membrane tethering"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000535">
        <property type="entry name" value="MSP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008962">
        <property type="entry name" value="PapD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016763">
        <property type="entry name" value="VAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10809:SF6">
        <property type="entry name" value="AT11025P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10809">
        <property type="entry name" value="VESICLE-ASSOCIATED MEMBRANE PROTEIN-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00635">
        <property type="entry name" value="Motile_Sperm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49354">
        <property type="entry name" value="PapD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50202">
        <property type="entry name" value="MSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="326"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="MSP" evidence="8">
        <location>
            <begin position="23"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="147"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="198"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="150"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="168"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="209"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0011094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="433" mass="47178" checksum="A19C98058F13793E" modified="2023-09-13" version="1">MTTVQSQQTQQSQIPTGATSNGLLQISPQQFQFTASRVAPGQVSKVKLKNLSSTPVGFKFKTNAPTKYSVKPVLGVVSPGETVKVFVRSDGWINPQDKFLLQTISLNEDEGKALDPPSWKAFDPKRFIESYIPCSSVSALTIRDHEDDSGAISSSSASSPPFHAYDANRSSGSLQRSPARQQQVFERWQHSEATRPTISIGGLGRRRSSASSTCSSINTSPSTYPTLFTPTTKTFDQLPSPMATAPTTPTSPTTFSSYTSKRNSLTSNFHGSIITSTIKEEPSGVGDSSPSEPTQYLLSALGLTEKPVLSTTSKFKILRRRNRKQLLLLSLMCLICLVFGILLPYDRVLEFLGVNVGAHKDWVSKDSDGKRVMEAEVQEDIGVLTTPIMGAVDYAETVDPYRANIHHASDVMAELNDIKIHTTRQSVVVEGAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTA8</accession>
    <name>A0A9P6MTA8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Velvet domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_011421</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000917">
        <property type="protein sequence ID" value="KAG0012914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTA8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.3960">
        <property type="entry name" value="Velvet domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021740">
        <property type="entry name" value="Velvet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037525">
        <property type="entry name" value="Velvet_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038491">
        <property type="entry name" value="Velvet_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33572">
        <property type="entry name" value="SPORE DEVELOPMENT REGULATOR VOSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33572:SF3">
        <property type="entry name" value="VELVET COMPLEX SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11754">
        <property type="entry name" value="Velvet"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51821">
        <property type="entry name" value="VELVET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Velvet" evidence="6">
        <location>
            <begin position="24"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="136"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="140"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="150"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0012914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="271" mass="30150" checksum="D73A0ED64D01BCAB" modified="2023-09-13" version="1">MGKSDKYYYQSKASEDDDDLDVDPNELIYSLEIVQQPLRARMCGFGDKDRRNVTPAPVLKLVAKMQDGKIVSASHLSKQAFVVTADLWLEDEVTERNLVLISSIPSSRTAAYSLQQATLAQESQLVVDQLGIHEHTPEGSSSYLSTTSSPVTAESSSNASRMSIRNVIHDVGVGSAEDADTHEEQEYHQDNDTYVEQDLRELRELSAATSQARMEMSTRNLVGQIAVSGQVAPGLDDEISHIWFAFSILSIRTEGFFKIRFCLTDLMRIPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTF2</accession>
    <name>A0A9P6MTF2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Arm-like repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_011477</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000927">
        <property type="protein sequence ID" value="KAG0012837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTF2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056251">
        <property type="entry name" value="Arm_rpt_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23948">
        <property type="entry name" value="ARM_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arm-like repeat" evidence="1">
        <location>
            <begin position="229"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF23948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0012837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="391" mass="43315" checksum="17969E6EDC8EF8BF" modified="2023-09-13" version="1">MLRNIFSSSSSGLPLKDVIDLANRHLEDARGADTSVKALFLCGNAKVMIKDAENIINKSVKGQTFNDDIAHAYHEHGKLLKELGQRSKAQKSYSKAEKWGYLHVTSRYSDPSKPTELNTSIAGSFIPSAALSATPTIAVAVLHANLNTTPPIIQDGVSTKSKDQIPTGSTTMTPLSIFVRDVAPFVAKIDMPETGARITSTPQLTYCISLLGYSLESKEGLNGFESDWLQATEGDPDEQRRLRSMAVDVIRAFVRDELKTSDVVSEAVSLATVLEREEFQKLLRVFVDGINQSLLLEIHLLEGLAYLMKNSPSENFNVDDLVKILELLSIRLKGTHQQSTQHTYQLATAVSRVLDSMVDSQVKDIEREQLHEPLSQYLKELQQSSDPRLVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTU1</accession>
    <name>A0A9P6MTU1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Acyl-CoA binding domain-containing protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ACBD6</name>
        <name evidence="6" type="ORF">BGZ80_011286</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000892">
        <property type="protein sequence ID" value="KAG0013102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTU1"/>
    <dbReference type="OrthoDB" id="539213at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000062">
        <property type="term" value="F:fatty-acyl-CoA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000582">
        <property type="entry name" value="Acyl-CoA-binding_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035984">
        <property type="entry name" value="Acyl-CoA-binding_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014352">
        <property type="entry name" value="FERM/acyl-CoA-bd_prot_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24119">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24119:SF0">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00887">
        <property type="entry name" value="ACBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47027">
        <property type="entry name" value="Acyl-CoA binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51228">
        <property type="entry name" value="ACB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ACB" evidence="5">
        <location>
            <begin position="2"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="260"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0013102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="303" mass="32657" checksum="F866E05B203121E6" modified="2023-09-13" version="1">MLEDRFKNAAAYMASKKNLNLPSSTKLALYADYKIATEGQCTQPRPSLIEFEKSAKWKAWKETGDRYIKELDAAKNSSASSDLQDIAQLTLSTKAMISYVQRVEDGQWGWTFDAADSTANSGGSIPTTGDQDLDELEAYLGVDKDEISAEELLARPYVPIQGQMEGAAMTASGISTLASPTEDDAEDDPFASAKGGSLKSLQAALAANPDIASLKDDMASSSHDSPGFTMLHWVCDRGSLEKAKLLVETYNVNVNAQDTEGSTPLHYACLSGWPQIVAYLKSVPGIDLTIKDNSGMTADECLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTV4</accession>
    <name>A0A9P6MTV4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_011266</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="9">The histidine box domains are involved in binding the catalytic metal ions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the fatty acid desaturase type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000887">
        <property type="protein sequence ID" value="KAG0013136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTV4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016717">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015876">
        <property type="entry name" value="Acyl-CoA_DS"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00075">
        <property type="entry name" value="FACDDSATRASE"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="9" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0013136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="93" mass="10541" checksum="D7974EA1BCAA0AC2" modified="2023-09-13" version="1">MATPLPPNFVVPATQTETRRDPLKHGELPPLFPEKITVFNIWKYLDYKHVIGLGLTPLVALYGILTTEMQTKTLIWSTIYYYLTGLGITAGKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MV00</accession>
    <name>A0A9P6MV00_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_011188</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000870">
        <property type="protein sequence ID" value="KAG0013268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MV00"/>
    <dbReference type="OrthoDB" id="75169at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.10">
        <property type="entry name" value="Diaminopimelate Epimerase, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003719">
        <property type="entry name" value="Phenazine_PhzF-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00654">
        <property type="entry name" value="PhzF_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13774:SF32">
        <property type="entry name" value="ANTISENSE-ENHANCING SEQUENCE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13774">
        <property type="entry name" value="PHENAZINE BIOSYNTHESIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02567">
        <property type="entry name" value="PhzC-PhzF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016184">
        <property type="entry name" value="PhzC_PhzF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54506">
        <property type="entry name" value="Diaminopimelate epimerase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="1">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR016184-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0013268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="302" mass="33139" checksum="DD2A349590C1956E" modified="2023-09-13" version="1">MSTATYPFFQVDVFTDKGYLGNPLAVVVALDPSLPVPTDQQMAQFANWTNLSETTFLLPPTDPSKADYRVRIFTPTCELPFAGHPTLGTCRVFLERIGAALNEPRKIVQECGVGLVELLMSQDGSIAFVAPPLSKTGVVEEDKVLIACQAMRIDRTEVLATQWIVNGPKWFALLLKDSETVLRANRTPTEQSKTIEFGIIGAYPEQQRKNPQDPLFEVRTFPHADTIDEDPVTGSFNAGMAQWLIGAGIAPPSYVASQGTAMGRKGRIVVRRDDTDGSISEKDRKIWVGGHSVICIRGTVQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MV19</accession>
    <name>A0A9P6MV19_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Translocon subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">SEC61_3</name>
        <name evidence="11" type="ORF">BGZ80_010802</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the SecY/SEC61-alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000793">
        <property type="protein sequence ID" value="KAG0013857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MV19"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3370.10">
        <property type="entry name" value="SecY subunit domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002208">
        <property type="entry name" value="SecY/SEC61-alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030659">
        <property type="entry name" value="SecY_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023201">
        <property type="entry name" value="SecY_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00967">
        <property type="entry name" value="3a0501s007"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10906">
        <property type="entry name" value="SECY/SEC61-ALPHA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00344">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103491">
        <property type="entry name" value="Preprotein translocase SecY subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00756">
        <property type="entry name" value="SECY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="31"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="130"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="302"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="326"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0013857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="361" mass="39425" checksum="81B4986141341A6D" modified="2023-09-13" version="1">MFFNPVFAVIIAFGQATVSVMNGLYGPPSELGAGICLLLILQLVVAGVIVVLLDELLQKGYGLGSGISLFIATNVCETILWKALSPTTYNFGNGPEFEGALIALFHLLFTRSNKTRALKEAFYRDNLPNVMSLLATALVFGIVIYLQGFRVELPVKSSRFRGQRGTYPIKLFYTSNMPIMLQSALTSNMFMISQMVYSRFPENILVRIFGTWAPYQGTNQMIASGGLAYYMSPPHSISEALLDPIHTVVYVTFMLTACALLSKTWIEVSGSSARDVAKQLKDQNMVMAGHRDASMYKELKRVIPTAAAFGGAVLGAVSVFADLIGAIGSGTGILLCITIIYQYWEMFVKESMENSGDALAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MV36</accession>
    <name>A0A9P6MV36_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_010395</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000719">
        <property type="protein sequence ID" value="KAG0014516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MV36"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF191">
        <property type="entry name" value="VACUOLAR BASIC AMINO ACID TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="83"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="152"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="86"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0014516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="192" mass="20651" checksum="CE1B5625AEB2CDC4" modified="2023-09-13" version="1" fragment="single">MDSKGKAPSINSRSDNDTVVIDTEKSQYNQPSQKEEYDEGKMEEIIVDENKLEIDESDVSSNKGHGNIDPGSDAHVTLPFKELMVVFVGLMLGIFLSSLDQTIVSVITTKIANEFQGLTEIPWIGTSYLLTSTTFQPLYGKASDIFGRKATFLFAVGIFLIGSALCGAAQSMIMIIVARGIAGIGAGGIMSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MV66</accession>
    <name>A0A9P6MV66_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_010554</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000746">
        <property type="protein sequence ID" value="KAG0014255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="391"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="493"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="652"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="710"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="840"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="906"/>
            <end position="987"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1053"/>
            <end position="1083"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1098"/>
            <end position="1122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1171"/>
            <end position="1200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1218"/>
            <end position="1310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="63"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="395"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="437"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="551"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="583"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="658"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="720"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="753"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="778"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="840"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="862"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="919"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="967"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1053"/>
            <end position="1066"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1176"/>
            <end position="1189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1223"/>
            <end position="1235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1236"/>
            <end position="1249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1261"/>
            <end position="1290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0014255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1310" mass="140536" checksum="ED3E8F176174E04E" modified="2023-09-13" version="1">MSYNVKFYWGLNIIYILQGAQFAFRPIVQAVDLGLRATISPVFFLPAPPFLIRFYRQHIKQNGHGSNSLNGGSKYGGPCRRNGSYTTETNVHQGSFTTMEEPHVLNSPPYSPGGSRTGRFEETGSGGASFDSETNRPNDREVTDKNKNRRIESIGSAYNPLRFFPSRDRGPSMESRKVFNQEFDQDDNTDGQHGPEDISRLNSFEYPNSDRNLSPRFNGPSIMEVQKPGVALTASGLKELERWSNNMRGDSSNANVEKLEMTNQISPPKANLESSPITGTTGWEVGGWGHVRQNSDGNENSLSSPMDPYLSNPTQLVQPLQATQNPEPDSEKPIELTTVVNIHDNEKDKVAPVPDSMIQGLTGLQRQLAEHRSALLPMVLAMQELDDCQGSVTYDSHDESSLGRDNADSNEPRKHRPRGVPNRRYDDTIITGMRPTYSEQSLNQNSESTTAGKPNTEEKSIGNGANTMHWSNYPANKSVISIHGTDDSYSAYYSASGSSKGTEKSAPGFKMKWLPGRKADEGDQVPSKKLGADPSSVAVNSVADESKISKRSSINANSSDGALATKGGKSKEPRRGVFSKVLGGDRGRSSQDINDQERDSKLLDSEGKPVTNAHGSPAPATVEALALESTIGLDAIDDEKGLQYYYPDPYSTLAEFKSPQSSTRDQATTQDVGLSRNTSVSRHPLSTIYSDVESINDVEGILTDMTVLGKVRSDDSQGNSSLKTPTKTSKSSKKSPKKDGMSLPSLDSSIADNYNNGSNITTSTSTSNSAPPSAGTSPQTSLPFGSLLSRSPSGSKRFAKSKSGRSKSDATPTRDSAEFPMQTEVTVDIMPIPVARNSSISNTATIRQPAQTSLSPPPRQSWARSKSFQGPTPTTAAALLSSKQSTGNFSIDTKLANELGVSVATGTPTSDIDPASAGVRTSLSSSIGSPTTASMSPHLSPTLEAMEHEENESSTVYTPSSPPMFPLPGLTSTGTSSLTRPGNYKPRIPVEYRANSLDRDSDVYGLPGGTGLNSKTGFSTAAMDMRRANNRHQRSVDNLSSSYYYRRAAEFSGNNNIGQRKPTSGLNRERERENEYSSSSASQQRTIDYYGIGIATDIEEGSRRKDPSSQSTSGNGARTLHKSKSSLDYSFAGVAIPGVANDSSRTSSLTSSQRIMADDTWTKAMVARAQNGGSGTTCSAGGSNSTRSSSPPPPPAVTTLHNVLPQDTEALSLQNHERIRNASSSSSSKSKSPKLGPGGGSGTFPGVGNSGSVKSSKDKSNNSTNDSSNNIVNDNSNSSVSSINKSGSNTRTTSPLSPEFYTYPTINRNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVE8</accession>
    <name>A0A9P6MVE8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bud neck involved protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">BNI4</name>
        <name evidence="2" type="ORF">BGZ80_010394</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000719">
        <property type="protein sequence ID" value="KAG0014515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVE8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030036">
        <property type="term" value="P:actin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12751:SF18">
        <property type="entry name" value="PHOSPHATASE AND ACTIN REGULATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12751">
        <property type="entry name" value="PHOSPHATASE AND ACTIN REGULATOR PHACTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="347"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="388"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="433"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="657"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="236"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="298"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="315"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="440"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="458"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="498"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="530"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="547"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="662"/>
            <end position="676"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0014515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="889" mass="96626" checksum="C22EB11720E5FF24" modified="2023-09-13" version="1">MYRPEQGSSVQDTFAAFSQLMAESAISDKATPILSLLTIDTPASTSIPESTFFPPSILSFSEKSVSSEVCSPDVLWSKPSPSPSSSMTVSTAVEQSPFLISQPIMSMSVIPAAAMGIKSTSPCISLGAGNSATSTSASLHPLVGRDYMGKVTEESSRPLSSMEYAEYQVSIIIPRISTDQQSIHPLEFDPNRDVKTFQDHGHSFKESAPASTPSGQPVIRKKTSFAERIRNAFTGRRNSSKSVEMQEDTVSFPSSGEGDKAKAHLSVNQELHRGSVSSNSSVDDTALGHSGLRRDSKQTATPLTSPDASPLASPSIKSTPALTAGQSNSESPLICSALALDAETATGGDSSELLSKSQTAVLPTKQTGIQPTPTRTIKKRLSFGSISSFFGSRSPEERRANQQRSSSLPHIESPLAIVGRQIAGFQRRHSFNDLDDSSAKTKSQPTHQLVSPSLVKDSTSTPVSTSTPAAALPPTPAKKLSLNSVFNKKLKEKKNAPKPTPPTPNSTPPAPTKPLKSALVHRPPASSPVKVHHVRRRSASTRSQGSSHRRQVQMQHRQGHHHPQRQSQNSHGPNDPLARLAEANQALALLGMGSSDHDFSTSQTQEAPAGGLYREDLHSSSQLPIDSVDVTPSVPRVPSAPLNPLAALSRSSSCCSLSSSSEDMSVPQSASSVSDDGISCYSTSLYSQSRDQIASNDEDSVAFHPILPTSAARISVARIAVEAQVKLLADIQMEDESSSSMASSPRIAGYDHQQSNYQHLKQQQQQQQLMVLDHEPFEDEYYAEDHNEQEQSLFVDADSQQSYHYQPYYYEDSYLYPPRPRRQLQFSNAEPIIHPTWTSEQYDRTSDMNITACRLTPAIAQKIKLELNQFKSQEMEVHEDSRMYTHFFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVL6</accession>
    <name>A0A9P6MVL6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_010485</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0145 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000734">
        <property type="protein sequence ID" value="KAG0014358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVL6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.70">
        <property type="entry name" value="Hypothetical protein apc22750. Chain B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035439">
        <property type="entry name" value="UPF0145_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002765">
        <property type="entry name" value="UPF0145_YbjQ-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34068:SF2">
        <property type="entry name" value="UPF0145 PROTEIN SCO3412"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34068">
        <property type="entry name" value="UPF0145 PROTEIN YBJQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01906">
        <property type="entry name" value="YbjQ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117782">
        <property type="entry name" value="YbjQ-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0014358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="96" mass="10257" checksum="231BC3B39D838CBB" modified="2023-09-13" version="1">MSRAVDRRFTTTAYAIPGFVLAQNHGLVRGLTVRTPNVGKAVFGAFASLGGGESSTYIEMAEKARETAFARLLEHAAAVGGNGKKKEIKLFTIPLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MW37</accession>
    <name>A0A9P6MW37_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Cation-transporting atpase 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BGZ80_009563</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000585">
        <property type="protein sequence ID" value="KAG0015887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MW37"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015662">
        <property type="term" value="F:P-type ion transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07543">
        <property type="entry name" value="P-type_ATPase_cation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000071">
        <property type="entry name" value="Cation-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057255">
        <property type="entry name" value="2TM_P5A-ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006544">
        <property type="entry name" value="P-type_TPase_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047820">
        <property type="entry name" value="P5A-type_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01657">
        <property type="entry name" value="P-ATPase-V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45630">
        <property type="entry name" value="CATION-TRANSPORTING ATPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45630:SF7">
        <property type="entry name" value="ENDOPLASMIC RETICULUM TRANSMEMBRANE HELIX TRANSLOCASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23143">
        <property type="entry name" value="2TM_P5A-ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01229">
        <property type="entry name" value="COF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="39"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="68"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="205"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="227"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="405"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1014"/>
            <end position="1032"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1053"/>
            <end position="1075"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1095"/>
            <end position="1119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1131"/>
            <end position="1151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1171"/>
            <end position="1193"/>
        </location>
    </feature>
    <feature type="domain" description="P5A-ATPase transmembrane helical hairpin" evidence="14">
        <location>
            <begin position="35"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="13">
        <location>
            <begin position="262"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF23143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0015887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="17">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1204" mass="134802" checksum="20151231A9A9F053" modified="2023-09-13" version="1">MAAVTDNACARQLAPASIVQTKLVKTSSLHSRLSRVQHAYVWPFIFLYPAWFYVYLFQYDEWIKSEEITFVTLGSLLTINALMFLTCQWSVSIKASLTCRKESDPAKASIIRIIPDKHRGLGALCDLHHENNSIFFFFQKKKYVFDADKKLFVKIKYPSDMGMTMGEFQKSRGLNEEQTKASTDTYGMNRFDIPQPAFMELFKEHAVAPFFIFQIFCVALWCLDEYWYYSIFTLVMLVIFESTVVWQRLRTIGEFQAMSIKPFSVNVRRNGTWTNIMSDELLPGDLVSIVRTKEDSGVPCDMVIVDGSCIVNEAMLSGESTPLLKEGIMLREADDVLELNGADKLNVLYGGTKVLQVTPPTTSLKAPDGGCLCYVVRTGFGTAQGKLVRTMVYSTERVTANNLEALLFILFLLIFAIVAAYYVWVVGSESGRKRGKLLLDCILIITSVVPPELPMELSLAVNTSLIALAKHHIFCVEPFRIPFAGKVDVCCFDKTGTLTGEDLVVEGVCGINENEPEKLIMPDQAPASSRHVLATAHALVQLEEGLVGDPMERVTLEALKWKVGRNDNVFPENPYNKSEHMLIRRRFQFSSALKRMSTVSTLSSPEFRTTKLFVAVKGAPETLKNMFTKLPKYYEDTYKQFTRRGSRVLALGYKYLPDGLNADQINALNRDNVESQLIFAGFLVFHCPLKEDSAQALKMLNESSHRCVMITGDNPMTACHVARQVDIVNRDVLIMDVREEGSGPEDLVWKSIDESKIISLDPSKPLDPTILRDYDICLTGPAMAQFENRPSFEELIRHTWVYARVSPGQKETILTTLKGCGYTTLMCGDGTNDVGALKQAHIGVALLDGKPEDLIRIAEYNQMQRLKNVYENQIKFTARFNMQPPPPHAKIAHLYPPEVVAAKQEAAREAAGIGAVDANGRPVPPARPRLDMEGISNLMEDLDEEAPPTIKLGDASAAAPFTSKLSTPMSIVNIIRQGRCTLVATMQMYKILALNCLITAYSLSVLYLDGIKFGDFQVTITGMLMAVCFMCISKATPLETLSKERPQPNIFNFYIILSVLGQFAIHIVSLIYITSEAKLIETDRTIDLERTFEPGLLNSAIYLISLSMQVSTFAINYKGHPFRESLKENTYLYRGLLAVGGVAVAGATEFIPEFNEWLQLVPFPEDFKTKLMGIMAFDYFGAWAIEIVCNKLFGNFAAKDIVRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MW38</accession>
    <name>A0A9P6MW38_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">F-box domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_010125</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000672">
        <property type="protein sequence ID" value="KAG0014977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MW38"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046956">
        <property type="entry name" value="RLP23-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48063">
        <property type="entry name" value="LRR RECEPTOR-LIKE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0014977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="415" mass="47449" checksum="43E3A754A5D53B81" modified="2023-09-13" version="1">MINTLTISTLPEAFNIQYPNLRTLSLGYEWSCYDLLSQPGKDGNTDVANLILINPKISSLKLFPRDGRINESILQSASELQDLERMTLFYARFTPGDDIDVFWRACRNLKKLRLQGTKFARDTQAPEYIREFGIRILKIEKATGMSEANQLELISRCPRLEELVWLESQPSSAGKDFVQRIAQGNPWPNLRRLTLNSCMSDDEVEKILSELKELTHLELQQASFGPHASTALLEHHLETLVELNLRSCYRATSSTFRDVLCSCPQLEVLTGPKILANDIAESEPWACLSLKVFQINVEFKESEHGDKDLQSSVFKQLSRLPKLTELYVGKEAINGTTRYPGLDFRLEYGMGQLENLKDLRYFSFRNTMQVLGEEDIEWMTAHWTKLELVSGLLHTNTEKTIELRNLLRKKDIGGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWA8</accession>
    <name>A0A9P6MWA8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_009818</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000621">
        <property type="protein sequence ID" value="KAG0015514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWA8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="253"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="149"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="253"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0015514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="276" mass="30234" checksum="24B3C4CD3F83B726" modified="2023-09-13" version="1">MATLISQTPIALGNPFSPLEFEAHHPMNIVESTSVQRMASRNDHQDDDLDLSTWCVVNSSYDDEDSDEEPGEVDQDGDEEIYLWQAPSTAYDSELPPLSDGFTNISKAAITHSTNSASATAPEHRGTWVVKVNKKRNKLQDLGNDLKQTSTSSSNISTSAPSNSTTLMPPEAMNPSEKRKETPTSVADGNSDVSEDAGPSDLYMYMTERELSKSSKAAKIKNSRVATQHGRDLAKALGCLSEETDKIDKKAIRSRSNCKSKTKSRTNKSKDLPTEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWM1</accession>
    <name>A0A9P6MWM1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Lytic polysaccharide monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_009615</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000591">
        <property type="protein sequence ID" value="KAG0015823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWM1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36182">
        <property type="entry name" value="PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G10930)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36182:SF1">
        <property type="entry name" value="PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G10930)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0015823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="230" mass="25268" checksum="3B6C1C3BE5D0DFFB" modified="2023-09-13" version="1">MAAALFYVLSTTSAHMAISNPPAQAGPWSQNPSSDVHAWIGYHGKKFPCGGYPRGPVTTYSAGDVIPVRFWNFQVTDYQTFPPPANIPQARHGGGACEFSLSFDGGKSWSVIGQYTKTCPDLYYEWPVQIPTNVPSCTDPDLCLFAWSWTAYATNQFYHHCANIIINSNSQMGRLPLLNMTVVDVTQLKQEMNTHADGDKKSTESTGPNKTQIQLNTNGFFAYGGGVKQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWP6</accession>
    <name>A0A9P6MWP6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Copine-8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">CPNE8_2</name>
        <name evidence="5" type="ORF">BGZ80_009186</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the copine family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000529">
        <property type="protein sequence ID" value="KAG0016491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWP6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005544">
        <property type="term" value="F:calcium-dependent phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071277">
        <property type="term" value="P:cellular response to calcium ion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04048">
        <property type="entry name" value="C2A_Copine"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04047">
        <property type="entry name" value="C2B_Copine"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037768">
        <property type="entry name" value="C2B_Copine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045052">
        <property type="entry name" value="Copine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010734">
        <property type="entry name" value="Copine_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10857:SF106">
        <property type="entry name" value="C2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10857">
        <property type="entry name" value="COPINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07002">
        <property type="entry name" value="Copine"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="C2" evidence="4">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="496"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="499"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="572"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="591"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="627"/>
            <end position="637"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0016491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="637" mass="69430" checksum="8DD7DF5FB3E97F85" modified="2023-09-13" version="1">MTERIKDNLNPVFVNGLQIDYQFETIQKLRFVVCDIDDKDSKNLADQDFLGEAFTDLGSIIGAVGNQVALPLTCPKHKQNRGHILIRGEELSSSKRVVNFAMRGIDLTKRGLFKSRPSAFIVIQRANENGTFSPVYKSDYVESEDDPIWKPFTVKESVLCNGDPSRPLKVEVMSYKDSGAHTVIGTTPTFSIAGLSHLQIPHSMPIPPMPGPSSLVIQSFSITEAPSFLDFIAGGGTLGLSIAIDFTQSNGDPRNPQSLHYKSPTGENEYTRAIRSVGNILQCYDTNKRFPVFGFGGRINGQVSHAFALNGNPSNTDLFIDCMIGQPEVEGVEGVLSAYWNAHSFVELYGPTNFAPVISEATNRAKSCEPYEYTTLLILTDGAITDMDATVKALKIAGEHALSIIIVGVGNANFTNMNELDGDGGTRNRGRDIVQFVAARKFPPHKEYGLAEALLAELPGQFMDYMTRHQIRPRPPIRNDTEAAMAALYHTVPAATPQYAPPVGPPPAAHHPQPQSYGAQPPSSGMHPGSVPNPGYPYNSSGNPYGAPPLVPGQQSYYPSQYGALPSQASQYPPPQGVSPMYPPQRPPFEPQHEYPAHKESPIYPFPQPDRSVSPVHPPPQQPRGLDTQNAEAVSKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWU5</accession>
    <name>A0A9P6MWU5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_009455</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000569">
        <property type="protein sequence ID" value="KAG0016061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWU5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055496">
        <property type="entry name" value="DUF7068"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46312">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46312:SF2">
        <property type="entry name" value="NUCLEOTIDE-BINDING OLIGOMERIZATION DOMAIN-CONTAINING PROTEIN 2-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23238">
        <property type="entry name" value="DUF7068"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13646">
        <property type="entry name" value="HEAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05729">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50837">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NACHT" evidence="2">
        <location>
            <begin position="169"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0016061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="685" mass="77918" checksum="90F64815F35AF244" modified="2023-09-13" version="1">MDNITPRKHEQIIGDHPINAQEPPRSEHSLKRKASHNFPTGRETPTKSAKHISNPIPDNQATSTSGSLPILLSFSHVQVALQTYYEPYLYIRRVSGDTLNLESCYINLAIVEAPDQRRKDKEGLKAQAAAFQHLPSYEEIYKTNMDAPIPLEKLFDKRKLRDGREDVPKTILVQGRAGIGKTTLCKKLVHLYQSGLWRDRFDAALWLPLRQLKTFKARGLKELLCEKYFQHSKLYSKRLANVLADHKSKILFILDGLDEILTDSQTSDGIALEAFLRHLLQQEYIIVTSRPSGVDISILPKLDLELETVGFSTQNVNDYISNVLALEDAKAVQDFIRRTPSIQNLVNIPVQLDVICHSWDSLLSNEQSITMTGLYQTMVRKLWCKDAERLQKELGISLAPQQIQRLSPYQIDKLMATVSEYLSFLAFKGICDHQIEFDESTLQKTTEELDELREMVNQGHLPYQLLDSLKQTSFLHTADAELDTGKDDSQRAWYFLHLTFQEYFAATWIARHLQIKQKSPKTRSAPMMTMEETKAYIRKHKYTPRYQIVWWMVAGLLQGETLVSFFELLQGAPVDLIGGYHHHLLAACLDEGRSQLDDKSVENVEIQLEQWLRFEAAVNDNSDGMKSTLPESTLQALIGALQDESEYVRNSAASALGMQSTLPDSTLQALIGALQDENEYVRSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWZ8</accession>
    <name>A0A9P6MWZ8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008977</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000507">
        <property type="protein sequence ID" value="KAG0016730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="17798at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1422"/>
            <end position="1441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1447"/>
            <end position="1468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2049"/>
            <end position="2083"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2133"/>
            <end position="2183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1426"/>
            <end position="1439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="2049"/>
            <end position="2063"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="2073"/>
            <end position="2083"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="2133"/>
            <end position="2150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="2157"/>
            <end position="2176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0016730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="2336" mass="262064" checksum="3D7E6954C1F54AD2" modified="2023-09-13" version="1">MSSFSQFQEDYALNPELRPELVKGTTPGTEDHFLYRLKYLSQRLQTAEVPVTSQVIEEAIALLKSAENSNVVTDREQLEQLKAQIALLAFPVKPDILLKQLNFDPGMNYVSQTGTLDHAQEQVEEGDGSLSGSTNGVESLPTNLDQSIIKTETLTEKLLDQIRDDFYGAQIPSDAWPHLIAQPRMEGILDQLDPDQLNYLFSNMDIMYSSKSLEIIGKADTSRFDLIMVKIILRLYREKKIDFSDASSSKQFRSLTQVQLEAIKKEEFNQVMNNEGFVSLLERKIVPEPFPENEEDAVKEWLDRMVKFVDQLPPKFNFHKLSVYLQSLELDMAHGVMDKEKFIRYIAIPRNQAQYNQKALTHYDSNQLVDLTRYYSLQNWSGRVDPATSSRDDEVVREYLDHFMKEAKSSAEFEEFFEVKSFLNPLLAQVMLASGDKDVAKWSGLLPANENLTKLTEKTILKFVPNNPTKFLPSDPVVFKLRAKNAKRILVRVFEIKTFECLQHHSGGVLGQNLNLDGLTPNWEHNLTQDHPPLEVHEVSIELPELSNRRGAFVMDVISNGENSSAYFTKGCLDFIERQSVAGHVLTIIDENQEKLSEKCTVWLNGYYYKPNGDGDIIVPYRKPSSSSSSYIYIIHDGFTTRRPFNHRVEGYTLKLAGHIDHESFVAGSTAKIILKLTLQIQENIVICPISLLERVQLTIESFDTNNISATTTVPDFKVHDVDWSEYNFQMPENVSSLQVTLTGRIKVISTGEHQTLKASRRFTFANPNSDQNVSFENNGIWQTTLVPGEIVTLLQKCSDGYKILALGRNGEKRPGIPLEFEVTHPIWIKRLNFYLRTDDNGQAHLGPLRDIDVLACTTSCMRWQISGREQHAHQEIIHGVEDEHISLPFERHDIGIIRKIALFSITGQSESINSDSVLSDYTDNIRLADGLLTIKGLKAGYYHLKVGEKVSSRLVIAQAGATKSKIQGLEDFVIRSNPMMETTESTKHPLYIAEPVSNAGNVDIQLYNWSPETRVCVVATKFIPFDDSLFDHLKVLENEVPWTMKKAELTPVSFKTGRVLGEEYQYILNRKSYTSRWAGNLLTKPSALLSPWSVAETTMSKQDMRAENLENAQIKAKNFAFAAGQARPCASNYFANSMGSMPSRAPPLLNFLVHPSVMLVNLIPDSSTGLISIPYSTFREGTFLQIFALDGFQAVQQSFVVPRPSSDPLGFQKRDLRFKSQLIHTKHYIGERAGVELDPKLHATASSSGVSTASVTLASNGSSSAVRVINSISQVYDLMLTLLPTEEAKQTLREFGVVVDWHNLPSPSKRERLSKLASHELHLFLYKKDRPFFDAVVAPFLKNKLVKSFMDDYLIGASLEKYVALDEFKRLTCMEKCLLAQRIPSLKPAVARWIKDRINITRQASNVKLFLTVMNSGSLKESAPGGVGGDDGGAGVGGSANRPMYAPASAAYSPTSPKEESDGDDDMGFEMFDSVSRAYAAPPVPSIQPLAAPIAPAAPQRRMMFRKVNTSHDRERDRERSERIVQMQFKPVDLTKEMAETYYYGRQDFKADDEGEANPFWLDLVQWDDSKGGYFLSQNFIANAGSFTDAMATIALVDVTFQPKDASLARTANNNLAISSQSPAIIFHSSTKELAEVPVTGSVLVTQQYFEQTEKTRYDEAMRSQVRHYIQPGTELRPLESYGAHVVLMNATPNPMMVHLEVQIPQGAISIYGSLESGQDIQLTPHGTFQYEYGFYFPEEGEFTHYPAHVSNYEDIIAFAAPALLKVRAPAPDRRETDTGTWNHILKRGTKDDILAKLQSSPLSSVPVDQLLPRLYRDKRLLQLVTSELRSRQEYSEAIWSVGLAVHDQGLVKEYLMNQPPSIINAGDWFTSSVYVCKPRSRLEGSWDNSLRYLEYFPLVNARAHKATRNATILNNKFKDQYNHFLKYLSQKARHDADDLLMLIVYLLAQDRISEAKKTFRQLGTMMSSNTNVSREFFQQIQYDYLWAYLSLCIEIQAEPSTKNPTLDLTEVQSILNKYRDYPVERWRKMFNDMQSYADEIVQSYSETEYSASAPEPQSSSGAEEAANANTTDDEDEEDDNAPEVPVMVDFKIGNGNIMEVRYRGVRQVSVEYYSIDAETMFSASPLTLCEQSENESSSTESFSSSAGEATPFGFSSSGQSSSNTNNSSGDSSNSYRLVKPNGVDSHSVKRAVANDGILMIPILSQFQNTNVIISVSTSPPAATRTWKAYYSQTILVQCMERTGILKVISKTDGRPIRGGYVKVFAEMKHDSTAVFWKDGYTDLVGRFAFAQVSTGVASGSGTGGGGLGDVKRFAVFVDGGREGCVVKTLPVPPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MX03</accession>
    <name>A0A9P6MX03_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 10">Fructose-bisphosphate aldolase</fullName>
            <shortName evidence="10">FBP aldolase</shortName>
            <ecNumber evidence="5 10">4.1.2.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">FBA1_2</name>
        <name evidence="11" type="ORF">BGZ80_009355</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 10">Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:14729"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.1.2.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="10">Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the class II fructose-bisphosphate aldolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.13" evidence="5 10"/>
    <dbReference type="EMBL" id="JAAAID010000551">
        <property type="protein sequence ID" value="KAG0016232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MX03"/>
    <dbReference type="OrthoDB" id="35652at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004332">
        <property type="term" value="F:fructose-bisphosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00946">
        <property type="entry name" value="FBP_aldolase_IIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000013">
        <property type="entry name" value="Class II fructose-bisphosphate aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000771">
        <property type="entry name" value="FBA_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006411">
        <property type="entry name" value="Fruct_bisP_bact"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00167">
        <property type="entry name" value="cbbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01520">
        <property type="entry name" value="FruBisAldo_II_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006628">
        <property type="entry name" value="PRK09197.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30559:SF0">
        <property type="entry name" value="FRUCTOSE-BISPHOSPHATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30559">
        <property type="entry name" value="FRUCTOSE-BISPHOSPHATE ALDOLASE CLASS 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01116">
        <property type="entry name" value="F_bP_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001359">
        <property type="entry name" value="F_bP_aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00602">
        <property type="entry name" value="ALDOLASE_CLASS_II_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00806">
        <property type="entry name" value="ALDOLASE_CLASS_II_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="9 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU366023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0016232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="358" mass="39052" checksum="183DF4A6B7B8106D" modified="2023-09-13" version="1">MGLLDIVPAGVITGDNVRKVFAYASKEGFAIPAINCTSSSTVNAALEAARDAKSPIIIQFSNGGAAYFAGKGISNKNEQASILGAIAGAHHVRTVAKAYGIPVILHSDHCAKKLLPWFDGMLAADEEYFAKHGEPLFSSHMLDLSEESKEENIEICVKYLERMAKINCHLEMEIGITGGEEDGVDNSEVDNAALYTQPQDILDIYNAFTKITDLFSIAAGFGNVHGVYAPGNVKLHPELLGKHQAYVKEQLKLETDKPVWFVFHGGSGSTEKDISTAVGNGVVKMNVDTDTQWAYWAGIKDFYESKKAYLQAQVGNPDGPNKPNKKVYDPRVWVREGEKTMVERVKVACKDLGNVDRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MX55</accession>
    <name>A0A9P6MX55_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Eukaryotic translation initiation factor 2-alpha kinase 1</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">Hemin-sensitive initiation factor 2-alpha kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="primary">EIF2AK1</name>
        <name evidence="22" type="ORF">BGZ80_008694</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="18">
            <dbReference type="Rhea" id="RHEA:17990"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="17">
            <dbReference type="Rhea" id="RHEA:46609"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="16">Synthesized in an inactive form that binds to the N-terminal domain of CDC37. Has to be associated with a multiprotein complex containing Hsp90, CDC37 and PPP5C for maturation and activation by autophosphorylation. The phosphatase PPP5C modulates this activation. Homodimer; homodimerizes in presence of heme, forming a disulfide-linked inactive homodimer. Interacts with DELE1; binds both to full-length DELE1 and processed form of DELE1 (S-DELE1) in response to stress, leading to activate its protein kinase activity and trigger the integrated stress response (ISR).</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. GCN2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JAAAID010000480">
        <property type="protein sequence ID" value="KAG0017011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
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    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0832">Ubl conjugation</keyword>
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    <sequence length="1372" mass="152639" checksum="CD32A8C6CAB58E1D" modified="2023-09-13" version="1">MADKDSDEPSDDRPTSVNISSWSRRSRATENSRIRIGIDSRGTDISPDRFGRCQETQLDHGPQSTLSFRPGRRDRGLMRNTTVMTFHSDSEQEHEGPPFSSLLGRRGERLMRTTTVMTLQSGSDNYDEESNSDSNFDNSQSSFSSDRQGHSRVDIGLARAFRDVNSRDPTNSRSHRFVWPGPGTSDDDQTTSDDDENTDSAAQGSHIDIMIQSDCGDDEGQIDEDEDEEESRRPDMSNVLGSYLLAPMGFDDDEGAASSHGIEGYSEAAERFQIFAGVNEFDESDQIGFDDNTYQVIPKSKRRNQERILENKRRQGRLLLVSLLDNFCLLYEQSPERNRKLFYVICKTLSNMGIIDEEYLEEMSAVRSSYQRAFRSLVLSALTSIKQEQMILESRRIMAPPSTPTGNTDRRRGGHRHDMGSGYSSQSISESFSSKGLVPSVYLHSLPVSDSSFTPPTSMMRTTSFGDMFDNDPTRYKHDFVEICKLGKGGFASVFKARNKLDGIEYAIKKIRLRGSSKVRYEKIFREIKFLARLDHKNVIRYYSSWLEHADYPVSRREMYYSGGDFDSIGEPDDDFDDEYGDEDEFTNTASMREDPTMPQRTRRRRSVDYFGPHAEQHPSELEDLSMGIVFGEDGEDEEDDGITFEETQGMSDLDEDDASRRGSVQKSYSLMRGEDMSRNYSVSSTLASRNIPGALKRNPQRQKHKSPTVSQELDGVTQTWEETEASPSKARSNMANSFSTLSSSIEEIQRSLPSSYSGLGSRSQPRNHTLAALGGENELQPFTFPNLRESDRSKFAGGDIGGVNTQGRGDRGNPRTHRNSHGQLVSRDLTLFIQMQLCQTTLQDYLVYRNERPVLISRSNSIESNKKLAKASFLGIPSSSVLNDQKTQSAPGSPLQQTCHRDLVDPAVNQHIFRAIVEGVAYIHAQDMIHRDLKPGNIFLGMPAGVEHLRGHHSRLDNCNPDSLTSTSISSSQAGTLTTPSISSESPPNYTSTNPVQPPLTKEQIQEELFLNIESMVPKIGDFGLVTDMEGGATLDDDNSSQNTIPVTTPTENPSSAPLMRRHSSTVTTGSRSSRTRTTAVGTVTYASPEQLARPNLGYDQKADIYSLGIIFFELYHPFSTLMERHAVLRTLRNGELPPDFVSRWPKEAAFVLWLMAEDPRLRPTASEILEFDLIRKQKEEPIILSAATNPGPTSVAVSTETESPGIKKTSEAFCGLGLDSPVPVNPNIVSSTGMTIEPCVAREICEACQSRCQCSEPAVATAVATAAAVNAAAAGVIDNPIDSSAVTNSGQGKTRHQKGHRSSKSVSGKISRADLEQRLKEESEKVQRLEMSMAAMRAENKALLDRIQALEYEKEMSWASGRRSVDRDCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MX65</accession>
    <name>A0A9P6MX65_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_008654</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000477">
        <property type="protein sequence ID" value="KAG0017049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="term" value="C:actin filament"/>
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        <property type="project" value="TreeGrafter"/>
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    <dbReference type="GO" id="GO:0030041">
        <property type="term" value="P:actin filament polymerization"/>
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        <property type="entry name" value="Formin_Homology_Diaphanous_sf"/>
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        <property type="entry name" value="PROTEIN DIAPHANOUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45691:SF6">
        <property type="entry name" value="PROTEIN DIAPHANOUS"/>
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    </dbReference>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1182"/>
            <end position="1192"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0017049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1412" mass="158014" checksum="3D0A5971FA2BB2B1" modified="2023-09-13" version="1" fragment="single">SRGSFSRSRSNSLQSRSRSHSRSRADRHSRYSSLSRSRSRSISRSRSRSPHSRASIESENVTKDADFSIKGNNTSRFSWQSTGGAPSHRRSWESTVSGTAPKSRDTIDSFNGPDATPQHPLGEAELSDYEPEHGTKKDGGVDAKAHISEAEVRKPLTQQGNSKVLDDSDTDSMDSPPLKVQYGRRNDDGDDETFSSKHPVSIISTFNLPPATSPTSPPRPPPLPSLYPSAVANGSGPSPPPVPQSPPLEEAQNQSLMTAITTVSIEAATSTMLSSRVSVESFRNVPGNTGTPAHRDGKADTDIESDMETYAESDAIKHDRSPIQPSYVSMTSTSGNEQMSSSSTPMTPLSNPLSITTSQLRRNESSTSSISVVSARSARSFVSTSSSHSISSLLSGSPPPQRAPPPIPGADSAAGGATIGSGLFGGKRTGSGGSARGVRSGLSKQIMPPVIPPPPGPPPEVSGSKPSYGIIPPPIPSSLNGPLESTSDTTKNTERNASASVSVSASASASASSAIQIQMLADEDQSKSQFGAITLENDERLMTRLNNRVAQLEKELEFAQQDLDASQDDVLDLQSKVRELENELDEVSKKPGTEESERQAAVSEEFKSAKESWEQERAQLLQGLENLRKDHQVELESSLEREGLKLAEELERLASEHATAMEGKAAEAAQERDILHDEHRRALEDQKQHLESEHKQSTDGLLSQLESLTVLHAEKLEEQRLEHENRALENQRGFDAQLLSTQEDAAKNLESVNVIHQQQIGDLEQRLEGMEKSLTEISSQRDQAINDLSYHRKETERALDRLEVVLAEDKKTHALLIQSLEQKSKKLKERIAELESEKGELMQDNVQIVEEMQKREELWAQERAQLRSGNADENEAMIRLQEAHDHLAALTESKRQADSQFQGIVKGLLREASANKKEIEEHRNMLEQERNAKEEAMQQLELIQQERHSLQQEKHNLEQEKQDLQQEKQNLQQEKQDLQQEKQNIQQEMQIIQQEVQGFERMMQGLQQEKEDLQHEAQSLLREKELANEKWASVESNRGDMEAQLEALKKSGDEALLNIQNELQDRVRQLQQDLESERGKSLSLESALEQGLSKAKGELQQEQFTWKTRLDQVEAALKTKEGQVRRLEQEANATVKIQSDLVQSMERDAANSVKKLEAKMKEMELSFAKEKERLQQQMQQDFAKRHEQDSAQKEASLQQQLESIHKQELEMAKQDMASKHDQQLRSLRQQHEAALAQSNLSLKQQSAAIDEQLEKLRQQIEQERSEKEVAVKDRTFLERKMAGHDRRQKELEESLAALQQQLDQSRSKFGKDLQEVERTKLSLERKLSMAKEDVKELNKIRDELENDRDGLRQEVQRLKKASLGKDPSAGANTGAWEAEKHRLQEQVRKLEDEVQIMLEKNMNLTIELSMRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXT4</accession>
    <name>A0A9P6MXT4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_007832</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000409">
        <property type="protein sequence ID" value="KAG0017860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXT4"/>
    <dbReference type="OrthoDB" id="288590at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050231">
        <property type="entry name" value="Iron_ascorbate_oxido_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47990">
        <property type="entry name" value="2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00682">
        <property type="entry name" value="IPNSYNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="3">
        <location>
            <begin position="210"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="133"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0017860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="391" mass="44480" checksum="D32E41A20B416B42" modified="2023-09-13" version="1">MSVHSPRNTVSSVLPKMLCLSAKDNSRVNDAARVPMIRTLSLKDYLCPEARPHFLREMRESLVEIGTFYIKDHGVPTQVTEGVMRTMRDYFALPLAEKKKMLIGNSRHFRGYKLMGEERTNNQVDHREQLQFGPEQSSNEDFMPSASPEYQGLKGPNQWPSTTLALMPEFKTCILEYMRQLETLSQHLMEALALSLNLEATYFRDLFGETPYYRLKCAKYPSVQNAATVGCGAHKDTGFLTVLFQDMVSGLQGEDPVTGRWMDTRPVPETFIVTMGESIEKLTGGLYHATVHRVLNNTSGQDRYSIPFFFDPTLEAEIPYCIPLVSHRGFGPSLSAMPVSDSSVDEDLESLVDRFDINDNGVHNKNWSNGKHIFETVQRCHPEVYSRWYNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MY36</accession>
    <name>A0A9P6MY36_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">60S ribosomal protein L27</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_008844</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000494">
        <property type="protein sequence ID" value="KAG0016870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MY36"/>
    <dbReference type="OrthoDB" id="2365484at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06090">
        <property type="entry name" value="KOW_RPL27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.770:FF:000001">
        <property type="entry name" value="60S ribosomal protein L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001141">
        <property type="entry name" value="Ribosomal_eL27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018262">
        <property type="entry name" value="Ribosomal_eL27_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041991">
        <property type="entry name" value="Ribosomal_eL27_KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038655">
        <property type="entry name" value="Ribosomal_eL27_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10497">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01777">
        <property type="entry name" value="Ribosomal_L27e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01107">
        <property type="entry name" value="RIBOSOMAL_L27E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0016870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="130" mass="14996" checksum="05404A690C62B556" modified="2023-09-13" version="1">MVKFLKSGKVAVILNGRYAGKKAVIGTKERGYGHAIVAGVERYPLKITKNMGKKRVAKRSKVKPFIKVVNYNHLMPTRYGLELETLKSVLTVDSFKEPTQREEAKKAIKKLFEERYNSGKNKWFFTKLRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-10-08" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MY51</accession>
    <name>A0A9P6MY51_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="23">P/Homo B domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">BGZ80_007406</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase S8 family. Furin subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000379">
        <property type="protein sequence ID" value="KAG0018231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007323">
        <property type="term" value="P:peptide pheromone maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04059">
        <property type="entry name" value="Peptidases_S8_Protein_convertases_Kexins_Furin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.260:FF:000026">
        <property type="entry name" value="proprotein convertase subtilisin/kexin type 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.200:FF:000005">
        <property type="entry name" value="Proprotein convertase subtilisin/kexin type 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050352">
        <property type="entry name" value="ABCG_transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034182">
        <property type="entry name" value="Kexin/furin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002884">
        <property type="entry name" value="P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041:SF119">
        <property type="entry name" value="ROA1P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01483">
        <property type="entry name" value="P_proprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51829">
        <property type="entry name" value="P_HOMO_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 16" id="KW-0645">Protease</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 16" id="KW-0720">Serine protease</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="5 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 18" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="13" id="KW-0865">Zymogen</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="442"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="477"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="519"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="557"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="593"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="682"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="1129"/>
            <end position="1147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="1199"/>
            <end position="1225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="1232"/>
            <end position="1248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="1254"/>
            <end position="1279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="1349"/>
            <end position="1378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="2071"/>
            <end position="2090"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="19">
        <location>
            <begin position="69"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="19">
        <location>
            <begin position="774"/>
            <end position="1037"/>
        </location>
    </feature>
    <feature type="domain" description="P/Homo B" evidence="20">
        <location>
            <begin position="1871"/>
            <end position="2015"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="37"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="2014"/>
            <end position="2062"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="2099"/>
            <end position="2118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="2126"/>
            <end position="2253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="44"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="17">
        <location>
            <begin position="2023"/>
            <end position="2035"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="2053"/>
            <end position="2062"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="2135"/>
            <end position="2145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="2148"/>
            <end position="2175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="2198"/>
            <end position="2220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="2244"/>
            <end position="2253"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="15 16">
        <location>
            <position position="1585"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="15 16">
        <location>
            <position position="1623"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="15 16">
        <location>
            <position position="1795"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
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            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR615500-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAG0018231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="23">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="2253" mass="247515" checksum="61A900896D3B4EDE" modified="2023-09-13" version="1">MKNTPHDSATSSTGIELTVRNLSLSVVPPPSIFTRLARKLRSDPNPNKSSKSDTSITTNLDDDDDVAVVNGSSVIEPTVDEKGDRDLRNVGTNIFRNVDLSVKPGQVCIILGGSGSGKTTLLNTIAGRMRGTEICTSGSITCNGAKAKKYWNDGSVGYLQQNDFLMPFLTVRETLTYAAHLRLPRTMSSQKKRELVELVLLELGLKECADTRVGDAGGGESGSGGIRGISGGERRRVSAGVQLLTNPKMLLCDEVTSGLDAFSSYEVMKSLTKLAKSSQKTIIISIHQPRSEIFSLLSESDGQMILLSRGDVVYSGPVRSVLPWIESTGVGACPKGVNPFDYLLDLSMIDFASESIEKSTAIRREMLIQAWAQRKSSVLDNFVRDPSMLTSSGGESSSQPVVASTFASLAVDIIPKGAGPSLWNQARILTVRGWNNQVRDSLVFWGCVAECIIIGLAVGAAFYDMDDTLSGIRSRSSLTYSVGAIQSYLMLMVFIYRLSQDIVIYDRERIDRWYGPLPHIISTFLYSAPSNIVYPTVFSPIVYYLTGLRTDSGIHFLWWLIVNILMQFSTFSFAVLCSSVVRGFSTASLLGNAIFAFFGLTTGYFIVTSSIPVWLRWIKYIAYPNVGYAILASNEYTDQRFGCPYAMNGTWDPVACAPYDGNSILAQLDLKPNHYPAPIAELLCYVFGFLFVAWFALTVNVVNPTSMGAGPTLADIFISYFKDIFMGKKPVAATGPKFTSSDSGASTDDEKTTLEETRLDVFSKGLQQKEPVTIRVEGLSLSVFLSKFEWSFTGILSWLRREKTEKRLLKDVDVVFPAGELTAILGGSGAGKTSLLNLLLHRSPDNLKKSGSIYFNDTKDPSLRMINGVSSYVRQDDSFLLSHLTVRETLQYAAELKMDDSISKADKYAKVEDIIELLGLRECADVIVGNNVVKGCSGGQRRRVSIGIQLVTEPTCLFLDEPTSGLDALTAKSVVLTLKQIANSGRTVVCTIHQPRADIWHVFDNVVLLVTGGCAAYSGRADKVVEYFEDAGHIAPPLTNIPDFILDTASVNLRSIELEESTRKTVNALVDRFNMNKHVMLASQLTGHALGELPKVNPQYASFVKAFPILTRRSFVNTFRQKGLYFNRILQPAFVGVIMCIFFAPLGRGPNDVLSRLGLLQQTSPMVFTGMLNNVAIYPFERDIAYREMSDGGYSPTSFFVSFLVNELPLEVFGSLFVTVFMLVVTKMQTTVVTFFSFWFIMFGYINAGESIGLAFSSFASHAGFNITLMSAVISFFSFMTGFMSASIPEWLEDINYASLFKYGSTVLCRNEFEGQTFDCPAGSPGGCPFLTGESVLVQFGFQDRNWDLYMGLFAAVITTGHMKPILLLLSAVAFIAAAPSAQAAKSSLIQDAVNNHYYAVKLNDLDVAPPNEIAQLLGVQYIGQVGELSNYHLFSYPKTAFEKRSDASALSSLDGQHQDIVVKRYERLRQSKSFHQELMVRKRSFAGSEADAGSSADLHPLGPIHKQFLRKRVKRAMVIEPRDEYVKGEDQPKDDIAAHFQITDPGFGYQWHLHNTIQRGNDINVTGVWDQNITGKGAIVAIIDDGLDATSDDLKPNFYAKGSYDFNDNVDIPLPRLFDDNHGTRCAGEIASARNDLCGVGVAWDAKVAGLRILSGEITDVQEAEALNYNFQETQIYSCSWGPSDDGVAMDGPTGILLDAFINGVTKGREGKGSIFVFATGNGGRVGDNCNFDGYTNSRYTVSIGAITRYNEHPAYSEPCSAQLGVTYSSGDNTYIYTCDVGKRNCYARHSGTSAAAPIAAGIYALVLEVRPDLNWRDVQYITVHTAVPIDENDPDWTETSVGRLFNHKYGYGSLDAYAMVEHAKTWVSVGPQVTYESPIIVVNGDIPSGIDENTGQTGQIGLPSVFEVTEDALKGVKFGTLEHVTVTLNVRHEFRGEVEVELRSPDNIVSKLAEARGFDDSTEGFVNWTFMSVKHWEENPIGRWTLTVFDRRNPSKTGTFIDWKLSLHGEIEGGHDNTPIPDVPLPQPEPPKSQPTTTPAIPEETSLPTNDADKSEEGDSHVSIEISPFIYVMFAGMFGAIGVALFLMHRHRTNPRNFFGSNIDDEESGQRGGLLGRRSDYEFDELPTHDLGGSDDSDDDDNVNSDSHRVVFDRSHIIDERGEARTQEAKASQRDSSSPLSSGEEIERESSFEVAGVEEADDDDDEEDDEDDDDDDDFGDHPGGSVSKIRSGSWDEFSTLVRSKDGKSVRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MY82</accession>
    <name>A0A9P6MY82_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Serine/threonine protein kinase psk1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">PSK1</name>
        <name evidence="10" type="ORF">BGZ80_008363</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000450">
        <property type="protein sequence ID" value="KAG0017367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MY82"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000048">
        <property type="entry name" value="Protein kinase C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017892">
        <property type="entry name" value="Pkinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24351">
        <property type="entry name" value="RIBOSOMAL PROTEIN S6 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00433">
        <property type="entry name" value="Pkinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="219"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="9">
        <location>
            <begin position="480"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="160"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="201"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="570"/>
            <end position="590"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0017367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="618" mass="68055" checksum="CD6D7378F5DEE59F" modified="2023-09-13" version="1">MDMFSFDQDDHPRLRERTFSVDSVQGIGSPQDALASLHLDSHERNTTTNVTTVKNGLFGQVNVSHCPILAPRPIAPVFSVAAKTSTTATSTTLANAEGLTTIFSSSTSSQGFYQTNNNSSNKHLPTYFYQVDREQAMTPESTFLKSRAQQTNGVVPAFATTVTANPSPDPPAISSTQSSDGESENVEYEVRIDQDFDAHAPLTADSRGQSPRPGQPSTGLTSNAQSGVKYGKVYLVRHIVSNALYAMKVLKKASIIVHAKDTECTMSERKILEAIRHPFIVKLHYAFQTDHRLYLILEYASGGELFTHLATERMFSEENTAFYAAQLVLALEHLHSLGIIYRDLKPENIMLNAHGDIVLTDFGLSKVPLENSDGRTNTVCGTIEYMAPEVISERTHYDRTVDWWSLGIVIHDMLTGSPPFVANNRKKTMDAILNKKLNLPYYLSSDAKDLLTKLLKRVPTARLGYGLKGVENIKNHRFFRKINWKLLALRELEPPIVPFLSDPESVENFNSEFTELPVQESPIFTHDMTRLQGGIEGGDGSNTPVLGSGHHTPSRYMTAPSSASSGGLGVMNGQEAGGIPMAKTRSSSPDHHHFPDFSYISTSHLPSLGYLDALGDEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYL1</accession>
    <name>A0A9P6MYL1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Casein kinase substrate phosphoprotein PP28 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_006786</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000337">
        <property type="protein sequence ID" value="KAG0018749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYL1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019380">
        <property type="entry name" value="Casein_kinase_sb_PP28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039876">
        <property type="entry name" value="HAP28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22055">
        <property type="entry name" value="28 KDA HEAT- AND ACID-STABLE PHOSPHOPROTEIN PDGF-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10252">
        <property type="entry name" value="PP28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Casein kinase substrate phosphoprotein PP28" evidence="2">
        <location>
            <begin position="100"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0018749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="199" mass="21655" checksum="5C8D056E0F211B63" modified="2023-09-13" version="1">MAGGKFKKPQRGGGRKFSRRIEAVHTTTTQSNAGRGGKIETPKELALSGSESGSESDARSGSKSGSESKSESESESESGPESDSHVESALEICAQTITINPNHLQPVVNKRQKNKPLDMNTPIIEMSRKEREAAEREAAKQRYWKLHQEGKTDEAKADMARLAIIRKQREEAAAKRLAEAKAKEDAAAAKIGLTPSMRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYQ5</accession>
    <name>A0A9P6MYQ5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_008413</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000455">
        <property type="protein sequence ID" value="KAG0017308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYQ5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42861">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0017308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="232" mass="25208" checksum="A8612FB1481D5DC5" modified="2023-09-13" version="1">MAMGTKGLARRKVIVKRLAAVDFNDPIGFAIRTAAEEQLGVLKDRVYKHKAPCFRVISFLPFKSSTRMTQATVMDLQAQESFKVIKGGSPGATCVRHGSLGNCELVGMVPLVDPPHPDSAETIRHCDEMDVDVKKLLISLGMSRVIMDAGHLVDAGKSDRGVTEHCIRAGGLAQVIPEHKYRIVKLLQNRDILAGITGDDVPGLSTIVDGLMTSHANAFLCPLLNHIKRSTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZ55</accession>
    <name>A0A9P6MZ55_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Sulfhydryl oxidase</fullName>
            <ecNumber evidence="6">1.8.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_007532</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>2 R'C(R)SH + O2 = R'C(R)S-S(R)CR' + H2O2</text>
            <dbReference type="Rhea" id="RHEA:17357"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:16520"/>
            <dbReference type="ChEBI" id="CHEBI:17412"/>
            <dbReference type="EC" id="1.8.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.3.2" evidence="6"/>
    <dbReference type="EMBL" id="JAAAID010000388">
        <property type="protein sequence ID" value="KAG0018113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZ55"/>
    <dbReference type="OrthoDB" id="59470at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016971">
        <property type="term" value="F:flavin-dependent sulfhydryl oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.310">
        <property type="entry name" value="ERV/ALR sulfhydryl oxidase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039799">
        <property type="entry name" value="ALR/ERV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036774">
        <property type="entry name" value="ERV/ALR_sulphydryl_oxid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017905">
        <property type="entry name" value="ERV/ALR_sulphydryl_oxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12645">
        <property type="entry name" value="ALR/ERV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12645:SF1">
        <property type="entry name" value="FAD-LINKED SULFHYDRYL OXIDASE ERV2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04777">
        <property type="entry name" value="Evr1_Alr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69000">
        <property type="entry name" value="FAD-dependent thiol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51324">
        <property type="entry name" value="ERV_ALR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 6" id="KW-0274">FAD</keyword>
    <keyword evidence="2 6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ERV/ALR sulfhydryl oxidase" evidence="7">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU371123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0018113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="100" mass="11232" checksum="8B272CA7B3A9BD50" modified="2023-09-13" version="1">MAARYPLKPKPDERAAIKQWIFLLSRLYPCGECAEHFQQLLKEHPPQTSSRASLSNWACAAHNIVNERLGKPEFNCGTLADVYKCGCADEPKDDEDIVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZX3</accession>
    <name>A0A9P6MZX3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Chitin-binding type-4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_005134</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000255">
        <property type="protein sequence ID" value="KAG0019877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZX3"/>
    <dbReference type="OrthoDB" id="2341272at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35559">
        <property type="entry name" value="CHITIN-BINDING TYPE-4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35559:SF1">
        <property type="entry name" value="CHITIN-BINDING TYPE-4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040156768" description="Chitin-binding type-4 domain-containing protein" evidence="2">
        <location>
            <begin position="29"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0019877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="246" mass="27233" checksum="41F2328FDF4BD908" modified="2023-09-13" version="1">MLFSSISKAGLALIATSIILSFTTPVESHSYVDCVDWRFKNPKNPSWSDKNGVCHGYARRFPLKAKPFAKLDSDDPNRHYQQTHKNPDADHALPCSNGKVGEEPGADETMAHPVTAAYSGKDKRGRKTGAMTTAKVGDELCIRWPAKNHAVPSEKNNPVTIAFSKDANPTKDPSQQDFLHNIVATLNYKNCTDKGKNTDIWPCGGCFKIPKSVKPGYHVMQWRWMLNGDSGKEHYTSCADIKVLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZZ6</accession>
    <name>A0A9P6MZZ6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_004723</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000238">
        <property type="protein sequence ID" value="KAG0020133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZZ6"/>
    <dbReference type="OrthoDB" id="2143914at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019185">
        <property type="term" value="C:snRNA-activating protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001006">
        <property type="term" value="F:RNA polymerase III type 3 promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042795">
        <property type="term" value="P:snRNA transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042796">
        <property type="term" value="P:snRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051575">
        <property type="entry name" value="Myb-like_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46621">
        <property type="entry name" value="SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46621:SF1">
        <property type="entry name" value="SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13921">
        <property type="entry name" value="Myb_DNA-bind_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Myb-like" evidence="7">
        <location>
            <begin position="84"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="10">
        <location>
            <begin position="92"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="10">
        <location>
            <begin position="138"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="7">
        <location>
            <begin position="138"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="9">
        <location>
            <begin position="141"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="7">
        <location>
            <begin position="189"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="10">
        <location>
            <begin position="194"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="746"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="822"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="400"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="509"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="705"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="778"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="400"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="444"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="513"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="705"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="779"/>
            <end position="808"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0020133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="857" mass="94030" checksum="A75FDBBCEE899947" modified="2023-09-13" version="1">MAVNMSYGSPSDFEPYSHFVYQASSQLDFTFYAPPHEGGSKDDPVPAAVFNAALPEDMPSLDLTGEANIDDLLNLDEIATPRKRDRGERIVWTPEEDEFLRAAVQMYGDKTEKWAKIAACVPGRTNKNCRKRWFHSLDPKLKKGPWTEEEDHLLRTGVQMFKGQWSKIAERIPGRTDDQCAKRWREGLDPLIDRAAWTREDDIILLQRFEEFGSQWQKIALAFPGRPGLHCRNRWRKIQRGLNHMKRVGKRRSQGSATDHAAVISETRRLEALLDSSNDDPDADVHYNATEDILLMQDAYLDDDFALEHGLMIDENGLAVLTDPKGEQQDANGFEDEKPYGCAVPDCSFESSSPSLLYYHFKASHAGTAVEKPFRCTMPGCETRKRYKNINGLQYHVTHAKNSPGHSGNSGHTINTHTGDDGADFSKVARTARQTTPSGHGKLSNAPQSNASSPSSDLRILMPAVTFDPAKVALSNPPTPAELQLQLHQSKQDHPSQLAIPHIARGAFNIPHSPSSLDASAASSQASSGASSPHIHRTVFHCPELGCDQTYHQIHGLNMHMANAHGHRAMNMRSSETAYGAESMVMPQETRVDFDIDMADLTSRPPSPMETNILLLEDSILRRQLDGVELMSMDTSSTPATSQDHNKNCNNGNPTFGMLTGKEFLFNSHAAGSIQNRVHFGSHISVGSHEPILLQPAQTIPIVTSPSGSISSASSSGIASTPSTPPTTVPQKPTKGQSSRSVSKRFACSALNCQKSYATASTLNNHIRNDHPDLYVGNAVNTAGSRTSASSPKAAQRSQASSENTRSSDLPREDEDPVDWPYKCLVPGCGKGYININGLKNHLLQTHGSTPKSNPAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N015</accession>
    <name>A0A9P6N015_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_004969</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000248">
        <property type="protein sequence ID" value="KAG0019986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N015"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005960">
        <property type="term" value="C:glycine cleavage complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019464">
        <property type="term" value="P:glycine decarboxylation via glycine cleavage system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009249">
        <property type="term" value="P:protein lipoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002930">
        <property type="entry name" value="GCV_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033753">
        <property type="entry name" value="GCV_H/Fam206"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11715">
        <property type="entry name" value="GLYCINE CLEAVAGE SYSTEM H PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11715:SF3">
        <property type="entry name" value="GLYCINE CLEAVAGE SYSTEM H PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01597">
        <property type="entry name" value="GCV_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0019986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="74" mass="8447" checksum="FEC438EDC85DA307" modified="2023-09-13" version="1" fragment="single">RLAVFLSDKGESEVKSPISGRKVSTNTAVHMDLKLLNTDPENKGWLCKIKPFDDRVKEETENLLSEDAYKRLIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0P1</accession>
    <name>A0A9P6N0P1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_003638</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000198">
        <property type="protein sequence ID" value="KAG0020756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0P1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="47"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="198"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="437"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="579"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="15"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="60"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0020756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="668" mass="75513" checksum="1747D7A9BE39AD0E" modified="2023-09-13" version="1">MKSGAPPISTISVRMPRDLATHLESPKSTQSGSLSFCAISEAKLESTKSSHDVCMPSEYGSREGSKKPLRLPSEKHEALNQSHFSGVLTSPPQGQTSPRKTAGDSSRIEMDSIGKRTTTEFFQQASIHGHADSPTLRVVTVQGGYCIDSRDCNSRISVCDEENSSMVFRQAPEYESLGNHRGSGRELNRELHISKTQLERSSNRIQGMENDHQELVSAHRELKGEMTERITSTQQQCLSTSSSFEAVMQEATKYKADVQALQDDLKDLNDCRAYLSKKQEELARSFLEIQNRRMEENQTLISQIEELKTKCELEQSLCIKQSEEAAELRQRCEGYQLSIQQLEMDTQTQAQKISELTMDLKYKDDSIKELEIALASSKSEIKTPSDSMDTKCESLISEIRVAEDLYNELAELSRKSDTATIGVSTGDDPATDLHSLMTHLQFQLDDTEAKNDDLNKTLRLLELKQVSILGEKAKLEERLKELSALSITMKDRNEDQQTQIAEAQRNYDSILKKLADSENEKARLYGSISESLAMHGTQLGSTIQECAAQFEETRKIEAIESQNQTQKIQHQICALEIKLEEKSKELGAFAKEKEKLENELVLWRAKIQLMETEKGNQQQRALKDQDENRKYIQDLEGQVRRLQDESKEASKDLPESLTQTIQQVRSRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0S9</accession>
    <name>A0A9P6N0S9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">dynamin GTPase</fullName>
            <ecNumber evidence="2">3.6.5.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">DNM1</name>
        <name evidence="15" type="ORF">BGZ80_005387</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.5"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.5" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010000266">
        <property type="protein sequence ID" value="KAG0019699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0S9"/>
    <dbReference type="OrthoDB" id="5061070at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048312">
        <property type="term" value="P:intracellular distribution of mitochondria"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030001">
        <property type="term" value="P:metal ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000266">
        <property type="term" value="P:mitochondrial fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016559">
        <property type="term" value="P:peroxisome fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08771">
        <property type="entry name" value="DLP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1240:FF:000002">
        <property type="entry name" value="Dynamin-1-like protein isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000383">
        <property type="entry name" value="Dynamin-like gtpase dnm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1240">
        <property type="entry name" value="Dynamin, middle domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022812">
        <property type="entry name" value="Dynamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001401">
        <property type="entry name" value="Dynamin_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019762">
        <property type="entry name" value="Dynamin_GTPase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000375">
        <property type="entry name" value="Dynamin_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030381">
        <property type="entry name" value="G_DYNAMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003130">
        <property type="entry name" value="GED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020850">
        <property type="entry name" value="GED_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566">
        <property type="entry name" value="DYNAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566:SF235">
        <property type="entry name" value="DYNAMIN-RELATED PROTEIN DNM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01031">
        <property type="entry name" value="Dynamin_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02212">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00195">
        <property type="entry name" value="DYNAMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00053">
        <property type="entry name" value="DYNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00302">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00410">
        <property type="entry name" value="G_DYNAMIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51718">
        <property type="entry name" value="G_DYNAMIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51388">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="4 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynamin-type G" evidence="14">
        <location>
            <begin position="22"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="GED" evidence="13">
        <location>
            <begin position="687"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="514"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="567"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="569"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="591"/>
            <end position="608"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0019699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="774" mass="85689" checksum="A70AEDA9DBB62CC5" modified="2023-09-13" version="1">MNDLIPLVNKLQDVFNTIGSDQIDLPQIVVVGSQSSGKSSVLETIVQKDFLPRGNGIVTRRPLVLQLVNTHIGSVPSSSDSTPSDAPDRAEFLHLPNKQFFDFEEVRKEIEAETARVAGQNKAISRTPIHLKIFSKNVLNLTLVDLPGVTKIPVGDQPTDIEKQTRNLILDYILKPNSVILAVSPANVDLANSDSLKLARQVDPEAKRTIGVLTKLDLMDAGTNSLDILSGRAYPLKLGFIGVVNRSQADIQSNKPMAEAFKSETEFFHSHPAYRAIAHRCGTTFLAKTLNTILMNHIRDKLPDIKAKLNSLIGQTQQELTSYGDPSFTGKAHRGTLILQLLTKFASDFISAIDGTSADISTKELCGGARIYYIFNNVFGSALDSVNPCENLSVQDIRTAIRNSTGPRPSLFVPEIAFDLLVKPQIKLLEFPSLRCVELAYEELVKICHNCGGKDLVRFPRLHAKLIEVVSDLLRERLGPTSDYVESLISIQRSYINTNHPDFIGGGGAMSALERASQKKKKDIDRSRRLSGVNTALAGNGIESSSNREENGEKVVTAAMNNLTVQAAERGDRERERERSSHPIQHGGPNSGSVSSLNGSPHGSNAGSKDTFLNYFFGGPQQHQQRVDRPSVQENPNRSGNIHSIAKEMVMPKTVLDGEPLDFDRKLDHMTDNEEFSNLNEREDMETQLIRSLIVSYFNITRKSIQDLVPKAVMHLLVNYSRESVQNRLVAALYREELFNDLLQEDDNLCAERAKCQAMLDVFKNAFTIINEAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0T2</accession>
    <name>A0A9P6N0T2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_005721</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000281">
        <property type="protein sequence ID" value="KAG0019513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0T2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0019513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="262" mass="29322" checksum="429614C5C8AA7113" modified="2023-09-13" version="1">MLVAHLCLALESHTSREYVEKAASRVSSWVNFVRIPAGEKIRLGSDTLSISSSQPSKVYGSKTIRNTKKEGRKSRFLRGRIDHWELEKGNWAERDLNSFEPLHLQSCQQLELRGEPCLHNLSRVHYWSAAKESQVLQSKIVNEVARVRPIWVNIDSLHPNYTPLLPELESPSATTEISTFNSAISALPTSPSVYIGNDSSESQTLTESLRGIPSTVSVVSLLDVDSDKNESNYTDHVNGFNGDQYVPAVFGSWLQEMELLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0T3</accession>
    <name>A0A9P6N0T3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Rho-GAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003214</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000184">
        <property type="protein sequence ID" value="KAG0021009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0T3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45808">
        <property type="entry name" value="RHO GTPASE-ACTIVATING PROTEIN 68F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45808:SF2">
        <property type="entry name" value="RHO GTPASE-ACTIVATING PROTEIN 68F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13716">
        <property type="entry name" value="CRAL_TRIO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rho-GAP" evidence="1">
        <location>
            <begin position="151"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0021009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="353" mass="40029" checksum="AC8C626CC8705C14" modified="2023-09-13" version="1">MVVICACNLPDPALVDYDTILRVVLSQLEQFVENDYTVVMFSGGARYRPGWNWLFRAYGSLNRRFKKNLKALYVVHPSTWPRLILGTMNAVISPKFSAKVHYIDNLSQLARVVPLNQIKIPAAVYQHNLKFESVIVLPDSQQDIANQVFGIPLEQLMGPNGEKGLPLFIQDCIANLTENGLYVEGLFRRSPSSAMLKQVRAAYDRGSPINLAEYDIHISAVLLKLFLRELPDPIFPVTVFEKMHQQRHEDQKEITVGEFIKTDIIPQLAHNNLVLTMEVFRLLKMVADRHESNKMTASNLAIVLTPNLVRHNDVMLEIAMSGVSNKDRHSILDKSLTLGTVTRIMIESYSDIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N105</accession>
    <name>A0A9P6N105_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Arrestin C-terminal-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_005052</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000251">
        <property type="protein sequence ID" value="KAG0019940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N105"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011022">
        <property type="entry name" value="Arrestin_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050357">
        <property type="entry name" value="Arrestin_domain-protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188">
        <property type="entry name" value="ARRESTIN DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188:SF17">
        <property type="entry name" value="FI21816P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01017">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin C-terminal-like" evidence="2">
        <location>
            <begin position="598"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="221"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="372"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="680"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="920"/>
            <end position="943"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="396"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="408"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="445"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="474"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="704"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="722"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="744"/>
            <end position="781"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0019940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="943" mass="100949" checksum="8FC43887B29F4373" modified="2023-09-13" version="1">MAASRVVYPANSQFHDPHSRSASPVMVSPPPTRIRTSGIFTRRLSLTAASVANTVASSSLFGSSPPPSNSSGIYQQSSFFRTSSSSINNPAASSSSINVSSVANDINTSASSTTMGDFSSRRHRTRSTSHPPPPKYKTYRTPQLRISLQDALGNLVLSPPVMAPGESIRGQIHLELPKATPVHSIEVCLTGTVTALDGTRLGSMKTVTILDECKTVATASVTNTRTNTTRRHTTQSTGNNDEPSRGRGRRSSVTSSSAIQDRTRSPAIPIQNTIAAAVSATIAAQQNNSSRRLSTELMSRTLSMPSPYASGYNSSTLSLNRPISPTPAVFRGRRASFSANVDTPVVGGALARGSHNMSMVNISTISQFPLDDSAIEDPSTMPEAPSYDPPDYERIFTSTANERSSGESSNTNASTQSQSESTATSETAASTSSADTTAGSDYVSEPTTVSSPTDSSEDVSTNRHSRRSSRESRNGQTTSAANSSPPAEPVEPKAVLMQPGNYVIPFSIRIPANNVVSLPGSFSDPVGSISYQLKAVMRQILPSPDPYDPKALVVEPTFTSDTQLIKLIPMNDPTYMPLYNIPFETDSVRANVGHWVWSTGFMEAHAWVPKQGYRPGRMVPLVIHIVNHSDAKQVTVETTLCKCLHYGSGLSKIRAWQGHLMDSTLETLGATDLVEDGLAPTAQTSEPTGGQRHTGRRSNRNSDRNQLQTQETSMPSPPASPYGSNFPTTPTSERDGESPEGSMHGSQMASPNSMASISSQWESIHSNSSDSNNTPLTSGSINYNSESLSSVATPTVTAVPQTPLPIVQHQREKMSKSRTLINCSLAVDREIQKTILVPIPHTAGYSILNAPLLEVSYEIVIKIRAEKVYSRGIRLSVPIVVVVPEEGDLEEEEDLLVNAGLANPGDLGLAFSGDEYDLGDQGSCPPYEATAGSSSRRRSRSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N161</accession>
    <name>A0A9P6N161_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_002542</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000163">
        <property type="protein sequence ID" value="KAG0021377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N161"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="10"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0021377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="395" mass="46164" checksum="5F6968EE5B91F153" modified="2023-09-13" version="1">MLDIPELDDMICQRLERRQLAQCSRVNKQWHRIVTPYLWRDVSSIYGYYQRAAFRSMVLEDYHIQNLQSQDPNGNMNPSCRLPLLSKYSPLIRKIPSLDGLMEYLQPPNKSIRQPSQELENAQDNGLTVHDLYILSRCSSKLKKLTFRGVVTNVEDEGPEEDEEEEEREPIIRLKHKELILSRYREWDDSTEFWRWLWKRCGRVEILRVYDTGEAVESLADGILNNMPNLREIHLGRSDQYHMDLTDGDIATLLSSCLYGWRVVEIKHTANFREASKAALFKLFPTLEVLILGNDDLKNEDLVLLLSSAPKLQELVTLDDGYYRHRNPTSIRADLLIDLDPDKTNTLRTWPCEESLKVLKVVISGIGRADLEKQRRYEITKENSMIMLRIINWTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N162</accession>
    <name>A0A9P6N162_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_005096</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000253">
        <property type="protein sequence ID" value="KAG0019913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N162"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF87">
        <property type="entry name" value="SIDEROPHORE IRON TRANSPORTER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="36"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="104"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="161"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="198"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="243"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="277"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="308"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="355"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="381"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="411"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="443"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="514"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="39"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0019913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="562" mass="62018" checksum="6E26D29418C1805F" modified="2023-09-13" version="1">MGAENDTNNLEVKGEVTEPQPPSKILDRSLFTRRQYMFLVVGVMIQAFVYSFEVNLMYNCQSKIVANFNSSSLISVLPVILQTLSAALVPFYTKVSDVVGRAQSLTFAMVFYLIGYTIQGTSNSFLQYALGQIAYGIGSTGMLTLTQVLIADTTRLINRGILFALWDLPSAINVFTTQPLTDPLTDVASHPNANWRNVYAIVGSLALVGSIALLVPLWYLQKKTEKKGYKAPRRSIGWLLHEYDAIGALLITAGMSLTLLPLILANSYERNWKDARILSMFCTGVVCLALLVFWEAKFTNKPIMPMRIWANSTCFGGLVVGFFMTVMAAMNWQYYTLYLVISRDLTFGRALLLERGYQVAYLVFQLFTGFLMRRFNTCRPFIWAGIVVHTAGIGMMIPARKPTSSDAFVVISQTIVGAAGGMANIASSVAVTGAVARKDVSTVIGVTQILGSFGSAFGGALAGGVWTQYLPSRLERHVTGPYDEYQAMNNPVYISSLDSTTKGQIIEAYSDSQMLMSIISMSLAVFACLCTIAMRHVDLRNNHLMEEQDMEVEVEGEKEEKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N199</accession>
    <name>A0A9P6N199_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Amine oxidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_004725</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the flavin monoamine oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000238">
        <property type="protein sequence ID" value="KAG0020135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N199"/>
    <dbReference type="OrthoDB" id="5046242at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.660.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050281">
        <property type="entry name" value="Flavin_monoamine_oxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10742">
        <property type="entry name" value="FLAVIN MONOAMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10742:SF386">
        <property type="entry name" value="LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amine oxidase" evidence="3">
        <location>
            <begin position="15"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="Amine oxidase" evidence="3">
        <location>
            <begin position="659"/>
            <end position="693"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0020135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="697" mass="77729" checksum="B8321A5E426E73D2" modified="2023-09-13" version="1">MAPAKKHVVIIGAGISGLAAAHELSKHPSTIQVTVLEARNRIGGRLDTHRNLVPGEHGDVPIDFGASWIHGVDPSNPIVSLAEAANARLEATNSDVIYYHPGQEAIKEDESNHYWTVLLDIYERAQEYSKANRKHIPINTSFTNWLNNFLSTRQCNDPQLPNYMSPKEFEIVPLLAQFWADENAIPLNKVSLKYMDAENMLPGDHCIMANGYDGVLDVLCKDMNSVDIRLEHVVNRIDYNESNVKISTNKGMFTADVVLVTLPLGVLKSNSVTFSPPLPERKRTAIKRLGFGTMVKAVLYFPTCFWPADKHFINFLPIPSSIPNPKICRHLNRRQMKALKTYMNDLANYTSLMPIHGAPILIAYMANDSAEVFEKLTEEEAMEVLVCQLSHYFDVLAKDPAKFKPTRTFMTRWNADPYARGSYTSIPVGAHQSDLAEFEIPVGARSVVVGGATEERKKKGEARKAYKIDELVVENAWRTNNNAVSRVNSTRSAKATNVSRIDKLDGLSGSIVIKNHNTVNLSDSISYFNQRINHAFADNSRRNVWKNGNKTHNSQLSVIGIKGRGLFPRMNDVGYNFGYIGQHGLVNSITRDPLLIVNGSMLSRYYDDKILRIKEEHIMPLAELDPLVVCSGANPNRERMTSKKKPSTVIKTIAVDDAARGRIHFAGEHTTPTSFASVHGALMTGRREAAKILAQTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1C4</accession>
    <name>A0A9P6N1C4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Mitochondrial carrier protein ymc2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">YMC2</name>
        <name evidence="11" type="ORF">BGZ80_002249</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000155">
        <property type="protein sequence ID" value="KAG0021510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1C4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000064">
        <property type="term" value="F:L-ornithine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990575">
        <property type="term" value="P:mitochondrial L-ornithine transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050567">
        <property type="entry name" value="Mitochondrial_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624">
        <property type="entry name" value="MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624:SF12">
        <property type="entry name" value="MITOCHONDRIAL ORNITHINE TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="6"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="110"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="257"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0021510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="348" mass="36720" checksum="1C83205EEE4BBD5A" modified="2023-09-13" version="1">MSSDSIQAVKDCVSGTVGGFLQVFVGQPFDTVKVRLQTMPAPLPGQAPLYNGTLDCVKKTLSKEGIKGFYKGTTTPLVGVGACVSIQFVTLQAMKRYYNNQNGPSANGFLTNSQLYLAGAASGITNSIISGPVEHIRTRLQVQTGAAPAVKAITGAAAEKVAGSITGGSVASTAVATTGNATAVKAVAEAGAKDALFFAGPVDAVQKIYAQHGLRGLYKGQAVTMVREFQGYGAYFAAYEYLVQRAMRLENKQRNELSTVKFVAYGACAGYAMWMTVYPIDVIKSKLQTDGFTAATRQYSSAMDCARQTLAKEGVAGFFKGFAPCILRAAPANAVTFLGFELAMRVLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1N9</accession>
    <name>A0A9P6N1N9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Eukaryotic translation initiation factor 4E type 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">EIF4E2_2</name>
        <name evidence="3" type="ORF">BGZ80_004105</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic initiation factor 4E family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000213">
        <property type="protein sequence ID" value="KAG0020502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1N9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016281">
        <property type="term" value="C:eukaryotic translation initiation factor 4F complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000340">
        <property type="term" value="F:RNA 7-methylguanosine cap binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.760.10:FF:000043">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.760.10">
        <property type="entry name" value="RNA Cap, Translation Initiation Factor Eif4e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023398">
        <property type="entry name" value="TIF_eIF4e-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001040">
        <property type="entry name" value="TIF_eIF_4E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019770">
        <property type="entry name" value="TIF_eIF_4E_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11960:SF18">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4E HOMOLOGOUS PROTEIN, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11960">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01652">
        <property type="entry name" value="IF4E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55418">
        <property type="entry name" value="eIF4e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00813">
        <property type="entry name" value="IF4E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="1" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="31"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="80"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="95"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU004374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0020502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="313" mass="33160" checksum="A57E49EB27E52864" modified="2023-09-13" version="1">MESAWGPRKSTRATGENPPTSGSKLVQLQRQSSPAGSALSSSSTVSTPSTVASQSQPSIAGGALDFGTRADSSHHTNSKVAAGSGSSNASPASGGVAGAGSGSGSGNGVSAVGVTASAVGTVATPTSLVSSGSLHPLHFNWVFWFMHRAPGSKILNYESSMKKIATFGSVEDFWAVYSHLKRPHELPTVSDYHLFKQGVRPVWEDATNINGGKWIVRLKKGLASRYWEDLVVAVIGDQFDVGSEICGAVLSIRGGEDILSLWNQSAHEGRINLKIRDTMKRVLNLPADTIMEYKTHNDALKDNSSFRNTDVFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N221</accession>
    <name>A0A9P6N221_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">peptidyl-tRNA hydrolase</fullName>
            <ecNumber evidence="1">3.1.1.29</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">PTRHD1</name>
        <name evidence="4" type="ORF">BGZ80_003416</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>an N-acyl-L-alpha-aminoacyl-tRNA + H2O = an N-acyl-L-amino acid + a tRNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:54448"/>
            <dbReference type="Rhea" id="RHEA-COMP:10123"/>
            <dbReference type="Rhea" id="RHEA-COMP:13883"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:59874"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:138191"/>
            <dbReference type="EC" id="3.1.1.29"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.29" evidence="1"/>
    <dbReference type="EMBL" id="JAAAID010000190">
        <property type="protein sequence ID" value="KAG0020884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N221"/>
    <dbReference type="OrthoDB" id="201213at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004045">
        <property type="term" value="F:peptidyl-tRNA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1490.10">
        <property type="entry name" value="Bit1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023476">
        <property type="entry name" value="Pep_tRNA_hydro_II_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002833">
        <property type="entry name" value="PTH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042237">
        <property type="entry name" value="PTRHD1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46194">
        <property type="entry name" value="PEPTIDYL-TRNA HYDROLASE PTRHD1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46194:SF1">
        <property type="entry name" value="PEPTIDYL-TRNA HYDROLASE PTRHD1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01981">
        <property type="entry name" value="PTH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102462">
        <property type="entry name" value="Peptidyl-tRNA hydrolase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00048707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0020884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="121" mass="13589" checksum="F8F63A4CFA02074E" modified="2023-09-13" version="1">MADPLTMFIVIRKDLIKTLGWTTGSVIAQACHASTAVLHKTQDLKDTREYLADLNNMHKVVLEIKNLPQLESLSASLSALDVPHVTWKEQPEDILTCLSTSPIRRSPEVKEAFKKCSLFRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N261</accession>
    <name>A0A9P6N261_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Heat shock protein sks2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">SKS2</name>
        <name evidence="4" type="ORF">BGZ80_003164</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000182">
        <property type="protein sequence ID" value="KAG0021043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N261"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10233">
        <property type="entry name" value="ASKHA_NBD_HSP70_HSPA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000002">
        <property type="entry name" value="Heat shock 70 kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000172">
        <property type="entry name" value="Heat shock 70 kDa protein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000026">
        <property type="entry name" value="Heat shock protein 70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.30.30:FF:000005">
        <property type="entry name" value="Heat shock protein ssb1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0346">Stress response</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0021043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="418" mass="45669" checksum="F32F8F2E37AA5A46" modified="2023-09-13" version="1" fragment="single">MSEVTDLAIGIDLGTTYSCVAVWEGERVEIIANEQGNRTTPSYVAFSEQERLIGDAAKNQAAMNPTNTVFDAKRLIGRRFDDPEVKSDMKHWPFTVIEKDTAPFVQVEYQGEKKEFSPQEISAMVLVKMKEIAEAKLGKTVTKAVITVPAYFNDAQRHATKDAGAIAGLDVLRIINEPTAAAIAYGLDSKETKEKNVLIFDLGGGTFDVSLLAITGGVFAVKATAGDTHLGGEDFDNTLLEHFKEEFKRKHKKDISGDARATRRLRTACERAKRTLSSLAQTTIEVDSLFEGVDFQANITRARFEEINSTHFNNTIEPVKKVLKDAKFSKKDVDEIVLVGGSTRIPKIQSLLQEFFDGKELNKSINPDEAVAYGAAVQAAVLTNQAGNAKTQDLLLLDVVPLSLGVEMQGGVMAVVVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N268</accession>
    <name>A0A9P6N268_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_002681</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000167">
        <property type="protein sequence ID" value="KAG0021312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N268"/>
    <dbReference type="OrthoDB" id="1669814at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43639">
        <property type="entry name" value="OXIDOREDUCTASE, SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY (AFU_ORTHOLOGUE AFUA_5G02870)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43639:SF1">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0021312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="254" mass="27335" checksum="66585DBE7E27B48B" modified="2023-09-13" version="1">MSHAATPQDLVGKVAFITGSAKNMGQQFALALARRGCDVVIHHRNNPEEAEKTSQEIQALGRKTLVVRGELTSVSMIENIFAQILSTFGHIDIVINNAGMVLKKSITEISEHEYDQCFQINAKVPFFVMKECAKHMADNGRIINIGTTLLAITTGGYSVYAGSKAPLEDFTRAVAKEVGSRGITVNTIAPGPIDTPFFHGQETKESVAFFSTLSVAGRLGTVNDIVPVVEFIASPGSQWITAQTIFVNGGVIAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N294</accession>
    <name>A0A9P6N294_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001490</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000134">
        <property type="protein sequence ID" value="KAG0021896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N294"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="264"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="294"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0021896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="399" mass="43651" checksum="E220A32B39AECDF9" modified="2023-09-13" version="1">MARSSAGSGTFVNPYIAYVAEIDPDGTMDDGRAYVGGAAHYVDKPQTKSKPPTSSNMKTAPLSSKPSTTAVQNQGSFKQSGPPTGSSGRHRPGRLERGFADSRWSGQALATAADMLPDGFFGTAKPAVTSSQRNPSRYEDSPRTEPPQTPKTWQAQSNEWGTWGKQPQSGSIPQSESRNPPPQPHQYVSRTQPEPRDSSQLDDYQRGASWDQPEPASMTSQENSTDLYRAKQAPETVPPNPSGHENEYIRTQTSMSRSQPVDQSFGSSRRGSMRSTGFPSQGYAYESDSESSSTFRSQLTSLSRDATQKPSVSSMSNIEPLEQTPPQNQGNPLFLQYPIGDGCHAIVAIYVEKDAQSAVRRFPGIERTRLESSRRDKTLDEMAVIFKEALEDEKKSLIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2E6</accession>
    <name>A0A9P6N2E6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_011436</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000092">
        <property type="protein sequence ID" value="KAG0022701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N2E6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="3">
        <location>
            <begin position="15"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="1">
        <location>
            <begin position="15"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="81"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="146"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="205"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="163"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="205"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0022701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="363" mass="40523" checksum="5057A97DCA4326BF" modified="2023-09-13" version="1">MSAEPKGNAPAPLDPFGNEVCLLFLKYGKCRYKKKCKKSHILPDKNAPIMQKVTEFVAEQPAVKTGPKVAFSVRMMPYAKPSPTAVKPQTQKLRGVTGRPDHGSSQHAQSTSVNISNLSTGMEGVDQTIVPVSSFPSADIALVVKEDSQDTVPKDQQLPERVKQKKPKPKRPPKVPSKCLLASLFRTNIPSPEVRPAVGTFVIGQPQTRTKALQSTNSSTNPTRKSRLRSKSKPTAPVATSAFSTNVSEASSEKIEQWYITNKAHLENVPESMPGGGGTPRRRLMVLNKPTTARQKSQLKIMRKHHWECRLEVEYNLKRNLPAIFSLKIARTKIDWEKVVPYVTLMIQASLELRYVYYWNREA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2G2</accession>
    <name>A0A9P6N2G2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Crinkler effector protein N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_000994</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Host cell</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000122">
        <property type="protein sequence ID" value="KAG0022125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N2G2"/>
    <dbReference type="OrthoDB" id="2409492at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043657">
        <property type="term" value="C:host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045379">
        <property type="entry name" value="Crinkler_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20147">
        <property type="entry name" value="Crinkler"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Crinkler effector protein N-terminal" evidence="5">
        <location>
            <begin position="30"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF20147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0022125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="125" mass="13695" checksum="7FB29735E8CB6956" modified="2023-09-13" version="1">MSSKRKASEQTVSNPETTSETGVRYSSALLKLNCIIVENKSSSFPVEIHSDENVSALKRGIKKEKPNYLSSIDANNLILKLVPEGGKTKAGLFSSSLEVLDDELVKLSTYFPENPADDLIHIVVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N324</accession>
    <name>A0A9P6N324_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD/NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_001417</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAD-dependent oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000132">
        <property type="protein sequence ID" value="KAG0021933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N324"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004174">
        <property type="term" value="F:electron-transferring-flavoprotein dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43735">
        <property type="entry name" value="APOPTOSIS-INDUCING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43735:SF3">
        <property type="entry name" value="FERROPTOSIS SUPPRESSOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="5">
        <location>
            <begin position="7"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0021933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="399" mass="42137" checksum="4CF64C11A7028D03" modified="2023-09-13" version="1">MSSEPVKVVVVGGSFAGISVIKQLLSSLKSSKKQVQITLVEKHDARYHSPGAFRALVDAEYGDKIWVPYTSLFPKDSGHRVIKDTLAQVYHHHIVLGSSGTVPFDYLVLCTGSDNPASGKFNNVSSSAEAVAITSKARSDLTKSKSVLVVGGGASGVELAGEIKNAFPDKQVTLVHGGPRLVDYEGYASGLKSYSLKHLQGLGVKVVLDQRVAIDGLDHEHSIHVGQSTITTKSGETIQSDIQLLTVGSCVNTSYMSTLKPKGDDAFDSSSLVHNDTHAIKVQKTLQLANESFPYIFAVGDCSDFSNVPTAASAAFSAPTAAKNLIQLIETSSSDSGKKAKLGPASGAPAFMILATGPNTGVSSLPLFGTRFSNFFAKLLKSKDLMIGNVYTEMGVSPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N396</accession>
    <name>A0A9P6N396_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_008793</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000049">
        <property type="protein sequence ID" value="KAG0023621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N396"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040392534" evidence="2">
        <location>
            <begin position="21"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="105"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0023621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="234" mass="25088" checksum="82F8CEA3D3C86056" modified="2023-09-13" version="1">MGLNVSVLSFFLALVEMLRAIKDIPLPFHIHVEGGSDEEDEDVVTEGDNNDALRSGSVSFDIGSQAEAIAEGSGLGPNAAASTAATQRKQSRTQPPSATRGPTGRSSSQASIRSTTSSGQPDISYGLRRSTTFVDDAMVEAGFGDDRREQLSAASKFYNRRDFDSKIEGSADGMFRLRRRSTVSTPQQAGLGTGSHNVGTRPDELVGNIPRRSIKNSIFSRKTNTDDDTDTDEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N473</accession>
    <name>A0A9P6N473_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">E2 ubiquitin-conjugating enzyme</fullName>
            <ecNumber evidence="1">2.3.2.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">UBE2G1</name>
        <name evidence="9" type="ORF">BGZ80_009987</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.23" evidence="1"/>
    <dbReference type="EMBL" id="JAAAID010000065">
        <property type="protein sequence ID" value="KAG0023252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N473"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd23795">
        <property type="entry name" value="UBCc_UBE2G1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000025">
        <property type="entry name" value="ubiquitin-conjugating enzyme E2 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="8">
        <location>
            <begin position="4"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="6">
        <location>
            <position position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0023252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="165" mass="18742" checksum="7C911FABB6CBC0AF" modified="2023-09-13" version="1">MSDQSTLLLAKQLDYLGKNAVEGFSAGLVDESNIYEWKIMIMGPPDTLYEGGFFEAIMTFPQDYPLMPPKLRFITNIYHPNVYPNGEVCISILHPPGEDKYGYEKASERWSPVHTVETILISVISMLSSPNDESPANIEAAKEWREDYPSYKKKVLKLTRDTMGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4D0</accession>
    <name>A0A9P6N4D0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7721 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_009459</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000057">
        <property type="protein sequence ID" value="KAG0023420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N4D0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056138">
        <property type="entry name" value="DUF7721"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39477:SF1">
        <property type="entry name" value="BETA-FLANKING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39477">
        <property type="entry name" value="CHROMOSOME 8, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24845">
        <property type="entry name" value="DUF7721"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7721" evidence="2">
        <location>
            <begin position="19"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0023420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="185" mass="19189" checksum="DAA22A5E2CAC77F3" modified="2023-09-13" version="1">MEMIQELAMAKLKEKMSGAGHSDEDVEVMHESVQKVKVSGVQPASEDEIDEAKAAHEKVYKQGNTDEASDEELGKAAGVQAYHEYKKAETESEEDGEEGGGQAQLMQMAMSEGMKMFSGGGGQDKGVVIQSAIAMAMKLFMSQGGLEKIMGMMSGGGEGGGIGQLMGALGGGNGGGVASLLGKFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4K8</accession>
    <name>A0A9P6N4K8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_001718</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000014">
        <property type="protein sequence ID" value="KAG0024526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N4K8"/>
    <dbReference type="OrthoDB" id="186625at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048306">
        <property type="term" value="F:calcium-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd16180">
        <property type="entry name" value="EFh_PEF_Group_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051426">
        <property type="entry name" value="Peflin/Sorcin_CaBP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46212:SF3">
        <property type="entry name" value="GH27120P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46212">
        <property type="entry name" value="PEFLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="32"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="106"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="23"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0024526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="212" mass="24532" checksum="4B3771B93E3F1756" modified="2023-09-13" version="1">MAYNQNYQQQPYGQQQYQQGAYQPPPTAPPQTPEASLRYWFDAVDSDHSGQLSTEELQRALINGDWSPFNIETVRLMMNMFDTGKFRISSDNSGLITFPEFAGLWKYIEDWRSCFQAFDRDRSGYIDFSELKTAMHSFGYNLSDNFLQLIIKKYDKRGKNPQGRGDVSFDNFVQIAVTVKSLTDAFKRIDREGKGYATIAYEQFLELVVSNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N6V5</accession>
    <name>A0A9P6N6V5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BGZ80_006073</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000003">
        <property type="protein sequence ID" value="KAG0024800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N6V5"/>
    <dbReference type="OrthoDB" id="9944568at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005385">
        <property type="term" value="F:zinc ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098771">
        <property type="term" value="P:inorganic ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030003">
        <property type="term" value="P:intracellular monoatomic cation homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="entry name" value="Cation efflux protein transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027470">
        <property type="entry name" value="Cation_efflux_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036837">
        <property type="entry name" value="Cation_efflux_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058533">
        <property type="entry name" value="Cation_efflux_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050681">
        <property type="entry name" value="CDF/SLC30A"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11562">
        <property type="entry name" value="CATION EFFLUX PROTEIN/ ZINC TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11562:SF17">
        <property type="entry name" value="RE54080P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16916">
        <property type="entry name" value="ZT_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160240">
        <property type="entry name" value="Cation efflux protein cytoplasmic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="Cation efflux protein transmembrane domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0864">Zinc transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="241"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="274"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="311"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="342"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="381"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="415"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="445"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein transmembrane" evidence="11">
        <location>
            <begin position="242"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein cytoplasmic" evidence="12">
        <location>
            <begin position="480"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="11"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="58"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF16916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0024800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="592" mass="64386" checksum="4580A8107E379A9A" modified="2023-09-13" version="1">MVSKKKRTAKSKSSASLQAQTSAKTSSSPSPSASSSLAPALTPSTVSVSDSVSVSVSAQPAQALQSLQENKDVNDNNDNNNNNGSNDSNGNNEINDNNDDEHQPLLQPEQPLHSRNPHRSPTLPHQELTNNGSDHSQSQAHSHEHEHDHHDHHDHHHEHGNGHSHAPQGIVDSQSIIHTSAKSTTPLKQSLTQSYGSTQGTVVVDIEDSAHSTPLRSVSPPPIACKGVLITSETTKSKRKLIFVTILCLCFFAVEMIGGYFAKSLALMSDAFHLLSDVISFIVSLIAIWLSEQPATKRHSFGYHRAEVLAALMSVFIIWILTAFLLMEAVERIRNPQPIDGKTMCIVASIGVVLPLLWDMIMDTTMDMDMDMTTATGMDMITVMNTTMAMTILMSTAMVPLTPTPTVEININVKAATLHVIGDLISSVGVLVASIIIMIKPSWTIVDPICTFFFSILVLFTTYRLVWDSLGILMEGTPTHIDPEEIESSLLEIPGVTLVHDLHVWNLTAGKPSMAVHLQLAPTSHLTNQELTMVDYDRILAQAQNVVCGRFQIHHSTIQLETASNSSEHCRPDICSNEPLSAAAVGRGNNVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N7I4</accession>
    <name>A0A9P6N7I4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA-dependent protein kinase catalytic subunit CC3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_003699</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000002">
        <property type="protein sequence ID" value="KAG0024840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046804">
        <property type="entry name" value="DNA-PKcs_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046803">
        <property type="entry name" value="DNAPKcs_CC1-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012582">
        <property type="entry name" value="DNAPKcs_CC3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045581">
        <property type="entry name" value="DNAPKcs_CC5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20500">
        <property type="entry name" value="DNA-PKcs_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20502">
        <property type="entry name" value="DNAPKcs_CC1-2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08163">
        <property type="entry name" value="DNAPKcs_CC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19704">
        <property type="entry name" value="DNAPKcs_CC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01344">
        <property type="entry name" value="NUC194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA-dependent protein kinase catalytic subunit CC3" evidence="2">
        <location>
            <begin position="1665"/>
            <end position="2072"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1897"/>
            <end position="1948"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1899"/>
            <end position="1913"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1925"/>
            <end position="1946"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0024840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="2301" mass="259266" checksum="582BBBDFFF6DA1CC" modified="2023-09-13" version="1">MSSPLDLIRLTLVELIDEMNGENPDNVDSQAAATNICNMALTDLKDDEIDMAISLLFNPDKGIMYFLRKALDKTAHGAAKVTFLEFTAEFISRSPNSITPHIVDIKRTCLALFLNDSMARIKKSSILPIKILLSSCNKMIDPEALDVNGLFEKLYEAYGSQQSKMASTVKAEVLEVLGIIARYFPKVAERRQAMLMRWCLTTITDQLRPGAKQELVLVAGALVGLDNCLYNFSDKAVKDVPAILQLIKTLVNVPEDLSRFATPVAALDLFAHHIHLFRSKLIEIYEWMYQRIAGYCEHSHAGMSKCGYNSLDVFLQEMASVLTESETTEREYNCFLFFTTNFTQIISTEVISSTAQYKAMSVAIRGYGYFAAPCKHIAPDLLKSLLAQLLRKSSFLVSSNTNEGIDGSSSHLAAFITAYTCVAQVYDEIPELLVTALNQMANAAVVNFTKMSIYARIDCTIAIERLLVMLFHKGEGVLRSFFDKFSYKLLVFTAADISKPTTGGFRGGQIMVVEDANWHSYAVYLFLWRNLFKPTALSVELDKTRIVISDENLERFLRIIYGSTMESFKRLVSLLNLSVSDSEMNVDDEAMQGIKIEDVEQAKVSATGPVSGDVAKMQANCAKDFIIFQNLTEFWQIFLPEIRPDLFARWTFVIGNTLIELSSRHPFVSGFYKMFATCLQVCQSISLFQQKDGPKSKKTDSEPVDTQRAAALFQKYIREVLARLEQYKDDLLASCLQLVLSSPSALTDSSSIIPPIQLALKLGLGYLPLATVGLDAIERWIDIVDDDDDSWLSQVLPCLNEYLMVQVTVAGDNDAIDGSTTKSKRKTLTRQNQSYRAIAKTASMLTSSETVQSLRNLQLRILRLLGQQARHNKLILSQRAIQDNSKKESSDLLAWDPEPRLKLKIPFQEMKTELQFDEMLPRIVDLAENSLNRQIKVASCELLHSLMILMVGSSAFRARDAQEPKKSPFHKIFLKVFPALLRLAVDVDQVPRSLYRPMVSQLIHWLTNNAQYENPETIALLNACMDAACDTLGPLRDYGAECLGEFVKWSIKQSSTSSSSGSVNVKSLLKRIYNLASHSNPAKRLGASLIVNRIYRVFREESTLVNQFTMELLYWMLFSLKLAESDHVGLGTRQQACLAITHLQRIIQVKAAVFIKDSKERASTPGAWIGAKISQNSAFLSTVYSGAVYNAETLSQPIAYQKWCSQLATLLSNYIWLLNHPGNSELLMTQLKSTTIFTSSAKFLETCLSFSRALVQGQMAMPLTPLERRQAMDQNFITVRKVISFVSLVVTRGSDRGSGAMVEHLKASGVIGSKFFEVFAACLFNPDSIGDDELLKSEEEAKVLKGELEIGLVMLHRLSPDVSRSFGEVLMGTIASGDLIPLAISPGANGNAVFSYGLDPENAENAKMTYLKYADEINRHLAMCFSELTPVLSRSAKKSTLVLTIWNDFLDYMFSHPELSVERSTFLDMLTMDFSVLKSISELLDRDQVSMTITIWKRIVALSPRILRMSKSDAFVDYFFEVFQSFFERDLEKREYLTLPVMSEAFPILPIFLSYPGARTAEFETVFSRAILNLMPMSSSEYERGSSKFKDYIAALDLLFKASVASSSTSLFKTLMGIAIRESNHAYMEQMQQYISSFALKLPLSKFLEITGHCFDAFIKRTHSDEHRRNIVHQILLPILKIVPPLSVSEFYVLHISKIMSVIKQDQPRLTDIEIRRDFIERECCYDLIHVLYMRLPSDLVNSKESKIVDAFTNGKTVTGKELTVDVFRTANAAKFKQDTNSFTPEASVLREGFKRAAYNALAAAILCTQRKEDFFRQFLFRDNEAKKEFVWENIVDLTAKYHFEQVFSGPLVKTKLSDLRSKSLNPNRMFKSEYQYMSSQYLRDSSLSQSVGMVDDSNVISDTDNGSSNQDDASLESESFIDATESKAIDGKSDKKSDEPEHTLELDSINSNPCMKMILLIIKELHTSITPPPKEMAKEESTMPSWMKDIHRKLINPNAALNVRLFLAKIIINMPEAFEMYAHSWIRPLMKLAMEGEAYGEAMNYFVQDLCVLIVVWGESVKLTNTYDDRVLLLSFLSYLMKNCHCEQRQYLLNNIDLIKGVFENWSSIAIVPTTIIYNNFKNIKDDKKNVTGIQLLGIVLTHDNPPFYKGPEIDLGTLNEADYYEALVRNMGSSLSKVYTSAAEVCGLILAYMKRHNCMDIDFQDLVTKKLSELLIVKSGSNTRSKSGTVQFLNSLHKVQINFPEITDAFGPRLLFLFPQLLGEERKMALEIFASRAAYLPDLFQSLQGLNFLGCLKHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SQQ3</accession>
    <name>A0A9P6SQQ3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_009094</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010005192">
        <property type="protein sequence ID" value="KAF9991480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SQQ3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9991480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="127" mass="14318" checksum="6E9C20AB1E90F9E9" modified="2023-09-13" version="1" fragment="single">MDKRKLLPSSNKEPLKCSTICLVGQTRPLESKGYQYNNNSLCTFEGTLLANKPVYIVAFMTAENTICWKVFEHLGQETGKNHNNFRSSEWGPEAADVMCKEVRDYPAVRGLKVGDLIDATPKEFICK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SSA4</accession>
    <name>A0A9P6SSA4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007607</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003920">
        <property type="protein sequence ID" value="KAF9995113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SSA4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="211"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="226"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9995113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="267" mass="31120" checksum="EC15A61488A5C996" modified="2023-09-13" version="1" fragment="single">MAVAMQTKKKLKDRTRQRRAFEEEDEDMVIISRLENEPWQPDLLLERQSDKINHIDHPDQRYMAHQSSPYSPLTSLTAPTTDSTTNAKANGSSVQQSSGFQGVIPVIIKSPSSVITTVDSDEDIFEDHAPKMPGIEEYLQQTHQRQQLLQQQQRQQQQQQQQQQEEMQMQMQLQLQYQMPAHLQTNNASNNFNNRRQQSRLHQDLVPQQYRNSFHGHTGTSHFDMEKEDEDEGEEEERPILQLRSLSVHEPSIRSESPMEKVMSDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SUQ1</accession>
    <name>A0A9P6SUQ1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005407</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002668">
        <property type="protein sequence ID" value="KAG0005681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SUQ1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0005681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="147" mass="15809" checksum="A34A4E1960D24A2C" modified="2023-09-13" version="1" fragment="single">MDVATSNGPKTKATSAIGKARERKVAVKNDSDVDEDESDENVDELTRNSAPTKIKPHDPTLPVVEGVEGVEGVEGVEDVEGGSELLRTKFRRTKSKIIGTSTALAPSKNKTKASSATGNLQAMSQRKLPHCVLSRLRRSTEKRIPGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SV31</accession>
    <name>A0A9P6SV31_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fumarylacetoacetase-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_005464</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002696">
        <property type="protein sequence ID" value="KAG0005290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SV31"/>
    <dbReference type="OrthoDB" id="74910at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018773">
        <property type="term" value="F:acetylpyruvate hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.850.10:FF:000003">
        <property type="entry name" value="Fumarylacetoacetate hydrolase domain-containing 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="entry name" value="Fumarylacetoacetase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011234">
        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11820">
        <property type="entry name" value="ACYLPYRUVASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11820:SF7">
        <property type="entry name" value="ACYLPYRUVASE FAHD1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01557">
        <property type="entry name" value="FAA_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56529">
        <property type="entry name" value="FAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fumarylacetoacetase-like C-terminal" evidence="3">
        <location>
            <begin position="12"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0005290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="222" mass="23923" checksum="DFDAC7A77EE3CF1F" modified="2023-09-13" version="1">MAARNFIHSGRKIVAIGRNFSEHAKELGNAVPKAPFFFLKPTSSYISNGQNIEVPSGCEVHHEVELGVVIGKDGRDIPASKANEYIAGYTLALDMTARNLQQIAKTQGLPWSAAKGYDTFTPIGELISKDQIPDTNNVDLSLKIDGVTKQNGNTRDMIFKIPNLIEHVSSIMKLQEGDVILTGTPAGVGPVLPGETVTCELGTQGKIISQLKFGVVDRPKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SVP1</accession>
    <name>A0A9P6SVP1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transcriptional activator of fatty acid utilization</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">CTF1_2</name>
        <name evidence="9" type="ORF">BGZ80_004846</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002427">
        <property type="protein sequence ID" value="KAG0007290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SVP1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051615">
        <property type="entry name" value="Transcr_Regulatory_Elem"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313:SF81">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="8">
        <location>
            <begin position="131"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="505"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="641"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="510"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="682"/>
            <end position="696"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0007290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="799" mass="88121" checksum="52C2596241596286" modified="2023-09-13" version="1">MTGYLYIPENKDDTLILPSKDVIDHLMGVYFHSIHPTLPMLHPQTVSDQIHRNESPPSHLFFAMMGLASRFSDNDSYRVPQPGMVCPPSAIFYERARHFIKEEYDMPHIATVQTLLLMSIQQMGFCENKTAWLYVGMAIRMAQELGLNKEPSDQEQSRNRLQCELRKRTWWSVYVVERLVCVGLGRPLSVTRKDCEASFPTYEDDEGDEASGKMHTMDISNFVQLIRLSEIQGSILEFVKTKFSPHGRQPSLNLDSDQDRKIDTSAARFAELDKSLAEWRQNLPESLQNPSAQSPRLHFFLHMIFNTLIILLHRPEVPTSHTSASLCAQAAATISDYIEILMETKVLGSMFISCIYAIFSAGLIHFMNIPSVHKPTIPSTFNPALPELNESHSSHAKTAKTSLKRCIDALKVLSGHWLSAGRRAKVLEDLLDLKHVSLKDLEVDTFRTSPVGPSWVMESQYKEVLVQPAKNQDKLRQRCRSKVMAIQSLLGSDDDFAKMHSRNSFVFPDHNADNNEKNAEESTGEKTETNEDNGQKDTLMHPVKSSTDRSEMSTSLISSQAPIIGLGVQSPYSSAPSVSSSASTLTDASAVQQVSESDPGMLISTASLGISDSPAMSNGKFFTDTKVENGIAVATMVQGDASPQLASSNRTDAQGAPADGRSGTRSSGTPDLQGAMLDPFSMPSSISFPDWNQTKQSSNSNIDINMSDIASQSESQSNGAKQYDQASDIATSAPQPISLSSESSAHPFSGAKALDREEQDLVWNDMPPTLGLDEWTAYIGAMMMRWLYASGQSPSGSSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SW58</accession>
    <name>A0A9P6SW58_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Spindle pole body component</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_004217</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
            <location evidence="5">Cytoskeleton</location>
            <location evidence="5">Microtubule organizing center</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TUBGCP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002177">
        <property type="protein sequence ID" value="KAG0007794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SW58"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000930">
        <property type="term" value="C:gamma-tubulin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044732">
        <property type="term" value="C:mitotic spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000922">
        <property type="term" value="C:spindle pole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043015">
        <property type="term" value="F:gamma-tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051011">
        <property type="term" value="F:microtubule minus-end binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031122">
        <property type="term" value="P:cytoplasmic microtubule organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007020">
        <property type="term" value="P:microtubule nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051225">
        <property type="term" value="P:spindle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1900:FF:000011">
        <property type="entry name" value="Spindle pole body component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1900">
        <property type="entry name" value="Gamma-tubulin complex, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007259">
        <property type="entry name" value="GCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040457">
        <property type="entry name" value="GCP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042241">
        <property type="entry name" value="GCP_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041470">
        <property type="entry name" value="GCP_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302">
        <property type="entry name" value="GAMMA TUBULIN COMPLEX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302:SF13">
        <property type="entry name" value="GAMMA-TUBULIN COMPLEX COMPONENT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04130">
        <property type="entry name" value="GCP_C_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17681">
        <property type="entry name" value="GCP_N_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3 5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gamma tubulin complex component protein N-terminal" evidence="8">
        <location>
            <begin position="33"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="Gamma tubulin complex component C-terminal" evidence="7">
        <location>
            <begin position="375"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="465"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="465"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="488"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0007794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="778" mass="88318" checksum="C679F01AF5C81EE9" modified="2023-09-13" version="1">MSSKSHLDVDKYKQGEFQKVGTLSLKLQESSIIEDLLFTMMGIEGKFISATRPIVTAQSQDADYVHMEFKVDESLDPSLRDLVSRILPLASIYLSLEAFVELHSMFEYGFVNHALCAAIRNLLKEYLILIAQLETQFRSSPDFTLQKLWYYIQPTMQTLSSLDVLVGVIRDAGKKEPPNEDDVDIEALLNPRVGIPQERKGGSILAIIAGGMFNMSGDPVTKKLYGFLLNKASVPYISMLELWIHKGEILDPYEEFMIMESSKVKKESIKEDFSDAYWEQRYTIRDKYVPPFLVPLKTKILLAGKYLNVIRECGIHLTNEQNSATEKQASNVSGHTERNDVLAALSGGNLVETIDAAYQYANKKLLDLLLKDKQLIGRLRSMKRYFFLDQSDYFTHFLDLASTELKRPWKEVSLTKLQSLMDLVLRNPSSVTVNDVFKEDLKVDMSHLGLVDQLLRIISINGEEQGHGQDERRESRGSIRSKARTHSRASSGGAQNQLGSYDSWQDELAASAMEGVMATSTAQGKPLSGIDSLTLDYSVKFPLSLVISRKALTKYQLLFRHLLYLKHGEQVLCSTWIEHAKSPVWKNVSPELKQWRGRIYGLRSRMLTFVQQFAYYVCSEVLEPNWNNLASKLAKVSTVDQVLQIHSDFLDTCLNQCMLTNSKLLRIYSKLMSTCIKFTNYTDRFTRALTAMETQLDDEASAMAPGSQIQQIQQAIRRLSEFENGFTYHLKLLIDALNLYSATETVQFLCLVVRLDYNLFYANQSSESLNLASSAQLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWC0</accession>
    <name>A0A9P6SWC0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_004002</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ARS2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002096">
        <property type="protein sequence ID" value="KAG0007975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWC0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016604">
        <property type="term" value="C:nuclear body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031053">
        <property type="term" value="P:primary miRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025239">
        <property type="entry name" value="DUF4187"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039727">
        <property type="entry name" value="SE/Ars2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007042">
        <property type="entry name" value="SERRATE/Ars2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021933">
        <property type="entry name" value="SERRATE/Ars2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13165">
        <property type="entry name" value="ARSENITE-RESISTANCE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13165:SF0">
        <property type="entry name" value="SERRATE RNA EFFECTOR MOLECULE HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04959">
        <property type="entry name" value="ARS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12066">
        <property type="entry name" value="SERRATE_Ars2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01173">
        <property type="entry name" value="DUF4187"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="561"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="257"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="691"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="693"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="724"/>
            <end position="734"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0007975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="755" mass="85969" checksum="1182328FEA16628A" modified="2023-09-13" version="1">MPKDYYRGDYSDDESSSRGRDKFRRERSPEKDDFGRDKRRRKTSASPDDRERRPRRNRSSSKDGDGDPGDRYIPNYERDGYNPAPRYSRPDHFGNRYDSPGGYGDYRGQRRRDDGYGDMDGPDPMPYGDMSLGWGNADRVDDPMKLDHLISFKQYCEHLRNVDRASHRYKRYTDEELQARYGTYKEEFTAKQYAAFFDAHKSEAWFQEKYHPDLSIARTEEAQTLRRVRYGKFIEDLAAGKYDNTTCDEAEAKKASAAMTETKAEKSDADGESAEPTDKDGDVNVTGEGDSESWLYLRNVLPNVTRASILERCEKIEGFLMLSLSEPHPLKELQRIGWIKFKPGVDLQEALNTLNEPPTEDFQAVTTAHRPTRARYTHEIANTEARIHADYELAVELAKLCDSNLAAPAEPDSEAIVYDGVSLLHARLKDVILESTDVAMEEEGEEDGAQSVIKRTNERRSLDLFIEYLRQVHLFCYYCGGDSDNAEEFTRKCSKHYRNPDSKVPANSKGAIWVKNLEQKINLKLKAPTDEEIVKLGGKSLEKGTLKFLQSKTQQDEPTKWRCKICTKPFRGEEFVHKHIRTKHPEEIKSIENNIQLFNNYILDPNHINPSAQQQQQLPPAGFGFGMPGPMFGGPPMPMNFMPGGHPMGMPFMNPGVSPMPGFPPGFMPPSFPTAGAMTGVSMDQIPRIGFDLPKRHNSKEDDKSKSSRPDLVPTRPPSMMLDPRSRMSDPRKVKSYVDLDAPAEGDIDAKYNLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWI7</accession>
    <name>A0A9P6SWI7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Alcohol dehydrogenase-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_004123</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002138">
        <property type="protein sequence ID" value="KAG0007875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWI7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42813:SF1">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G03930)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42813">
        <property type="entry name" value="ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Alcohol dehydrogenase-like C-terminal" evidence="4">
        <location>
            <begin position="83"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0007875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="281" mass="31295" checksum="277FB414C906BECD" modified="2023-09-13" version="1">MEKLYGQRTAGVLGYSHFVGGYAGVQAEFARILYGNTNLLKVPQDLPDEKALFLSDVVPTSFHAVKEAGVQPGDTVGVWGLGPIGLNVVQWLRNVFKASRIVAIDNVPERLKMAKEKWGAEVINFETDTDVSEKIKQCFPNGLDRSIDCAGFRYSKSLLHKAQSALGLETDTSEILNEMIRSTKKFGTIAIIADYAAYTNQFLIGGIMEKGLRLIGCGQAPIQKYWEVCLCHIEKGEFDPTAILTHRFPLEKTPDIYKRFDNKEDGIIKVFLETKFSKPPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXJ1</accession>
    <name>A0A9P6SXJ1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001976</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001472">
        <property type="protein sequence ID" value="KAG0009879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXJ1"/>
    <dbReference type="OrthoDB" id="2401745at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="16"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0009879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="525" mass="59367" checksum="ECDBF595F33314FD" modified="2023-09-13" version="1">MLHPLELPEIRHIIGAYLGSKDLINCACVSKEWNSTFSNLIWNHLTLKAAPPTLTVAQIQAHSNDIRYLTLETPLPDEYYFLENLHQLHSLHVEYKAYPRPGPILPHLADLIENHSPSLRDLEIHGGSNYLSPPAFKAVGMCQRLKSLSLNHVDVSQEEFAALLDACANIGQGMDDEGADATSNGRANGLTTLCLKSFNARNCESALFSMRDPLSYLKHLYIKTIFGLAPGAQLRLLLLCPNIRSLYWRRYKSGDNFLMDAWASYAESGIWPLLTSLDVSGEEFHDNGLFRFIKSRLLPLEKFLVRRTGFGPMAYNFIISTERHYNHIQELDIYECVNVTSHMIQKVMTTMHALRYFSAGHLRATDILDTFSLDPNGNDHGQEWICKDIRTLGLCIDMGQEFDSSSPEYAERQRHVYRRLSELKFLEVLDVGKGLGGCNSNGYDKSARGLDFRLSAGLGLLASLDRIRKLFFAPQPSMALKDVEWMISTWKSLKVVSPCLSNDQNISKTLKRRLAEHSISLQYPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZB4</accession>
    <name>A0A9P6SZB4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">MFS general substrate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_011393</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000910">
        <property type="protein sequence ID" value="KAG0012957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZB4"/>
    <dbReference type="OrthoDB" id="196103at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051617">
        <property type="entry name" value="UNC-93-like_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23294">
        <property type="entry name" value="ET TRANSLATION PRODUCT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23294:SF59">
        <property type="entry name" value="UNC93-LIKE PROTEIN C922.05C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="214"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="261"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="290"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="332"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="399"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="448"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="518"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="725"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="520"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="747"/>
            <end position="758"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0012957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="766" mass="84221" checksum="A4E0D53FD5D27FBA" modified="2023-09-13" version="1">MAISKAMRQIILIGIICSGTIGMFNAMSSIGNAGRHSPTAQNLAITSSSIAYIIGFLLAGATHNLIGPRLCVLLGGISFILYAGSMMLASDNDHSIYPPLAGILLGIGAGLIWVTQGAMMMSYPTENNKGKYISCFWALYNIGAVLGSILPLVMNLEPDMDPDDVSSLTYIVYMAVMGAATFLALFLSRPSSILRDDGEPVKVEKFAGLKAEGLAILSVFCDWRMLLLIPAFFFSNFSYTYQFNDFNGFTFNIRTRSLNSIIFWVAQIIGALLIGYLLDRMPVRRPKRAMIGLLIVALLFMATWIAALIVQLKHRWERRVLHKNELIDYGHGSYVGLGFIYGMFGFCDAAFAVFCYWLMGALSNKYDELSRYAGFFKSIQSLGSAVAAPLDLAQTPLQAYLITNWIICALSIAAMFLVCRTVTDTTLEYEGDDNEEELEYYDEEIDDSSYDTSVDEHDENGQNHVSGKHTNSPERDKSTVCVTDEVEEKLYGSQLGAQSSSCWRSSRTTSGIQEDYIEEQGGSQSQSRSSHSFLEPGERISYNSSPASAASNMAYPRRAYQDQHQYYAQQPSDRSIYRPGGISTMTEVPHDLSAGLGPAYWIEHPLSTIGTQQAFYPKSQSSIPEPSTSTPLSDTNVSFQPGSSAGTSHFISAPTFMISDENSTPMPLYASQPELFYHYSQWLAEGQATTAEAEIQEEVAEGSSNSPVAAEFLQPHNQFHPIAHTASSAGSTRYDDEQDMDMDSTDTHSISSMSSGHDSIPEMTEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T033</accession>
    <name>A0A9P6T033_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein SDA1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">SDAD1</name>
        <name evidence="12" type="ORF">BGZ80_009965</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required for 60S pre-ribosomal subunits export to the cytoplasm.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
            <location evidence="6">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the SDA1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000647">
        <property type="protein sequence ID" value="KAG0015225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T033"/>
    <dbReference type="OrthoDB" id="2196187at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000055">
        <property type="term" value="P:ribosomal large subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027312">
        <property type="entry name" value="Sda1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048292">
        <property type="entry name" value="SDA1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007949">
        <property type="entry name" value="SDA1_MD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012977">
        <property type="entry name" value="SDA1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12730">
        <property type="entry name" value="HSDA/SDA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12730:SF0">
        <property type="entry name" value="PROTEIN SDA1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21638">
        <property type="entry name" value="SDA1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05285">
        <property type="entry name" value="SDA1_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08158">
        <property type="entry name" value="SDA1_HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4 6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="2 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SDA1 N-terminal" evidence="10">
        <location>
            <begin position="63"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="domain" description="SDA1 middle" evidence="9">
        <location>
            <begin position="524"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="domain" description="SDA1 C-terminal" evidence="11">
        <location>
            <begin position="705"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="496"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="633"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="260"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="498"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="541"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="554"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="574"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="651"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="675"/>
            <end position="702"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF05285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF21638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0015225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="753" mass="85450" checksum="D6F3CDF82E4B7175" modified="2023-09-13" version="1">MGKRNRAALLPTNIPQLQNLIKRDPLSYKEEFLQQLRHFESSRAIFELKPEEHSTDFQDLINFIAQVSPCYPEETKEFPDQIITLLSKHYQILDAELRRTMVQALVLLRNREMISSTSLLSLFFTLFRCRDKILRDILYNHIVNDIKVSNQKAKNNKLNKTLQGFMYTMLTSAEGAAGTGSENAIAAKRSLDVCIELYRKNIWNDAKTVNVIAHACFSPVTKIMVTALQFFLGNNEDGDESEDEDELPDIKAMQHKQNVSKKTKSKAKQMEKMVATLKKKSKAKKRAETFNFSALHLLNDPQGFTEKLYTHLSSSRERHEVQLMLMNLISRISGIHKLTVLAFYPYLQKRLQPTQKDVTQIIAITAQSSHDLVPPDVIEPLIQTLANNFVTEHCAAEVMAAGLNGIREIVSRCPLAMDATLLQDLTEYKNHRDKGVMMASRSLIGLFREINPELLKKKDRGRSAAMNMRNIKPSMYGESNNDADLEGLQLLAENAGEGGEEGEDNWDGWEEASEDEDEEDGEGWINVSDDEADLNIKLSDDENSGSEDEDGNKKPKAKRLTVNKERRLKKKGMLPKDDDSETVMKEEDEETKAKRLQMEAERKEKLAAAQLLATTKILTPADFAKIESLKLAKQADQKLNPTRAGSGKRPAPTDENRAEGEVSIGSIIGPRKKAKQDYAERMESIKNGREGREKFGSRKGSTERGSTTNKEKAKGKNFMMIAHKREVREKKKMSLREKQIQLHAHIKKQKMMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0A3</accession>
    <name>A0A9P6T0A3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_009877</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000631">
        <property type="protein sequence ID" value="KAG0015408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0A3"/>
    <dbReference type="OrthoDB" id="2358488at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38926">
        <property type="entry name" value="F-BOX DOMAIN CONTAINING PROTEIN, EXPRESSED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38926:SF72">
        <property type="entry name" value="IM:7136021-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0015408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="570" mass="65466" checksum="F15A4A6BDCA58D99" modified="2023-09-13" version="1">MSSASNVLSARDRVLSIPELVQGIVQFLRPIHLSQLRLTSKRFHNAFTPYVTLAVSQDYYKDCESALKALTDVGSMVKSLRVDALGNESNLEIMLERSRAIERVDFRAWTSYDRLFYKILECQPTLKDLTLTLCGDSIKANIADLLSAIARQAPPLETFSLTVQVIGNIKTPWSNISSILDACSTIRNLSFRGFNISRQEDEPQQPQIQSLALSDAHFGHSDILFFLHTMPGLRSLSLHLYKEPAQVFHTLMGDLTYPSKNILTQLTKLKVVATRKSHITGLVRFIQDCCPRINDLELGGECQYVSRGDVLGLLDHFNLNDITLKRLAIDYIPGSYVEDWIRRMLERCCPELEELELGGGVQFFIETQDYIYKWRKSGEFSMKQQEQKFWFPFSSTLTKLHLNNLITSSGPHWYFLNQMLRSMPLLEDLAVMGLLSEYSLFDGLGNDNALPRPKHHPLEYCIFKYLDSNNVIPLPEKQREEEETVPYESQDWTKERPFLRFLKIGLQPSVGFEAEVWNRELVNRFRFLEHLSIKTDLSHPEMELLGEWEETLRPGLGFTLLRLGMSSPWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0R8</accession>
    <name>A0A9P6T0R8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_009413</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000561">
        <property type="protein sequence ID" value="KAG0016141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0R8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0016141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="146" mass="16175" checksum="9AB05D243C18F3C3" modified="2023-09-13" version="1">MHSLSDFGSQTPDNSPLEIEQSSPSPSSTQQTVTDQSSATEQESTKNAALCDTEEDVLQFAYRATATPAMLSRPLRFDTSNSGCGRRKRSGEEELEVEDGDKQTEFTDEIRGRNKSNDLDHRDCLAPRMGIAAVAVNEEDVYTIYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1F2</accession>
    <name>A0A9P6T1F2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">VTT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_007882</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000412">
        <property type="protein sequence ID" value="KAG0017823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1F2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015414">
        <property type="entry name" value="TMEM64"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032816">
        <property type="entry name" value="VTT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12677">
        <property type="entry name" value="GOLGI APPARATUS MEMBRANE PROTEIN TVP38-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12677:SF59">
        <property type="entry name" value="GOLGI APPARATUS MEMBRANE PROTEIN TVP38-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09335">
        <property type="entry name" value="VTT_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="178"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="211"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="289"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="342"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="438"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="domain" description="VTT" evidence="8">
        <location>
            <begin position="193"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="378"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="388"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF09335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0017823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="467" mass="51468" checksum="219FBFBAC14C90E4" modified="2023-09-13" version="1">MANEQGITRHQSGGAFDQETQETSVVRTYYEDDVDDDEIRGGLWNRGGSEQARLINTGGAAIAAEYVDSQRLTQYQNGSYHSLHTLLNKPLLEEGGLLGGQDNDSDDDEQKGTLTTTWMEWAVKNGLHPSTWTRQTYLKGSLLAILLTLIILAFTVLRVQDHVKEILLYIDEHRSMGAVLFVTFYTIACWLFLPGSLFTIGAGFLFKPMPFALAIVILGDFLGALGTFLFGRYLFHDWVKGLMSKHPKFNALDEVIKDDGKCFLIKRTHFDIGWKIVVMLRLTPIPFNLITYFFSITSISLYTLLGGTVAGVFPGSCLGIWIGSMLQGLSGIDNPDLEPKNVVILIMNGAFIVCSILTLSIFGKRSLRKALSKLDQHQGAMSSHAEDHEEDEGEDDGDNRTEGDSETTAVDMTGANLTSSGAAASDAASTGFTRGEKWMFFGIVVVAIVNVSVSIPLYFHYANKKDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1W5</accession>
    <name>A0A9P6T1W5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Sn-diacylglycerol cholinephosphotransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_006218</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000306">
        <property type="protein sequence ID" value="KAG0019169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1W5"/>
    <dbReference type="OrthoDB" id="196717at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016780">
        <property type="term" value="F:phosphotransferase activity, for other substituted phosphate groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048254">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014472">
        <property type="entry name" value="CHOPT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10414:SF77">
        <property type="entry name" value="CDP-ALCOHOL PHOSPHATIDYLTRANSFERASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10414">
        <property type="entry name" value="ETHANOLAMINEPHOSPHOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015665">
        <property type="entry name" value="CHOPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="151"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="227"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="264"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="296"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="325"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="360"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0019169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="420" mass="47468" checksum="93E3AD5EFF2D893C" modified="2023-09-13" version="1">MFGIGNRIQESDYVSDAGLANLRLYKYGCVDKSPVTKYFLSHYWNWAVTLFPMWMAPNLITLIGFGFVVSNMLLVIYYIPDLFTPGPTWIYFSCSIGLWLYSTFDNVDGKQARRTGTSSPLGELFDHGCDALNCCIGAVNQAACMSMGHSWYSAFLLLLTTLPFFLSTWEEYHTGVLYLGYINGPTEGLIIACVVMLISGFKGPLFWRNEIVDVFGTDFGVFPKGWILLDLMVLGMTLLLVFGHIPPCMLSVYKACKEQKKSVLVAYSELLPISLFLVSAYAWLSSPYSYIFRNQHFILFSVTVGIVFGRMATKIILAHVTKMPFPYFTVQLIPLVVAAFITNAPVMLGWDPIFTPETEYYYLWAYFIFVAVAYAQWALLVIDRFCTYLGIKCLTIPRPKAQQSEEEEGLIGAAPRNYQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T202</accession>
    <name>A0A9P6T202_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">MHD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_007574</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <location evidence="2">Coated pit</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the adaptor complexes medium subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000390">
        <property type="protein sequence ID" value="KAG0018090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T202"/>
    <dbReference type="OrthoDB" id="10259133at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030131">
        <property type="term" value="C:clathrin adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005905">
        <property type="term" value="C:clathrin-coated pit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09251">
        <property type="entry name" value="AP-2_Mu2_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14836">
        <property type="entry name" value="AP2_Mu_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.60:FF:000002">
        <property type="entry name" value="AP-2 complex subunit mu, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1170">
        <property type="entry name" value="Mu homology domain, subdomain B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050431">
        <property type="entry name" value="Adaptor_comp_med_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036168">
        <property type="entry name" value="AP2_Mu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043532">
        <property type="entry name" value="AP2_Mu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022775">
        <property type="entry name" value="AP_mu_sigma_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001392">
        <property type="entry name" value="Clathrin_mu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018240">
        <property type="entry name" value="Clathrin_mu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028565">
        <property type="entry name" value="MHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043512">
        <property type="entry name" value="Mu2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10529">
        <property type="entry name" value="AP COMPLEX SUBUNIT MU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00928">
        <property type="entry name" value="Adap_comp_sub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01217">
        <property type="entry name" value="Clat_adaptor_s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005992">
        <property type="entry name" value="Clathrin_mu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00314">
        <property type="entry name" value="CLATHRINADPT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49447">
        <property type="entry name" value="Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00990">
        <property type="entry name" value="CLAT_ADAPTOR_M_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00991">
        <property type="entry name" value="CLAT_ADAPTOR_M_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51072">
        <property type="entry name" value="MHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0168">Coated pit</keyword>
    <keyword evidence="5" id="KW-0254">Endocytosis</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="domain" description="MHD" evidence="10">
        <location>
            <begin position="169"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR005992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0018090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="426" mass="48637" checksum="DF6498CDC663EAA2" modified="2023-09-13" version="1">MISALFIYNQKGEVLISRLYRQDLKRSIADIFRIQVISNTDIRSPIITLGSTSFFHVRHENLYIVAVTKWNANAALIFEFCYRVINIGRSYFGKFDEEAVKANFVLIYELLDEVLDFGYPQNSETETLKMYITTESVKSERAIMEDSAKITIQATGATSWRRSDVRYRKNEAFVDVIESVNLLLSAQGNVLRGDVTGQIMMRAYLSGTPECKFGLNDKVLLEKDPTNRKKSSEAVEIDDCQFHQCVKLGKFDSDRTISFIPPDGEFELMRYRTSDNINLPFKVHPVVTEIGKSKIEYRILVKANFSSKLYANNVVLNIPTPLNTTGVICSASNGKAKYVPADNSIVWKISRFQGQSEFMLTGEASLTAMTHKKAWSRPPISMDFHVLMFTSSGLLVRFLKVFEKSNYNSVKWVRYMTKAGNYQIRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T227</accession>
    <name>A0A9P6T227_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HTH APSES-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_006532</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000323">
        <property type="protein sequence ID" value="KAG0018932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T227"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030907">
        <property type="term" value="C:MBF transcription complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033309">
        <property type="term" value="C:SBF transcription complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.260.10">
        <property type="entry name" value="Transcription regulator HTH, APSES-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036887">
        <property type="entry name" value="HTH_APSES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051642">
        <property type="entry name" value="SWI6-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003163">
        <property type="entry name" value="Tscrpt_reg_HTH_APSES-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43828">
        <property type="entry name" value="ASPARAGINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43828:SF5">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR XBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54616">
        <property type="entry name" value="DNA-binding domain of Mlu1-box binding protein MBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51299">
        <property type="entry name" value="HTH_APSES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH APSES-type" evidence="2">
        <location>
            <begin position="123"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="490"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="622"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="82"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="269"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="284"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="300"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="321"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="397"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="503"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0018932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="642" mass="71720" checksum="D953BB8FF6FA0522" modified="2023-09-13" version="1">MLGHQQLLQQQHQHIHAHQHQQQQLGYQGSKSSGGHTKQLSSHLPVSNFSTSSTASASVINTKPSSANASLPPAYPYPSRPTTPVSAPSLPSVSSLSATLTSASGDTSTRAGENFVPNIKKAKYSTSLDPRGFIPVFEYEIYGHPIMWDQENMYVHFTGIWKALGKTKADIVKIIDANPILESIIRKVRGGFLKIQGTWMPHQEAYDLAKKTCYKLRYELAPVFGPGFVNDCIPPGAQGFGSILLTVVRRRVSECVMRPNMRPQQLRLHQTHIHPSLKRRHSSNDVNRLSRFSQPNGPISSQLSSSSFLLNRSKEYQQDGGDGDQDDDLDLDMGDEDLGPNQNRNTVVRTRQHRFRRTGRSSWGGSNDDGDEDDQDRLLDGSTEDEEERQSLSGSYDGDDIDIDGESCTSEQDDPMYDLARLNLSRRNSSPMPLSAVYALSGSGFSTKSSVARTKRGRPPTRSPMLVASRIAANYVAYNNYVSSNTQVAQGLGRSNGHSTRAQKQQQQLRQQLKLQDQMQQHQQHQQQQQQQQQQQQQQQQQQQYHPLQMPISQRVSSAPAMMDLTHQELVEFFKAGQALQRMSQDDGVRPWKQDGDRMILPKKVVLGEQVFQCVGGEYKCVPEPNNSSSIKPPGEGDGWSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2J9</accession>
    <name>A0A9P6T2J9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004107</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000213">
        <property type="protein sequence ID" value="KAG0020504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2J9"/>
    <dbReference type="OrthoDB" id="2372673at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="197"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="256"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0020504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="291" mass="33178" checksum="58183F7551606267" modified="2023-09-13" version="1">MIEVDVFWSFSFGAIFAATSAGSLKDEAVFWLTPSFVYTLLFLSLIFAPSGLYLLWDNPGWESMFLLGDKNDIHALLPTIFAFTNVLLGIIGYYVTYCKIRKYRTSAKLPMSYHKYWIHAYTCFCAILGMGYSRFMYPSDYVAWRADVQYPLTAFFTSRIFFTLLAMGVVLIPAAYIPCFIWMKNQTLTAPGDKSRFFLTCIHFILQGTCLVSALFGAYIVRNHENDPSNSIVANLWQLFDNGNILDRESKWSPLLGFWVAETAVMFLVFLPIFFVPSVKTAAVQKTTKTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2Z2</accession>
    <name>A0A9P6T2Z2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein SSH4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_004814</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000241">
        <property type="protein sequence ID" value="KAG0020088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2Z2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12909">
        <property type="entry name" value="SPRY_RanBP9_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001870">
        <property type="entry name" value="B30.2/SPRY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043136">
        <property type="entry name" value="B30.2/SPRY_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013144">
        <property type="entry name" value="CRA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024964">
        <property type="entry name" value="CTLH/CRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006595">
        <property type="entry name" value="CTLH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003877">
        <property type="entry name" value="SPRY_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035782">
        <property type="entry name" value="SPRY_RanBP9/10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050618">
        <property type="entry name" value="Ubq-SigPath_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12864">
        <property type="entry name" value="RAN BINDING PROTEIN 9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10607">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00622">
        <property type="entry name" value="SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00757">
        <property type="entry name" value="CRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00668">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00449">
        <property type="entry name" value="SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50188">
        <property type="entry name" value="B302_SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50897">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="B30.2/SPRY" evidence="2">
        <location>
            <begin position="248"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="domain" description="CTLH" evidence="3">
        <location>
            <begin position="534"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="236"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="599"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="40"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="130"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="277"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="599"/>
            <end position="610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0020088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="750" mass="81915" checksum="51F93527F4E56188" modified="2023-09-13" version="1">MSLPDHHSSATPTNVTNEDHTVLSGNESTNAQSQLSRSQTPTPLSPTLILPPATTPTTAAATETAAPSSTTTLRTSIGADSEQSSLSPPVTSMDTEVLSDTEVPSVSVRQDLLSSIRANAGNPPSNVLISTATPTWPSSSSRTHTSLSLATTGRRYPQPPLRSSQLGASQQHSPRAPLPLPEREDSSRPRAITFGTLKKASMSHRTPSFIPTEKKSKMVALPSYLQYTTFKQHFQPEGGIGEHGLGSSLDREHSKRRRLLTDTSRRRHTHIHHDSDSSVSSSGDSSSGSSSSSGSDSSYENDSTFTPKSERPGKHDTDASSIRANRHIPPQCGVYYYEVLIKSKGQQGDWRWEPQSWGYHGDDGNSFEGCGNGRPFGPVFTTGDTIGCGVNFRDMSLFFTKNGVHLGVAFRNLKGTLYPTVGMRTAGEIIEANFGQREFVFDIDNYVKNEKVEAWQLLERSIQAAIVEKKQLGNISQNLSQLVLSYMIHHGYSESAKQLAGDLALQSSQSQGPTGTISSQAQIDSTNCLPMIADSEKRKVIRNKILAGEIDKAMELLEKHYPGITADYGDMLLQLRCRKFVEMVSLASTPLRKLDQGECKKGDTKGKSTELMDVDQDPSIKPSSSMEADQEDLEGLGMLKDAIKYGQFLQEHYKDNRRRSVQDMLVDAFSVLAYTDVEKQPGSESSHQAKSITREKVANTVNRAILSSQNQPTTAPIETLYRQTTAIMSELTSLGVGAAAFYDVDRDCLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3F0</accession>
    <name>A0A9P6T3F0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Myb-like, SWIRM and MPN domain-containing protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_001380</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000131">
        <property type="protein sequence ID" value="KAG0021948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="118550at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd08067">
        <property type="entry name" value="MPN_2A_DUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000020">
        <property type="entry name" value="SWI/SNF complex subunit SMARCC2 isoform c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050242">
        <property type="entry name" value="JAMM_MPN+_peptidase_M67A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007526">
        <property type="entry name" value="SWIRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10410">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04433">
        <property type="entry name" value="SWIRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102712">
        <property type="entry name" value="JAB1/MPN domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50934">
        <property type="entry name" value="SWIRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="SANT" evidence="9">
        <location>
            <begin position="171"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="10">
        <location>
            <begin position="175"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="6">
        <location>
            <begin position="175"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="SWIRM" evidence="8">
        <location>
            <begin position="721"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="domain" description="MPN" evidence="7">
        <location>
            <begin position="1022"/>
            <end position="1159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="133"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="222"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="286"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="385"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="553"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="646"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="815"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1266"/>
            <end position="1332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="147"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="257"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="295"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="328"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="399"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="453"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="843"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1266"/>
            <end position="1275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1285"/>
            <end position="1306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1307"/>
            <end position="1328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0021948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1357" mass="150016" checksum="84A0FA845840C582" modified="2023-09-13" version="1">MADEEDDIDIDIDIDGNEPEEQVNNKPVDLKDSKILQLSDHVHMDSASDPGNKSHGVGHGEIVKNLRAASVDPDTSLADEFQIPDWVTQDYHAQADFDSGDMDPKSRAMIESMLAEEQFYSGRSSVMSFDIHGRRSPSAVVPKKSRTGSQLRGASSNSRLNAKLSSADLPSHNTRWTAKEDERLRHGISIHGYGNWKLIASIVGTRNPLQVKNHARHLAMSEKMPYDVSTNTSDGEGLDRRSSAANSAEEEDASNIRNRKRRPRSKHVKRIDASAITDINGYASYSRRGRRARSITSESGNEEFTGSEFGATSGYDTDNDDDRSASKSPSLSARGGSRSGSTGLTTPSPGLRPLYSALPLPYTISTPKSLTFSMDEDEDIDVDIESTDEEPSSRPSLAPPFSIKSKSRSISPFSNSSTRSRLSSEFDSDSDRNLGGEDGEDLLRSGNIRKRSSVSSPAPSDTIGSSSEFYTTPNFNTSSSSINSTGAIGSFKPLLKDTHNQQYHHQQQPQHYQHQQHKSGPLGLISMEKMVNSPKEKRTVSFGAVHVAELQPDLNSYDEDDVNSSEDGGVDTTGLSAMDTIAQPSPLSNPPYRHHVTTKNIQSEGTLSLSLHAIANDGTCADNPALQDPTQNSTSNGVYSKKALLNQTSDPDDEDEGLLGTGLKRNSNSAVAPSFPRKAQRAGGFKQKSSFSISGSVGHSVSFQASPTIISTGQLPTIPTLTPPVIPRVLDKSIITEEEKLVHSEFFCNKASKTPERYQRIRNTIIQAWERSPSTYLTKTSVRSGLKDCGDVNAIGRVHSWLESIGVINVGMTASSPGASLARPRNGGNNSARRRGHSEERGWSSSSSSSAPRRTHSDANMLIDDTDSLWVAPSMRRRRVRNEKGEWVDEKELEGRVIEHNVHINSNSKLERQTSRRNNPSDDLLNLDDDAFFERYGITKDEMEEELDQERLAAQNAKYFAATELMSVNTRVPKNRRAQHLLRKAEGFDKYEADEGGPSSYDPFRLVSLSKFSSQNPAPFRVKVSSDAMLIMDFHSHMAETEVIGLLGGLYDEDERILFILGVFPCRSISTGLQCEMDPESDVEARYFFSSKGFVVVGWYHSHPTFEPNPSIRDIENQCEHQNMFRRHGTGVEPFVGVIVSPFDPRNLSFLSKFQFLAVSEQFDEQLSCRIPFRFDREITRMNELSVSVFQQISELVRYYRTYEHKVDLSQPLRKGETSTRLEKLLRSLNHHIFVDESTGQAFLSKVKELVVRGFHLTIEHDPSTTFASHTQSAQPPIAPSTLPSQKHQSSSGLSSHGTLLSPLPSDVKDGSSSKMKINDPTEQETCKETVSTTTISDIEVERAVLTPPLFDKDPGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3P8</accession>
    <name>A0A9P6T3P8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">PROP1-like PPR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_000431</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Regulates mitochondrial small subunit maturation by controlling 15S rRNA 5'-end processing. Localizes to the 5' precursor of the 15S rRNA in a position that is subsequently occupied by mS47 in the mature yeast mtSSU. Uses structure and sequence-specific RNA recognition, binding to a single-stranded region of the precursor and specifically recognizing bases -6 to -1. The exchange of Ccm1 for mS47 is coupled to the irreversible removal of precursor rRNA that is accompanied by conformational changes of the mitoribosomal proteins uS5m and mS26. These conformational changes signal completion of 5'-end rRNA processing through protection of the mature 5'-end of the 15S rRNA and stabilization of mS47. The removal of the 5' precursor together with the dissociation of Ccm1 may be catalyzed by the 5'-3' exoribonuclease Pet127. Involved in the specific removal of group I introns in mitochondrial encoded transcripts.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Binds to mitochondrial small subunit 15S rRNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CCM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000109">
        <property type="protein sequence ID" value="KAG0022354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3P8"/>
    <dbReference type="OrthoDB" id="5588846at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033443">
        <property type="entry name" value="PROP1-like_PPR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447">
        <property type="entry name" value="OS03G0856100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447:SF17">
        <property type="entry name" value="OS12G0638900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13041">
        <property type="entry name" value="PPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13812">
        <property type="entry name" value="PPR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17177">
        <property type="entry name" value="PPR_long"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PROP1-like PPR" evidence="8">
        <location>
            <begin position="210"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="5">
        <location>
            <begin position="238"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="5">
        <location>
            <begin position="307"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="5">
        <location>
            <begin position="342"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="818"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="46"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="818"/>
            <end position="828"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00044493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0022354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="897" mass="102176" checksum="19D42E896C176C19" modified="2023-09-13" version="1">MAHLAAAINRRAFLPKIALGSPRLARHLKPGTWFQSSIRAYSHKTKTKIQIETSELEQEIKQLERMIAEQERKLAGKRALEESIRESKQRSEAAKDVYKSLTSPIATSSPSKQIGANPNSQSYLPETFLQDLKVTFLDTRESKEETIKQLQSELPSGDVLRAASISQDDQETNGEHLEPAPSALTATEKDANVLALERIKKLGVDEWNKLIYVNALDSNFKNAEQVMQLMEEVGVDPNMQSFDYLMEAYCNSNNLQKAESTIELMQTNGLTPSLSAYNSLMKIHVHRRSITSAFHVFEALKEHHNPDVDTFTNLIKGCLRAEEYDLGWKIFDQMQHSGAPPVESTYSTMIQACAKTDQVERALDIFRTYPTRGLQPTDVTFNGLIHACAMRPEYFTTAFALLNEMQNVYGFVPDIATYNTLLFACSKRKELLTARRVFQKVVQLDNEGALKLDGVTVTNFLWCVTEWKDTDVHIRNLKYRLRDPALAQIESAPTVQSEPGTGDDLELTIRPSYFTFPTKPPKDEREALAEGELVFNWFLSRSAEQFPFVEDKDETSIRAAEPEPHEGQEQSDAIVTKTTTTDLAIPRTSRHSPIRTRLLNAYLAMYVRHQDMEKATEIYRRYFDHFQRKRDSWTYSTMLEGCYNWKDVDLGAEVFRDWRSWRLSTGKLTEKRTRQSDYQCYRRMINLLARTNHLDESIALLEELSIAATPVNTRLRSEIASAEASKSLQSSSTSDSTLASASKSELASASTSTSTALAASTGTDMTQLLLQGIEENVLPIYPKLKDFPVVYTKTWELEDEGSRRLLLRLCHGKVDSLHASSASRNNGETSEEQDGDRSIMQEYQDKRRSRYEKALRNTSIKWKGEHPQEKGFYVGSRRIRELERDLSKRGQDHRRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3R6</accession>
    <name>A0A9P6T3R6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Splicing factor Cactin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_011347</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CACTIN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000090">
        <property type="protein sequence ID" value="KAG0022741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3R6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019134">
        <property type="entry name" value="Cactin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018816">
        <property type="entry name" value="Cactin_central"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21737">
        <property type="entry name" value="POLYGLUTAMINE BINDING PROTEIN 1/MARVEL MEMBRANE-ASSOCIATING DOMAIN CONTAINING 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21737:SF4">
        <property type="entry name" value="SPLICING FACTOR CACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10312">
        <property type="entry name" value="Cactin_mid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09732">
        <property type="entry name" value="CactinC_cactus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01050">
        <property type="entry name" value="CactinC_cactus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Splicing factor cactin central" evidence="6">
        <location>
            <begin position="221"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="domain" description="Splicing factor Cactin C-terminal" evidence="5">
        <location>
            <begin position="582"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="99"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="181"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="7"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="99"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00034534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF09732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF10312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0022741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="706" mass="82463" checksum="65C7A3CE99D077CE" modified="2023-09-13" version="1">MKAETGTETEAEIEIETEMEMETETETGTETETETETETETEMVIKTGIEIGIEIETQSNIVADLAIEAETEIRTETETEALGVTETRIARMVEKTVVDLKSKRDEDESSRKPRETSEERAIRKAQKKKEKEEQKKALEIAMTNYSNADNPFNDANLAQKFTWAKKREVEKKKGISSAESARRDAIRREEARVELEKLKKKRAEREREREEREEELVRIQRASEQAQLGDWQAQEEEFHLKQAKRRAEIRIKSNRAKPIDILAMNIKLITQDEDDMEEDEEDIGLEIDVEEPYTIFDNLSLEEVEELSHDIKFYLSLDKNEQSMDFWRSMLIVCEDKLADLNPYRAEQSVVAPHIAQDIASRLAGKSYEELTLLQGQIQSKLSSGGAIDVDYWEALLKTLIVWKAKAKLNAIHQVILQKRLDQLKTRQLYEAEKEKAELAAVLAMQSQEVEGDTSAIGRMEDQDMDLAQDDYDQDMGSSSAIPYDRAMSPEPFDTLTREDQNIAVVDQWEDWAEILEKRRQVLNKQFNPKRRNPDQDAGEQHPDDDFVSKILFDKEAAKQLAGNEEVFNIEASLQRQQTYMWQDKYRPRKPRFFNRVHTGYEWNKYNQTHYDHDNPPPKVVQGYKFNLFYPDLIDKSQAPTYEIIKEPETTDTVLIKFKAGPPYEDIAFRIVNREWEHSHKRGYKSVFDRGVLQLHFNFKRQFYRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MCR7</accession>
    <name>A0A9P6MCR7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_008526</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004647">
        <property type="protein sequence ID" value="KAF9992497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MCR7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9992497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="136" mass="15223" checksum="0412108AB5455594" modified="2023-09-13" version="1" fragment="single">MAVLCPPDLSDSARKVLEDTAKTCFLNGCPADLRQMLQDLDIAVGNKKTVHERCAAAEGFDVIYHFTTESPAASPSGMQLFITAHAAAATQRDPMAMEIDALRLQINALQQQQYRRNNFRHNGPRPLYRLSHNERQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MCW8</accession>
    <name>A0A9P6MCW8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PDK1-type PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_008324</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004479">
        <property type="protein sequence ID" value="KAF9992972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MCW8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033931">
        <property type="entry name" value="PDK1-typ_PH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14593">
        <property type="entry name" value="PH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDK1-type PH" evidence="2">
        <location>
            <begin position="240"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="56"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="207"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9992972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="313" mass="34483" checksum="A56FC93325E7984A" modified="2023-09-13" version="1" fragment="single">LFYSNTNESYSWWYQQQRVVQWEQLEQQQQQYSVHQQLGGLSLDSAKQHHLYQHPSLSQESQNHQQQQLNAIHQPLQSPAARRSTGGKDMPPATTSSGFLLSRNGSSRHQQTRSEHIPSSDQTEATRSARGSIDHTPHQHQHSHMAHHRQQSNGYNKIDVEKPTLLVQGASSPSTDSSLISSELNTTALAGNSPVPGSKSNVTLSASSNGSGSINGSSITGTNKTSSVAAPPPTKIKASKKQAKLRGEILFTASVVSEVKGKKCFFIHTTKKSYYFEESKEGDAKLWIKVLERCMEEWFGEKSGAIEATSATE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MDS7</accession>
    <name>A0A9P6MDS7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_008008</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004219">
        <property type="protein sequence ID" value="KAF9993846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MDS7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9993846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="160" mass="17632" checksum="73AB515E9C1F6C11" modified="2023-09-13" version="1">MIRNFFPSRTSDLSPEEALELVNKRLELARKEDDSAKKLNLINSAKSRLKDAENIFTSTEVKDPALSEGIAHAYHEHGRLLDALGHQGKAKKSHSKAEKWGYVGAIDRDIGSFHPLGKSDAVRRSLLPTAALSAAPIVTVAMYQDSSKADVTQRNNQDHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MEL3</accession>
    <name>A0A9P6MEL3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_007540</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003882">
        <property type="protein sequence ID" value="KAF9995349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MEL3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052542">
        <property type="entry name" value="Cholesterol_Oxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47470">
        <property type="entry name" value="CHOLESTEROL OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47470:SF1">
        <property type="entry name" value="FAD-DEPENDENT OXIDOREDUCTASE 2 FAD BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="5">
        <location>
            <begin position="78"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9995349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="429" mass="47676" checksum="D16C5929B4DC7A46" modified="2023-09-13" version="1" fragment="single">ADTTSVADNLKAITEFSVSTINAKVKSYLPFLNELQYAEDSQKRKGFPRQRPTPQVFEVVSSDGFNTQLTRYKGTKGPVLLLHGVAVSSKIFSTDLIPHNLCDYLLANDYDVWLSDWRASILLETSRRQSPVYGGAFDHAAAIKIILKETGVKNVQVVAHCVGSLTLWAGMLNGDIEGVGSVVSSQIASRPMVSIANKIKQNLQLAPFFEKVLRQDHFDIVAHSPSPSTSEHGSGGDKTAHKVSLLDRAVDNALRFMPMPSQEYCNNAICHRASFCFGLIWEHDKLSKNFHDNLNEIMGSINMETLQGLVNVWSKKQTLTNLEGKDVVTPENLKKAFENVPVLLIHGAKNQAFTPESTIRTLNELRSNILPWTNMASDSKSIYRRKEIPGYGHLDCITGDKAYKDVYPFILEHLETYSKTTGYGAAIEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MEY2</accession>
    <name>A0A9P6MEY2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Arm-like repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007227</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003665">
        <property type="protein sequence ID" value="KAF9996507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MEY2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056251">
        <property type="entry name" value="Arm_rpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23948">
        <property type="entry name" value="ARM_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arm-like repeat" evidence="1">
        <location>
            <begin position="1"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF23948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9996507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="545" mass="61449" checksum="A164E885CA801C61" modified="2023-09-13" version="1" fragment="single">MATDIIRAFVRDELKMSDVVAETLSLAAVLNRDESRKLLEAFVDAIDQSLLLKVNLLDGLSHLMKNIPLGDLDSDDLVKILELLSMRLKGTHQQSTHHIYQLSLTVPRVLDSMVDSQVEGIEREPLHEPLSQYLMDLQQSSDPCLVYQAAYAYQALQYIPDDETILQTMLRRTGKVVKGISGVVAAVKALDLNGFIDGLQHIQVGLSGASEATSMVSGACLNTKTLIESGHGFLQSLQESFSFTRKSAWYPALRGLDSLLQEGKLTEFEKLAREAPCRKDPAFQWGVCQRLGEIAMNTLWDTNTRQCAISFLGEMYSNDTTWGQHTSVKQLVLQVLSKLTESSEGTVANHAESQLQDLEMDGDSKKRDLYHACMQENQSQYILTATSPSPRECRLLDRVQNKQDVESTLHQLKRERLKEQGQDVYISPRAKVNANTTEDFDLTSKVQEFLNSNKKVFLLLGDSGAGKSTFNRALEIDLWHKYNKVGGKIPLFIHLPAIKDLERDLIEERLRQANFTENQIRELKLHHEVILICDGYDETQQTRNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MF23</accession>
    <name>A0A9P6MF23_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Armadillo repeat-containing protein 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ARMC8</name>
        <name evidence="7" type="ORF">BGZ80_007522</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003871">
        <property type="protein sequence ID" value="KAF9995405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MF23"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034657">
        <property type="term" value="C:GID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038739">
        <property type="entry name" value="ARMC8/Vid28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15651">
        <property type="entry name" value="ARMADILLO REPEAT-CONTAINING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15651:SF7">
        <property type="entry name" value="ARMADILLO REPEAT-CONTAINING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="220"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9995405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="285" mass="31893" checksum="229902BFD8D84DA7" modified="2023-09-13" version="1">MERGIVAKFVQMIGYGDNIVRLNVVWAIKNLVFEADSDVKEAVMRQFGYHNLARLLNDRELSIQEQALNLVRNLACKKEQDIDKVFNGLGHGQLLSIIEDKLTWDDPSLLEHALYVLVNIATGSEHHKQSIMKRPLILKSVIGLMSHESAAIRVATVWVIINLTWPDEKMASGAHDRTMQLRNMGVEDRLLSLNSDLDLDVRDRVKTALHHFFSDQQQYGLNGSGMSDQSNSTGNSRLNHNSRNTSHNVIGQSQDPHTTNESFVNAGMDTSSTLAGSGTPSHERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MFH3</accession>
    <name>A0A9P6MFH3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007256</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003688">
        <property type="protein sequence ID" value="KAF9996376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MFH3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="199"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="262"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="49"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="199"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="287"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="333"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9996376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="387" mass="41504" checksum="9F4C3DA53509082C" modified="2023-09-13" version="1" fragment="single">PESPVNRKRTDDDSASGQGHRHQDGSTSSNTLHPTKKSKTSPPLAPTINNHASNNNNNNGNNLHLNSGNNNGHTLSDYRTSPDDALSPQTSPILEPLMPVHVVSMTEKRYSPVTDVPVQSKARKLDEDQPLSPSFRPTSPSFQVSSPPFRATSPSFGGSATAILDSLSKPGENSLGNLNLGTPIIGRTPVGERVMGVITSQPNSRQSSPDPRPMSGITESKRGPLTSAISASGVAEALESRARAGQIGESDLNDAAFSLNAIPDANEPSNLGEPSPSETMPTCSEKGDDDDEDEDEDDEDDDPLASAEEPMHPTEETYGYGSDDEHEPFGPDSMDEIDVEGMEMLDSDSDTEGTPYQDPDPMCLDRFSEEESDMILEEARMHGNFVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MFJ4</accession>
    <name>A0A9P6MFJ4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007145</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003600">
        <property type="protein sequence ID" value="KAF9996904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MFJ4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050849">
        <property type="entry name" value="HAD-like_hydrolase_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28181:SF1">
        <property type="entry name" value="COLD TOLERANCE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28181">
        <property type="entry name" value="UPF0655 PROTEIN YCR015C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="268"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9996904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="397" mass="44756" checksum="C05CABAB4CD690BF" modified="2023-09-13" version="1" fragment="single">NLFNFDHLVCDFDETITDHDTTSSFDALASEIRPDEYAEPQMTWPEILQAYLDDLEKVDVSDLCHLNDSLSLDTKDGALPQQNCVQAQVQDGLHRPRPRTIQPPSAKHHLLDPKVRELKCHIDGRTFTPEPEPPVPKIPSLQAWIHSQIRKRAVEKVSLDRVYESGNLVGLTKPQIREYGRNHIQLRPGMVEFLKLFVQEQDKKESEGQKRGELWILSVNWSQDLIRGAMDQIFGSEEATEKYLPESNLISSNLQFFNEDHHELVLRRRRSSAQNEDDSNGDIVAVDNKDQSDNPSSSSKADASKHLSSGKVTVHCLTGTDKLHTLQGIQRCYAAKHDVLLTDVKWAYVGDSSTDLGCLVEADVGIIVGKSKSLMTECEQSGIQVIDIEQKSLNQKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MFW7</accession>
    <name>A0A9P6MFW7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006912</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003447">
        <property type="protein sequence ID" value="KAF9997870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MFW7"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="23"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9997870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="70" mass="7118" checksum="8E8B36A3A2B00553" modified="2023-09-13" version="1" fragment="single">MSSTGNSTNLTEDQKQAQHLPIGSNSGSTQGQSGASTTNDASKESPATGEGLPQTDEPVHSIKLIGHIKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MI10</accession>
    <name>A0A9P6MI10_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transforming growth factor beta regulator 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">TBRG1</name>
        <name evidence="4" type="ORF">BGZ80_006120</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003009">
        <property type="protein sequence ID" value="KAG0001744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MI10"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003889">
        <property type="entry name" value="FYrich_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003888">
        <property type="entry name" value="FYrich_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05965">
        <property type="entry name" value="FYRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05964">
        <property type="entry name" value="FYRN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00542">
        <property type="entry name" value="FYRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00541">
        <property type="entry name" value="FYRN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51543">
        <property type="entry name" value="FYRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51542">
        <property type="entry name" value="FYRN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="90"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="297"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="337"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="23"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="41"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="91"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="354"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0001744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="467" mass="51443" checksum="0A68F9B2D94D37A1" modified="2023-09-13" version="1" fragment="single">HLLDLLSDLQQMNGSGPSSDSDTSMDDLSGLDDDEDDELREEGLGGQRHDRPGIGRTDPISKSALANKNRRVDTISGHGAQLSQDYMHVAGSTNSTGEGIENGSQANIKQTNNIPPSQAIRAGPSKRADRGRPRAVVPLPTNPDGSLNYPIVVGKGTNEVIIENMGRIVWQGRGYHNHRYIFPVGFRSKKQYTSLSDTSKKTYFINEILDGGEQPIFQITLEDMPDKVFRHTSSSGAWELALKGLMELGYNAKTHASGPDMYGLTNLGVIKYIQEMPNAHRCRRYMPLKWIIEDEDMNLPQSPNGDPAGAKSPSGRKRKINNSLYASNHEVLLETMEEQARVRSSSAPQSHIPHTPRKYTKRKTTYEQDQSSMTPAPPAPVSESESGVDPMEDVKHEIDNPNLTPMMSPSSVTSMVSVTTAASTPAIPRSLVGQEPPYPNILPVQESLRSKTPIHYENHYGQPIMEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MIS6</accession>
    <name>A0A9P6MIS6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HMG box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_006058</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002995">
        <property type="protein sequence ID" value="KAG0001891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MIS6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000779">
        <property type="term" value="P:regulation of double-strand break repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00084">
        <property type="entry name" value="HMG-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DEK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036361">
        <property type="entry name" value="SAP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13468">
        <property type="entry name" value="DEK PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13468:SF1">
        <property type="entry name" value="PROTEIN DEK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68906">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="4">
        <location>
            <begin position="181"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="1">
        <location>
            <begin position="181"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="222"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="114"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="222"/>
            <end position="329"/>
        </location>
    </feature>
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            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
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        </location>
    </feature>
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        <location>
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        </location>
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        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="539"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="562"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0001891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="562" mass="60197" checksum="D8DE112819C48B21" modified="2023-09-13" version="1" fragment="single">GKGVKLGLIPTVSANLDKLKTSDETVKGLHRFLYGRVTPSKSPKNDLKAFNGFPDLTEKDEETYEEKLGKWTVGGLRELIELFNLEEGGDKDALIERLMAFLKKPKDSGLIPRAQKLAQEAKEKKAQKVALKKAKIAAKAKKAAELKAKKAETKKLLLAKKKDALKAKAASKSSTRVSKAAPKVRSAFDMYVKAHRKEVEEASPDASRADVYKTLVDKWEAVSQSSKEEYETKAAEENAKTAEKRLQAQQEAKEAKKEKKTTTTDAAESKKTTKEKASKADKAAKTPKEKAHKADKAEKTPKEKATKADKADKADKTEKAPKEKKEKATKAAPAPAEAEKKTKAPKEKKAAAAAAATETVEKKAKTPKEKATKEAAPKEKASKEKAAKETAPKEKAAKETTPKEKATKAPKEKATEEKAPKAAAAPKEKKEKAPKAAASSTTAEAKETKEPKEKKAKATKEAKENKEEPKAAKKAAPKSKDESSEAKPKATKKAAAKSDSASSEATDAPKPKAAKAAKAEAKTAAAPVAAGKKRKADTSDAAAVATAKKPKAKAATATKEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MLE1</accession>
    <name>A0A9P6MLE1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005009</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
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            <taxon>Fungi incertae sedis</taxon>
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            <taxon>Mortierellomycotina</taxon>
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            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002499">
        <property type="protein sequence ID" value="KAG0007126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MLE1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0007126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="228" mass="25973" checksum="ED84072F6B6DF8BC" modified="2023-09-13" version="1">MFAKIYVITNEIQKPDSKVPLRCPLCKKENTLIFKYSFMLTLVDEFQQTYEVNVDNEGARTLLGPTLGNARKFSSNNERFKELKEKLARIGVTEGNPKQDQPIYFDCCIRLNGVQHSRSFVTSALPEMEHYGDDDEIEDFPYCGDEEAHYSGDDVDRGETDRYAGISTQSCEMFSQKRRASDDLKGNGKRPNNNSIKDISSNRGLHLQELDDDTTPCFRASLVFTVII</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MLW6</accession>
    <name>A0A9P6MLW6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004612</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002334">
        <property type="protein sequence ID" value="KAG0007482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MLW6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="125"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="148"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="175"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0007482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="360" mass="38208" checksum="E6E651082C1E3D54" modified="2023-09-13" version="1" fragment="single">MPPKKAAAMGSKPNKKQKLGDHVSSGAGSNDKILSKEEEEEMSSALIAQLLAQEGGGDHGYYAEYNNDANYGSLGDGDYSDDDDDYRNDYNYKPKSRSKRGARHPRKKAKHAPPPQPKPAPAAPAAPKTPAAPKAPEVPETTVDAANSSEKPVTVVSTVEPSSTQAATDTQITKPSSTSVAESTTPTPTTTQSATETPSATTTTVSTAPATATTSATPATPTAVPKAKKPKDAPVGMNTGVYSEEEERAFVEALELFGRNWKMLFRDNIPLPPRILETGPGYTLSGNDLDPYSAAARPYLSQRLLDDPSLLPAQGGTRFTPQSGAIAKAERALAKEKKATEGAKEKEIVKDTVKEMKELR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMD1</accession>
    <name>A0A9P6MMD1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004806</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002409">
        <property type="protein sequence ID" value="KAG0007323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMD1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36182">
        <property type="entry name" value="PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G10930)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36182:SF1">
        <property type="entry name" value="PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G10930)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040195715" evidence="1">
        <location>
            <begin position="19"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0007323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="208" mass="22895" checksum="8BE02A15F9E568C1" modified="2023-09-13" version="1" fragment="single">MKFATLLLIISYIAVASAHMALLYPTPRGGHGTKQYNGRVTTFIGYKDSVWKMKFPCGGYAPGPVTKMKAGQVVNVRFYSSSMSASQIKKQPKPTSVKHQFSQARHGGGTCEFSLSYDGGKTFGLIGRYTKTCPDAYFEWPVKIPSNVPSCTTKNKCLFVWSWTANILSQYYHNCADISLTGVKNGKRPTKGIQIVDFSGRKQGVKAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMG8</accession>
    <name>A0A9P6MMG8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004588</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002321">
        <property type="protein sequence ID" value="KAG0007510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMG8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="496"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="26"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="120"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="205"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="254"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="310"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="518"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="556"/>
            <end position="588"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0007510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="623" mass="68322" checksum="33363E3F54F7C1E9" modified="2023-09-13" version="1">MEDSRGGHHSYGSSHAHSHGSDRYQSHSSSSQQQHYQQQQSQHPPTSYPREGRSSSSQHQQYQDPDAGASWRSPITPTTTRRFNKMAIHEVIDSHQQQQHQHPYGYEEDSPPYKRKGSPEEFSFSDPPASSSVSHGGSGLHQSSRFWGRHYGRGDGHHQQEYHRPVSPRYRHESPLPGSNSEDDDDDIRNYKKRRFPGISGQRGGSHQSPPSSSPSGQPEVMDQVRSTLKLKQQQKALIESRQQGLPSPLPQTGNGKPSSSNGSNPPVTETTASGLSVFHGSSSFASRRPQPSPKNPKNQKSLTIFAPSYSESTLSIHSAPLQPSQSHQAMSMGLRTSQPLRNQHHPYAPQSSSIQQPLRSPRATGHIKKSSRNALRPPGVITDSSSGTIPAPILSSHTGPLPSPSMYPSTPFLSNPKHLFIETVSNLFDSVDSNRSLKYTLEEQIRKSAQLLQTLQASGTMIENLVRGQFKELEKGVIERFESEIEHLNARVQQLEEHQGLTPPPKKPKTTAKETKPTITPPTSSSAMTGVTSTSNGTTTTETASTSGVAEVSMEPTSAVTPAQRDSSSPNSGTLPTPPLTKNQDSATAMDIEDEEERDPSEYGSSVKNLQERVANLENHKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMV7</accession>
    <name>A0A9P6MMV7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004381</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002237">
        <property type="protein sequence ID" value="KAG0007669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMV7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="26"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0007669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="177" mass="20472" checksum="1F3B57619ED5A736" modified="2023-09-13" version="1">MTARTELEEPAMEAIRRKACFGPILLTETQLELQNTKDALANSERARQEANQNRVLTRPHRKQEVFVVLRFQKPQPLPVGGFRIFALQRKAVDRTLTQFVADNPELDAAEVEELRFDRSPRGENVYQQMKDDKAAPIKFSRRNFILKDGKTEDEMVAYIQQVFRTYTLENSTASTIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNV2</accession>
    <name>A0A9P6MNV2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_002947</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001752">
        <property type="protein sequence ID" value="KAG0008897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNV2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0008897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="139" mass="15095" checksum="336F2D8C0C5EA669" modified="2023-09-13" version="1" fragment="single">MYPPSTRRQPSPPSRAGPPTTHSSTRATRQQSVNPKVPPQQTQQGFSAWERGDRGSFVQHLIGNGCSAVLYNTEADVQISADCLPDNTIVSGDSDFLFYKSVAALWRPIGKHAVCEVLGLRNEGLVALAVVSRNDYANL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MP99</accession>
    <name>A0A9P6MP99_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GPN-loop GTPase 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_002756</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Binds to RNA polymerase II (RNAPII).</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the GPN-loop GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001696">
        <property type="protein sequence ID" value="KAG0009075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MP99"/>
    <dbReference type="OrthoDB" id="5839at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17871">
        <property type="entry name" value="GPN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000338">
        <property type="entry name" value="GPN-loop GTPase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004130">
        <property type="entry name" value="Gpn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030231">
        <property type="entry name" value="Gpn2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21231:SF3">
        <property type="entry name" value="GPN-LOOP GTPASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21231">
        <property type="entry name" value="XPA-BINDING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03029">
        <property type="entry name" value="ATP_bind_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="309"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="309"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU365059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0009075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="354" mass="40347" checksum="1FAE5A70C11FCF87" modified="2023-09-13" version="1">MPFAQVVIGPPGSGKTTYCNGMYQFLNGVERKTTIVNLDPANEILPYPTDISILELISLEDTMDNLQLGPNGGIIYCMEYLAENMDWLEEKLKACGDDYIVFDCPGQVELYTHNDAMKRILNRLEKIGYRLCCVHLVDSHYCTDAAKYISVLLLSLKTMLQLELPHVNVLSKVDLIETYGRLPMSLDFYTNVQDLSFLQYHLNQDPFMKKFQQLNEALCDLIEDFGLVGFETLCIKDKESVTRVIRAIDKAGGYVFGGLEEANESIFMTAMRAGSEWDTSVQDVQERYVEGYDPDEDLKRFAREYKMTEEERRDLLGSDETPRQEGHSHGDGSVIDTAEQGEVRKKKVEFDVEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPB5</accession>
    <name>A0A9P6MPB5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 9">Adenosylhomocysteinase</fullName>
            <ecNumber evidence="6 9">3.13.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">SAH1_1</name>
        <name evidence="12" type="ORF">BGZ80_002593</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>S-adenosyl-L-homocysteine + H2O = L-homocysteine + adenosine</text>
            <dbReference type="Rhea" id="RHEA:21708"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16335"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
            <dbReference type="EC" id="3.13.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8 9">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
        <text evidence="8 9">Binds 1 NAD(+) per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 9">Amino-acid biosynthesis; L-homocysteine biosynthesis; L-homocysteine from S-adenosyl-L-homocysteine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the adenosylhomocysteinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.13.2.1" evidence="6 9"/>
    <dbReference type="EMBL" id="JAAAID010001644">
        <property type="protein sequence ID" value="KAG0009246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPB5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004013">
        <property type="term" value="F:adenosylhomocysteinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033353">
        <property type="term" value="P:S-adenosylmethionine cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00401">
        <property type="entry name" value="SAHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000004">
        <property type="entry name" value="Adenosylhomocysteinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1480">
        <property type="entry name" value="Adenosylhomocysteinase-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00563">
        <property type="entry name" value="AdoHcyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042172">
        <property type="entry name" value="Adenosylhomocyst_ase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000043">
        <property type="entry name" value="Adenosylhomocysteinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015878">
        <property type="entry name" value="Ado_hCys_hydrolase_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020082">
        <property type="entry name" value="S-Ado-L-homoCys_hydrolase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00936">
        <property type="entry name" value="ahcY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004005">
        <property type="entry name" value="PRK05476.2-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23420">
        <property type="entry name" value="ADENOSYLHOMOCYSTEINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23420:SF0">
        <property type="entry name" value="ADENOSYLHOMOCYSTEINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05221">
        <property type="entry name" value="AdoHcyase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00670">
        <property type="entry name" value="AdoHcyase_NAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001109">
        <property type="entry name" value="Ad_hcy_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00996">
        <property type="entry name" value="AdoHcyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00997">
        <property type="entry name" value="AdoHcyase_NAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00739">
        <property type="entry name" value="ADOHCYASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 8 9" id="KW-0520">NAD</keyword>
    <keyword evidence="3 9" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S-adenosyl-L-homocysteine hydrolase NAD binding" evidence="11">
        <location>
            <begin position="185"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="151"/>
            <end position="153"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="216"/>
            <end position="221"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="237"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="340"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="347"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001109-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001109-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0009246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="426" mass="46562" checksum="0C7A1DAF3B0E0902" modified="2023-09-13" version="1">MADIGLAAFGRKEIELAENEMPGLIALREKYGPQQILKGARIAGSLHMTIQTAVMIETLTALGAEVTWSSCDIFSTQDHAAAAIVESGVPVFAWKGETDEEYVWCLKQQLFAFKDGNGPNMILDDGGDLTALIHDFYHELLSEIKGISEETTTGVYLLYKLHRDNKLRVPAISVNDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGSAAALKSMGARVIITEIDPINALQAAMEGYEVTMMEEAVNEGNIFVTTTGCRDIIRGEHFAAMKDDSIVCNVGQFNIEIDVAWLRENAVSHVNIKPQVDRFRLASGKHVILLAEGRLVNLGCATGHPSFVMSNSFSNQVLAQIALWTDIESYPLGVHRLPKKLDEEVAASHLAKIGVKLTKLTSEQSEYLGLSPEGPFKPEHYRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPC7</accession>
    <name>A0A9P6MPC7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_002497</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001619">
        <property type="protein sequence ID" value="KAG0009329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPC7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0009329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="282" mass="31904" checksum="5671A6E5D7CC3F09" modified="2023-09-13" version="1" fragment="single">MYEKKSLLTSDLIQLLRDHKRVWISCTLSADATNSLHQNLLRLDFNGKCITGDSDEDEKRYISQNIDTLGELDYFIHTPTICVGIDYSNKDSKFDYVVGFFSTHSGVNVETSRQMMRRVRHVTSKIYLIYVDKATSNLPTTKEAIKDWICNQENIVSGAVRDLSGLSFRADYGKGLRLIDSFYSQVYINTAIKNNLSANGFMQRFIQQMVHAGCTVRGAQGGSIEGTQILKLQKETRKGIEWERCKRIATAESLTQDAFEELSNVEGLAPEAKDAVARHRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPS7</accession>
    <name>A0A9P6MPS7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small ribosomal subunit protein uS9m</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">37S ribosomal protein S9, mitochondrial</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">MRPS9</name>
        <name evidence="7" type="ORF">BGZ80_002824</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the universal ribosomal protein uS9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001716">
        <property type="protein sequence ID" value="KAG0009019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPS7"/>
    <dbReference type="OrthoDB" id="10254627at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000001">
        <property type="entry name" value="30S ribosomal protein S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00532_B">
        <property type="entry name" value="Ribosomal_uS9_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000754">
        <property type="entry name" value="Ribosomal_uS9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023035">
        <property type="entry name" value="Ribosomal_uS9_bac/plastid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020574">
        <property type="entry name" value="Ribosomal_uS9_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001099">
        <property type="entry name" value="PRK00132.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21569">
        <property type="entry name" value="RIBOSOMAL PROTEIN S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21569:SF1">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US9M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00380">
        <property type="entry name" value="Ribosomal_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00360">
        <property type="entry name" value="RIBOSOMAL_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6 7" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00039318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00042623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0009019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="280" mass="30770" checksum="BEE42E14098531F0" modified="2023-09-13" version="1">MRTSLGSIAQTTCIRSMSSVSPPNVTSAQVPPTSGYESLSGFQLKPASPSYFTTNPVYNELIVNLDYTYSQYRPVTKPSKTAQRPNWLNKDALTVAVGVDALKTSQYRLIISKLNQLATLTPRPSAIEAIFSQFSKSEEQLSQKAKPRIVDHLGRALATGRRKEASASVYVVEGDGKVLINGQDSSQYFKKSQDRDSVLKPFKATNLLGKYNVWALVKGGGTTGQAEAISLGVAKALLTHSPELKPTLRKAGCITRDMRVVERKKPGQYGARKKFQWVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQ49</accession>
    <name>A0A9P6MQ49_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">40S ribosomal protein S6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RPS6_2</name>
        <name evidence="4" type="ORF">BGZ80_001948</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eS6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001465">
        <property type="protein sequence ID" value="KAG0009904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQ49"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.2650">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001377">
        <property type="entry name" value="Ribosomal_eS6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018282">
        <property type="entry name" value="Ribosomal_eS6_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11502">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01092">
        <property type="entry name" value="Ribosomal_S6e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01405">
        <property type="entry name" value="Ribosomal_S6e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00578">
        <property type="entry name" value="RIBOSOMAL_S6E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0009904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="161" mass="18248" checksum="67306CFBF2281933" modified="2023-09-13" version="1" fragment="single">MKLNIANPATGCQKTIDFDDERKTRIFYDKRISAEVAADSLGDEFKGYVFRITGGNDKQGFPMKQGVLLPSRVRLLLSKGHSCYRPRRTGERKRKSVRGCIVGSDMSVLSVSIVKQGEQDLPGLTDTNVPKRLGPKRANNIRKFFNLTKDDDVRKFVIRRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQ64</accession>
    <name>A0A9P6MQ64_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nuclear cap-binding protein subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_002197</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001534">
        <property type="protein sequence ID" value="KAG0009647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQ64"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000340">
        <property type="term" value="F:RNA 7-methylguanosine cap binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019416">
        <property type="entry name" value="NCBP3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16291">
        <property type="entry name" value="NUCLEAR CAP-BINDING PROTEIN SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16291:SF0">
        <property type="entry name" value="NUCLEAR CAP-BINDING PROTEIN SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10309">
        <property type="entry name" value="NCBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="358"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="376"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="425"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0009647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="510" mass="57544" checksum="6F2536241027D035" modified="2023-09-13" version="1" fragment="single">MDFDVDQYAIPGEDLDIDLTLAQPDPASAPATSNNNFRDSMLELEQSLEEQTRDISSRFQSERRPEPAGLDRALDDNYGSSNQRSRVDTSAQQRYASKSGGFVTGFDPLSKEEQAKKATRAQRFGALPQEETQNKDSGMDEQGASMDVDDGEWIRPDNLPETPPRTSTIRLEAVHLYGTDEMSTKDVLSYFDAYGPSHVEWIDDSSCNVVFPDQFSAKRALYFQLVNRDVNFGEEAENDVEPSRTESVTPADESGTPAAVVAPKSNNRLQRAKDYIPVQQQNHPIIQSNKGLFVRYATDYDRKERGAAARSTYYAIHGREEARSGHINNSLGSSRYGRRSRADDDEIWNRGRGITSFSRLRRKMENGGESPSPSPTRHRSWSRNRRLGGSRSRSRSHSRSRGGSRSPGSYSSRRDRASLSPDSNNRMRSDDYEKRGRRGDISLRLGGRVKFPDAADEEATETRLNQYADDFLAELESSFSRREKAIPKTKMYSDFYEREILSEVPSDSRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQE9</accession>
    <name>A0A9P6MQE9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_002478</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001612">
        <property type="protein sequence ID" value="KAG0009358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQE9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0009358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="122" mass="13901" checksum="316552413020F541" modified="2023-09-13" version="1">MIDDLKMSMDQQVAGFEKKMAEQEEIAAENKDFRIQVGILIGEQDSGTDKEHKGEEGRNEERRLVHGGLWQSILSSSCNSPKKDRHATKAPRVPAIELMSYTDWELNTVLMLMNSYLDFNVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQG4</accession>
    <name>A0A9P6MQG4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Carnitine O-acetyltransferase mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">CAT2_2</name>
        <name evidence="8" type="ORF">BGZ80_001918</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the carnitine/choline acetyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001458">
        <property type="protein sequence ID" value="KAG0009929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQG4"/>
    <dbReference type="OrthoDB" id="240216at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004092">
        <property type="term" value="F:carnitine O-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009437">
        <property type="term" value="P:carnitine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.70">
        <property type="entry name" value="Choline/Carnitine o-acyltransferase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000542">
        <property type="entry name" value="Carn_acyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039551">
        <property type="entry name" value="Cho/carn_acyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042231">
        <property type="entry name" value="Cho/carn_acyl_trans_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22589:SF103">
        <property type="entry name" value="CARNITINE O-ACETYL-TRANSFERASE, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22589">
        <property type="entry name" value="CARNITINE O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00755">
        <property type="entry name" value="Carn_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00439">
        <property type="entry name" value="ACYLTRANSF_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00440">
        <property type="entry name" value="ACYLTRANSF_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Choline/carnitine acyltransferase" evidence="7">
        <location>
            <begin position="22"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="717"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="730"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR600542-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0009929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="796" mass="88834" checksum="744335E4DBEA8601" modified="2023-09-13" version="1">MPVDSMNDVCIMDKGQDQLPSLPIPPLDQTLTRYLESVRPLTSDAEYDRMAESISKLKESGQGQDLDQRLRDHAKNCEQRGTSWLAEWWDEWAYFTHRDSSTFFVNYYFGFQDDVRMPTQTARAALLVSLALEFRQLIATRTLTPDMARNAPFCMNMYNYLFNYSRISGPNADSAVGFPTETNNHICVVRNGKFYIFETLHLPSKPSSVLSPREIMIQLERIKKMADDDASSVPAVGILSTGQRDQAAKDRATLFEAHASNKAHMAKIETSMFVLCLDSSSPSTSEEFSRACWHGDGASRWFDKCFQLIVFANGRAGMNGEHSKMDATPTSRLCRYLIDEAQARPLPDFRNLNAEDLYECASALDKPLPLKFISSPALERAIANAYTYFNDTVAAHEMVPTEYKGYGKGLIKTFKMSPDAYVQMALQLAYYRKHKELVATYESAATRKYRHGRTETVRSCSNESKAFCEAMDNPDVSFKVRANACRAAVARHAQYTAWAVDGQAVDRHLLGLQLIRKPDEEVPAMFADPVFKRTCRWRLSTSQISDDCFIAYGWGEVVPDGYGCAYMVKESELYFCVTSLKLGSKDFGQHIVDALEDMRFTFEQARKIEKAEAAQAAMLAAAAEALSHAERTTELVMASHGLNTSPGGGRFHDERFSVPAYAMSRSPSPGRLQLPAPRTSLFFQKHDPVLRTALARSALAMEQEKYLSGIDEIAFDDIAGSPRPQNKTISSSETSPPTSPVKSTGGENGRPRSDSGSTQVRTFMAILMGEDGIITRLRSRRGSNLNSKKTSPPSSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQS5</accession>
    <name>A0A9P6MQS5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Alpha-n-acetylglucosaminidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_001462</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001334">
        <property type="protein sequence ID" value="KAG0010464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQS5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.379.10">
        <property type="entry name" value="Chitobiase/beta-hexosaminidase domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.670">
        <property type="entry name" value="N-acetyl-b-d-glucoasminidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029018">
        <property type="entry name" value="Hex-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007781">
        <property type="entry name" value="NAGLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024732">
        <property type="entry name" value="NAGLU_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024240">
        <property type="entry name" value="NAGLU_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024733">
        <property type="entry name" value="NAGLU_tim-barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12872">
        <property type="entry name" value="ALPHA-N-ACETYLGLUCOSAMINIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12872:SF1">
        <property type="entry name" value="ALPHA-N-ACETYLGLUCOSAMINIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05089">
        <property type="entry name" value="NAGLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12972">
        <property type="entry name" value="NAGLU_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12971">
        <property type="entry name" value="NAGLU_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha-N-acetylglucosaminidase N-terminal" evidence="3">
        <location>
            <begin position="119"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-N-acetylglucosaminidase tim-barrel" evidence="2">
        <location>
            <begin position="234"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-N-acetylglucosaminidase C-terminal" evidence="4">
        <location>
            <begin position="599"/>
            <end position="895"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0010464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="909" mass="102976" checksum="138774E4A9A1E9CE" modified="2023-09-13" version="1">MNDVTPDLYVANVPWKYLLRGIGWTRRYAIRVAAEFHADNVEKIMTWYKQAVAAVKQATGTGQVTRVVIPTMAKKVGSLPSWAKLGLAAGVLLQVVAPGNLALAAPTPKAGNGADPLLGVVQRLLPKSYHNAFDFQLVSDIPTPSPENKYDVFRVSNKNSTSSSGKILIEGATLSALGRGLKYYLDQAVQVELAWSGNRFDELPHTPPSVPDLELDTNKVVTTGHVRGSFVPWRYYTNVVTYGYQFPFWEWARWEREIDWMMLNGINLLPAMVGQEYIVREFWRSKNLTDAEIIDFLTGPVDMPWQRMGNLQGSWNHQLLNSSIENERVYKNMWIDAQWELQKLIMARIQDLDIIPILPAFQSFVPRATVAKYPNNQFKNASVWSYFPEEYTAVTYVMQTDPLFTTFSVEYLELQKSLYNGYESHLYLLDLFNELVPDCTTPECLRSISTNVMKTLQSADKDAVWVMQGWFLQDTTLWTPDAMKAYFGGISDANGDTFIMDLAADTMPTWTSTEGFYGYNFGWSVINNFGTAQGLFAKLPIVLTAAFDAYKQYPAGLKAIGVAAEGINNNEYVYQTVFELPWHNPNEVINGTSLLEQNIQRRYGPSRATPIVQDAWNKLRQTVWDCQVQNQASQSKSYVEKMPDLNMVNNGWLGTVFWYNKTIVVEAWDQLVRAATTEQHFNIPDSFKFDLVDTTREVLLATVFTALHDGLVDGYQANDVKKIQEYGRRIVALIKDADTLLNTSPFFSFGAWVLAAKTSIDPINGNIDKQLKFNSNSPGGPNKAEYLHFLESNARDIFTWWGPDGTGPPDALPDYASKQWGGMLTSYYLPRWQLFISQLEESVKTKKAWNRDDYITQAVAREAQWLKQTWGQRPGETWETNGQESVEVVRELHEKYSKLAFKIAASGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRD2</accession>
    <name>A0A9P6MRD2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Sphingosine-1-phosphate lyase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_001150</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001258">
        <property type="protein sequence ID" value="KAG0010831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRD2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008117">
        <property type="term" value="F:sphinganine-1-phosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030149">
        <property type="term" value="P:sphingolipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050477">
        <property type="entry name" value="GrpII_AminoAcid_Decarb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42735">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42735:SF6">
        <property type="entry name" value="SPHINGOSINE-1-PHOSPHATE LYASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="30"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0010831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="230" mass="25832" checksum="8373351D775152CB" modified="2023-09-13" version="1">MPISSVLASPASQLIQTYLNNPRLSNVKNLVFIIFIFKLLSFLNTTFLVHGPSRTYREAKMYLSILAFKYAKMIPSVKEKLQRELGKAAKDIEDKVAPQDDKFPRYTTLPGHGFSEEALTKELERYSELPHTRWEEGRVSGAVYHHNKILSDLGALAYRKFSSANPLHPEVFPGTRKMEAEVCAMVADLFHAGPQAGAVMTSGGTESILMSCKTHREWGRETKGITKPEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRJ0</accession>
    <name>A0A9P6MRJ0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Serine/threonine-protein kinase ATG1</fullName>
            <ecNumber evidence="4">2.7.11.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">Autophagy-related protein 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Serine/threonine-protein kinase atg1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="23" type="primary">ATG1</name>
        <name evidence="23" type="ORF">BGZ80_001028</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="23" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="23">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Preautophagosomal structure</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="4"/>
    <dbReference type="EMBL" id="JAAAID010001228">
        <property type="protein sequence ID" value="KAG0010988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRJ0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005776">
        <property type="term" value="C:autophagosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034045">
        <property type="term" value="C:phagophore assembly site membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010506">
        <property type="term" value="P:regulation of autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042594">
        <property type="term" value="P:response to starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061709">
        <property type="term" value="P:reticulophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14009">
        <property type="entry name" value="STKc_ATG1_ULK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000399">
        <property type="entry name" value="Serine/threonine-protein kinase atg1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045269">
        <property type="entry name" value="Atg1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048941">
        <property type="entry name" value="ATG1-like_MIT2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022708">
        <property type="entry name" value="Atg1-like_tMIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24348:SF22">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24348">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE UNC-51-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12063">
        <property type="entry name" value="ATG1-like_MIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21127">
        <property type="entry name" value="ATG1-like_MIT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="13 20" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="15" id="KW-0072">Autophagy</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12 23" id="KW-0418">Kinase</keyword>
    <keyword evidence="16" id="KW-0472">Membrane</keyword>
    <keyword evidence="11 20" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-0653">Protein transport</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Protein kinase" evidence="22">
        <location>
            <begin position="17"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="259"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="313"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="460"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="21">
        <location>
            <begin position="344"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="21">
        <location>
            <begin position="382"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="21">
        <location>
            <begin position="405"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="21">
        <location>
            <begin position="462"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="21">
        <location>
            <begin position="545"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="23">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00019599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00030237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="KAG0010988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="810" mass="89431" checksum="8AE2FB83C1057ECD" modified="2023-09-13" version="1" fragment="single">MATTAKPVPEVNLVGDYIVEHEIGRGSFATVYKGHHRITKESVAIKSVLRSKLTKKLLENLASEINILKGIRHDHIVALVDCKETESHIHLVMEYCSQGDLSQYIKRGGDGPPSLPSPPGGGLHEVVVRHFLKQLASALEFLRSKNLIHRDLKPQNLLLHPPSNSKEGSGYGLPVLKVADFGFARSLPRLSLAETLCGSPLYMAPEILHYEKYDAKADLWSVGTVLYEMCTGKPPFRAHNHVELLKRIEQAQDVITFPGDNVAGDRAGSSTSQRHHHSTVTISEDIKDLIRQLLKRNPVERISFEEFFMNPTVSNSPLRSRSRSSRSSSSTQDYSRYEVQSGDLTRRLSVHDPSRHSHDSGQRERGERKPISIPATGREQGENSVPVNTSARRMKSMEIPANRALTPQPSSQPYRRSTLVGVPDVSPRHNVPEDDALLDKDYVVVEKRAVELNVLADEVAASPSSNSNRAKSGSGQNNTLSPPIPASLTQYRTPPPPYGSYPYSTSTPSPPANANYFSTTPPFALPAASTPEEPRSIQAVHRPSLGQNQPQASPISARSGSPRDGSKTSALAKAISMASMRLFGASSSPPSWKSNTPLIGFMDSPSRNSGVLEVDPEENTVLQSIEDTAHKAYVISQFADSKMEGSRPLDELDYSPSEDHEPSRGSILAEEAFFLYLRALALLQAGMNVARQYWEERRQESKPASTRLNNGVQWIRDRFNECLEKAESAKVRSGIDNREESGVVIEKLIYERALELSKAAAMKELASDDYGESERSYQTSIWMLHAILDGAGEDGRSEAIEEDDREILNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRT6</accession>
    <name>A0A9P6MRT6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_000879</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001197">
        <property type="protein sequence ID" value="KAG0011165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRT6"/>
    <dbReference type="OrthoDB" id="2372290at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0011165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="293" mass="32801" checksum="BA72E683A762F962" modified="2023-09-13" version="1">MYPARTNCISDSVDNVIRRVDELEKRLNEISLLTNNDPAGEPASEEEEDSPIIQPERTSQITADTTSTLPSMDIATDSSGLPAYNDVKSSELVRLRNKIECAKNALFDSMVQSGSCTLKPLPPTIPSPGHDDIFVVWCMSQSRDKYKRALVKIIEELQVQEEKEWMTFILSKAHTQDSDDSLYRKHLRAKIEAAKRAVINYHIKRIAGTSKDSRIPGILPNASSHGVDVDVLVIGCLRTPGFDGFVHNDGSVNYCMDPFDSKIGSLITKLLKKEDEEMERLLQLKASNKEEKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRV0</accession>
    <name>A0A9P6MRV0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PB1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_001183</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001265">
        <property type="protein sequence ID" value="KAG0010787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRV0"/>
    <dbReference type="OrthoDB" id="661148at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05992">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053793">
        <property type="entry name" value="PB1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000270">
        <property type="entry name" value="PB1_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00564">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00666">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54277">
        <property type="entry name" value="CAD &amp; PB1 domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51745">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PB1" evidence="2">
        <location>
            <begin position="5"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="248"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="309"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="426"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="97"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="329"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="426"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0010787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="456" mass="50185" checksum="8BB40957FD128EE4" modified="2023-09-13" version="1" fragment="single">MDPQQSICKVSLKGALRRFLVARPAVWRDFEDKIRTVYNLPPDTALDVEYKDEEGDVITLNTDSELEDVLAMHALFNQLAPVKFDVTVGEQLTQQEQQQQEQQQEQQQEQQQEHQQEQRQEQQLPTIAQEHPQFTSWRLSNHDQAYNNLQVDLASTVTTESILSPKHSGSLCGSEESDDVSLIDLEEGTESRLGEEYHNAEPSEAMDDQTINYPQRDLVEAAKLQEKLEAYKLDAPVFKSSLDLGQSVSSHSSQQTESSSSAANSATTAMAVPHASTVPSFASVPFPEFEAMHINDAQVAVEPTVTPVVEQPTDAKEESETETETEQKAPSTPTASVSTSEKQAQDDERALIEQFQQLIKEFQEVIQNNPQLVALASGIMNKVMSNVKVNMESFAGFLQTQAQTAQEVASQAAAQAQEAATQAQDLANQAATRAQETASKVRTGPFGMNSSGAANT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSS0</accession>
    <name>A0A9P6MSS0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Nucleolar protein 56</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">NOP56_1</name>
        <name evidence="9" type="ORF">BGZ80_000877</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required for 60S ribosomal subunit synthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NOP5/NOP56 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001196">
        <property type="protein sequence ID" value="KAG0011171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSS0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031428">
        <property type="term" value="C:box C/D methylation guide snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.246.90:FF:000001">
        <property type="entry name" value="Nucleolar protein 56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.4070:FF:000002">
        <property type="entry name" value="Nucleolar protein 56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.4070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.90">
        <property type="entry name" value="Nop domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045056">
        <property type="entry name" value="Nop56/Nop58"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012974">
        <property type="entry name" value="NOP58/56_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042239">
        <property type="entry name" value="Nop_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002687">
        <property type="entry name" value="Nop_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036070">
        <property type="entry name" value="Nop_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012976">
        <property type="entry name" value="NOSIC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10894">
        <property type="entry name" value="NUCLEOLAR PROTEIN 5 NUCLEOLAR PROTEIN NOP5 NOP58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10894:SF0">
        <property type="entry name" value="NUCLEOLAR PROTEIN 56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01798">
        <property type="entry name" value="Nop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08156">
        <property type="entry name" value="NOP5NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00931">
        <property type="entry name" value="NOSIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89124">
        <property type="entry name" value="Nop domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51358">
        <property type="entry name" value="NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Nop" evidence="8">
        <location>
            <begin position="293"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="425"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="452"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="467"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="477"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00040742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00056216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0011171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="490" mass="54888" checksum="0CF64E52E1879624" modified="2023-09-13" version="1">MVNYFLFESSSGYALFERLESEEIGSKLADVCAAATDLTKFGKVVKLKSFAPFKSAAHALENMNDVSEGIMNDHLKAFLEMNLPKPGKKSKVVLGVTEKSLAGSIKEGLGIECDASEIVLDLVRGVRLFGDKLLKQLKDGDLERAQLGLGHSYSRGKVKFNVHRSDNMIIQAIALLDQMDKDVNTFAMRIREWYSWHFPELVKIVNDNYKYARLAQLIKNKSDLSESKLEALEEITGDAAQAQQIIDAARASMGTDISEIDMINIENFAKRVIDLADYRKKLHEYLISKMNNVAPNLSALIGEMVGARLISHAGSLTNLSKYPASTVQILGAEKALFRALKTKGNTPKYGLIYHSSFIGRAGTKNKGRISRFVANNELPTTKFGEAMKEQVEERLEFYESGATPSKNADTMKKVIDSLKDAGDVDMEEVTPKAGKKRAAEEDKSSSKKAKKEKSEKEEKKEKKEKKEKKEKEEKKEKKEKKEKKEKKEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTC3</accession>
    <name>A0A9P6MTC3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_000132</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001021">
        <property type="protein sequence ID" value="KAG0012200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTC3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008709">
        <property type="entry name" value="Neurochondrin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13109">
        <property type="entry name" value="NEUROCHONDRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13109:SF7">
        <property type="entry name" value="NEUROCHONDRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05536">
        <property type="entry name" value="Neurochondrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0012200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="409" mass="45977" checksum="8857BEEFF88A77F5" modified="2023-09-13" version="1">MLSSSDETENSKKILKILIRISAYPQISMILTNARYQSIIVKFILDTFDRKDETHDDATLVCKRTFLIIHEGYKQNPEVVLKITKDFLPTIMTNLSKPFCALAEAHKPEILRLMTDSVAYLPEAYVQQHVKECPKESKIWIKNLKSGLIQLLSTRQAPATRDDSFKLIGFLLQRLGPEWIFPQISLEAVTKSTSASPKKKPSPASLLASMETLSLSDVDVDKKFASLVVHLTCVEMRVLMDQLADDLTPADERTNKGVFTTEDEANQEKTRKEQVLPLTYEILEVSIGYLVRVSESEDSLENGLFDATGILKIQESLQGAFAAILDYLKDLQSSVDASPQTLASNMVYLASLRILSVWLMEDDSLHAQAASLVPPLEAVVRYCKSKSSRKSLLRLLEPILDRFHELSLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTE1</accession>
    <name>A0A9P6MTE1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_011447</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000920">
        <property type="protein sequence ID" value="KAG0012890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTE1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006753">
        <property type="term" value="P:nucleoside phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019693">
        <property type="term" value="P:ribose phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11839:SF1">
        <property type="entry name" value="ADP-SUGAR PYROPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11839">
        <property type="entry name" value="UDP/ADP-SUGAR PYROPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="2">
        <location>
            <begin position="58"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0012890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="225" mass="24896" checksum="8CA09EB94A610555" modified="2023-09-13" version="1">MSKLERELANIKITSEEKRGNGRWLSLHEVKFTDPSGTERSWEVCRRTSSSKQAPNTPSVDAVDLITIVKNKQGQATHVALVVQYRPAMGAYTIEFPSGLFDANEEASKAALRELEEEVGFSTKLGHSVQVVKTLGPIAYEPGMTNSCSQVVVIEVTMEQHELFGPDSTRKPKLEDDEWSLQVAILPLQGLLKSLHELQSSAGGHSKLVLDSRLYAWAIGREMGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTG0</accession>
    <name>A0A9P6MTG0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transcriptional activator HAP2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">HAP2_1</name>
        <name evidence="8" type="ORF">BGZ80_000152</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Heterotrimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the NFYA/HAP2 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001025">
        <property type="protein sequence ID" value="KAG0012175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTG0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001289">
        <property type="entry name" value="NFYA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12632">
        <property type="entry name" value="TRANSCRIPTION FACTOR NF-Y ALPHA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02045">
        <property type="entry name" value="CBFB_NFYA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00616">
        <property type="entry name" value="CCAATSUBUNTB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00521">
        <property type="entry name" value="CBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51152">
        <property type="entry name" value="NFYA_HAP2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="85"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="104"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="130"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="142"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="164"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0012175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="175" mass="19976" checksum="E9BD3214EC2D39C1" modified="2023-09-13" version="1" fragment="single">MVPQGYVIGQVAARVEEPEEPLYVNAKQYHRILKRRAARANLEAQNRLMQRGRKFMHESRHLHAMRRPRGPGGRFLTAAEIAALESKSTTDDDENTTNDTQTNQHHHHHQQQQQQRHQHHNNNNNNNNNSSNPHGYSQDRYSSSTTTSTSTNPRHAVSPESDQRYGSASRTGIPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTK8</accession>
    <name>A0A9P6MTK8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pumilio 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">PUM2</name>
        <name evidence="4" type="ORF">BGZ80_011361</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000902">
        <property type="protein sequence ID" value="KAG0013026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTK8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003730">
        <property type="term" value="F:mRNA 3'-UTR binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000288">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033133">
        <property type="entry name" value="PUM-HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001313">
        <property type="entry name" value="Pumilio_RNA-bd_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12537:SF12">
        <property type="entry name" value="MATERNAL PROTEIN PUMILIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12537">
        <property type="entry name" value="RNA BINDING PROTEIN PUMILIO-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00806">
        <property type="entry name" value="PUF"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00025">
        <property type="entry name" value="Pumilio"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50302">
        <property type="entry name" value="PUM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50303">
        <property type="entry name" value="PUM_HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PUM-HD" evidence="3">
        <location>
            <begin position="1"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="2">
        <location>
            <begin position="26"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="2">
        <location>
            <begin position="62"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0013026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="186" mass="20259" checksum="C147DBA2997EEA2E" modified="2023-09-13" version="1" fragment="single">DQYGNYVIQHILERGRSVEKSLVISKVLGQVLPLSKHKFASNVVEKCVAFGSKSDRQKLIEEVIVSKPDGSPSPLVLMMKDQFANYVVQKMLDVVDGEQRDVLVAKIKPHLPSLKKYTYGKHLITKVEKLMTMQEPRSALDSFISSPALSVGTLTPTPGSPVVVPKPMTPAGAAAAPMTFATKTEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTP5</accession>
    <name>A0A9P6MTP5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PRA1 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_011250</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Membrane</location>
            <topology evidence="1 5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PRA1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000883">
        <property type="protein sequence ID" value="KAG0013167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTP5"/>
    <dbReference type="OrthoDB" id="63113at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004895">
        <property type="entry name" value="Prenylated_rab_accept_PRA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19317">
        <property type="entry name" value="PRENYLATED RAB ACCEPTOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19317:SF0">
        <property type="entry name" value="PRENYLATED RAB ACCEPTOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03208">
        <property type="entry name" value="PRA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="91"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="145"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0013167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="194" mass="21459" checksum="9928651BD922B1D2" modified="2023-09-13" version="1">MSAPTYAPVPTTSRPLPSPPLPATPSPFPHITQSPYTALGLGYIKKFREEYLSSLRPFSEFLDINRLSKPDGFATVIARLNYNLSYFQSNYMLVFLGITAYSVINNTMLMFSTGFVTAGMYFISKVPQEGIIIGLNRYNPRQLQTGLVCVAVPMFFFSSTIGTIFYIVGASAVSILGHAAFMQEDFEGDFTNIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTS9</accession>
    <name>A0A9P6MTS9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PAS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_011481</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000928">
        <property type="protein sequence ID" value="KAG0012831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTS9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAS" evidence="2">
        <location>
            <begin position="16"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="2">
        <location>
            <begin position="170"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="304"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="332"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="517"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="304"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="332"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="375"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="410"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="517"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0012831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="562" mass="63302" checksum="D27E650EF2E46AAB" modified="2023-09-13" version="1">MFQIDNFIAFHDLTPEAQFLWASSSIVNCLGYEPDEVVGMNAYDAIHKDDIAYVKITHTESVLNEMVGTQLLLRMKHKNGTYVPCMVLFSLCYEFIVSCYTIVDQSEGVMRKVSAHSAAMTSLVGSKKQEFERIRRHHQAFRANTWNAASLALEPRACMLLNRFTRNLSIMYASPSCQLIFGFDPDDYIGKPFLLYIRADDLISFVEQVEAAKSSTVVTHMRFWFQSPVYRKEIPCEAMLFGAADGLIVILRRCKPFSRRQLITGGVPTDYFASESSVSSSISSSYCSSSFNKHSGRSHSIDFSCTSNSNNGNNNGYSDSSRVIKRRSYTSSHNYNGSTCGPSSYNESYNESHNESHCNNNDSDYYHKSPSVGRDNNNNNDNNNNNNNNNNERQQKVYYIDRNNRRKSHTASTLVNSPTDSLASSYSSTMSGDSAYQSGTRAYRAPLRGVPIGSINSIRNLDNEHNRLRPLTSLHDDESDIVDSATTLPEIYRLRKHQIQVSELDETGLEIGIQDLDISDDEEEEGNNGVIVISDDDDVEEVLMPPPPRRRKEVKGDERKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUC3</accession>
    <name>A0A9P6MUC3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Crossover junction endonuclease MUS81</fullName>
            <ecNumber evidence="14">3.1.22.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">MUS81</name>
        <name evidence="17" type="ORF">BGZ80_011281</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single-end invasion (SEI).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="14">Interacts with EME1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 14">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the XPF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.22.-" evidence="14"/>
    <dbReference type="EMBL" id="JAAAID010000890">
        <property type="protein sequence ID" value="KAG0013115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUC3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048476">
        <property type="term" value="C:Holliday junction resolvase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048257">
        <property type="term" value="F:3'-flap endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008821">
        <property type="term" value="F:crossover junction DNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006308">
        <property type="term" value="P:DNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031573">
        <property type="term" value="P:mitotic intra-S DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031297">
        <property type="term" value="P:replication fork processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000712">
        <property type="term" value="P:resolution of meiotic recombination intermediates"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21036">
        <property type="entry name" value="WH_MUS81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20074">
        <property type="entry name" value="XPF_nuclease_Mus81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000307">
        <property type="entry name" value="Crossover junction endonuclease MUS81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10130:FF:000003">
        <property type="entry name" value="Crossover junction endonuclease MUS81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.110:FF:000001">
        <property type="entry name" value="Putative Crossover junction endonuclease MUS81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.670">
        <property type="entry name" value="Crossover junction endonuclease EME1, DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.110">
        <property type="entry name" value="DNA polymerase beta, N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027421">
        <property type="entry name" value="DNA_pol_lamdba_lyase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042530">
        <property type="entry name" value="EME1/EME2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006166">
        <property type="entry name" value="ERCC4_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010996">
        <property type="entry name" value="HHH_MUS81"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033309">
        <property type="entry name" value="Mus81"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047417">
        <property type="entry name" value="WHD_MUS81"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047416">
        <property type="entry name" value="XPF_nuclease_Mus81"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13451">
        <property type="entry name" value="CLASS II CROSSOVER JUNCTION ENDONUCLEASE MUS81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13451:SF0">
        <property type="entry name" value="CROSSOVER JUNCTION ENDONUCLEASE MUS81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02732">
        <property type="entry name" value="ERCC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14716">
        <property type="entry name" value="HHH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21136">
        <property type="entry name" value="WHD_MUS81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00891">
        <property type="entry name" value="ERCC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47802">
        <property type="entry name" value="DNA polymerase beta, N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="Restriction endonuclease-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 14" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10 14" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="11 14" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 14 17" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="8 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13" id="KW-0469">Meiosis</keyword>
    <keyword evidence="5 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 14" id="KW-0540">Nuclease</keyword>
    <keyword evidence="12 14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ERCC4" evidence="16">
        <location>
            <begin position="498"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="79"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="213"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="213"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="264"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="292"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="316"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="364"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="383"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="428"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU369042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0013115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="797" mass="89122" checksum="E04E148E4724B83C" modified="2023-09-13" version="1">MQCGNPLYLEWIGEWMETARENNNQAYFIYRKAYESMAKYPTRFSHPSEAMCLSGIGEKIAAKLEKKLIEYCKDNDLPMPTPKSHAPRAKAKVNVPADQGEDEPKPKKARQRAYKPYIPTYRSGAYAILLALLDASTVSADGSLTKYEITTMGQIHCDVSLTNPEHGKFYTGWSSMKTLLDKSLVYRSSSKFYLTEEGTDMAKRLRAVASETESTLLPSSDTGEQNSLPNASTSQWESRIMDWSRDTPTSIDGAKERALYRAPGSTTPFDSVSTASTNTPQDTPVNTNDSYTYDDDDFDGWDDTPSSRESLSSSSAAPTTPKNINPTAKAATSSSRTLEGNRDQPVNIISDSEDEKDGMLIETSSSSSLSRVSSSSKMEGLEAQNSEHLMANPTFTSSGLRRAPSLFKLPTRPATTTQTFNRPEPTTYRHSTSDGFLSSKSTDSLLSNDPRSHHDSFPHLKSNSIALARSDSSSGLTDIKRLARFQPIKFIPGTFEICLVLDIREVRTQTDRDYLGQKLKDRGVNVTKRALDVGDVIWVARLKDPSFDGPDEIVLDYIVERKRMDDLVYSIKDGRFTEQKFRLKRSGLGHVIYLVETHRLGEVYEIGADAIRTATTAIQIHDNFFLRRTNHTDHTIDYLVSVTNALKRLYEYKASPKIYLCKSETLFAIPDAIVNRNTYLDLQRELKESYPDRTYLTSYRSFSILNGKSETIVVKDMFVKMLMTIRGVSSEKAMEIARIYKTPRGLFSALEKTGDLTSSAHGKGSLAKSGSNVHKKRKISPALSAKIAGIWYADEYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUF8</accession>
    <name>A0A9P6MUF8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Trehalase</fullName>
            <ecNumber evidence="5">3.2.1.28</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Alpha-trehalose glucohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">NTH1_2</name>
        <name evidence="8" type="ORF">BGZ80_010656</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>alpha,alpha-trehalose + H2O = alpha-D-glucose + beta-D-glucose</text>
            <dbReference type="Rhea" id="RHEA:32675"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15903"/>
            <dbReference type="ChEBI" id="CHEBI:16551"/>
            <dbReference type="ChEBI" id="CHEBI:17925"/>
            <dbReference type="EC" id="3.2.1.28"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the glycosyl hydrolase 37 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.28" evidence="5"/>
    <dbReference type="EMBL" id="JAAAID010000765">
        <property type="protein sequence ID" value="KAG0014095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUF8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004555">
        <property type="term" value="F:alpha,alpha-trehalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005993">
        <property type="term" value="P:trehalose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001661">
        <property type="entry name" value="Glyco_hydro_37"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018232">
        <property type="entry name" value="Glyco_hydro_37_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011120">
        <property type="entry name" value="Trehalase_Ca-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23403:SF6">
        <property type="entry name" value="CYTOSOLIC NEUTRAL TREHALASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23403">
        <property type="entry name" value="TREHALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01204">
        <property type="entry name" value="Trehalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07492">
        <property type="entry name" value="Trehalase_Ca-bi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00744">
        <property type="entry name" value="GLHYDRLASE37"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00927">
        <property type="entry name" value="TREHALASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00928">
        <property type="entry name" value="TREHALASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Neutral trehalase Ca2+ binding" evidence="7">
        <location>
            <begin position="94"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="42"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="49"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="61"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0014095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="769" mass="88850" checksum="6AC72F6CDCB6583F" modified="2023-09-13" version="1">MTEKPTRIKMTDALRMPPPPSTTVVPASEYYANANYARQRTLSVSGKGTAQTTDTSALTDSDTKYRRQRRGSHDDKTIKPRRFLIDVEETQRLILEQEDTDGDFQITVNDIGPKVITLGTADSAGFNKYDVRGTYMLSNLLQELSLAQDYGRKYVVLDEARLNENPVDRLSRMIRHHFWDGLTRRIDAEGLETISNDPKNRSKNTAPRIYVPFGEQEVLDYYNNVKISKPSLHLEVEQLPQEITPKYVQSINEKPGILALAMTKHINEDGTETLKGVPFVVPGGRFNEMYGWDSYFEALGLLVDGRLELAKGMVDNFVYEIQHYGKILNANRSYYLTRSQPPFLTDMMLKVYDRLPPSLEAENKHWLAGPLTAAIKEYLTVWLSEPRYDPESGLSRFYSEGIGMPPETEATHFDHVIKPFSDAKGMSINEYSKMYNEGTIIEPELDTYFKHDRAVRESGHDTTYRLDNHCADIGTVDLNALLYKYEIDIAETIHTIFGDSFETPFFESYETRSREKDGEKEERPKTVVHTSAEWFERARIRQEKIDRYCWNEERGMYFDYNTRLKTMDTYESVTTFYTMWAGCADRRKAEKMMSKALPLFEVKGGLVSGTESSRGFITLARPNRQWDFPFGWAPHQIISWIGFERYGFHEETRRTCYRWLYTITKSFVDFNGVVPEKFDVVNMTHKVQVEYGNVGVDFKFVPREGFGWMNASYQVGLGYMDRGLRRALGAVMDPNKVFQSELCKKTLDNQSFVEQPPDVTTRLFRPHRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUH9</accession>
    <name>A0A9P6MUH9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_011518</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000935">
        <property type="protein sequence ID" value="KAG0012780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUH9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="47"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0012780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="139" mass="14544" checksum="4CE5B765216D07D5" modified="2023-09-13" version="1">MSGQPMSGFPDLRSAGGIQMSPMSNSSTITNTGYNTNDHDYDRLLHGSSATSDSTSTAIGAAAIHNNHSNSHIGGSGGGTSSNGTGAPAHNSGLTRRVTLTGGSTGVSEVKLKRFLEHNKRLREQLEMHRVPVSEACHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUV3</accession>
    <name>A0A9P6MUV3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Pre-mRNA-splicing factor cwc22</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">CWC22</name>
        <name evidence="8" type="ORF">BGZ80_010446</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CWC22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000728">
        <property type="protein sequence ID" value="KAG0014421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUV3"/>
    <dbReference type="OrthoDB" id="1924287at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.180:FF:000004">
        <property type="entry name" value="pre-mRNA-splicing factor CWC22 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050781">
        <property type="entry name" value="CWC22_splicing_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003891">
        <property type="entry name" value="Initiation_fac_eIF4g_MI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003890">
        <property type="entry name" value="MIF4G-like_typ-3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18034">
        <property type="entry name" value="CELL CYCLE CONTROL PROTEIN CWF22-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18034:SF3">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR CWC22 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02847">
        <property type="entry name" value="MA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02854">
        <property type="entry name" value="MIF4G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00544">
        <property type="entry name" value="MA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00543">
        <property type="entry name" value="MIF4G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51366">
        <property type="entry name" value="MI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MI" evidence="7">
        <location>
            <begin position="383"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="340"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="580"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="10"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="340"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="591"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="631"/>
            <end position="645"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0014421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="645" mass="73109" checksum="B382C0F787FD6007" modified="2023-09-13" version="1">MEVQSVIVKPDAEEERRRPLADVDARRRAERERQMMEREPVVPKPRQNPEVEMKTLQATTRTGGAYIPPARLRMMQEQITDKSSKEYQRIAWEALKKSINGLINKVTASNIKAILPEMFGENLVRGRGLFCKSVMKAQAASMPFTPVYAAVVAVINTKLPQVGELLISRLIIQFRKAYKRNDKATCLATTTFIAHLTNQLVADEVLVLKVLALLLGQPTEDSIEIAVGLMKEVGSFLSQEASKANEGVFQSLRNILHQGKIEKRTQYMIEVLFQIRKDKYKDNPPIAPELDLVDSDEQITHMLGLDEDDLDAMEGLNVFKFDPEYLENEEKYSAIKAEILGEEDSDESGSDDSEDESDDEEESREALQKKMEIQDRTNTNLVNLRKTIYLTIKSSLNFEECCHKLLLIKLEPGQQIELCNMLIECCSQERTYEKFFGLVGERFSKINRDWSEAFQECFVTNYETIHRLETNPLRNVAKYFGHLMSTDAMSWGVLSAIHLNEEETTSSSRIFIKILFQDIVESLGLKKLDERVKDPRFSEWFAGLFPKDNPKNTRFAINFFTSIGLGALTTDLREHLKNAPKTIMAQNQDSSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSSASSSGSNRRRSSRSSRSRGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVH5</accession>
    <name>A0A9P6MVH5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">P-type ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ENA2_2</name>
        <name evidence="12" type="ORF">BGZ80_010703</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000775">
        <property type="protein sequence ID" value="KAG0014020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005391">
        <property type="term" value="F:P-type sodium:potassium-exchanging transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030007">
        <property type="term" value="P:intracellular potassium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006883">
        <property type="term" value="P:intracellular sodium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990573">
        <property type="term" value="P:potassium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902600">
        <property type="term" value="P:proton transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036376">
        <property type="term" value="P:sodium ion export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050510">
        <property type="entry name" value="Cation_transp_ATPase_P-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028031">
        <property type="entry name" value="DUF4460"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43294:SF21">
        <property type="entry name" value="CATION TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43294">
        <property type="entry name" value="SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14687">
        <property type="entry name" value="DUF4460"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08282">
        <property type="entry name" value="Hydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00121">
        <property type="entry name" value="NAKATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="751"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="920"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="951"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1487"/>
            <end position="1508"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1514"/>
            <end position="1534"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1555"/>
            <end position="1579"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1591"/>
            <end position="1611"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1623"/>
            <end position="1646"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1652"/>
            <end position="1676"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="11">
        <location>
            <begin position="676"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="374"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="424"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="58"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="374"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="393"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="430"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0014020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1691" mass="184940" checksum="2DA337EAF998E1BE" modified="2023-09-13" version="1">MRGHNVGKSGRNLRQNYVQQYLKQFLRRVHPDLFQNHPKEQLRNSTSLQDLLPLVNHEKDSHMDRRPPPSDSSVGSKPTKLVFYFKPNDPPIPPRLTLTDALKTTTHSQSQLESVEHILPMFEPKSISTETGDTARQSALEQELKSWQMVQSFLELCRKVGVSVKDSDQKDVALQLELSTQEITSKKSMNPQAPQKSLSEIFQEELQTSFSGSIGHQKPTPTWTGASTGNETNIEGISQTYLGKIGGVAPALDAQVMIKSNPLLFKSSELSSSRLSRVIRTWIHWQDEDQHLVTSSNTSIQSATPFRLGEWWRKVPIMILSSMKEREEVLSSPGNNQKGMLIVDQEMSKQEMIEYLKNNLERIQAEYKDMLKSTLMTPTSGGSPSALRKKQQEQQQVAQGHQPGWSPSPDAASYLERMRIKAQLQKARGGSRGRGGGGGDNSTSKRLPFDGDLGNDIAQDVPIALPSATPSNVEGYSIYSNIKDGKASIEHQIEINVVDLFDVKSNKDISLEEIMDGLRYVMEYRIKGGRYPNFEYDIMKRLADGLLLNMGHSEKKGRFRQTLSEEANVAFQLFGEFLLEVQEFRQAVGEKPVSDLRHALKLDVRCASGSTVQEQQAAVALIALLTNTYPQFSDWKELVKSSGQVDVQKCMREHAGYVKAEKMPEMPGVILAPQALCFDRKIKRCLKMFRTSLDTGLPSEAIPALQEHYGKNILPQPPRTSVFKMLWTQFTDFMILLLLAVAVLMAATKDFIPMTVLLIVVVLNAIIGFTQEYKAGKALDALTKLSVPKAQVLRDGATSVIDSEELVPGDIVILEEGESVPADLRLAEVSQLEIIESILTGESVAVNKDPREIKALTRKLPLGDCKGNAFMSTVVANGRGKGIVVRTGRQTEMGKISAAITGQGKILTPVQRKLAMLGKLLVVFAIVLCAVMAGVKIAYHPHEVGESLKVALSLAVSVIPEGLVAVVTVTMALGVRRMASRKAIVRTLPAVETLGSVTFICSDKTGTLTEGKMGAAELWTSDGSTYGFTESTSLDPNKGDVVLKTGSGEVTQVLEKTLNKVPAQMLISLMVSSLCNNSSVVAKGQEEESNSMEAITIDIVDDEKAHKAQLPASEWKGIGDPTEVALVVAAQKAGFPKSFFQDLGYTRIFEQAFDSERKVMSVVYKAPVDTFDTQGDHYEFVLAKGAPEEILNRCVGYLPPVEPNSISSPLDILKPSDCDLSKLVTEEFYDHVSEASGKMADSGLRVLGLAFKKVKVNGGGAVEKAIDDGLDSISNIKDSKEAAPPTHKPTDVDLMTAANVAAHGDDDDDDEIPPGYAESELIFLGLIGLIDPARAGVKESVRICKQAGITVVMITGDHIKTASAIAKELGILEEGGRAIKGEELDLLSEQAIAELRPFPNVFARVSPDNKLKLVTALQSRGDSVAMTGDGVNDAPAIKAANVGVAMGIAGTDITKQAADIVLANDDFNTIVEAVEEGRRVFDNILKFIVYLLSCNCAEIFLFLLCTFVDVPLPFTVTMILWANIIADVPPAMALGVEPAEPGLMSRDPRSPKRGILTVASFLVIIFQSFSMMLMTFGVYMWADRSEEHLDYAHSEAFAFLTTLQLLQGFLSRTMRTSILKSGFFGNVWMIYGVLISFVLMIIGIYTPGFNDILNLVPVGGVSWAKVVVGCIILTGLSELEKLILRRGGWTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVU7</accession>
    <name>A0A9P6MVU7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Alpha 1,4-glycosyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BGZ80_010332</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyltransferase 31 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyltransferase 32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000707">
        <property type="protein sequence ID" value="KAG0014634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVU7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007652">
        <property type="entry name" value="A1-4-GlycosylTfrase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002659">
        <property type="entry name" value="Glyco_trans_31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007577">
        <property type="entry name" value="GlycoTrfase_DXD_sugar-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044789">
        <property type="entry name" value="Put_A1-4-GlycosylTfrase_plant"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46781">
        <property type="entry name" value="ALPHA 1,4-GLYCOSYLTRANSFERASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46781:SF5">
        <property type="entry name" value="ALPHA 1,4-GLYCOSYLTRANSFERASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01762">
        <property type="entry name" value="Galactosyl_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04572">
        <property type="entry name" value="Gb3_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04488">
        <property type="entry name" value="Gly_transf_sug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Alpha 1,4-glycosyltransferase" evidence="11">
        <location>
            <begin position="609"/>
            <end position="698"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF04572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0014634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="879" mass="99357" checksum="733B4BE3E0F5B56A" modified="2023-09-13" version="1">MAICVIQAVALAIQTFHFKFRGMYRIDSPQSIWSLDPRAVILRRLLIPGGIVSFITMMMLLHQNNSYPSSAESLASTGAITIASLNAGKQIIGSAQTQVLIMILTSWTPKGFHKRQVVRETTLRLLPPPSAQFSFTYKFIIGEAPNARARETMGPKIKAEQETHDDLLILPVSDTYEDLSYKVFKALEWSNKFKFDFLCKTDDDIFVRWDTVIRELVDLGSTHYYWRGLAYWDIMPITNPENKNIDNQFKLGVFPPFVAGSLYIFSRDVVTLLTYPGPRFFTKNEDQNIGIWLHSYNIKPIHDMRIQQWDVCENDMIAKHFSDAFTPLESMHDMYKNIIESRPACQGFRQVYCAACYSCLGRSNHWRDWGVACDSVKGITSLNKHGLYQGKTSVDIKDPMPALSKKDEWILPGLLTDASSIYSDTDDWAKLHWAIWTTDPVTTWQSRHFQAIETLFVHNPNAVLIILSNTLPSDFFVNYTNQGYQIHILSFSKDLLLKRKWYFSPNTEDWLQRWDEWAEAGKFFPVHLADYLRLVALYKYGGLYMDMDALWVRAPGDGMTEFIGSDVSDTDSDRAWTLDAKNTYLANGVMRFQRGRSMFRHIAESYFTVTNYDPECFNCGGPKAFTTYVKAHRAALENNGLSILPREALYPYNWKEVEAAIRSSKNAKEEIRKVEQHGIGLHLYGKVTSRKTIEEGSVVATAIKIWGLELFPKSSLPLPTLQGPDTLYYDFTALSSSSPSTPLLSLSALIVASKGLLIGKIPGAFQGIDAVFMRGVPRHSSSSSNTLITEKAAITITVRDGLIAMDATGAGARSVEMSLGDSVTMAQLNTALSRMQYLPPIFSTPNHSWDSSDQVTIKVWFGEIHRELVIPVVLSMVKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWD2</accession>
    <name>A0A9P6MWD2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Organic hydroperoxide resistance protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_010103</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the OsmC/Ohr family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000669">
        <property type="protein sequence ID" value="KAG0015005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWD2"/>
    <dbReference type="OrthoDB" id="60422at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019953">
        <property type="entry name" value="OHR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003718">
        <property type="entry name" value="OsmC/Ohr_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036102">
        <property type="entry name" value="OsmC/Ohrsf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03561">
        <property type="entry name" value="organ_hyd_perox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33797">
        <property type="entry name" value="ORGANIC HYDROPEROXIDE RESISTANCE PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33797:SF2">
        <property type="entry name" value="ORGANIC HYDROPEROXIDE RESISTANCE PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02566">
        <property type="entry name" value="OsmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82784">
        <property type="entry name" value="OsmC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0015005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="167" mass="17461" checksum="7AA166AD8343E91A" modified="2023-09-13" version="1">MSLLRTAIRPAARLRLSAAPVTIAVRQLSFKPIYTSESTVKGARNGHLTTKSGSLDLNLNMPKEFGTAGGPGTNPEELFGGGYAACFGGALVVAAKELKLNLGSETTITSLVSIGPKPKGFQLAVELRVANSGLEGENFNKAVDLAHEICPFSHAVKGNIEVKTVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWN7</accession>
    <name>A0A9P6MWN7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_009224</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000532">
        <property type="protein sequence ID" value="KAG0016457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWN7"/>
    <dbReference type="OrthoDB" id="10265969at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000118">
        <property type="term" value="C:histone deacetylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1160.11">
        <property type="entry name" value="Paired amphipathic helix"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003822">
        <property type="entry name" value="PAH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036600">
        <property type="entry name" value="PAH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039774">
        <property type="entry name" value="Sin3-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12346:SF33">
        <property type="entry name" value="HISTONE DEACETYLASE INTERACTING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12346">
        <property type="entry name" value="SIN3B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02671">
        <property type="entry name" value="PAH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47762">
        <property type="entry name" value="PAH2 domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51477">
        <property type="entry name" value="PAH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0016457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="354" mass="40195" checksum="9183D5B782CBB297" modified="2023-09-13" version="1">MALTSDSQNNDSVMMDASNVNHSDQHQQPESRMAVAELLVSLSHSSRGDEQPDLTALATNIPETTGEPSQPSPIYKNAVDYVCSVKKAYESHPRVYTEFLSALEKYHGMSLPLDQLVQTVMTLFQDQPELLMGFKEFLPESQGLLNQLVPPMMYSDYKDRTPKAPTQAASQTTIPSTMLGVSSVEHNNTDSPGIAAADFLSIIKERSQQEPDMYQHMINLLRKFQKDNSYSTLYFYISIVLRYHPHLLQRFQNFLPKVPSNLEVKEPKIISKAPPEELVVSPDFIEAKDFIQTVKFEAKNEMSMYDRFISALEKYQLTGWTIDQVYSEVSLIFWNHPDALAGFKRFIATVPQQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWS4</accession>
    <name>A0A9P6MWS4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">T-complex protein 1 subunit zeta</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">CCT-zeta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">CCT6</name>
        <name evidence="12" type="ORF">BGZ80_008987</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Molecular chaperone; assists the folding of proteins upon ATP hydrolysis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the T-complex protein 1 (TCP1) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000508">
        <property type="protein sequence ID" value="KAG0016719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWS4"/>
    <dbReference type="OrthoDB" id="10052040at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005832">
        <property type="term" value="C:chaperonin-containing T-complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03342">
        <property type="entry name" value="TCP1_zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.560.10:FF:000038">
        <property type="entry name" value="Chaperonin containing TCP1 subunit 6B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.260.10:FF:000029">
        <property type="entry name" value="Chaperonin containing TCP1 subunit 6B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.560.10:FF:000058">
        <property type="entry name" value="T-complex protein 1 subunit zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.260.10:FF:000017">
        <property type="entry name" value="T-complex protein 1 subunit zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000004">
        <property type="entry name" value="T-complex protein 1 subunit zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012722">
        <property type="entry name" value="Chap_CCT_zeta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002194">
        <property type="entry name" value="Chaperonin_TCP-1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02347">
        <property type="entry name" value="chap_CCT_zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00750">
        <property type="entry name" value="TCP1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00751">
        <property type="entry name" value="TCP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00995">
        <property type="entry name" value="TCP1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 11" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00039582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0016719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="539" mass="59018" checksum="6054FD5E851E2EFD" modified="2023-09-13" version="1">MLSGGSAVSLINPNSEVARRGQALQLNINGAVGLMEVVRSNLGPKGTIKMLVSGAGDIKLTKDGKVLLSEMQIQNPTAAMIARAATAQDEITGDGTTSIVMLVGEFMKQAERHISEGLHPRIITEGFELAKKESLNFLDTFAVKKEIDRELLISVARTSLRTKVHRALADTLTEAVVDAVLTIYRENEPIDLHMVEIMAMQHRSETDTRLVRGLVMDHGARHPDMPKKVKDAFILTLNVSLEYEKSEVNSGFFYSSAEQREKLVESERKFVDEKLKKIVELKKQVCGDSGKGFVIINQKGIDPLSLDVLAKNGILALRRAKRRNMERMQLICGGVAQNSVDDLSPDVLGWAGTIYEHTLGEEKFTFVEDVKDPSSATILIKGPNPHTIHQTKDAIRDGLRAVKNTLEDGLVVPGAGAFQVALHSHLLKFKDSVKGRVKAGITSFAEGVLVIPKTLASNGGFDPMDVIVTMQEEYAEGHIVGVDLQSGETLDPVAEGIWDNYRVVRNMIQNSSVIATNFLLVDEMMRAGRSSLKADNGME</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWZ3</accession>
    <name>A0A9P6MWZ3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Acyl-protein thioesterase 1</fullName>
            <ecNumber evidence="4">3.1.2.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Palmitoyl-protein hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BGZ80_009026</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Hydrolyzes fatty acids from S-acylated cysteine residues in proteins with a strong preference for palmitoylated G-alpha proteins over other acyl substrates. Mediates the deacylation of G-alpha proteins such as GPA1 in vivo, but has weak or no activity toward palmitoylated Ras proteins. Has weak lysophospholipase activity in vitro; however such activity may not exist in vivo.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>S-hexadecanoyl-L-cysteinyl-[protein] + H2O = L-cysteinyl-[protein] + hexadecanoate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19233"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:7896"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="3.1.2.22"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.22" evidence="4"/>
    <dbReference type="EMBL" id="JAAAID010000511">
        <property type="protein sequence ID" value="KAG0016692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWZ3"/>
    <dbReference type="OrthoDB" id="2418081at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008474">
        <property type="term" value="F:palmitoyl-(protein) hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000276">
        <property type="entry name" value="Acyl-protein thioesterase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050565">
        <property type="entry name" value="LYPA1-2/EST-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003140">
        <property type="entry name" value="PLipase/COase/thioEstase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10655:SF17">
        <property type="entry name" value="LYSOPHOSPHOLIPASE-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10655">
        <property type="entry name" value="LYSOPHOSPHOLIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02230">
        <property type="entry name" value="Abhydrolase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0719">Serine esterase</keyword>
    <feature type="domain" description="Phospholipase/carboxylesterase/thioesterase" evidence="15">
        <location>
            <begin position="10"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00029392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00031195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0016692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="231" mass="25713" checksum="C59A5D954D6C18B1" modified="2023-09-13" version="1">MSATLKKLTSVIQAASSNHSATVIFIHGLGDSGAGWAPVGQELGRYLPHVKFIFPNAPDMPVTLNYGMQMPSWYDIKSLGNIDQEQDEAGMLKSRQQLMQIVREEIDEHGIPANRIVIGGFSQGCVMGLLTGLTSEYKFAGIVSLSGYMPLHNKIMSMASDSNRKTPIFWGHGDVDQVVRYQFGERSVEMLKQNKYNVKFNTYRNMGHSSCPQEIRDLLGFLKETIPPISQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MX81</accession>
    <name>A0A9P6MX81_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glycosyltransferase family 49 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_009322</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000547">
        <property type="protein sequence ID" value="KAG0016275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MX81"/>
    <dbReference type="OrthoDB" id="411524at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015020">
        <property type="term" value="F:glucuronosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042285">
        <property type="term" value="F:xylosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035269">
        <property type="term" value="P:protein O-linked glycosylation via mannose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051292">
        <property type="entry name" value="Xyl/GlcA_transferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12270:SF52">
        <property type="entry name" value="GLYCOSYLTRANSFERASE-LIKE PROTEIN GNT13-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12270">
        <property type="entry name" value="GLYCOSYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13896">
        <property type="entry name" value="Glyco_transf_49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0016275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="343" mass="39624" checksum="4B6295B4BE1C6A70" modified="2023-09-13" version="1">MSAIDRILESSSNRYWETEPAIVHTIRPKKTFPSRDITMIAQFSISRLDRFEKARAVWEGPISVVIFLATNTDIVELRKYFERPGKLALYDSVTLTIVKPNYSSGTHERYPINHLRNIGIQTSSTDYIYVIDADFVPSSQLYSFAKTTLIPLFEKSKEPVAYVVPCLAIQVDYKGQYPNTIKELQPLMKSGVAYITDPRAGHGPTFTSLFMNPPIFGNTPTYEVCYESQWEPYYIVKRDWSHPYYDERFKNQGGDKQSHALLLNALGYKFLVLRDHFMYHMDHPKLKWTGKGLDQTGQKDYTYFADYAPALEKIFGSNYRWPRGCSRPLVQSFRHDLQGIGTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXM4</accession>
    <name>A0A9P6MXM4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Integrator complex subunit 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">INTS2_2</name>
        <name evidence="2" type="ORF">BGZ80_008756</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000486">
        <property type="protein sequence ID" value="KAG0016945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXM4"/>
    <dbReference type="OrthoDB" id="3363059at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032039">
        <property type="term" value="C:integrator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034472">
        <property type="term" value="P:snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029321">
        <property type="entry name" value="INTS2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28608">
        <property type="entry name" value="INTEGRATOR COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28608:SF1">
        <property type="entry name" value="INTEGRATOR COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14750">
        <property type="entry name" value="INTS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="343"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0016945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="599" mass="67345" checksum="66DC7522853794AD" modified="2023-09-13" version="1">MLMRKDQPLAALVALVATLTVSKYRDLDYRLIQRQVKEELQLEKQNAATSTPTSRTRLFETGTNEDRARSLRSLQDPAPMIAYIIANNPTEFSLTIESLLDAKGHFHNSKAILLRLCKLADHKIWGVRQQLIERKVFPNLAIELTIEHCHDEICFMNRILRGQPEWLTNGIDPVTKTSLTSIMEFVFSSLNDELTSEQPDNIAVNRLLRILSGMIGLMNLSLNAEQLEISLGVLEMTPLIPSTVDVKICLILMSAAQLLKYSQPRVERILHQMIRCQDSPQVLSLLIFFQQQQLLKIDDLASRSLSMSIVIPRGGLMELSALFSSLFSSEELSQCALNIGRPKSLESEPKSSTEISPPESPHQFSQEDSELRSIANLITGHLLQQDIFHKSSTDVQRWVMEQIQASTVPLDANMIHLLRAYTSAIARSNHITRIPEREIRASFSNPSEDPTPAKVLLVLYMLMNNDVCVANLGSSNMERVQEYNSTLLEYVQVRKVALYVQNFQDGVAFRAVQPMFLKLVNAQFPELFDVTTLLLEESISTSSSTKAHPGSTLGSTDMVTTNVDTNLCKDPVAFMEPHFHSIRQHLNSPDSAVKGKYMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXM7</accession>
    <name>A0A9P6MXM7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3</fullName>
            <ecNumber evidence="6">2.4.99.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="24" type="primary">STT3</name>
        <name evidence="24" type="ORF">BGZ80_008965</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="24" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="24">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="18">Catalytic subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. This subunit contains the active site and the acceptor peptide and donor lipid-linked oligosaccharide (LLO) binding pockets.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>a di-trans,poly-cis-dolichyl diphosphooligosaccharide + L-asparaginyl-[protein] = N(4)-(oligosaccharide-(1-&gt;4)-N-acetyl-beta-D-glucosaminyl-(1-&gt;4)-N-acetyl-beta-D-glucosaminyl)-L-asparaginyl-[protein] + a di-trans,poly-cis-dolichyl diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22980"/>
            <dbReference type="Rhea" id="RHEA-COMP:12804"/>
            <dbReference type="Rhea" id="RHEA-COMP:12805"/>
            <dbReference type="Rhea" id="RHEA-COMP:19506"/>
            <dbReference type="Rhea" id="RHEA-COMP:19509"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:50347"/>
            <dbReference type="ChEBI" id="CHEBI:57497"/>
            <dbReference type="ChEBI" id="CHEBI:57570"/>
            <dbReference type="ChEBI" id="CHEBI:132529"/>
            <dbReference type="EC" id="2.4.99.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the STT3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="24">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.99.18" evidence="6"/>
    <dbReference type="EMBL" id="JAAAID010000506">
        <property type="protein sequence ID" value="KAG0016738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXM7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008250">
        <property type="term" value="C:oligosaccharyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004579">
        <property type="term" value="F:dolichyl-diphosphooligosaccharide-protein glycotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043687">
        <property type="term" value="P:post-translational protein modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018279">
        <property type="term" value="P:protein N-linked glycosylation via asparagine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12610:FF:000001">
        <property type="entry name" value="Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003674">
        <property type="entry name" value="Oligo_trans_STT3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048999">
        <property type="entry name" value="STT3-PglB_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048307">
        <property type="entry name" value="STT3_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13872">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13872:SF1">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT STT3B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02516">
        <property type="entry name" value="STT3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21436">
        <property type="entry name" value="STT3-PglB_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="15" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="16" id="KW-0464">Manganese</keyword>
    <keyword evidence="14 21" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 24" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 21" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 21" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="110"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="136"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="165"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="187"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="231"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="263"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="297"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="355"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="381"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="Oligosaccharyl transferase STT3 N-terminal" evidence="22">
        <location>
            <begin position="13"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="domain" description="STT3/PglB/AglB core" evidence="23">
        <location>
            <begin position="556"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="441"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="442"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="24">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00048829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00059243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00067960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF02516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="Pfam" id="PF21436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="KAG0016738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="742" mass="83290" checksum="67556EE97464FB29" modified="2023-09-13" version="1" fragment="single">MSTESTSTVAKVLKPTILILIAIVAIASRLFSIIRFESVIHEFDPWFNYRTTQHLVKNGFYDFWNWFDEKSWYPLGRVVGGTVYPGIMVTSALIHNVLHFFNFPVDIRNVCVFLAPMFSGLTAFSAYLLTKELKDSSAGLLAAAFLGVAPGYISRSVAGSYDNEGIAIFLLVFTFYLWIKAVKTGSAFFGLMTALFYFYMVSAWGGYVFITNLVPLHAFTLVLMGRFSNRLYVSYSTFYAVGTLLSMQIPFVGFQPTRTSEHMAALGVFGLLQLYAFAELVRGYVSPKQFKTLLKGGIASVAIVSVVILTLLSLTGVVAPFTGRFYSLYDTGYAKIHIPIIASVSEHQPTAWTSFFFDLQMLIFLFPAGVYLCFKELKDEHVFIILYSVFASYFAGVMVRLMLTLTPVVCVSAAIAYSTLLDTYLEKSDHVLASSLRDAAAPSDTSDSKASGSSSKKPIPKGKTPETEPKPQPKSSATGEKKRFPIFNWDSRLVVILQLTWFLFMFAWHCTYVTSGSYSSPSIVLASRNQDGSQMIIDDFREAYYWLRKNTKEDAKVMSWWDYGYQMAGMANITTLVDNNTWNNTHIATVGKAMATSEEVAYPLLRRHDVDYILIIFGAVIGYSGDDINKFLWMIRIAEGVYPNEVKEANFFTSRGEYKVDHDATLTMKNSLMYKMSYYRFADLYGGNAVDHVRGARMPSEGPSLSVLEEAYSSEHFLVRIYKVKQPDNLGRNLKDATAFDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXT8</accession>
    <name>A0A9P6MXT8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_008767</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000488">
        <property type="protein sequence ID" value="KAG0016924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXT8"/>
    <dbReference type="OrthoDB" id="407410at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24347">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 3 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="22"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="284"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="313"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0016924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="382" mass="43228" checksum="3AA3B80448A6FB19" modified="2023-09-13" version="1">MGLEYTFNRGEKESNMTFDSQFEIGEQLGSGNFASVFKTIEKTSGMAYAVKVVKKSVNFNSKLALSLEREIGTLMSIDHPSLLQIYKVFSEENHHYVVTELARGGELFDRVREKRRFSESEARFVFRQLLNGVKYLHDRGIVHRDLKLENILLMDEDSLIVKISDFGLANVIGEQQFLNTICGTPNYDDLAPPKLRIQVLESRYTFPSPYWDDVTDEAVDMVQDLLVNDTEQRLDVDGALAHVWMNLKDDQGTIPEHSRTEIMPQVNALVKSLSSHHLYKLRERSRTRSLQSLRSEQSRRSHNSQKSLSSSSIDERAKDRELPQSSPRLPVEGGSDSAATILVSNSDNNGENSNDDKGPLNEGISQATHSAFAAHRPKYFTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYS8</accession>
    <name>A0A9P6MYS8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cofilin</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Actin-depolymerizing factor 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">COF1_1</name>
        <name evidence="7" type="ORF">BGZ80_007434</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the actin-binding proteins ADF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000380">
        <property type="protein sequence ID" value="KAG0018222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYS8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015629">
        <property type="term" value="C:actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016363">
        <property type="term" value="C:nuclear matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030042">
        <property type="term" value="P:actin filament depolymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11286">
        <property type="entry name" value="ADF_cofilin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002108">
        <property type="entry name" value="ADF-H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017904">
        <property type="entry name" value="ADF/Cofilin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11913">
        <property type="entry name" value="COFILIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00241">
        <property type="entry name" value="Cofilin_ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00102">
        <property type="entry name" value="ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55753">
        <property type="entry name" value="Actin depolymerizing proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51263">
        <property type="entry name" value="ADF_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ADF-H" evidence="6">
        <location>
            <begin position="4"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00032427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0018222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="138" mass="15672" checksum="33B5FDB9672712C8" modified="2023-09-13" version="1">MNSASGVQADPDCVASFQELKLGKKVKFIIFKLSDDNKSIIVERKAETATYDEFLKHLPKNDCRWAVYDFDYKTPEGDRNKIVFYTWLPDAAPIKSKEWYTVNKDALFRSLDGIGAEIQDTNYDGVSYSTVLKSVARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYY6</accession>
    <name>A0A9P6MYY6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">SAGA-associated factor 11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BGZ80_008134</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the SGF11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000432">
        <property type="protein sequence ID" value="KAG0017591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYY6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071819">
        <property type="term" value="C:DUBm complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013246">
        <property type="entry name" value="SAGA_su_Sgf11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051078">
        <property type="entry name" value="SGF11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46367">
        <property type="entry name" value="ATAXIN-7-LIKE PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46367:SF1">
        <property type="entry name" value="ATAXIN-7-LIKE PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08209">
        <property type="entry name" value="Sgf11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0010">Activator</keyword>
    <keyword evidence="5" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="123"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="269"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="123"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="146"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="167"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="192"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="222"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="273"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="291"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="403"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU261113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0017591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="430" mass="45615" checksum="FE0C99B6F619D183" modified="2023-09-13" version="1" fragment="single">LLRHTKRAMDRSMASRDGSDIGGISMASLSFEILGELLDEVILDVVAESHRDVKNMRSNCPVCKTKCRNYVSRAGVDIFGQNPQANNSQTYDCVHCQRSFPAQRYAPHLEKCLGLSGRSSSRAASRRMGAGERAGSGSPFTPVSYSDDREASDSDKDLIEKKRKKNASSSNGFLANANGSNGSNGGDEYIASSSTKSSSSGSVKSKKQKQVDSSEYPAKIQKSSLLAKASKGGGSSKLKGLGLHSPSVAPVGEISLEYFDNDVLLANGRSLQNGAGSSNAGSTSGTNTSTPQKLSSSNPKRTSGGISSSKRPPGSGLSSSKNGQVISFHERLKAIGSRDGSSSSSSDEDEGDKNSRDEDYRDYEEEGRRGEGGSTHSSSQHIHPVAFRHKKSSAYSGHASDSIDSEFIDIDGDGDDDAMEILQTPKKKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZ02</accession>
    <name>A0A9P6MZ02_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Cysteine synthase 1</fullName>
            <ecNumber evidence="4">2.5.1.47</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">O-acetylserine (thiol)-lyase 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15">O-acetylserine sulfhydrylase 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="16">O-succinylserine sulfhydrylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BGZ80_006188</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the conversion of O-succinyl-L-serine into cysteine, the last step in the cysteine biosynthesis pathway. Can also use O-acetyl-L-serine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>O-acetyl-L-serine + hydrogen sulfide = L-cysteine + acetate</text>
            <dbReference type="Rhea" id="RHEA:14829"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:58340"/>
            <dbReference type="EC" id="2.5.1.47"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>O-succinyl-L-serine + hydrogen sulfide = L-cysteine + succinate</text>
            <dbReference type="Rhea" id="RHEA:53816"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:136856"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-cysteine biosynthesis; L-cysteine from L-serine: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.47" evidence="4"/>
    <dbReference type="EMBL" id="JAAAID010000304">
        <property type="protein sequence ID" value="KAG0019193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZ02"/>
    <dbReference type="OrthoDB" id="10259545at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004124">
        <property type="term" value="F:cysteine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01561">
        <property type="entry name" value="CBS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000011">
        <property type="entry name" value="Cysteine synthase (o-acetylserine)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050214">
        <property type="entry name" value="Cys_Synth/Cystath_Beta-Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001216">
        <property type="entry name" value="P-phosphate_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007989">
        <property type="entry name" value="PRK10717.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10314">
        <property type="entry name" value="CYSTATHIONINE BETA-SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00901">
        <property type="entry name" value="CYS_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Tryptophan synthase beta chain-like PALP" evidence="17">
        <location>
            <begin position="33"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00050981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00058228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00072087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00078262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00079147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00081847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAG0019193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="364" mass="39175" checksum="B602DB263D9387D9" modified="2023-09-13" version="1">MIKTGISSVSKRGFATFKPVISAAKPVEGFVGALGNTPLIRLNKLSEETGSNIYAKAEFMNPGGSVKDRAALYVVKDAEEQGLIKPGGTVVEGTAGNTGIGLAHVCRAKGYKCVIYMPNTQSQEKIDLLRMLGAEVYPVPAVAFDNPENYNHKAARHAKSIDNAVWTNQFDNTANRQAHIETTGPEIWSQLDGKVDGFTCATGTGGTLAGITRFLKEKSGGKTKVFLADPPGSVLYSYIKSGGKLNDRSGSSITEGIGQGRVTDNLKPDIELIDDALQIRDEDSLHMIYRLLDEEGIYVGASSALNVVAAVEMAKKLGPGKNIVTILCDGAYRYQSRLFSKKWIESKGLTNAIPEHLKKYATLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-10-08" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZQ5</accession>
    <name>A0A9P6MZQ5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Arm-like repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_006045</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000299">
        <property type="protein sequence ID" value="KAG0019265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.80">
        <property type="entry name" value="E3 ubiquitin-protein ligase SopA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056251">
        <property type="entry name" value="Arm_rpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053299">
        <property type="entry name" value="ASTRA_WD_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44156">
        <property type="entry name" value="SUPERNUMERARY LIMBS, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23948">
        <property type="entry name" value="ARM_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="16"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141571">
        <property type="entry name" value="Pentapeptide repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="15"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Arm-like repeat" evidence="4">
        <location>
            <begin position="72"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1092"/>
            <end position="1133"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1134"/>
            <end position="1175"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1176"/>
            <end position="1217"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1218"/>
            <end position="1259"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1260"/>
            <end position="1301"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1302"/>
            <end position="1343"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1344"/>
            <end position="1385"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1386"/>
            <end position="1427"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1427"/>
            <end position="1468"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1469"/>
            <end position="1510"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1511"/>
            <end position="1552"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1553"/>
            <end position="1594"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1609"/>
            <end position="1640"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1641"/>
            <end position="1682"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1683"/>
            <end position="1726"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF23948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0019265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1772" mass="196078" checksum="3290B4C2DC5C5500" modified="2023-09-13" version="1">MQQVNLGSNAMLQPTKDVVQAPQRIFDQDIVLPAVNYALPVAASNISSTPQLAYCLSLLRSSSVSEVELDWLQTKVSDLDEQNRFKTLSTDLIRAFVRDELKKAEVVAEVVCLAAVLDQDDFSALLKAFVNGIEQSVLLKVHLIDGLAQLVRNAAPGYIDTDDLVKVLELLDTRLNETHEQSTEHIYRLTSALSRVLDSMVDAQVKGLKREQLHEPLSAYLKKLQDSSDPSLVYQAAYGYQALQYIPDDETILQARVRRTRKIISGISGVVSAVKAIDLNHFIEGLQSIQGGLAGANSAIGLLYDAYDNAKALAESGQGLLQSLKEGFSFSRKSAWYPALRGLDILLQEGKLVEFEKLIREAPCRKDVAFHWGVCQRLGEIAFSPLWGANARQRAIAFLEELYKDESVWGQQAHIKLLILQILTQLADSSDNVASQARKLLGELETNVDTVEQALPQDSPKEYSEYSSRYPFMVSLAPQTSPLLACVQNKSDLETPLRKLKRDRTNGRSKDVYISPRAKANLRATEDFDLNSKVQEFLESNKKVFLLLGDSGAGKSTFNRTLEIHLWDKYENVDGRIPVFVHLPTIDKPEYDLIAKQLRRANFTEEQIQELKASREFILICDGYDESQQTRNLYTSNQLNQTGGWRARMIISCRTEYIGVDYKESFQPTDKDHGSLPELFQEAVITPFNKDQIRDYINQYITLCKPSWEPEDYQRALKEIPNLQDLVKNPFLLKLALEVLPQLVDRASDFSLARVTRVGLYDEFVAQWLERGKVRLMDVELSPDDKEAFKTLSASGFKQHGTTYLKELTTAIYDNQNGKPVFSYVEPGDLRTWKEAFFGREDGKNLLLEAMPLICSGNQYWFIHRSVLEYGLTLAVFDPSEQGERDDEPTLSVSRRGSAASILSFEAPSLAEDSADSADSARQALLDSPLGRRNFVKERSILQFLVERVQQQPGFKVQLHAVIEESKTDKKWRIAAANAITLLVKAGVQFNQADLRDINIPGADISNGVFDSAQLQGSDLRKVNLQNAWLRQADLSGAQLSGVLFGELPYLKENSSIESCAYSPDGSKFAVGLADGDISLYETLNWSKVGELKGHTKDVCCLAFSVTSDRLASGSNDMTVRLWDTDTFNCIHTFEGHRSNVASVAYSPKGDQLASGSDDKTLKLWNVENGNCIHTLLGHIGEVVTVQYSPDGDQVVSGSKDKLVKLWDVGTGNCIQSLKGHSGAIARVLYSPKGDHFISASLDCTLRLWDAGTGGCVHILRGHGSSVISVAYSPKGNQIASGSWDNTVRMWDIETGACVHTLEGHSDWVHTVAYSSKGDRIASGSDDFTVRLWDVESGSCIQTLQGQNLKVTSVLYSPDGNQIASGSSDKTVRLWDVKTINYVQTPHGHDNCVVSVRYSPNGCQIASGSDDCTVRLWDVETGNCVKTLEHSQRVASIAYSPKGNELVSGSWDWKVRLWDVETGNCAHILQGHGDSVRCVLYSPRGDQVASGSDDSTVRLWDVETGECIHILEGHEGYVNCIAYSPNGDQIASASDDYTVMLWDVKTGEWLRSFEGHDKEVTSVYFSPAGSHIASASWDRAVRLWNVETAECVHTLEAQGEDVSKELSVIAYSPKGNQVASASEDGTVRLWDVDTGDCIHALEGHEGSMVCIEYSPLGDRIASGGYDGTLRLWSVETGECLVVISGFNGAVVCVAWEDTSHGQYLLTGSEDKSVRRWQITKEQDEYRALLSWSSSHDGLTAAGATFHDLNDLGEVNRALLCQRGALITPSSAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZV8</accession>
    <name>A0A9P6MZV8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_006985</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000350">
        <property type="protein sequence ID" value="KAG0018603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZV8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0018603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="548" mass="62014" checksum="719A631EF6123A0C" modified="2023-09-13" version="1">MMTQSPLDLSEIRYMIGFFLSSTDLISCTQVSRNWKASFEPLIWRSLWLCRRPLRRDDTLVLPSISAVEQNAYHVQHLTMSTNLCPAILPYLTVNFQHLRSIKVVCHNLKPSKSSTTVKINVNNNRYNYTKEQEEYEMLLWGVIPTLLRENPALNEVEIGSTSICSMPSSTLWNEHADSFFGNLGQRVTDSTKTLVGNSFNKKPLTLQRTAIGEMEIPTHYSTTTSPCFIKTLELFKLNALSRSTQLNVIRQCPFLQSLHWFPCHIENGADESESPLSIAVSFTASVRSKVWSHLNLLDAEWLCLSDEQWSCFLESISQGDLKQVYAKRSGFGKQAFASLMNLHKSSIRTLDLEACPGVTSRMLILVLRNCTYLEDLGADAIKVSDIEQLQEMEVKDTQGLWASAAPSKWACIGLKSLRVEFDMAPKSTFSPATVHASPECLNSQSSLLPPGSLSLQPSPCLTQNLRSQHYNQVVFRQISTLKQLETLYIREGIICSTRLQLRYCFEALHQLPELKHLVLGRDMQCFGKENIKEMLKAARSFQGLEEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0U8</accession>
    <name>A0A9P6N0U8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005417</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000267">
        <property type="protein sequence ID" value="KAG0019689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0U8"/>
    <dbReference type="OrthoDB" id="2434756at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12824">
        <property type="entry name" value="MRP-L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="37"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0019689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="273" mass="29354" checksum="BD50BBA8FB43DC71" modified="2023-09-13" version="1">MGSSASKTTSGAKSAARHFPSANVIHERAANATAAAAAASKATASKTAAASSSPKQDYLEEQKRLEEELSRYDEQLKKSGKFDGESRPLEDTPSAAELQFFGNLRSIGQVKVPNPDQIKHQEAAEILKHKLPAKPISSSSNTVPFAQSSPFPPTTSNSSETGANLTSLKLMQLLQLRNQDPSVWTLDQLSEEFSMKKEDIQAVTKYINTYTILPGKDAKGRESGVWCEDLRGVEILERPSSVLKDGSEADETKSKSPSGGAARSGSENKARTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1L4</accession>
    <name>A0A9P6N1L4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Serine/threonine-protein kinase TOR</fullName>
            <ecNumber evidence="11">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">TOR1_1</name>
        <name evidence="15" type="ORF">BGZ80_002779</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the PI3/PI4-kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="11"/>
    <dbReference type="EMBL" id="JAAAID010000170">
        <property type="protein sequence ID" value="KAG0021249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031931">
        <property type="term" value="C:TORC1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031932">
        <property type="term" value="C:TORC2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044877">
        <property type="term" value="F:protein-containing complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016242">
        <property type="term" value="P:negative regulation of macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038202">
        <property type="term" value="P:TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05169">
        <property type="entry name" value="PIKKc_TOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1070.11:FF:000029">
        <property type="entry name" value="Serine/threonine-protein kinase TOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.150:FF:000001">
        <property type="entry name" value="Serine/threonine-protein kinase TOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000371">
        <property type="entry name" value="Serine/threonine-protein kinase TOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1010.10:FF:000006">
        <property type="entry name" value="Serine/threonine-protein kinase TOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.150">
        <property type="entry name" value="FKBP12-rapamycin binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1010.10">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050517">
        <property type="entry name" value="DDR_Repair_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003152">
        <property type="entry name" value="FATC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009076">
        <property type="entry name" value="FRB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036738">
        <property type="entry name" value="FRB_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057564">
        <property type="entry name" value="HEAT_ATR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024585">
        <property type="entry name" value="mTOR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018936">
        <property type="entry name" value="PI3/4_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003151">
        <property type="entry name" value="PIK-rel_kinase_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014009">
        <property type="entry name" value="PIK_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026683">
        <property type="entry name" value="TOR_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139">
        <property type="entry name" value="ATAXIA TELANGIECTASIA MUTATED ATM -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139:SF9">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE MTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02259">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02260">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08771">
        <property type="entry name" value="FRB_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23593">
        <property type="entry name" value="HEAT_ATR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13513">
        <property type="entry name" value="HEAT_EZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11865">
        <property type="entry name" value="mTOR_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01346">
        <property type="entry name" value="DUF3385"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01343">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01345">
        <property type="entry name" value="Rapamycin_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47212">
        <property type="entry name" value="FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51189">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51190">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00915">
        <property type="entry name" value="PI3_4_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00916">
        <property type="entry name" value="PI3_4_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6 11 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 11" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FAT" evidence="13">
        <location>
            <begin position="1247"/>
            <end position="1799"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="12">
        <location>
            <begin position="1974"/>
            <end position="2295"/>
        </location>
    </feature>
    <feature type="domain" description="FATC" evidence="14">
        <location>
            <begin position="2335"/>
            <end position="2380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU364109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0021249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="2800" mass="318319" checksum="CD6B22ABF821FF91" modified="2023-09-13" version="1">MATATPPTLSRLTSDLKASLQNEKARNLNTLKLKEYVTLTSRELSGEDLTKFYGEVNSTIRTLVQSVDNDDKLCGALIIDTLIGVEDEDNTAQETRFANYLRQLFPSDVPTMTVAARALGKLAQQRGPFTADFVEFELTRAIEWMAGDRQEARRHASVLVLAELARHANVIVYPHVGTILNNIWGAMREPKQAIREAAADTLSAVLVLIADRVTSQNQQTVSWYNRIHDEAQRGLRIASTESIHGSLLIFRELALHANMYIYEKFRDTCDTVLRLKDHRDSLIRRTVMHLLPVLAAYDPSDFMVFYMDRSMSHLLGQIQMDKEWKAATDADRSIAFQAIGKLALVAKRDMEEYLSEAIHCIKEGLRAKNKPRIASSESIFGCISMLAQAVGQSMGFYLPELLDLMLATGLSEAMCQSLTDLSIYIPHSLSGIQERLLNTISLILSGSVYRDPGAPKPKKTVLTKSSSYYQEARNPETIMLALKTLGSFNFSEHRLNEFVRDSCIIYLDDENAGIRRAAAQTCCQLFARDPIVFQTSTHAVQVVGEVLEKLLLVGIADPESSIRRTILTSLDERFDHHLAKAENVRSLFIALNDEKFDIRELAITILGRITKFNPAYVIPHLRKILIQLLTEIEYSGLTRNKEESARLLTLLVMASQTLVKPYIETVLKVLLPNIRDSSPGIVSSVLEALGEIAQVGGEDLLPYMDQLMPMFIEVLQDQSSPVKRSAALTSLGRLASNTGYVIDPYLKYPVLLDILMSILKTEQSVRIRQETIKLVGVLGALDPYRHKQMVMKSGDQNQADKAENADVALLMSGMEPSSDEYYPSVVIGALLKILKDPSLGQQYQPATQAILNIFRSLQLKVVGFLPQIMPVYLTIMQSGTVQNLDFYFEKMGVLVQIVTLHIRPYIPDLLKLIEDNWSRTRLQERVVGLIESVAISLDGEYKSYMPKLLRSMLAVLDSDISEKRGASHRVLQAFVRLGSNVEEFMHLIIPALVKTFEKTDAPMNLRRAAISTVGALSRRIDFSDYASRIVLPLVRNLTSPGQELRNVTMDVLCLLVVQLKQDYVGFVPLVRKIVIRERINHPNYNLVVTKLINREPLPSASELTGLGDDRYVVATDVPQALSDSRKLPVNPIALRRAWDTTSRSTKEDWTDWIRRLTLEMLKETPSHSLRACADMANSFPPLARELFNCAFMSCWMSLTEQFQDEFAEAIKTALVAKNISPEITQTLLNLAEYMEHDDKPLPIETSTLGKYARGCHAYAKALHYNELQFMKDHSTSIIESLIGINNHLQQSDAAAGMLTYAQRHHDIELKESWYERLHRWEDALAAYERKQIENPNDLLLTLGRMRCLHALGEWSPLSKLGQEKWSLAPPDFRRGMAPFVAAAAWGLGQWELLDDYVSVMQEESPDRAFFKAVLSLHRNEFAMAEKLIEHTRTLLDTELTALVSESYSRAYNTVVRVQMMAELEEIISYKRYEGQPDRQATIRKTWMKRLLGCERNLEIWQKVIKVHAMALTPSEDMDLRIKFTNLCRKSGRLRLADKALIALMGRETAEMSFTQMIQVTPPQVVYAKLKCMWAAGIREQTLECLRQFTDRLASDLGLGTIGSNGTALTGVNRTHGSEEDFSRLLARCYLKQGEWQFAMQDGWTAESIEYILLPYSNAKNLDKNWYKAWHTWALANFNVISFYERNGASGATQGLPYVIPSVKGFFRSIALSAGNSLQDTLRLLTLWFKFGHRADVSAALAKDFPTVNIDTWLQVIPQLIARIHAPSQNVHRLIHQLLADVGKAHPQALVYSLTVASKSPSVFRKDAALAIMEKMRLHSPVLVDQASLVSQELLRVAILWHEMWQDGLEEALTLNSQGGRSNIDTILDVLEPLHQMILKRPETHHEASFAKAFGRDLEEAFKCCTRFRQKQDIGELNQAWDIYLQVYNRIKKLPFLSTLELPYVSPQLQNARDLELAIPGTYRSGEPVIRISSFNHVLTVLNTKQKPRKLTVNGSDGREYAFLLKGHEDLRQDERVMQLFGLVNTLLATDPETFKRHLNIIQYSVIPLSPNSGLIGWLPETDTLHNLIREYRESRKLSFYIEHQLLTQMAPPSEGSKGYDSLTVMQKVEVFENMLNNTKGDDLYKILWLKSRNSEVWFERRTNFTRSLAVMSMAGHILGLGDRHPSNMMMDRNTGRIVHIDFGDCFEVAMHRPQFPERIPFRLTRMLVQAMEVSGIEGSFRNTSENVMRVLRENKESLMAVLEAFVHDPLINWRILNTSPRQQTNAPQARNGTINESFIADQARSLRRPLPSEQQLVSDNVEVNAQPEQQLNQRAVTILTRVTNKLTGRDFHPDVTLDVPSQVEKLIRQATSTENLCQCWFGGEEHCPSKPPHQASVPWKLPLESQLISSVTSLSSLTTLKLKDSLVVHRNDYRAQLQRLPEALQTFELAWWIENNTEVKEIGHFPDVGWRDAYTRLRDLSLAAHRDATLSLFLRRCPALKLGIVQEEEVIIEELCPLLADTRIFPRLTSIDIREYVIEGYELIDWRRLGSAMRSRVTAISIDTFNLLDIGNLCDNWASTLETLRIGPYTVDMTSGSIELILTTCSRLKTLVIFSDVSPDDGYDDRNIGYWTWCDGVYNDSKDNWICLGLEHLELTFLDIRACSPDTIYHQQTNGCNSSQLELYTFNRIHKSFYQLGRLTKLRHLRLGWRSDAMFKHRANLDLSISSGLMHLAGLKELEILDVTCIAHVNIEEEEVEWMTENWPMLCIIKGYFKKVPRLHRLERDEDDLDEDIYSARREESDDPMPIEWLLSQRPHLEIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N225</accession>
    <name>A0A9P6N225_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">phosphatidate phosphatase</fullName>
            <ecNumber evidence="3">3.1.3.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_002898</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the lipin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.4" evidence="3"/>
    <dbReference type="EMBL" id="JAAAID010000174">
        <property type="protein sequence ID" value="KAG0021183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N225"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008195">
        <property type="term" value="F:phosphatidate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009062">
        <property type="term" value="P:fatty acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019432">
        <property type="term" value="P:triglyceride biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000063">
        <property type="entry name" value="Nuclear elongation and deformation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026058">
        <property type="entry name" value="LIPIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031703">
        <property type="entry name" value="Lipin_mid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007651">
        <property type="entry name" value="Lipin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013209">
        <property type="entry name" value="LNS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031315">
        <property type="entry name" value="LNS2/PITP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12181">
        <property type="entry name" value="LIPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12181:SF12">
        <property type="entry name" value="PHOSPHATIDATE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16876">
        <property type="entry name" value="Lipin_mid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04571">
        <property type="entry name" value="Lipin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08235">
        <property type="entry name" value="LNS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00775">
        <property type="entry name" value="LNS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LNS2/PITP" evidence="7">
        <location>
            <begin position="736"/>
            <end position="891"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="125"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="245"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="597"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="978"/>
            <end position="1035"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1056"/>
            <end position="1115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1154"/>
            <end position="1198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="137"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="270"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="284"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="356"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="372"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="398"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="597"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="624"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="651"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="993"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1059"/>
            <end position="1077"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1101"/>
            <end position="1113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1166"/>
            <end position="1191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0021183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1198" mass="131989" checksum="333825B122D09EE5" modified="2023-09-13" version="1">MQSVGSFFSSVTKFYSELNPATLSGAIDVVVVEQPNGELACSPFHVRFGKLSILRPQEKVVEVTINGHVVDFPMKVGDAGEAFFVFETEQEVPEEFATSPLAGPSESKAEEDIDFLDLAQEGDAGYVSAHSGHGSEFEEDEGEDEEGETSSPDVSIDLEDGRKRSATIRSRLSISVSLPCSPVLKAHDIMENFQPVDSAGPFGDSDDAQLDIREDQLSTSSSSGVISKSNVMRTHRDQVIMDMTGYKTDDSPDSDFDSDGPWKEASWASRRTRKKRGRAARLNFGTTAPTHVEQNQATAGDGTDSRLPLRPTSRPKDRNIPGHNLKRSPSLPNMREKGHIKTSFLQKPRNIGGDRSSFSSTTAVSLTSSRNSQHRHHNHHQHHRDDNSKSRPRRHSHKPTEQKNEQKPVPRPNLATNPLSDTELEYQTPRNAKDSEWSWGWGSLPVKNDDMEENEKHTDHVAIDPSSHPKPALNEMEVEGVTYRVAISLCPGDDFGKDLEASEVLFATNQISFDEFSKDPLKILNNKNLVCLINDRYFTWSTAGPYLASLMLFKKPLSDETLHQLSVKDGRDLSERSPVQQAPTRFSAISRWFRGSQPANQVDTSEQVQLPPSPTSDVASQAGHENEETYDKSTKLGNNLQRESIDKDPITRSTSLPIDTAKSSPIVSEDKQQAPPATDSKNTKRYAKTLRLTSEQLRSLNLKKGPNTLTFSVTSSYQGKAVCSAKLFLWDHDVQVVISDIDGTITKSDALGHIFTMAGKDWTHTGVAKLYTDIVNNGYHILYLTSRAIGQADYTRKYLKNVEQNNYQLPDGPVIMSPDRLMTAFHREVILRKPEEFKMACLRDIRRLFGDRNPFYAGFGNRITDALSYRSVGVASSHIFSIDPSGEVKLELLSTFKSSYLALNDLVHEIFPGDRNAPEFNDWNYWKPTLPTIDLPMAPSKHPTLPQSPVDYNTYSSGMSGGTGRLGVIRSLTSSFTSAGPLKKRPSIPAFNSSPSSTPTTSSLPGQTSPRSLTPLSTTASSSPLPPPASAPAGLQIADRTRRLSLSIMKYGSNAISLSPSVSPTSSSPETETPATVGDQRTRARGMSMTSGGYIPSNLGTSPPTSYSSLTSSAEPVHPLDVQTVKRESSFSVSPPQGQGPEFREELADELYVEEEGEYEGQLNDDGAEYEDEYGDENPEEDEDDDDDVELNIDAPFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N237</accession>
    <name>A0A9P6N237_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bromodomain-containing protein 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">BRD8</name>
        <name evidence="2" type="ORF">BGZ80_001198</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000127">
        <property type="protein sequence ID" value="KAG0022031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N237"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035267">
        <property type="term" value="C:NuA4 histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15398">
        <property type="entry name" value="BROMODOMAIN-CONTAINING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15398:SF4">
        <property type="entry name" value="BROMODOMAIN-CONTAINING PROTEIN 8 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="188"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="225"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="294"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="321"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="366"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="395"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="405"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="439"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="462"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="493"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0022031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="515" mass="56277" checksum="720AEA539131115B" modified="2023-09-13" version="1" fragment="single">MSDPTATDIKSDSEPWSVLENLILVQAIYKCGDTNWVAIARTIKGHPQVHRSSNFFSQRSCAIQYTQLLENLEAETRSKHSRGNEAGTSATQEIPSVVKLAGQLYNQRILEIKALIRKDEERFRALVAELDEIRQGKWDSQLAEELKNNPVEADSEVTTNGVIDNSSSTDASQLQPEGENALADITAPSSLSSPSPSSLPEKQGDTDNAIDASRPERGYQSSVIAPVAAATPTTPATPAEVESGIQESDQELKDVEMEDVAMSISASETPVGSNVTSAAPQTSEEDIEMEDITTNESQSSISENIEPIVSKENAESSEVVGSEKKQAENDHSDASSPTSASDLSPPGAMEEEEDAAVEVNSSVTETKAEETEGVDGETKEEKEEEEEKEVKEEDVRNEEEEEEDVVIKIETDEKSDIESAGQEEHAVHQKTPRIKEIYAEDLPDAEDSSREDEEIKTKEESSNEIDQDEDTAHEEAEDGATSVDDEETASVKTGRKPRKIKTSIPIKRKRRSGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2V9</accession>
    <name>A0A9P6N2V9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_002208</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000154">
        <property type="protein sequence ID" value="KAG0021528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N2V9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051059">
        <property type="entry name" value="VerF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626">
        <property type="entry name" value="MIP31509P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40626:SF11">
        <property type="entry name" value="ZINC FINGER PROTEIN YPR022C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="562"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="596"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="31"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="155"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="528"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="40"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="155"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="168"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="228"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="238"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="274"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="305"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="341"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="368"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="417"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="481"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0021528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="647" mass="71601" checksum="376779CE05FB2F3F" modified="2023-09-13" version="1">MHANTAQVQVQIPYYSLSSVAMNSNLGFGGNHHPIDHPGHPANGNTNNTATPLHPYHPSNNSTFSNQFHHHHNSHQQEHHGQQQTYNASSQHSHNNNNNNNHTYHADLQKTIPLQHQVDIYQPPHQNLDSDLMNPIMNRQLNNQYASTYHNYHYSSQQQHPSYHYNKQQQQQQQQQQQQQQQQQTEQQQADQIRSNASTPTPTLSLSTVSSASTPSLSSNTLTLQSSHDYTYSNNRQTSPASSIATSSSTFHVPASPEQLTIGSHLPSPLATMPTWTTNNGVDQELSSQQQQQQSMSPAAREHASFTSSPKNDRSSSYYPTQAPHLYSGPQEHQQQQQQQVWVASMSSDASSQDILEQDRHQQHHQRSYSQSSRNSSALGSYANDGHNHAQPSVASQQQQQQQQPNLPAMGGLPLLSPTSMLQSDYQPSSYPMNMHEAPTVMSHADYPNNSNDSRYGPIRTSHQKKGSRTSVGSQRDFTTRTRTGSVNSTSSGSSNGVLSSLTNTLGSTSIGGAATTTPAVGLTLTAAHQQDEDEDSDSPTTIQMRPRTNAAPRKAVAARVFECSVPGCTKAYTQLHNLKSHERTGHTPVIKLKPFHCIIEGCTKAFSQRKSLALHIKTAHADFKFKPFKCTQDGCNKAYTQLHKNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N300</accession>
    <name>A0A9P6N300_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Amidohydrolase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_001530</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the metallo-dependent hydrolases superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000135">
        <property type="protein sequence ID" value="KAG0021888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N300"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019748">
        <property type="term" value="P:secondary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01292">
        <property type="entry name" value="metallo-dependent_hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032465">
        <property type="entry name" value="ACMSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240">
        <property type="entry name" value="2-AMINO-3-CARBOXYLMUCONATE-6-SEMIALDEHYDE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240:SF28">
        <property type="entry name" value="ISO-OROTATE DECARBOXYLASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="2 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="292"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="327"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="382"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="domain" description="Amidohydrolase-related" evidence="6">
        <location>
            <begin position="4"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="444"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="573"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="587"/>
            <end position="604"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU366045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0021888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="665" mass="73686" checksum="B13D1EC8E2A73941" modified="2023-09-13" version="1">MPGEPGAKDILAEAFTTLGLSGIKMHSHVQCVPANHPSMDEVYETCIQFDKPVLIHAGKEPNSSAYKVDAGKICDVSIVEDVLTRHPNLRMCVPHLGMNQYQEFFDLLDKFPNLYLDTTMTFGAFFQSMEDDKPLAQMMRTMLLKHCDRILYGTDWPNIPYDWSRELANLIGVIDGDGEATSAKVGQGEEKGMWRTVEGDMALEKILWRNASAFYGISETELGYSNSNNNSSSSSNNGGQEDGRNSHWKYIRLLDAVGGAGSYFFFTNRDLPNRTINIEDVTLEPLASGKAIWYYVAAVSVFAAAVGLFGIIAALSANRRTVKAFEALYFFSLISQLALIIWGLIWCKQNQTEFDTMCNASKDGLVDLPIPSFASSWTCQKIYMAGILAIGIGGFIWIAFNFYMTNRVIHYARELFSDKANRYKVLGEAAVKELDREQQIPLNYTNVGTNRDDQEYPNNTFHQPSYRDEIEYKDPRSDDSYQSRASVAGFGSYGQEFPQNHQHPVAPGFNHRDSATGLDLVNPYHGEHDIYPAPIAMENIPHPSVPYLPQGSGQSANAYHGDQNVYHVPIAMENIPSQDPPHPPAPNHSQGSGQSFVHTSTNKIVSPFDDDDPVSPVRHSSHDDVKVPLPASPRGDEILLPLSPTQQTPSADVLSPTIGSHSGSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N335</accession>
    <name>A0A9P6N335_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">ATP-dependent 6-phosphofructokinase</fullName>
            <shortName evidence="14">ATP-PFK</shortName>
            <shortName evidence="14">Phosphofructokinase</shortName>
            <ecNumber evidence="14">2.7.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Phosphohexokinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="primary">PFK1</name>
        <name evidence="18" type="ORF">BGZ80_009469</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 14 15">
            <text>beta-D-fructose 6-phosphate + ATP = beta-D-fructose 1,6-bisphosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16109"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="14">Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 14 15">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="14">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 14">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.11" evidence="14"/>
    <dbReference type="EMBL" id="JAAAID010000057">
        <property type="protein sequence ID" value="KAG0023430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N335"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005945">
        <property type="term" value="C:6-phosphofructokinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003872">
        <property type="term" value="F:6-phosphofructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016208">
        <property type="term" value="F:AMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070095">
        <property type="term" value="F:fructose-6-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048029">
        <property type="term" value="F:monosaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061621">
        <property type="term" value="P:canonical glycolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030388">
        <property type="term" value="P:fructose 1,6-bisphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006002">
        <property type="term" value="P:fructose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.460:FF:000007">
        <property type="entry name" value="ATP-dependent 6-phosphofructokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.460:FF:000008">
        <property type="entry name" value="ATP-dependent 6-phosphofructokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.450">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.460">
        <property type="entry name" value="Phosphofructokinase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03184">
        <property type="entry name" value="Phosphofructokinase_I_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009161">
        <property type="entry name" value="6-Pfructokinase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022953">
        <property type="entry name" value="ATP_PFK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015912">
        <property type="entry name" value="Phosphofructokinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000023">
        <property type="entry name" value="Phosphofructokinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035966">
        <property type="entry name" value="PKF_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02478">
        <property type="entry name" value="6PF1K_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13697:SF4">
        <property type="entry name" value="ATP-DEPENDENT 6-PHOSPHOFRUCTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13697">
        <property type="entry name" value="PHOSPHOFRUCTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00365">
        <property type="entry name" value="PFK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000533">
        <property type="entry name" value="ATP_PFK_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00476">
        <property type="entry name" value="PHFRCTKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53784">
        <property type="entry name" value="Phosphofructokinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00433">
        <property type="entry name" value="PHOSPHOFRUCTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 14" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="10 14 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 14" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12 14 15" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="9 14 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="11 14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 14 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphofructokinase" evidence="17">
        <location>
            <begin position="46"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphofructokinase" evidence="17">
        <location>
            <begin position="455"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal catalytic PFK domain 1" evidence="14">
        <location>
            <begin position="1"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal regulatory PFK domain 2" evidence="14">
        <location>
            <begin position="455"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="749"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="754"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="14">
        <location>
            <position position="215"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="137"/>
            <end position="138"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="167"/>
            <end position="170"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="14">
        <location>
            <begin position="213"/>
            <end position="215"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="250"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="14">
        <location>
            <begin position="257"/>
            <end position="259"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="14">
        <location>
            <position position="315"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="343"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="14">
        <location>
            <begin position="349"/>
            <end position="352"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="14">
        <location>
            <position position="524"/>
        </location>
        <ligand>
            <name>beta-D-fructose 2,6-bisphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58579"/>
            <note>allosteric activator; ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="14">
        <location>
            <begin position="581"/>
            <end position="585"/>
        </location>
        <ligand>
            <name>beta-D-fructose 2,6-bisphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58579"/>
            <note>allosteric activator; ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="619"/>
        </location>
        <ligand>
            <name>beta-D-fructose 2,6-bisphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58579"/>
            <note>allosteric activator; ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="712"/>
        </location>
        <ligand>
            <name>beta-D-fructose 2,6-bisphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58579"/>
            <note>allosteric activator; ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="14">
        <location>
            <begin position="718"/>
            <end position="721"/>
        </location>
        <ligand>
            <name>beta-D-fructose 2,6-bisphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58579"/>
            <note>allosteric activator; ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="14">
        <location>
            <position position="802"/>
        </location>
        <ligand>
            <name>beta-D-fructose 2,6-bisphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58579"/>
            <note>allosteric activator; ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRNR" id="PIRNR000533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAG0023430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="826" mass="89612" checksum="9A61F31C593779D3" modified="2023-09-13" version="1">MNNLLVFTDKPNPFESKKAEPAHKDEATNVASLNPALETSGGRKRKIAILTSGGDAPGMNAAVRAVVRAAIVKGCDAYAVHEGYQGNDTTLKGKITLTTLKRHRLGLVDGGDMIKKMEWDDVQDYLSIGGTVIGTARCAAFRERPGRLLAAKNMIKKGIDALVVCGGDGSLTGANMFRSEWPSLLEELVKENELTAEEIEPFAHLNIVGLVGSIDNDMHSTDITIGAVTCLHRICESIDSISSTASSHSRAFVVEVMGRHCGWLALMAGIATGADFIFIPECPPHAGENWRENMCAEIKRHRDLGKRKTIVIVCEGAIDSELQPITAKDLTDLLTERLHLDTRMTILGHVQRGGSPSSFDRILASLQGVEAVEAVLASKPDIPSPMIAMCENKIKRVDLMKAVKLTGDVAKAIGRRDFEGAMELRDPSFIENFKHFLAISSSNPSDTNDNTQSLRIGIINVGAPAGGMNAAVRAAARYSFNNGHKVFAISNGFPGLIAGQIKEMKWMDVDGWIAQGGSELGTNRDQPSLDLGMVSYQLQKFNIQSLLLIGGFEAYTSCIEMYNARDTYPAFCIPMVNIPATISNNVPGTEYSLGTDTSVNSIVTACDALKQSATASRKRVFVVEVHGGKSGFLAVMSGLAVGATSIYIPEEGINLARLQKDVRHLCRRYAEDAETKNQGRIIIRSQEASKTYSTDIVSSIIKEEGHQQFDSRTAILGHVQQGNSPSPLDRTRATRLAITSVDFLVKHARHRSPGSPNVAESSSGPEVFNKDPESVVVAGLHGNKVNFTSVEKLLKHTDLKNRKPTHTVWLECKQICNVLARRTDLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3H8</accession>
    <name>A0A9P6N3H8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transmembrane protein 198</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_007556</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM198 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000039">
        <property type="protein sequence ID" value="KAG0023864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3H8"/>
    <dbReference type="OrthoDB" id="102260at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025256">
        <property type="entry name" value="TM7S3/TM198-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040236">
        <property type="entry name" value="TMEM198"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31247:SF5">
        <property type="entry name" value="DUF4203 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31247">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 198 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13886">
        <property type="entry name" value="TM7S3_TM198"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040396139" description="Transmembrane protein 198" evidence="8">
        <location>
            <begin position="27"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="45"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="75"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="108"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="164"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="186"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="235"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="TM7S3/TM198-like" evidence="9">
        <location>
            <begin position="56"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0023864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="279" mass="29847" checksum="90E71A5AEE0B4C81" modified="2023-09-13" version="1">MTCSIHRQSVALLALLLCFFASTAQADPVSINATLPDIGDSGSGYHITVSSTIVAIVLMAAGFLFAFFGHKFFKITIFLAGFYVFATLAWIALRNLAPSNGYGSNSEWVYVGVSGAAGLLGGLLFLCLWRLGFAAIGGIAGFYLAIFILSWTSSGVISNGTGRTIFIAAFVIIGIILTFFLDRHIIILGTAIVGSGSFFVGLDNFIRTGFSEAFTAFLAGNHSAFSSEYNVTGKVYGMLAGTLGMMVVGACFQYYCHRDSFVPKSYRRQPYAASAYQQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3J5</accession>
    <name>A0A9P6N3J5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">RNA polymerase II subunit B1 CTD phosphatase RPAP2 homolog</fullName>
            <ecNumber evidence="12">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BGZ80_007271</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Putative RNA polymerase II subunit B1 C-terminal domain (CTD) phosphatase involved in RNA polymerase II transcription regulation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 12">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 12">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11 12">Belongs to the RPAP2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="12"/>
    <dbReference type="EMBL" id="JAAAID010000037">
        <property type="protein sequence ID" value="KAG0023910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3J5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043175">
        <property type="term" value="F:RNA polymerase core enzyme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008420">
        <property type="term" value="F:RNA polymerase II CTD heptapeptide repeat phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039693">
        <property type="entry name" value="Rtr1/RPAP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007308">
        <property type="entry name" value="Rtr1/RPAP2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038534">
        <property type="entry name" value="Rtr1/RPAP2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14732">
        <property type="entry name" value="RNA POLYMERASE II SUBUNIT B1 CTD PHOSPHATASE RPAP2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14732:SF0">
        <property type="entry name" value="RNA POLYMERASE II SUBUNIT B1 CTD PHOSPHATASE RPAP2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04181">
        <property type="entry name" value="RPAP2_Rtr1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51479">
        <property type="entry name" value="ZF_RTR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7 12" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 12" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RTR1-type" evidence="14">
        <location>
            <begin position="1"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="17"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="168"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="238"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="33"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="168"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="181"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="291"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="316"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU367080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0023910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="333" mass="37182" checksum="817FB9777EC08C04" modified="2023-09-13" version="1">MARRIVPTMKDDIVVDRSPLVDQYLPPKPKPKPSTSAPSSSSSKDKSKYSEDLTKKQVLLQNNIALHKKYEAMVLDWTLILCDPVSEDTLGEADLKGKFRISLSERKVFDISELKKYCSSKCLSASRWFESQLSEEPLYLMDSESAYLRTTRVSIVPLGMDITEFHAQRSKDAPKKEEKSTPAFSLPPLSSPTLESTATSSAPSQKQPQSLGNEYVQSLLASVPETPSFIKIVEHDTTGVTPLEDQHMNGEDSDDDEEENGHQYDSVEGFRIPIKPRSQKPLDSIGIARMSDSDAKTLENKMSRVTLSDDQYMHPQDQSVSRTASSTSMDTRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3V3</accession>
    <name>A0A9P6N3V3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ATP-dependent (S)-NAD(P)H-hydrate dehydratase</fullName>
            <ecNumber evidence="7">4.2.1.93</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">ATP-dependent NAD(P)HX dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_010510</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(6S)-NADHX + ATP = ADP + phosphate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19017"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:64074"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.2.1.93"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>(6S)-NADPHX + ATP = ADP + phosphate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:32231"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.2.1.93"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the NnrD/CARKD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.93" evidence="7"/>
    <dbReference type="EMBL" id="JAAAID010000074">
        <property type="protein sequence ID" value="KAG0023049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3V3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047453">
        <property type="term" value="F:ATP-dependent NAD(P)H-hydrate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110051">
        <property type="term" value="P:metabolite repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046496">
        <property type="term" value="P:nicotinamide nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01171">
        <property type="entry name" value="YXKO-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01965">
        <property type="entry name" value="NADHX_dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000631">
        <property type="entry name" value="CARKD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00196">
        <property type="entry name" value="yjeF_cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12592:SF0">
        <property type="entry name" value="ATP-DEPENDENT (S)-NAD(P)H-HYDRATE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12592">
        <property type="entry name" value="ATP-DEPENDENT (S)-NAD(P)H-HYDRATE DEHYDRATASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01256">
        <property type="entry name" value="Carb_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51383">
        <property type="entry name" value="YJEF_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 7" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0521">NADP</keyword>
    <keyword evidence="1 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YjeF C-terminal" evidence="8">
        <location>
            <begin position="16"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="171"/>
            <end position="177"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="211"/>
            <end position="215"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="230"/>
            <end position="239"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="240"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0023049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="331" mass="35855" checksum="297E03944C47D446" modified="2023-09-13" version="1">MSKLTPRQQEAATVPTYAQYRSLIPPLSSGLHKGQGGRVGILGGSAEYGADICHIICDEDAATTIKSYSPDLIVHPYIKIRATTDCDDEKKTKKIWTQTFDDICAVLKRIHVLVVGPGVSRDKGMLQCAKHAIEVAKELDIPIVIDADGLYLIQHEPDLVQGYTKAVLTPNVAEFDRLCNAKNVDTDDEDSDEPAVQRLSKAFGGVVVIQKGHNDVISDGKTLCTVANEGGLKRSGGQGDILTGLIATSLAWGTAYEKGVWSHSHPVSSEDIALIACFGACVLNRECSRVAYEKYKRSVQSSDVVQEIGGVFTIFYDKARPNADWGEALYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4C9</accession>
    <name>A0A9P6N4C9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Mediator of RNA polymerase II transcription subunit 1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Mediator complex subunit 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_005472</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the Mediator complex subunit 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000027">
        <property type="protein sequence ID" value="KAG0024166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N4C9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051999">
        <property type="entry name" value="Mediator_complex_subunit_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019680">
        <property type="entry name" value="Mediator_Med1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12881">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12881:SF10">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10744">
        <property type="entry name" value="Med1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0010">Activator</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 7" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Mediator complex subunit Med1" evidence="9">
        <location>
            <begin position="149"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="706"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="706"/>
            <end position="724"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF10744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0024166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="735" mass="80971" checksum="F5E603C58DB7A6CB" modified="2023-09-13" version="1">MPNTTNATTVQEHLRELQALVQDSLKHWKLATTAATATALAGQSNPDRLTNELHPLGPVQVGTLQRDFKEKIAAIRSICLSFAQGPLQQSLNGSDSSSAPALRRYSTLLKEETQHDEALSFVKLSMKQCQNTLRAASQDGNIKTEHLISTIRDMATELGLECYLETGSRVDNLVSVSTLTIGGNVIVIDIDVESTGAILRVKVSYASEIHQDERIDRLLAHNLRCKCGKLLQTTPGSGKVSEGNLTHLPDCSRDFDAFSKNLRALATLDSFSKKYPNVDFFHNMRSIDVDFKELFKREMKITARDLHKVLTQGHGIPMTHAVLPGPSVAYWASKADLLDVSWDDLSTAIEQGANEKVKIPFHRISVTMEESTTFSSGYLPVERSGFLLSEEETYGLNSVPYGSIMNDQGSVSATTILQQPLKWIVPNIDSTVEATYVAVLHPPVVVAEDVAKQLAAFSNQAGLNTTMGFHKDPGYLSLQECLINQGTEQTQWEVTLDQGANAVRQIYSFDRTKNEARLIHRVPFTHISQIYICTKLLRQQLTFNTLFQSCFRETVPVDETKKRLATIHPGTTDDHGLEVSIIVQTPQPPNTILASFLNPYTETNMILEILIDAGTGLPTVRLVNETTTSSAVGVTSDAAMIGGGINGDSGMNMNNMSDVNNSSGSQDHQQFLIGEKLTRVLQTCDSIPILVRWILKRSLSWMKGRSSIQGKGQSQLGRRTSSYTEEGGILKRPRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4X7</accession>
    <name>A0A9P6N4X7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Arginine N-methyltransferase 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_008578</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000047">
        <property type="protein sequence ID" value="KAG0023664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N4X7"/>
    <dbReference type="OrthoDB" id="9983560at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019702">
        <property type="term" value="F:protein arginine N5-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000135">
        <property type="entry name" value="Arginine N-methyltransferase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051038">
        <property type="entry name" value="RMT2/GAMT_Mtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026480">
        <property type="entry name" value="RMT2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32379">
        <property type="entry name" value="GUANIDINOACETATE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32379:SF1">
        <property type="entry name" value="GUANIDINOACETATE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51559">
        <property type="entry name" value="SAM_RMT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040151275" description="Arginine N-methyltransferase 2" evidence="7">
        <location>
            <begin position="23"/>
            <end position="983"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="8">
        <location>
            <begin position="119"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="5">
        <location>
            <begin position="641"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="domain" description="RMT2" evidence="9">
        <location>
            <begin position="766"/>
            <end position="983"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="719"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="719"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="738"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="755"/>
            <end position="768"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0023664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="983" mass="108979" checksum="87FDBD359602BC53" modified="2023-09-13" version="1">MHSKSLISLALLSTITTVTVAAASSHRQCRCLPSQSCWPSESSWSALSQSVGGRLIATKPAAYECHDPHYDSAKCDEIQKGYYYDYWRQLQPGAVQQTNWEVIGNKGCLGFNQTAPCYQGAVPLYTVNATSIEDVQSAVRFAAKNNIRLVVKNTGHDYIGRSIGASSLNLWVYFMKNFSFTDSFVPEGAPSGSSGIGAIVLDSGVLWKDVYKAADEQNVIVVGGAEGTVGTSGGYCQGGGHSPLSPLHGLCVDNVLQYKVVTADGELKVANSYQNKDLFWALRGGGGATFGVVVEATYKTHPAVKSLNYATYLLSFNGTETRHKLINNFLSHQAKWSDEGWSGYSYLLNDYIAVIYYLPDTDVNTANSSISPFFEYAKSLGNVQVEGIINNYPTFWETFLSAPSSPNATNAGANTLLGSRLIPRRNFESCKGVDQLTNAIIDIQQDLVNFGNTNGTIITHLVAGGEVSKGNSEDTSVLPAWRKALMHIVASTGWADDTPVAVQHLFARKLTQATQRLRDLSPGSGAYFNEADANEPNWQTNFFGSNYARLKAIKDEVDPHGLFVCRNCVGSEDWNMADTEEHTHRNPVPESNLVKTEEIIEASSEEVAKSQALMEAVAAGKVEKVEELLKDGANHSARAAHGRTMLHFATMIGSLPIVKLLLSYGHPWNLVDDDYKSVGDYAKSFNHPEIYDFLLEEGVRTELLMGLIQRKLRAELYEADQGDDDEDEQEKKKEGQTEETSGQSETTTTDNESEPATKKQKVDDKKEVPNASYLAQPLQYTEDGDRLLDAEKNGVMMGWELPLMVRHAEVISPEEGLRVLNVGFGLGLIDKELQKRSPSQHTIIEAHPDVYAHMLKEGWDKKPGVKILFGRWQDVVDQLEVYDGIFFDTFGEYYEDLRAFHEIVPNHLEEGGIYSYFNGLGATNEFFHAVYNRISELELGEMGFSVEYEEMDIGLKEEEWNGVKRAYWTLDKYYLPICRLDGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4Y5</accession>
    <name>A0A9P6N4Y5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Mfs transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_006067</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000003">
        <property type="protein sequence ID" value="KAG0024794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N4Y5"/>
    <dbReference type="OrthoDB" id="3026777at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23507:SF1">
        <property type="entry name" value="FI18259P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23507">
        <property type="entry name" value="ZGC:174356"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="151"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="181"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="206"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="246"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="277"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="362"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="399"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="573"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="631"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="664"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="431"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="505"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="520"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="548"/>
            <end position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0024794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="695" mass="75930" checksum="744F3E7D10F6AF0F" modified="2023-09-13" version="1">MTHHERGQRLNIPQEPSQDTIWEEGGEDSPLLPPHETPEVVDPTSAYVKILAEYLPWYKRPSAHWLFPVYGLASVSAGMLTSSIGQFQAALLCKEYMNRHPPINTTELVASAASEFSSFLLESAAGNSAFPLRPAPQCRVPEIQAFTAKTLGIIEVIGGIAAMLTIGYYASLSDKHGRLKIMILGFANNLLMLCAMIAMGKWWDQIGLPLLVISALISGLTGGIGLAATMSLAYAADCTDPSKRSLVYSWLHAGLFMGLAIGPYLGGSITRATGTFLTIICIDIVAALISLSLLIFVMPESIPGKQPAHIRKLYEQVTKSNQKQQDDGDDDSKKPQEQHVPWHSHFLGSLRFFKPDGHNTNLILLAAISFLQTLALKGTFSVLILYTNLIFNWTEYEDGILFSMSSMVRLFSLLILLPIFVHIYRKLTGKNANTATAPPPQPAPYGTAGSHSKNSRRPHGDPDNDDEGPLDLFSNHPDQVIVGGLNDPNVASSLEHLGGAALNLSDDEESFQERRRRQSTANSTATWSSDRTRIPASPSSPTPRKKVPSNSPAAATATQPKEQKLGDLKLDTWIIRVGYTINSLTYIGYGLSTKDWHFYLWSALHATSIISSPSLKSLLTSFVEPSQFGAVLGAFQIIDSIAGVFSPVVISWVFALTVKTRPDFVWYCCAFLTGLCTVLSFMVRQKKFGKSSLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N533</accession>
    <name>A0A9P6N533_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_006098</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000030">
        <property type="protein sequence ID" value="KAG0024089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N533"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0024089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="662" mass="74924" checksum="762C736C09F9272B" modified="2023-09-13" version="1">MFPWTGQGAANAIQDAVVLANCIFNMSDSTSESITAAFEDYYKQRHHRAAEQIERSRENGKIMTGQSWIQPDSVMQKWYMKIYEYRPQIAWLPLIEHRGIGTVLPQENCRRVTEAKRADFLTPRDRVNCLRVSKIFHAAIISDVWHTIDLGRRRHTGKVLSFPVGEALEHNKSHIRVIRFRGVYPSEYLPLIGCQSIRELVLDATADVYGPDILERVLVGFTTLIELSSATLQNLSIRSDSGQLEPGNNLWNALIQCSSLSYINFSGFKVPDENILQFIQICGKALSISLSYMMISRLPPLRSVSDGASNDERISRNFNILARPRELRMWGSFGTGIGLSPVEQAAMFRMCPNLESLTWRSAGDGASSLWLVLGHESPMSDHARNFCATLSKDPWPLTALQSLDLSFCMMKDEDHATLISRVHRLKSYKAVCSQFGPLSLDALIGEGGQPSQRQQHRNTIETLFIDRCPSVTGNMILRILESCPNMKKLAADRITISEIAQGQSWICSGLESLEVYLAADDINRDEAGGNDNSINNESNIAQDISSEEFQRMQRTVYIRLNSLTRLRKLALTNRTSQPCSEKRTLDLRLQAGLGLLSNLRNLMELSFRLGVAQKMSVEEAHWITENWPKLKCMQGVWNEDESVYEEMKDIIKPEQMYFSSRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N554</accession>
    <name>A0A9P6N554_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ribonuclease T2</fullName>
            <ecNumber evidence="2">4.6.1.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RNY1_1</name>
        <name evidence="5" type="ORF">BGZ80_007850</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the RNase T2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.19" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010000041">
        <property type="protein sequence ID" value="KAG0023828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N554"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033897">
        <property type="term" value="F:ribonuclease T2 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.730.10">
        <property type="entry name" value="Ribonuclease T2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001568">
        <property type="entry name" value="RNase_T2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036430">
        <property type="entry name" value="RNase_T2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018188">
        <property type="entry name" value="RNase_T2_His_AS_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033130">
        <property type="entry name" value="RNase_T2_His_AS_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11240">
        <property type="entry name" value="RIBONUCLEASE T2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11240:SF22">
        <property type="entry name" value="RIBONUCLEASE T2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00445">
        <property type="entry name" value="Ribonuclease_T2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55895">
        <property type="entry name" value="Ribonuclease Rh-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00530">
        <property type="entry name" value="RNASE_T2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00531">
        <property type="entry name" value="RNASE_T2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040282517" description="ribonuclease T2" evidence="4">
        <location>
            <begin position="21"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0023828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="345" mass="36327" checksum="EA53BFDB0E451957" modified="2023-09-13" version="1">MKFTTIATSIALAALSVVSAAPLDHVYLARRATCPTNVLSCSSASSGVSTCCLPEMGLLVLTQQWYQGLGPSNQFTMHGLWPDTCSGGQGSSSGCDSSRVYTDVGTRLQNYAGASSQFMSDMNTYWSSYTGDNNAFWSHEWSKHGTCVSTLAPSCYSSYATNEDVYDYFKKALALRAKYDLYGALSAAGILPGSTPKAADMHTAITNAFGVDAEINCSSGVLSEIWLFFYVQNYDEYVPTAPQSTGSCSGSISYPVKSGSVATTTTTATATKTTTTTTKTSTTTASGSIPTGKQSGFCSVSGATVCVSPGSSAYYSKCNNGSWILNQCKSGLYCYSDTTTTTHCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N5C8</accession>
    <name>A0A9P6N5C8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cyclin-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006979</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000035">
        <property type="protein sequence ID" value="KAG0023965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N5C8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000307">
        <property type="term" value="C:cyclin-dependent protein kinase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20558">
        <property type="entry name" value="CYCLIN_ScPCL7-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013922">
        <property type="entry name" value="Cyclin_PHO80-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615:SF117">
        <property type="entry name" value="PHO85 CYCLIN PHO80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08613">
        <property type="entry name" value="Cyclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="156"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0023965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="191" mass="21437" checksum="02E30EC28059F68F" modified="2023-09-13" version="1">MHLQPGSTQISPSPEPTVPTQQEDLQGVILVPEYFHQADMTHLTIMIVRTFTISSLTVHRFIIASVTLAAKAVCDSYCTNSHYAKVGGLSTQELNTLEVEFLSLIEWRVAVEGTVMQRYYVNLVRQHSRFEITESVPHHLSLSNNHQDGDDDEQMNGGSQDSDGDQQNDGSVMAEQDYEEGLRDQWIPMGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SSK0</accession>
    <name>A0A9P6SSK0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007022</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003524">
        <property type="protein sequence ID" value="KAF9997375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SSK0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9997375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="89" mass="9687" checksum="98BF9DCD5D7DB6D0" modified="2023-09-13" version="1" fragment="single">MAQSQTLASPSTTTVVQIPESTKYTSEEMSHESTQVTSMEKKPTGIESLREKLRPLLLYIVSTAQFLDIVNGASVSVAILPIAEDLNFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SSV4</accession>
    <name>A0A9P6SSV4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_006857</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003412">
        <property type="protein sequence ID" value="KAF9998123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SSV4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="264"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="350"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="76"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="95"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="109"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="133"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="151"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="200"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="272"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9998123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="416" mass="45849" checksum="B67A6C7AA66C01F4" modified="2023-09-13" version="1" fragment="single">MQAQVHPDLPFGSASSPSSKHSTLHSRQSSTITPLPLLPTKEHSDIVDLTYGIPHTPSLALKPPHTPPPSSPKTLAAQQTTLPSTPQHPSKEDISSLQQPQPNRSNYSQLQWQQQDQQQQQQQQQQPQQQQQDYTHLTSQDQHAVLEALEPSPTLSATGTSSASARTSVSSPASSVSYLNQNNTLHTSPTPAPAPPASRSDVSAEQNPLHTTTLRPKRSNNVPSNTVDLDSDLQLQEQELENSPQPTSVDFVVTVSTIRTGVIELDTDGAGSSSPTSVSEPSAPLSASPRRASTLDPRRVRRGSQFEDPATGVSRQPQFPQGEFSSRARRRQIYRRNTYSADIASASFNRSDDEMEMDELEEARRRMEVLKKSSSRRTSKWKKDDDTDRVLIGTPISEDHVNYVLMYNMLTGIRVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ST14</accession>
    <name>A0A9P6ST14_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_006555</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003241">
        <property type="protein sequence ID" value="KAF9999522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ST14"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9999522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="136" mass="15629" checksum="1AE7E5AF777DB578" modified="2023-09-13" version="1" fragment="single">SSPQSHGTRAYQAPLLSTYVGSINSIRNLDNEQTRLRPLASFHEDGNVIVESKAKDLLVKVHTQDSEVETLLVEEFEAIKLIPDRKKVIKREEDIEEGGRLYEDDYFGEGQGITTVDESIEEIQMPYSIRRHRREE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ST44</accession>
    <name>A0A9P6ST44_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA polymerase epsilon subunit B</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">DNA polymerase II subunit 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">DPB2</name>
        <name evidence="10" type="ORF">BGZ80_006635</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA polymerase epsilon subunit B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003284">
        <property type="protein sequence ID" value="KAF9999128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ST44"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008622">
        <property type="term" value="C:epsilon DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042276">
        <property type="term" value="P:error-prone translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007185">
        <property type="entry name" value="DNA_pol_a/d/e_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016266">
        <property type="entry name" value="POLE2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12708:SF0">
        <property type="entry name" value="DNA POLYMERASE EPSILON SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12708">
        <property type="entry name" value="DNA POLYMERASE EPSILON SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04042">
        <property type="entry name" value="DNA_pol_E_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000799">
        <property type="entry name" value="DNA_pol_eps_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0235">DNA replication</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="10" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA polymerase alpha/delta/epsilon subunit B" evidence="9">
        <location>
            <begin position="285"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="12"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9999128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="522" mass="59857" checksum="D6A777350F29E4EC" modified="2023-09-13" version="1" fragment="single">MSQVPSSQRIHHQPDRHDEESIDMDSMRHRIDEMEREDDFHQDYSMDHDLMEDNGGDEDDVDITELFHVIDAFSMPRWSWASEVKTFTRDDSLKNNDGMESAHVHHANGSNKLTANASNRLLGTAEEKTAMFRARYQSILQRIMRNEHFAPPVFTGGMKQDRYLKLTQLKALKGRCGERFLMFGMLVKNSVGRFCLEDADDRVELEFNNCKNTAGLFTENCFVLVEGTYTDDNNILVDTIGLPPPELREETKKVFGNIDFLGAPREMRSDEQLCVIASEYEDISFVILSDLWLDQPKTFATLRTIFEGYSNSSLPLAFIMCGSFKSEPFLFNGLESGHYRDGFNTLAELIAEFPLMASSSYFVFVPGPNDPWGSSIIPRPKIPDFYTAKIRSLVKRSIFTSNPCRIKYCDQEIVIFRDDIMNRLLRNCIVAPSGDVVIQKQLVRTIIDGAHLSPLPLTTRQVSWAYDHALRIYPIPDALILADKFEAYNFKYQKCHCMNPGSFPMSDYSWMVYHPASRHSDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SV37</accession>
    <name>A0A9P6SV37_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Metaxin 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">MTX1_3</name>
        <name evidence="11" type="ORF">BGZ80_005274</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metaxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002608">
        <property type="protein sequence ID" value="KAG0006466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SV37"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001401">
        <property type="term" value="C:SAM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03078">
        <property type="entry name" value="GST_N_Metaxin1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033468">
        <property type="entry name" value="Metaxin_GST"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050931">
        <property type="entry name" value="Mito_Protein_Transport_Metaxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019564">
        <property type="entry name" value="Sam37/metaxin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12289:SF41">
        <property type="entry name" value="FAILED AXON CONNECTIONS-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12289">
        <property type="entry name" value="METAXIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17171">
        <property type="entry name" value="GST_C_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10568">
        <property type="entry name" value="Tom37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01180">
        <property type="entry name" value="SUF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="315"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="domain" description="Mitochondrial outer membrane transport complex Sam37/metaxin N-terminal" evidence="9">
        <location>
            <begin position="21"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="Metaxin glutathione S-transferase" evidence="10">
        <location>
            <begin position="182"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF10568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF17171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0006466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="355" mass="40263" checksum="4C46289752F94595" modified="2023-09-13" version="1">MVSELYIYGGAYGLPSIDAQCLAMISYLSIVSHQEYTIVECNDPAVSPSGTTTKTTRQLPMLHDGNNWIAGTNRIISYLSKTGYNADEDLSAEDLAKSVAYSALADESLADAILFSWFADTENFFGATRKAYSNLFSFPSRYILPTQMRKSAVRRVQKYGHSVTIDSEKSTNEENTRIYDLARDCYRVLDRKLGDKDFFFGLKPTSLDAKVFAYLAVQLYPEIPNPQFQLILINQFPRLVAYCDRCREEFFANPPDITLPSEPSPFFTNPISAPREWFRNTFFFHSTTSSSRYVSSGNEKPKKTKEDREFDLKRIYAITFGVVAMATYAIVNGLVAIGNEEEEDEREEHKRSSSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SW70</accession>
    <name>A0A9P6SW70_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">rhizopuspepsin</fullName>
            <ecNumber evidence="3">3.4.23.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BGZ80_004688</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of proteins with broad specificity similar to that of pepsin A, preferring hydrophobic residues at P1 and P1'. Clots milk and activates trypsinogen. Does not cleave 4-Gln-|-His-5, but does cleave 10-His-|-Leu-11 and 12-Val-|-Glu-13 in B chain of insulin.</text>
            <dbReference type="EC" id="3.4.23.21"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.23.21" evidence="3"/>
    <dbReference type="EMBL" id="JAAAID010002367">
        <property type="protein sequence ID" value="KAG0007409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SW70"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.70.10:FF:000115">
        <property type="entry name" value="Lysosomal aspartic protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF51">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 10" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Peptidase A1" evidence="12">
        <location>
            <begin position="144"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="16"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="70"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="162"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="353"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="175"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0007409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="516" mass="55143" checksum="6B89992EBD509229" modified="2023-09-13" version="1">MSKLNTFNNISKSKNSHSTPVHPPTSSSSPSSSSTVITTSKIPSSPPTPTLALVKNSIPDTDTPLEPLQFRSSSSPTPISEEQNDISKITLTPQPNEVKKENNDLSAISNLDRIDQELKGLEQLHKRAYVGVAPVRGNSLDTQWVAAMMIGTPAQEFSVVFDTGSSDLWVPSTSCQSSTCSNLHRYNPGKSSTYTQDGRAWSINYADSSWVSGVLGIDDITVAGITVKGQAFGMASVNTGSTAATGVDGIMGLGLDANTQVGDIRTPITSMLSQNQIEHRIVSVWLNKASNQDASLSDGGEFIFGGVDPSLYTGKITYVPVTSDTDWEISVDQLFVGRKQLSLSNAASSAIVDTGSSYILFPDYLATAFHRAIPNSQYDSKLGWLIPCALANSRTVGDLTFVLGGQKFSVPLSDIVILKSEYNGYCLSAIDSWQELDGQGSQSGILLGDLFIKNQYVVYDYDKKRIGFATKVNTASAGIGLSARNAAVSKWRRGLNHHVQALALGMGASFAAAVFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SW75</accession>
    <name>A0A9P6SW75_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_004664</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002356">
        <property type="protein sequence ID" value="KAG0007429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.80">
        <property type="entry name" value="E3 ubiquitin-protein ligase SopA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024977">
        <property type="entry name" value="Apc4-like_WD40_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056251">
        <property type="entry name" value="Arm_rpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055442">
        <property type="entry name" value="Beta-prop_EML-like_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879:SF9">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12894">
        <property type="entry name" value="ANAPC4_WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23948">
        <property type="entry name" value="ARM_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23414">
        <property type="entry name" value="Beta-prop_EML_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="16"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141571">
        <property type="entry name" value="Pentapeptide repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Arm-like repeat" evidence="7">
        <location>
            <begin position="12"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="784"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="843"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="885"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="927"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="972"/>
            <end position="1013"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1013"/>
            <end position="1054"/>
        </location>
    </feature>
    <feature type="domain" description="Anaphase-promoting complex subunit 4-like WD40" evidence="5">
        <location>
            <begin position="1024"/>
            <end position="1109"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1055"/>
            <end position="1096"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1097"/>
            <end position="1140"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1141"/>
            <end position="1182"/>
        </location>
    </feature>
    <feature type="domain" description="EML-like second beta-propeller" evidence="6">
        <location>
            <begin position="1153"/>
            <end position="1308"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1197"/>
            <end position="1228"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1229"/>
            <end position="1270"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1271"/>
            <end position="1312"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1313"/>
            <end position="1354"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1355"/>
            <end position="1380"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="118"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF23414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF23948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0007429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1481" mass="165292" checksum="34CD86DB89DF5264" modified="2023-09-13" version="1" fragment="single">MSFFDAVKDGFNFDRKCAWYPALRGLDKLIQKGELTDFERIIRDVKFKRDPAFQWGVAQRLGEIASNGIWPDHVRLGALSFLVEIFRDDLVWGQHPSVKQWTLHILNSLESSESTIISDEAKKQVTALNDSIKSKEAAMQKYEKDHTSPYPFMVSRPPEASPLLDRVQKVLDLEGPLRQLKMERAKEQEQLESGADNTYVYISPLAKSGRTTEEFDLDKTVDAFLHSKKKVFLLLGDSGAGKSTFNRALEAKLWKDYKKFGRIPLFIHLPSIDKPEQDLVGKHLRHKCNFTDTQVREMKTYREFILICDGFDECQLTRNLYTSNHLNQPGEWRAQMIISCRTDYGGSDKDVFRPTDRNNPGKADLSQEFQEATIVPFRKEQIDNYVIQFAKASKHAWDAETYLRSIRDIQGLYELVKNPFLLKLTMEVLPNLLGEGDDPTLARVTRVELYDQFIKQWLDRSKNKLRDSDLPQRDKDEFNKLTRSGFEQSGKTFLKELSTAIYDNQGGNPVVTYNTLRDKKTWKDAFFVNTDGKKLLRTSIPLVCSSVQYRFIHRSVLEYGLALSIFDPASEDDILEPALAPSKQSLSRRGSDASSVLSFELKEREEKETVAIEQSLLDSYMGRRPIVNEPSILQFLVERAMKYTKLQDRLRALIERSKTDKKSARIAAANAITILVRVGVQFNGEDLRNVNIPGANLSFGVFDSARFGKADLRKVNLKNAWLRNADLSEANMAGVLFGELPYLQEQFKVTRSAYSPDGDTYAVALGDGSVNIYVTTLWRRIYTLHGHENEITSLAYSATGDRIVTGSLDGTARLWDIKASVNGNLNGAGGPWDTKNVKSIQVLEGHQGDVNSVSFSPKGDRIATGGKDGTARLWDANTGKCIHVLEGHNNPVNIVVFSPKGNQVASGSEGDTVILWNAESGEILRTLKGHSAKITSVVYTFEGDLIASGSSDKTVRLWDTETGDFIRSFGGQDGHDDEVTKVAFSRSGKQLASGGADKKLLLWNVEDGTREHALSHTDMVTDLMYAPEGDQLASGTYDSLVNVWDVVNGEKIDTFEVNNGTINSVVYSPKGKMLTAGCAGKTVRLWDVEAQNYFHPFMAHTDDVNDVAYLKDDEKKVIVTVGDDCDLRLWDMKTGACTKRIPGHKGKVNRVVLSPNGRQFASTSDDKTVRLWNANASELLTLECELESRDPKPTVGVAYSPNGDRIATGFGNDAARLWDTKTGEAVHKLEGHKSVVTSIAYSPKGNLIATGSEDATVKLWNAETGECVHTLEEHTGAVTSITFSKKGDRIASGSEDNTVRLWNVETGETTHVLKEHKDHVTSVVYSPKGDRIASGSDDKTVRLWNVETGDLVHTLEGHESKIGCVVYSPKGDRIATGGQDYDWTVRLWCANEGQLQVIIGGFNAKLNGITWKEEGRNLFLATSSDDKSLRQWKIAKDGSKHTATLCWSSSHEVLTVHDASFQDTQGLTRMQNLLLSQRGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWN9</accession>
    <name>A0A9P6SWN9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Sorting nexin MVP1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Sorting nexin mvp1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">MVP1_2</name>
        <name evidence="13" type="ORF">BGZ80_003149</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for vacuolar protein sorting.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the sorting nexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001816">
        <property type="protein sequence ID" value="KAG0008700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWN9"/>
    <dbReference type="OrthoDB" id="10064318at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032266">
        <property type="term" value="F:phosphatidylinositol-3-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1520.10:FF:000042">
        <property type="entry name" value="Sorting nexin mvp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028662">
        <property type="entry name" value="SNX8/Mvp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045734">
        <property type="entry name" value="Snx8_BAR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47554">
        <property type="entry name" value="SORTING NEXIN MVP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47554:SF1">
        <property type="entry name" value="SORTING NEXIN MVP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19566">
        <property type="entry name" value="Snx8_BAR_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PX" evidence="12">
        <location>
            <begin position="238"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="183"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00072009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0008700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="634" mass="71009" checksum="E5348F222E560F2A" modified="2023-09-13" version="1">MQSDVMTVSFTAPSFEVNDPWSTTPRGLDPLDLSTILSGIPLPRIYTTAFDLAQPVGGKITVSALTKILSVSGLPPVTVDKILNIVVAPTRSRITKGECSVTLALVAMAQKNMDLTIENLTTHREDLPVPHLPGLESLDFGNVNEPDIFSTSPIPRQHHPVNVENSAASVDPWRNSTYISSTTSTSLSNYGSKGSGGYPPAPSYLASPPLAPRELAPQNGTSDPESTRKEMYQWFLNLDTIRMSFAPEKEGIFLFKHTNYIVESKNRQTTVIRRYSDFWWLLEVLSKRFPFRTLPNLPPKRLGVTDEVFLARRLRGLTRFMNALVRHPVLKNDPLVVSFLTEPVELALWRKNVVISTEDEFTTRLPISDALAKQIPMTLELELESIKKRLPASIEYYRNMVNVLDRVQKRTEANAADYTRFSISLNALADCERKCHIEDCYNCGQLSQGYSKVSSHFNQASGLLEEEARETQRGMVEALKRHRDLLISVQELLQRRDQSREGNVAEMLKKRIASNEAKLNTLKTSAANAAAAAASNSGSGSRDSIGLYDAQIEKVKNNIESDQTELQVQNQRSILMQHTLWMEITYYHKSHAQIAGMYQAFVHGQMKTSQSLFDNWKALSPAVHDLPMEVNGFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SX71</accession>
    <name>A0A9P6SX71_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_002277</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001558">
        <property type="protein sequence ID" value="KAG0009542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SX71"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45093:SF2">
        <property type="entry name" value="LISH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45093">
        <property type="entry name" value="TRANSCRIPTION ACTIVATOR MSS11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="100"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="24"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="103"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="169"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0009542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="185" mass="18221" checksum="5DCE6ECAA2EE5860" modified="2023-09-13" version="1" fragment="single">LQQQQQQPFVAPSSSPGILKVTSGPGGGGGSGGGGGGGGGGGGGLGLSLGNSSGGGIPAPNISTFSVTPPLAPPLLSPTIASSPTGFIPTSALLMMARNAQASSPVSPVTPGSSVPFGTPSSSVALPSSVLQQQQQQQQQQQQQQQQQSQQQQQQQQQQQQVPGGLLGGLANNNFNNNNNNSGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXB4</accession>
    <name>A0A9P6SXB4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_002135</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001518">
        <property type="protein sequence ID" value="KAG0009713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXB4"/>
    <dbReference type="OrthoDB" id="2443849at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040227870" evidence="1">
        <location>
            <begin position="29"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0009713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="181" mass="18334" checksum="89ABB19990DDE7BA" modified="2023-09-13" version="1">MARTTPFSVLLIASFAFTLTILASQAQAQNTTKAECEPLHELYKTWVSPCTNNGTSIPTSDADPAWTLCICKNGFYPLAVANEECANAGTGKTSQITTASLDALCVNATGYIPAASQTSSSDLAPALASATAIASAEATSGASTTANASTSAAGMVTPFSQNFMMAVASFAAMVLATAVAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYB9</accession>
    <name>A0A9P6SYB9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Septin-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_000642</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001137">
        <property type="protein sequence ID" value="KAG0011494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYB9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0085020">
        <property type="term" value="P:protein K6-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030379">
        <property type="entry name" value="G_SEPTIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171:SF8">
        <property type="entry name" value="BRCA1-ASSOCIATED RING DOMAIN PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00735">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Septin-type G" evidence="6">
        <location>
            <begin position="133"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="552"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="587"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="649"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="649"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="677"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="694"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="728"/>
            <end position="743"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0011494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="765" mass="83400" checksum="A1D7C25EFE3613CF" modified="2023-09-13" version="1">MDTFISTLSNIQSNEILEEYIPSSSPSPDIRLPITLLPTNPVLQQLKDGLSSPLPDPLGLLPPKIKLPAREVTFVNLPGYSSTTNPSSVLSMTDDYLNHHLRAATSIFSPSIPPSQLAWFLITGSGAHSLPTCAFYFVLYELKPVDILYMKLIHERVNLVPIITKSDTLSEKELWVLKKRMIRQLKLNGINFHTFGMSLATVEKMTELHQWGAAPFVVSSRRNQDGSLFESELQLLVNMCLYDRFRCSQEDVARKTIAWREVFGPSETPASATTEKIWNEKSNSIPSPTPSALPALPLNTRPINTTAGELLEAQLLSEYVVYPETISTPPPSSPYQNAIDPTNMAATQAPSSTVSDGLVTGPVGYPNSVPPNHLTSGQEATGLASPHPMAPNPFTPTTTYVPQQSNTDSSAAQARLELIHQSTGMIVDSSTRPSEIMDGNGVNTVHAQLQGSFEELPEPGVKVEIPHSLSTYQPPAYEIMTSLNTQLTAKQQQHASLVFPNGSQVPGAFIVPPDLYQAAILPDIWEAVESGDVATLQRHLNNGASPDQRNTSKSTLLHRAAWQSSQPYPVMHLLISYGANVNLTNENGNSVLQNVLMKHDDPKLIKLLLDNGAEPSVPNKEGMNALEVAALFNKIESVRYLLENDISSSEPDSIQNALQRAKSPDKKATKTLLRSWQSKEGEKKRAELMRRAGPNSSYSSQVSLTQGHDTNSVNSADTNKGGEGNTGSSTEPASTTVSPSPTSNYVAHNKSTSRFNIKSTIFGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYL4</accession>
    <name>A0A9P6SYL4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Citrate (Si)-synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">CIT1_1</name>
        <name evidence="1" type="ORF">BGZ80_000228</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001040">
        <property type="protein sequence ID" value="KAG0012070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYL4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046912">
        <property type="term" value="F:acyltransferase activity, acyl groups converted into alkyl on transfer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.580.10">
        <property type="entry name" value="Citrate Synthase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016142">
        <property type="entry name" value="Citrate_synth-like_lrg_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002020">
        <property type="entry name" value="Citrate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036969">
        <property type="entry name" value="Citrate_synthase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11739">
        <property type="entry name" value="CITRATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11739:SF8">
        <property type="entry name" value="CITRATE SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00285">
        <property type="entry name" value="Citrate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48256">
        <property type="entry name" value="Citrate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0012070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="194" mass="21442" checksum="CA35A76A01B05082" modified="2023-09-13" version="1" fragment="single">MASLRVAFRLPGLAKVATRHNTFAATAIRAYSTKPQGLKDRLRELIPEKREEVKQVKAEFGSKVLGETTVDMAYGGMRGIKGLIWEGSVLDAEEGIRFRGKTIPECQRDLPSAKDGSEPLPESLFWLLVTGEVPTDEQVRGLSAEWAARATLPTFVEDLLDRCPNTLHPMSQFSLAVTALQHESQFAKAYQKGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYM3</accession>
    <name>A0A9P6SYM3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_000204</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001035">
        <property type="protein sequence ID" value="KAG0012101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYM3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.190">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="133"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="394"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="218"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="138"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="421"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0012101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="436" mass="50006" checksum="4B7B32538D75AB77" modified="2023-09-13" version="1">MKHTKEGRPLVLPPIADPPDGQSAADPLIAFKKEVKDHLLRYHGSAPVDYKCPVTKKLVKVCRDPEHDMNYYCVCRKELLLRTSVKRHFTHCKLALATIASSEPPLTVFNPSPRTNEEGLSAEVQFILDPDYKPEVASGDEFDNDDDGDGGDDGGGGDDDGDVDVDVDVDVDVDVDVDVDGGEGRNDGEDENVVEGAIENKENDNVGRSENKADMDEFTSEGQELRAMRRLLQQLQREQQALKEEQRALKEEQRALKEEQRALKEDRQALKRDQQQFEQRMDVYVKGMLSAQNQQFDAMVQYQEQSQRIMQQRIDTMAECQEESRQNVFEMTQQLLDNQSDFTKTLLNDRVTRMNYRFELIEQSLGLIRDNQQKLRLQFQPEHHRLEDGYVKQTRRATPPQRLPQYINALAGQGRPLHQGHQQEDQPPRARHQDTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYY7</accession>
    <name>A0A9P6SYY7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Gluconokinase</fullName>
            <ecNumber evidence="3 9">2.7.1.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_011688</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>D-gluconate + ATP = 6-phospho-D-gluconate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19433"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18391"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58759"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.12"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 9">Carbohydrate acid metabolism; D-gluconate degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the gluconokinase GntK/GntV family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.12" evidence="3 9"/>
    <dbReference type="EMBL" id="JAAAID010000971">
        <property type="protein sequence ID" value="KAG0012518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYY7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046316">
        <property type="term" value="F:gluconokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02021">
        <property type="entry name" value="GntK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000522">
        <property type="entry name" value="Gluconokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031322">
        <property type="entry name" value="Shikimate/glucono_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006001">
        <property type="entry name" value="Therm_gnt_kin"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01313">
        <property type="entry name" value="therm_gnt_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43442">
        <property type="entry name" value="GLUCONOKINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43442:SF3">
        <property type="entry name" value="GLUCONOKINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01202">
        <property type="entry name" value="SKI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0012518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="202" mass="22030" checksum="D7E480CF528FE9BB" modified="2023-09-13" version="1">MDSGTESIKQGHPMFIIAMGASGCGKSTLGQALANSLGIQFLDGDDLHPKANIEKMALGHPLTDEDRYPWLELIRAKAEQVCADKDSSKSAGCGVVIACSALKKAYRDILRGKTTTCHVPQQIAPLDTLPTYFVYLKGSRDTLLRRMEDRKGHFMKSNMLDSQLQTLESPEGEEGVVVINIEGSTTEQVRSAREGLSSLVEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZB5</accession>
    <name>A0A9P6SZB5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Serine protease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_011202</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000872">
        <property type="protein sequence ID" value="KAG0013255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZB5"/>
    <dbReference type="OrthoDB" id="2333706at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36234">
        <property type="entry name" value="LYSYL ENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36234:SF5">
        <property type="entry name" value="LYSYL ENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040239563" description="Serine protease" evidence="2">
        <location>
            <begin position="22"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="445"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="609"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="445"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="611"/>
            <end position="624"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0013255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="684" mass="76125" checksum="0B3FEF7CCE610503" modified="2023-09-13" version="1">MRPTSITLLSTALLLLAVTNSSQRLAGVANAQVSVPGSFSANFAGSLYHDIPHGVTIENLDVIDFSKIQGAPPVLQLPHIDNAQLLNEERLQRDELVAQGMEPDGVYQFGKAVSIESFDMDSTLSRGRWVPLSVLRQQVSGQKSYIPSRDYEDDVVVWQLEVHSKSALSLNLIFSDFHLPAGTEFYVSGKKKTLGAFTPEINNKPDGVFATAPLAGDRLLLEFYTPKALLEQGIMPRIQLGHIIHGYKPTLLASSSDITAKGIRQQDGSIAPRRRMAGLRDQTRRDFLGVWRTFSQSDDDDDEPIRAMSGKCNVDVACHQSEYYEQSRSVGVILTDFNQKYCTGSLVNNVRQDGRQLFLTANHCAGFADTSAHIVMFNHEKVQCGSTSEVVNEHDTAMGLIKLANYDQSDFTLYEIVEPIPDSYNLYLSGWSALLNPPSSRIRNLPSSSSSFTEESEETISSPWRSPRSSIKENPSPAPEGPPRDQIPVVGIHHPSGDTKKISFFYNGSLPRSCWSECITDDYFHWQIPRWDLGTTEPGSSGSPLFDADKRIVGQLHGGSASCWNKNGYDMYGAVHASFSAPPKKKNKLSTYLDPDETGAKFMDGNSLASARRDTRRREQRREEEESEQYVPLGRIGLEKPLIETKVENPCHSSSGHDQSERMSGVFNRAWQRLTSRYSNLEEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZS1</accession>
    <name>A0A9P6SZS1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_010584</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000751">
        <property type="protein sequence ID" value="KAG0014214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZS1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0014214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="238" mass="26749" checksum="C80ECED9B63CD7A6" modified="2023-09-13" version="1" fragment="single">MNKLSGYSFDVELDTDQPFIIELETGGQSVQTLSGAISLKLSKAESFKVATVAIHGHVGAVVNIDTPHQAVVRETLIKSEVDLIAANDTEGRGVIHLDEGQQYIPFRIDIPNPGELPPTLINKLDTHYVDWKYEIHTTLRRNYFFSTTRVVKHELILRRPITPTCESTLTTSSDRTGQYRSKLTAPGRIVLGQDRLLAKAELKARTKEFMIREVDCALIQLEEIDFTTREPHPEVQNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZV3</accession>
    <name>A0A9P6SZV3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">STAS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_010267</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000699">
        <property type="protein sequence ID" value="KAG0014704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZV3"/>
    <dbReference type="OrthoDB" id="288203at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07042">
        <property type="entry name" value="STAS_SulP_like_sulfate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="entry name" value="STAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001902">
        <property type="entry name" value="SLC26A/SulP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00815">
        <property type="entry name" value="sulP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11814">
        <property type="entry name" value="SULFATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SpoIIaa-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="77"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="126"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="208"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="240"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="334"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="372"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="402"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="434"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="8">
        <location>
            <begin position="489"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="709"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="642"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="722"/>
            <end position="733"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0014704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="733" mass="80392" checksum="EDE7EEBADD2757EB" modified="2023-09-13" version="1">MADRELKEFGRSAVSWLKALPSNGPRLITERLPIIKWLPKYNRGWALRDIVAGITVGLIVVPQGMSYAKIAQLPVQHGLYSAYIGAIFYCFMGTSKDLTIGPTAVISLITGELVTQLAGRMTAPEVAAISCLCVGALILILGVLRLGIILDFFPTTVLVGYTTGAAATIVIQQLPKWLGIPGVNNRDPVYSIIINMFKAISNLSWRDLIFGLVGFFILIAIGLAVDRWGRGRFSIQMLKISRFFIVTVLATIASYLVNLNAPTDSKGNIIPRISILKTVPSGLPHPNVPSVSSEIFGEIVPKLLAITLATVLEHIAISKAFARKNRYAIDTNQELLALGAANVTASFFGAYTVTGSFSRSAVKFQCGVKTPFAGFITGALVLLALFFLTPAFYYIPDAALSAVIMVAVSVLISPPSVFIQYYKVNLWDFLSSQVALWVTIFVSVETGIAAGVGFSLLVLLYRIARPNFRLLRQIKDRPEVFVDEYVGSTFETVPAPNGILVFRIEESTTFPNTETLKTWILEEVYKHTRFGGRIKDASERLWSDDLDVHIRNLRKAAHGANSNVTDDDLPRLRAIILDFSAVNNIDSTGLQGLFDLRDLLRDYAGVSDYPTTFFEVHFVGIQANVLSILELSGITRPVDSIALQKVEVLQEIKNENDDLERQAGDIGSAALSVNGVSPFLKEEGLVHLTIRDAVDSVLIRAENWNRDTQHAENVGSDSDSNSAHKDKTEIHYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T027</accession>
    <name>A0A9P6T027_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_010339</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000709">
        <property type="protein sequence ID" value="KAG0014612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T027"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050562">
        <property type="entry name" value="FAD_mOase_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356:SF2">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356">
        <property type="entry name" value="FAD-DEPENDENT MONOOXYGENASE ASQG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="7"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="290"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0014612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="458" mass="51283" checksum="96D76D016C2D78AD" modified="2023-09-13" version="1">MSDYGAKVVIVGAGLGGLTMAILLEKAGIDYLVLERSLNFQPLGSAIGLGFNIMPLFEQLGILEDLKKISKTLESTAVYKDDMEVIRNVKLKDNKVLTGYDALILPRMELHALLLSRVPAEKVLLGKKVLSILQNDSGVMVRTSDGMCYDADILIGADGTYSAVRQSLYKQLARDGKLPRTDTEQLKVSHTSFLGTTGPLDPKKFPKLTDSSSYCDIVIGTNRHETWRYFTVPDNRICWRVDIQVESTAFEDNDTFRSSEYGPESALLIPEEWRSFRLPINGTLGEVIDATRPECISKVMQVEKVFTTWYNTRTVLIGDACHKMLPNFGRGALNAMMDAVSLANALYEMPSCSPKYIKAAFETYYQERYATMESELTASQHMSTVMAGQSRWDSLIRHMMLNIAPKRFLQKDVEYEASYRPQATFLPIVENRGTLPVKKQKESKKYAALMAAKKAVSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T051</accession>
    <name>A0A9P6T051_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_010252</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000696">
        <property type="protein sequence ID" value="KAG0014739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T051"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0014739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="106" mass="11672" checksum="2A87BDDD6537734E" modified="2023-09-13" version="1">MTGLITDISGRHSNNMKIKVFWLRDARMGDGFGPLLVQVNSKYQLSVSGPSCPKFNNHCNSIYQTGSSSGVSRSLLVPKTPITLTVLNPKDKKEFVNSTTREVSLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T095</accession>
    <name>A0A9P6T095_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">Ribosome biogenesis protein NOP53</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_010582</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">May play a role in ribosome biogenesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
            <location evidence="5">Nucleolus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
            <location evidence="5">Nucleoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the NOP53 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000751">
        <property type="protein sequence ID" value="KAG0014212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T095"/>
    <dbReference type="OrthoDB" id="5072at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008097">
        <property type="term" value="F:5S rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011687">
        <property type="entry name" value="Nop53/GLTSCR2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14211">
        <property type="entry name" value="GLIOMA SUPPRESSOR CANDIDATE REGION GENE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14211:SF7">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN NOP53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07767">
        <property type="entry name" value="Nop53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017302">
        <property type="entry name" value="Gltscr2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="50"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="94"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="263"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="346"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="105"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="276"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="320"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="355"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR017302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0014212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="453" mass="51364" checksum="076CCE03EF59E22E" modified="2023-09-13" version="1">MSAAVEKPAPTGNGLNRGSSRKGKKAWRKNVDITDVEQNLDELRAEERITGGKVHQQSNDALFTMDTKGDGKTRKELLKDRTLKMDEILAERSKIPAVGGRKKPSSTTAPLAASAKKDAKISKAEKARLLALIKRKTSNSLFAPVTKPLGRSGMTDAVKAAGRFDVWGTETQEQEEAEEQTKDSNDFVAEVVTKVPVKAPRSFKQRQKVSIPAVKEAHPGASYNPTMQDHQGLLQLAHNEELRILHDKESVDAKLAYPKELDNMVAFDDQTGGLLEDSEDEDEEEEEEEDATGGDDIAKPKKQKGKKSITERNRLARAAETAKKEAQIKREKELLKQTNKVKEIMKSVEEEEAETERKRLENERKKEEKERAGMKRVGRFNIPKERIHVQLQDELAESLRQLKPEGNVMKDRFQSFVERNLIEPRVPVAKRRRYRLKTYEKHSYKRFDNPNHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1J6</accession>
    <name>A0A9P6T1J6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">quinol--cytochrome-c reductase</fullName>
            <ecNumber evidence="3">7.1.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">CYT1_2</name>
        <name evidence="19" type="ORF">BGZ80_007576</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>a quinol + 2 Fe(III)-[cytochrome c](out) = a quinone + 2 Fe(II)-[cytochrome c](out) + 2 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:11484"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="7.1.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="16">
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
        </cofactor>
        <text evidence="16">Binds 1 heme c group covalently per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome c family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.8" evidence="3"/>
    <dbReference type="EMBL" id="JAAAID010000390">
        <property type="protein sequence ID" value="KAG0018092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1J6"/>
    <dbReference type="OrthoDB" id="5925at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008121">
        <property type="term" value="F:quinol-cytochrome-c reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006122">
        <property type="term" value="P:mitochondrial electron transport, ubiquinol to cytochrome c"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.760.10:FF:000002">
        <property type="entry name" value="Cytochrome c1, heme protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.100:FF:000003">
        <property type="entry name" value="Cytochrome c1, heme protein, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="entry name" value="Cytochrome c-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.100">
        <property type="entry name" value="Cytochrome c1, transmembrane anchor, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002326">
        <property type="entry name" value="Cyt_c1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021157">
        <property type="entry name" value="Cyt_c1_TM_anchor_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10266">
        <property type="entry name" value="CYTOCHROME C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10266:SF3">
        <property type="entry name" value="CYTOCHROME C1, HEME PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02167">
        <property type="entry name" value="Cytochrom_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00603">
        <property type="entry name" value="CYTOCHROMEC1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="Cytochrome c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81496">
        <property type="entry name" value="Cytochrome c1 subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase), transmembrane anchor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5 16 17" id="KW-0349">Heme</keyword>
    <keyword evidence="12 16 17" id="KW-0408">Iron</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 16 17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Cytochrome c" evidence="18">
        <location>
            <begin position="87"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent" evidence="16">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="16">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="16">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="16">
        <location>
            <position position="223"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00029351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR602326-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAG0018092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="308" mass="33681" checksum="901986238A85770A" modified="2023-09-13" version="1">MFRLSAQSTRKAVQRLAVQARHQSTSSATASSMNAKNVSMAAAGVVTVGALAYFSMESVDANMAADGLHPPAFPWEHKKSLATFDHAAIRRGYQVYKEVCAACHSLDRIAWRNLIGVSHTEAEVKAMAEENEYTDGPNDVGDMFQRPGKPSDYMPRPYANDEQARAGNAGALPPDLSLMIKARHGGADYVFSLLTGYQDPPAGVEIREGLNFNPYFPGGAIGMARVLYDGLVEYEDGTPATTSQMAKDVVVFLSWAAEPEMDERKKMGMKALTLLGILTGLSIYLKRHKWAGLKTRKILYNPPTPKKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T231</accession>
    <name>A0A9P6T231_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">GRIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_006148</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000302">
        <property type="protein sequence ID" value="KAG0019221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T231"/>
    <dbReference type="OrthoDB" id="1926336at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.60">
        <property type="entry name" value="GRIP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051952">
        <property type="entry name" value="Golgi-autophagy_related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000237">
        <property type="entry name" value="GRIP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23157">
        <property type="entry name" value="GRIP AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23157:SF25">
        <property type="entry name" value="GRIP AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01465">
        <property type="entry name" value="GRIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00755">
        <property type="entry name" value="Grip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50913">
        <property type="entry name" value="GRIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GRIP" evidence="8">
        <location>
            <begin position="641"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="21"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="103"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="497"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="599"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="121"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="498"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="520"/>
            <end position="538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0019221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="707" mass="78667" checksum="CA284D3E2B095757" modified="2023-09-13" version="1">MFNNLLKKASETSFAALASEALDSRPGSPASAKRPPGSPLVGQLNGASSPVRKASKEPKRSYWFNQIAKNVDQLKEENETLNEELQEARAIIKAMRESLENKAADEFLSPKIPQEKEALGTQDNSSSSASTALRRDPLGAVPVSGTDELAKKTETLESTSASLPVAPAETIGSESIDVSDPAELKEKIRNLTRQLSEAKEQYQQLEVTLAQRTSEVGKQKTDHDEKMKKMKAIFAAANKNLNEYRQSIAVKDEEIAELKTQLENRQPSDEQTNEQNQAIKDLEAELRNQSELAATKLQQMESKFKQSNAQLEKLKIEYQQYKQRASTLLQQQREAVQSDDDSKVRELQNQLDALTKENKSIATELQDAESRRSALEGELQLAMDQIASLESSHEISRRQERQNARQLKDLERALKEAQREREAAESRIASLQELKEAETHNLMQELGGNTKYIEDRLAKKEEENAELHRILDRSSDELAAAKQEIQNLRDIITSSEANTDTVGNTGTNTVNSPNTEQDLRSQGQLHISTTLAPKSSFSPYDIESPISRASSSLSLPADRPPVYSTLSDLLAAKPLVERSPFGDTNANHGATATLSSAKEKEYQVKLSHLTELLNESEANHQRLLEQEKVLKEEIRNLDRAERRQNLSVDYLKNIVLKYLETSDREPLLPVLTTVLQLSPAEVASLRKKTIQSSTSSLVLGGLFGGGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T278</accession>
    <name>A0A9P6T278_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF2415 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_005544</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000273">
        <property type="protein sequence ID" value="KAG0019617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T278"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019417">
        <property type="entry name" value="DUF2415"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43991:SF9">
        <property type="entry name" value="DUF2415 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43991">
        <property type="entry name" value="WD REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_8G05640)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10313">
        <property type="entry name" value="DUF2415"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="209"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2415" evidence="2">
        <location>
            <begin position="250"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0019617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="333" mass="36937" checksum="0F17D7CA43DA33E3" modified="2023-09-13" version="1">MSKTYTSQSQVIRDNCEFLKPKPRVHNQRLTIQHWQLRDLITCPKSSEEFIYVNTSTVNSYNTRTKVTTPLMKDLNFHPTSLTAACGYLAAGGQDSQLMVRQLNSTWFAHTSVGGTINNALCISEHLGGTRLLISNNDQTIKVYSLPGLQKLTSIQLPTAVNYTSVSPDGRRMVAVGDTNQVFLYDISVAGGYRKIGTYTATEASFSCAWNQSSEKFAVASQDGFVSIWDIRHSEKLCKLGSKQQPQSKGATRCVKFSSSGSIDLLMFSEHSSYVNLVDARTFNDRQVVRVAPPNNDEQISGIAISPDRLEHTVLEYDVDTITRRSFPSGSLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2J6</accession>
    <name>A0A9P6T2J6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004132</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000214">
        <property type="protein sequence ID" value="KAG0020474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2J6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="369"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0020474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="402" mass="45583" checksum="C397B113979F07C0" modified="2023-09-13" version="1">MENGGGGSSVWDREIASGLGLSSGLLSSASSIRSVAATIPEMIVVGASGRSRASSISSFSSAEKPQMNQRKPLKGRNRVVNRDAASTDPTASHPATVPRMLRRTTRQSFMDVDLQYMLRCDPNTPNPFQNSSPQLSDPPSLFRPLPPVAAAAHAIAHGAAPWTFHEAARLQKEQEDLRVQYLQFLHQLHIANPHGFLAHMNTFATEYPQEFLQLQSYIQFQEKLAHDQREQQHKQEELMRYQIELEKRNKAEQDLRQFQEFQEMQEKKIQQQKQETLLQEWLIQRQQQRASNRNELDLADLFTLAFKRDHQLVSKVASSPGGIDMLLTPQQQFEFGVFLQAHQQAEDEKKRKEIMSGFAFQNSASNPLFGISPKFGTPTPVTVNDGPRRSDRISSRAPTRYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T388</accession>
    <name>A0A9P6T388_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Mitochondrial protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_001569</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000136">
        <property type="protein sequence ID" value="KAG0021861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T388"/>
    <dbReference type="OrthoDB" id="1552at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024461">
        <property type="entry name" value="CCDC90-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14360:SF12">
        <property type="entry name" value="MOZ PROTEIN REPRESENTS A CHROMATIN-ASSOCIATED ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14360">
        <property type="entry name" value="PROTEIN FMP32, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07798">
        <property type="entry name" value="CCDC90-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="36"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0021861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="318" mass="36019" checksum="F3FCB1BAE55A2F9E" modified="2023-09-13" version="1">MATPRRVLSKGASILKQAHLEQRCANPTLARYKHTTSTGNIGQEDSTSRSNPPRSPCTQGCIEPSTTRTFPLLSASSRYTQLFRTPNSLQSIIFRRSIVTNHNFNTNKIVSKLEKNGFERGQAEGIMRIMKGLIGQHTSRIRKNMLTKGDLENESYLLKAALTELRTELQILRKNDAAALAIRTEIISREIDSLNQKLREDIANVKNDIAIDMNSRKSDVREEQKQLEIRIQSMSNHYMAQLGDMRTRMEAAKWETTRKGMVSIFISATFVLLASRIFMSSKDEKVPDDYIDPYINHANAQNNTDGMVPDSFVVSHRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3K0</accession>
    <name>A0A9P6T3K0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_011680</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000097">
        <property type="protein sequence ID" value="KAG0022604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3K0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025533">
        <property type="entry name" value="DUF4419"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31252">
        <property type="entry name" value="DUF4419 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31252:SF11">
        <property type="entry name" value="DUF4419 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14388">
        <property type="entry name" value="DUF4419"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0022604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="314" mass="34924" checksum="4E8441B4A9F561EC" modified="2023-09-13" version="1" fragment="single">MPVTFAPSKVPAESFNKYQPNVELLSQESLFKGACYDQYNRSDEILQSSFQGLYDIAPKSNGFVHTVTEAYNWHRALIIRPDDVWIAILVQFNFFVNGNAELLRSQFVSHEGQKTLEVQESGNRHTVDFGKMAKDMTAEIDRNIVDPSLREWILPDFTTTTDNDIIGSSLSDMATLFAAEFFSKHASEAQDLGNGARHYDNEAQFGLVLGGASYHRVYNDLIPHGYAEVNVVINDNGTEIPSMMIAGHVGSHISSSEDKELSSTGMRDTVRPASGWWIFTTLSGEKTQASAHCLRAWKAGNVKKVSKVILGKHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3W8</accession>
    <name>A0A9P6T3W8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Vacuolar import and degradation protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_001609</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000137">
        <property type="protein sequence ID" value="KAG0021835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3W8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040458">
        <property type="entry name" value="Vid27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013863">
        <property type="entry name" value="VID27_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040979">
        <property type="entry name" value="Vid27_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040768">
        <property type="entry name" value="Vid27_PH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31913">
        <property type="entry name" value="VACUOLAR IMPORT AND DEGRADATION PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31913:SF0">
        <property type="entry name" value="VACUOLAR IMPORT AND DEGRADATION PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08553">
        <property type="entry name" value="VID27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17748">
        <property type="entry name" value="VID27_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17747">
        <property type="entry name" value="VID27_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101898">
        <property type="entry name" value="NHL repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Vid27 N-terminal" evidence="4">
        <location>
            <begin position="1"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="Vid27 PH-like" evidence="3">
        <location>
            <begin position="228"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="Vacuolar import/degradation Vid27 C-terminal" evidence="2">
        <location>
            <begin position="410"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="356"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="356"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="368"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0021835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="974" mass="110680" checksum="024FE825B7E132AA" modified="2023-09-13" version="1">MNVFRSLGNLIWGNDSNPELIQISSGQFYVYKPAAARQRTRECVYIDSMATIRRTSQPFQFVLAVNRVFEEGEETLQDEEQELEDEKIFFIDRAMNFKKGLSAGATAFTWQGLSSEDAGLEYEFVCDDDTTVYTANNFEITVYQCMYERKHQKSHFSADEEAIMEFQIPANAVDSRSPSRPHSDSSSKRAPKSPTSKKGNSPIKEVEVKHEIDRPGLANIPTTYEGVAEAVGELSLFDARTNLFMKQADDVRCQFLRTAKFTYWLVVVDKDGNQQLAQPVEPRMNPVFSSTHCSFIWNYTDEKHNVFSWLVRFPTMEVLKEFQGVLGECMYETLNHESWTKVPTADQEYMVNTYEDTKMSDSESRGSEDEEEQYSDEGEEEEEEEEEEEEEEEEEEEEEEEDGFKQDKASNSHLAVGYKDRSFVVRGNKIGVFKHNDRDGLEFATTIKNINNSKGKQINPARVVLHEQDTSMVMMDPRDLGTAYKMDLEYGKIVEEWDLSGTSGVLNLVGDSKYSHLTNNKTMVGHSNTAMFRVDPRLSRSKIATTEFKQYAKGNNFTCVTTTDNGSIAMAGSKGEIKLFNSIGKNAKTAVPGLGDPIIGIDVTGNGRWVIATCRSYIMLIDVLNPGNKKLGFDASFPAKDKPKCIKLHLQPQHVAAMKQAVSFTPARFNMGQNEEEKTIVTSTGPYVITWNFRRVKNGHYDYQIKQYSDNIVADNFKFGQDRSIIVTLPHDVTALARRSMATPEDTFKIIHSSRFLFDVMSSSASPITNAVLLTLFPRICRLDEYLAGHLEFEFVNEHDSTDFKELLHNTLVANNTELAKNIKSDTTLNKPFPCENKPNTEGNQNKIVDQAIELTCPNNRSWFSGSFNILALGYSNSRRSQSQQAEKYFVNTLEAFVRSPLWETLLKRFIFIFVFASVSVSSQVYNMYMVHVYVCGTSKQLLLPNHWSGYKRTSYNKEIDTEKFAAIAEKVCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T4E6</accession>
    <name>A0A9P6T4E6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Lysine--tRNA ligase</fullName>
            <ecNumber evidence="11">6.1.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Lysyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BGZ80_006661</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>tRNA(Lys) + L-lysine + ATP = L-lysyl-tRNA(Lys) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:20792"/>
            <dbReference type="Rhea" id="RHEA-COMP:9696"/>
            <dbReference type="Rhea" id="RHEA-COMP:9697"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78529"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.6" evidence="11"/>
    <dbReference type="EMBL" id="JAAAID010000033">
        <property type="protein sequence ID" value="KAG0024010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T4E6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004824">
        <property type="term" value="F:lysine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006430">
        <property type="term" value="P:lysyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00775">
        <property type="entry name" value="LysRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04322">
        <property type="entry name" value="LysRS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000238">
        <property type="entry name" value="Lysine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00252">
        <property type="entry name" value="Lys_tRNA_synth_class2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002313">
        <property type="entry name" value="Lys-tRNA-ligase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044136">
        <property type="entry name" value="Lys-tRNA-ligase_II_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018149">
        <property type="entry name" value="Lys-tRNA-synth_II_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002013">
        <property type="entry name" value="SAC_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00499">
        <property type="entry name" value="lysS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001756">
        <property type="entry name" value="PRK00484.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42918:SF5">
        <property type="entry name" value="LYSINE--TRNA LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42918">
        <property type="entry name" value="LYSYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02383">
        <property type="entry name" value="Syja_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00982">
        <property type="entry name" value="TRNASYNTHLYS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50275">
        <property type="entry name" value="SAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAC" evidence="13">
        <location>
            <begin position="58"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="14">
        <location>
            <begin position="711"/>
            <end position="1031"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="966"/>
            <end position="985"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="967"/>
            <end position="980"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0024010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1038" mass="118394" checksum="07549B14F9520963" modified="2023-09-13" version="1">MNAIGEYMIVITDRLRAGRIGGHDIFKLKSYKIIPFSHNNMSLSDAQTGEEAAYISLLHTHLQSGEFYFSYEYELTHSLQRQAELRGNTQPVWERADDRFFWNYRLQSKLIDHTRRHKDQNLSGFILPIINGFVEIKATDIHKKPFTLVLISRRSRHRAGTRYFSRGVDIDGNVSNFNETEQIVVVDPIVNGTVPIAAGNYIMLAHVQTRGSVPIFWTQINNIRYTPKLQIFDNPQTGSAFRRHFETQKKLYGHQLVINLVNKKGYESPIGAAFSKEVDSQNDPQIKYHHFDFHHECSKMRWHRVSLLLNHFHNDLVDQGYFKAEVSRGAVQRVFQKQTSVARTNCMDCLDRTNVVQSVISRWVLNRQLQEIGILPPSEQLESSEQFEILFRNVWADNADVVSRAYSGTGALKNDFTRTGKRTKSGALRDLQNSIVRYVKNNFLDGARQISRTSSFSFSQTCPSILSVMSASGALRRFPRLWSTRSMSSYSLASNRDSFQMHPHKAQKCILVKGVQSPLNAVRLLSTMAGSSESWVVKPEVRLEELNSLSIKPYPRYQQPKVPAVQVKDIITDYQDTMESGTKDETKKVSVSGRIHSKRESSSKLVWFDLMQDGNPIQAVFNRKNYSGSDREFELAAKVFQRGDIVQLTGHVGKTKTGQLSIFITDSFELLAPCLHSIPTRSGLKDPEKRFRNRYLDFLVNQDALGIMKKRRDVIKFIRNYLDSRNFLEVETPILSTQAGGANAKPFATHANALDMEMHMRVAPELYLKQLVIGGADRVYELGKQFRNEGIDADHNPEFTTCEFYQAYENLEGLFSMTEDMLQEMAKSVTGSTKVLTNISKDETVELSFEKPFRRINIMENLEEKLGTALPDLEREPVAELLEICKEHRVFVSTPHTVPRIMDKLISHFIEPKCVQPTFLWGHPIIMSPLAKDIKLESGRTVAGRFELFVAGKEIVNAYEELNDPVQQRDRFTKQQNDKENGDEEAQPMDLAFCTALEYGLPPTAGWGMGVDRVCQILTGSSHIRDVLAFPTMRALKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MDU8</accession>
    <name>A0A9P6MDU8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_008030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004235">
        <property type="protein sequence ID" value="KAF9993791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MDU8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9993791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="50" mass="5813" checksum="837547FC4A4B6531" modified="2023-09-13" version="1" fragment="single">LSPKHPYPHAINEIVASYRDLVRQYGVNPRQIILGKLQQARTLEYNSIHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MGQ8</accession>
    <name>A0A9P6MGQ8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transcription factor of the MADS box</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">MCM1</name>
        <name evidence="8" type="ORF">BGZ80_006779</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003365">
        <property type="protein sequence ID" value="KAF9998465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MGQ8"/>
    <dbReference type="OrthoDB" id="2284405at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000987">
        <property type="term" value="F:cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00266">
        <property type="entry name" value="MADS_SRF_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1810.10:FF:000002">
        <property type="entry name" value="Serum response factor b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1810.10">
        <property type="entry name" value="Transcription factor, MADS-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050142">
        <property type="entry name" value="MADS-box/MEF2_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033897">
        <property type="entry name" value="SRF-like_MADS-box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002100">
        <property type="entry name" value="TF_MADSbox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036879">
        <property type="entry name" value="TF_MADSbox_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48019">
        <property type="entry name" value="SERUM RESPONSE FACTOR HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00319">
        <property type="entry name" value="SRF-TF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00404">
        <property type="entry name" value="MADSDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00432">
        <property type="entry name" value="MADS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55455">
        <property type="entry name" value="SRF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00350">
        <property type="entry name" value="MADS_BOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50066">
        <property type="entry name" value="MADS_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="MADS-box" evidence="7">
        <location>
            <begin position="61"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="143"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="16"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="40"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="186"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="232"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="250"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9998465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="262" mass="28825" checksum="02E6184AFF4227DD" modified="2023-09-13" version="1">MSAKRNQAIVMGASSNEKDHAPEEGGEDHIDKKFKHDTGAGEDGEDDDEDDDEAPKSGKRAGRRKIKIEYIEDKSRRHITFSKRKSGIMKKAYELSTLTGTQVLLLVVSETGLVYTFTTPKLQPLVTKAEGKNLIQACLHAPDKESTPDRYNAPDQEASPAAASDQDHEEQSSSPTQSSHPPPPQQNMQQNPPYSGSSASMGMYPPPYSHIPFPNQGSPAPYNYPNMGMGYQSPNPNGSQQPPSQYWAPTPQQQQMQGDKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MGX6</accession>
    <name>A0A9P6MGX6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006569</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003250">
        <property type="protein sequence ID" value="KAF9999446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MGX6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="13"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9999446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="135" mass="15087" checksum="7D7AAC5477D366E1" modified="2023-09-13" version="1">MFYPNQLIDFVAAQPKAPKPGEREKSKKRRFSSITSKAEALANDVCSDEDEYQDALKGVDALTAKRKTTDRETRDVERVDTDGVAESITDPNIKPSKGAPRRKRFKGCDELPKTKKSSKRVTFGQPKRLAKSASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MHI4</accession>
    <name>A0A9P6MHI4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006205</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003053">
        <property type="protein sequence ID" value="KAG0001292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MHI4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0001292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="83" mass="9338" checksum="89612BCDDA6A73CA" modified="2023-09-13" version="1" fragment="single">VIFHHGSQKKNEQLDPVLKPAETFPYISHSELEDDEAETGNLRQDPQAHQGHSHPQRSRFPGTILTGLDPGPRVTDVNFEDIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MJ01</accession>
    <name>A0A9P6MJ01_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidase A1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_005846</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002880">
        <property type="protein sequence ID" value="KAG0003139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MJ01"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF51">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase A1" evidence="4">
        <location>
            <begin position="1"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0003139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="261" mass="26695" checksum="6EB56B5F32B5D746" modified="2023-09-13" version="1">MGLWYVAQNVQVPILNILESTNVLSQNVLGIYLEQNSGATLKETAPGGEITFGGVNSERFTGDVTYVNNIASQQWTIAVGGMKVGNTVINTDGAMAAIDTGTTAMLVPQSIANAINGAIPGALTSTSAGGNWFLPCSGNTAVSITFGTFTIDIPYTSLAIQSTAMKTSSGTYCQSAAMFPTGSTATVEEWLIGDVVLSNVYTVFDFGTNAANGGRIGFAKLGSGGNSTSASSSGSPKSVLKPALLLQAAVFASISALFALF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MK85</accession>
    <name>A0A9P6MK85_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_005315</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002626">
        <property type="protein sequence ID" value="KAG0006352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MK85"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0006352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="66" mass="6942" checksum="8571FB017603CF5F" modified="2023-09-13" version="1" fragment="single">MARAQVIEASDGTDSYIPHLHPDSGLILKNAGEPLDTMSLENAQILDDLVGIIITGSSNKSYCAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MKS0</accession>
    <name>A0A9P6MKS0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cytochrome c oxidase assembly protein COX16, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Cytochrome c oxidase assembly protein cox16, mitochondrial</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">COX16</name>
        <name evidence="13" type="ORF">BGZ80_005170</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. May participate in merging the COX1 and COX2 assembly lines.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the COX16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002568">
        <property type="protein sequence ID" value="KAG0006698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MKS0"/>
    <dbReference type="OrthoDB" id="5516033at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033617">
        <property type="term" value="P:mitochondrial respiratory chain complex IV assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020164">
        <property type="entry name" value="Cyt_c_Oxase_assmbl_COX16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17130:SF14">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX16 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17130">
        <property type="entry name" value="MITOCHONDRIAL OUTER MEMBRANE PROTEIN 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14138">
        <property type="entry name" value="COX16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="26"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0006698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="122" mass="13669" checksum="36E2CE2F7E8446E9" modified="2023-09-13" version="1">MVFANKAYGVATPTDRFAQSIKKRPVLYFGLPFLFTIVAGSFALSELTTAKYDVQDSRTKSMSKEEGLKLSAKRKKLDLQEEYWRLQAQDIDDNWEIKRVGSEAAPGVTTSPKFAKEASPSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MKZ8</accession>
    <name>A0A9P6MKZ8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA binding protein, heterogenous nuclear RNP-K like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">HEK2_3</name>
        <name evidence="4" type="ORF">BGZ80_005229</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002595">
        <property type="protein sequence ID" value="KAG0006541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MKZ8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="3">
        <location>
            <begin position="47"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0006541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="107" mass="11421" checksum="A4A2440B45BA4851" modified="2023-09-13" version="1" fragment="single">MSTTTTNPANKDANVAGLHDDQYDQEHYDLDHDHDHTREGGEFDSEAPLTLRALVTTKEAGVIIGKAGKNVADLRDQTGVKAGVSKVVQGVHDRVLTVTGTIEGVAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MLH6</accession>
    <name>A0A9P6MLH6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">2-isopropylmalate synthase</fullName>
            <ecNumber evidence="2">2.3.3.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_004979</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 1/4.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.13" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010002486">
        <property type="protein sequence ID" value="KAG0007177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MLH6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003852">
        <property type="term" value="F:2-isopropylmalate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010177">
        <property type="term" value="F:methylthioalkylmalate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:L-leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07940">
        <property type="entry name" value="DRE_TIM_IPMS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.260:FF:000001">
        <property type="entry name" value="2-isopropylmalate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000010">
        <property type="entry name" value="2-isopropylmalate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050073">
        <property type="entry name" value="2-IPM_HCS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013709">
        <property type="entry name" value="2-isopropylmalate_synth_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002034">
        <property type="entry name" value="AIPM/Hcit_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054691">
        <property type="entry name" value="LeuA/HCS_post-cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036230">
        <property type="entry name" value="LeuA_allosteric_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002086">
        <property type="entry name" value="PRK00915.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10277:SF9">
        <property type="entry name" value="2-ISOPROPYLMALATE SYNTHASE 1, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10277">
        <property type="entry name" value="HOMOCITRATE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22617">
        <property type="entry name" value="HCS_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08502">
        <property type="entry name" value="LeuA_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00917">
        <property type="entry name" value="LeuA_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110921">
        <property type="entry name" value="2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00816">
        <property type="entry name" value="AIPM_HOMOCIT_SYNTH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0432">Leucine biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="7">
        <location>
            <begin position="1"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0007177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="474" mass="50890" checksum="47C491EE8F6AABD7" modified="2023-09-13" version="1" fragment="single">TIAGLARAVPADIQRCYDAIAKAPHKRIHTFLATSDIHLEYKLKITRDECVARAVAAVSFAKTLVDDVEFSPEDAGRSDQDFLCKVLSAVIEAGATTLNIPDTVGYNMPEEYGAMIKYLIANTKGSDKVIWSAHCHNDLGLATANTLSGIMNGIRQVEVTINGIGERAGNTAMEEIVMAVHTHPDFFPVYHTVNTPMFCRISQLVASLSGMVVQPNKAIVGANAFLHESGIHQDGVLKNKTTYEIISPETVGANTVNLVLGKHSGRAAFRSRLQDLGFGELSDEEFQIAFNSFKALADSKKRVTEQDLIALLSDQVSSAAGEKATYVVKSLQVVSGTTFATATVQLLNTETGEVVIDAAIGKSGPIEAVFLAIQRLVGKKIRLIKFDITAVGEGVDALGQVSVKIAEDKSVSGASSESEEHVSDKTNTFDQATYHGHGADSDIIQAATKAYLNSLNRLVANESERLLGERKVDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMI7</accession>
    <name>A0A9P6MMI7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Integral membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004545</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002302">
        <property type="protein sequence ID" value="KAG0007547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMI7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006750">
        <property type="entry name" value="YdcZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34821">
        <property type="entry name" value="INNER MEMBRANE PROTEIN YDCZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34821:SF2">
        <property type="entry name" value="INNER MEMBRANE PROTEIN YDCZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04657">
        <property type="entry name" value="DMT_YdcZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0007547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="435" mass="47919" checksum="1E4AC2A930B33121" modified="2023-09-13" version="1">MQRESASQAAELSDVKVVSRQSSVRSIKQKRMSILDSVIVCSILCVIGGVSTASQGAINSNLGKYTGQGLSSTIVFCVGAITSCIYFLIEVKGRPPANLALMITKAPWWSWTGGILGACFVIVTILSIPKLGAGTTTAIIISAKLVFSCIIDQFGLFGIPHRKYTIWRALATVGLVGEDVILNPNLLVIVQGLGEVPPGQWARKLFTNGKRGQWGLATQFPFIERALHLGWAVVLCDPNHDENKPRNQKTRARHVRRVWEDIVQRSDARCVMYVCFSAGTTAVLDLYRTSKREFVKKVKGIAFLDGEDGRDMGRWMQNHSWSFCQDKPKWKPARNETFIPRLDLAIKDISFIVKPKESVGIVGRRGAGRSSLTLFRIIEAADGYWVRASNPTYAQDRPLDDPMALYSDTHGNALNGGLIEIDSVDIPTLGLKGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMK4</accession>
    <name>A0A9P6MMK4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">TPR-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_004623</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002339">
        <property type="protein sequence ID" value="KAG0007469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMK4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006493">
        <property type="term" value="P:protein O-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000180">
        <property type="entry name" value="Related to UDP-N-acetylglucosaminyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44998">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44998:SF1">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANSFERASE 110 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13374">
        <property type="entry name" value="TPR_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50293">
        <property type="entry name" value="TPR_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="925"/>
            <end position="958"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="959"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="175"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="260"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="603"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="345"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="210"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="229"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="265"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="603"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0007469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1130" mass="126853" checksum="408C75856D1B32DA" modified="2023-09-13" version="1" fragment="single">MSSSKAGHSIGLASGYDPQNTAAAFVREYTSAVQQQQQHIQQIQAQAQAQAQSSQYAKAIQSYPTHLQQQLPPLMQPPPSPNTLSYYYHQDRGWLRLERSGSVDAYHHTELQRARLARGSFSLSDHQYLDRALRYSSNGAYEDTQSTMHHQGQDARAAYYSANPSQEADRVLYATQHQHQHQNQHQPFQISSGQPGVHDYPQHSAHISTQIDQSHLQYQHQQQQHLRQPSSIYSHHVQQPQHQHYSGIAPSYQQQQLLSHAHQPAQYQASHAQLQQHQQIHHALQQQQQQLQQLYSNINQQQAAHLQLQASLEQQQHAPISGYAQTVPSASHLQYPSQSSQQFQLQQQQQQQQQQQQQQQQQQAQVQAQLQQQQQQQQQQQLIQLQQMIYDQHRQGHEQQKQQQQQLLLQQHQHQQQLQQLQQLQQQQQQPVTIGSGPLTVTKVQLPQPSHSQMVIQVQLADGKSQQLVIDAREEEWRDHLLSYAHTLYASESTNPSPASPLIPILQTINTFHESHLPTLLLLACVYYTKRDFKKSLHYNQHILTKDPNYVEAMSNIGTTLRSMGRQTEAESWWWKAVRLRPGYWDAVENLIGVLCSSYGTSETQAPTSTESQAGGTSAAGTDPSKPKFDKPAVATQQPPRYKEALKICEFVEANVLPDPSDPTGEQPPPLPIQHTPRLQNLLYAKGNLKYALGDVAGARREYERSLEIVFGAGVGAMQVVNEIMCLTRMAAGYLRPNAHELEGAMLLLRPEEALQVTQVVFRETSGVLPGLATLAASSTEVGAPSAQSGVSSTLWQQANQTTSTILLTLAKLYQDVMDQPAKAKELAGTDNYVPTMSMLLPLYYLSLSLNPSPSTCNNLGILLSSIPPTAKIFSYPAAAQPLQLQVHANGLVVPAPVAPAYPITGQALALQFYHYGLQLDPRHPHLYTNLGSLLKDMGQLNEAVSMYEKAVECNPKFDVALANLGNAVKDLGKVQESIQWYLRAVEINPNFSEAVCGLVNALGGVCDWRGRGGVGPVSVTAEGQLMIMNVSLTDKQPSSGWMGRVSEIVEKQLTEGALWGVGLVRVFRQQLWQMILRAFLDSDPRHPDARLWQARLDGWINRTDAKDRRNEGGWIIRLLERATRRLQRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MML7</accession>
    <name>A0A9P6MML7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">PHD finger protein 14</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">PHF14</name>
        <name evidence="8" type="ORF">BGZ80_004346</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002224">
        <property type="protein sequence ID" value="KAG0007701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034732">
        <property type="entry name" value="EPHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050701">
        <property type="entry name" value="Histone_Mod_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13793:SF107">
        <property type="entry name" value="BROMODOMAIN-CONTAINING PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13793">
        <property type="entry name" value="PHD FINGER PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13832">
        <property type="entry name" value="zf-HC5HC2H_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51805">
        <property type="entry name" value="EPHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="7">
        <location>
            <begin position="472"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="6">
        <location>
            <begin position="896"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="196"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="257"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="337"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="408"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="780"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="971"/>
            <end position="997"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1016"/>
            <end position="1042"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1062"/>
            <end position="1122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1166"/>
            <end position="1185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1193"/>
            <end position="1289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="11"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="60"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="72"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="104"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="141"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="204"/>
            <end position="224"/>
        </location>
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        <location>
            <begin position="277"/>
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        </location>
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        </location>
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        <location>
            <begin position="434"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="971"/>
            <end position="981"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1062"/>
            <end position="1094"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1104"/>
            <end position="1122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1206"/>
            <end position="1215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1243"/>
            <end position="1256"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0007701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1371" mass="149473" checksum="BC9B18964935BD44" modified="2023-09-13" version="1" fragment="single">YSDMPMMMMVEQQQQQQQQQQEQDSQNHALPGRFIKDVSTHPLHRGLHNQYQNQEHPMALPLPPPPPEHIPVTDPADPLPLLATPSPDIIQLLDDQQFPIADNSIPSQEHAQLTTHRTRHQSQSLQGQHTLSSRPQRQRKTTTGSTPGKGSKSPVPTSVPESTSDPTIATMTVAPNIPNGTETAPATVPAAITQLPYTQSDPSPDQPIPAAAPTPGPVLVPAPQPYLGESADSNLPLSVISHSTNSTDVGQVIPTSQGLKAIPGPLESIQDSQNPEQQTQQQQQQQQQDMVENDVSPGGKEAPMVNESADPELVHPIAPVAMPEGIVLEWEAQPEPDPVGAGIKRGSRQMSSVSPTVLSSGMTKEISVMPAKKKAKIEPTKKSVNDTASLFQKIFADRDPGKRKIKTKSVHEIPMDLAADEDDSDFEDTKVDSNDDDEDMTIPDDAASEDDVSPDQQEVFNDEQDLLTALWQWSCVCCPSKDGAFRRLIPDDPSGGWVHVVCALWLPETTLGDPDTVDRISVRDIPEKNWNLVCYMCSDPQDAAMGACVQCDAGQCRKSFHITCAQGYSLLETIEDSDMADPYFMYCKQHGVADGHPKLNGWAKWVKQRDAFLKKWQEEQGRKRTLKLIEMEHSGYGNEDGEGIVELFEHSYSRFKEARERRIARERSELSRQYSIGYYLDSKIDKSRSRLEVISTKAEQALLEQRRIEAHTRNLLSSLLECAHYLESVDAGQLEAPLSVDTTLAWYNSLPDTSRWKSDIQDIIETIDIESLACDNPYTHPGSNGAVDSGLDDSESGLRHGRSSKGIYGKLSKKGSRSTHGAGKNVKSKKVHPKPTLANKSQLPVVFTSSRGRLIKRDYSDPDECYPTNKSSGSYGANYHSGQLNGMSAVKMARPIVPCTICHQLTLPDHKLELERDANGVLTPMAIKSLNRMVSCDTCHRQFHPKCLDPPMARVPPRGYSWNCEDCDSSGDSQGSSGASSPTIAGHHQQHHHSQSSDLDEALMVLADTAMTISASSTKYPSEAPVRAPKRPLGGHGHEATTNSYYSNSAIAGDMPLKFKESKPKKIKTEGSDKPKMIKPKAKDTMAKGDADKTKVKKLTKAKGSQSDMMSTNGSGAASGQPLSFKPAIAPIIRGNLRIYPPGPHIAPKLSSVLMKQVVINDDITQSDKSQVKAKVSKKTTEEKGALYARQEKAGVTAVKKKSSKSETTAKTTSTKSKKLEITTAASKGKTVDTTHKKRASNRDSTPASPTSPNSDKTVKIPKGSKEKATVRRGSLPAVPLPPPPKPKEVIRYTVGEKTVEELTAKEDVEIERRENIKFRKLRGRTLTMPAPPQEALLNASTLAAEAAAAVAAAAAAANKKAAEEAIESAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMR4</accession>
    <name>A0A9P6MMR4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Succinate-semialdehyde dehydrogenase, mitochondrial</fullName>
            <ecNumber evidence="3">1.2.1.24</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">NAD(+)-dependent succinic semialdehyde dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">UGA2</name>
        <name evidence="10" type="ORF">BGZ80_004094</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Amino-acid degradation; 4-aminobutanoate degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.24" evidence="3"/>
    <dbReference type="EMBL" id="JAAAID010002127">
        <property type="protein sequence ID" value="KAG0007904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMR4"/>
    <dbReference type="OrthoDB" id="310895at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004777">
        <property type="term" value="F:succinate-semialdehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009450">
        <property type="term" value="P:gamma-aminobutyric acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07103">
        <property type="entry name" value="ALDH_F5_SSADH_GabD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000004">
        <property type="entry name" value="Succinate-semialdehyde dehydrogenase I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000063">
        <property type="entry name" value="Succinate-semialdehyde dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050740">
        <property type="entry name" value="Aldehyde_DH_Superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43353">
        <property type="entry name" value="SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43353:SF5">
        <property type="entry name" value="SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="9">
        <location>
            <begin position="359"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00030806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0007904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="505" mass="55323" checksum="B281B21D23251B2A" modified="2023-09-13" version="1">MIAIRQPIGVVGVITPWNFPNAMLTRKFGAALAVGCTVVTKPASETPLSALALMELGKRAGLPKGVVSIVTTHKHTKDIGKHLCESHDVAGISFTGSTAVGKHLLKQSADTVKKISLELGGNAPFIVFEDADIDKAVDGAIAAKFRSSGQTCICVNRFYVHSSIKDMFSERLRDRVRKFQVGSGFDKETTHGPLITEGAVQKVHSHVEDAIEHGAKLLVGGDPKENIGHGYFYPPTVLGDMKNNMRIAREETFGPVAGIFEFETEDEVLEAANDTRFGLAGYFFSRDVGRCWRVAEKLQLGMVGVNTGLISSEVAPFGGIKESGIGREGARQGLDEYTQYKLQRLGFLAFSSLIPQMSYSIRFVTTPEDLAKCHDVRMRVFTDEQGYDADVEIDEIDSECLHWIAVDQNDQGAGTARLYKYSPTVGKVGRVAVLLSARGTGLGRLLMESLEKYVIENCEFKTLALSSQVPRQGFYEKMGYAAQGEVYLEEGQPHIRMEKRLSQSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MN23</accession>
    <name>A0A9P6MN23_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Mitochondrial carrier</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_003554</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001947">
        <property type="protein sequence ID" value="KAG0008344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MN23"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46080">
        <property type="entry name" value="MITOCHONDRIAL SUBSTRATE CARRIER FAMILY PROTEIN J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46080:SF18">
        <property type="entry name" value="MITOCHONDRIAL SUBSTRATE CARRIER FAMILY PROTEIN J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="5">
        <location>
            <begin position="89"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="5">
        <location>
            <begin position="207"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="302"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="307"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0008344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="334" mass="36358" checksum="FD4E3F1CC07C060E" modified="2023-09-13" version="1">MATVQVENSAIIPAPQKKVTLGPANVIAYMFQGTGVFMCLGPTKLFRGLGPFLLTSLPSQFVYLGVYEHATTVIERNFPDHHNSNSAMREVAVAGTAGFLAEAVSATLYVPTDIISQRLRVQSELKGGAHLTSIDIFKSIYRTDGIRGYYQGFVATLLAYTPSSVTIWAGYEATKKVLYNQLSARERNQIQQGNPDGFFAKYRLSQNNMFIVGLSALNGSVLSLVVSSPFDMVRVRLQLLDSYHKEQAEQLKKGWWSMAKLIAKEEGVRGFFKGMAPKIMAAIPGGIGYLFAYEYIKENLEGDSSDSKSSATSSSSTPATSSVPSILPPTFSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MN61</accession>
    <name>A0A9P6MN61_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NineTeen Complex (NTC) component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ISY1</name>
        <name evidence="4" type="ORF">BGZ80_003995</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ISY1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002092">
        <property type="protein sequence ID" value="KAG0007985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MN61"/>
    <dbReference type="OrthoDB" id="1739576at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000350">
        <property type="term" value="P:generation of catalytic spliceosome for second transesterification step"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.660:FF:000001">
        <property type="entry name" value="pre-mRNA-splicing factor ISY1 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.660">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029012">
        <property type="entry name" value="Helix_hairpin_bin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009360">
        <property type="entry name" value="Isy1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037200">
        <property type="entry name" value="Isy1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13021">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR ISY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06246">
        <property type="entry name" value="Isy1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140102">
        <property type="entry name" value="ISY1 domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0007985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="235" mass="27384" checksum="6CE23FF7C42E62BF" modified="2023-09-13" version="1" fragment="single">SMLYRFREAKNAELGGSKKLERRPYRISEVTSLAEAEKWRRNVIGEISKKVSKIQDSSLSDFQIRDLNDEINKLMREKYRWEQQIKDLGGVDYRITGPKTFDAQGKEVPGARGYKYFGRAKDLPGVKELFQPQPLTLKEKTRAELYRNIDGDYYGYRDEEDGTLLEFEKEQENIAMAKALEYAEEDEEDSEHGMEVDGQTEKAKSLGILYVPSQKEVEDYLVKRRKQAILDRYVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNI6</accession>
    <name>A0A9P6MNI6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Lipoyl-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_003169</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001821">
        <property type="protein sequence ID" value="KAG0008689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNI6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06850">
        <property type="entry name" value="biotinyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.100:FF:000003">
        <property type="entry name" value="Acetyl-CoA carboxylase biotin carboxyl carrier protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001882">
        <property type="entry name" value="Biotin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050709">
        <property type="entry name" value="Biotin_Carboxyl_Carrier/Decarb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45266">
        <property type="entry name" value="OXALOACETATE DECARBOXYLASE ALPHA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45266:SF3">
        <property type="entry name" value="OXALOACETATE DECARBOXYLASE ALPHA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00188">
        <property type="entry name" value="BIOTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0092">Biotin</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="2">
        <location>
            <begin position="4"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0008689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="92" mass="9547" checksum="B22FEB8B40A207F5" modified="2023-09-13" version="1">MPIKEKASTTNMILSPMPGSVVSVDVKVGDVVAEGTAVATIEAMKMANVLRSVRAGVVKSVMVKPGDSVAGDELLIEFEDESKEAAKGGDKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNK9</accession>
    <name>A0A9P6MNK9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ER membrane protein complex subunit 10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">EMC10</name>
        <name evidence="3" type="ORF">BGZ80_004259</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002191">
        <property type="protein sequence ID" value="KAG0007764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNK9"/>
    <dbReference type="OrthoDB" id="1894652at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22209">
        <property type="entry name" value="EMC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39219">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39219:SF1">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21203">
        <property type="entry name" value="ECM10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040421955" evidence="2">
        <location>
            <begin position="21"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0007764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="305" mass="35226" checksum="18903CD1B4CB8B64" modified="2023-09-13" version="1">MKLSTYILALTLAASVQVLAEEVTLGVWHKLSDHESFEKRGEIRFDADEWHNQIQIKREQANAPPTSRSSKQNKQKQQQQQQPLQPFASYQNVQLNDAAIATLAEDFVLNVQAPVKFEEPEPEPTDRLVFEDGEVETDEEFEQRMDEWKMRQEEYEEMLQIKRTPGSYAFYQIKLTDESRGWEAMSSIKSCLLVASDFKEEITLHLDQDHRVFAFDYYTAVSKCENDHKNEYPLKSLDQFNSVKIDVATSEEGPKAHFVKAQAIKMDQTGKPEAEKTFLQKYWMYIVPVVLVMMLTGGEPEKTAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNY3</accession>
    <name>A0A9P6MNY3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_003361</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001885">
        <property type="protein sequence ID" value="KAG0008505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNY3"/>
    <dbReference type="OrthoDB" id="2416617at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027353">
        <property type="entry name" value="NET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038336">
        <property type="entry name" value="NET_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17035">
        <property type="entry name" value="BET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NET" evidence="2">
        <location>
            <begin position="237"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="327"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="396"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="333"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="343"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="358"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="412"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0008505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="466" mass="51192" checksum="C63139AD0A7E2FF1" modified="2023-09-13" version="1">MSVSAQTNSSVAPTFSISDFLVPALQTKVWEDWQSADDFTTFDPQTFSSDVSVLPFQLDLEGFIGNSSIWENDAIPEEQAYDELVFDLAPTAFDVPATVNVADLIVGPNSMASSAAVSPLDLAMSNDSTYQDLALANLYGFNDASEAFDSESDSDSEDEDSEEDDDQNEDEVKLDLQEIAKVAQEVVEEPTVVAVEPPSMAAESMGTITVEVVSEEDAVVMSSTKPEDPNKRRMEEVLATRINNDLGPEHMAGLFKILKGTSADQENEDEDEEMEVDLSSLDEATLVEVYQYVESCCMQTMGFIIAAEQRERAAELERQMLQRAYAERTPELSPSHSCASSNPPSPPHPSSHPPSPSKSHRSSHGSHKKRHGAIPYATMANFEMGDHLEQDSLWTSTASHPYKSSGRRKRSNTGTRTKMQKDVQYQHQQLQGYATGEAVVLRAADDSDQSNEMEYGEDAEIDIVGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MP48</accession>
    <name>A0A9P6MP48_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Peptidase S8/S53 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_003336</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001879">
        <property type="protein sequence ID" value="KAG0008526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MP48"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF66">
        <property type="entry name" value="SERIN ENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0720">Serine protease</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040374169" description="Peptidase S8/S53 domain-containing protein" evidence="6">
        <location>
            <begin position="19"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="7">
        <location>
            <begin position="138"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0008526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="254" mass="26995" checksum="D3A4010A1B3B4633" modified="2023-09-13" version="1" fragment="single">MKFTTILSALAAATLVSAGKFHDIGNSENVNIVPGAFIVEYHDGIKHSDARNALNSRKVDYKVRNEYNVFNGAAISVKSKHNGDDLASVPGVKNVWPVTLYSVPKIQKSKKKPTDPEVTSLHHMTGVDVVHSKLKLTGKGVKVGVIDSGIDYKHPAFAASGANEGCFARYGKKCRVAHGWDFVGDDYTGYNEPKPDSDPMDCGGHGSHVAGIIGGNALNVKVSPKPPQPFVGVAPEVTFGAYRVFGCDGSSGDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MP51</accession>
    <name>A0A9P6MP51_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_002985</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001766">
        <property type="protein sequence ID" value="KAG0008853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MP51"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="364"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="443"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="659"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="906"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="975"/>
            <end position="1031"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="26"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="214"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="240"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="279"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="381"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="453"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="479"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="505"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="671"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="717"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="745"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="768"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="794"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="821"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="906"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="986"/>
            <end position="1021"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0008853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1100" mass="120394" checksum="870DB00E6BD529C2" modified="2023-09-13" version="1">MSSSNQVISNATTMWTVGQQKSNTNSQSVPSDAVPSSSSSTARTNTNTHIAAPTITSKVSGAEEKPLEGVNAHSSRSKFLRAFGKFKNKHLSQKKANAATTGALSATCNNSITSDRTSSTTKSFVLPPIQFDREDSLGHTDSASMRSYTEPITPKENIEQLHDIDMEDSEASRSSYPNQDRPASSSLRIKLKNRVNTTLASIKSSSSLREKAKAQAASTSSSNSQSPVSPVSPQQPPSPDTTTTDPQQNNTMIRLAKPFWAFPRIRPEPSVHSKPMPWPSSASSDRPSSMVETSPQTKTIQNADLDAVMISPELGPSTQQANVEEVDSDEGSIDFIMRSDYDDYTQDAELPIKKRNKRAQAMKRFLLPQKATAEKDKGKSTENSQNTAETSHVIPQRNSKKRPKDQDSIEQRQGMEPNKMVKSNSEEPSEWRKAIMKSLHIGKGNQALRKTKGSPTSLQPSLESPVSATSAYTDILSPPESSEASQRDSGVYPSDQGSRSKRPESISSARSRSMATASHPGLLATTLPKPTNPITRRETLEMAMRRRRRSSAARSNLLDTENYLTVPRIPNQFDDDAASVHVTHTFTSFTLELADMQHANAVVNNSEIPGLFNFKRQPRLTMSSMNQMDTETEFKGFDSDGDAMSGYTGDADVSMEEIFVRPKTPQASRSGEGKEKGKSRESGSFDHSSRRKMSIRDADSDTLPELPTLPIRRDMNRSSTSSRISNNSTRAQENTGRESPRSQRRTGSSSSPSLSRKASRGHLAGSLSIDTSSAASARNPPTQTSVDEVASWKPRNTMNTKPTLTARTNGPSSSAHQRQPSSVLQQFQSQHQQQTSADTLLPNHLKNFSNASTLSASSGYSAQTLNGNVPLVFQPKEFNQNQDAEPTTPVDLKSMDFDTLLKTAEREQQKGQEERTLKKKKSFQFQNSRALKAQHHGLSSDRSNIENYSSGFYRSSNTSSSTKSALSALVASAPNLDELRTRGPDTNHNGYSNQQHSPPNSGRSHSSNGSKFGGLQVQTNRPLGPSHPRVPVSKSAITFDLAEGQAISNNGARNNPRSKRVMKKKTSVIKLSGNVQGRREDDGMIRVTVTPTVDLRQWRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MP92</accession>
    <name>A0A9P6MP92_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_003437</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001908">
        <property type="protein sequence ID" value="KAG0008444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MP92"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47679:SF2">
        <property type="entry name" value="C-TERMINAL OF ROC (COR) DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47679">
        <property type="entry name" value="PROTEIN TORNADO 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0008444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="545" mass="61929" checksum="2F0A0D8EA7F9536D" modified="2023-09-13" version="1" fragment="single">MEETQLFRLIGTADTVEIPVSHVGGQNIVYWVDIKQVFKDVEYVKNGKVAVNMLKDQIGNNIEPPRIKHLPDRVLDVVTSIPPSTISAAESNFQEYIVEKVDGLTVTSHEIKNMVAEALENQKLMQDRLALIQKKAEAILVQNYELLEYTIPRLFVVLPETPTPWDPATMVRTKFRLYFICECGEHTKVPRSTFPNHLHLAKHEGYVIKKPTEFFRKYGPFLMAMLHSIKIGTGIAGHVVPALANLKVVDVIDSTLSAVDSVTKEVIDGVDYSIKYLEENRTQIQMSNEVDIDGDEVALRNLDSYFTRVEGLEGVDLRQLGSYLKANSSDNLLGNLYRITTDKGHVKWVCIDHYRQAYKEREQQDFEKAVQVNGGSYDPQLGKVVISLESKIRAEEFFVALAKARHVDDLDITFDWECGRRDLEALEEALKKSRVSILRLDLLRFRTSLGRKLLATSTQYETLYHIVELPNTKRVHVVLPKELVKLSDFKPKGQLDLHKLSCEMIAESMEEREFETLVKALKTNSILITLNLRYNSIGSNGAQAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPA3</accession>
    <name>A0A9P6MPA3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">EXPERA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BGZ80_002873</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001730">
        <property type="protein sequence ID" value="KAG0008962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPA3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000247">
        <property type="term" value="F:C-8 sterol isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047750">
        <property type="term" value="F:cholestenol delta-isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004769">
        <property type="term" value="F:steroid Delta-isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016126">
        <property type="term" value="P:sterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007905">
        <property type="entry name" value="EBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033118">
        <property type="entry name" value="EXPERA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14207:SF0">
        <property type="entry name" value="3-BETA-HYDROXYSTEROID-DELTA(8),DELTA(7)-ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14207">
        <property type="entry name" value="STEROL ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05241">
        <property type="entry name" value="EBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51751">
        <property type="entry name" value="EXPERA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9 13 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="7" id="KW-0756">Sterol biosynthesis</keyword>
    <keyword evidence="10" id="KW-1207">Sterol metabolism</keyword>
    <keyword evidence="4 13 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 13 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="118"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="149"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="181"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="EXPERA" evidence="15">
        <location>
            <begin position="62"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="16">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0008962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="197" mass="22958" checksum="B610F23E62815086" modified="2023-09-13" version="1" fragment="single">MAATTRVSHPYYPVDLILDHYVPNTYTMKDTLTLLFSTFGAITVGSVLLSYQRRDSTIKGLGNQLTFLWFVMCGFIHFFLEGYFGIYHQTLAGDQFPLGQVWKEYSLSDSRYLSSDSFVLIMERITAFAWGPLAFYTAYAMYSRQPTRYVAQLILSLGQLYGCTLYYLTTMVEGSPHCDPHPYYYYFYFGFFNIFWM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPE6</accession>
    <name>A0A9P6MPE6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ras- protein Rab-4A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">RAB4A</name>
        <name evidence="2" type="ORF">BGZ80_002795</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001704">
        <property type="protein sequence ID" value="KAG0009051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPE6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001447">
        <property type="entry name" value="Ras-related protein Rab-1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050209">
        <property type="entry name" value="Rab_GTPases_membrane_traffic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47979">
        <property type="entry name" value="DRAB11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0009051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="187" mass="20767" checksum="AD83513CBE0AA527" modified="2023-09-13" version="1">MHDMIDHAYSISLSKTIKENATHTIGVEFGSRIVTIGKNQVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDISNRNSFMSISKWIADARKLAGADIALMLVGNKLDLEDREVTYLEAKMTFLETSALTGEGVEETFLKCGRAILTKIETGQVDPERPGSGIQYGDSSLRRIAQKSRPARQKSLCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPT2</accession>
    <name>A0A9P6MPT2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Signal recognition particle receptor subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BGZ80_002479</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SRP receptor beta subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001613">
        <property type="protein sequence ID" value="KAG0009348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPT2"/>
    <dbReference type="OrthoDB" id="41266at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043001">
        <property type="term" value="P:Golgi to plasma membrane protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034067">
        <property type="term" value="P:protein localization to Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04105">
        <property type="entry name" value="SR_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024156">
        <property type="entry name" value="Small_GTPase_ARF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019009">
        <property type="entry name" value="SRP_receptor_beta_su"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45909">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-RELATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45909:SF1">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-RELATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09439">
        <property type="entry name" value="SRPRB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0009348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="248" mass="27718" checksum="FB0EABA314804D84" modified="2023-09-13" version="1">MSSSALGGLIPQQLIIANNEYLTLLVFLALVALVGILVNFTIGTKRNSKNTILLTGLPFAGKTATYYLISHNKAVETVTSIKENETDVALTEGQKPIHLVDIPGHERLRFKFSEFMPIARAVVFVVDSSTVSRQTRLLAEYLYDILGDKFAQSERIPVLIACNKSDLLTSFKKERIQTLLEAEINKLRQTRTAALDTQDSEGNENVFLGFEGKDFSFEDLENDVEFIEYSAENKDIENIKDWMASVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQ60</accession>
    <name>A0A9P6MQ60_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_002907</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001743">
        <property type="protein sequence ID" value="KAG0008926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQ60"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0008926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="83" mass="9652" checksum="DB01FBB69274BB52" modified="2023-09-13" version="1" fragment="single">MTSLSSQESDGHPALPRTRTPRNHHRYSFKTRRGVTNPPPPDRMKLYEFKPYKERTDTTEGSTEDDKTESKRSRSNPMENSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQ84</accession>
    <name>A0A9P6MQ84_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Small nuclear ribonucleoprotein Sm D2</fullName>
            <shortName evidence="9">Sm-D2</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">snRNP core protein D2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">SNRPD2</name>
        <name evidence="11" type="ORF">BGZ80_002853</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytosol</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the snRNP core protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001725">
        <property type="protein sequence ID" value="KAG0008988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQ84"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030532">
        <property type="term" value="C:small nuclear ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027248">
        <property type="entry name" value="Sm_D2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12777">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN SM D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 9" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9 11" id="KW-0687">Ribonucleoprotein</keyword>
    <feature type="domain" description="Sm" evidence="10">
        <location>
            <begin position="19"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0008988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="62" mass="7311" checksum="95912EBAB924E13C" modified="2023-09-13" version="1" fragment="single">MTEEELRKLEEEEFNTGPLSVLQQSVKNHTQILISCRNNRKLLARVKAFDRHCNMVLENVKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQI7</accession>
    <name>A0A9P6MQI7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">CDK5 regulatory subunit associated protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">CDK5RAP1</name>
        <name evidence="12" type="ORF">BGZ80_001812</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the methylthiotransferase family. MiaB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001421">
        <property type="protein sequence ID" value="KAG0010077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQI7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035597">
        <property type="term" value="F:tRNA-2-methylthio-N(6)-dimethylallyladenosine(37) synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060255">
        <property type="term" value="P:regulation of macromolecule metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080090">
        <property type="term" value="P:regulation of primary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12160:FF:000003">
        <property type="entry name" value="CDK5 regulatory subunit-associated protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.30.20:FF:000003">
        <property type="entry name" value="CDK5 regulatory subunit-associated protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12160">
        <property type="entry name" value="Methylthiotransferase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="entry name" value="tm_1862 like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaA/NifB-like_rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005839">
        <property type="entry name" value="Methylthiotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020612">
        <property type="entry name" value="Methylthiotransferase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013848">
        <property type="entry name" value="Methylthiotransferase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038135">
        <property type="entry name" value="Methylthiotransferase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006463">
        <property type="entry name" value="MiaB_methiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002792">
        <property type="entry name" value="TRAM_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00089">
        <property type="entry name" value="MiaB/RimO family radical SAM methylthiotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43020">
        <property type="entry name" value="CDK5 REGULATORY SUBUNIT-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43020:SF2">
        <property type="entry name" value="MITOCHONDRIAL TRNA METHYLTHIOTRANSFERASE CDK5RAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00919">
        <property type="entry name" value="UPF0004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00273">
        <property type="entry name" value="(dimethylallyl)adenosine_tRNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01082">
        <property type="entry name" value="B12-binding_domain_containing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00413">
        <property type="entry name" value="CDK5RAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01061">
        <property type="entry name" value="methylthiotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51449">
        <property type="entry name" value="MTTASE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01278">
        <property type="entry name" value="MTTASE_RADICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50926">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="MTTase N-terminal" evidence="10">
        <location>
            <begin position="120"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="Radical SAM core" evidence="11">
        <location>
            <begin position="264"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="domain" description="TRAM" evidence="9">
        <location>
            <begin position="524"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="30"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="30"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0010077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="658" mass="72069" checksum="884BFF412AA6FB1D" modified="2023-09-13" version="1">MPPQLSLLVASLKASRGAAIRATRGVRALATTTNTLPPSPGQQHTSGSEEGGKNSATPPKGNTKSPKKTQHLVFGNRGPSFQDFLNSSTIKANNPKDANIATLDDIPYLSVKGRKLGAGAKYFVEVYGCQMNVNDTEILMSIMNTAGYVKAEDKSEADIVFLVTCAIRENAEARIWNRLEDLKRKRLGPLKNRAPLVGVLGCMAERLKDRLLDSDKMVDLVCGPDAYRSIPHLLSISENTQQGVANVMLSADETYADIVPVRIDPDSFSAHLSIMRGCNNMCSFCVVPFTRGNERSRAVESILEEVKQLSDQGIKEVTLLGQNVNSYRDTSEDGVQLSSGVGAELSNPGFNTIYKRKDGGMRFTELLDRVSLVDPEMRIRFTSPHPKDFPTALLHLMASRPNICSQIHMPAQSGSTTVLSRMRRGYSRDAYFELVDTIRSIVPGVALSSDFITGFCGETEADHEDTMDLMRRVEYEMAYMFMYSRREGTHAGRRLQDDVPEDVKLRRLQDIIQIFHKGAENRFRARVGQPAGECVLVEGRSRREKNRWVGRADGGFKVVFDDDLILPSIESSLTSSTTLGASAGRVPIKLGDYVQVVTTSATSTSFQGKALARTTLGEFSRYQSKISAGQPELGFRASSSTASPLVASLGLGSVEVQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQY0</accession>
    <name>A0A9P6MQY0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_002003</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001481">
        <property type="protein sequence ID" value="KAG0009843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQY0"/>
    <dbReference type="OrthoDB" id="2123952at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051615">
        <property type="entry name" value="Transcr_Regulatory_Elem"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313:SF81">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="25"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="88"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="730"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="816"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="902"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="94"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="122"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="163"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="734"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="745"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="820"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="905"/>
            <end position="914"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0009843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1034" mass="115403" checksum="E62287C06A2F7420" modified="2023-09-13" version="1">MFNSPMLLDFNSNNNQQKRSKITKACDNCRRRRVKCDGVPDGCGGCKAAKTQCVYTTSNTKRGPPKGYVEVIEDRLGKIENMLTSIVKKKKSVSKTSSSSPSSSDKAKPTSSSSAPNIPSHDDEESHGEEDEEEEDDDRASVCSNDLVKVKQQPPASPALRPTRSSTPQRNNRSGSVAMSPLGRHSPLVSRNRSLTSLFPFSHDNLANHFATEQDHSSVTNQDIAALTNMFDNLGSTSVRTTVPFPWLTPEQSRQYGRNHLQFSLQSLEPPLPALTRTFPPNISPDQTRQLLDSFFNRFNTFLPIIHRPTFMKQWEQQSCRICSNASSSSSEEIEAHQQHLNNPASPISPLLLNALLAVAAKVPSTGSRMTAEDRQHSGALSQGFFDAARLLLDDFMDVPRVSTVQALCLMSQYHHQGQWKATRSSSYLSMAIRMAHELGLHRDPESMANGPEADGLRYLWWSMFIMDHQFSAWLGLGLMMHGKESDVELPMDPTSSQQDLRGFVCMVRLVKILGSVLQHSYSTQSLPPQFGGHDSMVSYIEGSLTSWLSNLSPEMRWQNPLSVKRVSPGSPIRSPPSVQASLAEARRAVSLAKDAGEVYPAYLYIVYNTTLILLHRPYIVGAAGSPAAAQSNTICTGSGRAITDVAQGLDMEQCSYVVNRFSLYALLQAGVIHAMNAVYDKRGSQVAMDYYTRTLKILEGFLNCSSYSGGVSEGIKILEQFLATTSRAAAQEEDNRKSDHTEDVYQQQQETDAQPSRKKRQLEAGPIASQQTSATMHYAPLPQALMTPTLSMINASKPNASANGTLQAPYQYTYNQPTQQQQQQQQQQQQQQQQRPVDLKEQQKQQQLKIQQQHRLYQQMQSLGTDAVNKPTTAKAETLLEQQQLQQQQLLRQQLQRQQQRQQMEVEMKEQDANPHQQQQQPVLSSMAAPVIPSHRYAMQMLQQQQHGHPNMPMTMTAINMEAQQKMNQDQLSIGTMNPMVADNFEYDPTKFWVDFSDSSNGTLNPAQLHDSSAATINNRPMAENQFGGSLWM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MR05</accession>
    <name>A0A9P6MR05_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001508</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001343">
        <property type="protein sequence ID" value="KAG0010412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MR05"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040316495" evidence="1">
        <location>
            <begin position="19"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0010412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="116" mass="12934" checksum="F82A9752A570821C" modified="2023-09-13" version="1">MLFTKFFAPLALAAVVSAADWESVCTKGNEAIMISNNQYQTRICLSISLSAAKDKWGGGRSNCNKGTWEAYWNIASNGQTWLCYGKQSDCPYREAFLDEPLAKSRGYDKCWSISLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MS27</accession>
    <name>A0A9P6MS27_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Tetraspanin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_000542</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001111">
        <property type="protein sequence ID" value="KAG0011641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MS27"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018499">
        <property type="entry name" value="Tetraspanin/Peripherin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00335">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="81"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0011641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="203" mass="22291" checksum="94DE4FA2B173B23D" modified="2023-09-13" version="1">MANLRRQQYYYFFFLTIYILTGAGALILGNVWLSQAAAGGAPREAVISRQIEQAGTIIGGVVVGTAVFGVVGGAAPIKLKVILTSFIFMLIGAMLAELGLGGVIWFKTLRMRSLYQSQWPIWPDTLKIAFQDMTSLAGYGQCCGYTQFTGVVLSGACADPNQQFDGCEEKVSAFADGYLRKLNDEERYIRIRNKEGRTYTNVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSI4</accession>
    <name>A0A9P6MSI4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_000242</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001043">
        <property type="protein sequence ID" value="KAG0012052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSI4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031593">
        <property type="term" value="F:polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023238">
        <property type="entry name" value="FAM175"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31728">
        <property type="entry name" value="ABRAXAS FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31728:SF5">
        <property type="entry name" value="OS07G0540200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="157"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0012052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="196" mass="21947" checksum="79E4F6D91583A19D" modified="2023-09-13" version="1">MNPFAPRQGEPSPVSMALFTAKTNENRSTHDYDYTFWRVGDDEDAFESIPVHISNMIESPQEDYQSFQSNLAFSASRHNASLGIMNAIKSVQTTALVDGHEAMYRDSFEATKSLVKSVLASEQAVKDALKEIEQIKEQVENAKVAASLRKRGRLQKQEQTISQQQQQPHSHPRPHSQIARTSPFNSTAGSPPDLLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTL8</accession>
    <name>A0A9P6MTL8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BGZ80_011446</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the ZNF593/BUD20 C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000920">
        <property type="protein sequence ID" value="KAG0012889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTL8"/>
    <dbReference type="OrthoDB" id="24683at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043021">
        <property type="term" value="F:ribonucleoprotein complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000299">
        <property type="entry name" value="Zinc finger protein 593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051879">
        <property type="entry name" value="C2H2-ZF_Maturation_Protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003604">
        <property type="entry name" value="Matrin/U1-like-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022755">
        <property type="entry name" value="Znf_C2H2_jaz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46095">
        <property type="entry name" value="ZINC FINGER PROTEIN 593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46095:SF1">
        <property type="entry name" value="ZINC FINGER PROTEIN 593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12171">
        <property type="entry name" value="zf-C2H2_jaz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00451">
        <property type="entry name" value="ZnF_U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="59"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0012889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="133" mass="15340" checksum="98D69BEF64F097F0" modified="2023-09-13" version="1">MGRLRRSRVHKGIRDIQRKYRTKRYMRDIDQIHEDIQPENASKFEKPELDPELPGLGQFYCVPCAKHHINKESLQEHQKGKIHKKRVKLLKEEPYSQAEADAAAGLQRADTKAKKAKAEAMMDVTETNTTTSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUT0</accession>
    <name>A0A9P6MUT0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SWI/SNF and RSC complexes subunit Ssr4 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_010490</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000735">
        <property type="protein sequence ID" value="KAG0014348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUT0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051647">
        <property type="entry name" value="Mediator_comp_sub12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046464">
        <property type="entry name" value="SWI-SNF_Ssr4_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46007:SF8">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46007">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20497">
        <property type="entry name" value="SWI-SNF_Ssr4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SWI/SNF and RSC complexes subunit Ssr4 C-terminal" evidence="2">
        <location>
            <begin position="295"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="550"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="173"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="272"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="295"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0014348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="571" mass="63173" checksum="71E6A1B9EBE23479" modified="2023-09-13" version="1" fragment="single">MATRLPPELAGELYCRANIEPMIYNIMNPQMAIELLDKAWLMITQNQITFSFNYIDKPKEGSGFFLKVQPDEIIMPHDGYQYMDDEVSYGYQPDSRLVITERSQGFAHGDQYTHIVRRKYTLSQPGRDTLALLHYSKAELSRSVVVDGRRAKTPARQYPLKPIPGLTVPPPHQQQQQQQQQQQQQQQQPQQQFRPQQPQKMPPNPYAPSPVGAPPSSPQQPGGPYGRFPGVPTPVAGPPGQQPPQRLSSLNSGAYGNQRHDKKSSHKKHHQPQQPQLTPQQQQQLLAQQQAQAQEDAEEPSGDELDFLTARDVAIARYKRNHDYIAEVFSPYPTSRIIPPRPEYDKSIEFLKAQGAKHDVDLDALREEHDAKIKRFKEEAAVFYKGLEDLKQATTIQEVYAANGRVEAFKGMTVQPYLGLRQIQLPKDEATLTPELKPSRVKQPVELGNGMALDGNVPSLDNNGITTSLVENSGVGVVAPKSADQFATNGVPIAQVAAAVSAPMELDVPQEAPIQANNAPVISEDIEMAVNNPTTNDFVPVAATDIQTSAPAIGENPPPVVSAPEAHVEPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MV46</accession>
    <name>A0A9P6MV46_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_010749</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000783">
        <property type="protein sequence ID" value="KAG0013961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MV46"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="125"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="333"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="431"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="899"/>
            <end position="981"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="366"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="482"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="669"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="748"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="17"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="130"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="160"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="190"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="226"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="252"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="431"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="458"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="899"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="928"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="951"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="971"/>
            <end position="981"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0013961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="981" mass="109807" checksum="E567F9648CA6DCFA" modified="2023-09-13" version="1">MAQVRSHRVSVQHPGTPRSQSSLTSNSSFVRPRRINVNLPKHSTAAEAFHSQIAVTSVPSRNRVLEGRERYAELVLNHTMSEAILKMPNVATKPRSFEEIFEPEPLDHSNIKVICRLPAVAPTPHSNLKISMDIPSRSISSSPSFSNQRPGLDRGRSGQNTSNTSNSTSIIMTSESEKDELNAKRSSMNPLAATFTPTFPKPTLSDCATSDHSSDSRPKPSRHGTADSNESLVNGLGISSPSGELAPRQQKQRGLSVNTTAISPATLTRQDRPTYAESPPMTANSVATTMTTTTEFDLEEFRINLMRQISDNLETGLSRHFSKIASATSSIPLSPASQNQITESSNSIATSGSNASMNTSTEEVTIIQLKKLLRNTNAELERLKEKNQELREVNYKFEREHLEAAHQVARLQDFEPNQQFLLARIKELEASSSSSSDSALETSSMNGHRRTEHHSDINNNNNNNNNNNNNNNNNNTAQTQQIQKLMRDVAAVTSERDALKIRSWELEKKPFAHQDVRSTYLIDLENERNRLIEELSQKTVAMEDLWNKNEALTLRAKEYEKRVWELEGQVTTLESDCASLPQIRSELVDMEARAEAADALVEKLQDMEGQVALVKSLQERIHELETTNAELDHSNWDLSEKLNIANNQHALLTKEFESFRSKDKDDRRLEFLAARNRELETLLAEQTKISPDYKEEYNRVSSELEKLKIRMPQLEGQAKQVALLRSKTLQLEKQIKTMESLEPRLGEMQQLHERNLFLESELGELENLRAREMELEHELAEAKSKLIQLESSKTRMNSFSGLKQFQTRARSGSVAQHSAPLPFQNLTQQSLQQDESRNDIPAEDLMIKTVAGTPSSRLGQSSQSISSMDGILSPRSPKCEFPPATFMSASTPVTNMWPSGRSSMSMSNASQRMSTSSSTSTVMSSSSIGQFRSHQQEFSTPVSPEESADEEEKKELEALRSKEVTEEPDSFVNTGTAQEVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MV58</accession>
    <name>A0A9P6MV58_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_010701</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000775">
        <property type="protein sequence ID" value="KAG0014018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MV58"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0014018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="111" mass="12679" checksum="1DBBB67464B01FB5" modified="2023-09-13" version="1" fragment="single">MTSTSTETPTSPGLIQTLEDQVLELADHEAWLDAQIRELEFANNQDCQDDNRKLAQLLSEETATMKETTASQESGSNRRMAQRIEEELKNINIKYNVISNVLQVIYLFKMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVD9</accession>
    <name>A0A9P6MVD9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Vacuolar protein sorting-associated protein 26B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">VPS26B_2</name>
        <name evidence="4" type="ORF">BGZ80_010415</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VPS26 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000722">
        <property type="protein sequence ID" value="KAG0014480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVD9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.640:FF:000010">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.640:FF:000001">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 26A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028934">
        <property type="entry name" value="Vps26-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12233">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING 26 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03643">
        <property type="entry name" value="Vps26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0014480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="309" mass="36384" checksum="D5FDE2C4EC4E8A9E" modified="2023-09-13" version="1" fragment="single">SLFGLTVPVDVEIRFNGQDQRKQIEAKVDKDRKEKFPLYFDGETVAGKINIRVRDGKKVEHNGIKVEFVGSIELFYDRGNHYEFRTIQQELAMPGELRNTTTFDFEFKNVEKQYESYHGINVKLRYFVRVTVMRRLADVVKEQDIWVHSYVMPADGNNSIKMEVGIEDCLHIEFEYNKSRYHLKDVIVGKIYFLLVRIKIKHMELSIIRRETTGAPPNQYNESETITKFEIMDGAPVRGETIPIRLFLGGFELTPTFRDVNMKFSARYYLNLVLVDEENRRYFKQQEITIFRRQVDDEVVDGQGMLQHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVH2</accession>
    <name>A0A9P6MVH2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">N-alpha-acetyltransferase 16, NatA auxiliary subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">NAA16_2</name>
        <name evidence="7" type="ORF">BGZ80_010506</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000739">
        <property type="protein sequence ID" value="KAG0014323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031415">
        <property type="term" value="C:NatA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.1040:FF:000003">
        <property type="entry name" value="N-terminal acetyltransferase A, auxiliary subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.1010:FF:000002">
        <property type="entry name" value="N-terminal acetyltransferase catalytic subunit (NAT1)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.1010">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.1040">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.600">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021183">
        <property type="entry name" value="NatA_aux_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021860">
        <property type="entry name" value="Peptidase_S12_Pab87-rel_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22767:SF2">
        <property type="entry name" value="N(ALPHA)-ACETYLTRANSFERASE 15_16, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22767">
        <property type="entry name" value="N-TERMINAL ACETYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11954">
        <property type="entry name" value="DUF3471"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12569">
        <property type="entry name" value="NatA_aux_su"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="76"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase-related" evidence="5">
        <location>
            <begin position="838"/>
            <end position="1163"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S12 Pab87-related C-terminal" evidence="6">
        <location>
            <begin position="1213"/>
            <end position="1303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="577"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="600"/>
            <end position="627"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF11954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0014323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1310" mass="148793" checksum="33A3840B6DDBCB44" modified="2023-09-13" version="1">MRELPQKEANLFKQILRCYETKEYKKGLKGAEQILKKFPEHGETLALKGLFCNHLDKKEEAYEFVRKGLRLDLKSHVCWHVFGLLHRSDRNYEEALKCYSQALRIDKENLQIMRDYSLLQIHTRNYEGFADTLHQLLELKPQNRQFWIGLAIAYHMMGKPDLGIKVLAAFEETLKDEIPAKPDYEHSEMLLYHNSLIQETGDIQAALDHLETLEKHVCDKKAIKEKRAEYLLALGRHEEAEAAYRILIAHNSDNFSYFDGLRKSVGLGNEDLSADDQVKVLDLLKSLQENYPRSNAAKRLPLRYATGDAFVKVADEYLRSMLRKGVPSLFVNIKTLYANNEKEEAIEKLALGYLAALDKSKSFDNSDSAVEPPTALLWTLYFLAQHFDFQRKSGQALSYINRAIEHTPTLVELYMTKGRILKHAGDLVGAMDAVNEARELDLQDRFINSKCTKYMARAGKMNEAEKTVVLFARADLADPLNDLVEMQAMWFSLECGESQLRQGHIGPALKRFHQVEKHFNDFTEDQFDFHMYCLRKMTLRAYVSLLKLEDQLRSHQYYVRAVEGAVRCYVQLFDKPESDDSEATEGMTEAEKKKFRNKQRKAELKAQKETEEKKAQAAQEILKKGGKVDEDPDGLKYTKAEDPIGEALKLLKPLQEQAAERIETHLMGFDLYIRKNKLLLALKALLKSHKIDANNSVLHEQLVRFALAVRKAGNSVKPAVKAVIDKHWDTLYQGKGDDLASFTASFIEKNKDLGSVPHLISAAIAVYLINPDEKSKAEDIVFLMASDKYVKTRSYENCIFARKTLKSWRSSRFKEFSAKAAEWYPKSPEFRDGLEKCRIQCGIPGMSVAILHKGELVLAEGFGKRNEKDPFTAETLAPIGSLTKSFTATTIGELVAEGKLDWDKTPVNKYLPEFELKDPVLTSQLTLVDLLSHRTGLPRETELSWFLSAETRSNLIKRLKHVEMPSKLSSKYLYSNAMYAVAGEAAANVAGATYEEIVRKKVIEPLSLVNSGFSPVEMEKRSSNHSMPYSAASLQDAQNGLFKLEDIGDICKSMAPAGDMFSNVLDMVRWGKVIMNAGEIDGKQVLSKENVQETLTPHTIIACPRRTPEFAPALTYGLGWDLDSYKGHTFYGHDGAVSGFRSRLEIFPDADLVIAQLMNVTNSELFAQGFSRYISDEILNLPKTQDWIINSIKETESRYDLMESMTKSTIPERIQNKPASQELRAYVGEYTNLIHGDVSITVGKDEITGEETLFYKTGCLDGKLSHYHFDSFIYEAKYLEILSSDIITFRGAKDGKVESLELMADEYKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVP2</accession>
    <name>A0A9P6MVP2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Decapping enzyme dcp1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_009870</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DCP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000630">
        <property type="protein sequence ID" value="KAG0015424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVP2"/>
    <dbReference type="OrthoDB" id="440673at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008047">
        <property type="term" value="F:enzyme activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000290">
        <property type="term" value="P:deadenylation-dependent decapping of nuclear-transcribed mRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031087">
        <property type="term" value="P:deadenylation-independent decapping of nuclear-transcribed mRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13182">
        <property type="entry name" value="EVH1-like_Dcp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010334">
        <property type="entry name" value="Dcp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16290:SF0">
        <property type="entry name" value="DECAPPING PROTEIN 1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16290">
        <property type="entry name" value="TRANSCRIPTION FACTOR SMIF DECAPPING ENZYME DCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06058">
        <property type="entry name" value="DCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="129"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="198"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="250"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="137"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="200"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="214"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="272"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="317"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0015424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="488" mass="52478" checksum="5D4328DB7BC624A8" modified="2023-09-13" version="1">MNKAARKAVNLSVLQRHDPHISDIIDSSSHVVVYKFDEDSQTWTKKNVEGTMFVFKRSTAPYYGFFIMNRLGLENLMADLTGDMALQLTSDYIIYRAGEDIHGIWIFETTDRDRIAAKLQECCKKAMEESQDLIKPSSPSAATTMHQSSPQRSTHTPSNPTPTDSAATDPLTRMLTEAMSRARVSETSGAPLVSHALQQAPSANASAPSSSSAVQKTVQSPPANQSQVNGSSSKSDIPSFLLAIISKEEEQPAVSVEESSSLRQHDPKDAESTQSKLLSSLTGSGKTSPSLDRQSSRHSGPPLSAEFLPPSVMPSGLYSNNSRPNGAQGNQAVIQHQSPSMAAAMLNRSNGVPAHASPLQTPAFAYSPGMMPSPLAMPPMQGGPMMRPTPPPPLPFQHHPMGPSMGMPPPPPPPQPAMLGASFPADAMHAAMGAVGFMQQQQRGFVSHGSEVLSKAEFSQQFMALVQNDPQFMDVLYSNYEAVIARRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVW1</accession>
    <name>A0A9P6MVW1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_010078</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000664">
        <property type="protein sequence ID" value="KAG0015053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVW1"/>
    <dbReference type="OrthoDB" id="2370248at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="443"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0015053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="557" mass="63399" checksum="345F72663E3BE2DC" modified="2023-09-13" version="1">MAERPIPSPLGSLPGNEHLVVILGASQSGKTTFTETTKQYALISGTNENPTVLEAVRTEDILTRFPNYHVEDHEKNPETPKIIRPCYCPCESDFILNCEDEYDYEEAIDERGQHLKLNYIDQIDQGSEPASFALLDTPGVTGVAPDGHIEPNLSRVLSISKAIASRNARNARNGISLVLIAVSTSIPLTREFTYALDCCIGTFSGLNSVFAFLHTKIKYENLYPGSSNFLEFQKRRTELQKIIGRPIPEFYIDCDIDHSKRPFRACITYNVIEKILQTATFNQPVMIALDVVNKTPRMKQIDKIAAVTYEKTLEARSDAIRTLNYNIDVNFSQAIEVLSNISKVESKLRTRRNDLNTYQSGNLELLYEDRYDGGQKLGEPEICTMELPVQKHTIDKVDIFHKGIRIEEVTVSGGEGEKSWRAEIPRIPIHAGTFQVRIYCKKVTKYCEEIEQAEFDIKSLEEEVVQLKVSVAHLEESIQSSYSKRRVELGWRNFRIHLIEWLTKDSLPRDTFQALVENEAYTQPTIEAFRMAMEEVYFGMFRDNGLVTEDNRSNILS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVY4</accession>
    <name>A0A9P6MVY4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_010382</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000717">
        <property type="protein sequence ID" value="KAG0014528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVY4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="29"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0014528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="347" mass="40399" checksum="045785D2C1EB5CDC" modified="2023-09-13" version="1">MHVEQKVIERILERCRRLRVLKLIRVNYIVQHQQQLGQEQEQEQELQQHLQQQQQQQQVLCFNRASFYTTVAKSCPMLKLFHLSMFDEHMGIEDAQNLIRTFYPGVQLESSVNDEQEHHNAEQTISRPFLDTVSVLDKDINRDTSHILFAPLRDPSFDKIITTLESSRPRARKRLHSHAQRDQIQGLGLSWTTDAANDVCIQELEGRAECGERENDVWIHFNLTWTTTKLEMKDIDWMARYPRKAFGSWLKSKLKTKSEQGLNQAANEFDDHDKKGLVDSIVYAGSEENLEKCQEHISQGMGHMGCLPMLDRLKLQVRLMHKGDIVISTQYLPAMIASVRPDVEFFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWG5</accession>
    <name>A0A9P6MWG5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HCP-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_009306</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000544">
        <property type="protein sequence ID" value="KAG0016304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWG5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="138"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0016304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="300" mass="33498" checksum="4D1B9D60F108106D" modified="2023-09-13" version="1">MSTPGPQQSLLQGFRPVYNTNTFTPSPLPSEPVCIEPHFISQTGEYIVLWDEVLVAFKNASHIPDLPNSSTSTNSSVNPLSYPQVESLINSEPSNPLPASSTLLTADGNLNLGDDFYNHTQSELSLSQQQTFEIQPQEFHNPQPPQQQQQQLGQEFQPSSSPQEYGSYAVPQVPLEPGSKTNPQYTAFSEYFLGLGYLEGNVVSQDHYKAMDMFRKAAKQGNPETQCELALLYYKGNGVPKDSSKALKWFFKAAIQNNGRAKAYFDYMYYQVYLGDSYGQNNLGVAYLDPKHNSSTVRHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWR4</accession>
    <name>A0A9P6MWR4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">phenylalanine 4-monooxygenase</fullName>
            <ecNumber evidence="3">1.14.16.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_009241</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.16.1" evidence="3"/>
    <dbReference type="EMBL" id="JAAAID010000535">
        <property type="protein sequence ID" value="KAG0016416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWR4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004505">
        <property type="term" value="F:phenylalanine 4-monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004664">
        <property type="term" value="F:prephenate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009094">
        <property type="term" value="P:L-phenylalanine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04905">
        <property type="entry name" value="ACT_CM-PDT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.800.10">
        <property type="entry name" value="Aromatic amino acid hydroxylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001273">
        <property type="entry name" value="ArAA_hydroxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036951">
        <property type="entry name" value="ArAA_hydroxylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036329">
        <property type="entry name" value="Aro-AA_hydroxylase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019774">
        <property type="entry name" value="Aromatic-AA_hydroxylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018528">
        <property type="entry name" value="Preph_deHydtase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11473">
        <property type="entry name" value="AROMATIC AMINO ACID HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11473:SF24">
        <property type="entry name" value="PHENYLALANINE-4-HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00351">
        <property type="entry name" value="Biopterin_H"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="ACT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56534">
        <property type="entry name" value="Aromatic aminoacid monoxygenases, catalytic and oligomerization domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51410">
        <property type="entry name" value="BH4_AAA_HYDROXYL_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00858">
        <property type="entry name" value="PREPHENATE_DEHYDR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0408">Iron</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACT" evidence="10">
        <location>
            <begin position="22"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="Biopterin-dependent aromatic amino acid hydroxylase family profile" evidence="9">
        <location>
            <begin position="91"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="Biopterin-dependent aromatic amino acid hydroxylase family profile" evidence="9">
        <location>
            <begin position="183"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="243"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="283"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601273-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0016416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="406" mass="45655" checksum="645D7BA2C9604769" modified="2023-09-13" version="1">MISASHDLLKCPDNVVAPVKATIQFSISDKAGSLDDCLATIESMQISLTRIESRPSKISEWDYDFTVDINAVNFEQVSQVVKSLESFAKQVQIINNAKVPDSTPWFPRTLTDLDPITKKASKIGEGLASDSPGANDAAYCARRAEITKNADTYKTGRPIPFVNYSRVEIETWAVIYNKLTKIVSKFLKSRTGFTLRPIKGIVPSRYFLNGLAFRVFHATQYIRHHTKPLYSNEPDICHELLGHAPLFADPDFADLSQEIGLASLGASYRDMKRLTAIYWFTVEFGLCRQGDQIRAYGGGLLSSFGELEYCLSDKPEIRPFEPAKVAQQKFPFSEYQPVYFVTESFKDAKMRVREFTKSLSRPFSVRYNANTESIEILDSKEKIIRCAQSTDIPTLAQNLESLAQSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MX62</accession>
    <name>A0A9P6MX62_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">PNPLA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_009364</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000553">
        <property type="protein sequence ID" value="KAG0016214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MX62"/>
    <dbReference type="OrthoDB" id="10049244at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006641">
        <property type="term" value="P:triglyceride metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050301">
        <property type="entry name" value="NTE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021771">
        <property type="entry name" value="Triacylglycerol_lipase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226">
        <property type="entry name" value="NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226:SF10">
        <property type="entry name" value="TRIACYLGLYCEROL LIPASE 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11815">
        <property type="entry name" value="DUF3336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 4" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="3 4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="6">
        <location>
            <begin position="359"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="20"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="157"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="821"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="935"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="4">
        <location>
            <begin position="390"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="39"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="100"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="169"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="825"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="898"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="946"/>
            <end position="963"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="392"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0016214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="977" mass="108775" checksum="0AEE24342064372A" modified="2023-09-13" version="1">MSRTSPPVIDEDFDLCISETNLPFPYSDHCSTGPPSLYEFDEDEGGEEGDDGDEEYEEREEDREEDHDSEETRDESLQDNDSDEIPSLTLSRLRTDSYDRSTSIDTPNDISHQLRSRLEHIQENDRSGVAMASPSDSALKISRPRYSRRSYSYESNGEWNVEEQEENSNHSQPTQDEQQPPENSLISTVTSTVSSVAYAVGKHWSKKIYESLLRSRDPKAYYTHLLEAATNYEQWSEAAVVLDRLQGKDKWKNDPKSPHYDYEMLQERLSQLATARASGDLGQMIFLLRTSLSRNIGNVGQRKLYAETIIGTKRLIEDYNSEVIRQLNIICDTESDDFSMAAKLEFFTHTRQAFGRTALLLSGGATMGLMHIGVIKTLHENNLLPRIISGSSCGSIIAAILCTRTDDEIPSMLQFDRFNFNVFHTLEETGDYLARLIHFLRNGALFDAQVLKAALKENIGDITFQEAYNRTRRILNITVSTSATFEMPRLLNYLTAPNVLIWSAVATSCAAPFIYNSAPLIAKDRNGEEVQWNPSRYHWIDGSVENDLPMNKLSELFNVNHFIVCQVNPYIVPFLQNAIARSPANRVLDWVLFQMRSELQHRMNQLSILGVMPELIHKVQSIMSQQYYGDITIVPSISAEDYLNIVSNPNVDFLEHATLKGERATWPKISIIKNHCSIEHCLDDILYRLRLRRFQAISRMPATLSKTPNENPDCHQKQVIGVTATSSLGPASLGNPKTRNSISTIFEPAGRSNSSPASPTATAMANLMMSQSTKLGECLVPDQGTNGLLIQTTSPTDLRIPMPNTVDTEHSNGVASIIKRMPFVHQSQNGSTKSSGPRPSFKRANSSGAQLSSPLTTTSSINGSKTPAISRHRNSISSTFEYRPRLENGYTSNTMENSSSRRSSSSSVSSTHSSVSSSASSVTVVDSCSAKGAHILNSNGFDKKATTVNGSVSSSNVSNGNGTRSKRPKRIQMSSLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MX98</accession>
    <name>A0A9P6MX98_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_009393</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000559">
        <property type="protein sequence ID" value="KAG0016155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MX98"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0016155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="236" mass="27356" checksum="DFBA8D52C73A261F" modified="2023-09-13" version="1">MAIFELWNTLKKKFEPGLAKGDLDTNCTYSVDLLACLFMEIRCIIFYQDGQQAFEKNPTYQERLDFSEKTVESAQIVWRPLENDIRNGRCPSKKEEKEFSKDFRKDFTLDSKDKQAMVDYPSQQGWRVILAPLKANVTIGKSCGDSDVVVARIVEEYARDSNVHRRNPTANDFKPSPSVFTCLTQKPVKKLLWNQESRNKRRSTMEDHVRRDKNYQTSNRSRTVEPPRGGDEDNAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXC2</accession>
    <name>A0A9P6MXC2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_008327</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000448">
        <property type="protein sequence ID" value="KAG0017381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXC2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045072">
        <property type="entry name" value="MKRN-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041367">
        <property type="entry name" value="Znf-CCCH_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11224:SF10">
        <property type="entry name" value="IP09428P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11224">
        <property type="entry name" value="MAKORIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18044">
        <property type="entry name" value="zf-CCCH_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="88"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="117"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="88"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="117"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="248"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="391"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="585"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="248"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="263"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="395"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="440"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="601"/>
            <end position="615"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0017381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="658" mass="71742" checksum="F9C2D6E7E41BC976" modified="2023-09-13" version="1">MDSPANPHTHIQGLSQDSPQGFDPHRWSDPNKGPQIEMSHIASPPLTPSGVLARSNVKRPPLWPVDRTPTMPFPRQAPTPSQSSKASNLQHIPCKFFKSGACTAGKNCLFSHSRDPPSENFVCKYFLKGNCKFGAKCSLSHSFLGSDRKTSALLSSSSLGRSRLERRASSGAILNNNLWPSEPMSPPYGSSLPQQTIQLNNNNVEFTMGRSTSQQGLLKPALNSSSSENMRSALYMNSLPQEIVNNRSPFSEGNSSSPEIVISGSNQSNNSSNGGGINLNNERATTNSFDLLENRVRQHLAAPLPIRQRSLPDIFRLTPLSHDGGAMPSSPFYQPGNKGLFLSVSCESDTHPSSPSRLHSIPEFHDLCSSYGAGSGNGEALQRRSSFAGCGMQREDEDEYIDSDDDSSLDQGFLPSSLNDLLTTHERQRRQSRQEDVDLRSNTLPSPASGSLKDTKEEDEARIIFGNTGDSGLQPQCTFTEYDQHGVTNGDVSISPFAVFIPGRGSISSYNPQGPSSFEEEDRYDISDRRGSHFKERGSSPDPFCPFPQDASETHFAMDDDILGASDAGNNYNYRSFQSSRFAPFDDDPTSMLSGEPSRAVGSNSGMQKQRSQYQTHNGTMTPVSFIAQDDAGIDFSSLSISERTFIKNSTSSQQSLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXC3</accession>
    <name>A0A9P6MXC3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Low temperature viability protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_008315</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LTV1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000447">
        <property type="protein sequence ID" value="KAG0017391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXC3"/>
    <dbReference type="OrthoDB" id="5852896at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030688">
        <property type="term" value="C:preribosome, small subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000056">
        <property type="term" value="P:ribosomal small subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007307">
        <property type="entry name" value="Ltv1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21531">
        <property type="entry name" value="LOW-TEMPERATURE VIABILITY PROTEIN LTV1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21531:SF0">
        <property type="entry name" value="PROTEIN LTV1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04180">
        <property type="entry name" value="LTV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="176"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="254"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="300"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="520"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="254"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="522"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="535"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="558"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="578"/>
            <end position="588"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0017391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="616" mass="69453" checksum="220CCDD2570E50FD" modified="2023-09-13" version="1">MGKKQFIDRKNARHFHLVHRSQRDPLSRDESAPQRVLKEVIPANLIGKVRVPNDDLDNDLFDDDDQDIFGDLGEDDGINYGTYDRAIEEVELLEAPTIQKKKKSSTKDETKIGEAALMGLVGDEFNDGSYDYTQHMKEIGRASDAVFVAAPKTVAQERKAAQSRGIQFTDASAAEEMAKEDQHKQATSSKSKKGLSLPSEVLPSREELDFDDVYQSAVPIGLQPDMPFDIRQTLEALEDEAFVDGELDESFFDQLDGEGGDFDFGDEEYDDYSDEEEEEEGAGGWEADFKKFKKAQKYASDNESFEGSDDGHSQTSRTSRRPGGASASTFSMSSSAMFRNENLTLLDERFDKIEREYEEDSLDEDEEPHDLKAEELRKDFDSILDDFLDKYEIVGSKMVPRLEGATSENKLSTIRNALLVDEGEEEKSLATTVGGTRRPKKNLDEDMATELQTDFRSRAEKLRDSWDVQTILSTYSNLDNHPGMIKEQPRRRIHIDPKTGMPVVTEKLSKKALQRRKEIEDAAAAAAAAENGGNSDDENNSDEEDFEEEEPENLGAKRNKEETKEEKKARKDAIKAEKRNRRETKKATKAAFASEKVRQEKVMKNVKKGQGVTHLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXX7</accession>
    <name>A0A9P6MXX7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Short-chain dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_007964</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000419">
        <property type="protein sequence ID" value="KAG0017733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXX7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05327">
        <property type="entry name" value="retinol-DH_like_SDR_c_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022234">
        <property type="entry name" value="DUF3759"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157:SF31">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12585">
        <property type="entry name" value="DUF3759"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0017733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="422" mass="46605" checksum="7AC5CCF6F69370B9" modified="2023-09-13" version="1">MLDCIYDIDYWKTYVQSSNFSLDQIPDLTSKVAIVTGANVGLGFETALELARNGAHVFLACRNKTKALLAIEKIERELAETAPHLYPKLDFLFLDLADLRSVARSANAFLAKGLRLDILVNNAGIGLIPPTLSKDGVELVFAINHLGHFLFTQLLLPKLIESQPSRIVCVSSMGHDLALPQGGIQFGTLSLADEEPPIVNYNRSKLANILYVKALARRLTAAGHDRVYVNAVHPGFCMTDIDVNVGNAVGYVAAQVMLKTRELLGRPAADGALTQLYCATSPQIEEKNLSGRYFVPDGHELRPGPFAMDTDLQERLYKYSEDFMVKRGLLSNHEDVYGGKTHHSKLSHEAIAGAASYEAMKEYQKNQESGHHKLTKEAFAGLAGAEADKLFETKGLSHLDRERVRRQTEENAGRIHDQIYGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYA7</accession>
    <name>A0A9P6MYA7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">T-complex protein 1 subunit delta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">CCT4_2</name>
        <name evidence="6" type="ORF">BGZ80_008511</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Molecular chaperone; assists the folding of proteins upon ATP hydrolysis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Component of the T-complex protein 1 (TCP1) complex.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000463">
        <property type="protein sequence ID" value="KAG0017227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYA7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0017227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="146" mass="15899" checksum="FCDBE8D62DE99329" modified="2023-09-13" version="1" fragment="single">NSLVLEEAERSLHDALCVIRCLVKKKYLIAGGGAPEIEVSLRLQEYAKTLRGMEAHCFQAFAEALEVIPITLAENAGLNPIAIVTELRNRHAQGETTAGINVRKGAITNILDENVIQPLLVSTSALELAAETVKMLLKIDDLVQTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYN5</accession>
    <name>A0A9P6MYN5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_008209</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000439">
        <property type="protein sequence ID" value="KAG0017501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000583">
        <property type="entry name" value="MAP3K epsilon protein kinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050629">
        <property type="entry name" value="STE20/SPS1-PAK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48012:SF26">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE DDB_G0283821-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48012">
        <property type="entry name" value="STERILE20-LIKE KINASE, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00185">
        <property type="entry name" value="ARM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="1"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1049"/>
            <end position="1106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1197"/>
            <end position="1230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1354"/>
            <end position="1494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1515"/>
            <end position="1557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1197"/>
            <end position="1207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1367"/>
            <end position="1432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1433"/>
            <end position="1445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1460"/>
            <end position="1470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1471"/>
            <end position="1482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1515"/>
            <end position="1535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="1546"/>
            <end position="1557"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0017501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1557" mass="173460" checksum="EB76B01B1AE7F714" modified="2023-09-13" version="1">MYIAQVLDGLVYLHDQGVIHRDIKGANILATKDGLVKLADFGVATLSNDISDMSVAGTPYWSKDLISRVAFISAPKDGDVSVGCTVIELLDGEPPYHDLPPMGALYRIVQDDHPPIPESVSVASGSQRSREKAIPAYEEAVKDVKQWNEALNGSSISTNRNSGNFRRSLGEKNGRSWEHGVPAITDIFHAPKPQGRAPAMAEPPQFRLQINNANNVTAAKNNNYEPETDADNWDDDFADGISSFQLAAREFLDQDDEGPKTIRAAPETLAHLADNSENDIDEDDFEDDDQELQLKIRVKPLGGKTKSTSKQQETIVKAGGSLAARAKNVGSYVPIDLVRSRSAPGQLALEPLPINDEFQNYREDEDDDYSDLLEGVERQGAMYQDEGLTLQTRLSNQSWYGNDAGSDEEDPFAEVDEGFDEIDLEANIAREKHAKICENISKQFRLLETQQAGRELEEVCDRLISLLTENPNIRGPMIANHGAIPLLDLIENSKPHTLIQKLLNILNLVIRKDFALQESLCLVGAIPVVIRYTSKKYSKNIQFAAAVFIQQICHTNPLTLQMFISCRGLGVLIDFLQGNYTTQKDLVWIAIDGIHSVFNLQSMTPRNDFCRLLAKQGLLDPLSTTLYNTIHDPQGASYTEKIVQVLLIFSQGDSPVKELLATRQIVHRMLSSLQNLPIELCVVMLKCIKNISMNSNTLDVLQNANAIHTLVQVLGERTGRFATDISNHVLTTLFNLCRINKSRQQEAAQAGIIPHLQQIAESSSPLKQFALPILCDMAHAGRACRNILWNNDCLPSYLRIFKDPYWQVNAMDAVLVWLQDETADVEQALLQPSSLNMFVQAFSTAKANSFENILEPLYKIIRLSPDIARGIAVPALFHRLLDRLAHPKAVVRLNLLRILRAIFDVHPERIQLVVRYGIAGVVNRIAKEDSAVLVKELAREILVAFEESDSEAVLSGDEKDRGVNGYDSFASTGDFFGLGPMKNLADTIKMEGKDLSEEKMPSQQHTLFGKFKDREPDLDPHHVDDLFQQKVNNLDINTGLDYRTSSHQRGFGLEGNGEGSSAQLRHRLVPPRSLNDEEGDSSGSEEHFVTTRPWIDGTDPSMSTVKQEKHVTLDADLDLEDNEPRTIKVSRPFSHQKSKSLSEILIEERKQLRKPEGVTNDMTESMILRSELPKIRLELLDIEHFPAWNRRDLEAEYENDDDNDSDEVTATRGIGKAGRGHVRPSWSESHQELRMTRLQGTTNEPDLSIEEQNNMMRGFQGPRRRLSMDDKVRSTISNNAGSIRRSSGSNSSEPTVRYRVTPFSSISSPDFYGNIQIKRQPPSLASIVGWNTAPGATVRTEEVIKVPSSPGLVLAKRQEYDDTLNFSDDDDDDDDDDGDKGEEEEIDDDEAGDEDGGDNNDDDNDGGDSNDDDDDDEEDEDTYQSASEDDYENQTIKASVITLHSSAHGAHGIRYGGTNDLDDNAFDDDDDKKTHPNLDRSPGRGNNHSTNYGGYLMEEGEIDWDLEEVRKGYEPPATVKKTTTTIVTSPLTSPLTSPPTSPTSQLRRRTSHRKSPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYT7</accession>
    <name>A0A9P6MYT7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_006900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000344">
        <property type="protein sequence ID" value="KAG0018656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYT7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031380">
        <property type="term" value="C:nuclear RNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031048">
        <property type="term" value="P:regulatory ncRNA-mediated heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF445">
        <property type="entry name" value="NFX1-TYPE ZINC FINGER-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="3">
        <location>
            <begin position="635"/>
            <end position="1016"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase-like C-terminal" evidence="4">
        <location>
            <begin position="1033"/>
            <end position="1163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="306"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1175"/>
            <end position="1199"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="918"/>
            <end position="945"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0018656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1199" mass="136062" checksum="36DBB7CAF299487C" modified="2023-09-13" version="1" fragment="single">MKGIISQETGRGRGNGRGRHHAYNRRRGVSQVIAAKRPPNIQITGEGTDDIIVAAPADESLRNVAEVFLRKGESTATVDFANQGQIRLFIHSCLLNLSNHHDFDTSNLLARLSSKVGCEVLSKIIRTPMGIRHTEDKDTLSFQYVILPLIGVLTRERVSQSMMSSEIDRIYSTVYLHHEVFMERVLLCIRQLRDKGFFRDASVSALKVIRLEPFTCQVNSFRFALLAIVRLIYQLLKRIDKARTELVSVVDNIAIHHESIAVMDANSPQELFAGELLAIEVARLQRIVTDSQYSSLGYTHVEALPTEHSQDFDPPGDISPKGPRNDNDKSEISEISLIPTMNELTCSRKPFLPSNGIQDAPHFLPPGWKRHLDIHFRLYREDLINSLRSGLQAFTRALKTVGYDNHDILSNPWELKKYHDNNTSLNFYGSVRFLSMDFERPSKGSIMIGFPQPLQIRGSRYGRRAEFWEKAKGRLMEKSLAFLACASKGNVQAHLVVVTKRNIRDLAKDGDTAFIQVSLTNPRLYADMLDPTLSNVGKWLLFETFGGFFESYRPVLAALKSCVPGSLPFGKYIAPTNEEERQNGLKAIDPPICTQAPEFKYDLSVLLKNRKCFLDTHDQESIARAIKALQVGSPLDDTQAKALVETLCREVALISGPPGTGKTKIGIDLMKVLMSNKSSMGGGPILCICYTNHALDQFLEHLLNENVTDIVRLGAQSKSERLQDCALASKEKNVRKSSSVKDTIIQCKEEWKLLSSEIKNLEKDIKSDRISWSYVGAVCNPNQYRQFEHDTLELDPLIICDEDPNDDELDVEGDDFTTVRSNKRMAKDNYDRWVQGLDIEELERWNNWILSFKDREEIQQDHNIFSVLSDGVEEMQEDEHLYHIPDQDRPLELLDGDIWEMSMTERKRLTESWRIRIRRSMADKMEELLNLAEQVSQKKNEAFDNVRREVLQKASVIGMTTNGAAKYQALLKSVSPSIILCEEAGEVLESHILSALSDSTQHLILIGDHLQLRPSVETYMLSSESKNGDRYKLDMSLFERLVTRTTNPFPMSSLTIQRRMRPEISSLIRNTLYKDLEDGGKVLEYPSVCGMGQNLFFMDHAHPEDRKEKFGIQSFANTFEIKMVEALARHLIKNGYNKQGDIAVLTPYLGQLIKLRDALRNNFILTIDERDQLELSKKSETMEQDESDENGVAATATKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZ68</accession>
    <name>A0A9P6MZ68_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transposase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_005964</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000294">
        <property type="protein sequence ID" value="KAG0019345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZ68"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0019345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="151" mass="17688" checksum="2E70339BD67A7839" modified="2023-09-13" version="1">MEVAKRVGMTIATTMRRVRTYRDDDEKRLLTRKEYTPRIRGRKPILTDVRSAFFMDALDKDGKLTLATLKQHLHKESGLTVSMTAIHKHITSKCMYSLKRSAPENFNQNSERILNALHDWVTGWQDRQGEFLERLIFIDEAGFQLHMVHMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZE5</accession>
    <name>A0A9P6MZE5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Bromodomain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_005578</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000275">
        <property type="protein sequence ID" value="KAG0019580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZE5"/>
    <dbReference type="OrthoDB" id="21449at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050935">
        <property type="entry name" value="Bromo_chromatin_reader"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027353">
        <property type="entry name" value="NET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038336">
        <property type="entry name" value="NET_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22880:SF225">
        <property type="entry name" value="BROMODOMAIN-CONTAINING PROTEIN BET-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22880">
        <property type="entry name" value="FALZ-RELATED BROMODOMAIN-CONTAINING PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17035">
        <property type="entry name" value="BET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51525">
        <property type="entry name" value="NET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bromo" evidence="4">
        <location>
            <begin position="253"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="Bromo" evidence="4">
        <location>
            <begin position="453"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="domain" description="NET" evidence="5">
        <location>
            <begin position="651"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="339"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="536"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="586"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="763"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="57"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="353"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="368"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="402"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="551"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="594"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="611"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="781"/>
            <end position="802"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0019580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="802" mass="88177" checksum="0EC6BD5F45E10F56" modified="2023-09-13" version="1">MMSNSDEVKKRPLDDLTNLNSEPNGHASLSHELSAHVPEETSLKRLKAEDDDRVPMSAATTTATITSTEQHPLVPSLDHARSDFSAPLGHSMSDQTIDSDMNVPNSLSNMPATNVLSGPQALAPAPEAAMLSLEQRNLDNIEVLKPELNSPTIPVVATTPAVVTTPTVASIPTVATAPTVATAPAVATTPTVTAAPTVATAPIVATAPTVTATPSNDLNNTQTTLNSPLNGVRKSTMTREQLKYCSAIIKQLKRHRDAPAFLHPVDPVLLKIPDYPLVVKHPMDLSTVERKLNDLEYYAVDDFVMDVNLIFNNCYMYNGRDSPVSICASNLEVSFHSSLRHMPRDNPKPAAEASAPKDLPKKASAPKAKKDLVKKEDIKTVTPAPVAPADHEPLNFSQSRAASEERRPKRDIHAPSKEMPTAIAVKKKGSGKWKADAQLRYCHAILREFAKKANAEFMFPFMEPVDYVKLGIPDYPKIIKNPMDLSTIRQKLEDDEYDNAAMFEADVRLVLWNCFKFNPAGTPVHMMGRKMESLFNDKWSERPPPPTPPVVEEEPMVESEDDIDSSDEKIAEMERHLKTLAEKIKQMKAAKKKEKAEKKSTKPQQEKPVKPKTASKTPAKTPAKPAPAKASAPDRKKAPVKRSRPVYSSDSSSSEDDVPVITFEQKKELSDSINKFEGDKLANVVQIIHNSMPHLRDNGGQEEIELDMDSLDPRTLFKLYQYVKKNTTVKRKRPVAKKVKVQYSEEDATKKITELERTLQKFEQPAAHLKNSHSNMNDGYSSSSSGSSSSSGSDSDSGSSSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZW6</accession>
    <name>A0A9P6MZW6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein phosphatase inhibitor 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004785</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000240">
        <property type="protein sequence ID" value="KAG0020095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZW6"/>
    <dbReference type="OrthoDB" id="551302at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004864">
        <property type="term" value="F:protein phosphatase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009966">
        <property type="term" value="P:regulation of signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007062">
        <property type="entry name" value="PPI-2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12398:SF20">
        <property type="entry name" value="PROTEIN PHOSPHATASE 1 REGULATORY INHIBITOR SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12398">
        <property type="entry name" value="PROTEIN PHOSPHATASE INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04979">
        <property type="entry name" value="IPP-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0020095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="220" mass="25254" checksum="3A0DC8E22E6EE7FD" modified="2023-09-13" version="1">MSDSIPPVLHSPILSAQPVKGILKRPASRQQHDERFPRLKWDEENLTITEAQKDSTMKIDEPKTPYVYYDQELDKVMDLDDAFSLDCEKKKKAGSSMQGVQNGNWSKQDSNDEEEQEEDDEEDEDEEDEWGDSDDEDEDEEEEEEEPKKIDHDKFARMRAEHYHMKEALKLGHQLAEEELNSLDSPSPTTEPVPPLPSFAKYQNSILDSSKGKGPNGMDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZY8</accession>
    <name>A0A9P6MZY8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_004789</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000240">
        <property type="protein sequence ID" value="KAG0020099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZY8"/>
    <dbReference type="OrthoDB" id="2447275at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0020099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="195" mass="21588" checksum="ADBC2F58D43A12D8" modified="2023-09-13" version="1">MTYCIQLYDNFHCVVPPGSESSPTAGALHGDAKIGKTLIQMGDKYRDNGEIKRAAQTYNLARTYSPREAQEKLNLMPQWSLSSESNTSTRNSFGEGYHRAKAKKAIIGVFKRPSSKPSLTGPFFPKGTHQSLPPLMSRDVLTPPETVCTFDKAQDTNSVVISYINGNEGIKSVLRIQINEIIKQFDDSFISLEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N024</accession>
    <name>A0A9P6N024_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glutathione s-transferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_004625</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000234">
        <property type="protein sequence ID" value="KAG0020187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N024"/>
    <dbReference type="OrthoDB" id="414243at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050213">
        <property type="entry name" value="GST_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571:SF150">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14497">
        <property type="entry name" value="GST_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="25"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="2">
        <location>
            <begin position="108"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0020187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="246" mass="27930" checksum="290C79C7004D173D" modified="2023-09-13" version="1">MSPTGRTFDDNARAVLNESIKKQDSTFKLKYFKLQGVAYTSRLILATTGAKWECVFPDDWANTEKKETLFGVLPVLYETTSSGQSIEVPESDAIEHYLSKKFQLYGQDDFDEIKIRAFASSLQSIISFYFLRVAVVRDEGYKEEMMKRFLTEALPPFVDTHERHLEANGRNGHYVGDKLSLADIKLTIAVNMIKAVTGDKFVSKEKTPAMWAVWETVSAIPSYVSWRETDSYETVSSGNMRIIGFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N028</accession>
    <name>A0A9P6N028_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_006126</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000301">
        <property type="protein sequence ID" value="KAG0019233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N028"/>
    <dbReference type="OrthoDB" id="2094445at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015986">
        <property type="term" value="P:proton motive force-driven ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021278">
        <property type="entry name" value="ATP19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28074">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT K, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28074:SF1">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT K, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11022">
        <property type="entry name" value="ATP19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0019233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="70" mass="7619" checksum="798A0E9285E24EB6" modified="2023-09-13" version="1">MGAEYVIFGRAIPTYKLALATYAVVAAPIVATKLSKKEASANVIQASSQDEEDFIREFVKAAEEEEPKNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N092</accession>
    <name>A0A9P6N092_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NodB homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_006319</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000311">
        <property type="protein sequence ID" value="KAG0019096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N092"/>
    <dbReference type="OrthoDB" id="407355at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004099">
        <property type="term" value="F:chitin deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009272">
        <property type="term" value="P:fungal-type cell wall biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050248">
        <property type="entry name" value="Polysacc_deacetylase_ArnD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10587:SF98">
        <property type="entry name" value="CHITIN DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10587">
        <property type="entry name" value="GLYCOSYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040305761" description="NodB homology domain-containing protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="NodB homology" evidence="3">
        <location>
            <begin position="148"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="386"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0019096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="445" mass="47628" checksum="9CA4C38F0B8A9D2B" modified="2023-09-13" version="1">MISLQYAAALATLLLATANAATPTSSYLPQSSPAFLPKFSAPTGVITAWPPANTAAALPSGPLSTAAFTLSGYPAMNEVVKNAATDPNIVPVIAAIDWTKVPNIPPTNDTIGASYPSSDPNCWWTKGGCVTPKISYIPQDIYYCPTPGTWGLTYDDGPMYYYPVTAENSKWAEPNLYDYLLNHNNQKADLFYIGSKVMGAPAAAQRGLNDGHVICSHTWSHPSMTTLTNAEVVAEFYYSLRMMKEVLGITPKCWRPPYGDVDDRVRAIAWQMGMRTIIWDLDTNDWNINGDQVAPGPGAITYTEANNTVNGWITNRENGNDTKQGHVVLEHELSNATITLTEFWLPTIQKLYNTMPATACNNIAQPYWEESFVYPIQGKVAVNTNGTSSTTPVTTISGSNSTSSSSSGTGSSGPSVVKSGAAAGQIQAVTSVMGLVFAAAVALVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0H6</accession>
    <name>A0A9P6N0H6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">XPG-I domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006214</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000306">
        <property type="protein sequence ID" value="KAG0019165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0H6"/>
    <dbReference type="OrthoDB" id="2396933at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006084">
        <property type="entry name" value="XPG/Rad2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081">
        <property type="entry name" value="FLAP ENDONUCLEASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="441"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="448"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0019165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1076" mass="122237" checksum="5C7FC4C233164F7B" modified="2023-09-13" version="1" fragment="single">MGVRLLWPFLLKNGYKPSLLHLSRTLLRPDCRFRIDVQGSIFSTICYAYSTCSTDDEAKSIVLRQLKKIANPSNSVLYLDGAPAEEKRVTHQLREEVRAKAIVAADKSTTQLVDRVNNNLRIRKQHFISIKKQLRKAFYWAPESRIALAQFLRNEGWEVIECTTEADYRIASDCNPGDVVISGDSDMLIYDNVSIIWRPISRGRFLVYDVVEVLNTLNINRTQLTVLGVVSHNDYNRNIYGLGCATNFSIIKDLKTTSVDASSMVAAYLADTRVILKNKDQTTFANSIKVFINGEQTPVPLVPGVLSSGPNLVTYDKTMAIFKQACDLYALKREEQREAGLTKKSSPPEERIWRHKPSQNFNRYRVIDRPPPKDNKAIADKVVKYPKSDMPSPKTPLHRPRYSFKTRTRQLEHEPPISMKQYTWKPWKEKPESPVDYSAEIESEPQEPIETPSTTTPTPVKDMNKYQLLRALSWEHPTVNLDIGTLSANVNGVLKDKDAVAQEVIGCIQEAVRLASEVKRQCQGLIGQYLELLDTPGVFDPSSDRQILDHLCPRIVPRTDNSNNLNVGEQNTNAGDFDDKGDKQEQFLASFLRFLYSGNFPSQTGVAKVANLFIKRLTTLNLLTPRSRSELNVPKEFNPTCLVRSVATQLAVELKKIYKNGSYELQEKLKCMKEQGRLIGDYNLEIRKEWSAIENFLALNKISKNSRRIAPMSSQEHQYMIFSERELLAFFWKRQLLKTKILEMTRIEFPNGVALDDLTSWIGSKGPGYLIKRLISDVAKEGLTKRQRGKAGVKAAVKLMAPDQIKEHLISLRQPTLDPQQYNTKGYLLRGSIRTDGFRIQLLAFKLKELQSVRYKRLPDDLLPPRITTTIGGTDYFLTEIRNIVKTKEDVTRLWPNCKPEEIKILGLDLGQACVIGASALLPDTARSIQEGKMKRLTEPNSSALTYPSSPSLPVSVFYNLAVKQKAVSQPTLKHRRWMEEQKSTTPLGALESVSDIETNLPPLRGEGTSYTGYVKELERVTQQLDDFYNGNNMRFKRHGWDARRARDAEFKVIANRLFKLVGGSIGCRRNEDNKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0X3</accession>
    <name>A0A9P6N0X3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Vesicle tethering protein Uso1/P115-like head domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BGZ80_005304</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000262">
        <property type="protein sequence ID" value="KAG0019763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0X3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012507">
        <property type="term" value="C:ER to Golgi transport vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005795">
        <property type="term" value="C:Golgi stack"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048211">
        <property type="term" value="P:Golgi vesicle docking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048280">
        <property type="term" value="P:vesicle fusion with Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041209">
        <property type="entry name" value="P115_Arm_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006955">
        <property type="entry name" value="Uso1_p115_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024095">
        <property type="entry name" value="Vesicle_P115"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006953">
        <property type="entry name" value="Vesicle_Uso1_P115_head"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10013">
        <property type="entry name" value="GENERAL VESICULAR TRANSPORT FACTOR P115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10013:SF0">
        <property type="entry name" value="GENERAL VESICULAR TRANSPORT FACTOR P115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18770">
        <property type="entry name" value="Arm_vescicular"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04871">
        <property type="entry name" value="Uso1_p115_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04869">
        <property type="entry name" value="Uso1_p115_head"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Vesicle tethering protein Uso1/P115-like head" evidence="10">
        <location>
            <begin position="464"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="domain" description="Uso1/p115-like vesicle tethering protein C-terminal" evidence="11">
        <location>
            <begin position="676"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="676"/>
            <end position="808"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF04871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0019763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="813" mass="90896" checksum="3FF1D3F20E1824A7" modified="2023-09-13" version="1">MDFFASGLNALRGQKGQHHSASETVDRLCERIEHGTLLEDRRAAVLALKACSREHKRDIGSRGVLVLCKVLRQDFMDVDISKAVLETLTVLCQADMDREETRDFALEMSNAVLQDANNVTILLEMLEENDFYIRFHIVSLLSTLVLNNAERLQECILTSPMGMSRLMDLLDDRREIIRNESNADLQKIVAFENAFERLLAIINDEGAIDGGIIVQDCLQLVQNLLRYNVSNQNYFRETSCIQRIPALFEEETVGDNRRHDPTIKDTWSDQKGNNMIMVLELIRVLVVPDHSNTAPNQKSMYQSGILQRLIDLSLTSNAPQRVKASAFYALAELIRLNKVNQDALSKAVIIPAHPPAVQLEDSSTALFPPNRSSTQLSRSSFQSGRGSALEARERCPAIVEVVAIAVGRYPGCTYSVRAAATCLFQSFVLDNPDTQVVLATTLNAPPEDNPNTTSYGTETNIKLNNARAKAIALSINFGDEENGEDPVSLIHAIAAALMVAVKGQSDVRVALGYLALLCVWCYDSPKSIKDFLSEGAHLQFLIELISPSSKEDLMVQGLAAFLLGICYEFNWEKDALISRATIQPIILSRIGLDQFAACITRVRESKPFKAAVPFMIVLPSEESEGKLPGLFFDYAFVEFMKRTFERTQKSIMLSPEDTQPQESLTQTNNAEIASQLASLQTKLSTQDAEMTELRSQLEEAQRIIAQQAQERQKCEAALSLAREELQSVQARHESLVNEHESIQARHESLEKEHESVLTRHESLGKEYESVLTRHESLEKEHEDLLICLAEQDEEMTGLKNQLQSLGLETSHAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N126</accession>
    <name>A0A9P6N126_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Choline kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_004940</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the choline/ethanolamine kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000247">
        <property type="protein sequence ID" value="KAG0019995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N126"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004103">
        <property type="term" value="F:choline kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004305">
        <property type="term" value="F:ethanolamine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006646">
        <property type="term" value="P:phosphatidylethanolamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05157">
        <property type="entry name" value="ETNK_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22603">
        <property type="entry name" value="CHOLINE/ETHANOALAMINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22603:SF93">
        <property type="entry name" value="RE24176P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01633">
        <property type="entry name" value="Choline_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="509"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0019995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="605" mass="68062" checksum="91658F3C40EF6796" modified="2023-09-13" version="1">MPSQTENPLRIETSKPVGEEIINESNSNDDETTSLEVESSWQEQPIHLPAYTPSSAAIEAARGSPPTSPIDDPIYITGSKKHFGFSSRQSRAAAIFPWQKHKPAVCHQYAPHRPPLSKRSSLAKLKVFPMSDPDPVKFMEDQELDIIKLKGDQLKERVLELLHLMEIQDWIQVTDYHQLTLDRISGAMTNCIYLVSGPPSESTTNSESATEPKPRKVLLRVYGVGLESLFSRKKELQWLHNLSTMDIGPSLLGIFMNGRFEQYVESTTLTKEDIRDPRTSRHIAHRMCELHNIVNVFPPPEGTIPQSQENIAKWIPLARDAIGKICAKDPSKKAIFDEFDFDKLLTEIDEVHRDLADVHSPLVFAHNDTQYGNILRTLDDSGELVVIDFEYAGYNTRGFDIGNHFCEWTADYHSERPSVLHPSRYPTKAEQLNFLEAYMEAEIAMCGYHLTAINIAKYAKKRKSITSTITKSLANVALSAVNAAQALRRGSTTELQKEEIAVSETVTKEEKVSVGNGPKGNTAGDKLNVNSRKHEAGDGGGGVTKAEILDSMYKEVNKFALTSHIMWGLWGLIQATQSEIEFDYVEYALQRLTEFRVRRDEFMSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N133</accession>
    <name>A0A9P6N133_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_002702</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000168">
        <property type="protein sequence ID" value="KAG0021281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N133"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016709">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050641">
        <property type="entry name" value="RIFMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004:SF19">
        <property type="entry name" value="BINDING MONOOXYGENASE, PUTATIVE (JCVI)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004">
        <property type="entry name" value="TRK SYSTEM POTASSIUM UPTAKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="29"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="208"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0021281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="365" mass="40346" checksum="FEB1AD07BF067599" modified="2023-09-13" version="1" fragment="single">MVATTLPPPSSSSSLSASSTCSTITTSSVPVLIAGAGPVGLFEAFLLTKLGIQVRIIEREMAISPLSKALGMQPRSLEIFGMVGIINKFLERGESLSSLNLYHGSKRTATFNPSVMTHSDSHYNSGLILEQAKTSEILVEELEKVGVKVDYGWELLDTKVVEEYEDDKTSGSGEKTKKTYVETTIRRALSGDNTAPDEKRYLGNTDLLEEQDDKEYEIHVVRSEYLVATDGGRSTVRHKLNIGFPGRTLDIKAMMWDGTYESDLKITGLTNIYGVNRKGVVAFPLPNGNYRIVVEAGKLDPNEDLSKTMESLTVEKFEELVSECIAPATFKVKTTSWLTVFKINERRAEHFVYKNRIFLAGDSAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1A1</accession>
    <name>A0A9P6N1A1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">DNA mismatch repair protein MSH2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">DNA mismatch repair protein Msh2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">MSH2</name>
        <name evidence="14" type="ORF">BGZ80_002832</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Component of the post-replicative DNA mismatch repair system (MMR).</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Heterodimer of msh2 and msh6.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the DNA mismatch repair MutS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000172">
        <property type="protein sequence ID" value="KAG0021216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1A1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032301">
        <property type="term" value="C:MutSalpha complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006312">
        <property type="term" value="P:mitotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051053">
        <property type="term" value="P:negative regulation of DNA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd03285">
        <property type="entry name" value="ABC_MSH2_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.110:FF:000002">
        <property type="entry name" value="DNA mismatch repair protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1170.10:FF:000003">
        <property type="entry name" value="DNA mismatch repair protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1420.10:FF:000015">
        <property type="entry name" value="DNA mismatch repair protein Msh2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1420.10:FF:000017">
        <property type="entry name" value="DNA mismatch repair protein Msh2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000925">
        <property type="entry name" value="DNA mismatch repair protein MSH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1420.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.10">
        <property type="entry name" value="DNA repair protein MutS, domain I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.110">
        <property type="entry name" value="MutS, connector domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011184">
        <property type="entry name" value="DNA_mismatch_repair_Msh2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007695">
        <property type="entry name" value="DNA_mismatch_repair_MutS-lik_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007861">
        <property type="entry name" value="DNA_mismatch_repair_MutS_clamp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007696">
        <property type="entry name" value="DNA_mismatch_repair_MutS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016151">
        <property type="entry name" value="DNA_mismatch_repair_MutS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007860">
        <property type="entry name" value="DNA_mmatch_repair_MutS_con_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032642">
        <property type="entry name" value="Msh2_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036678">
        <property type="entry name" value="MutS_con_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003810">
        <property type="entry name" value="PRK05399.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361:SF35">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MSH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01624">
        <property type="entry name" value="MutS_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05188">
        <property type="entry name" value="MutS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05192">
        <property type="entry name" value="MutS_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05190">
        <property type="entry name" value="MutS_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005813">
        <property type="entry name" value="MSH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00533">
        <property type="entry name" value="MUTSd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="DNA repair protein MutS, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00486">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 12" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8 12" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair proteins mutS family" evidence="13">
        <location>
            <begin position="745"/>
            <end position="761"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00064337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00073545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS00486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0021216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="970" mass="108498" checksum="F81E22A943B731B5" modified="2023-09-13" version="1">MSEASLKDRPEFDLDNQGEQKYCSFLRSLPERQENCIRLFERSSGDFYSVHGEDAYFIAQNVYKTTSVIKYLGGDVSTGVPSCTLSKTTCETFLRDALLNRQMRVEIWAAEPRKQNVWSIIKRASPGNMQDMEDLLFAHTDMTASPIVMAVKVQTGGDQRTVGVCFADATVRELGISEFIDNDLYSNFESLVIQLGVKECLIQADEGQKDYELTKLRTILQHCDIVITERKKSEFSAKDVEQDYNRLLEEDISIAALPEFELKNAMAASACVIKYLGLLTDETNFGQYALRNHDLSQYMKLDASAVRALNLMPGPQDGANKSMSLYGLLNKCKTTQGGRMLGQWLKQPLMDVAAIQKRQTMVEAFVLDVELRQNLQETHLKMIPDLHRLAKRFQRGVASLQDVVRAYQVVIRLPGLVGALSSCETGSSEHKEMLDSEFTTRFQEYTNNLQKLQDLVETTIDLEAVDRHEYMIKAEFDQSLKVLRSKMETVKQTMEREHERVADELNMEVDKKLKMEDHQVYGWSFRLSRNDSSCLRNKSSYIELTTQKNGVLFTTTKMRAASQSFSEASQEYERTQSSLAKEVIGIVSTYCPVLEQLNTLVAQLDVLVSFAHVSNHAPTPYVKPHMTAMGTGDVILKDSRHPCLEAQDDVAFIPNDVNLVRGKTEFLIITGPNMGGKSTYIRQIGVIALLAQTGCFVPCAEATLCVFDCILARVGAGDSQMKGVSTFMAEMLETASILKSGTVNSLIVIDELGRGTSTYDGFGLAWAISEHIATEIKSFCLFATHFHELTSLGETAPHVGNLHVSAHVGGDNGEATDDNANDIFNKNKNSREITLLYKVVEGVCDQSFGIHVAELAQFPDSVVQLAKRKAIELEDFSSLHHTMAVSTPAAKIGQTASEHKRAKLEDIEAGTALTEEIIQVISKDYKTSNKQGSQDRAAMLQTIERVRDQYHDRIQSNPWLKEQLAGVYWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1P6</accession>
    <name>A0A9P6N1P6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Mediator of RNA polymerase II transcription subunit 21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">MED21</name>
        <name evidence="10" type="ORF">BGZ80_002610</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the Mediator complex subunit 21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000165">
        <property type="protein sequence ID" value="KAG0021335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1P6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.280.10">
        <property type="entry name" value="Mediator complex, subunit Med21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037212">
        <property type="entry name" value="Med7/Med21-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021384">
        <property type="entry name" value="Mediator_Med21"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13381:SF0">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13381">
        <property type="entry name" value="RNA POLYMERASE II HOLOENZYME COMPONENT SRB7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11221">
        <property type="entry name" value="Med21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140718">
        <property type="entry name" value="Mediator hinge subcomplex-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0010">Activator</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 8" id="KW-0805">Transcription regulation</keyword>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="46"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0021335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="123" mass="13558" checksum="AF85827FB8855A63" modified="2023-09-13" version="1">MDRLTQLQDAIDKLALLFVSSLDHLTKNAPLVPLNQNIPVVNTDSAQELALDISRQAKELETLIDNLPGISQTPEDQTRDLELLGQQNAQATEDYEAAVSEAKILLQEVTLALRDIAEDQSHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N265</accession>
    <name>A0A9P6N265_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001643</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000138">
        <property type="protein sequence ID" value="KAG0021815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N265"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="321"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="325"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="364"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0021815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="565" mass="62267" checksum="775E84092D868B59" modified="2023-09-13" version="1">MPTAVGICLVRTAHSITSRNEDQFEDIFTTTANYNSDCNSYSNSNNIENATGNMLETKASAGTEILSEVEPLTKLVLSSPSTAAPTSTSSSTTLASTLTVPSTPLLDIENLVAQKQHQITYIEKQQTLQLLYHHQPLHQRQQRQQGQEKKLDRHQERQEGDGCYTKTQQKQEHSLGSDRSNCNFNHHISRDQERTTTNPSASDENTSTVTITNSETSKTSGINASATTITTITTISNTDKKPDLVDDIWRLIFYVLARDCKDLGRSMQVNRRFYSLIANDAVLWKLTYNLTVSGSIFATQKPLSSSSLVRVEQSHLAYSAGEGSMSGSFQGTPSSESRSGQSHNLGMNEDGPSSVMLMNQPEPRYPRRNETDGDVTESRRASLTVNPGLQLPSPLILPHHRRIAQSIYTSNLTVHGGSSNQDNSENEDIGSTGIQPIVDHSIDLQSSFISGTPPYLSTSLTNGKITFCRTPTSTPSPSCISSFQSTIPATISQVVSSSTTPLSAIYNHIPTATSLHRDPAVYWKDQVVEWLEREKLRRLRLGLFWGFNAASSRTHGRRMKNCGYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2B9</accession>
    <name>A0A9P6N2B9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Peroxisomal ATPase PEX1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Peroxin-1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">PEX1</name>
        <name evidence="15" type="ORF">BGZ80_011773</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:13066"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000099">
        <property type="protein sequence ID" value="KAG0022561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N2B9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016558">
        <property type="term" value="P:protein import into peroxisome matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19526">
        <property type="entry name" value="RecA-like_PEX1_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000149">
        <property type="entry name" value="Nuclear valosin-containing protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050168">
        <property type="entry name" value="AAA_ATPase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029067">
        <property type="entry name" value="CDC48_domain_2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015342">
        <property type="entry name" value="PEX1-N_C-lobe"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077">
        <property type="entry name" value="AAA-FAMILY ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077:SF12">
        <property type="entry name" value="PEROXISOMAL ATPASE PEX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09262">
        <property type="entry name" value="PEX-1N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="ADC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54585">
        <property type="entry name" value="Cdc48 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0962">Peroxisome biogenesis</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="14">
        <location>
            <begin position="518"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="14">
        <location>
            <begin position="833"/>
            <end position="969"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="353"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1031"/>
            <end position="1054"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1168"/>
            <end position="1188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="1035"/>
            <end position="1054"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="1171"/>
            <end position="1188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00034532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0022561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1188" mass="128496" checksum="41EEB81B73CB5CC3" modified="2023-09-13" version="1">MHKSVTVAFLPVRHCLISLPSSWANALLDQGKLSQNVVLELSWQEGSTEKKSYVGWSGGASSGVGGAGNGIPAPPRPGANTGDTIEMDPQFGQAMGLRAGQKVNIDFVKSVQDGISVNVAPYSEDDWEILELHAGYVEDQMLNQIRVLYPNQIITMWVNGRTLVRLRVLDINPTAPCVKLGANAEVIVAPMVRKANGGAKPSDNQDLSSHVQKVTQAQCLRVLALDECSDDLVESIPEAGPFIVQVHPDSWIEADLTNQPALRISRVNPPHVEKVADDETRDLEDLLVGSSAIYVRAISSYNVPIGHVAISKQVQDAIDADNFSIVRLSESHINAVPIPSVVLRPISAPGATPTTPAPLKLQPKSASHDSEKAAKTTNMISIFKEWIDSLPEGDNVIFTHGSLLTIPHGDSIQSFSIVFPPKSLPSTNTNSQQDEAKNQPEPEVYSIMSKAQLNQLKVEIGQAQGISHVFKKPFRTVTHIADTPAALGGVTQVCTKAEKYLLTCLSKLELRDAFSVPSLGGFLLCGPHGSGKTVVARSIIRKLSQNIDTLAYCVEINCAEFAEDRIPVLMTKFQQWFDTAAFHSPSILFLEDLDRLIPAEVEHADSFRSRQIAEVFLQIASKMCKRFDRIAIVATAQQQVSIHPSLITSHLLSEIIRLTPPGKTERKEILQSLMETGPAILQRSLPQIDLVSVASKTEGYLAADLKAFLERTVHEGAVRNIASQVAIRKDEEDAAQSEKHVSANGKAKAIDSVQEPSLLSGSSSEDDFTLTQADFLKAQEGFVPSSLRGVKLQSSATSWLDIGGLNETRKVLLETLEWPTKYSSIFSQCPLRLRSGLLLFGHPGCGKTLLASAVAKECGLNFISVKGPELLNKYIGASEKSVRDLFERAQAAKPCVLFFDEFDSIAPKRGHDSTGVTDRVVNQMLTQMDGAEGLDGVYVLAATSRPDLIDPALLRPGRLDKSLLCGMPNLQERFEILTCLARKMEVAEDVDLMECARRTDGLTGADLQAVLYNAHLEAIRVAIEKDEAIKKERQSNNGDNGSSSPTIGGANSSQTDGKVMRFVSLGGKGFGGAGKANQKANLTLAERGHISQRLGLIAKGMNAAREAASAATKDASSEGNLADKAPKGSRPIITAEHLEVSLTNTRSSITPEESQRLDLIYKEFMGDRTGEMSNGTGSHELGQRTTLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2Q6</accession>
    <name>A0A9P6N2Q6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">histone deacetylase</fullName>
            <ecNumber evidence="2">3.5.1.98</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">RPD3_2</name>
        <name evidence="12" type="ORF">BGZ80_011339</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the histone deacetylase family. HD Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.98" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010000090">
        <property type="protein sequence ID" value="KAG0022733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N2Q6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070210">
        <property type="term" value="C:Rpd3L-Expanded complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032221">
        <property type="term" value="C:Rpd3S complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141221">
        <property type="term" value="F:histone deacetylase activity, hydrolytic mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031507">
        <property type="term" value="P:heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.800.20:FF:000001">
        <property type="entry name" value="Histone deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.20">
        <property type="entry name" value="Histone deacetylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003084">
        <property type="entry name" value="HDAC_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000286">
        <property type="entry name" value="HDACs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023801">
        <property type="entry name" value="His_deacetylse_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037138">
        <property type="entry name" value="His_deacetylse_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625:SF10">
        <property type="entry name" value="HISTONE DEACETYLASE HDAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625">
        <property type="entry name" value="HISTONE DEACETYLASE HDAC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00850">
        <property type="entry name" value="Hist_deacetyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01270">
        <property type="entry name" value="HDASUPER"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01271">
        <property type="entry name" value="HISDACETLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0678">Repressor</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Histone deacetylase" evidence="11">
        <location>
            <begin position="37"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="389"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="483"/>
            <end position="996"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="401"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="412"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="427"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="516"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="544"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="564"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="616"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="662"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="693"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="716"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="747"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="804"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="815"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="848"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="860"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="895"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="972"/>
            <end position="986"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0022733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="996" mass="109012" checksum="008F5AC171651A88" modified="2023-09-13" version="1">MTTGFSSFALGGGATQKQRVSYFYDDDVGNYTYGLGHPMKPHRVRMCHSLVTNYGLYKKMDVIRPKRATARQMTRFHNDEYVDFLYRLTPEMVGGEGMSEQTKHLFNLGDDCPVFDGLFEFCSISAGGSIAAANKLIRGESDIAINWAGGLHHAKKTEASGFCYINDIVLAILELLRYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTASFHMTEFFPGTGKLEETGIGKGKNYAVNVPLQKGMDDWSYQNLFEPIIKHIMEWYRPGAVVLQCGADSLAGDKLGCFNLSMKGHANCVAYVKSFGVPMIVVGGGGYTIRNVARAWTFETAVLLNQQLPEELPFNSYFEYYGPEYRLDVPANNMKNDNTPEDLHNLKAQIIENLRHIPCAPSVQMQEVPRDYTSSDDEDEDEDMDVRVSRRLVDSRIVPDEELSDSEDEDGRRNIHDANGSSIIGSPAMANSTVALGPANGSSVGAAVGHNRKFASAAPPETSQSKPGSAQAEWGPTPGVKSSKSVLGANANASAAARRIGRTVTGTTTPSTKTNGKELQTSTIQPHTPHATPSASKGREIHSKEYQPRESHHREPLHHSQPPQQGIHGQGMPPQSHLQSGPPPHHHLPRDQHMQIQQQREHQMHREQQHRDMQLMREQEHREQEQREREHHHQLQMQRRAGGSTSSSRSEYHSQYPVDDMIRYGGPQGSGGSHGGYPQHPSSMHYGQGPPPPQGSGLPPPNQPPPHGHMHSGSSSHGGPHSHSHSHSHSLHHHSQGVPHGSHVQHSGPPPPHHHMPLHHPSMSQHSHHHGPPPPASQQSSGHHYSGSTGGSSGSRGGSVGMSQGRPGSSSGPMTGMHSSGYGGPSGGYGGYIDRHEEGPVVHRDRKDHYKESASMDLDDPRIMDGRGPPPSHGGPMPPMGHHSHPSHGGSMDYGRMMPGGPAPPPSHYGHRRGGSHGGSQGDLRAVVMGGETPGAGGPYSGWDRGMERERERERDRDRHHVYRGPNAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3X6</accession>
    <name>A0A9P6N3X6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">AP complex subunit sigma</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_010725</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasmic vesicle</location>
            <location evidence="2">Clathrin-coated vesicle membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the adaptor complexes small subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000078">
        <property type="protein sequence ID" value="KAG0022959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3X6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030121">
        <property type="term" value="C:AP-1 adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016482">
        <property type="term" value="P:cytosolic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.60:FF:000007">
        <property type="entry name" value="AP complex subunit sigma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016635">
        <property type="entry name" value="AP_complex_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022775">
        <property type="entry name" value="AP_mu_sigma_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11753">
        <property type="entry name" value="ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01217">
        <property type="entry name" value="Clat_adaptor_s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015588">
        <property type="entry name" value="AP_complex_sigma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AP complex mu/sigma subunit" evidence="10">
        <location>
            <begin position="1"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR015588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0022959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="162" mass="18922" checksum="B7A3C9F300E18FC2" modified="2023-09-13" version="1">MINFILIFNRQGKIRLTRWYQYMTDKQKSSLSQDVVTQILARKRGMCNILELEGRRETRGKAIYKRYASLFFCFGIDWNDNELSGLEVLHKYVECLDQYFGNVCELDIIYNYSAAYQVMDEMLLGGHAQETNKKTVVKHCKGFDKLEESDSIVHNLRASNIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N448</accession>
    <name>A0A9P6N448_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">40S ribosomal protein S3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">RPS3</name>
        <name evidence="8" type="ORF">BGZ80_002424</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000016">
        <property type="protein sequence ID" value="KAG0024473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N448"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02413">
        <property type="entry name" value="KH-II_40S_S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1140.32:FF:000004">
        <property type="entry name" value="40S ribosomal protein S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.20:FF:000006">
        <property type="entry name" value="40S ribosomal protein S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1140.32">
        <property type="entry name" value="Ribosomal protein S3, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004044">
        <property type="entry name" value="KH_dom_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036419">
        <property type="entry name" value="Ribosomal_S3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057258">
        <property type="entry name" value="Ribosomal_uS3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001351">
        <property type="entry name" value="Ribosomal_uS3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005703">
        <property type="entry name" value="Ribosomal_uS3_euk/arc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01008">
        <property type="entry name" value="uS3_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11760">
        <property type="entry name" value="30S/40S RIBOSOMAL PROTEIN S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11760:SF32">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07650">
        <property type="entry name" value="KH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00189">
        <property type="entry name" value="Ribosomal_S3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="Prokaryotic type KH domain (KH-domain type II)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54821">
        <property type="entry name" value="Ribosomal protein S3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="KH type-2" evidence="7">
        <location>
            <begin position="21"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="Small ribosomal subunit protein uS3 C-terminal" evidence="6">
        <location>
            <begin position="93"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0024473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="228" mass="25132" checksum="51FAFE3DF90D45CA" modified="2023-09-13" version="1">MASAQISKKRKFVADGVFYAELNEFFQRELAAEGYSGVEVRVTPARTEIIIRATQTQEILGKRFKFPENTVELYAEKVSFRGLCAIAQCESLKYKLLNGVAVRRACYGVVRYIMESGAKGCEVVVSGKLRGARAKAMKFVDGFMIHSGQPTKDFVDTAVRHVLLRQGVLGVKVKIMLPWDPQGKMGPKTPLPDMVTIMEPKEEAPILAPISESREEVVAPVAVAPVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N6X0</accession>
    <name>A0A9P6N6X0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Adenylyl cyclase-associated protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_003698</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">The N-terminal domain binds to adenylyl cyclase, thereby enabling adenylyl cyclase to be activated by upstream regulatory signals, such as Ras. The C-terminal domain is required for normal cellular morphology and growth control.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the CAP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000002">
        <property type="protein sequence ID" value="KAG0024839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N6X0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008179">
        <property type="term" value="F:adenylate cyclase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019933">
        <property type="term" value="P:cAMP-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.330:FF:000001">
        <property type="entry name" value="Adenylyl cyclase-associated protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.330">
        <property type="entry name" value="Adenylate cyclase-associated CAP, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001837">
        <property type="entry name" value="Adenylate_cyclase-assoc_CAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013912">
        <property type="entry name" value="Adenylate_cyclase-assoc_CAP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013992">
        <property type="entry name" value="Adenylate_cyclase-assoc_CAP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017901">
        <property type="entry name" value="C-CAP_CF_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016098">
        <property type="entry name" value="CAP/MinC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036223">
        <property type="entry name" value="CAP_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053950">
        <property type="entry name" value="CAP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036222">
        <property type="entry name" value="CAP_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006599">
        <property type="entry name" value="CARP_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10652">
        <property type="entry name" value="ADENYLYL CYCLASE-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10652:SF0">
        <property type="entry name" value="ADENYLYL CYCLASE-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08603">
        <property type="entry name" value="CAP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21938">
        <property type="entry name" value="CAP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01213">
        <property type="entry name" value="CAP_N-CM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00673">
        <property type="entry name" value="CARP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69340">
        <property type="entry name" value="C-terminal domain of adenylylcyclase associated protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101278">
        <property type="entry name" value="N-terminal domain of adenylylcyclase associated protein, CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51329">
        <property type="entry name" value="C_CAP_COFACTOR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C-CAP/cofactor C-like" evidence="6">
        <location>
            <begin position="371"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="251"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="319"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="263"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="322"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="344"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00054756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00072052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0024839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="532" mass="56818" checksum="9CA65A3AA5B341AE" modified="2023-09-13" version="1">MAEISSLSSLLKRLEAATTKLEDLAMAGVSASNVSSSLTGNSGAHAPQGQLSQLAEGAPAGASIQQDSIHPNVEGFDELLDGPVKNYAELSKAAKYVCSLFAAQREMVLVATLSQKPPLTSDVFRQLLAPTQAELTKVIEVRDKNRTSPLINHLTTVADGIPALGWVAIEPKTAPYVGEMKDSAQFYANRVVKDWKEKYAYHNAITLTPKDQNHVLWVRSFINVLNELQNYVRKFHPTGLVWNPKGNALDPNSLSRASAPTPVAAPPTPAPAAGGPPPPPPPPPPPPPPMLDAPVAKKPTETDMSAVFAQLNQGEAITANLRKVDRSKMTHKNPELRASGMVTSSSGKPGSPKRAGPGAPPKPAALTLKKPPKLALEGNKWVVENFENNNEVILDNVEINQSVYIYGCKNSTIQIKGKVTTVAMDSCAKTGLCLESLISSLDLVNSKSVQVQILGRAPTISLDKVDSCMVYLSKDCLDVEILTSKCSSVNILTPDSTEEGAEGDFVERPVPEQFLTKIVDGKVVTTAVEHAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N780</accession>
    <name>A0A9P6N780_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_010828</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000008">
        <property type="protein sequence ID" value="KAG0024671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N780"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="217"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="245"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="309"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="392"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="681"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="245"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="451"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="476"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="688"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="714"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="785"/>
            <end position="796"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0024671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="796" mass="85503" checksum="996D9D30BE9FFE8F" modified="2023-09-13" version="1">MPRTKLSSTNTSSATATTLNDLSTPSTSPLVPSPSLPLTALTSTLTLKTPNQQHVHDSTLSLPIGTTLTVPRKNGSRIGQSILGQLLAAHKPGRDHHKLAHDATLSLETIRPKEQQRRSILPSSWSVFQKSTSIQGLSMAPSHSVMQHSGTKMVPGSTSGSNRNVMENLDQNEQPMLPSVWLESVLSQLSRSESNTLSHYATLPRVDSHERRQPALQPMFNDLDQQPKDKKKNDKTNATRLRSALSHSALSSKSKSAAKLNVKPQTLTRRGSACELALGEDARELFQQNRPKTLSSAIITSSIVPVKDARDVMDSPKNSRQRSLDSSVAMKVPTQSPNTPELAPEPPAQSGTTTTTRGRFIIESSSSSSTPNPRTRTLSCAAAASSIPMLTGHLSVPTEKPPTMSPEKSFLSKPPSPTRSFSLPPPTLESVNRIPPPSPSLSPSRFTVHDSSLNGQGSSSTSNPILIPRPTKPNHQRTQSNSSTQSSASASSSRRSQVIIPPPVCTSSLQFASFASIAPNVSPTSRRAIQNNNNKNNKNNFRNLSIQIVDSPDKCDAGLDSHDSQVFHLDTPAIHPLDEDASARRESYGARSEMQIAHQTMNRVHPHQGLTDNSGDCAPPLTACSTSCSSVSSMSSSLGNYGNGSRIVGQYGSDQSYHGCDRNPPGIGYLRQRSLSAANFDSHHVPQRSPSHGNLQVQQQEGTWSERPTRRSHGSVSSSEHCSNGMPIKGMSENKSGPSVSSSYGGGVSDIVIKKSATGRMFTVERTIPASPTKSSRFTLVTSPTLPPRSPSPLQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SQL5</accession>
    <name>A0A9P6SQL5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_008780</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004891">
        <property type="protein sequence ID" value="KAF9991970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SQL5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9991970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="66" mass="7337" checksum="60361209307177A5" modified="2023-09-13" version="1" fragment="single">DEVEIEGEMNNITVKVYAADTTETAIQAYSPLAKTIRTLQLEYSGAKKCKMVVTVTRGCGCSTYRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SS91</accession>
    <name>A0A9P6SS91_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminoglycoside phosphotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007631</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003942">
        <property type="protein sequence ID" value="KAF9995007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SS91"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051678">
        <property type="entry name" value="AGP_Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310:SF40">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21310">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="141"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9995007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="389" mass="44324" checksum="566A1C9FA897BEB4" modified="2023-09-13" version="1">MDFKTESGILQYLQSHDKTRSIVTVKKLSGGNANYVYRGTIGEPCIDIFGGRSTVVIKHAADHSASSRQMALYVDRMAFERAILGIVADASDNKNNNNKEDEKIETSNVKVPRVLYWDHENNIVIQEDAGMKSTHLKEFISSHTQPPSPRLAKEIGSSLGEFIARLHLYGFCHRSELYPNKMANTEALSLSRLILYDQFPKAVSKYMEDQPQFDQDVINLASKWGGDRLMNEPETLAHGDFWPGNFLIDTATGEGNEITIKHIYIVDWEMSRYAPAAMDLGQFIAEAFSLNKYRHPCEELMTSFLEAYCNIYGDRLTTTDLKTAVIHCGGHLMSWTPYTGWFKEDESHDAKTKEITLIGAEFIKRAWIEDWAWVRQETAFHVMVDYLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6STK9</accession>
    <name>A0A9P6STK9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">NAD-dependent histone deacetylase sir2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">SIR2</name>
        <name evidence="10" type="ORF">BGZ80_006273</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sirtuin family. Class I subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003092">
        <property type="protein sequence ID" value="KAG0000892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6STK9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046970">
        <property type="term" value="F:histone H4K16 deacetylase activity, NAD-dependent"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01408">
        <property type="entry name" value="SIRT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1600.10">
        <property type="entry name" value="SIR2/SIRT2 'Small Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050134">
        <property type="entry name" value="NAD-dep_sirtuin_deacylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003000">
        <property type="entry name" value="Sirtuin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026591">
        <property type="entry name" value="Sirtuin_cat_small_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085:SF9">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02146">
        <property type="entry name" value="SIR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="9">
        <location>
            <begin position="251"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="540"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="592"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="720"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="541"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="378"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="386"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="389"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="410"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="413"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0000892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="782" mass="86276" checksum="CB0516E40EEC19D5" modified="2023-09-13" version="1">MTEYRSSQDYIDDQLSPQTSPVLEPISPASPVSTSSNAQLRRCLSPVDATVPPVIPLLTRSSTLEEIKPTTPLSLPNESETAIENLSLGTRGSTVPGRGPGLERAMGVITISRQGSPALGIVDKAARETTPILMEEEIVQHLETSQIMAGSSDPRDVSSSIDTMDTVGHSYFHESHLEPSDSSENEDADYELAADTTVDENFNRIDTSESEDDDSFSDIHINNIASNNYDAESRGNSYTDLDPMCLDRLTQEEKEMIMEEAREFDLLQNSKNIMVLTGAGVSVSCGIPDFRSPDGIYSRLAEFELDDPSQMFELEFFSEKPEVFYSFAKEIFPSNFTPSPSHNFIKMLEDQGKLLRNYTQNIDTLEQKAGIRNVLQCHGSFATASCIRCKHQVPGDDIKESILKQQVAYCKVCRTPSPALQSQPDVLESVMKSVGEHDVSAAVMKPDIVFFGEQLPSAFDDNFDEDRDKVDLLIVIGSSLKVAPVSDIMHRLPRNIPQILINRTPITHMEFDVQLLGNCDTIVAELCRMAGWELKHEQLPGGTSNIPSMNKNSNADGSGKDGRARWSLIEPNTYLFEGAILGDIEYELSQNSSKERGHSTHNDLGGYEADSDEDGGDLWGRSFRRVRRLSSPGLMDADCDSDDDSDESQGTIRCVQSSLFFDGTMESSLDETLELSPGFVVGARGSLSANIPEIHLSEASYSQESSLLDYSNMVNNVHSDHQEKENDNSNDSVESTEKAPRDLVQSEQDDEFGSLHVDPQQIIDLESIVEDPQSENVSGSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SUJ5</accession>
    <name>A0A9P6SUJ5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Homeobox domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_005784</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002844">
        <property type="protein sequence ID" value="KAG0003526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SUJ5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017970">
        <property type="entry name" value="Homeobox_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051000">
        <property type="entry name" value="Homeobox_DNA-bind_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24324:SF9">
        <property type="entry name" value="HOMEOBOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24324">
        <property type="entry name" value="HOMEOBOX PROTEIN HHEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00027">
        <property type="entry name" value="HOMEOBOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 4 5" id="KW-0371">Homeobox</keyword>
    <keyword evidence="3 4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="7">
        <location>
            <begin position="23"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="4">
        <location>
            <begin position="25"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="335"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="500"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="561"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="635"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="39"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="123"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="139"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="158"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="219"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="500"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="566"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="809"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0003526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="809" mass="87999" checksum="35C1B4B051BA0901" modified="2023-09-13" version="1" fragment="single">MTEPMEVEFQSPHGELRTAFYNPHEVKRRRRTSPGQFKILERSFSDNPKPDASTRRQLAQKLSMSPRGIQVWFQNRRAKNRQTSNTANSISNNDSNSTSTDLTDVDHHSNTNNDQDALPGSPFTPTSFSDQQHEVSLNSEKRSDDDMRGSLRSPTLQRAASSRSSVSSEVSIGPGLLPTTPPPHMSDPGTFPNSRDDGLTMSNSWESQMEWKNHPSLDGKSSLSSNPPAQQPSGSNPTPNTDSPIDLSFNRNHIYPATPPGEDSKNSYSNNTLILGGQHQTQNTLQYVAPQAPANGDSGVNHQRPSTLSLMRRMSMPATIRINNIPGTSVWSAHHPNPSTEDLKHPPASASQGHIGTEMQPPQHGHATPSRSREMGTTTRVRTYPLSRRVSVHETGIYSTQSTTKSKNVFSTDVQKTSHSEAESLAAAAAARRRRRSSVGKVASALSVGPPAPVIHAVDFIGAPQAGISASTLSTSVSPGIPGFAAPTSVFQTNPVIDNITSRHSPNIPQNGATSGFDRKTMDTWMNESDIDHTPPTEGRSSDVNGTIDHVMGSLMIGPPLPSELTDGTVNQQLSGPPTPENGFGAASVPRALTPGGTEQRSDIKSGRRRSSLRSIKGRLLPGVRVQFDLQMTPADLDQPPVLDGGENSMLQQSQEQQQYVTKDVTPDQAFMQNRWLNDSLFSIPMSGTVQMNPFDTSSTTNMAANMSQITMSPLDIRGQEGGSTDTYFACLPNISMANQALDEPDQTLQTLQDPHNARRNSCPARFVEYIRRGQHIEAGLPETNSGHAPTQHDLAMLQLQQQLQQQLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SUY3</accession>
    <name>A0A9P6SUY3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">protein disulfide-isomerase</fullName>
            <ecNumber evidence="3">5.3.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">MPD1</name>
        <name evidence="11" type="ORF">BGZ80_005537</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Catalyzes the rearrangement of -S-S- bonds in proteins.</text>
            <dbReference type="EC" id="5.3.4.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum lumen</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.4.1" evidence="3"/>
    <dbReference type="EMBL" id="JAAAID010002729">
        <property type="protein sequence ID" value="KAG0004863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SUY3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003756">
        <property type="term" value="F:protein disulfide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034976">
        <property type="term" value="P:response to endoplasmic reticulum stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057305">
        <property type="entry name" value="Thioredox_PDIA6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45815">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE A6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45815:SF3">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE A6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24541">
        <property type="entry name" value="Thioredox_PDIA6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040251020" description="protein disulfide-isomerase" evidence="8">
        <location>
            <begin position="21"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="9">
        <location>
            <begin position="89"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="PDIA6-like C-terminal thioredoxin-like" evidence="10">
        <location>
            <begin position="303"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="278"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF24541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0004863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="459" mass="50545" checksum="DC18DB8D5D36DFBE" modified="2023-09-13" version="1">MKSLTSIALGALLLSQTVLGLYSSKDRVVEMTTQNFQSEVMDSNSWLNSMLPGAATAKSRFSTCKSYPYCSKLGSLISRLNAIHVGNSSSLAPQYKAAADNLHGIVKMGAIDCDNDKNKPICGQYGIQGFPTIKVFPANRSGKKGVKYPKDYQGERSAKAIVDFLVKMLPNDIKLVSSNPSSERVTNIDEFVANENEPRALLFTKKLTSSNMYKGLATDMKDRMIVAEMRTPSDEVLKKFNVESAPALVVFPKGSQEPINFSGDLKRDPISEFLNEYAEPAKNGGSGSGSSKKSSQSEPVATPVAEFNPKIDQIVDQAQLTKECLDKSQDTCVIAFLVVEPEFPESVQAHEENLELLRKVKKASYDVGKSLQVMWMDALDKRVVNFMNQFQLSSDIPGLLLVKPGRKAYAPFMGQFDFEGIQEWLSGLSNGRTRAFVYSFDVQLAESKSESAKKPKDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SV95</accession>
    <name>A0A9P6SV95_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ras GTPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RAS1_1</name>
        <name evidence="4" type="ORF">BGZ80_005203</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002580">
        <property type="protein sequence ID" value="KAG0006628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SV95"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020849">
        <property type="entry name" value="Small_GTPase_Ras-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24070">
        <property type="entry name" value="RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="103"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="109"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0006628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="141" mass="16496" checksum="26D9F7A2CEE26087" modified="2023-09-13" version="1">MREQYMRTGEGFLLVYSITSRNSFEEISTFYQQILRVKDKDFFPIILVANKCDLEHERQVSTHEGRELAKQFSSRLIETSAKQRINVDESFYNLVREIRRFNKETHSSQPQNGGYGYAQQGQGYGNQMDDKDEKGCCCLIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SVM4</accession>
    <name>A0A9P6SVM4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein YOP1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">REEP4</name>
        <name evidence="3" type="ORF">BGZ80_004881</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002441">
        <property type="protein sequence ID" value="KAG0007267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SVM4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004345">
        <property type="entry name" value="TB2_DP1_HVA22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12300">
        <property type="entry name" value="HVA22-LIKE PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12300:SF117">
        <property type="entry name" value="LP05237P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03134">
        <property type="entry name" value="TB2_DP1_HVA22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0675">Receptor</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="214"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="269"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="222"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU362006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0007267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="304" mass="33527" checksum="F9C6E2921FB3928D" modified="2023-09-13" version="1">MLLYIVSRMVSTIAGSVYPAYASYKAINSRNSTRLTAWLMYWTVMGLFTLVELFLDTFIFWFPFYYEIKLLFVLWMILPQTQGSIYLYQTFVDPYLAQHENDIDRALKDMQKQAMDMGMQYIKQAIQLIQNLVLDLYKKSLNQTGTSSVAEDKSAASLTAQSASVTSEATTAGETTNTNASSTQTYFSWAYHALSPKLSAVATMASEAALRQMPAVGRPPVSGSSTDSTSSKEPPVSVNGESIFGIATTTSDSISPSEKAELEQLRYRLNKASESTGSGSLRYRKISLYEDDDGGNSPTGSTNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SVP5</accession>
    <name>A0A9P6SVP5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="20">Phospholipid-transporting ATPase</fullName>
            <ecNumber evidence="20">7.6.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">BGZ80_004761</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15 20">
            <text>ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.</text>
            <dbReference type="EC" id="7.6.2.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-L-serine(out) + ATP + H2O = a 1,2-diacyl-sn-glycero-3-phospho-L-serine(in) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:38567"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57262"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="17">
            <dbReference type="Rhea" id="RHEA:38568"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out) + ATP + H2O = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66132"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="16">
            <dbReference type="Rhea" id="RHEA:66133"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 19">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endomembrane system</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Golgi apparatus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 20">Membrane</location>
            <topology evidence="2 20">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 20">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.6.2.1" evidence="20"/>
    <dbReference type="EMBL" id="JAAAID010002396">
        <property type="protein sequence ID" value="KAG0007348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SVP5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140326">
        <property type="term" value="F:ATPase-coupled intramembrane lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032456">
        <property type="term" value="P:endocytic recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045332">
        <property type="term" value="P:phospholipid translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006892">
        <property type="term" value="P:post-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000010">
        <property type="entry name" value="Phospholipid-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006539">
        <property type="entry name" value="P-type_ATPase_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032630">
        <property type="entry name" value="P_typ_ATPase_c"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01652">
        <property type="entry name" value="ATPase-Plipid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092:SF150">
        <property type="entry name" value="PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092">
        <property type="entry name" value="PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16212">
        <property type="entry name" value="PhoLip_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 18 20" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10 19 20" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14 20" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 19" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 18 20" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 20" id="KW-1278">Translocase</keyword>
    <keyword evidence="6 20" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 20" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="251"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="291"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="334"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="368"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="399"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="439"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase C-terminal" evidence="21">
        <location>
            <begin position="220"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00008109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00034036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00049128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00051303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="RuleBase" id="RU362033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF16212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAG0007348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="539" mass="61668" checksum="1A523DCD40B06710" modified="2023-09-13" version="1">MREIPEKEYQQWSQIYDRAATTIQNRSEELDKAAELIEKNLFLLGATAIEDKLQDGVPETIHTLQQAGIKVWVLTGDRQETAINIGYSCKLIQEDMSLIICNEATHWETMEFLENKVKAIKSTYQRGEDIEPLALIIDGKSLEFALEKDVEKVFLELAVLCKAVVCCRVSPLQKAQVVKLVKRNLNAILLAIGDGANDVSMIQAAHVGVGISGLEGLQAARSADFAISQFRYLKKLLLVHGAWSYQRLSKLILYSFYKNICLYTTQFWYAFYNGFSGQTVYESWTISLYNVVLTVLPPLMLGIFDQYVSARMLDRYPQMYMLGQKGEFFNVRNFWGWAGNAIFHSILIFFCVYGIFKNDFIASNGTIGGMWVMSVTLYTAVLATVLLKAALITDLWTKYAYISVPGSMIFWIGFFPLFAVVGAATGLTPDYHGIIGPVYGQPAFWLTIVFLPILCNLRDFTYKYMKRTYFPRTYHYVQEIQKLNIPDYRPRMERFRKAVHKVRNIQRMRRNRGFAFSQSESGTARLIRAYDTTTQKPRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SW16</accession>
    <name>A0A9P6SW16_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004219</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002178">
        <property type="protein sequence ID" value="KAG0007790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SW16"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0007790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="105" mass="11750" checksum="C82DF7E2EEB2AEFC" modified="2023-09-13" version="1">MTSVVILDANALKNVVIVGWGETLHPAHAIVGANLVEKLTEAATNWINKIDIQRRHIVFIFIATLWFFCRFVLFIIVIASLSSKAAQALFSIISSEMLRNIGDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SW47</accession>
    <name>A0A9P6SW47_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">FAD-binding FR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_004059</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002113">
        <property type="protein sequence ID" value="KAG0007932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SW47"/>
    <dbReference type="OrthoDB" id="167398at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043020">
        <property type="term" value="C:NADPH oxidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016175">
        <property type="term" value="F:superoxide-generating NAD(P)H oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:monoatomic ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042554">
        <property type="term" value="P:superoxide anion generation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000778">
        <property type="entry name" value="Cyt_b245_heavy_chain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050369">
        <property type="entry name" value="RBOH/FRE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972:SF39">
        <property type="entry name" value="FAD-BINDING FR-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972">
        <property type="entry name" value="NADPH OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00466">
        <property type="entry name" value="GP91PHOX"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00052">
        <property type="entry name" value="Ferric_Reductase_Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01168">
        <property type="entry name" value="Ferric_reductase_subgroup_(FRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01169">
        <property type="entry name" value="NADPH_oxidase_subgroup_(NOX)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="179"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="214"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="10">
        <location>
            <begin position="235"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="316"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0007932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="553" mass="63161" checksum="048B1CD5C2306D77" modified="2023-09-13" version="1">MFKALETWTPRRYAFFITWFILHVILFIFGVLRVKLDANLSNLNVPLNYSLWIARGGGMCLIWDCSIILLPVCRNILRILRVSFLNKLIPIDENIWFHKITAYSILVCTTVHAVGHYVNFYKMDRLYREPGHSPEFGMSAAELLYKSPAGITGHIMLLCMVLMYTTAKQTGRNKSFEAFWYTHHLAFVMLGALMFHGIGCIVRDKFGNCRGYESYRYLAIGYTLYIIERFIRAFRARLDTRLVKAIQHPAGVIELQIQKPSFKYKPGQYLFLNVPDISNYEWHPFTITSSPFEDYVSVHIRQVGDWTRALGTRMGVEKEGGSGGRGNQAAGMKRPEKNTELVDDRGEEIRIRAGFSMPQVCIDGPFGAPTEDVFDHEIVVLVGSGIGVTPFASILRDIWYRANNNMPLKTKRIEFYWVCRDLASLKWFQSLLATIEQSMLHVKLKIHIYCTAVMKPDQHHNIALHLHDDYTGADTITGLQALTNFGRPNFGAIFSELRQGIMNGTYMPGATQELVVDVAVFFCGPGAMAKSLRKESRLQSKNGVRFSFRKEHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWC6</accession>
    <name>A0A9P6SWC6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_004432</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002260">
        <property type="protein sequence ID" value="KAG0007631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWC6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="BRCT" evidence="4">
        <location>
            <begin position="640"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="883"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="110"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="182"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="428"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="610"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="765"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="844"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="8"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="123"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="190"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="256"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="348"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="387"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="440"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="466"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="612"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="626"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="951"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0007631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="951" mass="104048" checksum="BAE8131945E5EAD0" modified="2023-09-13" version="1" fragment="single">MGNETQINSVPSSSSSSPSTSSNVSTASSLPYAASRESKKSRKPISIFDLPCPPKCAPPQDDKSFFDRMDSIEKALEEEDAGKIPKTLEAGPEIVVESLNKKRRRIQITETPLVVAPHPHPASSPSLSSSSSAQLLDSFSSVSSDTLPASEKAPESNEVTAPQPPAKKVRFREEIEYHFIESRPSPSIRRSSRLASVRRRSSRSDHAIENATELSPPMSSRILTPEMLYPEDDEKKFQDWLSGSTPPPPLSPFISQQMTTDTSGGQTPIMREKTQETELLADSQISNDLDSGQDESEDERQTHSPSPNYERDSWDWEESLPASELDISARNQGSQVRIGESDGEDRSEDQGENRSKGNNDGNVEISIDSDNESKNDNASRGYIGENSEINVRSSNTQLLERSCKSNTHATHASSESLIVLPGSLEIASVESSKESEGPADGFGGGNDGGSSGNNKDIFEITPISDPASSAKPSAKSNTKHNTKPPHTTAHTTLVEPLANANSSTGPIDISEMASASSSKALGRSKKGKDTTTSIAAIIGSRRKQNIVQKPPITGESQILTSSTETGNSTNTTQFPRGTIPVINLDEEDYAIGSNLETAKMVHLDQTIVPVGSTESSPTTKQMPMNNKERVETAKSEPPKSTPGPLSKLGLYVIPTNMDSRIFDITRKRVIDLGGSWLGPRVKTLATDPRAKPDVPDLDPEKTTHIVTALTSIEDVKRFLSVDEINLKISVVNREWLSDTIMYKTPMEPQSYALRKVQPIAPLTQVEDITPPPTQGRANREAPQEMPENQWFPKFKSMVTGNQIAFNDIIQGIQEGSLDDPDILDTDDDGIVDGDIEEPGKNIEIHAPEEGLNPNEAANPNRLSDDNQPELTPKMKRELVHENRCFRCKEVGHWANRCPQPKPKPKDDEVLLQIINSGKSEGKRRKILYQCQSPHVVGKKEEPKYNKAILEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWL9</accession>
    <name>A0A9P6SWL9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">cysteine synthase</fullName>
            <ecNumber evidence="4">2.5.1.47</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Cysteine synthase-like protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BGZ80_003525</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>O-acetyl-L-serine + hydrogen sulfide = L-cysteine + acetate</text>
            <dbReference type="Rhea" id="RHEA:14829"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:58340"/>
            <dbReference type="EC" id="2.5.1.47"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion outer membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cysteine synthase/cystathionine beta-synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.47" evidence="4"/>
    <dbReference type="EMBL" id="JAAAID010001936">
        <property type="protein sequence ID" value="KAG0008375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWL9"/>
    <dbReference type="OrthoDB" id="10259545at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004124">
        <property type="term" value="F:cysteine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01561">
        <property type="entry name" value="CBS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000049">
        <property type="entry name" value="Cysteine synthase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000096">
        <property type="entry name" value="Related to cysteine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050214">
        <property type="entry name" value="Cys_Synth/Cystath_Beta-Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10314">
        <property type="entry name" value="CYSTATHIONINE BETA-SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="Tryptophan synthase beta chain-like PALP" evidence="15">
        <location>
            <begin position="84"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00078545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0008375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="437" mass="47307" checksum="F5D22DB637F16DB1" modified="2023-09-13" version="1">MLESISDKNKHIAIGAALGIFFTLSTTAIVLATRGISSDPNRNSHSTSRRDNRRRSLINFSNDKLISSSPKADRSSSICDGVAGLIGNTPMMRIKSLSEATGCEILAKAEFLNPGGSTKDRVALSMINTAERDHILTPGNGSTIFEGTVGSTGISLAMMAKARGYNAWIVMPDDVALEKSQLLEKLGAHVEKVRPVSIVDKNQFVNLAKTRAQNFGKDEDGSESSNSQKTGFFADQFENLANFEAHFTTTGPEIYKQTGGNVDAIVMGAGTGGTLAGVAKYLKGLLPNLRVYLADPQGSGLFNKVKYNIMYSPTEKEGRRKRHQVDTVVEGVGINRLTRNFAMSEGLVDDAIRVTDQEAIDMARYLVHNEGLFIGSSSAVNCVSAVRIARELGPGHTIVTLLCDSGHRHLTKFWNDDYLTAQGLEVKDVVDSLDFIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWY8</accession>
    <name>A0A9P6SWY8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_002960</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001759">
        <property type="protein sequence ID" value="KAG0008873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030544">
        <property type="term" value="F:Hsp70 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058210">
        <property type="entry name" value="SACS/Nov_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052972">
        <property type="entry name" value="Sacsin_chaperone_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF047352">
        <property type="entry name" value="P_loop_sacsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15600">
        <property type="entry name" value="SACSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15600:SF42">
        <property type="entry name" value="SACSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25794">
        <property type="entry name" value="SACS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="1451"/>
            <end position="1532"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0008873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1670" mass="189277" checksum="24E0D674352D04EC" modified="2023-09-13" version="1">MKEALNHLPWILADGALYPVDRVALSMSLELTPHFVQIKLSGLDDFFIAMGVREAIGQADLQGIVSKIGSQYGKDEPLSAKDVEFVIKLLKGIAFEGVNESHDLLILTQDNRLCNILDVVYDNVGVVDDASNSEDINQTYTFANSQIIRSVAETLKIPMYSTSFWHDQRDLSFEPWAQEEDILVRIRNILNDYDPSSIFVEFLQNAADAGATKCSFMLDERKYGDNKVLSEKMAVWQGPALLIYNDAEFSEDDFNALCKLGEGSKREDSRKIGRHGVGFNSVYHFTDVPSVVSGSYIGFFDPLHEYLPELKTPNGYARQGGQRCKIVNLQGPAFSDQLEPYMESFGCDMKSHYKGTIFRIPLRMADNQEKTSRKSITNNIWELSQIRKMLRDWAEDGKLGMLFLDNIMNIEIIGVSDNPSDECNFSWSAVKSFANEKPHLNRALHKGNDPSNVTRMFDIRTSSSSTLMTESQRWLVHTDVEYPPDTLQAVKDLATTNRWRPCSGVAFPLNWPKNNSFIGKLFTHLPTPIMTGLPFHIHGGFALMSNRKGLAGGTDTMSSQFKWNEFMKRDCLPLTAVTAMEKLLIWQFWGLTVNSHKARDIGSAITAYYKYWPTNPRTDFESFVQKFSRSSHSHPVHPVLAGDPGVHARFMCGRDVVFPELDHPTIRIGNLICKYERTKGVGIGECSPEIQAQLRSDWKDPKLRFSAMDEDYIRNIIKEDPNFIPEKVMKNGEQRYSIDDVRWILEYTLRVILETKRKLSKVPVVPVIGLHLLPMMDNTWKPLGLFSPCYTATAEMRSLIKGEEYLIDESIFASAISTTLSSDMVPSLEQIFKKLSSDDTYGITQLPPTKFTSIFNSENPNGPTEDQRERLWRLLEKSEDFDAYGELPILKTLNGTMVPLKFYKNGIEISHLTYMARSNAETLSSLMVDLGLIVFDALQNYRNPSIIRVTEEATVSMILKSIAVSCATLPNSRVISTEEAEVLREMIKEGAYLSNPELESLGNLRIWSSWSAVDDNTTSHLIPARGSFFMEGEYSLEHLGDDSDVIRGTYRDHYGAMGARPLTVVTAAESRVMPRLLDNVLDCNEAQTKGAYIKMLLSIARVASIKKGGHRARNFLLSRRFILARDGTFHTTQELLDPSDSLLPVVFEGETSKFPDSQLWQRISASQKCSLFMLRDSRSTGMIRECALHVLDLTGIDSTTLPHPAKVPAEALIRHIYQNSDDISWMNPDWNIVPAEVASDSPYSMCVPEIPAFMSFSGLVDPSYRDVCWTQCAFFSENMKPSESFRARFPSVGKPKLRAVIQHLSVIVEDLSPKWVTLDDQLALKVSLFKVYKFLEDISKESGTEDAANLKSELAKLHVPFILNGDDKDPSLSESWSWPNQLMLDIDNDIEMHQVVHNKLKPYRGFLVAAGVEEMKDVEARIEVPEGRDQCYIGKLLLNCFESQDMLNGFMDVQFRFANGNQIFAHKVVLANSNERLSRQFTGLWAEHAVPDPSNPKVDLIDLSNVRESDETYEAFWGLIFYFYTNRLISTNGPPVLLFEQTTNQTHDDPWRDRVQYLMELLCLADQYQESRLKALIAAEIVHGKKAKHSNVFNIRKFAMLYSSNDIKGYCEKYLTANTSSVRTYLNGEIQVQRRLLMKLSGEGSIEKREEIGEYIKELEENLRELDSLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXM8</accession>
    <name>A0A9P6SXM8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Duf895 domain membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_001914</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001454">
        <property type="protein sequence ID" value="KAG0009942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXM8"/>
    <dbReference type="OrthoDB" id="196103at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010291">
        <property type="entry name" value="Ion_channel_UNC-93"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051617">
        <property type="entry name" value="UNC-93-like_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23294">
        <property type="entry name" value="ET TRANSLATION PRODUCT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23294:SF59">
        <property type="entry name" value="UNC93-LIKE PROTEIN C922.05C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05978">
        <property type="entry name" value="UNC-93"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="43"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="138"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="180"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="233"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="271"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="303"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="356"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="438"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0009942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="485" mass="53255" checksum="63CBAB9A75ABFCE1" modified="2023-09-13" version="1">MPRLSDPLVQIIILGFLCFCCPGMFNALQGTGAYGLAPKDSDIGNHASIALSLVFAISSLFAGALFNVVGHRALLIIGGFAYPLYISSFLAYAYIQSIAFVVVASCLLGVGAGWLWCAQGAMMMGYPEEGEKGMYFSIFWAIFNCGGVLGNIVPLAIQWNDPINDLGANTGDGGASTNSYIGYMSVMVVGMILSLFLLPSNKVIRRDGSHVIRIKYLSPITELKSVFYLFRDWRMLCLVPMFFTSNWVYTYQFTGVNALNFSPRSRNMNSMFYWLSQIIASILFGSFLDRAEWSRPKRARSGLILLAILLVGTWCGGIIFQSTFGPMNAIRNDNGVYVKNPADFHAIDLVRNPREYIGPFFLYIAYGCVDAMYQGYSYWLMGALTNDTSQAARFAGFYKFVQNLGSVLAPVVQTSVIGNGPSDGFNALHATGRGMGEIIVCVALVFTGVLGAIPVAFRAVKDHTFEIEEEINDELHELEVEDLKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXN4</accession>
    <name>A0A9P6SXN4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphoribulokinase/uridine kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_002386</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001587">
        <property type="protein sequence ID" value="KAG0009439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXN4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0009439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="257" mass="29702" checksum="5006646C39EC263D" modified="2023-09-13" version="1">MDDLYLPYKDQLTLSQRYPDNKMIEFRGLPGTHDIQLGSMTFHAFCTANQRVQSLSGNTQEGQGVPVKVPIPSYDKGLYSGRGDQIPRDQWPQAEAPFDVILFEGWSLGFKSIRNADQLSEIYQQHSTFPPYYLAKHSFSSLEMVNKSLEAYEKEWYSYLDIFVHLSTSSLSTIYKWRAEQERDLWASKGTGMTESQVEEFVSRFMPAYEVYLERLQRENVFKDDDVNSLPVPAIEGRHLRLDLDEERNLASSTLVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SY99</accession>
    <name>A0A9P6SY99_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_000925</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001203">
        <property type="protein sequence ID" value="KAG0011133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SY99"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="23"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0011133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="103" mass="10780" checksum="9572E5FDFB6FB18F" modified="2023-09-13" version="1">MAHHEPADKSALSPITTTPPSPSSGGSRSINYVNNNNKNNDNNNNTGCSNCSCNRQADDSHSAAFNLQGSIPEDVVVVETPTTTTTDYAPAIDLASQTVTTTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYV0</accession>
    <name>A0A9P6SYV0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_000049</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001002">
        <property type="protein sequence ID" value="KAG0012319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYV0"/>
    <dbReference type="OrthoDB" id="354826at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001664">
        <property type="term" value="F:G protein-coupled receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004703">
        <property type="term" value="F:G protein-coupled receptor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007186">
        <property type="term" value="P:G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009966">
        <property type="term" value="P:regulation of signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000354">
        <property type="entry name" value="AGC/YANK protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000469">
        <property type="entry name" value="Serine/threonine-protein kinase 32B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24355">
        <property type="entry name" value="G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24355:SF30">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE 32B ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="22"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="9">
        <location>
            <begin position="283"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="365"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="372"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="404"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="442"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="455"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="524"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="577"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="617"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="656"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0012319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="720" mass="80754" checksum="7EE9AF05B2BCC00F" modified="2023-09-13" version="1">MGAGCCKEEAIDFNSEIELSHFHLLRSVGKGAFGKVRVVQHKRTKEIYALKYINKAKCIRMRAIENIIQERRLLEEVEFPLICNLRYAFQDDENLFMVLDLMLGGDLRFHLERAGPMKEDAVRFYVAELALALDALHSRRVIHRDLKPDNILLDEHGHAHLTDFNIAVYFNPAKPLLSIAGSMAYMAPEVLLRKGYLETVDWWSLGVIAFELLFGKRPFRGKSNELLTNSILRDPLPFPDNVNDIVSANCIDVVSKLCERDISKRLGCTPDGLNGFKKHPWFEGIEWDMLVSKQAIPPFQPDSKRANFDATHELEELLMEDNPLKAKKRAQTSPETELSAEMQMMEDKFTVYDFSKVKRSTSLNRGRILRPTNDSRMNSGTLDGVVTRTTGRIDTPPIPPPKINRSESPSDRVGQDRYRPDEEYIGLTQSSYKRSPLGSPALNASSTPSGSVESPRFKTEEKAGYFELQDQPSHSSPQPKPKPKGVEIMTEAITMPSKSLPRPLQPLDNVTGLRIGSPRHYAYSLSSPSTTSPSSPSNQVQQSPLSSYTTPTTTQNSPATPQKSGQQFQPYRPETALFSSPDSRMPLSNVTDTGSLQDPTNIPISRRVVRGRESAGFTVNSMPASTSAPSNNPRLVSSNYVNGAFNPHQPLDTGADAQSYQKSWQYNEQISRPMSAYTTGAPGSNYQRRPSASSIRPDDRNMYRQQQLQQQQHTGYERSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZ68</accession>
    <name>A0A9P6SZ68_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_011199</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000872">
        <property type="protein sequence ID" value="KAG0013252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZ68"/>
    <dbReference type="OrthoDB" id="2448809at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040109763" evidence="2">
        <location>
            <begin position="21"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0013252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="132" mass="15152" checksum="5F134DA7D8A19652" modified="2023-09-13" version="1">MRFILSVLLASALLGAMATADKERRDVSTAVIAPEVPNLDLHTKESRSHHDKKAASKHLELHRKKASHSHNKKHAKRDLEGIRLHRKKAQHQQGSWTEEEKRHLSKTQDIKRSLGKQRRASQNGKKVQNKRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZR4</accession>
    <name>A0A9P6SZR4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_011259</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000885">
        <property type="protein sequence ID" value="KAG0013154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZR4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="72"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0013154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="97" mass="10019" checksum="461D0E68FF618A50" modified="2023-09-13" version="1" fragment="single">MLVNTAQGNVPRSRDGSASYHRRSVSCVASHDELSYFPIEVVEEEDAAAISTGNISSGSPSVHQADGTMTRSLSSNSSDSADSVVSVTSSSLGGKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZY1</accession>
    <name>A0A9P6SZY1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cytomegalovirus gh-receptor family</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_010380</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAPT1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000716">
        <property type="protein sequence ID" value="KAG0014539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZY1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008010">
        <property type="entry name" value="Tatp1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13317">
        <property type="entry name" value="TRANSMEMBRANE ANTERIOR POSTERIOR TRANSFORMATION PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13317:SF4">
        <property type="entry name" value="TRANSMEMBRANE ANTERIOR POSTERIOR TRANSFORMATION PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05346">
        <property type="entry name" value="DUF747"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="309"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="436"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="543"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="628"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="707"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="740"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="135"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="179"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="49"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="67"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="89"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="201"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0014539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="852" mass="93938" checksum="9D1555F564F059D3" modified="2023-09-13" version="1">MSAPTPSSSSQQQQHLQKPQQPQQQELQLQQQQQQQHSQQHQQSPNGPARKHGKKKSRNSWKAGFKTTPSSPSPSTIDTRPSILSEMTANANHISNNANNVNNNYNTPLSNSHPKPSRTIDIPQVGLERENRENGIPRSLHHGTLESSAHEGTGPSVGATSPRKNEFLQSLDIQLSKLQRDEERSQQTSPAGGAKDTKHPSASSSASKAGGATKVFERELSQLLKAPVPALPGSETSQDDLKLKDLLGSISPSNNPSVSLWDYLKEELTAADFETTQELKRERVANFLSVPIAFEKMIVFGYFVCLDSFLYTFTILPARFVLATVALFRYILSRTWFSKSSERIRLKSSQKCDLIKVTLVVVACTILQSVDASRTYHFIRGQNAMKLYAIFNCLEIFDRLCCSFGQDILDSLFSKSTLGSHPPKATLTASRHARPITFVILAILYILAHTLVLFYQMVTLNVAVNSYSNALLTLLISNQFVEIKGSVFKKFEKENLFQLSCSDIVERFQLSVFVAIITIRNLVEISASPPSPFSVYPQSFVPLFSSMTAVARLLTPCFLVLGCETLVDWLKHAFITKFNQIRPSVYGRFVDILSRDLVVGSPARLAGRDNQRQMFVDQSPMVSRRIGLAALPLACLVISVTTQTLQMVLSTNEMTRAPVVMAETIVASTVSFDKISLDWTMPAIDFSSGLSVASSDMVDALASFFKFAWGAFGQGSVALGHLIVAWARQAGISQELGRKVMEYAVIGLACLATYACLVALKLLIGINLLGFSHHRYLTMESREEVERQTDQMMRESNAALEEKAASAAVSGMLDGRGGGHGNGDAYVLGGEKRVIHGLDTIDRYTLFKSRIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZZ8</accession>
    <name>A0A9P6SZZ8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">60S ribosomal protein L12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">RPL12</name>
        <name evidence="7" type="ORF">BGZ80_010095</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000668">
        <property type="protein sequence ID" value="KAG0015012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZZ8"/>
    <dbReference type="OrthoDB" id="1478556at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00349">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.250:FF:000002">
        <property type="entry name" value="60S ribosomal protein L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1550.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.250">
        <property type="entry name" value="Ribosomal protein L11, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1550.10">
        <property type="entry name" value="Ribosomal protein L11/L12, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00736">
        <property type="entry name" value="Ribosomal_uL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000911">
        <property type="entry name" value="Ribosomal_uL11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020783">
        <property type="entry name" value="Ribosomal_uL11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036769">
        <property type="entry name" value="Ribosomal_uL11_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020785">
        <property type="entry name" value="Ribosomal_uL11_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020784">
        <property type="entry name" value="Ribosomal_uL11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036796">
        <property type="entry name" value="Ribosomal_uL11_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11661">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11661:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00298">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03946">
        <property type="entry name" value="Ribosomal_L11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00649">
        <property type="entry name" value="RL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54747">
        <property type="entry name" value="Ribosomal L11/L12e N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46906">
        <property type="entry name" value="Ribosomal protein L11, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00359">
        <property type="entry name" value="RIBOSOMAL_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL11 N-terminal" evidence="6">
        <location>
            <begin position="13"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL11 C-terminal" evidence="5">
        <location>
            <begin position="74"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0015012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="165" mass="17550" checksum="0C1504D8A15474FE" modified="2023-09-13" version="1">MPPKLDPNEIKIIYLRATGGEVGASSALAPKIGPLGLAPKKVGEDIAKATQDWKGLRVTVQLTIQNRQAAVSVVPSASSLVIKALKEAPRDRKKEKNIKHNGNITLDEVIEIARIMRHKSLARELSGTVKEILGTAFSVGCTVDGQSPKDLGDAIDAGEVEIPEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0C9</accession>
    <name>A0A9P6T0C9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="4">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">BGZ80_009793</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="4"/>
    <dbReference type="EMBL" id="JAAAID010000618">
        <property type="protein sequence ID" value="KAG0015542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0C9"/>
    <dbReference type="OrthoDB" id="248923at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06609">
        <property type="entry name" value="STKc_MST3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000411">
        <property type="entry name" value="Probable Ste20-like kinase Don3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050629">
        <property type="entry name" value="STE20/SPS1-PAK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48012:SF10">
        <property type="entry name" value="FI20177P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48012">
        <property type="entry name" value="STERILE20-LIKE KINASE, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="17" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0418">Kinase</keyword>
    <keyword evidence="13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="19">
        <location>
            <begin position="10"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="501"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="17">
        <location>
            <begin position="36"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="506"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAG0015542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="563" mass="61616" checksum="ACB4A0139BCC67AA" modified="2023-09-13" version="1">MMRSDPEEEYTLLEKIGTGSFGTVYKAIHNVSKEVVAIKQINLEDSEEDISEIQQEIALLSQCDSEFITKYYGSCVKGFKLWIVMEYLAGGSCLDLLKPGPFSEDHVAVVLRELLLGLDYLHSEGKIHRDIKAANVLLSGAGDVKLADFGVAAQLSHQKSKRNTFVGTPFWMAPEVIRQAGYDSKADIWSLGITAIELAKGEPPLAEYHPMRVLFLIPKAKPPSLEGDFSRAFKEFVELCLIKNPKERPTARDLLKHRFIKMAKRKSDLQELVERYDVWKLAAHQRAASSLTKTFSTFNTNDEDLPWDFGTIRIPGLASTRSTVRRHPVNAQSTVRAPKHTQDMGSVVNLANLKIEGGELQSLTIRSVETDKPGPGDMTIEDGFETIKAAPATKKVVTEDVFEGSPQAQAGRQLAKVALLPVLSNLKSGEHSAEDLEAISVLEHGIADLNDINPSLLLAFFTQALTQIKGDSDLLNQMETHGGAAVTEAIGALANGRLLSDEEESVSSSSTGSTDMSAAEPDTKTVEPDAPATAETRSPASPVAEALYARWIEHLRSKWPIVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1L7</accession>
    <name>A0A9P6T1L7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008478</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000460">
        <property type="protein sequence ID" value="KAG0017261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1L7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0017261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="66" mass="7178" checksum="0C5088F28824BEC3" modified="2023-09-13" version="1">MTTAWITGKPAPVGKRSIALTLYTIAVNACDMVSVNLFSGQDAQRFIRGFWILFGALLATIVLSIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T251</accession>
    <name>A0A9P6T251_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">COP9 signalosome complex subunit 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">COPS8</name>
        <name evidence="7" type="ORF">BGZ80_005927</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000292">
        <property type="protein sequence ID" value="KAG0019369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T251"/>
    <dbReference type="OrthoDB" id="5351233at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008180">
        <property type="term" value="C:COP9 signalosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010387">
        <property type="term" value="P:COP9 signalosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000338">
        <property type="term" value="P:protein deneddylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033205">
        <property type="entry name" value="COP9_CSN8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033464">
        <property type="entry name" value="CSN8_PSD8_EIF3K"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13339">
        <property type="entry name" value="COP9 SIGNALOSOME COMPLEX SUBUNIT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13339:SF0">
        <property type="entry name" value="COP9 SIGNALOSOME COMPLEX SUBUNIT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10075">
        <property type="entry name" value="CSN8_PSD8_EIF3K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0736">Signalosome</keyword>
    <feature type="domain" description="CSN8/PSMD8/EIF3K" evidence="6">
        <location>
            <begin position="47"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF10075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0019369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="215" mass="24260" checksum="3E29B7394C69564E" modified="2023-09-13" version="1">MTTRAQQIIEQADSCLKAGRYEELIPLYEQLEFQVSAIEIDAVPLNTIYEPLLASYLVANDLHSARGLVDRIPEEYKTQAPQLATLIQVLDMMRQWERQNGKLKDIYNLLHQSRWDTSLAPLMALLQDSIQERELNILAKAYTSLPVQLAASRVWVEEDAAAEQLVATLGWRYDASAGLLYPKAQEPIPNRAIGLQEFGQLADVVAHLEVKQESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T273</accession>
    <name>A0A9P6T273_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Cyclin-dependent kinase 8</fullName>
            <ecNumber evidence="4">2.7.11.22</ecNumber>
            <ecNumber evidence="3">2.7.11.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">SSN3</name>
        <name evidence="19" type="ORF">BGZ80_005557</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10216"/>
            <dbReference type="Rhea" id="RHEA-COMP:11321"/>
            <dbReference type="Rhea" id="RHEA-COMP:11322"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43176"/>
            <dbReference type="ChEBI" id="CHEBI:68546"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.23"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.22" evidence="4"/>
    <dbReference type="EC" id="2.7.11.23" evidence="3"/>
    <dbReference type="EMBL" id="JAAAID010000274">
        <property type="protein sequence ID" value="KAG0019594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T273"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008353">
        <property type="term" value="F:RNA polymerase II CTD heptapeptide repeat kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07842">
        <property type="entry name" value="STKc_CDK8_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000408">
        <property type="entry name" value="Serine/threonine-protein kinase SSN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF495">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 19" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0678">Repressor</keyword>
    <keyword evidence="6" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="18">
        <location>
            <begin position="21"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="355"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="376"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00041823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00049280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAG0019594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="388" mass="44525" checksum="F6D7E558422C7926" modified="2023-09-13" version="1">MSMTEYKAKRDSCRQKIASKYDILGFISSGTYGRVYKAKSKNKDDGKEYAIKKFKPDKEGEAATYIGISQSACREIALCRELHHENIVGLQEVLLEDKSIHMVFEYAEHDLLQIIGFHSHPERKFMSEYTIKSFLWQLLNGVAYLHANWVMHRDLKPANILVTANGVVKVGDLGLARLFYKPLQPLFNGDKVVVTIWYRAPELLLGSRHYTKAIDIWAIGCIFAELITLRPIFKGEEAKVENKKTVPFQKNQLQKIFDILGNPTKERWPTIDQQPEYPNLSSFRQTPNILRSLYQSWPIKSDQGCNLLAAMLEYDPAKRITAEEALNHPYFQEDPKPGMDSFAGQPVEFPLRRITNEDKDMRATAPVQKAHPVPAVKDDRTTKRPRVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2N1</accession>
    <name>A0A9P6T2N1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">6,7-dimethyl-8-ribityllumazine synthase</fullName>
            <shortName evidence="7">DMRL synthase</shortName>
            <ecNumber evidence="3 7">2.5.1.78</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_004131</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>(2S)-2-hydroxy-3-oxobutyl phosphate + 5-amino-6-(D-ribitylamino)uracil = 6,7-dimethyl-8-(1-D-ribityl)lumazine + phosphate + 2 H2O + H(+)</text>
            <dbReference type="Rhea" id="RHEA:26152"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15934"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58201"/>
            <dbReference type="ChEBI" id="CHEBI:58830"/>
            <dbReference type="EC" id="2.5.1.78"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Cofactor biosynthesis; riboflavin biosynthesis; riboflavin from 2-hydroxy-3-oxobutyl phosphate and 5-amino-6-(D-ribitylamino)uracil: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the DMRL synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.78" evidence="3 7"/>
    <dbReference type="EMBL" id="JAAAID010000214">
        <property type="protein sequence ID" value="KAG0020473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2N1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009349">
        <property type="term" value="C:riboflavin synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000906">
        <property type="term" value="F:6,7-dimethyl-8-ribityllumazine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09209">
        <property type="entry name" value="Lumazine_synthase-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.960">
        <property type="entry name" value="Lumazine/riboflavin synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00178">
        <property type="entry name" value="Lumazine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034964">
        <property type="entry name" value="LS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002180">
        <property type="entry name" value="LS/RS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036467">
        <property type="entry name" value="LS/RS_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00114">
        <property type="entry name" value="lumazine-synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21058:SF0">
        <property type="entry name" value="6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21058">
        <property type="entry name" value="6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE DMRL SYNTHASE LUMAZINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00885">
        <property type="entry name" value="DMRL_synthase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52121">
        <property type="entry name" value="Lumazine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0686">Riboflavin biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0020473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="209" mass="22121" checksum="02ACA87637D17BC7" modified="2023-09-13" version="1">MIDDFHKGLEPSTVSQDGSNLRILIVHTRWNSAIVQGLVSGAKKAMIEQHNVKPENIVIESVPGAYELPFAAKKLIEVSQIRAAEGANDLMGNVNLLDGLNLSSSAAPASTVSANPAGSKQAFDAVICIGVLIKGSTMHFEYICEAVTQGIMRVGLDSGLPVIFGVLTCLNEEQALSRAGMDKEGKGHNHGLDWGSGAVEMALLKSRTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3D7</accession>
    <name>A0A9P6T3D7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">[histone H3]-dimethyl-L-lysine(36) demethylase</fullName>
            <ecNumber evidence="4">1.14.11.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">[Histone-H3]-lysine-36 demethylase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="primary">JHD1</name>
        <name evidence="17" type="ORF">BGZ80_000738</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>N(6),N(6)-dimethyl-L-lysyl(36)-[histone H3] + 2 2-oxoglutarate + 2 O2 = L-lysyl(36)-[histone H3] + 2 formaldehyde + 2 succinate + 2 CO2</text>
            <dbReference type="Rhea" id="RHEA:42032"/>
            <dbReference type="Rhea" id="RHEA-COMP:9785"/>
            <dbReference type="Rhea" id="RHEA-COMP:9787"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:16842"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:61976"/>
            <dbReference type="EC" id="1.14.11.27"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the JHDM1 histone demethylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.11.27" evidence="4"/>
    <dbReference type="EMBL" id="JAAAID010000116">
        <property type="protein sequence ID" value="KAG0022225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3D7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140680">
        <property type="term" value="F:histone H3K36me/H3K36me2 demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041070">
        <property type="entry name" value="JHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050690">
        <property type="entry name" value="JHDM1_Histone_Demethylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23123">
        <property type="entry name" value="PHD/F-BOX CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17811">
        <property type="entry name" value="JHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02373">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="7" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0804">Transcription</keyword>
    <keyword evidence="10" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="JmjC" evidence="16">
        <location>
            <begin position="174"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="441"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="703"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="446"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="15">
        <location>
            <begin position="468"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="479"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="496"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="15">
        <location>
            <begin position="525"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="553"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="593"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="15">
        <location>
            <begin position="612"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="626"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="709"/>
            <end position="730"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00031083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0022225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="745" mass="83562" checksum="58C871FF2BE26571" modified="2023-09-13" version="1">MSLKLLTNTIAQIVYPKLVLVPVCSDSAAVLIVAHLRKSSRRTGKINYADLVNGIVSHASKWRVLLESHQFLPDKFERLEGKDMTTEWLRTTGFKYPVVVKKDQDGTTNGLDMKMPSVGLTVDDVRDAVGPETPVEVIDVATQSELPDWNMASWADYFKAEDKERVYNVISLEISGTPLADQVQRPKVVRELDWIENFWPKALMATEFPKVQLYCLMSVKDSFTDFHIDFAGSSVFYHILSGSKTFFFVEPTSTHLRKYAKWSSSADQSTTFFGDEVAGKCYKVELQQGDTMLIPAGWIHAVYTPSSSVVIGGNFIHSLHIPMQYRVCDIEIETNVSPKFRFPYFEKLNWFVAYGCMERGLEYLSSLSKAELRGILALTVHLYNRQRSLKRDPQLIKEERHMIRASVPSEVAGYANGGQAGLLRDLNHLVCTVLEGSNSDNVTRTPIEHALRVPSEEEEREEDEKAMKNKPRIKLRIKLSSTTSSTNSGDEESSHGEQQVPTSATTSAPTKLKFKLPSISSIKHASSKSSKKSKRVRKHKSDMDPEVYGSGSDLDDDEELDQQLTSDEEWTEFESQIDEGFDEAKEDYEEIDDGGRLDLRSSDSEYDEESKHRTKRAAPRQRKNSGSKTPTTAKSPTIAAMPRSKQSSSETVYFGDDGEFDHPPQPVRRPSKRESDDDDEEEVVLGLGKKRKLTPMQFSSLITSSSPVSFAKPTTSTSTSSAAKKKAAIGGTAKDRIKSLLLKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3U3</accession>
    <name>A0A9P6T3U3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Lanosterol synthase (Oxidosqualene--lanosterol cyclase)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ERG7_1</name>
        <name evidence="4" type="ORF">BGZ80_001932</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the terpene cyclase/mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000146">
        <property type="protein sequence ID" value="KAG0021673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3U3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000250">
        <property type="term" value="F:lanosterol synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006695">
        <property type="term" value="P:cholesterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016104">
        <property type="term" value="P:triterpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032696">
        <property type="entry name" value="SQ_cyclase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018333">
        <property type="entry name" value="Squalene_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11764:SF20">
        <property type="entry name" value="LANOSTEROL SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11764">
        <property type="entry name" value="TERPENE CYCLASE/MUTASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13243">
        <property type="entry name" value="SQHop_cyclase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="Terpenoid cyclases/Protein prenyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Squalene cyclase C-terminal" evidence="3">
        <location>
            <begin position="2"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0021673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="95" mass="10956" checksum="F0194A66F0158F97" modified="2023-09-13" version="1" fragment="single">SCEQHKYVEHENSQVVQTSWALMALMAAKCPDHDAIKRGIHLFMSRQQPDGQWKQEAIEGIFNHSCSISYPNYKHIFTIWALGRYAKMYGDVAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T4A8</accession>
    <name>A0A9P6T4A8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="21">General transcription and DNA repair factor IIH</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">BGZ80_007844</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the GTF2H2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000041">
        <property type="protein sequence ID" value="KAG0023822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T4A8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000439">
        <property type="term" value="C:transcription factor TFIIH core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005675">
        <property type="term" value="C:transcription factor TFIIH holo complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01453">
        <property type="entry name" value="vWA_transcription_factor_IIH_type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.410:FF:000015">
        <property type="entry name" value="General transcription factor IIH subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.60:FF:000014">
        <property type="entry name" value="Protein hob3, variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004148">
        <property type="entry name" value="BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046349">
        <property type="entry name" value="C1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007198">
        <property type="entry name" value="Ssl1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004595">
        <property type="entry name" value="TFIIH_C1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012170">
        <property type="entry name" value="TFIIH_SSL1/p44"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00622">
        <property type="entry name" value="ssl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12695">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12695:SF2">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03114">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07975">
        <property type="entry name" value="C1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04056">
        <property type="entry name" value="Ssl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00721">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01047">
        <property type="entry name" value="C1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57889">
        <property type="entry name" value="Cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51021">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="11" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0804">Transcription</keyword>
    <keyword evidence="9" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 14" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="VWFA" evidence="17">
        <location>
            <begin position="82"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="16">
        <location>
            <begin position="381"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="domain" description="BAR" evidence="18">
        <location>
            <begin position="441"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="456"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAG0023822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="21">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="681" mass="75677" checksum="21648B338EABC82A" modified="2023-09-13" version="1">MATNGRRQVDEDDDDIIDVDDSTLQTNQANYAWEEEYKRSWDVLQEDEHGSLAGVVNSLQQAAKRKRQLRDTDPIQRGIIRHLFIIIDLSSAMQEKDLRPSRLSLTFTYLEAFIAEYFDQNPISQIGLIGTKDGLAEKLSELSGNPTEHIRALKTKRQEVGGEPSLQNALELARSSLVHVPAHGSREILVIMGSLTTTDPGNIHDTIAQLTQDNIRASVIALAAEVQVLKFLSTQTKGTFGVAMNEGHYRDLLFEVIPPTAITTSKASSNLVQMGFPSRSNEAAATLCACHGKLTLGGYICPRCNSKLCDIPTECDVCTLTLVSSPLLARSYHHLFPVENFIEVAWKDAAATTACFSCQKSFLSPHKVSPQLQATTDAGRYQCKVCEKTFCADCDLFIHDVLHNCPGCLSQPRRNTSGGPLNANSGPAGFKKNLNRATTSVLSKTGNMDRTTDHEFEEEERRFKSLEQKVEKLHKEANGYASAVRNMTGSQLKIASTIEQFYDEGAPMGIYGIKYKEAVAKLEQQAQDEVDAGYRTTVLEPIGRYSAYFPEVNEAVRRRNKKLMDYDAARSKVRKLVEKPSEDSTKLPRAEHEANTLREMYETMNAQLTSELPKIIDSRVAYLDPSFEAVVKSQLSFSQDAHNTLEGLRQFFPPESEGYELEEAAEGILAQMRELSICGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T4M4</accession>
    <name>A0A9P6T4M4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Thymidylate kinase</fullName>
            <ecNumber evidence="3">2.7.4.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_004777</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Pyrimidine metabolism; dTTP biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the thymidylate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.9" evidence="3"/>
    <dbReference type="EMBL" id="JAAAID010000024">
        <property type="protein sequence ID" value="KAG0024263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T4M4"/>
    <dbReference type="OrthoDB" id="425602at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004798">
        <property type="term" value="F:dTMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004550">
        <property type="term" value="F:nucleoside diphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006233">
        <property type="term" value="P:dTDP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006235">
        <property type="term" value="P:dTTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006227">
        <property type="term" value="P:dUDP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01672">
        <property type="entry name" value="TMPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000679">
        <property type="entry name" value="Thymidylate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00165">
        <property type="entry name" value="Thymidylate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039430">
        <property type="entry name" value="Thymidylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018095">
        <property type="entry name" value="Thymidylate_kin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018094">
        <property type="entry name" value="Thymidylate_kinase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00041">
        <property type="entry name" value="DTMP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10344">
        <property type="entry name" value="THYMIDYLATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10344:SF1">
        <property type="entry name" value="THYMIDYLATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02223">
        <property type="entry name" value="Thymidylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01331">
        <property type="entry name" value="THYMIDYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thymidylate kinase-like" evidence="10">
        <location>
            <begin position="9"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0024263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="216" mass="24635" checksum="5E097DAD606B7D98" modified="2023-09-13" version="1">MARGRFILLEGCDRAGKSTQCSMLVSALKARGHAVELCKFPDRTTTIGKMIHAYLTNAQELDDKAVHLLFSANRWEAMQSIRRKLLSGTHLVVDRYAYSGVAFSTAKGLDLTWCKNPDRGLIRPDLTFFLDLPTSEAERRGGFGEERYEKRELQEKVRDVFLQLQSKEWVMIDACKSVEAMHHEILKETEHKIQVAEADAKLAEEDDVLVEDMFQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MCW0</accession>
    <name>A0A9P6MCW0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008506</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004625">
        <property type="protein sequence ID" value="KAF9992558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MCW0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="86"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9992558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="110" mass="12065" checksum="3428EC6643A9E3D3" modified="2023-09-13" version="1" fragment="single">MENSENIERIFGGTVRDDDLRDNEKADILNAGCGIIKESRLLAEIRNETLRLQTMAYFMLISSTLVMNDQAISVLNAADKTPQYTPSPKSPCSSSSRSSSSRSSSSRNSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MDD2</accession>
    <name>A0A9P6MDD2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NmrA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_008252</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NmrA-type oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004415">
        <property type="protein sequence ID" value="KAF9993167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MDD2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05251">
        <property type="entry name" value="NmrA_like_SDR_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051164">
        <property type="entry name" value="NmrA-like_oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748">
        <property type="entry name" value="NITROGEN METABOLITE REPRESSION PROTEIN NMRA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748:SF11">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="3">
        <location>
            <begin position="2"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9993167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="264" mass="28830" checksum="CC8DDCEB85AA946E" modified="2023-09-13" version="1" fragment="single">MSKILVVFGATGQQGGSIVKYVINDPELSKQFKVRGVTRDPSKPAAITLQQKGVEVVKGDFDDSESVKQAVQGAHTVFVATTTVYDEQIRSREYAQGKTVVDSAVAAGAQYFIFSTQPNTTKISGGKYQHVDHFDVKYDIEQYIRAQPLKSAFFAPGSFMQNFTHAMAPRPVGDGTYAISNVVAPQTKFPFIDINDTGKYVGAILAEPEKYEGTIFSAATALYSLEEAAEIISKVTGKTVRYKQLPIEVFKSFVPPVAAEHLVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ME03</accession>
    <name>A0A9P6ME03_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007940</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004173">
        <property type="protein sequence ID" value="KAF9994033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ME03"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9994033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="87" mass="9467" checksum="FDA57689CBF860F3" modified="2023-09-13" version="1" fragment="single">MVYKWLVVVVVIGIEQNGLVVDVVVVAIAYRVRRSVEDEFPGRLAPAGACERLFRALLTSRLPTDPLFVAALTASSTPWTSGSRPLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MED2</accession>
    <name>A0A9P6MED2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007828</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the lcsJ thioesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004087">
        <property type="protein sequence ID" value="KAF9994364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MED2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051490">
        <property type="entry name" value="THEM6_lcsJ_thioesterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12475">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12475:SF4">
        <property type="entry name" value="PROTEIN THEM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13279">
        <property type="entry name" value="4HBT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9994364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="167" mass="19052" checksum="934D7CD2795F4DFB" modified="2023-09-13" version="1" fragment="single">SYGKNCDYARVKYVTSLLGPSVLPLHPMRRIAFALGGNQMWFKKEITLFQSYEIRTRLLTWNRKWFVIEHRMYTPSRKCSRGENEQKLCAIGISKFVLKHAAGSLKGKTIPFLDALEMVGHDVSELRALEANSDNGNVVLWPKDRLEFKSFTGWTDRAASVGNALEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MEH0</accession>
    <name>A0A9P6MEH0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Condensation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004059">
        <property type="protein sequence ID" value="KAF9994466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MEH0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043041">
        <property type="term" value="P:amino acid activation for nonribosomal peptide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19544">
        <property type="entry name" value="E-C_NRPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensation_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF1">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Condensation" evidence="1">
        <location>
            <begin position="9"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9994466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="412" mass="45795" checksum="D426B6A939C6F08E" modified="2023-09-13" version="1" fragment="single">MWENLSVSAQVVLRHAPMSVTEISLDSADGSTLDQMTKLFDPRSYRIDLTQAPLIRFAIAQNTDGTWIAVQLMHHIIGDHSTMEVMAFEIDILLKSQDDSLLLAQPFRNLIAKTRSSASFETHEQFFTNMLGEIDTPALPYGHFDVHNDDTEVHESQRVVAIDLNNRLRSHAKRMGVGLASLCHLAWAQVISRTSGQERVVFGTVLFGRMQGGSGTDQAMGLYINTLPLRIDVEGASVEESVRQTQASLAALLEHEHAPLAIAQRCSSIPAGSPVFSAMLNCRHHSDASNNFSSIAGVVFHDEKQRTTFPFVMNVDDLGSGLSLTAQVVYPFEASRICAYMEQALHSLADALDWSPNMPVRKLEILPAEEREMLVKSWNTIESTFPDHHCIHNLFEDQVEQSPDSIAIVFQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MF50</accession>
    <name>A0A9P6MF50_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Signal transducing kinase of the PAK</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">STE20_3</name>
        <name evidence="8" type="ORF">BGZ80_007382</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003764">
        <property type="protein sequence ID" value="KAF9995958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MF50"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06614">
        <property type="entry name" value="STKc_PAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000385">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051931">
        <property type="entry name" value="PAK3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45832">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE SAMKA-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45832:SF22">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE SAMKA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 4 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="174"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="39"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="60"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="77"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="128"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="141"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9995958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="375" mass="40939" checksum="E43570B0DD927A48" modified="2023-09-13" version="1" fragment="single">QQQQQQQQQQQQQHPSSKGDRSSHQAPPLAPRPVYESPRLPPNPPPVKKPSVPRPADVAPIERQEPLEKIDTEPSPATAPLPPPPPPPPVAAALPPAPAPKVPPPKPKKIPNHQGNTVVSPPPPKPTPASGSNGTSGTGTKLREKKADKDAVSSQEVIRRLQAICTDADPTKLYRNLVKIGQGASGGVYTAYQNGTNLSVAIKQMNLEQQPKKDLIINEILVMKASSHKNIVNYIDSFLHRGDLWVVMEYMEGGSLTEVVTTNEMADPQIGAVCRETLMGLEHLHSQGVIHRDIKSDNVLLALNGDIKLTDFGFCAQLKESQGKRTTMVGTPYWMAPEVVTRKEYGPKVDIWSLGIMAIEMLEGEPPYLNENPLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MFI0</accession>
    <name>A0A9P6MFI0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007068</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003559">
        <property type="protein sequence ID" value="KAF9997149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MFI0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="373"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="212"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9997149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="504" mass="57046" checksum="CB99CDDF4018FE5A" modified="2023-09-13" version="1" fragment="single">MLRPAYQPVTPPGESLHPEKTSPIAVAKVHPDKITPSVSLEAAIITGSPQNIHNSPHNSNGSNMSNASKDTPMESVQRTEVKRSTNPFENARAPQVDLISFENVRGSPVDVNRASPFENARGSSIEMNRALSLENLRGSPEINKAAIIFENSRSSTIDLGKPTPFEHARNSPMMDVHSGSPFEHSKASPLDIGRGSPFDLPKGPFFEPKKVSPNNNNNNNNNNSNDTIENNSANSGDSNHKHSNNPFLKDMVHQQQSQMLIDIQQDMPVPQAINMTAPLIPLGLQNITGPILPPPQHFQQIQQQHQALAQQMLQNHQQLHQQFQQQQQPQQVQYVQQMRVQRVYGPQQQQQQQQQPQVQPQLPQIQRLHIQQVQQQQQQQSPPQLQQQQPPLQQQQQRQQVQPQPAPQQLQQQQPQQQQPQQQQPQQQQPQQQQPQQQQPQQQQRVVFEQVRAVLPIDDRVSPDAAGKGFETIERHVDENLEDETEETLNARIKADIVMLCQER</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MGZ9</accession>
    <name>A0A9P6MGZ9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DEP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_006595</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003265">
        <property type="protein sequence ID" value="KAF9999290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MGZ9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04371">
        <property type="entry name" value="DEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000591">
        <property type="entry name" value="DEP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058855">
        <property type="entry name" value="RGS1/SST2-like_Fungal-DR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16206">
        <property type="entry name" value="DEP DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16206:SF4">
        <property type="entry name" value="PROTEIN LET-99"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00610">
        <property type="entry name" value="DEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25889">
        <property type="entry name" value="WHD_Fungal_DR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00049">
        <property type="entry name" value="DEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50186">
        <property type="entry name" value="DEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEP" evidence="2">
        <location>
            <begin position="211"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="188"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9999290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="316" mass="35411" checksum="3248B2D94D5F6EC4" modified="2023-09-13" version="1" fragment="single">MKITTSGRAYAKDIFDLFSTLMISLPIENHKIFIKSYPNSFTAEDAIANLGGLQFIQANHDADPNDPTRIITRVVTTQFSLSRDMAKNLCQTFMDARLFECATDPGKKEFQNKGIYQVTGKGAHIVEKFVHRNSLSVEETRHITANATPRILFLERAENEDAVVLNQMTVDAIFKRFAGLKPNVMVRSSDSPGSASPLSPGRDRTQTSVDRCKGIEVKDQHHNYAIYKHTFYGKAAAEWLLDYTTVISRDEATRIAQEMVSVRYIEQVGDENKNGPAAFKTGNSSLYHFTEAGRAVLGWESLIRSRGSSVNTDWMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MHP4</accession>
    <name>A0A9P6MHP4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Velvet domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_006390</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003154">
        <property type="protein sequence ID" value="KAG0000289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MHP4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030435">
        <property type="term" value="P:sporulation resulting in formation of a cellular spore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.3960">
        <property type="entry name" value="Velvet domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021740">
        <property type="entry name" value="Velvet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037525">
        <property type="entry name" value="Velvet_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038491">
        <property type="entry name" value="Velvet_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33572:SF17">
        <property type="entry name" value="SEXUAL DEVELOPMENT REGULATOR VELC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33572">
        <property type="entry name" value="SPORE DEVELOPMENT REGULATOR VOSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11754">
        <property type="entry name" value="Velvet"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51821">
        <property type="entry name" value="VELVET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0749">Sporulation</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Velvet" evidence="7">
        <location>
            <begin position="4"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="27"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="86"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="105"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0000289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="339" mass="36847" checksum="62D4AC1167A6E06E" modified="2023-09-13" version="1">MINFRIISSPARIKIVQQPLHARMCGFGEKDRRPVDPPPIVQLLLDEDHEQHPTKRMQRSAAKKSAGDSKDKPEDNKEDKSGGKEGEDETDQLEEDGNEEKQTDGTATGKAAAKGRAGSLQKQDLQDAASGTGSSPSLGKRSRPSSNSKSKAKRSGTADDDDGEKSHSDHSQSGSDDEGDDDNNQHVDGNLQEQDPLFVLHVSLWSADGKEVRNMIATPGQSEPPKLTRILMGSLVVSPILLNNPEGVPGWYFSFPDLSIRTEGVYTLKFSLMRFGSFDFLSNDGGHASTLVAEEISEPFTNQPNCQKPLRSKASKSLFVMICVPAKPTETTENMGGEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MK71</accession>
    <name>A0A9P6MK71_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_005617</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MUB1/samB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002768">
        <property type="protein sequence ID" value="KAG0004423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MK71"/>
    <dbReference type="OrthoDB" id="5594178at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990304">
        <property type="term" value="C:MUB1-RAD6-UBR2 ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007163">
        <property type="term" value="P:establishment or maintenance of cell polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051664">
        <property type="entry name" value="MYND-type_zinc_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47442">
        <property type="entry name" value="MYND-TYPE ZINC FINGER PROTEIN MUB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47442:SF1">
        <property type="entry name" value="MYND-TYPE ZINC FINGER PROTEIN MUB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="9">
        <location>
            <begin position="359"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="142"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="237"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="411"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="458"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="544"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="720"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="855"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="144"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="183"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="255"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="420"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="459"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="505"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="544"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="575"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="605"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="621"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="720"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="744"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="780"/>
            <end position="792"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0004423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="898" mass="99515" checksum="CB57E020E5AE7125" modified="2023-09-13" version="1">MREPNFSFPNQNRAAICITSSIYDRRALDCTDYIPIINTLTNLAYLTGSTPTIREFITRDGGLERLVTILKTTKVNDRKNGLKWTLAFQCVVNIGVRGTEHIRKRVVQAGMVPVIVHVLESFFTVLKSVNDENERRKLLRRAETAQQNSQTMITDGDHSTDSQPFTAPMTEEPEQLQGTGLDTSNNSSSSLSSSSITAATLAAPSTTAASITVGSVEPSTVNLAPQPTTIFQNSLFHHNPLDDAQGPSAMPAAQELSQAHTNPDNTRSIPMDNGDGRPQQIFYREDDILHSLQLLAYLSKYPSLRSSFHTDSGSNVFAIVEKFTHRTMHPMEIQYWAGVIMRNACRKDDSRKGIRQCAYTGCGKWETKPREFAKCRRCRKAKYCSKQCQSKAWNEGHRWWCIEKKPESMGVSTSFGTDLPPAPPPPPPPPADLQDQPEATPNIMENGGISMATGAGARMIGGGQGGNSTGHHVHRVQQPNQHQHQDQGHLYYQLGHRPLSSTPNPQAQLSAQAAASSLPSTQVVPQDSQQHLLQRQQLILPQQPQTSQIPYHATQQQQQQQQLRQQSVSEHSTQDRQVLQQIQMQQQQHRHLQAMQQQQRLPQMRPAPIPSSSPRPMVPTPQRSMSQSHPSTAPIRASSRTELTPHLGISPDSPTPEQLAQRFVQQAALYPGQHNELAQSLHAQFQQFFPPHHQAEAKRQFSFHARELFARHQRQQELLRNGGLGSSLNPNGRSTPYSAPITTSGSGSSSLSRSNSHMETSKQGTPRRRSDLDSDEEYPSNTHSNSHMTSTSFSVPMLTQDLSTTMSLSSMELSGPPPTSIMDGRLSTEPNSIPCATDEAKADQTSVRDFKVRKLMSREESSNHEGGSSSGIANREPVQRGDGWSYSRHMAKDASVDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MKB2</accession>
    <name>A0A9P6MKB2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005532</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002723">
        <property type="protein sequence ID" value="KAG0004960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MKB2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0004960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="169" mass="18848" checksum="E78AE5903136AA47" modified="2023-09-13" version="1" fragment="single">MPRVKKSTLHLRKIARRRKLLTPEPFTPTLNQGLQDENVTYVQPVREGNEIQELSRDMEEWGAILAEPDSDGPVDDDTDEKDWQEARRTLESGEDWSGLLQKMQLAAAAVKPTKPRDGTTRQNLHRRKTILKRAAAGTPPLSTFGFTVSAPRSSTIQEADSISAAPFGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MKD9</accession>
    <name>A0A9P6MKD9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_005270</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002605">
        <property type="protein sequence ID" value="KAG0006486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MKD9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0006486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="191" mass="21757" checksum="CE68BAC48C6F3C38" modified="2023-09-13" version="1">MCSVFSQKYQEEAIAALRKKELKRSEPADVMVPAGVFEPFNVTPLMTRVFGAARLKEIRKSFEVELEVDAPEHHDSAVLKSIRLKLNGKGDEALDALCVMENRDYRNLFEQFILKLPKLEDPPSAEETLVTNFVSPILRAFLQRTDDDIITHFPNTDSDTRKKQGIDPDRPDFKVSINKREVAFGEVTGYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMA8</accession>
    <name>A0A9P6MMA8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_004613</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002335">
        <property type="protein sequence ID" value="KAG0007480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMA8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0007480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="146" mass="16446" checksum="18449B28881ACE11" modified="2023-09-13" version="1">MGDLFDATPKDLISKVFIEEKMFKTCCDSRSVLIGDAWHKSMKDSGLSSINWAFGEYYKQRYGRNVAVFNGSATFAKFLNGQKIMERLFRTVVLKVLTHLTLKSGIRKDLAYQLQIAYLPLIENRGNGPVLPQEFGESTLMNVAGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MME5</accession>
    <name>A0A9P6MME5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">SUMO-conjugating enzyme UBC9</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Ubiquitin carrier protein 9</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Ubiquitin-conjugating enzyme E2-18 kDa</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">UBC9</name>
        <name evidence="14" type="ORF">BGZ80_004300</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein sumoylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002202">
        <property type="protein sequence ID" value="KAG0007742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MME5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019787">
        <property type="term" value="F:ubiquitin-like protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016925">
        <property type="term" value="P:protein sumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd23798">
        <property type="entry name" value="UBCc_UBE2I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000035">
        <property type="entry name" value="SUMO-conjugating enzyme ubc9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 12" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="13">
        <location>
            <begin position="4"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="11">
        <location>
            <position position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00039165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00081544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0007742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="157" mass="17875" checksum="273948726C0FAE45" modified="2023-09-13" version="1">MSGICRSRLAEERKQWRKDHPYGFYAKPDKKPDGTLDLMNWQVGIPGKANTPWEGGVYKLTLAFPEDYPSKPPKCKFVPPLFHPNVYPSGTVCLSILNEEEGWKPAITIKQILLGIQDLLNDPNPESPAQSEAYVMFKKDKVSYEKRVRQQAKENAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMF0</accession>
    <name>A0A9P6MMF0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004144</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002143">
        <property type="protein sequence ID" value="KAG0007863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMF0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="351"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0007863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="407" mass="46302" checksum="ACFB8443C51287D1" modified="2023-09-13" version="1" fragment="single">MDFKVKVEDLSKGISKLKSRTWIKNTIYLSGPSWPRAQRVWLSSRGQGSGLSFIHVGTSEKSQVPARRRGLIVEEESESDAEDLGNPWTPPAYTGHELDINPPVFGASGPKMTCLYTQIDFDEDESQREIEQELDLELRRDLEEGAESSIHKYEQESLMDGLTEGPSRKRKREVRSSYSQITEELVKRLIDHWVINMCSVTEAAHAVYMNPRTAWRNTGEFPTKKRRVVPKMSKQHCEFIEKYLDDKPLSTLREFHMHLHNKFPEFRVSLSRGHYNSTEMCKYNGTILLSLQQERRLLRKCKSWGSWRITERKPANVLRPTARGRNISALGAISSSGIIGMSVLVVEPNQAPAAETRGGDESSEAVGDGEAVVEVPRGRGRAVVVIMEEMWDNHKWRKTGLLLAQPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMQ7</accession>
    <name>A0A9P6MMQ7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">cyclin-dependent kinase</fullName>
            <ecNumber evidence="2">2.7.11.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BGZ80_004355</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.22" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010002229">
        <property type="protein sequence ID" value="KAG0007687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMQ7"/>
    <dbReference type="OrthoDB" id="1732493at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007346">
        <property type="term" value="P:regulation of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07843">
        <property type="entry name" value="STKc_CDC2L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000054">
        <property type="entry name" value="Cyclin-dependent kinase 11B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000211">
        <property type="entry name" value="Cyclin-dependent kinase G-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045267">
        <property type="entry name" value="CDK11/PITSLRE_STKc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF107">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 11A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="132"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="415"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="23"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="59"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0007687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="479" mass="53964" checksum="136B6F8FC954AADD" modified="2023-09-13" version="1">MEQGAAASKWAREPSSDEEETQRRKKREKRFKKSKDSPSFREGSGTPNSTSGRLVRGGDSQRDSALRYEATLRPESGEPMEITDDHDAPSPSTSTPRGSVIEPAIQPEEYRITIPDSPQHPVLAGCRSVENYEKLNRISEGTYGVVYRAKDRVTGEIVALKKLKLDQEKNGFPITSLREVYTLLLAKHPHIVNVREIVVGDKLTQIFIVMDFIEHDLKELMSGMRAPFLQSEVKTLMLQLLSATELLHENWILHRDLKTSNLLLNNKGEIKVADFGLARRYGEPQGMMTQPVVTLWYRAPELLLGSKQYTTAIDMWSIGCIFAEFVNNEPLLPGRSEAEQLEKIFKLLGMPNDKIWPGYSKLPLASHVPNFVQPYNLLRSRLPYLTENGLDLMSRMLTYDPVKRITAEEALQHPYFSEAPPPKHPSMFPTWPSKGERTAKRNASPSAPQAGHGHGQDDDEAGGLFNFANQESTGFRLKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMS9</accession>
    <name>A0A9P6MMS9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_003946</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002079">
        <property type="protein sequence ID" value="KAG0008020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMS9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0008020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="440" mass="48774" checksum="BD6ACBDE017C824F" modified="2023-09-13" version="1">MGRSTSEGWFSIDLDESYIVTQEQIPNTSSESTSDPQQNQLHGTITLRLSKPTKIKSLSLTFTGYARTSFCFDSSSIPGAMPCASHVISTKSININYQVTASLQTPSILPFGSTHTISKPVILLQKDELPSDDLFDTTVMRVSSEDTDRVSCKVSIPCAVFPEAGTIPLTLNLSLKGNATTVSRITIEMMESVYTRLSPKTNQEERNETLIDERVVTRQNCPVHDWPSSTTEEPVMIPRRLLFKVPQLALSAWSKSKHLTLSCQRSSLDRGFCHSSGTFAHADIRIAHTIRVTVYVRGLSEDGGSSVAYDYGENETTVWIVGNQEYKDDEVHPPSYYRSFSTKLVEEDKIQEIDQRAFEALQDDLPCSAPPPYCEESFVGTSASSSPTLTSLTDHGRISLDQFSLNESLAESTNDNDTYARDLATYTERYSYSSPAVLAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNA2</accession>
    <name>A0A9P6MNA2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_003601</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001963">
        <property type="protein sequence ID" value="KAG0008306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNA2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040387993" evidence="3">
        <location>
            <begin position="40"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="274"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="425"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="157"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="193"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="248"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="433"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="506"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0008306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="515" mass="54392" checksum="3AB41B372C9E0498" modified="2023-09-13" version="1">MTSISKTHLTQVFTHNTHINSLVLILSCLSCIIIPAVHADLTCQSPIGSYKPGDTVTLLWSDNGQYPQVEDVYSTAATVYCSSNKAALLQLGSVTDAQTWTIPDNIITSCPSSPIYVEYSGQMYDVLHLLHIATYTLNCRDIFLPSSSETSSPIDPIPSTQSTNPSSTSITPIVTTGTATVPASPGSAQQPLPGSGTSSGSDPGSESGSEPESGSGSEPGSGSGSEPGSGPGSGSGSGSGSGSGSGSGSTATPTSSTPNQPGSNTIINDSGLNIPAIVLGTLAAAILITFIIYSMIKARKRRMEKRLMAREKLDEVEIAGATESAGTVGQGRSGRRRRGESVVSLEFVPLQHRSDMQDYVRYSSSQFSAITDIQLLQDSGYRGDIGCNNRLSISRSQPHTLGNIDEHDLEQSFPFPEREELVFATSQPTSQEYRSRLRQSDGSHEISRHPIYPTPTVNPAHPTHLNSVPTDSGAMAENSDPPLEMIPIHPGSVPGNQSHEQNTPEDDPKSGLHEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPC9</accession>
    <name>A0A9P6MPC9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_003320</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001870">
        <property type="protein sequence ID" value="KAG0008551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPC9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0008551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="266" mass="29770" checksum="F1AC70C81F33894C" modified="2023-09-13" version="1">MDAIQDLYKNYHSTESTWIQSLSQASQYGAASSPSIQDCSLHYGELGFLLAGLKPCVLIQLPSPDLTHSLYQHVLVSKWMQLASYKEQQQSQSLGLNCHLITKDVRSPEMSLQGCILVWSDRTVQSHPQSLRIRRGISLLCSSQTQKDPPAAGTNNETAVKDINTQSISEQDLAVMLDLPGRLPESEKEMHQMIEVSYWHQGDVDVANGQNDKATAEESPTLLTAFAAQPDQVSSIQIHFKRYRDTVREIFGMQLKLHIQSMADLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPE7</accession>
    <name>A0A9P6MPE7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_003005</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001770">
        <property type="protein sequence ID" value="KAG0008837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPE7"/>
    <dbReference type="OrthoDB" id="2384430at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="150"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="165"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="190"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0008837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="666" mass="73866" checksum="BCCADBEAE2F1FC65" modified="2023-09-13" version="1">MSEERQEEILQEFRAVYKDKTSGTTTLFTETVKIKPWLITKSGEHIILWSDVVTAFGNPVHVWSGDMVLPFLTDENSGVLQPLRISAHPGLVLDVTIETPGIEAAMESLRIQGSPASSSTLSTLPGIHFSQELFSAASNASPPTITEITAQTQQSRRARKDCSESQEYTPSDPESNALPHQSVPNFEDDGPCHHDETQPIIEHQRHSSGSACRYSEGNAYEDYIQGLAYYEGKDVCQDYDKALDLILRAANRGHAPAQLRLRDIIESQQTVEHDYSKAYEWYQEAASQGCADAQSNLGFLYEVGYGVTKDDYKAVEWYQKATEQGHAYAHCNLGFMYDRGFGVTQDYFKAVELYRESADAGCARAQSNLGFMYEDGSGVTQDYSKAMEMYRKAADQGYTIAQCNLGLMYEDGLGVTQDYSKAVEWYLKAANLGYSDAQYNLGLMYAAGNGVTQDYYQAVEWYQKAVNQGDADAQCNLGIMYESGYGVVRDYSKALELYQKSADQGNAIGQYNLALMYECGVGVTQDYSKAVEWYQKSAIQGRCAPSYRLGVMYRDGGGVPQDYSKAEEWFQMAADQGDAESQYILGVMYQNGHAAIQDYSKAIELYQKAAEQDHTIAQYVLGLIYENGSGTSKDISKAIEWLSKAANNGHGGANELLGKYQGSNQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPJ4</accession>
    <name>A0A9P6MPJ4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">HRK1_2</name>
        <name evidence="12" type="ORF">BGZ80_003388</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JAAAID010001893">
        <property type="protein sequence ID" value="KAG0008484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPJ4"/>
    <dbReference type="OrthoDB" id="6513151at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13994">
        <property type="entry name" value="STKc_HAL4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24343">
        <property type="entry name" value="SERINE/THREONINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24343:SF137">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE HRK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 12" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="402"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="27"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="63"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="152"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="263"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="351"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="692"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="74"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="286"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="319"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="351"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="706"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="431"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0008484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="743" mass="82877" checksum="211777DCC81653DC" modified="2023-09-13" version="1">MVVADNLNQIKPSTLEKKTIAISTLARSTRSLEEEGNSDMPTVAITPADLQNQSRLIAAPHYSEEPLEDDDNADVSSLDQTSDYDLHSEDSHSIFPRRQSSAGSFSAVRPLQGCYPRISATASPSSSLMVGPHLTRTNTESTDVLVSMPASMEASRANSDDEDDSHHHHHHHHHHYHRHSPAPHHYHPHHDPSSILEWTQRRQLNGQHFQLQQPFIQPEAQVENSAQQEDTDIKDLTEALEDQQLECSSSTKVDSCHVCNAGDSTPEVESEDVSSEPMPIPTPRVPKATAAEVSSAASNSSALSPSFSESPSRRASFFSRKKVKLSRKKSARETSHGIFHDLKRFLKVRSTSPTLSPSQPNGHVESKSHKTKKSGKSSSEKAHHHHGPHGNCIETDLRKKYGKIGKVIGSGAGGTVRVICRDSDKKSFAIKQFRKRKPNESERTYIKKLTSEYCLGSTFHHPNIIETLDIVHEADNYYEIMEFAKHELFTAVMSGAMGRDEIACCFRGVSNGVAYLHEMGVAHRDLKLDNIVMNEQGIVKIIDFGCSMVYQHPFESKIHMAKGISGSDPYIAPEVFTTEEHDPRLADVWSLGIIFVCMTLRRFPWKLAKRDDTSFESYCNSSGAGKNRLLKLMPRESRPILARMLEVDPAKRALMTEVMEDSWVKNIEACTIENSCLYHSHHLGEDPHMIWNPHPKPRFDGRTAPADDDDDEDEDEKIENKAAPSAIPTSLAANLQVPVTPVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPK1</accession>
    <name>A0A9P6MPK1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003360</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001885">
        <property type="protein sequence ID" value="KAG0008504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPK1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318:SF247">
        <property type="entry name" value="GH16156P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="221"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="455"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="75"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="221"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="265"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="458"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0008504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="663" mass="72916" checksum="F55BC72BB0EF1D2B" modified="2023-09-13" version="1">MADDNKKVQDPPNTSQNQQTSHNVIPQLWHSPYMAYYVSWMKFLKTISTTGNNNNKKSSKNTTLKKLKKKKKSTSDSSSSSQSRDVGSISSPSSQQNSGGNPNDTVVQDPYGRFEGSHARLIMSGGSTVRGFPSNSRIIEKESNGRGNKDQRQGDDGDVDNDEDEDEDEDDDDDGDMSGLLRLAESQRQNQVQVGWGGNCTSEREVSTHGFTFHAREIFSPTLSSSSSSSSSPTPPPRSNKSSCVDVDDSDDASGKTDKHGLNIKASNNNHTSSICRNEGDGNMITGATAAAATVSTTPSPQHQHQQTMLITPPTTTTPPTITLTTSFTLRPFEYGSLIRVLDFSHLYYIISDKFLTHLLPQTPLLLELVIHSPKQFSDESLICLSKSCSLLRRLELQGCVKISDLGLGFVLDACLNISTLVISHNGAADITDRTLSQLAMATFPLFTKHQYQHQHQHQQQSSQTRGDQGQMPQDLLQQQQRHSSRAQRLRVLGLSCPSYFITEGNPGLMSIAIWCTNLVSLDISNLTPLVTDELLRLVSKTSPEAEIMTGAGIEAAAAAPSSYPSCLKRLNIAHCSLVTNKGLFYLARGCPDLRQLDITGLHLVDDQGILEIAKRCRSFKKLIMDDKFGARIAREILKNFPSWGAEVLRQGMTFERRGSRTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPU0</accession>
    <name>A0A9P6MPU0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003166</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001820">
        <property type="protein sequence ID" value="KAG0008693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPU0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0008693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="104" mass="11516" checksum="EA6816AE3485AA62" modified="2023-09-13" version="1">MSTVQNAEQGIFTLRALLQHIQNNMEAVHQLLAMQAALQEQSQQSNATPQDQANITNALQALIAQNLEFAQMQQNASANTQRSVAQSPRNQIPLPLTTKFKPSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQ48</accession>
    <name>A0A9P6MQ48_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DNA repair protein rad52</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RAD52</name>
        <name evidence="6" type="ORF">BGZ80_002923</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RAD52 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001749">
        <property type="protein sequence ID" value="KAG0008905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQ48"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045002">
        <property type="term" value="P:double-strand break repair via single-strand annealing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006312">
        <property type="term" value="P:mitotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.390.80:FF:000001">
        <property type="entry name" value="DNA repair protein RAD52 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.80">
        <property type="entry name" value="DNA repair protein Rad52/59/22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041247">
        <property type="entry name" value="Rad52_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007232">
        <property type="entry name" value="Rad52_Rad59_Rad22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042525">
        <property type="entry name" value="Rad52_Rad59_Rad22_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12132">
        <property type="entry name" value="DNA REPAIR AND RECOMBINATION PROTEIN RAD52, RAD59"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12132:SF1">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD52 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04098">
        <property type="entry name" value="Rad52_Rad22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="219"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="330"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="10"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="230"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="330"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="340"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="354"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="393"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="422"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0008905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="548" mass="60142" checksum="92F715BE94F5EDE5" modified="2023-09-13" version="1">MIPKTEPGMSRSSPLPTGNSTPEILNDIPTVITHVPQNSCHSHQTTRLVEFTPEEKARLNVDLPKYLAPEFAATRAGPGRTTLTYIEGWRIKNLANKLFGFNGWSSSITDVTVDFLDLDHEGKVSVGVSVMVKVTLKDGTFHEDIGYGSSENQKSKAASFEKAKKEATTDGLKRALTSFGNVLGTCLYDKNFCKYLSMQKVDKPKFDSKEIYYYPTEAQPTPQDQERKQQQQQQQQQQQRQHQNNQQHQQHQNHCQHNNQHNNQHNHQHNQNQQQISHGAGPSSAAVSEVIPNPYQATKSRLTTPTLLQVASNFSGRPASVATSIVTRVNANNQAQNETRNGEQRNTKVEDDVQTTPTKIAPSLTPQGQGLKQEQTQAQKPVPFRMAVPPNDSFSSSSSALSSNPFAPKETLPSPSLSIQNTTSTKLSTPSTPHAQDGSHSSRQVNNIKHHQNQNLRNGKEIVSPFAARNSNGPQSVAVNGTRNVLRANSMAAAAQNHASTSLPPTNQNSTVHGHKPGTYSSSTAQHSVHLLNPVQGTGLKRPLGMTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQT4</accession>
    <name>A0A9P6MQT4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Serine aminopeptidase S33 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_002005</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001481">
        <property type="protein sequence ID" value="KAG0009845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQT4"/>
    <dbReference type="OrthoDB" id="10249433at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051044">
        <property type="entry name" value="MAG_DAG_Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11614">
        <property type="entry name" value="PHOSPHOLIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine aminopeptidase S33" evidence="1">
        <location>
            <begin position="32"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0009845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="299" mass="32986" checksum="A5A993CB971ACB52" modified="2023-09-13" version="1">MSTTENPRSKEEWIVADDGHEIYTKTWFPEGKPVASVVFVHGFGEHIVRYDHVFEEFNKAGIQVSSFDQRGFGKTGKKSKSLGLTGGYAKAIPDITAALQRGEIEGVPLFLMGHSYGGGQVLNYDCIGPLRSRLAGVISSAPCILLCPPHKPFDLTVSFAGAVSKALPSLQIPVSVPAKILSRDPEEVRKYDADPLVHGYGTTKGLFDMLTQGKALLTTRYKEISPDVPLLIVHGSGDKLTDSKASTEFFNKVQVKDKELKIYEGYYHELHNESVADRKVVIDYYIQWIQKHLPSTSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MR30</accession>
    <name>A0A9P6MR30_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Purine-cytosine permease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_001368</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the purine-cytosine permease (2.A.39) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001307">
        <property type="protein sequence ID" value="KAG0010579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MR30"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015851">
        <property type="term" value="P:nucleobase transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.4160.10:FF:000002">
        <property type="entry name" value="Purine-cytosine permease fcyB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4160.10">
        <property type="entry name" value="Hydantoin permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001248">
        <property type="entry name" value="Pur-cyt_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026030">
        <property type="entry name" value="Pur-cyt_permease_Fcy2/21/22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31806">
        <property type="entry name" value="PURINE-CYTOSINE PERMEASE FCY2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31806:SF1">
        <property type="entry name" value="PURINE-CYTOSINE PERMEASE FCY2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02133">
        <property type="entry name" value="Transp_cyt_pur"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002744">
        <property type="entry name" value="Pur-cyt_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="66"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="96"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="132"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="171"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="201"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="233"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="268"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="327"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="365"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="396"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="437"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="476"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR002744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0010579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="514" mass="56025" checksum="DD447803796B6584" modified="2023-09-13" version="1">MTSLEKSASPEVLDGKIPVENTMNEVETSGRAQTWFRKVFLGVELRGIERVMPEDRQSKGVINNLLMWWSVNCVLTTIPIGTLGPAIFGMGLRDTILSIIGFTILGCFTTAFCATLGPKLGLRQMVISRFSFGWWGAVVLSLLNIITQIGFSVIAVILGGQTLVYVCGSNLPLSVAIIIVSVMTLLICFFGYDLVHKWERYAWILISIIMCILYGTGHKYYSWTPSTSSGADLAGSVLSFGGVVFGSVIGWAPIAADYNVMLPEDTNAWKVFGLTFLGLFIPLVFVETLGALYGAALINNPAWNAIYEDGNAGLGSVLGESLSSLGGFGKFLVFILALSVVSNNVPNTYSAALSIQTLGKPFQRIPRFIWTVLVAVIYTVAGVAGKSRLSEILNNFLSILSYWTTPFVIVLALEHFVFRRRNGYNVDDYNDRSKLPLGLAGGLAFIIGVVGAVLGMNQTWYVGPVGKLTGTYGGDLGFEMAIGFTTVSFLVLRHFELKYSGREQLREYPSPNYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRA8</accession>
    <name>A0A9P6MRA8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_001268</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001287">
        <property type="protein sequence ID" value="KAG0010675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRA8"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24296">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="455"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0010675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="519" mass="58615" checksum="A029BC1CC2A65370" modified="2023-09-13" version="1">MATSAIINELVKHSTKPNSLKLLAAVCAFILFKYRAHAVGTRARRDLKQPKGAVPLLGHMPLLLTIPGTKLYDFFLKNNQELGPVWSISLPFIGRMIQGDTPEMVEHVLKTNFWNYEKGPTFKGALGDLFGDGIFVADGHEWKLQRKLASHIFNVKAFREYTSDVFVIEGQRVVDYLTKAADEGTIVDLHDLFLRFTLDSFGTISFGQSFGCLDSINEKVDFAISFDDLTATCSDRLLDPAWKIRERLTSVGKKAAYDKDLIGKHARSLIEKRRREGAKSAKKKDLLQLFMDTKDEDGKPLSDDFIADIILNFTIAGRDTTAQALSWMFYLLGRREADPQLTKDLVNEVEEVLHGEMPTYETYKQLKFAEACFHESLRLYPSVPRNMKQCVKDDILPDGTKIHKGEWFTWSSYVMGRSELIWGPDAKEYKPSRWINTEKPSQGKFNSFHVGPRVCLGQQFATIEAITMIAMILSKLEIELVEPDKVPAYGVSVTMPMLHGLPVRIHRRNTGTASLAKAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRN5</accession>
    <name>A0A9P6MRN5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_000834</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001183">
        <property type="protein sequence ID" value="KAG0011236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRN5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051104">
        <property type="entry name" value="FAD_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46720:SF3">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46720">
        <property type="entry name" value="HYDROXYLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G01460)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="13"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0011236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="181" mass="20313" checksum="422A0E7DC58C3A05" modified="2023-09-13" version="1" fragment="single">MSQDTSEARSRPEVLIIGAGIAGLTLAILLEQINVPYHIFERAPEVKALGAAMSFHGGLFPALEQLGIYEELKQIAKVYTHVDFYNAHIKKMGSFSAEENRNASGYETLIFSRPRFYEILLKRVPEQKISFKKKVLRTEEKEGKVHIHCSDNTSYAGDILVGADGAYSGVRQSMYKLMNEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MS15</accession>
    <name>A0A9P6MS15_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Amino acid permease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_001301</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001295">
        <property type="protein sequence ID" value="KAG0010634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MS15"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649">
        <property type="entry name" value="AMINO-ACID PERMEASE BAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649:SF26">
        <property type="entry name" value="OS04G0435100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="36"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="121"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="171"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="223"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="248"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="284"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="319"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0010634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="384" mass="42045" checksum="9F526F3D4159EF1A" modified="2023-09-13" version="1">MTSGYVASTYVIFGIYVGIIILHGMVNSLTVRLNGIFNVISVWWHVFGSALIVIVLLATTSKKQSASFVFTQWENNTGWNSDFYVFMLGLLQSQYTLSGYDSAAHMSEETKNAQKGGPWGIIRAIVTATVVGWLFLVGVTFCITNFDTQIVNPTVGVALSQMFLDSAGETWAIILILVVLGAQFFCGSALTLASSRMVFAFARDGALPLSKHLHRLNKDKSPVAAVWFNIAFCFILGLPYIWSETAFSAIVSVNTIASSISYLIPILCRIVLARDSFEPGPFHLGRFSIPIGIVATAWIIITSILFLCPISYPVTAENMNYASVPFVVVIGLCVIYYAIWGRHWFKPGGTRILEPNMTEVEGSLELSGEDEKAELSEEDIVAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSS7</accession>
    <name>A0A9P6MSS7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Zinc finger CHCC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_000671</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001143">
        <property type="protein sequence ID" value="KAG0011466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSS7"/>
    <dbReference type="OrthoDB" id="307899at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006120">
        <property type="term" value="P:mitochondrial electron transport, NADH to ubiquinone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.260.40:FF:000003">
        <property type="entry name" value="NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.260.40">
        <property type="entry name" value="q5lls5 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019401">
        <property type="entry name" value="Znf_CHCC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13156:SF0">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 6, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13156">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 13 KD-A SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10276">
        <property type="entry name" value="zf-CHCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zinc finger CHCC-type" evidence="1">
        <location>
            <begin position="95"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0011466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="138" mass="15178" checksum="7BBD689104A1AF59" modified="2023-09-13" version="1">MNAVKCIKVPATSTIAAARNLIATRALSSSVVVANNIRNDLKQSVNRDTTWSENQLEKKLAFRGPRFENTDIDAQPKPRAAIELIAEEPIRMVEGRRAKCDGGDGSLGHPAVWINLDRPGAHACGYCGIRFEQKPHHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MST0</accession>
    <name>A0A9P6MST0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">histidine--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_000867</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>tRNA(His) + L-histidine + ATP = L-histidyl-tRNA(His) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17313"/>
            <dbReference type="Rhea" id="RHEA-COMP:9665"/>
            <dbReference type="Rhea" id="RHEA-COMP:9689"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78527"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.21"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.21" evidence="1"/>
    <dbReference type="EMBL" id="JAAAID010001190">
        <property type="protein sequence ID" value="KAG0011194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MST0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004821">
        <property type="term" value="F:histidine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006427">
        <property type="term" value="P:histidyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00773">
        <property type="entry name" value="HisRS-like_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041715">
        <property type="entry name" value="HisRS-like_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004516">
        <property type="entry name" value="HisRS/HisZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43707:SF1">
        <property type="entry name" value="HISTIDINE--TRNA LIGASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43707">
        <property type="entry name" value="HISTIDYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13393">
        <property type="entry name" value="tRNA-synt_His"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="4">
        <location>
            <begin position="43"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00047639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0011194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="173" mass="19876" checksum="D1C48AE5A7A46CE2" modified="2023-09-13" version="1" fragment="single">MYQQGACADASAPKQTHAVQGMKDRFGDENRRFQWITEKGARLASLYGFEQISTPILEYAQVFERTLGEDSDVVGKELYSFESRRGQHRLTMRPEGTAGITRALISQKQYIELPKKYYYYGPMFRHERPQKGRLRQFEQFGVEFYGESHPSSDVETIELASKFLNGLGLESVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTB9</accession>
    <name>A0A9P6MTB9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA ligase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_011554</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000943">
        <property type="protein sequence ID" value="KAG0012728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTB9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021122">
        <property type="entry name" value="RNA_ligase_dom_REL/Rnl2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09414">
        <property type="entry name" value="RNA_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56091">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNA ligase" evidence="1">
        <location>
            <begin position="45"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0012728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="186" mass="21274" checksum="2218D01BD2AFCC01" modified="2023-09-13" version="1" fragment="single">MFRGLILDKRVYPPKVVCLPLLAIDTVEKGLVSSFKFLSHEKQIFEASVKMDGTSMVMTSYQGRMIVATKNRFKSTRVDFVKAILYARNITESAFRENYTYICEYVGGPNCRVIEYPYEEMCLLTVIDNLTGVELDYERRRSIADALGFITPATVYFTLTRSFDDVMHCFSEIYGSIEGIVVRTSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTQ7</accession>
    <name>A0A9P6MTQ7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transcription factor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_011225</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000878">
        <property type="protein sequence ID" value="KAG0013206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTQ7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="422"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="460"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="460"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="485"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="537"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="581"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="596"/>
            <end position="608"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0013206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="730" mass="82184" checksum="6F6DD6B88AB60F07" modified="2023-09-13" version="1">MRRLISLYMRYVHPLQRIVDENDSEFLTKLDHPIKPEIASVVYAMCAVGAILKSKAPGSGHLDDLVYYFHKQALTAIEERPKDLITLQTLLIIQNVHVVAHRTKESSEAYLQMKEIATSINLGERVLKSASQDTLSQEELIMRNVWRMLIWWETMANMTSLNNGSIDPLKDLSSKAIDSRPDEIPSPYFYFTSLFKIFQEITKIRLPMSPRDLHPVTGILDQFQTWHNSLPKNLRCNPRTGGTGTSPSHATSLDLYFRLGHILLLNVLPLSARSSPTGLGPRRESPLRILATCANGITAAMGDLVKEPDLRSYCMVHGMRCLTEAATIQLFNSKESDPAISTPAKVNFMKTLWCIKQFNFAVPTEILSTVLARYDTALKQTTSGQRPADKGSQGRRELSLASDCSSSTCSTREGSHITICETDDTDRERPFLSPSSPPQDGAASSLLALSLESPTAIQRGSIESSSIHKISQDVQGLASPRETSRVGQQATEFKPSLQSSGMDTFERDEQRPSSASFLSPKLEPSAQPKLVPGYDSQYDSRYTSVSSYSDHSWKSRRTGSGEHYQNEHDPGLAYAHTSRTVNEDRPPDGEHDIIFRQPPRQRSASQSSFTQNEFGMPRSLQIRESRRMSPDYSHQEPHQSRRVLKDSLGGLDLNLYILIWIFRVILTTPLVKRVHVHHILQIQKWACVMDMEVLIWRIKNCDIKELGGTYVWDMIHVPDMAMFTIINVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTW9</accession>
    <name>A0A9P6MTW9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_010987</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000828">
        <property type="protein sequence ID" value="KAG0013577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTW9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050722">
        <property type="entry name" value="Pyruvate:ferred/Flavod_OxRd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002880">
        <property type="entry name" value="Pyrv_Fd/Flavodoxin_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32154">
        <property type="entry name" value="PYRUVATE-FLAVODOXIN OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32154:SF0">
        <property type="entry name" value="PYRUVATE-FLAVODOXIN OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01855">
        <property type="entry name" value="POR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyruvate flavodoxin/ferredoxin oxidoreductase pyrimidine binding" evidence="3">
        <location>
            <begin position="229"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="134"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="145"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0013577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="447" mass="47723" checksum="902001D139FA75A0" modified="2023-09-13" version="1" fragment="single">MLTVLHTLANTAGLFSKNSASASLVATPANPSQKINQALQNLHLVRKIILVQNLDEAQEQAALTRLDQLLDQISVNALASLNYDQLQDLATALTNTATTNSKKLTQILSQIRSSTTATTTTTIKRTIITSTSGTRTVTRGDDDNASVTSEGPSSAVTVVDDHDQLSLSVCSNLSLKIQGDADLFQLTSGNLVVEHVAYSLRDLVFVYPSISSNTYLGYASEQWSKAGLSNAIGRALAPQVLKMSTRSNAASAVLGAVTSPESKRNALSTLESLAVIVNMVPNLYQIAQSTTPVVFHVAAESVDSDLNVHRGDYSDVLVARETGLLYLASNSVQEAYDVSILAHAVASGTNQSVIHVLDGVQTSQQVESIKTVKDQDVAQLIKQEHNKSIQGHDEDSLVSGIEGIFERAATLLGRNYKAFEYNGPKDAETVVVVFGPAHNVAHNLGEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MU63</accession>
    <name>A0A9P6MU63_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ARM repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_011228</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000879">
        <property type="protein sequence ID" value="KAG0013197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019888">
        <property type="term" value="F:protein phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051023">
        <property type="entry name" value="PP2A_Regulatory_Subunit_A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10648">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A 65 KDA REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10648:SF1">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="HEAT" evidence="2">
        <location>
            <begin position="117"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="602"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="772"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="849"/>
            <end position="1192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1266"/>
            <end position="1289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="611"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="625"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="784"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="858"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="895"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="934"/>
            <end position="945"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="946"/>
            <end position="960"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="966"/>
            <end position="995"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="996"/>
            <end position="1016"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1038"/>
            <end position="1057"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1082"/>
            <end position="1094"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1101"/>
            <end position="1139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1145"/>
            <end position="1154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1268"/>
            <end position="1281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0013197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1362" mass="149470" checksum="DD3AA0940666082E" modified="2023-09-13" version="1">MLDLGLYFGDEEDEEQLAQEDKALSYLVLSNEQDDAFDPVETEDLLAQLSTDSLISHTVGLDEDTDVVRLLAEPNLSAVEKVQLLAQSDHDFHRSLAAREMPMLMQQMRTQQAISHLIPLIRHLSLDPTDSVRESLASQIDKIALYFYCNSIIDNNSRKPLALDDFSEDYEDNELPEDDDLKSDPPPPLPHDILTSVFLNLLLDQNAGIAHQARLAIDTVTQNIPDDVLESEILNGVIAGLEKLYIPEGSGDYEQEDYDRFNKCGQDLHLSNKDDQDGEAELGKMLVVVEIVMALGALCKVVDQDIVVNKLLPMYDIFVQDDTWHIRRACCTILASFVGSLPVDMKATKVEEIYNIFSVDVSRSVRNSIMEVLGEVIAGFERNMVPDSLLEHFLNMGKQPMNEHERAVMCAFSFPAVVLTAGPSKWELMKPVYMRLAGTFRSPIRRSLACSLHEIARILGPELADRDLAVAFADCLSAEDEVKEGILGHVVEFISCLSPECRSGALNDLRRAWADLERSSNWRLRDSLVGQLSALCEIADGDDLLQVLLPLSVKACTDGVSTIRESAVMAFPALWDASERVGAVKKPRARVCSTSGLDFMPLCESEDDTEGDKPLRDSRALFDQSDAEDTEMEEITESTTDSEEQSSLERSSETEDSPRPQPLTQPTTTIKEQVISQVADFAINGGFRSRVVAVQIIQSLLDHGIPTHEFEEHFLSVLVDHLANDAVANVRIWVARVVSWIIESEYYGDVVDSPRLSEALTKLQQDPDRDVRIYSGGPAELPKKTKKTKKAKAKKAKKNGVLAKKEGENTSMIKLTTTTISIFRQNPKSGEPAVMGEEQVNIEVDQITVDGERREIHIEEEDDDDDDDDDDDDDEDDDDDDDDDDDSDDGDDEEGKGGKDVDVASEDHAIHDAFSQPRESAEPDNDSGIFVPGEAEEEEVIDPSEDSTPSTNIKSPTSLADATVESIHDNQIKYDIEDKMDQDVQKEEEVEAKVEEEVEEEEEEEEEEEEEEEEEGIAERVIPYTTLTSSGASPLDVEMNDSSEEEESVEMKDEEEGIAEHVVPYTALTSNGASPLDVEMENSSKEESVETKDSSEEEESVEMKDSSKEEESVETKGSSKEEESVESEPAKSESAKSESSESESAGKTDQTQGSGEEPNVTLHTELDGPSATAFPPLCPSSPSPTILRHPSTPKLLSYAASVKNGDDFKTKMQLSNPHTMTSFMQANIPEPPIPSAATRKAAVADAQIRKAVNVKLSAAFGTQVSAINSNNKGNNKSNTNGKSREPLFAESSFPSISASSTLSLSNMTSPSSSRVPSSASLPSSRLPFSYASVVASGAAAAARAFPPPLPSPISAASTAVTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVK7</accession>
    <name>A0A9P6MVK7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_010501</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000738">
        <property type="protein sequence ID" value="KAG0014327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVK7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050562">
        <property type="entry name" value="FAD_mOase_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356:SF2">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356">
        <property type="entry name" value="FAD-DEPENDENT MONOOXYGENASE ASQG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="189"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0014327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="353" mass="40175" checksum="A98B236CFD788C1F" modified="2023-09-13" version="1">MFSRPDLHKLLLSKIPPNKIHFNKRVLSVGQSDKGVLLRCADGSIYEGDILIGADGAYSAVRQSMYERLQKENLLPRCDTISLSAGYACMVGTTVPQDPEKYPILKDDYSHLFVVVAEGKPHSWTVITVPGNRFCFGVVIQLGDKERDETFRNSEWGPELIDSMIAQVADHKVPCGTLGDLIQATPKELISKVYLEEKLFETWNHDRIALIGDACHKMLPSAGQGAINAMQDAVILANCIYELRSRSHKQIVAALKDYKSQRYDHAKKQVQISSTVGKVFYGQTWHEKLMRRAVFTWMPMSFEERSFFKLVGYRPQVTFQPFVENKTNLKILPQKMSKRYAEEQKLNQENQKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MW16</accession>
    <name>A0A9P6MW16_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">DNA polymerase</fullName>
            <ecNumber evidence="12">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">POL1</name>
        <name evidence="18" type="ORF">BGZ80_010331</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the DNA polymerase type-B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="12"/>
    <dbReference type="EMBL" id="JAAAID010000707">
        <property type="protein sequence ID" value="KAG0014633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6755010at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005658">
        <property type="term" value="C:alpha DNA polymerase:primase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006273">
        <property type="term" value="P:lagging strand elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006272">
        <property type="term" value="P:leading strand elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902975">
        <property type="term" value="P:mitotic DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05776">
        <property type="entry name" value="DNA_polB_alpha_exo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05532">
        <property type="entry name" value="POLBc_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.132.60:FF:000004">
        <property type="entry name" value="DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.2820:FF:000001">
        <property type="entry name" value="DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.10.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3200.20">
        <property type="entry name" value="DNA Polymerase alpha, zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.60">
        <property type="entry name" value="DNA polymerase family B, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.690">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1600.10">
        <property type="entry name" value="Palm domain of DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006172">
        <property type="entry name" value="DNA-dir_DNA_pol_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017964">
        <property type="entry name" value="DNA-dir_DNA_pol_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006133">
        <property type="entry name" value="DNA-dir_DNA_pol_B_exonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006134">
        <property type="entry name" value="DNA-dir_DNA_pol_B_multi_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024647">
        <property type="entry name" value="DNA_pol_a_cat_su_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042087">
        <property type="entry name" value="DNA_pol_B_thumb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023211">
        <property type="entry name" value="DNA_pol_palm_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038256">
        <property type="entry name" value="Pol_alpha_znc_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045846">
        <property type="entry name" value="POLBc_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015088">
        <property type="entry name" value="Znf_DNA-dir_DNA_pol_B_alpha"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00592">
        <property type="entry name" value="pol2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45861">
        <property type="entry name" value="DNA POLYMERASE ALPHA CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45861:SF1">
        <property type="entry name" value="DNA POLYMERASE ALPHA CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12254">
        <property type="entry name" value="DNA_pol_alpha_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00136">
        <property type="entry name" value="DNA_pol_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03104">
        <property type="entry name" value="DNA_pol_B_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08996">
        <property type="entry name" value="zf-DNA_Pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00106">
        <property type="entry name" value="DNAPOLB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00486">
        <property type="entry name" value="POLBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00116">
        <property type="entry name" value="DNA_POLYMERASE_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12" id="KW-0235">DNA replication</keyword>
    <keyword evidence="10 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9 12 18" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 12" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DNA polymerase alpha catalytic subunit N-terminal" evidence="17">
        <location>
            <begin position="22"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed DNA polymerase family B exonuclease" evidence="15">
        <location>
            <begin position="474"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed DNA polymerase family B multifunctional" evidence="14">
        <location>
            <begin position="783"/>
            <end position="1233"/>
        </location>
    </feature>
    <feature type="domain" description="Zinc finger DNA-directed DNA polymerase family B alpha" evidence="16">
        <location>
            <begin position="1271"/>
            <end position="1450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="54"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="97"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="107"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF03104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF08996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF12254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAG0014633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1458" mass="165066" checksum="744426B362311821" modified="2023-09-13" version="1">MSSRTKRKATERGSAIAKFKAAKAAKESGISRIHQYEVEEAEDIYEEINDDNLHKRLQEDHDDFVEDDDGRGYAYEDEDERERYSDEFSDGETPNRGSKKNGKSKHTTKEVPKPSAKENIKDAFMRAEVRTKVTRPATSKPVTENSDYLDSLFGLLDEPASKINTTPTKKPMFTKKVTVETPTRALLKLKIKDEEHDEIPRNLSSQLGSHNHDNDAFGDGFDDGFDDYGIVEETPQPELELRTEIKKEIKQEPDINPFVVDDDYSPLEVKNIALRDSKVPMKLFNDTSKKEKATVIKKSENENRLDWMSVESNLNQSYTETKVEDGGAIDIQEVNIKEEDGTLKMYWIDACEVRGVVYIFGKVLRKSTNTGSDTYISCCVAVHNLERNLFILPRARRVDKHGNEGEEVGMADVYTEFDSIRQSHKIPSFLSKPVERKYAFDLPGIPSSGEYLKVVYKYSSPSLPADLKGETFSHVFGANTSALEHFIIKRNLMGPSWLEIKNAKLNNTKVSWCKSEFTVSDPKDIKPLKDSPDLPPPPLSVMSLSLRTVLNPKDKSNEIVAVSSSVYHEVRLDDTVENNKKFISKEIYIRKLDASPFPPGFDRLIEKNRVISKQPSERALLNRVLARFRSADPDIIVGHNFVGFDLDVLLHRMKHTKAEHWSSLGRLRRSVWPKLQSGAGGMGDTTAQEKSIMAGRLMCDTYLGAKEHVRVKSYSLTNLAAEFLNAHREDIDYEKIPLYFSLAKDLETMLLHTDYDTYLCAELMFKLQLLPLSRQLTLLSGNLWSMTLTAGRAVRNEYLLLHEFHKSKYICPDKSYYSDNKEAVGVINVDDMEDQDEAAAPKKGTRRKPQYSGGLVLEPKKGFYDRYVLLLDFNSLYPSIIQEYNICFTTVKQDKGKDDDTLPDYPEEGLPQGILPRLLANLVERRREVKKLMKTATGAKYDEYDIRQKGLKLTANSMYGCLGAAYSRFHAKPLAMLITSRGREILQNTVDLATESGLDVIYGDTDSIMINTNTTKFEEVKPIAEGLKKIVNARYKLLEIEMDGIYQRMLLLKKKKYAALTVVEKNGKLETATETKGLDMVRRDWCGLSRDVSEYVLTQILSSDNQDREQVVETIHSYLRTVGEETRNGLIPIEKFIVNKGLTKAPEDYADAKSQPHVQVALRRKSKGISARTGDTIPYVICIDENSPTQKGSFAERAYHPDEVVNGSGLKIDVEYYLNQQVHPPLDRLCGPIEGTDATRLAECLGLDTSKFRSVLRSSGGQDEELQTLASQLSDAERYKDAEALELRCRSCQSTYTCSALLMETNGASRFGLQCPTCEAIPQAASASVLLTLAIRKYIQKYYQGWVVCDDQGCRNRTRMVSVLGRRCLVEGCRGVMHNEYSDGSLYTQLSFFSHIFDAHKALDKVDFDKNGAIRVQIQHNRELIGQLKACADKYMENNARRFVDLSQLFSFVKIASH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWB0</accession>
    <name>A0A9P6MWB0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_010028</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000656">
        <property type="protein sequence ID" value="KAG0015139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWB0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="177"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0015139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="272" mass="29116" checksum="94D864E163AB697B" modified="2023-09-13" version="1">MVGPSMRPPRSISGSSSAAAAAAVAMAMATVANARFLNAGFSQSSDGTIDLARSSSSPRPVHGSERARLAARMEEYHQLGTLPLSRRSSASARVVDDGSGSSDLPRHRRKLQSYSSSPSSLRNLFIAGGTSLRSPSLTLSPINKYIPSNAQGGRESQPEAKGVYDYFNLPLSYSRESTPTASSPSCPSLSRAPAQFHPLDESKTSLSSTSSLPPTPTRVIFESPYDSLASPTPIQAHIDKVDTPFSQYRGEQQAPRISSRNMRLLALNRITY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWC8</accession>
    <name>A0A9P6MWC8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_009961</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000645">
        <property type="protein sequence ID" value="KAG0015247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWC8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050562">
        <property type="entry name" value="FAD_mOase_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356:SF2">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356">
        <property type="entry name" value="FAD-DEPENDENT MONOOXYGENASE ASQG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="20"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="309"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0015247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="472" mass="52588" checksum="EBFBEA0D88BC9158" modified="2023-09-13" version="1">MATIYPSQPPPICLDGKTPHVMIVGAGLAGLLLAILLDRINVPYEIYERSDKVRPLGGAMSLNANILPALEQLGLFEDLKKVAYPSLTFNIYSGNMEKIEKIATLGGDDKAFEAIGYENHLFSRPKFYALLLSRVPPERIHYKKKVMSIAHNREGAMIRCSDGTTYHGDILVGADGAHSGVRQSLYKLMQNDGLLPEPDTKALSKGYICTVGTAGPMDPEKYPCVNDPTASSYQIIGEGTPYSWSFMSVPNNLVCWNIVKQLGSCESEDERFRNSEWGPESNEAMIKEVRDFRVPIGTLGDLIDATPKDGISRVFLEDKLFETWNHGRTVLIGDACHKLLPSSGQGAVNAMQDAVILANCIYELRSVAENDVAEALRDFKEQRYPHVKDQYRASQMSAKLLYGQTFFEKILRKVVLNYMPKSIQRKSMTKDLAYRPQASFLPQAPKRGTLNVISQKPSKRYQEKQELAAVSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWH9</accession>
    <name>A0A9P6MWH9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">N-alpha-acetyltransferase 16, NatA auxiliary subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">NAA16_1</name>
        <name evidence="4" type="ORF">BGZ80_009812</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000620">
        <property type="protein sequence ID" value="KAG0015521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWH9"/>
    <dbReference type="OrthoDB" id="10263032at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031415">
        <property type="term" value="C:NatA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.1040:FF:000003">
        <property type="entry name" value="N-terminal acetyltransferase A, auxiliary subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.1010:FF:000002">
        <property type="entry name" value="N-terminal acetyltransferase catalytic subunit (NAT1)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.1010">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.1040">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021183">
        <property type="entry name" value="NatA_aux_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22767:SF2">
        <property type="entry name" value="N(ALPHA)-ACETYLTRANSFERASE 15_16, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22767">
        <property type="entry name" value="N-TERMINAL ACETYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12569">
        <property type="entry name" value="NatA_aux_su"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000422">
        <property type="entry name" value="N-terminal-AcTrfase-A_aux_su"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="579"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="599"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="631"/>
            <end position="641"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0015521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="839" mass="96433" checksum="ACD80CF081CEA684" modified="2023-09-13" version="1">MSELPPKEANLFREILKCYEMKLYKLGFKGAEQILKKFPEHGETLAMKGLFYNHMDKKEEAYEFVKKGLRYNLRSHICWHVFGLLHRSDKNYEEASKCYINALKYDKENIQILRDLSLLQMQMRSLEGYIDTRHQLLELRPQNRQYWVAVAIGYQLTGKPELGIKVLTAYEETLKDIPSTPDYEHSEMLLYHNSLLEEAGDIQAALDHLSTIEKHVCDRKSLKEKRAKYLLALGRLGEAEAAYRALLSINPDNMAYFEGLRTSVGLGGEKLSAEEQVKVLELLKGLQKEYPRSNAAKRLPLRYATGEAFVKIADEYICSMLRKGVPSLFVNIKTLYTDKEKEQAVEKLALGYLAALDKSKGFDHSGPHIEPPTALLWTLYFLAQHFDFKRNTDQALGYINRAIEHTPTLVELYMTKGRILKHAGDYIAAMEALNEARELDLQDRFINTKCTKYMLRADKTVEAEKTVVLFTRADIANPLNDLVEMQAQWFSIAAGESELRQKHIGRALKRFHQVHKYFVDYTEDQFDFHTYCLRKMTLRAYVSLVRLEDQLRSHPFYVRAAHKAIECYINLFDHPEGADTEEMEGMTEAEKKKYRNKQRKAELKAQQEAEDLKKKSIANGDASKKAGGAGKVDEDPEGTKYSKVEDPLAEALKFLKPLQDLASERIETHLYGFNIYIRQKKLLLALRSLLKANKIEPNNATLHEQLVRFALEVQKSSPKPGVKAVIDQHWSTLYQGQDLVAFTAAFLEKNKDFGSVNHVISAAQASYLISSSDNKNSKSESLSKGEKLLFSIQDDQYQKTRSVENAILVQTLLKKWRSSRVQEWNEKAKTWYPRATAFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXS5</accession>
    <name>A0A9P6MXS5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Vacuolar import and degradation protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008145</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GID4/VID24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000433">
        <property type="protein sequence ID" value="KAG0017581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXS5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034657">
        <property type="term" value="C:GID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045721">
        <property type="term" value="P:negative regulation of gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007039">
        <property type="term" value="P:protein catabolic process in the vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018618">
        <property type="entry name" value="GID4/10-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14534:SF3">
        <property type="entry name" value="GID COMPLEX SUBUNIT 4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14534">
        <property type="entry name" value="VACUOLAR IMPORT AND DEGRADATION PROTEIN 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09783">
        <property type="entry name" value="Vac_ImportDeg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00061469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0017581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="276" mass="31653" checksum="65E7E8328149C27E" modified="2023-09-13" version="1">MPVFARISTADPVEAASIIATTLDGDSDMLQDVVCICPTSNSPTPIDGVLSDCAHVAPVHFQGHLSSCPFHLDSALTFSQMKQSALLKQQQRLQQQKDTARRRDPFEYVRLMPTRTCHLYPGSKFQGRQESGPHSYDVMVDIKDVNLHESTLCGYLHIKGLTEQYPELTTFFDAEIIGPEYSFLTKKWDASEVTDEEHWTQFEPFEGVANMYKLEDAKYDYRNKDYVFMRWKEHFLVPDHRVEGIIGASFAGFYYICYNKQTGQISGYYYHHTSDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MY64</accession>
    <name>A0A9P6MY64_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Rho-GAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_008625</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000473">
        <property type="protein sequence ID" value="KAG0017085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MY64"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060237">
        <property type="term" value="P:regulation of fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051025">
        <property type="entry name" value="RhoGAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15228:SF25">
        <property type="entry name" value="F-BAR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15228">
        <property type="entry name" value="SPERMATHECAL PHYSIOLOGY VARIANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rho-GAP" evidence="3">
        <location>
            <begin position="38"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="246"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="314"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="323"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="366"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0017085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="400" mass="44749" checksum="0E336A017B560C5B" modified="2023-09-13" version="1">MAQQKVSFKKWWKNITGTKAVKGLFNIELMDSIAYAGLPVHYTVNGKTRCQGYIPTVVSKCGWLLKEQAMRTRGIFRVSGSAKRVAELQLIFDTPPHYGSQLDWTGYTIHDASNVLRRYLNHLPDPVITLEYYEKFRDVHRNLTDDDEKIAAYQDLISKLPPPHSCLLMYLLDLLSLFAHHSDENLMDSKNLASVFQPGVLSHPDHSMSPGEYMTSAAVLKFLIDHQSSFTMPKPNIDDDDEEMVNLEPVSHPPQHQLPTQGDPDLHGGGYVTASDHERIHSMALDGVSFEANDAVHILDTGVRRQLSLQKPIIPHSTLPGNSPQRSKSNSSISSRRSSGLLSPTLLSKRRSNRSSKVGSKIIAESESSPSQDEVDATQNYESHGRSIRILPTGNFIKRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MY83</accession>
    <name>A0A9P6MY83_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">DNA replication licensing factor MCM7</fullName>
            <ecNumber evidence="12">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12 14" type="primary">MCM7</name>
        <name evidence="14" type="ORF">BGZ80_008673</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:13066"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the MCM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="12"/>
    <dbReference type="EMBL" id="JAAAID010000479">
        <property type="protein sequence ID" value="KAG0017025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MY83"/>
    <dbReference type="OrthoDB" id="3207464at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031261">
        <property type="term" value="C:DNA replication preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042555">
        <property type="term" value="C:MCM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005656">
        <property type="term" value="C:nuclear pre-replicative complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043596">
        <property type="term" value="C:nuclear replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017116">
        <property type="term" value="F:single-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006271">
        <property type="term" value="P:DNA strand elongation involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006279">
        <property type="term" value="P:premeiotic DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd17758">
        <property type="entry name" value="MCM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.28.10:FF:000004">
        <property type="entry name" value="DNA replication licensing factor MCM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000288">
        <property type="entry name" value="DNA replication licensing factor MCM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1640.10">
        <property type="entry name" value="mini-chromosome maintenance (MCM) complex, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008050">
        <property type="entry name" value="MCM7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027925">
        <property type="entry name" value="MCM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF26">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14551">
        <property type="entry name" value="MCM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24901">
        <property type="entry name" value="WHD_MCM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01663">
        <property type="entry name" value="MCMPROTEIN7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 12" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 12" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="13">
        <location>
            <begin position="352"/>
            <end position="558"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU365012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0017025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="759" mass="85516" checksum="5223E8911954CA41" modified="2023-09-13" version="1">MNRANVRVKYSDETEHIKDFLQTYKSVLTEADVEDTGMEVEGAPQLKYFKQLQLIANRRQKKLVIHLDDVIKYDRTRTSNLGHNIASNTKRYVSLFCNAIDAIMPAPTEDMDHTTSVLDVILSQRRSHNNNYIAANGDVPLNELPFPPALTRRYQVVFKPATNQKALSVREIKAEYLGKLVTLQGIVTRVTAVKPFVEVAAYTCESCGNENFQEVTARQFMPLTECNSQVCKTNQTKGKLHEQTRANKFLEFQEVKIQELTHQVPVGHIPRSIKVHLYGVMTRTMNPGDTVAVSGIYVPIPYTGFQAMRAGLLTDTYLECHHVEQSKKQYSEMTISSDVQEELEEMAQDPDVYQKLARSIAPEIYGHEDVKKALLLLMVGAPTKTMGDGMKIRGDINICLMGDPGVAKSQLLKYITKVAPRGVYTTGKGSSGVGLTAAVMRDPVTDEMILEGGALVLADNGICCIDEFDKMDESDRTAIHEVMEQQTISISKAGITTTLNARASILAAANPIYGRYNPRKSPVENINLPAALLSRFDILFLILDTANEENDSRLASHITYVHMHNQAPRMDFEAYSSSLMRHYIAAARQKRPVVPKAVSEHIVDAYVQSRQNGKAERENGQEFTYVSARTLLGVLRLAQAMARIRLSDTVTVEDVNEALRLVDVSKASLYDQDPAHNGQDGRSYSSPTDRIYDIIRTMSKDPEDNWRLVEELRLQEVRDRVLAKGFKMQEFEDCLREYEEMNIWFVNDAQTKLTWISRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MY88</accession>
    <name>A0A9P6MY88_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">5'-deoxynucleotidase</fullName>
            <ecNumber evidence="7">3.1.3.89</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">HDDC2</name>
        <name evidence="11" type="ORF">BGZ80_007605</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the dephosphorylation of the nucleoside 5'-monophosphates deoxyadenosine monophosphate (dAMP), deoxycytidine monophosphate (dCMP), deoxyguanosine monophosphate (dGMP) and deoxythymidine monophosphate (dTMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxyribonucleoside 5'-phosphate + H2O = a 2'-deoxyribonucleoside + phosphate</text>
            <dbReference type="Rhea" id="RHEA:36167"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:18274"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:65317"/>
            <dbReference type="EC" id="3.1.3.89"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the HDDC2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.89" evidence="7"/>
    <dbReference type="EMBL" id="JAAAID010000392">
        <property type="protein sequence ID" value="KAG0018065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MY88"/>
    <dbReference type="OrthoDB" id="10254258at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002953">
        <property type="term" value="F:5'-deoxynucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3210.10:FF:000016">
        <property type="entry name" value="HD domain-containing protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3210.10">
        <property type="entry name" value="Hypothetical protein af1432"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039356">
        <property type="entry name" value="YfbR/HDDC2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11845">
        <property type="entry name" value="5'-DEOXYNUCLEOTIDASE HDDC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11845:SF13">
        <property type="entry name" value="5'-DEOXYNUCLEOTIDASE HDDC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13023">
        <property type="entry name" value="HD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD/PDEase" evidence="10">
        <location>
            <begin position="148"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00009999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0018065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="307" mass="34447" checksum="8FEE49882E2D8873" modified="2023-09-13" version="1">MDSFPATDIGGSLLEPYTAVVNLQYKGAVYDTSIRILPQTDTKGLYLAAKVMANIPESTPVSLIRLDHRGEYVTNPRVLNDGELLEILEGSVEESNVVARIAELQSKAGKSASSNTTHSVRGTLQFLHTVEKLKRTKRTGWLNHQIKPAESIADHMYRMSIMALLIDEKTAGVDKNRCIKMAIVHDLAESLVGDITPYDGVTVEDKHTREKNAMHHLCHELLGWTEQAQEIEELWHEYEAAATPEALLVKDFDKFEMIVQALEYEKSENTTLESFFAGTRGKFKHPMVTAWVNELEAERAESRAIKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYA5</accession>
    <name>A0A9P6MYA5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_007234</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000367">
        <property type="protein sequence ID" value="KAG0018379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYA5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="239"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="620"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="694"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="419"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="102"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="259"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="626"/>
            <end position="645"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0018379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="816" mass="92992" checksum="A34ADB1AA2071295" modified="2023-09-13" version="1">MPKSQHRIGNPRARVRKSLPVPSSKFFERPTSIATAAAAADQANGHLTNDAAHNLSTVQRSGISRTRRRTNSTSSTSTTYLRKAAAAVIASVHQTHLRMQQQQQKQLQQQKQQQQFGTAQALSSESFDELRALYDEREEGYTSSTDIGPEYRHSHHYYQYSQPCEPGEDDAVVLQSYLRHSQTQSEHYQGNFSSYNDFYQGASRAVSAQVVPENDLNIYDQQHSDDNWATASYPSAYLRSEAQVDPTNSHQRRRRSKIQQLPKLQLHPQPHQQLESLPATANKDIPFGAAIDSYLIPESNTKHDILAARFNRAQIDHYPVIESEEVMATGHQHTPNGDARMLDGQYCDDHNGHEGLEGRYHDRDYNPSQGIHNDLISPIQSSFLVSQGNNNKNNNAWDLEMHSETEQQPWLGYIEEQMYSNTDILRQQQEEARDRLQEQHLLDTISQLEQEVVELRDANRELQAFLRESEERYDCLATEFDARICQIQDEHELSKEETKRRAKRFHDEAMKKREKEEEKRLTSMQEHVGQLEASNKELCATIRAMQRERFETERSQRDDLAALSSFLQNDIIPTLHNMLVMPVEMERAQADDAKPLPVPLALQTDTLWDKVHGRKFMDKLVESPDTISPPASKSSTTTSDMDSPDPLVGRPPSKEEHSSSRSCTTLRGQKCLKLLEHLWTILITVSPTAAVGHREYPTASRGDIGDEDQTLWRKQQKRHSDSSISSGKTLVIPRLILPSNSSHFIATATTTEHSDTLTAFAFDGHKEAQEPLDREAGMDVKQQCIRLYRESLEDVRTEMLAKVTQKCAKNHIKKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYG8</accession>
    <name>A0A9P6MYG8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_007810</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000407">
        <property type="protein sequence ID" value="KAG0017883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYG8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0017883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="291" mass="32875" checksum="309C45C796EA2FC1" modified="2023-09-13" version="1">MAIFHIKWSAKCYTFGGCSTFRSGTIDDFEPFLNVPDTWYFVDSSLDPILNRAKTIIAASPKTLYSEVNQYREVDKAVPWRYFVVSWIPEELKECRTSVEGFGVVPDEAIEDFYSKVGGELKQHGNLKIAKTTALERLKLALGRVNEPVVLMQLFSPGKDTLDFSSSVSYRAEFWFDNSFRDHSMYRLDWASTYVASHVAALPSESVCTHILTRLTKDPIGSASGIMLEVYVLHAFGEGGHIFEIKYLESGQLSQLEIPRNPETMDFSTITQTTEGHYAYQGAATLPVWIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYH0</accession>
    <name>A0A9P6MYH0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">poly(ADP-ribose) glycohydrolase</fullName>
            <ecNumber evidence="2">3.2.1.143</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_006949</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the poly(ADP-ribose) glycohydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.143" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010000348">
        <property type="protein sequence ID" value="KAG0018619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYH0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004649">
        <property type="term" value="F:poly(ADP-ribose) glycohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990966">
        <property type="term" value="P:ATP generation from poly-ADP-D-ribose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009225">
        <property type="term" value="P:nucleotide-sugar metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006282">
        <property type="term" value="P:regulation of DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046372">
        <property type="entry name" value="PARG_cat_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048362">
        <property type="entry name" value="PARG_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007724">
        <property type="entry name" value="Poly_GlycHdrlase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12837">
        <property type="entry name" value="POLY ADP-RIBOSE GLYCOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12837:SF0">
        <property type="entry name" value="POLY(ADP-RIBOSE) GLYCOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05028">
        <property type="entry name" value="PARG_cat_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20811">
        <property type="entry name" value="PARG_cat_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PARG helical" evidence="8">
        <location>
            <begin position="187"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="PARG helical" evidence="8">
        <location>
            <begin position="403"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="domain" description="PARG catalytic Macro" evidence="7">
        <location>
            <begin position="477"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="133"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="249"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="380"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="141"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="165"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="253"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="280"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="299"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="311"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="500"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="518"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="519"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="503"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="517"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="558"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR607724-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR607724-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0018619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="765" mass="85603" checksum="8085C3721DAF66F9" modified="2023-09-13" version="1">MTSNASATTRANDYFETGPNHVLCQVPGLDQDPFPAEFQHTWDLEHVRLPCADRTYPTEVNYWPEIVSGLTEPILTSVQLSEVMLRWCPGKRNGWNINALDAFLNNRSAEDDERIQQGTHSDVVLDPVEQKAQGELDSDDYGTNSDYDDGSSLQKQQEVVEPAEGQGGIAASGSGVAGGPLKSQFLSTQERQHFFDVTLPRMQVLALRLPELVKKPIPFLKMQKDSAVTLSQEQIACLLANAFFNTFPCRNTPYKRGRKKKPAFQRGNSGSNVSQGQQQQDDDDGSDDSEEEDRKHQPKNNNAKSNKGGASSRGGRGGRGGGGQAQQQSRGGGQAQQQGRGRRSIYAPRPPRKRRAQGPAAQFEFFDDVDQDLSASVAKLDVEDQEENPEASSSGAFKKEDEWVPKMPSINFISMFWSEENKTPCTPTQAAKLRCILHYFDRVTTEMPQGTVTYHRQVLKKPAYLNPGEMLREGEFYLSKVTVDSFTPIEEAPQGALQLDFANKNIGGGTLDKGAVQEEIRFMICPELIISRLFCQQLEANEAILIKGAERYSNYIGYSKTFEWFSDHQDPTPRDKLGRRVTEICAIDARPFKSRVSRLEQFERHYVLREINKALAGYRVSPINASEWGLARKDGKNGESSLAANNGNRPIATGNWGCGAFGGHLQLKFVLQWLAASMCAGFSHERVGDRLGDDLLYYTFGMHELRGEIETFVKGVEAIGKPVDPKRVMESIIHYPRRNSAGEIQKFRERTLFEYLIEQPYRMCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYI3</accession>
    <name>A0A9P6MYI3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Arf GTPase arl1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">ARL1_1</name>
        <name evidence="14" type="ORF">BGZ80_006953</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the small GTPase superfamily. Arf family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000348">
        <property type="protein sequence ID" value="KAG0018623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYI3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04151">
        <property type="entry name" value="Arl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000510">
        <property type="entry name" value="ADP-ribosylation factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024156">
        <property type="entry name" value="Small_GTPase_ARF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11711">
        <property type="entry name" value="ADP RIBOSYLATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00328">
        <property type="entry name" value="SAR1GTPBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 11 13" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="10" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0519">Myristate</keyword>
    <keyword evidence="5 11 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="24"/>
            <end position="31"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="126"/>
            <end position="129"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0018623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="179" mass="20053" checksum="682CBEED373CC420" modified="2023-09-13" version="1">MGSIFSRILGRLWGDKEVRILILGLDGAGKTTILYRLQVGEVVTTIPTIGFNVETVQYKNIKFQVWDLGGQTSIRPYWRCYYANTDAVIYVVDSVDRDRVSTAKEELMAMLEEEELKDASLLVFANKQDMAGAMTAAEVSDALGLSTLMNRQWSIYKTSAVKGEGLTEGLDWLINIMQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYN7</accession>
    <name>A0A9P6MYN7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BGZ80_007938</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000417">
        <property type="protein sequence ID" value="KAG0017770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYN7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005337">
        <property type="term" value="F:nucleoside transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008276">
        <property type="entry name" value="C_nuclsd_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011657">
        <property type="entry name" value="CNT_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002668">
        <property type="entry name" value="CNT_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011642">
        <property type="entry name" value="Gate_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10590">
        <property type="entry name" value="SODIUM/NUCLEOSIDE COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10590:SF4">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 28 MEMBER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07670">
        <property type="entry name" value="Gate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07662">
        <property type="entry name" value="Nucleos_tra2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01773">
        <property type="entry name" value="Nucleos_tra2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="71"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="118"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="173"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="204"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="357"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="383"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="490"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="domain" description="Concentrative nucleoside transporter N-terminal" evidence="9">
        <location>
            <begin position="123"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleoside transporter/FeoB GTPase Gate" evidence="11">
        <location>
            <begin position="205"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="Concentrative nucleoside transporter C-terminal" evidence="10">
        <location>
            <begin position="304"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0017770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="516" mass="56085" checksum="9A9DE49FCC856844" modified="2023-09-13" version="1">MSEKMENEKDIGLHRRHTSEEMADEEAHIEEEDNKKVLGIQKRKFITIIQVLFWMFFTAFLVVAATLKKNGPISIIAVSYAFYTLYLISDHTREGTFANPANAVWNADNESGTRVQRVISLCGLTFFVLAFYITSRNRKVIHWPTVALGIGLQFLLGLFVIRTYIGQTIFSYIGGFMATFLGFSSSGIGFIVGDDFMKLYGNSFLIGVLPAIIFFGGVIQVLYYYNVIQTTISAMGRVIEISGIEVISACAAPFVGMSESAMLIGPYLENATNAEIHQVMTSGFATISGSVYLGLVSFGASPTHLITCCIMSVPCAFVTSKMRYPEEEVPLSRGKAIKLERPDAEDSFIHALSNGSILGMQLAIVVAAVLIGFLSLIGTANYFLNWFFLFFGASGVSIQLILGYFFYPFAWFVGIPTADLMASSQMMGIKYGVNEFVAFADSQSNNFFTTASPRAVLLATFACCSFANPSSLGSQISLLGKMAPGRASDIARVSVSAIISGALSTIMSACIAGIVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYS5</accession>
    <name>A0A9P6MYS5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 11">Chitin synthase</fullName>
            <ecNumber evidence="2 11">2.4.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">CHS1_5</name>
        <name evidence="14" type="ORF">BGZ80_008084</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10 11">Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>[(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n) + UDP-N-acetyl-alpha-D-glucosamine = [(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n+1) + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16637"/>
            <dbReference type="Rhea" id="RHEA-COMP:9593"/>
            <dbReference type="Rhea" id="RHEA-COMP:9595"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17029"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="EC" id="2.4.1.16"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Cell membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the chitin synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.16" evidence="2 11"/>
    <dbReference type="EMBL" id="JAAAID010000429">
        <property type="protein sequence ID" value="KAG0017624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYS5"/>
    <dbReference type="OrthoDB" id="26569at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030428">
        <property type="term" value="C:cell septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004100">
        <property type="term" value="F:chitin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006031">
        <property type="term" value="P:chitin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04190">
        <property type="entry name" value="Chitin_synth_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004835">
        <property type="entry name" value="Chitin_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013616">
        <property type="entry name" value="Chitin_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914:SF9">
        <property type="entry name" value="CHITIN SYNTHASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01644">
        <property type="entry name" value="Chitin_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08407">
        <property type="entry name" value="Chitin_synth_1N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03142">
        <property type="entry name" value="Chitin_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="4 11" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="473"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="516"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="547"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="603"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="732"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="763"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin synthase N-terminal" evidence="13">
        <location>
            <begin position="56"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU366040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0017624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="794" mass="89558" checksum="1564A1BC844FABF8" modified="2023-09-13" version="1">MPTHTPTPDGSYPFAGGYGSQSALVPPSPYPYYQPQQNGTTLHYGPAPPRQTRRYKTTKKVTLTQGNLVLDCPVPSKLLDVLPRKNGEEFTSMRYTAVTCDPNDFAQQNYTLRPKMLNRETELFIVMTMYNEDEILFCRTMHGVMKNISHLCARDRSKTWGAQGWKKVVVCIVADGRYKCSRRVLSVLAMMGVYQEGIAKNAVGGKEVVAHLYEYTAQISIDPDLKVKSADHRIPPVQILFCLKEKNKKKLNSHRWFFNAFGPILNPKVCVLLDVGTRPGSTSIYHLWKAFDVNKHVAGACGEICAMTGRGCVNLFNPLVAAQNFEYKMSNILDKPMESIFGYISVLPGAFSAYRYSALQNDAKGNGPLASYFKGENQSGDIDNIFSANMYLAEDRILCFELVAKRGGQWKLKYVRSAIGETDVPDSVPEFISQRRRWLNGSFFAAIYALTHSTNIWRSDHSIVRKLWLHLEFFYNFVSIIFSWFALGNMYLTFYFLTRSLADPTIDPFGHGWGAIIYEVMRYLYIFLICAQFICSMGNRPQGSKATYTMSMIAFALIMGYMLFAAALITIKSLQAVFDDVNGSQDSLLVVETLVKSATFRNIILSLISTYGLYILMSLLYMDPWHMITSFVQYLFMMPSYINILNVYAFCNTHDVSWGTKGDNTTHSDLGEAKKSDGQVVEVEIPTTAADINEAYDDAIAELSHKVQEVHQSRSAATKQDDYYRGFRTRMVMAWIGSNGLLVAVICSTAVEQKLTLDDGSNAYLAAIMWSVFGLSLFRFFGSIIYLFFSLFSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYX8</accession>
    <name>A0A9P6MYX8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BGZ80_007654</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000396">
        <property type="protein sequence ID" value="KAG0018010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18579">
        <property type="entry name" value="ABC_6TM_ABCC_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18580">
        <property type="entry name" value="ABC_6TM_ABCC_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000013">
        <property type="entry name" value="ABC transporter C family member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000997">
        <property type="entry name" value="Multidrug resistance-associated protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000074">
        <property type="entry name" value="Multidrug resistance-associated protein 5 isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044746">
        <property type="entry name" value="ABCC_6TM_D1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044726">
        <property type="entry name" value="ABCC_6TM_D2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056227">
        <property type="entry name" value="TMD0_ABC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF399">
        <property type="entry name" value="ABC TRANSPORTER ATNG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24357">
        <property type="entry name" value="TMD0_ABC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="126"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="157"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="288"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="341"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="417"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="445"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="522"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="577"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1026"/>
            <end position="1049"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1091"/>
            <end position="1115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1160"/>
            <end position="1180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1186"/>
            <end position="1208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1274"/>
            <end position="1293"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="14">
        <location>
            <begin position="304"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="13">
        <location>
            <begin position="698"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="14">
        <location>
            <begin position="1079"/>
            <end position="1329"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="13">
        <location>
            <begin position="1366"/>
            <end position="1601"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="663"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="934"/>
            <end position="990"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="672"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="696"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="934"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="950"/>
            <end position="962"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0018010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="17">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1606" mass="177587" checksum="F16D85AE9F0C3B23" modified="2023-09-13" version="1">MPFCDAEGWTVFSESRPMDFTLCFQDSVLTLIPSVILLIFITPRINKVIGKGRLEGVKASPLFHLKMLLVLAAVGIQVAFLAELVSESNYLSSALLSTVLYLVGLIAAAALHYFEYFNIANPSAGLLIFWLFTALISIFPTRSWIEITPNGLSSPLPLLKLLFTIVSFLIFILENIPKPKRESLKRHDALPIDQKNPSPEPRSNYFVRVTFFWLVPLLEKGKKKALKMDDLFDLNPKLLSYPLYLTTKAKMDADEAIKLQAIKDEETKGINEEDSKIKRGGINLFGTLAYTAGYSFLAAIFPRILYIAAYYVRPILFSDLISFISTYSSTSLSQGIAPEPAWVGFGLLIAVFASGTLATIFNNQYVFICYNASIKTRGVLINLIYRKSLRLSSTDKQEGMGSIVNHMSTDVDNIMQFFNIAHYSWSSIVELIITAIMLYNEVRYAMFASIGAAFVIVLCAGLASPQIAKANKAMMARSDHRLKLVTELVTYIKSVKLYAWEKYFAGKINKAREDQIVELRRFYSWLTVLVSFGNSIIPFCIFSTLAAYSGIATEDEPLDTRRIFVTITLINMLQEPIGYVMGSANTIFTGIVSYGRLRDFLNSEEINSENVLRNPDAASSDVAYEVTDGTFGWYSPSAIKALAEKKEKEAAAKAEAEAKEKALAEKKKKSGKKTDEETESGEKGDKAELDEEDEKDTTKVLDEKKDDSESVPDGSRDNTGPVLHNISFSIKRGSLSLVVGRVGEGKSSLVGALLGEMHKYSGTVRSFGSLAYVSQSAWILNDTVRNNILFGRPYDKQRYLETIRACALTPDFKMLVSGDKTVIGEKGINLSGGQKQRISIARAVYANADVYIFDDPLSAVDAHVDEHIFKNVFKSILASKTRILITNGVNHLKDADQIILIKQGRISQDGHYEELIQNEGGDLFRLVQESKLVASKEEDEKEGDEKESITEGEDDLEEGEESNTEHSGDEDAVDTTAEKPDMVKRPSFKRNKSSGVKEDFVELDEKDEVDEEVIAKGNVGWPVYKYYLSSIGLFSISMLVLASACMVGIQVGTQLWQGHWGKSNDITAAESAIAGAPVQPEHSTGYWVATYFAWSISFTLVLALLSGVSLIYLSLRASKTLHSAMVSPLMRSPMSFFDVTSSGKIVNRFSHDITAVDTQLPVTFIHGLVTMFSAATIFGMCIAASPYFAIIMLPLSVAYYYLGGYFLVSNRELKRLDSAARSPLYAHFSETLAGLTVIRAFGDSSRFAVDAMGLLDRSQQTSYLINVSTRWLQIVLDFLSVIVLTSVGLLAILTRHSANQQVFSIVLSNIGSLTLMMSDVLTCACTLETLIVSVERIREYINLQPEARDYIPDSKTDEAWPQRGQITFSQYSTRYREGLDLVLKDINVTINGGERVGIVGRTGAGKSSVTLALFRIVEAAKGSITIDGIDISTLGLHELRSHLTIIPQDPFLFGDSIRVNLDPFNKHTDAEIWAALESASLKSYVQTLPEGISSTIDNGGENMSLGQRQLMSLARAMLAQNTRVLCLDEATAAIDVETDNAIQRALRREFAGCTVLTIAHRINTIMDSDRILVLEKGEVAEYDSPENLLQKKDSIFFSLANKSGNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-06-18" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N242</accession>
    <name>A0A9P6N242_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">ER transporter 6TM N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_000436</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000109">
        <property type="protein sequence ID" value="KAG0022359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015743">
        <property type="term" value="P:malate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020966">
        <property type="entry name" value="ALMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018823">
        <property type="entry name" value="ArAE_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018820">
        <property type="entry name" value="BRE4-related_DUF2421"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023244">
        <property type="entry name" value="Brefeldin_A-sensitivity_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052430">
        <property type="entry name" value="IVT-Associated"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47804">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47804:SF3">
        <property type="entry name" value="PROTEIN BRE4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11744">
        <property type="entry name" value="ALMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10337">
        <property type="entry name" value="ArAE_2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10334">
        <property type="entry name" value="BRE4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02047">
        <property type="entry name" value="BREFELDNASP4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="293"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="341"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="377"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="400"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="431"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="1633"/>
            <end position="1650"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="1656"/>
            <end position="1673"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="1680"/>
            <end position="1699"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="1711"/>
            <end position="1733"/>
        </location>
    </feature>
    <feature type="domain" description="Putative ER transporter 6TM N-terminal" evidence="9">
        <location>
            <begin position="286"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2421" evidence="8">
        <location>
            <begin position="1859"/>
            <end position="1973"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="67"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="227"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="554"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="742"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="842"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1031"/>
            <end position="1051"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1265"/>
            <end position="1304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1318"/>
            <end position="1371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1441"/>
            <end position="1546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1768"/>
            <end position="1849"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="2281"/>
            <end position="2355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="2382"/>
            <end position="2408"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="2120"/>
            <end position="2182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="23"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="71"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="97"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="125"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="136"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="266"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="570"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="595"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="640"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="745"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="855"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="869"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="891"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1265"/>
            <end position="1281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1321"/>
            <end position="1333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1350"/>
            <end position="1363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1477"/>
            <end position="1496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1795"/>
            <end position="1816"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1839"/>
            <end position="1849"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="2281"/>
            <end position="2298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="2308"/>
            <end position="2327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="2332"/>
            <end position="2343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="2344"/>
            <end position="2353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="2385"/>
            <end position="2399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF10334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF10337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0022359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="2408" mass="267281" checksum="91D53F4C1F89A27F" modified="2023-09-13" version="1">MPHSRAKQDSPRHGSPTNQTNDLKGHPLDSNHHNFTNPTNAIPRGNGYQAMSIPMPASSLVNFSLLSNNGRRSEDGTAHNGSDHTRPRSASTATTSDNRQSKNQSKNLKHPKSPKSDPSTPTAPLSITFNPLTPLNGSNNAKNKANKNNSYSKSEPNSRSSSTPSTPGEGPMGTGGYNNYHTIHHHLDLGVFHPLSMTHSQRVHLSNALAPNPLPESRSKGFDMSIFEPQPTSTRTSVDNEERNHRRAISRQPSMESFSSSNSVPLAPPPPPPPSAWKRFTSRFTQRVIKRHIKFGIALYAACLMILIRPIVDHLGTAPHLAAVGVIFMHPSRTVGAQLEITVFSLIGAVLAAAWVIPCEAAVAAFNDAYLSEGNKAAWAIDASWFFIGIWIMTAFKVKYAKLGTTFLVFAIILTFTLTKNNTSTEFRFYDFWNLAGPLLLGIGISQIANLLFWPETASENSSRALLGLSTRSFLLNHKTIALPNTVIEKAQAEVRTAQKKLFNAYREARYELTYSFVNPADYKQVRLILSNLMRHLGSMSLVVQNERILMLGHPDDDGDDLLSQSGSESDNDSTESDSEGDDESTDQETEDGHPSSSNRKTASRPISRQQSNDYFGTTAGHNNSNETSIDSPTSDAGRNSRKQSKRKSSAAELRRIRQLLQRAENATQAALAAKRQQQERMQKEGLQQIFQFDRGGVSTEPSTPVARGSSSIFDLYHTHRSKSSLLHANTNDSSLGAHRAHAFSHWSPNSSRPSSIHEEQSQETVKSFKSLFSVKSKSKFKPDRPLSLKAGFKIGQGKMPKETPNGSRDVSASPSVDYLPGIPLDRAHCNTVPARLGWKSESNSPNHSIHRSNGFLSRSPVTANQIKKAAESYRRQREKEAKLERKKAKKAAEAERKRTENEKEADAARLSDTCSRVMVGMERELVSGLSAERDRLERIKIRNAQRVDAIRAAEARIAADKKAAAAAANGASANLGKTSAKAEGGANIETSPRKPTALARLLEMVGIRPYQLTAEDIAYAEVLKTTMRKENERATKSNGSNGGGAANLANASNHNAQRNATSSAVDFENDFALPSDVSYVEYLTQELEIFDRAEAEGLRNFISTHPSLDIGPREELFLIFFFLFALREIACELLRLGKYIEKLEEQELKKMQEEHRLKPKKKLWWPKVMGNFWRWFSWGGYSQVKINENPVMLIPTKNIEQQTRTVEEEKAILEAKAVKAAAAKVALEKQMGQRRRRHSEMWDTPSLRRSVTVSALVFRGRQHPDLEQGLDRPRLEPQRRSREHRSRSVSADLNNVRSRSHTSLRNRLSHRFWHHETDFDNGNNTDSVQPQPDSGDPMINKVLTRQLGDHTTQTPVETSPGASSSTKKKSKLAEQYTVAEIPRFKVLHHKADKSLKHFEDINLVDLNPRVNAIKLHGTAPPELDIARSSGLTELHKFNDAARSGEDVTSTQSVALQDHDDIGIRPLRHTTNLSDSDNDHHGGTECEGSDMSHRSLDSQYHNPENSKPRSHGIFGVFNRRDKLDASDSPLKKQKRDQSPALEPSVSPKTMTVVVKRPKRFRYRVWEFLQPFKSDAIKFGFKMALSLTLVGLWSWLNWDSKALVTDRSQWSMMTVLAVLTPTIGDMFTTGVMRILGTILGAVWAIVTYLALPNNPYVIAAMMLPIALVSIYLMMLSAHPKVGLIMMISYCSIVFTVYEGYTTESIYTVAYKRSLTVIVGLIVSIIVNSLFWPILARRQLRREIAVLIGRQGVLFAELINKVFAMDSSADAEPGKVQDDSNVNPEGDIDAGEGGTDFIERAAREEHEENRRQVLRGRDVPGSNYQNLDASEISERRKKVKDARESEGRTENRVTVANSDRLAFQHIEQQLQAKLMKIMELVELSVLEPKLKEEFPVKLYRKIVKCCQNILDRMVSMRMAAQLLSPEVRELISGSLNICRRDLIGALLLYFSVLSSSLASKSPLPPYLPSARMARLRLIYRVREVIAARQRETGQDHYTYIYYYAFTSALEEVIEELELLAILIKPLVGVTMEVVADTFSFGEPYYQAKAGYTGATQMNLSQNSNAGQPTQSFEAGAASGHQLVSGQCVYGSVLSHSAPGMINLSADSTCEAASGAEVARQHLQNQHKEHVQERQTLDEYQRMFTEQQRQYVQLLQQVQAQQQLIQQQQQQLLLQQQQLSDMSESGRSKPSVPKIFIDQPITPVVSTNSTVPVGGAPLPGILNVYGDFRDASANSMPMPPVVVMDESLLHSRHGRRYQEAVQLAQEASGVLTIEVPLPPAVATPAQTQVATGVTSSATASSRIKNGRTKSSDNTSFTSKPQSPPEANTRASGDPSRLHSDNIDSHPSHATASATSAGPVFDDTDTFNMSFGSGLIPEAPLPLHMIPMQSEQYSQGQTPQSEIGRQRSPEQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N292</accession>
    <name>A0A9P6N292_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Copine-8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">CPNE8_1</name>
        <name evidence="6" type="ORF">BGZ80_000127</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the copine family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000102">
        <property type="protein sequence ID" value="KAG0022495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N292"/>
    <dbReference type="OrthoDB" id="5855668at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005544">
        <property type="term" value="F:calcium-dependent phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071277">
        <property type="term" value="P:cellular response to calcium ion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04048">
        <property type="entry name" value="C2A_Copine"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04047">
        <property type="entry name" value="C2B_Copine"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037768">
        <property type="entry name" value="C2B_Copine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045052">
        <property type="entry name" value="Copine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010734">
        <property type="entry name" value="Copine_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10857:SF106">
        <property type="entry name" value="C2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10857">
        <property type="entry name" value="COPINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07002">
        <property type="entry name" value="Copine"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="C2" evidence="4">
        <location>
            <begin position="1"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="4">
        <location>
            <begin position="138"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="5">
        <location>
            <begin position="298"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="560"/>
            <end position="594"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0022495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="614" mass="68673" checksum="65E60C98D11F121A" modified="2023-09-13" version="1">MYQQPTIPLAVPTAPKLELKIKCRGLADLDILSKSDPQCFVFMMDPKTRTWCKDPIGKTEMILNKLDCDFVTSIIIDYRFETVQQIRFTIVDVDNHNNPSWTAQELIGHFDTEVGKIVGSRGRTLAGRIEHPQHRRSHRGTVIISAEEQSQSKKVIKFNIEATKIAKKGFFRSEPNSFFIIHRASENGVFSPIYQSPVVRSKINPIWVEFTIKEINLSNGDPNRPLKIEVKKFKDNGPEHVTIGNTPVFTFQELLNTSMPRSFPLSPMPAGTNLLIRRMIVTEPPSFLDYLAGGVPLNLVVAIDFTQSNGDPRHPQSLHFRNPSGENDYTRAIRSVGNILQCYDTDKKFPVYGFGGKVNGQVNHCFALNGNPQFPEVDGVDGILAAYWHALQYAELYGPTNFSPVINQTVAICNQHRSGFEEYYVLLILTDGVITDMDNTIRAIIEASRLPLSIIIVGIGSANFDNMNVLDADDEPLRANGVTMARDIVQFVPFRDFQAGAFGDEALAEAVLAEVPDQFVSYMTQHRVVPRPPPRADTIQAMNNGGVAYDRPVSVYSAPPRSPMASPTNYGVSLPPPDNRISFSGPSINRGPQAMYSDQYNQYSQNHQYNQYSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2F3</accession>
    <name>A0A9P6N2F3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">U1 small nuclear ribonucleoprotein C</fullName>
            <shortName evidence="9">U1 snRNP C</shortName>
            <shortName evidence="9">U1-C</shortName>
            <shortName evidence="9">U1C</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BGZ80_003035</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the U1 snRNP. The U1 snRNP is composed of the U1 snRNA and the 7 core Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP, and at least 3 U1 snRNP-specific proteins SNRNP70/U1-70K, SNRPA/U1-A and SNRPC/U1-C. SNRPC/U1-C interacts with U1 snRNA and the 5' splice-site region of the pre-mRNA. Interacts (via N-terminus) with TIA1 (via C-terminus); thereby promoting spliceosomal U1 snRNP recruitment to 5' splice sites.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">U1 snRNP is composed of the 7 core Sm proteins B/B', D1, D2, D3, E, F and G that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP, and at least 3 U1 snRNP-specific proteins U1-70K, U1-A and U1-C. U1-C interacts with U1 snRNA and the 5' splice-site region of the pre-mRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the U1 small nuclear ribonucleoprotein C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000178">
        <property type="protein sequence ID" value="KAG0021101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N2F3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000243">
        <property type="term" value="C:commitment complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030627">
        <property type="term" value="F:pre-mRNA 5'-splice site binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030619">
        <property type="term" value="F:U1 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000395">
        <property type="term" value="P:mRNA 5'-splice site recognition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000387">
        <property type="term" value="P:spliceosomal snRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000059">
        <property type="entry name" value="U1 small nuclear ribonucleoprotein C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03153">
        <property type="entry name" value="U1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000690">
        <property type="entry name" value="Matrin/U1-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003604">
        <property type="entry name" value="Matrin/U1-like-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013085">
        <property type="entry name" value="U1-CZ_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017340">
        <property type="entry name" value="U1_snRNP-C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31148">
        <property type="entry name" value="U1 SMALL NUCLEAR RIBONUCLEOPROTEIN C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31148:SF1">
        <property type="entry name" value="U1 SMALL NUCLEAR RIBONUCLEOPROTEIN C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06220">
        <property type="entry name" value="zf-U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00451">
        <property type="entry name" value="ZnF_U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50171">
        <property type="entry name" value="ZF_MATRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 9" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Matrin-type" evidence="11">
        <location>
            <begin position="4"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="92"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="108"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="194"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="236"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00046357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0021101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="245" mass="25459" checksum="3C833EB6610B890C" modified="2023-09-13" version="1">MPKYYCDYCDIFLTHDSSSVRKAHNAGRNHLVNVKTYYSELSPETTQSVVDTINRAYAESGTALPPQYSGFPQFGGPGGVYNPYRPPSYPALPPGMPPMRPGESGPNGLPPRPPMPPHMFMRPPPGAPPGQFPPPPPGFPAGAPFPPPGAPFAPPGSAPFPAPASGAPFPPPGQFPPGQFPPGQFPPAGQFLPPGAPGAPGAPPGPPGQFRPPFASIPSPTHSSAPPSGAGSVMNGDRKRRLEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N325</accession>
    <name>A0A9P6N325_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Chaplin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_011093</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000085">
        <property type="protein sequence ID" value="KAG0022812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N325"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005528">
        <property type="entry name" value="ChpA-H"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03777">
        <property type="entry name" value="ChpA-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51884">
        <property type="entry name" value="CHAPLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040134435" description="Chaplin domain-containing protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="Chaplin" evidence="2">
        <location>
            <begin position="30"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0022812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="126" mass="13407" checksum="F244E2DA4EE9B953" modified="2023-09-13" version="1">MTSRTMHFLILVIAVVISTMTCAAPISDTAAQEAASDSPSVPIHIPVNVCGNSISVVGILNPTFEIRCASTDLPRVTLNMPPTVAAKRPSQSQLMEITITKFPYKNSYSSKGDTDNTSFGGCFKSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3F8</accession>
    <name>A0A9P6N3F8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Spindle assembly checkpoint component MAD1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">MAD1</name>
        <name evidence="10" type="ORF">BGZ80_007981</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MAD1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000042">
        <property type="protein sequence ID" value="KAG0023799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3F8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072686">
        <property type="term" value="C:mitotic spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051315">
        <property type="term" value="P:attachment of mitotic spindle microtubules to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007094">
        <property type="term" value="P:mitotic spindle assembly checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.457.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008672">
        <property type="entry name" value="Mad1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23168:SF0">
        <property type="entry name" value="MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23168">
        <property type="entry name" value="MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1 MITOTIC ARREST DEFICIENT-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05557">
        <property type="entry name" value="MAD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75704">
        <property type="entry name" value="Mitotic arrest deficient-like 1, Mad1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0498">Mitosis</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="240"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="190"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="420"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="551"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="16"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="45"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="105"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="240"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0023799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="779" mass="89376" checksum="C0A3E039D1CA1D68" modified="2023-09-13" version="1">MSLPNGDPDLVRRFMNRSPSGQSSPGNSQEVRMPFAQKRSLHGAGTTSTNTNASPSGASSLNQAWPGADSPRSSLFGRVSSPSGKSSIAALDQENDIQNSRIRSRAVEPEEYEQTRKKLKDTEYELSSTRTELERRIITLEQAARESDILKKKLMARVDSLESDRRFLYEHEKSLNKKCQALEESSLEFKVSSNEIIKNLREENMDLKERFSQLREQNRATESELSHKVRTLTASLAHHQQTLAQTQDTSHSQSSLAEEKHQQLTEALSRVMELEDQNRQLKLNEQKLEDVARIEKELQNQVAYIKQLEGTNRQLTADCRHFKEMYRNVEVLKEEKAGLEQKLKMLDDLRVKCGMLEVRNDVLVKEKQQWTAFLERSDVTDFNSPYQLAKTIASLRGDIATLMEIKGGFEADIKHRDTYIHQLETQIENLKKKLIEQEDFCKKQASIARQHNRSKELALRQVENLKEQLKSYDVEETQLMGGTYDNQKNIRIQQLENLIQEYHTKLESAMFSSSDNQSIETSSLEATDSLQLLQSIQNDNATTFSQLSSEKQALFEAKLHLEQEVELLRKENASLDAKVLEHEIAIGAGAFNPATSRILELKDNPASRHQANADREVAVRDEGLIPAASYNRLMGDYERLLEKLSENTKRSKHLKESWTSKADEFLDAVRSLLRYKANFLDNSRVELISMYNPEEQHSFVFNSGLNDEGIMQLIGSGSQKYMEEHKETFDYWVNQLGSIPAFLSRITLDFVEQQAQQVLQDRQFQNEEYTQNSDMMMDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3M6</accession>
    <name>A0A9P6N3M6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Proline iminopeptidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_006831</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000034">
        <property type="protein sequence ID" value="KAG0023986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3M6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051601">
        <property type="entry name" value="Serine_prot/Carboxylest_S33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248">
        <property type="entry name" value="2-SUCCINYL-6-HYDROXY-2,4-CYCLOHEXADIENE-1-CARBOXYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248:SF2">
        <property type="entry name" value="PROLYL AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0023986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="444" mass="49951" checksum="EBF446B23371E60B" modified="2023-09-13" version="1">MADNLATKKSGYLRPGPIESFISNGLKAQDYYFDLPLKHTDSSCKETIVVFARRVIAVERQGDAEKLPWLIFFQGGPGFQGPAYNTGWVKMAAKKYNVLLLDQRGTGLSTAITVQSLSHFKTPQEQAEYFMQFRADSIVRDSELIRETLLGNGYNAVPASITAAYITGGIPPVFDSLETVYRKSYKSVVEHTERYYKRFPSDIKRVKKIMKYLATHEVKLPTGGTLTPRKFQQLGLNFGVSGGMDRVHALCLQAFVTLNGKEEMSSLFLTEMASQDQIPPIYAVLHESIYCDGPGVSSNWTASKLLNGEFKSTFKYSVEEFGQYEDDSSKLVYFTGEHMYDWMLDDYVSLQPLKECADILASYTAWPKLYDAEVLARNTVPVAAAMYYDDMYVARECSEKTARGIQGIRLWVTNEYMHSGLRDNEGVLTKLFKLVSGEIDVPIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3V9</accession>
    <name>A0A9P6N3V9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Borealin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_011489</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000093">
        <property type="protein sequence ID" value="KAG0022677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3V9"/>
    <dbReference type="OrthoDB" id="2392550at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018851">
        <property type="entry name" value="Borealin_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10444">
        <property type="entry name" value="Nbl1_Borealin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Borealin N-terminal" evidence="2">
        <location>
            <begin position="171"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="256"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="120"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0022677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="322" mass="36234" checksum="FBE4FA4FF13ED1CD" modified="2023-09-13" version="1">MPRPTLQSPHARSPRSNLVSSSYDTRNLPNPFQDTSSTRFASKKNLSVPATAPEASDTIPSSSFASASISTASSSDRSRAPPLRHGNSSSNLLLPNDQTKSDSSTLQQLYREGSRPSNTQLQQQQQQQQTNDRSLSRQQRDSNFAREHESDHEQGHDLEQENPLIYLTASQREAAVENLEIETMDRTQKLRASIGVLTNSLRFRSEAEFNRLPAAIRTMTVEEFWFTYNGSAKEYLEQQTAKKSVANTSFLRALGITDPKKKRETMGQSEESWRHKQKNEEGVERTSQSSARYKPYPGTGQSQPRHIARPFVDSRLGQSSNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N413</accession>
    <name>A0A9P6N413_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Pre-rRNA-processing protein esf1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ESF1</name>
        <name evidence="8" type="ORF">BGZ80_011179</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ESF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000087">
        <property type="protein sequence ID" value="KAG0022769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N413"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039754">
        <property type="entry name" value="Esf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012580">
        <property type="entry name" value="NUC153"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056750">
        <property type="entry name" value="RRM_ESF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12202">
        <property type="entry name" value="ESF1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12202:SF0">
        <property type="entry name" value="ESF1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08159">
        <property type="entry name" value="NUC153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25121">
        <property type="entry name" value="RRM_ESF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ESF1 RRM" evidence="7">
        <location>
            <begin position="203"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="domain" description="NUC153" evidence="6">
        <location>
            <begin position="652"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="246"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="444"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="661"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="18"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="91"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="167"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="246"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="273"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="453"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="482"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="515"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="525"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="585"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="622"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="632"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="683"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="722"/>
            <end position="731"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF25121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0022769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="789" mass="90192" checksum="9333342EBD3AA740" modified="2023-09-13" version="1">MAPRPKKGGNNEAATPIKDARFAHVHRDPRFMRPKNKDSKVTVDSRFSSMLKGKEFSSAPKVDKYGRKLQSSASDQQMKRFYQLQKGETGSDNEDEDEDEDEDKDEDEVEDEVEDEVEDEEEDEVEDEVEDEEEDEDDDVSVSGSDSEDEDVYDPMRGRGVISGSDSDSDIDEETAAELDAEAEAQEEEEEEEDDIPRGDESHRFACVNLDWDHVKSTDLFKVFSGFKPEKGAIRSVRIYPSEFGKERMEREEREGPPAEIFKKSGSKAKGSDDEESEDEEIDEKAMIKNQVEDGDEEIDNDALRQYQLDRLKYYYAVVDCDSVETAKAICDACDGAEYESSANFFDLRYIPDGMEFEDTPRDEAFGAPENYKPNEFTTQVFQHSNVKLTWDEDDADRIKVTRQKFSKHDLEDMDFKAYLASSDEDSEDEDDIEATKRRYRALLAGGNKGSDDSDADSDDDKNQEMEITFAPGLSEAAAELLEAKKKREQPVKEETSIEAYKRKEKERKQRKKEARAAKNKGSDESDDDSEDQGGEALFSDDEDERLMNDSYFAEEFAGGDMMIPGKGKKGGSDKKNNKKNKKRTKEERLEDNRKKAELELLMEDNRENNQHFNMKEIQKAEKKKNKKKNKGQNDKDKGEDLQDDFKIDVADPRFSALHESHHFALDPTNPSFKKTKAMTELLQERQRRTAAAHDENEKKLKQKHGDNNNNNNSGNKKKKNSNSNNNNDNNMPKIKVKGTFDDPSLSLLVDTVKRKSAMATEQSHNGKRANPKQEARNNKNNNKRPKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N474</accession>
    <name>A0A9P6N474_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Asparagine--tRNA ligase, cytoplasmic</fullName>
            <ecNumber evidence="3">6.1.1.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Asparaginyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BGZ80_005687</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>tRNA(Asn) + L-asparagine + ATP = L-asparaginyl-tRNA(Asn) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11180"/>
            <dbReference type="Rhea" id="RHEA-COMP:9659"/>
            <dbReference type="Rhea" id="RHEA-COMP:9674"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58048"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78515"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.22"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.22" evidence="3"/>
    <dbReference type="EMBL" id="JAAAID010000028">
        <property type="protein sequence ID" value="KAG0024140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N474"/>
    <dbReference type="OrthoDB" id="1931232at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004816">
        <property type="term" value="F:asparagine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006421">
        <property type="term" value="P:asparaginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04323">
        <property type="entry name" value="AsnRS_cyto_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00776">
        <property type="entry name" value="AsxRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000151">
        <property type="entry name" value="Asparagine--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000040">
        <property type="entry name" value="Asparagine--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1910.20">
        <property type="entry name" value="asparaginyl-tRNA synthetase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004522">
        <property type="entry name" value="Asn-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048952">
        <property type="entry name" value="AsnRS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00457">
        <property type="entry name" value="asnS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22594:SF16">
        <property type="entry name" value="ASPARAGINE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22594">
        <property type="entry name" value="ASPARTYL/LYSYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20917">
        <property type="entry name" value="AsnRS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="14">
        <location>
            <begin position="269"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="77"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00039867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0024140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="572" mass="63709" checksum="C0D1ACE72970C202" modified="2023-09-13" version="1">MADKLPVDSLSITSVVAHVDETKGSDETGNGSVEAPYQSAVKALQAHGDSVKIQVWKAAAAGTDETSGYVAISGAALKKAVKKVGELERKAAKAAEQAAELAAKEKAAAEERERVLEAAKLVVLKQDPSLPAATKIKIKNSVESRGKRVKVSGWVHRLRVQGKNMTFIVLRDGTGYLQCVLTDNLCQTYDALTLTLESTVTVYGVINELPAGKTAPDNHELTVDYWECVGKAPGGEDAISNKVNENSDPSVKYDLRHLVLREEKASGILKVRSTVMKAFRDHFDSRGFLEVTPPAMVQTSVEGGSTLFELNYYNEKAYLTQSSQLYLETCLPSLGDVYCLAESFRAEKSHTRRHLSEYTHCEAEMAFISFDDLLAQLEDMICDVIDRTLAHKPSADIIYKLNPEFKKPERPFMRMDYTDAIQYLKDNDIKKEDGTFYEVGEDIPEAPERAMTDKINRPIFLCRFPAEIKSFYMKRCPENPALTESVDVLMPGVGEIVGGSMRISDLDELMAAYKREGLDPTPYYWFTDQRKYGTSEHGGFGLGVERYIAWMLNLFTVRDTCLYPRFTGRAFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N477</accession>
    <name>A0A9P6N477_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_010513</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000074">
        <property type="protein sequence ID" value="KAG0023052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N477"/>
    <dbReference type="OrthoDB" id="10265800at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004620">
        <property type="term" value="F:phospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006644">
        <property type="term" value="P:phospholipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001087">
        <property type="entry name" value="GDSL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038885">
        <property type="entry name" value="PLB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21325:SF31">
        <property type="entry name" value="GH22081P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21325">
        <property type="entry name" value="PHOSPHOLIPASE B, PLB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00657">
        <property type="entry name" value="Lipase_GDSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0023052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="332" mass="36504" checksum="198EBA2ACEE9B4B0" modified="2023-09-13" version="1">MPWVNELQGLYNMFGEARNETSCPTQIPDWKCKPYELTEQDLNTPLNVWRLRPHDIKAVISIGDSITAGFAMISGRPPFATVLEFRGKVFSGGGDDGEYTFANFLKTYAKHVKGSPSGFTLPLTTGKGLNTAVSGAIVQSLPSQVERLKRLFGFGGSYHKYKNEWKMATVFIGANNICAACGQGETIPEIADPEEYGAALKSTLLKLKESIGPAFVNLVGIFDVSLVYDLSRGYDYCEMLFDKMPLPICGCATGNEADRQRAGTLAREYNEVMKRIALEINEESANGGTFGVVYQPGLTEFRDGSSPYGQGYLSGLDWYVNVIEVTLIKFLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4K0</accession>
    <name>A0A9P6N4K0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="6">PPIase</shortName>
            <ecNumber evidence="6">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">CYP1</name>
        <name evidence="9" type="ORF">BGZ80_000009</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 6">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the cyclophilin-type PPIase family. PPIL1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="6"/>
    <dbReference type="EMBL" id="JAAAID010000001">
        <property type="protein sequence ID" value="KAG0024881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N4K0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000008">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3730.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044666">
        <property type="entry name" value="Cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625:SF4">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE DOMAIN AND WD REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0697">Rotamase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="55"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="110"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="8">
        <location>
            <begin position="124"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0024881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="268" mass="29310" checksum="D99241707CB73D67" modified="2023-09-13" version="1">MLPENAIGFILVALCWGFTNPFIKNGSKGLESIKRDSWLSQAAAEYWYLFTRWQYVVPLVLNLCGSVVYYHTLGKADLSLAVPITNSLTFIFTTLAGILLGESIGSPRSWLGMAMVVLGVGLCGEITIELYTEHAPKTCKNFYELARKGYYNDVVFHRIIPDFMIQGGDPTGTGRGGSSIYGDKFADEFNSALKHTGAGILSMANSGPNTNGSQFFITLAPTPWLDNKHTIFGRVSGGIKVVNRMGLVATDANDRPKEAVKIIRARVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4X2</accession>
    <name>A0A9P6N4X2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Vacuolar protease A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">PEP2_5</name>
        <name evidence="4" type="ORF">BGZ80_007708</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000004">
        <property type="protein sequence ID" value="KAG0024773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N4X2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF51">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase A1" evidence="3">
        <location>
            <begin position="32"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0024773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="144" mass="15664" checksum="3DC0E975457806D7" modified="2023-09-13" version="1">MSQAERPWTSRVSTSGRARPVEEKRRSGTLKYYAEIGIGTPPQIFKLDIDTGSGNIWVPDQKRVVCAKNAKFNPQIPSTHKPEGLRWSNSYDDGLSASGCIIQDAVTLGPISVPNQFIGLATDGSLAHQSNAVDGLLSLSFFWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N5B4</accession>
    <name>A0A9P6N5B4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">U3 small nucleolar RNA-associated protein 13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">UTP13</name>
        <name evidence="8" type="ORF">BGZ80_007131</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000036">
        <property type="protein sequence ID" value="KAG0023944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N5B4"/>
    <dbReference type="OrthoDB" id="5414888at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034511">
        <property type="term" value="F:U3 snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000480">
        <property type="term" value="P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000472">
        <property type="term" value="P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000230">
        <property type="entry name" value="Transducin beta-like protein 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013934">
        <property type="entry name" value="Utp13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19854">
        <property type="entry name" value="TRANSDUCIN BETA-LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19854:SF15">
        <property type="entry name" value="TRANSDUCIN BETA-LIKE PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08625">
        <property type="entry name" value="Utp13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="63"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="105"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="147"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="191"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="260"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="375"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="425"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="479"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="521"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="563"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="605"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="domain" description="U3 small nucleolar RNA-associated protein 13 C-terminal" evidence="7">
        <location>
            <begin position="658"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="844"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="844"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="864"/>
            <end position="892"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0023944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="892" mass="99125" checksum="D4DD248001EDF496" modified="2023-09-13" version="1">MAAQAPPQGKIHLKTSFKSTQTIESIYTGGKVCISQDEQYLITTVGEDIDVIEIKTGKKLWRLKGDTEIITTFAVTPDGHTLISASRSLQLKTWNLRTGTLTRSLKAHDAPVIVMNIDPTSTLVATGSADSTIKVWDIAGGFCTHNFKGHGGVISAVLFHPDQSKWWLCSGADDCTVRIWDLKSRKSVAVLESHVSVIRGLAVSNSGKSLISGSRDKVVNVWDLTSMKLATTYPIYETLETVGILQKSKIEAIGSKDVADKEMFYTAGDSGVIKIWDLKSGELIAKQKEEQGSKSGISDVLYNKESQQLVSITSDQNILFFNIEDGLKRVKQIVGYNDEIVDVAYIGEEENHLAVAANSEQIRVFNLKEFECDLIYGHTDIVICLDKNTDGTLLASGSKDNTAKVWTLDLENEDADERYKCIGTCVGHTEAIGAVALTRKTDGLLLTGSQDRTIKCWDLSTGDLDNPDEEHRFKSHYTIQAHEKDINSIAIAPNDKIFATGSQDKLAKIWNLQEGTLMGTCKGHKRGVWSVKFSPVDQCLATSSGDRTIKIWSLNDFSCLRTFEGHTNSILKVDFLTSGLQLVSCGSDGLVKLWTIRTNECVATLDNHTEKIWALTVRRDENMVVTGGADSMINLWEDFTEIEYAEKKQAQADQVLKEQELSNYLQRKDWKNAITLALSLEQPFRLLQLFNQILRDRPEHDTSITGLAAVDKVLKGLSLDQIAKLLGYVRDWNTHAKNMRAAQTVLHAILRERKVQEMIEVPGIKDLLDGLLPYSERHFQRVEALSVRSYVVDYTVQAMDMMTMMGDMDDLELEMDEGEDRLSLRAQRKAEEERMAKERHEAFAAARAATETAPITNGATAIVEDGEEEEDDAADDESAGEVEEGDSDEDME</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N5N5</accession>
    <name>A0A9P6N5N5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Amidophosphoribosyltransferase</fullName>
            <shortName evidence="8">ATase</shortName>
            <ecNumber evidence="3 8">2.4.2.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Glutamine phosphoribosylpyrophosphate amidotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ADE4</name>
        <name evidence="12" type="ORF">BGZ80_004290</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>5-phospho-beta-D-ribosylamine + L-glutamate + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + L-glutamine + H2O</text>
            <dbReference type="Rhea" id="RHEA:14905"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58681"/>
            <dbReference type="EC" id="2.4.2.14"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="10">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Purine metabolism; IMP biosynthesis via de novo pathway; N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.14" evidence="3 8"/>
    <dbReference type="EMBL" id="JAAAID010000022">
        <property type="protein sequence ID" value="KAG0024328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N5N5"/>
    <dbReference type="OrthoDB" id="191723at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004044">
        <property type="term" value="F:amidophosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009113">
        <property type="term" value="P:purine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006164">
        <property type="term" value="P:purine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00715">
        <property type="entry name" value="GPATase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01931">
        <property type="entry name" value="PurF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005854">
        <property type="entry name" value="PurF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035584">
        <property type="entry name" value="PurF_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01134">
        <property type="entry name" value="purF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11907">
        <property type="entry name" value="AMIDOPHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13522">
        <property type="entry name" value="GATase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000485">
        <property type="entry name" value="Amd_phspho_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="4 8" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="11">
        <location>
            <begin position="2"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="308"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="370"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="371"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR000485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000485-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000485-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0024328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="513" mass="56251" checksum="34292D0DD46D5958" modified="2023-09-13" version="1">MCGITALLLADPNLMASPELHEGLGMLQHRGQDAAGIVTCGNKGRLYQIKGNGMVRDVFDQPKLEQLVGSMGVGHVRYPTAGSSSTSEAQPFYVNSPYGIVFAHNGNLVNADELRHFLDQDAHRHINTDSDSELLLNIFANNLQKTGKFRISEEDIFTAIKGIFDVCHGGYACVAMIAGFGIIGFRDPHGIRPIGFAKRSSPKGTDYMFASESVVCDGCSFSDFEDLKPGEAVIVSKAGVVTRRELVENANFSPCIFEYVYFSRPDSIIDGISVYKCRLAMGEALADQVIKKLGPNNDVDVIIPVPDTSRVAALQTAYKLDITYREGFIKNRYIGRTFIMPGQAMRKKTVRRKFNAMSLEFAGKNVLIVDDSIVRGTTSKEIVQMARDAGAKKVYLASCAPAIRYANVYGIDMPSPQELIAFNKTEDEIAEALGADQVIFQTLEGLIASCQKFNPSITSWDAAVFDGKYVTGQVDAAYLQHLEDLRSDGKKGKSEHTQSPETLGLYNFNLQLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SR84</accession>
    <name>A0A9P6SR84_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_008409</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004545">
        <property type="protein sequence ID" value="KAF9992785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SR84"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036157">
        <property type="entry name" value="dUTPase-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51283">
        <property type="entry name" value="dUTPase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9992785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="105" mass="11742" checksum="4F0460C56696E630" modified="2023-09-13" version="1" fragment="single">QVPARSLDTIDLYSPYNIKLEAGNEVHIKTGVVCAIPEAGLVLKARISLNFENSLIIHAYMMKHNKEIAVFAWNIGFEVVWLSKDRPIAQLTMVNKADSDSDDDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SRR1</accession>
    <name>A0A9P6SRR1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Multicopper oxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_007674</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multicopper oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003973">
        <property type="protein sequence ID" value="KAF9994858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SRR1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13886">
        <property type="entry name" value="CuRO_2_MCO_like_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.420:FF:000045">
        <property type="entry name" value="Laccase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001117">
        <property type="entry name" value="Cu-oxidase_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709:SF414">
        <property type="entry name" value="ADR239WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="MULTI-COPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00394">
        <property type="entry name" value="Cu-oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0186">Copper</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Plastocyanin-like" evidence="4">
        <location>
            <begin position="3"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="3">
        <location>
            <begin position="83"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9994858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="369" mass="40842" checksum="6B10F062CDEE69AD" modified="2023-09-13" version="1" fragment="single">MVNGTSIHWHGMFQNGTNWMDGTTGVTQCPIPPGQSFTYNFTVPNQWGTYWWHAHAASQYVDGIVGPLIIHSPDEPHLGTYDEDIIMMISDYYHTDSGSLVSWFLSAESQGVEPVPDNGLINGRNSFDCTGDSKALFPTGSKCHSNAPLSVFEFNSGLTYRVRIINTGSFADFHFSIDNHTLTVIEADGVDMQPVDVQRIPIHVAQRYSALVHANQTVGNYWVRADMNTNCFNVDNPALNPNVPAIIHYEGAPSSQEANSKDWGTSAWTPYCLDLTSDMLKPALAMDAPAADMQIYMDISFQTITQSQVNLAYVNQTSWVPLMDNATLFQANRGVSTFDSSQLIVTLNTTQTVELIVNNYDDGSHPFHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SS70</accession>
    <name>A0A9P6SS70_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_007353</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003742">
        <property type="protein sequence ID" value="KAF9996080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SS70"/>
    <dbReference type="OrthoDB" id="2342079at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.80">
        <property type="entry name" value="Galactose oxidase/kelch, beta-propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037293">
        <property type="entry name" value="Gal_Oxidase_central_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32208:SF21">
        <property type="entry name" value="LOW QUALITY PROTEIN: ALDEHYDE OXIDASE GLOX-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32208">
        <property type="entry name" value="SECRETED PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9996080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="106" mass="11123" checksum="DF077BC2DBB1B364" modified="2023-09-13" version="1" fragment="single">MPSLPKGSFKVVGNSGVTAQHIALVTPTKMLIIDRAEENPPKLPSGKSAYNAEYDLIRNDFRVLEVQTNTFCSGGGFLPNGTMISAGGAEIPHFGGVKAGTGFQSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SSL4</accession>
    <name>A0A9P6SSL4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Kinase-regulated stress-responsive transcription factor skn7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">SKN7_2</name>
        <name evidence="8" type="ORF">BGZ80_007075</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the HSF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003560">
        <property type="protein sequence ID" value="KAF9997141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SSL4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000027">
        <property type="entry name" value="Heat shock transcription factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF361">
        <property type="entry name" value="TRANSCRIPTION FACTOR SKN7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00056">
        <property type="entry name" value="HSFDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00434">
        <property type="entry name" value="HSF_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="7">
        <location>
            <begin position="33"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9997141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="164" mass="19081" checksum="E98A622C71EBAA02" modified="2023-09-13" version="1" fragment="single">MLEEKEHDPIVSWGKSGETFVVKEPNEFAKVILPKHFKHNNFASFVRQLNKYDFHKIKTTEDSTRPYGDQAWEFQHPKFQVDKRDLLENIKRKTPSNKKLQTPATVGTTQDHQPAIIEEYQVQMEQLVKSQAKMQADLTKCEAKIKAQEQLIHQLIGLLGFTFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ST11</accession>
    <name>A0A9P6ST11_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase</fullName>
            <ecNumber evidence="5">2.7.8.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">GlcNAc-1-P transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="16">N-acetylglucosamine-1-phosphate transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="primary">DPAGT1</name>
        <name evidence="21" type="ORF">BGZ80_006648</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. Catalyzes the initial step of dolichol-linked oligosaccharide biosynthesis, transfering GlcNAc-1-P from cytosolic UDP-GlcNAc onto the carrier lipid dolichyl phosphate (P-dolichol), yielding GlcNAc-P-P-dolichol embedded in the cytoplasmic leaflet of the endoplasmic reticulum membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>a di-trans,poly-cis-dolichyl phosphate + UDP-N-acetyl-alpha-D-glucosamine = an N-acetyl-alpha-D-glucosaminyl-diphospho-di-trans,poly-cis-dolichol + UMP</text>
            <dbReference type="Rhea" id="RHEA:13289"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19507"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:58427"/>
            <dbReference type="EC" id="2.7.8.15"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="18">
            <dbReference type="Rhea" id="RHEA:13290"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyltransferase 4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.15" evidence="5"/>
    <dbReference type="EMBL" id="JAAAID010003291">
        <property type="protein sequence ID" value="KAF9999057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ST11"/>
    <dbReference type="OrthoDB" id="10262326at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003975">
        <property type="term" value="F:UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006488">
        <property type="term" value="P:dolichol-linked oligosaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06855">
        <property type="entry name" value="GT_GPT_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000715">
        <property type="entry name" value="Glycosyl_transferase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033895">
        <property type="entry name" value="GPT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10571">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE--DOLICHYL-PHOSPHATE N-ACETYLGLUCOSAMINEPHOSPHOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10571:SF0">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE--DOLICHYL-PHOSPHATE N-ACETYLGLUCOSAMINEPHOSPHOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00953">
        <property type="entry name" value="Glycos_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14 20" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 20" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 20" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="78"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="122"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="154"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="181"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="251"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="282"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="474"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="398"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="19">
        <location>
            <begin position="409"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00029567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00033238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00044717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00045078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAF9999057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="503" mass="55702" checksum="C2D6212413E82F0F" modified="2023-09-13" version="1">MGQISAFTAWLILAAVVGAVFIILTTAHDPFTVNSGLSVLAGIVTWSSIPALSEIFVKAGLKGMDLSKKTKNIIPESMGMVAGLIYLVTMFVFIPFPFMRWFTDGNQELTLLTFPYLKLAELLSALLSIQSMVFLGFADDVLDIRWRFKMPLPAVASIPLLMVYWVNAGVTYIVVPIPLRPFLGHLIDLGVLYYIYMGMVAIFCTHSINIMAGINGVEVGQSLIIACSIAANDLHFINSPSTLAPAIETHLFSLYFIMPFIGVSLGLMIHNWYPSKVFIGDTYCYFAGMTFAVVGILSHYSKTLLLFFIPQIFNFILSSPQLFRLVPCPRHRVPRYNRGTNLMEPSHVVLDQEGLDEEISQNIAQGHLTQTQQRSGTLGKPASSASLLSSTVELEDQASVAAKNPPPSSEIQHTPRPNSGLSRPGLLCIKILELLRLTHVRYDSRTGQRPLEMTNLTLLNLILLKAGPTSERNLTIYVMIIQVICSAIAFFIRYRLAAFVYDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6STB7</accession>
    <name>A0A9P6STB7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HAMP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_006467</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003194">
        <property type="protein sequence ID" value="KAF9999920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6STB7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004673">
        <property type="term" value="F:protein histidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071474">
        <property type="term" value="P:cellular hyperosmotic response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06225">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1530:FF:000003">
        <property type="entry name" value="Atypical/HisK protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1530">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45339">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45339:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18947">
        <property type="entry name" value="HAMP_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58104">
        <property type="entry name" value="Methyl-accepting chemotaxis protein (MCP) signaling domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="domain" description="HAMP" evidence="4">
        <location>
            <begin position="367"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="4">
        <location>
            <begin position="454"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="4">
        <location>
            <begin position="546"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="126"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="168"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="127"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="168"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="230"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9999920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="643" mass="67839" checksum="EBCBC1ED86774DF0" modified="2023-09-13" version="1" fragment="single">MAATLTDAYMDHVGNILDMLAQDRTLDPISLSFASSSSTPLVPAFVDAETQSPLIHKVDVALQRVVQKMFFMEHELARHRKECLATSKGHHYYTHSGGLPPIVAPILTPPVDPLSSPMSASLRWSEGTATWETTSHDPSLPTPNPNPSLLSIQSLSSAVALSADNHSLSSGSVMHTSSTSSSSSLHDNASGSEKSTTPTASTISSTAELPIATGTSTTTTTTTAPGDFLSTTSLVPSTPSSPDSFCSANSGFPPDDTDTVSTLAPVLDVGPCPVCIRNCALVASAVVRGDLGVRISCKREACNHSALTISINQMVSKLANFTTEVIQAAAQGVEGKLGVQAKIKDEHGIWKEFVSHLNTMTVGHSEQVRDIASVCTAVAHGDLSQKITVPVKGETLVLKNTINTMVDQLRSFSSEVTRVAHEVGTEGKLGGQARVEGVDGTWKELTDNVNTMAANLTAQVRDIANVSKAVAKGDLSKKISVEVKGEMMDLKNTINTMVDQLQEFATEVSRVSLEVGTEGKLGGQAVVKDVSGTWKELTDNVNLMASNLTGQVRDVATVCKAVAAGDLTKKVIVPVQGEILELKETVNTVVDQLRTFAAEVTRVAREVGTEGKLGGQAEVEGVDGTWKELTDNVNTMAANLTAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SU08</accession>
    <name>A0A9P6SU08_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ricin B lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005976</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002946">
        <property type="protein sequence ID" value="KAG0002436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SU08"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14200">
        <property type="entry name" value="RicinB_lectin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ricin B lectin" evidence="1">
        <location>
            <begin position="43"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0002436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="134" mass="15618" checksum="0A939E53D8CA9709" modified="2023-09-13" version="1">MTHPQLPQTAIRLRNLRHGTMLYDNVQSGLIPWQESTNPDGYWYITHVTENTYKIKNRQSGNCVYYNVDKKKPITWRDSANGDGVWEFVPTSIVGQYRIRNVLTPTMYLYHNHDHGIIGHMDNGEDDGIWAIKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWT2</accession>
    <name>A0A9P6SWT2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Cyclin-dependent serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">CRK1</name>
        <name evidence="12" type="ORF">BGZ80_002917</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001747">
        <property type="protein sequence ID" value="KAG0008912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWT2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07829">
        <property type="entry name" value="STKc_CDK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000144">
        <property type="entry name" value="Cyclin-dependent kinase 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000624">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF46">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="6 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 12" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="6"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0008912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="244" mass="27546" checksum="76B9AA792DE34A91" modified="2023-09-13" version="1" fragment="single">MGRGKQKKIEKLGEGTYGIVYKAQNRETNDVVALKRIRLDNEEEGVPCTAIREISLLKELRQNNIVRLYDVLHTEKKLTLVFEFLDSDLKKFLDTYSGDIDVLTIKDLKPQNLLINKKGDLKLGDFGLARAFGIPVRSYSHEVVTLWYRAPDVLMGSKQYSTSIDIWSAGCIFAEMASGRPLFPGSSVKDQLLKIFKILGTPSEETWPGVSRLPEYRPDFPLYNPIPLENLIPKLDASGIDLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWW6</accession>
    <name>A0A9P6SWW6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Arm-like repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_002764</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001699">
        <property type="protein sequence ID" value="KAG0009067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.80">
        <property type="entry name" value="E3 ubiquitin-protein ligase SopA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056251">
        <property type="entry name" value="Arm_rpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050505">
        <property type="entry name" value="WDR55/POC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44019:SF8">
        <property type="entry name" value="POC1 CENTRIOLAR PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44019">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23948">
        <property type="entry name" value="ARM_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141571">
        <property type="entry name" value="Pentapeptide repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Arm-like repeat" evidence="5">
        <location>
            <begin position="272"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1317"/>
            <end position="1358"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1359"/>
            <end position="1400"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1409"/>
            <end position="1443"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1459"/>
            <end position="1491"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1492"/>
            <end position="1533"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1534"/>
            <end position="1575"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1576"/>
            <end position="1603"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="86"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1071"/>
            <end position="1105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="90"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1081"/>
            <end position="1090"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1091"/>
            <end position="1101"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1603"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF23948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0009067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1603" mass="179919" checksum="35B71ACF1EAA8EEA" modified="2023-09-13" version="1" fragment="single">MVWCPCSSPRTVEEILNDVDKRLEKANHVDNKSKLKLCRKAEKGMKKADKQLKSEGNNKFSRGRIARAYHSHSILLESLGDHAAAQKSKKLAEERGYERAVNEGAHSSSLGSATTTILTPQHVAAESKVETILPSPQPAIKNDKEYSTGPEPKTKTTHLYLQPTVTILSTYDISKSEQASLNDVALPLPQSEPTEAGHTPMDIVEPFSQTSAIPRASKLIFASVTTPPVAKHELPRAGELIKDTAQLAYCLNLMNTASPYSLSLDQVEQNWLSSINEAPQEKKRLQTLASDLVRTFVRDEIKGPDSVKEIVCLAPVLGQEDFRRLLHTIVDGINNTLLQDNYLLDGLAQLIRNSSLEHLDVNDLVKILKLLSEKLQGTHWESAHQYHSALTISRVLDVMMDTKVKDIHREDLRSPLLEFLKKLRWDTDPYLAFQGTYAYQALLYIPDDESTTQEVLRRAGKVVQGISGIVSAVKAVDLNHFVGSLNHIQQGLSGVVPSFETVFGAVKHSLALVESGQSFIDCIKEGFSSDRKSVWYPALRGLDIFIQEGRFIVFEELIRVAPCRKHPLFQWGVCQRLGEIANNPFWDTNVRNCAIKFLLEIYKDDVAWNPQLTVKQWILYILNQLEKPSDEFLARHIQELYQQSSLVGIFTKPYPLVKPLQPNVFPLLSRVQAKPETPDVEAALRKLKYERLSGQGDDIYVKPKATATTQTTESFDLMAKAQEFLRSKKTVLLLRGSSGSGKSTFNRALEIHLWETYVVGGAIPLFIELPAIENPKEDLVVKQLRKADFTDNLIKELKEHRNFILICDGYDESQLTENLYLKNRLNQIGEWRAKVVITCRTEYMSHEYKSLFLPEGRNNTRESKLFDEAVIAPFDDDQIREYIGQYALKANPPLDAATLMKTLEKISDLQDLVKNPFILKNSLEVLPQIEEASKIHATARFTKVELYDNFVLQWLERNHTRIQEMKLGADDEAAFTKLLQGGFTKRAFRFLADLAAAIYTEQEGNPVVQYSRFNNEDDWKDRFFSNSDGKNLLREAIPLTCSGDYYHFIHASYLEYGLSLAVFDPKVYEKHVEPPPTSQGNRRRDRRHRNSTNSTMANKSDTVSDKHLVDSPLGKIVLTGNRTTVDCLEFLVQRVQQYPMFKAQLLAVIEKSKFETSDRISIAAANAITILVKARISFNGVDFRNIKIPKADLSYGMFDSALLDGADLRGVDFRNIWLRGSSLSKVDMAGAKFGEFPFIKAVRHCAFSPDRSQFAVILESGDINLYDMSNWERIEILNTRSDQFSSITFPPRSNQIAFGGDKTVWIYDVTGSNPRNLEGHDDTISCVVYSPNGDQIASGSYDTTVRLWDADTSKSIHNLIGHTESITAIAFSPNGDTIASASEDFTVRLWDVESGACIHIFKDNTEYIITGVVYSPNGDRVASVNSVLKVKLWDVDAGECIHTWTNSISTEPLEKTSSSIAYSLRGDHIACASDDGTVKIWDVDTGELCRTLHGHNGRVTSVVYSPFEDLIASGGVDKTVRLWDVETDKCIHTFRGHSQDVSRIMFSPEGDCISSESSGKEVRLWHVDTDFSAHTGSSHTDEVHAVAYSPKGDRVASGSKDHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWY0</accession>
    <name>A0A9P6SWY0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_002946</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001752">
        <property type="protein sequence ID" value="KAG0008896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWY0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0008896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="225" mass="25335" checksum="105722D47A0CDD0B" modified="2023-09-13" version="1">MVKYCRTGNKWILAPLSPVEDKFLTFTEIELAAFSAKREDLHEDVKDLICLKSDRRLTQADIIRHPAPGLPDRSQRSPRPQETQRRCGHGHQNAHPNAIREHINMLRGQDFDPREYVEKGYALRGSIKTDGPPSLRNSTTAGTGDPLTEMRNVFKSKEDVERLFGCTTDQADAISFLGIDLGQTCVVGAYSLLPADKKPQNGRRNNKGSRGRRRRGSKQAKEKNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SX11</accession>
    <name>A0A9P6SX11_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Sulfurtransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_003301</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001867">
        <property type="protein sequence ID" value="KAG0008556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SX11"/>
    <dbReference type="OrthoDB" id="566238at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004792">
        <property type="term" value="F:thiosulfate-cyanide sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001307">
        <property type="entry name" value="Thiosulphate_STrfase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44086">
        <property type="entry name" value="THIOSULFATE SULFURTRANSFERASE RDL2, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44086:SF10">
        <property type="entry name" value="THIOSULFATE SULFURTRANSFERASE_RHODANESE-LIKE DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00683">
        <property type="entry name" value="RHODANESE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Rhodanese" evidence="2">
        <location>
            <begin position="23"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0008556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="125" mass="14271" checksum="7EC2ACBDC853976F" modified="2023-09-13" version="1">MAIHQDAKLEEATFEEIQALIQQDNRAPLIDVREPAEVALGIIPTAHHIPLADLKDALVTLSDKAFEDQYGFKRFAKDDEAIFYCRSGRRSRLAFAQAKELGYTHVRHYPGSWIEWEARTKDSSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXA0</accession>
    <name>A0A9P6SXA0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Eukaryotic translation initiation factor eIF-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">SUI1_1</name>
        <name evidence="4" type="ORF">BGZ80_002388</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SUI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001587">
        <property type="protein sequence ID" value="KAG0009441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXA0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11566">
        <property type="entry name" value="eIF1_SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.780.10">
        <property type="entry name" value="SUI1-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001950">
        <property type="entry name" value="SUI1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036877">
        <property type="entry name" value="SUI1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005874">
        <property type="entry name" value="SUI1_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10388">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01253">
        <property type="entry name" value="SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004499">
        <property type="entry name" value="SUI1_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55159">
        <property type="entry name" value="eIF1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50296">
        <property type="entry name" value="SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SUI1" evidence="3">
        <location>
            <begin position="10"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0009441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="92" mass="10523" checksum="15C8D412BF3BCE89" modified="2023-09-13" version="1">MSDIQNLQTYDIRIQQRNGRKTLTTIQGLPKTFDQKRMLKVFKKDFACNGTLVDDEELGSVIQLQGDQRTKVLNLLTTEGGIDKKQIKIHGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXE9</accession>
    <name>A0A9P6SXE9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cationic amino acid transporter-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ATRC1</name>
        <name evidence="7" type="ORF">BGZ80_002264</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001553">
        <property type="protein sequence ID" value="KAG0009569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXE9"/>
    <dbReference type="OrthoDB" id="5982228at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015171">
        <property type="term" value="F:amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43243:SF4">
        <property type="entry name" value="CATIONIC AMINO ACID TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43243">
        <property type="entry name" value="INNER MEMBRANE TRANSPORTER YGJI-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="59"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="192"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="218"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="258"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="300"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="344"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="396"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="424"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="455"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="479"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0009569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="632" mass="68143" checksum="782E08575C7EAB1A" modified="2023-09-13" version="1">MDDDEGYYYTGQTPFRKPNESKLHYHARRLVSIQTLSRLEYSVEEAESKFNRALGPVELTFVGLGAVVGTGVFVILGNAAATQTGPSVTVAFILGGIVSGIAALSYAEMASMIPIAGSAYTYAYATVGELPAWIIGWNLILEYMVGAATVSVGFSSYFVVFVSDAFGQNLSSKWTNAPIIWDENDFRMSGDYFNTPAFVISILVTTTLYFGIRFTAKLNNVLVAFKMVALTIMIFAMIPSIKNENYHPYIPPNTGTYGQFGATGLLQGASSVFFAYIGFDSVSTTAQEAKDPQVNLPIGIMMTLIISAIVYIAISAVTVGVANYLDLGGGSPLVYTVRLTGMRWLVILTELAALAATISVIVVLLISQPRVFYAMSNDGLIPRVFSRVHPRYKTPYVSTLVSGILSAFFGALLPIGVLSDMSSVGTIMAFFVVNIGVIILRYTRKTVPRRFKVPGGPLLLPGIGAASSLLLLQGAKREAIIRLLVWMAVGIFVYVVYGRSHSEVNNPRPITDEPMRVLHENYSVNTLDQGGYIDDDLRRRLGITPYDIGQPCAEEGEEGSRQQSGISLGECLSQARESATEIQKPAAIARVGATEDDGQGCSSIGSSTAHEPVPQRVALADGGRSIIIPPQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXM5</accession>
    <name>A0A9P6SXM5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">t-SNARE coiled-coil homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BGZ80_001638</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the syntaxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001379">
        <property type="protein sequence ID" value="KAG0010257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXM5"/>
    <dbReference type="OrthoDB" id="342981at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019529">
        <property type="entry name" value="Syntaxin-18_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15959">
        <property type="entry name" value="SYNTAXIN-18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15959:SF0">
        <property type="entry name" value="SYNTAXIN-18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10496">
        <property type="entry name" value="Syntaxin-18_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="423"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="12">
        <location>
            <begin position="351"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="253"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="134"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="328"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="254"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="269"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="307"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0010257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="442" mass="48842" checksum="F24815F20B20BB74" modified="2023-09-13" version="1">MPDLTDIFRATVQDLDQAPGNMSKLRANTANQHQPDPWIKEAHQISRTMSDLRVFIITTRPAYLNISRGVGSSGINGSGRLQRISDSIPKNNNNTSSSGYNTITSSKVLNDLLETVSSLTSLSDKDRDSIDTQAKVMMRQIKGAIEELESLEQERRKRQQSSSNASVSGFNQLLNAAAQLGSSSGTIDDLAQHRQGVTLYLNERLASLATLHKDQYETRIAREMEKRESSLYKALPKPTSVAGTNSFGLRWNDTTTAGSLAPGGSSLSQRKNQGPDSFSNNGTLSPPSSSHGPHKGGSNKTDTSGISSSQYYQQQSSSSLGSGFVDEEQDFEASLTEQERQMLQLENENIVQKLETELNQVRQLESSMMELSSLHSTIQEHLEAQTLQTNRLHEEALTAISHIDAGNDQLIKAGKHNKTTRKWVLFFLIMASFVLLFLDWYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXR5</accession>
    <name>A0A9P6SXR5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Sphingomyelin phosphodiesterase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BGZ80_001433</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Converts sphingomyelin to ceramide.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="12">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the acid sphingomyelinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001325">
        <property type="protein sequence ID" value="KAG0010502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXR5"/>
    <dbReference type="OrthoDB" id="282973at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004767">
        <property type="term" value="F:sphingomyelin phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006685">
        <property type="term" value="P:sphingomyelin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00842">
        <property type="entry name" value="MPP_ASMase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045473">
        <property type="entry name" value="ASM_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041805">
        <property type="entry name" value="ASMase/PPN1_MPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011001">
        <property type="entry name" value="Saposin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008139">
        <property type="entry name" value="SaposinB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011160">
        <property type="entry name" value="Sphingomy_PDE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10340">
        <property type="entry name" value="SPHINGOMYELIN PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10340:SF34">
        <property type="entry name" value="SPHINGOMYELIN PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19272">
        <property type="entry name" value="ASMase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000948">
        <property type="entry name" value="Sphingomy_PDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00741">
        <property type="entry name" value="SapB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47862">
        <property type="entry name" value="Saposin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50015">
        <property type="entry name" value="SAP_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10 11" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 14" id="KW-0732">Signal</keyword>
    <keyword evidence="7 12" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040498978" description="Sphingomyelin phosphodiesterase" evidence="14">
        <location>
            <begin position="19"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="domain" description="Saposin B-type" evidence="15">
        <location>
            <begin position="43"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="376"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="411"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="413"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="13">
        <location>
            <begin position="47"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="13">
        <location>
            <begin position="76"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="13">
        <location>
            <begin position="175"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="13">
        <location>
            <begin position="181"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="13">
        <location>
            <begin position="334"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR000948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000948-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR000948-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0010502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="613" mass="66450" checksum="ECA73595BC4BA99E" modified="2023-09-13" version="1">MRFSTVILSLAAASAVYSAPVQNMSKRNWFTDDLKSLITKALTTLECGACEAALVGVKDVALLNKQWVLDAVNDLCPTLSKEPAAVCAGLVNSQGPVLINSLLSADLTGGDAKEICFQIGGICPAPAISSGTLTFPKTRPANPVVPTPSGVQVDVLHLSDWHVDEKYVAGSEAACGYPTCCRQYSDSSTTVNRSASSWGDYNCDTPVKLGQNLLSYIPTVAKPSFAILTGDVPPHDIWLESQSTVVPEESDAYTNMAGLGINIYPTVGNHEAGPPNLFPTTASGGDLSWLYSSLASDWSRWLPSDAVTSAKNYGAYTVSPTAGFRIISLNTNFCYTMNFYLYAHTSDYDPNGEINWLITQLQAAEDAGERVWIMGHVGPSQTDCLQNWSALYYQVVQRYSPHVIAEQFFGHTHYDEFALYYGPGSKTSQNALATAWIGPSVTPYTNLNPGFRVYKVDTKSWNVFDSQTYVANLDKAATWDSTGATPNWHLEYSARQAYGAYAPIADNLPLSASWWHNVTTAFQSNSAAFNEYWTYRGKSSNKIGACAAGSACSTEMICDLRAGQSSDSCTKISLSLKKRSDDNRSSKRADAKANLAALLKRESKPWAKKLCAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYN0</accession>
    <name>A0A9P6SYN0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_000189</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001032">
        <property type="protein sequence ID" value="KAG0012124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYN0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0012124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="148" mass="16588" checksum="AC0B93A3EDC9EE71" modified="2023-09-13" version="1">MGFVSLTLRIQLQRFGQNNSSNDVGRRGPIALSDDDLVGATGIEWEDIEAQLHGDNHGEDQEEEMDDMTSRPLKPMSRQDRYLYDDEDEEGEEMSSNVNVNRPYADDEGEDDGDVNHEGTNSEAALREGESTESQKDSLFKLEDADSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZ20</accession>
    <name>A0A9P6SZ20_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphoglycerate mutase family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_011401</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000911">
        <property type="protein sequence ID" value="KAG0012953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZ20"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051710">
        <property type="entry name" value="Phosphatase_SH3-domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16469">
        <property type="entry name" value="UBIQUITIN-ASSOCIATED AND SH3 DOMAIN-CONTAINING BA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16469:SF27">
        <property type="entry name" value="UBIQUITIN-ASSOCIATED AND SH3 DOMAIN-CONTAINING BA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0012953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="311" mass="35077" checksum="BE9E57AD50D79C3F" modified="2023-09-13" version="1">MQARQTGRMIRDFAQESRSLSTPASLDSVNKRIADKSGTPSAVSNEDEQQKDWTTLQRITPPESPGLGRFNPMSSQGPNKHGASTGDQKRQHHFAIVTSPFLRCSQTAIEIAIGMRTASAETSGSDGNCSKSTKWLSSEYVSGPVPDSIIVQRMQDFAMARRDHEQYYSIDWKYLAKDRQLPTWPETRESMQERLDRTLDHILKSYTSNDKSAERDLSIVFVTHASPVNALMEACLQFPTLVPVPNCSISRCQWTPLSTSNANEEDSSQQEPGMFDVLMQSTHTFTVAGEEGRWLLDYQTYTAHLDRDYRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZ51</accession>
    <name>A0A9P6SZ51_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">VPS9 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_011258</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0507 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000885">
        <property type="protein sequence ID" value="KAG0013153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005769">
        <property type="term" value="C:early endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030133">
        <property type="term" value="C:transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097422">
        <property type="term" value="C:tubular endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045022">
        <property type="term" value="P:early endosome to late endosome transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.80">
        <property type="entry name" value="VPS9 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051248">
        <property type="entry name" value="UPF0507/Ank_repeat_27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003123">
        <property type="entry name" value="VPS9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037191">
        <property type="entry name" value="VPS9_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24170">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24170:SF1">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G09870)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02204">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00167">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109993">
        <property type="entry name" value="VPS9 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51205">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VPS9" evidence="4">
        <location>
            <begin position="329"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="2">
        <location>
            <begin position="582"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="2">
        <location>
            <begin position="620"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="2">
        <location>
            <begin position="757"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="2">
        <location>
            <begin position="790"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="161"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="499"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="852"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1143"/>
            <end position="1191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1328"/>
            <end position="1354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1368"/>
            <end position="1423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="175"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="517"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="852"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="1151"/>
            <end position="1165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1175"/>
            <end position="1191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1372"/>
            <end position="1385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1400"/>
            <end position="1423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0013153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1423" mass="156190" checksum="B259A531574A10EB" modified="2023-09-13" version="1">MDLALSLFHTSGQEASERQSLTPSTTSNYFLSLLFFHESTSLSTSALISHEQLKNFQFLKKTFEAALAMIVREKNHHQLVILCPVQQSLMGIDGRSKLEWEWGGIDEEFISMLATLWDCVTTAKGFKLLKQARLVSERIFYDDEGRGWVIQFIDRPLVGASNEGDLSPRPRSPDSIGNDSSRSTASFSPPLRSDSPRFTKAARRSKYLSAQLHSPDPYNDTRRRTKSRPLLTLQIVLQKFPGTPQKLEQLVMDFNDSTMTKDNLDDIRTSVVRLLTNCVELLNQLDSSVLLALLDEYGATVDILDQLLENYIMNSTYDIVFFKITLKLKTQDWELAEATRELRKVLRLTPFQNLDLGQVGLPDTPQHYQCLVSALNEFQSIGVLRTPEEKLGCLVQSIKVSSALTGGADDLIPILLLTVLRSGISNLASNLYYMKNFVLFGDTTRGEYGYSLSTLEAVSRYILSQVKQLSPLSAKNQDYWEKVCAGDLEDVKAIYSNASEPSQSKPLQPQAVIRRPSTNSIDSSSDASINSSLQNPLSASPLLSRDAEGNNGVLLACKAQQVDMLRYLVDEQDCSIHVSNYEGKTPLMLAVDLENVDMVRLILRVLGSDEMGIINKQDVLGNSAVHLCASKGNLTILNELLKANSDLGLPNNEGDTPLIIAAKLSERSENHTKVISMLIPLMKVDGFNRQNNIGDTAFHFITDLALIADLATRGANPEIDNYAGWTPLLKWALHDNVAVVEGLLATGRVDALMTDSRGYTPLHMACLRGNLEMVQMLEPHTPIDYQSAIDGSTPLQLACQSSSVSVVEFLLQNGANPELRDWTNESPADMTNDSAILDLLDNAMLFWDSRGSFDQPTETKTPISVQTGPSAEDEKSPLYRSGKRVIRVVRGTMKQDGSVRYIVKSGSRDMIAERSSIKQESALDSIFDDFPPVVENLEHEETFFKHLNEEILNLDRAVQQARKHARKLSRCTQDVPQQLEILSSVLDKAHSINFEGKEAYVQAMKAIASTQTTMHTSDIESLGNLFEDFSFVIDGTLKAMKHPQEIISSIRQLRLVVSKTEQSMRRSDMLWSGLSSIGGGAMTAIGGAGAALGAVGHVATSTFEAVSGSIGQGGGGSGSRHIKAASESLVKGASVSVLEGGRATSPLLSPTVPPQRAPPSTPPPQVKDSLVVKLSPNSSTTSGQQRSRLSMDVTKTYSTSSLLSSPFSSIAAVASAATRQTPLDETKDKIVKASSLLNCLRSSLFEELAHLQNNHTKELERAMRDFGARQLQIEKSRLRDMVEILNDLRFESNGTTAAAAAGGSNIPGAASGPGSQLFTGSTFDLAQGRASRGVSRQSSMHALSPGIGSTSRDESGILFNFEADEKAEARNQQRQYELQHKNSTVRPKDLQRHLSQSNTSERESPSTHRKDEDSMSEKIPFDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZ98</accession>
    <name>A0A9P6SZ98_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cell wall protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_011079</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000847">
        <property type="protein sequence ID" value="KAG0013429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZ98"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040400646" description="Cell wall protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="198"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0013429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="230" mass="24632" checksum="723993C1610692AE" modified="2023-09-13" version="1">MKFDKTILLISIAIATVVSANPLEPASVGAAVTANPLSRRDDDPILHAIVKLTTGHYPDIANLGLDGLLGDMKAAKVTSGSEELPKERDLLNIAVKAKIDQAKKDCSRESLEPLARATIGAETDSDNKWADNEETKRKLLGLDAKLVKLIQDRIQVNINAELLSKECTEKMTNIEIAPAEESLNAESVESEPEANEKLATVAPTPAPEEALVPEPEAIEPACSRGSSPRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZF3</accession>
    <name>A0A9P6SZF3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Accessory factor associated with RNA polymerase II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">CDC73</name>
        <name evidence="9" type="ORF">BGZ80_011049</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CDC73 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000840">
        <property type="protein sequence ID" value="KAG0013484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZF3"/>
    <dbReference type="OrthoDB" id="2186602at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016593">
        <property type="term" value="C:Cdc73/Paf1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000993">
        <property type="term" value="F:RNA polymerase II complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032968">
        <property type="term" value="P:positive regulation of transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11990:FF:000002">
        <property type="entry name" value="protein CDC73 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11990">
        <property type="entry name" value="RNA polymerase II accessory factor, Cdc73 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007852">
        <property type="entry name" value="Cdc73/Parafibromin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031336">
        <property type="entry name" value="CDC73_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038103">
        <property type="entry name" value="CDC73_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032041">
        <property type="entry name" value="Cdc73_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12466">
        <property type="entry name" value="CDC73 DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12466:SF8">
        <property type="entry name" value="PARAFIBROMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05179">
        <property type="entry name" value="CDC73_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16050">
        <property type="entry name" value="CDC73_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Paf1 complex subunit Cdc73 N-terminal" evidence="8">
        <location>
            <begin position="5"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="Cell division control protein 73 C-terminal" evidence="7">
        <location>
            <begin position="249"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="124"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="199"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="126"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="199"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="220"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0013484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="413" mass="46364" checksum="EB73748465C7115A" modified="2023-09-13" version="1">MSKNDPLSLLREFTISKKPITLVNEGGNLVTELTDAANVVFADDKQTFQFPRSTPTNYRRGASDETYTLETLLFLLQRAHQSVAEYSLEGAQKGIPIVSILDKRGVLDYLTGVTATSTHIVYQSESNKRSGDSVVDDKQDDPSKKQKSAASVGHGDENEVLRLIISRERLARTTASVLRGNKSFANIQKIGASILLKSKSKEEKAPVKKPDSRQPGATLPSTTSSSRPGSAPGASTSRTSSSKSKSSSSRIPIIIVPAAMTSMLTMFNIKQFLEDQLFVESEGIRNKGGPKPTRLMIERRQKPNETHKISYHVIDSTDQMRDEDWDRVVCVFTNGAEWQFKKWKWQKPVELFAHVKGFYVKWADEQPKEIIKSWNVEVLNLNRHRRHADTAVVTEFWDKLQGWCLANKPHLAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZM2</accession>
    <name>A0A9P6SZM2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">GAD8</name>
        <name evidence="14" type="ORF">BGZ80_010612</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JAAAID010000758">
        <property type="protein sequence ID" value="KAG0014149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZM2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11651">
        <property type="entry name" value="YPK1_N_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000008">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000048">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017892">
        <property type="entry name" value="Pkinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24351">
        <property type="entry name" value="RIBOSOMAL PROTEIN S6 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00433">
        <property type="entry name" value="Pkinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="219"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="13">
        <location>
            <begin position="475"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="552"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="15"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="77"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="565"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="252"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0014149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="576" mass="64046" checksum="7BB2AF4536223DE3" modified="2023-09-13" version="1">MSWLHSKTTRPQGNGHSQTPSSSSSHSTTPPASGHSPSPSGQSQQNGAAKTGLLIIRVVEARGLTLPPGSTNPPFVPKQQPNPVNSNRESLQRKWWLPYAVLEFDKNEVLIDALGGELSNPVWQYRAHFDVSRVSDVQLSLYIRIPNPKALAALDKSGGMMESENSSEDVFLGNVKLEPRWDEQMQDEWFTLQGGTGKVRVQVAFKRDSANTPLTIDAFDLLKVIGKGSFGKVMQVRKRDTSRIYAMKIIRKAHIISRSEVNHTLAERTVLAQINNPFIVPLKFSFQSPEKLYLVLAFVNGGELFHHLQREGRFSEERSRFYAAELMCALECLHGFNVVYRDLKPENILLDYTGHIALCDFGLCKLGMTETETTNTFCGTPEYLAPELLLGQGYTKTVDWWTLGVLLYEMLTGLPPFYDENIHEMYRKILQDELRFPDEVAPDARALLSALLTRDPTQRLGNNGSSAIKQHPFFKPISFPLLMAKQIQPPFKPSVSSAIDTSNFDEEFTSEEPLDSVVESSFLSETVQLQFKGFTYNPANDGVLGASMANQSALGSSGERPLHGRAGGMGQGRSGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZV0</accession>
    <name>A0A9P6SZV0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Palmitoyltransferase</fullName>
            <ecNumber evidence="11">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">ZDHHC14</name>
        <name evidence="14" type="ORF">BGZ80_010654</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="11">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="11"/>
    <dbReference type="EMBL" id="JAAAID010000765">
        <property type="protein sequence ID" value="KAG0014093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZV0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006612">
        <property type="term" value="P:protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22883:SF43">
        <property type="entry name" value="PALMITOYLTRANSFERASE APP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22883">
        <property type="entry name" value="ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0564">Palmitate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="385"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="437"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="13">
        <location>
            <begin position="339"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="158"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="230"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="166"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="203"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0014093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="497" mass="54875" checksum="581728A69F2F2BD4" modified="2023-09-13" version="1">MPEGVDTAVLGSGTKTVLEPESAPFQSFQSFFSPQQSTHVGFEQMSMDNHPLSSTTGNIQSTVNDSRANLLISPRPRYTTRSFRGPNSEALSMGAIIDANHSASSLNRGIGSPDNNPSALGTISSIVNRTPEANSEEMEKERLDYQIKGRSHVSIGYSGGLDSDRWTTTTAKGNQHSLGMESIPDDRSSRVTGRHSISKPKMSTSPAATNSSAAISGSSEMLPLSEFLSQTADSDKPDTPSTEGLSRRTDDTELNYPMSPYLWHRLSPAAPVVQAYVFIVAFSSMLKTSWTDPGVIPRGIDGDPPVDPPIERDPSTASYYPPQGQPRLKEVQIGVYTVRLKYCDTCKIYRPPRCSHCRQCDNCVEDEDHHCIWLNNCIGRRNYRYFLIFVTTMSIYAFFTFALCLTQLLLLYHDKRNSAVNPESVSFSKDAMAKAPVAVLVMLYSVIMGLAVGSLAGYHFWLATKNRTTHEQAANPKLYPEERLHGCIMHVKQHTDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZW1</accession>
    <name>A0A9P6SZW1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_010239</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000693">
        <property type="protein sequence ID" value="KAG0014765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZW1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0014765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="308" mass="35049" checksum="C2B60451B4F6F3FC" modified="2023-09-13" version="1">MATINDDVILAVLACCDVVTVAKCRSISKRFKHIIDEELALDNADFSTLTFRQRRNIKDSVMTPKFTHIFRRASYVNLNGTGIGHYGAMKLVTDYTKELHVERCPRVDIERLIQAIAGDRWLSYDLDPVCLYVKSRETRGSYNYLTVIKPLSDYNWAVVMMSNDCPCQYVKIEEYQEPELNVAFCHACNKAVEEYTFKLTCNRCGFVTCKECQAVACVTPSCAVFCKGCVTEVKCSLCHNEWCMWCRNVWVFQCYGCEANVCGECQPSHLKCSKGQYHEYCSQCAGAMADKHGHWCCDAGEFSIEPTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T040</accession>
    <name>A0A9P6T040_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_009938</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000641">
        <property type="protein sequence ID" value="KAG0015299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13275:SF4">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 72 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13275">
        <property type="entry name" value="YL-1 PROTEIN TRANSCRIPTION FACTOR-LIKE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="332"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="401"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="827"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="889"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="961"/>
            <end position="993"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1029"/>
            <end position="1055"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1097"/>
            <end position="1330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="128"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="352"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="416"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="469"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="483"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="827"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="853"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="894"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="918"/>
            <end position="943"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="965"/>
            <end position="988"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1032"/>
            <end position="1055"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1114"/>
            <end position="1125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1138"/>
            <end position="1155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1156"/>
            <end position="1178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1194"/>
            <end position="1203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1226"/>
            <end position="1243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1283"/>
            <end position="1299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1309"/>
            <end position="1320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0015299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1330" mass="146193" checksum="A294E48A7D08085E" modified="2023-09-13" version="1">MQPSQKTNAPKLVFGSSLDYQERRKRLRLLPPSPPVGLNPFHAPTVNALEGMFERVMAIANASNKPSSSSSSKWHPNSQHRFLVDHNKPEERDTIASWPADPLVISSVKKSSHTHKGCERPQMPSVWSTLSEPTSSTEPSQNGYRYMLPPSNVSSAMEAAQKPQEHPSVFAQPPQKWASVHQEFTESTTQPPRVASTNVPEITRPLKRDRSPAPADDGAESEASVVELLSSDDENISEVSEVEEEEEEEEEDDGIEEIAIQEEYEEYEEYEDEYDQAEEDALEDERKELHPGFAVEHEDFKNYRPQMDRGYQQLTGVMTLDDSEDEQTAYDNLQDYNEAEAESGEQSQSWRRTTDSMRSHGFDTNIQQPAEAEPGEQIHLWHRSMDSTRLQGFDTNIQQPFNYGVSELDHSQEDGYSVEEDVEEGYSEGDVGEEQEQPQTYASDTETRAFTPASESSQIDREKSPSHASSELPSDDVVLLLDSDNEEPEENELLSNDGQDEIEDEEWAEEEEEEEEEEDDDDEEEEEEEEEENADEGAHHLQDEDEGRNGVVGLDSDHLESRLEREALVAEEKYNENEDFIEGDMQDSIDQAAAFSPLVLSDSAQGLGGSEIMESVEILEHESTPVLAAEEPATDEVVVTLDTLDNTSVDVEVDIIMSDNLAQASGDGQQRDHQTIFEDVHSITDILGDNEMAAVDEQVFSTTYPLVNMDVADPTEQYIARAMPSATQNKDSSTSSMDLEPASTAFDLQVISELSETQVENEPIPQTLREQAFSADFNPEHVSLLERLRAVAQEEKIALVTRDLSPDMDLDKFPILLRRATSVQPITAPDDQNTVQSTSPTKVLDPTTAADNSTSSGTELSSSAPRKARLSRTSTIAQTVRDGKAFIEKIEARSSPNSKSSQSLRSSSNITDAMDDIPSSPTLSVVSVPESNTESVSTTNSSSTRHRSEVRLLVEEARAFCSGIPGPSRTGSNSSSTSAPPAQPVSSPAHRPLTVDTVAPLPAKAQSVGSSPSRGAGYVRRRISFGEGNDPSLISGSEQQALASPASSINSPTASRTRGIGVVDLAAENVIQSTVVGNHALRLFINSTSPVISTGFQTESQANDQEPPAASPGVHSQAQAQTQAHPVTPAFTFGQMPSGITGSGSTRSNSNTNTSVGFSFGTSFVTTPRETSRESSVSPRKGTPFVIEPGIPSSAKSLNPQKNPQDRETIEIAIKSFKKDDKPEGGDEEEEEDHERDDEDEHEDEHHQADSDNDADNDIDNPSLHLVPTQESQDSPITIMVRAPKKKKTPSKTKRKNVKRREATRLQKQRNSNSDKSNAETFADEPSSLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T047</accession>
    <name>A0A9P6T047_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 16">Glutathione reductase</fullName>
            <ecNumber evidence="3 16">1.8.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">GLR1</name>
        <name evidence="19" type="ORF">BGZ80_010269</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11 16">Catalyzes the reduction of glutathione disulfide (GSSG) to reduced glutathione (GSH). Constitutes the major mechanism to maintain a high GSH:GSSG ratio in the cytosol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 16">
            <text>2 glutathione + NADP(+) = glutathione disulfide + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11740"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58297"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.8.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="13">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="16">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 15">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.7" evidence="3 16"/>
    <dbReference type="EMBL" id="JAAAID010000699">
        <property type="protein sequence ID" value="KAG0014706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T047"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004362">
        <property type="term" value="F:glutathione-disulfide reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.390.30:FF:000003">
        <property type="entry name" value="Glutathione reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000235">
        <property type="entry name" value="Glutathione reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006322">
        <property type="entry name" value="Glutathione_Rdtase_euk/bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046952">
        <property type="entry name" value="GSHR/TRXR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012999">
        <property type="entry name" value="Pyr_OxRdtase_I_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01421">
        <property type="entry name" value="gluta_reduc_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004776">
        <property type="entry name" value="PRK06116.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42737">
        <property type="entry name" value="GLUTATHIONE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42737:SF2">
        <property type="entry name" value="GLUTATHIONE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="FAD/NAD-linked reductases, dimerisation (C-terminal) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00076">
        <property type="entry name" value="PYRIDINE_REDOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="16" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6 13 15" id="KW-0274">FAD</keyword>
    <keyword evidence="5 15" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="13" id="KW-0520">NAD</keyword>
    <keyword evidence="16" id="KW-0521">NADP</keyword>
    <keyword evidence="13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9 15" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="18">
        <location>
            <begin position="8"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="Pyridine nucleotide-disulphide oxidoreductase dimerisation" evidence="17">
        <location>
            <begin position="349"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="12">
        <location>
            <position position="449"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="179"/>
            <end position="186"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="270"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="311"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="14">
        <location>
            <begin position="46"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00056905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU003691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU365016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAG0014706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="467" mass="50087" checksum="841C44E593388978" modified="2023-09-13" version="1">MPPTGKIYDYLVIGGGSGGNYLSPALLESPGAVGLIEGSGRLGGTCVNVGCVPKKVMWNTASIADAIRDAKEYGFPEAGSTKFDWLALKNKRDAYIKRLNGIYERNLEKDSVEYITGMASFVSKNSVTLGNGDEIHAKKILIAVGGRPTIPKVPGAELGIDSDGFFDLEHQPKRVAVVGTGYIGIELAGIFHALGSKVTIFSRTQEILRPFDHIIKDTLRKEMLNVGVEIVTKSQVKALAKSEGNAINLSYVSDGKEGVAEYDTVLWAVGREPLLEKLAVDKAGVTLNEKGYIAVNDYQETAVPDVYALGDVCGIEQLTPVAIAAGRRLSDRLFGPEQFKNSKLDYRNVPSVIFAHPTAGAVGLTEEQAKKEYGAENLNVYVSEFSGLYNAMKTHKTPSAFKLICAGPEEKVVGIHIVGAGSDEMLQGFAVAVKMGATKEDFDSTVALHPTSAEELVTLTKGNLKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0B3</accession>
    <name>A0A9P6T0B3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Homeobox domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_009707</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000605">
        <property type="protein sequence ID" value="KAG0015687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0B3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008422">
        <property type="entry name" value="KN_HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050224">
        <property type="entry name" value="TALE_homeobox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11850">
        <property type="entry name" value="HOMEOBOX PROTEIN TRANSCRIPTION FACTORS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05920">
        <property type="entry name" value="Homeobox_KN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 4" id="KW-0371">Homeobox</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="6">
        <location>
            <begin position="116"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="4">
        <location>
            <begin position="118"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="67"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="211"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="67"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="106"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="217"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="241"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0015687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="259" mass="27342" checksum="B19F986916159205" modified="2023-09-13" version="1">MRTRSGISTNISIINTSINIRIDEIHSLQTNTNGPHITLHLLNFDSLPRPVPVKPAAFAAPSAVSSSAAVSSSSGPSTSGPSDNTISTTTSATAPATATATATTETNDKSDTHGTDPNRKRRGNLPKTVTSVLKSWLVQNAIHPYPTEDEKMRLSEATQLSMNQISNWFINARRRILQPILVEAAAAAVAGTDAPMDNVLIVRKGKGSRMQVEMECGGSSTQGQNQGQDQDQGQGQGQGQGQSQDQSQSQESGAKEPPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0H2</accession>
    <name>A0A9P6T0H2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">microtubule-severing ATPase</fullName>
            <ecNumber evidence="8">5.6.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BGZ80_009792</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>n ATP + n H2O + a microtubule = n ADP + n phosphate + (n+1) alpha/beta tubulin heterodimers.</text>
            <dbReference type="EC" id="5.6.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.1.1" evidence="8"/>
    <dbReference type="EMBL" id="JAAAID010000618">
        <property type="protein sequence ID" value="KAG0015541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0H2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008568">
        <property type="term" value="F:microtubule severing ATPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000022">
        <property type="entry name" value="Fidgetin like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000093">
        <property type="entry name" value="Fidgetin-like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.80">
        <property type="entry name" value="Phosphotransferase system, lactose/cellobiose-type IIA subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036181">
        <property type="entry name" value="MIT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050304">
        <property type="entry name" value="MT-severing_AAA_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015415">
        <property type="entry name" value="Spast_Vps4_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23074">
        <property type="entry name" value="AAA DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23074:SF86">
        <property type="entry name" value="SPASTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09336">
        <property type="entry name" value="Vps4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116846">
        <property type="entry name" value="MIT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0493">Microtubule</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="66"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="12">
        <location>
            <begin position="442"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="99"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="251"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="309"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="115"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="129"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="260"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="309"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="368"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00036378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0015541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="684" mass="74500" checksum="4A251DAE17458F06" modified="2023-09-13" version="1">MHTHPEHVTVPESLLSWINKALLPFLPKEKTSKPAVKAIAPPVIQYIPSWKAIVFRINKATTVEQLFIAILVFSLILLLISQCYRKLFKKSVLPRTTSKKTRKAALVPTRKTKGQMSSQQTTNATTSSPGRVSTRTSQSPSPLELQKIKHDQAYHLIDLGITHDTNGNLKEAIEMYKKGIETLKEALNVRYTTEAEFRESEVLGPKLRQNLQATESRLKVLQQKMAGRSLYSSIFSSVSSAVQAVSLAMSTGDGNSSAVTPPTTGSNYTTTQYPSMPAPQRRAARTTSGYSGNDEPVFNVVTVSKPVAVSSSRRTNPNSGSIGQSPSNSYGTGTRSTSHGSPRGTAATTRPGMITGGRRKPVGGSGGAPTTNGQSSETKNKISRLKNVDSKLANMILNEVLVDGATITWDDIAGLSFAKQALKEIVILPALRPELFTGLRAPAKGVLLFGPPGTGKTMLAKAVAQESKATFFSISASSLTSKFVGESEKLVRALFAVAREVQPSVIFIDEIDSILTERSENEHEASRRLKTEFLLQFDGAGSNSDDRVLVMGATNRPQELDEAARRRFVKRIYIPLPEHDTRQALLTKLLSGQSYDISMSEMQRLVKKTEGYSGSDLTALAKDAALGPLRSLGETLLDTPADQVRPIQYQDFEQALHTIRPSVSPQSLHAYEEWNREYGAGVRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0I7</accession>
    <name>A0A9P6T0I7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nitrilase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">NIT1</name>
        <name evidence="3" type="ORF">BGZ80_009583</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000588">
        <property type="protein sequence ID" value="KAG0015855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0I7"/>
    <dbReference type="OrthoDB" id="10250282at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07572">
        <property type="entry name" value="nit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045254">
        <property type="entry name" value="Nit1/2_C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001110">
        <property type="entry name" value="UPF0012_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23088:SF27">
        <property type="entry name" value="DEAMINATED GLUTATHIONE AMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23088">
        <property type="entry name" value="NITRILASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01227">
        <property type="entry name" value="UPF0012"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="2">
        <location>
            <begin position="4"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0015855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="276" mass="30065" checksum="6C1671F5EF91DB94" modified="2023-09-13" version="1">MQQVKIAVAQFCAGQSISANLATCIQLMGHASNALAKMIFLPEASDFIGNPSEEALTLAHPLNSGPFLQGICAEARRLGIWCAVGVHEQSPFPGKLFNTHVVINDQGSIVESYRKIHLFDVDIPNGPRLMESQNTVAGDKLVAPVSTPVGKVGLGICYDLRFPELALGLRRQGAEILTFPSAFTVKTGEAHWEVLLRSRAIETQSYVVAAAQVGKHSEKRSSYGHAMIVDPWGQVIAECDGKTEGFAVIPINLSSLERIRTEIPVMSHRRYDIFTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T125</accession>
    <name>A0A9P6T125_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Kelch repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_009479</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000572">
        <property type="protein sequence ID" value="KAG0016029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T125"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040118146" description="Kelch repeat protein" evidence="1">
        <location>
            <begin position="30"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0016029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="236" mass="25536" checksum="AF137C95523A7983" modified="2023-09-13" version="1" fragment="single">MLPQRHSIPGPTTFISIALILTSATLSTSTPVPVTVSGPAFARTATRLYISGGLTGTSANPILYSQFFSLDLTTPWNVSNPAWKQLHDGPRQNIFPAVFSADQKTMITFHSGTIFAERYSVDQDTWTPSQLVVNGGGNQGINAVTDPNTGLVYLAGGYSDPYRQSMDTYSFVNDALVQAALPAATTALPNRAYYTNIWTSKRNSILYFGGYNSTLGQISSNSITEFVPSTNTWNTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T146</accession>
    <name>A0A9P6T146_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Aminotransferase class I/classII large domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_008803</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000490">
        <property type="protein sequence ID" value="KAG0016910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T146"/>
    <dbReference type="OrthoDB" id="691673at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047536">
        <property type="term" value="F:2-aminoadipate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008793">
        <property type="term" value="F:aromatic-amino-acid transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009074">
        <property type="term" value="P:aromatic amino acid family catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019878">
        <property type="term" value="P:lysine biosynthetic process via aminoadipic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006571">
        <property type="term" value="P:tyrosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050859">
        <property type="entry name" value="Class-I_PLP-dep_aminotransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42790">
        <property type="entry name" value="AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42790:SF21">
        <property type="entry name" value="AROMATIC_AMINOADIPATE AMINOTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="6">
        <location>
            <begin position="121"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0016910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="477" mass="53166" checksum="B82D4AF73E29A62D" modified="2023-09-13" version="1">MSIAGPSQLPMAKDFSSFLSLEGASRKKSPLKGLLRFMKGDMVSLGGGLPHPSNFPFYSLSSDIASMKPVGQNVKNVAVVNEKAASVSSENVFVPHGPQPGKVENLSSALQMHRPKYQDWDVVLSAGNTDGFAKAVSMLCNRGDQILVEEWTYPAALEMMDPLGIRHVPVGMDGEGMSAVALKDLLDNWGSIPEQANEAKPRVVYLIPTGQNPTGATMSVQRRKDIIKVAKEHDLILIEDDPYYYLQFFIGEDKSADNETQSGWMPTLLSLDTDGRVIRLDTFSKTLAPGCRVGYMSMNARFCTIVQSHNEVTIQQPSGFSQGLLAEMLVSNWGQEGYKRYLTEKVRTEYFNRSQHLQACFRKHVNPRFASFIEPTAGMFVWIKIHVDQHPRYGTMPDSALMLELFNKCVENNVLMVPGWQFSCKPKPSNLDLSDLLGCWFDDEATYLRATFSYATFEQMDQAMTRFGESLEAVFSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2B3</accession>
    <name>A0A9P6T2B3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">60S acidic ribosomal protein P0</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">RPP0</name>
        <name evidence="8" type="ORF">BGZ80_005393</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. uL10 forms part of the P stalk that participates in recruiting G proteins to the ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uL10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000266">
        <property type="protein sequence ID" value="KAG0019705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2B3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05795">
        <property type="entry name" value="Ribosomal_P0_L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1730:FF:000002">
        <property type="entry name" value="60S acidic ribosomal protein P0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.105.20:FF:000001">
        <property type="entry name" value="60S acidic ribosomal protein P0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.105.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050323">
        <property type="entry name" value="Ribosomal_protein_uL10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001790">
        <property type="entry name" value="Ribosomal_uL10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040637">
        <property type="entry name" value="Ribosomal_uL10-like_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043164">
        <property type="entry name" value="Ribosomal_uL10-like_insert_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043141">
        <property type="entry name" value="Ribosomal_uL10-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030670">
        <property type="entry name" value="uL10_eukaryotes"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45699">
        <property type="entry name" value="60S ACIDIC RIBOSOMAL PROTEIN P0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45699:SF3">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00428">
        <property type="entry name" value="Ribosomal_60s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00466">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17777">
        <property type="entry name" value="RL10P_insert"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039087">
        <property type="entry name" value="L10E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160369">
        <property type="entry name" value="Ribosomal protein L10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 8" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL10-like insertion" evidence="7">
        <location>
            <begin position="108"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="272"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR039087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0019705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="292" mass="31699" checksum="E853C09E318D9F20" modified="2023-09-13" version="1">MSKAGKKEEYFQKLKAYLEEYPSIFIVNVDNVGSNQMHQIRKALRGDAKILMGKNTMVRRAIRILQAENPNYEKLMPAVRGNIGFVFTSADLKTIRDKILSNRVKAPAKAGALAPIDVFVPAGNTGMEPGKTSFFQALGVPTKIARGTIEIINEVHLIKTGVRVGASEAALLNMLNISPFTYGLTVVQVYDNGTVFHPSILDIEEETLIGYPTIASVPHSIINAYKNLLAVSIATEYTFPGSEKVKAYLADPSAFAVAAPVAAANTTAAAKVEEKVEEKEESDDDMGFGLFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T323</accession>
    <name>A0A9P6T323_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PCI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_004501</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000229">
        <property type="protein sequence ID" value="KAG0020264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T323"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045107">
        <property type="entry name" value="SAC3/GANP/THP3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005062">
        <property type="entry name" value="SAC3/GANP/THP3_conserved"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12436">
        <property type="entry name" value="80 KDA MCM3-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12436:SF4">
        <property type="entry name" value="LEUKOCYTE RECEPTOR CLUSTER MEMBER 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03399">
        <property type="entry name" value="SAC3_GANP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040154215" description="PCI domain-containing protein" evidence="2">
        <location>
            <begin position="17"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="domain" description="PCI" evidence="3">
        <location>
            <begin position="586"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="364"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="438"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="90"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="216"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="313"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="697"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0020264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="697" mass="77922" checksum="65C0FC3BC2CE6FDF" modified="2023-09-13" version="1" fragment="single">MTLGAALSSVITFNLATPTTPASSADQAAALYAEQYQQYAQQYQAWAAANPGYQHPQAPPGVAPGASTATGAIDYSAYYQQYQQPPPPATQQSGQPPQQQQQPGQPSQQQQQQQQQELTPEQYAQQYAAYYAQYYQTQAAPGSVPPSTGAATPATAPAGAAPYSQAQYQDYYAQQAQASQPYSYPSSAPGTQAPAYNYAAYQTPGQPAQPAPLTPYPYTYQQPQSQQQSYSSSSYSSNPPNSSYHQSYPAQSGPSHSSYSSGQYGKFTSRPHSQQGQSKAPFDYQAFQKQKHLEAKQRYQESELKVSGESDKNQAQLQKRLSETNLSDDGYSTSDANMAKTKLEKPAYLSVKSKKVKPLMTNVLESKDPEPSPSSPAPAPSREAWPESLKEYVVRYFNTVAEEDQEAAQEDLKSMVARYHGQGKLWEIDWDNMQIPSRKMSVSPEPETLGSEERAKREKRMRRFEEEAMANKPPSKKATRMVYAQPVNNGDVIDWDRHTIVGTNTNLEKHYLRLTSAPDPSTVRPLHVLRETLDLLKRKWSNHENYAYICDQLKSVRQDLTVQRIKNDFTVAVYEIHARIALEKGDLGEYNQCQTQLKALYELKLPGSVMEFTAYRILYLLHTRNPSDIIAMLRSLTPAQKEDPSVRHALKVRTALASSNYQALFKLYLDAPNMGPFLMDQFVDRERVQAMARICAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3S2</accession>
    <name>A0A9P6T3S2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Arrestin C-terminal-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_000178</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000103">
        <property type="protein sequence ID" value="KAG0022476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3S2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011022">
        <property type="entry name" value="Arrestin_C-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02752">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin C-terminal-like" evidence="2">
        <location>
            <begin position="119"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="332"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="385"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="505"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="333"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="385"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="399"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="533"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="580"/>
            <end position="590"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0022476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="597" mass="64941" checksum="1E2BF8C1CDAC6BC7" modified="2023-09-13" version="1">MKKLAIVLVEDTHQETKPDTVEYMPGDTIAGNLNEYQYAPWTDVRNEIPKNYRHGIVKYTLFATISSKTFLGGMQEVKANYVVQVKDLVNCMIQPYSEPVSVNGSSNTKPDSDKPKNLASATVQLARSAYLKGQSLHLSINMAHPRSIQRDPGCWIQLLRKESYNAGKEVKEYSHVVASATYAVNIDSGTNTGTILADLTIPDKAIPSMTTTKIVSIQYYIVILFDMRPRTGFMERRSRRTVNKKLRSKLLDAPGGFEVEIPIVIGTVSDIHHQHRRSPFSRDVASITTAASNLSISDASNTMASPLSLSPTSSHDTHTGYATLPVAYGRQASEPSYRSLTSTTNDFANRSRTLPSHQSSPATNLTYSKPLPSLPSMFINTSPDYVGSSSAHPSQPIHSISGPSMPLMSSSSSSSSSSPHSTYSSVPPLSRPVPNPSDGTSMYGPNGYPREKVPDPVQRHINIQPPLSFHLPSPTAPQAVDLGLGPSSPGVYNHRFSLIMATQGSSNVDGESTAGYFQYQPPQPPRSGAASGSEHNPLQLQQQTSFIPESSASSRDPQQSTLSSSDDIEHERHSAPAYTQIAQSSGTEPYTTDHNKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T4J4</accession>
    <name>A0A9P6T4J4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Low-affinity phosphate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">PHO91_2</name>
        <name evidence="9" type="ORF">BGZ80_004778</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000024">
        <property type="protein sequence ID" value="KAG0024264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T4J4"/>
    <dbReference type="OrthoDB" id="10260443at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006797">
        <property type="term" value="P:polyphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01115">
        <property type="entry name" value="SLC13_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004680">
        <property type="entry name" value="Cit_transptr-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10283:SF92">
        <property type="entry name" value="LOW-AFFINITY PHOSPHATE TRANSPORTER PHO91"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10283">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 13 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03600">
        <property type="entry name" value="CitMHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03105">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="491"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="526"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="571"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="616"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="657"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="700"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="742"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="773"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="798"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="836"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="881"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="930"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="domain" description="SPX" evidence="8">
        <location>
            <begin position="2"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="140"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="200"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="140"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="207"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="286"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0024264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="953" mass="105205" checksum="FF3DC3A624F40ECA" modified="2023-09-13" version="1">MVKFSHSLQFNTVPDWANEYIAYSILKKTLYTIEKYNVQHNLEGKPTDLEQGFDAKFSVPSSSEKPSKIKRLLWRRSKDSKDVESTGSVDTALHDGSDIFPPESEAFERGLAKELSKITSFYIRKERELSTELDAVDRQWQQEEQRQKEERLARGGSEEDTEVNDDINRRRLSMNTDEEKQLAAAEKTQLQEMMSWDKDGLTDQDAKSTGPTANDSTVGGSAAGRGKAVAGSDSVGDNDTHADGKSSNGDPTEIVWRRECLIESGDDEKSTKKKSKSSLPISRSQSTDDLRVPLDDSTEIKRTQSHHQLRKPSINPKRTLGHASGRENPNQKPSLYAPLTTEALLRRRIIDTYVYFSELKSYVALNYLGFKKIVKKHDKLAGCSTLDNYMATVVDLSVPFQAETRQNLDQQIIRLQALYARSCTNGSMALAAKELRSHLREYIVWERNTVWRDMVGQERKAEGARAVKEHEPWMVFGKEISFISKEDGRRIILGILGIIIFAVLMNVTIFDTREQNRCFAILITTAYFWATEVFPLFATALLVPLLTVLCQVMRDPTTKATLSTSAATKLVFGYMFSPTIMLLLGGFTIASALSKYGIAKAIASAVLSKAGTDPKWVLLANMFVATVASMFISNVAAPVLCFSLIQSILRTLPHKSSFAPCLIMGIALASNVGGLASPISSPQNIITIQYMNPAPSWGNWFAVSIPLAIIIDLIIWAWLMILWRPQRDTPSIPVVHATKERITWTQAFISLVTIGTIVLWCMENTLEAQLGDMGIIAILPLIAFFGSGLLNKDDFNNFLWTVIMLAMGGIALGKAVDSSGLLDTIAHHIQSAVADMSVWVVLVIFGCLTLVFATFVSHTVAAVIILPIVQQVGLSFPNPHPNILVMGTGLICSCAMGLPVSGFPNMNAIAMEDEMGKPFLRTIDFLKSGVPLSILATLCVVSVGYGIMSALGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T4U0</accession>
    <name>A0A9P6T4U0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Eukaryotic translation initiation factor 4E type 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">EIF4E3</name>
        <name evidence="7" type="ORF">BGZ80_000897</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the eukaryotic initiation factor 4E family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000012">
        <property type="protein sequence ID" value="KAG0024596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T4U0"/>
    <dbReference type="OrthoDB" id="17977at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016281">
        <property type="term" value="C:eukaryotic translation initiation factor 4F complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000340">
        <property type="term" value="F:RNA 7-methylguanosine cap binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.760.10">
        <property type="entry name" value="RNA Cap, Translation Initiation Factor Eif4e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023398">
        <property type="entry name" value="TIF_eIF4e-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001040">
        <property type="entry name" value="TIF_eIF_4E"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11960">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11960:SF66">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TYPE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01652">
        <property type="entry name" value="IF4E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55418">
        <property type="entry name" value="eIF4e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5 7" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0810">Translation regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0024596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="218" mass="24204" checksum="CE1F484B34837618" modified="2023-09-13" version="1">MPSSIAFQQGGVGAMAPASPRGADNGEAKGPSGSESGVSAVAAVPIPLRNEWVFWHDKFVANATPAEYTENLREIADVNTVQSFWSVYNNITGPERLTLRCSLHFIHKGVKPLWEDPKNEHGGAWNFRTAKGDTAFVWRELLMALIGEQFEDTIAKGDQIFGLSVSARWNSDIFQIWNMDSSLKENATVMDKVAEILKGVQIQAPFYKAHKDHDHFKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MCU7</accession>
    <name>A0A9P6MCU7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_008557</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004677">
        <property type="protein sequence ID" value="KAF9992421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MCU7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9992421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="92" mass="10417" checksum="E4854D42E5D4FA92" modified="2023-09-13" version="1" fragment="single">RLGQRIEKTVAIRPNDDEKLCPVAAYSCYLTRIADYPLVIPHPKDGSIKYAPLLRNSRHLNKPLSAETISNQMDTISCKIPELERATRCIKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MD79</accession>
    <name>A0A9P6MD79_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glutathione synthetase ATP-binding domain-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ACL2</name>
        <name evidence="1" type="ORF">BGZ80_008178</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004364">
        <property type="protein sequence ID" value="KAF9993336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MD79"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9993336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="121" mass="13598" checksum="1A2B11F56ECA88C5" modified="2023-09-13" version="1" fragment="single">MSAKAVREYDGKLLLAHWLHRAPIPATDAGSGSKFIQPATRLAHISIDTGLLRLDKAQFDQHVRSTLDQLEVSHPWLLTQKLVAKPDQLIKRRGKSGLLLLNADWAEARVWIENHAAKEVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MDS2</accession>
    <name>A0A9P6MDS2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Elongation factor 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">EFT1_2</name>
        <name evidence="8" type="ORF">BGZ80_008159</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004343">
        <property type="protein sequence ID" value="KAF9993400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MDS2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01681">
        <property type="entry name" value="aeEF2_snRNP_like_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04096">
        <property type="entry name" value="eEF2_snRNP_like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16261">
        <property type="entry name" value="EF2_snRNP_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000006">
        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.870:FF:000002">
        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.870">
        <property type="entry name" value="Elongation Factor G (Translational Gtpase), domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005517">
        <property type="entry name" value="Transl_elong_EFG/EF2_IV"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908:SF10">
        <property type="entry name" value="EUKARYOTIC TRANSLATION ELONGATION FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908">
        <property type="entry name" value="TRANSLATION ELONGATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03764">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00889">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Translation elongation factor EFG/EF2" evidence="7">
        <location>
            <begin position="108"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="Elongation factor EFG" evidence="6">
        <location>
            <begin position="222"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9993400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="296" mass="32197" checksum="09B00109695EFD6A" modified="2023-09-13" version="1" fragment="single">VAVECKSAADLPKLVEGLKRLSKSDPCVLCFTSDSGEHIVAGSGELHLEICLKDLEEDHAQVPLRKSDPVVQYKETIQAESSVTALAKSPNKHNRIFMKAAPLGEELALAIENGKIGASDEFEWDNQEARKIWCFGPDANGANLMVDLTKGVAYLNEIKDSCVAAFQWATREGVFAEENMRGCRFNILDVVLHADAIHRGGGQIIPACRSAIYAAAYVAQPGLMEPVYLVEITCPEQAMGGIYGVLNKRRGHTIGEEQRPGTPMYLVKAHLPIAESFGFTADLRQATGGQAFPWTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MEV1</accession>
    <name>A0A9P6MEV1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Amino acid adenylation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_007620</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003932">
        <property type="protein sequence ID" value="KAF9995051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MEV1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043041">
        <property type="term" value="P:amino acid activation for nonribosomal peptide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05930">
        <property type="entry name" value="A_NRPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.30:FF:000010">
        <property type="entry name" value="Enterobactin synthetase component F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.980:FF:000001">
        <property type="entry name" value="Non-ribosomal peptide synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.38.10:FF:000001">
        <property type="entry name" value="Non-ribosomal peptide synthetase PvdI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.980">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.38.10">
        <property type="entry name" value="Luciferase, Domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020459">
        <property type="entry name" value="AMP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF1">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00154">
        <property type="entry name" value="AMPBINDING"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="3">
        <location>
            <begin position="1"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="4">
        <location>
            <begin position="386"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAF9995051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="493" mass="53976" checksum="96E91D3F03398ED6" modified="2023-09-13" version="1" fragment="single">MSYGELNVRANGLAHSLIGLGVKPDSLVAICVDRSLPMVIGILAILKAGGAYVPLDPSFASERLHDILIDASPSILVADGAGIAALGPSISESIVVIDPNVMLEMPTENPHVPELTTEHLAYVIYTSGSTGKPKGVMIEHQGVTNLVMSRPSVFGVGPSSRILQFFSFSFDGSVHDIWSALCFGGSLHVLPDHARQDRSQLWSYLEEHAITHVLIAPAVLQDCKDLTPLSTKLNITLGGEALSSDLLMSLRRLVPYGSIANDYGPTETTVDAILWKCPDNFDGEIIPIGRPHPNKRAYVLDSYRRLIPMGVTGELYIAGAGVARGYLNRPDLTEKVFLPDPFTKTNGLRMYKTGDLVRCLPSGDLIFLSRNDRQVKVRGFRIELGEIETHLTQHPIVREAVVVALDEGPTKRLVAYVVADTTEELAYLLREYISSKLPEYMIPTAFVRLDALPLTPNGKLDRRALPEPERDAFVSQVYEEPHGEVEKALATIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MFW4</accession>
    <name>A0A9P6MFW4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Phospholipid-transporting ATPase</fullName>
            <ecNumber evidence="12">7.6.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BGZ80_007024</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="18 12">
            <text>ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.</text>
            <dbReference type="EC" id="7.6.2.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out) + ATP + H2O = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66132"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:66133"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Membrane</location>
            <topology evidence="1 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.6.2.1" evidence="12"/>
    <dbReference type="EMBL" id="JAAAID010003527">
        <property type="protein sequence ID" value="KAF9997357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MFW4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140326">
        <property type="term" value="F:ATPase-coupled intramembrane lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032456">
        <property type="term" value="P:endocytic recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045332">
        <property type="term" value="P:phospholipid translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006892">
        <property type="term" value="P:post-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000026">
        <property type="entry name" value="Phospholipid-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000001">
        <property type="entry name" value="Phospholipid-transporting ATPase IC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006539">
        <property type="entry name" value="P-type_ATPase_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032631">
        <property type="entry name" value="P-type_ATPase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01652">
        <property type="entry name" value="ATPase-Plipid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092:SF150">
        <property type="entry name" value="PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092">
        <property type="entry name" value="PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16209">
        <property type="entry name" value="PhoLip_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11 12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 10 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="351"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="395"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase N-terminal" evidence="15">
        <location>
            <begin position="87"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="14">
        <location>
            <begin position="182"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="35"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="active site" description="4-aspartylphosphate intermediate" evidence="9">
        <location>
            <position position="464"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="464"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="464"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="465"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="466"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="466"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="16">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU362033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF16209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAF9997357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="476" mass="52882" checksum="D5C404F1D14CDC98" modified="2023-09-13" version="1" fragment="single">MRGHSSKEFSEMNIPLTSAEGQFGGYDNNSNASLNSPSYSQPHSQYPPNSSSTAGSGKVHKPPSAFKSFLSNFTSNSSANQEGIRIIYLNNPERNSQGKYLHNRISTSKYNYFTFLPKFLFEQFSKYANIFFLFTACIQQIEGVSPTSRYATAVPLVVVLFATAIKEVMEDFKRHTSDSETNARKSKVLQGNTFVPKAWHSIKVGDIVRVEGGEPFPADLVLLSSSEPEGMCYIETSNLDGETNLKIKQALPETATLITPLDVSQLGGSIKSEQPNNSLYTFEGTLVMNGSHGHPKEIPLDPTQILLRGAVLRNTNWVYGVVIFTGHESKLMRNASATPIKRTSVERMTNVQIIFLFGILLAMSVASAIGNMVITNKNIEQLSYIETKTSSWADFGLSILTFLILYNNLIPISLMVTMEVVKFWQAQLINSDLDMYYEKTDTPALARTSSLVEELGQIEYIFSDKTGTLTCNEMEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MG87</accession>
    <name>A0A9P6MG87_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Periplasmic binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_006685</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003307">
        <property type="protein sequence ID" value="KAF9998935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MG87"/>
    <dbReference type="OrthoDB" id="409848at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38360:SF1">
        <property type="entry name" value="F12P19.7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38360">
        <property type="entry name" value="OS03G0120000 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040335051" description="Periplasmic binding protein" evidence="2">
        <location>
            <begin position="25"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="448"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9998935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="493" mass="53351" checksum="4D353B3E9B7DC8BA" modified="2023-09-13" version="1">MFGSFKKLFYASAALILLPVAAQAQGNCGGLVSNGTLGTFTVKYYTNFTVLTINGVNNNINSESYILYCGSEAPETLALTTVGLSESLGKFRAPLLQVAADDTYTSTYIEISGHRDTINLLENPQNIVSPCLQQRYANQSLFAFDNSFTEWSLVNAGFLSIMNAAQQKSVWIPASVEVDPLLRAEYITAVAMFYNDGVNGQSLYDQIKAAYTNLQNDMNQIPQANRNRIAWVYYDFTASTWKLRNSAFTKGIIAAAGGISFPLTGEVPDYATLSSDDIKTILLNSQVVIDQTDFTGQPTSAKTIDAWRTRAGFESSSDLPVLQSKKVYTLDGTTNSNGVSDYNYRVAPRPDILLKDLIYVQYPTYNSTYSTIFLNTNFATGGNGAGVVLTASNCGTTKYDSGDIPVIVPQPSFTGNPTPPPALVGTGVYGGDGTNSGSSSGGSKKVSIIVPVVCVVVILGAVFAFVSFKWGKRAKEDRFIELEEEMNNEIPLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MGF0</accession>
    <name>A0A9P6MGF0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">COP9 signalosome complex subunit 7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_006597</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003267">
        <property type="protein sequence ID" value="KAF9999269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MGF0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008180">
        <property type="term" value="C:COP9 signalosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045237">
        <property type="entry name" value="COPS7/eIF3m"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15350:SF5">
        <property type="entry name" value="COP9 SIGNALOSOME COMPLEX SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15350">
        <property type="entry name" value="COP9 SIGNALOSOME COMPLEX SUBUNIT 7/DENDRITIC CELL PROTEIN GA17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0736">Signalosome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="127"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="53"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="138"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9999269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="147" mass="16709" checksum="6FBF5E2C8F7E91C6" modified="2023-09-13" version="1">MDAIYQNVINANLDQKLKQVEVHSAMGRDLRPGQAQVMLRVLEDWTKTSETLLKALSAKMTQVQEDYEREKQAKEAFEQNLEKIKKDSANSGAGKHRKLVGSGSHMMDYEMGDQHMFQSPEFMGEFERMSYGGNSSKKSGKRVPHRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MGH7</accession>
    <name>A0A9P6MGH7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_006570</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003251">
        <property type="protein sequence ID" value="KAF9999434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MGH7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="219"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="146"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="294"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="343"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="57"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="146"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="294"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="356"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="376"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="402"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="433"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9999434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="489" mass="54193" checksum="E8FDD464C10B2DEB" modified="2023-09-13" version="1">MQSPAPVAPAGYRTPPPPPPHMVSNDPHAHTWSAPPPPQMHPSSSYPPPPPPPQEHLHHRAPSHPHPYHVAHSRTPSRSHSRTHSLSQPPQPPQQFAPQINVQSPPPPRHASPSAPITAPRYPQDLPYSERAIDPVRFPVISPQLHPAQQQQQLQQLPQQQQMLPQQRPPMQQLQQEDEEETDGEIIQSSVSVRQVAANGQMMMASSSSSAEEEQADSSKCPDCGKLYKHATSLLKHRWEHSMYWKPATKFLLSKHQQVQLMEAAAILLSMDDGHDSDKDPIVDMFIKQRGQLASGTSTASVSPSTSTKSLSASPPPMAERALAMKQEPIVNGASAAVMSPPASFHARTGNMTRHSVTSTTSIASSLSSTPPSLAPDDESVAEVDEEVMMTGPPHHPSSFRQQHQQQQQQQHLGQQPPPQMMMRGMEMGGQQKHAEPHYYQHDPRFAPGPFHHQQQHIPPPPPPPHHHIQAPHHQQIAQPYAPYYHDQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MHE8</accession>
    <name>A0A9P6MHE8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_006255</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003080">
        <property type="protein sequence ID" value="KAG0001012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MHE8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050493">
        <property type="entry name" value="FAD-dep_Monooxygenase_BioMet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789">
        <property type="entry name" value="MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13789:SF309">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_6G14510)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="7">
        <location>
            <begin position="28"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="132"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0001012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="144" mass="16237" checksum="C6DF892BC431EA73" modified="2023-09-13" version="1">MLDQFQDFPCAFGGTMKEIFDATPKDLISKVFLEEKVFQTWYNGRSVLIGDACHKLLPGAGQGAVMAMKDAVVLANCIYNMRDLSDKNIKTAFASYYRQRYPEADNVTKTNSVYTKMMFGHDRGSGRVLPQEGREEAERNPHAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MHJ7</accession>
    <name>A0A9P6MHJ7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hypoxanthine-guanine phosphoribosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">HPT1</name>
        <name evidence="3" type="ORF">BGZ80_006271</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003090">
        <property type="protein sequence ID" value="KAG0000911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MHJ7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004422">
        <property type="term" value="F:hypoxanthine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032263">
        <property type="term" value="P:GMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046100">
        <property type="term" value="P:hypoxanthine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032264">
        <property type="term" value="P:IMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032265">
        <property type="term" value="P:XMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43363">
        <property type="entry name" value="HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43363:SF1">
        <property type="entry name" value="HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0000911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="161" mass="18862" checksum="0B2640A8268F5828" modified="2023-09-13" version="1" fragment="single">KKNNKNISIQAIGLSLYEDLEIWKAAHQDQDGGPLTSEPEVIKTQWLNFDSSETSLIGRNILIVDEVDDTRRTLAYAVRELTKDLEKESQKLREQGKEVPETKIGIFVLHNKLKEKREELPEEIMKGRYFACREMPDQWLVYPWDALDIEDHTEKSRENTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MHR8</accession>
    <name>A0A9P6MHR8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006259</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003083">
        <property type="protein sequence ID" value="KAG0000980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MHR8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040172110" description="Secreted protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0000980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="118" mass="12560" checksum="C3E18C3350995BC6" modified="2023-09-13" version="1">MQKTLVLLSALFCAGIAQAGAPYFVLIKNDAGTQSTQFYEEYGARICQCVKNTQTGSITGQNGGDIKLFSSTDCTGNYETLGSNSVAKDTQWVNSLSFGASNIASSVDAGYCPNWYTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MHS6</accession>
    <name>A0A9P6MHS6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alcohol acetyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_006464</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003191">
        <property type="protein sequence ID" value="KAF9999947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MHS6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052058">
        <property type="entry name" value="Alcohol_O-acetyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010828">
        <property type="entry name" value="Atf2/Sli1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28037">
        <property type="entry name" value="ALCOHOL O-ACETYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28037:SF1">
        <property type="entry name" value="ALCOHOL O-ACETYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07247">
        <property type="entry name" value="AATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9999947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="280" mass="31561" checksum="C6EA253E7564A6E2" modified="2023-09-13" version="1" fragment="single">MALEVVRPLDLYARYLATYCSVDFFSNFLVAHKIQSTSANFSSWKSPQEWAQLLLHPISYLLDQHPSLALTIGDHLGDNPVYLRLESIDLQQLIRVIPIKTSEEIGRVIEQEHNTPFNLSDNTSPLWRLLISPIEDDNSSFYLSFVFQHSTSDGRSAMAMTEQFFEQLILEPKWTDKTPNLSPCATTKIPITSRKSIPAPIEGRVNCTPSKLKLLTTLAQSLPFVNSVMKIFETKYWAGDFDCSAGAPFKVELTLMQLTGQETSKVIQATKKRSTTVQSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MM20</accession>
    <name>A0A9P6MM20_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_004614</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002335">
        <property type="protein sequence ID" value="KAG0007481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MM20"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050562">
        <property type="entry name" value="FAD_mOase_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356:SF2">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356">
        <property type="entry name" value="FAD-DEPENDENT MONOOXYGENASE ASQG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="14"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="301"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0007481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="416" mass="46134" checksum="0C69233CC1E7E578" modified="2023-09-13" version="1">MSQDTPEANPRPNILIIGAGIAGLTLAILLEQINIPYHIFERAAEVKPLGSALSFDAGSLPVLEQLGIYEDLKQVSKAYTNVDFYNARLKKMGSLSGEEAFVASGYGTRIFCRPRFYEILLRRVPGHKISFKKKILRTVEKEGKVHIHCSDNTSYIGDILVGADGGYSGVRQSMYKLMDEKGVLPKEDLEDFTINYTTIVGVATPSNPEKYPKLKDEYSSFSQVIYGDGSNCYVITLPDNQISWGFGVQLSKSALKEMHFRNSEWDPEVKDTTLEQYRDFPCPVGGTMGELFDATPKHLISKVFLEEKMFKTCHNSRSVLIGDAWHKFHPAGGAGAQHAIQDAVSLANCLYSMKDSSLKSINSAFGEYYKQRYNRNDAKFKHSADIAKILNGQVKMEKGIGGGVIAVVSKVAQELD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMX4</accession>
    <name>A0A9P6MMX4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_004818</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002411">
        <property type="protein sequence ID" value="KAG0007320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMX4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0007320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="163" mass="17977" checksum="9646A2DFEC02E94A" modified="2023-09-13" version="1">MGKSEIAVLAVAIALREMEARLKLVTEKVDIGPDRELGVPDHGHVHGRLYVRETEVVHTQDTEVFHHVKTDLEAEDEEAPVTTAIVPHNEIRTIAMTIELSISVTALMNSRVGVVAVEAMTPVTDYMLKTEGHDLIIMIGETTIETTKDEMISPIEVDEGLKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MN11</accession>
    <name>A0A9P6MN11_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Deoxyribonuclease tatdn3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">TATDN3</name>
        <name evidence="6" type="ORF">BGZ80_003851</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Exhibits 3'-exonuclease activities and apurinic/apyrimidinic (AP) endonuclease (in vitro). Show preferential AP endonuclease activity on double-stranded DNA substrates and 3'- exonuclease activity on single-stranded DNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002044">
        <property type="protein sequence ID" value="KAG0008099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MN11"/>
    <dbReference type="OrthoDB" id="6079689at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01310">
        <property type="entry name" value="TatD_DNAse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001130">
        <property type="entry name" value="TatD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46317">
        <property type="entry name" value="HYDROLASE OF PHP SUPERFAMILY-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46317:SF1">
        <property type="entry name" value="HYDROLASE, TATD FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01026">
        <property type="entry name" value="TatD_DNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005902">
        <property type="entry name" value="DNase_TatD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <position position="5"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="7"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00093287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR005902-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0008099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="288" mass="31970" checksum="7647967359B6C594" modified="2023-09-13" version="1">MIDIHAHIYPPTIPSESINPLLQRAKAAGLTSLLSVSENLVDARHILRLSIQHPNFLFPCAGIHPAQPIRDADGATVGYRSAVESDLEGVFEFMEENVSRLVAIGEVGLDFTLAVLNSPHNDPQRLKTPEDVKTEQRKVFARQVRFAIQNNIPLNVHSRNAGHHAITLLEELDAKKVVLHAFDGQMKYVRRGLALGYYFSIPTSVVRLPQQQALVEEIPLELMLLESDTPCLGPEKGVSNVPSNLCFAAQEVARIKNLDLETVINQTTENAYTLFPKIRPHRPSLSSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MN27</accession>
    <name>A0A9P6MN27_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DDE Tnp4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_004400</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002246">
        <property type="protein sequence ID" value="KAG0007652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MN27"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027806">
        <property type="entry name" value="HARBI1_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13359">
        <property type="entry name" value="DDE_Tnp_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE Tnp4" evidence="5">
        <location>
            <begin position="400"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="209"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="294"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="337"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="655"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0007652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="695" mass="77097" checksum="0551A639BC43110A" modified="2023-09-13" version="1">MVSERKKLLAILERRQKLEDEYNATHNQAIKTEMDSFNPDLMRYFRITTLQGLQSLYPKTSDMRAAAEKQRYFAPRKTPQQRTGEIYEDLRRAGTDVDYLEFVRVSKSVFLSIVSSVLSQHQVFKNHSNNGQETVEKQLAITLWRLGHHGKDAGIGEASKIFGLSEGTIMKCTQRCMEALRDISLDIISWPVKGEKQTIKSRIRDLANSGSYHSSLSSTSMSTSTSTSLGPDYERIANGTISDAVGILSTMHVFLVSRPLLSETEEYLVPLPPSALNAAASLSSQDYYSKKKAASKKQISEEQEPITSTSRSANKKARVSKQGAIVSNLTNEGAENMAEDGCVSVPHRTGKRGRPRKDAQLVKSTPSPSDDPTLAPSTPPTTEKKVTRARPASFVKSAYLKRDYGYNILLVCDSTTRIRFADVVRPAGWPSQQVFTSSQLSLESETLFEGKDYLVADSGLVPGPHVVPMFPESQLEEEESSILAAASTSTKSRSKTQVVDPRRAELEHKKRLNESLKAVQKRAKDCQRKLKARFPSLLGMRVQLKNDPASQENARNWILACMTVHNLVLGDDASYNQAWEDQLEEMEAQRAEFDPNGRYELDDDRDALDDEYDEDGQGGMRVLNDNEMYELEDTPPPEAIGSIYASLPAMMEAHFGNSGQSGPSSALGGDGTMDMRDGLNAGRTQSGHSLRMLLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MN88</accession>
    <name>A0A9P6MN88_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pentatricopeptide repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_003394</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001896">
        <property type="protein sequence ID" value="KAG0008474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MN88"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051240">
        <property type="entry name" value="Mito_RNA-Proc/Resp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47933">
        <property type="entry name" value="PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47933:SF11">
        <property type="entry name" value="PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01535">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12854">
        <property type="entry name" value="PPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13041">
        <property type="entry name" value="PPR_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13812">
        <property type="entry name" value="PPR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="219"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="256"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="291"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="326"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="470"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="540"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="575"/>
            <end position="609"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0008474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="899" mass="103583" checksum="780E3BA0DE244205" modified="2023-09-13" version="1">MIRIFYDQHYPIHNPHSTSKRMLAHASVSDPCRSYHYAAKASVDQDMSQQQTPQQTQDVISPQINEASQTQRAITAFLAPPGSDRHHNPYETIADSFKINQPKSSEQLLPKVLMNDAVNSRNPQQIWHTYTRLTSRIVDPKGPPFSAAIYFRMLHCFQATRSRQTAKWALVVYEDMKKYYKPEIATLNTMLDILIRFENVEWAINFFQKDASLLKLSPNVRSYNIMIRGLAANGQLKAAEKIYHEMRQGTIPEKPQVATYSALMSQYIKNGMHAEADGVLDDMLKDNVKPNMWIFNSVIKRFVQRNDYTAARRVMALMKESDLKPDVVTYSTLIDGYARDGDEEAIANIQAEMARNKVYPNEKTITSTIKVFSRSNLDLDIDSRLEMLLKSLPPGEMNEHTFGVLVNVYGKRKDMSAAMGIYHHIISKGRQVNDVIMCSLLDGYVRSGDLPTANKLFHEHYTSKSVRPPSAWSYSAMITGCCKESNLHDALHYYHEMNSFQIEPDVTICSRLIQLYLEHHQLDNAQQMLRLMRNTGMNISVHTYTMLIDYMSSIKDIRSALRYYQEMLDSGIRPDVHCYTVLINAHIRSNDYTECNYYFEQMTKSGVQPTLETLTSMLHVHSLQGHIDQVRGFWTAITDMGFLPDIISFTVLMQTYSQQSNVEMVEFIFKEITQKELKVDTMTLTTLMRAYSDLPNLNVGRIDEILGMMEELELEPIPEYYRLLIDAFGRHGMPDRVVKIWSQFQGQEKPLAWVPSTSNLLHLIEACRDRGYIEILNSVWHSAVFGTSRENMVGSGTDSSTLQPMSRVNMLKPAPEVFTAYLNALLTHNRFQEIEDLLREGCRQMRMVPRNDDFELLFTGLAQYDFLKKELENMRQIVVERWPKVVPLVDRIIQSTKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MN95</accession>
    <name>A0A9P6MN95_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_004062</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002114">
        <property type="protein sequence ID" value="KAG0007929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MN95"/>
    <dbReference type="OrthoDB" id="2437116at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0007929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="56" mass="6480" checksum="0B8D9489502A767B" modified="2023-09-13" version="1">MVLDQIVNGEKNVTFPKYQGSSPLHERLFELAVTSLESYLEQQDQSLLKDAQYSQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNF4</accession>
    <name>A0A9P6MNF4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Dienelactone hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_003785</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the polyketide transferase af380 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002017">
        <property type="protein sequence ID" value="KAG0008163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNF4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051411">
        <property type="entry name" value="Polyketide_trans_af380"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47751">
        <property type="entry name" value="SUPERFAMILY HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G16580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47751:SF1">
        <property type="entry name" value="SUPERFAMILY HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G16580)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dienelactone hydrolase" evidence="2">
        <location>
            <begin position="20"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00029464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0008163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="297" mass="32431" checksum="A556036CA457D836" modified="2023-09-13" version="1">MTRTDVTFLSGPLKLAGHLYIPDSYKEGQKLPAIIGVHPAGGVKEQTTGTYCKELADHGFITLAFDRRYQGESEGTPRQYEQAFGFGEDVKSAVTFLSLQPQVDASRIGVLGICAGGGYALFAASSDPRIKAVGTVSAACYGSLLRTLPKADLDAILVQAGEARIEYAKTGEVKYLPIVPNIEDITEDSPNLMAEGSEYYNTPRGSHPRSISRTAIWAYDELLLFDAFAFIDQIAPRPILLVAGSKADTLVYSQKAYNQAGEPKELYLVEGSTHVDLYDRHLQKAAPKLIEFFKEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNS2</accession>
    <name>A0A9P6MNS2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">GDP-fucose protein O-fucosyltransferase 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_003518</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the glycosyltransferase 68 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001933">
        <property type="protein sequence ID" value="KAG0008385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNS2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046922">
        <property type="term" value="F:peptide-O-fucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006004">
        <property type="term" value="P:fucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11296">
        <property type="entry name" value="O-FucT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019378">
        <property type="entry name" value="GDP-Fuc_O-FucTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045130">
        <property type="entry name" value="OFUT2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13398">
        <property type="entry name" value="GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13398:SF0">
        <property type="entry name" value="GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10250">
        <property type="entry name" value="O-FucT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0294">Fucose metabolism</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="21"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="304"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="308"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="318"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="725"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00026232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0008385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="725" mass="81405" checksum="BEBE68E48E24ABB6" modified="2023-09-13" version="1" fragment="single">MKSLTGQCSNERSWRLQTKTYVILVVIIIISGWTLLINRNVTNHDVNHLDDLGLLEPAVTVLDSNTTYLSYLPHAGHANQFMSLQSAGLLAKKLNRTLIIPPIISNFHDHNNTHQRWSRYFDLPKFASLAGVSIVEWDQVRPLTPTQRKAGQDQATLGAQSDLLETDEWARVAENLTCQIIFGYGTSRLGINHSSWNFLWHFLFRPVFKEPPPPVPGMPDLSLAKIKGDPKAGHGLVAVDDIVARYRDNDEQMLMLSDTFKVIDPGYGGSRFWNEIGSHLHFIPQLMDFATSILDKEFQYDQGIEVSPNDDPEEVSPEDSTNKNPITTEPGDLSNAAILNITAPATRIPYIAVHLRRGDIGGKCSKENMYSKCLIPIELYEDAVARARTDAATRGLHSRLPVAVTTDTTSEDDIQKIEQLGWHRIDHSKYGTTELWGAFGEVMVDFAILAHADEFVGSPASTMTWVTALRQTSWYHRDAYYPNTIKSNTFIRGGSDCNPRYQSANTLIKFSVSEDTTLLVLITRPSFSFTPTKFNVMGFDVYFGNETSDRTSSSNTADDHDTNHFLPNLVPLETTVSLLDPNTKILSPTFYTTSEATAITTTTSARNRQQGSTTLVRPTGSRIHTPVSDSGVRLELRDYAALIVKEEMEKNQEITVLPNDDLEEEKGMMEVLSKDELMELSISTNKNPKRKRICRARKPGNIQNRHTQAIRIPIEAILWISDLKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNT7</accession>
    <name>A0A9P6MNT7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alpha/beta hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_003595</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001961">
        <property type="protein sequence ID" value="KAG0008311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNT7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0008311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="101" mass="11302" checksum="D84E004CDE400DD5" modified="2023-09-13" version="1" fragment="single">MSRRMSETASIKSFDSIPTMADVEATLGCVDMNQRYELYSGRLISFAEVGHPCGHPVFCFLGLGCMRYYSIILEDLAFKHSLRIYCIDRPGVGMSQPADPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQM4</accession>
    <name>A0A9P6MQM4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001862</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001438">
        <property type="protein sequence ID" value="KAG0010006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQM4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="203"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="398"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0010006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="439" mass="47836" checksum="10FB2717A3A415AB" modified="2023-09-13" version="1" fragment="single">AQPPQHGSEDRWAPPPGHHGRHPSDDQMRDVTHPQPSGERGQGMPRNPSGPEGFQGRNDIQPQPLGVDHERRDQRPGEHHNISHARPGSEQGVKDLRQGGYEDHQQQARGRDYEPSGAYPEQRGSPSTWPPQENRTGGYRDADQDQDEIAASLVSLSGKGPRGAVHRPQDDDYDMEEPEAEIPRGPPREDDSTSKRAHEQQHHQQQLQQQQQLQQQQQQHQQYQRQHSPSPHPSHDTREQTLPSRPISHSEMRRELQQEQQGREGGEENNVEDTPVRSSTPLQTMAAISAHQPRASSPRDVEPPQGMTGALSEGTLAADAPVPAIEPRERVSPTPSESVKEAEAPTNNGGDTRAGSIGVATSAPEAGGVPSDVQSGTFDHNVSKGPGGIVEKAPLAGADEDTEMEEGEVREDEDEVMSSGAVSTAAQGKEGSSKDEINK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRH8</accession>
    <name>A0A9P6MRH8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HECT-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="2">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_000937</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010001206">
        <property type="protein sequence ID" value="KAG0011117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRH8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00078">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2160.10:FF:000002">
        <property type="entry name" value="Putative Ubiquitin-protein ligase E3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2410.10:FF:000011">
        <property type="entry name" value="Putative Ubiquitin-protein ligase E3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2160.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044611">
        <property type="entry name" value="E3A/B/C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45700">
        <property type="entry name" value="UBIQUITIN-PROTEIN LIGASE E3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45700:SF2">
        <property type="entry name" value="UBIQUITIN-PROTEIN LIGASE E3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="HECT" evidence="6">
        <location>
            <begin position="644"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="5">
        <location>
            <position position="943"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0011117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="975" mass="109905" checksum="EB406038423C3C8B" modified="2023-09-13" version="1">MFDGSFKSRRTINLGGNKQQIDKQKLLRQAQEERRIREAERKQQKAAENIQAWYRGRTVAIKVRQDLRASWDQNISALLQSTQASPASPSSSVSIEQLSQGIESVTQKFLIFYRSQHDHQRLVQLCTLLQSPVSGTKSRFATIPFQLPQCRQSGWDVLLARLLPVLVRHLSDYPTWPENDSAPVLTLLDILTIQETFQVLGDSSLSSKLPVTLSRAMSGSGAIEYLARFLSRIVGDQSQEGSSTLDQLIVHILPVPLLPNRMSIESLTTFTSRLPLESILQRLSSTSCSSIVSLPLFRITPLVANILAFCYQRVSRMSPAVSSAYLRALTILLGMIPQDSIERAPKRAANDDEDMDDIEWRSEELPGATQSPTSSSNSTNLDPRILKWLSLAHDSNHLNDILGSIEPSSTPSDTQQEVLSTESVGQITQLLLNLITLFPSHKINILSNLMYFRFGGKVKQVSNPGSGKFFGISIIKIFLDAFMGTALYGQLLRSMEKDKQLSVQLVLDPAHEKSWSLLAFVSELYCQILVTMGDDEFHDESRNPISLSSVITLSSIVRDVSFLLWWNDNALDMELNLGGSKNLKVGYLRDIDRVAIFREFVESDRERTPGSSTFHPHAIGQARIRRGAVFEDGYDQLNNLGSRLKGRIAISFIDQYGMPEAGIDGGGVFKEFLTCLAHQAFDTNYGLFMNTTDQLLYPNPHSYAKQSAQLKHYEFLGRILGKALYEGILIDAAFAGFFLAKCLGQVNYLDDLPSLDPELYRGLMHLKNYDGNFEDLSLDFTVADEEMGQSISRNLVPNGNNIQVTRENRIRYIYLMAHYRLNTQIDQQCRAFFHGLSDLIDPRWLWMFNQQELQVMLGGAQTPISLKDLEENVVYSNFQRTDPTIEYFWSVVQEMGEEDRRLLIKFITSCARPPLLGFGELNPKLCIRNAGQEEDRLPTSSTCMNLLKLPAFTSRQRLKEKLLYAIHSEAGFDLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MS45</accession>
    <name>A0A9P6MS45_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001360</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001305">
        <property type="protein sequence ID" value="KAG0010583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MS45"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0010583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="86" mass="9405" checksum="429CE22D1B0A3631" modified="2023-09-13" version="1">MDQDKGYYAAQPPQYPQQAHPAYGQPVYGEAASYQPQPGYPQTPAQGYYAQPTPQANPVIIQQQPHPQNSADDCLLSAPAYVVVLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MS74</accession>
    <name>A0A9P6MS74_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">MIR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_001179</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001264">
        <property type="protein sequence ID" value="KAG0010792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MS74"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036300">
        <property type="entry name" value="MIR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016093">
        <property type="entry name" value="MIR_motif"/>
    </dbReference>
    <dbReference type="SMART" id="SM00472">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82109">
        <property type="entry name" value="MIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50919">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="MIR" evidence="3">
        <location>
            <begin position="178"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="33"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="70"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0010792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="241" mass="25820" checksum="2B79D4230D16F27B" modified="2023-09-13" version="1" fragment="single">DMLYPCACGSHSLSRLATASTGLLSSAPITTESNASMGGLGAKSPALASSSGSSGSNGISSSSRPMPKLSGSSSRSRSSSSTPQLGDKGVENAGSTIMPPPLCQYHTMIYKTTPSTTLFLHSHNYRSINHQDHNEVTGYKYHDSNNDWIVCRPGEGAEDYLPSAGGGSNVGENGQLLSPYLQWKDVYWLLHANTGKYLNSMASLKISQGFQEVSALESPHSNNDWIVEETTWLRQQILSDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MST9</accession>
    <name>A0A9P6MST9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_000608</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001128">
        <property type="protein sequence ID" value="KAG0011543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MST9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="209"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0011543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="250" mass="28491" checksum="612092D5750CB9B4" modified="2023-09-13" version="1" fragment="single">TRYTLYIMVRYEKVEGDIHIAWGFDDALDGFFLSVVDKRLAWRSESSDDVNKICEKVAMDGGGSYFDLNTYKNGGGFGHRVSDETILAFMLRYKIEISKMDLSKRKAEASDGGYSTMVMTPALPQHISPDSIMKRKARLQDAIVKSVNQPMPIVVARIDRTITELSDQYNIPIVRKGLFPPQTLSSTIFFFAQDAYPQGFQVCSHPDCCLPEKDEVKHKKCSRCKKAVYCSKDCQNDDWKTHKKNCQEIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MT91</accession>
    <name>A0A9P6MT91_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Biogenesis of lysosome- organelles complex 1 subunit 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">BLOC1S2</name>
        <name evidence="3" type="ORF">BGZ80_011466</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BLOC1S2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000924">
        <property type="protein sequence ID" value="KAG0012861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MT91"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031083">
        <property type="term" value="C:BLOC-1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0099078">
        <property type="term" value="C:BORC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000930">
        <property type="term" value="C:gamma-tubulin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043015">
        <property type="term" value="F:gamma-tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032418">
        <property type="term" value="P:lysosome localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019269">
        <property type="entry name" value="BLOC1_su2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46479">
        <property type="entry name" value="BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46479:SF1">
        <property type="entry name" value="BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10046">
        <property type="entry name" value="BLOC1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="30"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="77"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0012861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="190" mass="21004" checksum="54B08197BC7A86A5" modified="2023-09-13" version="1">MSPPTKSAATMALSQHQKVASASAIPRNKSFSVSPTPSSSSSSLRAQSLQSSLSQQTSNNNNNNNNSSSNTFSAAEAAKHLSEEHVARTSQDMFRKIAEYVRGEMLATGEDYKLLENMNVLTKERYSELAVVAQELMQEVGKLRTTYSDFEPYLARIDEISQQAETISNIAAELDEYTKSLETRLKRVTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUF9</accession>
    <name>A0A9P6MUF9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DNA-directed RNA polymerase III subunit RPC6</fullName>
            <shortName evidence="6">RNA polymerase III subunit C6</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">RPC34</name>
        <name evidence="7" type="ORF">BGZ80_010746</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000783">
        <property type="protein sequence ID" value="KAG0013958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUF9"/>
    <dbReference type="OrthoDB" id="613763at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006383">
        <property type="term" value="P:transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000116">
        <property type="entry name" value="DNA-directed RNA polymerase III subunit RPC6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007832">
        <property type="entry name" value="RNA_pol_Rpc34"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016049">
        <property type="entry name" value="RNA_pol_Rpc34-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12780">
        <property type="entry name" value="RNA POLYMERASE III DNA DIRECTED , 39KD SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05158">
        <property type="entry name" value="RNA_pol_Rpc34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028763">
        <property type="entry name" value="RNA_pol_Rpc34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0804">Transcription</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR028763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0013958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="306" mass="34690" checksum="DF79E4F7272C17C3" modified="2023-09-13" version="1">MVDSKSLEDLFYDECSKAGNNGLTTTDFLSVHKECDPKDTALAMNALLTKGYIEVFQVRGELIYKALKKEDVGKAGALHGEEQVVYNTIRSSGNEGIWTKHLKSKTNLHEAVIKRCLRALEQKALVKAIKSVKHPTRKLYMLMELTPSVEVTGGPWFTDQELDVDFVEQLTHQCYKYILMKSFPRDPSCIFTSSHNAYPSAAAVRKYIMEKRISQVELSVDDITMLLDVLIYDGKVERFIAQVDEDWDDEDMDTESDWVYKAVRDKKAESAWQDCPCGVCPVADFCTESGPVNPAGCTYYSKWLDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MV37</accession>
    <name>A0A9P6MV37_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Mitogen-activated protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">MPK1_2</name>
        <name evidence="5" type="ORF">BGZ80_010762</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000786">
        <property type="protein sequence ID" value="KAG0013923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MV37"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12087">
        <property type="entry name" value="TM_EGFR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="277"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="319"/>
            <end position="638"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0013923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="638" mass="69218" checksum="76540EB5855AC94E" modified="2023-09-13" version="1">MLCSLDEASGTFLYIFNDNVYLNAAKSTVISAWDSSRASAPQVIWPNSSVEGQFQWLGLIGGNWTTIDISAANGVSTPTPATVPKDVPTTGVYSIFRETTGSFLVLYNQNSNATTAARFNLTDAASTPLTLASPDIGYIHFSSVANAQDSSSDYFFGSDGKSTYTASAALNSSTIRMISTRHIPSDQFGPVPQLYDYGASTTVSNGKILIYGGLSNPTNNTWDFSMSMVVTNTGNSVDFNNYTIFSGDKTTTSGSFVITTPVPTTAPVQSKGLSTPAIIGIAIGAVALVMLIALFAVFHSRNKKIKARAREQEGLDMAVRDMHAKGAGGMAAYQPGFASTHSLLASEANTARGPNSVSTEQPVENLTLRVPIYRLGQTAVNSKMVVIQLGENVDTAESVTLKWVRDEIVWQREAAMLNHIVNPAKIISLHQTMIIPAALEWRHILVLDAHESTLDFMLSTHHQRILNRPDQMAVIRALLGGLVWCHEKDVIHLSICTGSLVMNEEGNWVIWSFGGARFLNEAVGPRQGSMIGQENGSVERNLAPELLNARRDHKLDSTLATTAMDAWAAGCVLFEVLTGQPLFRTEEAADQASTGRFSAWKDRLMEIQDPKERNVVEGLLHLDPNYRLSLSQAESLFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVJ4</accession>
    <name>A0A9P6MVJ4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_009979</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000649">
        <property type="protein sequence ID" value="KAG0015210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVJ4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0015210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="198" mass="22233" checksum="A18342102CE0B0FA" modified="2023-09-13" version="1" fragment="single">MSRDKMDSQSSAYLDILWINSALDRSPNAFFTAVNANNKQRAHKRYQQMIENCNLDSDDKKILLEKFETWKIDHAQQFWLDQRTQSSQMRVADVLVEGSEPYALQSIHRNVSRTHGDLATNRNASTSSHKNNSTSVVASSLDLPSVDVEAEQIDISVVEEDERDESAYSSNISPIPALSSTPTLTNTIRAVLSMLISK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVU6</accession>
    <name>A0A9P6MVU6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Vacuolar transporter chaperone</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">VTC1</name>
        <name evidence="7" type="ORF">BGZ80_009786</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000617">
        <property type="protein sequence ID" value="KAG0015550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVU6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033254">
        <property type="term" value="C:vacuolar transporter chaperone complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003807">
        <property type="entry name" value="DUF202"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051572">
        <property type="entry name" value="VTC_Complex_Subunit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46140">
        <property type="entry name" value="VACUOLAR TRANSPORTER CHAPERONE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46140:SF1">
        <property type="entry name" value="VACUOLAR TRANSPORTER CHAPERONE COMPLEX SUBUNIT 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02656">
        <property type="entry name" value="DUF202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="63"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="DUF202" evidence="6">
        <location>
            <begin position="27"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0015550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="128" mass="14278" checksum="7E28E68F96BE1F4B" modified="2023-09-13" version="1">MPTSSGQPLLQAIAGKRIALPVRVEPKVFFANERTFLSWLNFTVLLGSLAVGLLNFGDRIGRISAGVFTFVSMVVMVYALVTFHWRADRIRKRLPGPYDDRFGPTVLCVFILAAILINFGLRFSDKMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVW3</accession>
    <name>A0A9P6MVW3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">6-phosphogluconate dehydrogenase family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_010301</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HIBADH-related family. NP60 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000700">
        <property type="protein sequence ID" value="KAG0014694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVW3"/>
    <dbReference type="OrthoDB" id="435038at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029154">
        <property type="entry name" value="HIBADH-like_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015815">
        <property type="entry name" value="HIBADH-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051265">
        <property type="entry name" value="HIBADH-related_NP60_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43580:SF8">
        <property type="entry name" value="6-PHOSPHOGLUCONATE DEHYDROGENASE NADP-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43580">
        <property type="entry name" value="OXIDOREDUCTASE GLYR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14833">
        <property type="entry name" value="NAD_binding_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000103">
        <property type="entry name" value="HIBADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6-phosphogluconate dehydrogenase NADP-binding" evidence="5">
        <location>
            <begin position="8"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="3-hydroxyisobutyrate dehydrogenase-like NAD-binding" evidence="6">
        <location>
            <begin position="183"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000103-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF14833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0014694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="313" mass="34845" checksum="1DBCB9969CA92613" modified="2023-09-13" version="1">MQNQQDRVAWIGLGLLGYELTQHLQKYIASQSLPGLAVWNRTTEKATALQSIVPGIQVATSIDELFSKYKANIVFTSLQNDAIVEQVYEQLVSIASNVQYPIVFVETGTLYPRLSEKLEKQISSLPQNHVYLQCPVFGRPEAARLAQMVWVASGDQVAVERLKPYFNSMSRKVLDLKTTDVKAGSTLKLLGNFMIMSYTELVSESLNIAKKANLDPQHLISFVDEFIPAPAFQQYTRRIVGGAEEPDAVEMTVNIALKDVGALRQWGQEIGAPTPTADLVRENYVTAKEKGLTKNWNYLIDTINSTADNSSEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MW43</accession>
    <name>A0A9P6MW43_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_009609</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000590">
        <property type="protein sequence ID" value="KAG0015832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MW43"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="107"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="337"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="168"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="110"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="128"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="340"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0015832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="762" mass="86315" checksum="F6D5A609F1C7E6D4" modified="2023-09-13" version="1" fragment="single">MRSCQLRNSPLEFRQDPEGKYYCLLNNVQDIFPGETRFRINGTFVLPPSDENENENESMKIRYYPDNMDGTVTALGHSTLGPSDSNTQGHVNGILSQCQCQAQNLIPGPSFAPSPPMSPPLGMLSSPTNMSQVTSNSQVPHPPSSALTRGNSFGTQSKIIQQQVADFANNQLEVNQQILRRLDEAEERDLEASRQLVEMLKKQLESEERERKTLQELLKSEEREREMLQEQLKHKEMLQQANDRMVILQQGINAVLVQNYELHEYPIPRRFVILPEKFARKVIRGIEDPWDDTESSVSTDDGEDQEGLLDMIKNYDPRNLLEEKFRLYFLCECGEHTPAESSTENSSTCTSAQPTTNTKNKVHLAKHEGYELSRPTHFLKRYGPYVLGMLQILRFCLNAAKFVAPVVGLAKESLDSVVDDVKSISEQTLDAVNFSIAILEEELGRDSNIEALYSNRDGNDIFKNLAALEGADLRQLETFLRNKDKDKILGNLYRTTTSDGHVKWVCLEHFETSYRDNAARSFISTIETSHGFYDKKLRKITMALSSPITTKDFMKQLITYSFTTDELDLTLDFGFGSTDLSRIVKKLAQSNVRILKLDLKDTDSSRADFKLPGMEKYQPLLELMSNRKLQQLTLTGMDYFGSRTSDLPKNREHSKIRSFHHLNSIRTKDIPRLVNILSCCTNLVDLRLGSHTLSMYQLELGCAVGALTQLEVLHLIGLDNENEGNTKTYTEVNGNQYEEGILSKLVGGKVKLRELVVTGDLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MW93</accession>
    <name>A0A9P6MW93_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ATP synthase subunit delta, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">F-ATPase delta subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="primary">ATP16_2</name>
        <name evidence="16" type="ORF">BGZ80_010026</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATPase epsilon chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000656">
        <property type="protein sequence ID" value="KAG0015137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MW93"/>
    <dbReference type="OrthoDB" id="270171at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12152">
        <property type="entry name" value="F1-ATPase_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.15.10:FF:000003">
        <property type="entry name" value="ATP synthase subunit delta, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.15.10">
        <property type="entry name" value="F0F1 ATP synthase delta/epsilon subunit, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00530">
        <property type="entry name" value="ATP_synth_epsil_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001469">
        <property type="entry name" value="ATP_synth_F1_dsu/esu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020546">
        <property type="entry name" value="ATP_synth_F1_dsu/esu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048938">
        <property type="entry name" value="ATPD_C_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036771">
        <property type="entry name" value="ATPsynth_dsu/esu_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13822">
        <property type="entry name" value="ATP SYNTHASE DELTA/EPSILON CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13822:SF7">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT DELTA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02823">
        <property type="entry name" value="ATP-synt_DE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21334">
        <property type="entry name" value="ATPD_C_fung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51344">
        <property type="entry name" value="Epsilon subunit of F1F0-ATP synthase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="11" id="KW-0139">CF(1)</keyword>
    <keyword evidence="5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATP synthase F1 complex delta/epsilon subunit N-terminal" evidence="14">
        <location>
            <begin position="30"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="F1F0-ATP synthase subunit delta C-terminal" evidence="15">
        <location>
            <begin position="115"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00031669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF21334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0015137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="160" mass="17081" checksum="B85BD63770539370" modified="2023-09-13" version="1">MNFLARSVRAVRPVRMVRSYATEAAATGLRLTFAVPHQTLYKDASVAQVNIAAVSGDMGILASHVPSIEQLRPGVVEIIENAATKKFFVSGGFATMNPDSSLNINAIEAFPVEDFSAETVRHNLAEAQRVAASGATEEEKLAAKIEVEVLESLQAAINAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWD5</accession>
    <name>A0A9P6MWD5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NELF-A N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_009362</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000553">
        <property type="protein sequence ID" value="KAG0016212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWD5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056557">
        <property type="entry name" value="NELF-A_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23553">
        <property type="entry name" value="NELF-A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NELF-A N-terminal" evidence="2">
        <location>
            <begin position="24"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="148"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="259"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="347"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="388"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="400"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="429"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="441"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0016212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="553" mass="62048" checksum="8E95F75C8C9F7DC2" modified="2023-09-13" version="1">MERLKGEGVQDWLSQHLTAPWHGHQTVASELGNDIIANIKERWSQLESSVRLGVLFSLISLKKAQQIQLKDKCQELIDHACSDPDDWVRLVSQMLKEFPRDATLRFNVEQFADQAQLGSLLDELTSHRSFPSAGTGAAGSAIGAATPMGAPTSATGPAAAVSSSAGATPQTSTPLGPPGHPRPPAKSSSTGLFVRKPAGSFLRNNAPRPMPLSRNPSTGQLPLRSPRLDSPTTPRLNQKSSRIQILDIQQGNEIMQSMNDEKRRKEQAEQREKELKREQRQQELEAKRQQDAEKKAQLQREKDEKKREKEEAKKNKERQKQERDRQRQERDQDNDQVQTGETRGAPDNDDDDDGEDEGSLSTLPAKKRARINSSNSRRGSREDDNDYDNERLDRSREPLSPSTSSHNHAYSSQISMDDGRPTPAGASLSRGNNYSDSYFSQQQQLQQQQQQGSSVVSDNPTIFQDTNLLTAEDRAYIEAFLEGHPMKRPHENESLYQIVMNQKQVQDASGKIMYETILIEMNFDTGEWKKIKRRRAKPHVPTTATTSTIAMPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWG3</accession>
    <name>A0A9P6MWG3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Rad54 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_009722</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF2/RAD54 helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000607">
        <property type="protein sequence ID" value="KAG0015661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWG3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016817">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013967">
        <property type="entry name" value="Rad54_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08658">
        <property type="entry name" value="Rad54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rad54 N-terminal" evidence="5">
        <location>
            <begin position="225"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="107"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="313"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="29"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="107"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="136"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="175"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="218"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="267"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0015661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="444" mass="48198" checksum="BF1EF4DCED5D390C" modified="2023-09-13" version="1">MKRTFTGISLKRPASRITPSPSSDDTSSHSEGNASNSCSDGSENNSQTPPSSDPSLRSNATNLTDPFDSVVIDIPCISDYQAPGLKTILKKVPGAKSPIIKKVEFVDDSEGSLSDPDDQIYQEPRKKPVKRVMQQSKEDSLEDKENKDIIISIPEYNESQNAKSLDVKAIPQPPASNSKPTSKPSSKLETKPTVKPAAKKATKPAAKPLPSVTKTELSDNEDEDEYDEDAGNGDDSESDYDSESGSRKRAKTGRVTQQMIKDSIPKGTTRTTRSGRSPLTALKVTISSKPLVVKPVQPSSKTMMTLGKRFKVPTFTDPSKAPPPSRTGAFNLGVKRRPPVEAKSAHDYTMEGSIILYDPAWAQLDEAQREEEKLLQASQEAGTAGEEDATPQVIIPKKEKAKSKSIAEILGITKQKEVPKVHVVVCTSPIQIRFDAPIVYSAHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWJ1</accession>
    <name>A0A9P6MWJ1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_009660</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000599">
        <property type="protein sequence ID" value="KAG0015740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWJ1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="10"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0015740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="199" mass="22444" checksum="16DF66521D318F51" modified="2023-09-13" version="1">MSRSDPIHLPEITALIAKHLDRQDLTRCLRVCKAWFNSFLILAWSACGSGMVNGLTFPNMRNLHLEFAIDDGLEIEDQFYVIKHSPRLNCLTWLSEAADKAESKEFGNLLKQGAWPHLKSLVLLIDMQDDDVALMLDGLNSPTNLGLAWSMFGPCAFKSIRRHLDTLRELDISGCSLRCFVFFPAAGGIQDWVHIGEKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWM5</accession>
    <name>A0A9P6MWM5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Small nuclear ribonucleoprotein 35kDa (U11 U12)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">SNRNP35</name>
        <name evidence="5" type="ORF">BGZ80_009714</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000606">
        <property type="protein sequence ID" value="KAG0015674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWM5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017069">
        <property type="term" value="F:snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051183">
        <property type="entry name" value="U1_U11-U12_snRNP_70-35kDa"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13952">
        <property type="entry name" value="U1 SMALL NUCLEAR RIBONUCLEOPROTEIN 70 KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13952:SF6">
        <property type="entry name" value="U11_U12 SMALL NUCLEAR RIBONUCLEOPROTEIN 35 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="7"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="58"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="60"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0015674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="154" mass="16847" checksum="DC02622F2227C6F9" modified="2023-09-13" version="1">MTSVASLSHYGAIEKAIVVRNKVTGISRRYGFVTFQDQQSALDLFKASRRHTISVRFRRQSTTASRNRSANILDSTAEDSTTDKASLDTDQDEASGIDGLDPFLDSSTVLVDFERSRVMEGWVPRRLGGGIGGKKESGQLRFGGGIRPFSFPIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWX2</accession>
    <name>A0A9P6MWX2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_009635</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Su(H) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000595">
        <property type="protein sequence ID" value="KAG0015784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWX2"/>
    <dbReference type="OrthoDB" id="5600360at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1450">
        <property type="entry name" value="LAG1, DNA binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015350">
        <property type="entry name" value="Beta-trefoil_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036358">
        <property type="entry name" value="BTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040159">
        <property type="entry name" value="CLS_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008967">
        <property type="entry name" value="p53-like_TF_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015351">
        <property type="entry name" value="RBP-J/Cbf11/Cbf12_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037095">
        <property type="entry name" value="RBP-J/Cbf11_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10665">
        <property type="entry name" value="RECOMBINING BINDING PROTEIN SUPPRESSOR OF HAIRLESS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09270">
        <property type="entry name" value="BTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09271">
        <property type="entry name" value="LAG1-DNAbind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01268">
        <property type="entry name" value="BTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01267">
        <property type="entry name" value="LAG1_DNAbind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110217">
        <property type="entry name" value="DNA-binding protein LAG-1 (CSL)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49417">
        <property type="entry name" value="p53-like transcription factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RBP-J/Cbf11/Cbf12 DNA binding" evidence="8">
        <location>
            <begin position="336"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-trefoil DNA-binding" evidence="9">
        <location>
            <begin position="490"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="49"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="109"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="173"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="231"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="49"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="62"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="125"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="173"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="231"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="243"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0015784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="829" mass="90615" checksum="C0DFF4B1FDC1A8CF" modified="2023-09-13" version="1">MRSPFPSAAQAYAESIDSDTASRHHPDARLTILPLPSLAALYPLEDNHASSGLPDNTSASTHHNETTADSSHRNLQVRLLHGNHQQNNPHLQQQRHQPIYQSYDNRFQKFPVPASSPLPNVKPSLAQQNPIRSSNKPEEESHFLTSPKAACPDYIGTSMESLLNAIEVHPALSASSPSRSPSPSSNGYTHSASSAPTSPLSSPRISTNDSHTNHISATNKARMSISHLLDDTPEDKHSKQKEQPQLQQRKQKSNSPKSSSPTFSTIDITKRKWSNLSSANFEEERNAKIRRSIQAHVSGHASESQSAPESSLNIATVFPRQVFDTKNPSTRYQMTTICCLHASVAQKSYGSEKRFLCPPPIVNIQAPQGDSKSALSSRPQVTMSVVCETSDGNNSLGQRSTLEDDHTGTFRYLYVTGSAKAKSFQLKLQVYGRACLPNGFISNESTHPDSEEGVFNTADLPEPYAVFDSAPIAIISKPSKKTAKARNVSSCILTGSLVSLFNRINSQTVRTKYMSVQDGEFCAKNSTWSSFSVTIVSNGPSNSARIGSPKSHHRQPAIQSSSPITYGAEIVLTETATGVQSDRLIVCKVENGRIQENATGPICQMQKVALMSTERNEDGEPVYLSAVGNDHQVGRYMDHSSASKTVLKYQPSTMASGNTDIMKPGSDDFLCWTIVGISKFEYTYFESLPADSEAHHPITPFPTLMRNPIYNAASHTLELVVSNFYSQIGSQTSQVPMHVWLGSRGPLTTHIIRRSVSNSVEPGCNGNVDQTTLLVDLPQGRYMGVAPDEKTLSLPLLFVRHSDGITYNSRATVVFTRPENGEGWTVSIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWY1</accession>
    <name>A0A9P6MWY1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_009716</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000606">
        <property type="protein sequence ID" value="KAG0015676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWY1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0015676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="117" mass="12679" checksum="06A556A8F31C0F7F" modified="2023-09-13" version="1">MKKNKPAILIRPGSHTPDATVRVYDSKKKFVGFINSAQGPGFQPLGRVTNVDATTGQLNFYEFDWDGTVFTAENSTMTPTAVAAGTYDIVVASQQKLTKGKYPADFEIFNLGSVTIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWY2</accession>
    <name>A0A9P6MWY2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Vacuolar proton pump subunit B</fullName>
            <shortName evidence="5">V-ATPase subunit B</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Vacuolar proton pump subunit B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">VMA2</name>
        <name evidence="10" type="ORF">BGZ80_009849</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex attached to an integral membrane V0 proton pore complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000627">
        <property type="protein sequence ID" value="KAG0015462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWY2"/>
    <dbReference type="OrthoDB" id="1735853at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033180">
        <property type="term" value="C:proton-transporting V-type ATPase, V1 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046034">
        <property type="term" value="P:ATP metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007035">
        <property type="term" value="P:vacuolar acidification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18112">
        <property type="entry name" value="ATP-synt_V_A-type_beta_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18118">
        <property type="entry name" value="ATP-synt_V_A-type_beta_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01135">
        <property type="entry name" value="V_A-ATPase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12240:FF:000001">
        <property type="entry name" value="V-type proton ATPase subunit B, brain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00310">
        <property type="entry name" value="ATP_synth_B_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055190">
        <property type="entry name" value="ATP-synt_VA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005723">
        <property type="entry name" value="ATPase_V1-cplx_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022879">
        <property type="entry name" value="V-ATPase_su_B/beta"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003235">
        <property type="entry name" value="PRK04196.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01040">
        <property type="entry name" value="V-ATPase_V1_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43389">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43389:SF4">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22919">
        <property type="entry name" value="ATP-synt_VA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039114">
        <property type="entry name" value="V-ATPsynth_beta/V-ATPase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="4 5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATPase F1/V1/A1 complex alpha/beta subunit N-terminal" evidence="8">
        <location>
            <begin position="34"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding" evidence="7">
        <location>
            <begin position="156"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="domain" description="ATP synthase A/B type C-terminal" evidence="9">
        <location>
            <begin position="388"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="489"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="506"/>
            <end position="516"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU366021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF22919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0015462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="516" mass="57728" checksum="3FA5E2DD6D091A8A" modified="2023-09-13" version="1">MDPRLSSREASVLHAAAVTRNYSIEPRLDYRTVAGVNGPLVMLDNVKFPKFSEIVELTLPDGTKRAGQVLEVQGKRAVVQVFEGTAGIDAKQTHVEFSGDVLKMPVSEDMLGRVYNGSGKSIDKGPKVFAEDYLDIQGSPINPYARIYPEEMIQTGISAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVKKTKGVFDDHEDNFAIVFAAMGVNMETARFFKQDFEEDGSIERVTLFLNLANDPTIERIITPRLALTTAEYYAYQLEKHVLVILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVDGRNGSITQIPILTMPNDDITHPIPDLTGFITEGQIFVDRQMHNRQIYPPINVLPSLSRLMKSAIGEKLTRKDHGDVSNQLYAKYAIGRDAAAMKAVVGEEALNQEDKLSLEFLEKFEKTYIAQGNYESRTVFESLDQAWSLLRIFPKEMLNRIPQKLLAEFYQRDRKGRGRHSRDEGEVPAGEEDEGDDDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXA7</accession>
    <name>A0A9P6MXA7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">oligopeptidase A</fullName>
            <ecNumber evidence="8">3.4.24.70</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BGZ80_009642</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>Hydrolysis of oligopeptides, with broad specificity. Gly or Ala commonly occur as P1 or P1' residues, but more distant residues are also important, as is shown by the fact that Z-Gly-Pro-Gly-|-Gly-Pro-Ala is cleaved, but not Z-(Gly)(5).</text>
            <dbReference type="EC" id="3.4.24.70"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the peptidase M3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.70" evidence="8"/>
    <dbReference type="EMBL" id="JAAAID010000596">
        <property type="protein sequence ID" value="KAG0015774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXA7"/>
    <dbReference type="OrthoDB" id="534666at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006518">
        <property type="term" value="P:peptide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06456">
        <property type="entry name" value="M3A_DCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.390.10:FF:000009">
        <property type="entry name" value="Oligopeptidase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1370.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1370.10">
        <property type="entry name" value="Neurolysin, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034005">
        <property type="entry name" value="M3A_DCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024077">
        <property type="entry name" value="Neurolysin/TOP_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045666">
        <property type="entry name" value="OpdA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045090">
        <property type="entry name" value="Pept_M3A_M3B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001567">
        <property type="entry name" value="Pept_M3A_M3B_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11804:SF83">
        <property type="entry name" value="LD37516P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11804">
        <property type="entry name" value="PROTEASE M3 THIMET OLIGOPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01432">
        <property type="entry name" value="Peptidase_M3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19310">
        <property type="entry name" value="TOP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2 9" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Oligopeptidase A N-terminal" evidence="11">
        <location>
            <begin position="137"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M3A/M3B catalytic" evidence="10">
        <location>
            <begin position="346"/>
            <end position="819"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00026100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF19310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0015774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="827" mass="93468" checksum="EA8F9AEF8FD9CFCE" modified="2023-09-13" version="1">MLRSITSFTTSSQRLAAASPHVRQLRSCMPRMSARNNSSFIGLGQPAPLRSRVQPSRRLQLMGSASKHLISGAPLTIRRALATLSDIPSNYKKSSSVSNATLSGGKDSPEFTTNPILTWNEFPDFGAIKPEHVVPAMEALVQYVEKAFTERSQNFTPTWEGTMGMTQDLDDDLERASGVITHLSMVKDSPELRKAVEEIQPMLVKISLKMGQSLEFYDALVKMRNDEKTWNSLDKEQQRIVDKTIQGMRLSGVAFGLEGEGNAEKRKRFNEIQERKAQLNLKFSNNVLDATKAYVKIIENKADLDGCPKSLMQSMAKNAQAKGHGTGDAENGPWAVTLDHPTFVPFMMNVKNRELRETVYYAQLKKASEGEQDNEPIINEILSLRKEESAMLGFPSFGAMSLSKKMASKVETATDILDRLYKATLPAAKRELEELTEFAKQRLNHPTPLRPWDVSFVGEEYRKDRFKYSADQISEYLVFPRVIDTLFEVSKDSFGIHVSEVDAAEQAKTGLTTWHKDVKIYKVQDDGPEKKLLAYFYGDFYARSEEKRSGAWMDVCVTRMKDPSTGNVRVPIAYMICNQPPPLSDSEPSRMKFQDVTTLFHEFGHCLQHMLTTVDYPQASGIKGVEWDFVEVASQFMENFAYEPQWLDRMSRHYKTNEPMPQDMKETVMKSRQCLAGMAMMRQIHFATLDLELHTNYTPRAKDSTKDGDSVFDVDRRIAQKTCLVPPVPEDRFLCSFSHIFGGGYAAGYYSYKYSELYSADAYAALEEQAQSEDSRKRIGRKYRDTVLAYGGATDPRQVWKEFRGRDDVQVDALLRHSGLTSASASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXR5</accession>
    <name>A0A9P6MXR5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Serine arginine-rich splicing factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">SRSF4_2</name>
        <name evidence="5" type="ORF">BGZ80_007915</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000415">
        <property type="protein sequence ID" value="KAG0017793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXR5"/>
    <dbReference type="OrthoDB" id="1099063at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12337">
        <property type="entry name" value="RRM1_SRSF4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12339">
        <property type="entry name" value="RRM2_SRSF1_4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050374">
        <property type="entry name" value="RRT5_SRSF_SR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003">
        <property type="entry name" value="RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003:SF51">
        <property type="entry name" value="SERINE-ARGININE PROTEIN 55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="3"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="97"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="167"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="169"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="181"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="192"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="213"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="230"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="243"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="290"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0017793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="302" mass="34611" checksum="CB14B2C3460B7BDD" modified="2023-09-13" version="1">MTTRVYLGHLSRDASDRDVEGLFKGYGRIREVTLKNGFGFVEFQDIKDAEDAVYDFNGKEFMGEKLVVELARGDRRRDERREERDDRRFGPPERTEFRIIVENLAHGVSWQDIKDLMRKAGQVTFADLSKDRDDEGVVEFSSERDVQNALKTLDGENLRGKPVALRLFDPSRDSVPRDLGRGGGGGGGGGGRDLDRYDGRRNRDYGDRDRRDRGGRRGRSRSRSRDRGGRRSRSRERRRSRSRDRGDRTDRDHNRDRERGGGRDRDRDRNPGRGNGGRRGSRSPASSKSPVRRGRSRSAGRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MY11</accession>
    <name>A0A9P6MY11_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">F-actin-capping protein subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_007549</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Heterodimer of an alpha and a beta subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Cytoplasm</location>
            <location evidence="1 8">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the F-actin-capping protein beta subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000389">
        <property type="protein sequence ID" value="KAG0018100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MY11"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008290">
        <property type="term" value="C:F-actin capping protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030036">
        <property type="term" value="P:actin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051016">
        <property type="term" value="P:barbed-end actin filament capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000902">
        <property type="term" value="P:cell morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.570:FF:000001">
        <property type="entry name" value="F-actin-capping protein subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.210:FF:000001">
        <property type="entry name" value="F-actin-capping protein subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.210">
        <property type="entry name" value="F-actin capping protein, beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037282">
        <property type="entry name" value="CapZ_alpha/beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042276">
        <property type="entry name" value="CapZ_alpha/beta_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001698">
        <property type="entry name" value="CAPZB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043175">
        <property type="entry name" value="CAPZB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019771">
        <property type="entry name" value="F-actin_capping_bsu_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10619">
        <property type="entry name" value="F-ACTIN-CAPPING PROTEIN SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10619:SF0">
        <property type="entry name" value="F-ACTIN-CAPPING PROTEIN SUBUNIT BETA ISOFORMS 1 AND 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01115">
        <property type="entry name" value="F_actin_cap_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00192">
        <property type="entry name" value="FACTINCAPB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90096">
        <property type="entry name" value="Subunits of heterodimeric actin filament capping protein Capz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00231">
        <property type="entry name" value="F_ACTIN_CAPPING_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0117">Actin capping</keyword>
    <keyword evidence="6 8" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="5 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU365078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0018100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="276" mass="31606" checksum="F4CB33CCFA07F3CE" modified="2023-09-13" version="1">MEEEPNPQLNLALDLMRRLPPQNAEENLASLVTLLPDLTEDLLNSVDQPLKVQTCQKTGKEYLLCEYNRDGNSYRSPWSNEFTPPLADAAYPSARLRKLEVAANEAFDTYRELYFEGGVSSVYFWDLDPGFAGVVLIKKVGDGNRRMKGAWDSIHVFEVQEKGRNAHYQLTSTVMLYMVTNKPDLGHMNLSGSMTRQAEQDYVVDDPSMHIANIGRMVEEMEIKMRHLLKDVYFGKTKDTVNDLRSVESLEKVRKQQEMQKEIASKLHERQQKTVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYD5</accession>
    <name>A0A9P6MYD5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_007912</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion outer membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000415">
        <property type="protein sequence ID" value="KAG0017790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYD5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140567">
        <property type="term" value="F:membrane protein dislocase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140570">
        <property type="term" value="P:extraction of mislocalized protein from mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17352">
        <property type="entry name" value="MFS_MCT_SLC16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19520">
        <property type="entry name" value="RecA-like_ATAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000538">
        <property type="entry name" value="ATPase family AAA domain-containing protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051701">
        <property type="entry name" value="Mito_OM_Translocase_MSP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45644">
        <property type="entry name" value="AAA ATPASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12920)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45644:SF3">
        <property type="entry name" value="FI08533P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="107"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="177"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="202"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="235"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="261"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="310"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="350"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="375"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="400"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="432"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="466"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="506"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="105"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="14"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="50"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="73"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0017790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="856" mass="94664" checksum="DFC1D9FC6C3C02F2" modified="2023-09-13" version="1">MPEISEISGKKATDTSPDASQSSRGSTIVTDWTGEQQQQQHQSHLESKNKGPNSLRRSNSAIGSQVDVEKAESWTSNPENKPNQPSTIDAVVVDEDPVVMESGARGILVVLGGFLLIFAIIGYVSIYGLFQTQYVNIYGPRGHTQSAISYIGSLASGFQFFFTIFAGPIMNKFGHKIILWAGCIIGTLALLCSSWCTELWQLYLAQGVMFGIGASFINLAATAIPPLWYDVHRGLAMGGAGIGGLVLGFVIPALINKVDIWWTLRIYALIYLVLTGFGALVMRAPRQLSGPPVPPREDIFRISIMKNPRFVLWFIVAAFFGFAYVIPFTYMPSYAQDIVGLDANVQGGHLLSIMSAANAVGRIVVGFAGDRLGAYPVALFSFLVAPLSCLFWMFAHSQGILIVFSIIYGFFCGAWFTLVASITSKLVDLEHLGSGLTLVFLINTPGNMFTLPIAGKIMDNSGYKSMIGFNMAMWFCTALFMFILIFWDLIRDHVRKTQMQPQTKKYLADLALFALSQAAFYYAFKYIIASMDPLKTKKKDAHEKSAKVLDRLGHRDIKLNEYEQVIASEVIHPEDIKVDFDQIGGLDSIIRSLRESVILPLNHPALFTSASGLLGAPKGVLLYGPPGCGKTMLAKALAKESGATFINMHVSTLTDKWFGESNKLVAALFSLAHKMQPAIIFIDEIDSFLRERRSNDHEITSMMKAEFMSMWDGLTTGEDTRIIVLGATNRPNDIDSAILRRMPKRFAVKLPSDEQRMNILKLMLAETKLEPKFDFQKLVQKTAGFSGSDLKEACRNASMLPLREYLRGKGSDKKGALDGIVLDREEVRPLRLSDFFQHEANEDSSAHVILEQESMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZN4</accession>
    <name>A0A9P6MZN4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Wd repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_005580</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the WD repeat cdt2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000275">
        <property type="protein sequence ID" value="KAG0019582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZN4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051865">
        <property type="entry name" value="WD-repeat_CDT2_adapter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22852:SF0">
        <property type="entry name" value="DENTICLELESS PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22852">
        <property type="entry name" value="LETHAL 2 DENTICLELESS PROTEIN RETINOIC ACID-REGULATED NUCLEAR MATRIX-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="153"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="373"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0019582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="432" mass="46956" checksum="FFEB6B4E59D1D017" modified="2023-09-13" version="1">MPSNATTRKAPLTDITHRTLTGRRSNNTSAQQVISLTCSAGAGEENSPARGLLDIFAAAQAGSIGRKRSLKLTSDDLANEARNLAVGDEDGTIHIVDTRRDNTHPEQTVQILAHHNAIFDLCWTRDDSKIISVSGDQSARLNDVETKTCLGTFSGHTGSIKSVSLKFGDDNIFATAARDGSILIWDVRCSSTTSPQGDTTYRPADRLLNVHASSTRTVPPKKTKHGSDGPNTASAVQYMKHNENIIASTGALDGSVKYWDVRKHGTYFKHDFPTPLQTSTYTPETKRAHGMTSMALSPDGSTLYAVSSDNHVYMFNAVSLGGPTARFGGSDFACSSYYIKMSVSPDGNYVAVGSCKDLYVWEVNRPDRKPLIFHGHEREVTAVDWAKDLGNGTQLSGCSDDATVRTWRANKELVEDCRENQSLQNIHGIVSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N020</accession>
    <name>A0A9P6N020_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ubiquitin-conjugating enzyme E2 J1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">UBE2J1</name>
        <name evidence="5" type="ORF">BGZ80_004579</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000232">
        <property type="protein sequence ID" value="KAG0020218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N020"/>
    <dbReference type="OrthoDB" id="1158011at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23799">
        <property type="entry name" value="UBCc_UBE2J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000086">
        <property type="entry name" value="Ubiquitin-conjugating enzyme E2 J1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="340"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="domain" description="UBC core" evidence="4">
        <location>
            <begin position="16"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="187"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="194"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="226"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="245"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="257"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="272"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="314"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0020218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="364" mass="40047" checksum="2DBC1DB45698D6B4" modified="2023-09-13" version="1">MASFQSIPAQYNKKSSAVKRIMQEARELVREPSTDFAANPLETDIFEWHFTIRGPEETDFEGGLYHGRILLPNNYPFAPPSLMFLTPNGRFELHKKVCLSITGYHPEYWQPAWGIRTVLVAVMGFLPTQSKGAIGGLDTSVEARKALAIKSKTWVCTTCQTENIAILPDVAPEDVVKASLKADEMPPEFSFGYEADKKKQQSTEGDSKDSDSNRDNEVIKDRDQESSPTATADTLLSTTPNVDGGHSDDADSKLKDTQTQSSPLSSVPATISSSHQHLHNNNNVSGSTSSTTSSSTPNSSISTSPIAGVRPRTEVQQRQQQQLQTQAQPLTLRRRVESSIPMWLDALILGLASILVAMLIRRFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0J5</accession>
    <name>A0A9P6N0J5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DUF803-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_006127</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000301">
        <property type="protein sequence ID" value="KAG0019234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0J5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008521">
        <property type="entry name" value="Mg_trans_NIPA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570:SF65">
        <property type="entry name" value="MAGNESIUM TRANSPORTER NIPA9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05653">
        <property type="entry name" value="Mg_trans_NIPA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="171"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="200"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="224"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="257"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="85"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="347"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="420"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="520"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="627"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="88"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="103"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="352"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="426"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="456"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="535"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="627"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="657"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="698"/>
            <end position="711"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0019234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="711" mass="77964" checksum="4F2606835FB955AF" modified="2023-09-13" version="1">MWPMDDFPEINILISVALNVQKYAHNQLHPTTEIDSKHHQTSLACVVEEDNTRSRNDTRRFQSLATIQSYDSEDEEGDIETAHVDTHSYQSSQCSRRSSIQSNLSNHNSDTSAQSDTITAPNRVGLDEFYSTDSASETEYLRSKAWWLGMMLMILGECGNFMAYGYAQASIIAPLGTVALVSNVILAPLMLKEPFRKRDLAGIVIAIIGTIVVVINSKENEIKQVIPTQFVLFTTSAIVGSGILYNDFDEMDFSKGFNFLTGCCMTFLGVYFITSKRDVDETVNPAIVASAEWALAPQTQFATIQHRPSLDSLAPTRAIYSVDNNRSGSLMEQGRIPVQSSGYVIPRPIRNGTVTESSGQNSTTPLLGSSSRHSASGSKDLSFITSSMHNALSAVGSAVGTHHTALLSLETMYGHTRKIEDRRGSEQSLSQNPAYSQRPPLGSRSSSVCSGVYPQYSLTTHPSSTSLVPTELNYGTSSQSLQTQFPRPNTGLATDPRYQVPYLQERSLSQDNSYKQLNKKISIPHLSKEQKEPKGTSSMKIKTSGTAGPRRRSDRHMFPSPSEQDFVTEVARSFDSISSTPKAAPKIFPGAILSASPPSHVAQGSEYAFQTLKSPVSASAYGNFDSYQNDSSRSNSAMSPVSDRSNSSLPPLPPSDSGPHPLIQQQQPFRKKKKRGGSVTCDSDSPGLPLQQTKHRQRSYEDDHKPYAHNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N164</accession>
    <name>A0A9P6N164_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003568</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000195">
        <property type="protein sequence ID" value="KAG0020810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N164"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0020810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="282" mass="32315" checksum="571CACFE0BE26DB5" modified="2023-09-13" version="1">MSHFTAPLPALSHFNNLQQYQSPFIDYMTFYEFSLCDDPLRTESWDQSTDWSYDRSFEVSPCYEDFISPFTAFDSEIEEEDIPHSYSNLWEIQLELGEIPDMISNNLLKPCPLSSYNRPASQIMQLHNHAEMEDEAEKELEKGDDDDENEEESDYEEGEEGMAWPSEVSIESEPPVQNEHLLRKLFFFGRKASPSTGVYQEQEYGDGDESEGEEDDNGWGVTVNHPVYGMLSSSLELKGGEFRYDRKDSGVFMHGCMDERPSPLEDDIQVFPVAVEHSGGDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N276</accession>
    <name>A0A9P6N276_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003376</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000189">
        <property type="protein sequence ID" value="KAG0020905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N276"/>
    <dbReference type="OrthoDB" id="10261556at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0020905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="270" mass="30351" checksum="E278F49D71378C94" modified="2023-09-13" version="1">MRDNPSPGVQVSQDQHRNGSLASLLGDDSKRKTLVCFDSIVVLRSVQDELVRLRPVKIGAYYSTLRAEHKQDTMSKETNVRPKSSSLVQRFGRAVRDPLLMTRGIVTLLAPLVTSSKYSKRLDLKKLVQAAKDMNARQRCWELIAKRFDIAHRCNQSCEGCTGSTFSARFPICLSPAAIKIPTGKRTDEEKQVGRRKLQGWRKKTYKKWAGEDEPMTDGETWILPDSAVDKLCKRLFHAATANGVRRPCSHLWVADNGGVPLRRGKGHPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N287</accession>
    <name>A0A9P6N287_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">SMG1</name>
        <name evidence="12" type="ORF">BGZ80_003129</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JAAAID010000181">
        <property type="protein sequence ID" value="KAG0021049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05170">
        <property type="entry name" value="PIKKc_SMG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1010.10">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050517">
        <property type="entry name" value="DDR_Repair_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003152">
        <property type="entry name" value="FATC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018936">
        <property type="entry name" value="PI3/4_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014009">
        <property type="entry name" value="PIK_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039414">
        <property type="entry name" value="SMG1_PIKKc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139">
        <property type="entry name" value="ATAXIA TELANGIECTASIA MUTATED ATM -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02260">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01343">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01345">
        <property type="entry name" value="Rapamycin_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51189">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51190">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00916">
        <property type="entry name" value="PI3_4_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FAT" evidence="10">
        <location>
            <begin position="256"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="9">
        <location>
            <begin position="901"/>
            <end position="1245"/>
        </location>
    </feature>
    <feature type="domain" description="FATC" evidence="11">
        <location>
            <begin position="1379"/>
            <end position="1411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1237"/>
            <end position="1291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1248"/>
            <end position="1257"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0021049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1411" mass="158615" checksum="92D5C6C55EF69366" modified="2023-09-13" version="1" fragment="single">EALIATNGSDAISGLYVWCRRAIKDMTKQSSSNKSKSSRTERSSQYPRYKNSCLNDGQALALSQVSLDWINTAISHAQNRYEQSAKEAMSLMRSLAPGDNNEDVSAPTEFLCQEISNSLSDLYSYQQLHTFMESISAKAYTHQTLMWSNNAMSRSLEEYCANEASQAWKSLEEFYESGSKDLLVPDALSFDRSGIIGRNFLFATKVYQHSDQQITELDRLRQQAFNMVQPPAEFLMSKGLRHAGGALIDAMMLNTAVSATPQALEEFMDQLALIPDELRMKLFHRNLRYWGRLDALVNLARKHAPGGDSVVLKQSNEFKFLLSKIARRSECHDFACNIPRTWVGTLSPEIQLEEAKAAVAKHDYSTALNASGRILGNIRKMAEASQDNQSISFLHSKIYLKMAKWSRSTKPQLSEDNLKAFEDILELEHQTQQLSTQARIESITATCLQKAIEIGTNYRKAWFAFGTHHYKQGWGILDELGSFRFHHPVATAANDALKGVLKNAGVDKVEEQVKNIFCVFVKHCASGQPFDESVAYESIRAHVMKIDEIAGSEIIISAIIDSFQTLLQRILESYRLAIHGYFRFLQFTALEFECNKPMSKANTDEQAEVEISQSAVSDEITATLRLLRLLAKHGGQLYDTFHENLIDINVSPWVSIIPQLFARLDHPEKPVQSLITDLLCKIGEQFPQLIVFHCVVGANSAHNSACQRRLLGLIGDFLNKSHPALVSQVQHFIRELGRITVLWEEVWHKKIMVSLSELKNVLHELTDQYQGLDAIAGLGAEDKNAVMSDNYRQSVMPLLVTFESLLDSNAHPESNHERWFNSTFRDRIRAALDSLRSPKAWNNLFEGFTMLKEIYMDLGKELSGTRVLQLSDLSPELASIQSSLIDIPSPDQGTGVTIRSFEQQVVVIPTKTKPKKLTLTGSDGKHYTYLFKGLEDLHLDERVMQLLRISNGMLQHDKESNSRQLSARHYAVVPLSDNSGMIQWVENTVSIFTIIAKWQHRELMCTRWMNDDNSTGPHQAPQRATEIYHEKAVAALKRSGLPSNHPRRQWPKSILLDLYHEMASETPADLLEREIWSSSPTPAEWWRKSTRFARSTAVMSMIGYVIGLGDRHLDNIMIDFTTGDLVHIDYNVCFEKGKRLRIPEIVPFRLSRNMLTSLGVTGVEGNFRIGCEQTMKVMRKNKEILVTLLEAFIYDPLVDWQIEATAAQGGVGGGGVGGAVAAGGAGFDLGQGIARDSHPGLITDAESETSSSSVANQRDSRSSIETNNSTRSLNSRRRLSNESVTSISSTSIKSTTTIDFNTKRWNAPAAEQVDSGVTNGPGVNYASLQQQQQQQQQQLLQQDHQQPVLPASHQRNAYAVHILRRVRHKLEGRDFEAGKKCKVTEQVERVIQEATNVENLANMYEGWTPWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2E4</accession>
    <name>A0A9P6N2E4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Guanine nucleotide-binding protein subunit gamma</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BGZ80_002901</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">G proteins are composed of 3 units, alpha, beta and gamma.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G protein gamma family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000174">
        <property type="protein sequence ID" value="KAG0021186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N2E4"/>
    <dbReference type="OrthoDB" id="19232at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005834">
        <property type="term" value="C:heterotrimeric G-protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031681">
        <property type="term" value="F:G-protein beta-subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007186">
        <property type="term" value="P:G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000750">
        <property type="term" value="P:pheromone-dependent signal transduction involved in conjugation with cellular fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.260.10:FF:000003">
        <property type="entry name" value="G-protein complex gamma subunit Ste18/GpgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.260.10">
        <property type="entry name" value="Transducin (heterotrimeric G protein), gamma chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015898">
        <property type="entry name" value="G-protein_gamma-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036284">
        <property type="entry name" value="GGL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041848">
        <property type="entry name" value="Ste18_fungal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28189">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28189:SF1">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00631">
        <property type="entry name" value="G-gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01224">
        <property type="entry name" value="G_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48670">
        <property type="entry name" value="Transducin (heterotrimeric G protein), gamma chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50058">
        <property type="entry name" value="G_PROTEIN_GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0488">Methylation</keyword>
    <keyword evidence="7" id="KW-0564">Palmitate</keyword>
    <keyword evidence="10" id="KW-0636">Prenylation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0807">Transducer</keyword>
    <feature type="domain" description="G protein gamma" evidence="11">
        <location>
            <begin position="15"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0021186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="72" mass="8580" checksum="551A42E1C3322F48" modified="2023-09-13" version="1">MPNEMRLQRQLEHNKRLREQYELERIPVSQASTLLIKYCMSNRDVFVTQVWGEMDKSEDPFMAQPKGCCTLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2K1</accession>
    <name>A0A9P6N2K1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_002402</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000159">
        <property type="protein sequence ID" value="KAG0021434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N2K1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0021434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="251" mass="27946" checksum="465267F49082F005" modified="2023-09-13" version="1" fragment="single">MPVEYQEFKFGPKKKKLNVISKSRRGQKFVYLPAVLKVFTIQDTAGFEAVGELVADGVNIDYILDDNDKIIPHCPGCVIELVYEAAHYGATSLAPYATPRTPMSLNGSVNQLSIKNKVPTDLDLTKPMSTTLTRRPTTDIQRLLNTLNPDIEQAVQSGRPLNAEATEDLIRKHLAAPTNVNNTQQYIAHNVGMLVQGVGKLKLQGNVLEQLAHKIIEMQQQALDRLALIKSKTEAILTQNYELLEYTIPRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2K3</accession>
    <name>A0A9P6N2K3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Type I HSP40 co-chaperone</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">YDJ1</name>
        <name evidence="9" type="ORF">BGZ80_000662</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000114">
        <property type="protein sequence ID" value="KAG0022265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N2K3"/>
    <dbReference type="OrthoDB" id="550424at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030544">
        <property type="term" value="F:Hsp70 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10747">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10719">
        <property type="entry name" value="DnaJ_zf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.110:FF:000041">
        <property type="entry name" value="Chaperone protein DNAj, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.230.10:FF:000001">
        <property type="entry name" value="DnaJ subfamily A member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.260.20:FF:000003">
        <property type="entry name" value="DnaJ subfamily A member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.230.10">
        <property type="entry name" value="Heat shock protein DnaJ, cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.260.20">
        <property type="entry name" value="Urease metallochaperone UreE, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01152">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012724">
        <property type="entry name" value="DnaJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044713">
        <property type="entry name" value="DNJA1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001305">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036410">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43888">
        <property type="entry name" value="DNAJ-LIKE-2, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00684">
        <property type="entry name" value="DnaJ_CXXCXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57938">
        <property type="entry name" value="DnaJ/Hsp40 cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="HSP40/DnaJ peptide-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51188">
        <property type="entry name" value="ZF_CR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="J" evidence="7">
        <location>
            <begin position="6"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="CR-type" evidence="8">
        <location>
            <begin position="128"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="CR-type" evidence="5">
        <location>
            <begin position="128"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="354"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="364"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0022265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="406" mass="44371" checksum="4EEA55471323FF4C" modified="2023-09-13" version="1">MVKETKFYEALEVDPNCSDAELKKAYRKLALKYHPDKTGGATSEKFQEISHAYDILSDPQKRQTYDQFGEAGLSGDGPGGMGGGLSPEDLFSHFFGGGGGRGGRPSGPRRGKDVAHGLKVSLEDLYKGKTTKLALQKNVICEHCEGKGGKEGAVKTCTTCKGQGFRMMLRQMGPMMQQIQQPCGDCRGEGEIINPKDKCKFCNARKVTQVRKVLEVHIDRGMKDGRKIVFSGEGDQAPGTVPGDVVIVLEQREHERFKRSGDDLFYDAKIDLVTALAGGKIQIPHLDDRVLIVEILPGEVIKPGELKAVMGQGMPTERHHDFGNLYIQFEIEFPAPNWTDPSKIEQLRSILPPAAELPAPPKGAHIEEVSLTEMDPRQKARAEQGHMGGDDDEEGGGHPGVQCAQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2R0</accession>
    <name>A0A9P6N2R0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_010508</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000074">
        <property type="protein sequence ID" value="KAG0023047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N2R0"/>
    <dbReference type="OrthoDB" id="3044029at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040113967" evidence="2">
        <location>
            <begin position="21"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="184"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0023047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="269" mass="27022" checksum="5F2EF24FE41F0F6F" modified="2023-09-13" version="1">MRATITLLASTALLALGVSAQGQIAALESASSYCFFLPPSPGGDIAANEDSAIAFCNQANSNAPGAKIFPDGFVLSAHWATGDGWVQITGQIDPSKYSLSPCDQGGQYDIRAPVGASCAGYGYFVNVIEPYDGVYGMRCCTNKGDCNVSQSTYGVRVIFGSQYDFSGPRADGPVPGADQCGGNTTTTTTTGATTSPTTTALPSSTSANGTTTIAQTSTTTVHASSSSASATPTANSTTTTPNSTSAASNNKIAMAATALLACVAGVLIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2V3</accession>
    <name>A0A9P6N2V3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="21">Chloride channel protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">BGZ80_001799</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000142">
        <property type="protein sequence ID" value="KAG0021733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005769">
        <property type="term" value="C:early endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005247">
        <property type="term" value="F:voltage-gated chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03684">
        <property type="entry name" value="ClC_3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06093">
        <property type="entry name" value="PX_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05123">
        <property type="entry name" value="STKc_AGC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000008">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3080.10">
        <property type="entry name" value="Clc chloride channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014743">
        <property type="entry name" value="Cl-channel_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001807">
        <property type="entry name" value="ClC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017892">
        <property type="entry name" value="Pkinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045270">
        <property type="entry name" value="STKc_AGC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45711">
        <property type="entry name" value="CHLORIDE CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45711:SF3">
        <property type="entry name" value="CLC CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00433">
        <property type="entry name" value="Pkinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00654">
        <property type="entry name" value="Voltage_CLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00762">
        <property type="entry name" value="CLCHANNEL"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81340">
        <property type="entry name" value="Clc chloride channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0868">Chloride</keyword>
    <keyword evidence="11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="12 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="1306"/>
            <end position="1330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="1342"/>
            <end position="1360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="1380"/>
            <end position="1400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="1421"/>
            <end position="1438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="1499"/>
            <end position="1518"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="1524"/>
            <end position="1548"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="1555"/>
            <end position="1578"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="17">
        <location>
            <begin position="367"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="18">
        <location>
            <begin position="634"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="278"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="728"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="793"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="865"/>
            <end position="1080"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1212"/>
            <end position="1234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1728"/>
            <end position="1786"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="314"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="730"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="868"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="905"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="926"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="936"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="957"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="1008"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="1024"/>
            <end position="1039"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="1055"/>
            <end position="1069"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="1762"/>
            <end position="1779"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="396"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAG0021733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="21">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1899" mass="212417" checksum="7080025A0B1CDACD" modified="2023-09-13" version="1">MPEQTERRRSWWDILTPNDKAPTHTGVRSSQPDLLAAYDQQDLEAKSRIFDSMSESDAPSIAPNGVESESKLIVTGAGSSSEESLRRTSSKMDLFKKSSFPKRGKSKGGSKFATITTAWSSNRSTPPGRATTGSVSSITIDLNQYENMGDSNDVMVFTISEQQELIDGERVRDVAYTIRAEGMTKIILITRRITDFLEFDGKVHKKPLIQKQFPKSRPALPLLDDRRKSFLVSTRQFFFPRKNIAEKLENYLRKVASHEPLRSSAIFQEFLAPSKEGDLVHSKEQPHYPPFQDSKSDASFGSSSEQGEQRIPTSQSATNSASASSESLSEEAIQIRKEMAPRVRGNRVRPALPQVQEQRKKASVEDFQLIRVLGKGCMGKVFLVREHKSKKLFALKAISKEWVILQREIEHTKSERNILANVARISHPFLIKLRHSFQSNAQLFMVLDYYPGGDIATQLAKWHRFEPARCLFYAAEIVLGIEELHRQGIVYRDLKPENILLALDGHIVLTDFGLSKQFPSFSGSSSSLAENKTNTFCGTAEYLAPEILRAAEYSYAVDWWSLGTLLYEMLSGITPFWAENHAQMYQRVLEDDLEFFMEIEQDAADFISGLLERNPDNRLGSGGACDVKSHPYFSSIDWDVAMQRKLPCPYIPELVSEEDLSNFDDAFLTMTPRLSPGNHTLSNSIQNCFQGYSYTDKMASTFPRSDSKILMDRSNDSVSGSYVEDFDQEGTVTKPETNGLSNGKGHQPLYRSPLQQVDTQGEGTDAGSEGENTHQFRPFAQLYAPPSAAISAPIETKASPTLTPPTTYPEDGRMSVERISTSRIGAAADILRGYSERTTNPAFSPANQPRRSLSTQLAPDYHDWVSDVSASPMNPSRPPSSGSRFLDAVTGRSKAQQGRARRENQPSFSGSTFTNSDGETGRNGDNDSEYGEDNSGEPQQDRTLTNSTIDGENAQNTSTPTTKLPPLSKSRIQVPDPSRPAFKLGAPITPKPRPQKIRTSHEAETEEPINQPTETSALLGNSNRPRDENENRWTNEGSRRRTPRYNGPNQQDVDGSDHVQDVATDRDSLRWPSSRRGRNKTLHDIHRSSIANINMVKEKLLPRRRSYYDDAKEALVKENNGIRIWYHNYTTIDWIHDFVKERVRLRHLRSLGGIRGMIKNRADSLKGWVLVTCEWDTVPQISGGASTFVAGALQTLFAGICVVMVTSDGTVSQQKSHGATKRRRPSSGGIPRSNSWTSMQSVLNASQPKKIAYFGAGSGIPEPLMVAAGLNMGKQGPLVHIGCCVGNIACRMFDKYNRNDGKRREILSAASAAGVAVAFGAPIGGVLFSLEEVSYYFPGKTMWRSYFCALVSAVLLKIINPYRVGKTVLFQVTYDRDWHLFESIPFFFISIFGGVYGALFSRFHMNYSRYRSRTWIGRHPVKEVLIVTLITCAIQWLNPWTRVNLLQLLTNLYSECTPLDNLNGMCAEEVDHIYPIFLLLAQVFVMKVFLNFITFGVKVPGGIFIPTMVAGAVFGRMVGLGVQWLIVMDCVIPGLYAMIGAAACLSGVTRMTVSLVVIMFELTGAMTYSLPIMIAVMIGKFVGDAFSPEAFFNKLIDLNEHPYLDNKKDYNTFGTAADICDRYLETIDVNEQNDVNSLRRKVEILAASGYSDGGLPILDRGILVGYIASNELAHALDLAEKKDPDCICVFRNRASSNVPATEIITSLSEARHIEHDFDLGLTASQIRRDPLGSKSQTEFDYDDDMQNYDGPIRYPNVSSRSRHQDRNTDSQDRDARPDRNNSYYDESILDQDSEVTYADDSRHFARSNERINSTGTFNLLRDPSHTMDFTPFTDQAPLTVSLFSSMDLVMELFIKLGIKYVCVVKAGKHYGMIHKKRLLSFLKENDEKQKRHDQRAGCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2Z1</accession>
    <name>A0A9P6N2Z1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">phosphoinositide 5-phosphatase</fullName>
            <ecNumber evidence="3">3.1.3.36</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">INP52</name>
        <name evidence="7" type="ORF">BGZ80_001078</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the synaptojanin family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the central section; belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.36" evidence="3"/>
    <dbReference type="EMBL" id="JAAAID010000124">
        <property type="protein sequence ID" value="KAG0022100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004439">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046856">
        <property type="term" value="P:phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046985">
        <property type="entry name" value="IP5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000300">
        <property type="entry name" value="IPPc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002013">
        <property type="entry name" value="SAC_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11200">
        <property type="entry name" value="INOSITOL 5-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11200:SF257">
        <property type="entry name" value="PHOSPHOINOSITIDE 5-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22669">
        <property type="entry name" value="Exo_endo_phos2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02383">
        <property type="entry name" value="Syja_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00128">
        <property type="entry name" value="IPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50275">
        <property type="entry name" value="SAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAC" evidence="6">
        <location>
            <begin position="151"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="863"/>
            <end position="957"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="987"/>
            <end position="1271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1296"/>
            <end position="1324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1409"/>
            <end position="1467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1072"/>
            <end position="1083"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1128"/>
            <end position="1142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1163"/>
            <end position="1177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1205"/>
            <end position="1222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1223"/>
            <end position="1235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1244"/>
            <end position="1253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1257"/>
            <end position="1271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1410"/>
            <end position="1428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0022100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1476" mass="161269" checksum="04CCD341BF56F777" modified="2023-09-13" version="1">MQSEVYLSYHGHSPRTIALKPCASNHFDTANNGHVLYFSPHDQPTANGRIKVSVRLEPGSEFNHGLYRKITSRPVHGCLGLMHVAKDTFIAFVTGCSKVGDIRPGESIYRIVSVRFFSLTGNTPDEDMIPAPIDPESDDPPSMMPHPCRELEKVLCNGAFFFSPQFDLTRSVQARAIKLSEKPVAESNQIFDERFLWNHFMVKELLAFRSHLDEQEREELDSRGLLIHLIQGYVGSQSFRTAVTQGQISIISRLGSKRAGTRYNTRGVDDNGNVANFVETETIISTTEWCFSYTQIRGSVPVFWEQQGLQLGSHKIQLSRGSDATKPAVRRHFEELLQKYEDIHILDLMGTKDSGEVTLSQEYKNQVEDLGPLLKHIHMTKFDYHSQVKGGNYDQVNSLLNYVRGDSERYGYFHHDLISDTIVQVQRGVFRTNCLDCLDRTNVIQNNLSKDAVESLLHNVLHQDNRFGSLRLIHSDLWVDNGDLLSKIYTGTGALKSEITRSGKMSFAGMLGDATKSLNRFVINNFQDKDRQEVIDFLLGKMSHQVPVAIYDPIHDSVASEMRARQGEYSQKVEIDVFVGTFNLNGKLPSGEPLERWLCFDEEVPEPDMYVIGFQEIVELTAKQIAVTDENKRRIWEHEVESIINRRGGTGLGGMAGNKGAVAIRMDFHETSICLVTAHLASGQDKLQERNDDFQNIDSGIAFARGRNISGHDIILWCGDFNYRVDMDNDQIRALVSQGNYFEIFMRDQLKRSIDYGEAFYGYKEGIIAFPPTYRYDIGTNNYDTSEKYRAPAWTDRILYRGRGILQRSYDRADIRTSDHRPVMSMFVLELVMLDSAVKEKMEEAIYRQNSTRSLVHDTSSAKKVNGLGSRGLLTPPLTEKIGNGYDRAPHSMGPKPSSESHQWWNDPLEEGVKRIPSKNKNPFEGDQTISESAKPKPSNGSSSPLHSRPAPPAPVVKKPVVDLLGDLSNENIGAPVLPITGIEKESKPFVPHSIPGQAGRASGCSGKSDEPPSIANKRVVPPPPTSRRAGGAITALPASPTIHKDSDGSLRRPAPPPPKKNGYISTNKDTDSDDDDDDDDDGYKDGGNKANIVPVSQAKDDNSGKALISRSKEDKETSQEPGDQEVLLKPSQLKQQQQQVPGSAANAMTKGRSNSDIELIRPSLSSVSSISSTYSSPPTPSTVAANKPKVLLPGLDQHGGNKPSAVSSPTISSMGLSSAGTSVSSGLGHSSSVLQRTKEFNSKSDATPTSKPIPQPSRTSVATTTTIAPTGTIVKEKGSLDGEDTATISVSELKKSFGSSGQGKAEASTPALGPKPSISSGKLSLPLKTMETAATTTGSGNSMAAVIPMVKPLSFSTPGTSTPTKKPSTPTGAGFTLANLPVVEATSSSPSKVKMAGMGSIQAAAVLKGKNETQRKSEEATVAEEVKPASGSVKQAIASLKANSGSEVPANRGVEGKDEVEEGEKMDAFAFWKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N377</accession>
    <name>A0A9P6N377_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Calcium-transporting ATPase</fullName>
            <ecNumber evidence="17">7.2.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">BGZ80_001001</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">Catalyzes the hydrolysis of ATP coupled with the transport of calcium.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16 17">
            <text>Ca(2+)(in) + ATP + H2O = Ca(2+)(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18105"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.2.2.10"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="17">Membrane</location>
            <topology evidence="17">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="15 17">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.10" evidence="17"/>
    <dbReference type="EMBL" id="JAAAID010000122">
        <property type="protein sequence ID" value="KAG0022132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N377"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005388">
        <property type="term" value="F:P-type calcium transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02081">
        <property type="entry name" value="P-type_ATPase_Ca_PMCA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000002">
        <property type="entry name" value="Calcium-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000039">
        <property type="entry name" value="Calcium-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000028">
        <property type="entry name" value="Calcium-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000018">
        <property type="entry name" value="Calcium-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006408">
        <property type="entry name" value="P-type_ATPase_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01517">
        <property type="entry name" value="ATPase-IIB_Ca"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24093:SF369">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24093">
        <property type="entry name" value="CATION TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 17" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 17" id="KW-0106">Calcium</keyword>
    <keyword evidence="4 17" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="13 17" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 17" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 17" id="KW-0813">Transport</keyword>
    <keyword evidence="3" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="149"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="193"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="390"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="431"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="922"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="961"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1059"/>
            <end position="1078"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1090"/>
            <end position="1112"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="19">
        <location>
            <begin position="70"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1223"/>
            <end position="1274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="1232"/>
            <end position="1251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="1252"/>
            <end position="1274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00038148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU361146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAG0022132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1274" mass="138290" checksum="D91CD4768501E211" modified="2023-09-13" version="1">MEKAEIYESTDVDLHRDEKTHDIYPDIPKNTSTSADTVVDTLSANNGPFSLNPDQLMKLIDPKSPETLESYGGVQGVLAALHADPTKGLSTANKPLAAVVSDITAHKDISPSSSVTIEEREQFFNRNVLPQRKPKTIFQLMWMALQEKILILLLIAAVVSVALGVYEDYGMKHEPEPRYNKDFTISDAEDPKISWVEGVAILVAVMIVVMVGSINDYQKEAQFRKLNAKKEDREVKALRNGETVLISIFDVVVGDILHLEPGDVISADGIFLGGHNLKCDESAMTGESDAVKKVTYEEYKKLEEAEAASHKTEVIHTNHEGIDVIAPQHHALHGADPFIISGSKVLEGVGIYVVTGVGPNSFHGKTMMSLRTEAEDTPLQVKLNGLAEQIAKLGSLAALLMLIILFIRYFITFKDGKPAAAAIVKSLVDIIIAAVTVIVVAVPEGLPLAVTLALAFATTRMLKDNNLVRVLAACETMGNATTVCSDKTGTLTQNRMTVVAGTLGINTRFIADAPEGEVNQRANIPINKHAVALSQLVRSIPSAITTLMHEAIAINSSAFESEDDKGKLSFIGSKTEVALLDFSKKIGGPDYRKLREAAPVAHLYPFSSERKSMATIVKMGPKKYRLHAKGASEIIMKRCDKVVQVSSAADQNIPLSEDDRNSEVKELELNGELQTQIHKTIISYASQSLRTIGIAYRDFESWPPAGVELNEDNEVPFAAVAESGMTLIGIVGIEDPLRDGVPEAVLACQRAGVFVRMVTGDNILTAKSIATQCGIYTQGGIIMEGPKFRALSEEEMDAVIPRLQVLARSSPEDKKTLVSRLKAMGEIVAVTGDGTNDGPALKMSDVGFSMGIAGTEVAKEASSIILMDDNFSSIVKAILWGRSVNDAVKKFLQFQLTVNITAVILTLVTAVQSSSQEPVMSAVQLLWVNLIMDTLAALALATDPPTPDLLDRQPEPRTAPLISFTMWKMIIGQSILQLVITFVLKYKGMDILNYYQLPDYLASRSDAASIIVPYVTFKEQELDTMVFNTFVFLQIFNEINCRRLDNRLNIFSGVLKNTYFMVIFVIMVVFQVIIVEFGGAAFKTEKLNGVQWVICVILGLLSLPVGVIIRLIPDGFFGVLKKWVDSSEPPHPSLPTFEGPAQNEIGRTNSFPASVSSRNNSLAGSGNGVYPNRDSLVWNPAITKVRSDLSVFKSIRGGRLSTDSDRSEHSIIHAGAMVPTLVASSVGTPGNSSSQVDVSNSSPRSSIGSRRGTTQPSEQPVNTQVAKMTTPNTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3G6</accession>
    <name>A0A9P6N3G6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_009468</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000057">
        <property type="protein sequence ID" value="KAG0023429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3G6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16116">
        <property type="entry name" value="Ubl_Smt3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000202">
        <property type="entry name" value="Small ubiquitin-related modifier I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019129">
        <property type="entry name" value="Folate-sensitive_fs_Fra10Ac1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022617">
        <property type="entry name" value="Rad60/SUMO-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10562">
        <property type="entry name" value="SMALL UBIQUITIN-RELATED MODIFIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09725">
        <property type="entry name" value="Fra10Ac1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11976">
        <property type="entry name" value="Rad60-SLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="2">
        <location>
            <begin position="15"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="221"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="312"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0023429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="335" mass="39269" checksum="467193742E09EC3B" modified="2023-09-13" version="1">MGDEVDKKPEAGSAEHINLKVVGQDHSEVFFKIKRSTQLKKLMEAYCDRQGKAVTSVRFLYDGERIQPTNTPNELDMEDGDSIDVMWATHHHTKPGKPHEEKTYETERDILIKNHRFLRSEKDDQDLTWEKRVAKKYDDKLFKEYALVELKYYKEGRIAMRWRNEKELFRGKGEESLGCDEPDGLNSWEVNFGYMEQGEKKNALVKIRLCEKCSAKLNYKTKHKRAPSHQDEQTSHSSRSHKSHKGRERRHSSDSRSKSEEGDMATKGDAREEQRKADSSQRKRSHHREARDDDEDMTESHKRHRKSPSSQRADRSETGHIELSSQDKERSKRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3I0</accession>
    <name>A0A9P6N3I0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_011438</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000092">
        <property type="protein sequence ID" value="KAG0022703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3I0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0022703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="90" mass="9116" checksum="BCA9A48DE485B16C" modified="2023-09-13" version="1">MASSDGPYVATSISTKTINQFSVSHGDASVSGQEHTDQVSPGADGVLWLGPVDLTIGATKDSSSGLSRVHASSVLTLETLSITIGGGDFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3X8</accession>
    <name>A0A9P6N3X8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex</fullName>
            <ecNumber evidence="3">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_004782</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="3"/>
    <dbReference type="EMBL" id="JAAAID010000024">
        <property type="protein sequence ID" value="KAG0024268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3X8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045254">
        <property type="term" value="C:pyruvate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006086">
        <property type="term" value="P:pyruvate decarboxylation to acetyl-CoA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06849">
        <property type="entry name" value="lipoyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.100:FF:000010">
        <property type="entry name" value="Acetyltransferase component of pyruvate dehydrogenase complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="entry name" value="E3-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045257">
        <property type="entry name" value="E2/Pdx1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23151">
        <property type="entry name" value="DIHYDROLIPOAMIDE ACETYL/SUCCINYL-TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23151:SF90">
        <property type="entry name" value="DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2 3" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="5">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="6">
        <location>
            <begin position="124"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="80"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="169"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="84"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="94"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="113"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="182"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0024268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="352" mass="37220" checksum="E03F493E37E94C28" modified="2023-09-13" version="1" fragment="single">MPALSPTMTEGTITAWKKKEGDTIATGDILLEIETDKAGMDVEATEDGILAKILANGSKVAVNEIIALLAEEGDDLSKVEIPKAKTAPKADAAPAKEEKKESPSTKKEEPKPSQQTASTPSSNLLSPAVAHLLLQNHIKDVTTIPSTGPKGRVLKGDVLAFLGKIKPRAAPEPTIPQPKTLPPTSQSAPAASKTPAAPASKPAAPGSAFTDTPTSNMRKVIASRLTESKSNVPHSYITRDIVIDNMMKLRHLLADELHVKVSVNDFLIKAASLALRDVPESNVQFVPGGDNAKQIKDIDISVAVATPTGLITPIIKGADVRGVQSISLVIKELAERAKKNKLKPEEYQGGSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N497</accession>
    <name>A0A9P6N497_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Mitochondrial import receptor protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">TOM22_1</name>
        <name evidence="13" type="ORF">BGZ80_001332</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Tom22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000013">
        <property type="protein sequence ID" value="KAG0024575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N497"/>
    <dbReference type="OrthoDB" id="10016939at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22884">
        <property type="entry name" value="TOM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005683">
        <property type="entry name" value="Tom22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12504">
        <property type="entry name" value="MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12504:SF0">
        <property type="entry name" value="MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM22 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04281">
        <property type="entry name" value="Tom22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11 13" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="117"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="117"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0024575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="142" mass="15838" checksum="AC1AE270F57A69F4" modified="2023-09-13" version="1">MVKLEEVSLDHVEEEEYTDTDSSSVYSSDEDEDDVDNIESIMDRILALQDVIPAKTRKSISDKCSSIYGWGKHGVKFLGNSAWVLTTSALLLVLPLMIELEHEQGLIEYEKMQQQSSQMLSQTSSGQQQQKKPASGIVPPGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N537</accession>
    <name>A0A9P6N537_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Mitochondrial carrier</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BGZ80_008100</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000043">
        <property type="protein sequence ID" value="KAG0023773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N537"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015218">
        <property type="term" value="F:pyrimidine nucleotide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990519">
        <property type="term" value="P:pyrimidine nucleotide import into mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049562">
        <property type="entry name" value="SLC25A33/36-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45829">
        <property type="entry name" value="MITOCHONDRIAL CARRIER PROTEIN RIM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45829:SF4">
        <property type="entry name" value="MITOCHONDRIAL CARRIER PROTEIN RIM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 10" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="119"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="206"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="328"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="82"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="82"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0023773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="419" mass="45558" checksum="7EB985714B89B5C8" modified="2023-09-13" version="1">MSGSSTAMAVSRGSGIIAPHWFLSFLTKNPSSIKVFRQGQQSPQQQYRRLHLLKKRITMSQGLPFFKKATVRAGATTGGTVVAVSSPDNSSPAPSATSNHIGHQANKDTSMRKKSERVQFSWVHFIAGGTGGMVGAIVTSPLDVVKTRLQSSLYKNALSESAAASRTGVASVLGHVKDTFVLLGAINFAAYGNGKKYFTDLNHGNESTLVHLSSAAMAGVVTATATNPIWMIKTRMQLQSEGKLRIYRNSFHCAIEILKTEGIRGLYKGLTASLLGVTEGAIQWVIYEHLKRTFAERRIRLAQSSDVMGGDSSSLRRAKYLVGGKHIEEWAEYLGSAGAAKFVASAITYPHEVLRTRMRQTPKGNEAVKYTSLLQTFRLVLKEEGVAALYGGLTAHMLRVVPNAAIMFFCYEAILHQFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N6G7</accession>
    <name>A0A9P6N6G7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_000467</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="5">Amino-acid biosynthesis; ergothioneine biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000011">
        <property type="protein sequence ID" value="KAG0024616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N6G7"/>
    <dbReference type="OrthoDB" id="659at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1580.10">
        <property type="entry name" value="paralog of FGE (formylglycine-generating enzyme)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024775">
        <property type="entry name" value="DinB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051128">
        <property type="entry name" value="EgtD_Methyltrsf_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019257">
        <property type="entry name" value="MeTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017805">
        <property type="entry name" value="SAM_MeTrfase_EasF-type_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005532">
        <property type="entry name" value="SUMF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042095">
        <property type="entry name" value="SUMF_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03439">
        <property type="entry name" value="methyl_EasF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43397">
        <property type="entry name" value="ERGOTHIONEINE BIOSYNTHESIS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43397:SF1">
        <property type="entry name" value="ERGOTHIONEINE BIOSYNTHESIS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12867">
        <property type="entry name" value="DinB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03781">
        <property type="entry name" value="FGE-sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10017">
        <property type="entry name" value="Methyltransf_33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="DinB/YfiT-like putative metalloenzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine-specific methyltransferase SAM-dependent" evidence="7">
        <location>
            <begin position="103"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="domain" description="DinB-like" evidence="8">
        <location>
            <begin position="435"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase-modifying factor enzyme-like" evidence="6">
        <location>
            <begin position="653"/>
            <end position="889"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF10017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0024616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="892" mass="101394" checksum="C4FD560DF1BCFE01" modified="2023-09-13" version="1">MSPTIIDLRLSTKAYQENLIEKPTGQAAYPSPLSAASQEYTGVGAVAMSLDDPKFSDSSDSDSLDGMTDSICLSGDSHSGSEVADNEETLTESTPAFDLPKMIISGLCPETPGKAKTIPTMVLYDDRGLQLFDEITYLEEYYLTQEEIEILERDGDKIVEHIPDNSIVVELGAGSLRKTVLLLNALERKRKNICYFALDLMLNELTKSLKSLGNFTNVKTAGLWGTYDQGLAFVSSLGSEVPKTLLWLGSSIGNLTRQEARDFISSYSKTLDVGDNWIIGIDRRNDAQDITIAYNDPKGITREFIMNGLDHINVVLGQNFIDREKFHYFAEYNVELGRHEAYYQVKESHELVYKDPSSETKKEVRIKLEKDELINVEYSYKWSLEESTQLFEQTEMTRLGQYTSASNRYDLHLIRKTPFYFKTTGSRPLPTQEEWAELWKAWDLITMSMIQHPSMLLEKPIDLRHPFLFYLGHIPVFLDTQISRVLNESFTEPAYFNVIFERGIDPDVDDPTKCHSHSFVPDAWPEIESIIEFRDRVRERLFRILNDTEKYTMTRRLARVLFMTFEHEVMHLETLLYMMVQSPNTLPPPSLTTHWSSKIGTDSVSSSSGTLPAATWISIDPSGLDAAVLALGHDDRESQDLFEENKTDVETALGWDNENPLVTSRTPPSAFKIQSRQVTNNEYLAYLMATSDKNLRDDDRIPASWLIRKSSGEDEICVGTVYGPTPLSVAGEWPVSCSNIHATGYSAWFSQKSGQSYGLPTEHELSIAFKLKQSTVPKTGLENYGFRQWYPTLDESCFKSRSNDAGTIENFSGPGGLWDWTCTPFEPLDKERFEVSKLYPGYSSDFFDEKHMVVLGASWATHPRIAERRSFRNWYQANYPYVFAGFRLVQRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SQR6</accession>
    <name>A0A9P6SQR6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Arm-like repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008645</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004755">
        <property type="protein sequence ID" value="KAF9992235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SQR6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056251">
        <property type="entry name" value="Arm_rpt_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23948">
        <property type="entry name" value="ARM_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arm-like repeat" evidence="1">
        <location>
            <begin position="157"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF23948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9992235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="242" mass="26615" checksum="1DB5919390D73744" modified="2023-09-13" version="1" fragment="single">MLLNDLGHHDKAKKSHGKAEKWGYVDVVGLDTGSSHPLSKSDTIRRSFLPTAALSVAPIVVAAIYQDNSKKRFNHQDHIFHPTPAEVNSSKSTPNKDVVHVSRKIFGQNITPPVAKYVLPEAGECIASTPQLVYCLSLLHPSMISKEELDQSECDWLQAKAADPNEQERLQTMVIDLIRAFVQEGFKKPSVVAEVASLAVVLGQDDFRKLLQVFVDGVNQSLLLDVHLLNGLAQLIRNAPQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SQU4</accession>
    <name>A0A9P6SQU4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Arm-like repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008953</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010005046">
        <property type="protein sequence ID" value="KAF9991694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SQU4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056251">
        <property type="entry name" value="Arm_rpt_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23948">
        <property type="entry name" value="ARM_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arm-like repeat" evidence="1">
        <location>
            <begin position="1"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF23948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9991694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="132" mass="14548" checksum="57BCC1E79646DA4A" modified="2023-09-13" version="1" fragment="single">MATDVIRAFVQEGLKKPDVVAEVVSLAAVLGQDDFRKLLQVFVDGINQSVLLDLHLLNGLAQLIRNAPQGHIDADDLVKILELLNARLKDTNKQSTQHTYQLATTISQVLDSMVDSQVEGLSHEQLHEPLSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SRL4</accession>
    <name>A0A9P6SRL4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Arm-like repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008378</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004515">
        <property type="protein sequence ID" value="KAF9992870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SRL4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056251">
        <property type="entry name" value="Arm_rpt_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23948">
        <property type="entry name" value="ARM_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arm-like repeat" evidence="1">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF23948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9992870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="106" mass="11267" checksum="AFB27E190F30ECCE" modified="2023-09-13" version="1" fragment="single">ALQYIPDDETILQSMMRRTGKVVQGISGVVSAVKALDLVGFIEGLQNVQQGVAGAEKVIGLVSDACSNAVALIENGQGLLASLKESLNFKHKGSWYPALRGLDRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SRM6</accession>
    <name>A0A9P6SRM6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007945</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004179">
        <property type="protein sequence ID" value="KAF9994005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SRM6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9994005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="63" mass="6932" checksum="CD4513D1C630EEAE" modified="2023-09-13" version="1" fragment="single">MPIKPNRSQRPHSNPNYPQVEVDTNAICFFTISETTQATNTVNPSLPVQALVQDTTPHPTSAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SSV2</accession>
    <name>A0A9P6SSV2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006867</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003419">
        <property type="protein sequence ID" value="KAF9998073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SSV2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9998073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="59" mass="6437" checksum="B635261E67CE1A70" modified="2023-09-13" version="1" fragment="single">RSSKSQSSSAPSTPSQTPRVSMQEDERPTQPIEKMTRDQAIGTIMSTAMANGTSRSYVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6STL2</accession>
    <name>A0A9P6STL2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Carnitine O-acetyltransferase mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">CAT2_5</name>
        <name evidence="8" type="ORF">BGZ80_006498</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the carnitine/choline acetyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003200">
        <property type="protein sequence ID" value="KAF9999864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6STL2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.70">
        <property type="entry name" value="Choline/Carnitine o-acyltransferase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000542">
        <property type="entry name" value="Carn_acyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039551">
        <property type="entry name" value="Cho/carn_acyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042231">
        <property type="entry name" value="Cho/carn_acyl_trans_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22589:SF103">
        <property type="entry name" value="CARNITINE O-ACETYL-TRANSFERASE, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22589">
        <property type="entry name" value="CARNITINE O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00755">
        <property type="entry name" value="Carn_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00440">
        <property type="entry name" value="ACYLTRANSF_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Choline/carnitine acyltransferase" evidence="7">
        <location>
            <begin position="1"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="557"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="570"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="163"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR600542-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9999864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="632" mass="69557" checksum="77F8DD55D686E7B0" modified="2023-09-13" version="1" fragment="single">YLFNYARIAGSPADSAVGFPTETNNHITVVRNGKFYIFETLHLPSKPSSVLSPREIMIQLERIKKMADDDNTNVPEVGILSTGQRDQAAKDRTTLFEAHFSNRAHMAKIESSIFVLCLDSTSPSTSEEFSRACWHGDGASRWFDKCFQLIVFANGRAGMNGEHSKMDATPTSRLCRFMIDEAQARDLPDFRNLNAEDLYECASALDKPKPLNFVTSKALDKAIADAHVYFKTTVEAHEMVPTEFKGYGKGLIKAFKMSPDAYVQMALQLAYYRKHGELVATYESAATRKYRHGRTETARSCSIESKAFCEAMDNPDMDLKARAAACRAAVARHAKYTAWAVDGQAVDRHLLGLRLIRKPEEPVPAIFSDPVFARSCRWRLSTSQISDDCFIAYGWGEVVPDGYGCAYMVKERELYFCVTSLQLGSREFGQHIVDALEDMRFMFEEVRKIEKAEAAQAALVAAALEAERAAAEATQRANQGDLEISTAVSTAAPALISRSPSPPAVSSPAPRTSLFFQKDDPVLRTALARNAMATAQEKYWSGIDDIAFDDTPTGSLGSLRIKAKPTSPTSSSANMSGMRSRSGSQQSGVRPRSDSGAQKRTFLAILMGEDSVLGRIRARRGTTSSNKSPLAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6STS2</accession>
    <name>A0A9P6STS2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">PDE1B</name>
        <name evidence="6" type="ORF">BGZ80_006041</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002988">
        <property type="protein sequence ID" value="KAG0001976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6STS2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004114">
        <property type="term" value="F:3',5'-cyclic-nucleotide phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1300.10">
        <property type="entry name" value="3'5'-cyclic nucleotide phosphodiesterase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023088">
        <property type="entry name" value="PDEase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002073">
        <property type="entry name" value="PDEase_catalytic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036971">
        <property type="entry name" value="PDEase_catalytic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11347">
        <property type="entry name" value="CYCLIC NUCLEOTIDE PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00233">
        <property type="entry name" value="PDEase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00387">
        <property type="entry name" value="PDIESTERASE1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51845">
        <property type="entry name" value="PDEASE_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDEase" evidence="5">
        <location>
            <begin position="1"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="63"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="287"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="355"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="409"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="501"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="570"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="71"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="308"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="443"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="501"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="532"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0001976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="641" mass="69824" checksum="C70A818C93819BB5" modified="2023-09-13" version="1">MDLVTKHSLFRNVSKSPAAMLPEGLPATEDTMRDAMVKAILATDMAFHYDMLNNLNNLFEATTSPVTSSDSEADTDSESEQDGLETSTTTQPRVHIETTEDLDVDQSKEVSVSISSPLSNLQETLRTKIEAHRQCRRDSCSSIHSQSSGEPEILASPQSIESLSISPEDLTPEQRQNLCNCLLHAADISNAVKPWTVCKRWSDLVVQEFFRQGDIEKAQSLPVSPNMDRDQHNQSKISLGFGDFVVQPYFEALVELLPKASPVLTSLADNRAQWVALQKSSNEFGNDPYLSIDPLEDPSMSRRSSSSEFEHMPPGRRVSDDSKLLRTPHRRLRHSTNAEITPSLALRRIKRSFSGRSLSSSMQNLHAHSPRSSLSSGRLASGQEILISTLKRQASMTEREMSSAFIHAQYGHHSSRPDESGDSYFGMQLPPPPPKSAQSFEPTTHKAVDQQKHKSISKSDSGNGGAGGGVFRQKRLASLQVGSPTPSNFLQEYSEGYVMPKNQSSTTENIPSSRDDPSLASSSSKPLHQGQAVPTSTQARNRSSTPAVMMNKIKYDWALSPTLAEIPSESRFGCGPLDDDENAATASPDPEKSSNPSLTTVATGITGIDPVSAGATQGTDGAVLISTAESPIERKALFTDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SUX6</accession>
    <name>A0A9P6SUX6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_005378</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002656">
        <property type="protein sequence ID" value="KAG0005846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SUX6"/>
    <dbReference type="OrthoDB" id="270970at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052981">
        <property type="entry name" value="Ingression_C2_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47052">
        <property type="entry name" value="CONSERVED SERINE PROLINE-RICH PROTEIN (AFU_ORTHOLOGUE AFUA_2G01790)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47052:SF3">
        <property type="entry name" value="INGRESSION PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2" evidence="2">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="253"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="280"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="300"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="319"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="414"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0005846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="424" mass="44912" checksum="31238BF73F5C5FF9" modified="2023-09-13" version="1">MTTPKIGVLVAIPIKGRKLMNRSGGKQSPYVQLKLGEQKKRTKASLIAAAEPEWDQEANVFHGQMDMNVSVYDEGKKNELIGEGILLLHEVVDKGELDVWFPIKYNGTAAGDIYFELTFYASAPPPTAGGTPPIPQAQIQTPVGHIQPGYPGPGVHPLPHTPPVSGFGSPAVGQPTPFLPYNATPRPFPASPYPAAAPFGVPPVSGPGYNQPFGGAPPFRPPGASPYPTNATPQFGSPNAPGGGYPQMPQPFPGSNTNYPPNNNNINNMPPRFPAPQHPSPGGQQIPSFPQGPGGPPNSFPSNGPNNNYPNNGPPPNFPNNNNFNSNGPSNNNFNQNGPNNNFNQNGPNNNNFNRPNNSFSGNGPNNFNGNGPNNFNGNGPNNNNFGNNGPNNNNFNNNYNNNNQPGAPVTPLVQYNNSLGSFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SUY9</accession>
    <name>A0A9P6SUY9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">rhizopuspepsin</fullName>
            <ecNumber evidence="3">3.4.23.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_005534</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of proteins with broad specificity similar to that of pepsin A, preferring hydrophobic residues at P1 and P1'. Clots milk and activates trypsinogen. Does not cleave 4-Gln-|-His-5, but does cleave 10-His-|-Leu-11 and 12-Val-|-Glu-13 in B chain of insulin.</text>
            <dbReference type="EC" id="3.4.23.21"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.23.21" evidence="3"/>
    <dbReference type="EMBL" id="JAAAID010002725">
        <property type="protein sequence ID" value="KAG0004917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SUY9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.70.10:FF:000115">
        <property type="entry name" value="Lysosomal aspartic protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF51">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040339262" description="rhizopuspepsin" evidence="9">
        <location>
            <begin position="20"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="10">
        <location>
            <begin position="86"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="23"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0004917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="289" mass="30177" checksum="DF7ABBF4E75E71A7" modified="2023-09-13" version="1" fragment="single">MKITALIPLAVAVLAFTSAAPVNRRPSPLHPNGKSHKGHSVPLTRNPHFKHNVHAQINKLNKRYPGINILASGTVPLTDVSPDLEYYGTVSIGTPAQDVNLGSSDIWFPSSSCTSCGSHSQFDPSQSSTFKKDGRPWTISYGDGSSASGILGTDVVSVGGVSVKQTIGMATKESSEFNSSPSDGLFGLGFDTIESVSGVKTFMDNAIAAGVLAQPVVSVFLPSVRRNGGVGGEYLFGAIDSTKYTGSLTYVPVTQKGYWQIHISDASVNGASVGQSSEGIIDTGTTLVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SUZ3</accession>
    <name>A0A9P6SUZ3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005266</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002603">
        <property type="protein sequence ID" value="KAG0006495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SUZ3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0006495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="83" mass="9229" checksum="BFC6B5E0A79C0EBC" modified="2023-09-13" version="1" fragment="single">MSNPAKTETFEETIAHVTEQGLLPSTGGHGAAVGTVLEHKHHHEGEHKHHHEGEHHHHHEHKPQDPLESLTQNYGMSGTHQPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SVU9</accession>
    <name>A0A9P6SVU9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Bms1-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_004520</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TRAFAC class translation factor GTPase superfamily. Bms1-like GTPase family. TSR1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002299">
        <property type="protein sequence ID" value="KAG0007552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SVU9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030688">
        <property type="term" value="C:preribosome, small subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034511">
        <property type="term" value="F:U3 snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000479">
        <property type="term" value="P:endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012948">
        <property type="entry name" value="AARP2CN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039761">
        <property type="entry name" value="Bms1/Tsr1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007034">
        <property type="entry name" value="BMS1_TSR1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030387">
        <property type="entry name" value="G_Bms1/Tsr1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12858:SF1">
        <property type="entry name" value="PRE-RRNA-PROCESSING PROTEIN TSR1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12858">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08142">
        <property type="entry name" value="AARP2CN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04950">
        <property type="entry name" value="RIBIOP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22298">
        <property type="entry name" value="Tsr1_G-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00785">
        <property type="entry name" value="AARP2CN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01362">
        <property type="entry name" value="DUF663"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51714">
        <property type="entry name" value="G_BMS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Bms1-type G" evidence="6">
        <location>
            <begin position="86"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="318"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="370"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="30"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="44"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="336"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="410"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="440"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="461"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0007552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="814" mass="92523" checksum="5DDC1D24A409379E" modified="2023-09-13" version="1">MSEQPHQHRSNTKLKQQNKPFKSKHQSKGSLRDKAKGKVERVSVKNQSTRGFSNRTDRRNTARILQQKKREELFRKTKIFDGKDGTPKVVAVVALCADVNSDDAVAKLFASVDQVPANKGTVLMTTDRFKQKLQFVPLQRNYIDIMDAAKVADFILFVMSAVEEVDKFGEMVLSGIQSQGVPSVVATVSNLESTPAKKHSDIKKSLLSFTNHFFPEESKVHALDNANETVNVLRMMANQLPKSVNWRDTHPYMLAESVAFEENPANPSFGTLKVTGYARGTHFQANRLVHLQNFGDFQLEKITSAPIAHKVVHVSNGNGMDAEGTETVLDAPVPGEQDDLAAENEPDLLANEQTWPTEEELMEAEERVKNMDPNEMPEQSFNSTAPKKAIRRVPKGTSNYQAAWIVDSDHESDEDIEDEDDDEDDHMDDDDLPSARNEENSDEEYENLEVENEESTKNEEVYEDELDNEEEARQYAEYLAREKENRDDMEFPDEVEAPTDVPARVRFARYRALESFRTSPWDPYENLPLDYGRIFQFENFRRTKHRVMNQAKEGGVLPGVHITLYIANVPRSVMDSYSDARPFIVFGLLQYEHKMGVINFVVNRNSEYDGVVKAKDPLVLHCGFRRFVVRPIFSQNSRNGKGTNNVHKSERFLQHGRSTVVTVYAPIQFGSLPVVLTKDSGDVNSPILVATGTLMDADPRRIVAKRIILTGHPFKVHKRSATIRFMFFNPDDVWYYKTVELRTKHGRTGHIKESLGTHGYYKAQFDQQISMQDTVMMCLYKRIYPKWGTTLWVNPDAGSSAQQATTTAESMDMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWC1</accession>
    <name>A0A9P6SWC1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_003932</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002073">
        <property type="protein sequence ID" value="KAG0008036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWC1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="61"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="102"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="206"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="282"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="399"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="23"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="67"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="102"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="206"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="231"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="248"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0008036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="492" mass="55259" checksum="ED06D82041F9F936" modified="2023-09-13" version="1">MASMTNAETDTTVLMTSPPISPMSDTTASHLSSPQSTLPLPKQVDTDVMASLDAVLARKAENAQEVTSDYSSGTGSGSDNGHDEDSEVTLTTQEHINALSTFDQQQQSPNLSTEHEGNPQDTPQSDAYLEHAESDASMPPTWEQMGLNNLNDIELREILQNAFNMIQEKEQALGQAAVMGQQLIDANTNLQDKYQRALTQIRHQRMHHPRHLTPPRKIHLTPAPEQTGDVVDGDADGGDENWVDFEPSQSTSQNNSHSSTFSSHHVSFRRGNNHSGTNRIRSRQDIEKMASLEELNAQLQNKVDTITKELKQGRRQAFKRSRKAEKELKAIKDELDRTTIKVVDLEEQNGRLIEASRMIRMRRIMLKNQLPAPGSIPGSTMAAMALEMQGDEMTIQEMLAEDSRIFDELRDRLQSLERRNTALLHQKVEADKKTQLVAQDLADMQKSHDQLSSDLCGYIDLQHAYQEQTAHLKELENTVEEPSAPCRRDFHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SX38</accession>
    <name>A0A9P6SX38_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Amino acid permease/ SLC12A domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_002683</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001670">
        <property type="protein sequence ID" value="KAG0009164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SX38"/>
    <dbReference type="OrthoDB" id="3900342at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015171">
        <property type="term" value="F:amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1740.10:FF:000006">
        <property type="entry name" value="General amino acid permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004840">
        <property type="entry name" value="Amino_acid_permease_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050524">
        <property type="entry name" value="APC_YAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341">
        <property type="entry name" value="AMINO ACID PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341:SF36">
        <property type="entry name" value="PROLINE-SPECIFIC PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00218">
        <property type="entry name" value="AMINO_ACID_PERMEASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="152"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="186"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="235"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="276"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="328"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="373"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="399"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="444"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="477"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="8">
        <location>
            <begin position="42"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0009164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="541" mass="59981" checksum="E28EC396933020D0" modified="2023-09-13" version="1">MEKKEEIGSYDFNIEANQPYENAEFNLAKQHDQLARGLKSRHIQFLALGGAIGTGLFVGSGSILSSTGPASLFLAYLSMTVIVWNVMNNLAEMVVYLPMRGITVPYFVGRFLDPSLAFAVGWNYWYAYAMLIGAEATAAGIVIGYWDLPVSVAVWIAIVLVVMLFLNIIAVSFFGEAEFWFASIKLITICGLIILGIVIFFGGAPNQDGVLGFHYWKTSGAFAEFKAEGSLGRFLGYWHAFISAGFAFITSPELIAIAAGETIDPRRNIPKAARRFVWRLAVFYGISSLLIGILVPSDDKNLLGASNASASPFVIGIQRVGIPVLNHIINAAILTSAWSAGNSFLYSGSRVLYSMSLSGQAPKCFSVTNRRGVPYVAVLFTWCFGALAFLNVSNAGATVFNWFVSISTISGFIAWIVVMITYLRFRRAMEFNNLLNSLPYKTPLQPYSTYFALLIVSLLTITSGFQTFMPFKAKDFIASYITIPVFLLFYLCHKAYFRTPMYIPVDQIDAITGKKEMDELEAMGEERVPKNWLQKVWYWLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXJ8</accession>
    <name>A0A9P6SXJ8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidase S9 prolyl oligopeptidase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_002040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001493">
        <property type="protein sequence ID" value="KAG0009805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXJ8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008474">
        <property type="term" value="F:palmitoyl-(protein) hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12277">
        <property type="entry name" value="ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12277:SF81">
        <property type="entry name" value="PROTEIN ABHD13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase S9 prolyl oligopeptidase catalytic" evidence="1">
        <location>
            <begin position="2"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0009805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="170" mass="19148" checksum="D09A4061DFFDD534" modified="2023-09-13" version="1" fragment="single">TALNYIKEHPVVGETKLIAYGQSIGGAVSIDIVARNEDKFSGLIVENTFLSLPKVIPHVLPMISRVAFLCHQIWNSEQMIQQIARLPVLFLSGRKDELVPPAHMKELHRLLDTTGESVWREFPDGTHNDTCLKPGYFEAIKSFLDGIMGLRRSELSQTSRNPQTRDPQDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXV7</accession>
    <name>A0A9P6SXV7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_001498</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001340">
        <property type="protein sequence ID" value="KAG0010429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXV7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056251">
        <property type="entry name" value="Arm_rpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055496">
        <property type="entry name" value="DUF7068"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004155">
        <property type="entry name" value="PBS_lyase_HEAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46312">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46312:SF2">
        <property type="entry name" value="NUCLEOTIDE-BINDING OLIGOMERIZATION DOMAIN-CONTAINING PROTEIN 2-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23948">
        <property type="entry name" value="ARM_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23238">
        <property type="entry name" value="DUF7068"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13646">
        <property type="entry name" value="HEAT_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05729">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00567">
        <property type="entry name" value="EZ_HEAT"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50837">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NACHT" evidence="3">
        <location>
            <begin position="348"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1239"/>
            <end position="1278"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="226"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1242"/>
            <end position="1266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0010429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1278" mass="143616" checksum="36E7B76E30789295" modified="2023-09-13" version="1">MLKKLENHNNPIVQFLALYAKQGLAYVGNDESLRVSIYRRGRLAIAVAVDIAGGISNVDLEKFVSAYNNIMKMRDFNIRAKFVLESKFKSDERFLQGVCLRLEQIAVTQSVEEIRDGAIKFLHYLSENPPERVRQVAKAILKRSVSHCTGHDTKRHAKTIQCACSVYQAKHFGLPPVWDPSWYTTSSDILLKAVQQGRQNNKNMAEMPAQLVNIKEAVESKASNIMLAVEAGNSNLQARMDILEENMTSKSNLSEVHDALESYYKSSLVIRRVSGDKLDLEQCYINLAVVEARGQREKDKRDLKSQAVAFQRISSRGESTDADIASLMPLESLFDKRKLPNGDEYVPKRISIHRRAGIGKSTLCKKLVHLYQGGRWRDRFDSVLWLPLRQLKSYNYRNIDGLLSERYFSFQSKSKREALSRTMSAQIDAGRVLFILDGLDEIVTSTGEENGDTLKMFLFNLLQKEHVIITTRPSGVGKSILQGMDLELETLGFNPQNVNDYLRIPGVLPQDQIKSVQEFIDQTPVVQGLVNIPVQLDVICFSWGSIPTERKEDITVTSLYQAMVRKLWCKDALRLEKSSSGKILKEAEIHRLQPYQIDKLMDSEIEFLGYLAFKGLEDNHRIEFDEGMLDEAMHSLDQNRARAKKESLPMQLIPWLKETSFLHTSDADLNINPGNFQGTWYFLHLTFQEYFAATWLTRHLQANDEEETSMLMMTTEVTKEFVLKEKYNPRWGGETLVSFFELLQGAPVDLIGGYHHRLLAACLKEGRNQLERQDDKRVKILETQLALWLQFEMTDNNHDYSSTLGSMSYFPEEVLIRSLGQSDASQEYLIRMLERRTSLTQSAVEILLKVLQGSGGPKEIAAMALRKQSTLPESVLQALAGALQDEDAYVRVCAVNALGKQSTLPEFALHALIGALQDKVEIVRCDAAFALEMQTTLPEYVLQALIGALQDKDEDVRRSAASALEEQSTLPESALQALIGALQGEDEDVRCSAAEVLRMWSTLPESALQALIGVLQHENEDVRRNAAYALGTQSTLPESALQALAGALQDKNEDVRVCAAEALGKQSKLPESALQALIGALRDTWEVCDLAAEALGKQSTLSEYVLQSLVDLLQDGVWCVTDIFENQLTLPESVLLALIGALQDKDRVIRDGAAKALEHHVKSTFMAIPNLPPSAIETLHRCFLIEYSSEYSVSLWVQDNEVLFHTSQGPGKVDGLCAEDVAKVVKAFDRAQTQFPMVSAMDDTDSDYSSISDEEEEEEEEEEEEEKEKIANLQTYPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXZ0</accession>
    <name>A0A9P6SXZ0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_001974</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001472">
        <property type="protein sequence ID" value="KAG0009877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXZ0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0009877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="440" mass="50072" checksum="E084BD5371A57119" modified="2023-09-13" version="1" fragment="single">VNYRLSCRTRPILPLLSNLIEAHSSSLKQFQFDGWNNIISVQTFNAVGMCQGLTSLWLSNVILPSTAFKALLDACANIGKVAEEEDGDSIYSISRKKPGGLAELRLEDLSIRDFSAEIFATQTPLSHVEQIHIQEIYGMEPNAQLQLLALCPNIRSLYWRGILFKVKFQVHQWVYYIEAGMWPLLTCLDVLGEEFYDEALSRVISRLPLSLEKLLVRATGFGRMAFNSLISTERHYNHIRELELFACSDVTSSMIQQIMVKMPALESFSANRLCVTDILGTPSETNRNDGDVGDNGHRHGRGREWVCKNLRTLRLCIDMGVASDPTTLEYNERQRQVHLRLSTLQSLEVLELSRNLPYRAGIIKVRKLDHKMNTGLRYLASLKRIRKFLFRPGQSLTTEEIEWMKDTWKSLSTVSRNMNLDQDVNDKLVANLAQHGIAVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SY00</accession>
    <name>A0A9P6SY00_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NADAR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001096</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001245">
        <property type="protein sequence ID" value="KAG0010904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SY00"/>
    <dbReference type="OrthoDB" id="206452at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15457">
        <property type="entry name" value="NADAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.40">
        <property type="entry name" value="YbiA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012816">
        <property type="entry name" value="NADAR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037238">
        <property type="entry name" value="YbiA-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02464">
        <property type="entry name" value="ribofla_fusion"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08719">
        <property type="entry name" value="NADAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143990">
        <property type="entry name" value="YbiA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADAR" evidence="1">
        <location>
            <begin position="7"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0010904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="164" mass="19031" checksum="AB2E9EEB984E05C0" modified="2023-09-13" version="1">MKDTINFYRERDAYGEFSNFYYAPITLHGKEWPTTEHYFQAQKFALEENQDYVEMIRIADGPGKAAKMGRNRAWPLRADWEEVKDDIMRECVLQKFLQHENLAKVLLDTGDRYLNEHTTNDSYWADGGNGRGKNMLGIILMETRVKISAMSPEQIAEAIESARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZV5</accession>
    <name>A0A9P6SZV5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">arginine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">RARS2_2</name>
        <name evidence="13" type="ORF">BGZ80_010484</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>tRNA(Arg) + L-arginine + ATP = L-arginyl-tRNA(Arg) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:20301"/>
            <dbReference type="Rhea" id="RHEA-COMP:9658"/>
            <dbReference type="Rhea" id="RHEA-COMP:9673"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78513"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.19"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.19" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010000733">
        <property type="protein sequence ID" value="KAG0014371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004814">
        <property type="term" value="F:arginine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006420">
        <property type="term" value="P:arginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01389">
        <property type="entry name" value="HMG-box_ROX1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.730.10:FF:000006">
        <property type="entry name" value="Arginyl-tRNA synthetase 2, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008909">
        <property type="entry name" value="DALR_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050342">
        <property type="entry name" value="HMGB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN DSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112:SF22">
        <property type="entry name" value="MITOCHONDRIAL TRANSCRIPTION FACTOR A, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05746">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00836">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="12">
        <location>
            <begin position="755"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="domain" description="HMG box" evidence="12">
        <location>
            <begin position="867"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="domain" description="HMG box" evidence="12">
        <location>
            <begin position="1019"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="10">
        <location>
            <begin position="755"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="10">
        <location>
            <begin position="867"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="10">
        <location>
            <begin position="1019"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="165"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="408"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="701"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="844"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="947"/>
            <end position="1026"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1083"/>
            <end position="1106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1506"/>
            <end position="1529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="50"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="93"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="192"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="228"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="271"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="358"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="427"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="517"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="600"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="633"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="701"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="742"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="947"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="976"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1096"/>
            <end position="1106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="1517"/>
            <end position="1529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0014371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1697" mass="188786" checksum="BE7B31B54DC11CC8" modified="2023-09-13" version="1">MSQYSQPQPQQPQQQQQQQQQQQQHQQHQQQQQQFFLAHNQSPAHLRATQPQQPQQPQQQPQQPQQQPQQQQPAYGSHHSSSHQGAQHFSPAVVSSVSQLPRQQQQPPAQASMVGSGLKQAASLGGVNSVGRGYLDPALSTGPSPSNFGPTNSFGMAASMPNLRSAYGGDDEGGSLIPNDDNPLEAYPLNGNPHSNQANRYQAASRPANNPTTPSRLAHDMRPGASSHILNNNNPTTLSQSQPLSYDQRTATPAMSLKGDVMLGGGGVSGGQHQQSSRHLGQALPQSPYSSYHPAQQSPQQPYPSPHASILSQSQHQHPHQQATPPGQSAITPKESPQLPAPKAAVIVEPEKKKQPKVPKAAAGAKKVGQGKKNSKAQLDNVPSPEISRVDAGSSHAMASAYSNVDSSVAGHGRMYSNPLTPVSLAQHQQQYPSFQQQHQPSPPHLLQNALQQQQQQQQQQQQQQQQQQQQQQQHHQPQHQQHPHHQSQPQVPQQQQQHHHHQPQQQQHQLQHHHQQPQQHPQQPQAQQQQQHHPQQQQQQQQQQQQALRQHQRAESFDNGARPVAQPVAPPAPVPEPAAEKPKGKGRGRKKKVVDEAPIPAPAPPPEPPVVAPMTRPVALPPSSSAPKMSKQLRQQQQQQQQQQQQQQQQQQQQQQQQQLQQLQQQQQLQQLQQQQQMQFQQLQQQQQQQQQQQQQQQQRQQIPSAIQSQTSNQPHQQLQPQQQTQQQQQQYYNATPTAPLPLSQPSLHPSGRPKRPPNAFLVFSSVRRPELQKAFPSHKTAALSKRLGEEWRDMSPERKSLYTSRAKDIKDTFQHNHPEYVYTRRSSKKRAIADVENGSSKKLKGSEYDGNGNYVSSTGLDPNRPRRPMNSYLIFNQEMRHKLLLENANLTVSEISRAIGQRWANMTPEMKREYTEKAASIKAEFLKQNPDYMYSRRSKAEIAASGAARRRGGAPPSVATGKLANNRPGVATPANVNAASGSRSNGVAGNAAGNDVTINGKDVKVRGKKRTKDPDAPKHPIPGFLFFRSGERARIRQMNPNQPIPTVAARMWNEMTPEQREPWLQKAAQDKLRYAEEMQAYSAKKGRKGGSSNEQDRGLDFGDIPKRHRKASHSVFSVVIKRLATTLHGRKVEGKGEREAEGVVVAKSVLDDALLEKCLLLSPETQEYIGHVRKTKDMLLFDPVPLRLIQLTIQNVGKEAAAAAEKEKEKEVERSIAETTTHLGKRNRGSDQVVIVNGSKIQADENAYSSLRRTVLTGFMARFLKESNCQSPVKVITEYTQDTMNPKIKGLYAGLDLVADPSTATLVSGTESYLDTIKEAIRANKDIQAQIDETGAWVVNLTSQRLGNVKLFLKSKTESAAAAAATVDGGEVMEEPTLIVKTLISLAAQFSKYECDRYIWMVPDGRRQFVDQVLYLAKAIFDNNAEQNQDTVEGEEEKGSRKVSTSRIGRKSISSWIESIEILYFGVATGVDIWKAQGELSSGMTGIVEYTNVRMREIVVENRGRPGRGTGYGDDGGDDGGDDDDDEEQVLDEAELTRMATILSTSALAFASVGGKRIRKLNVDMSRIMDGKGNSGVFLQYIQSRLCGIERKSKAKFNLNADLSLIQPYPEALNLCLVIAEWHDTLSALEESLDPYILVSHLFRLAAEIGQANRVLRVKDMEPAVAEARWLIFWAAKQVLEQGLQFLGLEFVERM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0B7</accession>
    <name>A0A9P6T0B7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Prohibitin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">PHB2_1</name>
        <name evidence="8" type="ORF">BGZ80_009625</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the prohibitin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000593">
        <property type="protein sequence ID" value="KAG0015809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0B7"/>
    <dbReference type="OrthoDB" id="275637at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000423">
        <property type="term" value="P:mitophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd03401">
        <property type="entry name" value="SPFH_prohibitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.479.30:FF:000001">
        <property type="entry name" value="Prohibitin 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="entry name" value="Band 7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000163">
        <property type="entry name" value="Prohibitin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23222">
        <property type="entry name" value="PROHIBITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23222:SF1">
        <property type="entry name" value="PROHIBITIN-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00679">
        <property type="entry name" value="PROHIBITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="Band 7/SPFH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Band 7" evidence="7">
        <location>
            <begin position="40"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0015809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="292" mass="32235" checksum="414326A8F6810E43" modified="2023-09-13" version="1">MAQAFNKMGGIFPKGSGKGIVGGAGALIALGALGYGVNASLFNVDGGHRAVKYSRVFGVQKEVYNEGTHFVIPWFETPIIYDVRAKPRNVASLTGTKDLQMVNITVRVLSRPRVNDLAEIYRTLGQDYDERVLPSIINEVSKSVVAQFNASQLITQRDRVSRLVRENLIKRAARFNIVLDDVSIVHMAFSPEFTQAVEAKQIAQQEAQRAAFVVDRAIQEKQSIIVKAEGEARSAELIGEAIKSQPGFIQLRKIEVAREIASIISHSSNRVMLDADTLLLNVSEQKKEETKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0S0</accession>
    <name>A0A9P6T0S0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">glutaminase</fullName>
            <ecNumber evidence="2">3.5.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_009284</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-glutamine + H2O = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="3.5.1.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the glutaminase PdxT/SNO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.2" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010000540">
        <property type="protein sequence ID" value="KAG0016352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0S0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903600">
        <property type="term" value="C:glutaminase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042823">
        <property type="term" value="P:pyridoxal phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008614">
        <property type="term" value="P:pyridoxine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002161">
        <property type="entry name" value="PdxT/SNO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021196">
        <property type="entry name" value="PdxT/SNO_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31559">
        <property type="entry name" value="PYRIDOXAL 5'-PHOSPHATE SYNTHASE SUBUNIT SNO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31559:SF0">
        <property type="entry name" value="PYRIDOXAL 5'-PHOSPHATE SYNTHASE SUBUNIT SNO1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01174">
        <property type="entry name" value="SNO"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005639">
        <property type="entry name" value="Glut_amidoT_SNO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01236">
        <property type="entry name" value="PDXT_SNO_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51130">
        <property type="entry name" value="PDXT_SNO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Nucleophile" evidence="7">
        <location>
            <position position="86"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7">
        <location>
            <position position="172"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7">
        <location>
            <position position="174"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="55"/>
            <end position="57"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="126"/>
            <end position="127"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR005639-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR005639-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0016352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="198" mass="21907" checksum="6FB80D01009D59C0" modified="2023-09-13" version="1">MVQKQQQLRIGVLALQGAFAEHIILLNTLPQVSEAVPIRNAQELSNVDALVIPGGESTTMALIAERSGFWPSLQEFVKTRPTWGTCAGLGISIKRNAFGTQKESFEAGLHVEGLENAEKLFPGVFIRAPVLDEILLPDEVQVVAKLEQDYGKTPKGTIVAVKRGHLFGTAFHPELTRDARIHQFFVDMAREWIMSHPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T134</accession>
    <name>A0A9P6T134_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_009443</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000567">
        <property type="protein sequence ID" value="KAG0016077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T134"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006044">
        <property type="term" value="P:N-acetylglucosamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022036">
        <property type="entry name" value="DUF3605"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35020">
        <property type="entry name" value="N-ACETYLGLUCOSAMINE-INDUCED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35020:SF2">
        <property type="entry name" value="N-ACETYLGLUCOSAMINE-INDUCED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12239">
        <property type="entry name" value="DUF3605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="49"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="148"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0016077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="254" mass="28925" checksum="5658AAF091D315A2" modified="2023-09-13" version="1">MVTDHPTLTSTIFPTMREQQQIESRKKGAQFKGSLNTSIVQKINVTPTQSQTITSNSNSCPSTPSTPSKPLVFKKPTKHQFSWSELTKMIASKDLTPLGRFEQVQEAYQRAIKRRNMKYGSADEYIRQRILHWPPAEKDAETSDGNESSSSCSSASPSSSPTGPVDPLEVRLKKNEFPYSVKPGIEHWLIWSRRPLTDENWIRAYLKERLPGRDFLFFVNPPELRSVPTIFHVQVFTKGEGEVLDEDDIETKVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1M0</accession>
    <name>A0A9P6T1M0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007218</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000366">
        <property type="protein sequence ID" value="KAG0018390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1M0"/>
    <dbReference type="OrthoDB" id="2437318at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="194"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0018390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="231" mass="26023" checksum="B64F5C545A636B29" modified="2023-09-13" version="1">MNHVIRDDQTVLKIHSIGPYFEDVNEIHDNALDCEVVRASGRDAGEYMQEWADRRVPMSKNANVRFNPALVTLHYRPGTVDSFIPGKFSERFMFPGEKSLGFAFRCQCHSVKDLLEVDAKWDVFHTHNLTGPYSDTQSYYEANWIKSVEERAGSEDGESRLEMKEGSDQKRIEELKSELRDLLSNSSTSASIASAYTESPLHPTSDMPTSSSSGSFNTVDENLSKLDMVSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1S2</accession>
    <name>A0A9P6T1S2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BAR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_006629</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000328">
        <property type="protein sequence ID" value="KAG0018871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1S2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015629">
        <property type="term" value="C:actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043332">
        <property type="term" value="C:mating projection tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031097">
        <property type="term" value="C:medial cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990528">
        <property type="term" value="C:Rvs161p-Rvs167p complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051666">
        <property type="term" value="P:actin cortical patch localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097320">
        <property type="term" value="P:plasma membrane tubulation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004148">
        <property type="entry name" value="BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046982">
        <property type="entry name" value="BIN3/RVS161-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47174">
        <property type="entry name" value="BRIDGING INTEGRATOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47174:SF1">
        <property type="entry name" value="REDUCED VIABILITY UPON STARVATION PROTEIN 167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03114">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00721">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51021">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BAR" evidence="2">
        <location>
            <begin position="1"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="164"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0018871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="288" mass="32409" checksum="E3EDE68311FC9B32" modified="2023-09-13" version="1" fragment="single">MVQTKDAEFIELNKKFTTCEKVTASLLTEVCKYRDNITTMLNSQAEFGIILAEIYDPSLGMPPGEVTPRRTQTAPESMQAVNDFQAVMRETRDILLPEIDKLEFQVVQPLTDMQTNMKLIRKTITKRDHKLIDYDRYRISLQKLRDKKEKTLSDERQIYKAGGSASPDPSALSASPAPSSPKPWQASAVPGAAPAAKPWQTGAGVKPWQTGGAGAGLNSLLKEELPGFFYYKTHLMEPIFHIFYYLQLRIYRIMLDRMGPISGSGYFDLSMDVQQGYEARKQDTLATV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T305</accession>
    <name>A0A9P6T305_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_002902</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000174">
        <property type="protein sequence ID" value="KAG0021187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007265">
        <property type="term" value="P:Ras protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06224">
        <property type="entry name" value="REM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.840.10">
        <property type="entry name" value="Ras guanine-nucleotide exchange factors catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.870.10">
        <property type="entry name" value="Son of sevenless (SoS) protein Chain: S domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008937">
        <property type="entry name" value="Ras-like_GEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000651">
        <property type="entry name" value="Ras-like_Gua-exchang_fac_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023578">
        <property type="entry name" value="Ras_GEF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001895">
        <property type="entry name" value="RASGEF_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036964">
        <property type="entry name" value="RASGEF_cat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113">
        <property type="entry name" value="GUANINE NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113:SF363">
        <property type="entry name" value="PROTEIN SON OF SEVENLESS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00617">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00618">
        <property type="entry name" value="RasGEF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00147">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00229">
        <property type="entry name" value="RasGEFN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48366">
        <property type="entry name" value="Ras GEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50009">
        <property type="entry name" value="RASGEF_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50212">
        <property type="entry name" value="RASGEF_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-terminal Ras-GEF" evidence="5">
        <location>
            <begin position="572"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-GEF" evidence="4">
        <location>
            <begin position="1601"/>
            <end position="1900"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="110"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="249"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="301"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="346"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="426"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="456"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="709"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="824"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1048"/>
            <end position="1086"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1278"/>
            <end position="1303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1328"/>
            <end position="1372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1469"/>
            <end position="1493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1546"/>
            <end position="1575"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1680"/>
            <end position="1699"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1818"/>
            <end position="1901"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="110"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="278"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="308"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="346"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="426"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="483"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="510"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="710"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="770"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="830"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1060"/>
            <end position="1076"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1346"/>
            <end position="1357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="1553"/>
            <end position="1563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1683"/>
            <end position="1699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1820"/>
            <end position="1831"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1832"/>
            <end position="1857"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1860"/>
            <end position="1870"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1871"/>
            <end position="1901"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0021187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="2120" mass="232479" checksum="BD20D6494ACF69A6" modified="2023-09-13" version="1">MSQDSARAGVAGKMEAISVTATTTPSMEDTPLIVPPSVTTSVITQPNVPVTAGLLTESVQATAKATELLIPTEMDTPIELTTELLTISCASSLAVNTTTSVTTRANSTQLSFGTDVNPFNDSEQKDISATPTTSPDAKEDMNPTDNNDSNQGEENDQAYVNYHVNQTEIVNDEDSVAQTRIVLPKFKSESHSRKSISLPPLKTTPLISNATQTTSSISTTPATTSVTTPTPIATVKTTMTATAAIVSPNHGNEVVPTPPPSAQEAPKSRIKNEGNIPEGNNSQNGNGFWNGGVNADFNGYQNDPHVGYNSTHPLSTEASSPTDYFPSPYVLPPIPSFTEMGLKFDKSRTNSAESTEKQALDASANRHDHDDEGRSSTPRQCHQSQLGNFQFEDEIAPDYDPSIFDQIQSDENETYILWSSPLDSSVGVSPSSAADSVPATPQSNKQVVIPSTVATYENVHNPPSSPEPSSSSAVKRWSAGEAFKSKDKGRDSLDGERAHGQASEGVASEVSKSNGHTMETTAGQGLPLSPSFPKPLERLSGTISIKRPLSSVASPSSKSATTNAVVSSNPTEERVIMAATVEKLVEKLTSDIDYTFLTDFFLIYRLFISPLALLKLLVARFHWALTEDTPQRQVVRVRTFVTMRHWLLNYFEYDFMSSRALRRTHVKSLRELADHPIVRSSVRDKRIVKELRKLYHLKRKNQYREMAQMTLEQPSTRQTNEPSSRRSFQGRRATNSEWVECTNATSSKRSSMDTSEVRNTRHRLAGPTLTVDSRPSRSGNEGSPDDESTENESGLSSADGHSDDENMYVEEVHFVANGDRQHYQELSDDKTEDTDLDDDSEPTDALSNSGHLPSPAFSAESIKSKKVEPDYNSQGVIDNGADASYSTSSQSHPGFPHSPDASDHAAHSQRSKTIPRTLDARSFSRPLFCGDDTSSQYALSPPDSPRLLESYINPPPPSIVSTEKKKTWSHYMVATVEQLSKVKKALLPKPSSSVQDLRHNPTSASSASHLVRVASVGNGRPRGSSQDTDSMSNTHAAIGKHWNNEEQLYPGSGLVKPLHSPTTANASVATNSAASSLDGRRSREVTDQVIHHQSIVSSEWLSDEEEYQSESANKIVERTQTCGDSNKADRRSFPRQMGDEAVGYVMATQNERRLQQSSPCKSRRRSLPLDSLMAATGTARRNRQSLELNEQRVGQTAQEEEEGYMGPQTAGFISNSRALRRTTQKRDSRASWMTFSSSNSSVFGAVLSQGHLSPSQTIRERNDAGNVDRFMERLYQSQDPNEVSGASEAGHGGSEIPRRNGMCRKSTGAIHEKSARDGLARSSLNSDSIVSTVGGTSGKAVSRANLKQEQRGNESDNSKPGMSARRSHTLAQHPHRQTVPIMHLHYHHFLHHRQSESLLQGFPTQRRHSVEVQSLGAWRTSQQKERKNSCDITAPVPVSGTLLEGAAYAAALQETQRQLRLLISQENQNPKNSIQAPPVLPHLPGRPMGQARARPLASISGNSALQAYQPSNKISPISKLNQAVRGGGAVGPGGAYKIHSPIYPSSQGASYTQHHHHYHHSHSHSYEDSYDQQRSPMNPRFQNVISSTPRPRPTSIVLQHRSEEIAEQLCLIEREQLNQVHWYELVNAGWKKKSQEEPSSSSDIFTEDSIANTSTECGDAEASNIQHPADVNVMKESDLDHQPASTLSHRASPSPLNRSHTVKSHMQRFTHQSHTSDSPNVTQLVDRFNLMCRWVTSEILKTTDLEQRVKTCYNHSNFSSLTQIMVGLQVFEVSRLHRTWARVRSQEKKIMHELMEFTSMSRNWKHIRNAMKSIADEWGSASPSATTTVSSNQDGSTSTVSSAFPSNGKQQSLNLFSKMTGRDKDKEKHQQQTSQVNNSSSVHSKYISHNHSSSFGKSSGHSVTITSASVSGSVSGHHKTSSGQGFPSLVSSFTKEKTLLQTSSEKDKDANKTLGGCIPLLAVYLSDLLYNTELPSYIEPKASLSYDVSATNMVTTMPEPARLSAEISHHLPSPPQSAATTPYKAAGYHINSSCPTAAVASIQRPLLMVNMHKHRTTATIIKRILTFRTMANRYPFEKDTSVYNQLMAIEAPDQLELERLSDLCEERASSSGLASPVFAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T347</accession>
    <name>A0A9P6T347_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Bromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_004248</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000219">
        <property type="protein sequence ID" value="KAG0020397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T347"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd04369">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45926">
        <property type="entry name" value="OSJNBA0053K19.4 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bromo" evidence="4">
        <location>
            <begin position="449"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="122"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="344"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="126"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="165"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="195"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="217"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="235"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="350"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0020397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="557" mass="60077" checksum="56B8B058DDF5F78B" modified="2023-09-13" version="1">MTASSKPSPQASSGAASPSIPSGSQPGSWSGIRPVADNAPAVTTAEAQNNRPIVSSVISLPVLFTSTTTGHEDTAAAAASESAVAPNSSAFTSSTLVNDSTGFKIRIPRDLPNIPPAFRKRGAIRSQPSVSSNARFSPVHPSAARPRSTESEPLYQTKLVVSPREPVDNGKRTHNDMLSEDSQAPRNYLMLEPRVGSEKKAKTIKPETDTPEPPKMSRSSSANSLPIQDNVPVRDSTTNPTPELTTHIIPPETQPSTSAYTIKDNIKQEEPTDIPMASVSRLKRQRSRTKSEPDSPTPTPVRFPTPTSIGRGIAGDIEEAPQDLESTPMESVVLSAPVAPLEPNDISVASADSNSTPVAEAGSSSASSQPIIETPPNMPETTPIKPEEIETSTKEQLMLRENSTPPLAHSTVNSTPDPNEPTLKPIELVRLGTTVLDRLLSNPVCKNFVNRVPDNVANYHAVIKKPMDLMTIEHKLWKSLVTHQSALDSSLAPGAIIAAKSYNSSSEGYVNLQEFEKDLQRIYRNAIYFNPPQQVIYKEAQSYEVLYKGLLNALREQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3B1</accession>
    <name>A0A9P6T3B1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">WD40 repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_002244</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000155">
        <property type="protein sequence ID" value="KAG0021505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990234">
        <property type="term" value="C:transferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.80">
        <property type="entry name" value="E3 ubiquitin-protein ligase SopA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024977">
        <property type="entry name" value="Apc4-like_WD40_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056251">
        <property type="entry name" value="Arm_rpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847:SF637">
        <property type="entry name" value="WD REPEAT DOMAIN 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12894">
        <property type="entry name" value="ANAPC4_WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23948">
        <property type="entry name" value="ARM_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="16"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141571">
        <property type="entry name" value="Pentapeptide repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Arm-like repeat" evidence="6">
        <location>
            <begin position="237"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="domain" description="Anaphase-promoting complex subunit 4-like WD40" evidence="5">
        <location>
            <begin position="1192"/>
            <end position="1275"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1223"/>
            <end position="1264"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1265"/>
            <end position="1307"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1308"/>
            <end position="1349"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1350"/>
            <end position="1391"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1392"/>
            <end position="1433"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1434"/>
            <end position="1475"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1476"/>
            <end position="1517"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1518"/>
            <end position="1559"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1560"/>
            <end position="1601"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1602"/>
            <end position="1643"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1644"/>
            <end position="1683"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1766"/>
            <end position="1807"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1808"/>
            <end position="1843"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="119"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="144"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF23948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0021505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1897" mass="210102" checksum="1021C054205CB85C" modified="2023-09-13" version="1">MLRNIFSSRKSKLTLEGTLELASNHLDSAHKTSDPTKSLRHCRNAKSAIKDAEKIFAAKKVEDPALHNSIANLYHEHGKLLDGLGYYSKAKRSHIKAKEWGYVYTVSQKTESSLPGNESNSSHGSLSPVSLSDLSGIEAEKSKNTSGPDTAQSSLQSQSQNEILVVQKSIEAVKPPQAIFRQDVSPPVAKYTLPEDDERITSTPQLAYCLSLLDPSLISKEGLDNIEFVWSQAKINNVDEQARLKTMGTDVVKAFVRDELKKPDVVAEVVCLAAVLERDDFRKVLQAFVDGIEQSVLLEVHLLDGLAQLMRNAVQGCFDADDLVKILRLLNNRLKDTHKQSAEHTYRLAMTISRVLDSMVDSQVKGLSREQLHEPLSDYLKGLQGSSDPYMVYQAVYAFQALQYVPDDETILQSMLRRTGKVVQGISGVVSAVKALDLNGFIEGLQHIQGGLAAVGSAIEIAHDAFSNAKALVESGQGFLESLKEGLSFTRKSAWYPALRGLDRLLQEGQFAEVERLIREAPCRLDPAFQWGVCQRLGELAVNTAWDANTRKGALTFLADQLAGSTDSIVSSESKILMEELRTDGDAEKQMLYETSRKERSVPYPMTVTLPPQKSPLLGCVQNKPDVETPLRQLKRERLKERGGDVYISPRAKLNPRATDDFDLTSKVQGFIDSDRKVFLILGDSGAGKSTFNRALEISLWDKYEKTTGRIPLFIHLPVIDKPEQDLIAKQLHKFDFTEKQIRELKAYREFIVICDGYDESQQTRNLYMSNQLNQPGGWRAQMVISCRSEYTGVDYKDRFQPTDRNKIGGSELFQEATIVPFNKDQIQDYINQYVALMKPSWDSKDYLRAINQIPNLQGLVENPFLLKLALDVLPRLFNTKSDFKTARVTRIGLYDEFIAQWIERSKIRLGDMELSAFDKEAFKILSQSGFKQHGITYLKELTTAIYDHHGGNPVINYSEYQDQKTWKEAFFNKKDGKHLLREAIPLIRNGDQCRFIHKSLVEYGLALAVFDPNSFTENTEPAPIVSRRGSTSSALSFEISESTDKISPLAIEQPLLDSPLGRKHFVSETAVLQFLVDRAQQQIVFKDQLLAVIERSKTDKSARVAAANAITVLVKAGVQFNGADLRGIKVPGADLSYGAFDSVHLEGADLRKANLRSIWLRDANLDGAQMAGVHFGELPFLQEDSAVNCCAYSPNGEIFAAGLSNGDICLYTTSNWERIQIMRGQTNGVRCLVFSATGGQVATGNEDKTVRLWDIETGNCVHTLQGHSNRIDTVLYSPKGDQVASAGEDDETLWLWNVNTGACVHALKDHFMGIRSIAYSPSGDQIASAGWDEAVRLWDVDTGNCIRIMRGHNGFILKIEYSPRGDLIASASDDSTVRLWDVNTGNCIHNFQGHTYGATSVAYSPKGGQIVSGGGDNTLRLWDVDTGECIHTLQGHHDTIKSVMYSPRGDQIVSRSDDKTLRVWDADSGNCIHILQGHTGIVSSVVYSPRGDQIASGSYDKTVRLWDVNSGDCVHTQQGHTHRIRSVVCSPKGDRIASAGDDCTVRLWDVNTGGCVHILQEHTGSVNLIVYSPTGDQIASASSDQTVRLWNSDTGICVHILQGHDRVVTNIAYSPKGDRIASGSDDNTLRLWDAETGSCLHILQGHMSHITSVVYLSKDQISSSDSYVMRLWDVDTGDCVRAFQAGSKPTLYVVEDPADVDHIIPGDINNRVRLWNADTGHGFYTLGSYIKSVEYSPRGDQIAYASVKDNVLLLDVETGNVVHSLQGHTDSVWHIVYSLKGDMIASGSNDGTVRVWSTETGQCLVTISGFSQNIKSIAWRNSVNGHYLVTGGQDKSVRYWQIINEQDGYNALMCWSSLYEKLTVSGASFNNVQGLGDVNLKILSQRGALITTSLSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3D8</accession>
    <name>A0A9P6T3D8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Meiotically up-regulated protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_001376</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000131">
        <property type="protein sequence ID" value="KAG0021944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3D8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.110:FF:000046">
        <property type="entry name" value="dnaJ homolog subfamily C member 21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051964">
        <property type="entry name" value="Chaperone_stress_response"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003604">
        <property type="entry name" value="Matrin/U1-like-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022755">
        <property type="entry name" value="Znf_C2H2_jaz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054076">
        <property type="entry name" value="ZUO1-like_ZHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44029">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44029:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12171">
        <property type="entry name" value="zf-C2H2_jaz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21884">
        <property type="entry name" value="ZUO1-like_ZHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00451">
        <property type="entry name" value="ZnF_U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="J" evidence="7">
        <location>
            <begin position="4"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="314"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="146"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="290"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="351"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="461"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="582"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="251"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="296"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="369"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="394"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="425"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="461"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="527"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="582"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="596"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="616"/>
            <end position="626"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0021944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="626" mass="70612" checksum="B8C7A8699FCB5A17" modified="2023-09-13" version="1">MRTCHYVVLGIEKNASDSDIKKAYRKKALEWHPDKNHHRVEEATKQFAYIAEAYEVLSDPQERAWYDSHRDAILRGDDKSEQSESAAGTAAADLMKFFSSSVYKGFQDDNAVSRLHKGDGKWKGDAGFFAVYRNLFAKLAEEEEEAVANDRNEDSTGGANVHYPSFGSSTTPYDDNSDSDVKQFYNAWLTFSSQKNFSWCDKYRLSEAPDRRVRRAMEKENKKFRDAARKEFNDTVLSLAAYVRKRDPRFLAFQEQQKQKQKQTQADLKAKMEKEKELLRAKVEQFQEQEWTRVQEEEEEVSGSENEDEFDQEYECIICDKSFKSERQWKNHERSKRHLKAVEDIRLEMLHEENQLMGGQSPLSKDQEVMEDNDDDDEAEEIEMPSTKSKGDNNEEEEEEEEGLSEEEPEEPIEVVTSIYAELKSKKKNKKKKVMTTDLDFDEAEIGEMDKDGLADLLGSVRLSSSSSPLSRSRTSTPSNRRSRTQKSGTNWGGDSDNEQDGTPISTAPASRAESPDGLGGGGAGGKAKKLSGKEKKKARSERAAQKLADTGSSLKCRICSEDFESKNQLFAHIKETGHAVATAAAASTGSNTPTRMTSSVETSGFSSDEEQQGRGKGKKGRGKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3M5</accession>
    <name>A0A9P6T3M5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_011231</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000088">
        <property type="protein sequence ID" value="KAG0022751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3M5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101447">
        <property type="entry name" value="Formin homology 2 domain (FH2 domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="19"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0022751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="199" mass="22420" checksum="E840285D6F07D678" modified="2023-09-13" version="1">MRLIVPHFLQQLQLNMSQPVTPTPTVTSSPAMPPPPPPPPPAPATANATSSSDESDRIDLNESYRDVGAIENVKAIGASYADFASAVLERWKEVSSNMHKIENMLVANLENRNFRSREYETVYNHLVQQEKALSKQLQVLYPARNPHIDQVVALIETQWHLPPSELRPIHPGQLIFSRYNYCPPKTPLQKYSTSFPTQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3S0</accession>
    <name>A0A9P6T3S0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_010566</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000075">
        <property type="protein sequence ID" value="KAG0023026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3S0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="38"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="173"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0023026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="189" mass="20385" checksum="F621F75C3EE9EE1A" modified="2023-09-13" version="1">MSEKSLSTSSTAGTALLDSRKGTVKPGMQYTIAGGAGLSSSSPLAQSPAAGSDPMAPVSNPAMPPITPPKKNRLFGVKSKASKKANRVSVTGSQLSAGKKRLPPGVVRKDLMTKTEESLDEVFPWTCIEHTAGQESGWVMLEPVQDGAVGWVKIDKLEEEIKRLAEAEQARKQQQQQQQQQQQLMEREQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3U4</accession>
    <name>A0A9P6T3U4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Vacuolar protein sorting-associated protein 74</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_010227</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GOLPH3/VPS74 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000069">
        <property type="protein sequence ID" value="KAG0023167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3U4"/>
    <dbReference type="OrthoDB" id="2189106at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031985">
        <property type="term" value="C:Golgi cisterna"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070273">
        <property type="term" value="F:phosphatidylinositol-4-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043001">
        <property type="term" value="P:Golgi to plasma membrane protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048194">
        <property type="term" value="P:Golgi vesicle budding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3630.10:FF:000004">
        <property type="entry name" value="Probable VPS74-protein involved in protein-vacuolar targeting"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3630.10">
        <property type="entry name" value="yeast vps74-n-term truncation variant domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008628">
        <property type="entry name" value="GPP34-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038261">
        <property type="entry name" value="GPP34-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12704:SF2">
        <property type="entry name" value="GOLGI PHOSPHOPROTEIN 3 HOMOLOG SAURON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12704">
        <property type="entry name" value="TRANS-GOLGI PROTEIN GMX33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05719">
        <property type="entry name" value="GPP34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="4" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="17"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0023167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="318" mass="35539" checksum="BAED713EC59974F8" modified="2023-09-13" version="1">MASTSGLSRRRGAGVGASESANNSSTQSSDSDAKVVSDPRDLQMEDENKTQPRFTLMEEVLLLGLKDKQGYLSFWNDNISYTLRGCILMELAFRHRIAMVKDPNRRKYPLADRYIEVISQKLTGEVLLDEALKMIGSTEERMSVGQWIDLMSGETWNVMKIGFQLKQVRERLAKGLVDKGVLRTEKRNFLIFDMATHPVTDSAVKEEVIKRACTALISRSAGSSPNLAEQNSPVAYQQLRTVAMVCAAYAGNVLENALMYLNHEMRERAYNKVDELLNDYSVFPFGSNASKSEVAGKDLQMEVVAAVLNVFTKMDSIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3U9</accession>
    <name>A0A9P6T3U9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_010105</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000067">
        <property type="protein sequence ID" value="KAG0023200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3U9"/>
    <dbReference type="OrthoDB" id="10018191at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="297"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="326"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="253"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="212"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="253"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0023200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="376" mass="41151" checksum="69B9FC653474CBAA" modified="2023-09-13" version="1">MYNSYTFGSQQGPASLRRETTEDISKMYTTLYDMEDPIQQQEYALLQSQRQQESQAYFDTLMSPALPASPASDCFSSSSSSSSSSAYPSPIAALVRSMDPDEADELVESFNITIEDLLSGDPLSFDYSKGLDLDSAADFDLFEPQEQVGHIMHSHCSFTSGGPIRSSSMSPNISCAPYATVYNQHQMEHIHNTASSPLHFQQFHHLHLHPEMPNSPASTSTASPSPSPCPSPSVSSTPCMSPLALSTSTFASPSTTAATTTSSSPSSAIPNTEGMTVIKNDDGSIMVYNPTTESMTFRCELCPGDSFGRIHDLKRHQASKHQATTWPCEFCHRPFARRDALLRHYTVKSQRDDGLHPASNEKEKLLAARAKAKLIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T412</accession>
    <name>A0A9P6T412_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_010517</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000074">
        <property type="protein sequence ID" value="KAG0023056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T412"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0023056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="471" mass="54842" checksum="1D5230E729435E79" modified="2023-09-13" version="1">MRSYQQRHERAPRDRKKSRTEGTRKHRTYGEDLKKQDTGTSHPSKGLDSKSGSTCPLTLSGVIDESQRPYYFAFNKLTNLHRFEVFWVTENKCDWETLDRVLATLLLGNHNGISAAGKREVGEKSKEDNKPLNQIREFSLQTQSRLDVRFQKILCYFKNLEVLELRANYFQCHTWLSNWDPKLCRNLKVLRMLWNENSANLEDLGRLTGLEELRMAANNPNQFQWIVDTKMKLSRCQEVRTKGPDSTNGVCTVASAKKASRVSYDDNHPLHHCLPKLKKLGCYITYADCQLLFNNITEAFGDQIEELVLWASSWRPAIRFEHPFRYLSRLALRGEYLVRFDYKSLVQHCPMVELLALQHTRYSRYADVRPDDNAIVAALVDLKLLRCLYLEGTWYLNNEHFLKLAQGSKSLYKIGVYRCDAVTLATLSKADEILCSRYSKYPLKPKGVHRIPNFNGDDFSWSVTFFWHEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T426</accession>
    <name>A0A9P6T426_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">GATS protein-like 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">GATSL3_2</name>
        <name evidence="5" type="ORF">BGZ80_010298</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000070">
        <property type="protein sequence ID" value="KAG0023141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T426"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046394">
        <property type="term" value="P:carboxylic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2130.10">
        <property type="entry name" value="VC0802-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027795">
        <property type="entry name" value="CASTOR_ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051719">
        <property type="entry name" value="CASTOR_mTORC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31131:SF6">
        <property type="entry name" value="CASTOR ACT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31131">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13840">
        <property type="entry name" value="ACT_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="ACT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040408244" evidence="3">
        <location>
            <begin position="22"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="281"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="CASTOR ACT" evidence="4">
        <location>
            <begin position="349"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="460"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="68"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="486"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0023141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="531" mass="56743" checksum="6842DB4B72F751E6" modified="2023-09-13" version="1">MPAMVLIYLLASILLLSGVHAQDSTTPTNLNATVSLTPTSTGGSSGTATPTTATITTSASSISVSLSTSVSPSSSGTTPPAESTPVTYPPGTVNCFSMPYCSESEECFVLEDGLVCMDKVINSGYILSRNDSGVPSVPSWSGKRSGLNSNCTLFQMPKSADKPGLALMVYDLIQYTIPPDLLISRYDTSRTNWYTLFSNCETDLACVMGKCLPRPTLGQSCTTSWQCNARALGLNENNSPIPTANVTGVRCEYENGDKSINTTCQLLHRDVVDSSSGGFSAWHVIVPVVVILILAYFGTMFYQRRMKDQKARKWSRISDESDKEVSLILDETHISGFPEDTLDVCNVIWRAVQIEPGESGLDALEVVSQVSKPLADINVSIMQISTYDADFTLMPECDLTRALECLSNTFPIGNNPLEDAELQPSDLQSWEESFPTCPTKINSLQDALLVGAATTRGRKSSVMSTMDNCEDEKLRNGRGDSGVGSEATSGTNSGLNSGHGSHVLGTTIAGLDPSLISSLSIKDGTKATRGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T4G3</accession>
    <name>A0A9P6T4G3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Defect at low temperature protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">DLT1</name>
        <name evidence="9" type="ORF">BGZ80_005245</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 7">Required for growth under high-pressure and low-temperature conditions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the DLT1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000026">
        <property type="protein sequence ID" value="KAG0024207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T4G3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038869">
        <property type="entry name" value="DLT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40021">
        <property type="entry name" value="DEFECT AT LOW TEMPERATURE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40021:SF1">
        <property type="entry name" value="DEFECT AT LOW TEMPERATURE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="7"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="218"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="314"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="219"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="234"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="323"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0024207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="421" mass="47367" checksum="D7482A3CFFA36CCA" modified="2023-09-13" version="1">MPLTRSSYLYVSSLFFLVAVTGICVIASAYDVIFQIFHPSFSGDPPNYKNLAVFVGSYVLLGLLATICGFSRYVTVKLARQAIPKAYMPITEEDLPTSVYEFVQSELDRVARLAKQAGPLLEESGQPGWGKPESSLEDTHFKTFMASTPHFIEKAAVARSPDLARPPNMSISAYVHMLMDQKLVTRDIGLEYIAGYEQARFGGTRYDPLPVTMTPLHNQSHRHQRTSGRHHRMSSISNTRYPSNMSAPTADGNASNLARNGMEVIEEEYYIRFMKTLSYLLQELGWDQEAYEEECREQERLQQRDYDAMLEQEKNRQDYGSDCNFNSTSSRNAGEKPRVSSQARNSRLSNESYYIVDESELHPYNYSHGRRDNDGAVGKIAVSGVGGEAESASRTKRYFSRNSNLSTTILTMRTTSTKSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T4G7</accession>
    <name>A0A9P6T4G7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">tRNA A64-2'-O-ribosylphosphate transferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_010516</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000074">
        <property type="protein sequence ID" value="KAG0023055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T4G7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043399">
        <property type="term" value="F:tRNA adenosine(64)-2'-O-ribosylphosphate transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019988">
        <property type="term" value="P:charged-tRNA amino acid modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007306">
        <property type="entry name" value="Rit1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033421">
        <property type="entry name" value="Rit1_DUSP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033449">
        <property type="entry name" value="Rit1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31811">
        <property type="entry name" value="TRNA A64-2'-O-RIBOSYLPHOSPHATE TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31811:SF0">
        <property type="entry name" value="TRNA A64-2'-O-RIBOSYLPHOSPHATE TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04179">
        <property type="entry name" value="Init_tRNA_PT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17184">
        <property type="entry name" value="Rit1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rit1 N-terminal" evidence="3">
        <location>
            <begin position="19"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="domain" description="Rit1 DUSP-like" evidence="2">
        <location>
            <begin position="484"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0023055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="616" mass="69188" checksum="871EB43B4904A78F" modified="2023-09-13" version="1">MTKIEPTQISSHGRSRDDMRRDAKNLMNRLKSIKADAAFVSEISDLLPQFPVFANERCGTWYVHPSKIQKPGVYFKSTDGHTGRWDFNLRRYNPHLITAIIENGGCIIVDSTRKGKRVPDALSKTIPIWCATINTAIRKSALQDHERQQQSSSQSGRKDSSPLGADAAEPTSLPSLKGDKSSKGTEAHLPVPSLDSERWDTRYHSLPSLISRSEHAQIAEKIDAFAEKLMRFTDITPLTTRLSKPIRPIWLTPQSVLFKDDMPDYSRVNFLPVICLSASRVVPEGMEECDGYLYVQGSGDDEEMWSEGLTPDLFWKNEDYLLEEGITSAECERRAREIVREAKKVQLECSHQQLDITVNRQEDGTSKEKISNGQLLFTPSMELCSEIKPSPFWIGNNASGRIPDCWQSGFDMVINCAAEIQRDSFFEWTEGSQVVLQLGGTGVGGTPASLCIVQRHQWETATSASSSSDLTITTDTTSNKEYYYLHLPIAEGKKGQHQLLEMIPIAIKAVESFYASRTMREGAETMNPRILIHCQQGMDRSVGITLAILVSCFEEGTGRYCGANTNQRTATKETIQRRLFQIMSHRLAARPSRATLKMINTYFMSPTDPLPAKYKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T4I6</accession>
    <name>A0A9P6T4I6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">YmL10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">MRPL10</name>
        <name evidence="7" type="ORF">BGZ80_004279</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000022">
        <property type="protein sequence ID" value="KAG0024317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T4I6"/>
    <dbReference type="OrthoDB" id="361383at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.100.10.10:FF:000011">
        <property type="entry name" value="50S ribosomal subunit protein L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.100.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01341">
        <property type="entry name" value="Ribosomal_uL15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030878">
        <property type="entry name" value="Ribosomal_uL15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021131">
        <property type="entry name" value="Ribosomal_uL15/eL18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036227">
        <property type="entry name" value="Ribosomal_uL15/eL18_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005749">
        <property type="entry name" value="Ribosomal_uL15_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001196">
        <property type="entry name" value="Ribosomal_uL15_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01071">
        <property type="entry name" value="rplO_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12934">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12934:SF11">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL15M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00828">
        <property type="entry name" value="Ribosomal_L27A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52080">
        <property type="entry name" value="Ribosomal proteins L15p and L18e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00475">
        <property type="entry name" value="RIBOSOMAL_L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL15/eL18" evidence="6">
        <location>
            <begin position="118"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="40"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="40"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0024317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="250" mass="27421" checksum="A05396219F3919B7" modified="2023-09-13" version="1">MSMNRLAARLSGLCLYPTRATVSTSSSFVAKYSTAAPTSRVDLSNLSDNPGSKSQRIRVGRGQGSGKGNTAARGHKGQKARAGNNGQPKPGFEGGQTRLIDRLPKRGFKNPEHKDFQPLNLDRLQYWIESGRIDPTQTITMKHLLDSRCIHNIEDGVKLLGDGKADFKTPINIEVSRASKSAIKAIEACGGKITSVYYNKLGLRALTKPEKFEELPRFARPMKKKDIAFYSDEANRGYLAGKAEVVGMDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MCA6</accession>
    <name>A0A9P6MCA6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_009163</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010005268">
        <property type="protein sequence ID" value="KAF9991383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MCA6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9991383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="120" mass="12454" checksum="9FCA49479E9B641F" modified="2023-09-13" version="1" fragment="single">KWTYETKTYETFEEVEEVEEVVDETKAQEIITQQEREVEEKSTTVTETTTTTEEIVVTEEGEVSKPADSKGSLFGRLVSSTKAAAGAVGDAVGTAASGAAGAVVHGASEAVDAAGSAAHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MCW5</accession>
    <name>A0A9P6MCW5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">WD40 repeat-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_008597</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004701">
        <property type="protein sequence ID" value="KAF9992343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MCW5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848:SF8">
        <property type="entry name" value="F-BOX AND WD REPEAT DOMAIN CONTAINING 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="43"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="85"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="127"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9992343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="183" mass="19532" checksum="89381550EFE70B9F" modified="2023-09-13" version="1" fragment="single">LKGHSSEVNSLSFSATGDRVASGSFDSTVRLWDVDTGECVHTFQGHSGSVWSVAYSLKGDRIASGSDDRTVRLWGVDAGECVHILQGHDDTVWSVAYSPKGDRITSGSYDSTVRVWDVDTGECVHTLQGHTEWVQCIAYSPKGNQIASGAVGGQDSTLRLWDADTGECLHILQGHSGGVTSFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MD41</accession>
    <name>A0A9P6MD41_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Retrotransposon gag domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008460</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004595">
        <property type="protein sequence ID" value="KAF9992642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MD41"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005162">
        <property type="entry name" value="Retrotrans_gag_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03732">
        <property type="entry name" value="Retrotrans_gag"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Retrotransposon gag" evidence="1">
        <location>
            <begin position="167"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9992642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="255" mass="28990" checksum="56C2688CD3250859" modified="2023-09-13" version="1" fragment="single">MSDQDAFMSHQQTLHQQQSTLLAEMDSHLTNPTFDPQQLLGTLRNMLSVMNTRSKSLSAHYEQASHLMSISNAVAIVQVQNQEALQQQTVMLNTMQSMVHELLEKPAVPVAPENHNHRRVHIPHPFTPAFNGDPKVLSFRAFKAKLSVVFQCFDSAFDSDNHCVNYALSCMTGPPLEHYAPIFNHEIQDEEDILENYENFINAVEAAYSDHLSVQEAEDKIRFLKQHGSMQEYISEFSTLQGQVRYNQAALVSQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MF13</accession>
    <name>A0A9P6MF13_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_007414</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003794">
        <property type="protein sequence ID" value="KAF9995789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MF13"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9995789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="62" mass="7376" checksum="E15E11BE4124EA98" modified="2023-09-13" version="1" fragment="single">DSLIQRYTIDYACNITRKLFTDKEWTEVQTYNEWDFQTSGKTLPVILNEFSPRSKKARTLQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MFP4</accession>
    <name>A0A9P6MFP4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_006954</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003481">
        <property type="protein sequence ID" value="KAF9997636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MFP4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9997636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="101" mass="11407" checksum="8E54C471D01117A4" modified="2023-09-13" version="1" fragment="single">ESEDVEKALKAYKDERYPIGKSAVETSASVFKGIQQGLVARLVRAILRRMPRWILFAICARAVRSRPQISFLPLAEDKCQIKALHQPSLEKTRPKNMATNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MG75</accession>
    <name>A0A9P6MG75_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">GTPase of the mitochondrial inner membrane that associates with the large ribosomal subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">MTG2</name>
        <name evidence="7" type="ORF">BGZ80_006930</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003460">
        <property type="protein sequence ID" value="KAF9997774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MG75"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01898">
        <property type="entry name" value="Obg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.210.12">
        <property type="entry name" value="GTP1/OBG domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01454">
        <property type="entry name" value="GTPase_Obg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014100">
        <property type="entry name" value="GTP-bd_Obg/CgtA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006169">
        <property type="entry name" value="GTP1_OBG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036726">
        <property type="entry name" value="GTP1_OBG_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045086">
        <property type="entry name" value="OBG_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11702">
        <property type="entry name" value="DEVELOPMENTALLY REGULATED GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11702:SF31">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOME-ASSOCIATED GTPASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01018">
        <property type="entry name" value="GTP1_OBG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002401">
        <property type="entry name" value="GTP_bd_Obg/CgtA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82051">
        <property type="entry name" value="Obg GTP-binding protein N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51883">
        <property type="entry name" value="OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Obg" evidence="6">
        <location>
            <begin position="2"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="OBG-type G" evidence="5">
        <location>
            <begin position="240"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="345"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="480"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="345"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="365"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="480"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="513"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAF9997774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="524" mass="58354" checksum="D445EEEDF22EDAEB" modified="2023-09-13" version="1" fragment="single">GRNFVDFCRIKVSGGQGGDGCVSFHREKLVAFGQPNGGNGGRGGNVIFETSTNETSLQHIPHTAAAPRGVHGKGSLMHGHAGKDLVIKIPMGTIIREVPSPEKEKDPEDEELLFQKSLELGEIEAKDREMSKRWVLYPRLANSLTTLPEGKVDYFEEAQAWVAEEDRIIEARRAAMSKKPLLLDVNEFTEDGTTFLVARGGGGGYGNPHFLTTQNRSPKYATRGREGQTRWLTLELKTIADAGLVGLPNAGKSTFLQAVSNAHPAIAPYPFTTLNPYIGTVDYADSYQVKVADIPGLIRGAHRNIGLGHSFLRHVERSKVLVYVIDIAAEFGVKRKIKGVDDWSSEEKYEEPLKNEQKDDETSPPKIQQQSQQDSEIVDEAYSQPFEDWKTLLDELEAYQPGLTRRPSMIIANKADVTEVAPKNLQLFQKLVHEEWSKRRVASESGPADNEIKIVPVSAKYKKNIVKVTSILREIVEEEKAKESAAIKRKEQREQQEEEEALAFKATRRNILSHSSSNSDKSEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MH81</accession>
    <name>A0A9P6MH81_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_006256</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003080">
        <property type="protein sequence ID" value="KAG0001013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MH81"/>
    <dbReference type="OrthoDB" id="2440352at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040428397" evidence="3">
        <location>
            <begin position="24"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="21"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="125"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="35"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0001013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="158" mass="17814" checksum="5B2F71DB27136B31" modified="2023-09-13" version="1">MATTGSSSAITALLAATVGRSTASTNSPVCLNASRQERTTKDNKGKRVEDDRRAGQLLLETLKSSTTRIHDDTDADVTGNTDLTDSDISSVSTARTPLRKKRWHPNALREQYSSAMGQELFELQRQHLELLQKDWEEQKEQVKIQQEMELERLREQAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MHE7</accession>
    <name>A0A9P6MHE7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_006372</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003142">
        <property type="protein sequence ID" value="KAG0000408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MHE7"/>
    <dbReference type="OrthoDB" id="10561366at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0000408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="108" mass="12367" checksum="17A27A40ECCB6555" modified="2023-09-13" version="1" fragment="single">MNPHNLHRDDPRLRIIEELEAPIRAFNELALNHKDRYITEITQETIIHCTRILQVIPAHIMLALNGAGIKDESMVVNSLFHSARNPRLDPSRNVPPAAEDEFMRINGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MHL4</accession>
    <name>A0A9P6MHL4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">SCF ubiquitin ligase complex subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">GRR1_2</name>
        <name evidence="4" type="ORF">BGZ80_006179</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003036">
        <property type="protein sequence ID" value="KAG0001456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MHL4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050648">
        <property type="entry name" value="F-box_LRR-repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057207">
        <property type="entry name" value="FBXL15_LRR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13382">
        <property type="entry name" value="MITOCHONDRIAL ATP SYNTHASE COUPLING FACTOR B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25372">
        <property type="entry name" value="DUF7885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="F-box/LRR-repeat protein 15-like leucin rich repeat" evidence="3">
        <location>
            <begin position="113"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="474"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0001456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="505" mass="55841" checksum="4B19BDA4AD971B93" modified="2023-09-13" version="1" fragment="single">MSLDRSKTLFPYPNYVRRLNFSFLAPELTDDILVRFDSCKRLERLLLPGSNKVTEDGLKRILTVGRGLYTLDMSEIPAVTDSVLEYVANHCPKLHTLYLTGCSTITDGSVVKLAANCPGLKRIKLGQCSLLTDRSILALTKNCPHLMEIDVTNCNLMTNTAIQSVFKTLPQVRDINMTLFANLTDQAFSFIPIGPPASSNIRFDQLRVLNLTSCVLITDETLARIIPAASRLRNLTLTKCDRITDAIFAMAQLPKLRRIGLVKCANITDHGIYAMLVSQIVPQTLERVHLSYCVHLSDTAVAALVSQCSKLTHLSVTGVPAFMSHRYQKFCRTPPSEFTAHQREVFCVFSGKGVRELRQYMQEHPTVPSSTLSSIQRSYRIMGSTVASMVAGGQHSSAILAHLGFTLRETENHIQNLAAHNAAAVATTSDVATAAGTENDGEPTAILYAPSADNSEDLPNIEALSTSVADPSIQQRQENEALELEQQMEEMDQEFDYAEMMMEQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MI89</accession>
    <name>A0A9P6MI89_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_006115</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003004">
        <property type="protein sequence ID" value="KAG0001803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MI89"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0001803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="67" mass="7446" checksum="0AF4855657669380" modified="2023-09-13" version="1" fragment="single">MSDAVVVPAGTFKFSHPAYYQGVRDGFLCNVWLTSIRRFFVGAQIPADKQTLHAVIFLVGAAALWWC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MIA3</accession>
    <name>A0A9P6MIA3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptidase M20 dimerisation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_006006</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002965">
        <property type="protein sequence ID" value="KAG0002233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MIA3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016805">
        <property type="term" value="F:dipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071713">
        <property type="term" value="F:para-aminobenzoyl-glutamate hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046657">
        <property type="term" value="P:folic acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052030">
        <property type="entry name" value="Peptidase_M20/M20A_hydrolases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30575">
        <property type="entry name" value="PEPTIDASE M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30575:SF3">
        <property type="entry name" value="PEPTIDASE M20 DIMERISATION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="Bacterial exopeptidase dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0002233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="202" mass="21920" checksum="B45FBB60CEAA3894" modified="2023-09-13" version="1">MTYNAIGLLRQQTLPSNRIHSVVTNGGQAANIIPELASMTTMYRANKNEDLVKLHDQILEIVESSAAATGCTVKVEKAMEYLPLNTNPTLADRYGSYMTSFGVHYQPREVDEVTPAGSTDMGNVTFALPGIHPVFNIASLDGVREPGLSTHSLLFAERAGTELAHKSVIRAAKGLSLTGLDVLLDADFTKAAREDFERSKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MJ77</accession>
    <name>A0A9P6MJ77_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005589</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002750">
        <property type="protein sequence ID" value="KAG0004632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MJ77"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0004632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="225" mass="25967" checksum="1A594F99B9DC99BD" modified="2023-09-13" version="1" fragment="single">HYFESHIRGPVIPPLRRSNIAITPVPTNDDPETLTNKDHGSRPFTESTGSSCITSTRGDKHSGSDLNGNDDEDNSGACGHDDRCEGIEEGYDYKYDGTKEYVEEELSETEDELRDAVDYIRREISNRAERSAYYSSTDDTDDINPSYWDCPEDIVKPLLKQEDYKRMRSLFMARNSILRTYGLSDDEYSDLTCGHESRHSEESLWLDDDQVTKRIELWKQERCQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MJW1</accession>
    <name>A0A9P6MJW1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Sacsin/Nov domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005444</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002687">
        <property type="protein sequence ID" value="KAG0005414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MJW1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030544">
        <property type="term" value="F:Hsp70 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058210">
        <property type="entry name" value="SACS/Nov_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052972">
        <property type="entry name" value="Sacsin_chaperone_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15600">
        <property type="entry name" value="SACSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15600:SF42">
        <property type="entry name" value="SACSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25794">
        <property type="entry name" value="SACS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sacsin/Nov" evidence="1">
        <location>
            <begin position="14"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="718"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF25794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0005414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="718" mass="81727" checksum="D749DA61C4E976B5" modified="2023-09-13" version="1" fragment="single">MTIHLSGFKSHGIREPLTNRIAGILDEYPDGTQIARELLQNSDDARSTVQWYLLDHHSYIDNANGDSDLRLFHEDLKEYMGPALLAGSDSLFEERDFKSMKNLAASEKRNDETKIGQMGIGFNSIYHMTDCPSFISGDQLMVIEPHERIFNGVRSEFMEGAVRGSFAEGNQGLNIFPDQLKAFSILEDIDFSRVYPGTIFRFPLRTANQAETSKLSKNAYPAEKVLEMLLKLKNEALKAMLFLKHIEKIAIYERKSLEEGPKKIFEIEIVNAKDVRKERQELLTKLRGHVYPESTASRDIILEYSVRPIFKLTQDDGTSTVEHWHISTIVGNVLASRGYMEEETEGNLDAHKLIPWVGIAAPSEPGVMIASSGLFCFLPISIQLPFPVHINGHFAVKQSRREIWTNQDNDFAKHASAYIKSVWNVHLFHTHVPLVYAKFLADLGLARGANYDLWPTSCGLGIGLDAIWKDLLTNLVHVICRDNLKVFFCKSDDDEDHHLADYKSLWIADRDIDSYPLLAETLQRLTNVAVGLPDAVIRTIPNVIGSLGLESRILTPALVRKLLRKHKSQWSSTASPEARVEMLKYSIEDDDIKDLEGLPLLPLASGLWVEFSISQARARYLVKQEIFTVLSHSNRGLVDIEFDKPVVRRFYTNQAFHVFWSEVDDSVISARIKDTYDRNFYNGSSKTKSYIPQPVDGFPTNKWIHDFWIMVRLRPDQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MKD6</accession>
    <name>A0A9P6MKD6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Carrier domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_005566</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the NRP synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002740">
        <property type="protein sequence ID" value="KAG0004747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MKD6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043041">
        <property type="term" value="P:amino acid activation for nonribosomal peptide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17643">
        <property type="entry name" value="A_NRPS_Cytc1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19544">
        <property type="entry name" value="E-C_NRPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.30:FF:000010">
        <property type="entry name" value="Enterobactin synthetase component F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12780:FF:000012">
        <property type="entry name" value="Non-ribosomal peptide synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.980:FF:000001">
        <property type="entry name" value="Non-ribosomal peptide synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.38.10:FF:000001">
        <property type="entry name" value="Non-ribosomal peptide synthetase PvdI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1200.10:FF:000005">
        <property type="entry name" value="Nonribosomal peptide synthetase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.980">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.38.10">
        <property type="entry name" value="Luciferase, Domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF1">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="614"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0004747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1242" mass="137903" checksum="4DF53FD6826B1043" modified="2023-09-13" version="1" fragment="single">PAKSSQNPNSPHLEILDMERSNYPIAMNVGDSGLDFRLSCQAVHPIDASKICGYMQQSLQSLVDALDDAPNKKVRDLEVMPIVEREMLLQSWNTTESYPSDQSIHKTFEDQVKQSPDATAIVCEGQQMSYRELNARANSLAHRLIDLGVKPDSLVAICVDRSLAMIIGLLAILKAGGAYVPLDPMFASGRLQDILTDAAPSILLADESGISALGNSISKSIVVIDPNESFETSIVDPQVSGLTSHHLAYVIYTSGSTGKPKGVMVEHAQVTRLFDSTAAWYKFSETDIWIMTHTFSFDVSVWEIWGALRHGSKLVIPSYRTTQSPDDLYRMICDHGVTVLNMTPSAFRPLIRSQAQLDLQDKLRYVILAGEALEPAILHLWYSTRSSDYTQIINMYGTTETTVHATFRIMRPEDHKLAISPIGVRIPDLTFYVLDDRGNPVPLGAIGELCIGGAGVTRGYLNKPDLTSERFPLDPFNKTEGTRMYKTGDLVRYLPDGNLIYLGRNDYQVKIRGYRVELGETEACLLEHPAVREAVVLELDEGSNKRLVAYVVVDPVERLAHTLWTHVSAKLPEYMIPAAFVRMDVFPLTTNGKLDRRALPEPSSDAFASQGYEAPQGEIEKTLAAIWSDVLKVDQIGRHDNFFMLGGHSLLAVQMIERLHRVELNLSIRDLFETPTLSALSQSLNKHHIDAMAPTNRITPDVTVITPDLLPLIDLSQDDINTIVKQVDRGVANIQDIYALSPLQDGILFHHIIATKGDPYLLTNCLVIDNRDILDRFIETIQKVVDRHDILRTAIIWEHLSSPAQVVIRQATLTVTEMVLDLANGPASKQLLELFNPREYRIELSQAPLTRFAVAQDIDGRWVVVQMMHHIIGDHSTMKQMMIEIQAFLEGQDEVLPSPQPFRNLIAQARSGPSVEDHKKFFSEMLVDIDTPALPYGVSDVHSNGIDITESNCMLPQILSSRLRGHAKRMGVSLASLCHLAWAQVISRTSGQERVVFGTVLFGRMQSGSGSDTAMGLFINTLPFRIDLDDGGVQDRVLQTHGNLARLLDHEHASLALAQRCSSIPAGAPLFSAMLNYRHNNTPSSENQSLSGIKILEGIERTNYPFVMSIDDGGDTLGLNAQVIQPFDPSRICGYMQQSLQSLADALDYSPEMPVQNLETLTPDEQELLLHTWNTSGMPHPDHLCIHQYFESQVTQSPDAIAVVFEDQQMSYDELNAHANTLAHHLISLGVKPDTLVAICVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MLR2</accession>
    <name>A0A9P6MLR2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">FAD/NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_004889</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NADH dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002447">
        <property type="protein sequence ID" value="KAG0007255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MLR2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003954">
        <property type="term" value="F:NADH dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045024">
        <property type="entry name" value="NDH-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054585">
        <property type="entry name" value="NDH2-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706">
        <property type="entry name" value="NADH DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706:SF13">
        <property type="entry name" value="NADH DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22366">
        <property type="entry name" value="NDH2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="6">
        <location>
            <begin position="1"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="External alternative NADH-ubiquinone oxidoreductase-like C-terminal" evidence="7">
        <location>
            <begin position="371"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF22366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0007255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="454" mass="51122" checksum="5D5B506ABD427ACC" modified="2023-09-13" version="1">MILGSGWGGFKLLKDMDKNAYQIVAVSPRNHFLFTPLLASTSVGTLEFRCITEPVRGYTRDVEYHQAWCDSVDLENHKIDCTTNLSKVPATHISDPAGRSLSLESSNKFRLDYDHLIIAVGSYSNTFNIPGVKEHAFFLKEVADARKIRTRVLECFERAEMSRSDEEKNGLLHFAVVGGGPTGVEFSAELHDFIREDCSRLFPGLMNHVTLAVYDVAPTILANFDKSLADYCMTKFKRSGIDVRTGTVVEKVEDGMLVLKGGKQIPFGCLVWSTGLTENPMTASLEGKVMKSKSKRILTDSYLRVLDPEGKVIPNVYALGDCATIQDHELPQTAQVANQQAIWLRKALNKLAKQPEKSLTDVTGPFSFKNLGSMAYIGNWEAVVDMTKINDKAKESGRFAWVFWRSSYLTMSVSMRNKMLIPMYWLATWVFGRDVVSFQEYDRRKRLMNTERDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MM51</accession>
    <name>A0A9P6MM51_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mnd1 HTH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_004390</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MND1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002240">
        <property type="protein sequence ID" value="KAG0007663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MM51"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005647">
        <property type="entry name" value="Mnd1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040453">
        <property type="entry name" value="Mnd1_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03962">
        <property type="entry name" value="Mnd1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF026991">
        <property type="entry name" value="Mnd1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mnd1 HTH" evidence="6">
        <location>
            <begin position="24"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="87"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0007663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="161" mass="18373" checksum="B4E3E9C35A3C1A9D" modified="2023-09-13" version="1" fragment="single">MASRMHTSWTSRKGLSAADKRTKLLELFHESGTFHKLQELEKSAPKLKGIVQQSVKDVLQSLVDDGLVTVEKIGTSNYYWSFPSAVQQSKKGKLQALRDEYQRLEKANAELEASIKKASSGREDSEQRQELMAKLLEAEAEDRRLQQEIKRLPKMQRIDGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MN62</accession>
    <name>A0A9P6MN62_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">JmjC domain-containing protein 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">JMJD7</name>
        <name evidence="2" type="ORF">BGZ80_004155</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002149">
        <property type="protein sequence ID" value="KAG0007850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MN62"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041667">
        <property type="entry name" value="Cupin_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461:SF99">
        <property type="entry name" value="BIFUNCTIONAL PEPTIDASE AND (3S)-LYSYL HYDROXYLASE JMJD7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461">
        <property type="entry name" value="HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13621">
        <property type="entry name" value="Cupin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="1">
        <location>
            <begin position="180"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0007850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="270" mass="30819" checksum="1924756FE9913EA1" modified="2023-09-13" version="1">MAATEPRSRISNVSALKMRLEEEISTLISEAQGRGLVTCHYHLPIDCNHDSRALRASSTAEEKQWAWPAFTKWTNEYLSKTLGEKEITVACTPNGWADAVVDDKYFAMPCEKKMTFEQFLDGMPIRTQKNKTISDDYVEPGGQDCYGVENRFKDLGLKDGEQEMDPYQEVRYIQLQNGNLMTEYEELLGDVPSDISFASEALAKQPDAVNFWYGDERSTTSLHKDHYENIYGVIAGRKIFTLIPPTEQYCLHGKEIRPPRILNVCEHYSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MND5</accession>
    <name>A0A9P6MND5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Guanine deaminase</fullName>
            <shortName evidence="8">Guanase</shortName>
            <ecNumber evidence="8">3.5.4.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Guanine aminohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_003647</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 8">
            <text>guanine + H2O + H(+) = xanthine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:14665"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16235"/>
            <dbReference type="ChEBI" id="CHEBI:17712"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Purine metabolism; guanine degradation; xanthine from guanine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.3" evidence="8"/>
    <dbReference type="EMBL" id="JAAAID010001981">
        <property type="protein sequence ID" value="KAG0008257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MND5"/>
    <dbReference type="OrthoDB" id="194468at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008892">
        <property type="term" value="F:guanine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006147">
        <property type="term" value="P:guanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.140:FF:000022">
        <property type="entry name" value="Guanine deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="entry name" value="Urease, subunit C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014311">
        <property type="entry name" value="Guanine_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051607">
        <property type="entry name" value="Metallo-dep_hydrolases"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02967">
        <property type="entry name" value="guan_deamin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11271">
        <property type="entry name" value="GUANINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11271:SF6">
        <property type="entry name" value="GUANINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="9">
        <location>
            <begin position="73"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00051148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00056079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0008257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="454" mass="50700" checksum="95B2E88DF42C5862" modified="2023-09-13" version="1">MKTFASSITKVFYGTLIHSVSLKQIEYIKQGLLFIDNQGKIARLVKNVAQDKVESTLEGVESDKVIRLNEDQFVIPGFIDTHIHAPQYTFCGNGHDLPLLEWLDTYTFPRESKFADRDYARKLYTKSVARSLRNGTTSACWFATIHLDACKELVDIIQEQGQRAYVGKVNMNQNSPDFLVETTESSVKDTRAFIEYVKGVNSKLNHNPLITPIITPRFAISCTSELLAELGKLAQEYDLPIQSHLCENLNEIGFTMSLFPDSANYTSVYADHGLLNDRTIMAHCVHMKEEELDLMKQKNAGISHCANSNFNLKSGMADVRKMLSKDIKVGLGTDVAGGYSPSILEALRASRSCSVARNVDTTLLVAELFYLATVGGARVMELDDIIGNFEVGKEFDAILVNTAVDNSPVDVFDHDTIETKFEKYLFVGDDRNNEKIFVQGKEVRLPGSNVVSHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNP3</accession>
    <name>A0A9P6MNP3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003231</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001846">
        <property type="protein sequence ID" value="KAG0008627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNP3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0008627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="261" mass="30318" checksum="D3818B8B26844A04" modified="2023-09-13" version="1" fragment="single">MSPTSLSQMTSEFLRSYHGYRGSQWKLSSGTIVDETFCQYIMTMKHESPLHSFIILGEPDLEPFSEDDRLLIKDFLRQSDLDHIKFSLIEWKKMELLQYQLSRHDIITLLNNGLSNLPRLQDTQDRSIDRDEFDAFRACAYFSLYDIYQVYQSKNFKIPQEKNESWYRNILWGFLWKLFGFDQKLTFQPGEKSSNASSHQRNKDRSDPKVTLTQGSKVDGIISCDTTHCELCIIEAGAVDVCPNGTKTLTDRIKLAKTLKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MP01</accession>
    <name>A0A9P6MP01_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Target of EGR1, member 1 (Nuclear)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">TOE1</name>
        <name evidence="8" type="ORF">BGZ80_003461</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CAF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001918">
        <property type="protein sequence ID" value="KAG0008421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MP01"/>
    <dbReference type="OrthoDB" id="414075at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015030">
        <property type="term" value="C:Cajal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017069">
        <property type="term" value="F:snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034472">
        <property type="term" value="P:snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051181">
        <property type="entry name" value="CAF1_poly(A)_ribonucleases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006941">
        <property type="entry name" value="RNase_CAF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15092">
        <property type="entry name" value="POLY A -SPECIFIC RIBONUCLEASE/TARGET OF EGR1, MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15092:SF37">
        <property type="entry name" value="TARGET OF EGR1 PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04857">
        <property type="entry name" value="CAF1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="298"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="298"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="334"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0008421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="467" mass="51893" checksum="0D1B21CC71FAC46A" modified="2023-09-13" version="1">MPPVPLPLPTYNQVTKHNLAQLQPMIVLLLKQAAFIALDAEFTGLGPKGVTTRASDIQERYQHLCDLARSHALVAFGLSIFIRAESSGESPEGAAPASSKTGSGTGARSDLEQSYQVHNFNFSMLSEADYTVSPKSMLFLAENGLDLNQWILEGIPYTGGDRLTNEGGRGNPNGIMRSIFKRIMTRRIPVVIHNGFLDLIFLYYSFYANLPPKLETFVADLSDMFPGGLFDTKYISDYITRERSSFLAYLFRKYERHNSRAKDEADPSARGIYSTFGVQPRLALPPIQETKPETKPSASGVAYCEDYAFHGVCKKNMKCGKSHDLDLILDAEEEQRDSKKRKRQKQSHDAAKIQQAVSVNGTSDTSPTGVAAEAPNMLKAPESKTVAVMTTAKTIENSVLPGEKFHSAYFDAFMTGTIFSHQVNQHQAEEVDAKARNKIYLIGKSFPLKIEKSAFAKYSPEHERQRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MP17</accession>
    <name>A0A9P6MP17_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Chaperone ATPase hsp78</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">HSP78</name>
        <name evidence="10" type="ORF">BGZ80_003048</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the ClpA/ClpB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001786">
        <property type="protein sequence ID" value="KAG0008792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MP17"/>
    <dbReference type="OrthoDB" id="47330at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034605">
        <property type="term" value="P:cellular response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043335">
        <property type="term" value="P:protein unfolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19499">
        <property type="entry name" value="RecA-like_ClpB_Hsp104-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000017">
        <property type="entry name" value="ATP-dependent chaperone ClpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000120">
        <property type="entry name" value="ATP-dependent chaperone ClpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000025">
        <property type="entry name" value="ATP-dependent Clp protease subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000010">
        <property type="entry name" value="Chaperone clpB 1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018368">
        <property type="entry name" value="ClpA/B_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028299">
        <property type="entry name" value="ClpA/B_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041546">
        <property type="entry name" value="ClpA/ClpB_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050130">
        <property type="entry name" value="ClpA_ClpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11638">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11638:SF176">
        <property type="entry name" value="HEAT SHOCK PROTEIN 78, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17871">
        <property type="entry name" value="AAA_lid_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00870">
        <property type="entry name" value="CLPAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00871">
        <property type="entry name" value="CLPAB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="8">
        <location>
            <begin position="156"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="8">
        <location>
            <begin position="581"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="domain" description="Clp ATPase C-terminal" evidence="9">
        <location>
            <begin position="775"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="370"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0008792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="871" mass="96312" checksum="6BD88CA0C6F8344F" modified="2023-09-13" version="1">MFTARNSILSTARTTGTRVNGSYLSATRRKLSSVAQISLGSTNRSLRTSVASHSLDTTTVLPKTARHGLLATVALYGTKSGHIAVPWLGAVRLYQTGRGGPQGFRIQPSQEQNEKGKALEQYGNDLTKLASEGKLDPVIGREEEIRRTIQVLSRRTKNNPVLIGEAGVGKTSIAEGLAQRIINGEVPESIKDKRVISLDLGALVAGAKYRGEFEERLKAVLADVTAEEGKIILFIDELHTLLGLGKSEGAMDAGNMLKPALARGSLHCCGATTIDEYRKYIEKDPALARRFQSVMVNEPSVEDTISILRGLKERYEVHHGVRIADSALVAAAVQSHRYITDRFLPDKAIDLVDEACSKLRLQQESKPDVIESLDRGIVTMEIELESLKKETDPLSVSRREKLEDDLAKKKEESQRLTQIWKQEREKLDTIKDLKAQLEQARIDLEAAQRKGDFTRASELRYGVIPGLEGKLPKEEKVPTELIEGSIAGMGAEDTEKPMGPLGTQEEVESLIHERVTADDISRVVARMTGIPVQNLLKGEKERLLGMENALARRVVGQDEAISAVAEAVRLSRAGLSNPSRPIASFLFLGPTGVGKTELCKAIANFLFDTENAIVRIDMSEYMEKFSTSRLIGAPPGYVGHEEGGELTEAIRRKPYSVILFDEMEKANKDVFNLMLQVLDDGRLTDSQGRTVDFRNTIIIMTSNLGADMLALADDDTSTTSSSILSKLTKKGETVDNDKESKVTDEEKEAVMQVVRRHFAPEFINRIDDMVVFNRLSHKAIRDIVDVRLQDVQKRLEDRRITIDADSSAKEWLANRGYSSAYGARPLNRVIQKQLLQPLAKRIIEGKIKVGEKVNVTVENDQLKVVPPAELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MP75</accession>
    <name>A0A9P6MP75_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_002605</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001649">
        <property type="protein sequence ID" value="KAG0009228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MP75"/>
    <dbReference type="OrthoDB" id="1738954at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14096">
        <property type="entry name" value="STKc_RCK1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000042">
        <property type="entry name" value="Aurora kinase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000313">
        <property type="entry name" value="Serine/threonine-protein kinase srk1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030616">
        <property type="entry name" value="Aur-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24350">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE IAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="187"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="558"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="10"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="22"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="38"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="77"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="111"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="310"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="216"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="264"/>
            <end position="266"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="314"/>
            <end position="315"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="359"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="cross-link" description="Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)" evidence="8">
        <location>
            <position position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0009228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="748" mass="82878" checksum="84E45FC6C63B6433" modified="2023-09-13" version="1">MAPIIASLKKLIRRGKKKQKNSTSSSSVAVSASTMSTRDSGTSLTSAANSLPPSNHSKDRSSASQPHPHPHPRSRSTSKISKTFISKPASRTPSPDRTASAGLNILPCNSEMPNSEMPNSEMPTNQSDAVTSATPSVQQFIASPVVNTASSNVVNSSTKHNEAVSRMIAEANQQKNTLPTYPGLEQFVLIEKMGDGAFSSVYKAHDTKANRTVAIKVVRKYDMSAHQRANILKEVQIMRQLKHRGVVELYDFSESDEHYFLVLELATGGELFHRIVKLTYFSEDLARHVIVQVAEAIRYLHEERGVVHRDIKPENILFEPIPIIPSPPGYKPDEEDKEDEGIFQPGIGGGGIGRVKIADFGLSKIVWDEQTMTPCGTVGYTAPEIVKDERYSKSVDMWALGCVLYTLLVGFPPFYDESIQALTEKVARGQFTFLSPWWDEISFEVKDLISHLLCVDPNERYTIDQFLAHPWIRAGEQDIQSTVQEALGSPAFETYAAAPTPFMVENKILAGVAAMTPDYGGPRTPKTPYKRRAENPLSPGIGLKEVFDVSNAVHRMGEESRRRHVVQPAVHQGHQDIDGIQRQAFMTQLNEEDEDEELSDDSGSTSAINEDESIVMGINDVQINENGDGRDIDTLHRQQKEYQKAQEQIAAEKRSQYLKKQQKAGQTIPSHHISSAFNHQNHAYNVSNAASTSVSNTSSSASRRRRAGFELNMDHATLLKRRAKQQDTHPPNAAYQNLMTQQTPVVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPF2</accession>
    <name>A0A9P6MPF2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Dual specificity protein kinase kns1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">KNS1_1</name>
        <name evidence="9" type="ORF">BGZ80_003491</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001926">
        <property type="protein sequence ID" value="KAG0008401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPF2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043484">
        <property type="term" value="P:regulation of RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14134">
        <property type="entry name" value="PKc_CLK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051175">
        <property type="entry name" value="CLK_kinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45646">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE DOA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45646:SF11">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE DOA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="345"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="63"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="115"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="175"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="204"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="374"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0008401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="677" mass="77470" checksum="D8D7EF2C996C3834" modified="2023-09-13" version="1" fragment="single">MTTLRTRTGKRPTDWAEFYKNGPPQEVIVIDDDTPPPSSSSSTSSHHQVPGSNGRHYHHRSSNVDSVQPGSSPRSHVMPPPNPSYHSSHADYPHSHAGAHGFSTNGHSNHDSHYRFSNASRPVAQQTVSEQTDLMTRRSNKRLPSMELIPVGSNGSYSRPASPSSQHRRRHNHHYQYPPQHQYHSQSGGHDSHRYDYPDPPYSPVYDHYQHHQQYSPQSHQHQNHHYQQQQHHYRQDQHQYQPPPTSPAYSNDFGPPSETIILDPIPRARKRRKSNPDVKYIAPPPLPPISQNSHAYSGYYQPHGPSTTNIPPPSSRDAPPIMPLWDDKEGHYVVVPNEDLTSRYKIIRLLGQGTFGKVVECYDRDTGKHCAIKIIRAVQKYRDASKIEARVLNTLKRNDPGNAFKCLHLNDCFDYRNHVCMVFELLGQSIYDWLKDNSFCPFPPNQIQQFARQLFSSVSFLHSLRLIHTDLKPENILLANGSYRQMPYKSKTRRVLLDPEIRLIDFGSATFQDEHHSTVVSTRHYRAPEIILVEFLTGEALFQTHDNLEHLAMMQAVLGPIPEKLIRASHKSSQKYFVHGRLDYPNEETKNNSRKYVKALRPLREYVIPPESNASHISNSFALDFLDLLTRLLAYDPAERITASQALKHPYFDYIVDESGRVHGLKTSPPAKSSSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQB0</accession>
    <name>A0A9P6MQB0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_002557</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001635">
        <property type="protein sequence ID" value="KAG0009276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQB0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="236"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="311"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="311"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="371"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="396"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="407"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0009276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="439" mass="49526" checksum="50A56AEDD9063493" modified="2023-09-13" version="1">MENGQGLDQRRQVYISGFQNTAESLHALDTPQRRMTQSPNLEGAADTSAQLARRQASVRNIMARYYQGGPRSPTFGHSSQNIGSDMVQSQYDGGPDSQLLYEERFQASGQHPVSDRLYHPSQQARDNSMSASVEFSSSGHARSSRRPLSQQDHHSYSGSIIPAAPPVRQGSVIHRSGRYANDRVFSDDESMHGWGTASLDQLPQRSKTGSYSVRLQHLRGRLDQMQPLHQQLEEFERQEQYADQQQQQQQQGEFSDGADSNMFTEGRTPSFAQRRQPLPKQWQQQHSQQYQDIIEHQKHMQRQPFQHHQDMMMTTPSMPSPNSSPSSSSRLDAPSLASSNSHQGGLAGLDARYHLSPRGTADSSTFPRQMSIGSISGFSDDGQYMHHQQQQQQQQPKRISQASHRSQFQPQQRQQQQLSHLDGLSPQAQARLQQVLAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQE2</accession>
    <name>A0A9P6MQE2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_002490</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001617">
        <property type="protein sequence ID" value="KAG0009337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQE2"/>
    <dbReference type="OrthoDB" id="2443140at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030427">
        <property type="term" value="C:site of polarized growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005034">
        <property type="term" value="F:osmosensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030010">
        <property type="term" value="P:establishment of cell polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006972">
        <property type="term" value="P:hyperosmotic response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007232">
        <property type="term" value="P:osmosensory signaling pathway via Sho1 osmosensor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001402">
        <property type="term" value="P:signal transduction involved in filamentous growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039295">
        <property type="entry name" value="MSB2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35778">
        <property type="entry name" value="SIGNALING MUCIN HKR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35778:SF1">
        <property type="entry name" value="SIGNALING MUCIN HKR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="500"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="268"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="459"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="268"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="459"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="482"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0009337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="557" mass="57669" checksum="B30B286062E47B6D" modified="2023-09-13" version="1" fragment="single">ANGDTIFPVSLDLGLPDPTPAVTASTKVSSSVVAASTIGAAPVSAPTTKSKSKPKTKTETKTKAKTKTKTTSKAKTTSKSHKSSSSTRRPKKTRTSTSSTPTTISPAVDPEPTVTTQPSVTNTYEPTTPDISITIGPIAPTTVPDTSIPTTAEATPSVSVTSELPGATSTSSEVPGATDTPSMSTPLVTVSQPLPTTPSSNSTSIPIDPTPTVSISPQVNVTIPVTINSTATINSPTVGAPVTTTITNTTTTITTANATITTTTTTTTTTRAATTKPTTVKTSTTSHHTRHTKTTTTKAWLPSSIVPILTAPQTTTTPSPGTSLPAVVIPNLNPKIPHNSFNVRLRFERVSYYQVINNGILAAQLVSFVPEQLAKALKVKSSSILVLAIRDGASTTSSSNKKRELVTTDSVTDAILATVAIPKSKYWALNSLVKNPNSTLYATEANSFGQFLDSTYPLSTSPPATTSGSSDGNASADPLTDSGTIPTPGSSSSSSTNAPLIGSIVALATIAYVGIAMVVVRRYRNKKLKEQERENLTRSISAPYNIQGGSQGWGWSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQJ7</accession>
    <name>A0A9P6MQJ7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001911</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001453">
        <property type="protein sequence ID" value="KAG0009946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQJ7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="338"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="521"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="351"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="522"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="538"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0009946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="596" mass="66146" checksum="46DCEAE853233FE7" modified="2023-09-13" version="1">MTANSSSATEQNGSPSDTDFLTTWKQNLLMSDVARFKLPSSFTKSSKPRRVALSTLPSSSIVVYPDHILKQLRVPHWDHCREYVNHLLPLADAIQYSNSAVAFPLSSLKFLDEVYSIRIEHQQQFKEFLGWVPTTLSKHHPALATQILDELNNTRACLTAILPSTQMSIPATSCFANERWLDIDCLQACLDALNRMYNTSGNIFILPIDLTIYVTSNDDHSDYHYKRTFDVKSLTDILGIFPVKVEDCKDGEGCCCDDDDGCKDGCNCDDHCACNGPGHCDHAHPCVCEPDHWAFFWLNLQRSEFLFGDSLGNDQPAARIIRLKNFIAKALHTFDQNESGKDEQWPTLRLSPPSAAAESSPSLPADPAPFTSSFTLEATTNSSSTADTTSLSSLSLTHNQDSTSNTLYDNAANASLKEPIIPTFSIDPATLPIDYNFAESVFETPDHALQTIYAFANAHQFPIVRQKTHLDPKKYKHPSAPKWKVSLYGKDGAGFGHNHALGPSIMRGRKNVCPELNTLFASRDDTTDEPSSKKPCLESSSKDSQPLTKDPETTLSGLFNFIRTGCNHNLSDKPCIIQSIYEHARDLFQNIPGSNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQN1</accession>
    <name>A0A9P6MQN1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Ubiquitin thioesterase OTU</fullName>
            <ecNumber evidence="11">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">OTU1</name>
        <name evidence="14" type="ORF">BGZ80_001847</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degradation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="11"/>
    <dbReference type="EMBL" id="JAAAID010001432">
        <property type="protein sequence ID" value="KAG0010031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQN1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030968">
        <property type="term" value="P:endoplasmic reticulum unfolded protein response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22745">
        <property type="entry name" value="OTU_OTU1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.70.80:FF:000016">
        <property type="entry name" value="Putative ubiquitin thioesterase otu1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003323">
        <property type="entry name" value="OTU_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057766">
        <property type="entry name" value="Znf-C2H2_OTU1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13312">
        <property type="entry name" value="HIV-INDUCED PROTEIN-7-LIKE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13312:SF0">
        <property type="entry name" value="UBIQUITIN THIOESTERASE OTU1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02338">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24560">
        <property type="entry name" value="zf-C2H2_OTU1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50802">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 14" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 11" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="7 11" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="OTU" evidence="13">
        <location>
            <begin position="82"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="48"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU367104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0010031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="277" mass="29947" checksum="63A60CDA06AB4E62" modified="2023-09-13" version="1">MFTAQPTSTSGGFGSRPVVQPSGALSAFQARATSGNVFGGLSTVNSAYKSNPPSATQPPKIQPPTMPSSSIDAIRVRDLGLLVVREVEDDNSCLFNAIAYTLDPTMKNNVQGLRQIVAQAIEASPEAYSDVVLGRPRNEYCDWIKRENSWGGAIELAIFSEHYNIEIDSIDVSTGRVDRFGEGQYNQRALVMYSGIHYDALAITPGLDIPGECDQTQFDVSSEDIVNAGVQLAAKLKKAHKYTDLATFTLRCSICQAGLQGEKDAQQHAQQTSHTSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQW8</accession>
    <name>A0A9P6MQW8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001858</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001436">
        <property type="protein sequence ID" value="KAG0010016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQW8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="612"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0010016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="754" mass="84923" checksum="5092A3FD85EA0EB6" modified="2023-09-13" version="1">MAIKHSQPQSMGALTHFVTESDTSLLSSTHAPGVLPLHDYDYKGNFDGCEEQEQRFPCPYHESEDVELNYGDNEEDYISCDEDCEIEGEDGDVEDLPSDLRTDQQRRQPPTRANSSKVEGVVSPQCPSVFLTTEGSFSAPSYTSSSTVPFTSTSSMDILSPNQVTCQRIPSQLQDYSLAFCISNEDCSRGFIQIVRRNGAVDPSLRFKVSEDPGHDRHFRQVAGPDDFYFVIEGAQKLALGAHLVPSDLLVKVDGNSTSSSTDSQDLIYRADFRMTLPGPVQLSGWLRYEKFRAVRENRPGVWPQWTHSVLINPKTTVDLANIEFNICSNCELDSFLDQVKTYREEHFEQCDRMAPVRGSYWKEDLALRVYSKLDTINTEPGAGFFLEDKDEKLVKSLNKDDENYTRAPKLTRGWRFVPSGCTMTKTSSLPNASSQDPYIPTCDSVESPGAAMRAPLSQRSNEAIAENKYPRRRILFTGDSQVRTTYNAILSHYRPLDPVHQQFGFHDEFLPGSETLNLNHTITMKPTSASVIRRKETDTEIELIYKADQFLDFLVTSTDKELDVYDTIYLNLGQWPASGPVAGGQWATATLLERWEAVIKRLNRWKLSREEQIKTRSPRPGGAKGSPTAGTGDSSIVIWAGMNAFPMRTDPSIQVKGDWRTNARLGYWDDWIETISQEAGGWFRRMNAWQLTFPMLDQVVDRAHFQQTDAIDALKIEALYKLDLCSRMRPDTPYSSPLADTITSTTITTTTTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MR99</accession>
    <name>A0A9P6MR99_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">NodB homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_001295</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001293">
        <property type="protein sequence ID" value="KAG0010648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MR99"/>
    <dbReference type="OrthoDB" id="407355at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10951">
        <property type="entry name" value="CE4_ClCDA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471">
        <property type="entry name" value="CHITIN DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471:SF2">
        <property type="entry name" value="CHITIN DEACETYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040413949" description="NodB homology domain-containing protein" evidence="6">
        <location>
            <begin position="22"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="NodB homology" evidence="7">
        <location>
            <begin position="49"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0010648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="254" mass="27920" checksum="B668C6A8FFBEF68E" modified="2023-09-13" version="1">MAPISRLAFIAMLFSAAFVNAAPADTASSPTHELYKRGVNIITSCTVKGTVAITFDDGPYLYTSDLLDILKKKGVKVTFFMNGDNYSKITSSKYAAVVKRAYKEGHQIASHTWDHKDLTTLSKSGITKEMTKLETAFKSIIGVRPTYMRPPYGSVNSLVLSTLSKLGYKIVTWDEDTEDWKHPKNPAASYNLYKKVLTSSGVKKAGHIFLEHDVNHDTALVLAPEAIDLALKKGYKVVPVGTCLGASKSSWYTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRJ6</accession>
    <name>A0A9P6MRJ6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_000880</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001197">
        <property type="protein sequence ID" value="KAG0011166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRJ6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0011166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="305" mass="33836" checksum="F1211CC80430B159" modified="2023-09-13" version="1">MGVFKYNVGDRVSIEYFVNVLGKDGKIVCTEKLVPTKLSIAEPEEILFSQSSYIQQEGFITPMVYTTENPFNFIPWYGGLAEVTITGMGCKEYHSDEWIAKDTLKIRQAVVKVEEKGCITQPSIQDGMLTWQAVGQAGCRINFHVDSALDRTASYGALQLLLQDTFYLIIENKRIHVANNADDDEPVLDAPTTDVAHDGFELPAGNENIVRFTDSPGMTLDGIRGEQVPIGGDAVLWWGIEAQATLDNGAWTVNSAKSGVTREPEIDPKSPNFMAEYNNYAQNSSLQLANYNKDTGCYVFTKDFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MS34</accession>
    <name>A0A9P6MS34_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Steroid 5-alpha reductase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_000516</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001107">
        <property type="protein sequence ID" value="KAG0011666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MS34"/>
    <dbReference type="OrthoDB" id="201504at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010721">
        <property type="entry name" value="UstE-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32251">
        <property type="entry name" value="3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32251:SF23">
        <property type="entry name" value="3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE (DUF1295)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06966">
        <property type="entry name" value="DUF1295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50244">
        <property type="entry name" value="S5A_REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="256"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="287"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0011666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="341" mass="39213" checksum="7FB198D3C9C9215B" modified="2023-09-13" version="1">MVTLANVFSWESFGKLLLNGYNNLSLPNSDNTSLLLDLVIFHAASDPFIFAVRMSLLFAFICWFQSMATGKYSWVDKIWSIAPMIYTIHYSTRNILYWPKDEPYVHMPRVYIATLLIVVWGVRLTYNFYRKGGYGMDSEDYRWPFLGSIIPSILWLFFNIIFISLFQNLLLVALTAPVYLAWKACIVEMTPLNWVDAVATLLFIGGLTLETIADNQQWEFQESKKKAIANKENLIGDYKRGFLTQGLFKYSRHPNFLGEMIIWVSVYLFSIAAGYPTYDSSINPSIVGPAVLILLFQFSTFLTEYLSSQKYPAYKLYKKTTSRFIPLPAGTSLDELEKKSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSB2</accession>
    <name>A0A9P6MSB2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ricin B lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_000853</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001189">
        <property type="protein sequence ID" value="KAG0011197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSB2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0011197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="91" mass="10333" checksum="C59C1AB796A0A982" modified="2023-09-13" version="1">MLFPEDRPFGIRLCGSNLVIDVSGACDDIGTNIIVWHQKLGDNANQRWIYENNKLRSLKSGLILSAPQLEYYAKAEQQHDTGMKGQSYKYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSH2</accession>
    <name>A0A9P6MSH2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">rRNA methyltransferase 1, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BGZ80_000216</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001039">
        <property type="protein sequence ID" value="KAG0012075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSH2"/>
    <dbReference type="OrthoDB" id="270651at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016435">
        <property type="term" value="F:rRNA (guanine) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18105">
        <property type="entry name" value="SpoU-like_MRM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047182">
        <property type="entry name" value="MRM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047261">
        <property type="entry name" value="MRM1_MeTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013123">
        <property type="entry name" value="SpoU_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46103">
        <property type="entry name" value="RRNA METHYLTRANSFERASE 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46103:SF1">
        <property type="entry name" value="RRNA METHYLTRANSFERASE 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08032">
        <property type="entry name" value="SpoU_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00967">
        <property type="entry name" value="SpoU_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="alpha/beta knot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="RNA 2-O ribose methyltransferase substrate binding" evidence="11">
        <location>
            <begin position="152"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="42"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="435"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="44"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="54"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="79"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="90"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="103"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="120"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="442"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0012075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="493" mass="54307" checksum="A7F7A8FA6AFA03AC" modified="2023-09-13" version="1">MANLCKHITRQRGASCLTGTQTQFHRLGPSYQPIARYYKTGAESRGSSINNSRSSKDPFDRLSEDRGSGKFGRPMFGNRDSKYASRDSSRNGQSSSSSSNYPQRERDGSRDGFYDRESSSTRYSSPQQRSYNSEPPQKSEAPSQRISQNHDYLYSPNVVLPAMQNGFRTPYTLFYSSTVVQNRKKRKDDPVADCIKVAKEADIKVTKVTKHELNAMAGQRPHQGVVLEASKLSETIVTALGPVSTDNHYEIICKSRDARPFKSRDNEPPVWIALDEVVDPQNLGAIMRTALFMGVDGVIVCHKNSAPLSAVVAKASAGALEARPTYGESQKNGWNVVGAHVTYGSKRNRPIHEWPATGVDQPTLLIMGNEGFGLRKQIMNQCDTFIQIPPLSTTVSNVDSLNVSVATGIILSKLMGGRFLHLPKNLKKFPLRVGRITGSDKNDDDDGDNKENDSDNDDDDNDDDDDDDDDDGDDDDSEDGASKNPSGAKPLPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSL7</accession>
    <name>A0A9P6MSL7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_000876</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 37 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001195">
        <property type="protein sequence ID" value="KAG0011175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSL7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008107">
        <property type="term" value="F:galactoside 2-alpha-L-fucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042546">
        <property type="term" value="P:cell wall biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009969">
        <property type="term" value="P:xyloglucan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004938">
        <property type="entry name" value="XG_FTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31889">
        <property type="entry name" value="FUCOSYLTRANSFERASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31889:SF2">
        <property type="entry name" value="FUCOSYLTRANSFERASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03254">
        <property type="entry name" value="XG_FTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="89"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="123"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="150"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="178"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="45"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="693"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="713"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="739"/>
            <end position="755"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0011175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="847" mass="96013" checksum="B3E0B9704D645E79" modified="2023-09-13" version="1">MDTSTSSSRFSPTGTKHTNNNNNSSNNTILPVHSHYHNQYHERTHSPDLEAHGNRSKRLRTPSPPLLSERNTSSYLPSLNRRWTKKQPWLIAAALAVGIILPIWIFASGIITLDKFNDYIRYLPGYSIFANNLLYLVMFLLLISFTALSALPYFPIYMLGLPFHLLIFSIFNKLMNDWVWWCIGCYTILTLAPSLSLLLARLRISLDIAGSQQLYDIRGEVFGLRNKSSQNFSSALPPSPSPSLSFKYSPLRNLDSDFEAESKPNNLFKSAFTAFFSRLEYCAQLMSVSNRNSIRWRMLLALGLWLSYVIPVTLGNESRDFDPARSAPSFDIDHPEPLCSARVMQGIPPRYDSFEGYWQEYLQFHQQMVLPEEEGGVPEKDKRFLVFQPSDDGLGNRLQSLLSSVVMAMVTRRAIVLDWLAQPQCNANFTDLFQQPEGLQWDLNTTIPNYKEVPYYKKRPEIWYPYCRNCALRSPITPDSTWSDLLCNENLGINSSLPLVQIISTQWFLPVIQHNPYWRRELCHMFPQVSELNPEQNVGFGNAFEVLAKKLLKPSKAVQQKIDSVMDRIPEGVTLVGLQVRRTENNAVGKGIEDSFLSCAASVVEEEEEKAARESGSAWSSDLDDFSELKNDDIDDIDTDESDSTIALQGSTSFRKRYAYYLATDYRPTRAHFQRVLGDQLFVLENTFESQKDTQSLELSASDPDRNATENILGDEDIDIDGDNEFDSDSDSDPDSDSVNNQSATAPNSKQTEAVVRNSVQGVQTAVAEMFLLAQSNRIISSPYSTFGYFAHGYANIQPNIVKRDGQCIKRKSTQPCFQYWFGFANGGAKCSIKATIDMSEDYDCWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSX6</accession>
    <name>A0A9P6MSX6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">TATA-box-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">SPT15</name>
        <name evidence="7" type="ORF">BGZ80_000764</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001168">
        <property type="protein sequence ID" value="KAG0011329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSX6"/>
    <dbReference type="OrthoDB" id="2127950at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd04516">
        <property type="entry name" value="TBP_eukaryotes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.310.10:FF:000001">
        <property type="entry name" value="TATA-box-binding protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.310.10:FF:000002">
        <property type="entry name" value="TATA-box-binding protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.10">
        <property type="entry name" value="TATA-Binding Protein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00408">
        <property type="entry name" value="TATA_bind_prot_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000814">
        <property type="entry name" value="TBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030491">
        <property type="entry name" value="TBP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012295">
        <property type="entry name" value="TBP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033710">
        <property type="entry name" value="TBP_eukaryotic"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10126">
        <property type="entry name" value="TATA-BOX BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00352">
        <property type="entry name" value="TBP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00686">
        <property type="entry name" value="TIFACTORIID"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55945">
        <property type="entry name" value="TATA-box binding protein-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00351">
        <property type="entry name" value="TFIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0011329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="220" mass="24166" checksum="DC137A943B5A3ADC" modified="2023-09-13" version="1">MFAVPTISAPGSSNAAQPEKPASELTTEDQAAVDAPLHSVAGIVPTLQNIVATVNLDCRLDLKTIALHARNAEYNPKRFAAVIMRIREPKTTALIFASGKMVVTGAKSEDDSKLASRKYARIIQKLGFPAKFTDFKIQNIVGSCDVKFPIRLEGLAYAHGPFTSYEPELFPGLIYRMVKPKIVLLIFVSGKIVLTGAKVREEIYQAFEAIYPVLTEFRKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MSY1</accession>
    <name>A0A9P6MSY1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fungal lipase-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_000061</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001005">
        <property type="protein sequence ID" value="KAG0012301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MSY1"/>
    <dbReference type="OrthoDB" id="426718at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00519">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051218">
        <property type="entry name" value="Sec_MonoDiacylglyc_Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45856">
        <property type="entry name" value="ALPHA/BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45856:SF24">
        <property type="entry name" value="FUNGAL LIPASE-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="126"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="Fungal lipase-type" evidence="3">
        <location>
            <begin position="290"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="Fungal lipase-type" evidence="3">
        <location>
            <begin position="442"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0012301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="716" mass="80769" checksum="DFFA32A49857AD61" modified="2023-09-13" version="1">MTNAGEDPTAARAHRHGAFHLGLFSSKSRKLKQEQREQSAPKRYPFSHRYLDEFKVLKGYEKPSEEKPKPEAVGGRKPSMGVFKKPIEIQSTTFIGFISDGVALYISNLLHPSMIPGRDMVSRMYAMLVLPVLIIAMAIVQWGIGLLVILVNNTRIGAYYYGIFFNDQIALFDETDFVDPEGNDEALRQLASRKQRPKTHFSYHIANLLLIMSSMVYSRDEKKVAKASKMLLDIRNQAERDEASRLLRESEQSIDEDARREFGMRFMGISELKTLGGPYAGLFYNDDSIVLVYKGTSVLSFNEYLLDVTIQRVDASEYLYGEVHKGFYESLFPDPYPLNWYEDMTYDKTNPFKTIMQTIFETAKIGKQKTGKPVNLWITGHSLGGALAALTMARLQMTMKDTDPLLREDLNRSAKGLPGRKTVLQEMLARFSDDPDLLVLRDCYSVASPKVGDSTFAEEFGRNQALFCSESPYRSVYWRIVADKDVVPRLPPGCSVDPNEPGFHMTPCNVCLKSKSWLADEQDEDSKPSTVHKLTTLYSKYQKNPPKHLHTLLDYQHVGQLVEIFNAPKIPVVQPSTFEADLSHGVLRKKKEFYGFMSELAEIATSSPTPTTNGDANARQDRDQAVRQIADDIAKARALYDIDEMSRLRQPGILESAALMIPSLLSHAPAAYQRNLVRGRFHFTSFPGEEFEGRVGKWLDESAGGAVGNGVLRREE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MT06</accession>
    <name>A0A9P6MT06_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Methyltransferase small domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_011664</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000967">
        <property type="protein sequence ID" value="KAG0012553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MT06"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035657">
        <property type="term" value="C:eRF1 methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008276">
        <property type="term" value="F:protein methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052190">
        <property type="entry name" value="Euk-Arch_PrmC-MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007848">
        <property type="entry name" value="Small_mtfrase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45875">
        <property type="entry name" value="METHYLTRANSFERASE N6AMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45875:SF1">
        <property type="entry name" value="METHYLTRANSFERASE N6AMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05175">
        <property type="entry name" value="MTS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase small" evidence="4">
        <location>
            <begin position="39"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0012553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="231" mass="26171" checksum="9303B1D4BC277A15" modified="2023-09-13" version="1">MTMAINVDRQRWEESIALLIQKAQSHKDVYNTNINGFLVYIHPNVYSPKYFPESSWYARNLQKIVNGRSFLEVGVGSGIISMHVAKTGSTVYGVDVNPDAVDITRKNFEANSLEADVRLSDLYSSLDPETRVDFIFWNHPWQYSSAIVSELKSEKTFDEGYSALTRYIAEGHRYLNDGGAIMIGTSCYANLEAVDAIASKYGYQVLTEVQGIEKLEDGTEEVYYILRLKHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MU76</accession>
    <name>A0A9P6MU76_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_011420</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000916">
        <property type="protein sequence ID" value="KAG0012922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MU76"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048471">
        <property type="term" value="C:perinuclear region of cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006913">
        <property type="term" value="P:nucleocytoplasmic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027038">
        <property type="entry name" value="RanGap"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24113:SF12">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0012922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="149" mass="15362" checksum="83420A99B8179F4F" modified="2023-09-13" version="1" fragment="single">ALSEALKTDSTLTTLHLSSNKIGDIGAQALSEALKTNKTLTTLYLYNNSIGDNGAQALSEALKTGSTLTALNLSNNSVGDNGAQALSEALKTNSTLTTLNLTDNSTGFNGARVLSEALKTNSTLTTLYLGWTSAGIPSFNLRVSGSHPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUD4</accession>
    <name>A0A9P6MUD4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">N-alpha-acetyltransferase 50</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">NAA50</name>
        <name evidence="5" type="ORF">BGZ80_011303</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000896">
        <property type="protein sequence ID" value="KAG0013060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUD4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031415">
        <property type="term" value="C:NatA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007064">
        <property type="term" value="P:mitotic sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.30:FF:000006">
        <property type="entry name" value="Putative n-alpha-acetyltransferase 50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051556">
        <property type="entry name" value="N-term/lysine_N-AcTrnsfr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42919">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42919:SF8">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="4">
        <location>
            <begin position="28"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="7"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0013060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="184" mass="20519" checksum="E022FF57E7EB7214" modified="2023-09-13" version="1">MTPPAINMNSTASATTTGDKPKSSAFRIGLGDITVNNLGQIKRLNTVLFPVVYNSSFYKEILEVGEFAKIIYFNDVCVGGVCCRKEPIAGDKSSQNLYIATLGVLAPYRRLGLGSRLLTHILENAELTSSSEPKIGKVYLHVQKTNEEALEFYKKHGFQIAETLENYYPQFDDKDAYRLEKVLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUI7</accession>
    <name>A0A9P6MUI7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Pre-mRNA-processing factor 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">PRPF6</name>
        <name evidence="7" type="ORF">BGZ80_010976</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000827">
        <property type="protein sequence ID" value="KAG0013581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUI7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000244">
        <property type="term" value="P:spliceosomal tri-snRNP complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000256">
        <property type="entry name" value="Probable pre-mRNA splicing factor prp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003107">
        <property type="entry name" value="HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045075">
        <property type="entry name" value="Syf1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11246">
        <property type="entry name" value="PRE-MRNA SPLICING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11246:SF1">
        <property type="entry name" value="PRE-MRNA-PROCESSING FACTOR 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00386">
        <property type="entry name" value="HAT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="6">
        <location>
            <begin position="35"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0013581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="269" mass="30641" checksum="599B5D7F68597E5B" modified="2023-09-13" version="1">MKVWMKSAVLERQLGKIPEALQLLDQGLVKYPNADKLWMIRGQILVDRGDVQKARENYIKALKSCPKSVPLWILTSRLEEKVGALTKARALLDKARLLNPKTPELWLETVRVELRANNGNFGRAQMAKALQECPDSGLLWSESVWLETRAQRKGKIVDALKKSENSAHVLITAARLFWSDRQVEKARSWFLRSEKADDDLGDAWAWHYKFEIEHGDEARKKELVMRCKAAEPRHGEYWQAVAKDLKNAGKPLEEILVLVAASLPSNVVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUX8</accession>
    <name>A0A9P6MUX8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_011148</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000861">
        <property type="protein sequence ID" value="KAG0013337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUX8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="164"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0013337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="200" mass="22730" checksum="45AFCA623D2F8F2A" modified="2023-09-13" version="1">MSHHVLFKSLNLVTYITAISTIYYYREFIGDAILKHPNYLTNSEVGYVIPAINWFLLGGFNLVQWLDFAHDVVVEGVSWHLFVSNLIVASWRYNWLIAGQILLVINAILVWRLFIKVRVFTPTNLIDYAFVHISFSLYSGLVWLDVFQNFFAAFTNTESGPESLTAYGAAFSVFVLLAIGSYHAEFSRDPDSWSAATIAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVJ1</accession>
    <name>A0A9P6MVJ1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_009891</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000634">
        <property type="protein sequence ID" value="KAG0015376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVJ1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="314"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="389"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="50"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="243"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="22"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="328"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="400"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="449"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="470"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="487"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="507"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="577"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="588"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="612"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="633"/>
            <end position="642"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0015376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="730" mass="79940" checksum="DEC8230ACE245F8C" modified="2023-09-13" version="1">MSSTAAGRAARKTRREPIIESTKATQRSESPVITTDTPDASNASDHIKTIQLHKDEIEELTDAKARLEDKVTQLEERAQYLEATARLNASKVATEIVDLKEKARKLEIDLSTVVDERDALEQDIEQLKTQRQDAEVKDEARHLSIQLKDAWLKISTMKKSQEELVKKLFNSESASAQLQADLTKFQDLSAATKREHVDDINRWETERQEYIAEISSFKIASLKVKTTALSVQKTAPPEWILEKHQLVEQCATLQSRITTLESERANGGGLGDSGSKKLEADKLKLEKKVETLKAKLVEVMGHAMSIQAEAQEKIAKQDLSGKKSSNSQRRRSNARRRKRSPAMELESDDEVVVVVAEDESDIAQDVESINVAPTIRETRAKRIAAVKNVNYQILSSSSDQSDESEEDDEDNEDQEDDGDGDEDIDDDAEVGMDVEEQDGARDTEMQGVDNETASIDVNKTGPSIEHTESKGSPSSPQLDISSKDNIDDMNEETEPVQDDNTLSKSTSRSRKASVSKSKKATEGSSDSEFEPPKKTVIIKSRSRRNVKKSVSPSAEPAPKKTKITPVNKKRPNEGETPESTNNQSVPATKEKSTTVLRDTEHTTVDSMPDVQPSTSIASAATSSPAIAPNTPVDGEKPVSTEKVKKKRKLLTGKGLEELGDILNGPGSSFSSTPSTGLVFGKGKARLKSSSSTLPAGTTSNPANLEALNAIKMAFTLPKPRADLSAQDKEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVM6</accession>
    <name>A0A9P6MVM6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_009837</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000625">
        <property type="protein sequence ID" value="KAG0015479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MVM6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF147">
        <property type="entry name" value="CHOLINE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00623">
        <property type="entry name" value="GMC_OXRED_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0274">FAD</keyword>
    <keyword evidence="3 6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="7">
        <location>
            <begin position="90"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="354"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0015479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="580" mass="64628" checksum="85EE85B01CF86E8C" modified="2023-09-13" version="1">MVAATNGAHFDFIIVGGGTAGNTVAGRLAENPNVSILIVEAGVDNPSEIPEITTPSNAMNLRSSKYDWAYKTTMIKRDDYERIEKPNTRGKVLGGSSSLNYFTWIPGCKKTFDDWEEFGGKEWTWEPLLPYLRKSATYYDDEELYPSELKSIGAGGPLPISHAELIPEMKPFRDVLTRAWLSKGEELTEDIYNGKMNGLTHCVDTIYKGQRSGSFLFVKNKPNITILPSVHSKRLIIDASHTCKGVTVIAPSGDELSFYATREVILSQGVFESPKLLMLSGIGPKHELAKHGIELVLESRHVGQNLMDHPAVPFVLRVKDGFGMDDVLLRAGPRHTDAVSNYQKDKSGPVGSGCLEMVGFPRIDKMLEKDPIYCERKANNGGKDPFQPDGVRPHFELDFVCVFGSAFQWHYPVPKEGNYTSVVVDCVRTVSDPGEVTLNSSDPLIQPNINLNFFADDLDIIAMREGIRWTYDLLLNGDGFKDIVEKEYPWDMPLHSDEEMKRAVLERSQTAFHPTGTARLSKNIDQGVVDPQLRVHGINNLRVIDASVIPVIPDCRIQNSVYMVGEKGADMIKAHHKDLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVM8</accession>
    <name>A0A9P6MVM8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_010476</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000731">
        <property type="protein sequence ID" value="KAG0014393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2447618at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="297"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="556"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="633"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="740"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="907"/>
            <end position="971"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1041"/>
            <end position="1063"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1085"/>
            <end position="1154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1320"/>
            <end position="1365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1397"/>
            <end position="1449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1494"/>
            <end position="1554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="127"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="309"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="326"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="569"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="641"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="746"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="789"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1104"/>
            <end position="1115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1139"/>
            <end position="1149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1345"/>
            <end position="1361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1416"/>
            <end position="1430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1527"/>
            <end position="1536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1537"/>
            <end position="1554"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0014393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1554" mass="172421" checksum="F26DBA310B44836F" modified="2023-09-13" version="1">MTVYTYRIRNATMAPESVMELKDQQLVLDTSDYDEESAAMSIIEGSPEVQGVRERSRIGVENNTESRSNTNSSVYSTTNNRGSRINESTNGSSRESYSGNRTRKSKIGGNRGQLLIDPWLSTDVSVPGPDGDPSESSSGRDSPSRRDIEGSGRSRRASIGRSRFDHEPLILMSTSATTPGMLRDETPGPSFASPRKQLAGVIEINCSDQEEVEIDESQVQRRTMLDRGYSDKRKEDKNIEPLLASTVGQINRRRLVRSNSSLLSINVISSSDDERIQQPRTPIRRRRIAREILDSSDDDVDELSRDTGRNTLRSSTNRYRNSLHPVADDTIPRPSRPHEGSVELTSVVLPGSTAKMPWSITEGPDRDIVLSTPTSKQRIRHYNVILDSEDDFSETEESPDIWPVGERENSVLVRHLGLPQVDTVVGEEVRKSPSRAIVSDSEAEFGTADAASAEQNDIFIITQSTIGGRDETGAKAYVVESQDAYELPERSRISPDREAQKFRSVTKLRKPRPLVLDIPSDEYADYSPGRNLRSNDTKDIKEQDMKLRETLMFEDIPKDRTPSPAPEQLLRKKFDPKKEQTKSENSSFSFFPLFNRTTTHTQTKLQQEEPKVDEIKYRTLWKMKKETEDRRPLAQVSTVISEEEEEDEVLEDSRTRRHSGRARLVSPTKKIRLSEIAPDVAVMESALKAEAAHGRQQANGKGPCSLSRMETIESFSTLSDSQRTPHRMDSFTGHIISQAEEIEGFSDDHRSQMPERRQEERRIRRYSGLQLVSRDESKGPLDGAGVENPKLRLELSEDEKPQGSDQTSPDLHKDRGISPTLSEDTMERCPICRMMIPAKDLLDHVDAELLANEQREKEDMERRDEAMAYELNEIYQTQDAVVIRDSLPENEFVTQDPHHLRPLTQTKPFISADRRSLASPKKPVQSKDWCGKEVSLDTPTRKVGSLSLDDSPLTSKAIEQKRDQDTGFSFRPLHKIKSSSTVLSDDQLENEQDQEHDSFVLSEAESVSSQSAFKIQPGQIVINDTPPAASETTLNVGLASRKSTHAQNSHKASHKKKPESGDMLDPFVIQDEILDDDLDDFLDRPEPASMMSRPFRTNTNTNGKAVAKAVAPSRSSARRNSRVKVVNTSKKKPSKGMIELDDSSDEPDYDGDKNEDVMLASKRVTGAKGSKSKSTVLDGLLPTSVRQRRQYLLKKTRGQRNGNAIDVEDEIEIGRHHPPVVEKLWNQEDDLFDSEYLDPRQVKGVGLGGVVGGIGAIPGSLAMSKITKNTAAIAATTDFVSEIDTVSQRTSSRTVPKPNNIETSFEFEDTDYGLHSQDWWDNPQPADLGHSRENNRLGGYTSDQGSHRGFEEHGGQERLDDGYTSPLDDFIDLRERRDDPALAMYFAQFESDIGLANENTRGSRAGGRNRGRGRGRSSAGGSKASVGKKGISFGPGIGPMSTMKGASSQSAGPAAGQAVLTAYGIPRRAGSTMPASEGVSVDGHDRYGARKVSFGGHATTENGSMAIRSKPTQPFVPGKSKGRGKSGLKSYWSGRWAARRGRGGRGGRGRGRGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVU2</accession>
    <name>A0A9P6MVU2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">chitin synthase</fullName>
            <ecNumber evidence="2">2.4.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">CHS3_2</name>
        <name evidence="13" type="ORF">BGZ80_010585</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.16" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010000752">
        <property type="protein sequence ID" value="KAG0014199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030428">
        <property type="term" value="C:cell septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004100">
        <property type="term" value="F:chitin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006031">
        <property type="term" value="P:chitin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04190">
        <property type="entry name" value="Chitin_synth_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004835">
        <property type="entry name" value="Chitin_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054295">
        <property type="entry name" value="CHS4-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914:SF16">
        <property type="entry name" value="CHITIN SYNTHASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03142">
        <property type="entry name" value="Chitin_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22997">
        <property type="entry name" value="CHS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="174"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="431"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1024"/>
            <end position="1046"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1058"/>
            <end position="1078"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1085"/>
            <end position="1109"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin synthase 4-like" evidence="12">
        <location>
            <begin position="340"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="501"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1183"/>
            <end position="1227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1263"/>
            <end position="1341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="16"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="41"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="501"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="550"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="578"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1190"/>
            <end position="1200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1271"/>
            <end position="1290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1332"/>
            <end position="1341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF22997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0014199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1341" mass="147804" checksum="ADC832E3577105AE" modified="2023-09-13" version="1">MESGYQDLEAHRRTGANATDAPTNAEATRKPTGFKRQKSLVRPERERVDRNHPQYYYRNATQNLDGSNIRVQASSTGTDPTGAPVGRTGGVRRGKSVLGREPEKPGQPRLKAKEAAEKGTPFVDIKGKLKGKSREWPSKWVIYYNAVTCCFPPALLKSFGKHTAEIQRAWREKIALVSLILIMVMCVAFLTFGLQQALCRDNRSGKFVAGSRPLNVIISGMGYYFNAEKGKGVVWMHPAINKDISTDPVDIMNDATYGAKGMDASFLFQDNIGGECTNYITRATADTGNQANYYFPCVYRATDGSTAPNTTSDSTGVGCHSSAEDRSYWSTLSSSIIAPVYYNWDNITDPDRRFFAYDGDVIDADILKWIKPEFAVDDGISAIRNGSIPLQRDLSFYFARTKMTGLGKCLKQIARVGAMDSNTIGCMTSDVITYVSLVIILGVVLIKFFLAVFFGWFLSHRLGGFDNETYQDRIKRAEHIEMWSSDINRPAFNTKRQTFFPTTSRFTPSTPTGSSSVLASPSLGQPGARPLSTFNRPTSVFKPYTPPGSPSVNPAFLSTSNTSLNRASYFNQSLGPNGTPPPSPPPLPSSLRPSSVASFGGLRNLSRRSSTSSSTATQPTSCPLPLSPNAVVQPPASFQPFNFPLIHTMALVTCYSEGIDGLRTTLDSIATTDYPNSHKLIVVICDGMIIGAGNNMSTPDICLSMMQDDLIPRDEVTAHSYVAIADGTKRHNMAKVYAGFYKYDDETVPDKKLQKRVPMCLIVKVGGPTEQNQAKPGNRGKRDSQIILMGFLQHVMFDERMTSFEYELFNTIWRITGVAPDRYEIVLMVDADTKVYPDSLSRMIAAMAHDHEIMGLCGETKIANKTDSWVTMIQVFEYYISHHMSKAFESMFGGVTCLPGCFCMYRIKAPKGPNGYWVPILANPDIVEHYSENVVDTLHKKNLLLLGEDRYLSTLMLRTFPKRKMMFVPQAICKTVVPDTFKILLSQRRRWINSTIHNLLELVLVRDLCGTFCFSMQFVIFMELVGTVVLPAAISFTIYLCTISVYKAIWHNDSIPNTTVPLLLLAAILGLPAVLIVMTSRKMVYVGWMMVYLGSLFVWNFVLPAYAYWHFDDFSWGQTRMVAGEVAGGDHGAKEGQFDSSHITMKRWGEWECERRHKAAILAGLPAPQFQVTDSGEEWAGQVKEEGEMSDGSSGSRDSGQPFAVSRHLTQGSSGSGGMGYTLTDTGYPSAPGADSIPLLNMHVPTPGGTIGRQRVSQFNPDRMSAYIPPQTRQFTSPPKSSSNLATSNYTPPPPPPGARLGSVDTRAPSPMLVLAAQSGHAATNPGPIRQDSSESKSEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWE2</accession>
    <name>A0A9P6MWE2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_010086</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000666">
        <property type="protein sequence ID" value="KAG0015038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWE2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0015038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="227" mass="23602" checksum="213BFE882445FE4B" modified="2023-09-13" version="1">MRLQQVSYYQVIYNGVLAAQIVSFVPAQLATLLAVDPSKVVVLAIRDSSNSGTSKKRSLVTSNDQGDAILLTVAIPTSSYWALNSLVVNKSSSLYETSASSFGQYVDSTFPLSGSPPPNVSGSFGMNNPSVLNPLTGDEFGSQDPDTVTPGGNGSGTGTSSSSSNGALIGSLVGAATIAYVGIALVIVRRNRRKKEKKAEARFALQQSISAPIGVQGSEQGWGWHSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWM3</accession>
    <name>A0A9P6MWM3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_009918</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RING-type zinc finger family. LOG2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000638">
        <property type="protein sequence ID" value="KAG0015326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWM3"/>
    <dbReference type="OrthoDB" id="1711136at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16789">
        <property type="entry name" value="mRING-HC-C3HC5_MGRN1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045195">
        <property type="entry name" value="LOG2-like_mRING_C3HC5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045194">
        <property type="entry name" value="MGRN1/RNF157-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22996">
        <property type="entry name" value="MAHOGUNIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22996:SF0">
        <property type="entry name" value="RE60872P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13920">
        <property type="entry name" value="zf-C3HC4_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="4">
        <location>
            <begin position="747"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="179"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="252"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="415"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="584"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="648"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="31"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="431"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="448"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="584"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="605"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="662"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="674"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="691"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="717"/>
            <end position="732"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00025721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0015326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="842" mass="94518" checksum="E42DCD54D17D832B" modified="2023-09-13" version="1">MGAVTSSLQQSAHSRQQDGGRSRRRQRRRERRAERDYGGDVEARGEEYYSDEYDEDYDSLDDDDESEYSTPSRDRNDDDDGILEGEEACDSHPLYFGPAFHPVIEQSPAQLQLQRQIEQQLEQQQYRQQQQQLQIQQQQQRQNQQLSPLSTSGGQQLSLNDFILPSAISGLSGISAGGGIQGGGPGSGFPILSPPPSMLTTESAQDQLYRNSNLYNLISGLNVNPLLTEVQRAGTLDLSALEQELDDVEGGWMDIDDEDEHSRDQSNGNDTNIDYGHEGIVREMQPTKHSPTALACNINLKKSTLRIVKNFTVSNDPSIPAPSHLRPNYRLDFSFDSLTPCDVKLFWVVKEVEENGELGFRLRRLHHLPQPTTYHFPAGMNQRFISPILPLYTMSLPELTMQGLPSTSMRMFQKKKQRLWQQPNSTGKDFDDSEREWVDDGDNDVISRRNRKSKSNGRKKNKADKNGIQDLPFGEGYYKKLAAQYPMMEEEEYKHIMEDQYFPLVILIESTKEYKATAPVRSLPTPVADSPGLYLVDNQAISTFACFNISSEGGFEIKVMKQKVWINSTNYLIQEIYGFTDSVSSSAPSNTKNGVTNDNTATPQDKSKTHQSKVKDKRLSRPLSRLSRAESIASRVEELTMDRLTRKRSKAVISETPGGVNQDDKAGKNKDETLSSPRASNAGTVLDLDIAEPRNSDKEEDQQPQKSQEDSCDQDETTSKAGKEPEDDQAKAEEEEANLVLLDAPECVICLSDVKDTIVLPCRHFCICSECGDILRRRAPQRCPICRQVFQALLHIASSATRIPDFVDVDSPTSPSATAFPTPTEILVNEPSGNDGRYSMRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXG4</accession>
    <name>A0A9P6MXG4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Brefeldin A-inhibited guanine nucleotide-exchange protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ARFGEF1</name>
        <name evidence="8" type="ORF">BGZ80_009379</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasmic vesicle</location>
            <location evidence="5">COPI-coated vesicle membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000556">
        <property type="protein sequence ID" value="KAG0016190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030663">
        <property type="term" value="C:COPI-coated vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032012">
        <property type="term" value="P:regulation of ARF protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00171">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1000.11:FF:000003">
        <property type="entry name" value="Brefeldin A-inhibited guanine nucleotide-exchange protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.220.20:FF:000002">
        <property type="entry name" value="Brefeldin A-inhibited guanine nucleotide-exchange protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1000.11">
        <property type="entry name" value="Arf Nucleotide-binding Site Opener,domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032629">
        <property type="entry name" value="DCB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015403">
        <property type="entry name" value="Mon2/Sec7/BIG1-like_HDS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032691">
        <property type="entry name" value="Mon2/Sec7/BIG1-like_HUS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046455">
        <property type="entry name" value="Sec7/BIG1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023394">
        <property type="entry name" value="Sec7_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000904">
        <property type="entry name" value="Sec7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035999">
        <property type="entry name" value="Sec7_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663">
        <property type="entry name" value="GUANYL-NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663:SF375">
        <property type="entry name" value="LD29171P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20252">
        <property type="entry name" value="BIG2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16213">
        <property type="entry name" value="DCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01369">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09324">
        <property type="entry name" value="Sec7-like_HDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12783">
        <property type="entry name" value="Sec7-like_HUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00222">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48425">
        <property type="entry name" value="Sec7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50190">
        <property type="entry name" value="SEC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SEC7" evidence="7">
        <location>
            <begin position="790"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="38"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="376"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="689"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="761"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1468"/>
            <end position="1489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1670"/>
            <end position="1700"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1745"/>
            <end position="1789"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1953"/>
            <end position="1978"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="46"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="714"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="766"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1468"/>
            <end position="1488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1680"/>
            <end position="1700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1752"/>
            <end position="1765"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1963"/>
            <end position="1974"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="2005"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00060451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0016190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="2005" mass="221716" checksum="92EE4F274AB8E170" modified="2023-09-13" version="1" fragment="single">MSSLELALQRLLAEAHPRKERDLVEAAQGAMERIQAFKLSAAPSVPKQSISTTEQRTPTSSTDDPNHHPPSTPEPTIKASSSIEFDSLDAEEYWVVFKLACAPSVSNKVKVLALDALHKLIAHGKLSGNAPLILPPTTRPTPVPSTAVGRPKFATFSETNDLSHIDCSDPTDHLVPNLPGANTVGPDHYPDPPRLLDEIVHIVCMTYRGPGTVDDNVQLQIIKILLTVVTSTTCHVHHASLLKIIQTSCNIFCWAKSPILQATAKAGLTQMVNLVISTMETDAHVLRDVEKTLSKNSVVINQESSSDDGNDASLSATVELQDASVQSISVQIEEETNIETDETDQETLVIEAEAEAVTEVVAVTEAEIENEQQQVLDQVQEQEQEQESSPTNIPLPESPAPERAPSVNSAATVAPPVVEGQKELTPREAAIAACRVSRQDAYLTFRLLCKLSLRSDISPNNAQQEELSIRGRALVLELILSMMNNSGPVFQSDALFVGAVRQYLCVSLSQNGVSANETLFEFSLSLFLTVLQYYRAQLKAEVEVLFNEFYLKFLDMSNATMRQKEMVLQGLHKICSNPQSLVDIYLNFDCDFSMASIFEHIVNSLSRIAQGRGKANASTTVGNMMGKQLLLNEKDAWALIQDRRLAVQGLRCMVSVLDSLVDWSKDVGTVTQLSEAVASATAAAVAANNSANGQHTREASSSDLTATAVPPSPQQEIANTDSPTGSPFSRRSTQSPPGLYNKMSHPVIVSKNPLLAMSMRSQQNANSNVSSTSVNTVGSTDTLGDDHPAEFEEIMTRKQLFLKGVRLFNSKPLKGVDFLIKQGFVRDEYHSIAAYLMTTSSLDKAAIGEYIGDGEEKAIKVMHAFVDRLDFTGVGFVDALRMFLQTFRLPGESQKIDRLMEKFADRYCETNPKVFANADTAYTLAFSVIMLNTDQHSDSVKRRMDVSDFIKNNRGINDNSNLPDEYLAEIFHNISTNEIVLEEEQAREASKSNAASVGTIKQRQELYDMAISQMQKNARALLTGNEGRVKSTAAWRNATHAEHVKPMFAVACWPAMATLSLAFEEAIDPSIFASKTEPKSREFAAINAEAIDLCLRGISNAIRIASIFHMEVERDAFISSLAKLTGMNHVSEMQAKNVLAIRTLLKVANTMGEYLEGNWNLILNTISAMEQLQLIPHGGRVSTEGFNGVDYQHTASSNGAANSTSTQSSSKRKVSLSAMMNEFQSQDTIIAIDKIFANSITLSGDAIVHLFKSICAVSLAEVEGSRNAPRMYMLQRIIEIADYNMVRIRFEWTQIWRILQSYFNAVGCSSNATVSTFAIDSLRQLAMKFLARDELAHFNTQNELLRPFEHIYKNNPSTAIHDLIIQSLRQMITARASNIRSGWKPMFGVFGRTATHGSGALVENAFGIVQMIYDSSFDVIETSFVDYVNCLVEFCFNYDEKVVDGAMALLKKCARGLWLEARAASAAKEDNPNQEKHLTVGETQSKDAAEEEDEDTFFLKWFPIVYGLSRVVVDSELPSVRSKALVTLFEILNGSGEIFESQYWSKIYRVVLMPIFEDLKDPDYKRRDLTTTIWIQALRFMVNLYSRQYHQVFYAQTDFLKGLLELITLLVSKKSENLGQMGILCLNQLVTKNGAMFDEERWELVTYTLETIFDMTTPHEVMVIDTGASSSTQKTENGIAATDSAPTTPTTATSVATPTAATTTSKFDFQETVTKCAIHLVAITFVKEMALTDLSLWPASSSPYAAHHVSAPSGSHQQNQAQPSQGDREAAGGSRSPSISGAQGADQPGAIQAPAIKPRFLHNMPTGLRHRWLECLRKSYRFVRAFNDNYELRHYLYKSGQIQQMPNMFKQENLALTTYVSVLFDFYRQFGDGEGYDAEDEIQAVLEPLVQETKLIIARYLGMLSEPAKYPKDVIVNQSLLTIMVLRELQRTPIWWPNAAVILSADGTSPRLPSSSSSSSISNLANGTHQQSASEADKRKYHGLRKELPDYFRLAIRLVGVDRPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXU2</accession>
    <name>A0A9P6MXU2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">3-ketoacyl-CoA thiolase, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ACAA2</name>
        <name evidence="8" type="ORF">BGZ80_009122</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000521">
        <property type="protein sequence ID" value="KAG0016579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXU2"/>
    <dbReference type="OrthoDB" id="5404651at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003985">
        <property type="term" value="F:acetyl-CoA C-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.47.10:FF:000010">
        <property type="entry name" value="Acetyl-CoA acetyltransferase (Thiolase)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020615">
        <property type="entry name" value="Thiolase_acyl_enz_int_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020610">
        <property type="entry name" value="Thiolase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020613">
        <property type="entry name" value="Thiolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18919:SF107">
        <property type="entry name" value="ACETYL-COA ACETYLTRANSFERASE, CYTOSOLIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18919">
        <property type="entry name" value="ACETYL-COA C-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00098">
        <property type="entry name" value="THIOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00737">
        <property type="entry name" value="THIOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00099">
        <property type="entry name" value="THIOLASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase N-terminal" evidence="6">
        <location>
            <begin position="4"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase C-terminal" evidence="7">
        <location>
            <begin position="271"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="4">
        <location>
            <position position="88"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="350"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000429-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0016579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="394" mass="41286" checksum="1958723CCD19EB19" modified="2023-09-13" version="1">MANVFIVAARRTPFGAFGGKLKDYTAEELGAFASKAALTDLGKEVPIDSVIVGNVAHTDAAGPYLARHVGLRAGLDITVPALTVNRLCGSGFQSIINAAQEIKVGDANIVLTGGAESMSLSPYALRNIRFGGTRFGIDLKLEDTLAAALVDRYPKECPMGITAENLAKEHNISRQDCDEYALSSQKRWAAANEAGRFKAEIAPVEYKVKKAVETLSHDEHARPSTTIESLAKLPSVFKKEGTVTAGNASGISDGAGAVIVASEQAVKEHGLKPLAKVVSWHVTAVEPSIMGIGPVTAIQGALKKAGLALKDMDLVEVNEAFAAQYLAVEKVLGLDRNKTNLDGGAIALGHPLGASGSRIMAHLTHELQRTQGKYAIGSACIGGGQGIAIIVERC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXU3</accession>
    <name>A0A9P6MXU3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CsbD-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_007780</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0337 (CsbD) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000404">
        <property type="protein sequence ID" value="KAG0017916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXU3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1470.10">
        <property type="entry name" value="YjbJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008462">
        <property type="entry name" value="CsbD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036629">
        <property type="entry name" value="YjbJ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05532">
        <property type="entry name" value="CsbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69047">
        <property type="entry name" value="Hypothetical protein YjbJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CsbD-like" evidence="3">
        <location>
            <begin position="55"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="59"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="65"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="80"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0017916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="97" mass="10014" checksum="1A6AD0C35B094192" modified="2023-09-13" version="1">MSNVTDRVYNTANSYIGGAKQTVGETLGYPDLAARGAEQKARADSAQAIAAAQTQVEGAGHQMQGKAQQTVGSITNDPSLEARGHANEVRGNVEGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXV7</accession>
    <name>A0A9P6MXV7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Heme oxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">HMX1</name>
        <name evidence="7" type="ORF">BGZ80_008036</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000424">
        <property type="protein sequence ID" value="KAG0017677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXV7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004392">
        <property type="term" value="F:heme oxygenase (decyclizing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006788">
        <property type="term" value="P:heme oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19165">
        <property type="entry name" value="HemeO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.910.10">
        <property type="entry name" value="Heme oxygenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002051">
        <property type="entry name" value="Haem_Oase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016053">
        <property type="entry name" value="Haem_Oase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016084">
        <property type="entry name" value="Haem_Oase-like_multi-hlx"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10720">
        <property type="entry name" value="HEME OXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10720:SF0">
        <property type="entry name" value="HEME OXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01126">
        <property type="entry name" value="Heme_oxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000343">
        <property type="entry name" value="Haem_Oase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00088">
        <property type="entry name" value="HAEMOXYGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48613">
        <property type="entry name" value="Heme oxygenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="129"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="252"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000343-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000343-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0017677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="289" mass="32952" checksum="ECD763149B058ED5" modified="2023-09-13" version="1">MTSNAKETPLLLTDELRLKTKGLHSKMDRLVQLGLFAVLDYKVYRQILLGFYYVFKTFEEEYQLQLEKSPVNMSLLSAHSPELRRTEAFEADLAYFYGPQWKEQVKPTEHVQAYMDHIRDIAKNKPEKLIAFPATLYLGIFFGGQIVRSKIVKAINFFPSPPEKKMGGESDNCIAIFTFRERDPSTGHASGKRLDPNNAKNMLKARLNNIPGINDQTADSIAAREAIAEEAKEIFVRNLDLITSAEGVWSVWVRWIFTFVLYAAVAFGIYQYVVLQFNGGNSANKEHEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MY21</accession>
    <name>A0A9P6MY21_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ribosomal 40S subunit protein S18B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">RPS18_2</name>
        <name evidence="7" type="ORF">BGZ80_007517</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the universal ribosomal protein uS13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000387">
        <property type="protein sequence ID" value="KAG0018130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MY21"/>
    <dbReference type="OrthoDB" id="5534642at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.50:FF:000002">
        <property type="entry name" value="40S ribosomal protein S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.910.10:FF:000002">
        <property type="entry name" value="40S ribosomal protein S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.910.10">
        <property type="entry name" value="30s ribosomal protein s13, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01315">
        <property type="entry name" value="Ribosomal_uS13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027437">
        <property type="entry name" value="Rbsml_uS13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001892">
        <property type="entry name" value="Ribosomal_uS13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010979">
        <property type="entry name" value="Ribosomal_uS13-like_H2TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018269">
        <property type="entry name" value="Ribosomal_uS13_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003140">
        <property type="entry name" value="PRK04053.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10871">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S13/40S RIBOSOMAL PROTEIN S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10871:SF3">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00416">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002134">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46946">
        <property type="entry name" value="S13-like H2TH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00646">
        <property type="entry name" value="RIBOSOMAL_S13_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50159">
        <property type="entry name" value="RIBOSOMAL_S13_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0018130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="163" mass="18890" checksum="BFBCE01713221236" modified="2023-09-13" version="1">MDGMGCNKDLSLLVPEKGQFQHILRVLNTNVEGKNKIMFAMTNIKGVGRRYANLVCKKADIDLKKRAGELTNEELERLVTIMQNPTQYKVPQWFLNRQKNFVDGKYTQLLANGLDNQMREDLERLKKIRAHRGLRHYWGVRVRGQHTKTTGRRGRVVGVSKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MY52</accession>
    <name>A0A9P6MY52_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008457</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000459">
        <property type="protein sequence ID" value="KAG0017271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MY52"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="305"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="345"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="37"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="259"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="276"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="363"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0017271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="435" mass="46584" checksum="E9EC2BB297EF8150" modified="2023-09-13" version="1">MSTLSAMNITSPWSSAKDFYHLKRRNTRGKKDHSRSSSRPLSSPASPFTDNLASKNSTYPEDDLLLIDPSSAKQSTRLEDSKCTEPYRSFNDTEKSSQPTNVPSWFGSLRSFAVSANSSSRGAFAPLGSLKTDPSISSRPHCRGRSSSIYYAGCLDGDDDDSDRECTLDEPITEKNGLKENRVRGPRRSWAMLDPSLGGFFPSSHKAVPGSDGELPSPTCSSSASPLHSPTFDVEGATISEAPYRDDDNRHDARGGGSSRTESNNALSNYEGHSNTATTAYPTSSAPSPTTSAFSLIKSYVPSLPSFQDSSSGSGGAQQTGAESSGSTGGFWSIRKLSLNLLSSSNQHASTENLLEDVQNESVEDRHENLYRDDGDSEETATPTSPSVSYFSSILGSATSTVGSKGSQLLSTQVRDNLEQLPVSSKSIMKIGRTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYF1</accession>
    <name>A0A9P6MYF1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Chromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_008521</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000464">
        <property type="protein sequence ID" value="KAG0017218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051219">
        <property type="entry name" value="Heterochromatin_chromo-domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22812">
        <property type="entry name" value="CHROMOBOX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromo" evidence="4">
        <location>
            <begin position="829"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="183"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="798"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="883"/>
            <end position="1044"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1188"/>
            <end position="1335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1473"/>
            <end position="1504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1625"/>
            <end position="1699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="189"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="201"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="886"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="911"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="930"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="963"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1020"/>
            <end position="1029"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1033"/>
            <end position="1044"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1202"/>
            <end position="1211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1212"/>
            <end position="1233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1245"/>
            <end position="1256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1278"/>
            <end position="1295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="1304"/>
            <end position="1316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1490"/>
            <end position="1504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1625"/>
            <end position="1646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1647"/>
            <end position="1668"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1669"/>
            <end position="1699"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1699"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0017218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1699" mass="188653" checksum="C67D19485EFF2AD1" modified="2023-09-13" version="1" fragment="single">SFGIIIIARGTAESPGHLSSVNNVISTRRTSAVSEDKDPKKSKTLFLQDEDRIDQALAFRQDEAENSKPKVKAKTKSKIKTLATSTAKTRKLAIMRHLAYHHPTSSLKVGTLAANIKRAVPNDGVLQQKITHCIRDAVHEAARIKRESQRVIGKFIQYVDKHGLGPSDRRFLDLLCPRVSMEDVKDQKDEEAEEEGEEDENRGNDLNDKPKSSFMACMYSGNRPRNSGISSAVIEFIDRLHHLKTYTPPPPSSDGCRHKTAFTPTELVQSVSTQLRVELKKMYKNGSCDLYKMLMTRKKKSLLGTDANVTIQDEVSAVENYLVFNKISPNSRRIIPMTGSEQPFVSFTGHQLAESFFSHGGILRTRVQELVGTVCTSIVDAQEYVAEKEPGHFTKHFLADIDLKGLTSRQRRKAGHRGVIELPSFAEYEAHLNMLNSRDFKPETYLTKKYVPRGTIRTDGFHLQPLWFKRRELLSVKFKRIPDDRLPPRLTTTFHGTGDNLTEIRNVIKTQKDVAELWPNADPRDIKILTLDAGKALVVGVYAHLPQASEDKDPEHRATSTFETPSFVVSATMPLAPPPPPPPQDSIQSQISLANYNKTPHHNLAVNQKAVMQPVFRYRRWLEEAKKVTPEGRSEPVAKIESQLPPLRGAEASVSNHIARLEQVENQLLEFYNGSNNKFKKNTWDAERAKHIEYQVIANSLLKSVGGSLGERCKDPVLIGVGLGNFGSSGRLSSLHTTDIMAGENMSKIVQNYLLNQERPLYLQPKTANGRYPWKESSGSEQGIAVGTSKSIAQMPNPAQIDCHRGNSNRASQNRESETMSESIIQDLCLVEKILQKRIDTETGVVEYLIRWQGTDAQGNEYEDTWEPEQNILGDELIEEFERKQASKRPQRQRSPGRPKGSLRDAGELGQETTQKGQTSSQYLGPAEPVSQSMGSRQPPQQPGMAHPLDQHPPPPPPLGYFHSSPYSPHYNHPHYPTPPRQPLITGPSPYNTRTKRKLPSTSNNDQETTEATSEAASVAQGNSNQESASMEGVKRQKEGNSLRSQIHADKYVRRRQISSTSGATAETMRLLKLHFDNEKAYFISIIEKSTLVKDANVRSEMVRFLKDPRYPGLPQGAKLLESETWLIELKQQMGSSGSLFLALDIPRGEVKALFIPEWMLEHQRKAHPDQGIVLKDRTVVSAIMEGDLHGSGLYPPEATEGQESQRSSVDASSAPTSGAQQSQQSSVTVSAPTEKEVSRQSPDTTTTAATPAAEVVKAKETQQSSDSTPLAVANSANDKERPSHPIDQGLRREQVPPVSSPSSSPPPSPPSPTPASPAHQVETDGDITMEGTPENLANSIQSPLLHCEWKNCQQARATLDELSKHVLQDHLQGLLASSSLAPTTPPVNVETAASALAEGSSWQARYELSQATYRSLQDQIARTKDIALKVDQKIQESRILYTSAVAKSKENIKRLEAHLEWEMKKWNKYQEQKSQMAARLTDPDGSPESQRKGDVNADSNAKRTESSLLDFEAVKLDKPMEAQSINTIRDIQRTLAAAKQDLARMEEDNLALFEKRRTLDTELKSLDERFQQTIAQLAELKAKEHTTREEIKSRSQSIEECKATMEQEQAKAREVLSQLQSLIETMKQSGQQQHTFTNGQESKNPSTSSVAAASSSSSASTPSHSISQQPDSTGDLQATDPAPSNITSNTTDSLDLKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYV7</accession>
    <name>A0A9P6MYV7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008004</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000421">
        <property type="protein sequence ID" value="KAG0017711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYV7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="296"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="328"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="349"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0017711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="430" mass="49009" checksum="6F274D3873F05C1D" modified="2023-09-13" version="1">MTPNKSNKQKKQKDGERQEEKENQPLRKKNKGKKEDEDMEEEKKRSRFSNSHFEIILDFLERPRKYDEVSNIGKRGDGGKSREKAFAELTEYFKERIRHKPALAKSLRWESLTPTDMMNRWDYINKKYKKPATGDGYYSACPASAKDAEVEREIGDRVRAIVHKSPTNNPHATKTVGGLPPRLPSNGHASDPQANAFVDANDVSLEEEEDEEEEILLRHTAAAYSLAVEDPDEDYILLSDSLEDEAKRGKMKALSSGSREDGSHDSSLEVGSSSQEGKKKGKDKAARHWSEIQSAGEEDELSHEDDALEHEDQDDAPIPDIGPSTQRSKGKKVQRGMKIRRRNDCQVESASQYSKRSSRSGSTVERNFALYTEQKLRLQETECSERLKIRRMEANDRQRLTDVIERSTVATEMMVKQVMETQAMLLAFVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYV9</accession>
    <name>A0A9P6MYV9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007333</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000373">
        <property type="protein sequence ID" value="KAG0018313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYV9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0018313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="322" mass="37561" checksum="84F30FC201431885" modified="2023-09-13" version="1">MSEQCNDTAISQEVAPQSSPFQQPSPRIPYECLYYVVDYLHDDFDTLKSLLYANKFFFHAVLPHFIRDPHSNPAMSRKWRNHWTTHEKFLALILTSFLEARLKEFKIPPEAGELAELGISKITEHFGLQLVKPFTIPGHQMLRSFLKRIDDKSNTHQNSGGDDLKGIEPTMTTDYSKFVADIPRFDEIPIRAYLMIRLCKLPAKMRAGRIQHPQKVDDKVEEHTLSQQRDHRYKEELYNSLTKLWDHFNRQHILSYSLDMTLAQNFLSFSKEMAKLQTLRLDRPLDMTDSHGKHCFVHQAESGGIPTEAPIEYRIRQQLGYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYX0</accession>
    <name>A0A9P6MYX0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_006315</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000311">
        <property type="protein sequence ID" value="KAG0019092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYX0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0019092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="229" mass="25792" checksum="325C6346959DB18D" modified="2023-09-13" version="1">MINRAEVKLIDLPGLYEPRNNADTKKNAGILQEALSRGYEYKLYFVLKGDSRGPDDAELAMMSRVSQCVKEVDGAHVTFRVIVNLIPTRDVYEMYKSKLANDNFKSFFSQLEKSPESHQFRFDIIIDRVQLISCCESAIANRTLKDQIAQDVETHKQTLLSVGELKASNEDLRILKKVLLALSAPILLAGEIATGVLNGTSWFIGQIARVTSVSRQGTKAFREEFFDKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZK0</accession>
    <name>A0A9P6MZK0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Choline/ethanolaminephosphotransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_007409</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000379">
        <property type="protein sequence ID" value="KAG0018234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZK0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016780">
        <property type="term" value="F:phosphotransferase activity, for other substituted phosphate groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048254">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014472">
        <property type="entry name" value="CHOPT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10414:SF37">
        <property type="entry name" value="BB IN A BOXCAR, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10414">
        <property type="entry name" value="ETHANOLAMINEPHOSPHOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015665">
        <property type="entry name" value="CHOPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="82"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="180"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="220"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="254"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="288"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="319"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="351"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0018234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="393" mass="43647" checksum="15C136CD3135EFA8" modified="2023-09-13" version="1">MGNRYIPAEYRPNLSKYKYSGVDDSLLSKYVLGPYWAKLVTFFPITMAPNSITGLGLLCVVFNVLTMYYYTPDMTGVCPSWAYISFGIGLFVYQSLDAIDGKQARRTGTSGPLGELFDHGCDALNTSLEVILTANAMQLSESWWTVLSHFLALGNFYLSTWEEYHTGTLYLSAFSGPVEGILMIVILFLITGFAGPEIWLRTVRGTLGLPSDFLPSIPDVQINHCLVAVGILSMGGNILTALQHVVKARKEKKLSTAPALVGLVPFIGMSVVAYLWLDASPEIVYQHLLPWILYIGLSFGYSVGLMITAHVTHQPFPMFNIAFLPLIFGAFNANLPLLGFERLFGSHMENIYLWCCLAFSAVAYAHFAVTVVNDLCDYFDIWCFTIKHPKKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZR7</accession>
    <name>A0A9P6MZR7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_005047</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000251">
        <property type="protein sequence ID" value="KAG0019935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZR7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050248">
        <property type="entry name" value="Polysacc_deacetylase_ArnD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10587:SF133">
        <property type="entry name" value="CHITIN DEACETYLASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10587">
        <property type="entry name" value="GLYCOSYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="168"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="207"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0019935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="229" mass="25162" checksum="8CBF618C3182288B" modified="2023-09-13" version="1">MTDDHVKDDIARNSRTIQDLIGVYPKYMKIHEANLKDPRLLDIASSLGYTLVGFNLDEYDYKYNSVATSGQIAEASYVIAGHDVPSTGATAALPKVINTINAHSYDMVRLDGCTNDKTPYKKDPIENNGYVGDAQSLQTTSMDRIVLRQSTTHHPTTTTTTTTTTTTMLMTLVLLILLAVRMVPYARGWKGGWKNANGNGRELKKFGISKLAITPVLTVIPAAIYSFSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZW1</accession>
    <name>A0A9P6MZW1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UDP-glucose 6-dehydrogenase</fullName>
            <ecNumber evidence="2">1.1.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">UGD1_2</name>
        <name evidence="5" type="ORF">BGZ80_004919</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>UDP-alpha-D-glucose + 2 NAD(+) + H2O = UDP-alpha-D-glucuronate + 2 NADH + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:23596"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58052"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="1.1.1.22"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Nucleotide-sugar biosynthesis; UDP-alpha-D-glucuronate biosynthesis; UDP-alpha-D-glucuronate from UDP-alpha-D-glucose: step 1/1.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.22" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010000246">
        <property type="protein sequence ID" value="KAG0020008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZW1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003979">
        <property type="term" value="F:UDP-glucose 6-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006024">
        <property type="term" value="P:glycosaminoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000114">
        <property type="entry name" value="UDP-glucose 6-dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014027">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036220">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014026">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028356">
        <property type="entry name" value="UDPglc_DH_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11374:SF3">
        <property type="entry name" value="UDP-GLUCOSE 6-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11374">
        <property type="entry name" value="UDP-GLUCOSE DEHYDROGENASE/UDP-MANNAC DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00984">
        <property type="entry name" value="UDPG_MGDP_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03720">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00984">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52413">
        <property type="entry name" value="UDP-glucose/GDP-mannose dehydrogenase C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDP-glucose/GDP-mannose dehydrogenase C-terminal" evidence="4">
        <location>
            <begin position="68"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00047473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0020008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="203" mass="22957" checksum="148DE392B5551EC9" modified="2023-09-13" version="1" fragment="single">FLKASVGFGGSCFQKDILNLVYLSEQLHLPEVAAYWKSVVTMNEYQKQRFTHRIVRTLFNTVTNKRIALLGFAFKKDTGDTRESAAITLCSYLIQERANVAVYDPKVSAKQIKMDLTEPGVGTNEAEVDKHIQICKSAYEACEGAAAIVICTEWDEFKMHQLDYQKIFDSMQKPAFIFDGRLILDAAKLRDIGFRVETIGKSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N075</accession>
    <name>A0A9P6N075_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ribosomal protein S15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_005839</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000288">
        <property type="protein sequence ID" value="KAG0019414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N075"/>
    <dbReference type="OrthoDB" id="441444at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00353">
        <property type="entry name" value="Ribosomal_S15p_S13e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.10">
        <property type="entry name" value="S15/NS1, RNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01343_B">
        <property type="entry name" value="Ribosomal_uS15_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000589">
        <property type="entry name" value="Ribosomal_uS15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005290">
        <property type="entry name" value="Ribosomal_uS15_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009068">
        <property type="entry name" value="uS15_NS1_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00952">
        <property type="entry name" value="S15_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23321">
        <property type="entry name" value="RIBOSOMAL PROTEIN S15, BACTERIAL AND ORGANELLAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23321:SF26">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US15M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00312">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01387">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47060">
        <property type="entry name" value="S15/NS1 RNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00362">
        <property type="entry name" value="RIBOSOMAL_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="93"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="108"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0019414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="298" mass="33545" checksum="8F39D95BF5F5A686" modified="2023-09-13" version="1">MFGLRTALPGTRSLVASTKAAPCSSFHTSASALARPRRSRKDIVIQVRKNNIQKQEKKRLEFEGSTPDYIIGKDTDFTRSLLKQSILQTPLAAIKPADAPTSTSESDSTSGLRSSFSPLSPSIFSSSSRTPLVVSTSKPSGYQHFLNEAEADLIFEKVPEVQVQELMLQSALVSEKLQLPIERQKAELVRRITALENGNAKQITLENIRRAREAFQREEGDTGSPEVQAAIMTVRILNLNNHVLNNKKDKHNYRRLRMLVHQRQTVLKYLKKTDPERYHSCLNRLGLEPRSIEDEIVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0K5</accession>
    <name>A0A9P6N0K5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004651</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000235">
        <property type="protein sequence ID" value="KAG0020178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0K5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0020178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="84" mass="9412" checksum="56E048B6B6F452C7" modified="2023-09-13" version="1">MFNIHQGVKKPAVEVMVIQPLKVRAYFRQILYGTKCSREADSQFSEFWKDQSIIIITAITAITIGIIASSQKTIVVGMELHESG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1B9</accession>
    <name>A0A9P6N1B9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Amino acid transporter transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_004626</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000234">
        <property type="protein sequence ID" value="KAG0020188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1B9"/>
    <dbReference type="OrthoDB" id="40134at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF692">
        <property type="entry name" value="TRANSMEMBRANE AMINO ACID TRANSPORTER FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="64"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="119"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="153"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="177"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="231"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="262"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="305"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="346"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="376"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="408"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="9">
        <location>
            <begin position="35"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0020188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="442" mass="47766" checksum="34D6E6646462EEC7" modified="2023-09-13" version="1">MSKSEHVPEKLHEVDVESVSSGSLGDAYANAPAGKATNFQAYVNVVSVLAGAGTLGLPSALSDAGWVGLIILALASAMAIYSNQKLIKCLYYDGRTRLREYPDIAQAAFGLPGRIVVAFFYNSIALGGPVLYLILTGTNIYDLASSVGCNITIKQWIIIAAAVMVVPIILTKTMREVAFLSVFGALSTTIVVVIVMISSIINSKDIGLVTKPNGNLEPIHHDIAVPRNLPLALATFAFSYGGNVIFPHVEESMKNKRAWNKIILWGTLTVTLLYFMCSASGYAVYGDIVQSPIYLNLPGGATRTISTIIITLHVLLAIPLFLTTFNLQVESALKLESRSFSSRAEFLYRAIIRTLSMVLVATIALFFPYFGQMMSLLGALSDGMLTFVFPVVFYLKLFGFKKVHKLELFVMLLVILVGTAGAAVGTVDAIKELAKAYRGELN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1W3</accession>
    <name>A0A9P6N1W3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GMP synthase [glutamine-hydrolyzing]</fullName>
            <ecNumber evidence="2">6.3.5.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Glutamine amidotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">GUA1_2</name>
        <name evidence="12" type="ORF">BGZ80_001166</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; GMP biosynthesis; GMP from XMP (L-Gln route): step 1/1.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.2" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010000126">
        <property type="protein sequence ID" value="KAG0022061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1W3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003921">
        <property type="term" value="F:GMP synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01997">
        <property type="entry name" value="GMP_synthase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.10:FF:000002">
        <property type="entry name" value="GMP synthase [glutamine-hydrolyzing]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001674">
        <property type="entry name" value="GMP_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025777">
        <property type="entry name" value="GMPS_ATP_PPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00884">
        <property type="entry name" value="guaA_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11922:SF2">
        <property type="entry name" value="GMP SYNTHASE [GLUTAMINE-HYDROLYZING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11922">
        <property type="entry name" value="GMP SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00958">
        <property type="entry name" value="GMP_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54810">
        <property type="entry name" value="GMP synthetase C-terminal dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51553">
        <property type="entry name" value="GMPS_ATP_PPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 10" id="KW-0332">GMP biosynthesis</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 10" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GMPS ATP-PPase" evidence="11">
        <location>
            <begin position="1"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0022061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="269" mass="30035" checksum="B4BB6FAF4A99DDCC" modified="2023-09-13" version="1">MRHNECADAKKMLVDKMGINLKIADASDRFLANLAGKTDPEQKRKIIGNTFIDVFEEEAKAIDDACAATGGQPIEFLLQGTLYPDVIESISFKGPSATIKTHHNVGGLKENMKLKLIEPLRELFKDEVRELGRLLGMDDELVWRHPFPGPGIAIRILGEVTKDQVAIARKADYIYIEEIKKAGLYRQIAQAYAALLPVKAVGVKGDKRTYEQMICLRAVETSDFMTADWFDFPAPLLKKISSRICNEVEGVNRVVYDISSKPPATIELE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1X0</accession>
    <name>A0A9P6N1X0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Pre-mRNA-splicing factor 38</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_000956</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Required for pre-mRNA splicing.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the PRP38 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000121">
        <property type="protein sequence ID" value="KAG0022143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1X0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005037">
        <property type="entry name" value="PRP38"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23142">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR 38A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03371">
        <property type="entry name" value="PRP38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5 7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0747">Spliceosome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0022143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="322" mass="35129" checksum="48A37BEBF22015BF" modified="2023-09-13" version="1">MAMDNKTVRDAIQIHGTDPQFLIEKILRTRIYESTYWKEHCFGLTESTIIEKAYELTYIGGQYGIQKPTEFICLVLKLLQIQPREEIVIKYITGLNESDNNKYLRALGAFYLRLVGKPVDIYNYLEPLLDDSRKLRKRGAGGYSIIHMDEFIDDLLREERVCDVVLPRLVKRYVLEDAGELDPRVSTLEKLEMELEEERKAEEAAARGEDRALQVAVAAVAVVAVVVALQGTLKGTYQNQGPEAEAGAGAGAGAGAGAGVGVGAGAEAVGVEVEAEVEAEAEVEALTGRGVPTVPGVAAGAVVEAERENESMVLNNWCFILA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N239</accession>
    <name>A0A9P6N239_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">SnoRNA-binding rRNA-processing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">UTP15</name>
        <name evidence="9" type="ORF">BGZ80_003244</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000185">
        <property type="protein sequence ID" value="KAG0020989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N239"/>
    <dbReference type="OrthoDB" id="431715at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045943">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:001192">
        <property type="entry name" value="Protein SLOW WALKER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018983">
        <property type="entry name" value="U3_snoRNA-assocProt_15_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19924:SF26">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 15 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19924">
        <property type="entry name" value="UTP15 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 15 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09384">
        <property type="entry name" value="UTP15_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="3 6" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="119"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="161"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="245"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="U3 small nucleolar RNA-associated protein 15 C-terminal" evidence="8">
        <location>
            <begin position="352"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="514"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF09384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0020989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="555" mass="61176" checksum="32E906186225ECED" modified="2023-09-13" version="1">MSTDFKALTVKKYPRLPGRKTSESRYWRKFKSPIVVKEFAAVSSIHFSETSPYDFAVTASTRVQIYSSKTHQVKKTISRFKDVAYSGTIRADGRLVVAGDATGLIQIFDVGSRAILRTFRDHRHPVHVAKFSSDKTQILSASDDKTVRIWDMPSETPLTIFTGHDDYIRTGMVSHDNPHLILSGSYDQTVKLWDMRTQGCVMTMNHGAPVECVEMFPDGGVVVAAGGPFLKVFDILAGGRPMHSLSNHQKTVTSMCFDHSHSRLLTGSLDQHVKVYNVQDYSVVHSVKYPAPVMSVALSPDDTHLVAGMAGGLLSIRQRVVKTAEVQTRRAQEEQIRGGSYKYFVRGQKAAGEGDFTVESQKKRRLREYDRYLKAFQYGNALDACLRTNQPAVTTVSLIQELVHRDGLRQALSGRDDISLEPLAQFLVRNINNPRYTSLLVDVTMIMIDMYTAVLGQSPLIDELFMRLRAKVKLEIAFQKQLLSVVGSMEMLFAKSTSTSVGIAAHNELASTSNGAGNNGASNGGVVHAKSSSSSTSETALSSSLSTIQSSTKAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2U8</accession>
    <name>A0A9P6N2U8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001867</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000144">
        <property type="protein sequence ID" value="KAG0021703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N2U8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070939">
        <property type="term" value="C:Dsl1/NZR complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060628">
        <property type="term" value="P:regulation of ER to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.670">
        <property type="entry name" value="Dsl1p vesicle tethering complex, Tip20p subunit, domain D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042044">
        <property type="entry name" value="EXOC6PINT-1/Sec15/Tip20_C_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007528">
        <property type="entry name" value="RINT1_Tip20"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13520:SF0">
        <property type="entry name" value="RAD50-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13520">
        <property type="entry name" value="RAD50-INTERACTING PROTEIN 1 RINT-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04437">
        <property type="entry name" value="RINT1_TIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51386">
        <property type="entry name" value="RINT1_TIP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="211"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0021703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="482" mass="55449" checksum="5F9AA5DBFC268DF0" modified="2023-09-13" version="1">MLSSPEILSHAIHEALRFDKTLREVEYYMPPGQTKDWQGTVQIYLGNREWLKTWLRVEKEFAVARYTQIMEDTDAWQPAYEDMGDKALVVPTKSAEKLLDLLEIITDRYRPLPALEHKSFMLDIQLDLLLEYHHHIRSLVDQYESMTYSFVRVMPGTASAEEMSTMGIDGLRNLCCWMSSVEYVGSSLKDWGEDVLFLELYKETSERTRKISNPLHSDNEDSDEDSPRKKYNENGTIFDEPVRAFDVMSKRIQGLIVRNITNDVFGSLKPYASLRSWPQIEFSTPENSGRQPQNPLDSLENDDVSPELYQPLTLLTHSLEFLFGALSTKHFTLLYKQVSSEMQDFFWQKIIMKNSFSELGGLQLARDFRIGLLGAGRRWIKKPENYHRKLRDAVVLLSLQSTRANPAAPPPTVSFDQDLKKEGGGSGIQYAKKTLAQIMAVLFDDDLEVEFVEGKLEEIGVLSLNVPEAKSVIRRRVECWRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3F1</accession>
    <name>A0A9P6N3F1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Ribose-phosphate pyrophosphokinase 1</fullName>
            <ecNumber evidence="4">2.7.6.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Phosphoribosyl pyrophosphate synthase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">BGZ80_010110</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>D-ribose 5-phosphate + ATP = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15609"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.6.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Metabolic intermediate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route I): step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ribose-phosphate pyrophosphokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.1" evidence="4"/>
    <dbReference type="EMBL" id="JAAAID010000067">
        <property type="protein sequence ID" value="KAG0023205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3F1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002189">
        <property type="term" value="C:ribose phosphate diphosphokinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004749">
        <property type="term" value="F:ribose phosphate diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006015">
        <property type="term" value="P:5-phosphoribose 1-diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006164">
        <property type="term" value="P:purine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009156">
        <property type="term" value="P:ribonucleoside monophosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2020:FF:000017">
        <property type="entry name" value="Ribose-phosphate pyrophosphokinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2020:FF:000043">
        <property type="entry name" value="Ribose-phosphate pyrophosphokinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003889">
        <property type="entry name" value="FYrich_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000842">
        <property type="entry name" value="PRib_PP_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029099">
        <property type="entry name" value="Pribosyltran_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005946">
        <property type="entry name" value="Rib-P_diPkinase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01251">
        <property type="entry name" value="ribP_PPkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10210:SF57">
        <property type="entry name" value="RIBOSE-PHOSPHATE DIPHOSPHOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10210">
        <property type="entry name" value="RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05965">
        <property type="entry name" value="FYRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14572">
        <property type="entry name" value="Pribosyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13793">
        <property type="entry name" value="Pribosyltran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01400">
        <property type="entry name" value="Pribosyltran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51543">
        <property type="entry name" value="FYRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00114">
        <property type="entry name" value="PRPP_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0418">Kinase</keyword>
    <keyword evidence="13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ribose-phosphate pyrophosphokinase N-terminal" evidence="18">
        <location>
            <begin position="354"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="14"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="122"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="20"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="51"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="83"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="122"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00040334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00077829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF13793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAG0023205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="716" mass="79881" checksum="0D2EAF6A93BB6469" modified="2023-09-13" version="1">MTVIEHTIAALGVDGDMKDQSSAAVSSDGNSRVTRAKKALAVQQDNKDASESEADEDDDQESDRDSNGSQSEDEESDRRDSGAEAEEPEEVDYEKQRQQNILRNQQLMMELGLQPISIRREFPIPVRPSRDKSRDDEDYTEEREYPKVRAKKRMRIPKPAYQPVQTRASKRIRGEPAKEYKVDLEALENGLQLDLNGKDQNELRSIATTIWDIGKIYKGKENRLKYWSGKGSMFRHPYPIGFRAEKHVFRERYTMHIKEGPDGPIFVVESEGGKVFEGSSPTLPWTKVCLASYSKGTRISGPLFFGFSDPITQKMIEELEGYQDWETVSSEERAKVEAKAESASEALNPDLKTKVFGGSSHPEITKLITSRLGVEPSAVKLSQFKNKETSVEIGVSVRNEDVYIIQSGSPKINDSLMELLIMINACKGASAQRITAVIPYFPYSKQSKKKKHRGAIAAKLVANILAISGVDHIITMDLHASQMQGFFNIPVDNLYAEPTVGKWIQENVEDWENGVVVSKNAGGAKRVTSLADRLNIDFALIHMDRSRKGHAQGPDHSLSKPENIYNRLEEEDDDDDSMVDAETGHEIHRAEAADETSLMTLVGDVQDKVCFIVDDMIDGCHSFLEAADNLVGHGAKEVYIIATHGILSGNSLRQIEECANVHKIVVTNTYPLPAEKRALCSKLVILDISPTLAEAIRRTHNGESISYLFTQVPKSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3G8</accession>
    <name>A0A9P6N3G8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_011486</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000093">
        <property type="protein sequence ID" value="KAG0022674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3G8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17353">
        <property type="entry name" value="MFS_OFA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF317">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="95"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="122"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="149"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="182"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="206"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="308"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="340"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="372"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="396"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="433"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="471"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="4">
        <location>
            <begin position="293"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0022674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="519" mass="56647" checksum="AC17B440CEA75D5C" modified="2023-09-13" version="1">MSERSSNALFREIHRDYSNTEYRRSPDTIEKEKYLIFGTPFRRWAMFPTAFLFQVICGSLYAWSVFNDPIDGYIYGLVTNPLTGKSAPPAHNATITFYIAVGCFGITAAINGPWLERNGPKLAAIIGTTIFFLGNMIAAIGIYAKIMVLLYFGYGVLGGTGLGLCYISPVSALQKWFPDRRGLAAGFAVCGFGAGSIILAKIPQPLIAAVGLPLTFVVLGCCYFAIMFLCAVVFRVPLPSFLIDGMDIYRNKVSAKTVDLPDKTELSLDVECEKDLEAHANERAAQDYRDPGVNMVLSTAIFSSEYRIIYIVFFGNSTTGLVFLSRLANIVKGTFGKDETTAATIVAINGGFNLAGRLFFSTVSDRLGRKNSFIVMLLCQVIIPATLPVIMDNQVYWVFLLEIWVLTACYGGGFGCIPAFLCDMFGPSNIGTLHGIILTAWSLAGIGGGLLFTGIYTSLLNDGHTANWRRILGVACVGFVSLLFVGTNIQDRLLPRDKGEIARIRVFGRLVRMGTLASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3R4</accession>
    <name>A0A9P6N3R4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_009107</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000052">
        <property type="protein sequence ID" value="KAG0023548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3R4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="297"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="575"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="660"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="181"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="581"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="598"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="668"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="819"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0023548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="819" mass="90243" checksum="1658073B0982A3CF" modified="2023-09-13" version="1" fragment="single">MNQTKGPNHLNSNQTPLILTEQAQDIERWDDAFEFDSNQSFDQIFEQLHRHLPRSPLSDSSDQSDYFQPRSHLPLSAHHPQEPLSDRNKTKPMACRRASCSSYTHALPTPPTTTTATTLMSSKPTHGILSDSARRFGGSEVSIKRLGITSRAKSDALPPRLPSPASTTTRDRGEKLDTECSSEQRSSSISSNTSSPRAVTASVTAPSTIAISTASMLNKDKGKESDEDECPTPSTKTMTTITLDMMLSSNLPAYTGIITRINPIKRVEDWVDDLDDLEVPEQDLDFSQVCSNLAKSSSAPETLESVDSWETDSENSATRSDDNFIQELQPRVFSPLPGPHASSTVQSPLLTARRNQKLQGASPNGSLLREQSSLLQWQDSGSDADSDFGIALDNRSLSSSGSSSKDSMGDDEDLLDGLIFPEAMEDLKLVTNRPYRPETEPSIFGKESRFQEDQEDFWDGLDISGEDLINRKGRNKNLVIRAVPLGRERSGSRVQRQVVPLKDFVALPSRIPRLCRAPGDTFKPVTPAPCLSRKHSTQFELPLRNLKSKSSLPRLKRGSISRRESIRSSLVLSPADATVPSSDSGSAYSSSPHVSRAPTPTTSFYQGSKRNSLLFNKDKDDFPSFKSSSLALRSVSFTEPKVTEPKVTDPEDNVLSEKPAELKEQTLPPQPPITSKPPSPPPASGKSFPSFRTLVKKFARPGFTARGLIPVFESSASPKLTPNVAVVVPPVEPHLLPADPEFSRRLFVIRSPKHSTFGDGSELDRLDNLPLYGSLETSEDERLRSTQLKAQIRKQSTDRVADWLRKPSIANFKELNKPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N416</accession>
    <name>A0A9P6N416_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Chitin deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">CDA2_2</name>
        <name evidence="6" type="ORF">BGZ80_003724</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000020">
        <property type="protein sequence ID" value="KAG0024379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N416"/>
    <dbReference type="OrthoDB" id="407355at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004099">
        <property type="term" value="F:chitin deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009272">
        <property type="term" value="P:fungal-type cell wall biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050248">
        <property type="entry name" value="Polysacc_deacetylase_ArnD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10587:SF133">
        <property type="entry name" value="CHITIN DEACETYLASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10587">
        <property type="entry name" value="GLYCOSYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="363"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="NodB homology" evidence="5">
        <location>
            <begin position="106"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="324"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="324"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0024379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="387" mass="41686" checksum="BA7CA920F0CFC4AD" modified="2023-09-13" version="1">MSFARVILRPRFISIIAYTIGAICVQAASSGSSPSAITYPRIGAIPSINSPEVQAWLKEIDLSGSPLIGLNHGVPPDCPAKIDSSVCYWTCQGCAEDDVVACPNPNVWGLTFDDGPTEVTTSLLKVLHKENVKATFFLIGGNVVQFPEVVKAELEQGHHLASHTWSHHTLTTLTNEQIVAEMKWTEKAIEDATGYRVKYMRPPYGDVDNHVRFVLKKLGYIIVDWTGDAFDTDDWKIPMKQANVSSVTTHFKKSAATYNANKSLSKKGFISLEHDLSVETVRVAKELIPYGTSHGLIIQSIPNCLHDATPYAAMNGVVKGVNGSHSTTGSSGMNTGAQSQKGKNDMVTSTSVSTSAGASRQHFLGHALMLSPTILALGPIVVAILAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4A1</accession>
    <name>A0A9P6N4A1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_010403</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000072">
        <property type="protein sequence ID" value="KAG0023101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N4A1"/>
    <dbReference type="OrthoDB" id="2310150at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19075">
        <property type="entry name" value="AKR_AKR7A1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF4">
        <property type="entry name" value="NAD(P)-LINKED OXIDOREDUCTASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="16"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0023101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="355" mass="40021" checksum="E6C55F2FC88CBEB1" modified="2023-09-13" version="1">MTSNNNNNNNNNLPRVVLGTMTFGFETRHDLSLVRVCGAENAKPFLELFGSHGHVEIDTARVYGAGTTEQVLSQLPTAHFKIATKAWPFEDGSFNEENLAAQLRQSLKTLNTTKVDIFYLHAPEGATPLEVTAKAVNNLYKEELFERFGLSNFPSWQVALIHEICKQNGYVLPTVYQGMYNPISRSVVPELLPCLKHLNISFYGYHPLASGLLTGKYKFDKDVADGLRFDPKTGYGKNFRERYWNQLTFEGIEILEKAAAENQITLLEATLRWMRHHSGLEAKDGIIIGTTSLKNLEESLRDLDKGPLDESMVQAFDEAWEKVKPSSQYYAKHTTMKFPAPAIKRLMGQAEDQAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N6A2</accession>
    <name>A0A9P6N6A2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_001323</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000013">
        <property type="protein sequence ID" value="KAG0024566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N6A2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040139138" evidence="2">
        <location>
            <begin position="20"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="254"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="305"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0024566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="542" mass="60152" checksum="84D840E788A5FCC6" modified="2023-09-13" version="1">MKFTNSVLLLSLSLTSALALLSEASPAPFPNAHPDSSSPTPRQGPHPNIHTRKSRTDPSSDLTAASIASLDNTHPQRLRRQGNNDNINQRLSSSILTPSFLDVQSRQSSKIVTSGKSDITHQRRRQRPITARSPTQKKTRTLVKRASPAAKKPPLLLLPDSRSIWQTGSYQTVKWSLKYSKSLPKDTTVDIVLVDSKTNRKVSSLKRFVPFKKGSAQVWVPVNLPEGLSFVLVLELYHGRSQEQVISTILSSSSQSSSSYQNKNQASPGKVSDSMEENSYGDKSSPSTSTDILSTVVRRSDISISSGARKMARDTPYPGSPGSVNSVNGGVFGTSKAGAHHDINNNDYYTGDAKEQPLEFLPEEMREEYPNTVLPLVLEHTFGLHQKVYTMTPYTLEWKIPDRIRELLEYTRQVQSAASLWSKNNQKPPATPTSIFLAKVLVELVTEQTLESVVVMARDIPAETMFQYLSIQEHIPPAFYRLRVQMVVVQVNVDGKTLNIGQVPPPITNSKSMEGWEFPNGGQVIDRYEAVTRRFWVSQGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SRJ6</accession>
    <name>A0A9P6SRJ6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_008051</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004254">
        <property type="protein sequence ID" value="KAF9993717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SRJ6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1410.10:FF:000007">
        <property type="entry name" value="Ribosomal lysine N-methyltransferase 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1410.10">
        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050600">
        <property type="entry name" value="SETD3_SETD6_MTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271:SF34">
        <property type="entry name" value="N-LYSINE METHYLTRANSFERASE SETD6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271">
        <property type="entry name" value="UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="2">
        <location>
            <begin position="73"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9993717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="280" mass="32508" checksum="E080357A3C1D4C4A" modified="2023-09-13" version="1" fragment="single">MPKYGGFFCYYQKDEELFSIPRPLLLSPETSELPKKINLTSLQGWNPLMMCMIYEYCRGEASHWKPYFDILPEEFCTPMFWNSEELQELKGTGIIDKIGRDEAESIFKEKLWPLISANLDQFSVEDKDEASFLKIFHRMGSLIMAYAFHDTLPDKDEDEVMDEDGEDEEEEEEEKVNVSMVPMADMLNHRTGFNNARLFHEKDCLRMVAIKPIKAGQQIYNTYGDLCNADLLRKYGFVDVPNPHNIVEISGDVVVEKFRAGNEEGKEEIVEWLLEQDALE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SVE3</accession>
    <name>A0A9P6SVE3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_005123</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002544">
        <property type="protein sequence ID" value="KAG0006828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SVE3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="234"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="188"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="188"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0006828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="338" mass="37946" checksum="6FDF379FE4FDAD3D" modified="2023-09-13" version="1">MDLTSEIQQLLSSNASDEAFINPSSAAVLFPAFGELNDHPITQDAHNSGGADPEIGDLFGLEITQAHEFQYFNQEGELFSHGLLFGMPAPYSSTSALQQQLQQQQEWNYEDIHLNQSLFAPSTAFTWHEPLTSDFSVFRTQDSDDFPSPEGYALMPFADLNVTAMMNESSSFSQVGSQSLSPVAFSSTSPISSLNSSEPDEYESGINASKRKKRYRKKIDSDAKPKAPRLTFYCPEEGCNVTCSSEPSLARHVESHKWRGKYHPLRCEGCQSGLSNEYAVQRHITRSADTMPCRRMSVYSFMKSKTEVDITVRFNRDRPHGKKTVQVNLEEMKAMYLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SVG5</accession>
    <name>A0A9P6SVG5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phenylalanine ammonia-lyase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005232</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PAL/histidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002597">
        <property type="protein sequence ID" value="KAG0006530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SVG5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016841">
        <property type="term" value="F:ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="entry name" value="Fumarase/aspartase (N-terminal domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001106">
        <property type="entry name" value="Aromatic_Lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022313">
        <property type="entry name" value="Phe/His_NH3-lyase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10362">
        <property type="entry name" value="HISTIDINE AMMONIA-LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00221">
        <property type="entry name" value="Lyase_aromatic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="L-aspartase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00488">
        <property type="entry name" value="PAL_HISTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0006530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="175" mass="18675" checksum="3CA27A1C90C92B4D" modified="2023-09-13" version="1" fragment="single">MPPITSVCATTGMFEESENTDPVLLSGNNLSIDELILVARGGHSLAISTDPELRDRIDRAYKSIQQAVINKETIYGVTTGFGGMANILISGDEIDALQDNMLWFLKAGTGGRLPTVDVRAAMVLRANSHLRGTSGPRLELIERILEFVNAGVTPHVPDLGSIGASGDLVPLSYIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SW32</accession>
    <name>A0A9P6SW32_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004126</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002139">
        <property type="protein sequence ID" value="KAG0007873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SW32"/>
    <dbReference type="OrthoDB" id="2411349at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040450069" evidence="1">
        <location>
            <begin position="19"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0007873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="95" mass="10352" checksum="8B09E1ADD5BD65E2" modified="2023-09-13" version="1">MLKPTILAITLLVASVFAEDTRITYKLAKGQTVDEFCTAWSNECYKYVPKVQPGSEVGEYCEGGPKKGQVQAYCNAYAVTLYGSAVAKILHDKPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWS4</accession>
    <name>A0A9P6SWS4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ataxin-10 homolog</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Copper transport protein 86</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_003259</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">May play a role in the regulation of cytokinesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ataxin-10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001855">
        <property type="protein sequence ID" value="KAG0008599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SWS4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051374">
        <property type="entry name" value="Ataxin-10/CTR86_families"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019156">
        <property type="entry name" value="Ataxin-10_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13255">
        <property type="entry name" value="ATAXIN-10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13255:SF0">
        <property type="entry name" value="ATAXIN-10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09759">
        <property type="entry name" value="Atx10homo_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ataxin-10" evidence="8">
        <location>
            <begin position="485"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="252"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="300"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="260"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00044801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00044805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF09759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0008599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="588" mass="66137" checksum="569ADA779115BE55" modified="2023-09-13" version="1">MELGSHDDLWTSLALILNKVIKDGLDPEQVEQLMFLFRIIRNSAAGVSENQDRARDSNQLKLIQEIISQAAHTHYGNVTYIMMLRAGVQALSNLVTGNNVSKDQMWKSFLAEAPSPSCDQYLLSTLAAIEDETIVLSTVMLCYNCIFESRERSDLLFSTSAGKKLLTQLVNESHSSSGKEERKSFEMIFTFFDHLISRDYFPQLFEVLRNPGVESEEEYSIRYHGEGFHDKKTEQGKDDVDPLPKIRELKIEEIQDEEGDHSQKARMEGKKNEERQYLSAEHVVLLKIIDSRIYCHHDLQQKRHRERHSQIDARNSSSEDGPAISLATVRCLTEIFVRASVLTIEIFKTLEQPGIGQHGVEDLANMSSGLILLLGCFAHLSLYEDGFIAKEQILLEGDVESLETPGEPLPVPEWFKAQHMEMINGGLIESAIELLRQADKSLVRVTKPVAAMPNTATPAMAANTESTLVSNTSTEQGQQSFFFGVKRDIVRLVGNLAYRSRHVQDLIRQCNGLIVMLSQCNIDDANPYLREYAILAMKNILAGNIENQALIEELQPIEAVDHPALQEARVTAQLDAKTGRPVLTQKKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SX46</accession>
    <name>A0A9P6SX46_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_002448</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001604">
        <property type="protein sequence ID" value="KAG0009388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SX46"/>
    <dbReference type="OrthoDB" id="2413739at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0009388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="135" mass="14647" checksum="FFD060F22B2D2B8E" modified="2023-09-13" version="1">MALVSGNTSDLGNIKNRISFREDLNDTHHCDDDGFSSDNFSDDDDATSPPNDADTAEIASIERRALKYRQSLTMLNQLARMSIADGDEDATSDEASAPEGIRQPSKEHLLAAKKSIDDLTAWVNASALGDDDDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SX58</accession>
    <name>A0A9P6SX58_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ABC transmembrane type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_002592</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001644">
        <property type="protein sequence ID" value="KAG0009245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SX58"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056227">
        <property type="entry name" value="TMD0_ABC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF443">
        <property type="entry name" value="MULTIDRUG-RESISTANCE LIKE PROTEIN 1, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24357">
        <property type="entry name" value="TMD0_ABC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="27"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="65"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="93"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="261"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="310"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="281"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0009245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="409" mass="46026" checksum="CD1ED97241A4CD6F" modified="2023-09-13" version="1" fragment="single">MGIDAFCNDQEGWGPTSEMRADLTPCVENTILITLPSLIALLAITARTHSMWRYGKPHNLGRTNIIYWPSQFFILASVAALIARAALLHQDTYAPATMLSTICLILTWISAIPLNHLQHQQKIRSSNFIFALYFFTLVASAINIRTMSLLGQTYQNQFIAFVTFFGLNLTGFIVEAFPRGRTQAQKKSGAGRFQKANLASRISFNFLQPIISLGFRSPLTFKDIDGMMPERIKTQYSYEVLNNQWQKDVARAKAKGKKPNLFWTILSSNAWSWGPVMFHRIVASTLTYVLPTLMNNLLSFINSYSTPTPQPVSLGIILAFGMFFASLLNSFFMAQYFQASMNIGVETRTALIAMIYRKSLKLSSAAKQKSTAGEINNHMSVDAERWNDLSSFLPMFISIPYELAIALWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZ08</accession>
    <name>A0A9P6SZ08_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_011471</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000925">
        <property type="protein sequence ID" value="KAG0012850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZ08"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008023">
        <property type="term" value="C:transcription elongation factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000987">
        <property type="term" value="F:cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032968">
        <property type="term" value="P:positive regulation of transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042795">
        <property type="term" value="P:snRNA transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2670">
        <property type="entry name" value="E3 ubiquitin-protein ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042065">
        <property type="entry name" value="E3_ELL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031176">
        <property type="entry name" value="ELL/occludin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23288">
        <property type="entry name" value="OCCLUDIN AND RNA POLYMERASE II ELONGATION FACTOR ELL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23288:SF17">
        <property type="entry name" value="RNA POLYMERASE II ELONGATION FACTOR ELL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="294"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="351"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="368"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="383"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0012850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="573" mass="62171" checksum="635F9D003C05C272" modified="2023-09-13" version="1">MPLNHNDQFVVNAAQPSRRQIIEFKLSEEVLEEILNGNESIQLDLNQAKLLVGETPYDFSQMPGISNIEVYKLQSGSKQLDLVGDISAKCTIQRTHAKKGQKKATKHEPQRTVFRTNLRQRKGRKKGGSKLSGTAPVRRTLSPSPSPATAAVASAATTAAATAATAATAGTVVPLKTRVVQLLALHQRGVEEKELTKLLRVRIEDLQSILPIIANYSGGRYVLKPETYKEVKIYDWKNYSAKERDIVVNNASAAFDRLGLSSDAPERDILFPEKTKRASPPLVAEGYHVLGNMETTNSKWRSGGGGGGSESEGLDNGRMSSSGSSLLKPPTQKKTSAKKSPGTVASKTKKTSSSSKKAAAAAILDTVPNHSTRGAATPSSMKRTSETKKTGSKETGGVGNGYKIPKVGSGATIPRKPPSPGFTVPSITTQAEYEETSRKFMAKYKEMKDLKTRIDKKKELFDQLGAELERAMGTEREGELKRKIQDAFGEEIIDRKVLRRTGEPRNGISSKRAAVAIAERDKSLNLSVRSMAERYKTLHKEVDMMKRALWEAGTAQAERVGQHISGTSGGGNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZ31</accession>
    <name>A0A9P6SZ31_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_011362</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000903">
        <property type="protein sequence ID" value="KAG0013013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZ31"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="64"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="208"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="271"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0013013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="457" mass="45616" checksum="CDADF301C3050D9D" modified="2023-09-13" version="1">MPRGPAQESNAGPPMQNAAPPPVQGRHPKTGGIKSIFDYAKGMQWDRGNQPAAGSPVANNPQDPSYYANANGAPAASGSAYNASYGQAAAPASTPAGASAPYGQPGTGTPQGYGQQPHAQQYDPYATQPPIANNAAAPYQQDWYANNPANVQPGAATAAPVRGPNGREWQAPVDQNTPYKRPPNAGRGGRGGGRGGFSGGSGRGGHTTSGFNNSNNNAAHNNSSANTNNTSSVNSIPLNQNNPAAVAAGYGTNGYNARQPPLPTQPPPPSVQQQHQQQQQQQAYSQAYTQAYGYPAAASAATSYQPAAGAYPVQPQAAAYQTPAAAYQGAAATYPAAGAAAANGYQAAAATGYPAAAAATGYQAGAAGYPAAAAGYQASAASYQNTATAAAYQAAAGYPAAAAGYQATATYPAAAGAYPAAAPGYQSAASAYQTPVAGYQAPVAGYQASATAYPPYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZQ1</accession>
    <name>A0A9P6SZQ1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_011306</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000896">
        <property type="protein sequence ID" value="KAG0013063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZQ1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032981">
        <property type="term" value="P:mitochondrial respiratory chain complex I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050602">
        <property type="entry name" value="Malonyl-ACP_OMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13090">
        <property type="entry name" value="ARGININE-HYDROXYLASE NDUFAF5, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13090:SF1">
        <property type="entry name" value="ARGININE-HYDROXYLASE NDUFAF5, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0013063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="275" mass="30775" checksum="7CF2E0C12F7E5F48" modified="2023-09-13" version="1">MHSRSIPLLRATSQILTRSLRNTPRFHLYSTASSAGAKTVPATFQVFDREGKRLQKERAASNVELSRQVDYVKDEVAFRVVDRLLDIKREFNEVVELGSGCGHIAKHVDSDMMKKLIMCDMSEMMLKRDKDVEYEAWSVLTSLQLAELDREGGISPRVSPMADSRDLGSLLSRAGFTLTTVDVDEVTVNYPSAIELMEDLRAMGESNAVIGRRGLLKRDTMIAASAIYKEMYGNPDGTIPATFQILYMANWVEAFTDTKQAIGERFCKTFSQGPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZR7</accession>
    <name>A0A9P6SZR7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">STAS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_010437</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000726">
        <property type="protein sequence ID" value="KAG0014437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZR7"/>
    <dbReference type="OrthoDB" id="427213at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07042">
        <property type="entry name" value="STAS_SulP_like_sulfate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="entry name" value="STAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001902">
        <property type="entry name" value="SLC26A/SulP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00815">
        <property type="entry name" value="sulP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11814">
        <property type="entry name" value="SULFATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SpoIIaa-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="200"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="243"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="283"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="375"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="410"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="434"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="473"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="7">
        <location>
            <begin position="537"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0014437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="670" mass="73828" checksum="E4A384887DE9CBBD" modified="2023-09-13" version="1">MTRATQGNSSHRYSPVHVDSSDSDDSDEQTPFVRRGRAYGQPQEDEEILTLPPTADLWTTFRTRMKYYVPVTRWLPHYSMDGFGHDFIAGLTVACLIIPQSLSYATALAHLDPIHGLYASFVPGVLYAIFGTSRQLSVGPEALVSMLVGTAIAQQQHSSGNTDPKTALAISCFITLFVGLFTFFLGFVRLGFLDSVLSRALLRGFITAVAVVVIIEQSISLFGLKALADEFGIGEESSTVEKLLFIIEHFGSIHILTTVVSFSSIIFLLSFGSLKKRLTKLPFLQFVPEILLCVVLYTILTALFRWDKDGLAILGATKADGFQLPSIPAVPEGVSIRSLFGTSVLISIIGFVESIVISKQYATKHNYSVSPNRELVAMGVANIFGGLFQAIPAFGSLSRSKINDKAGARTQLAGLITALFVLLSIFFLLPYFFYLPKAVLAGIICVAALSLLSEAPHDIKFMWQIQAWSDLGLLLLTFIATISVSIEAGTLIAIALSFLLVIKTSTYPRITIMGRMPGTRGKFRPIKDYPGIAEHIDGVLIIKVEEPLYFANTGQLKDRLHRLEVFGDMSVHPSEEARLNPVSHVIFDVENMPSLDASAAQILLEIVEAYHARDIRVYFVKLHENSRELFIKSDLLERAGGEAHLFRRTADAMEFIERESLCLNMGEDNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0D8</accession>
    <name>A0A9P6T0D8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_009770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000613">
        <property type="protein sequence ID" value="KAG0015594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0D8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="172"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0015594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="217" mass="24139" checksum="57ED234CC8F464CC" modified="2023-09-13" version="1">MGFYLVGIIYATPASFSIHHNSTLSTSKKRRSYDFNNVLGGSEKQLSVMEPKRVYLPKPMALNFTLLGLIILPLVSSQILASFAGAAYDRGEMSLYSSLISSMYAIWASVAFVIFVLYIFFGKQLLTIISSNMASINDSVGRISSRIGANSDYEENELQLNTLKATYQRMRAVIVLCGSLSLFMGLMMLFFAIFRKEILSNVSASQAFSLFWIHGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0K9</accession>
    <name>A0A9P6T0K9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">protein-serine/threonine phosphatase</fullName>
            <ecNumber evidence="4">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">PTC2_2</name>
        <name evidence="8" type="ORF">BGZ80_009319</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PP2C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="4"/>
    <dbReference type="EMBL" id="JAAAID010000546">
        <property type="protein sequence ID" value="KAG0016285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0K9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832:SF565">
        <property type="entry name" value="AT28366P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="7">
        <location>
            <begin position="23"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="285"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="331"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0016285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="345" mass="37208" checksum="A8E6C24EB2FFE9CC" modified="2023-09-13" version="1">MGQTLSAPITEKHSSADHDKRFAYGASAMQGWRITMEGSNVAKYSGEGLHKRIVGDKAFAKKDYMAAIKNGFLEMDRALRFDPEYGGDSSGCTAITATFTSDNVLYVGNAGDSRAVLGSDGTAIALSNDHKPVNKEESRRIVAAGGFVEYGRVNGSLALSRALGDFEFKMNATLGPDDQIVTANPVIVEHKLQEEDEFLVLACDGIWDCMSSQEVVTFVRKGISENIPLDTLCEMTMDHCLASDSGLTGVGCDNMTMVIVAILNGKTLEEWYEHITKRVAVRLGPADSKPRANGDEDPEALDEKSSESEGSNENSKIHENQEEEIPNEPSALKDGDEKGAAETAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0P6</accession>
    <name>A0A9P6T0P6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_009366</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000554">
        <property type="protein sequence ID" value="KAG0016205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0P6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="249"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="306"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="344"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="377"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="388"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="398"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0016205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="437" mass="47716" checksum="96C5EAD19C446A22" modified="2023-09-13" version="1">MPSLEFSPKAQPGPTHRRNGSRDFATEAHQQPHHIQPNGPGPGMYPRTIPTPPKTPDTKMSLKFASNMSRSISLGSSDRQGMNAPGTGAPLHQQYLAQNGTSRPNLPGIASIHKLQHPLVNNSSNSSNNSHYPYVASTMGGMVSPSSSTTTSPPIRMAQSSSSMAISVGRPQSPYSQKHPESFSPQPQHHQSLNYALPRPNATRHESLGSHAGRFIRGHQHHRSLDIDPFSALAELANLAEKHREMPEDAGGFEGGELMSRSGSSSSRPDLADVEDAVVKTMIERPPPPPGPLVMGRRFSTLGHVKEEEHGDDAEDTQSHHHSYHIDARNNSSSPIGHGKSYSGHDLSSSRDLLSSGYRSKRFSMDFSTTSEPASEHDDDEDMPMDEENIHNQDRRVSPPSSISRPSASYMAMRRGSVRELMAIDNLCLSSEEVERC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1E4</accession>
    <name>A0A9P6T1E4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF3419 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_007771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000403">
        <property type="protein sequence ID" value="KAG0017926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1E4"/>
    <dbReference type="OrthoDB" id="10253390at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021829">
        <property type="entry name" value="DUF3419"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47473">
        <property type="entry name" value="BTA1P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47473:SF1">
        <property type="entry name" value="METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11899">
        <property type="entry name" value="DUF3419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0017926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="414" mass="47918" checksum="88DF2F3CDF5D9BDC" modified="2023-09-13" version="1">MSLTVATPAELPLHIRALSSIVQLYHKSLGRKTIQSSSDTTIEASVDFSKIRYSQVWEDTRLLRQGLVLKPGSRVLSIASAGDNAFALLLDDPREVAAIDFSPAQLALCALKIAAYKTLDYVEFTQLLGFELDGHDIGAEARVALYQDKVRQALTNDEYRSYWDENLDLIHNKIIHIGRLEKFFGMYRKYILPLAHYKSTTRTLLDSQDQAKQIKFFDSIWNNWVWRTGVRTFFGQMSLGHLGRDPKFFEHVRLDVGAFLLGKINNGVRNIPIWDNFYAEYVFTGQQTGKNSLPDYLIKENYDVIRSRIDRVKLVRADVLKYLQSEESGQFDGYNLSDIFEWMDEDLFKTFLTAIHSKGTKDARICYWNLFVPRERPEELRDLIRSEVELSDAATAKDRTYFYRRFVIETILKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2K5</accession>
    <name>A0A9P6T2K5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Tubulin beta chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">TUBB4A</name>
        <name evidence="16" type="ORF">BGZ80_004471</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4 12">Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the tubulin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000228">
        <property type="protein sequence ID" value="KAG0020270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2K5"/>
    <dbReference type="OrthoDB" id="1662883at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005200">
        <property type="term" value="F:structural constituent of cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000070">
        <property type="term" value="P:mitotic sister chromatid segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097435">
        <property type="term" value="P:supramolecular fiber organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02187">
        <property type="entry name" value="beta_tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.600:FF:000002">
        <property type="entry name" value="Tubulin beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.20:FF:000002">
        <property type="entry name" value="Tubulin beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1440:FF:000003">
        <property type="entry name" value="Tubulin beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.600">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="entry name" value="Tubulin/FtsZ, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="entry name" value="Tubulin/FtsZ, GTPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013838">
        <property type="entry name" value="Beta-tubulin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002453">
        <property type="entry name" value="Beta_tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000217">
        <property type="entry name" value="Tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023123">
        <property type="entry name" value="Tubulin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017975">
        <property type="entry name" value="Tubulin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11588">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03953">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01163">
        <property type="entry name" value="BETATUBULIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01161">
        <property type="entry name" value="TUBULIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="Tubulin C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="Tubulin nucleotide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00227">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00228">
        <property type="entry name" value="TUBULIN_B_AUTOREG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10 12" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 12" id="KW-0493">Microtubule</keyword>
    <keyword evidence="8 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin/FtsZ GTPase" evidence="14">
        <location>
            <begin position="47"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin/FtsZ 2-layer sandwich" evidence="15">
        <location>
            <begin position="246"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="427"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="429"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0020270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="448" mass="50114" checksum="386C8C965F93BD26" modified="2023-09-13" version="1">MREIVHLQTGQCGNQIGGKFWEVISDEHGIDNTGVYGGDSDLQLERINVYYNEASGGKYVPRAVLVDLEPGTIDAVRTGEFGQLFRPDNYIFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQITHSLGGGTGAGMGTLLISKIREEYPDRMMCTFSVMPSPKVSDTVVEPYNATLSVHQLVENSDETFCIDNEALYDICFRTLKLTAPSYGDLNHLVSVVMSGITTSLRFPGQLNADLRKLAVNLVPFPRLHFFMIGFAPLTANNSQSFRALTVPELTQQMFDAKNMMAASDPRHGRYLTVAAMFRGRISTKEVDEQMLNVQSKNSAYFVEWIPNNVKTAVCDIPPRGLKMSVTFIGNTTAIQELFKRISEQFTAMFRRKAYLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATVEEDQGEEEYADEGEEMDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2Y5</accession>
    <name>A0A9P6T2Y5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tim44-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_002736</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000169">
        <property type="protein sequence ID" value="KAG0021267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2Y5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0021267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="361" mass="41709" checksum="3A5D9544DF8B66AB" modified="2023-09-13" version="1">MSFLASRIRPLSFVARAIPRNKPVWACGIHFSSVRYNPRYNDIRPERPTLLASSGEDKVKAEGVDSTEEPGEPSEAEIQALAYDFPWLYDGSSHLSRIPHYPYAKAPKIWALLGIIPQSIQYLICKSACERMLRNNTSPEYFPDQFLQGAGLAMHQMIPLISTNIDREPLTHMMTQELYDRFESELEKQEAVKSEVNIKLAAIHDGMVKDVWVLLGPKLKSGSTRGFIRWRWQSLTVVLRAATDDMSSRDQVTQMMMEGVQFKVDVEFDASIDYTIKSNVLNQDVVSDFTRRPLLVRFETPFFEPADKMVASRSMSRPHEAPIDWNWRVSDIDYLLEQDFIVRRQKEDVKDEEHARREMEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T307</accession>
    <name>A0A9P6T307_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004647</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000235">
        <property type="protein sequence ID" value="KAG0020174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T307"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="498"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="504"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0020174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="698" mass="78264" checksum="20CA483F5E1804C5" modified="2023-09-13" version="1">MAPLLNAKAWLKRRRAKCRFANKNNNNNNNKESYTPGIGYPPMRNSSQPTLIPYIPPSASSTSSEHDGPESSLETVIQDITGAATTTCLGVSYQSTALHSAAAVANGTDAVVPGPSNDYHDDYCRRYQEINQSAATLVSTFHDHRRISLQPGKPFAIAITAQSQNNHCQHPLRQKNGSHNSLPAQLLSNDILSELKNCPQVGQNRHQRNSSTPQPQKPLSTLKSSRFAASTDTLNMAETKAQEYARTVKALWQMVEDEDLAYRLADCSPVEREWLIFNHKNANFPMKPASEVGVILLENGRSSLENCRSNRAAGSGASAARGAALARIDEAVQYEPSEYGGRSKGGYRPYENSDGYSQPIIMSLPNSPVAGPIDSDPKKSRRSTLLSPMVLHSARELQKRDHITVQQRVDMEEDWRMQARLLRSQSECEDRARGVRRVHDQLIQRQRRQRGLGGAIIPEYEPTHNDFNKWYDLKEEIDDDAVPDLMNDDVRGYDLKEEFEDEEEKKQRELEEKEEMKKKELEELEQELTTLGLDRFDGMISFVEPDARVPQHQQQQQQQAQELHQQLQYQYQQLQLQLEMQRQKTIRSKKNRARAKKAAVAFADTAASSSASSDTPVMGTVSSPAILPPPPIPGNKPSSKLIVLPTSTPLPAPPANKMVLHEPRPLRPRNGRNLFSNECCDSMIIKDMPMVSAPTRIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3E0</accession>
    <name>A0A9P6T3E0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_001963</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000147">
        <property type="protein sequence ID" value="KAG0021655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3E0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032541">
        <property type="term" value="C:cortical endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097038">
        <property type="term" value="C:perinuclear endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048309">
        <property type="term" value="P:endoplasmic reticulum inheritance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000921">
        <property type="term" value="P:septin ring assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013635">
        <property type="entry name" value="Ice2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31726">
        <property type="entry name" value="PROTEIN ICE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31726:SF2">
        <property type="entry name" value="PROTEIN ICE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08426">
        <property type="entry name" value="ICE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0021655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="194" mass="21539" checksum="9956C46E6FA14D50" modified="2023-09-13" version="1">MVMSMYIAARNEAIENGPSKARIMPLHSAVEFGPLSIPYLQSLSLQDVEKITIQALVHLSQLIQVVIRALSPNLIISLVYRMGVLMTVSHIAPSLNIGQDGHSYPSSRTSRKSLQDDSVDDDDDESSGGVMSLLASLAKPVLLMTYTRILLQYFGYLRPSLAIWGWLNSFLCLALFAAELVLARDDAWEHYRSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3E5</accession>
    <name>A0A9P6T3E5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA polymerase epsilon subunit D</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">DNA polymerase II subunit D</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_001238</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000128">
        <property type="protein sequence ID" value="KAG0022009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3E5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008623">
        <property type="term" value="C:CHRAC"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008622">
        <property type="term" value="C:epsilon DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031490">
        <property type="term" value="F:chromatin DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031507">
        <property type="term" value="P:heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006272">
        <property type="term" value="P:leading strand elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22928">
        <property type="entry name" value="HFD_POLE3_DPB4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003958">
        <property type="entry name" value="CBFA_NFYB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051377">
        <property type="entry name" value="DNA_Pol-Epsilon_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46172">
        <property type="entry name" value="DNA POLYMERASE EPSILON SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46172:SF1">
        <property type="entry name" value="DNA POLYMERASE EPSILON SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00808">
        <property type="entry name" value="CBFD_NFYB_HMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transcription factor CBF/NF-Y/archaeal histone" evidence="6">
        <location>
            <begin position="9"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="96"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="98"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="155"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="200"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="214"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00039775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00042096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0022009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="223" mass="24080" checksum="2F19650F5282F62C" modified="2023-09-13" version="1">MSTSIEDNELPKAILTRIMKHVLPENTNIQANAKLAMTKSTTLFINYLASAANDVAASAGHKIVSGAHVLKAIESLDLEEMLPRLNEEFQAFQAIQRSRKEGAAKSSKDKDDSPSSAASKKRKPTADGSNLAAKSRKSSTTANPGDGRDASATDAMDDEEAGEEENEDADEKEDQDDDENEDEDEEDPDAADNGAASLNMDEKEKDDDEKAPNLDEEDDSDGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3Y2</accession>
    <name>A0A9P6T3Y2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_010397</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000072">
        <property type="protein sequence ID" value="KAG0023095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3Y2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="298"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="387"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="136"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="298"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="316"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="347"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="388"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="426"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0023095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="511" mass="57206" checksum="0F70139C2665E67D" modified="2023-09-13" version="1">MKLFKLDLGIKDRYRRGLAQGARVTRSPQTESTASFNELSHEYDPHHQATSPSSPSVLFSVDVSSLKMENEPMEQWSQFGSSLEASCSTEVQSGENNQIVEGYAVTMAHTLARSDGRHHGQEYDNGDEYENEHSNDGYLSSASSSSVSSGGSLSSSSSLSPSSSSYSSDESDTSDDDDYSDEDEDMQGGADDADNQDNSLENHSPGFGYNQKLHFDYYSGGRHDVNGHEGMLPPAPIPAIEPMSNRDALEQEARQRRLERHIDKRRQSLNGGQPAPELIREEAEKEIAKHKGYIELRNTKLYRADRNRDNGGEEEKQGDEEAKEADNDNNDDADDEDDVDTIYSPESMEECSSEELDVSHDIYHEKIKTLRLPPQGYMFDSIGVEGQDSVSSTESDASTIHHQKQKQQRGGGGQFLTFIRWKTKRSQSQQQKQRQQKQQQQQQQQQQQQSSLLTTIVVRDSTMSLKTPPPIVAPTPIRAFSSGRAMITSYWQRFRESSPTTSSQIHPSRNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T428</accession>
    <name>A0A9P6T428_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cyclin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BGZ80_009461</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cyclin family. Cyclin C subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000057">
        <property type="protein sequence ID" value="KAG0023422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T428"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20513">
        <property type="entry name" value="CYCLIN_CCNC_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000076">
        <property type="entry name" value="RNA polymerase II holoenzyme cyclin-like subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043198">
        <property type="entry name" value="Cyclin/Ssn8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10026">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028758">
        <property type="entry name" value="Cyclin, C/H/G types"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0010">Activator</keyword>
    <keyword evidence="5 9" id="KW-0195">Cyclin</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0678">Repressor</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Cyclin-like" evidence="11">
        <location>
            <begin position="46"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="237"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="246"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0023422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="266" mass="31234" checksum="7FBD2B78E6F68C3C" modified="2023-09-13" version="1">MAANFWTSSHATHWILDRRRLEEAMKEDLEYVDIATLTKIKMWYYNIIGKIGKRLQFRQQVVATAIVYFKRFYTKNSMRSTDPSLVAATCIYLACKIEECPQHIKHIITEMKNALANHGGFDYDTSKVAEFEFYLLEELEFYLIVYHPYRDLTIIAKNLKLEESNLQTACMATKKGVHHNAPQIEGHGINNRNMVQWFADLNVEIEEIIEITQEILSLYSIWKDYSEESIPAMIQSLKRPSRPTTPQQLQQQLLPQQQQQQQQQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T431</accession>
    <name>A0A9P6T431_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Arrestin C-terminal-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_000739</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000116">
        <property type="protein sequence ID" value="KAG0022226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="298939at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011022">
        <property type="entry name" value="Arrestin_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02752">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01017">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin C-terminal-like" evidence="2">
        <location>
            <begin position="636"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="231"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="332"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="813"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="926"/>
            <end position="1071"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1122"/>
            <end position="1218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1254"/>
            <end position="1329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1438"/>
            <end position="1557"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1824"/>
            <end position="1861"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="263"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="351"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="816"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="835"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="929"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="960"/>
            <end position="981"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="999"/>
            <end position="1009"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1016"/>
            <end position="1031"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1156"/>
            <end position="1169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1184"/>
            <end position="1218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1291"/>
            <end position="1300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1301"/>
            <end position="1324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1503"/>
            <end position="1514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1516"/>
            <end position="1529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1534"/>
            <end position="1557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1830"/>
            <end position="1860"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0022226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1884" mass="207462" checksum="6B53915E0CEFB765" modified="2023-09-13" version="1">MNGKDPSTLKQVGVSHTYPPSAEGHPVTSLASIQLSTTLSYSPSSPARLHSLQQQQQPQHQYQYQHQTRHDHQQYQYQTLQQPLQHSQAHIQPQLQTQQSALIQVQQPMKQKDDTYIPSKHQRLPTSSSSMAPAVIPAYPAYTNQGVAITRNSSIGQLPVVIPGAQATPNVMRSNAMYVSHPESSGSLQQSHPRPQYSRYLEHSYEEQQQRQYEQYEQQSRYYREAATMHANMQEKQHSEKARRYRRSTYSGSYNDTTPSWPQQQQQAHQLQAQRSLNLGSLPSNRFLVARDQLPTAPSPPVFSTTQPEPTYSKYIAAQPVPNFDDSSFNVTNTTGSIQTSGAGASRRSSESCVAQPSRRSGHSPYSMSSPIITERIVKPLAENQDPIAQLPLVGDSNRDHTVASLVRSNSESNRQSSGGPTMSKSTLKAFQNRAYSRQVTLSSIPPNEGVPPMPGKMTSKTGKVHIQLTFDKPFFNAGGELSGRLEIQCSSSSSIMFADIIIELLGYEALTKDHPSLKIFHKTVLRLQDARHPSQAVQENIDPDSAGYWAARKGRTIFPFRLNIQDTLPSSYDSKLGQVRYVTSAIARMKTNQQKEIVNHSREVFIYESWTTDDVIKARKKSAKADTSKRLFMGGEGSLEMYAELTRTMVSSGGIVYVNVGVKNLTKRKVMGIKLTLCRHVTVPNKDLSANTQVSVPANRDQDNVKNYCEIIYKGEDYAFDNDDPRMVVLPIYIPSGVYSLRNASYLHVQFFVQVSLMTSMNKALTVELPIYITHASSWSDPPPRIPRDFAFPTHEHDPVKKNITGVFSKKKVAPLQSRGSSSSLRKSPGICDSGSNTRDPYSAPSSQINTPTFLQGNARDGACTHPITRRSSPKDPDSPTSVLDFSQVKNLFVVNPDAASIRGTSDTASLMPLPTNLGVCSAPSPRVLQTGSTVPITTSLPSSMFTPLKPSDQPAPKPLKETEPTSHNLDNERDSDVGHPHGPSQVSSVKKEQEKPRPRKLGRKRTPAKLSIVIPNQSPNNFSLKQVSPISPRKRPTNPRSEESTNMESPEDISPGESKSPGGATLLSCNSSGSSLGSFKQMLDSISRKSSVGSTRVMAVSPGPMPTNCKSLKMTKCFPEASPPALSPRTVDVLESTPFGGSSHMHTEQTPTERQPDHLRVIPDLKLHGGTPMAEEKGSEGYSDSSGNGSRTPTSSSSVNRIATDQSSPITPNSSIKPWELQRNFSSSSISSSLLNSYEGIQTAKGIRDEYYLGKNGQNRRRSSDSFETRIAPPQTGDPNMVDSGMYNIHERESDKSDTNSPALLSGEDNQPQQQKACSEMSQRVAPVQGMSDNIQSRDADPLQVGSTQPSWDSRQYEVVISENDYTNRNQGCLSASQPENNQQLSPHTQATATQAILIHGGTPIPPSQDPEGRQACDDQLLQNQNAAPHQFLQPQLTSPLSNSDYERVTFPQPYTPGVQKNPEAQGVHPSFPTTSLIGRPLSHIRSPMEGTKAHLHPESSVVSQIASSTQREYLAEQDQRRAERSPTEIFTDPSTPISDSDIDPSRTYRSSTTTTISEPIVPTFFINSSETEQLVVTPGNRSENRHVSDGTTLIEQSCNPTVSVTANKQLYSGNQSCPSQLGPQHSTPQHWLPANTSAHEASVVGRDIRDKRCDKQRYAQVAETSQSPIGVYEEEISFIVPKMQLLSSQHMLPQETNLYDPRSYSSQVRNAENGQAPYQPCMQYTPKSRPPEGIQPNGQCTDHPSTAFNFHDTSYHDLKSQMSIASAYGAHPATAAPPIPERRWIHQSAPPVRPIVSYTEPLLNHVETSAPVISQANPCSNVPFLGTQPQNTQLQDTQPQVTQSQGTQSQDAQSSETGEIRNCTRFAASDALPFCVHHNQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T470</accession>
    <name>A0A9P6T470_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_008466</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000046">
        <property type="protein sequence ID" value="KAG0023695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T470"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0023695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="174" mass="17776" checksum="D7D81BBE395599B4" modified="2023-09-13" version="1">MAPEGDNSEEDEVGEREELAPALNKVLSEVGEDDELTRLRLPLEASAISMFPDAPSSTLISCPEALALLTSTPGALVAPGSFSMPSAACSSVLFDQSVLLSPVASPAPVCAFAAAAVATATATAAAAAADVDPEIFRGGRIVGPTNVHCTALRSQFLQGTPLSTSHLIFLNVIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T4G9</accession>
    <name>A0A9P6T4G9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="20">DNA polymerase</fullName>
            <ecNumber evidence="20">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="26" type="primary">REV3</name>
        <name evidence="26" type="ORF">BGZ80_005018</name>
    </gene>
    <organism evidence="26 27">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="26" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="26">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="18 20">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="19">Forms DNA polymerase zeta with REV7.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 20">Belongs to the DNA polymerase type-B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="26">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="20"/>
    <dbReference type="EMBL" id="JAAAID010000025">
        <property type="protein sequence ID" value="KAG0024236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016035">
        <property type="term" value="C:zeta DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042276">
        <property type="term" value="P:error-prone translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05778">
        <property type="entry name" value="DNA_polB_zeta_exo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05534">
        <property type="entry name" value="POLBc_zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.132.60:FF:000007">
        <property type="entry name" value="DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.690:FF:000002">
        <property type="entry name" value="DNA polymerase zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000024">
        <property type="entry name" value="DNA polymerase zeta catalytic subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.60">
        <property type="entry name" value="DNA polymerase family B, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.342.10">
        <property type="entry name" value="DNA Polymerase, chain B, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.690">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1600.10">
        <property type="entry name" value="Palm domain of DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006172">
        <property type="entry name" value="DNA-dir_DNA_pol_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017964">
        <property type="entry name" value="DNA-dir_DNA_pol_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006133">
        <property type="entry name" value="DNA-dir_DNA_pol_B_exonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006134">
        <property type="entry name" value="DNA-dir_DNA_pol_B_multi_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042087">
        <property type="entry name" value="DNA_pol_B_thumb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023211">
        <property type="entry name" value="DNA_pol_palm_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056435">
        <property type="entry name" value="DPOD/Z_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030559">
        <property type="entry name" value="PolZ_Rev3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056447">
        <property type="entry name" value="REV3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45812">
        <property type="entry name" value="DNA POLYMERASE ZETA CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45812:SF1">
        <property type="entry name" value="DNA POLYMERASE ZETA CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00136">
        <property type="entry name" value="DNA_pol_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03104">
        <property type="entry name" value="DNA_pol_B_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24055">
        <property type="entry name" value="POL3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24065">
        <property type="entry name" value="REV3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00106">
        <property type="entry name" value="DNAPOLB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00486">
        <property type="entry name" value="POLBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00116">
        <property type="entry name" value="DNA_POLYMERASE_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9" id="KW-0227">DNA damage</keyword>
    <keyword evidence="16" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7 20" id="KW-0235">DNA replication</keyword>
    <keyword evidence="15 20" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="12 20" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="13" id="KW-0408">Iron</keyword>
    <keyword evidence="14" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 20" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="17" id="KW-0539">Nucleus</keyword>
    <keyword evidence="27" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 20" id="KW-0808">Transferase</keyword>
    <keyword evidence="11" id="KW-0862">Zinc</keyword>
    <keyword evidence="10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DNA polymerase zeta catalytic subunit N-terminal" evidence="25">
        <location>
            <begin position="58"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="DNA polymerase delta/zeta catalytic subunit N-terminal" evidence="24">
        <location>
            <begin position="114"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed DNA polymerase family B exonuclease" evidence="23">
        <location>
            <begin position="1049"/>
            <end position="1215"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed DNA polymerase family B multifunctional" evidence="22">
        <location>
            <begin position="1318"/>
            <end position="1761"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="28"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="475"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="604"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="749"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="847"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="1023"/>
            <end position="1050"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="21">
        <location>
            <begin position="28"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="21">
        <location>
            <begin position="537"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="21">
        <location>
            <begin position="654"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="21">
        <location>
            <begin position="771"/>
            <end position="788"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00049244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00066055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="RuleBase" id="RU000442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF00136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="Pfam" id="PF03104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="Pfam" id="PF24055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="Pfam" id="PF24065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="EMBL" id="KAG0024236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1906" mass="214234" checksum="80E06518E5FAB1BA" modified="2023-09-13" version="1">MNTSNVLSSGSNDNTSWISNVTHSEDLKHNHQIQEPKVTEPPEADSNPTGIVARPVRFKIRIADLDYYMVEPGPLDLDTCQFLPPHCPILKVPVVRVYGSNEAGQKTCLHIHRAYPYFYVAYDGPLEQQQLQAYVQQLGMSLNHAACITFNSPQDLRKSQYVAAITPVKGIPFYGYHVGYSCFLKIYLFNPDFESRIFFVDFNLYGMGWLELEEALLRKEIPAPANGDHPKRLTKATVPDTRIWSLENDPGRMSHCEIEMDSTVDRIVNRDNAPERNTHTSLKECFKPPSLTVQVPSMAGLWEDDARRRKANNLPTQELPKTQIRDPVSIPWLNHDQNKLMVANLVREIISQSQIMTPTQGDFDSFKVGLDPLLESFTTAYESVDYLCPRESSDPNESFDQGLHEASFVFDEADSSILVDESIASQAVGFDMSDINSRKEIFKGLAGLGGLEEQDEEDDFPFPDIEEFQEEDFMDDPDLWDDMNSSDSETQGGSAFGRQDDVANHRIPQFDGGDDSENGQQEEGSGSGETSDEWKKVTQRTRIKRARSFSSSSLVSKEKVVKSKRYCEIVTSSSTSKLVALPTPSPQLPRVPVVAKVTDIKEYNKQQHQSSIKGADLPTPPFKSYETQDTESPRKKTRRMVRFVEIPKHPKKRLNSDGPRDPLRNSDTAEVIHSTSVLASHVSDDPILDGECDVEVGTQLQDQDVKLHEVGGSDQGVVSRISSASVLESQYPEPASPERRYFLSAMDEMWSSPSPPSDKSSFLHSPPRPTSPNSDSAQAITIPSSQSPAEKPIGSESFTDTSPVGLRYLDIDRPLLHSRRHSSVVDRTFMIDPLDMLDDDDLDAIHPRDKQDSHMLGEDSKHETRQSEISDHILAEDSIIIEPFCSESSPPRSLGTSLENASILPTSTPLVFKFSPAPPTTNELYSSLPRLGLPNVVHQKPFFSNDSDVPSKAKVFGDKEFRIYSNSIKNMPVFKAASDLGKCVSAGKGFRFWEPNQAPPSQVEIQSWLKEEKERVRKAMRSAAEASTQKRREQISQIEGPTPKNPFGYKNTPTKVAASIAVEKDFLDVLSLELHCHTRESFLPDPKFDPILAIFYCWQTEREGLISNGWVPGYRVGIFTHAEAGMMEKLAVGRVGYDIHMSENEGAMMNAFIEHVRELDPDILAGYEVHNLSWGYLMDRYQVLFGLDMSKLLSRVKPQKAPVLSKSAMEARDSYNSKHHSGLTFTGRHLFNVWRLIRGEVALTNYGFCNVVFHVLQQRVPHFSYETLTTWWTSGLALHQSRVIRNYLHRVQYNLQLIESQELISRTSEFARVFGVDFFSVISRGSQYKVESMMVRLAKPENYIMISPSRAQVAGQRALEVIPMVMEPESGFYEDPVVVLDFQSLYPSVMMAYNICYSTCLGKLGGGTKLGVTDYNIPDGFLPLVEDHLHVAPNNVMYVNQDIRRGLLGRMLAEILDTRVMIKKAMKEYPTNKSLLKLLDARQLSLKFIANVTYGYTSASFSGRMPGAEIADSIVLSGRETLERSIRFVNQNPKWNARVVYGDTDSMFVLLKGRTRQEAFEIGYDISETITRLNPRPVKLKFEKVYHPCFLVTKKRYVGSSYETPDQEEPIFDAKGIETIRRDGVPAVQKIMETCIKTMFRTQDLSLVKSYFVRQLGKILEGRVPIPDLMFGKEVRINSYSERGVLPPGAVVSARRMELDPRSEPQHGERVPYVVVYGSPGDRLTDQVVEPKELLLNKDLRLNGEYYIRKHIIPSMERIFQLAGADVKSWYEEMPRIQKAIPSSHPSTSWNTSTVSGVVTDPITNSAATVVPTETMAATIAAQNLRDQTSHMKMEANVLSDLGSATVAGTTLEAPAGPPRFKPRRRGGKGYVSVGPRIDRYYQSQLCVICNKMIIGQGPNKGKCRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T4I9</accession>
    <name>A0A9P6T4I9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Up-regulated during septation protein 1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_005022</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000025">
        <property type="protein sequence ID" value="KAG0024240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T4I9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029191">
        <property type="entry name" value="Uds1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15456">
        <property type="entry name" value="Uds1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Up-regulated during septation protein 1" evidence="2">
        <location>
            <begin position="297"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="670"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="680"/>
            <end position="693"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF15456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0024240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="757" mass="85695" checksum="68B203CB744952A8" modified="2023-09-13" version="1">MAKQASDTAFRTVKINRKASDNNLNASQKNGIYEQNPKVYLYQQHLQNATPARSHHRPQLCGDVSGDWAMNNQMLQSEPRRANEYYETLQHPPSIDRLRRNISLPDMKVGYKEAKERSAIRPPSPGELLPGQATNRSHSRPRVQPHHFIASATSDEPVMAIAIDDHEQRQSENSAEQIAHPQTPPTPQRSSSRTMRNHVIKSRTPHQDQTEEPQYQQQREGLITRHQILSDESLPEHAETLTAASNKELPPIPKKPAPPSLPVPSDTLMNGSCGLIPQDVFKNMDSQGVINAIKSTVIASRVYKVMTPEQLDILKKEQEELNDFVDSMHVSFHMESRMRDASHSLVRLHEDNLNLDALKDATTQLQATSRRMDRIFMQTQEAMRRLLSIQRSLLQHEGAVLNAGLRKLDSENRELSRTVMQLDAARGQEKEEKIKWKKEHNRLKFHSILFPGTPTQEGFTDKPAPSVDLQPAQQQHQARLASMETYIMELNDDILHKDEKITDLSNQLQAAKDWANDFESSVQSRKVACAESVQAGSDEPLQKRLHRLQSDIENEFKEMDVQTLELRSKVDSLSEEISALVCNSKALLAMNEESQAEARMYQARRAHRMKSHVRQDSDLRIVLQESLQELDRQIQLEESQRSPISRPSSTSTSATAYSFDFFDSNGISLSRRSSGKRSSGRSSRTHSSGSQSGLGLREQVLTRGFYLEDAQQESVLSGSSDDVSAEDTNVEIDRIDAMVKELKAIALQQNNEIEIDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T599</accession>
    <name>A0A9P6T599_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ubiquitin-like protease family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_005247</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000026">
        <property type="protein sequence ID" value="KAG0024209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T599"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070139">
        <property type="term" value="F:SUMO-specific endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016926">
        <property type="term" value="P:protein desumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.130">
        <property type="entry name" value="Ubiquitin-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003653">
        <property type="entry name" value="Peptidase_C48_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051947">
        <property type="entry name" value="Sentrin-specific_protease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46896:SF3">
        <property type="entry name" value="FI06413P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46896">
        <property type="entry name" value="SENTRIN-SPECIFIC PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02902">
        <property type="entry name" value="Peptidase_C48"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50600">
        <property type="entry name" value="ULP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Ubiquitin-like protease family profile" evidence="7">
        <location>
            <begin position="898"/>
            <end position="1137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="32"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="373"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="453"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="592"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1032"/>
            <end position="1098"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="50"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="110"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="120"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="169"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="195"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="260"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="278"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="298"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="318"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="346"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="373"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="388"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="409"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="474"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="538"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="626"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="661"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1042"/>
            <end position="1061"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0024209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1210" mass="134333" checksum="128CDBA6E2E64313" modified="2023-09-13" version="1">MGYEYILIVAAILIPLGLFSILRGEHTAGTHPIVKKTSLPGSFDDSTSSKSKKKPKKKKATAKGGSSQTAGNSAEKEQDSSESEVEVKAVAQPAKKNNVAATPAKSGKGLNEKGIKSSNDKSSLSANSKSNNDNTSKSKSKDSTADLPTAPLSSGRVVSDANKTAKPTSVEDWKKQKQEQQKELIAKQQDQLHFASAAARNASSDSSPHITSIPGSGAMGNNKKKNRSNAGSGLSHTEFPALSRPEPAPAQPKQPKQPKQKKEPVKKPEAEPVPEINQSEEENEKEDNQESRLQASGSDDDASRDDSEESEEEEEKWTTVNSTQSRSGGIDFNKPMDPWVAQQQRQRLERMAVADPHGEQTEKFARVLSIKPTVKEESIREAIPDGFQTQKSRSTGSSGGSSQYQSAELTKKQRENLAKAAKKKEEKAAMDAMQEKRRLEHMRQVKAEKMKEFYRAQTRKQTPVESRWDVPKTTAPSSSTQAETKGFNSDTEEPEYAVQLVSEPKTPSRSVQGRLIPSWNGKRIQKGIPIDVPKTQPRHSFSTEAPNPSLLTGYRDGGSSRRRSSTSTQSMSPFTGRNDEFAIIGQITGTMRSQNDKAKSKSTNVVLLSDEDDQRDQRNFKRKKVGGQSSGVVSSTTESSGGPLSIVARMKKHTPSKETTPRTTMYFPSTEPSSLNVRPTRPTRPTRPTRPTSPARIYPPTRVQQPTPVHAPLSVKAPALGMGTFPQATLTCVRLMNKVDFNTPGMTIQFGPDRLLINIDKNITRIPHHGLRFVEYNADGDLVILRIQTEDQLPSTSKLEPYYDPAPSSGKAKRIILFIKCDALFIEEQLRKLSEKGIDTSHLSSEIAAKIRSLESRSIRADASSTFAGDNKAANRASQHNETLFLFPFKSNSKSKSIAIQSEDISRLNEGEFLNDTLIEFGLKHVYANVEARNPDLADKTYIFNSFFYERLLTKSGKSIQYDSVKSWTNKIDLFSKKYIIIPIHENLHWYLAIITNPGLLLKTEEDTEPSSGSQMSLSYLDFDSNVSIDDIASPSLTNGDASKHPDELERESLVRSESRVSQETPPSQRHDDGPGPQKRKLRSMTPSVATPVDPEERKNIERTVDSKDVPGKLAKCPQQENFCDCGLFLLHYAEVFLKYPGPMLNGIVNRTDDMNRYWSVGDLAQKREKYREIMISLTEEYKSYLFSQKQIEQIKEANQHSNQSLNNER</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MC85</accession>
    <name>A0A9P6MC85_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_008975</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010005065">
        <property type="protein sequence ID" value="KAF9991669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MC85"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1530:FF:000002">
        <property type="entry name" value="Two-component osmosensing histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1530">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45339">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45339:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58104">
        <property type="entry name" value="Methyl-accepting chemotaxis protein (MCP) signaling domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9991669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="133" mass="14361" checksum="99BFA42E7018187C" modified="2023-09-13" version="1" fragment="single">MFANEVTRVAREVGTEGKLGVQAQVQDVRGTWKEITSNVNTMASEILDLKNTINSMVDQLSTFAVEVTRVAREVGTEGKLGGQAEVEDVGGTWKELTENVNTMASNLTTQMRDIADVSTAVAKGDLTKKITVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MCL4</accession>
    <name>A0A9P6MCL4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Pirin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_008524</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="4">Binds 1 Fe cation per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the pirin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004645">
        <property type="protein sequence ID" value="KAF9992507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MCL4"/>
    <dbReference type="OrthoDB" id="198735at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008127">
        <property type="term" value="F:quercetin 2,3-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02247">
        <property type="entry name" value="cupin_pirin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02909">
        <property type="entry name" value="cupin_pirin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.10:FF:000055">
        <property type="entry name" value="pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012093">
        <property type="entry name" value="Pirin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008778">
        <property type="entry name" value="Pirin_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003829">
        <property type="entry name" value="Pirin_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13903:SF8">
        <property type="entry name" value="PIRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13903">
        <property type="entry name" value="PIRIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02678">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05726">
        <property type="entry name" value="Pirin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006232">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pirin N-terminal" evidence="6">
        <location>
            <begin position="27"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="Pirin C-terminal" evidence="7">
        <location>
            <begin position="177"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR006232-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAF9992507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="261" mass="29352" checksum="90665A68DDEAAE8B" modified="2023-09-13" version="1" fragment="single">MTFTLARASRSIVKSVLSREQAEGAGARVRRSIGRPELRNHDPFLMLDEFNVDKNGGFPDHPHRGFETVTYMLEGQFQHEDFAGHKGTIGPGDLQWMTAGRGIVHSEMPVKSQTRAHGLQLWINLPKEHKMCEPQYQELLDKEIPRATPQEGVVVKVIAGESHGVTSKVYTRTPTMYLDYKMDKNKTVEQSIPSTYTGFIYMLKGKAYIGDKEFEGHAHHTLTLSEDGAETVKIQTKDEDAHFVLIAGEPLKEPIVQHGPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MDD9</accession>
    <name>A0A9P6MDD9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AMP-dependent synthetase/ligase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_008217</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004398">
        <property type="protein sequence ID" value="KAF9993226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MDD9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043041">
        <property type="term" value="P:amino acid activation for nonribosomal peptide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.38.10:FF:000001">
        <property type="entry name" value="Non-ribosomal peptide synthetase PvdI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.980">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.38.10">
        <property type="entry name" value="Luciferase, Domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020459">
        <property type="entry name" value="AMP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527:SF1">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45527">
        <property type="entry name" value="NONRIBOSOMAL PEPTIDE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00154">
        <property type="entry name" value="AMPBINDING"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="3">
        <location>
            <begin position="28"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9993226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="282" mass="30640" checksum="B460235FAB61E7D1" modified="2023-09-13" version="1">MPVQLDVTVLRFCAADENIADEQAGNLDLPCTSADTAYIMYTSGSTGRPKGVLTPHRAISRLVFNNRYADIGANDCVAMAANPAFDANTFEVWAPLLNGGRLVVIDFDTFANAHLLAEALDRHGINTMFLTTALFNLYVHTIGYALAKLKYLLCGGEQGNLETFEALCQLGGPQHLVSVYGPTETTTFATAYETQSADDQLERLPIGRPIGNTRLYVLDSYSRLVPVGAVGELYIGGDGVAKGYLNLPELTAERFLPDPFSKVPDARMYKTGDLVKYSNPNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MDE0</accession>
    <name>A0A9P6MDE0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Crinkler effector protein N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_008193</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Host cell</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004372">
        <property type="protein sequence ID" value="KAF9993305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MDE0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043657">
        <property type="term" value="C:host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045379">
        <property type="entry name" value="Crinkler_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20147">
        <property type="entry name" value="Crinkler"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Crinkler effector protein N-terminal" evidence="5">
        <location>
            <begin position="5"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="68"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="83"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF20147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9993305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="93" mass="10481" checksum="46E666182274972C" modified="2023-09-13" version="1" fragment="single">MANEVTLFCIVDGDSTAFSVDILPGKTVDHLKKKIKEEKSKVFSEVDPDELILWHVSIPSTPKRQITLGNLTDEEKDTKKPEELEDPTIEISE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MF31</accession>
    <name>A0A9P6MF31_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">COPII coat Sec23p-Sfb3p heterodimer component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">SFB3_3</name>
        <name evidence="4" type="ORF">BGZ80_007367</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003753">
        <property type="protein sequence ID" value="KAF9996017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MF31"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030127">
        <property type="term" value="C:COPII vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070971">
        <property type="term" value="C:endoplasmic reticulum exit site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090110">
        <property type="term" value="P:COPII-coated vesicle cargo loading"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1670">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.730">
        <property type="entry name" value="Sec23/Sec24 helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012990">
        <property type="entry name" value="Beta-sandwich_Sec23_24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007123">
        <property type="entry name" value="Gelsolin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036180">
        <property type="entry name" value="Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006900">
        <property type="entry name" value="Sec23/24_helical_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036175">
        <property type="entry name" value="Sec23/24_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050550">
        <property type="entry name" value="SEC23_SEC24_subfamily"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13803">
        <property type="entry name" value="SEC24-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13803:SF4">
        <property type="entry name" value="SECRETORY 24CD, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00626">
        <property type="entry name" value="Gelsolin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08033">
        <property type="entry name" value="Sec23_BS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04815">
        <property type="entry name" value="Sec23_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81995">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82754">
        <property type="entry name" value="C-terminal, gelsolin-like domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81811">
        <property type="entry name" value="Helical domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sec23/Sec24 beta-sandwich" evidence="3">
        <location>
            <begin position="27"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 helical" evidence="2">
        <location>
            <begin position="122"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="Gelsolin-like" evidence="1">
        <location>
            <begin position="251"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAF9996017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="396" mass="44442" checksum="9A0EA7ACE35345F0" modified="2023-09-13" version="1">MYPGFNVQRDGAKLIGNIAKLVGRPFGYNALMRVRCSTGLRIAEHLGNFHMKNSTDVELAGIDSEKAFGVLVRHDGKLDEKTEASFQVALLYTTADGFRRVRVHNFSTPVTTLMGNVFRWADMDTTINFLAKGAIAQGLTKPLKDVRDALTERCVKILSSYRKNCASSTAPGQLILPEAYKLFPCYALALLKSKPLRAARDINSDMRVYQMRLLNNMGVSESIAFMYPRMIPVHGMSEKDGTMDHTGRVFLPASIRVSYARLNPAGAYLLDNGEALYFWIGRDVSSEFLSDVFGVSSLDEIDPNMRYLPELSSPINTKLRAIASYMQAQRSRYLNLIIVRQGREQSELDFSNQLVEDKNNDAMSYVDYLCAIHRMIQNDGTSRQDGSSGLWNPRMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MFY1</accession>
    <name>A0A9P6MFY1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006906</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003440">
        <property type="protein sequence ID" value="KAF9997913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MFY1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040397157" evidence="1">
        <location>
            <begin position="19"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9997913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="137" mass="14474" checksum="10875B07D3D6AD5F" modified="2023-09-13" version="1" fragment="single">MRFATAATLLTLASSAIASSWKYMGGDLGLVGPAFNATFKAGDVIPLEYAFYTPKIVSLNTTTSTNSSTSVNTGTASITSLAWIGETGNQTLNIVFNNDRSSGLASTCLSTDLCTGTYYPKRIDLTIPSDVYPSNYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MHH0</accession>
    <name>A0A9P6MHH0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uracil-regulated protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">URG1_2</name>
        <name evidence="7" type="ORF">BGZ80_006353</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GTP cyclohydrolase II family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003130">
        <property type="protein sequence ID" value="KAG0000525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MHH0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003935">
        <property type="term" value="F:GTP cyclohydrolase II activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00641">
        <property type="entry name" value="GTP_cyclohydro2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10990">
        <property type="entry name" value="GTP cyclohydrolase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022163">
        <property type="entry name" value="GTP_CH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032677">
        <property type="entry name" value="GTP_cyclohydro_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000926">
        <property type="entry name" value="RibA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036144">
        <property type="entry name" value="RibA-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005536">
        <property type="entry name" value="PRK07198.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47259">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47259:SF2">
        <property type="entry name" value="URACIL-REGULATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12471">
        <property type="entry name" value="GTP_CH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00925">
        <property type="entry name" value="GTP_cyclohydro2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142695">
        <property type="entry name" value="RibA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GTP cyclohydrolase N-terminal" evidence="6">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="GTP cyclohydrolase II" evidence="5">
        <location>
            <begin position="155"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0000525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="336" mass="37594" checksum="41DA4997112CA54E" modified="2023-09-13" version="1" fragment="single">PPIEIKQQPQWSDPTKIVSLDPFGHLTNRYYKKEIESGLDIRPTIAITRAHMLVPEIQEIVRNGGLAVDGKIVMNETGELNVHKAAIDPVWYLPGVAARLNVEENVLRRSLFENSGGMYPELITRPDVKVFLPPIGGISVYIFGNHELLSDPNARLTVRVHDECNGSDVFCSDICTCRPYLIFGMREAIKEAQNGGVGLIIYFRKEGRALGEVTKYLVYNARKREGDSAAKYFTRTENVAGVKDMRFQALMPDVLHWLGVTKIDRFTSMSNMKHDALIDAGIKILERVPIPDELIPPDSKVEMEAKIAAGYFTTGHVPCDSELSRTVGRGWDDLQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MHN5</accession>
    <name>A0A9P6MHN5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RNA recognition motif-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">NOP4</name>
        <name evidence="8" type="ORF">BGZ80_006231</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003069">
        <property type="protein sequence ID" value="KAG0001118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MHN5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12414">
        <property type="entry name" value="RRM2_RBM28_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12416">
        <property type="entry name" value="RRM4_RBM28_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000406">
        <property type="entry name" value="Related to Nucleolar protein NOP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000182">
        <property type="entry name" value="RNA-binding motif protein 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051945">
        <property type="entry name" value="RRM_MRD1_RNA_proc_ribogen"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48039">
        <property type="entry name" value="RNA-BINDING MOTIF PROTEIN 14B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48039:SF5">
        <property type="entry name" value="RNA-BINDING PROTEIN 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="232"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="436"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="90"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="316"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="746"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="90"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="332"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="390"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="762"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="783"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="795"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="811"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="851"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0001118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="851" mass="94722" checksum="1F00CD52BD042FCD" modified="2023-09-13" version="1" fragment="single">AQLEAFFSEIGPVRSCFVVLDRSAEHAAAEEQEGEKNKAGIAAAAAAKAPLKNKGYGFVQFVLPDDADKAINDLRGVKFLKQRPLIMEKAVKKSHDGEEKPKKELKPKPKASKSKKANETTEESEEPKEKNYSFQTVVLKGLSKDITKKHIYKKVRKVGDVMEVIFPVYVKEPESTAEEEKSEKTVEEGTAHVIYNTAYLASSAVQALDGHIFKGCALHATLLASPSVYKRCRLIIRNLPWKYREAELRALFTKFGTVHDVNLPRKYEGGPLRGFGFVQMENLEATEKAVAALNGTEHHGRVIAVDWALAKDRFEEAEAKAQTEEAPQSTEQDQDVEMEDVSADNEADENEDGEDDEEDNEEGDDDDSEEEGSDNDDDEELDLEHLKGSDDEEAEDSDEEMDAEEEDAAALAALDAEEAQEKEQNKMALPDPSEGTTLFIRNLDFEATKDDLFELFRHWGKLRYCRVTMDHDTGRSRGTGFVCYFNKGAADNCMAEAEKVSAIVNPIQAENDRKKKNDFVKHTILQPDLPEELAVKFTLNGRVLNVVRAVDKKSAVNLLEAGQHKREREDRRNLYLMREGVIFPDSPAAAAILPSELSKRQASFSARRALLARNPSLFISKTRLSIRNLPLKMDEKELRKLGVQAIQKFKDEVKGGKRAHLSKEEQAEGWDKRVFVKQAKVVRSKDRVDAATQQLRSKGYGFLEYSTHAHALAGLRWLNNNPSLFGEKKCLIVEFSIENVMVNKQRTERETRRITKRKKGDDGEEEEEEQEEEVQEKKRPRRSIHEGGDRESRGGFRGGRGGRGGSDRGAPRGGFRGGSRGGPAGGRGGFRGGRGGGEGGRGGRGGSGGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MIV8</accession>
    <name>A0A9P6MIV8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Matrin-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_005727</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SF3A3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002815">
        <property type="protein sequence ID" value="KAG0003836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MIV8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000690">
        <property type="entry name" value="Matrin/U1-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003604">
        <property type="entry name" value="Matrin/U1-like-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051421">
        <property type="entry name" value="RNA_Proc_DNA_Dmg_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031774">
        <property type="entry name" value="SF3A3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024598">
        <property type="entry name" value="SF3a60/Prp9_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021966">
        <property type="entry name" value="SF3a60_bindingd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022755">
        <property type="entry name" value="Znf_C2H2_jaz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12786:SF2">
        <property type="entry name" value="SPLICING FACTOR 3A SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12786">
        <property type="entry name" value="SPLICING FACTOR SF3A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16837">
        <property type="entry name" value="SF3A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12108">
        <property type="entry name" value="SF3a60_bindingd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11931">
        <property type="entry name" value="SF3a60_Prp9_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12171">
        <property type="entry name" value="zf-C2H2_jaz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00451">
        <property type="entry name" value="ZnF_U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50171">
        <property type="entry name" value="ZF_MATRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Matrin-type" evidence="8">
        <location>
            <begin position="382"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0003836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="476" mass="55894" checksum="2040F7F3D2E318C6" modified="2023-09-13" version="1" fragment="single">TQRRLHEEIDRLEQAIVDQFMLNPKTHKERLLQEHTVDGYLDRISARSKDLQVLYKDEDGSRKKEMDAISGTNEFGEFYNRLKKVKDHHRRYPNEAVEPMELEFMDQQPTEAKMEALDEMFSGEEAGGRYLDLHEIHEQYMNLKSLKRTNYLGYLSEFTLFEEIQKKDKDAEYQNYINSLCKYLEGFLKRVKPLSNIGEIKEYSRKEFEKSWKEGTLPGWPKQDQEDTPSTDLFCIACKKQYAKDTVYNAHLTSKKHIKAAAQLTNGTSNGDEQESVKQVQSKVLSEKAKPDQDMASTEMLIRKYAEILKQQIEDTKENVERRQTLTGRERDLELETEQIELDESDSDDEEKVYNPLKLPLGWDGKPIPYWLYKLHGLGVEYSCEICGNYVYKGRKAFDKHFQEWRHAHGMRCLGIPNTRQFHEIVGIEDALALWNKIKKAKPEGTKRDQIEEFEDTEGNVFNKKTYEDLKRQGLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MJ20</accession>
    <name>A0A9P6MJ20_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Sorting nexin-4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Autophagy-related protein 24</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">SNX4_1</name>
        <name evidence="12" type="ORF">BGZ80_005635</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the sorting nexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002777">
        <property type="protein sequence ID" value="KAG0004314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MJ20"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005769">
        <property type="term" value="C:early endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000407">
        <property type="term" value="C:phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032456">
        <property type="term" value="P:endocytic recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061709">
        <property type="term" value="P:reticulophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015404">
        <property type="entry name" value="Vps5_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45949">
        <property type="entry name" value="SORTING NEXIN-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45949:SF2">
        <property type="entry name" value="SORTING NEXIN-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09325">
        <property type="entry name" value="Vps5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PX" evidence="11">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="85"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="240"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00040748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00041273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0004314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="327" mass="38001" checksum="8147D4DBD97E75FA" modified="2023-09-13" version="1" fragment="single">YVRGDRFNPEFIEKRRASLERFLKKIAVHPVLQRAECFRVFLDSRDWNSDLALQNKKRQDEGRLDTIGDALLNAFAKIKKPDEKFVIMRDEVDKLEENLQGLERLEQRILKRQEELEIDYREFGGAVAGLGNLETGITEPLHRFAHTVASYATILNELSTREDAEFLSELHECLAYCNSVKSVLKLRDQKQLDFEELSDYLQQQVAERQRLVSNGRLGGSASIGGFFQQKMDEIKGVDQERAKQDKLKRVEEKIKDLQDAVEKSSDDSDLFSNETAKEYEIFQLQKTKDMRQCLLDYTTGRVEFFEKGKDLWDQIIPVLEAIHVDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MKI2</accession>
    <name>A0A9P6MKI2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transmembrane protein 198</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_005376</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM198 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002655">
        <property type="protein sequence ID" value="KAG0005880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MKI2"/>
    <dbReference type="OrthoDB" id="102260at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025256">
        <property type="entry name" value="TM7S3/TM198-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040236">
        <property type="entry name" value="TMEM198"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31247:SF5">
        <property type="entry name" value="DUF4203 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31247">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 198 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13886">
        <property type="entry name" value="TM7S3_TM198"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="76"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="102"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="132"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="157"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="204"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="TM7S3/TM198-like" evidence="8">
        <location>
            <begin position="32"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0005880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="251" mass="26446" checksum="9655B9CD2AF7C5D6" modified="2023-09-13" version="1">MTQAAPVTEMDENDTNPSNGSDNVTVQGGIAGAILIIFGLTLCFFGYRFFHVTMYLVGFYFFANITYVIMANSGVTSPTLLLVISIVIGILGGLLLVCCSRLGIAVLGGFALYSLGLWILGWKPGGTIASPVGRGIFLGALSAVGFIIGFILERETVIIGTAIIGAYSIVAGIDFYAHTGFISEADLFINSKDNITQRVGSLSAGAYALLASFIVLAILGMVIQFKLWGRRTFRPAAASSTGNVVSTEKTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6ML73</accession>
    <name>A0A9P6ML73_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Inorganic phosphate transporter pho84</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">PHO84_6</name>
        <name evidence="8" type="ORF">BGZ80_005329</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002634">
        <property type="protein sequence ID" value="KAG0006237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6ML73"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24064">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 22 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="176"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="214"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="240"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="308"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="1"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="42"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0006237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="372" mass="42422" checksum="ECA7E9ABF4A4B187" modified="2023-09-13" version="1" fragment="single">KKIEADPRYLDYVWRCLIGLGCIPALVAVYFRLTIPETPRFVLDVENNLHKAEKDVAAALQTRNALQSDRDVVEDRNTQFNLINPRKNSLARPDYERTRYSDGTYASKRVFRDDRTTGSNFRDFCRYFSRWSTFKVLMGTSMTWFALDVAFYGIGLNNTSILSTISFGTDSKDAYTTMWSATVGQVIIVLLGAIPGYWVTVFTIERLGRIKIQVLGFVMSCILFCVLGFAYYPIKDSSPVLFVFLFAATQFFQNFGPNATTFIIPGEVFPTRYRSTGHGISAGMGKLGAIVAQVGFSRWKDIGGPNEFIPRLLQIFALFMFIGLIFTYFVPETKGKTLEELCGDEDYAERRLERERNLHNSLYEEKDDDDNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MLA3</accession>
    <name>A0A9P6MLA3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glutamate dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">GLUD1_2</name>
        <name evidence="13" type="ORF">BGZ80_005230</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-glutamate + NAD(+) + H2O = 2-oxoglutarate + NH4(+) + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15133"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.4.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-glutamate + NADP(+) + H2O = 2-oxoglutarate + NH4(+) + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11612"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.4.1.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7 11">Belongs to the Glu/Leu/Phe/Val dehydrogenases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002595">
        <property type="protein sequence ID" value="KAG0006542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MLA3"/>
    <dbReference type="OrthoDB" id="6718861at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004352">
        <property type="term" value="F:glutamate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006538">
        <property type="term" value="P:L-glutamate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01076">
        <property type="entry name" value="NAD_bind_1_Glu_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000100">
        <property type="entry name" value="Glutamate dehydrogenase 1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10860">
        <property type="entry name" value="Leucine Dehydrogenase, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006095">
        <property type="entry name" value="Glu/Leu/Phe/Val/Trp_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006096">
        <property type="entry name" value="Glu/Leu/Phe/Val/Trp_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006097">
        <property type="entry name" value="Glu/Leu/Phe/Val/Trp_DH_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033524">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014362">
        <property type="entry name" value="Glu_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033922">
        <property type="entry name" value="NAD_bind_Glu_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11606">
        <property type="entry name" value="GLUTAMATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11606:SF13">
        <property type="entry name" value="GLUTAMATE DEHYDROGENASE 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00208">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02812">
        <property type="entry name" value="ELFV_dehydrog_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000185">
        <property type="entry name" value="Glu_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00082">
        <property type="entry name" value="GLFDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00839">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00074">
        <property type="entry name" value="GLFV_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0520">NAD</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 7 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal" evidence="12">
        <location>
            <begin position="228"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="147"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="274"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="403"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalysis" evidence="10">
        <location>
            <position position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0006542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="511" mass="55730" checksum="7C1DA666DE80C985" modified="2023-09-13" version="1">MVVAILRRAPGTLASAVRLHRATFAAPTARFMSTHVTNAACEDHEPGFLGSVETYFDRAAKISGVSNKSLAAIRAVDSVLSVKFPVEIDADTHVIIEGYRAQHSRHRLPCKGGIRFSDEVDLQEVEALASLMTYKCAVVDVPFGGAKGGVKLNPKKFTPAQLERITRRYTMELCQKNFIGPGVDVPAPDVGTGPREMSWIMDTYRQFNPQDVNAAGCVTGKPISQGGVRGRNEATGLGVYYGVREFLQFPEVQKMSGLDGDIAGKTVIVQGFGNVGYWAAKFFQNNGAKIIGIGEHDVAAYDPNGLDIEAIFKHRSEKGTFRGFGNAEIIEEPIKVMERECDILIPAALERQIGLKNVKNIKAKIIGEAANGPITPDAHDYLVSQGKVVIPDLLLNAGGVTVSYFEWLKNLSHVRFGRMSRKWEEAGKNKLLTLVEENAGRQLTPQERRAVIHGAEEHELVYSGLEDTMIGACEETRATAALKNTDFRTAALVNAIQKISTVTAQSGQMFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MLG4</accession>
    <name>A0A9P6MLG4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">La ribonucleoprotein domain member 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">LARP1_1</name>
        <name evidence="5" type="ORF">BGZ80_005190</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002578">
        <property type="protein sequence ID" value="KAG0006639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MLG4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010494">
        <property type="term" value="C:cytoplasmic stress granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000339">
        <property type="term" value="F:RNA cap binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048255">
        <property type="term" value="P:mRNA stabilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045727">
        <property type="term" value="P:positive regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07323">
        <property type="entry name" value="LAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006607">
        <property type="entry name" value="DM15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045180">
        <property type="entry name" value="La_dom_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006630">
        <property type="entry name" value="La_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22792:SF132">
        <property type="entry name" value="LA-RELATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22792">
        <property type="entry name" value="LUPUS LA PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21071">
        <property type="entry name" value="LARP1_HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00684">
        <property type="entry name" value="DM15"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00715">
        <property type="entry name" value="LA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50961">
        <property type="entry name" value="HTH_LA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="HTH La-type RNA-binding" evidence="4">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="69"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="271"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="543"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="106"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="272"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="309"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="545"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="562"/>
            <end position="572"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0006639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="572" mass="64957" checksum="0AD8ED6152372DFE" modified="2023-09-13" version="1">MDAEGYVPLSFVANFNRVKNLTTDLALIKETLKSSKEIELNGDKIRRRGDWATWVFPTEDGAVPISSHRSTFVPPPRSPHPVVISSSLPTRPTTTTTNCGEDWHTKQSKSKKRNPIAHARPSSPAPQTAGSTADEDDEVFQFDDDHLLGSTRTGTVQKYYVSDDDDDDDDEFDDDTVAKILIVTQKKRDRSHGSYERKAMNDDINDMINEGLYHYEHDLQRKRNNINNINGVDSLGQSNKKVETVSEERFAAITGSQPRHANLILGASLGSQPALQQPHQQQQHQNQNGESSGRGKGKSKKNTAQRFYPLKEENKNAKGSKPDSRQHYAQAAVGWVLGDQPYLPTDLPSGSFSNSPATGLGIPMGSFADPSQLSTSMEVASSFPAFQHPSHELLHENGFIQHKYYKYHYKALKERKRQGIGHSQEMNTLFRFWSHFLRDNYNRKMYAEFKRLAVEDANANYRYGLECLFRFYSYGLEKKFRQDLFLDFEALTYADYQNGYMYGLEKFWAYLFFRKDKARRKLDVMAELRPLLEQFKSIDDFKNAQGKNQNPTNNNYATPTFGPGGGAGVQSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MMC0</accession>
    <name>A0A9P6MMC0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004848</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002428">
        <property type="protein sequence ID" value="KAG0007287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MMC0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="249"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0007287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="360" mass="39956" checksum="F6DA8EA026C72A83" modified="2023-09-13" version="1">MPGSTTRPWYPTFGPAITTSCSDSTIQLDNPNQFTLINNAKLNRHAVGPHWRSIQTSATYSPTPSPPASSPLLHSNTVAPSSLSSRLSTASTTTALHAYLSSTYSSAASIDYARATSFHQYDQTMTENKGTQQQPSHQEYYQSHSYPHDSRHHSMQSNQPSNSREARENMLVTNRLFLTPNTSATSHTGKRRATWQDEGDESDEDKNDSASPQAMQVFSSSENVSHPRTEQSSVQQFVPATVFTEQSTIVESGAPVSQDQEMRSAEKRLSTQSTTSSCVNRDVESMDQDDMEVVAETISTAEDRLVDTPQPRQVKRSKQRLDWTVYGIESVAEARRLQSGEQVKDIFQECFYNAAAPTSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNA7</accession>
    <name>A0A9P6MNA7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_004222</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002179">
        <property type="protein sequence ID" value="KAG0007786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNA7"/>
    <dbReference type="OrthoDB" id="8117402at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000110">
        <property type="entry name" value="Zinc finger protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050329">
        <property type="entry name" value="GLI_C2H2-zinc-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19818:SF139">
        <property type="entry name" value="PAIR-RULE PROTEIN ODD-PAIRED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19818">
        <property type="entry name" value="ZINC FINGER PROTEIN ZIC AND GLI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81995">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="475"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="507"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="538"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="357"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="11"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="380"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0007786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="586" mass="63991" checksum="848D36D9A0096295" modified="2023-09-13" version="1">MFTNSNSIGNPASTPVSAATSPAASPITVPSEAAALLQSLLHDNNIMPSSTNPNTFSRDFCLFEADEAQFDYPLFESIKMHPQHPLHPLQQLHAIQQHAQLQQQQQQQQQHVQLQNVQQQHVQQHQQAQHVLNSNSNPLCTPQTPSLDLLENARVTDSYGFDSFSAFLEESASSHSSASEAAVALIHVSDMASHLANVNGNGADLSTLHFSSSSSSHANHVLVDTPFTPYLDTPFETPYLSDFGEESESVNSAQVLFGHDNNGCGGSGINGVRGSSSGYSSVPLFHEFDFEIPANAHERCAYGNTIEPATLFMASPAVYHDLDDSQESDSSSCSISDISSAPASPFVLKAACKDSFDEGQTGQGGEDLDTSGSDISLSYEDNEEDEEDENEDVDQDDDDDEFIPSRPLAAAASGSTSGNKRKAPAATNYGRNPGSDKYTASASPFKRTRPELASPYGGKKKMSLKAKQSASNRRFPCKHPGCGLRFARLYNLHTHERTHDPHQIRPFICSTDHCRKGFSRKHDLQRHEASVHMGERNYRCQTCEKSFSRQDGLRRHLTVKSSSCAIANPNIHARAGDRNEPRWSAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNM0</accession>
    <name>A0A9P6MNM0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Lanosterol synthase (Oxidosqualene--lanosterol cyclase)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ERG7_2</name>
        <name evidence="5" type="ORF">BGZ80_003612</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the terpene cyclase/mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001969">
        <property type="protein sequence ID" value="KAG0008288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNM0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000250">
        <property type="term" value="F:lanosterol synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006696">
        <property type="term" value="P:ergosterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016104">
        <property type="term" value="P:triterpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.20:FF:000002">
        <property type="entry name" value="Terpene cyclase/mutase family member"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.120.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032697">
        <property type="entry name" value="SQ_cyclase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018333">
        <property type="entry name" value="Squalene_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01787">
        <property type="entry name" value="squalene_cyclas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11764:SF20">
        <property type="entry name" value="LANOSTEROL SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11764">
        <property type="entry name" value="TERPENE CYCLASE/MUTASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13249">
        <property type="entry name" value="SQHop_cyclase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="Terpenoid cyclases/Protein prenyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Squalene cyclase N-terminal" evidence="4">
        <location>
            <begin position="75"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0008288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="466" mass="52907" checksum="BA908141EF16AFA2" modified="2023-09-13" version="1" fragment="single">MTGGIINPIHAPTDRTRWRLRVDEGRQTWHYISEEESKANPQTDIDKYWLDLKLDAPQLTPAKTAIEAARNGFEFFKRLQNEEGFWSGEYGGPMFLIPGLIITYYITGAKIPEGWSQEIIQYLFNRADKQDGGWGLHIEGHSTVFGTALNYIVLRILGVDAEHPVCVRARGTLHKLGGATGSPSWGKFWMAALGVYDWEGMNPVPPELWLLPHIAPFHPARYWCHTRNVYIGMSYVYGRRATHPLTDLTRKLREELYTQPYDTIPWHQQRNNICKADEYYPHTRLLNFLNGGLVIAEKLTIKAGIRAHALKAAYAQVKYEDENTHYLDIGPVNKAMNMLATFYEEGKDSEAFKKHAANNVDFMWMSGGGMMMNGTNGSQLWDTALLIQGVVESGLALEPQNHESMKRALMFLDDCQIKRNPPFMKENFRDPTLGAWPFSNKFQGYTVSDCTSEGLKAVLLLQGKLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNT4</accession>
    <name>A0A9P6MNT4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyceraldehyde-3-phosphate dehydrogenase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">GAP1</name>
        <name evidence="2" type="ORF">BGZ80_003490</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001925">
        <property type="protein sequence ID" value="KAG0008403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNT4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046580">
        <property type="term" value="P:negative regulation of Ras protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05132">
        <property type="entry name" value="RasGAP_GAPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.506.10">
        <property type="entry name" value="GTPase Activation - p120gap, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000593">
        <property type="entry name" value="RasGAP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023152">
        <property type="entry name" value="RasGAP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001936">
        <property type="entry name" value="RasGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14149:SF17">
        <property type="entry name" value="GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14149">
        <property type="entry name" value="RAS GTPASE-ACTIVATING PROTEIN WITH IQ MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00616">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03836">
        <property type="entry name" value="RasGAP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00323">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143885">
        <property type="entry name" value="RGC domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00509">
        <property type="entry name" value="RAS_GTPASE_ACTIV_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50018">
        <property type="entry name" value="RAS_GTPASE_ACTIV_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ras-GAP" evidence="1">
        <location>
            <begin position="77"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0008403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="684" mass="77755" checksum="2FA696824EC7B625" modified="2023-09-13" version="1">MAIAEQREVAEHLEEADSSDGLFPDDRKLQSYGNLFFLLQTEPRHIATLCRLVSLTEIDTLLQTVMFTLYGNQYESREEHLLLTMFQSVLSAQFETATEFGSLLRANTPVSRMMTTYTRRGPGQSYLKTVLSERINSLIEHKELNLEVNPLKVYEQMINQIEEDTGSLPPHLPRGVPPEVAAANTDVQAIIAPRLSMLMEIANSFLDTILESLDQVPYGIRWICKQIRSLTKRKYPDATDFSICSLIGGFFFLRFINPAIVTPQAYMLVDGLPSKHPRRTLTLIAKMLQNLANKPSYAKEAYMMTLNPFVENNKARINKFLNDLCEVGDFYESLEMDQYMALSKKEINLHITLNELFNTHQLLSQHRDTLAPQEKHHLRVCLNELGAAPPQVPRKENKTIVLPLFSRWETPIQDLHSTFLQETNITQADIMYMETKSILVQLIRSIPGIADKRPLDLMKIAETAATTKDAILVRKGIKVKEMLIELEALNVVDDHFTFMTEEVTEELRHLGNLREKVNQEAASLEAVYKTIGDHNNYLRSQLDSYKAYLQNVRMQSGGGNSPGQGPGVGVVTVGGKEAKKGKQQVLGPFKFTHHQLEKDGVIAESNVPENRRSNIFFNITSPIPGTFIIALHYKGRDKAILEMDLKLDDLLEKQQDQVQLLDLEYVHFNVNKILALLTKTFIKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MP05</accession>
    <name>A0A9P6MP05_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CCD97-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_002841</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001721">
        <property type="protein sequence ID" value="KAG0009003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MP05"/>
    <dbReference type="OrthoDB" id="333176at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040233">
        <property type="entry name" value="CCD97-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018613">
        <property type="entry name" value="Ccdc97-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31840">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 97"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31840:SF1">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 97"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09747">
        <property type="entry name" value="CCD97-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CCD97-like C-terminal" evidence="2">
        <location>
            <begin position="264"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="291"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="365"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="493"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="560"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="195"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="231"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="365"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="378"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="404"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="414"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="512"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="563"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="597"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="618"/>
            <end position="628"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0009003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="628" mass="69790" checksum="917800F96F3B8E6F" modified="2023-09-13" version="1">MSLTRASIDSILQYLEPYLDTLQTGFPTSTRPNEPVLTVAQKRQKIEATLAKDPGIFLTKWGSVILYPRPVSPTEAQNGNYANGGPAPDSAKKILSARDVLDLFTPLASDYEVRYQLTKLYQQLQQLFEHDNFEARSLTPAMVSNDMEIEDSKEASKENQKPDKPEPDQSDLFARSIVSQSTRRNRRLNYLLRHLAPPSPSDLASASTPIPGSTGPRVTSRSGAGDGSSGGKNSSSSHGQDSQQHPTLASILSISGSMSNLSFSESTYFSDAEMEARAPKLYHQYIGRFMEGDDREDDDSSDTVESDGTEDGDSNKNNVRGVALDDNADDEGDGNRVRRLRKTSPKPFGKDVSLVDRILWSVDHPTRSRQRQEETNEVLGSQQRQRGGNHSQSNTGPAPSLARRNPEPEKQDSESEFEEEFDTESEVDDSEMAEESSMQLDSRKGPLKDIISNDDEIRAKISVTPPIPPDPIPGVISSTFASAAMTLEQPEERNMFASVNNGGDLDSDEDKELDRATANRKEDQEALRREFVLLMKQRFLDGLDRNFDYSVVDFDDSLDDLEQENHDGEDKWFDSEEEEVVGGSVPNRSSRVEQTTRARSNVSSKTAFDERVQAWENGAQNGSGEYDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPN0</accession>
    <name>A0A9P6MPN0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Inorganic phosphate transporter pho84</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">PHO84_1</name>
        <name evidence="7" type="ORF">BGZ80_002591</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001643">
        <property type="protein sequence ID" value="KAG0009251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPN0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24064">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 22 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="130"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="166"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="224"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="259"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="299"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="1"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0009251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="339" mass="36698" checksum="6F3B0E0839FA37C9" modified="2023-09-13" version="1" fragment="single">GVGNMAASIVTLVVLKIFETAIKSDTDNLDIVWRICVGVGCIPAVSTVYLRLTMPESPRYAMDVEKNPAKANDAISQAIAQGGQADQLNEIQIVDNDGTAPRRSQSKEFLEYFSYWENCKILIGTASTWFLLDIAFYGISLNQSFVISAMGFTGDGTVFSNLWRSTIGNLIVSCLGAVPGYFITVLTIEKMGRKTIQLMGFAVVTVLFIIMASAFHALQQNTGVFIFVFALSQLFMNFGPNSTTFVIPGEVFPTRVRATAHGISAASGKAGAILTTFAFPKLVDLGGPPGAHAFMNKMFAIFAGIMALGFILTFLIPETKGMTLEEIEERGLRKAGHQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPQ3</accession>
    <name>A0A9P6MPQ3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_003256</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001853">
        <property type="protein sequence ID" value="KAG0008610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPQ3"/>
    <dbReference type="OrthoDB" id="2449178at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="72"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="115"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="339"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="465"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="369"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="487"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="260"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="378"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="500"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0008610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="515" mass="57789" checksum="975894FC2243D608" modified="2023-09-13" version="1" fragment="single">MINSNTNAVNIIDASNTEATTAYNPQDHSDQQLPSSSSPPPTFFQRTRSRLVLFYKSIPYSTKRKSLRNIRLLILALSFVSLILDAITLSFEVRVMNLDWDTTQTQAAMLLTPDLLAMTMTLVLLMFTSDAICCCFGNIDDVMEQETMENQYHEEPYDYEEEEGEEPVHEEHHRQYRSTDQLDYSSSSHRQEQHQEQQQQQQQGLEYKEKKDKGRKQELYEEEEEEEEVLTRRGKSKVAFVNSPETIHETRMDQREAFGTSSPSDTPIIIITDTKTSNNTPNSTSAQPNADADASRSASIIPTPITDEKPEATTTTMEELPEETVVVDETARSRRLYTIFRIVFSIGLFVLAIYWPAINSPTPIGHLPNSGGPKYPPSRNSYTQGHESTNGTSYSYGDSNSTMALGARTRGSGYHNSNPNASPSTKGKSWSYAYSHFCALEQTFGDNQSASVYCQVKVIRPGVTYAWAVLLIIELCIAASAGDFSKNRGRPMRDSQSTETIDEENLSGDLDGVED</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQT6</accession>
    <name>A0A9P6MQT6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_001441</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001328">
        <property type="protein sequence ID" value="KAG0010489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQT6"/>
    <dbReference type="OrthoDB" id="439808at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd21608">
        <property type="entry name" value="RRM2_NsCP33_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048289">
        <property type="entry name" value="RRM2_NsCP33-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052462">
        <property type="entry name" value="SLIRP/GR-RBP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48027">
        <property type="entry name" value="HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN 87F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="18"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="89"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="110"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0010489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="120" mass="13186" checksum="493D9EA7E606D57E" modified="2023-09-13" version="1">MPVLRIPVVGCTPFVLSSKVFVGGLSWGTTEDSLRREFEKHGSVIDASVVKDRETGRSRGFGFVTFADEVGADNAIQVLNDTEFEGRRIKVDRASENSGNRRGGNHGRPGRSDGDWGRQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQY5</accession>
    <name>A0A9P6MQY5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Autophagy-related protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ATG8_1</name>
        <name evidence="11" type="ORF">BGZ80_001357</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle</location>
            <location evidence="1">Autophagosome membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Vacuole membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the ATG8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001303">
        <property type="protein sequence ID" value="KAG0010596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQY5"/>
    <dbReference type="OrthoDB" id="6738456at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000421">
        <property type="term" value="C:autophagosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031410">
        <property type="term" value="C:cytoplasmic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16128">
        <property type="entry name" value="Ubl_ATG8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000010">
        <property type="entry name" value="Autophagy-related protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004241">
        <property type="entry name" value="Atg8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10969">
        <property type="entry name" value="MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02991">
        <property type="entry name" value="ATG8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0072">Autophagy</keyword>
    <keyword evidence="7" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="6 9" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0926">Vacuole</keyword>
    <feature type="lipid moiety-binding region" description="Phosphatidylserine amidated glycine; alternate" evidence="9">
        <location>
            <position position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00037813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR604241-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0010596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="126" mass="14507" checksum="B7C9BC97CC5650A9" modified="2023-09-13" version="1">MVRSAFQQEHAFEKRKAEAERIRQKYPDRIPVICEKVDKSDIATIDKKKYLVPADLTVGQFVYVIRKRIKLSPEKAIFIFVNEVLPPTAALMSSIYEEHQDKDGFLYITYSGENTFGSDLETAESD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MR10</accession>
    <name>A0A9P6MR10_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 10">Mitogen-activated protein kinase</fullName>
            <ecNumber evidence="2 10">2.7.11.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">HOG1_1</name>
        <name evidence="12" type="ORF">BGZ80_001783</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.24"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="10">Activated by threonine and tyrosine phosphorylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.24" evidence="2 10"/>
    <dbReference type="EMBL" id="JAAAID010001414">
        <property type="protein sequence ID" value="KAG0010106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MR10"/>
    <dbReference type="OrthoDB" id="192887at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004707">
        <property type="term" value="F:MAP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051403">
        <property type="term" value="P:stress-activated MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07856">
        <property type="entry name" value="STKc_Sty1_Hog1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000049">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000050">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003527">
        <property type="entry name" value="MAP_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050117">
        <property type="entry name" value="MAPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008352">
        <property type="entry name" value="MAPK_HOG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038783">
        <property type="entry name" value="MAPK_Sty1/HOG1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24055">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01773">
        <property type="entry name" value="P38MAPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01351">
        <property type="entry name" value="MAPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="20"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0010106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="363" mass="41401" checksum="C8E79128DC5248CD" modified="2023-09-13" version="1">MAQFAKLSIFGTVFEVTTRYVDLQPVGMGAFGLVCSAKDELTGQPVAIKKIMKPFSTPVLSKRTYRELKLLKHLKHENIISLSDIFISPLEDIYFVTELLGTDLHRLLTSRPLDKQFIQYFLYQILRGLKYLHSAGVVHRDLKPSNILVNENCDLKICDFGLARIQDPQMTGYVSTRYYRAPEIMLTWQKYDVAVDIWSVGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVIKTIGSENTLRFVQSLPKREKIPLTTKFPNTDPVALDLLEKMLVFDPKKRINAGEALYHKYLEPYHDPDDEPVAAEVFDWSFNDADLPVDTWKVMMYSEILDFHHVDDSQSNFPAEDVSQAAQGFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MR75</accession>
    <name>A0A9P6MR75_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PB1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_001256</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001283">
        <property type="protein sequence ID" value="KAG0010698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MR75"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070971">
        <property type="term" value="C:endoplasmic reticulum exit site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048208">
        <property type="term" value="P:COPII vesicle coating"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000270">
        <property type="entry name" value="PB1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033512">
        <property type="entry name" value="TFG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15335">
        <property type="entry name" value="PROTEIN TFG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15335:SF7">
        <property type="entry name" value="PROTEIN TFG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00564">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00666">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54277">
        <property type="entry name" value="CAD &amp; PB1 domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PB1" evidence="2">
        <location>
            <begin position="16"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="210"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0010698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="272" mass="29385" checksum="F0C7491FB60E6BAE" modified="2023-09-13" version="1" fragment="single">MASYEGLRKLTLGDKPVIIKFKCAGTNLRVPIAQVPTFNELCFIVQRLFRSELSADLDNLVLRYEDDDGDLITVREDTDISHAISLSNLVKLTVNDKVTHPIVVPMEQLPKKLVGMDEKQTVAAVAVALIDLQERIGHALKVIQLQHPGSINSSTHTATTGTGGQQNKSANGGIGGDTQYTVESKPLVLSAESLDQLLEPRRNILTRQTSVSSQASSHQHALSPAMRNQGVSQPSLSNVGNQLQQQPTQPWTAQSTPTANGMQPSITSPVPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRF1</accession>
    <name>A0A9P6MRF1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_001292</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001293">
        <property type="protein sequence ID" value="KAG0010645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRF1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="57"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="F-box" evidence="3">
        <location>
            <begin position="187"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0010645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="649" mass="72235" checksum="0DA3BDBCF2B8E91E" modified="2023-09-13" version="1">MSGRNTPNVMAVKQRPSPYSRPTAKQPSIVAGQRQLGQLVSPKPSPVAALPVELVPVNDLVQLARKSFSAKDFAAAVQYLTRALTIAPKDINLLDSRAASFEKVGGFNDALTDAKAMIRNHPQNPKGYLRAGKILRLQQNFKSSTKIYVAGAERCDNSSKEYETLARIAKEMCAKLEDIAKAEARVLDPMDRLPYELIVVIFDKLSFTERVRCLTISKKWMSYLGSVRQFWQSIELARRIPSSYQIPHHSLYTPTQPDQESNNKVTNRTVLSLVKNTPPRALHLGCAQQLTGSLFTQLTKMRRTAALETLTLRMNPKVYEHEFSLFWSATPKLRFLDLHGCFGVTDGAVVSVLDRCPMLEELDISECRITEACFMINCAVPLSNMKKLIIGRWEVQFAKEGIDSLVSRFPNLVTLDIRTMRPRGIEALESIGQLKMLKHLYTDSIETSGEAVTTFVLQQWVAGIQNLESLQMNACKGVSDSMIQLIAAGSAEPGSTRRGWSHSLKMLDLSSSPYLTCEGLEFLRANPLPHLHTLILNKCSRVSEQGLRYAVASSGTELCRLECTGYSNVSDKLLFEIKDHCPKIEALHIANSGLVTGIGLMALVNERGRGLQRICVDDCSGVSVDAVERARAVLGENSRVLFRFHRSHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRK1</accession>
    <name>A0A9P6MRK1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_001016</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001225">
        <property type="protein sequence ID" value="KAG0011013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRK1"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0011013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="128" mass="13831" checksum="F9AFEE84C1D24D1E" modified="2023-09-13" version="1">MQSAKLESLANSLQLAPVREDFEMSSPFLGSTTRVGSVAVTLAPSAAPIANLGPKPTAPDRASDADLASREGAGAFSYHFDSFIKRLTDWHARAGSSMASEDLYALWSFTYSYQMLKSCSLLAIMQQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRS8</accession>
    <name>A0A9P6MRS8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">SURF4-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_000727</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SURF4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001159">
        <property type="protein sequence ID" value="KAG0011377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRS8"/>
    <dbReference type="OrthoDB" id="7859621at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005793">
        <property type="term" value="C:endoplasmic reticulum-Golgi intermediate compartment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045214">
        <property type="entry name" value="Surf1/Surf4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002995">
        <property type="entry name" value="Surf4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23427">
        <property type="entry name" value="SURFEIT LOCUS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23427:SF1">
        <property type="entry name" value="SURFEIT LOCUS PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02077">
        <property type="entry name" value="SURF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01339">
        <property type="entry name" value="SURF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="157"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="181"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="208"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="245"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0011377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="271" mass="30460" checksum="460CB81EF146DA9A" modified="2023-09-13" version="1">MDSVQEYSRKFEDIIDRIGQPIKPYIPAIARFLIVVTFLEDALRISTQFSDQLYYLNRHRGFPKGINHIFLIVNVLTMLSCSILVIARKHTEYAAAALFGVVVTQALGYGLIFDASFFLRNLSVIGGLLMVVSDSLNKRRQLFAGIPSITENNKRTYFQLAGRVLLIFLFVGFILHGSWSLTRVIGAIVGFGACVMVAIGFKAKWSAMFLVLFLSVFNIVVNNWWSVDSSHMQKDFLKYDFFQTLSIMGGLLLLVTIGPGGMSMDEKKKAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRS9</accession>
    <name>A0A9P6MRS9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001034</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001229">
        <property type="protein sequence ID" value="KAG0010985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRS9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0010985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="177" mass="20445" checksum="F26624381754B1A8" modified="2023-09-13" version="1" fragment="single">SEDDNKRQRKKLRKEPTRRDGSSSFNLAVNDRWIHDGDDVSSALLDYTKLYLEVGTECPDRPAKITTLAVHLSTAGNFLFAPLPLPHLEAQDVLDIYSVSSAFREKSSETIQDYLFSEWTKNRPPSDLLWRLEINYAQVVALWTRSDNQNEDTCMHDYFMPIFNCLQRPGVTRHPQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MST2</accession>
    <name>A0A9P6MST2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 11">Chitin synthase</fullName>
            <ecNumber evidence="2 11">2.4.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">CHS1_6</name>
        <name evidence="15" type="ORF">BGZ80_011799</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10 11">Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>[(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n) + UDP-N-acetyl-alpha-D-glucosamine = [(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n+1) + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16637"/>
            <dbReference type="Rhea" id="RHEA-COMP:9593"/>
            <dbReference type="Rhea" id="RHEA-COMP:9595"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17029"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="EC" id="2.4.1.16"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Cell membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the chitin synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.16" evidence="2 11"/>
    <dbReference type="EMBL" id="JAAAID010000996">
        <property type="protein sequence ID" value="KAG0012353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MST2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030428">
        <property type="term" value="C:cell septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004100">
        <property type="term" value="F:chitin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006031">
        <property type="term" value="P:chitin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04190">
        <property type="entry name" value="Chitin_synth_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004835">
        <property type="entry name" value="Chitin_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013616">
        <property type="entry name" value="Chitin_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914:SF9">
        <property type="entry name" value="CHITIN SYNTHASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01644">
        <property type="entry name" value="Chitin_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08407">
        <property type="entry name" value="Chitin_synth_1N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 11" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="540"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="584"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="615"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="662"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="797"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="829"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin synthase N-terminal" evidence="14">
        <location>
            <begin position="132"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="74"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="759"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="11"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU366040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF08407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0012353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="864" mass="98041" checksum="558F153CE5CED4FA" modified="2023-09-13" version="1">MPKQPQPVRKGQTQFSSQTPPMGQLDSAIPAFEIPSYSSYIRDPANLARHQSVYSTISRKSRASIITEPELDTENAYSYYPHQPPPRAKPEPEPEPAVQLQVFYPPPPSPPVLPPAPVIHNVIPERQERRYKTKKVVKLTNDNLVLDCPVPPHYLEKQIIQKGHEWEFMRYTAVTCDPDQFKAENYTLRPAMWNRETELFIVVTMYNEGVNLFAETMHGIMKNIRHLCSRNNSKTWGEGTWKKAVVCIVADGRKKCDPQVYNYLAAMGVYQEGVAKGEVNGKDVTIDPHMKVVESKSSDYVPVQIMFCLKEKNAKKLNSHRWFFNAFGPVIEPRVCVLLDVGTRPGPTSIYQLWKAFDLNSNVAGACGEIKPVKGTAAKNLLNPLVATQNFEYKMNNILDKPLESVVGYISVLPGAFSAYRYKALLTSPETPNEGPLISYFKGEKPSPDSGIFDANMYLAEDRILCFELVAKRNYAWTLRYVKAAWAETDVPDTVPELISQRRRWLNGTFFVALFSIVHFGKIYKSDHAYWRKLLFHLQLLYNVLSIFFSWFAIANIYLTFYILANSLTFPENSPYGRSDIFKIVFIVLKYFYEFLVIIVFVLSMGNRPTGSKLLYTAAMVFFAFLMVYMTFCAAWLTYLGISHALAAGETTLSAVIKDPTFRNVILSLASTYGLYLFGSILYLEPWHMVTSFVQYLCMMPSYVNVLNVYAFCNTHDVSWGTKGDNIDNMDLGVVKSGPKEGSGGEVTVSVPTEDHDINNSYQAALDSLKEKTEEKAQKRDSKTKQEDYYKAFRTRLVLLWCASNGLLVSIVTYSGTNGIGTYDTRSKNYLAFVLWSVAFLSAFRFVGSVAYIFLRLVSGELRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTG3</accession>
    <name>A0A9P6MTG3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Ataxin-3 homolog</fullName>
            <ecNumber evidence="4">3.4.19.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">Machado-Joseph disease-like protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="primary">ATXN3</name>
        <name evidence="22" type="ORF">BGZ80_011448</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Acts as a chain editing deubiquitinating enzyme that binds and cleaves 'Lys-48'-linked polyubiquitin chains, with a preference for chains containing four or more ubiquitin molecules thereby modulating protein degradation by the ubiquitin-proteasome pathway. Probably by regulating the IGF-1-insulin-like pathway, regulates lifespan. Regulates germline DNA double-strand-break repair and apoptosis in response to DNA damage by recruiting E4 ubiquitin-protein ligase ufd-2 to DNA repair foci. Interacts with key regulators of transcription and represses transcription. Acts as a histone-binding protein that regulates transcription.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 24">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="15">Forms a complex composed of deubiquitinating enzyme atx-3, adapter ubxn-5 and cdc-48.1. Forms a complex composed of deubiquitinating enzyme atx-3, E4 ubiquitin-protein ligase ufd-2 and cdc-48.1. Interacts (via RRDR motif) with cdc-48.1 (via N-terminus) and cdc-48.2 (via N-terminus); the interaction with cdc-48.1 is not required for atx-3 enzymatic activity. Interacts (via C-terminus) with ubxn-5. May interact with ned-8.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="4"/>
    <dbReference type="EMBL" id="JAAAID010000920">
        <property type="protein sequence ID" value="KAG0012891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTG3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.10:FF:000018">
        <property type="entry name" value="Ataxin-3 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.10">
        <property type="entry name" value="S15/NS1, RNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033865">
        <property type="entry name" value="Ataxin-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006155">
        <property type="entry name" value="Josephin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003903">
        <property type="entry name" value="UIM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14159">
        <property type="entry name" value="ATAXIN-3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14159:SF0">
        <property type="entry name" value="ATAXIN-3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02099">
        <property type="entry name" value="Josephin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02809">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01233">
        <property type="entry name" value="JOSEPHIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01246">
        <property type="entry name" value="Josephin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50957">
        <property type="entry name" value="JOSEPHIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50330">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 19" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="12" id="KW-0804">Transcription</keyword>
    <keyword evidence="11" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="8" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Josephin" evidence="21">
        <location>
            <begin position="12"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="178"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="239"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="322"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="180"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="207"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="245"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="20">
        <location>
            <begin position="273"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="active site" evidence="19">
        <location>
            <position position="25"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="18">
        <location>
            <position position="25"/>
        </location>
    </feature>
    <feature type="active site" evidence="19">
        <location>
            <position position="124"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="18">
        <location>
            <position position="124"/>
        </location>
    </feature>
    <feature type="active site" evidence="18 19">
        <location>
            <position position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00060106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00063584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00069055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00082365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR633865-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAG0012891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="375" mass="41324" checksum="6E40160436381FD4" modified="2023-09-13" version="1">MISLHPSHSFIVFFYVNEQQEGNLCAQHCLNALLQGPYFTAIDLAELARQLDQREQDALGNSGSGSRNVTSQNMDDSGFFSVQVISHALSIWNTQIIPWGAKEVSDAKSEPEREFSFICNLDQHWYTLRRFGPSTQRWYDLNSLHPQPQYMSATYLGMTLSQLEAEGYSIFVVRPLSKPDPSTTSVAKTPIVSQSEIKAKEATTDLPPESTSTPSAPAPSFLNERQEMERIRRQRIEERERVGKQQMSTLTSLSASPVASDTNDSNNSNKRIRVNDTEKTEKPSEDFIVSTPSFLPPCEADGMAAAMPLVQAPESQKLENQTFGGAGYRLGGSPPQSTAASASLPPGFSLEDADLADTEDEMMQQAIAMSLQGSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTG6</accession>
    <name>A0A9P6MTG6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_011531</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000939">
        <property type="protein sequence ID" value="KAG0012749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTG6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046331">
        <property type="entry name" value="GPAM1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46370">
        <property type="entry name" value="GPALPP MOTIFS-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46370:SF1">
        <property type="entry name" value="GPALPP MOTIFS-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="36"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="102"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0012749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="181" mass="19045" checksum="2C01C786A7611C32" modified="2023-09-13" version="1" fragment="single">MGIGPELPPHLQKNRAAAAHIESDNENASDDDQDNIGPSIGPSIGPSIGPSIGPSIGPSIGPSIGPSRPPAEEGPVASDDFAPALPPEMLEARRLAREKTQSSSSSSKPVLGPSLPPSMTTTATPSSSGSRGYYDDDESDDDDDIIGPVLPSNMDRDEMSKQSKIREFEERAERMRKKLAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTG8</accession>
    <name>A0A9P6MTG8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_000366</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001073">
        <property type="protein sequence ID" value="KAG0011880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTG8"/>
    <dbReference type="OrthoDB" id="2419911at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="245"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="28"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="74"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0011880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="445" mass="47883" checksum="089F71BEC1507057" modified="2023-09-13" version="1">MDAKQPANNDNSHNSSSSKGKGLLSERAGSGSTAGAQTGGMTNFVESITSSARNVVSALDPRQANILTQHDSHGSSSSLSNSAASGSTSKASTSSASRTFQHATSALETIGSSSVSDPTLGSMQPTGFRSTPSTFQQMGDAASANAGGAMDWDSFLASSESTIQDDQPYNPSSMSSSRFMSIASPTEMFLPQAHEQRPQQAQQHDSHALEPIYQARMSQSMNLTPANHAAFLEYLKSTASSTTTSSLAQPSQVAESGWSGSSFSNDIQRQQQMDGGQVLAFLDSTSYSDFVDQIEAEGVEKHQQVRREFVYSEATLGPQTQSLFSTLQLIQHLPSERQDIVEYLMQQGTYSEDVWGRPFGHDTNREEAASLAATLAEQDQFLHQQQQQRSIGGSDGDDAMTAEMERVLKQIVDDAKKEVKTGETNGKSLNRLMMVRSHITMGTKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTJ9</accession>
    <name>A0A9P6MTJ9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_011475</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000927">
        <property type="protein sequence ID" value="KAG0012835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTJ9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990234">
        <property type="term" value="C:transferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.80">
        <property type="entry name" value="E3 ubiquitin-protein ligase SopA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011044">
        <property type="entry name" value="Quino_amine_DH_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847:SF637">
        <property type="entry name" value="WD REPEAT DOMAIN 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141571">
        <property type="entry name" value="Pentapeptide repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50969">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="245"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="287"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="329"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="371"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="413"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="455"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="497"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="539"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="581"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="623"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="665"/>
            <end position="706"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0012835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="800" mass="86714" checksum="EE6C5814084652F1" modified="2023-09-13" version="1">MNQEQGSSRHGSASSVLSSEGRALIEGSSTILDRLLLEALFAKKGFLNDPSVSQYLVERAQQQPLFKQELLTIIERSKTEKAARIAAANAITVLVRAGVQFNRADLRGVRITGADLSYGVFDSALLDGADLQKTKLHNIWLRNANLMGVDMTGAQFGELAFLQEDDIVVRCAYWHGGKTLAVGLENGGLILYDISNWEKVLEIGGFDGRFGWLLHSETIDRAAYIDSDRGLRLVDVITGECLQILRGHTDEVSTIAYSPCGDKVASGGWDLTVRVWSIDAGECIHVLQGHTDGVSSLAYSPNGEMVVSASYDWDLRLWGVATGECIHVLQGHNGEIYSVAFSPNGGQIASAGQGSAVYLWDAETGNCTHNLQGHRGDVFVVTYSPNGSQIASGCDDKTIRLWDVETGDCIHIIQGHSLGVYCVAYSPDGSQISSGGQDKTIRLWDVESQFFERTIPGHAKGVRCVAYSPNGGLIASGSEDETVQLWDVETGKCVYNLQGHGGTVFGVSFSPRGDQVASGSQDMTVRLWNVETGSCVQTLEGHSNTVCRVIYSLNGNQIASGSDDHTVRLWDVESGECTHILQGHADEVYVVVYSLNGDQIVSGSRDSTVRIWDVETGICIRTLQDHGSPIYDVAYSPKGYQIVSAGEDGTVKLWNIETGSHIRTLQGHGDTVASLAYSQNGDQIVTGSYDMTAWLWDVETGQCLYVIAGFNGEVHGLAWKVTSNGQYLSTGSGDKSVRHWEIIKEQDEYSVRLCWSSSHDTLTVNDASFKGVRGLSQDNHILVSQCDALVDSNPSVSTIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTN0</accession>
    <name>A0A9P6MTN0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">L-2-hydroxyglutarate dehydrogenase, mitochondrial</fullName>
            <ecNumber evidence="7">1.1.99.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_000045</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>(S)-2-hydroxyglutarate + A = 2-oxoglutarate + AH2</text>
            <dbReference type="Rhea" id="RHEA:21252"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:16782"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="EC" id="1.1.99.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the L2HGDH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.99.2" evidence="7"/>
    <dbReference type="EMBL" id="JAAAID010001000">
        <property type="protein sequence ID" value="KAG0012336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTN0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047545">
        <property type="term" value="F:(S)-2-hydroxyglutarate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.460">
        <property type="entry name" value="YjbQ-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001602">
        <property type="entry name" value="UPF0047_YjbQ-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035917">
        <property type="entry name" value="YjbQ-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43104">
        <property type="entry name" value="L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43104:SF4">
        <property type="entry name" value="L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01894">
        <property type="entry name" value="YjbQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111038">
        <property type="entry name" value="YjbQ-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="9">
        <location>
            <begin position="80"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00036066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00041137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0012336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="481" mass="52337" checksum="BE23AD2BF868A5A0" modified="2023-09-13" version="1">MEMTLNEIAPESLPYVHADEGPDDMPGHVKSSLFGVSLNIPITNGRLNLGTWQGRSNSLQATHSALSHSPPQEPLQFEVDHLVIGAGVVGLAIAERLSARGAESTLLVEKNQLAGQETSSRNSEVIHAGLYYPQDSLKTRLCIRGNELMYEFCEKNNVEHRQTTKWVVGQNEADLVYLEGLSKKAEALLLPTKRMPGPATFIINEKQMLAEEPQVRGKAALVSPRTGIVDVHGLMSALEARIQDHGGDVILQCEVTGMERMHGQQNIRGGGGYKVDMMTPAGAATVKAATVINSAGLHADKVYNLLKQPYSTPPKDIGRVNHNVNSAEHPLPPLKLHYCKGHYYGYSGRALVSRLIYPVPDKNLTGLGTHLTLDLSGRMRFGPDTLYVEQFDDYFVDPSTVGSPESLELVSQVVASYLPAVKASALYADYAGIRPKLAGPGEPFRDFVIHHHDGFVNLAGIESPGLTSSLAIAEYVESMLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTQ1</accession>
    <name>A0A9P6MTQ1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Mitochondrial aspartate-glutamate transporter agc1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">AGC1_5</name>
        <name evidence="12" type="ORF">BGZ80_011547</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000940">
        <property type="protein sequence ID" value="KAG0012744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTQ1"/>
    <dbReference type="OrthoDB" id="269120at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45667">
        <property type="entry name" value="S-ADENOSYLMETHIONINE MITOCHONDRIAL CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="16"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="214"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="270"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="11"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="165"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="268"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0012744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="389" mass="42324" checksum="71A34ECCE11C2EF4" modified="2023-09-13" version="1">MPPTSLDPTKIDFQKYYFYGTILNIPPILAMYPMRTVRLLQQRKSSIPVSSSIFAVIKDVKRNNGVRALYAGATVFSIGLTSTKILQFASYDYLAQKIKENDHFGIEAIKNPSVLGGVLGTSSAVITTFFVVPFDMVSQQITLAKAGVQGKLVPSTVTNSATSVAPPIVPATGTAAASNIPIHVSGSRASLQPAQPMPISESLKLQLKQEGVRFLFRGYVATLMSAVPFFAAYFPAYEISKVWVKDGIQYVRSIQTKSENPFPPPESHQLIISSIAGSMASLAGVFVSSPSDMVKTRIQTEQRLQPTNGTGVKLPMPSLKWMDVFMEIWKKEGFLKFFAGTKARAILAVPGGALNFVIFDFVRSISTIKEPSMSMNQLPIPAEVMDGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTX6</accession>
    <name>A0A9P6MTX6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Exocyst complex component SEC15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_011625</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the SEC15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000958">
        <property type="protein sequence ID" value="KAG0012615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTX6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000145">
        <property type="term" value="C:exocyst"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006893">
        <property type="term" value="P:Golgi to plasma membrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090522">
        <property type="term" value="P:vesicle tethering involved in exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.670:FF:000002">
        <property type="entry name" value="Exocyst complex component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.670">
        <property type="entry name" value="Dsl1p vesicle tethering complex, Tip20p subunit, domain D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.30">
        <property type="entry name" value="Exocyst complex subunit Sec15 C-terminal domain, N-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007225">
        <property type="entry name" value="EXOC6/Sec15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046361">
        <property type="entry name" value="EXOC6/Sec15_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042045">
        <property type="entry name" value="EXOC6/Sec15_C_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048359">
        <property type="entry name" value="EXOC6_Sec15_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042044">
        <property type="entry name" value="EXOC6PINT-1/Sec15/Tip20_C_dom2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12702:SF0">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12702">
        <property type="entry name" value="SEC15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20651">
        <property type="entry name" value="EXOC6_Sec15_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04091">
        <property type="entry name" value="Sec15_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF025007">
        <property type="entry name" value="Sec15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 5" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Exocyst complex component EXOC6/Sec15 N-terminal" evidence="7">
        <location>
            <begin position="44"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="Exocyst complex subunit EXOC6/Sec15 C-terminal" evidence="6">
        <location>
            <begin position="398"/>
            <end position="739"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR025007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0012615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="773" mass="89621" checksum="DCF4015D1702D239" modified="2023-09-13" version="1">MAEFDIQQLVLVSDATNDAENLEHLGPTMKDVYRNDKMKPFLDQLGKFIRRKEMEIEKMCNSNYQEFVQSVDRLLKVRQGTVDLKDKIHILNTDVQRAGTELTAKKRELIESKRILENIATATETLRTCIHFLDLANRVNVQVENRKYYSALRIVDEIQVVHLRSVIQFEFARHMQDCIPILQHAIKDAVTTEMKEWLVSIRASQKTMGKIAMDRMAARQQRWRDRSNKGVRLKTTYNVNSAVEAAINEEKEVDILDADQVNLDLKPLYQCLHIYDELGQRAEFKASYAEDRRAQAKLTLSSITSSFNLKDRNTENFEALLHDIVGFFIVEHIILYTTTNFRAQSQLDELCELVTNLLLRLLSEGLANCQDPDMFLNVKLLLMLYIQTMESYNYPVSKLNDLLLTLFRTYADQLETKFSSNFHKLVDEDDYTPMLVENQDEYDLLQRSFRFKEDRKATRQGFPRTLPFSKVVPYCCEDIREFVRQFYRFVEGFNQEQNEMDDLVKDSLDTLLIQHVHSVWLKKLESRNLSQISQIIVNLEYFQGACGDFEQLLTEMRSTSDGTKVSLQASGLFRETRKSAEKRISELVNSKIDDILELAEYDWLPTSVQDLHSTYIQELVSFLSVVMSATLQSLPDSIRTFVYYDALEHLASQLHGIFTDPNVKHINQKFVTVFDMDVRYLEDFVATLDNPSVAQTFLPLRQLINLLVSEDTEEYMDPAIRSRNYAQVKSDEVTRMLEKLMTAPVAAATTQVETQMRSWGKVLEWGGIKSSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MU36</accession>
    <name>A0A9P6MU36_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">protein-L-isoaspartate(D-aspartate) O-methyltransferase</fullName>
            <ecNumber evidence="4">2.1.1.77</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BGZ80_011285</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">tRNA modification; wybutosine-tRNA(Phe) biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.77" evidence="4"/>
    <dbReference type="EMBL" id="JAAAID010000892">
        <property type="protein sequence ID" value="KAG0013101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MU36"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004719">
        <property type="term" value="F:protein-L-isoaspartate (D-aspartate) O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14733">
        <property type="entry name" value="BACK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000682">
        <property type="entry name" value="PCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018812">
        <property type="entry name" value="SAK_HAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11579">
        <property type="entry name" value="PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11579:SF0">
        <property type="entry name" value="PROTEIN-L-ISOASPARTATE(D-ASPARTATE) O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10307">
        <property type="entry name" value="HAD_SAK_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01344">
        <property type="entry name" value="Kelch_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01135">
        <property type="entry name" value="PCMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="BTB" evidence="12">
        <location>
            <begin position="458"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="411"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="411"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0013101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1229" mass="138350" checksum="57EFDCF7D6DEDB8B" modified="2023-09-13" version="1">MAWRCSGVSNSDLVNRLAEAKLIVSDSVKQAMLAVDRGNFSKFKPYEASLDVGSGSGYLTVCMAEMVGPQGRVVGVDHIPELVDLATENTMKDHPEYIQEGRIAYHSADGRVGFPQDDRYDAIHVGAAADSIHDELIEQLQAPGRMFIPACDGDGQAIFVVDKDKEGHVTKKKTMSVWAKEGVPPTKRYGHTAVLWKQNIIIFGGSNEFYEYRDDVIVFSLLTKTWSRPEIRGEVPARYLHSATVYKNKMYVYGGFAKNSKCTYVLEELRILNLETWTWSEAYSVPARYNHSACLVGNKLWIYAGKDETGNNVSDLHSIHLSTLRVLPHTGITGKVVLLKSQHFSEAIGNQLVVFGKYPNESTGTSLYGLWMMDLDQLEWRKLDIDSSLEDGVWNYFTVVTKRVQNHKRHELSSGEDLHQHNGTLDDIDDSNSAPSLIFLGNTEKDRPQPYDHFRDFSDFTIIPQDSTRKIHVHRMVLSSRWPHFRNMHASGMIESTRATMVLPEPYHVVYAFLSFLYTDVVDVDLDCTVLCEVMVMANMYLLERLKKLCASILHGHHLQVDTCVRIFQAACVSQEQGLKKLSQEFIYRHLGAVMKTEDWFLMWSQSGDGSSSEHRAAALEEFIEGVPEDAGLEIMSGSRRSNSCPFSLLGHPAVIHVNKRLLNHQESARLHTVHVFDFDQTLFRSPLPNPALWDTSFIGQMVSWNTCGPGWWHNPATLDLGPEAEASIWDGWWNEDLVAEITRSSNNPECLTILLTGRCGPVYNDQLIRMIQAKGLDFDLIVTKPTTAVWINPKVTSSNASKNKARANDGCYLKIHTFSFKHDFLYSVLLEYPSIQYMKVWDDRIGQIIKFQEAGKGWLEKKLLQTFEVQGVNIPHRFMDPEREIELVTAMVDIHNQQVAIEAKGGPLMVSGAAPMPPTRPELQDLGIWDPYETYIPQKRVRMDVAHVVQYTGILFSEGVQLFLKNIVQSEQGSGVWIQRPSAIRDQDISKWEVPHEMHIILCLGAAQPDFLDNIGGMGANVFVELVAVGELEGKIWALKVQGVDESTVEEDMLIVGPNGDIHTSFESLTSSYNDASGETPNLTFDSKARRGRVVLRKKGTPYITLAYDRFQGGRSSAASKITQWESIRETGFSKRIILVGTIGEKRLLGLKTKDLGHFATVPRAEVSIPMILKQRASEKDYLMQGKQLGQMLKGIEKEMERLSIANKIANIEAITILTHATIDEFFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MV45</accession>
    <name>A0A9P6MV45_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_010177</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000681">
        <property type="protein sequence ID" value="KAG0014882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MV45"/>
    <dbReference type="OrthoDB" id="2425721at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="259"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0014882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="323" mass="36027" checksum="A8B74CCD13A33C61" modified="2023-09-13" version="1">MTFTIAYPTTKPFSKAYSAVIAFLLAIGLIAMAIWTVETKKDCPTYTSPVFNNDKCTPYNLYNGVEVRKTYKPTGLIFGYKNSIEGLDSDFPYSNNSYSCQTVYYYRVVLNADRSTEINYNASCTFDNNVTFRLISNTVTNGVLFPWDADLWALTCPATIPRPYQLQSLIFASNDNGGTISTGFGFDSGVCTIPAWYDNQGHIAIFGPGYTPYAKNPITVDNYYQYKRNSTFSLFFGDDMGFQVGYTCSKCKVKSGWDLTLVLLTTFGSVGGIAYTILIFVAKNLYEHQSNTANYDEVALNKLRPDNGGSVDEWGGRDYTHVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MVV3</accession>
    <name>A0A9P6MVV3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_010318</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000704">
        <property type="protein sequence ID" value="KAG0014660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="901"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1979"/>
            <end position="2015"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="213"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="940"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="968"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="978"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1980"/>
            <end position="2015"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0014660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="2138" mass="239432" checksum="EE84D83D1F15183F" modified="2023-09-13" version="1">MTEVNQNEQSQAFRDCSSSEVYVIPTRVNKLGEHIILWEDVRQVFGPVKTVLNGKNAVLPMTDEQFQYLTPLRIPHYPGVVLDIVAEKGTITSNDTPQIVTTDPTPKAEQNTAINHIIEKDAQLSVEQESRIIVQPSTAENTHLAVWEPTLATKNPFNPDKRTSITPTTPQEFHQVYGSYFQDLMVGQVIQTSTLKDAMNKHFDSLQVEMYKNAALQARMLQLQQQMEEKQQKLIQMQHLTLNRLALIQNHVQLMLTQTYELHEYPIPRLFIVLPIPGQQRNELGRLQCNQFRLYFLCECGEHTMTPRSNTHEVHLALHEGYDLEQPSVFFEKYASYVLTLMQMFKYGVTTSGLVVPALDKFRIGMELDSIQNVPGGTNDKIDVLVDETISFLEECRDIAADDIDREGRSNSEQPLVLDSADLRQLESYLSIKDHDQALGNLYRVVTPEGHVKWVCIDHYHENYQESTILSLKEIVMANKGTIAEEEGRVEIKLTTGSQAKRFYQAMTKAPGGVQELKITLDWNVHLDDLRKLASAVTEAKVTHLTIDGFNFKGPARDVINRNRRYDPILQLMSNGSMRSLKIINFHNFFGHITSNSISMSPQQRVLWIDSNIKVGEKSFSSNLEKIIENCPSLTELRLKPLQTVAFIDLLVGKFNKALRFEFMTLRREGKDPEICMEFTRQMVRSSSVTLITNGRSILPKTDKQQRSTRPRLAVKINLDNWYDLLTIFRCYGWSIKELQIGGVFDDRHAKALSDSMADAGSKLSSLLVSTAHLTQGGLDGLLQVLDCSRALEILDLVFDIQDDSSSLKKLTSLIQRHRKRLHSLTVRGSYAGRWIPELAISFPSMQWFPRLESLEIVSKDRVLLSKSCIQWINDMVSGSSHGPMPPGSPQQTNRMSIVIPSQPHAQPPSPRSPILESPSGPLVPSRSPRVPNKFPIAGSSSDSLDLSRSPQRLSRTSVIGSSSDSLDLSRSRRVSDRASVGSSSDSLLFPGSPRLSNRNSLAVPSSESNRLKEFVLDGAKLQPEDWFTLIKALNFTTLERLGLPRTNFSFDQLRTLIACIEDATTTYNSLVILKTLDFRDTRISIGGDVDIMTNAGYSKGQSQSFHCIQTQETINIPLRADTATGEPVILLKDVAGVFGEVKHVRSGKNAVIYLTDENFNYLEPKRFKPYPGKILDVVLKDCGTVGKNLDLVVEKRNFAVEELDIAAAKGNVAVSLLNLAGRVEQDVTDSMASVAREISEIDVVDRPLSVVGTIETIEIPIEATGSPIEAVESPIGTFGNLIEATGILTNQENLQKPANMQEFHKMQTQRFEEAINNQRIQVASFTDALSAGSGLIQAEIHRYRDSQILIHQGQHRHDEQQDEQIRLALQFKKCVEAVISQNYDYGEGISPRLFIVLRRPTLPNNDSSEYRLFFLCECGSHTKSVSSSSGLPKVHLAIHIGYDIKRPREFIRKYGEYILAMMHMIKYGHSTDDIEIPSLENLDEASKNTIIECMEVDDRTTVESLVDNTTKYLITKEGVKSSGINIQAMTRLDLKHLHYYLKTKDNLYCGNLQIFVTKNGHVKWVCTDHRPDKQKGPHMVIWKKAIDSNNGKYDAQKGRANIKVSGKSVVEPLFEAMENFGGVNQLELAFGYNPSSSDLRTSATAITKSKIVHLTVNGGNIKGTTMKFIHRHRFNPILQMMNSAMLQQLRIEDFEDFFRHVNSSSEVDAPKLRVLMIDSAINCGGTRAAPVLANIIKNSPRLVELTLNSKDPSQLIKHLVDDTKAILKLEFLRIKEIQNESLEITLDFLRESAGTPRGVKVCIRAMKLGGAVVHQLSTVFKSYGTQIKELILFETDLMCRHYFAENLDAGTKGNTELTKLKLNLGLIPFEAIQQITQVINRSLKLENLTISIISSDDQVRQELVKELLSRHGSKLTGLTLRCNSYRGLIKELGNEFRTRHSFPNLESLQVRCDDGIILPDDCSSWIVAMASAAQPLERSPSSISSSSSSPSLPLSQDPAGSSSPSSSPSSSASSSSSSLASSLSSLHDSFSSGPAEADTIVPVKPLKVLLVDSYLSEAWWRTLIESIDFSALEILNFNHSNFGLQELDHLVTFMPDENHCTVPLRVINLIFTGVSDGPKYKEMTERLARKSSCQIRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MW73</accession>
    <name>A0A9P6MW73_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_010018</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000654">
        <property type="protein sequence ID" value="KAG0015159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MW73"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="22"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="69"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0015159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="112" mass="11990" checksum="6729D527F6AACD6C" modified="2023-09-13" version="1" fragment="single">MNPPPSWSKPASALGLSNPLNHLPQSQQVRQLQEQIQQHRRLQHQQSQGYSLGGHALKKKNSQGGTGGNNTNSSSGRGSAGNNQDRNGSFQQPFGGSGGHQHINIKNTDGMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWE5</accession>
    <name>A0A9P6MWE5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Oxysterol-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_009345</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the OSBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000550">
        <property type="protein sequence ID" value="KAG0016242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWE5"/>
    <dbReference type="OrthoDB" id="14833at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032934">
        <property type="term" value="F:sterol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.2720:FF:000001">
        <property type="entry name" value="Oxysterol-binding OBPalpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.2720">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037239">
        <property type="entry name" value="OSBP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000648">
        <property type="entry name" value="Oxysterol-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018494">
        <property type="entry name" value="Oxysterol-bd_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972:SF102">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01237">
        <property type="entry name" value="Oxysterol_BP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144000">
        <property type="entry name" value="Oxysterol-binding protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01013">
        <property type="entry name" value="OSBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="316"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="317"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0016242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="382" mass="43073" checksum="8B785AD194C1AB8C" modified="2023-09-13" version="1">MTDPNNNNAFDSDDTEVVDEGNRSILMDIISQLSKGGDLHRITLPTFVLEPRSMLERITDFMSHPEIIIKANQLEDPVERFVAVTQYFLSGWHIKPKGVKKPYNPILGEQFRSRWTFADGTEAFYVAEQVSHHPPISAYYYASPENNIRIIGDLKPKSKFLGNSAATLMQGEIKVSFTNRPGEDYFITMPNVYARGILFGTMLMELGDVASVKCPKLDLACSLEFKVKGYFGGTYNSIAGKIKRISTGEALYEISGKWSDEIYITKKGNKEIFFDAKTAKIHPKIVAPEEEQEANESRRLWSKLTAALKVNNQPLATEEKSKIEDAQRAKRAREEPGGVHLLRYFESKGDNYEIKLKDLSSDPQEAKKQIAEFVFNTPVPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWU8</accession>
    <name>A0A9P6MWU8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF431-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_009764</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000613">
        <property type="protein sequence ID" value="KAG0015588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWU8"/>
    <dbReference type="OrthoDB" id="373498at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035241">
        <property type="term" value="F:protein-arginine omega-N monomethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18090">
        <property type="entry name" value="Arginine_MT_Sfm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007364">
        <property type="entry name" value="SFM1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35517">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE SFM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35517:SF1">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE SFM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04252">
        <property type="entry name" value="SFM1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0015588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="223" mass="25160" checksum="55E753C45CCF1291" modified="2023-09-13" version="1">MAKNYIIEHMEEGMHEWCKLEYEHMISVCGPDHVYFTALTPRTLAGMPETLSKAHCHTEDILTMGDRIPHKKVCLLDPASPHVLSPEDGETYDFFLFGGILGDDPPRDRTGELRKLGFATRHLGPVQMTTDTALNVTRRVVEGKVPLDQIPFIDHPEIKLRKKETVTMPFRYIALPPKESAVEEAESSSSTKKSKKPKKPEPLLPPGMIELLIKDNDTALDMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXS1</accession>
    <name>A0A9P6MXS1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">5'-3' exoribonuclease 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="primary">RAT1</name>
        <name evidence="20" type="ORF">BGZ80_009158</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Possesses 5'-&gt;3' exoribonuclease activity. Required for the processing of nuclear mRNA and rRNA precursors. May promote the termination of transcription by RNA polymerase II. Essential for vegetative cell growth and chromosome segregation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Interacts with RAI1; the interaction is direct, stabilizes RAT1 protein structure and may stimulate its exoribonuclease activity. The interaction also stimulates RAI1 pyrophosphohydrolase activity, probably by recruiting it to mRNA substrates.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000526">
        <property type="protein sequence ID" value="KAG0016523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXS1"/>
    <dbReference type="OrthoDB" id="372487at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004534">
        <property type="term" value="F:5'-3' RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000956">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18673">
        <property type="entry name" value="PIN_XRN1-2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.1050:FF:000002">
        <property type="entry name" value="5'-3' exoribonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12390:FF:000003">
        <property type="entry name" value="5'-3' exoribonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12390:FF:000005">
        <property type="entry name" value="5'-3' exoribonuclease 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.1050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12390">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027073">
        <property type="entry name" value="5_3_exoribonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041412">
        <property type="entry name" value="Xrn1_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004859">
        <property type="entry name" value="Xrn1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12341:SF41">
        <property type="entry name" value="5'-3' EXORIBONUCLEASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12341">
        <property type="entry name" value="5'-&gt;3' EXORIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17846">
        <property type="entry name" value="XRN_M"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03159">
        <property type="entry name" value="XRN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 17" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-0540">Nuclease</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="12" id="KW-0804">Transcription</keyword>
    <keyword evidence="10" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0806">Transcription termination</keyword>
    <keyword evidence="16" id="KW-0862">Zinc</keyword>
    <keyword evidence="16" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="19">
        <location>
            <begin position="266"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="110"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="497"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="879"/>
            <end position="1048"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1093"/>
            <end position="1207"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="17">
        <location>
            <begin position="458"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="121"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="505"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="18">
        <location>
            <begin position="552"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="573"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="18">
        <location>
            <begin position="883"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="18">
        <location>
            <begin position="956"/>
            <end position="966"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="18">
        <location>
            <begin position="996"/>
            <end position="1006"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="18">
        <location>
            <begin position="1014"/>
            <end position="1029"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="1132"/>
            <end position="1141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="1152"/>
            <end position="1161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="18">
        <location>
            <begin position="1176"/>
            <end position="1189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="18">
        <location>
            <begin position="1198"/>
            <end position="1207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00046137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00046943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAG0016523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1207" mass="133066" checksum="F415E9F098A295D4" modified="2023-09-13" version="1">MGVPALFRWLANKYPKITTNVVEEQPKEINGVTVPIDITQPNPNNEENDYLYLDMNNIIHPCCKPEGKPPPSNEEEMMIAIFAYIERIVNMVRPRKMLYMAVDGVAPRAKMNQQRSRRFRTAQEAKEKAASEDAAWEELTAELKAQRPDHDTQQKFDSNCITPGTPFMVNLGKTLRFWVAKKLNEDPGWMNLKVILSDGSVPGEGEHKMMNFIRSQRAAPHHNPNTSHVIYGLDADLIMLALGTHEPYFKVLREDVFFQEGSSKNKCFLCNQTGHQAAQCQGKAKVKSGDFDEKAPATVKPYIYLNVSILREYLEVELKVENLPFEWDIEKAIDDWVFLCFFVGNDFLPHLPSLETREGAIDVLIEIWKQVLPLMGGYMTRNGDVDLKRAQLLMTELGKKEDGIFQERREKEERRMKNNKRRKVEDEARAMYASKEGGSALSQNSTWSLSAVAVRGLSDKAEAEKEVAALNKKIMEEKVRIRTASNQAAAALLKAELAQQDAPTEEVKDNATEDNKEDASSKEDTTVTAQTEDIQEDEAMTEFNPLKRTIDEVEESKDEADSVADEEDDDTEAAATPTPIPAAIAKKTVNDDEEPEDNVRLWEPEYKERYYRNKFHIELSDTEARRAIVKSYIEGCCWVMKYYMQGCPSWQWYYPYHYSPFASDFVDIGEIEIKFELGQPFHPIEQLMGVLPAGSKQHIPPAFQPLMYEEDSPIIDFYPENFELDLNGKKFTWQGVALLPFLDPKRLLDAMAPLYSKLTDDEVERNKFGKEVLFVSEKSKLYDFLCDKLYSSRSESEECYLDYKKSGRLLGNVSRDPQCIPRSSHPSPLVDYGLDDIPVDTSISVIFSNPPLPEGFVHQALMLKGVNPPKRVLSPDDIQWIKNGGGAQRGGRGGRGGRGGRGGYNNRGQSNGYNGGYDRNSRGGFSHRGRGGYTPENRGAADRTYPGQSYDRSHSQGGGPGFGAYNGGANNDGSRFPRSDPYYGYDSRPGHINYGGSRGGRGGYGDPGHRGGSHGRGGYSGRGGYGGGDQHSQGFGRQGSYDNAPNGGYGGGGPYDGYNRGGYGGHQGGGGGGYGNHPSGGYSGGGGGGSRGGYGGNRGGYNNNGPSGYPPAPHYPSQQAPIIPGFAPVNSYGPPAVAAPPYGAPVGGGYTGALPPGILPGQNPPPANGPAQGWYGHSGRGSGNRGRGGYNNVNNNLPPFPYPQQRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MY29</accession>
    <name>A0A9P6MY29_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphatidylglycerol/phosphatidylinositol transfer protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">NPC2_2</name>
        <name evidence="10" type="ORF">BGZ80_008286</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the intermembrane transfer of phosphatidylglycerol and phosphatidylinositol.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NPC2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000444">
        <property type="protein sequence ID" value="KAG0017444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MY29"/>
    <dbReference type="OrthoDB" id="6409159at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032934">
        <property type="term" value="F:sterol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015918">
        <property type="term" value="P:sterol transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.220.10">
        <property type="entry name" value="Ganglioside GM2 activator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036846">
        <property type="entry name" value="GM2-AP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003172">
        <property type="entry name" value="ML_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039670">
        <property type="entry name" value="NPC2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11306">
        <property type="entry name" value="NIEMANN PICK TYPE C2 PROTEIN NPC2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11306:SF0">
        <property type="entry name" value="PHOSPHATIDYLGLYCEROL_PHOSPHATIDYLINOSITOL TRANSFER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02221">
        <property type="entry name" value="E1_DerP2_DerF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00737">
        <property type="entry name" value="ML"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040484441" description="Phosphatidylglycerol/phosphatidylinositol transfer protein" evidence="8">
        <location>
            <begin position="20"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="MD-2-related lipid-recognition" evidence="9">
        <location>
            <begin position="21"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0017444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="146" mass="14771" checksum="203981129B268C7D" modified="2023-09-13" version="1">MKFIASAVAAIALATTVSADFTSCGSPNDTLTLSNVSYTPNPPKVGQQVCITLNGTLSAPVTQGSNLTVTATYMGFNVYSGTSDLCADLANSTTPCPIGTNVTSVTECVNVPSVIPTNATFNLQANATSASGAQIFCISGNLTFSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MY38</accession>
    <name>A0A9P6MY38_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Peptide hydrolase</fullName>
            <ecNumber evidence="13">3.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BGZ80_009041</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">May be involved in vacuolar sorting and osmoregulation.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Vacuole membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the peptidase M28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="13"/>
    <dbReference type="EMBL" id="JAAAID010000513">
        <property type="protein sequence ID" value="KAG0016670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MY38"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053975">
        <property type="entry name" value="PFF1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="METALLOPEPTIDASE M28 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147:SF58">
        <property type="entry name" value="VACUOLAR MEMBRANE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22250">
        <property type="entry name" value="PFF1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="15" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6 13" id="KW-0645">Protease</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0926">Vacuole</keyword>
    <keyword evidence="9 13" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="466"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="572"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="605"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="639"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="673"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="708"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="746"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="776"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="16">
        <location>
            <begin position="228"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="domain" description="Vacuolar membrane protease C-terminal" evidence="17">
        <location>
            <begin position="805"/>
            <end position="1028"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="501"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="515"/>
            <end position="530"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU361240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF22250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAG0016670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1041" mass="115832" checksum="A5F1DFD05D15DE5F" modified="2023-09-13" version="1">MNSPMPITSRANRRRAPSLESTTTPLLASIPQRKSDRRVRDEAAQRTHRMYVVSTHQFWSIYTVLALLYLGVVGIVYLARRPNAFVPPLPDMAPSETAPEIFNPFTAWEHLEAITTEPHPFNSRANTDVVKKYIINQFKTLQAEAIALGRRNVRYYDREDNTTWTELRKSSQQRRMEDLGEIEPNEGETLKPEVLSVVQGDNLIMWVGGVTESMEGDIPVKIEIDVDQESQAALMVSAHYDSVPSSYGATDDGGGIAVALAMIQHFIHHPVQHTLIFNLNNAEELGSYGAAAFMGAPKNSTTETGDGHPWKKYVRAFINLEGGGSGGPSLLFRATDHDIIRHYVDNAPFPHASVFINDVFQFELINSDTDYSTFIEHDIPGLDIAFYQRRSMYHTITDTLPIQSLFHMGSNAQATIAGLCNSDYLDSLAPSAKLQVDPVPVSPRSWFAGKSVFFDFLGKQMIYSDLWTTLLINALAIGLGLPVLASTVTYVGRAIRRRQHNRRPARLVDPNPTPSLRSVLHSSSTSVGNSEDGYGSVPTRSNNFRQHGRYTDSIDATQHGQPKKAAIARATALVALIVMFDLGAVVGASRWQYYVNPMARYSHPWLILAGLAWLLLVVNTFVVYLATLIESSIYEPVPILSGATLWTFAVGVWWWLVALAIGTGVAGWFGVGALYGTTVLAAFAGVSALIQIILNFSNPTEGIDDSRLGWILVLGLGLIVPGVVVLDMAVTVVYATSQSVIGGDTGMMYIIYGILLIPVLLPTVPVISRGRNFKKALWWELIVLALVAWWLSQAKPYSANEPATLYFYQLYNQTSRSSIVDLRTDATSGYLGRMVQDVPSLSTLASPSKCIPEPIEDGGEYTEACQFEPVRQIFEDDGKDQPLHIEWIKIPESGPDGWREGRLQVLALESRACSIYLAETSPGRETQIWMESEGSIVDRENHAKLQDNHRPKSLHAYVRDWNQPWSAVIRMREPDQSEEIGNGNKTSHEPVAIKVVCAYNDWYSDPGYASVYNEIRAHIPSWTRLRMYKRDLFEVGVDMTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYS0</accession>
    <name>A0A9P6MYS0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_007465</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell envelope</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000383">
        <property type="protein sequence ID" value="KAG0018192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MYS0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02966">
        <property type="entry name" value="TlpA_like_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050553">
        <property type="entry name" value="Thioredoxin_ResA/DsbE_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42852">
        <property type="entry name" value="THIOL:DISULFIDE INTERCHANGE PROTEIN DSBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42852:SF6">
        <property type="entry name" value="THIOL:DISULFIDE INTERCHANGE PROTEIN DSBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0201">Cytochrome c-type biogenesis</keyword>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="5">
        <location>
            <begin position="91"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0018192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="225" mass="25842" checksum="B4C9B2A7440F9A9D" modified="2023-09-13" version="1">MAEEIPEEKKTALLDAYVEILVSPFAEKYKETWEEETFWEAVEVFKAKTREIGIENPFDVLSKYKLVSYEMIRDKRKAGPPAFTRRNWKSPLVGEKVDVLGLVEKLHHISGSKYEGKEDIVVLDFWATWCDPCIVLAAELSKLAEKHIGRVAVIGINNDTPAKQRDVERIGAFFEEHREKIRYMSYVDNAENFAKSLGGTITYAGGENWFNARFEEALETSCHEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZ30</accession>
    <name>A0A9P6MZ30_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Chromatin modification-related protein EAF3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Chromatin modification-related protein eaf3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">EAF3</name>
        <name evidence="15" type="ORF">BGZ80_005995</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Involved in deacetylation of histones, chromatin assembly and chromosome segregation. May act as a transcriptional oscillator, directing histone deacetylases to specific chromosomal domains. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Component of the NuA4 histone acetyltransferase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MRG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000296">
        <property type="protein sequence ID" value="KAG0019311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZ30"/>
    <dbReference type="OrthoDB" id="124855at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035267">
        <property type="term" value="C:NuA4 histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032221">
        <property type="term" value="C:Rpd3S complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.274.30:FF:000004">
        <property type="entry name" value="Putative Chromatin modification-related protein eaf3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.30">
        <property type="entry name" value="MRG domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008676">
        <property type="entry name" value="MRG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038217">
        <property type="entry name" value="MRG_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026541">
        <property type="entry name" value="MRG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053820">
        <property type="entry name" value="MSL3_chromo-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10880">
        <property type="entry name" value="MORTALITY FACTOR 4-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10880:SF15">
        <property type="entry name" value="MSL COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05712">
        <property type="entry name" value="MRG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22732">
        <property type="entry name" value="MSL3_chromo-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038133">
        <property type="entry name" value="HAT_Nua4_EAF3/MRG15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51640">
        <property type="entry name" value="MRG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Chromo" evidence="14">
        <location>
            <begin position="23"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="81"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="110"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00057322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00072864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0019311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="291" mass="33943" checksum="E917F0F37DAF9EF3" modified="2023-09-13" version="1">MTSKRQMTFEANETVLCFHGPLLYEAKILKTDWRSLDPPHGEEGPVYLVHYRGWKQTWDEWVPESRALKWNEANLAKQASLKESYPGKKKAVPKTSGSTESSDRGKKRAKDTSVDKEEEFTKRPEIKVPIPDSLKAQLVDEWENITKNQQLVPLPKTPNVVQILDMYRDSKKDKKTKNDEIFQEVLSGVKTYFDKCLGNMLLYRFERQQYVDIRKKYPGKEDSEIYGGEHLLRLFVQFPMLIAHTQMDQDSINALRENLVDILKWMQKNHKDLILSEYENASPAYQSIVKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZB9</accession>
    <name>A0A9P6MZB9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Adenylate kinase</fullName>
            <ecNumber evidence="6">2.7.4.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">ATP-AMP transphosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">ATP:AMP phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Adenylate kinase cytosolic and mitochondrial</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Adenylate monophosphate kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 9" type="primary">ADK1</name>
        <name evidence="9" type="ORF">BGZ80_006719</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>AMP + ATP = 2 ADP</text>
            <dbReference type="Rhea" id="RHEA:12973"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.3"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="6">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
            <location evidence="6">Cytosol</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Mitochondrion intermembrane space</location>
        </subcellularLocation>
        <text evidence="6">Predominantly mitochondrial.</text>
    </comment>
    <comment type="domain">
        <text evidence="6">Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the adenylate kinase family. AK2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.3" evidence="6"/>
    <dbReference type="EMBL" id="JAAAID010000333">
        <property type="protein sequence ID" value="KAG0018802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZB9"/>
    <dbReference type="OrthoDB" id="439792at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004017">
        <property type="term" value="F:AMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006172">
        <property type="term" value="P:ADP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046033">
        <property type="term" value="P:AMP metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046034">
        <property type="term" value="P:ATP metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01428">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000106">
        <property type="entry name" value="Adenylate kinase mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00235">
        <property type="entry name" value="Adenylate_kinase_Adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03168">
        <property type="entry name" value="Adenylate_kinase_AK2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006259">
        <property type="entry name" value="Adenyl_kin_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000850">
        <property type="entry name" value="Adenylat/UMP-CMP_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033690">
        <property type="entry name" value="Adenylat_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007862">
        <property type="entry name" value="Adenylate_kinase_lid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028587">
        <property type="entry name" value="AK2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01351">
        <property type="entry name" value="adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001380">
        <property type="entry name" value="PRK00279.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001381">
        <property type="entry name" value="PRK00279.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF011100">
        <property type="entry name" value="PRK14527.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23359">
        <property type="entry name" value="NUCLEOTIDE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00406">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05191">
        <property type="entry name" value="ADK_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00094">
        <property type="entry name" value="ADENYLTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00113">
        <property type="entry name" value="ADENYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Adenylate kinase active site lid" evidence="8">
        <location>
            <begin position="176"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="NMPbind" evidence="6">
        <location>
            <begin position="78"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="LID" evidence="6">
        <location>
            <begin position="175"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="58"/>
            <end position="63"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="105"/>
            <end position="107"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="134"/>
            <end position="137"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="185"/>
            <end position="186"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="248"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF05191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0018802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="265" mass="29192" checksum="FEA7CCCE09B8E2EA" modified="2023-09-13" version="1">MAPVNDTTPGPSPLSDIKNLLKQLHEKVDRLEAKVEAKVSGKDQDPKTLRMILIGPPGAGKGTQAPKIKEKFCLCHLATGDMLRAAISNKTKVGLEAKKVMDAGGLVSDEIMVDMIKDNLENNKECKNGFILDGFPRTVVQAEKLDAMLDAKNQHLDTVIELSIDDNLLVSRITGRLIHVPSGRSYHKEFAPPKVPMKDDITGEPLTQRSDDNAEALKKRLVAYHKQTVPVVEYYKKKGLWSQVDAAQDPKLVWSSMSAIFSKVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZG3</accession>
    <name>A0A9P6MZG3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Arp2/3 complex subunit, actin nucleation center</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ARP2</name>
        <name evidence="8" type="ORF">BGZ80_007530</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the actin family. ARP2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000388">
        <property type="protein sequence ID" value="KAG0018111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZG3"/>
    <dbReference type="OrthoDB" id="5132116at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034314">
        <property type="term" value="P:Arp2/3 complex-mediated actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd10220">
        <property type="entry name" value="ASKHA_NBD_Arp2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000050">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000005">
        <property type="entry name" value="Actin-related protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020902">
        <property type="entry name" value="Actin/actin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00190">
        <property type="entry name" value="ACTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01132">
        <property type="entry name" value="ACTINS_ACT_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0018111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="392" mass="44391" checksum="BFD97D5AD6F18725" modified="2023-09-13" version="1">MESSKTIVVDNGTGFVKVGYAGSNFPEHVFPSVVGRPILRAEESIGNVRVKDIMVGDEAAELRAILQMSYPMENGIVTNWTDMRHLWDYTFNEKLKIDPRDTKIMLTEPVMNPKANREKMVQTMLEEYGFQGVYVAIQAVLTLYAQGLTTGVVVDSGDGVTHIVPVVQGYSLPHITKRLDVAGRDVTQYLIKLLLHRGYAFNRTADFETVRQIKEKLCYTSYDVDLDLKLANETTVLVESYTLPDGRVIKVGSERFEAPECMFQPGLIDVEQPGVAELLFQTIQSAPLDTRSELYKHVVLSGGSTMYPGLPSRLEKEVKQLYLTEVLKGDVERFRNFKIRIEDPPRRKHMVFLGGAVLANIMQDKEHFWISKQEWEEQGVRALDKLNIVQSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZV6</accession>
    <name>A0A9P6MZV6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_004918</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000246">
        <property type="protein sequence ID" value="KAG0020007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZV6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF284">
        <property type="entry name" value="EG:103B4.3 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="94"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="158"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="199"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="235"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="265"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="289"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="327"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="361"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="5">
        <location>
            <begin position="201"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="38"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0020007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="389" mass="41287" checksum="AEEBA3FF5FCD5B76" modified="2023-09-13" version="1">MTVSTINSPHPISVAATVTSGSSIKLDTASSEMTTTDLTINSTSPQDLGFPIEKIEPTAGSDDEKPEYMIDNDDMEGIAVAREPDAMTFPDGGFGWFVGLMYGLGAGMALFTSVAIPVQWFEKKRGLASGITVAGSGIGGATLAPLNRLMISKIGYQWALRIMGILVITLVCSILVCLRTRVTPSVKKRPLLDVTMFKNSGFTAMYFMGMLVTFGYLTPIFLFPNFVTDLGMDPTIGASLVSGFAGVNAFSRIALGFIGDRFGPLNVLIVSTIFTGLCCWVLWMNTHGLAMAVVFMVIYGSNAGGFNSLFLVVAANIIGVESLAETIGLLFSGNLFGNLLGSPLASAIVTASGGSYTWAQVYSGAAPMLAAVLLIVLRFKKDRRILVKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N034</accession>
    <name>A0A9P6N034_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein uL30m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_006520</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL30 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000322">
        <property type="protein sequence ID" value="KAG0018947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N034"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01658">
        <property type="entry name" value="Ribosomal_L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.20">
        <property type="entry name" value="Ribosomal protein L30, ferredoxin-like fold domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036919">
        <property type="entry name" value="Ribo_uL30_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005996">
        <property type="entry name" value="Ribosomal_uL30_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016082">
        <property type="entry name" value="Ribosomal_uL30_ferredoxin-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01308">
        <property type="entry name" value="rpmD_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15892:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL30M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15892">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00327">
        <property type="entry name" value="Ribosomal_L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55129">
        <property type="entry name" value="Ribosomal protein L30p/L7e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL30-like ferredoxin-like fold" evidence="5">
        <location>
            <begin position="40"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0018947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="220" mass="24137" checksum="C044F83403DEA45A" modified="2023-09-13" version="1">MSSVSRIISAARPTFTASARAYTTSTATSEAAPAASTGHYKVTRTRSLIGVPKSTIKVLKSLGLGRKIGRPVFQPHEPRAAGKILKVKELVKVENMPGPIPPEGYQRTRATKGYKVVGKIVAASSVSDLDVHLDYPSRTELLANCLQQQLQNYQKYVDVKDGICEARLIELKAQFEKVLRHLADNTGEKIIVEILLVITKLPLPGQFSRPKDAEQFALFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0X2</accession>
    <name>A0A9P6N0X2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Nadh-ubiquinone oxidoreductase 12 kDa subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_003000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000177">
        <property type="protein sequence ID" value="KAG0021118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0X2"/>
    <dbReference type="OrthoDB" id="10252718at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039993">
        <property type="entry name" value="NDUFB10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13094:SF1">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13094">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE PDSW SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0249">Electron transport</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0021118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="101" mass="11780" checksum="4120E087BE20EECD" modified="2023-09-13" version="1">MTTTADSWEYPAHRKFDNVVPLSEVDPEDKAAVLRSRALAVRESWIKAMEGRIVQKELKKCFRAEGVNHYENCRHLVDLYMTSLKEKRVEGWKKIEKTESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1G6</accession>
    <name>A0A9P6N1G6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Coiled-coil and C2 domain-containing protein 1B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">CC2D1B</name>
        <name evidence="5" type="ORF">BGZ80_004295</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CC2D1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000220">
        <property type="protein sequence ID" value="KAG0020389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1G6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001227">
        <property type="term" value="F:DNA-binding transcription repressor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039725">
        <property type="entry name" value="CC2D1A/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006608">
        <property type="entry name" value="CC2D1A/B_DM14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13076">
        <property type="entry name" value="COILED-COIL AND C2 DOMAIN-CONTAINING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13076:SF9">
        <property type="entry name" value="COILED-COIL AND C2 DOMAIN-CONTAINING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00685">
        <property type="entry name" value="DM14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2" evidence="4">
        <location>
            <begin position="530"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="388"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="715"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="851"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="40"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="75"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="114"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="154"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="176"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="186"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="755"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="778"/>
            <end position="806"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0020389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="961" mass="104114" checksum="76FA77704F0E3DC0" modified="2023-09-13" version="1">MFSWKKQNPPSQQRQQRQAHQGTSDYSDLIAHGMRLANEDINDDDMGDINDEDLGDIDLDDPELLAELHGLTGEAPASKPKPAAAPSRPVAKAPAPVQTTKPVAAAPLPPKPAPVAKAPPTKVSGPVQLPNKPSPSTTPAVPPSLAGLGLDLDGVMDDNDDEELELTEDDWKDPHLLAQLQLLGGHTEHHDEEPQKTMGAPTKAVSSPKAEATVSKPLTQTTPIPSESGPLSPASPPSLKEQRRISTSSSMIAIPPKDQAFGDEDIDGDSFMGEQQQEEIRDVDESSAPSPVKAKPQKRAEEIPKKNDKNLLELLKTRDLQYKKAAIEAKKAGNMPLAAERAKVFKGLQPWIRLVEAGGFLDLELYPIPDEPPALAAIVKNDVGVGGATPAAPSTQPKDTEAKTPVHPVMAPTSDTKTQDSIAEASAEDMRSGSNLRGAPGGRFEIKQLAADDDFQIISNSSDDTYDMLQSQLESQINMCQTAYKYYYYQSGDLQTAGKFRSLRKTFIADLESLQSHRSHGKKAPAFHFQDVRFELEVGYYQEIGLNDLSLNIVRAWDLSHKDVQPSDIEAYVLWDLGWPTENMAGTGSGKGSTPTAKRSSKPEFNFTKTLGIQRGMAFQRFAEKKKITFEVWHYRGFLWKDYFIGRAQLPLAALLNHSEIHEIIPLTDASNRRSTGAKIEVQIRLQQPLLRREIVVKEEKWLVIDEFNSGGLGFPTPALTAPGSRPAGGISKARTPAGRATKAVTAPASPATRAPNSPASARSTVPVSKPAPPKQVATSTGTPTTTASPARDNRPAPVTPKASAPAPKPPAPAPAAKIPVPTSATAGDPEESESEKALSELNNVDLLVSNMVLESEIQQAKQMIHDARAVGNSEAAEEYQDRLTQLEIKMKLLVIRVQTGQLTMDAYCQSVNERIAKDRALAIEFKRIGMIPEAKKALARSKIMAQEMKEVEEAMAAQGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1K2</accession>
    <name>A0A9P6N1K2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_001772</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000141">
        <property type="protein sequence ID" value="KAG0021757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1K2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902554">
        <property type="term" value="C:serine/threonine protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043539">
        <property type="term" value="F:protein serine/threonine kinase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006611">
        <property type="term" value="P:protein export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047173">
        <property type="entry name" value="STRAD_A/B-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48014">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE FRAY2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48014:SF21">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE FRAY2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="1122"/>
            <end position="1140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="1146"/>
            <end position="1169"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="50"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="288"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="512"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="608"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="734"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="15"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="295"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="349"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="370"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="516"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="531"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="609"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0021757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1228" mass="133867" checksum="6B97D1404B2372DE" modified="2023-09-13" version="1">MERMASSGSLRRPTSAHTNSSIGPASPIGNLSMSSLVHPEDVFSNNPEDYDIRLPIGYGSSAVVYNAYYKPLNKRIAIKVIDLDMFERNQIDELRRETQVMALCKHPNVLRVNGAFVTDSKLYIVTPYLSAGKDVKAGNLLMDDDGSVLLADFGVSSSLMESGERRGMRKTFVGTPCWMAPEVMEQAEYDYKADIWSFGITAIELATGHAPFSKYPPIKVLMLTLSNDPPTLDRDSTKHRYSKMFKEMIDCCLQKDPTRRPSAEKLLNHPFFKQAKKKSYLVSSLLHNLPPLEQRPPKKAEKKPPLPEKGVSWDFEGDESASAGQSTPPPGNDVSRRPRTVKFEPSPSRPLSTATTGSAENRTIDSLPGDTSSSHDSTTLSIHVGDKPAKKSRFVIEDSVSASSPVISHATEILPSPPQPLPPILSAQVPTHGVIQPGNMQGLGVSHGATDQGVLPEVRKGRFSVKDTSLSVVSPVLPSIKIMPGDALMSPRSLSSSPIEGTSEGVRIVTPLESHPPSERKSRFEVHHSHNTPISDSSTLTTGVGTNPPSQLVIHGAPLSREPSQPRVVSDTGLIRDISTTRVSRFSIEPNITHSESPSTPVSVVISSAGTPTHSSGPLATPNKRSRFQVSSVEGGRPVGDQGEGPGSIHSTPATSPTGSLLRGHPGLLDALGTQSVYSYLDTLYRQNEQQRVILTELFAGFGLKTGSLGKAHNEGGACYSAGSSGTVNRQEQSATFERQLQAAVRENESLRRENEALKRELDRLRRGGMGLKFVSKDRQDRLTAIGRYLADSSRGYDIVGLQEVWVYDDYLRIKELVQDTLPHTKHWHSGILGSGLVILSKYPIVSTTMRRFALNGDPFKFFHGDWYVGKCVVSATLAHPSCGEIEVFNTHLHAGYDPIGTPDSYLGCRVGEAWEMASLIKAATTQGRHVISLGDYNSAPNSLVVQLLTKHGGVTDSWIRVHSEPRDPIPTGLTPEEGVAIMGVTCDTPLNTWTKHTWLNYLTNDPVGERLDYIFYRETPEMVCTSVKVAVQEKISGIGKPNSGPKNYSDHFGVNATFSIKPAVYHFQDRRPGLESLDSSTTMGDTKGHGLSVDKLEEILLLLNHHSAAAKARSKLELTTVFPLMLICALGLIIAFFWISPRWVAFILALVLSALSSGWIVHFLYGFLYGGETASAYINTIQEVQTVLDYKLLGDQNTSRSTATGISRASSSGRYDAQGVRLGLIQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1K6</accession>
    <name>A0A9P6N1K6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004227</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000218">
        <property type="protein sequence ID" value="KAG0020416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1K6"/>
    <dbReference type="OrthoDB" id="2401771at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="511"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="513"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0020416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="581" mass="64549" checksum="AF43BA29AEE39FCA" modified="2023-09-13" version="1">MESLVSEQVNSPPHSQMPQGLVRRCAQNPLDLPEIITRIGQFLPLWSGEGFQREFEPLPLLRCALVSQAFRQALLPTLWYLYDGFRMRNVPHHILIKYSHLFRIISNTGPFKGPFRCKNLIELSTVYGQEWSRDLLVTNPGLKRLVWGGPYYRRIETLEQQQEWQLELTALMGLENLDVLKTSGFSLGEGIFVKVLRNNARLSNLALSTVEGVTSIEGLELPYLTELHIAFGGDESPALVDLVRCCPRLQKLSLTSSRARSSGMTTPHATNNQLSSSSLNITNNEFQIERLAQNIAQCCPELSSIKFTSNHTIGAASWPQIQSFLLDNEFAALVNACHRLESFSAEMITLDYALTEALVSQQRSLTSLSLTVHDSSLGLTVSDRARELHCLRRLKSSLEQLKELTLSWDKGLIALDIATAPADSATTTTSLLDEGIQEELEAFITEPWGCLDLMSLTVSGLVIGVSPSVSPSLSSSVAVVATIPIQVESVQDSLPTNGGSYDYSTFKASWRPQNQQHHSSNNHNHNDNNNSSSSSIVNLNCASQDDNEMTFSPLLPNIVSLRKLRHLCLDQKTFERIPMDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1W9</accession>
    <name>A0A9P6N1W9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GATA-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_003668</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000199">
        <property type="protein sequence ID" value="KAG0020735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1W9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00202">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00619">
        <property type="entry name" value="GATAZNFINGER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00344">
        <property type="entry name" value="GATA_ZN_FINGER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GATA-type" evidence="3">
        <location>
            <begin position="349"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="51"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="166"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="266"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="54"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="73"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="101"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="166"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="186"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="215"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="271"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="281"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="314"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0020735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="426" mass="44394" checksum="83B2E24F1A3C6E30" modified="2023-09-13" version="1">MIAAPLSPVVTPLSPSPSLSLSSPTSSSSVSASLPVLSSINTKDMVASIPTIGTDLSESTERLSPSTQSAGRPASTPTSLSPSPSTITPTIVTIDKGHPIPTSNALSSSLRSRLSTSAPLSSLSSATPTTIISPKPYLSSSHSSIAPLSSMSKADLTHRAAGGNGYSSTYSMSPPNSGDIHVATPKTHSQFSNPSIPISRDGYQSSKDDRQPMLSDEEYEDEYEEGDEYEVVDDEEIESDIDLEDSGSGMEVEPKLHQLGERDAEMADVSAGSSSTQLNAESSSEPSSSIPSRKRMASPTSPSDLASGDRLHSSKTPSPKLTPQQTDSSVSPGSNKNAGSGFKKEHKAGVTATSCANCGTTTTPLWRRASDGQTICNACGTYNECHCIWLSSTIHYIGLGGCIKAGKQNTRSMLFLKMIPGDVSGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N227</accession>
    <name>A0A9P6N227_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003273</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000186">
        <property type="protein sequence ID" value="KAG0020963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N227"/>
    <dbReference type="OrthoDB" id="2443965at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042729">
        <property type="term" value="C:DASH complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072686">
        <property type="term" value="C:mitotic spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008608">
        <property type="term" value="P:attachment of spindle microtubules to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013965">
        <property type="entry name" value="DASH_Dad3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08656">
        <property type="entry name" value="DASH_Dad3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0020963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="187" mass="21718" checksum="DC2B1320AE0CC8F9" modified="2023-09-13" version="1">MNAVDIAQLIDKMRIVERKMGLVYTLFKSSVYAVTQQMQEQEQEEEEEEEEQQEQEMAEQQQQEQFNSLQYHQDQNRRSLQGQGESQTEQDEQQHQQSRLSQHQSYELNNNINNNALRSSQSRSTTPSTRAQTVLRVSNANAAREEFQSGMSNGKSVLSLSRGYGSSRWNQGAIRDSDSQTNRPRYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N336</accession>
    <name>A0A9P6N336_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">2-nitropropane dioxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_009528</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000058">
        <property type="protein sequence ID" value="KAG0023404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N336"/>
    <dbReference type="OrthoDB" id="412383at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018580">
        <property type="term" value="F:nitronate monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04730">
        <property type="entry name" value="NPD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004136">
        <property type="entry name" value="NMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32332">
        <property type="entry name" value="2-NITROPROPANE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32332:SF20">
        <property type="entry name" value="2-NITROPROPANE DIOXYGENASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03060">
        <property type="entry name" value="NMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51412">
        <property type="entry name" value="Inosine monophosphate dehydrogenase (IMPDH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0288">FMN</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0023404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="331" mass="35361" checksum="AF0185B55E52A3B8" modified="2023-09-13" version="1">MVLQTKLTKLVGIKHPVVQGGMQWVGTAELASAVSNAGGLGILTALTQPTPEDLRKEIRRCRTMTNKPFGVNLTLLPAMTPPPYAEYGDVIIQEGIKVVETAGNNPGEHIKKFKAAGIVVIHKCTSIRHALTAQRLGADMLSIDGFECAGHPGEDDVTGLILLPLAAKALNVPFIASGGFGDGTGLAAALALGAEGVNMGTRFLCTQEAPIHNKIKEQMVTATERDTSLIFRTLHNTARVFRNKVAKEVIEIERQPGGAEFSQVAPLVSGQRGKLVYELGDPDQGIWTAGQIVGLIKDIPTCDALLTRMVKEAEDTINKRLSTMIVSEAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4A2</accession>
    <name>A0A9P6N4A2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Mitochondrial import inner membrane translocase subunit TIM22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">TIM22</name>
        <name evidence="10" type="ORF">BGZ80_000902</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the TIM22 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Mitochondrion inner membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the Tim17/Tim22/Tim23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000012">
        <property type="protein sequence ID" value="KAG0024601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N4A2"/>
    <dbReference type="OrthoDB" id="75343at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042721">
        <property type="term" value="C:TIM22 mitochondrial import inner membrane insertion complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030943">
        <property type="term" value="F:mitochondrion targeting sequence binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045039">
        <property type="term" value="P:protein insertion into mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039175">
        <property type="entry name" value="TIM22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14110">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14110:SF0">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02466">
        <property type="entry name" value="Tim17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU367038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0024601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="163" mass="17424" checksum="23A62C00F0DFC142" modified="2023-09-13" version="1">MNMNPMPQQPGQPGGATPDQLAFFNSIFRENCPFKFVFGGVTGFALGGVFGVVMSSFEFSGPQLTPQLQELSTREQMRIMLKDMGNRSYSSAKNFAVVAAIFSSSECFIEGYRAKNDIYNGAAAGCFTGGVLAAKGGVKASAFGCAGFAAFSTAIDYWMRHSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4Z0</accession>
    <name>A0A9P6N4Z0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">6-phosphogluconate dehydrogenase family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_008463</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HIBADH-related family. NP60 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000046">
        <property type="protein sequence ID" value="KAG0023692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N4Z0"/>
    <dbReference type="OrthoDB" id="435038at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029154">
        <property type="entry name" value="HIBADH-like_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015815">
        <property type="entry name" value="HIBADH-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051265">
        <property type="entry name" value="HIBADH-related_NP60_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43580:SF8">
        <property type="entry name" value="6-PHOSPHOGLUCONATE DEHYDROGENASE NADP-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43580">
        <property type="entry name" value="OXIDOREDUCTASE GLYR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14833">
        <property type="entry name" value="NAD_binding_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000103">
        <property type="entry name" value="HIBADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6-phosphogluconate dehydrogenase NADP-binding" evidence="6">
        <location>
            <begin position="13"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="3-hydroxyisobutyrate dehydrogenase-like NAD-binding" evidence="7">
        <location>
            <begin position="184"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="292"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000103-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0023692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="344" mass="38113" checksum="995E7FF2172E0A13" modified="2023-09-13" version="1">MLGHLFHVKQQDRVGWIGLGEMGYNMADNLQRYLASQSLTMTVWNRTPGNALKMQHHGAHIARSIEDLVAQSNIIFTSLADDAAVEEVYEILFDLAGQVEHSIIFVETSTIYPTLATKLKERLAVTPQHTYLQCPVFGRPSLAKAAKLVWVTSGDEKAIKKLCLYFTTMSKTIIHLKTTDVSRASAFKLVGNFFVVGTMELLAEGLTLAEKADVDQESVLKFIEAFFPVPSWTEYSKKMTQAPSSKDGVCTVDIGLKDVKHMRQLAQETGASLPTADVAYNHLLTVKEQGKGDHDWSSIVNSLKTPAPSRRQSEENYTAVCASEDSETNSKSMTDIYPPAYDSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SRG4</accession>
    <name>A0A9P6SRG4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_008141</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004329">
        <property type="protein sequence ID" value="KAF9993446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SRG4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052035">
        <property type="entry name" value="ZnF_BED_domain_contain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46481:SF10">
        <property type="entry name" value="ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46481">
        <property type="entry name" value="ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9993446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="249" mass="27628" checksum="3D850DA6EC166A15" modified="2023-09-13" version="1">MSRVSSHSGRSVASSISFRSSASMSYRRQPVFAVELEQFFKLHLGKLPPVAACDAAANTEQRLTHIKNYHSEMLDQLIEFRICQGEDPLACNVLFQQRSQSTKANPNAMSAEEMDKLALAIAKGIAVDQLPLSIGKSDLVKNLVHFFKPGCPIPSEKAIVEAVLRQYHSLAFDTKQVFRSDVAFGSFTSDTWSSKGNRKFIGLTYHYLQPDFTPRSVSIGFRPLEAPHTGEKLKDTIGKCIIQSIGAKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SRJ7</accession>
    <name>A0A9P6SRJ7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Condensation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008422</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004557">
        <property type="protein sequence ID" value="KAF9992753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SRJ7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensation_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45398">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45398:SF1">
        <property type="entry name" value="ENZYME, PUTATIVE (JCVI)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Condensation" evidence="1">
        <location>
            <begin position="25"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9992753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="204" mass="22289" checksum="1DEC4ECC675BE121" modified="2023-09-13" version="1" fragment="single">MLEDIDTPVLPFGLSDVNHDSLDVTGSLLLSQELNDRLRGHATRTGVSVARICHLTWAVVVASTSGQERVVFGTLISGRRRSETSGSTMGPMINTLPIRVDIMDARVEESLYQVKSDISALMEHKNASLTLAQGCSSVPAGIPLFSSLFNYRHKPAKSSDSSNITHMEILDILERSNYPITMNVDDSGSDLTLTCQAVHQLIHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SRM7</accession>
    <name>A0A9P6SRM7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004252">
        <property type="protein sequence ID" value="KAF9993728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SRM7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="16"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9993728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="146" mass="16292" checksum="BED09735F6D79AA1" modified="2023-09-13" version="1" fragment="single">MESLKRKVIDTDTIESASGSGSSGSSSSAPSKIRKIDDVGAEFKELRRLMELAPDQIGSTTAEFHGHFDKIATYLMNSVAMVVNDKHYYRLVEIEFYLNGGKHPDVFTHSDKDQKTCGEWYFHKMNGSYKGGSYKGLDITFGRHGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SSE2</accession>
    <name>A0A9P6SSE2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_007083</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003569">
        <property type="protein sequence ID" value="KAF9997085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SSE2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="362"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="581"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="9"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="51"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="634"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9997085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="634" mass="70756" checksum="DDB6DADA37FAB46A" modified="2023-09-13" version="1" fragment="single">MKVWDEVAARAARSRTSTPSQDLSSGTIESFFDPRNTHNGSELHHVLAQEPSSPMGSSSSSSSSSSSSSPSSLSLPLSLSTAKGGNGDKGGNGDKGGHEELDDDLVIESKSSDHNAKSKFSSRSPPLFDQATLKDSGLYEDNRIIKLDDSFFATASRTTPRHRDNIHSTAIKSPTSTVTRTATPAYNKHNYFLMDLINAANAATSSGSQASTLSLATTSPTTVDVTQELASTPHELSAAVSFSKPSSHMTRIPDVKVCGFHMHALEWHTMQNLGTQEQITLTERAQCPIFNLSVTRWLKKGANNLQKKPFNSIKCHCGDPMVVAPDMTPVDQGGYDLVCPKTLSAFNDLSDKDNTLRRQKYGNIKGHTKSSPGNEQSKPQDSKRPCSKVIKMCDAMYPPLLEPIHAFIPNDEWLDRCFSPRLTRRSYYIPNHGPQRKNRKQLKPSLINTMTYYPMDYSKFRGAPSRQRKPRSVSFNFKSDIITGCVSPRPTSPSRRHGAKDDLNEWPIPDWVEQSMTISDAILNSDKNSFVNLWGGENISDLDKWRVFELDEDVLSHSIKEALEDAKEYSGQHMKKVMTRLEERKEKEKDIDIQLQKLNLERAKMAQEIKAMDRNSLEMTHKCRVCYERVLTHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SSX2</accession>
    <name>A0A9P6SSX2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MULE transposase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006797</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003376">
        <property type="protein sequence ID" value="KAF9998378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SSX2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018289">
        <property type="entry name" value="MULE_transposase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052579">
        <property type="entry name" value="Zinc_finger_SWIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31569">
        <property type="entry name" value="SWIM-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31569:SF4">
        <property type="entry name" value="SWIM-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10551">
        <property type="entry name" value="MULE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MULE transposase" evidence="1">
        <location>
            <begin position="239"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9998378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="436" mass="50440" checksum="44927FC3C10170DA" modified="2023-09-13" version="1">MSEPRNRSKLFNLREAIVVPTQEFKDEIWPLISNVWTQFARYKSIKGETSIIFACRLAKHRDSSSRQAGISSKKRRLTSVRAPMECKIKIRVVHTDADQMTCIERYDETPDHCHTLEDSDKVKRPQAVRQMMINEARKAYRPPAIVVAVKDLAAGQGLEEVNPHISRKEVSNIQATVRSSELTRLIGNADLEHDIHDALQKLRDMNYQVIRFDTDGDYEGFCFAGTWQLGKLGECGWLTLMDSTHKTNRYDWRLFTLYVRDSYGTWCIGAHFFFSGEDESVVTKGLRTIRQLQPKWEPRYILCDQSAIENRAINNAFPGITRGEQNYDVILCTVHVMRAWMRNIPCHKTRNKMIAAMHKKTKIGCNQLIQEAIRTCPLQTTVNYIKRNYSKNTEKWALHARQHSSLLLQVTTTNPLESFHSELKRIMSKHHGLFGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SSX7</accession>
    <name>A0A9P6SSX7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_006782</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003368">
        <property type="protein sequence ID" value="KAF9998437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SSX7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005178">
        <property type="entry name" value="Ostalpha/TMEM184C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03619">
        <property type="entry name" value="Solute_trans_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="91"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="130"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="139"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAF9998437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="180" mass="19984" checksum="EB2A6728BD612BE2" modified="2023-09-13" version="1" fragment="single">IGISALLICVEMVIFAILHVYSFSYTPYVTGKETPVSKSLRDGFNPMDIVYEIGWACKDIVCILTGKPLPVREGHLSGVVKRANTIRAGNRVAGGRNKEGSSAAATGDKASLDDTSLESGKILQEPLLNHVNGQPQEAYQMSQPPYSSAQQQQWQQQQPQPSHIQPQQYYQQQQQQQRQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6STQ4</accession>
    <name>A0A9P6STQ4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_006197</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003048">
        <property type="protein sequence ID" value="KAG0001331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6STQ4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46689">
        <property type="entry name" value="MEMBRANE PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46689:SF1">
        <property type="entry name" value="PHOD-LIKE PHOSPHATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0001331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="199" mass="23323" checksum="16A4D0E3BB079EF2" modified="2023-09-13" version="1" fragment="single">MDSISDFVSNIGHRISDIVHGEDHDEHTQHLPESQLDPTYNPLLEDDEEVEDAYIEATRQEYSAIKPSAQFKCGPVLRYQDINVDQRRWIGSVLIVSDSRDQPSRLILRDPTKSQLGRVSPRHVDSWQGNHFYRYDIQLTLLHHREKNIEYWFETENGRQVQNPQKWNFFVPALEEGFNWAFYSCNGFTSDVEGELLEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SUF2</accession>
    <name>A0A9P6SUF2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005864</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002890">
        <property type="protein sequence ID" value="KAG0003052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SUF2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="189"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0003052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="271" mass="29036" checksum="715A4039962E9EFF" modified="2023-09-13" version="1">MDHHQHQLAQQQRLAQQQQLVQQQQQYLVQQQQQQQLAQQQIQQQHQTGFHQRSLSQPYAPQSPVSIIASQPYANINPSYQQQPYVPPTSLAYSTSGHTSSLSNASSISTVTNAMEGVGLGLTGVTGVDHGRIVTSAVSSSGIYSVKGDAFGNNDKNQAALFASPLMEPSTLPPPKPHHSVEYLTSKRQRTDSGMLQDQTQYDGSSVVSENSIDPSVGNGNGNGMSMNTNITMSMNNTGHIAGMATTENHFANGNGSAPVVLPGINGKLVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SV26</accession>
    <name>A0A9P6SV26_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">CDP-diacylglycerol-inositol 3-phosphatidyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">PIS1</name>
        <name evidence="9" type="ORF">BGZ80_005209</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002583">
        <property type="protein sequence ID" value="KAG0006610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SV26"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003881">
        <property type="term" value="F:CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006661">
        <property type="term" value="P:phosphatidylinositol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15362:SF4">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--INOSITOL 3-PHOSPHATIDYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15362">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0006610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="126" mass="14203" checksum="F9E0227565940E1A" modified="2023-09-13" version="1" fragment="single">KFGAVLDMVTDRCTTACLLCYLALAYPSYAVVFQFLIALDVSSHYMHMYSNNNVLFGVCFADQLFFVILYLFAFEFQKSDIGIVLYPLAILTGPICFGKQVINCIQFANASKSLAQLDIEERRKAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SVM7</accession>
    <name>A0A9P6SVM7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004924</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002463">
        <property type="protein sequence ID" value="KAG0007223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SVM7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="261"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="348"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="445"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="477"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="599"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="375"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="398"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="455"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="477"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="520"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="599"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="619"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="685"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0007223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="685" mass="75357" checksum="E52C9EB40601D1DE" modified="2023-09-13" version="1" fragment="single">SRGQRASARRFITEVICKADSHLKFRKGNRSKDVSTDLRDVKKYKSKVKTRHSCSLIFNNPRFQKPRSPRNMIPSQGQSANQRSRRTSQRRPMTYPMMSNLNGGHRHFHTSIEAISEGDFDSDMDVLTGEPFHYRSPVTLNAAGSIAGGSGAGVHAEGWSGLPVKVRKSIKKRHHSWQNHSNDFLGGPNELGLNAQRLDRFVHPCGQWRARASEHSINEPHHNSSFAPLFNERSFSTLGPQDSSYRAPAPESLEADLANTTTTDPVVPSTPPTHASSDGNNGSMPNPTSGPCIMNSDGELVSVSAIQSIIGPVSASALGGLQSGYYTIHDHHGTHMCRIYEEDFDHSEHDRDLQNTDNDNDMRYGQPATGSESEQQQQQQQQQQQQQQQPEDQNMGSQQGYQQQQLQQQQHHHAMSRELPALPSVPLANEPLPHQIRRVQSATLTSLRQQHEQQRLQQRQQQQESVSLAQHRTVLLTQQQQQQQRPSLPLQTTTPFSDVGVAMSRSSGQPPSARAGLQRASSYPTASTTSSHAPLFSSTGAIIPWSRINGSSTSSALGPDAAVATSHQTGLVFNGFSHSQDLSQQQQQQQSNVISTNLNGTPVLLSPSTTAETPLGNDATSSRSTTTGTTATRTNTGANPNEAGQSQQGESYWRTRLLGSNSLYVNYEGGTLRPSERWRRGGDEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SVU3</accession>
    <name>A0A9P6SVU3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004575</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002318">
        <property type="protein sequence ID" value="KAG0007515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SVU3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0007515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="73" mass="8194" checksum="90ACDBCB4E60B8F1" modified="2023-09-13" version="1">MGGTADSKKIRKAFEDRDDKSKKSQIECYMDEMFGSGRSADIDPKSKKFIVTKNGVVLPGFQIVYIRGSPWCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SVZ4</accession>
    <name>A0A9P6SVZ4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_004552</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002309">
        <property type="protein sequence ID" value="KAG0007536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SVZ4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0007536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="94" mass="10522" checksum="BCCBFA1346F01520" modified="2023-09-13" version="1">MELVFHPLLLPHLKHTSALLALPPSAILAAASTDKSVWTNKLLQDWDNGWDVNSYGEPLDVNTAWNGKPCVEFSLTKPVAPVTRKYQLLHITYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SX81</accession>
    <name>A0A9P6SX81_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Bromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_002597</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001645">
        <property type="protein sequence ID" value="KAG0009244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SX81"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006337">
        <property type="term" value="P:nucleosome disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045815">
        <property type="term" value="P:transcription initiation-coupled chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001218">
        <property type="entry name" value="AAA family ATPase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000061">
        <property type="entry name" value="ATPase family, AAA domain-containing 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045199">
        <property type="entry name" value="ATAD2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23069">
        <property type="entry name" value="AAA DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23069:SF0">
        <property type="entry name" value="TAT-BINDING HOMOLOG 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 8" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bromo" evidence="10">
        <location>
            <begin position="512"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="461"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="673"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="798"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="821"/>
            <end position="834"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0009244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="931" mass="104541" checksum="58F4D0B844D2F5D4" modified="2023-09-13" version="1">MMPPRGVLFHGPPGTGKTLLARALASSCSTETQKVAFFMRKGADCLSKWVGEAERQLRLLFEEAKAWQPSIIFFDEIDGLCPVRSSKQEQIHASIVSTMLALMDGLDGRGQVIVIGATNRIDAIDPALRRPGRFDREFYFPLPNEAARRAIIDINTCGWVPPLDEGFKNELARMTTRYCGADIKALCTEAALRAIRRRYPQIYESNDKLLIDASTIIVEEVDMLKSAKSLTPASYRVTGATASPLPENVKPLLKDHFDTICGTVDTLFPGTSKRSSKGYDNEDSDVAFQAMGYRSFEKLKTFRPRMIVTGERGMGQRYIGPALLHYLEGCMVQQFDLAALMSESSRTPEAACVQYFIEVKRHAPSIIYIPHIDVWWSVVSDAVKATFSNLLEDLSPDDGILLLATSEVPMSSLPITVKRWFLSSAKGRVELSEPDAMKREHFFKPLFDDLVRPPSEFKVQPPSLKPLEQLKKAPPPQPRVPTAEEKKLLMEHDQYVLRELRITLRNIVDELYKERKFKPFFRPVESEELADYERIVKKPMDLATISEKINDRMYLEVKEFLADIDLIVENTSLYYDIHDPSRVIYRARAFQDVAYSMVGRLDPDLIIETEKTATRFRQEAKAQQKTQGERISRRRLGLEAPAVLDDPEILLRNRSFLAKLNLDSAREDSVEVSIKMEDSQSQNQIQGQEAFDRAPMKPTEVDDDGEDSGTSLSLASSRMTSSVTSLTALGAAADENSSAVSIRSMDLDSVELNNEVVEVVVVDVEGAADMTMQTEDGPDTANTSGSFAVDNSLPLVPTSGAENSFPETNDERNGVTPIEPNESKEIEHQAEPKESSPIVETEEEPGELEIDLGGASQFQVTLIKETEHSSVEELDQLRASLYANIWEHRHEWNKSALLADMIQTVFSITRLHREYRASERKAVESYMESIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXR3</accession>
    <name>A0A9P6SXR3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_001473</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001336">
        <property type="protein sequence ID" value="KAG0010448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXR3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0010448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="109" mass="12150" checksum="9ACB59FE6DAE91C0" modified="2023-09-13" version="1">MSRLALGLSYRDCPGLASKLNPLSLKSLWVMTEAEQLDCEMNQLIYDMNYSSLKEVTLVRTKRSPVTESMESSQANLGVLEYFDGHEKHLKSGNATDVVARVVLIKDGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SY77</accession>
    <name>A0A9P6SY77_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_001620</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the paxM FAD-dependent monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001374">
        <property type="protein sequence ID" value="KAG0010282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SY77"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050562">
        <property type="entry name" value="FAD_mOase_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356:SF2">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356">
        <property type="entry name" value="FAD-DEPENDENT MONOOXYGENASE ASQG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="8"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0010282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="146" mass="16268" checksum="AEC9EC8F1DB02064" modified="2023-09-13" version="1" fragment="single">MSGIPPPNVLIVGGGIGGLFLGILLERQNVPYVIFERTKEPKPLGSAMGLDATIMPVFEQLGLLDELMSISLPCKAIQMLGPEFNIMTAIDFKTYKEVTGYEMAMFPRPKLHAFLESRIPREKIVYSKKVLSLEQNDHGVMLRMSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYG6</accession>
    <name>A0A9P6SYG6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001215</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001274">
        <property type="protein sequence ID" value="KAG0010745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYG6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0010745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="249" mass="28370" checksum="A5ECFC10A3E26021" modified="2023-09-13" version="1">MSPLSWQSSENVPHKGFTSSSKLSMAQPHDERESFTDFQDKMDHDYWKSVSTIRSTYFFDGIGRGGGFLAIPHLASHGNAKTNVICRLLEDWLTKKLVEPTISDSIPVLEDSIESSVLSIERHLKRDAKVWAGISQASIHIRCGHVFMLDTCCDDQTIIHLGADEFYHEYPLFVDVEIKMQGESPQNPRTKPIEVQIAFQNVVDREKSSGEEKPYIHQTFISETTTEVDVYNTNENKSQQHQQQLGRNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYI1</accession>
    <name>A0A9P6SYI1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_000584</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001121">
        <property type="protein sequence ID" value="KAG0011584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYI1"/>
    <dbReference type="OrthoDB" id="2345144at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0011584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="511" mass="58012" checksum="13EA315B8AC9DF9B" modified="2023-09-13" version="1">MVSFFNYPELCHELAANLSRRDVTACLRVNRELYSIFLPYLYQSITISNYTQYFPRLLEELQSTGCEPAKKSQKAPAESITDNVQQTSSIPLTSLRSYGHMVETLTIHFKEDIKFGRSRSYRDGFLDSQVGSPETYPGEEQTEVFVKILQSCPFYKVKTLEIRGRHPKYISRPFLYQCGTAFGRHSAETVLQQTRDRSLARIIMAAAAAVDAGTKLDLTTTSSATNTKEQSRGIRRINVSDSSSFGKHSLQAITDTSLLLTLEELDVQCCGYIRSEEMHFALSKLPNLKVADFRCRDKSLALSPYSGLLPKKLTDEEKLVYRCTSPSLITAAKDRIPTVPPALWACRGSLRSLRIGVTDASLEVANANIEGLNQGYRQWICNAEIYWIKDHPDVEKPYPEQLLWFFDQIAILTQLRELCLVTVKPMFHQTRSLELSLKTGLARWSTLTALECLDVEELDHKIELEDVQWMAGNWPALKMIRGLIHEKDEIPSAAVVWLKRSRPDIKLPVTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SYS9</accession>
    <name>A0A9P6SYS9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="4">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BGZ80_011776</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="4"/>
    <dbReference type="EMBL" id="JAAAID010000990">
        <property type="protein sequence ID" value="KAG0012392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SYS9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140492">
        <property type="term" value="F:metal-dependent deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031647">
        <property type="term" value="P:regulation of protein stability"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02659">
        <property type="entry name" value="peptidase_C19C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.210.10:FF:000011">
        <property type="entry name" value="Ubiquitin carboxyl-terminal hydrolase 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.70.10:FF:000005">
        <property type="entry name" value="Ubiquitin carboxyl-terminal hydrolase 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.210.10">
        <property type="entry name" value="Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002083">
        <property type="entry name" value="MATH/TRAF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008974">
        <property type="entry name" value="TRAF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024729">
        <property type="entry name" value="USP7_ICP0-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029346">
        <property type="entry name" value="USP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF644">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22486">
        <property type="entry name" value="MATH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14533">
        <property type="entry name" value="USP7_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12436">
        <property type="entry name" value="USP7_ICP0_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00061">
        <property type="entry name" value="MATH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49599">
        <property type="entry name" value="TRAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50144">
        <property type="entry name" value="MATH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="6" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="MATH" evidence="10">
        <location>
            <begin position="46"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="USP" evidence="11">
        <location>
            <begin position="202"/>
            <end position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0012392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1113" mass="127162" checksum="C7A9F6183FB80C06" modified="2023-09-13" version="1">MDTRPERLSPVSEKPLVIEEHHSVDDVEWMTKKLIPAMPDLEERACEIFQWDIKDWKSLDRRVTGPEFEIGGYKWRILLFPLGNNVPDQVAVYLDSAEPREGQDPNWHVCAQFALLMSNPNDPTVYTSHNAHHRFTVVEADWGFTRFTEIRKLELPHDHRGLPLIDKGHTVITAYVRVYEDPTGVLWHNFIDYDSKSMTGYVGLKNQGATCYMNSLLQSLFFTNYFRKAVFEIPTADDEPSKSVALALQRVFYQLATNPHSVGTTELTRSFGWNSLESFMQHDVQEFNRVLQDNLEGKMKGTAAEGAIQKLFVGKMKSYIKCINVDYESSRVENFYDIQLNVKGCKTLRDSFADYIAVETLDGENKYHAEGHGLQDAKKGVIFETLPPVLHLQLKRFEYDIERDAMVKINDRHEFPLEIDLADFVADGEEKQKAGPDGLKYTLHGVLVHSGDLHGGHYFALLKPERDGKWFKFDDDRVTMATMKEVLNENYGGGEPMENITGMTLAMRQINRHKRFTNAYMLVYIRNNAMDEVLKPIATSDIPEHLQRRLDDERIALENKRKERDESMLYFNARVISDADFKAHDGFDLFSPLVATAGKTLKVRKQDTFATFREAVAANYGLAEDQIRIWTLVKRQNDTVRTDLPIPDSDLSSPMELIKEKYGTRAQADLKCYIEFLESPGPANGKTPASNELSNGTIMIFAKYYDPYTSKLEGVGKLYVQKSAKVGDIVATLNERKGLPPNTPIKLFEEIKPTMIEPMKMKSSFQQSEIQGGDIIVFQKELTPKELSELSAQNVRATIPQYFEYIYNRIVVNFKPKNDEDATLQTYTIELSKKSTYDQVAMKLAEKLGTDPLHIQFTSASSPNGLPKTTIKRLTNLHLQEMLAPGYIHQGGVGQNVIFYEKLDISIVELESKQLLKVTWLGPTLKDESTHELLLPKTDTMNEVVEALLPKVKLEPNGSQKIRMFSVYNGKFIKEYGRKDPIKTIHESLSIYVEEIPTDIYFAKEDEHIVPCFHFSGDISRLHSIPFKMVIKQGETFRDMKVRFRERFGMNEKDFAKVKFTLFHQGGKFSPLSDDDILSDQDPSTIESIGLDHIDKTGRSNRLGPEKAIFIRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZ74</accession>
    <name>A0A9P6SZ74_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Plasma membrane ATPase</fullName>
            <ecNumber evidence="13">7.1.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">BGZ80_000191</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The plasma membrane ATPase of plants and fungi is a hydrogen ion pump. The proton gradient it generates drives the active transport of nutrients by H(+)-symport. The resulting external acidification and/or internal alkinization may mediate growth responses.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>ATP + H2O + H(+)(in) = ADP + phosphate + 2 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:20852"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cell membrane</location>
            <topology evidence="13">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.1" evidence="13"/>
    <dbReference type="EMBL" id="JAAAID010001032">
        <property type="protein sequence ID" value="KAG0012126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZ74"/>
    <dbReference type="OrthoDB" id="116380at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008553">
        <property type="term" value="F:P-type proton-exporting transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120029">
        <property type="term" value="P:proton export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02076">
        <property type="entry name" value="P-type_ATPase_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000042">
        <property type="entry name" value="Plasma membrane ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000211">
        <property type="entry name" value="Plasma membrane ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
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    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
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        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
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        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
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        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006534">
        <property type="entry name" value="P-type_ATPase_IIIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01647">
        <property type="entry name" value="ATPase-IIIA_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42861">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="13" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 13" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="13" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="96"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="124"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="282"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="314"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="682"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="711"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="745"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="790"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="819"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="848"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="15">
        <location>
            <begin position="47"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU362083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0012126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="954" mass="105004" checksum="04F6997A5E5CAB67" modified="2023-09-13" version="1">MARGYKELREPDADTRPLRDHDSLDQSHATREELNSLSLNLGGKRGEGNNKDDVELEDLLRTNPSTGLTTEQASQRLRTFGPNDLPVVKSNKILKFLSYFVGPIAFLIELACIISIFVKDWFNFAIILGLLFLNAIVGYVEEARAESAVDALRQTLALKTRCWRDGNLQELDTTLLVPGDIIVLRLGDIVPADARLLGIGATGIETESDLLVDQSSLTGESLAARKKKGDDVYSSTVVKQGQQMAIVTKTGGNTYVGIAAHLIANTQDEGHFQKVIGRIGNFLILFTLLLVILIIVFQFITFRNDPIRGQVLKILGPVLILAVAAIPVGLPTVCSVTMAVGARGLASKKVIVKRLAAVEEMSALSVLCSDKTGTLTKNELTFDEPYLCDGYSDEDLLLYSYLASEFGANDPIEMAVRSAAEHQVPLLRNRPATQTHIIPGYEVNDFKPFNPSVKYTQAAVWNTENNTSFLVAKGAPQVMVKLVGGHDPAVKAYISMAKRGLRALGVARTVAGTQDQWQLVGLISLLDPPREDSAETISRCQKMGIDVKMITGDQQIIAKEISRRLGLGRVILDASHIVNPDLPEYEISDRFYKADGFAEVTPEHKFKIVDVLQKRGLLVGMTGDGVNDAPALKKANVGIAVHGCTDAARSAADIVLMAPGLSTIIEGVLASRAIFQRMRSYALYRITSTIHFLIFFFVVVLVYDWSLPAKLLILICILNDAATLVIAVDNAQVSTKPDKWRVGQLIFLSCLLGLLLTGLSFGHFYYFYLVKGYQPYPEAEGDDVDRRLDSIMYLHISSAPHFLIFSTRLTGYFWENIPSLLFIIVIIGTQVVALLMVIFGWLTPAVPVTQALAVFGISFISCVILDVIKVQVFKFWTIGAESPICAPFGPRRRMLKKRRQTSIQQERVWKNIKQIQDLGLKAKVVIALRDADGKIPPPLTAYEDGWGRNSIDSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZI6</accession>
    <name>A0A9P6SZI6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BGZ80_010740</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the pacC/RIM101 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000781">
        <property type="protein sequence ID" value="KAG0013974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000100">
        <property type="entry name" value="Zinc finger 45-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050806">
        <property type="entry name" value="pacC/RIM101"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47257">
        <property type="entry name" value="PH-RESPONSE TRANSCRIPTION FACTOR PACC/RIM101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47257:SF1">
        <property type="entry name" value="PH-RESPONSE TRANSCRIPTION FACTOR PACC_RIM101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="16"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="83"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="96"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="162"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="498"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="554"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="713"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="862"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="930"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="999"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1037"/>
            <end position="1058"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1331"/>
            <end position="1418"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="1162"/>
            <end position="1203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="96"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="107"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="167"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="560"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="730"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="781"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="882"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="933"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1007"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="1356"/>
            <end position="1407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0013974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1456" mass="160541" checksum="742F9E086CCF62D4" modified="2023-09-13" version="1">MENIPSPQSFIFSDDYICQWDSCLKNFDDAEMLYEHVRDDHVGRKAHHNLCLTCRWDKCTVPTFAKRDHITSHLRVHIASKPFACEICKKGFKRPQDLKKHEKTHQDNPASAATINNPNAHLQPGNREQTYQPLTPPSYLDRSPSIASSTISAHSPYNMPMSPASMADSTESWSNPGLASPSHSTNSDLYNSPRVSDLGMDLTNNQDFSRPTIDVSGTYYGVFPPAPSNFEDMISPMSAKRSRDGYDELLSDTLGSFAMEAKKKRMDPSYNEDMMGRLNALSAILEVNPLTPDRLISSLPNVNDWNQFNQLNQFCSTLFEDVSGEVFEPQTFDTLFPDYDQKQTPISTDAGFGVNGFQNYNTAAINPNLGNNNSIGNNLGFSAAPQGESIYSTVIPDDPFVTAPTTQPMAYGTEPMPWDIDATPGVQLPGVVRTAPVKATVQQQVNPFDTRYYTLGSSMSGRVKPEVKVEVKEEVFEPKVVVKTERTYADMSTQTKAKQEKYLSEGGQMMMQRPAEKKKSKSSYEGMDPALLMLSAPSVPDTPLPELATDEIAAEDSENGQENTTVEVTEGADTTVSSNTQPASSSRFGGYVQKGLAKQAAAAAAAAAAATTTSTEPLDPLEAMTRQLAQARLEDAPIKTIRKPSTTKPITDGGMERQIKAAKARAACSEDPVRKQHAEVVLNLLKSIDALMTDHRQKVAMWKEAQAKQQQLGAVPRVGSSTHMYPRTGVNVQNQGQIRTVSSYLPRRTPHQASPLHQEHNRSDPDYSQLRSSLTEEKPSAYSSDSPVLYPTSNLHEASEVPFELSEEERRFIEEDIAKTPVESAYPTVHVIGQDELRSKSQQGLQAVKSGVESLRSVLANNPMEHSRDSTAQGFGQDLGRSESGSSSSIAISSSSGIIETQEISSTSPTRSRSGSWSFLPTSLSGKHLQNLSSSSASSYSNSGSFVSPTSQQLRAGSIKDVAESITDSVAESIKSLSSGLKLGQLAEGFGLNGPVPGVSTRRGTGDQYQQNTGPYLNSMRGQASRSRVWMWNGQDVSGDRGAATPTEMQGSDGESITRMRTDSRRDLIKTGAKTEEAAKETAALLAKVREQEDVAMERARRMPEVEKMAQRYQDSWTEIHDHTARNSEKADSADVILEKVIELCMRHAKSSMQLAEEAKDLKDLDESLDEMVSMSENIQKKLVGLEAMIEKLENEAEVSSLAEWKKTKTAELDKYMESKRKELWDKAELLSTRSEQFQKEEAARKLRLYQNQFETDMERFRRTQEERNQDLWRIAEAEAGIVTMESPLDRIGLSNKADPATGVLSNVSGTNSKIPLTVVDLMAGHPAVLNEQEEEERREKEDLDNFLGPATESDSKEEDEDEDEEEEEEEERDVLGDEDIDEDDDEDSEEDEEDEDEEDDSEDDLDPIAKARKSRAQAAAAAARLNQSKSNTIGSTISAFSALSSHPSTTSLSRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZJ5</accession>
    <name>A0A9P6SZJ5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_010698</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000774">
        <property type="protein sequence ID" value="KAG0014029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZJ5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="315"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="51"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="346"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="368"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="390"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0014029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="417" mass="45813" checksum="624DD7BF9463F1DA" modified="2023-09-13" version="1">MSADFVNEVLFPPSPASSQDQSDSQRHLNPGTQSVSAHGGPNSSPSQVTIPPSQHSSSALSSLPETFKERIAHLLTDQRRFHAPAQVLERVHQFFKGPPQLDPAAFEGSTLDAAISVPFPDIMDTDRWGIPVSLTVGANGAQSSTSPQLAPIQSCFMHVPILPSKRLYETDTEVILLDDIRLAGQLNAKLWEEFSNGNVVEAISIVPTSATWFGKTELADWPCVVMSGLKFEQANGADPSGKKYFEVHSYIAVYLGRDPLRQTQFVQMFQDLGISPAQNPESFLAGGNTHLSNGSGIGGQHHRWIAGFRRLFRTQGTSSSGGAKGSGDKLGNTSRYGPGVPWKPSDDEDSMDPQFDDIYSILPPYKKPRLERVGRPSDMRAAWHHNKRRKTEEDEFSKLKDPDLNSKKWGSDDDMSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T023</accession>
    <name>A0A9P6T023_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Golgi pH regulator B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">GPR89B</name>
        <name evidence="8" type="ORF">BGZ80_010009</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000653">
        <property type="protein sequence ID" value="KAG0015165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T023"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025969">
        <property type="entry name" value="ABA_GPCR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022535">
        <property type="entry name" value="Golgi_pH-regulator_cons_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015672">
        <property type="entry name" value="GPHR/GTG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15948">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR 89-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15948:SF0">
        <property type="entry name" value="GOLGI PH REGULATOR A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12430">
        <property type="entry name" value="ABA_GPCR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12537">
        <property type="entry name" value="GPHR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="145"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="187"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="Golgi pH regulator conserved" evidence="7">
        <location>
            <begin position="2"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="domain" description="Abscisic acid G-protein coupled receptor-like" evidence="6">
        <location>
            <begin position="113"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0015165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="248" mass="28301" checksum="E4F98D8A3642E2ED" modified="2023-09-13" version="1">MSRVGIIGVTISAILSGFGAVNGPYSNLFFFLRQVTNADIKLAEKKCMQTFEMIAEKKKKIVIQETRLKALDTNSRVDLNGLKQEVAALEGISRQLFMDIDDLYAEMLAMALINTLFNRTGSTDPITALISKVVSYTNMTIDVRFWSQQLSFFFVGLMIVLSIRGLLQELSKFFKAFSRHISSSNIILFLAHIMGLYFLSSILTMRQNLPLEYRSIISDSLGSLEFEFYHRWYFHCWTVIAIIIDPDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T092</accession>
    <name>A0A9P6T092_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_010087</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000667">
        <property type="protein sequence ID" value="KAG0015022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T092"/>
    <dbReference type="OrthoDB" id="2399191at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040368445" description="Secreted protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0015022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="398" mass="42448" checksum="B3F992476CE2AB34" modified="2023-09-13" version="1">MVKIASTLIFSLTALLSIVEAATNPGACILTVPRHPLTAKGLAKPYILHKGNCDQTNPDQQVFAEATIFDPHTKKFSVYHPLVINQGTKPAIKPVVPVLPKGAIVGLWFGANSDSVTLVGDIGTCVNGLSSQDIFGQVAFCNAEAFFAAVKAAGKCVKIPPIGTDKAGRPCPTTRFFGIIDQDQSDNVNTVYLQSCNKFAQNTKANCKALKNATKISNGSDNNLVAALLDPHLGCKSFTAPSLMEKGVMLSSMALNELQATLQKAPVALVPANDPMVLSNNQLSLDKVNAYRAGVDQPLITSLKQASPKKYCINFDKIAPKYIKAIKDSIINQPSPSPDVANNLFTFMGQRYFASWTNLGCDVLLKKTSAITVTTNKHGVATAVHFCQSSPIPSASSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0W4</accession>
    <name>A0A9P6T0W4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Sorting nexin-3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">SNX3</name>
        <name evidence="15" type="ORF">BGZ80_009208</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Required for retention of late Golgi membrane proteins. Component of the retrieval machinery that functions by direct interaction with the cytosolic tails of certain TGN membrane proteins during the sorting/budding process at the prevacuolar compartment. Binds phosphatidylinositol 3-phosphate (PtdIns(P3)).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Prevacuolar compartment membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the sorting nexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000530">
        <property type="protein sequence ID" value="KAG0016481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0W4"/>
    <dbReference type="OrthoDB" id="5227681at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031901">
        <property type="term" value="C:early endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030904">
        <property type="term" value="C:retromer complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032266">
        <property type="term" value="F:phosphatidylinositol-3-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032456">
        <property type="term" value="P:endocytic recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034499">
        <property type="term" value="P:late endosome to Golgi transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07295">
        <property type="entry name" value="PX_Grd19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1520.10:FF:000030">
        <property type="entry name" value="Sorting nexin-3, variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042138">
        <property type="entry name" value="PX_Grd19_PX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051074">
        <property type="entry name" value="Sorting_Nexin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45963">
        <property type="entry name" value="RE52028P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45963:SF2">
        <property type="entry name" value="RE52028P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PX" evidence="14">
        <location>
            <begin position="33"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0016481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="156" mass="18387" checksum="5226A23C66A0E5BA" modified="2023-09-13" version="1">MNSPTAHHRAFDEHSRLQSKPQTLDDIYGEPENFLEIEVRNPQNHGVARKMFTDYEIVCRTNIPAFKLKNSSVRRRYSDFEWFRDVLERETSRVNIPPLPGKVFTNRFTDEVIEQRREGLERFLQIVAGHPLLQTGSKVLAAFIQDPSFSKDYYHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1B6</accession>
    <name>A0A9P6T1B6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_009111</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000520">
        <property type="protein sequence ID" value="KAG0016589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1B6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043148">
        <property type="entry name" value="TagF_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41349">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41349:SF1">
        <property type="entry name" value="PROTEIN CBG08683"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="829"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="715"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="715"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="730"/>
            <end position="740"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0016589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="857" mass="96014" checksum="EFF58836D0363567" modified="2023-09-13" version="1">MPFSLRNILIAIRDLDHRLDRYENKDDSIASHTNNISNGNISNGNISNGNINSHGSINGASSYGSTTSLVSIRSSSSLHQTEVKKQHQVVFLLTGSMNPDYGVFGLMQKKILDAVKDLLPERVRAVNVIGHCMYGCASCSGIEHKVPLYFTRYFNKTLPYTAQDILALYAAPRTGVSNSARVVLVAPSCGSTSMLAQKPLIELFYRLEKSGLWRFIWKMHPSSLQLDSYNTEDASGGEQTELESVKFILANFTVTQDEHSCLLPFMEAFDVIITDLHSSVPFIATYFTPKVILSYFNDADYGTPERHQEFMDQLSTFVGPEELEALLDNLPAPKGDPSFFHNQYGHVDGKEDLRFGNLAGWPTEQYEPSQPLHYRKVMAQIVLEWKNIYKTMTKTYPDDIEGANNALGLDAKSELLKGEGDITMPITLPRVLPRDRQAAGIELRIMSFNIWNGGLSGGLPLEQTAKAILASGADVVGLQECSTVIQPSGNRRYMLPELMKYLPGWYYSDQKLRPSNIGLRNPWGVVSKFPIINTTEKGFGVKIQLNNHRHPEIDLSYHVMPENRYQPFEHSHSSSFPLSLLKGGCTGYRAPNTRFMYLFNCHLYYFPYQPFQLLKIPYDGQPFLDTAEEAIQSCIDARGKEMETILSEIRQVAEEEKDVPIFLTGDLNEPSHLDWTPLSVLAGLQPMVVNWPMTEMAYKAGLVDLWRAFRPHLTSPGSSLSSPNNGGSGDQSNNHYNAGNSDKDEVECQVIERPGFTWTVLQREEDPNDHYDRIDYIFGLNRESSPIALKEVAIQMGEELCRSGEKNDKDAVHYIVYKSLNDSLESLRVANATIVVAVGCLVGIAAVLRFMIKPLIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1E5</accession>
    <name>A0A9P6T1E5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">60S ribosomal protein L27</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BGZ80_008172</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000436">
        <property type="protein sequence ID" value="KAG0017550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1E5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06090">
        <property type="entry name" value="KOW_RPL27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.770:FF:000001">
        <property type="entry name" value="60S ribosomal protein L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001141">
        <property type="entry name" value="Ribosomal_eL27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018262">
        <property type="entry name" value="Ribosomal_eL27_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041991">
        <property type="entry name" value="Ribosomal_eL27_KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038655">
        <property type="entry name" value="Ribosomal_eL27_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10497">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01777">
        <property type="entry name" value="Ribosomal_L27e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01107">
        <property type="entry name" value="RIBOSOMAL_L27E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0017550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="149" mass="17170" checksum="95CB0B0CA92D8AE9" modified="2023-09-13" version="1">MMENSQKTGFGTSRMAVTKLAGANYDQNATFFNFLTRFLALETCGTKERGYGHAIVAGVERYPLKITKNMGKKRVAKRSKVKPFIKVVNYNHVMPTRYGLELETLKSVVTLDSFKEPSQREEAKKAIKKLLEERYNSGKNKWFFTKLRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1N8</accession>
    <name>A0A9P6T1N8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Plasma membrane t-SNARE, secretory vesicle fusion</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">SSO2_1</name>
        <name evidence="10" type="ORF">BGZ80_007302</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the syntaxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000371">
        <property type="protein sequence ID" value="KAG0018342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1N8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048278">
        <property type="term" value="P:vesicle docking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006906">
        <property type="term" value="P:vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15849">
        <property type="entry name" value="SNARE_Sso1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00179">
        <property type="entry name" value="SynN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.70:FF:000008">
        <property type="entry name" value="Syntaxin family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010989">
        <property type="entry name" value="SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045242">
        <property type="entry name" value="Syntaxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006011">
        <property type="entry name" value="Syntaxin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957:SF307">
        <property type="entry name" value="PROTEIN SSO1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05739">
        <property type="entry name" value="SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00804">
        <property type="entry name" value="Syntaxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00503">
        <property type="entry name" value="SynN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="344"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="9">
        <location>
            <begin position="270"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="10"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0018342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="368" mass="42064" checksum="E4BF94E58A0D3E84" modified="2023-09-13" version="1">MSGRDRLADFQAQSSSNNNQGYGRQQQQYGGNQYGGNQYNQQNQYGQQNQYGQQYGQQNQYGQQNQFAQQNQYSQQPSQYGGRQQPASPTRIEMTTVQQGNAGGNDMGAFFSEVTSIQEDITKIEQNITKIEELHDISLNGVSNEDQSSRTNRQLEGLTADTTQLSNRTKKRIKDIELANLRLANSPEIQIRRTQAAALKEKFLKTLRRYQSSESEARKKYQGRMERQYKIVKPDATQQEIEQVLESDNQQIFAQSVLQSTRYGDASRALREVQSRHDDIKKIEKTILELHQLFIDMETLVTEQAVVLNVIEENTQQTEVHLEVGNKEVDTAIVNARGARRKKWICLIITLIIIAVIVIVILKQVQKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1P5</accession>
    <name>A0A9P6T1P5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">1-phosphatidylinositol 4-kinase</fullName>
            <ecNumber evidence="2">2.7.1.67</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">LSB6</name>
        <name evidence="13" type="ORF">BGZ80_007048</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.67" evidence="2"/>
    <dbReference type="EMBL" id="JAAAID010000354">
        <property type="protein sequence ID" value="KAG0018540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004430">
        <property type="term" value="F:1-phosphatidylinositol 4-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007032">
        <property type="term" value="P:endosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12087">
        <property type="entry name" value="TM_EGFR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039756">
        <property type="entry name" value="Lsb6/PI4K2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12865:SF1">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 4-KINASE TYPE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12865">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 4-KINASE TYPE-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1215"/>
            <end position="1237"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="12">
        <location>
            <begin position="35"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="189"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="286"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="658"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="747"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="894"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="1368"/>
            <end position="1417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="299"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="327"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="381"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="769"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="829"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="846"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="897"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="1428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0018540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1428" mass="157231" checksum="324BBC0CB5BFE1D5" modified="2023-09-13" version="1" fragment="single">VVTPPPALTPDHGEPMTSERFVSIVDSVKEAIRSGIQPIRIAQGSSGSYFCRNLDGKIVGVFKPKNEEPYGQLNPKWAKWIHRNLFPLIPNLGYISEAATSLVDRRLNLNIVPSTEVVWLSSPAFHYDYLDRRAAQHNKGAKPLPEKVGSFQLFLNGFKDANLFMRDHPWPVETGSSAVDVSGKGKYPTLKKRSSSLPLSDGAECHHDEDEASVSGSSTGSAYGGFTDVPGCGPDKPGFKWTPALQQQFREQFEKLIILDYLIRNTDRGLDNWMIRYCEKEGISIVAGPPSGNQKGNPQQQQQQQQQQQQQQQQQDSTWRNSRVGDLLGLYSSSPRSSTPSLREGTGRNAMLATPPGTPPRSSIPPRASSGADLLQEEPCSETTGNVNGATSGSSNTKDPAVVDPAATMESYYGSTHVHAAAIDNGLAFPFKHPDSWRSYPYGWLFLPRPLISQPFTKATRDHFLPLLSSPAWWRETIADLRRLFSIDSDFDQGMFDKQMAVMKGQGWNIVETLKNLEHGPMDLCRRVALVVWDEEVTLEPGFTSMLRRQESRQSLGGEGGYGATAQTYTTTQPKPMMMDANKTAYSNYGSISSTTNRMSNPKALSTPPTAIGDVLPFLTEDQKNSLKQASFKHVSLNQGSFKQAPSYKQSSLPHLAIDIDNSNNDDDANGQPKHESFRQVVSDGEYDLSDDFDEDDDAFSYDEEYDDFEENSPVMDGLSTAQTQLGLATKDTMISLDMALTNPEAVAQNHRRRRSQSDACGRSRRNRQLSVGSGDVNIQNRPPATESGDSSAAPAITPVSLTTTSNHRRSRTEQDDRTGTVRFDTVSPDKTQSRDNATSGVEYESVSSSPLLLQSPPSKSSSSGDINPFDSSKDNKVVSRELEVVERGRSFFTRGNRVNTSSDNQDNPEGRPKWADRLRRGLSFDGHLLVGGIGQAARRERYLRKQKQRELATAQTPISVSAMAYATIDEKTLYIQGGSTDIDIGPGINQFFALDLTQSSWDISKPPWKVLALGSGTQVAPSDYSYSMTVSKDKQSLVVWGHQTGISVYNITSGSWNTPSSLPSNSTKLVEDLAAFGAVTDPGTGLIYIPSGANFGPRSATLSYCMGGCQASATPRIQTFGNTFQQHPHGVFLQQQGNPQVMWVVIAWFLSLSWTKGTDIKPSLGRESMACTVAGDNFVAWGGDLDYEQPKSLGTPVIYNLKTNQWTTSATTPIGAVIGGTVAGVVVLAAIGFFGYRRYKSKKRQDNSLISTTVAMENIGDPNNIQPVIIVRPDALPPLEQPPANEQVHAPIQLGQPPHAILPSETDKYPKYEVEFVTPNDGNFNEEPLSSIISRNPQDRGEIAPTLPLAARNPHVWQQYDARLDPNAQLEAQIAQIQAQHNFLYQQQEETLRLQQQRLEILRLEQQAQMEMLRQQLIANKKDSNDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T225</accession>
    <name>A0A9P6T225_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Ankyrin repeat domain-containing protein 13C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ANKRD13C</name>
        <name evidence="11" type="ORF">BGZ80_007446</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Acts as a molecular chaperone for G protein-coupled receptors, regulating their biogenesis and exit from the ER.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000381">
        <property type="protein sequence ID" value="KAG0018216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T225"/>
    <dbReference type="OrthoDB" id="341259at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021832">
        <property type="entry name" value="ANKRD13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055285">
        <property type="entry name" value="ANKRD13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12447">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12447:SF25">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 13C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13857">
        <property type="entry name" value="Ank_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11904">
        <property type="entry name" value="ANKRD13_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 8" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="8">
        <location>
            <begin position="71"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="Ankyrin repeat" evidence="10">
        <location>
            <begin position="179"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="domain" description="Ankyrin repeat" evidence="10">
        <location>
            <begin position="569"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="306"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="542"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="37"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="329"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="364"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="550"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF11904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0018216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="663" mass="73387" checksum="A1E69A804BAD5CEB" modified="2023-09-13" version="1">MASITVDPADPLALHKLVFLNKVQTLKMYLAPYKSVEPHAKDDKDKDEQQQQSASDAASTFHPAINALDNHLVTPLHLAVMLNRKEMVLILLNAGANPIARSGSGWTPRQEATSLGNRELIEILTRCQRKEFTGSFKTKAMKLVKQLSEVGEFQSWVPFVSGLCPNDTYHIWKKGNCVRMDTSLVGFENMKWVRGHISIIFRVDPATGPELVIVDRVKKITQRLANSSEDEESMKHEPTDEEIEEEVSTCFNSDITSTNVPTSAIKFQRAKAGLWGYRANKVEKVGEYECAVWKMDGVEFRTRVRTEHLKDPSGKPIQPLNRRKGAQKVGDDEKGNASKEKRITLKQALDDKQGEKRISGTSTPPVSGAGVGSAAWGSPGRRPQPLLATFAEPEPMEESENATPAIGELEQAKQLALEKISNSYGDISANTAIFPKKHVRSTGTISDDAFFEAALQEAEGDMTKENGQVNEVEEDSSDDEYIRVEYRESLPPPSPPTITFDEYFDKSKQGELHLGRPLEQKESRKTFGATLWMYDNNNVASTQAPGTNHSNASSASLASQDSASKVSPPKFPLTIEKILPLLEVVGMDNNRLVGKLKEFLEYQLPPGFPIRANIPVFPSLSADVTFVNYDAQRVIEDSMFEIPSSDEGYEGGFVIRPGGEDDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2F0</accession>
    <name>A0A9P6T2F0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_004554</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000231">
        <property type="protein sequence ID" value="KAG0020237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035673">
        <property type="term" value="F:oligopeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004648">
        <property type="entry name" value="Oligpept_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22601">
        <property type="entry name" value="ISP4 LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1184"/>
            <end position="1204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1343"/>
            <end position="1366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1378"/>
            <end position="1400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1412"/>
            <end position="1432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1444"/>
            <end position="1466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1473"/>
            <end position="1492"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1553"/>
            <end position="1575"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1736"/>
            <end position="1753"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1759"/>
            <end position="1783"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1846"/>
            <end position="1865"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1915"/>
            <end position="1936"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="2103"/>
            <end position="2123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="2135"/>
            <end position="2160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="110"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="556"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="732"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="823"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1050"/>
            <end position="1091"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1632"/>
            <end position="1652"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1970"/>
            <end position="1997"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="2018"/>
            <end position="2065"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="120"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="177"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="568"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="582"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="823"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="835"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="851"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="862"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="893"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="913"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="933"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="2039"/>
            <end position="2052"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="2053"/>
            <end position="2064"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0020237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="2187" mass="234590" checksum="9F63C5910BABB818" modified="2023-09-13" version="1">MPGMSKEFDMNAFGSEAEDVGAPAVETATQQSFALPKITDHVGDTGQIDCVQSTNLFLIPLGNVGDTGSICGQKVQEQQNQSLSNTGTLSLDALQQCNDDNVRQDQSLLTTHRTPGTPATPASNGLATPHSARTSYFPATPASGNTFTTNSTNHSIRTTSTAAFGGGNNDHSHQEETVSNGLKSNEQHNQMSPMSTSPVPEARRQRYNRSEIPPAIVTNPSLAAQRLQNLSTSQGPSIPHTPAIFAARINYPTSASLVTATATATTAATPKTPSSTNEWRMMQMQLQQQDDLHFSLALPSVSSFSASVPNTRVMSAFGQIHVPGSAAPLSASSSTCSCCYNNPSHSPSANASTTPEAIIAGPNFVQSPTSAAPTFGNATPGPDTATQYHSFLLHPNSPANVLAAAAALESYGSSDNQRRSWVGSAVYQHHPNHSGHHLHSNGNLSTTSSDYFSSREQHAQGMPQGHGLRLAQASLASSPASLQYEYTPSSMGSCEYDHPADNSINNNIRSESYGPDSAGSEARLGQFVNYPYLPAPTSAVGGDKVKHCRNCRQNISRRPSMAKGANTADIQTPISTPESTIGRGGGGGGGRGGGRGGGEHDMDVSVSSTSLAGCTHSDSIKRRSSPSPGLLRSLSSRLAANSIRKMSASQKSLFSNSDLSTGGVGCQCCQENASCESFTESRVSESHTGGDCNGCSHHGARGCSGNKSSSICSESDPNACGNKIQRAQSKLRNLRGVTGSKRGRKEKNGKSTSKPYEMEYNFSSQFVRQEFAQYNYERQIEDFQRAARVFKEQKALTTAAAAASLAAEARAAVTAAAAAAAATTTSTSTAAEAAITKEQEEHQESTEKSPAPTSSSVVITSDQEKESLRTEQCHSSDSCDVDSATLKGRRKSVATSARSGTLGSVSSSQRHIGANPNASAKAAAAASGSSKRGYGGNLGGGGFDGSRRGSVHQHGKTDSLYLELGQVGMGMGSDLKLPGLGLGNGFGLDETNFDPCTGEATSIGNNNTSISRDVPGLDVRTAIVPPLTQDIGTGAFDDIIASSPTSLRFPWKPDDANSLKGRPSNVSQDARDGAGIGTKHSKTGSSAQTRRSVHSICSADVVSQQIAARHHQHSRLAATSNVASIHSQSQAAMNSNCETISDGNNRGRGVPRTGAVLENSPIQVVRATVGTVDDPSLPCFTFRMWVLSTIFVVMGAAISEYNFFRSNSAYFSIYFVQLASYFCGKAMAKCLPTREFEICIPGLWWVASKCSKISSFLSLDSGDEVEVGVNSGNNTLSEDGRRIRSNSTEPICGTDRNVLSRPDIASGTAKSTEFSCGAGDERRQFSWKFTLNPGKFNMKEHMLIGIAAAAGCSPAYASNVIAIQSLVFSSPLGSMTGIGLVISSQFIGFSMAWLLFDYVIKPSVMIWPAALWLPRMFMPVLTSMALLCWIKPSSNVLRKLGSGYTGLGIGCISLDWSIVSGVGPLYTPWWAQCNFFIGLIGMLWVITPIVYFSNYWSAMSYPIVSSNLYDNSSQLYDISKIVNRDLSFNVTMYDSYSPVIMTPYFAITYGTSFMAVIATFVHVALFYGSDILLIARTRCSRRMARAKGSLFCQLVSKILRVPSDSPVEQEYVTPTYPTVMMSQGVPTTERGYSFSFSGRRDSESTSSRNGMIDGGVGIGSIGTISDEPSNFNRSSHYRRLSQPQDNFITPLAQVLMAPQPRTTQPTVDDRDQIPTEMFGTEDIHTSLMRAYPEIPGWWFGAMFVICFAIAVLVCDTTDIRLPVYALVLALLLAAVFAIPMAIIQALSSSQIGLNVLSEVVCGYLLPGNQLGNSVFKCYSYMALYQCLNLTQGFKLGHYMKVPPRKIFIAVIYGTLVGAFVNLQVLEWVLLYNRQALFDADPSSGWSFRNLDLFFSASLLWGAISPTRLFSGGSIYFFLPYCFILGVLLPIPFYIMFRHYPPYGTMCKGNSPFPFLPKCTCPASHIAASSEGDATPALPKTRRGSFHDMNESNPLDDTIKEGRSCSSGVFGHCWPFSKSGKRQQHGDLGDKSINLDSMPGSSSRDNNNNGNGSTAQLESEPSVSSPHVYYGNPDSIWEHRLRRFPWHLVNTPLICMGASFVPQAPASFVVSAGIVAFVFAFLVLRYRHEWWRRYTFVLAAALDAGTQICNMAIFVVFSLILKGSVAFPTWYGNDANNPEKCGVGDGYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3F3</accession>
    <name>A0A9P6T3F3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Probable valine--tRNA ligase, cytoplasmic</fullName>
            <ecNumber evidence="4">6.1.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Valine--tRNA ligase, mitochondrial</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Valyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="primary">VAS2_1</name>
        <name evidence="20" type="ORF">BGZ80_000526</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>tRNA(Val) + L-valine + ATP = L-valyl-tRNA(Val) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:10704"/>
            <dbReference type="Rhea" id="RHEA-COMP:9672"/>
            <dbReference type="Rhea" id="RHEA-COMP:9708"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57762"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78537"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.9"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.9" evidence="4"/>
    <dbReference type="EMBL" id="JAAAID010000111">
        <property type="protein sequence ID" value="KAG0022327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3F3"/>
    <dbReference type="OrthoDB" id="629407at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004832">
        <property type="term" value="F:valine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006438">
        <property type="term" value="P:valyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07962">
        <property type="entry name" value="Anticodon_Ia_Val"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00817">
        <property type="entry name" value="ValRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.730.10:FF:000009">
        <property type="entry name" value="Valine--tRNA ligase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000020">
        <property type="entry name" value="Valine--tRNA ligase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000078">
        <property type="entry name" value="Valine--tRNA ligase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.740.10:FF:000005">
        <property type="entry name" value="Valine--tRNA ligase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.380">
        <property type="entry name" value="Valyl-tRNA synthetase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.740.10">
        <property type="entry name" value="Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02004">
        <property type="entry name" value="Val_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033705">
        <property type="entry name" value="Anticodon_Ia_Val"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037118">
        <property type="entry name" value="Val-tRNA_synth_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019499">
        <property type="entry name" value="Val-tRNA_synth_tRNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002303">
        <property type="entry name" value="Valyl-tRNA_ligase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004349">
        <property type="entry name" value="PRK05729.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00422">
        <property type="entry name" value="valS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11946:SF109">
        <property type="entry name" value="VALINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11946">
        <property type="entry name" value="VALYL-TRNA SYNTHETASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10458">
        <property type="entry name" value="Val_tRNA-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00986">
        <property type="entry name" value="TRNASYNTHVAL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="ValRS/IleRS/LeuRS editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class Ia" evidence="17">
        <location>
            <begin position="109"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="domain" description="Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding" evidence="18">
        <location>
            <begin position="778"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="domain" description="Valyl-tRNA synthetase tRNA-binding arm" evidence="19">
        <location>
            <begin position="988"/>
            <end position="1049"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="986"/>
            <end position="1013"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="60"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00040837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00072234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF10458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAG0022327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1057" mass="118773" checksum="D96FCA25B04A359E" modified="2023-09-13" version="1">MADNSASTSASSPATSGTGTPVEKSKNADKNEAKRLAKMEKFLAKQKAAAEKASTPPAGAKEEKKAKPEKAAAATPEPEFVNTTPKGEKKDMSQPMAATYNPKAVEAAWNDWWEKEGFFEPELTADGKIKEEGLFVIAAPPPNITGSLHTGHALAVSIEDGLARWNRMLGKTVLFNPGTDHAGISAQTVVEKQLWKESKQTRHDLGREAFVKKVWDWKDVFQARINNQVRRLGASYDWNREAFTLSESLSKAVTETFCRFHEEGIIYRATRLVNWCSELNTALSNLEVENKELPGRTLLHVPGYDAKERFEFGVLISFAYPVENSDEKIVVATTRIETMIGDTAVAVHPKDERYKHLHGKYVIHPFSGRRIPIVLDDIVVDMAFGTGAVKMTPAHDFNDYEVGKRHNLEFINILNDDGTLNDNCGEFSGMKRFHARVAVLKALKEKGLYVDTVDNAMTVPICTKTGDIIEPLMKPQWWVSCKGMANDALQAVKDGRLVIRPQTSEKEFYRWMENINDWCISRQIWWGHRIPAYFVRLEGEGQDFADGQFWVSGRTEAAARESAEKKFPGKKFTLEQDPDVLDTWFSSGLWPFSIMGWPEETEDFKKFYPTTLLETGWDILFFWVARMVMLGIKLTGKVPFSEVYCHALVRDAQGRKMSKSLGNVIDPIDVIEGISLQALHDKLRVGNLDPREIAKAEQGQKMDFPNGIPECGTDALRFCLGSYSAFGRDINLDILRVDGYRKFCNKLWNATRFALLKFEEGFLPNATAAKTGRESLAERWILNKLNVAAVELNDQLGQRNFMKATDAVYKFWLYELCDVYIEIIKPITDGSDLVARRSAQDTLYTCLEAALRMLHPFMPYLTEELYQRLPRRDGDKIPTIVKSPFPVNNPSYIDEQADADFELVFAVVRSARSLMADYNMTKGGQIYIHGSTEIAKLLLSEEDGIATLAKGSKSCKVVTDIAAIPEGCASQTVQEGCTVYLLVKGMVDVDAEVQKIEKKLAKVQKAKDDLFKKTQDPTYLTKVKLEIREMNAAKLKDYEAEIATLTSGINTFLKLKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3L3</accession>
    <name>A0A9P6T3L3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_000432</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000109">
        <property type="protein sequence ID" value="KAG0022355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3L3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="215"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0022355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="495" mass="55965" checksum="8821D3192DF1E701" modified="2023-09-13" version="1">MRFPLVINPKTASSSNLHPSFPPHLITSLRLDTIDQLSPLFVDIIQNCHRISSLEVLDFGLDVGFLEEALLLCPAHLKRLAVRSDGFVVMESMVEVVLGSNVATQIQTLSLDIGDIGLEETHSLPWSSFRSILDTCTSLSSISLGNVRVMDVPEYLEETNALHATTVTFPNITSLTLRQCDISGIGRVRLLRMFPNLRNLELVCRDAVFDIENTNANNDSNNAAKGSIESNIKSGNSNDGTEPIPGSEAGVEDHLLCVNLRRVSVRCTNTRSQVDQDGLYRFLIHLPSLETLELMGLGTDSRTLLRIAQEWTRRGVRLRHLHLDFSRRKVLDEGLEMVLRQGCCSKLEILDAWCGPSLLFKFWNQETMQSELPFLETLKGFHLRKDYEALDNQHELEHIMNLTLRQMPKLVDLTIAAKLNDYSVFQGMGREPEVPLPPPDTPMTGIDWSRERPFLQTLAIGFSSDFYSNRMSETPRQVGRRFRFLEDFRFVVNVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T3N7</accession>
    <name>A0A9P6T3N7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_002539</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000163">
        <property type="protein sequence ID" value="KAG0021374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T3N7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0021374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="207" mass="23225" checksum="0229A50C5CA6537A" modified="2023-09-13" version="1">MALGAVEVSKVLRNGMYSFDIILSTIPQLPKPPEFPADPSKDYGNMMTLLKDIDTANVCFIVESGNTPSRVPWAHKCILEKYTKLAEIIQAASTTSKGRVNMEESMVSCPSTLVPDLLPAADYFGISDLRVRCEQAVIGSIEESNVMQILFSFGDRYEDIKEATLKYIVRNMALLIHGDKDPFEPYKSHASCNDILVEVMRRRDKRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T452</accession>
    <name>A0A9P6T452_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Nudix (Nucleoside diphosphate linked moiety X)-type motif 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">NUDT1_2</name>
        <name evidence="8" type="ORF">BGZ80_009862</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Nudix hydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000063">
        <property type="protein sequence ID" value="KAG0023292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T452"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008413">
        <property type="term" value="F:8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042262">
        <property type="term" value="P:DNA protection"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43758">
        <property type="entry name" value="7,8-DIHYDRO-8-OXOGUANINE TRIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43758:SF2">
        <property type="entry name" value="OXIDIZED PURINE NUCLEOSIDE TRIPHOSPHATE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="7">
        <location>
            <begin position="81"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="183"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0023292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="368" mass="41881" checksum="81CBEFE2C3C4425C" modified="2023-09-13" version="1">MTEVRNMTIPQESYEKTQEQCIQQANKAESGNSERNDSREDEFNLEFLSIRKIFTLIFIHDIEHNQQLLPGLFFPRYSPPPPIDASTCAPIILKLLLGQKQRGALLGQWNGFGGKVERGLESIAESAARELEEEAFIKAPLFPVGFIQWVVTRSGGNNHDDKTAYPYRDVMIVYKAHTLERTSTTAEPDSISASKSPAETSGRITEFDPSDEMAPAWWDVDCLPWDSMRINHKVWYPFMLADRPYRGVYWYQTERVDIATTNREDGTEKKTNAQRENAQEIWVEDLKKRCVQFGTRPIGGRLSDKSNDEALESFAKQVGVSGTCYSSIIDSVAEEKRQLESEPTPNHDLDEGWLLTAIAKSEQEWMSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T4B0</accession>
    <name>A0A9P6T4B0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">WD40 repeat-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_008684</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000048">
        <property type="protein sequence ID" value="KAG0023646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T4B0"/>
    <dbReference type="OrthoDB" id="1932312at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006594">
        <property type="entry name" value="LisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052234">
        <property type="entry name" value="U5_snRNP_Component"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44006">
        <property type="entry name" value="U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 40 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44006:SF1">
        <property type="entry name" value="U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 40 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50896">
        <property type="entry name" value="LISH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="211"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="407"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0023646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="457" mass="51113" checksum="E62DD0B24B10156A" modified="2023-09-13" version="1">MEYRRLVSEAHLMVQEFLQTQGYKGALEAYEQEAKGVLEDIPKSMPTPKPLLEVLTDKRMAQLHSQLGQLNMPSQAEEQDFATPGDYNSIPSKIHEVIKDIHPVNIIFARTAEVAVEPRLDDLELDPTMTVKKVGALVTAAADRTIKFTLLDGNTYGDEQPGQVFNILQPHEGVALDIDFHPRHPELMLTSAMDKTMVLTNTITGEQHQHFKDHAKFVVRAKFAKNGDIIVTGSHDKTVNIYKVQPGQDVHQLPRYALDKTLNFKGAVEGLCVLPMTSSRTAPTVVIGTRDDNYLHYVDLNNYSTVKYNMNVNNDDWVSFTPMDISVSPHNDGGYLLVSTDSPTGRQILFRTDSALQLFNYYGVPTDGFSTPRHAWDKSGKFFYVTGNDHKIYCFQVGGSQEIMGILEGHTSVIRGLHMDYGRNMLVSCGFDKSVRLWVSSSALTAAEDQSNMILDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T4C8</accession>
    <name>A0A9P6T4C8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_008227</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000044">
        <property type="protein sequence ID" value="KAG0023750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T4C8"/>
    <dbReference type="OrthoDB" id="627829at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050231">
        <property type="entry name" value="Iron_ascorbate_oxido_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47990">
        <property type="entry name" value="2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="3">
        <location>
            <begin position="197"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="320"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="326"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0023750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="380" mass="41968" checksum="812049C6FDCC1860" modified="2023-09-13" version="1">MLPPLEIPTIDISPLLDSSSTVIRRQEVAIALLNAFTTFGVFYITSPTHPVFSTKKKDQILDATTRLFALDNSHKAKIPKIQPGGFTRGYVPIGGESGSTTKELKEGFSYGYEWPPNELEAKAQEDGGLNGLQGPNAWPEQETLNHLDQGQKDAFKETLQEFYLSVCEVAKGLLKGISLALALPEDELSKYCTTSETISFMRLFHYLPYADQQHSSQIGSSAHTDWGFLTLILSPCKTVGLQLFHDNAWQDVPSVENTLVVNGGDYLSLLTGGKLISPLHRVVSNGKEERYSMCCFYYPDYDAKIPLLVQDEARGQAASGSYSLLRDQRSEEDKDVSSKDQNGGGQDARSIATKLLNGEVNFGDYIVSKWTQVFRKGGAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T4K8</accession>
    <name>A0A9P6T4K8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005484</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000027">
        <property type="protein sequence ID" value="KAG0024178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T4K8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0024178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="122" mass="13511" checksum="1C19667ED22C6EA8" modified="2023-09-13" version="1">MMFTIRANRWAVKTLSTVLYTAFHLATYELELRPLILIMIRTPLSKIALPAAKRFISNSTKVNNVVTTAQISHENPMSASSPSSGRAFKAIAYTVLGSTAVVAGLSHLFKDEVVYWTPNVRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T4M8</accession>
    <name>A0A9P6T4M8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transmembrane 9 superfamily member</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_004530</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000023">
        <property type="protein sequence ID" value="KAG0024290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T4M8"/>
    <dbReference type="OrthoDB" id="1666796at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072657">
        <property type="term" value="P:protein localization to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007034">
        <property type="term" value="P:vacuolar transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004240">
        <property type="entry name" value="EMP70"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10766:SF111">
        <property type="entry name" value="TRANSMEMBRANE 9 SUPERFAMILY MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10766">
        <property type="entry name" value="TRANSMEMBRANE 9 SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02990">
        <property type="entry name" value="EMP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040547243" description="Transmembrane 9 superfamily member" evidence="7">
        <location>
            <begin position="26"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="272"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="346"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="370"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="405"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="440"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="495"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="524"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="559"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="595"/>
            <end position="624"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0024290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="634" mass="71189" checksum="14AEB98C7D99CF91" modified="2023-09-13" version="1">MARSSSRRITKLALLGLASVFSAQAFYLPGVAPHEYAAGDNVPLMVNALTPGSDSELKSVIPYDYYDPQFGFCEPQQEKAQAESLGSILFGDRIWNSPYQINMTVTLDCARLCTQTVSKDQAQFINARIRENYAINWLVDGLPAGHVRPGREPDTEVYSIGFPLGQHDGGQAKTTPSLNNHYEIEIDYHHNVQKESLRVVGIVVRPMSIANPVIGQAECGTLDAEQSTAVYLDETKPTQVTYTYSVKWNEVATAWATRWDKYLLVGEPRIHWFSLVNSIIIVLFLTGMVAMILLRALHKDISRYNQLEAQEDIQEDFGWKLVHGDVFRTPAHPMLLSIIVGNGSQMFLMASVTIIFAALGFLSPSNRGSLATVMIVFYMFFGVVAGFVSARMYKMLGGEAWKSNVISTAFLFPSIIFGSFVGLNFFLISANSSGAVPFGTMLGIVALWFLVSTPLSVIGSYLGFQRPRIEHPVRANQIPRQIPDQVFYLRPIPSMLIGGVLPFGAIFIELYFILNSIWFHKIYYVFGFLFLVFGILVLTCAEVTILMCYFHLCAEDYHWWWRAFFTSGASAFYIFAYSVMYYFSTLQIGSFTSMVLYFGWTAIMSLMFFVLSGAIGFFSTFMFVRKIYGSIKID</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T4P7</accession>
    <name>A0A9P6T4P7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003407</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000019">
        <property type="protein sequence ID" value="KAG0024401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T4P7"/>
    <dbReference type="OrthoDB" id="2447551at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="295"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="498"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="241"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="311"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="341"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="376"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0024401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="561" mass="61081" checksum="405774F8CA8E7F80" modified="2023-09-13" version="1">MYMLHSEDLSVAEFAKLAGITILPEEDEDSTSTSGEPSPNHSSVTSQGMTRPGTGSTANTLDSDRHLTCGSMGSSKLLKKASIWDPQFWTSPSQDGASQSVAPSPPPSPLPPSSVSISTPASPPLIPLMAGLEVSNISRQSIRSLDSGSSIMLNSTTPESGGHENAGSSLVTNREGFTSPVVPPRRVGQTPHPSKESIELSRRLSREMSYTSLTAIAIELRGDQDTKQSTEGAKSEYHSVQQGTQQQQQQLRDVEVEVAPPVIRLEPSEPAEQAGKNLQSQRLAYSVAFHALQPARSKPNACRRPCFHPGSSKASRTRSPSPSPLSRQLEMSDSEGFDSPMEEKDGFDFKETPAGSMLVGSAPQKASTHTPAPRNSRFEISHGVEDTDTESDSLGSTSEGYDASLYHHQSQSLPLILSNHPQDVEPQSSSSKPASPRPPNSDPVRKFTPGTKVGRFTLVQETSTKHADVLRAQQEQDQHKRWMYQRRVSMGDMYPSRFYSDDESDHNVESEDLTGTKTHRRYSTASGVSGAAIEQVNPTLGPEENVVIFQRKRVRRLQQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MC57</accession>
    <name>A0A9P6MC57_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_009043</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010005134">
        <property type="protein sequence ID" value="KAF9991558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MC57"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9991558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="151" mass="17572" checksum="7FE5B498AFD960FF" modified="2023-09-13" version="1" fragment="single">NQERVVIYFGGEPAEEKIAMQLQRQQLRNKAQSRTSNALDKLRNRVDSGLGVRKIIFSKVRKYLRECFRLSTTDRDALIAFLKSREWIVVLYETDADLRIAKDCQVNVIVISRDSDMPIHTKVKTLWRPIGHATQGNFLVYKILWELPSII</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MEF0</accession>
    <name>A0A9P6MEF0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13 14">Diphosphomevalonate decarboxylase</fullName>
            <ecNumber evidence="3 13 14">4.1.1.33</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">MVD1</name>
        <name evidence="17" type="ORF">BGZ80_007635</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13 14">
            <text>(R)-5-diphosphomevalonate + ATP = isopentenyl diphosphate + ADP + phosphate + CO2</text>
            <dbReference type="Rhea" id="RHEA:23732"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57557"/>
            <dbReference type="ChEBI" id="CHEBI:128769"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.1.1.33"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 14">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via mevalonate pathway; isopentenyl diphosphate from (R)-mevalonate: step 3/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13 14">Belongs to the diphosphomevalonate decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.33" evidence="3 13 14"/>
    <dbReference type="EMBL" id="JAAAID010003946">
        <property type="protein sequence ID" value="KAF9994985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MEF0"/>
    <dbReference type="OrthoDB" id="10253702at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004163">
        <property type="term" value="F:diphosphomevalonate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019287">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, mevalonate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016126">
        <property type="term" value="P:sterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000018">
        <property type="entry name" value="Diphosphomevalonate decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.890:FF:000005">
        <property type="entry name" value="Diphosphomevalonate decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="entry name" value="GHMP kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005935">
        <property type="entry name" value="Mev_decarb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029765">
        <property type="entry name" value="Mev_diP_decarb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053859">
        <property type="entry name" value="MVD-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041431">
        <property type="entry name" value="Mvd1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01240">
        <property type="entry name" value="mevDPdecarb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10977">
        <property type="entry name" value="DIPHOSPHOMEVALONATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10977:SF3">
        <property type="entry name" value="DIPHOSPHOMEVALONATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18376">
        <property type="entry name" value="MDD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22700">
        <property type="entry name" value="MVD-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015950">
        <property type="entry name" value="Mev_P_decrbx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="GHMP Kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 13 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 14" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="9 13 14" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12 13 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 13 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 14" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="11 14" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="8 14" id="KW-0756">Sterol biosynthesis</keyword>
    <keyword evidence="10 14" id="KW-1207">Sterol metabolism</keyword>
    <feature type="domain" description="Diphosphomevalonate decarboxylase-like N-terminal" evidence="16">
        <location>
            <begin position="10"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="Mvd1 C-terminal" evidence="15">
        <location>
            <begin position="195"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR015950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU363086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF18376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF22700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAF9994985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="397" mass="43451" checksum="5F5681E059414E8A" modified="2023-09-13" version="1">MTVFEATCTAPVNIAVVKYWGKRDTSLILPTNSSLSVTLSQDQLHSKTTIRASADFTSDRLWLNGIEESIEKNKRLVACLRETRALRAQIEEKDASLPKLASLKIHICSENNFPTAAGLASSASGYACLVYTLSQLFQLPLDASDLSIVARQGSGSACRSLFGGFVAWEMGEKADGSDSKAVQIAPETHWPDLQAMICVVSDEKKGTSSTEGMQLTVKTSALLQHRIKEVVPKRMEEMIAAIRNKDFPKFAELTMQDSNQFHAVCLDTYPPIFYMNDISRAIIRIITEYNKDGVKAAYTFDAGPNAVIYAPEKNMAEIYAVLSHFFPGATFDDSLGLLSKTSTLPPLPQNFDTRVSPVFAQGSVKQILHTKADNGPRVLDSAQHGLLNAEGLPKRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MEI2</accession>
    <name>A0A9P6MEI2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glutathione s-transferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_007552</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003892">
        <property type="protein sequence ID" value="KAF9995298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MEI2"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050213">
        <property type="entry name" value="GST_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14497">
        <property type="entry name" value="GST_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="22"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="2">
        <location>
            <begin position="104"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAF9995298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="240" mass="27518" checksum="B3F6860CB5772144" modified="2023-09-13" version="1">MVSNNSKLSTETMSQLAQAKDNQYKLMYFPFHGVVVALRAMFAMSGANYTLIHPEDWDVQKPTTPFGTLPVLYETTATGEILELVELSVLEYYIGQKNGWVGDKLWENNLVKMYHSSSQAVFDKLIKTVARAPKEIYDQMLEIYTTKILPEWAEYRERALKANGSNGHYVGDKLTIADIKTAAIIDSFISLTGDRYITYEKTPAIMAVYNNLEKQPKYTTWKASEAWKAYDEMNKRLFNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MF45</accession>
    <name>A0A9P6MF45_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007294</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003709">
        <property type="protein sequence ID" value="KAF9996268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MF45"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9996268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="76" mass="8225" checksum="1DF761D11284F020" modified="2023-09-13" version="1" fragment="single">MDESIVGNEEEAGVDLEVMNETDESGKDEAAVDIEKPLTRIKSADLMKTGTVVLTNPQKTGLWLSRPSHGISLAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MF97</accession>
    <name>A0A9P6MF97_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_007381</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the XPC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003762">
        <property type="protein sequence ID" value="KAF9995973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MF97"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000111">
        <property type="term" value="C:nucleotide-excision repair factor 2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071942">
        <property type="term" value="C:XPC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.20.110">
        <property type="entry name" value="Rad4, beta-hairpin domain BHD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2460">
        <property type="entry name" value="Rad4, beta-hairpin domain BHD3"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="BHD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004583">
        <property type="entry name" value="DNA_repair_Rad4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018326">
        <property type="entry name" value="Rad4_beta-hairpin_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018328">
        <property type="entry name" value="Rad4_beta-hairpin_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042488">
        <property type="entry name" value="Rad4_BHD3_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12135:SF0">
        <property type="entry name" value="DNA REPAIR PROTEIN COMPLEMENTING XP-C CELLS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12135">
        <property type="entry name" value="DNA REPAIR PROTEIN XP-C / RAD4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10403">
        <property type="entry name" value="BHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10404">
        <property type="entry name" value="BHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10405">
        <property type="entry name" value="BHD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01030">
        <property type="entry name" value="BHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01031">
        <property type="entry name" value="BHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rad4 beta-hairpin" evidence="7">
        <location>
            <begin position="25"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="Rad4 beta-hairpin" evidence="8">
        <location>
            <begin position="78"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="123"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="123"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="135"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="154"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAF9995973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="231" mass="26229" checksum="7CAC0F30AD1BA9D8" modified="2023-09-13" version="1" fragment="single">MSGLSNPYRTAEKDLEEEELLKSEISERMPTKLGDFNNHPLYALERHIKKFEVLHPRIPVLGHVRGEAIYPRSCVKQVRSKENWLKRGRVIKSEEVKPIKWVKSHAATIFQIRLRQQVALSGERRVGSVKETEQRNVSSEGGGNNDNDSSVYQDEAKGADDEEKDKIPLFGEWQTEAYQPPWVVDGKVPRNQYGRQDVFTPEMVPIGGTHLKGRGIGKVARLLGVDYVEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MGQ3</accession>
    <name>A0A9P6MGQ3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Camp independent regulatory protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006640</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003289">
        <property type="protein sequence ID" value="KAF9999079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MGQ3"/>
    <dbReference type="OrthoDB" id="5572844at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018608">
        <property type="entry name" value="Gti1/Pac2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28027:SF1">
        <property type="entry name" value="CAMP INDEPENDENT REGULATORY PROTEIN (AFU_ORTHOLOGUE AFUA_3G09640)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28027">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATOR MIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09729">
        <property type="entry name" value="Gti1_Pac2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="338"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="165"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="250"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9999079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="409" mass="45935" checksum="45E300E58E6ECD7D" modified="2023-09-13" version="1">MDHNSMETYFGLIKTPHDALIIFEACHLGIISRVHRRLSDIERQCVRSGSVYCFDEREAGMRRWTDGKSWSPSRVTGSFLTYRELDESHGNGGKNVYRPDGLLKQSFSITTADNKKLHLISYYTSEDVTSERLFETPSRDPRFAQIVIPKGIYPETSPHADSHSHSASSTNHSSPSPPTRTRHRPHHRAFLHKDDEKAEVMARRPEPSTYNPGHRRNYSGSMSFKDHRYSPIQANFPDSRSRSNSQNVAYPPSLYGSYGPGPEKRHKSTSPSAASSFPTPPFNAYSPSTSWASDDDQPLVSDAATEDRSAYRDDELAPVMIPALREMPLLATGFDHRKAASTSGSRESYSPVPASAASSNHEQDSLSVLANLATDTLLLPKLEPKEMKERVRWVEDDRQLRALSSMLRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MGS4</accession>
    <name>A0A9P6MGS4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Oligopeptide transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BGZ80_006759</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003352">
        <property type="protein sequence ID" value="KAF9998560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MGS4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035673">
        <property type="term" value="F:oligopeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004648">
        <property type="entry name" value="Oligpept_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22601">
        <property type="entry name" value="ISP4 LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAF9998560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="112" mass="12769" checksum="1A86375AB6C8799E" modified="2023-09-13" version="1" fragment="single">MSEQKHELATEKEFVDEKFDIERSSVVLEEEENSPIPEVAAIVPNTDDPSLPTLTFRFWLMATGFSALISFFNQFFWFRENPITIGMTVVQLLAFPIGKFMARILPSGILNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MJJ8</accession>
    <name>A0A9P6MJJ8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_005495</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002703">
        <property type="protein sequence ID" value="KAG0005188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MJJ8"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042144">
        <property type="term" value="P:vacuole fusion, non-autophagic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037470">
        <property type="entry name" value="IVY1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38407">
        <property type="entry name" value="PROTEIN IVY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38407:SF1">
        <property type="entry name" value="PROTEIN IVY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="310"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="645"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="103"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="310"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="337"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="357"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="452"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="468"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0005188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="710" mass="78061" checksum="F05011198F331583" modified="2023-09-13" version="1">MLSTVSLIDPTTLNPSFSGPENSRMGRPAVIITRADQQTSVDQVQLLLTNAKAYRLQMLALSKAAANFGYALEKIAHSKAAVRDSSNSDTLYKQFEIPLLQHLDTHKANIETTESQYERSMREMSQKIKETEATSLQNGRKRQRDLFQFRQALTTLTMQVDELERIKLGYYFSNLESEQANLQLILQKTSTIVRAEVDIYERIANKGLNDAVLEPMTTQGPDPYCTYPTTDEFSPIFSILPATPIIPTSGSGATGTHTPQPDSIMSDFYGYHESNPFSTARNMNNVSARDRHLFGDASSIESREPVIKQTANVTNGPQTTVETVKATKDTPSLTNGSDKEAISDDAHTTKMTKDSENTTTSAEKVDQVDSSQKNGDKDVTELGVKGPEENESSTQQETKKHTQCEVADDAQSPVDTCAVEEGQEGEATNGMDLRTGQQHHRHQAAPSKDQEASSPSEPASSVRSYPLRSRSGSRSNRLSSTPDSPPVRGAVHIPQDSELLNNRDFSFSYEPSELLVRSRHSTHNALQTFAGFGEIEEEGGFGATPPTTQQQINGTLPQIGRSQLHGLRHHSSDSHLSHSSSIRSSIGSFNSLHHRRSTGKMKTDFESSAAMFDSSLDEPFLPSMKHHPGFDDGMPAFFADEVEDDQGLHHTPPRSIRYGSTNGSRRHSGSEELERTFAEVTTSLSVESVIRMADGSSRNVSSTNLNEITA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MJX2</accession>
    <name>A0A9P6MJX2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005371</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002652">
        <property type="protein sequence ID" value="KAG0005930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MJX2"/>
    <dbReference type="OrthoDB" id="2371717at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="151"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="184"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="216"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0005930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="282" mass="31649" checksum="C8D39C6107768A0E" modified="2023-09-13" version="1">MVSVDEVLSIVACILFCVTLAGFGIRFMNSGWGVYSYIMIFIVLRIVGYGIRAYIDSGAIDPSNDSYVNLIITELILLSIGVVFIMKLIVQLYDFILPKLRSQYSQEPDLFERCMVERTRFFLLPLTVLVIVGAVESTPGHSASDMDLGLVLRKVGICLLMLLGIWYFYSTFVYRNRYPANSRAFTIALAVIGLFDISIVYKVVCTFYPAAQNTTVVYFIFSPVLELIALGVLSIDLQSYFLGYPSADDIEIQPVAPNGYYQSQPTGYYDYPQQRATAPGYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MLW4</accession>
    <name>A0A9P6MLW4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NF-kappa-B-activating protein C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_004817</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NKAP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002411">
        <property type="protein sequence ID" value="KAG0007319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MLW4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040466">
        <property type="entry name" value="NKAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009269">
        <property type="entry name" value="NKAP_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13087">
        <property type="entry name" value="NF-KAPPA B ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13087:SF0">
        <property type="entry name" value="NFKB ACTIVATING PROTEIN LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06047">
        <property type="entry name" value="Nkap_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NF-kappa-B-activating protein C-terminal" evidence="3">
        <location>
            <begin position="197"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="27"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="55"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="68"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="142"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0007319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="308" mass="35394" checksum="200511D8C14FDDDA" modified="2023-09-13" version="1">MLHHFSSRREQRIAIKFSIWAPSPTDEELRNRSPSPDREVKRKPAKSKNRKDDSGSESESDDSETERKRRRKHSKSDKHKRSSSSRRHKSSRRKSKRSSRRRHSMTPSDSEDDRRSSRKSKRLDESRSPSRLGHDNGKSSRQEITQGPSSETLGKAVDLDMEYPDDMWVEKKIEVPDDDQEVGPLPLQHNDGKMNERSYGGALLAGEGSAMAAYVQEGKRIPRRGEIGLESDQIENFENAGFVMSGSRHQRMNAVRVRKENQVISAEEKRALMIFNQEEKIKKDNKIINEMREMVASKLRSTGNSSSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MML4</accession>
    <name>A0A9P6MML4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">ATP synthase subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ATP4</name>
        <name evidence="9" type="ORF">BGZ80_004609</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Subunit b, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel. These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. In vivo, can only synthesize ATP although its ATP hydrolase activity can be activated artificially in vitro. Part of the complex F(0) domain. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. In yeast, the dimeric form of ATP synthase consists of 17 polypeptides: alpha, beta, gamma, delta, epsilon, 4 (B), 5 (OSCP), 6 (A), 8, 9 (C), d, E (Tim11), f, g, h, i/j and k.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Mitochondrion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the eukaryotic ATPase B chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002331">
        <property type="protein sequence ID" value="KAG0007487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MML4"/>
    <dbReference type="OrthoDB" id="67388at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.2210:FF:000002">
        <property type="entry name" value="ATP synthase subunit 4 mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.2210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008688">
        <property type="entry name" value="ATP_synth_Bsub_B/MI25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013837">
        <property type="entry name" value="ATP_synth_F0_suB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12733:SF3">
        <property type="entry name" value="ATP SYNTHASE F(0) COMPLEX SUBUNIT B1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12733">
        <property type="entry name" value="MITOCHONDRIAL ATP SYNTHASE B CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05405">
        <property type="entry name" value="Mt_ATP-synt_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161060">
        <property type="entry name" value="ATP synthase B chain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0138">CF(0)</keyword>
    <keyword evidence="3 8" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="5 8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 8" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU368017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0007487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="243" mass="26613" checksum="5464E2D713852BCC" modified="2023-09-13" version="1">MALRLLTKSSSVAAVRPMLAAQRSTASVAIRHMATSTEEKQVSPENKAQSIIDSLPGNSLLSKTAYVTALTGAATYLISKEIYVFNEESLVLFAFAITFGGIAKAAREPFNEWADGHISKIRSVLQKARVDHKAAVEDRIGQVGQMKDVVEVTKALYALSKETAELEAEAFELKQKTALTAEVKSVLDSWVRYETSVREREQSKLAAYLIEKIKADLQDPKLQSKILDESIGHVEKIASSSKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MNS6</accession>
    <name>A0A9P6MNS6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Serine/threonine-protein kinase smu1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">SMU1</name>
        <name evidence="10" type="ORF">BGZ80_003613</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the WD repeat SMU1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001969">
        <property type="protein sequence ID" value="KAG0008289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MNS6"/>
    <dbReference type="OrthoDB" id="538223at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006595">
        <property type="entry name" value="CTLH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006594">
        <property type="entry name" value="LisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045184">
        <property type="entry name" value="SMU1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054532">
        <property type="entry name" value="TPL_SMU1_LisH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22848">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17814">
        <property type="entry name" value="LisH_TPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00668">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00667">
        <property type="entry name" value="LisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50897">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50896">
        <property type="entry name" value="LISH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 8" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="CTLH" evidence="9">
        <location>
            <begin position="46"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="226"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="266"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="309"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="351"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0008289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="553" mass="60796" checksum="76CD2FFE84677D9B" modified="2023-09-13" version="1">MAASNTNTMEIESSDVIRLIQQFLKENNLLNSLAALQEETTVALNTVESVEGFSSEILQGNWDNVLRIVSQLKIPEKKLMDLYEQIVIELVEMREIGTARTLLRQTTPTQLLRDQFPDRYLHLEHVLSRSNFDAKEAYPNGVSKEKRRQIIAQALSSEVTVVAPSRLVTLLGQALKFQELQGMLPPDSAYDLFRGTVPVVQAETDDVPTKCYNTIKFPKKQHAECVAFSPNGQYLVTGSMDGFIEIWNYLTAKLRKDLKYQAEDNLMAMESAVLCLAFSKDSEMLASGAQDGKIKVWKIQTGQCLRRYSPAHQGGVTSVCFSPDGTQVLSASFDLTIRLHGLKSGKMLREFRGHTSFVNHASFSLDGSQVMSSSSDGTVKIWDYKTASCLRSFTPHDGTGTMAGSSGLTVNSCIPFPKPNQILVCMKSPTAYLLTMEGEPIRKFMSPESQTEGATKDLNAAAAARAAGAGDSAKKEGLGVPMTDYMAISLSPQSEIVYCLAENSQVHCFYSDTGKHIKSIPVAEGEVISMVSHPYSNVLAINTVDGRVLLWKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MP15</accession>
    <name>A0A9P6MP15_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Vacuolar protein sorting-associated protein 26B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">VPS26B_1</name>
        <name evidence="4" type="ORF">BGZ80_002816</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VPS26 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001712">
        <property type="protein sequence ID" value="KAG0009029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MP15"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.640:FF:000010">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.640:FF:000001">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 26A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028934">
        <property type="entry name" value="Vps26-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12233">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING 26 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03643">
        <property type="entry name" value="Vps26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0009029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="299" mass="35315" checksum="DC1AA5674A4A3716" modified="2023-09-13" version="1" fragment="single">MSVANLFGFAAPVDIEIVYNGEEERKMVEVKVDKDRREKFPLFFDGETVSGKIQIRVKDGKKIEHNGIKVEFVGNIELFYDRGNHYEFSSLQHDLAVPGELRSNTTYDFEFKNVEKMYESYHGINVKLRYFVRVTILRRLADVVKERDIWVYSYVMPAESANSSIKMEVGIEDCLHIEFEYNRSKYHLKDVIVGKIYFLLVRIKIKHMELSIIRRETTGAAPNQYNESETITKFEIMDGAPVRGETIPIRLFLGGFELTPTFREVNKKFSTRYYLNLVLVDEEHRRYFKQQEITIFRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MP41</accession>
    <name>A0A9P6MP41_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003784</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002017">
        <property type="protein sequence ID" value="KAG0008162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MP41"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="106"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0008162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="365" mass="41290" checksum="F67A8FB3BF8E7E60" modified="2023-09-13" version="1">MLDFSEYALQDLHRHQDFRSTFLCHLNHVSDCRKQNDAEALRLQNTDEFIATCKEKYDHAITSKVPEAVRAGAAELLTGEIDHQVEVAKDDLGHNRLREGTAFPLSTTPPGSPGSSPHSAPIATTSQGYLSIEDLSPISSATDKKQTARRSLQRRYGILQEKWTLDSGSIVENILYEAGKKLSVPHPIQSFIIDMQDSYTKKLFSEKDWAEITSDIPKPTMYGQHASTYLATFDDIKTVENLESILEKRPTCDPECEKDWSIGEAARQWDELSSKYTDEANFKILRQLHDILMSHTMEVGGPSKLRNVLVSGLILGDTASTIDLMDKYEIAYKKSNEEKRQERLQELALEDNNDERWRDLLASSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPB0</accession>
    <name>A0A9P6MPB0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_003175</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001825">
        <property type="protein sequence ID" value="KAG0008679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPB0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058519">
        <property type="entry name" value="DUF8206"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32046">
        <property type="entry name" value="G DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32046:SF11">
        <property type="entry name" value="IMMUNE-ASSOCIATED NUCLEOTIDE-BINDING PROTEIN 10-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26633">
        <property type="entry name" value="DUF8206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G" evidence="2">
        <location>
            <begin position="31"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="DUF8206" evidence="3">
        <location>
            <begin position="326"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="409"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF26633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0008679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="650" mass="74191" checksum="AAC9EAEE406CB702" modified="2023-09-13" version="1">MKHGFKYHGLHDQSVQSIRERTKPGDNEINISLLGETGVGKSTFINAFANYLKYSYLEETEMNEMTTLIHSSFEIAGTKVVVGEDDKNERLTNGDSSTQKCRAYEFPYKDDKMIRFIDTPGIGDTRGVKQDRVNFEGILDFISGYDKINGICILLLPDVSRLTTSFKFYEIDFYQAGATLTPLATYIKELETKSQITIRLEPNTMYYFDNEAFKLYAALKQNIAFDAKTKKLYGDSWVQSVEESRRLINRVMDLKPHRTEETLTLDNARRSIFQLVVPMTKINENIAIELQAIQVLKKLAETHQISAQDLKERLIETYMDLNPINLTHPRTVCTSDGCSTVQGNIVRYNKHCHNHCYIGNVSITVLRHASLRICSKMSFSGICKTCGCKWDKHMHVRIDYEEVKKQKTNATVAEKLQETELKTESMQQEISKADTRVKSLESEKKQIFDGLMTFTGFLLQNSIVQQNSGILDYIDMSIRNQERVAKRTKDNSIVESLRQQRREYVVQKEVFENAKKEGKLRSGVITLEDVIEARDGLCRLENNGQALASVLRWGEENQVLATKRETRLVKPHKSSDYNGGYDTSAAYSSHPSTTDSYLAEGGDASRWGAFKKNVGKHILVPPFSTLFTTRLPRNNEASDERTEGEELWCM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPR7</accession>
    <name>A0A9P6MPR7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HMG box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_002729</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001688">
        <property type="protein sequence ID" value="KAG0009108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPR7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051965">
        <property type="entry name" value="ChromReg_NeuronalGeneExpr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46040">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46040:SF3">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="5">
        <location>
            <begin position="386"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="3">
        <location>
            <begin position="386"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="80"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="150"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="473"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="94"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="154"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0009108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="497" mass="53686" checksum="BC2E8EE6B4F55263" modified="2023-09-13" version="1">MAGSAAPGSNYGYQSIYNPTMNFSHPGSYAVPSPATPPSLPPMHNNNAYAPNGTNFQFSYNGDASPVPATSSGAVAAVPAPLATPTGTQPADIQQSPHAQQLQAHQLTPPQQHPQTPQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSLQRQVHQPINTTQSPYQPSPQAHPGMTNLMHGHTIYPGDNRYDRMQQQRYMDPNMQPMMRNGLRAGDMTWASNGMMPDPLGANHAGGAIRNVAGQQVRPPVKQGLGSLNGMGGMAMNGMNGLGGMGGLGAMSPMSPMSPMGWNGMGGMVGAPTSPYGHNPHAQQALQHQQPFHSHGMAQNPYQQQPHMMHHQPGMPQHMGMHGRPGVMGPIVGGGISKKKMKKPIVPVVKDKNCPKRPRNSYIFFTLMKRDDIKKKHPEFKPTEITKMLGEEWQKLSEAEKESYGSMAENDKKRYQNEMETYDANGGATGAAAAAAAAAAAAVGESGISNGPSGTVAELSSEAWRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MPW6</accession>
    <name>A0A9P6MPW6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_002271</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001556">
        <property type="protein sequence ID" value="KAG0009550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MPW6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46283">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE MARCH5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="78"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="113"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0009550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="154" mass="17464" checksum="204D53D56CB2346A" modified="2023-09-13" version="1">MPWVRMAYNSLWAEMVTRLEMRWRQQQIAGSGVARLGMNASIDNADADPPTAAATTYAANAADEELSFFDRKDLGRTIIGALLMPAISSICGSFLGHFSFVRTRIPDNFHRNILGGCLFVVIKDLAGLVGTYQEMKRRRVRRIREYSEFKDERE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQE3</accession>
    <name>A0A9P6MQE3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transforming acidic coiled-coil-containing protein C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_001983</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TACC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001475">
        <property type="protein sequence ID" value="KAG0009866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQE3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007707">
        <property type="entry name" value="TACC_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05010">
        <property type="entry name" value="TACC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transforming acidic coiled-coil-containing protein C-terminal" evidence="8">
        <location>
            <begin position="1000"/>
            <end position="1183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="244"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="376"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="546"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="631"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="788"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="857"/>
            <end position="943"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="999"/>
            <end position="1072"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="1101"/>
            <end position="1171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="248"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="265"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="301"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="417"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="546"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="571"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="597"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="631"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="799"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="817"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="862"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="896"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="910"/>
            <end position="927"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF05010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0009866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1187" mass="130572" checksum="BFDEC83497AD3E25" modified="2023-09-13" version="1">MAQSQGRMPKVSTQLAAKTSQSTLARARGSSTPLIKKTTYRPTDLQGPFPAEIWLWIIEYLSALDLFSLYNTSATLRVLTVPSLVQVIASKTVRLFFYQEYVCRTGITFVFDHFDFTRDKVVFKPQSTHHTITFQNGITIQRPQLEEISVSSRGSRCQGGQVVCSEEGIYSICKEVERSSAVAGRTSSSSRGGQDASVRNEYHFENRFSMLNYMDRELPPLKRGTYDIEAILAAAENAEFAIPPPPSKSSFNSNPFASSTPSSFRSTFNNSTAPSINNSPYPTTTTTTTIDEFDFPVPPSEKPKRSSTRKKDSIRSTLGKFSAPKKADLEPTIAETNIATLDYHNGGRSNNNDNFGDTTTIAAATKDNNDLSFEDKQAGITSPTIVNTVKPRPQRSTPLNRVASPVAGGSHLDAFANSPSRASSPNNISSNSIGAGNELAVYSTPSSRPTSRPTSRPTSRPHSRVSNGRYHSRQLSSDSLTSFNAMIDNEDMDELSRSGHVSFVVSDPEHKRFLEGEIEDPFSPSMSSNDPDADVYLSNLIQQTSPFGSIKSNSRGQSPAFKSRRQRQAEGDDSFFDSTDDGLSDKEGSRFRRSRSGSRTPSSPLSRISVRQLAMTSAGLPPSLNQVLDQGIQAGTTGPSGTLGSQDQSKTNGGFQEPQLPIPESEGHRLDGKQDPTDVEHVEVDIVVQNVNVNDDSKKNDLQIKNDLIVDYSDLDHEDDIPFNQSGTEVLADEEMNLHESHAQSLSFADWMSSSAEISRLDISPPVGAGHFPLPSISEVITSTPLPTVTAMPGPHGTSLLSSNPGNADVLTSSYTPASPSPEAALAPSMSTPPTALERSMLLEKRSTLMENILAKAKGHSKRDDEASHSSSAEEKKRSIPVSPSGKDAAPDESTEAGTPSHSVSFSIVDDVKVLEKSPEESDKGEGEGAEGALTVPSREKRDFGLVRRPSGVMLSSRIRDSTNLDAPRYSIREMEDMKKNVRMDLRIEITNEIREEYERSAEQEAAIYQSEIEELKASLEKEKREKDGLKSVLDEFESSLADFAVSTATEIQTIKEQNIKLTETKEETEEAFILLKTRYDELRDLNSKHVENEGILRKAIETLKQDYETSESRYENLKSHADMKLLHASQELEQAKIVYDSEIAMLKAQLGRQEMQMRTLEQALEIKTKENQDLILFSEELIAKLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MQX7</accession>
    <name>A0A9P6MQX7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_001347</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001301">
        <property type="protein sequence ID" value="KAG0010604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MQX7"/>
    <dbReference type="OrthoDB" id="10251155at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.600">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053998">
        <property type="entry name" value="ACDH-11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052904">
        <property type="entry name" value="Acyl-CoA_dehydrogenase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041504">
        <property type="entry name" value="AidB_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42707:SF2">
        <property type="entry name" value="ACD11 DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42707">
        <property type="entry name" value="ACYL-COA DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22217">
        <property type="entry name" value="ACDH-11_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18158">
        <property type="entry name" value="AidB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0274">FAD</keyword>
    <keyword evidence="2 4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Adaptive response protein AidB N-terminal" evidence="7">
        <location>
            <begin position="18"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="6">
        <location>
            <begin position="177"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase C-terminal" evidence="5">
        <location>
            <begin position="297"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase 11-like C-terminal" evidence="8">
        <location>
            <begin position="465"/>
            <end position="600"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF18158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF22217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0010604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="626" mass="69704" checksum="89B22F7FEF8066C5" modified="2023-09-13" version="1">MVFATADVGFKQDVPEPQNAFLKDPVMVSVLERLLPSDVLKEITPDLVQICEWAITEGAVLLNRMEEDQPRLRQYDSWCRRVDELLVTEAWNKQKEIAAREGVVAIAYERKYGQYSRIYQMTKLMLWSAGGGLYTCPIAMTDGCARVIELLGTQDMKDQVYSRLTSRDPSKFYTSGQWMTERPGGSDVGRTETQAVWDEEKKAWSISGFKWFSSATDANVTMLLARTHDSNPAAAPGTMKSGSRGLSLYLANVRDDDGKLNGVRIHRLKDKVGTKALPTAELQLDGMIAQQVGATHRGVKSISSILNITRVHCAANCTAVMQRLLLGVKEYARRREVFGALLKDQPLHLATLANMELQYRATCQLTYFCIAILGRVEALESKVPEKESKDSLLLRLLTPILKLWSAKNAFYFSQEAMECYGGQGYMEETGIGHAMRDVLVNTIWEGTSNVLSLDLLRVMTETKGEALQAYSDTVRGIMAPLKEKPEWIASSKSLEECLILIAIRFTSFATPEGRKTLESSARGLSMSIADVIAGALLCQHAAWSEAKAKANPSNSVAATEATVDRISAQRWCEELYRRVDHQIQSLGKDERYEQDKMMLFALADARNAAMNKTGNTSEHGYGEAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MR35</accession>
    <name>A0A9P6MR35_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_002188</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001532">
        <property type="protein sequence ID" value="KAG0009655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MR35"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0009655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="256" mass="28916" checksum="D4668DE4798F3660" modified="2023-09-13" version="1">MMICTVEFTSSMPLVAKELPGSEDAGETFALVSRRQEGRVRPELRRSSKTPMKLIIMWRDTTPSKSGCQASQRGHELHDSARRVMVGTVGWNALATLAVVVRSGKIVVGPHNSLFQPHEASHVWLRKDGGEDLHNNVERHTRSKFDKDLSYKKFATTHPRFLDYCTLPVTLTTLWEFKSNTKGAWPGIKVAAHVFYQLHKHGKILKSDVMNCLQMLRVEKGRTEETTGIVGNLNRLVEIMTVEGAYLFSNRGCWLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRM7</accession>
    <name>A0A9P6MRM7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pre-rrna processing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_001763</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001408">
        <property type="protein sequence ID" value="KAG0010125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRM7"/>
    <dbReference type="OrthoDB" id="10039566at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022185">
        <property type="entry name" value="DUF3712"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046368">
        <property type="entry name" value="Tag1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35895">
        <property type="entry name" value="CHROMOSOME 16, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35895:SF1">
        <property type="entry name" value="LIPID-BINDING SERUM GLYCOPROTEIN C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12505">
        <property type="entry name" value="DUF3712"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="130"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0010125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="929" mass="101053" checksum="5A265C7F283786FB" modified="2023-09-13" version="1">MTFTPRQSQDSLAMPYSDTETDYQDYDNNDGGPLPIEYSQTGSRASSFYSFVSSVHTTSSLRSKKSSRSRKSVKKVVSEFLSSNENDIQLRGYGNRNGSTSDYDEDLYEDYEYDTAVKPYRKPFYRRRRFWCYCAILTVVFLAIFIPLFLIVILPKVAQAIMNGSTMQIAQLNMTNPQENSVQVSVNAAIIGIPTIFAATVEFQEPVQVFWLRGPGDQPRVGQMSLGTINKRAFAKAEFTQATTFGIADSQLFGEFAKIMMASETFVWRITAKINVVVLGRTIKDLTLDKTLNLDGLSNFANLKILSFDIPSDAPNGTGALVSIQVSIPNPSPIGMSLGTMEIDMNLKTAYLGRITARNATLVGGQPTILSLEGTILKQTDPESLLELSNLITNYLTNTPTTAYGQGVSVLPDGVHAVSWITAAIVATKMTIPLLPPTPINVIKQVNVKDLSLLLTPQQPWTPTAASSGIAAAFRLPFNLSLNITNIWDPILTLGYQDIPVADISSAVWDRNSSDMTQNNITFILPSSPMPIRPDAHDQFGKFLIAATQQDSFLVEILGSAQSSAVTSIGQVNITVPFNTSLSLPGVNFSKMVPQLTGIAVTGATVNYLIINATVIIQNPSVFAVEAGPTVLHVNGTTGSMTEYMGDVLIPDLKLVPGSNSLQAQFHFQPNDDVFRNAFLTEYILGSDFDISLYGGADSSSVASIVPLMESLRMSTTLPGMSPVPKLVVGGNGNTTVGEFIGQHQVMLQVQILNPLATTLWVQSLSANVTWKGFPFGTIQLAQTFSINPSGIDTTPLFAIHIPTSYQFWTFMITTFLPQNLGVLTGATVVIDMTASIIVSIGGPVGVGYQSGVNYSQDQVGIFLKIEFNLAGLGIGKRRRKRGILEESYSDLDELGPEPDRRDGDAYLAWLKRAVQLTYPDEAAADGWM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRQ0</accession>
    <name>A0A9P6MRQ0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Mitochondrial carrier</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_001421</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001320">
        <property type="protein sequence ID" value="KAG0010516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRQ0"/>
    <dbReference type="OrthoDB" id="2382881at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050567">
        <property type="entry name" value="Mitochondrial_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624:SF9">
        <property type="entry name" value="CARRIER PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G06390)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624">
        <property type="entry name" value="MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="40"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="209"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0010516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="314" mass="34209" checksum="5F69002F4A56FB1C" modified="2023-09-13" version="1">MVPPLITVSIIKSISFSVYEGSKQQIRSVSDSLQGHTIPSLIGLTFISGSIAGTVVAIMSSPLELVKLQRQLEKLMAMHAQKEAEITSLTGDALLRKGLPEDIKPASMSPTAAVRAERQSHGSISQYGVPPKEEAGASSWKTTKAIVQKKGWTGLYKGVNLHVTRDMLGTGIYFSSYETIKRLMSETIEHVRHHDAPSTSQPSPQFKGPGPMVHFFAGGLCGVFSWLVVFPIDLVKSVVQKEVLVANPKYSGALDCAKDIVRREGVRGLYRGLSVTCYRAMPIHSLNFLVYEAVMDYVKKWSGHGNDVLPAGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MRU5</accession>
    <name>A0A9P6MRU5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_001306</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001296">
        <property type="protein sequence ID" value="KAG0010630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MRU5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0010630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="81" mass="9099" checksum="5782166A2708E22E" modified="2023-09-13" version="1">MAEGGKGGEGGEGARATGTNQNEPTFTPLKEEIIWNVLKASIKGLTENRRDGSNGDDWIDRLGEEEPDKQWKWKTQDFYKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MS65</accession>
    <name>A0A9P6MS65_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BGZ80_000592</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the activator 1 small subunits family. CTF18 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001124">
        <property type="protein sequence ID" value="KAG0011566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MS65"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18140">
        <property type="entry name" value="HLD_clamp_RFC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053016">
        <property type="entry name" value="CTF18-RFC_complex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047854">
        <property type="entry name" value="RFC_lid"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46765">
        <property type="entry name" value="P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46765:SF1">
        <property type="entry name" value="P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0235">DNA replication</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="10">
        <location>
            <begin position="531"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="315"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="15"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="50"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="319"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="332"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00043975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0011566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1143" mass="129773" checksum="9DD155ECD0552F0A" modified="2023-09-13" version="1">MSGNDSRTRSKLLIDSDDDIDDDDDDDDELLVMPAGSQKMELQIDRTFSVPFSLTEELNQPNLDGRSESTPTPQLPDTSAANQKEVQRQHAPALDEDSLFGEDFMAQFGDDGELELETTDNRRPLFPRRITLLEATNGGHESGENEDLGLDRLSISQRHRTKSGAPAVTKKTTSTHTATSSTTIISAIPSRFNMFNRSSIGFVPPMSQESSQFEEELLEMSARQHDAMLDDLILEDELLRNEAEDLDDLLQIQYQEQELQQQQQHRGQTQLGLDGINETNKRKHPVTAASSTSALTTIDDIDQFLEQSYAVNDTSLQRSIEKSKKSRLDHASTGSLNSRGASLPVTPSLQGLSIRPRLPEAPKYDYTLPPVTGSFIKAKSVSGQTFYLPKKVRVDNTKRSFVQQLKENSQNRKPLLSIPIHRMMDELDAEIRVQKQEAINRLEYGDNDEPEIIDDVPKDVIEHLWVDKYRPKKYTDLMGDERVNREVLSWIKEWDQCVFGRKYKKFTSEYKQQQQQQQQQRFKEDPLGRPDRKVLLLTGPPGLGKTTMAHVIAKQAGYNVIEVNASDDRTGASVKGKIEAALEIQSILGSDKPNLLIIDEIDGVSSSGGEQSFIKLLVDMATVEVASKEEKSKSTGKKSKKYIKKPLMRPIICICNDQYAPVLRPLRVIAQIYQFKKPSIRSVVTRLQQICEIEQIRSDTRAFGALYEMTEGDMRSCLNTLQFIKNKSKTGALSATSTSTDRMGDGRWDSHGQGLTLETLNRATVGHKDQNKSLFSVWEELFQAPYARKARSALKVMEEDRDSLTYVSRMASMIQTNGDYEKLMQGCFENFPTMIFHDVAMSKVVECTDWLAFYDQLNSKITSNFEYEVGGYVAYTLVNFHRFFAGSVRQKIEYPRKDYESFVAHKAHESILHGMSLNLPAKSQRHFRKSNFATELLSPFLRILSPYLRPVNKQLIKPDERLVLQRLVDIMIHFQLTFVQEKTEDGQFIYRLEPSIEKLGDFSGIGLKNVLTNRYAVRQLIAQEIEVELVRRAEAVKEAKVGMFFGKGAESKDPTNSLGTSLDTVGSLSMPKNMEQDNFEKEAVDFFGRTIVQTKKGQTDRSLDRSFMVESERQMKKKTRIWYKFNEGFSNAVKAKVFISELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MT08</accession>
    <name>A0A9P6MT08_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_000712</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001154">
        <property type="protein sequence ID" value="KAG0011409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MT08"/>
    <dbReference type="OrthoDB" id="2434602at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="185"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="277"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="324"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="344"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="399"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0011409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="410" mass="45061" checksum="9B45BAE28B14D766" modified="2023-09-13" version="1">MNHLRMGTSHLQSSSNSNKNSAHSSRVYRRMRLGVHGLILIWLCITLAYSTAKVNADEVPPPNGAHEMDDFDSYLEGTTCTVRGGECCSNQSAFECQGWFCIGGTCAALGCEYCSQDPNWFCGYVEGVTRNQGLACKYRATLNQPCSNKTMPCMSDMTCSSVNNTCQFTSERWEEYQEEVKSRRVTMAGMIIVLIAMFMAMRRMLKNEEARRRQIWEPVDSSPEASILRRLAEDTQRRVAGGWVQISGSLVEGGNAASAAVGTAFTRIRNNVRSATGGAIRPEDCDDDTLEMLPNGRRVQTRRELEEDMRNFLLEADDEEEDDGHGWDRSRDEDGLLSDHRNSSRSSGSGVAPSGSNRSNNTISPIGMQDGFPDEPPAYDEIRTNGEGQPSLIAGLNGNGATNSPSPTAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MT97</accession>
    <name>A0A9P6MT97_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PPM-type phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_000064</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001006">
        <property type="protein sequence ID" value="KAG0012293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MT97"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004741">
        <property type="term" value="F:[pyruvate dehydrogenase (acetyl-transferring)]-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832:SF792">
        <property type="entry name" value="GM14286P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="2">
        <location>
            <begin position="125"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="433"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="433"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0012293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="535" mass="59957" checksum="4F8C350DB54A0768" modified="2023-09-13" version="1" fragment="single">MAESEVEDMEETIIIIKETSARGGDVNRIRNDFEDVMGMTKSVPSPRSYFSYPKKPSDSLVPQFSGDVLEGSLSSQSLHSSLKNLKMLTPKQVELRLGQYQKSFKVVDQESKKKSKMSTLDQKLVLGYCTNQIPSNSTIEDDLSQHVVRGENNEIERIFFGVFDGHSGWFCSQKVAQELAPSVAKELDLVRNSRDTKAVIEAIERGFLKLDQRIVHDSVRRVLEHPSKPLACSSLLPAISGSCALLAYIDPRGRDLYVACAGDSRAVMGVREPLEGGGHVWRAVPLSFDQTGMNRWEVKRLKEEHPGEENTVVMRGGVLGGLEPTRAFGVARYKWSREIQEKVFQLFPVYRQPYKNLKTPPYITAKPVVRHQKIRPEDRFLVMATDGLWDKMTSDEVVQLVGDLLDGKTGHDEMVLDREEIQKYKQRRRLAIQASSPPSNALHSGMGEQQEEEELTPLNMAAKGPANQIRKFTYRDQANVSTHLIRNALGGADDDKLAATLSIPSPMSRAYRDDITVTVVFFGQQDTTMALSDAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTQ4</accession>
    <name>A0A9P6MTQ4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Peroxisomal membrane protein PMP27</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">PEX11_2</name>
        <name evidence="6" type="ORF">BGZ80_011116</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Peroxisome membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000854">
        <property type="protein sequence ID" value="KAG0013373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTQ4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016559">
        <property type="term" value="P:peroxisome fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008733">
        <property type="entry name" value="PEX11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12652:SF50">
        <property type="entry name" value="PEROXIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12652">
        <property type="entry name" value="PEROXISOMAL BIOGENESIS FACTOR 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05648">
        <property type="entry name" value="PEX11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="1" id="KW-0962">Peroxisome biogenesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="167"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00046271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0013373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="242" mass="27303" checksum="A22D0748A212E086" modified="2023-09-13" version="1">MSSAVSLPINVQPWLKFTATVVGRDKIYRTVQYFSRFLAWYLFRQGATKETVARFNNLKKTLGLSRKLMRFGKPVEHFENAAKATSLKDEILRFFTIGRQLSYAGYLTFDALIFIDGSGAYKFKNIKKYSEYASRFWMSGIVFGILTGLYKTRQIQIRRHVAARGLAHSVESEKSNARTELKALAKEQQSVNRQLVQDGLDVLLPATALGYLSLDDGALGLIGTITAIMGAQTQWRKVNKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MTV7</accession>
    <name>A0A9P6MTV7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_000044</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001000">
        <property type="protein sequence ID" value="KAG0012335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MTV7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36182">
        <property type="entry name" value="PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G10930)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36182:SF1">
        <property type="entry name" value="PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G10930)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040174269" evidence="1">
        <location>
            <begin position="20"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0012335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="228" mass="25093" checksum="F99AA27D4F74A8E7" modified="2023-09-13" version="1">MKFAAILLVLVSLLASATAHMALLYPTPRGGYGTKQYNGRVHDSKWTQKFPCGGYSQGPITKMKAGKLVYVRFLASTMKAKDIKTQPKPTSKSKQFSQARHGGGTCEFSLSYDGGKSFHLIGRYTKSCPDAYYEWPIKIPKNVPSCTTKGKCLFVWSWTANILAQYYHNCADIHLTGVKNGKKPSKSISIVDFSGHKKGVKAPGDGIKHNSGSGPNKKEIYNNMKGKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MU00</accession>
    <name>A0A9P6MU00_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_011036</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000839">
        <property type="protein sequence ID" value="KAG0013494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="258495at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12885">
        <property type="entry name" value="SPRY_RanBP_like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.920">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001870">
        <property type="entry name" value="B30.2/SPRY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043136">
        <property type="entry name" value="B30.2/SPRY_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000261">
        <property type="entry name" value="EH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044736">
        <property type="entry name" value="Gid1/RanBPM/SPLA_SPRY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003877">
        <property type="entry name" value="SPRY_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050618">
        <property type="entry name" value="Ubq-SigPath_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12864">
        <property type="entry name" value="RAN BINDING PROTEIN 9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12763">
        <property type="entry name" value="EH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00622">
        <property type="entry name" value="SPRY"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00027">
        <property type="entry name" value="EH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00449">
        <property type="entry name" value="SPRY"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50188">
        <property type="entry name" value="B302_SPRY"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50031">
        <property type="entry name" value="EH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EH" evidence="2">
        <location>
            <begin position="734"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="domain" description="B30.2/SPRY" evidence="3">
        <location>
            <begin position="1074"/>
            <end position="1265"/>
        </location>
    </feature>
    <feature type="domain" description="B30.2/SPRY" evidence="3">
        <location>
            <begin position="1268"/>
            <end position="1467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="407"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="505"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="592"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="654"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="929"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1381"/>
            <end position="1402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="134"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="416"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="553"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="570"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="620"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="654"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="681"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1381"/>
            <end position="1395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0013494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1518" mass="164700" checksum="4EEE28AE0FEE01D5" modified="2023-09-13" version="1">MYHQSGHPYAHPQPTPPLHQQHQQQPPPPPYPWPPYPQAPVGAPTQQPPSPLYQAYPYYPRPSSSHFDGGHPPTSYPPAGVPTTPLSPSIATPVSIPPASSFDNNALYKAEMSESQIQNWQYSRQQQNIKVEVPSSAVQPTPPSSSSSSGYNKQLQPQLQRQGQLPALQSRQSGAFGGALPSPQPFWNQSSGTNGMSPISAPGPYPSFVASPTNTNIPFGPTPVEHQSSLTESAGSIQSSVQESSLTTLDPAPSASTGINARISRPYSSSQYQPEPQVHHGPSAIEEQSSLTEIGAAAGSTQVNFGITTSGQVGSSCSTSFQNLGHRHNNQSLNASSIEEQSSLTEVDNMPFPIEAQSSLTELDNAPYTLEEQSALTELDDMPHPLENQSALTTLDDLPHGLKEQSALTEIDNLPNRLSDQSSLTTLDEPKSSPSNSVKAKDSTTPPPTRALSTTDATLVTFSATNIATEETISVSTAISPDMRAFADTTASTFSMSNWTLPTDFMNPSVPQADAAREVSEMATESSSETGSLHRRSPTTKQTGADLEEAGPRPTPPKPAPKPASLTAARQSNPQTGLSGTQLTISEEVYLGQIPTPPTDDRVVLVPFQDGSLHDNDREDIGEDEDEDEEDDELDISPLDNVSDFIRALQSDLSKSLSRSGSGSSSLQESTRFNEVKRTDSSSSRVSGSGKVYETPLDQPRVEEVVIEQQDDLQNGELQQLEATQFEWTFTESEQTTYERIFSLWERPAEECVTSDIAGKVFMTLGLRNQDLPKVWQLLNPEEKPVLSRTQFIAGLHLVNCKAIGYELPEDLPDELMISAASVGRVTIPPRPVQGPSSFLPNHVEPATTMNPPSEQPIPSTITQAQNLTPNPSAGSDFMDAYNIPNSTYKAVTLSPVATNLAQRPGDMDFYAGNLQQEQQYQLQQQYSLPDPAPNQFLQQYSLPDPVPNQFLQQYSLPDPAPSQFSQQYQPSMLGLVDDRSIVSPPSPSPRPANSSSKPPSPEKVITPSKPGPHALHDLPEGAPVFVNDEDSLILQMRDIQNSNQSPSAYVTSDSVRASSDLASDASSATVVTSSVINSRHHIDNPELYASAPDAWDHDGAPPELDVEGNNIRYRTDFKNDMMVSASVTANHPINPKSKVFYFEITIDQFKEVKGSAISVGIASKSLRKNCQVGWDLDSWGYHSDDGFLYFGNGKQNIKYAYEYKENDVVGCGVNFLDRAVFFTLNGDMLGVAFRFIKDTIPLYPAIGLSHAGTEINANFGDQTFLFNILDYKKRVMSKPIQSPLLITWNNGSKNEKVFQVLPDCLSVIANGKDAGCIRGPKVSPRDKDVFYFEITILYMPATENGTIMVGICGKDQDMKDCLGWRSNSYGYSSESGDFFSRSSNRSSLNAPSQSGKMRARARGPPFRAGSVVGCGVDFASRELFFTLNGECLGQAFYEVDVLDCFPCVSVVDGGGGVGGPLTQLREQPGPKDSSAARLTKASSSEASDDRIGFEFKANFGQYPFMFDLPGFEASGGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MU02</accession>
    <name>A0A9P6MU02_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Rho GTPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">RHO2</name>
        <name evidence="10" type="ORF">BGZ80_000048</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the small GTPase superfamily. Rho family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001001">
        <property type="protein sequence ID" value="KAG0012328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MU02"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000983">
        <property type="entry name" value="Rho family GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003578">
        <property type="entry name" value="Small_GTPase_Rho"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24072">
        <property type="entry name" value="RHO FAMILY GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0488">Methylation</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0636">Prenylation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0012328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="202" mass="22072" checksum="FE390BC79FE57CEE" modified="2023-09-13" version="1">MAMSNTRDKDIVRRKLVIVGDGACGKTSLLSVFTLGYFPKNPTVFENFVTDVKIDGKPVQLALWDTAGQEAYEVEPMRLRPLSYTKAHVILIGYSVDTPDSLDNVTSKWIQEVHVHCPDTPVILVGMKKDLRDGQESSEQPKTTRFVTTAEAERVAAEIGARNHLECSALTGDGVDDVFEAATRGALTQGNQSQESGCCVIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MU15</accession>
    <name>A0A9P6MU15_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_011132</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000858">
        <property type="protein sequence ID" value="KAG0013351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MU15"/>
    <dbReference type="OrthoDB" id="10496605at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0013351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="169" mass="18905" checksum="A49FEB1205A5EF28" modified="2023-09-13" version="1">MTATECHQDLLSRPQEHQTPSFEDSATTDFSQTGNMSTNPAHQSQSNDESDQQDGSGSQVGSNGTQDGSERHASVTAEPESEKTVLQSLRAPVPEQQILIDSYSYHTTLILRLTPANSNNLNKNDSSPNKNNRNGERKHYHFFLLKEHLKNNSPQHQQPGQQQQPEQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MU72</accession>
    <name>A0A9P6MU72_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Endoplasmic reticulum-based factor for assembly of v-atpase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_011212</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000875">
        <property type="protein sequence ID" value="KAG0013230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MU72"/>
    <dbReference type="OrthoDB" id="19981at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070072">
        <property type="term" value="P:vacuolar proton-transporting V-type ATPase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021013">
        <property type="entry name" value="ATPase_Vma12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31394">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 199"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31394:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 199"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11712">
        <property type="entry name" value="Vma12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="169"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="197"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0013230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="257" mass="28558" checksum="80E29733F6214D3B" modified="2023-09-13" version="1">MVNLQWTPRLEKAFKKLQTKSQSSSVALSLNPVETRTLKEVESILEKPNGPECVDVDLIKRVSALLLKYSTSASDSGGDELSKESIDSNDMSEDWVHVMVKGSSVYVPKPAPKERSPELDRIMEGIKAQIAEKEYQRMISSIDPSANGNLIASGIKQDLKEMKDIKAHMIGIVNVLYTGAAVFTAVFMISAHFTDDLGMRVLLAFLAFVFIVSCEAYLYSRHTSEVTAAPRKKKEIMPKLPDDVVVTTKSFIKEKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MU91</accession>
    <name>A0A9P6MU91_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Nuclear cap-binding protein subunit 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">20 kDa nuclear cap-binding protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">CBC2</name>
        <name evidence="11" type="ORF">BGZ80_011565</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the RRM NCBP2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000946">
        <property type="protein sequence ID" value="KAG0012705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MU91"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005846">
        <property type="term" value="C:nuclear cap binding complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000339">
        <property type="term" value="F:RNA cap binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12240">
        <property type="entry name" value="RRM_NCBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000399">
        <property type="entry name" value="Nuclear cap-binding protein subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027157">
        <property type="entry name" value="NCBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034148">
        <property type="entry name" value="NCBP2_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18847">
        <property type="entry name" value="20 KD NUCLEAR CAP BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18847:SF0">
        <property type="entry name" value="NUCLEAR CAP-BINDING PROTEIN SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5 8" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7 8" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="10">
        <location>
            <begin position="34"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="147"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="148"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="175"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0012705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="217" mass="25018" checksum="FF1178F3E93CC5EA" modified="2023-09-13" version="1">MASIVQSLSVPSTYKDQQYQGTSNQLAQDLANSTTLYVGNLSFYTTEEQIYELFSKCGEIKRIIMGLDRNQKTPCGFCFVEYYHHSDALDCMKYINSSKLDERIVRSDLDHGYREGRQFGRGRSGGQVRDEYRLEFDAGRGGWGHVRARQEAERERDQKANYEAITSIPEGADIGYKDRKEDSSSKRARDDDEDDDEQQRSKTNPRFREGDEDEEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUM7</accession>
    <name>A0A9P6MUM7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Galactose oxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_010669</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000769">
        <property type="protein sequence ID" value="KAG0014066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUM7"/>
    <dbReference type="OrthoDB" id="10251809at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12087">
        <property type="entry name" value="TM_EGFR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23244">
        <property type="entry name" value="KELCH REPEAT DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00612">
        <property type="entry name" value="Kelch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="351"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="379"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="521"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="583"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="531"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="594"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="612"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="633"/>
            <end position="643"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0014066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="651" mass="70148" checksum="1B45825640A33804" modified="2023-09-13" version="1">MAFTKVDTKFFIQGGFSNGNFTSQFVDLELSASWTTSSPIWDTLPTGGPLVSHHTMVYVAPEHAAALGTGKKGYLLTIGGSAPPTLPSFWNTYDLDSGTWAARNFSTPYQALEGHTAVSSPTTGLVYIIGGFWNVTNTVPVAPAVNNSITIFNPVTGTIVHQSLASPQESLTDASAVWSNVTNTILVFGGSRAASNLLSLSGLDMANVIEYDPVSFSSTRRSTTGNIPTRVLDHCTAISDDGSMVVVFGGSTDSKTTSDDLFVLNLGNNTWKQGASASMRRTRMSCGFHSNQFFAWGGSSDQNSNTMHDVVPIVYDIAHNAWTDRYYADGPPSSNPSGQDNPDAPDKKTSLAAIIGGAVGAAVLIGCIAAFILYRRKRRDQKNKAEDDDDNRINRHARAHEARRQRYSAVGAIDDSDIDGSNYINERPLSNIPSLDHYATAAALQRPYHGGNVQSGYWDNLGNYQGPDAQMRPLSGTNVALAENMYDDPLSAAGVYGGPIPASPPPMQWQQQSHVIPQHNYGIPQQSQDFPLQSQGIPQQSQIIPQQIQGLQQSSLQQQQWGNYAPASYYYGSSAEDPRISMVSQGHAPHAQITGASPQSSTGGYVDHNSVRDSNSNFSDTKTNSSTRNPQSITPKTPITNNYIPPPPHHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MUS9</accession>
    <name>A0A9P6MUS9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_010473</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000731">
        <property type="protein sequence ID" value="KAG0014390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MUS9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="2">
        <location>
            <begin position="180"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="267"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0014390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="431" mass="48521" checksum="54E84DDDD048B24F" modified="2023-09-13" version="1">MGHTSVQHYGSTLAFSIVRSDFLNMNSTLPTQTIVRTFNKFSANLSQCGSWRCVFEESKKQHQQSIELQLSLNWVPCSSPLTGGGYQGQEGQDTARELISRIRSVKIRSDSTLSELLVARLDGRCLLPDRVLKNGRYRFRIGFFTKVIPNSSPLERPLSTNFLDIDAEFSPVRCRPNELPDVTFQFPTSDPLGAASIIMAHSSAIKKSRYFAHRVAEVVEEKKRRGIPFSGITCEITEFTPAVFRVMLQFLYTGKLRIKSISGGREEKASAGHSSQAKKGPPKKRAFLNKDPRLGGCIRLPEKVYFEDLYRIAERYEIPPLSALSLKGMQCDLNMSIAIAMLVKLPRESVDVLGASCSQVQDYEEFKGEIRLNKIQVQLVKSIIKEYIQFYAVEAAMLRRPHGEALSVQESLTVIHHIGDCVLDSVEHIWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MW20</accession>
    <name>A0A9P6MW20_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_009570</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000586">
        <property type="protein sequence ID" value="KAG0015882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MW20"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050562">
        <property type="entry name" value="FAD_mOase_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356:SF2">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47356">
        <property type="entry name" value="FAD-DEPENDENT MONOOXYGENASE ASQG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0015882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="454" mass="50845" checksum="65B40927428C860C" modified="2023-09-13" version="1">MLGAILEATNIPYHILERATEFRPLGSIISLTGDILLVFKQLGIYDELKKVSLPTVAMDMFDTELNASGSLPAKHLKIACGDDPLVHTRPKLSNLLRQKVPAHKISMGKKVLCAKEYDNKVTVYCSDNTIYECSILVGADGAYSAVRQNMHKELEEKGNLPLGDKDAFSIGYINMVGISTPSSPEKYPELGDKTRSHSRLVMGDNDDSCYVASVSDNQFCWAIRIQLSEDKAKELHFRNSEWGPESVEPMLKKYRDFSCAFGGTMKEIFDSTPKNLISKVFLEEKVFRTWYHGRSVLIGDGAAMAMKVAVVLVNCIYNMRDKSDKSVKAAFASYYRQRHHEAEEMVKGSAFLTNVMNGHVSWKQTPFPDEHKLKELTPLIKPGSVLQFLPGAGQGAAMAMKDAVVLANCLYNMRDKSTMSITSTLAEYYRQHYSEANIVIKNSDIYTKMMFGYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MW26</accession>
    <name>A0A9P6MW26_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_010426</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CDC123 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000724">
        <property type="protein sequence ID" value="KAG0014459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15550">
        <property type="entry name" value="PHD_MLL5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009772">
        <property type="entry name" value="CDC123"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15323:SF6">
        <property type="entry name" value="CELL DIVISION CYCLE PROTEIN 123 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15323">
        <property type="entry name" value="D123 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07065">
        <property type="entry name" value="D123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20826">
        <property type="entry name" value="PHD_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SET" evidence="7">
        <location>
            <begin position="430"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="137"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="365"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="622"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1108"/>
            <end position="1139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1152"/>
            <end position="1220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1272"/>
            <end position="1341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1377"/>
            <end position="1673"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1692"/>
            <end position="1755"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1848"/>
            <end position="1880"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="1010"/>
            <end position="1038"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="27"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="64"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="157"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="177"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="201"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="228"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="256"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="292"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="365"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="622"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="642"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="700"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="731"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="761"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="791"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="815"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="830"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="861"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="910"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="944"/>
            <end position="958"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1195"/>
            <end position="1207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1286"/>
            <end position="1308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1395"/>
            <end position="1407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1426"/>
            <end position="1446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1470"/>
            <end position="1493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1517"/>
            <end position="1532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1625"/>
            <end position="1661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1855"/>
            <end position="1874"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0014459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="2058" mass="226084" checksum="18259CD5C95748CB" modified="2023-09-13" version="1">MSAKLSSTASSSSISNPTTKAIGRLANNGNSSSTNNNNSNNNNNNNNNNNNNNNNNNNNTSTIADEDEDSGENEEDDEDAGIIRCICNFIDDDGFTIQCERCFVWQHAVCVGIVQSNVPDEYLCELCSPRPVDRKRANEIQRRRNGTLERKKEKSPARRKPSVGRPRKQFGSGSGHSEQSPIPTSSSSNPKENGAHYSPVVNGTANGYQTKSTSSSLTDVSGKKVKPSSASGVNNNNNSNSSSSSNGKQVSQYPHTQNTNSTTSSTSSSTPSSNKQKPFAQVNGSRIHSTAIEDDDIDMESDSQEDVQDSYQSEFSSVETNIVTSKAVQDLFRQVISQFRQAQSRKRSLSLTSGAKLELVASSTTFSNNNNNKSSNSTATPSNSVGLDTSIGSQPPPLQPPSSSNTDPSNVVSMERESLARPLMKTTVKHILPSSKSPHSPASQYGLFAESNIGAGRFMMEFKGEVSLKSAYKADPINQYSILATPKPFVLFHPQLNLVVDARRSGNDARFVRRSCVPNTEVKSIVVPGVQDQTVHLGLFAKVPIGKGQEITLDWDWNMDHLALQSIKTSLEKSKESSTRKSIKEIRKAKYLVASTLLAQTDCACENKESCVLHQMFRDGVSESGARDHESSGSSKGNRPKKTAESLRQRYGGQRERSEGKRSADQETSDDDLSITESSPRRKSPKATNLENASKKPRHESHPTQRGSRPEQDVGSGSESDDNRRRKQTIQERQGSPSKRVNSTNPEMSAREMKQALMLIKKMEDRDTSTSGHDKQKSIDSKTGVSSPKPRARDKIRQTDSDLKPNTHHAKTNVNEDDNISIEDSGIDSDSNHGHPRRDTSSMDRATNSGNKRAFSAQGQGKREREQTEHDAPSQSPATSDSDRKESTRRLSRRPPASQSGKKQPYAAASREKRMVEQSRSKPISKHQTPQRSMDTLEDPQALSGSSSVEGSFVSIVGNTSDEDDDLNQKTTRRLLREKNLPKEVFPAASLRPSVLPCKKAWKLTYLKQRALAEEEAREKAEEMRKKAEEVFDLKMEEDEPVIDACESLSSNDIQTSMSHTSNTMGTDRSVELAVPIVLMKDSPTVDIQQPSMVEGDVLNLFHENVKPESNSSTADKRHQRSPSDKHAESTLSRPLIQQPVILKPLTATKELNIDSPGLSTGEQPRARQKMSLESYHARRLASGSPAISEDQPEVASTSVAAKTSTPIAPESTDVEMSEPDLVTDTQVSAPSALNDPISAISELTVTKTEVAPTIPKVKLSLQEYQKQRQEASQRIIGTPNIETPHQLKAEEESDEKLKDIGDLDTETRTAQGPELTDAEMSEKSQDPLDTDSQGRLTRRDYFQVGASLPTPLIGLSSRAQPVAKQAIKEYFPVQPFSPISLSAGPTPFSKLNLTSSPPRTSSSSESQIQLAGGPPIETKSPGKSPKSQRLQLNPNPKDSLDTNSPGAKVESSPPPLSQGTLGWRAPRNQRGQSPPGTVSAGSIGSFRGTSSEFRPMDSRSADTRLASPRYYGPPSERPERPLNSPTRERQHSLTSGGLPASPFDPGYSGTGGHYGYNDDLPQYKRSGHLFSPTGPAGLSGPREYYKSDDRARHRSLNGDEWNYGGVESPAYGGYRGPRGVPPLPRDRDRDRERDRERDHERDRDRDRERERRDRFDRRSDYFASGPLGGGAGINAVNNNSGFYGPNRGQGGLGGGYGRRPSDYYGGQGREEGHNNGGPNNSTINHGKKDGSSDNQPLSSEEEQDSQQEQNAGAAEVSTPLVFPPLTHQRLENCAFSAWYPAFRSITIKSKIIALPEDFIDYLNADGVFIPGQSGISMALSDSYSESDSEDQPKKSNMDKFEALKRESFRQAGENGDDSSDDDDGEDEDEDEEVPMPSFPALEREIQQTIDDLGGEVFPKLNWSSPRDASWIAASNTLKCHNPSDIFLLLKSSDFVAHDLAHAYEDCSDEAGGQVGSDVRKRPEVIDLVLRKWFDLAPSMEFRCFVRENKLIGISQRDMTYYDFLKGIQEELEQKIIGFYEDKIKGKFPDPDYVTDLSNGQTVADFAEAFYKKVQAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWE1</accession>
    <name>A0A9P6MWE1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">3-hydroxyisobutyryl-CoA hydrolase</fullName>
            <ecNumber evidence="3">3.1.2.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">3-hydroxyisobutyryl-coenzyme A hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_009974</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>3-hydroxy-2-methylpropanoyl-CoA + H2O = 3-hydroxy-2-methylpropanoate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:20888"/>
            <dbReference type="ChEBI" id="CHEBI:11805"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57340"/>
            <dbReference type="EC" id="3.1.2.4"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.4" evidence="3"/>
    <dbReference type="EMBL" id="JAAAID010000648">
        <property type="protein sequence ID" value="KAG0015216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWE1"/>
    <dbReference type="OrthoDB" id="1737613at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003860">
        <property type="term" value="F:3-hydroxyisobutyryl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006574">
        <property type="term" value="P:L-valine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.226.10:FF:000026">
        <property type="entry name" value="3-hydroxyisobutyryl-CoA hydrolase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045004">
        <property type="entry name" value="ECH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018376">
        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032259">
        <property type="entry name" value="HIBYL-CoA-H"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004127">
        <property type="entry name" value="PRK05617.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43176:SF3">
        <property type="entry name" value="3-HYDROXYISOBUTYRYL-COA HYDROLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43176">
        <property type="entry name" value="3-HYDROXYISOBUTYRYL-COA HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16113">
        <property type="entry name" value="ECH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00166">
        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl-CoA hydratase/isomerase" evidence="7">
        <location>
            <begin position="60"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0015216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="480" mass="53150" checksum="DA71AC9AC8781C46" modified="2023-09-13" version="1">MLRQTFRMTSASKVSPSIVAQHRIRMMNSWLGARVNMSTTAASNDAVEADVLHRKHLSSRTFILNRPKSLNALNLSMVRNMTPQLQAWDASDLCKVIVIKGAGGKAFCAGGDVRLVVEQAMAQKQDEGLTFFAEEYKLNHMIATLKTPFVAILDGITMGGGVGLSVHAPFRIATEKTLFAMPETKIGLFPDVGGSFFLPRLDGETGTYLGLVGTQLKGIDTVFAGIATHYVPSERLAALEDRLSELETDNHDVINMAIEDFVSEPKHGHKYALSENRDAIDRCFRFNTVEEILAALEKENTPFGTQTLKTLRSMSPTSLKVTLQQLREGANLGIADCFRMEHQLAGQFLYGHDFIEGVKALLIEKTLNPRWDPATVEEVDREQMLGVYFRNQPTKALSLTSNSSFREYPYRRYALPSENEIRKIVTGEAQGSGPLQLTADEVVEVCVKKSGGKIGVREKVLEVLSRKVTKGPDGELKWIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MWJ7</accession>
    <name>A0A9P6MWJ7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_009881</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000632">
        <property type="protein sequence ID" value="KAG0015399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MWJ7"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="314"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="428"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="503"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="575"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="622"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="693"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1037"/>
            <end position="1079"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="233"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="257"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="314"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="328"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="338"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="356"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="436"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="452"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="634"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="704"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1049"/>
            <end position="1059"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0015399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1171" mass="128068" checksum="AEBC961F4128B838" modified="2023-09-13" version="1">MATAGPQSATQLHSLHQKRYSRMENEPETPVPSSYPPLIPVPIDTIKQSALLNSIDTTIDRSVHRDNNGPTSELVSEPSSPSPPVLLHNTDLQASLQYLPDLASSPAKMNHLQGLMSSLHKIMNDQNFVLGDLRTQLDEIQDILNRVGSKQDSMSAEERKIIQNAQMLKSLAEDVIATNLTSESKKSIEEGQGKIHPLTISVPTPGARTIDSTETPPPTAITPPPGHLRHRSSTASFASSVSSDRQYTPDGEERTSRPSSVASSYRSKQKKKSLRQLEPLTSNRGSRYDVESNASFDRICSLLTELITDASTAVSTAPDGTQQPSTIPLPQLPSLEPSESESDSASDQDEDGDDSNNTLDSVENTVTTKETDDPFLKRLQVPESAQSADDAEVEVELEPVDRYRTGFRSRPDKSSKRLSSLFMELQNTQTIQGAAPKDEPAKEKVVRRPRRSISSMSISSTRSSRHNSVSLRSNESIEPLCSFESPLESPLITERIKQRNSISSIRSEPLQKLSARSESPVKQDVVDPELNRTVETIDGLTRDLVTVATHQNLMQMKLQKTLQFQKEQIQQIERAHSPSAVSLTRGVDEPHLDKQSDQRLLADLSRSLKQVAVSVGKVLANSASKAHRGGQSKEGQKELLENTEKPATQRVSRFSGKDFSQYFQELEKVAALGGRIGFGHGDVDGALKDHILEGSTDQHGKSGSAKSPNGSCRNSSAILVEEALVPVLDEPDVVLHSGSSSPKVYTTVSSRRGSVSAGPPDLEDFAAQCRLLTRALVLPFIQLTHHAMTSQDSAFALNPRSSKFSGPARDLDSTLEIVEDLDISTRENRPISPKFKPVAQKDSDSIPSLPGWSPSMTIAGRDLDSILKANEEMSPDAIVKAKTFISTGLYLLHLLYWTVLFVIGTVVLDSWLAETAGTQVVRIVDQVREAIAKEDPSGQRFHPIDQALYLQERENLITSDQRDPEAESILERGRLQAHEDRAIEVAVGFESLKNRLSGARASDTSSQSFKSPWNKQGNFQSTAAALTAATLSESKASSSSAEVHGKSPAHTTVSSNTGVLRTVSWVGPRKRRNTKDGVPSRVRRFSNTRTMTLTGPLLKTESVSTTVVPRRLGSRQDRPLSHWGSFGPTSVNTLTGFVSTDFTSQGLGNASQRLQIPQNVPKQVQVRRKSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MX28</accession>
    <name>A0A9P6MX28_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SAC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_009772</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000614">
        <property type="protein sequence ID" value="KAG0015578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MX28"/>
    <dbReference type="OrthoDB" id="405996at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043812">
        <property type="term" value="F:phosphatidylinositol-4-phosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046856">
        <property type="term" value="P:phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002013">
        <property type="entry name" value="SAC_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45662">
        <property type="entry name" value="PHOSPHATIDYLINOSITIDE PHOSPHATASE SAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45662:SF2">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-3-PHOSPHATASE SAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02383">
        <property type="entry name" value="Syja_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50275">
        <property type="entry name" value="SAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="542"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="568"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="domain" description="SAC" evidence="2">
        <location>
            <begin position="122"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0015578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="607" mass="68826" checksum="897A6A379B52C5DB" modified="2023-09-13" version="1">MAFHTNLKLYTSADIFTLEPYTNDGSAASENVVIERSSGAIRVNSPASKASSGDEVLNIYGVIGFIRLLLGEYIIVITERTKVGQVSGHDIFKVKDYRVLPLSRNNLTQTQIGEEASYLSLLHAHLQSANLHFSYGYELTHTLQRQSELKDNIQHIWERADERFFWNKRLQSKFIDHAASNKDQDLSKFILPVMNGFVEFKSAEINKKPFTFALFSRRSRHRAGTRYFSRGVDAEGNVSNFNETEQIVIADAGQDGSASSLPGGQIILSHVQTRGSIPIYWAQINNIKYTPKLKIFDNPETENSFRKHFETQKALYGPQLIANLINKGGYEGPMGVAFQKQIDILNDPQIKYLHFDFHHECSKMRWHRVSLLLDYFQEDLLSQGYFKAEISKEGVEKVEKKQTSVVRTNCMDCLDRTNVVQSVVARWTLNRQLRDIGILGADEKFEIFDEFESLFRNIWADNADVISCAYSGTGALKTDFTRTGNRTKAGALQDLQNSIVRYVKNNFLDGNRQDAYDLFLKYDVNPSGSYPLVDKRSLEIKALPALVPLSIVMIFGSIIFPKNSLNTTSILFISFWIAVLFYVLKLIVGNGGSYVNWPKLIPVPQKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MXB3</accession>
    <name>A0A9P6MXB3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_008361</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="5">Interacts with the elongator complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the KTI12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000450">
        <property type="protein sequence ID" value="KAG0017365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MXB3"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000827">
        <property type="entry name" value="KTI12 chromatin-associated homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025715">
        <property type="entry name" value="FoP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013641">
        <property type="entry name" value="KTI12/PSTK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12435">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13865">
        <property type="entry name" value="FoP_duplication"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08433">
        <property type="entry name" value="KTI12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01218">
        <property type="entry name" value="FoP_duplication"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="380"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="319"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="467"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="325"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="504"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00063730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0017365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="528" mass="58191" checksum="B8866F5E9FD719C4" modified="2023-09-13" version="1">MPLVILSGLPSSGKTRRAQELKQFFESRLADQSQEQEGSATKTKDYRIHVVNDESLNLNKHVSYNTAADEKKARGALMSAVERLLSKDDIVIVDSLNYIKGFRYQLYCVARAIGTPHCVVFCGCSPDTARQWNSVSGAYPEKIFEELVVRFEEPDSRTKWDSPLFIVVPEDIKLPEDEIWDAVILKKAKPPNLSTVVKVVKETNYLYEFDQTTQNVIQAILDAQKSGDPTKQIKAPLSSILLQLPPTRVVTLSELRRLRRQFTSINKMHTLLDMSRTFTSSLRNTLNTSNPTTSSNLPTQTSLAMSSALDMSLDDVIKTQKANRRNNAPRGGRGARSSGPARNTRHSRDNKPYQAGAQPYRNTAAPLHTAVLRQSAPDGSKMQVSNLDHRVSAEDLKLVFSSRVGPLKKCTLNYDQNGKSTGTAVVHFTRVGDAAVAYSKFNGVPLDGRPMRIEIVLAPAAAQAVLPAQAQGPKTSAPNQGNRNQGPSRGGRGGRGRGRGGRNQGEKRETKTADQLDAEMNDYMQVDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYM0</accession>
    <name>A0A9P6MYM0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BGZ80_006901</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000344">
        <property type="protein sequence ID" value="KAG0018657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031380">
        <property type="term" value="C:nuclear RNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031048">
        <property type="term" value="P:regulatory ncRNA-mediated heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17936">
        <property type="entry name" value="EEXXEc_NFX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06008">
        <property type="entry name" value="NF-X1-zinc-finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001660">
        <property type="entry name" value="NF-X1 finger and helicase protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF445">
        <property type="entry name" value="NFX1-TYPE ZINC FINGER-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="2">
        <location>
            <begin position="693"/>
            <end position="990"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase-like C-terminal" evidence="3">
        <location>
            <begin position="1005"/>
            <end position="1237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0018657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1429" mass="160542" checksum="4D7FAAFEB7E548FB" modified="2023-09-13" version="1">MTRSERGGGSGQRGGNDNNRSGGGGGRGGNRGGHRSGRITGSQKSQIVGSKRKETLQISSEGTDDVIIAAPADEDLQHFASFVLQKKEFVAFNGQRQIRKFVNSCLLNLSNHHNIDTTGILTDLASAQGRRRTMDILEMRMGVDAADDKNILSFQYVILPFIGVLTRESVCQSTMTSESGIIYSTVYMNRGLFLEKGVLPCMGQLIERRSVKDTSMAAQRLLQQEPSICQPSSLQAALLAITRLVYQLIKRTQDARIEMAGVVQTLYEQQMRCVQVSDDSAENRFINEVLEREVTRLRHIIADAQDTIIHPISPLGPMSENRSRRGPNKVHIKLAYDPPGELSKDGPRHDNDDPEISRIKLLPTQEEIVCSRTPFLPSNGIHDAPHFLPHGWRRQLDTHFRLYREDMLDPLRKGIMGFLNALERTGKGNEDILLKQKELRKYIDDNVNLTVYGNVQFMGMNCTKQLSGSVDIAFAQPPSLVGASHKKRTEFWDRAKKRVMQGALVCITSRADDDTAARNTGSKSFQMILGVVTKRDPEILAKDPNFAHIHISLTDPKNYLVMLNSTTQSNSTQWFLVESTGGFYGSYSPILKALQKCVPASLPFGKYIAPSITDLNNVQANEKPTIDPPLYARAPRFTFDLSVLLKGLPCRLNVSDPYSVRIVEADLQSYSTLDKTQATALVETLCQYFLNCRPPGTGKTKIGVDLMRVLLHNKAAMNCGPILCICYTNHALDQFLEHLLDEGITSIVRVGARSKSDRLEDYNLERLMQSRDKPFSVRQSLRAANEKWDVVSAQITKLERALRDENLHWEWITGKDIDEKIQYNERLEAPNIANVNSFGVLDEDLGIFNKPRALRIPSYDRPLRQLHGNVWDMSKSERKRLQESWKPEVQKFMMDKMAQLLEEVEKINQTKNNAFDDIRRGILKDTSVIGMTTNGAAKLQTLVGAVAPKIIICEEAGEVLESHILAALSTSTQHLILIGDHLQLRPSIESYNLSSDSPIGQNYNLDKSLFERLVTDTVSPFPLSKLTIQRRMRPEISSLIRNTLYPNLEDGEAVFRYPPVGGMAKNLFFMDHLHPEDSKDQYGMQSFANTFEIKMVEALAQYLIKTGYDQPGDIAVLTPYLGQLSKLRDHLRSSFMLTIDERDQEQLDEKDAEDENNNVNESVGVKRIGLQKHLTLRTIDNYQGEEAKIVIITLVRSNAKENGALAASSSIGFLKSRNRTNVLLSRAKHGMYIIGNASLMENAKNELWPKIIQELRQHDRVGDGFPIVCKNHPHIKNIVSEPKDFKIVSPNGGCTAACGRSMPCGHTCPQHCHPDDVDHILVKCFEPCPRLHDFCEHVCPKLCGEKCGNCMEIVAPMVLPCGHIFDKPQCWQSRNPSKVTCQVKVIRKLPTCEHEQVVHCNVDIKTMSFASGHALNARMPLFRRKVHLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MYZ7</accession>
    <name>A0A9P6MYZ7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Integrator complex subunit 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">INTS1</name>
        <name evidence="2" type="ORF">BGZ80_007587</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000391">
        <property type="protein sequence ID" value="KAG0018075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032039">
        <property type="term" value="C:integrator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034474">
        <property type="term" value="P:U2 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038902">
        <property type="entry name" value="INTS1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21224">
        <property type="entry name" value="INTEGRATOR COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21224:SF1">
        <property type="entry name" value="INTEGRATOR COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="85"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0018075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1331" mass="148582" checksum="14FD53FA03968A0C" modified="2023-09-13" version="1">MSKEPRKGKGTAPERNLPDLIPLGRTPTRPIKSSSKLEPQQPKSLSNASGASATHTLPLDSSTLNTPDSPIDGVPTPPPKRARIGSTSTGSGSAPSTPPRIKNEESTLKSALRKVPTQQQSTVQQSPQQYQQTRPQSLWTISRNVKVEQETGHVNLRQVDEEVYNTFQQPSWEVPPPLQHIRAALQYLKSNALKPDPVITSGLLRLGQAMPELLREQTIAAIMIQLLRPEFTHTFKIRTNGAVVFLICALLHLAWDSIDDWPTDFVMAYLEDALGERSWCASADTKEFVGNILTAFRTDEPIDDTGEVKYDPVRLDEKTSTSAVMVTIDFHQYTESLSLRRRYQDQAVRNNIKHIALQTMWEHLPMAVGASAVEAPVRSLIKVMMVTCQWPEVRLKAMGCMEFWLGNFMKSAKPLLRLILRQISSQETMSRDDLETWSMLLDFRYKGRTHQVEAVKEELRFALIGLAGQEMIRTGLSHIMDVEMNPNELKNPYHLDLMELFLEAIPNKPAVEFGQLIQGCTVDAALHLAGSTISPPLAPVVLVVKRWIRHLGKRSTSWTADVIAGLLKEGPHLARLVQKQEHHQQPHIPPGGRNTPTMWLLMLIEIVCNVMMATAIDAKEMKDIKVSKFSIESAHTFTLRWFQVISSATAVTAAPSEGDVCKTPFGPVPLDALRICVARLLFLDPPQSYAMDTTSQEFDTSLIYKVIENGLPLTEAGLFALLDIRLPNKMLLSVVGEILALVVWDSMPVIRMLLELCISQHYSFPPPNYTSRSEPSSERLLRLGIQADQKDRDLVLAWEKEAMIVEGQWSEARGNSALQPSESEYVGWLMRLDFGPSQPARAPPPEIMLQLKGMNERFGLGMKLASTRDPDYLGRMVGSNDDAAWVDQLLRDVPEILNALPAATLCARYLRSIVTAQKDATEVVGTAATEIGSVDSSVKMKLMGYLENVMDTNAGHVGVLNSQSEPSARFQEVRDIFEYFLVRTCPSPSSSVVEAETIVLETKLAMSALFQGSLHWPSVLIQTVRKTPNTGFFSKALQWIESLVAVENDVKWIMPCLEFLLRVDGGDEDQSLEQSLLTLATFLTSRLFVFDWIIREQDGILKELAKRVDEYFARHDSIMEDVLMKGVDSSSGRTSTKSNVQVELFGGTVLSTYPEILRLVLLILSVGDVNKQESGQNVSHAPKKLTNGATFLYSDPPMPNDMLLRLRLVQTSREPEVVRAAMDGLNLVQVIDITKDAFGVDIKTAQIIHEALLVALEQEKAHGVPIHLERSTSKRLELLLSYYADRGGQFSKQALEIVRSRFSLESLSYMESDTKVRESVVLPDFFQMAIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZ28</accession>
    <name>A0A9P6MZ28_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Arf-GAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_007074</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000356">
        <property type="protein sequence ID" value="KAG0018519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZ28"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.150">
        <property type="entry name" value="Arf GTPase activating protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051718">
        <property type="entry name" value="ARF_GTPase-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037278">
        <property type="entry name" value="ARFGAP/RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001164">
        <property type="entry name" value="ArfGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038508">
        <property type="entry name" value="ArfGAP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45705">
        <property type="entry name" value="FI20236P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45705:SF1">
        <property type="entry name" value="FI20236P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01412">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57863">
        <property type="entry name" value="ArfGap/RecO-like zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arf-GAP" evidence="2">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="350"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="94"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0018519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="375" mass="39474" checksum="287E713B6FACA324" modified="2023-09-13" version="1" fragment="single">KSVDLDSWTVEQVENMIKWGNEKVNMYWEARLPANSIPNESTSGIDPWIRSKYEHKQFSRKSSLPDPSELGPIDEAILMELYGKSDSHLKPNRSAASSGSFSGAALTPPPSNPARPSFPKKPASSSLQGADLFSIGQQPSPSKAAAAQVDFFGLNDPVPTQAAQVQSTKAATNTSSQDLFSITPATATAPASAAPTNNQAAASKPANTDWKNSIMSLYGNQPSAPKPNPGGFNMGQSSAPFGQLQGMDAFGFGQAPIQQQQQQQQQQYNPWGNDDAFGAMQQAGASTSNSSFDAFGSNFSSNNNNGFGTGSNSFGTPVSAPGFMQANGGQINGVNNGVPQGGDFFNLIAGATRSPTTSTPQNSNKSNSFSDLKWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZ81</accession>
    <name>A0A9P6MZ81_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Creatinase/aminopeptidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_007802</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M24B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000406">
        <property type="protein sequence ID" value="KAG0017896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZ81"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01085">
        <property type="entry name" value="APP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.350.10:FF:000003">
        <property type="entry name" value="Xaa-pro aminopeptidase P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.230.10:FF:000007">
        <property type="entry name" value="Xaa-Pro aminopeptidase P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000587">
        <property type="entry name" value="Creatinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033740">
        <property type="entry name" value="Pept_M24B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032416">
        <property type="entry name" value="Peptidase_M24_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050422">
        <property type="entry name" value="X-Pro_aminopeptidase_P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43763">
        <property type="entry name" value="XAA-PRO AMINOPEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43763:SF6">
        <property type="entry name" value="XAA-PRO AMINOPEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01321">
        <property type="entry name" value="Creatinase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16189">
        <property type="entry name" value="Creatinase_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16188">
        <property type="entry name" value="Peptidase_M24_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Creatinase N-terminal" evidence="7">
        <location>
            <begin position="14"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M24" evidence="6">
        <location>
            <begin position="259"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M24 C-terminal" evidence="8">
        <location>
            <begin position="488"/>
            <end position="550"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0017896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="550" mass="60883" checksum="22268E17EDD263C2" modified="2023-09-13" version="1">MSSATVTATDTSDRISKLRELMQSPEYNVNAFVIPSEDAHQSEYVAECDERRAYISGFTGSAGLAVVSLDSAALFTDGRYFLQASQQLDSNWTLMKSGLPNVPTWQEYLVKNLPPGSRIGIDPLVFTAADATKLEKELSKSGSSLIPVPNLVDFIWTNRPSRPAHKLLTLSTATTGRTHAEKIAQLRQELEKKAVVGCVVSGLDEIAWLFNMRGSDVHCNPVFFAYAIVTQVALGKENIVEARSPVTDAKAIKNNTELEGMRQCHLRDAAAVINYFAWLEDQLSTGSRLDEADGAEQLQKFRAEQKGFVGLSFDTISSTGPNGAIIHYKPEKPTASIIDPKLVYLCDSGGQYLDGTTDITRTLHFQTPTAHEKRCFTRVLQGHIAIDSAIFPDGTTGYSLDILSRRALWTDGLDFRHGTGHGVGAFLNVHEGPHGCGPRPAYNEVALVPGMTLTNEPGYYEDGEFGIRIENVLLVRKAKTEHRFGGKEYYGFEHITFVPIQTKMIERSLLTSAEIDWINRYHAECLEKVEPYLEKGSLGYEWLKREAVPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZA6</accession>
    <name>A0A9P6MZA6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Ras gtpase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_007492</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Golgi apparatus membrane</location>
            <topology evidence="7">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000385">
        <property type="protein sequence ID" value="KAG0018167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZA6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01868">
        <property type="entry name" value="Rab11_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000067">
        <property type="entry name" value="ras-related protein RABA1f"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050209">
        <property type="entry name" value="Rab_GTPases_membrane_traffic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47979">
        <property type="entry name" value="DRAB11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0636">Prenylation</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0018167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="210" mass="22751" checksum="F845E19ABA562BED" modified="2023-09-13" version="1" fragment="single">MTDYYDYLLKIVLIGESGVGKTNILSRFIRNEFDLESRSTIGIEFATAKSIEIDGKIARAQIWDTAGQERYRAISVAFYRGAVGALLVYDISKASSFQNLERWLSELKEHAGPNIVLALIGNKSDLRHLRAVGTEDGKALAEKHNMLFLETSALDGTNVQEAFSEVVAEIHKAILTSTPTGGGIGLKPGHGKTVIPLTSISPTDKANSTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6MZX0</accession>
    <name>A0A9P6MZX0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Tubulin alpha chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">TUBA3D_1</name>
        <name evidence="18" type="ORF">BGZ80_006587</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the tubulin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000326">
        <property type="protein sequence ID" value="KAG0018892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6MZX0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005200">
        <property type="term" value="F:structural constituent of cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02186">
        <property type="entry name" value="alpha_tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.600:FF:000005">
        <property type="entry name" value="Tubulin alpha chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.20:FF:000001">
        <property type="entry name" value="Tubulin alpha chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1440:FF:000007">
        <property type="entry name" value="Tubulin alpha chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.600">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="entry name" value="Tubulin/FtsZ, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="entry name" value="Tubulin/FtsZ, GTPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002452">
        <property type="entry name" value="Alpha_tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000217">
        <property type="entry name" value="Tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023123">
        <property type="entry name" value="Tubulin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017975">
        <property type="entry name" value="Tubulin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11588">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03953">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01162">
        <property type="entry name" value="ALPHATUBULIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01161">
        <property type="entry name" value="TUBULIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="Tubulin C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="Tubulin nucleotide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00227">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="11" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0493">Microtubule</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRCT" evidence="17">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="160"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="195"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="169"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="197"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="219"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00034296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00071544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAG0018892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="759" mass="84565" checksum="4CA702301F2B527B" modified="2023-09-13" version="1">MFKGYSAWFSPELASYKQPWRNHGGEEKGLAEADIAFVSDQTYSESDNTKPTMKILRPDWIEDSIQSKKRLSLKRYKRTFPALDGWNTSSCDDNMAVGMEAYTSTKMLVFKPLSEHLYQPEPGIQDLSVTDNSAITPSIGNHIEEFEDTIAQNESIESVAKETQDLERTQTLPTPINDGQQDKFLDTSIEVSGEPSFVKDTRSDSEHEQVHENAPGSVVVSSASLSNPPMSPAKRKRRLPETVWRTKRPPPAVRDTQVGDDFFGSSSSEDEDRYQRAKRYLPSRVDADADANADNVQGDATMPTVEPLHRKQAVQESIHVGQAGIQIGNACWELYCLEHGISPDGTISSDEQAKRFDSTSSTFFSETGAGKHVPRAIFVDLEETVIDEVRRGTYRSLFHPEQLISGKEDAANNYARGHYTIGKELVDGVLDRVRKLSDACTGLQGFLVFHSFGGGTGSGFGALLLERLSVDYGKKSKLEFAVYPAPEMATSVVEPYNSILTTHTTLEHTDCAFMVDNEAIYDICRKNLDVVRPSYTHLNRMIAQVVSSITASLRFVGSLNVDLTEFQTNLVPYPRIHFPLVTYAPILSAKKAFHEQLSVQEITSACFETSNQMVKCDPMQGKYMACCLLYRGDVIPKDVTAAIANVKTKRTIQFVDWCPTGFKVGINDQAPSVVPGGEVAKVQRAVCMLSNTTAIAEAWSRLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGSDSMQDEEEVEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N041</accession>
    <name>A0A9P6N041_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Eukaryotic translation initiation factor 2C, 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">EIF2C3</name>
        <name evidence="4" type="ORF">BGZ80_004361</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the argonaute family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000223">
        <property type="protein sequence ID" value="KAG0020347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N041"/>
    <dbReference type="OrthoDB" id="10252740at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02846">
        <property type="entry name" value="PAZ_argonaute_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04657">
        <property type="entry name" value="Piwi_ago-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.260.10">
        <property type="entry name" value="paz domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014811">
        <property type="entry name" value="ArgoL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032472">
        <property type="entry name" value="ArgoL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032473">
        <property type="entry name" value="Argonaute_Mid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032474">
        <property type="entry name" value="Argonaute_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003100">
        <property type="entry name" value="PAZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036085">
        <property type="entry name" value="PAZ_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003165">
        <property type="entry name" value="Piwi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045246">
        <property type="entry name" value="Piwi_ago-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22891">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08699">
        <property type="entry name" value="ArgoL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16488">
        <property type="entry name" value="ArgoL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16487">
        <property type="entry name" value="ArgoMid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16486">
        <property type="entry name" value="ArgoN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02170">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02171">
        <property type="entry name" value="Piwi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01163">
        <property type="entry name" value="DUF1785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00949">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00950">
        <property type="entry name" value="Piwi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101690">
        <property type="entry name" value="PAZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50821">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50822">
        <property type="entry name" value="PIWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAZ" evidence="2">
        <location>
            <begin position="219"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="Piwi" evidence="3">
        <location>
            <begin position="516"/>
            <end position="817"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU361178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0020347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="851" mass="94928" checksum="64E8B41251B651B5" modified="2023-09-13" version="1">MSETLKLTELVKRPAVGKAGKPITVKANFFEIQRLPDITVFHYDVTISPEDLPPVVNRKIYDDFITTYGKSELGGARPVYDGRKNLFSAKELKFDSKTFDITLDKIAQPNPKRPVEVFKVKIRKVATINLEELHRFLTKKSAMTNNILTGIMALDVLIRHKPALLYATVGSSFFTPEGKQSLNGALEVWRGFYQSARPAVGKMMINLDVSATAFFQPGSLIEIVIKVLNLRNPNDLGRTSPPLNWSKVEKFIKGLRITLTHRDKSKKGFKIAKLVQKSARQYKFKVDSNKADAQGKPTQVETTIEAYFQQTYGRKLQFPNLPCVAIGKTAIVPMEVCSVVEGQRYPKKLDDKQTADMIKFTCQPPHVRANTIKDGLRILNYENNEFLKDFGLKISTEMATIKARSLPPPVISYHPSSKDANFTPNDGAWNLIGKKVAQGTTLGSWGVVVFGNERDVPTDQANGFIRQLVVTCTATGMNIPNKSPPIVYANPHGDIEGALRQAWQRAGNAVKSQPQLLLCILPTTGVPLYAEIKRVTDTVLGVSSQCIQVKHTRDPRPQYCANVCLKINVKLGGMNSHLAGNMLPFLTSKPTILMGADVSHPAPGDTVRPSIASLVGSMDAKASRYSASIRVQTAKTETIADLTDMAVELLKTFYQTCGRKPERIMMYRDGVSEGQFKEVLEKELAALKAACHRLEATYNPKITFVVVQKRHHARFFPMRREDGDRSGNCKSGLVVDTDIVHPCEFDFYLQSHAGLLGTSRPAHYYVLYDDNKFTADEMQEFTFRLCHLYARCTRTVSMVPPAYYAHLVAARARFHSKNEQWSDSASTESGVGDASSYGRLKPELAKVMWFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N052</accession>
    <name>A0A9P6N052_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_006454</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000319">
        <property type="protein sequence ID" value="KAG0018985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N052"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="146"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="279"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="367"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="453"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="521"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="52"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="78"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="90"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="280"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="367"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0018985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="723" mass="78304" checksum="A9FB46F4F20CF348" modified="2023-09-13" version="1" fragment="single">SFAKRISHLFGRSKSSKKISVVSNSENTTSAASIKETGAQDLLPPSGAFHQRSCSSPDVRKTSSSNEASADALDTTGAGVSSSRNSMILENRDRKARDSGFEDLEGHRRYSSTPSVVAVPRPPRLNPNQRPHSSYTLAGWDNMFMDQQQSPNSPSLPYSGNSLENNRTPMDAKFRSRRSTLVDPFIHEPPQALINAAPRRSSAPVITETLVSRIDREKSTICFQAPSAKQEYTREGSLDPALSSLAQQHRRDLQTNARLGGAGVAPQAQQPQQQVIDYQSGRDRDVRGAAPPRRDSGNPQISNSPLHHPANTGLPTSSVPGMHPLELNNKRISVCYQQPPLAAHSVHSAAAKRMSYIGNNSTLLNAAANSAKQQQQQQQQEQLQRSSPQMTPQLGGHGSQGMHRTSPNRHSVIGYFNLPQHQQQQGYIQPSPVPSPVLGAASFAYGHELSVAMQHQQQQQQQVQLQIQQQQLQQLQQQQQQQQQVYQAAVSPLTVLQHPDTTTTIAATAAQQLQLQQQLVVQQGQQQLEQLQQLRIQQQQQLILQQQQQLQQQLEQTRAAVAVASTPLLTPALTPALTPTETSEIAVTEAAQPSPQAVINSVPVHFTLPAAPVLTSPMGMNMNMNLVSMGMNPLGGYGQSATPMMTTTTQGMFPQLVMAPQVTPQLTPQLTPQLVAFPNTQQLYSFQQQQLLAGSGMGGIGSGSGDITAMTPMVLAAGGSASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N091</accession>
    <name>A0A9P6N091_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_005133</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000255">
        <property type="protein sequence ID" value="KAG0019876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N091"/>
    <dbReference type="OrthoDB" id="5580129at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0019876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="160" mass="17349" checksum="7E9581759843F242" modified="2023-09-13" version="1">MATVSSEFQSLGLTFQNLRQIKGHWDGGEQNPAVDNFNGEKHQALQKLGEYFGKPGTPAANILTTMGQPDEIKQTMDEAFHASLMPGPALGGAGANASANATGAGLGDFSTTVMPSGSSNAGPQVMYFVYKWRGNHDYLWFKIDALKEEVLESSWYHAYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0Q5</accession>
    <name>A0A9P6N0Q5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">LUD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_005805</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000286">
        <property type="protein sequence ID" value="KAG0019440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0Q5"/>
    <dbReference type="OrthoDB" id="15060at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003741">
        <property type="entry name" value="LUD_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36179:SF2">
        <property type="entry name" value="LUD DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36179">
        <property type="entry name" value="LUD_DOM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02589">
        <property type="entry name" value="LUD_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LUD" evidence="2">
        <location>
            <begin position="42"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0019440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="234" mass="25331" checksum="DD63916B374E88F8" modified="2023-09-13" version="1">MSIPQNTNLKETHAELTKSDEKVQSLASSHYSKPASAERINAAKAALEANGFKVYVVNTRADAFEAVKNLIPAGKSINNAHSTTLEEIGFITYIKGETPWKNVHGDILAEKDPVKQAELRRIAGSTVDYYLTSVASITETGHLAHGDLSGSKVGGVAFGSANVIVVAGSNKIVKDELEAWKRQEEYALPLESARVRIAYGLPASAITHYEVIRKANPFNANRIQVIIVNEALGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N0W4</accession>
    <name>A0A9P6N0W4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000262">
        <property type="protein sequence ID" value="KAG0019759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N0W4"/>
    <dbReference type="OrthoDB" id="2444720at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0019759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="244" mass="26432" checksum="11410D0453036E6F" modified="2023-09-13" version="1">MSMSLSPALSLSSPCSSLSYTPESNKPRHSNGYHNRTTSESILFTPPLSPTEEQLLAFLIPDIEPSELAAYLSAPSTPILSDVSCLIGNNTPIAEDHCSSNSQRFDAEAVYPSPVCAAAAATVVAIDRLDGGFHPTVVSSTPESENLNSMSQFRKKRCSTYAFMSSDDEDEESVASSDFPSCPVYVMSSRNTRKRLMLEQAFVSPDDEDYNQNCYAQLFQGASSDEMDSTSDLTSTLAFDLVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N157</accession>
    <name>A0A9P6N157_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Methylthioribose-1-phosphate isomerase</fullName>
            <shortName evidence="3">M1Pi</shortName>
            <shortName evidence="3">MTR-1-P isomerase</shortName>
            <ecNumber evidence="3">5.3.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">S-methyl-5-thioribose-1-phosphate isomerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">MRI1_2</name>
        <name evidence="3" type="synonym">MRI1</name>
        <name evidence="4" type="ORF">BGZ80_004941</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>5-(methylsulfanyl)-alpha-D-ribose 1-phosphate = 5-(methylsulfanyl)-D-ribulose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:19989"/>
            <dbReference type="ChEBI" id="CHEBI:58533"/>
            <dbReference type="ChEBI" id="CHEBI:58548"/>
            <dbReference type="EC" id="5.3.1.23"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 1/6.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.23" evidence="3"/>
    <dbReference type="EMBL" id="JAAAID010000247">
        <property type="protein sequence ID" value="KAG0019996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N157"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046523">
        <property type="term" value="F:S-methyl-5-thioribose-1-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019509">
        <property type="term" value="P:L-methionine salvage from methylthioadenosine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.420:FF:000003">
        <property type="entry name" value="Methylthioribose-1-phosphate isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.420">
        <property type="entry name" value="translation initiation factor eif-2b, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10470">
        <property type="entry name" value="Translation initiation factor eif-2b, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01678">
        <property type="entry name" value="Salvage_MtnA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000649">
        <property type="entry name" value="IF-2B-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005251">
        <property type="entry name" value="IF-M1Pi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042529">
        <property type="entry name" value="IF_2B-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011559">
        <property type="entry name" value="Initiation_fac_2B_a/b/d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027363">
        <property type="entry name" value="M1Pi_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00524">
        <property type="entry name" value="eIF-2B_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43475">
        <property type="entry name" value="METHYLTHIORIBOSE-1-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43475:SF1">
        <property type="entry name" value="METHYLTHIORIBOSE-1-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01008">
        <property type="entry name" value="IF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="1 3" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="236"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="3">
        <location>
            <position position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0019996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="378" mass="40723" checksum="9A9E4020FB12C94E" modified="2023-09-13" version="1">MTGATLQAIRYKRGSLEILDQLLLPHETVYIPISSLALGHDAIKTMKVRGAPAIAIVAALSLAVVLVQPTTEPQVQTTKDAVAFVENSLEYLKTSRPTAVNLFDAAHKLAKGVQEEASKPGVTGADIVNKYLELSERMLEEDVKDNTNIGKFGAEFILKVWKGGDDLRVITHCNTGQQKLTHAYCTETRPYNQGSRLTAYELVYEKIPATLITDSMASALLAQNEDKIAAIVVGADRVAANGDTANKIGTYQLAITARYHNVPFIVAAPSTSVDLNISSGKEIHIEVRPAVEVTTLRGPVVELSSISKGSNDVEFKNQDGSAVSETIAIAARGIGVWNPSFDVTPAELISAIVTEKGVVLKEDGVQEFDMKAFLHPFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1E0</accession>
    <name>A0A9P6N1E0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_002148</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000152">
        <property type="protein sequence ID" value="KAG0021573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1E0"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0021573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="261" mass="28663" checksum="898F5BDBE1A78362" modified="2023-09-13" version="1">MEPDRPYPERAHPPHNSGISSGGGHAKTKSRGQTDTAPVNHPSQHEKSSQRGNRGKGKDQQKRQSKDQPDQPETNADDEGSTTPWWEQSTYGKSKKDESKSESALQSTKESMEHKHINTVGTDTKESVEIVPKSKKSAKTTSEESEVPWWEQSTYKVKPKNSSVDQVSSGLANVSLSRSDSASEQRGDETMARRKALGKVTPTSGVEALTLVSREGDATGDYGEDTLCFTKPKISLLASWDNGSDYSIPLLFLLKLQCQML</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1M0</accession>
    <name>A0A9P6N1M0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_004101</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000213">
        <property type="protein sequence ID" value="KAG0020498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1M0"/>
    <dbReference type="OrthoDB" id="2420541at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5040190595" evidence="1">
        <location>
            <begin position="20"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0020498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="162" mass="17140" checksum="E9C9C5A0C6179222" modified="2023-09-13" version="1">MYTRSQFSVTFLLLLAALAIVPNNKDYLVSAQFGLSVACNDCLVSKISTLPSCVGVNLTDTAAQSTSQYGTCLCDSSFDFNWTTPCITSCQTNEIQNFETNFPSLLKTGLNLTCVKPTPSPTSSSTTSEASAMFTSVDSIALLGWTMVAALAITTSGLLTTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1Y9</accession>
    <name>A0A9P6N1Y9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cord and cs domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BGZ80_003468</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000192">
        <property type="protein sequence ID" value="KAG0020847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1Y9"/>
    <dbReference type="OrthoDB" id="1898560at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06466">
        <property type="entry name" value="p23_CS_SGT1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1130.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007051">
        <property type="entry name" value="CHORD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039790">
        <property type="entry name" value="CHRD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007052">
        <property type="entry name" value="CS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46983:SF3">
        <property type="entry name" value="CHPADIPLOID STATE MAINTENANCE PROTEIN CHPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46983">
        <property type="entry name" value="CYSTEINE AND HISTIDINE-RICH DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04968">
        <property type="entry name" value="CHORD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04969">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51401">
        <property type="entry name" value="CHORD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51203">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CHORD" evidence="6">
        <location>
            <begin position="4"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="CHORD" evidence="6">
        <location>
            <begin position="144"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="CS" evidence="5">
        <location>
            <begin position="220"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="69"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="83"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0020847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="346" mass="37594" checksum="2E0B87E6AD22AEDE" modified="2023-09-13" version="1">MPVCTHRGCEQSYDEATNSDTACTFHPQGPIFHEGLKGWSCCSKRVVSFDQFLAIPGCSVGRHTDAPREEFAPASSSEKVEVESVTPAAPAPTAVDKNGTETYGSAPAVATPVVKPAPAPAAAPEPIVEDEDDLSIPVSVGKTCMRRGCGHAYVSEEVSRGDKASCQYHPGSPVFHEGSKGWSCCPRKVLEFEEFMKLKGCRTTNQHLFVGSKKEKVEELVHCRHDWYQTQTHVNLSIFAKKVDAKSAIIEFKEREVSIDLKMPDEKRFKLELPLFQPIEPAGSSFEVLGTKVEIVMKKGNGISWATLEPSEGAKCWTTFGTTGGAGTVGSKVMHLATDSPLYAEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N1Z5</accession>
    <name>A0A9P6N1Z5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cytosolic factor, phosphatidylinositol/phosphatidylcholine transfer protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">SEC14</name>
        <name evidence="3" type="ORF">BGZ80_000691</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000115">
        <property type="protein sequence ID" value="KAG0022245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N1Z5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.20">
        <property type="entry name" value="N-terminal domain of phosphatidylinositol transfer protein sec14p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011074">
        <property type="entry name" value="CRAL/TRIO_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051026">
        <property type="entry name" value="PI/PC_transfer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45657">
        <property type="entry name" value="CRAL-TRIO DOMAIN-CONTAINING PROTEIN YKL091C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45657:SF1">
        <property type="entry name" value="CRAL-TRIO DOMAIN-CONTAINING PROTEIN YKL091C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03765">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00180">
        <property type="entry name" value="CRETINALDHBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM01100">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="2">
        <location>
            <begin position="86"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="261"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0022245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="282" mass="32219" checksum="F5CE848105CA6D0D" modified="2023-09-13" version="1">MSEVEVLPGRVGNLTPEQQHALDEFKQLIQAEGIFVEGRHDDHLLLRFLRARKFHIGHTHKMFVDCENWRKELGVDTLRETFVFEEEDAVRSCYPRYYHNVDKKGRPIYIEHVGVIDIKTLFKVTDEERMTKQHVLSYEVLITDRMPACSRKAGHHIEQCCTILDLKGVSLRQFANAFGFIKRTSAIAQNYYPEMMGKMYVINAPMMFTSVWGMVKPLLDEVTVKKIVILGSNYQSTLLEDIAAENLPKSIGGTCECSNHGGCQKGEPGPWKDPEFANPTKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2H7</accession>
    <name>A0A9P6N2H7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Cytochrome c oxidase assembly protein cox11, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">COX11</name>
        <name evidence="13" type="ORF">BGZ80_011238</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
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        <text evidence="1">Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
            <orientation evidence="2">Intermembrane side</orientation>
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        <subcellularLocation>
            <location evidence="9 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX11, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="5 9 10" id="KW-0238">DNA-binding</keyword>
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    <keyword evidence="8 9 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
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        </source>
    </evidence>
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        </source>
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        <source>
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        </source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
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            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
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            <dbReference type="EMBL" id="KAG0022758.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="725" mass="81429" checksum="2A1F69EBCE1B1832" modified="2023-09-13" version="1">MSLSPPPTDSISSVCSWLGDIVPTLSTLSCPTEVLLSPTAVRFDSAEYPKHIDTAASTNLDESNLGIKPDLGFQHNPCLLGDPHSILPTEEVSRSLLPPALNTSRAAMAPHILQSTIPEGANFPMTAVMPSGLIDQNDITGMPQEVRLPPCPEGGLYALDTMTAPQSSVANMEVTWDQVVGMYPAIGFSNPQSPDVEAKSMAAWDFVNNRTPFYDQIHSRHPTKAPLPDGQTKQAPTEQYNRRHTQPQLWVDDFDFLHRLAWENGESQSNFGIYACSQRQRPHLQHRQQPQMELQSYINIGPNPNLKQAHHPFLPSSPTLHRRRQYKPHSIFVASPTPLLKRRRRLTPEESEFLLHQFRINERPTAQEREAIAKYLKLDKRTIQVWFQNRRAKLKRDERDEGDGSPYEEHGCERLRAQGVKTDLSPAVSEDVADDEDGSETEVLTSINTMENEGLNLDDALEDYYWLESETLLGDKPVLSKIANRHPASVQHHSIMSHHVKRSYATPSATPPTPNPSNYTEALGSRKRVKAKNTDMLYYTASILIGTLGLSYAAVPLYRMFCSATGLGGAPMVGETKFAPERLVPRDNHRRIKVRFNADTSTSLQWSFQPQQRQVSVLPGETALAFYTAKNKSKEDVIGIATYNVTPSKVAPHFNKIQCFCFEEQKLMAGEEVDMPIFFFLDPEFANDPDMADVDTVVLSYTFFKARGMPFEKQPSLAEQQQQHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N2N5</accession>
    <name>A0A9P6N2N5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_011541</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000094">
        <property type="protein sequence ID" value="KAG0022660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="InterPro"/>
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        <property type="term" value="F:zinc ion binding"/>
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        <property type="project" value="InterPro"/>
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        <property type="project" value="InterPro"/>
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        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
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    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF37">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
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    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="17"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="135"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="627"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="815"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
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            <begin position="897"/>
            <end position="962"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1049"/>
            <end position="1087"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1214"/>
            <end position="1272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1322"/>
            <end position="1355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1435"/>
            <end position="1456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="640"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1049"/>
            <end position="1062"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1068"/>
            <end position="1087"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1214"/>
            <end position="1245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1258"/>
            <end position="1272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1332"/>
            <end position="1355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0022660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1456" mass="159617" checksum="A89994E4B8382FEC" modified="2023-09-13" version="1">MIVNNISGSKKQKTTPPCDRCRQRRIKCDRLQPTCSSCIKYKATCVRTAFPAGVPLSTVSVDAIGNPGLRVLTSGKRDRHLAEADILESCLRDVQSLQMNRLRRIEQFLDKLGIDETRLDEVSWLADQIKMQQESNPGSADIQYRPEEPSQAHTGAGNALQATLSESGNFICPAPKPTPFPSRVPLSVLNKTMFELSVYDSTQYLGPVAGTKASSWSEEMRFPIPWLVPEPKVQESLLVLPPLGQMLELIEWMIQSPLYTYFPILTKASILNALSSAMVGPDASSIDTDKPQGHDGMAEDTTALPQRITGRVSAVFLLNAIMALGAAYRSNAIKENKPHRLLSDPKSREKNLQDFQVFFDRSRALTVYILDQPRVSSLQGLLLLMKCPAIPGIQNLYREQACAMALSLGLHRDPEPWTLCRSVVQLRRNIFWCCYVIDASYSLNSGSPERFPDDYITVGLPALPSIEFGDDIGEIDAENETRRIGFLIEQAKLWRIVKKIRRCGQTSNKTSESYCEGANLYRPSADQDSYSRYGEIKTPTSTSSPSPWVWRADSARRILDVELAQWQMDLPQHLRFDFSLTRKDEPCPFAVRVNGLGAMLQVIFNEVLILLHHPFLILADSQSRSRQEPAAQIPARNSKSRSSTSSTKSSRSRSSSSSSKPSPSSSLLNTVDENAVGASPSLPPFLNTCTKAAEAITFLINHLLNSTPEWLVCHNEVDSALHIAERVHTLNVVMAASGSTPGTPLSGSSYAAQVDGQQAKIQLKRTKAFRKTIKELDQFTMSGGCRPDLLTKQQIARGSARERLMRSMKQMLATKRGPNYYRLPRNPPEEDSHLSSSLPESDGRVENGAGQDHLEMRLSFVDERIWIRYYNIRIKGGVESKNGAESWLEILHQITPPANPVIDSDEEDIDTLGYPPSEDMPLFPLEENDPYSNDYNQPRAPKRPGGAKGNKKDQPAEPMNPPQLSKVALMEFFSSSNPPGVDSLSGMTGGSTYYQFEDKESPVSAGPGFNTSMYYPGQYAPHERIESTVSLDHPSQTQVQSTDIFQAEHQLQQQHHSFHSSSPYPTSPFEQQRQQQSPYPNFGLQSSSVVGFDPTNPSFSSSESPNLTTATEAISLNIMSVSTPLPLQSPITFDGGPFLNLLQQHIPHSQVLEHPSSTSSMSFQQHSLDPSLNGMHQTVRPFYGMPMGGFITPSLESLPLVNRAVPVHQPSDAQQANFLPSTPPHQGQSRSWSLDGQRGSGTSYDAKSEPASPAIPSLGSSIPASPLPQSSLRMMLSPTSDALQSISNRLSSWDGLSGPKPDTQIDYPCVSSSTLFQSATASLDQHGGGNSHYPSGWSSASSTSEMMTGNSTPASTALSDGAGVYVSDLSSGPGTSGADLMDGIEAVTSSTSSPSILSGCNSSQHQQHRHLISAVPEAPFGDFAISNPDDPVRFYRHPKEGGSEMNVEVGLGDNRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3F5</accession>
    <name>A0A9P6N3F5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_000817</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000118">
        <property type="protein sequence ID" value="KAG0022186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3F5"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="90"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0022186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="139" mass="16014" checksum="7B72C298750ADC08" modified="2023-09-13" version="1">MVQTFQLEKSTETLITSRKTISEKQREFILLHINNGRRPSVQVELIQLISENKSIQHQWSVGMEAYHQVYVVEAAAAAAEATAKANAELKSTLENDVRVLKYQIANLKRQLDAVASRRKRMLADAEEHRIIMRRNKTRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3F6</accession>
    <name>A0A9P6N3F6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">polynucleotide adenylyltransferase</fullName>
            <ecNumber evidence="5">2.7.7.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BGZ80_011675</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DNA polymerase type-B-like family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.19" evidence="5"/>
    <dbReference type="EMBL" id="JAAAID010000097">
        <property type="protein sequence ID" value="KAG0022599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3F6"/>
    <dbReference type="OrthoDB" id="2274644at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990817">
        <property type="term" value="F:poly(A) RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010605">
        <property type="term" value="P:negative regulation of macromolecule metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031123">
        <property type="term" value="P:RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05402">
        <property type="entry name" value="NT_PAP_TUTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054708">
        <property type="entry name" value="MTPAP-like_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002058">
        <property type="entry name" value="PAP_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12271">
        <property type="entry name" value="POLY A POLYMERASE CID PAP -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12271:SF40">
        <property type="entry name" value="POLY(A) RNA POLYMERASE GLD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22600">
        <property type="entry name" value="MTPAP-like_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03828">
        <property type="entry name" value="PAP_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81631">
        <property type="entry name" value="PAP/OAS1 substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Poly(A) RNA polymerase mitochondrial-like central palm" evidence="11">
        <location>
            <begin position="373"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="domain" description="PAP-associated" evidence="10">
        <location>
            <begin position="634"/>
            <end position="691"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF22600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0022599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="730" mass="82826" checksum="BE48EC1851D5F262" modified="2023-09-13" version="1">MSAHIANIPVALSSAEISAQIARDDGDFVGVLFDTILYERACYRLYELKKYDFPLRYDELSHDFTIAYRLCLDPKFLANRHTAAFSHLILHSKVMTPKGIRKWVLDHGGLYELFPADDTSFMDGGGDIEELDDDDFSDYDEVEQKMSPVRKNIGYNGPILSRRTQSYHNGPTSEGQSHRDGMANSYFAVYKHTQDMVAVIIAHLRKRLWHNNGSGGEIVDIRNMGVDGKGGQADKTTGETTDQPIPDVKGVKKYTRRFNGKRKRANYDKRMKDGATGFWREFLPRDPPTDYSDSEFEDQGNDVDTLTREGVDVAIEKLARVSLENFKGNPKRKIQWLPLQRSEVLYDSAGPNRELRLIELPTEDDDPTFYGRLTRDLLTKYKKLQPPAELIERHKMLKGILEGVISSTFPGEDLKVEAYGSFVSGLLMGNSDADFCINGPNIHDHDQLNDMNYLADILRTRGKMQNVIAIPDAMVPIVKFLDPQTNMECDLNTGNNLGVINSDLIRIYTTLDERVKPFLFMIKAICKAQGINDSKAGYLSSYAITWMGIVFLQQEGASGSPTWGWSPKAVLPKLQQQPFERMREITLRLNHNTKNVVTSNTSLINSNKSDMVHCRYDDNKDGKHTGVGHVNTKSLARLVIEFFEFFSRRFNFIETTIHAGRGQIAKKTNRELHQENSRLPAFRVVDPFLHHRNITGTCRGESLARVWRAFDHSYRMLSAGDLEGAMVNVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3P9</accession>
    <name>A0A9P6N3P9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">CDP-diacylglycerol--serine O-phosphatidyltransferase</fullName>
            <ecNumber evidence="5">2.7.8.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Phosphatidylserine synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="primary">CHO1</name>
        <name evidence="20" type="ORF">BGZ80_000170</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a CDP-1,2-diacyl-sn-glycerol + L-serine = a 1,2-diacyl-sn-glycero-3-phospho-L-serine + CMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16913"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57262"/>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="EC" id="2.7.8.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="17">Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 1/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 18">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.8" evidence="5"/>
    <dbReference type="EMBL" id="JAAAID010000103">
        <property type="protein sequence ID" value="KAG0022468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3P9"/>
    <dbReference type="OrthoDB" id="448573at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003882">
        <property type="term" value="F:CDP-diacylglycerol-serine O-phosphatidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006659">
        <property type="term" value="P:phosphatidylserine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1760:FF:000022">
        <property type="entry name" value="CDP-diacylglycerol--serine O-phosphatidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050324">
        <property type="entry name" value="CDP-alcohol_PTase-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004533">
        <property type="entry name" value="CDP-diaglyc--ser_O-PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048254">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00473">
        <property type="entry name" value="pssA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14269">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14269:SF61">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--SERINE O-PHOSPHATIDYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="13 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="15" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 18" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 19" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="172"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="214"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00032361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00060701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAG0022468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="240" mass="26307" checksum="80339ED56A8357CF" modified="2023-09-13" version="1">MSQRPKNIRQGTSEMEIPTTLTKKQFQQVRNLTKDDGHFNLVRNFHLADVITLCNGASGVLSIFSNLRYLIDHDPYYLKLAMWCIPLGFTFDVLDGRVARWRKTSSILGQELDSLADAISFGVAPAVLGFVLGLQSFLDTVVLTCFVCCGIARLARYNATVAILPHDKSGKVSYFEGTPIPTSLILVAILAYLSHIGQVGDQLPGGLIEIVPGYSFHAMVAMFGLNGTLMVSKSLKIPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3U4</accession>
    <name>A0A9P6N3U4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BGZ80_010629</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000076">
        <property type="protein sequence ID" value="KAG0023009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N3U4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="318"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="348"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="408"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="438"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="481"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="22"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0023009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="620" mass="67453" checksum="6C42DF4A55C064C3" modified="2023-09-13" version="1">MNSQSQTPSGGSVLSHPLLENSDGQTSSMIPATSTTTVMSTTTTLSSSETANTALNFSPPTSLAMLSSEDTKSISPITSTTTISTSSATPPLSTAIESVSATTTPKHLLNLPVEILEEIVFCLPSPRNFVRCCRQIYELSTSPSVRAKYLWLLHGPDQVLARKVVELHKLTSSILTSPVALLLIAMGATHRDSEEFIFRWACSKGYLDVVRQLLKSEPKIDMRFRSDWFLREAAKNGRQSVVTFLLQQPDYVPSESGLDKAFEAAYEQSHCSTVKALFDYAEAKGAQMEQSPVIFQSIVPSTKRAKRIMAAGLHIQKDADKALRYAVRGNDVEMVKLLIDYEADVHAFNEEAIMVAAHKGHVEILKLLIQAGADFETKAGAPLRQAAEGGHAEAVRILCESGADTMWGGCSALRTAASQGFDTIIATLLDHGANVNIHEGTPLQLACQHGHEAAVRVLLRYGANHRLDDGAAYKLALEGNHENIKALLVQAETTMRAKERELDRIMQQQGPMMMAQHQQMQQNPWYSSHPRMLSENRVGASAFTPNPSFVSASSAAAAAGGFFTGSIGGLDSMSRGYKRFYSQMSNPLSAADLFRSGSICGLVALDDEIRSRQRSESNRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N3W0</accession>
    <name>A0A9P6N3W0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="3">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BGZ80_007847</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="3"/>
    <dbReference type="EMBL" id="JAAAID010000041">
        <property type="protein sequence ID" value="KAG0023825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010992">
        <property type="term" value="P:ubiquitin recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01927">
        <property type="entry name" value="cyclophilin_WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000003">
        <property type="entry name" value="Peptidylprolyl isomerase domain and WD repeat-containing 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000450">
        <property type="entry name" value="Peptidylprolyl isomerase domain and WD-repeat protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.80">
        <property type="entry name" value="E3 ubiquitin-protein ligase SopA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056251">
        <property type="entry name" value="Arm_rpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19849">
        <property type="entry name" value="PHOSPHOLIPASE A-2-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19849:SF0">
        <property type="entry name" value="PHOSPHOLIPASE A-2-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23948">
        <property type="entry name" value="ARM_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25173">
        <property type="entry name" value="Beta-prop_WDR3_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="20"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141571">
        <property type="entry name" value="Pentapeptide repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="17"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="15"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0697">Rotamase</keyword>
    <keyword evidence="5 9" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="136"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="282"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="11">
        <location>
            <begin position="482"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="1860"/>
            <end position="1901"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="1902"/>
            <end position="1943"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="1944"/>
            <end position="1985"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="1986"/>
            <end position="2027"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="2028"/>
            <end position="2069"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="2070"/>
            <end position="2111"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="2112"/>
            <end position="2153"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="2154"/>
            <end position="2195"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="2196"/>
            <end position="2237"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="2238"/>
            <end position="2279"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="2280"/>
            <end position="2321"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="2322"/>
            <end position="2363"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="2364"/>
            <end position="2405"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="2406"/>
            <end position="2447"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="2448"/>
            <end position="2489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="447"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="37"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0023825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="2557" mass="285361" checksum="D22245C9A0668385" modified="2023-09-13" version="1">MPAEKDHKDSDEQENDSATLGKRPHEPEAEPAPAQDSGMSTLPSSTPHYSDDDIGPMPATAADEVQAKKRRKPLPHEQLYISRLPSAEMYEKSYMHRDAINFVAVTKTDFIITTSVDGFLKFWKKTDQGIEFVKQYRSHLALISGISVSDDGLLLATISLDKTLKVYDVINFDMINVIKLDFVPSNVYWIHRRGEAQAKAAVSDSESPAIHVFDGRGEGKPMFTITKLHSGPVTTMAFNDKYNCVVSADDKGALEYWVPDEEHELPKTVAFEYKSETDLYEFKKCKSAATSITFSQDFEKFVTMSAKDRQVRVWKTRTGKMIRKYDESLDVINEMQQTGQKMYKLDDMEFGRRLAGERVLTKSTQQGCMNAVFDESGNFLIYPTIFGIKIVNMHSNKVVRLIGKSEPQRFAMVASDNAVIKESELRDPSLFCTAHTRNRFYIFTEREPDQGPSHKADRDVFNEKPSREEQTIATAQHTKTKLGTTAILRTTMGDIQIKLFPELVPKTVENFVTHSRNGYYDNVIFHRVIKSFMLQTGDPLGDGTGGTSIWGKEFEDEFHHDLKHDRPYTVSMANAGPGTNGSQFFITTVPTPWLDNKHTVFGRAVTGMDVIHNIENLKTDKTDKPYEEVKIMNIEIRYNKRTRNIDMLRNPFSSRTIGLSSEDALELANKYLGNARKEGDTAKALELCGDAESLLKEAENIFVSKKVKDPVLSEGIANAYHEHERLLKDLGRYDEAMRSHSKAEEWGYVHVISQSTVPSQPVAPNVAAAVSQDISETDHPLHSTPAKVAQIQQKIFDQNITPPVTKYTLPEVNERITSAAQLAYCLSLLYPPMIPKEELSQSEYDWLQTRVVDLDEQERLQTMATDLVRAFVQEEPKKPNVVAEIVSLAAVFGQDDFRKLLQTFVNGISQSVLLDVHLLNGLAQLIRNATQGYIDADDLVKILELLSARLKDTHKQSTRHTYQLALAISQVLDSMVDSQVEGLSREQLRQPLSDYLEGLQQSPDPYLIYQAAYAYQALQYIPDDETILQSMMRRTGKVVQGISGVVSAAKALDLVGFIEGLQSVQQSLDGTEKAIGYVSDAYSNALALAENGQELLASLKDGFSSKLKGSWYPALRGLDRLAQEGQFADFEKLVREAPCRHDPAFRWGVCQRLGKIAANTIWDLKTRKCAIDFLRRLYKEDVDKDQQVNIKQWILYILSQLAESFKEIIEDSTKELLQEVQPNSSSAEGTQYRGFGNDNPVLHPVIFTPQSIESLLLDRVQNKPDVETPLHQLKLERLKGRGGDVYISPRAKATPRATDDFDLAAKVQEFLASDRKVFLVLGDSGAGKSTFNRALEISLWDSYKVDGRIPLFIHLPAIEKPERDLVAERLRQANFTESQILEMKLHREFILICDGYDESQQSQNLYMSNQLNQPSGWRAQMVISCRTEYNGVEYKDCFQPTDRNSGKSTGEYQEAIISPFTKEQIQDYIGQYVSLQNPQWGLDDYLQAFKQIPNLQDLVKNPFLLKISLEVLPRLLRTNSSFSSTRITRLQLYDEFVTLWINRGKVRLMEMELNPSDKETFKQMADTGFRQCGISYMKELVTAIYEHQNGNPVVNYSVHSDRRTWKEAFFGESDGNHLLREVIPLTRNGDQYRFIHKSLLEYGLALAVFEPGKLNEDTEATPSVSRRGSASSVLSFEDHSLTERAATADDRSLEDSPLWKRNLVGERSILQFLTERVQQEPIFKTQLRSMIERSKTDKAARIAAANAITILVRAGVQLNSADLRNIKIPGADLSFGMFDSARLEGADLRKVNFRNVWMSQANLRGAQMKGVQFGELPFLQEDSRVACCTYSPDGKTYAAGLDSGAIILYETSSWNRIQKMEGHTDNVNSLSFSPTSDKIASGSSDSTVRLWDVDTDECIHTLEGHSGKVYSVMYSPKGDLIASGSFDSTVRLWDVDTGECVHTLQGHNDKVRSVTYSPKGDQIASGSDDKSARLWNADTGECVHVLEGHSSYVRIVVYSPKGDQIASGSDDSTVRLWDVDTSECVHILQGHSNYVLIVAYSPKGDRIASGGEDSTVRLWDVGTGECVHALEGHSNWVRSVVYSPNGDQIASGSDDSTVRLWDADSGECINILQGHCNYVVSVAYSPKGDRIASGSYDETVRLWNVDTDECVHTSQSHSGSVNCVVYSPKGNWIVSGSSDSTLRLWDADTGECVHTLRGHTDWVHCVACSPKGDQIASGGDDTTVRLWDVHTGECVLILQGHSNYIVCVMYSPKGDQVASGSSDSTIRLWDVDTGKLVHALQRHDDWVRSVVYSPKGDQIASGGDDSTVRLWNVDTGECVRTLEGHGSYVRSVAYSPKGDQIASGSDDTTVRLWDVDTGECVRTLEGHCGDINVVVYSPNGGQIASGSSDSAVRLWAVGTGECVHTLEGHSDYVFSVVYSPKGDRIASGSSDSTVRLWDVDTGECVHALRGHSAGLNSVVYSPNGNRIASGGNDKTVKLWNVETSHCLVTGSSEEVKHKAVLCWSSSHEVLTVYDLSFEDVQDIGRLNQGLLIQREALAPKCLPSQGSVENSNFLRND</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-04-02" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4D8</accession>
    <name>A0A9P6N4D8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rho-GAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_010834</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000008">
        <property type="protein sequence ID" value="KAG0024677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rho-GAP" evidence="2">
        <location>
            <begin position="78"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="313"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="446"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="486"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="579"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="678"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="756"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="873"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="924"/>
            <end position="945"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="958"/>
            <end position="1043"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1077"/>
            <end position="1152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1228"/>
            <end position="1341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1403"/>
            <end position="1422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="486"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="509"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="582"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="682"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="714"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="760"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="797"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="873"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="977"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="993"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1008"/>
            <end position="1035"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1079"/>
            <end position="1091"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1099"/>
            <end position="1129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1138"/>
            <end position="1148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1246"/>
            <end position="1261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1284"/>
            <end position="1293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1311"/>
            <end position="1323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1403"/>
            <end position="1416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0024677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1422" mass="154841" checksum="AA3A64F4ED1D9B0C" modified="2023-09-13" version="1">MPIRPTSSAKNLRDQFKGSNIGANMSSIDSPTSGISRSKTLEPAIRHSKSGLLRTSSGGGSLRRVKSFQKKGKDSLAATLDLSMEVTLVIVKRCVKEIRLTCKGILRQLKMAHSNEIILQTIRIILDDEATTELSPLHQLDIHLVAHAMKWAIRHSEEILVTYEDYQNLYVNQDRNFSSFVRDIPPTNRAILLDLFSLCADVTLLAHLNDMTPVIVAKSLSLSIMDGPDREHTTFDASYQQRSLSAAACEDLLRAFLRIKTTHDLAKIDQEDEVDENRYICNETRVLKSARLRSHEVVLPSHIDISVPSSAGSTLSGSAGWPTPAGPLSASTPRNYNGNNAGYFDITPQSGSPISHAGGMYGASLSRSQSIAKSSDPALRAMSPSPYNGDDITEYEELMQDQSHLRRLRQERNSFLRPAESIRAESIRRRSVGDMDSIYMMSVEPAAPEDGYDSDPEVCHAQEADEDTRESLIPDFADGLGWDFNKQVQADPSQSPSLDNYQSQPLNKNGVNRSNSASSNASGLGVGGPSHMGSPRSIRDLSKQQLAALRLQQLQDQRQTEFQSFHHALSQQDLPARDLSYVSPSQGSVNSTTSLSRAPSNRAPKPTPSSFNTPRRSRRNSALRRSVTIDPNSIYGRSHRRLESIHADLLARELAHQADRYIVAEDIRAELLRVQNDHQEPSRASSEFSLQMSPQDLERPKSRRPSLFSIGEQHPSSPSQKQPTSVNNSRSFEVISRPKDVEVSVIFTPIASATSPSADIKSKFHESFPERPASPPAAPKRSLTSSGIGRSTPPLLQQSSSFSGISTATSQLSSSESKPKSSGFIRALSSKLRPKQSDDQLKQSKANAQITEAPAAAPAVSFEPPRLELNFFGDSLGSSDLSPSSEHEGQLPPTSAPALMLQTDSGVINLENWKHEAQLSLPIPLVSGSGQQDDRPTGFTGARRSSAFVIGSISDSIREQRRITKKGSSPALTAFRTTTSSKSNGTVSTSSKADVEPQARSSDKKGTISDSSFPTTDDSGSAEESTRGSAESSIPKTGASEKEYRFSTATLLKDGKLYHQLQWEEFSNLGFKSDIMTEPEQTMSGVHQLRTSQEDPRKQSTSATAASMSVNQRQQNNQMRISVSSSRNPSVDLPGQLGQASRTSTQEPGPSLAQKAVALRVAQESFIALANDSQALEALKEKSASGNRQPTIISSGSFAKDSTLPILDHFSRPPVITSKATLLHQKQQSLEITSMDGEEQDKLQRSMSAKSSLTSSATEAAHLPDSKTMKQLGPVAVGGGGHGSSVSLSSGPRPGKPASIKAPYSPEIKPKGARRFFGKKSKKGSNAASTFPSSSNGGRKRRMFPVGVRRQDVMTKTIESMDEVFPWMCIEHMAGQESGWVMLEPVQDGAVGWVMVDKLEDDMKAPNTRPHEENLREQLQVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4I9</accession>
    <name>A0A9P6N4I9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Snf2 family helicase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BGZ80_008918</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF2/RAD54 helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000050">
        <property type="protein sequence ID" value="KAG0023593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18007">
        <property type="entry name" value="DEXHc_ATRX-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044574">
        <property type="entry name" value="ARIP4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056026">
        <property type="entry name" value="DUF7607"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45797:SF1">
        <property type="entry name" value="HELICASE ARIP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45797">
        <property type="entry name" value="RAD54-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24580">
        <property type="entry name" value="DUF7607"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07647">
        <property type="entry name" value="SAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00454">
        <property type="entry name" value="SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50105">
        <property type="entry name" value="SAM_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAM" evidence="10">
        <location>
            <begin position="10"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="11">
        <location>
            <begin position="1287"/>
            <end position="1480"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="12">
        <location>
            <begin position="1638"/>
            <end position="1817"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="194"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="334"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="523"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="651"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1027"/>
            <end position="1201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1899"/>
            <end position="1926"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="2096"/>
            <end position="2151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="230"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="287"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="534"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="685"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="695"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="777"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="830"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="925"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1028"/>
            <end position="1061"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="1084"/>
            <end position="1101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="1139"/>
            <end position="1153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1915"/>
            <end position="1926"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="2096"/>
            <end position="2110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0023593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="2151" mass="242758" checksum="D1C48B2548029295" modified="2023-09-13" version="1">MDLPVDPLTWGTDDVCKWLKLEFNLGESVLKQFHENDIDGPVLLGDVDHEALKHDLGITSFGQRSKILAKVRMLREPKLNKQDPNNVHLGSPLPAAVMNLKGLGLGLGDYSGIVHNNASPQTYYSDEDKAITLLEKPLRMWEENDKEWIREKSTSSEVGRHDWIDHSEEYNIIMDSTNHLDEDDEPLASRVDRKKRLSVTSPTTALPRNGGFRDHSIQSQPSTGKPISKRITPILITSPISSRLPDQGIRSSAPINATGVAGGPRGIVPTPIATSQPPTPQDLEPALQTTNRSNSASPLTDGSKFANTTGASAKRQQYLTRLGLSLRDIFNMDSPSVDNDSDSEDEWSMTCPQSQRKSIPKGHQMIIQRNMKRILRERPVFEIPDHVIYAPIRRRDRDVPVKVISNMGSGSDSSTYGIYLQQKIKVEWTTLMTGTIHVHFNLVRKSTWDTMLKSKSGKSASLRLDLNSQEYDITSIDFRAITGRTEYKMPVPSKSDDPIYPLYGESDASAYTTDEELYREVAKEEKERSKKRSTSNMAAATKTSVPADTVKELTTKYVTEQKELWDRVSRPTMEKQRSRLYQELLRDSGNVSPLDKMRALHVQLEERLKSIMLAIQETQYKNEKEVRKACQAADRTLAQINFSQWKLDLLSGPAPLPQPEDDQSANSIPETHSRDKTGSSVPSARHPEQSKEETDYISDDEFMIEYEDEEDDEDEDEEEKRQQELDAAFIDDSGMVIGFEPSDLDGYSSGNMDEDVIMDDSNDHSNTLAPIFTSHKNQQKNKNKGKYKKQGKTKKPKNGAGLSKKQRREKMKGGRVLNEASARILSPTTKKLDDVRKGKATDPGPAAHGESRTSRAGSTTAVIDLEDPEPLKSNLATVDRSPAAQTSSKSPISKPENGFKDEDTSQGADEASLPVAGSSEQDSRPPSPSPPPKTLPMKSPDWRKILTDDEDIAKMFRTIRKNMSLGKRVKDKEPYISAWQEYAEWMELDCGDSISLREFLKWKSEGNSTEVYRQKAKEAAAIQAAVACREKKEKEEREARERKERAEAERRAREMADREKEESEEQAIQPDTITIDSDTPKEYDDNDDDDDDDDDDDEGSVMEEGRVNLQSGLSHSNEVRKSSRGRSGGSRQQKKDDGLDSPEEILDISDEAETSTQKVPALNFKKRPRPVRNKFGDPSSESSNPEEEQINPSKHAPRRRVKRAMLDEAEEVLRLRKDAVKNELELKKRIAEQEMRAKIRGSMGPLREGEVLINPGHKKTERGVAIPAFLATKLKPHQIDGIRFLWKNIVMFDGGCILAHSMGLGKTFQVVAFLYVLLREIQAGNKDIPEKLQEGRVLLLMPPIVLDNWDNEFLKWIPEEELHVVNVRRLSIKVKTAQSRILRIEKWYKEGGVFLLGYAMFRELCIGTVSQSVKDQYKMLLQEGPSLIIADEGHTLKSATAKIGVASKHLKSTARVILTGYPLQNRLEEYWCMVDFVRPNFLGDIATFRHNYIRPISDGLYPDSSMIEKKFSSKKLKVLTELIKNFVLRKDQSVLRASLPKKVEFVISCRLSTLQYFLYTSFLPTLGTAPKDLLSNGHILLTICNHPAAFKATLDLTAKKQEKAKAATNNSNDDLKAKSTAELPLVASKEDFINPGEETEDEVAEKEIVDVLSQNKEVASNHWSGSSFIQEKNVNDVSHGYKVKVLLDILTECRNIREKVLVFTRSIPTLATEHNFRSMKLDGDTPIAAGSQGVNLVSASRVVIFDVGWNPSYDEQAIARAFRYGQERKVFVYRLQTFGTWEDKLYKTNLHKLGLSNRVVDKKNIAKTFSKTEMKSYFEPPPETSPIWASDETVEAFFAKPDTEDLVLRKVIQNNREQISLIVPQSELVREKDSDLTEADMIEIQSMIDAEQRRIEAFGQQQQQPNVAGLPQPTPQQHYQVQQQQQRQVPQQQQHYQVQQQQQYYQVQQQQQPYQPQQHQLHYQVQQQRSHPVEQVQQQYMVQYLPTTDGQGSAIQSMQIAQVLKAALDMQLLKNMSPNQSTQSNQTSVDATQALVQTQIHQPPPSRQELHWQGESREDVLERTQRETLASSRARLLQQHHGNEGVSANTTIQMPAGTSSTSTTASAIPYTTPPSVPSINSMLQPIPDLPQVKPISMSMQQSPNQHAHDKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6N4V8</accession>
    <name>A0A9P6N4V8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 14">Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase</fullName>
            <ecNumber evidence="4 14">4.2.1.134</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BGZ80_001333</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 14">
            <text>a very-long-chain (3R)-3-hydroxyacyl-CoA = a very-long-chain (2E)-enoyl-CoA + H2O</text>
            <dbReference type="Rhea" id="RHEA:45812"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:83728"/>
            <dbReference type="ChEBI" id="CHEBI:85440"/>
            <dbReference type="EC" id="4.2.1.134"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 14">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="14">Endoplasmic reticulum membrane</location>
            <topology evidence="14">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the very long-chain fatty acids dehydratase HACD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.134" evidence="4 14"/>
    <dbReference type="EMBL" id="JAAAID010000013">
        <property type="protein sequence ID" value="KAG0024576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6N4V8"/>
    <dbReference type="OrthoDB" id="46988at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102158">
        <property type="term" value="F:very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030497">
        <property type="term" value="P:fatty acid elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030148">
        <property type="term" value="P:sphingolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042761">
        <property type="term" value="P:very long-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007482">
        <property type="entry name" value="Tyr_Pase-like_PTPLA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11035">
        <property type="entry name" value="VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11035:SF3">
        <property type="entry name" value="VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04387">
        <property type="entry name" value="PTPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="11 14" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="7 14" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5 14" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="9 14" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="153"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="190"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00036671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU363109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0024576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="230" mass="25852" checksum="3D544EE1ED1F091C" modified="2023-09-13" version="1">MAKTTSQTPAASSGKKAPKPVNPIINLYLIAYNWASFAAWGYVLLQTSKTLLETGNDYTKVYAVVGDQLVWVQTAAILEVFHALFGLVKSPVGTTAIQVASRLLLVWGVCTLFPVPEVRSYWAFTTMTIAWSITECVRYAYYALNLVNSGPAWLLWCRYTFFYILYPVGAGSEAIEIYQSLPFAHTIHPGYYYFLIAMICTYPPGFFVMYTHMIGQRKRYLGPAKAKKSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SR94</accession>
    <name>A0A9P6SR94_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_008181</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004367">
        <property type="protein sequence ID" value="KAF9993322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SR94"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAF9993322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="97" mass="11449" checksum="8CFF7AEDF99A1B41" modified="2023-09-13" version="1" fragment="single">LEMSFRFEESEQDLQPLVFRRLSSLVLIEKFDISRHDIGAETRQLDMRLVSGLEQLSHWKNIKILSVWGSEQSMEEIDVRWVIENWPRLGAVHGELN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SRU9</accession>
    <name>A0A9P6SRU9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NAC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_007737</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010004005">
        <property type="protein sequence ID" value="KAF9994718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SRU9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9994718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="272" mass="31600" checksum="BF8C873B43D7C970" modified="2023-09-13" version="1" fragment="single">MNAIKTNETDVYDMHSLSTFLPCAIDNVTEDDIAGAGLAEDVTGYAIDEDDIPLDDNPEDSTSEAARMREEDERTINHFNTLSIVLQRQFEGPAPWIDLPPVIATPLVVQTGSRRTISYEPRVFLLDEANYVNWIQEDGRYRFFTWRKTEHKETEENGTSRFEWWEKWICHRSGKPENKSKKSETDKTGQTKSRFSKDSMKTECEAAIFVHKFKSAHPPDPSYDAKGSRRRVRILYFYKHTGHTLGATEDLQHQYLSEEIKCHEWQGRFIQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6STB6</accession>
    <name>A0A9P6STB6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_006696</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010003310">
        <property type="protein sequence ID" value="KAF9998913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6STB6"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAF9998913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="72" mass="6759" checksum="91197C58392A6C3F" modified="2023-09-13" version="1" fragment="single">ITQASEGMTPLVGLLNCAAANSTTGSNSTTGTNSTGSGSNTSPAAGTSASFQVNVPYVLSVAAVGLAALAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SVC9</accession>
    <name>A0A9P6SVC9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">IPT/TIG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_005084</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002525">
        <property type="protein sequence ID" value="KAG0006946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SVC9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="399"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="439"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="456"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="542"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="557"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="581"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="602"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="630"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="684"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="715"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="730"/>
            <end position="740"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0006946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="740" mass="81627" checksum="F5908303B6B3DDC2" modified="2023-09-13" version="1">MNDSYAEANSIVQSAAHLSLDATVVTIPNSTEHSLSREVDNNTEHRSFSGELAPAACKPDEKLDNFDVQLSPSPGQGSIERQNEPNHPQLDHSQSRQEHNNPQLTDNHHTSSRDAWADQGHFPLILGEISLKSIPVRGGSRVVLSGVNFREGVEVVFECPKLGKGIEARVVKPRVLKSTEMDIITPNLLDWWVASNKEQPCKQLELSVSLTCAGERSEEDINTSFEMFAFDDSESELLQIIVELHRQQILTSIKSSGSLDSETERTARQRTMTLLQLERPESVSKTEHLALSVIYMLCDGRDQISSEGMDLIKATTDDGHEMLHLAVIQGQITLVREIARHSLCWFQNRPIISDSEVFVKNCNGETGIDFAKALGQSEIEQVLRETLEEANEFKKSILKALPQPPTPPISIHSGPGAGNAESPHMYTSSPIPSHALDRPLPPTPPSAPPQELRYSPNRTTSYFSVPPSGNSMVESPNQYPYPPAQSIHASPHAVYENPSPYTNSNDPIRMPSPGQHYPPYNQHNIPPPLHYDPSSAYGANPHNISPPQENSMPIPRPTGSPQGEQPSPPQSQTTVAPPLPPRHKVTRVNRPKQFTIPAPDVPQTQGQPPPTSHTHAQSPHQQRDQYPPVLAAPPPLPVPLPQPMPMPAHQYPALLPMPTHQPPPSVHQPPSSMPMHHHPSHMPVYPPVPISTYQPPSPMPSHQYPGSIPMPAPSHQYQPTVPNQDSYGSKPDDHIKVYVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SVW9</accession>
    <name>A0A9P6SVW9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Inositol-1-monophosphatase</fullName>
            <ecNumber evidence="8">3.1.3.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_004433</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>a myo-inositol phosphate + H2O = myo-inositol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:24056"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:84139"/>
            <dbReference type="EC" id="3.1.3.25"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 7 8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="8">Polyol metabolism; myo-inositol biosynthesis; myo-inositol from D-glucose 6-phosphate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the inositol monophosphatase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.25" evidence="8"/>
    <dbReference type="EMBL" id="JAAAID010002261">
        <property type="protein sequence ID" value="KAG0007628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SVW9"/>
    <dbReference type="OrthoDB" id="10254945at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008934">
        <property type="term" value="F:inositol monophosphate 1-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006020">
        <property type="term" value="P:inositol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01639">
        <property type="entry name" value="IMPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.540.10:FF:000004">
        <property type="entry name" value="Inositol-1-monophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.540.10">
        <property type="entry name" value="Fructose-1,6-Bisphosphatase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033942">
        <property type="entry name" value="IMPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020583">
        <property type="entry name" value="Inositol_monoP_metal-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020550">
        <property type="entry name" value="Inositol_monophosphatase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20854">
        <property type="entry name" value="INOSITOL MONOPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20854:SF4">
        <property type="entry name" value="INOSITOL-1-MONOPHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00377">
        <property type="entry name" value="IMPHPHTASES"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56655">
        <property type="entry name" value="Carbohydrate phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00629">
        <property type="entry name" value="IMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00630">
        <property type="entry name" value="IMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 7 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="7">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="256"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR600760-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0007628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="331" mass="35803" checksum="612C855C42A7E7EC" modified="2023-09-13" version="1">MSYTAADLESYLQFAIHLAKLAGPVILEGFNSRFSPERSALLVKKGNTADLVTEWDQKVEKMVRAEIAEKMKGHLFIGEETVAAGEECGLTDAPTWIVDPIDGTTNFVHGFPFVTISVGLAINQEPVVGVIYNPILNQLFTAAKGQGAYLSKIDEDPRSHGKRLPLSYPHRPLPLPSLSMALVAGEYGSDRKADVIDPKVKSMRNLSAREPSSLAPGRAVGHAHGIRCLGSATANLMAVAQGQMDVYWEVGCWEWDVCAGIIIVREAGGIVVDGCGRQVTDGQLLTGRRFLVVRACCGDDGDTSPEASLAAQKKIVEEVWSVVEDFDLPRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SW09</accession>
    <name>A0A9P6SW09_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_004514</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002297">
        <property type="protein sequence ID" value="KAG0007555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SW09"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027948">
        <property type="entry name" value="DUF4436"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14494">
        <property type="entry name" value="DUF4436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="121"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="253"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="253"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0007555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="300" mass="33784" checksum="BC211C27FB2C4BDB" modified="2023-09-13" version="1" fragment="single">EKAIIPDQSLKSVLKESRTLGDYIRVVGSVASVDFEDKNFRVHFKFTPHGTLARDDGVLTTAILLLGDPCQQGKGAAAQDPSLTFLGMLQSVELIPTIRLSNDDLYKISIENFTRRSPTTIGFSLFIVMIMWALSFAIGIIAIQVIRKYRVTDERALTLGITTLFALPALREAQPGIPAIGCAADVLGRPFYDCQVKRKRMPFMTSHRHIPSDDVRSLKPNPNSRFYGEGGYEYHHISKDRRYYSEDLRHPGYQHQMQSPQQQQVQERMQGQAQGQAQGYKPGARSAISTRSINRRLRSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SW24</accession>
    <name>A0A9P6SW24_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RNA polymerase II degradation factor 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">BGZ80_004175</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
            <location evidence="3">Telomere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DEF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010002156">
        <property type="protein sequence ID" value="KAG0007833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SW24"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000781">
        <property type="term" value="C:chromosome, telomeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="term" value="C:nucleus"/>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14368">
        <property type="entry name" value="CUE_DEF1_like"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="CUE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041803">
        <property type="entry name" value="DEF1_CUE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051833">
        <property type="entry name" value="TC-DDR_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16308:SF13">
        <property type="entry name" value="PROTEIN LINGERER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16308">
        <property type="entry name" value="UBIQUITIN ASSOCIATED PROTEIN 2-LIKE/LINGERER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02845">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0227">DNA damage</keyword>
    <keyword evidence="14" id="KW-0234">DNA repair</keyword>
    <keyword evidence="13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0779">Telomere</keyword>
    <keyword evidence="11" id="KW-0832">Ubl conjugation</keyword>
    <keyword evidence="10" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="CUE" evidence="17">
        <location>
            <begin position="33"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
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            <begin position="76"/>
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        </location>
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    <feature type="region of interest" description="Disordered" evidence="16">
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            <begin position="171"/>
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        </location>
    </feature>
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    </feature>
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            <begin position="384"/>
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        </location>
    </feature>
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        <location>
            <begin position="444"/>
            <end position="510"/>
        </location>
    </feature>
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            <begin position="604"/>
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        </location>
    </feature>
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            <begin position="685"/>
            <end position="707"/>
        </location>
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            <begin position="14"/>
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        </location>
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            <begin position="123"/>
            <end position="132"/>
        </location>
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            <begin position="138"/>
            <end position="154"/>
        </location>
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        <location>
            <begin position="213"/>
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        </location>
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        </location>
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            <begin position="830"/>
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        </location>
    </feature>
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            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00004574"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00020536"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF02845"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="KAG0007833.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="852" mass="89368" checksum="11A8E866AA105FC9" modified="2023-09-13" version="1">MATLHSSNTHRRSGGKDEPEDLRQLRQQHGGSLATLKELFADWTEEDLLYAIQDAGGDIELTILRISEGYATQWGEVKGKKKASKSKSGSEKQEFRTSNSQRGGFAGRGRGDSSRGGRGGATRGAPRAANGGDRNGRSTKSGSTLVSDQVSNDINDSKTESEIITAVATDFTADTAPTWGDAPTWGDSPAWGDAPSTTNDSSNTADNWSTPITATTTATNDSAGATDTAAAASTSTDSWGSVSASPASAPARKVNTATIPAGSKMSWAKIVKPEPAPKPAVAPAPAPAPAPAPVSAPAPAPAATTPVPTSDDVNVDIPASEPAVVTKPEEPVVEETPEPAPVVPEEEKTVEETIPEPEVVEAVVVEEKIVEEVVVVPEPVAAEPVQAAPIASPPKNATPVGPPGLKPKAAQPRRLHQDAPVVMPSGSSSLQSVGVKFGSFSLNDETETAEPEAQPSQPQQTQPEQPSQQTAAAPQPQQQQQQQPAAYGRQPNAPAGASGYQGAAPAASGLSPAATNATYLKQDPAANYLGHHHPAMGHDAMGSPYGSYMPNPASQLGSFGMGPMATLPNDYAALYGNDLQRAMYYDPASYGQIPVTAANNYQSRDSKYNQDSSSTATTSGASSTGTTQAQQTLQQQQQQQQPYPNMAGGMPYYPYYYMAPNQFPTYQQSGYGQPFVGKNMYPMYQHQQQHSSKPGAANNSPYGSYNSTAGQYSQGGYEDMSGAGIHGMGGLNDPYAKYGNPAMQNFLGNQQQPGTPTSSANNTKGNTGSNTYSGSDKNAASGSQSSNPSQMAGGASLQGQQPGNINQGQQYYQQQMFSNYQYPTHHQGYHPNQHQGQHQGSGRNQQFWGSQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWL4</accession>
    <name>A0A9P6SWL4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">BGZ80_003546</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
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            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001943">
        <property type="protein sequence ID" value="KAG0008354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0008354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="131" mass="14726" checksum="DCB4FA69D75E6C4A" modified="2023-09-13" version="1">MIYSHQDSWTLEGIVQSMPLLGWWYDHVARNILGTVMTSAGGFLHTANQTTGYLQFRAEEVQKMSTEIIEKSSAEIQLRSKEMTAKAQLMVDQAKENVEKKVITAREEVTRMRRMFTGTKAITANGAEVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SWL8</accession>
    <name>A0A9P6SWL8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003223</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
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            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001842">
        <property type="protein sequence ID" value="KAG0008638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="136"/>
            <end position="164"/>
        </location>
    </feature>
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        <location>
            <begin position="268"/>
            <end position="312"/>
        </location>
    </feature>
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        <location>
            <begin position="366"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="282"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="375"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0008638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="389" mass="42228" checksum="3A2DF9DF92D11BDC" modified="2023-09-13" version="1">MPTFNRTLQQRRASSHLPASTLALSSATAAVATPAVSGVATRDGYQSLNRIQSQPLSPQDWQGLVASGAQPVRKALHSFIATSCEKPPETKEEARAVLEEMFQIRANRVRRAIEEGQLATAEALKHKVIQRRESVVEGNVDSKKENARSRAMSAPSEGSAAMDSTTMNNEIDNQSQSWLNLQMTEEPCMGVDNTATEFQQSIPPVGVELFGEQVSTFGLSDDDLMSSFTTFTAKLGDSLLAKSPLYAPRPGGILDNDTQTMEYDHLKQSIPSLSPPSDERSPATSNESPSNSPWMPWVAGHDLVTGPQSQQHDVRLSFGVHQPSQQRAWPSTDRSKCIAPTAALSTAAGICTAISTVFGPALASYDDDHDDGPKLSHKAFRRVRQRDVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SXD4</accession>
    <name>A0A9P6SXD4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_002220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010001541">
        <property type="protein sequence ID" value="KAG0009622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SXD4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0009622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="80" mass="8230" checksum="CAB8E4D6D94EA265" modified="2023-09-13" version="1">MTVIIASSARMIRTPLQAAVRRQYSAAASSASASSASNASAQGSTQVVGHSNQRLAIVSVVSAIAGVDVTYAYFTYFKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZ16</accession>
    <name>A0A9P6SZ16_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase-like protein 21D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">METTL21D</name>
        <name evidence="2" type="ORF">BGZ80_011602</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000953">
        <property type="protein sequence ID" value="KAG0012655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZ16"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF109">
        <property type="entry name" value="RIBOSOMAL LYSINE N-METHYLTRANSFERASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="232"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="273"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0012655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="398" mass="42643" checksum="9BADBE244C451D82" modified="2023-09-13" version="1">MCDEACTQGRTGQQQDQEEIRAGERIDLKDVFLSSREFEFNDYSIDPLEIEEDPTGLLKGGVGSTIWDAAIVLAKYLERSDLLQLTKSKSSASSTPINILELGSGTGIVGLVAARILSTKGYHGSKVVLTDKDNVVPLLQRNVENNASEGIDIESRILDWEAVSGIKAKVIKPATATEDDEEGSTKSIAPSTRLSADVITEELASLATNSTVVTLDSTSSISTTSIAATPITSTTSTSTAPTPTVPATPINADSVTPTNTAMISPTKTNSVIPTDTAPTTSAGTTPAATLANDPTSTASTTTANVQDLLAIEWDTVILSDCIWVPSLYESLIGTINTLIKPGSKTQLVIAFEKRNFSEEMEFFALLGNTFRFKDVKPEDQDPNYQSEDIYLFVCQRRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZG4</accession>
    <name>A0A9P6SZG4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">BRCA1-associated RING domain protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">BARD1</name>
        <name evidence="8" type="ORF">BGZ80_011639</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000961">
        <property type="protein sequence ID" value="KAG0012597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZG4"/>
    <dbReference type="OrthoDB" id="549017at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031099">
        <property type="entry name" value="BRCA1-associated"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13763:SF0">
        <property type="entry name" value="BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13763">
        <property type="entry name" value="BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN BRCA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="BRCT" evidence="7">
        <location>
            <begin position="294"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="459"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="123"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="156"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0012597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="615" mass="68387" checksum="7B8E4F76523006CC" modified="2023-09-13" version="1">MISHDRDRSKRQRILKQEPDSIPQTNIEGDHHSRVAEEDGLDDHQQSKLPPSSGDPPVPTFSQLQRLLSIRRDPSIAPTSTQDNTVPTQHLTFMNELSQPEDKEGSGFVTPRMPSPSLDPLQSFATTYQPIYDFTTQGDASQPQARLSKKRRMQSEAESTGQSDVAKSKSSKLRNGRDTSPSDLQALIEGDVSSRKAESSEVPQRLLEQDTLTAILPNDDGIDASSSEEHEVAQIVESSQPSLDVTMLSLKPNSGGLGRKAQRARRPQESTLNATSLHPDRTPLNDGDITQQQVITCIFTGLNKEQRESFDQNITRVIGAGLLMEHIQDQPFSQSTTHIITNADANILKQEGVALCPRVLKYLHGMLSGPWILSHDWFVDSIDAGVWLPLPQPKYMIQGDTQYGPAPGTQIRREIRIRKSMKLFNSCRMFFYGNFGGPGQKSITKDELLRLVRDGGAETWQRRPASKPLLSTSTRNATADEGSRNQDFFAPSRSFLYVTEDAKPWEVPIDRTAPIIVCDPGSIPSGSIKKGEGGQAGSTKTLTQADLKKHGWLRDYQAVSLMWLLNCISCSIMGAQDIELLYGSKDDMSLSDESPIAEEEIRKLSQAWSRWRNRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6SZL9</accession>
    <name>A0A9P6SZL9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_010768</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000788">
        <property type="protein sequence ID" value="KAG0013907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6SZL9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0013907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="182" mass="21280" checksum="55B4C01F9199C1E2" modified="2023-09-13" version="1">MTSNKHSSNKRLSRSTRSSRNRTHNKYRNHNRNHRIWSSSLSSSWCSIPSVSPSESSLGDWTDAEDSTHELAEDQRLSRLAQFIFIKLKDDETYRRFAWRIAREVKVCRIKDDDNIALAAMTSALPYYTRNTMNLALWIKKNEKTRFTSIKDFIEILSDMEGPDPKPALVYNKCCCQEQQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T076</accession>
    <name>A0A9P6T076_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Triose-phosphate Transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">CAS42_2</name>
        <name evidence="11" type="ORF">BGZ80_009796</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000619">
        <property type="protein sequence ID" value="KAG0015529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T076"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007794">
        <property type="entry name" value="Rib_rcpt_KP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004853">
        <property type="entry name" value="Sugar_P_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05104">
        <property type="entry name" value="Rib_recp_KP_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03151">
        <property type="entry name" value="TPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="258"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="298"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="356"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="384"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="407"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="449"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="488"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="517"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="544"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="domain" description="Sugar phosphate transporter" evidence="9">
        <location>
            <begin position="262"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosome receptor lysine/proline rich" evidence="10">
        <location>
            <begin position="567"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="192"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="579"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="91"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="122"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="156"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="192"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="211"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="588"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="604"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="631"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="666"/>
            <end position="679"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0015529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="685" mass="74815" checksum="5DA969B9131B73E2" modified="2023-09-13" version="1">MTSSSRGLMSAEKGDGGGIRDSFDDESPFLDAHRTFEDEQESFIDATSDSYNAPPPATKNPFDDNGRTHSQQQQHYHKAKNDAAYDSFDSHDDDDDDDELDSADSGSEYTGEEDEGYRAPSDEDDDQEEDEGEEDTQRLLLSSNNARMGGMGMGMRAGETGTGTMLGLDLEQRGNQQDDDYDTLPLSTIDVERIRMKERGHGKGVKDSSTKRRKGHKGTKSRRRRSRESTGSQPVLGLGAIRSEQMAAIAKKQLRVQMAWNAFYVFAWYSCSSALSFYNKWLFSPNHHNFQFPLFTSSFHMVAQFLLSSLTLAIMPYLRPKAAPSAKDFGTKIMPCAVASGLDIGLSNSSLKTITLAFYTMCKSSSLAFVLLFAFAFKLERPTWTLAGVIAVICVGLFMMVMSEVDFVLIGFIQVMLASVLGGLRWALTQILLEKSDTKSGSLNNPISTIFFLSPIMGVCLGIVSGIFEGFGTIFTSPFFETAAKGLSTMGLVFLGGLFAFLMVLAEFNLITRTSVVSLSVMGIVKEVATILVSSVVFHDHLTLVNILGLFITLTGIGFYHFMKLREIMAKSRRDAKELADAQQEKAAKKKERASARKSRGKQSDGGGGGGGEESSGSGGSGGAGSNSRMLEYKDSDRDASILEEEPWNVSLAPPNAKGARKDSLQDDEEVFILDDDDEVGHASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0C7</accession>
    <name>A0A9P6T0C7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BGZ80_009579</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000587">
        <property type="protein sequence ID" value="KAG0015871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0C7"/>
    <dbReference type="OrthoDB" id="424465at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000987">
        <property type="term" value="F:cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.650:FF:000045">
        <property type="entry name" value="F-box protein At1g78280"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041667">
        <property type="entry name" value="Cupin_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050910">
        <property type="entry name" value="JMJD6_ArgDemeth/LysHydrox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12480">
        <property type="entry name" value="ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12480:SF21">
        <property type="entry name" value="JMJC DOMAIN-CONTAINING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13621">
        <property type="entry name" value="Cupin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="7">
        <location>
            <begin position="67"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="JmjC" evidence="8">
        <location>
            <begin position="269"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="526"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="552"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="569"/>
            <end position="578"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0015871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="578" mass="66522" checksum="20F486610EA90AC2" modified="2023-09-13" version="1">MPTHEAPMAARQPPAKKQRFIIRHEKPKMTTKHIMSLQHPLGIKPLGNYYMDATRPDFPGSCRGPSLGQLSRLTDEILLEVLNLLPPLDLLNLGATSKVLYALTHLDDMWKNLTITQFKGDWTWEGDSWRATYLKRSDPTYDASIILKNRDQMKLKTFYSDVLFQPFYCAAIGMEPYVGVENIDRRSQLTLEQFVEEYERPGKPVIIADGAQHWPAMKKWSTEYFLQKWPESVLRAESVDVTLTNYFKYAEGTKDESPLYLFDKNFGERCDGILDDMEVPPYFREDFFGMMGEKRPDYRWLIVGPARSGSTFHKDPNATSAWNTVITGSKKWIMFPPHILPPGVFTNEDESEVTSPVSLMEWFSNFYASTQLPDDPADRPLEGICREGEIMFVPRGWWHAVVNLDDCIAITQNYVGSQNLKETMQFLYMKRDQVSGVVDERREGLYEEFKESFFKSNQIPEKQDQADTESLSEEETKKRKQLIEIWTKYEQEIKDLSTAIKRCRGEHEQVDGAPERLSFWEQAKLGLNNKTDGEESTKQETTSGGFSFGFDFGDDDEAEQVEAEKIESGNDNDTNSNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0G9</accession>
    <name>A0A9P6T0G9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Coth-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_009647</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000597">
        <property type="protein sequence ID" value="KAG0015762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0G9"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014867">
        <property type="entry name" value="Spore_coat_CotH_CotH2/3/7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40050">
        <property type="entry name" value="INNER SPORE COAT PROTEIN H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40050:SF1">
        <property type="entry name" value="INNER SPORE COAT PROTEIN H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08757">
        <property type="entry name" value="CotH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="559"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="523"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="534"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0015762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="582" mass="64326" checksum="41A67322D3536278" modified="2023-09-13" version="1">MVTFNCVGYPSTTGGSFGVSIAGAITKLTTSDSTFPVWSGSVPGTTSSVQYSYVELDSTGSTVKSEAFTRQLTQTTDTRTYNEFFERPTTIFNITRLPYTYLATYPSETKAFNEDQIATLHITGPVDSINFMNSQPNNDTDVRVDFRFITADMIYSQTNISFHTSGESSKDYAKQSYKLKFDSDYKQTFFSRPNIKLRSEATEPTHLREKLYIDMLNSVGVPTAQGCYVRLYINNEGYGLYLMVDDIKKSFIKQTIYGGDGNIIPGSLIQANAPTVDDQADLVYKGSNSTNYDPAVYVSQNLGNNPSSNPLGQLITFMSDLQTFDPVTTPNPVDYWTSRLDLDGFLRNMALEYLMGGYDQYWWSGSNYFIYFNPVLSTTGKWQWVPTDFDGTFGNGPVDDANATYKNYYNFQPDHPLVSKLIINNTAINAQFEQILKEIVSTAFKPEAMNAHIDSLHSMISLDAQWDCSLTRYSPGTNQNYTFEDFNNNLIEPVADMGAGLKPWVESRAKTVAAELGFTIPAGTADRVAPPPRNNNKGKGDSSSPANGKNGKGSSAASFALSLPISGFSFIAMLSSCLILLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T0U5</accession>
    <name>A0A9P6T0U5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_009798</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000619">
        <property type="protein sequence ID" value="KAG0015531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T0U5"/>
    <dbReference type="OrthoDB" id="2429193at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009467">
        <property type="entry name" value="Glycolipid-bd_prot_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06475">
        <property type="entry name" value="Glycolipid_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159275">
        <property type="entry name" value="PA1994-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="149"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0015531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="430" mass="46873" checksum="9DD1B1AFCF673050" modified="2023-09-13" version="1">MTHSTSSPRSTTPTPSDSLTGRHLIYRGLTKSSMEYMSLSHSNRHPEAAHTLKGEILISGKNQPGYIQYNITLDQEWMTRRVILTAVFDGSQEKRLVLEVDQDQRWYKVTEHRLARSRSFFRSGVNSPANNVNGTATTSSSPRPSNLGRDTSSTTTSEDSSSLSRVSSESLSSASSMQDVDTSFSDVSSYCSSSSFSSSSSDVESSIPFEKINLTWTPPPKGTKRGSKRFSSFNPLKDVHPSLSSSPPSATNSCATTNFSASSPPQQPPTVLRSPVIEFANRTLSKSSSSSSLNGSSSTTQKTYEHIPSLDGCIHLDLGSDISPSTLLLPVRRATLGIDPDEMRDHLASLMSCPSAVTSELTAMVSFPDLSLRRVRTHVAYVGQGSDETLSIVERWTDEDDDDLDSTLVEVDEDGLVVRYGDAWARLRTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T121</accession>
    <name>A0A9P6T121_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6589 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_008954</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000505">
        <property type="protein sequence ID" value="KAG0016753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T121"/>
    <dbReference type="OrthoDB" id="2496395at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046496">
        <property type="entry name" value="DUF6589"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20231">
        <property type="entry name" value="DUF6589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6589" evidence="1">
        <location>
            <begin position="2"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0016753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="168" mass="19117" checksum="1BB2C467CB2BF6D6" modified="2023-09-13" version="1">MSSWLINTTGTEDGWIPADMYQEHNNLLTKVIYSAKGSNLTHEVLEKKISTNIRTFDEVMSTMMTEFGVPKRSSKHSTVRADEEIEKLVKTLRDNGNLDRVPAVEERTKPMVDLFGLGMIKLAHSKRLDDFKRQNQDVGLESYGGPSDSEDFVHSTILDADDYIENYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T140</accession>
    <name>A0A9P6T140_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transcriptional activator spt7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">SPT7</name>
        <name evidence="9" type="ORF">BGZ80_008258</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000442">
        <property type="protein sequence ID" value="KAG0017469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046695">
        <property type="term" value="C:SLIK (SAGA-like) complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05510">
        <property type="entry name" value="Bromo_SPT7_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22927">
        <property type="entry name" value="HFD_SPT7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018359">
        <property type="entry name" value="Bromodomain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006565">
        <property type="entry name" value="BTP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037782">
        <property type="entry name" value="Spt7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47343">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR SPT7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47343:SF1">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR SPT7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07524">
        <property type="entry name" value="Bromo_TP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00576">
        <property type="entry name" value="BTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00633">
        <property type="entry name" value="BROMODOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Bromo" evidence="8">
        <location>
            <begin position="481"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="121"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="180"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="328"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="580"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="800"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1225"/>
            <end position="1831"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="121"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="183"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="200"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="348"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="581"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="609"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="654"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="800"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="814"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1265"/>
            <end position="1308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="1323"/>
            <end position="1334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1356"/>
            <end position="1373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1394"/>
            <end position="1416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="1417"/>
            <end position="1426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1445"/>
            <end position="1734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1757"/>
            <end position="1774"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0017469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1831" mass="205317" checksum="562E83EEE3D77B5B" modified="2023-09-13" version="1">MPFPFPDGNAGVDDIDVNMETHTISSLSSSSSEQKEQLLKILNDPSTNSQTRLTYNVAQEMNTRRLWRFYLSEEEHEIFEAALSSLDSWQSFISLDGKFGLQLEEIKRQREQEKQYLQIQANSLENSQSESVPNIESTEIEDTKDANLDSVDQLPDIVKVEVADQEEIFSDIESANIKKEDSLSVPDSLSVSTPPVSTPNGQLRSLHTPNYTGSPSPRDNRDSQPPNDPSQPEVPSSHSPEPISTPISVPASIPTTAFRSRVMVFEQLLPKLYPSHGGCCHPIVDIQEMENRDPLKHDKVGEILASLTSQGSRTRFAEDDDYDVDMESGMKQEENSAGPNKGAVPEVPKGEKGQETKLDNSPLRLPIHHLYYTLEYDMDAMIEQQQLEEADKSIQQEQENQTGSSLVTDNMLTQLGAGSLSMKYLLGAIEANRAATGLTDRELRTLLSDVRPNRSKWANEDKVGQEELYEGCERILMELRNYTEHSTPFLNKVNKREAPDYFQIIKHPMDLGTVLKKLKAFAYQSKTQFANDLYLIYSNCLLYNSDPSSVYRKHAIAMKKKTQQLLETLQDVVIRDRAEVEAEAEESEDEGDGQAGRPNESTKGVGRMEQSSKGLPANGGSSKNSKGHPSKRGAAAVPLGSETPKMSMDLDSMGNATPTRETSREPSTMDSAETPFLERSGLGRSGTPNGPLLGSPARYSRMSRASVPVEIDLEQEEKDIAAELNADRGDILFQDWKEKTKKVRARICSVRESQQQQRFEDRVALERSPWEMKKSRDIELAHDSIFDTLAHKKQKKKKTLSFNLDKSGSSAEAVADEPDPYEDVYGDSDSDDDDENEDDYVRDLFAPPKLKEEKMQKKKTSNGIFLPEYAVRSGLPEVPGFGHERLDDPEVARKYFEESEISAIEEKQPSLSLYPSAVAAPGHLTAGIERNVEELRKIRHVYSKIFAARATIPEAIQIEEPIELVPIPPHEGPLPPLIMNSATGNAMLSRVASKLLAHAGFQGAQASALAVMTDITVDFFLNLGRALRGYTDLYNKTMTAEEILLHTLYENGVGSVGELEGYIREDVERYGNKLQDIHRKLETSYSDTLNNLNENEVADADFEYQENDEAFLNGNFIGGGAVGADDLGDDFFGFRELGLGTITIPSRIWYGGQRDGLPSKSGVGGSGLIKAKDPKPALPYPPPPPFKPLMDPTATIGLLHSFFKKRMDDLGSLMEDEFMPVSRRVAARPKIPPTGKIVSSMKKRSNKPGELSALAEAKKRKRKKEKDAQEAERAERKKQKQDAKDKKILEKLEKKKLKEESKIKEKLAKPTKKGKKAASEGPGEGEGDEDDSDAEPPKSSIPRDSPDPMPPPATIPLPKTGSSSTSSSSIAIPPTTPKKPKKPKAPVKSATPSVGSSSTPMFVTPPTSMLSSSNSTDGEDMEEEVMESGGGNMLPPKPTPPQTKSGDDTPKPSSKSSKDGKDKDKDRDKDKDEKKERSKDKDKEKDKERSKDKDKSDRESLSEREKDKDREPSSKSSSGHKESKSKSSKDKEKSSKDKDRSERERDSSDKEKDRDRDRDERDRSERSERDRDRSERDRDRDRDRDRERSDRSDRSDREREKSGGSGSGRDRDRDRDRDRDRDRSDRSDRDKDRDRDRDRDRDRDRDRSDRDRDRDRDSYRERDRDRDRDRDRDRDRDRDRDRGDRDRDRDRDRDRDRERDRDRDRDRDRDRDRDRDRDRDRERDRDRDRGDRDVNGVSNSGSNGSLGGGGSGHHKNGSNSSSKDRGPSSSSSSSFKDKSSIDAASSTSSQIPLTSKKKKKAGVLDGSPGPSPTKKKKTSSAVPIPPSFLDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1I4</accession>
    <name>A0A9P6T1I4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BGZ80_007475</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000384">
        <property type="protein sequence ID" value="KAG0018173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T1I4"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="49"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="178"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="229"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="267"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="308"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="348"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="426"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="315"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="348"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="442"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="502"/>
            <end position="521"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0018173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="521" mass="58532" checksum="C7F6B19B7D399186" modified="2023-09-13" version="1">MTHQSDYSFVQRAVANGWFYLWFVVYAFRYDRFMALNFRRVMRFELRSIVTLLLLIAIPLHLSYDIGLSTIKYYEGFIINPENNETLSKPYYLWSQPHQDLASVLDYTLACAMALFASIFFLLQSFYHYISKSVTKSSFMSSLEFRINIICSVILIAAFPLVQYLARNDHNKREAAPQMAFSLVTCSIGVLGIRSNFRFKSLLKVALMTMTESSQDVAEKLEHFKDMNMILTISMFGTGIPLAIASVDGLTPNPVIAANKFASDFLVMNVNFFEFIIWVTVVLIFYPRRTVVGSTFGVSSGGGTLSRTVPASARQNNNNNTFNNININTNQNQGDFIKTINGDSCDNNSYNNSNNNGGYASPSRSYSTSKERPPSIVPYKAPNDTRNFGDTMPLTRIREVDTAEIVQMEAFKSMYDINASSDAPIFLTSPTSPTKPRYEGPTSLTLSPEQSRMASPSFGSGTLRSPKQPTTRVGQQTFVLEVATDSNQSQERQQGQDDYNRVRTPTTPTRPPKGYRGPPSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T1I9</accession>
    <name>A0A9P6T1I9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="17">DNA repair protein rad2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">RAD2</name>
        <name evidence="17" type="ORF">BGZ80_007881</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the XPG/RAD2 endonuclease family. GEN subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the XPG/RAD2 endonuclease family. XPG subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000412">
        <property type="protein sequence ID" value="KAG0017822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048256">
        <property type="term" value="F:flap endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09904">
        <property type="entry name" value="H3TH_XPG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09868">
        <property type="entry name" value="PIN_XPG_RAD2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.20:FF:000030">
        <property type="entry name" value="Flap endonuclease GEN-like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036279">
        <property type="entry name" value="5-3_exonuclease_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008918">
        <property type="entry name" value="HhH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006086">
        <property type="entry name" value="XPG-I_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006084">
        <property type="entry name" value="XPG/Rad2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001044">
        <property type="entry name" value="XPG/Rad2_eukaryotes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019974">
        <property type="entry name" value="XPG_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006085">
        <property type="entry name" value="XPG_DNA_repair_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16171">
        <property type="entry name" value="DNA REPAIR PROTEIN COMPLEMENTING XP-G CELLS-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16171:SF7">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00867">
        <property type="entry name" value="XPG_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00752">
        <property type="entry name" value="XPG_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00853">
        <property type="entry name" value="XPGRADSUPER"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00066">
        <property type="entry name" value="XRODRMPGMNTG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00279">
        <property type="entry name" value="HhH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00484">
        <property type="entry name" value="XPGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00485">
        <property type="entry name" value="XPGN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47807">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00841">
        <property type="entry name" value="XPG_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00842">
        <property type="entry name" value="XPG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="XPG N-terminal" evidence="16">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="XPG-I" evidence="15">
        <location>
            <begin position="1002"/>
            <end position="1071"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="157"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="336"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="460"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="788"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="827"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1267"/>
            <end position="1348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1377"/>
            <end position="1523"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="958"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="160"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="354"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="792"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="829"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="856"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="889"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="1296"/>
            <end position="1309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="1334"/>
            <end position="1347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="1383"/>
            <end position="1399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="1406"/>
            <end position="1423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="1428"/>
            <end position="1439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="1470"/>
            <end position="1495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00038112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0017822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="1523" mass="169993" checksum="7629D81D309BAB16" modified="2023-09-13" version="1">MGVKGLWELLHPVARPIKLENLSNKHLAIDASIWLHQFLRGMRDKEGQVISNAHIIGFFRRICKLLYYNIKPIFVFDGGTPALKRLTIQERRRRKKQDANMVKRTAERLLAAQLRLHALEQRKAARKKKAVEENSLAGVVHDSDENPKYLDEIESDVPQAGNTDSQTDSKTNDGTAVGSQAKRIKDKYLLPPMEVDFETLSKIRSNDERFGYQPEDEVGHFLDGLKKESGLANIDSDVFKALPSEMQYEILQDIRHRSRVTSYERVQEMVRLSNTPMDFSKLQVQGVIRRHNVTHKLLTVNQTVSRIESTVKPGRIASQRNRQYILVKNEEGGWVLGGKKPTTGNTADKPVQLDSDDDEIKPENEIKEEEGEDLDSDEDIELEEVTIPLITSSPATDNSFKSDVEVKPMPAQLATPKPTPKPTPKVDESNLLINHLEAYMDEDESIEKVMAKFAEIEDQAARKGGSGVAPLPTTDRNYEEDSTNRKNGLHLIRESDVIHVQDGARQHLAKAGLRLKSDPQWPEVISDDEEMASLDTLYSLDTLHSDNTVDYDDFEDMVEDEETGEIISRGAYNRRYQRQISPEASIGRALSIVEESNLQLEAFHSYWTGYTPDFFKVKNQDYEQMIKDAIYDWDDDRVEAEVRSATRKLEKSSVNDILGVEALNFWKSFLESLLNRRQVQLNSASQPVVVDLDEPEPQTGKSLPTKERKSRLSQLISLDDDDDDIVFDAKETYKDRLLQQQAAPVELEVEKSTPIHVTSLKSTSDDSTLSRRPILDFSSSIELERPNVPVSVESTPTKPALSTSDSPTRLNLVVSDDEGTELGAVIDASTSDSGAGSLISSSRPDSEVAVVPSFDKGFDHVSGDEIDHPTTEDSIMLDQDSGESHVEAIPDDEGDGEDEDEDEEDDVDEADLETEEQGFTNLFPDMATLPGAILNAKELEQEPSFSKEERAILEQQEAKKMFEESRQLESEIKVLRDQHRKHQRDADDLTESMVAETQTLLRLFGIPYLVAPMEAEAQCADLQLRGVVDGILTEDSDVFLFGGARVFKNMFKEEKFVECYLMSDIERDLGVGRERLVALAYLLGSDYTTGIKGVGLVTAMEIIRLFPKLESFARWWRGEQQKANGSGEKDNENTVGLTEMELDSIDEVALEKLAKQCKKIHMPSTFPDPHIFDAYVRPLVDDDPAKFQWGIPDLDGLRDFLRKSLGWDRGEVDRVLLPIIRQMSSTENQMQTTLDGFFDVSAGMGSFQPLPKNNLYKSARLRKVVDGLKGQNSGNQSGGEGPESDGDKDGAATTATKKKTAAKRKLATKKAKETSNATEGDIDVTDVGAQAGVENDDEDDEEGFLDELEFKKRKTSRTSSLKKTRVAQTKVPEAVTAAKQNLKSKDVHLKLAARNKDRAAAAAEDDQSKNSKQAKRDDTDRNGTSDSDSSDDDEKDQDDLAPSHWDLLAERQRQQQLEQQQSPRKGNGPSGPTVTSSSIVSGRASSLTAIVSASNAARYGSGSFRNKETGTTGSQKKPSAKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T236</accession>
    <name>A0A9P6T236_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11 12">Cytochrome b-c1 complex subunit Rieske, mitochondrial</fullName>
            <ecNumber evidence="12">7.1.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BGZ80_005558</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a quinol + 2 Fe(III)-[cytochrome c](out) = a quinone + 2 Fe(II)-[cytochrome c](out) + 2 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:11484"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="7.1.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
        <text evidence="12">Binds 1 [2Fe-2S] cluster per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="13">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="12">The Rieske protein is a high potential 2Fe-2S protein.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Rieske iron-sulfur protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.8" evidence="12"/>
    <dbReference type="EMBL" id="JAAAID010000274">
        <property type="protein sequence ID" value="KAG0019595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T236"/>
    <dbReference type="OrthoDB" id="1637982at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008121">
        <property type="term" value="F:quinol-cytochrome-c reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd03470">
        <property type="entry name" value="Rieske_cytochrome_bc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.102.10.10:FF:000001">
        <property type="entry name" value="Cytochrome b-c1 complex subunit Rieske, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="entry name" value="Rieske [2Fe-2S] iron-sulphur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.270">
        <property type="entry name" value="Ubiquinol cytochrome reductase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037008">
        <property type="entry name" value="bc1_Rieske_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014349">
        <property type="entry name" value="Rieske_Fe-S_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005805">
        <property type="entry name" value="Rieske_Fe-S_prot_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004192">
        <property type="entry name" value="Rieske_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006317">
        <property type="entry name" value="Ubiquinol_cyt_c_Rdtase_Fe-S-su"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01416">
        <property type="entry name" value="Rieske_proteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10134">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT RIESKE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02921">
        <property type="entry name" value="UCR_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00162">
        <property type="entry name" value="RIESKE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="ISP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81502">
        <property type="entry name" value="ISP transmembrane anchor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="12" id="KW-0249">Electron transport</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="12" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Rieske" evidence="14">
        <location>
            <begin position="130"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00072517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0019595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="227" mass="24377" checksum="240C69453FDE847E" modified="2023-09-13" version="1">MASLATRLASASLTRSARVAAARNVLAPAGLAAQVRLNHTTARETTDIPNFDKYKSGSGDVSNRAFSYFMVGTTGALSFVGAKTTVADFLANMSASADVLALAKVEVDLNSIPEGRNVTIKWRGKPVFIRHRTADEIEEANSVNIAELRDPQNDAERAQKPEWLVMLGVCTHLGCVPIGEAGDFGGWYCPCHGSHYDISGRIRKGPAPLNLEIPTYSFEEGNKIVIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T266</accession>
    <name>A0A9P6T266_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Flavin-nucleotide-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">BGZ80_005256</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000260">
        <property type="protein sequence ID" value="KAG0019800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T266"/>
    <dbReference type="OrthoDB" id="444432at2759"/>
    <dbReference type="Proteomes" id="UP000703661">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024747">
        <property type="entry name" value="Pyridox_Oxase-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34071">
        <property type="entry name" value="5-NITROIMIDAZOLE ANTIBIOTICS RESISTANCE PROTEIN, NIMA-FAMILY-RELATED PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34071:SF2">
        <property type="entry name" value="FLAVIN-NUCLEOTIDE-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12900">
        <property type="entry name" value="Pyridox_ox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0019800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="238" mass="26534" checksum="78DB7BF0266E4714" modified="2023-09-13" version="1">MATDFTPTSHKAINQVHRLKDRARYDTESIHAILDNNLLAHVGFTLPPGAADEDDWPFVMPMCYGRIEDIVYLHGYVSGRMMKALASEERPKVCITVSQVDALIVAMSPFHNSMNYKSAVVFGHGRLVESPEEKDRALAAITNQPFRHADRWNDSRPPNSIDLKSTKVIAVQIERASAKMRTGGVSDDILDKEDPELLKKHYSGIIPMKTVFGAPEPTAYNIADTPAYLLPDAMNKEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2R8</accession>
    <name>A0A9P6T2R8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BGZ80_003861</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000205">
        <property type="protein sequence ID" value="KAG0020635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="192"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="335"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="467"/>
            <end position="493"/>
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            <begin position="613"/>
            <end position="637"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="655"/>
            <end position="674"/>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="681"/>
            <end position="718"/>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="753"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="24"/>
            <end position="43"/>
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    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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            <begin position="44"/>
            <end position="60"/>
        </location>
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            <begin position="61"/>
            <end position="71"/>
        </location>
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    <feature type="compositionally biased region" description="Basic residues" evidence="1">
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            <begin position="72"/>
            <end position="90"/>
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    <feature type="compositionally biased region" description="Low complexity" evidence="1">
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0020635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000703661"/>
        </source>
    </evidence>
    <sequence length="893" mass="98904" checksum="6EA2620E895D2439" modified="2023-09-13" version="1">MTGTSHQAFPGTATPTTCSHEPRASNANTNHNTTVHNTHVTSAGDSQPISTLKEVQNPEGSKTSKLLSRSRSPTRRISRSRSRSRSRSRSSSRPITPQGPVSARTHTRSKSAASEFWSRTISEALLKKELVPSSFPISKARPSILTRGFSAESTSTQEMDHRNRDAGGGSVNESSGRKTTAKERFVAIITRNSGSSTPPTTNTEVVSGTHDNSLSRSFQEGIDERSSLRLSHSPILNQTHSRRQGSPSVGRSGFNDQLGTSPTRPVEGMMGFPYNNSSVLMSTPRMTPNLRTTRQSKPRPFSVATMEKVLESTGQQNGVEQRQESPRHFIFRDRQDHQTQSSFRHQNFTHAEKANENSATRPRMIGSGSHPLLATLSSFQDSSVHPVDGSNERSNKGKETEHNYETNSGVKSFDTKRLPRPILEDLATTNGSLHVHEHHIHHHYYCQHCPPLIHPGTGEIEKPEKRYSTVGRRRRPDSTPLMFGSSASQHPRRSSILDVGFSTSPIEDGHPFALPLDENSNVKPVVNKKKKSILGTMSMTSSMRKRFFAEQKKEQAQPASQTHGTHRRLSIPFFSSQPKYEEGPAVMCHKDGPYGPAGATIRARRNQIQFPLAELSDEEDDEFGTGSVPPSEDNSNQQRAKFLSKLKKFLLRPSPFAKNSGVSQDNSGSASTMPTDIRSAATVRESKSHWSRSGKNLPAHFDQNEYDSDDNSSEAPPIFPARQRTFKRWTHQGMFEPPVSTLQRRERIDIRTQFQQSSPTTQERHYQLQYHHHHHHHHDSSSSQEHHHHHHGTISKQQSEQRPSSQRQITSSSDIIAAGTTTSDSPQSVDSNNGRSVKSPVTSILSSLPVSTMNDKDLSDHDTTPTTCSTSPTAAKPILTASGHLPSINASVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2023-09-13" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A9P6T2V9</accession>
    <name>A0A9P6T2V9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BGZ80_003920</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Entomortierella chlamydospora</name>
        <dbReference type="NCBI Taxonomy" id="101097"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mortierellomycotina</taxon>
            <taxon>Mortierellomycetes</taxon>
            <taxon>Mortierellales</taxon>
            <taxon>Mortierellaceae</taxon>
            <taxon>Entomortierella</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="Fungal Divers." volume="104" first="267" last="289">
            <title>Resolving the Mortierellaceae phylogeny through synthesis of multi-gene phylogenetics and phylogenomics.</title>
            <authorList>
                <person name="Vandepol N."/>
                <person name="Liber J."/>
                <person name="Desiro A."/>
                <person name="Na H."/>
                <person name="Kennedy M."/>
                <person name="Barry K."/>
                <person name="Grigoriev I.V."/>
                <person name="Miller A.N."/>
                <person name="O'Donnell K."/>
                <person name="Stajich J.E."/>
                <person name="Bonito G."/>
            </authorList>
            <dbReference type="PubMed" id="33364917"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">NRRL 2769</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAAAID010000207">
        <property type="protein sequence ID" value="KAG0020604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A9P6T2V9"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14705">
        <property type="entry name" value="bZIP_Zip1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    
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